Study Desmedt-ER-neg

Study informations

165 subnetworks in total page | file

2310 genes associated page | file

Enriched GO terms page

General informations

General Index page

Study Index page

Subnetwork 6306

score

Expression data for subnetwork 6306 in each dataset

IPC | Loi | Schmidt | VanDeVijver | Wang |

Subnetwork structure for each dataset

Score for each gene in subnetwork 6306 in each dataset

Gene Symbol	Links	Frequency	Frequency Rank	Subnetwork score rank	Global rank	IPC	Loi	Schmidt	VanDeVijver	Wang
EP300		113	4	1	4	-0.149	0.087	0.102	0.052	0.025
TEK		18	86	83	95	-0.149	-0.049	0.174	0.015	0.113
PAX6		22	69	318	312	0.259	-0.003	0.112	undef	0.168
SORBS1		57	19	1	13	-0.043	0.015	0.314	-0.072	0.200
TP53		85	7	1	6	-0.167	0.148	-0.027	0.252	0.147
TPX2		5	360	412	416	0.114	-0.121	-0.018	undef	-0.056
RCHY1		2	743	2080	2055	-0.035	0.007	0.245	undef	-0.026
ADD2		8	222	614	599	0.113	-0.022	-0.061	0.270	0.180
ERBB2		141	1	1	1	-0.103	0.092	-0.090	0.267	0.046
CDKN1A		110	5	1	5	0.064	0.254	0.030	undef	0.082
PRKCA		63	15	1	10	-0.016	-0.088	0.174	0.095	0.005
EIF1B		8	222	1576	1529	0.149	0.075	0.332	-0.017	-0.070
CDK3		7	256	590	570	-0.076	0.189	-0.041	-0.089	0.082
RPL23A		5	360	842	828	0.208	-0.007	0.024	-0.242	0.055
HEY2		8	222	570	555	-0.045	-0.021	0.398	-0.024	-0.058
NELL2		7	256	727	714	-0.005	0.138	0.421	-0.027	0.074
CDH1		37	32	296	278	-0.227	0.187	-0.236	0.137	-0.024
CTNNB1		43	25	83	81	-0.113	0.187	0.159	-0.090	0.239
CDH3		1	1195	2301	2301	0.028	0.169	-0.055	undef	-0.027
LIN7A		6	301	366	377	-0.189	-0.074	0.108	0.065	-0.146
ST18		16	104	236	227	-0.131	0.028	-0.088	0.186	0.151
TWIST1		50	20	1	14	0.044	0.194	0.061	undef	0.219
POLE3		17	95	141	138	-0.083	-0.033	0.231	0.096	0.011
KIT		39	29	1	18	-0.130	-0.091	0.235	-0.046	-0.059
TRIP13		2	743	1055	1059	0.043	-0.199	-0.017	undef	-0.146
PTPRK		14	117	83	96	0.156	0.141	-0.094	0.048	-0.024
ZNF638		5	360	806	784	0.164	0.088	0.020	0.077	-0.045
RPL35		8	222	1323	1280	0.108	-0.012	0.370	-0.145	-0.220
GABPA		23	66	696	665	0.033	-0.183	0.066	0.141	-0.161
AKT2		28	47	412	394	0.110	-0.118	-0.003	0.088	-0.092
FEZ1		8	222	141	149	0.047	-0.020	0.154	0.165	-0.128
BRCA1		3	557	1534	1516	-0.201	-0.078	-0.087	-0.166	0.168
VEGFA		68	14	83	78	0.090	0.200	0.030	0.095	0.148
ALCAM		8	222	1	46	-0.208	0.193	0.067	0.088	-0.010
MAP3K4		1	1195	2301	2301	0.059	-0.015	0.000	-0.169	-0.092
ENPP1		5	360	1055	1034	0.088	0.129	-0.026	undef	0.039
GADD45B		8	222	318	325	0.158	0.122	0.067	0.060	0.212
CCNA1		33	37	412	393	0.174	0.092	0.078	0.055	-0.098
GSK3B		79	8	179	169	-0.130	0.292	-0.129	0.291	0.057
KLF5		76	9	1	7	0.077	0.117	-0.007	-0.110	-0.006
TCL1A		3	557	1450	1430	-0.152	-0.166	0.090	undef	-0.066
RPL22		3	557	1576	1548	-0.266	0.105	0.059	-0.143	0.112
ANGPT1		5	360	696	680	0.106	-0.167	0.084	-0.035	0.250
EYA2		13	124	318	316	-0.034	0.113	-0.142	undef	-0.019
TGFB1I1		49	22	1	16	-0.105	0.229	0.143	0.195	0.298
