pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6306-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! positive regulation of protein kinase activity GO:0045860 89 86 9,000 2,046E-08 3,77E-05 ! positive regulation of transferase activity GO:0051347 91 88 9,000 2,564E-08 2,362E-05 GO:0033674|positive regulation of kinase activity, ! insulin receptor signaling pathway GO:0008286 17 15 4,000 3,468E-07 2,13E-04 ! regulation of cell migration GO:0030334 71 71 7,000 7,532E-07 3,47E-04 ! regulation of locomotion GO:0040012 79 79 7,000 1,724E-06 6,356E-04 ! regulation of cell motion GO:0051270 79 79 7,000 1,724E-06 5,297E-04 ! cellular response to insulin stimulus GO:0032869 23 21 4,000 2,234E-06 5,883E-04 ! activation of MAPKK activity GO:0000186 12 11 3,000 3,845E-06 8,857E-04 ! response to insulin stimulus GO:0032868 28 26 4,000 6,927E-06 1,418E-03 ! cellular response to hormone stimulus GO:0032870 48 46 5,000 8,401E-06 1,548E-03 ! positive regulation of MAP kinase activity GO:0043406 50 49 5,000 1,223E-05 2,048E-03 ! ER overload response GO:0006983 6 6 2,000 2,335E-05 3,586E-03 ! activation of protein kinase activity GO:0032147 35 33 4,000 2,357E-05 3,341E-03 ! response to peptide hormone stimulus GO:0043434 36 34 4,000 2,74E-05 3,607E-03 ! peptidyl-amino acid modification GO:0018193 61 59 5,000 3,619E-05 4,446E-03 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 3,000 4,23E-05 4,873E-03 ! peptidyl-tyrosine modification GO:0018212 21 20 3,000 5,245E-05 5,686E-03 ! negative regulation of cellular component organization GO:0051129 65 63 5,000 5,275E-05 5,401E-03 ! protein oligomerization GO:0051259 39 39 4,000 5,438E-05 5,274E-03 ! fructose metabolic process GO:0006000 8 8 2,000 6,436E-05 5,931E-03 ! sex determination GO:0007530 8 8 2,000 6,436E-05 5,649E-03 ! regulation of MAP kinase activity GO:0043405 67 66 5,000 6,877E-05 5,761E-03 ! response to hormone stimulus GO:0009725 102 100 6,000 9,003E-05 7,214E-03 ! negative regulation of cell cycle process GO:0010948 9 9 2,000 9,58E-05 7,356E-03 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 2,000 9,58E-05 7,062E-03 ! androgen receptor signaling pathway GO:0030521 24 24 3,000 1,113E-04 7,893E-03 ! regulation of gene-specific transcription GO:0032583 25 25 3,000 1,315E-04 8,975E-03 ! cell-substrate junction assembly GO:0007044 11 10 2,000 1,358E-04 8,938E-03 ! negative regulation of cell migration GO:0030336 26 26 3,000 1,541E-04 9,795E-03 ! cell morphogenesis involved in differentiation GO:0000904 82 77 5,000 1,635E-04 0,01004193 ! regulation of DNA metabolic process GO:0051052 51 50 4,000 1,825E-04 0,01085147 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 2,000 1,853E-04 0,01067092 GO:0032388|positive regulation of intracellular transport, ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 2,000 1,853E-04 0,01034755 ! neuron projection development GO:0031175 85 80 5,000 2,02E-04 0,01094818 ! protein amino acid autophosphorylation GO:0046777 28 28 3,000 2,077E-04 0,01093551 ! MAPKKK cascade GO:0000165 82 81 5,000 2,163E-04 0,01107291 ! positive regulation of cell cycle GO:0045787 29 29 3,000 2,39E-04 0,01190232 ! blood vessel morphogenesis GO:0048514 84 83 5,000 2,473E-04 0,01199524 ! regulation of DNA replication GO:0006275 32 31 3,000 3,115E-04 0,01471817 ! negative regulation of cell motion GO:0051271 31 31 3,000 3,115E-04 0,01435021 ! vasculogenesis GO:0001570 13 13 2,000 3,162E-04 0,01421417 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 2,000 3,162E-04 0,01387574 ! response to endoplasmic reticulum stress GO:0034976 13 13 2,000 3,162E-04 0,01355305 ! protein tetramerization GO:0051262 13 13 2,000 3,162E-04 0,01324503 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 2,000 3,993E-04 0,01635559 ! response to retinoic acid GO:0032526 14 14 2,000 3,993E-04 0,01600004 GO:0033189|response to vitamin A, ! regulation of angiogenesis GO:0045765 35 34 3,000 4,48E-04 0,01756714 ! positive regulation of cellular protein metabolic process GO:0032270 61 61 4,000 4,676E-04 0,01795234 ! blood vessel development GO:0001568 95 94 5,000 4,861E-04 0,01828205 ! protein import into nucleus, translocation GO:0000060 15 15 2,000 4,953E-04 0,01825821 ! response to vitamin