PFKP		6	301	83	105	0.195	-0.076	-0.040	undef	0.094
DCAF13		2	743	366	395	0.049	-0.211	undef	-0.060	undef
PSPH		20	81	366	356	0.240	-0.019	-0.102	0.358	0.025
SLC30A9		2	743	83	123	0.089	-0.011	0.026	-0.104	0.050
POU3F2		17	95	928	891	0.135	0.114	0.155	0.253	0.040
NCOR2		32	40	318	290	-0.096	0.211	-0.163	0.158	0.114
MCM6		1	1195	2301	2301	0.162	-0.181	0.021	0.010	0.199
PLSCR4		13	124	318	316	-0.069	0.140	0.231	0.212	0.212
MUT		1	1195	2301	2301	0.088	0.056	-0.051	0.294	0.183
FN1		6	301	590	582	0.190	0.133	0.091	undef	0.083
EGR1		39	29	1	18	-0.184	0.259	0.130	0.018	0.122
GADD45G		43	25	141	134	0.030	-0.029	-0.207	0.201	-0.055
LYAR		2	743	1803	1782	0.037	-0.154	undef	-0.245	undef
ASAP1		1	1195	2301	2301	0.036	0.070	0.035	undef	-0.056
PFKL		7	256	83	102	0.056	0.106	-0.173	0.160	-0.158
PTEN		27	50	141	135	0.045	0.055	0.017	0.183	-0.041
AMH		10	167	366	362	0.103	0.056	0.113	-0.187	0.301
GHR		35	34	83	83	-0.112	0.174	0.090	0.176	0.201
NEK2		8	222	141	149	0.292	-0.106	0.020	0.083	0.165
GTF2F2		4	440	957	942	-0.059	-0.085	0.119	-0.004	-0.054
WT1		33	37	1	21	0.254	-0.039	0.036	undef	0.172
FLI1		2	743	1	66	-0.021	0.018	0.067	-0.175	0.009
IGF2BP1		15	111	366	359	0.135	-0.036	undef	0.190	undef
CCND2		5	360	1492	1453	0.022	-0.011	-0.072	-0.153	-0.029
SP1		72	10	83	77	0.222	-0.254	0.239	0.020	0.082
ERG		9	196	179	195	-0.134	-0.026	0.235	-0.027	0.182
PLSCR1		10	167	412	408	0.202	-0.159	0.091	undef	-0.105
COL4A4		6	301	83	105	0.102	0.155	-0.039	0.295	0.068
PIK3R1		127	2	1	2	-0.237	0.381	0.065	undef	-0.002
PACSIN3		1	1195	2301	2301	0.270	0.129	-0.045	0.016	0.066
UTP15		2	743	366	395	0.266	0.140	undef	undef	undef
ITGA5		26	52	179	177	0.031	0.192	0.125	0.133	0.202
IMP3		4	440	366	381	0.042	-0.132	0.113	-0.304	-0.196
PFKM		6	301	83	105	-0.030	-0.079	0.293	0.023	0.118
MGMT		5	360	366	379	0.184	-0.022	0.201	undef	0.196
XK		18	86	179	187	0.154	-0.000	0.067	-0.123	-0.040
BAIAP2		3	557	412	430	-0.077	-0.025	0.099	0.092	-0.051
NR2F1		25	59	83	92	-0.252	0.113	0.133	-0.116	0.207
EGFR		117	3	1	3	-0.195	0.240	-0.205	-0.187	0.065
MAP1B		69	12	1	9	-0.123	0.263	-0.107	0.304	0.100
BCAR3		2	743	2111	2085	0.271	0.123	0.259	-0.027	0.066
INSR		96	6	236	221	0.063	0.173	0.135	-0.014	-0.072
NEK1		15	111	141	139	0.032	0.184	0.049	undef	0.135
POLE2		4	440	727	723	0.200	-0.203	0.049	0.000	-0.010
CDC27		6	301	1010	986	0.156	-0.086	-0.029	0.006	0.348
SH2B2		2	743	1010	1007	-0.006	-0.062	-0.069	-0.056	-0.111
HTT		14	117	141	140	-0.016	-0.015	0.075	0.092	-0.093
GRB7		58	18	1	12	0.021	0.115	-0.072	0.229	0.129
IGFBP5		48	23	83	80	-0.076	0.110	0.074	0.278	0.181
AR		46	24	141	133	-0.163	0.081	-0.035	0.178	-0.030
AURKA		3	557	1165	1151	0.189	-0.176	0.100	-0.051	0.050
ATN1		7	256	412	414	-0.005	-0.093	0.005	-0.185	-0.136
TIE1		18	86	366	357	-0.108	0.005	0.141	-0.108	0.252
CDK2		31	43	179	174	0.196	-0.096	0.109	0.001	0.362
CDKN2A		60	17	1	11	0.263	-0.113	0.111	undef	-0.105
IGF2		14	117	570	553	-0.022	0.172	0.145	0.087	0.116

GO Enrichment output for subnetwork 6306 in each dataset

IPC file

Name	Accession Number	Link	P-val	Corrected P-val
negative regulation of cell-matrix adhesion	GO:0001953		1.168E-08	2.852E-05
regulation of cyclin-dependent protein kinase activity	GO:0000079		1.342E-08	1.639E-05
cellular response to insulin stimulus	GO:0032869		1.542E-08	1.255E-05
phospholipid dephosphorylation	GO:0046839		1.717E-08	1.049E-05
negative regulation of phosphorylation	GO:0042326		2.38E-08	1.163E-05
negative regulation of phosphorus metabolic process	GO:0010563		4.018E-08	1.636E-05
negative regulation of protein kinase B signaling cascade	GO:0051898		5.12E-08	1.787E-05
insulin receptor signaling pathway	GO:0008286		5.133E-08	1.568E-05
response to insulin stimulus	GO:0032868		7.241E-08	1.965E-05
negative regulation of insulin receptor signaling pathway	GO:0046627		1.187E-07	2.901E-05
negative regulation of focal adhesion formation	GO:0051895		1.187E-07	2.637E-05

Loi file

Name	Accession Number	Link	P-val	Corrected P-val
negative regulation of cell-matrix adhesion	GO:0001953		1.581E-08	3.805E-05
cellular response to insulin stimulus	GO:0032869		1.913E-08	2.302E-05
regulation of cyclin-dependent protein kinase activity	GO:0000079		2.135E-08	1.712E-05
phospholipid dephosphorylation	GO:0046839		2.194E-08	1.32E-05
negative regulation of phosphorylation	GO:0042326		3.406E-08	1.639E-05
insulin receptor signaling pathway	GO:0008286		5.746E-08	2.304E-05
negative regulation of phosphorus metabolic process	GO:0010563		5.746E-08	1.975E-05
negative regulation of protein kinase B signaling cascade	GO:0051898		6.539E-08	1.967E-05
response to insulin stimulus	GO:0032868		9.342E-08	2.497E-05
negative regulation of insulin receptor signaling pathway	GO:0046627		1.516E-07	3.647E-05
negative regulation of focal adhesion formation	GO:0051895		1.516E-07	3.316E-05

Schmidt file

Name	Accession Number	Link	P-val	Corrected P-val
cellular response to insulin stimulus	GO:0032869		3.534E-08	8.129E-05
negative regulation of phosphorylation	GO:0042326		7.559E-08	8.693E-05
insulin receptor signaling pathway	GO:0008286		9.996E-08	7.664E-05
negative regulation of phosphorus metabolic process	GO:0010563		1.305E-07	7.501E-05
response to insulin stimulus	GO:0032868		1.964E-07	9.036E-05
negative regulation of insulin receptor signaling pathway	GO:0046627		3.168E-07	1.214E-04
induction of positive chemotaxis	GO:0050930		6.287E-07	2.066E-04
regulation of cyclin-dependent protein kinase activity	GO:0000079		6.603E-07	1.898E-04
cellular response to hormone stimulus	GO:0032870		6.761E-07	1.728E-04
regulation of insulin receptor signaling pathway	GO:0046626		1.123E-06	2.583E-04
negative regulation of protein kinase activity	GO:0006469		1.434E-06	2.999E-04

VanDeVijver file

Name	Accession Number	Link	P-val	Corrected P-val
positive regulation of protein kinase activity	GO:0045860		2.046E-08	3.77E-05
positive regulation of transferase activity	GO:0051347		2.564E-08	2.362E-05
insulin receptor signaling pathway	GO:0008286		3.468E-07	2.13E-04
regulation of cell migration	GO:0030334		7.532E-07	3.47E-04
regulation of locomotion	GO:0040012		1.724E-06	6.356E-04
regulation of cell motion	GO:0051270		1.724E-06	5.297E-04
cellular response to insulin stimulus	GO:0032869		2.234E-06	5.883E-04
activation of MAPKK activity	GO:0000186		3.845E-06	8.857E-04
response to insulin stimulus	GO:0032868		6.927E-06	1.418E-03
cellular response to hormone stimulus	GO:0032870		8.401E-06	1.548E-03
positive regulation of MAP kinase activity	GO:0043406		1.223E-05	2.048E-03

Wang file

Name	Accession Number	Link	P-val	Corrected P-val
cellular response to insulin stimulus	GO:0032869		3.534E-08	8.129E-05
negative regulation of phosphorylation	GO:0042326		7.559E-08	8.693E-05
insulin receptor signaling pathway	GO:0008286		9.996E-08	7.664E-05
negative regulation of phosphorus metabolic process	GO:0010563		1.305E-07	7.501E-05
response to insulin stimulus	GO:0032868		1.964E-07	9.036E-05
negative regulation of insulin receptor signaling pathway	GO:0046627		3.168E-07	1.214E-04
induction of positive chemotaxis	GO:0050930		6.287E-07	2.066E-04
regulation of cyclin-dependent protein kinase activity	GO:0000079		6.603E-07	1.898E-04
cellular response to hormone stimulus	GO:0032870		6.761E-07	1.728E-04
regulation of insulin receptor signaling pathway	GO:0046626		1.123E-06	2.583E-04
negative regulation of protein kinase activity	GO:0006469		1.434E-06	2.999E-04