GO:0033273 15 15 2,000 4,953E-04 0,0179002 ! ER-nuclear signaling pathway GO:0006984 15 15 2,000 4,953E-04 0,01755597 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 3,000 5,017E-04 0,01744628 ! positive regulation of phosphorylation GO:0042327 35 35 3,000 5,017E-04 0,0171232 ! axonogenesis GO:0007409 66 62 4,000 5,044E-04 0,01690036 ! vasculature development GO:0001944 97 96 5,000 5,441E-04 0,01790787 ! positive regulation of cell migration GO:0030335 36 36 3,000 5,599E-04 0,01810217 ! positive regulation of phosphorus metabolic process GO:0010562 36 36 3,000 5,599E-04 0,01779006 GO:0045937|positive regulation of phosphate metabolic process, ! angiogenesis GO:0001525 65 64 4,000 5,844E-04 0,01825608 ! positive regulation of protein metabolic process GO:0051247 64 64 4,000 5,844E-04 0,01795182 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 2,000 6,05E-04 0,01827746 ! positive regulation of catabolic process GO:0009896 16 16 2,000 6,05E-04 0,01798266 ! posttranscriptional regulation of gene expression GO:0010608 98 98 5,000 6,075E-04 0,01777092 ! meiosis GO:0007126 37 37 3,000 6,226E-04 0,01793033 GO:0051327|M phase of meiotic cell cycle, ! meiotic cell cycle GO:0051321 38 38 3,000 6,903E-04 0,01957202 ! axon guidance GO:0007411 39 38 3,000 6,903E-04 0,01927548 ! steroid hormone receptor signaling pathway GO:0030518 38 38 3,000 6,903E-04 0,01898778 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 4,000 7,22E-04 0,01956838 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! regulation of smooth muscle cell proliferation GO:0048660 17 17 2,000 7,289E-04 0,01946971 ! cell junction assembly GO:0034329 18 17 2,000 7,289E-04 0,01919158 ! positive regulation of protein modification process GO:0031401 39 39 3,000 7,63E-04 0,01980452 ! positive regulation of cell motion GO:0051272 39 39 3,000 7,63E-04 0,01952945 ! regulation of mitotic cell cycle GO:0007346 72 69 4,000 8,263E-04 0,02086145 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 3,000 8,409E-04 0,02094239 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 2,000 8,68E-04 0,02132909 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 2,000 8,68E-04 0,02104844 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 2,000 8,68E-04 0,02077509 ! cell part morphogenesis GO:0032990 75 70 4,000 8,825E-04 0,02085169 ! regulation of protein stability GO:0031647 19 19 2,000 1,023E-03 0,02386081 ! filopodium assembly GO:0046847 7 5 1,000 1,118E-03 0,02574891 GO:0030035|microspike assembly, ! mRNA stabilization GO:0048255 5 5 1,000 1,118E-03 0,02543102 GO:0043489|RNA stabilization, ! negative regulation of endocytosis GO:0045806 5 5 1,000 1,118E-03 0,02512089 ! regulation of phospholipase A2 activity GO:0032429 5 5 1,000 1,118E-03 0,02481823 ! wound healing, spreading of epidermal cells GO:0035313 5 5 1,000 1,118E-03 0,02452277 ! protein heterooligomerization GO:0051291 5 5 1,000 1,118E-03 0,02423427 ! negative regulation of focal adhesion formation GO:0051895 6 5 1,000 1,118E-03 0,02395247 ! T cell lineage commitment GO:0002360 5 5 1,000 1,118E-03 0,02367716 ! peptidyl-lysine modification GO:0018205 5 5 1,000 1,118E-03 0,0234081 ! positive regulation of protein ubiquitination GO:0031398 5 5 1,000 1,118E-03 0,02314509 ! positive regulation of glucose metabolic process GO:0010907 5 5 1,000 1,118E-03 0,02288792 ! prostate gland development GO:0030850 5 5 1,000 1,118E-03 0,0226364 ! 2-oxoglutarate metabolic process GO:0006103 5 5 1,000 1,118E-03 0,02239036 ! memory GO:0007613 5 5 1,000 1,118E-03 0,0221496 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 1,000 1,118E-03 0,02191397 ! postreplication repair GO:0006301 5 5 1,000 1,118E-03 0,02168329 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 1,000 1,118E-03 0,02145742 ! negative regulation of neuroblast proliferation GO:0007406 5 5 1,000 1,118E-03 0,02123621 ! myeloid cell homeostasis GO:0002262 5 5 1,000 1,118E-03 0,02101952 ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 1,000 1,118E-03 0,0208072 ! negative regulation of organelle organization GO:0010639 45 44 3,000 1,209E-03 0,0222855 ! Wnt receptor signaling pathway GO:0016055 46 45 3,000 1,316E-03 0,02402215 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 2,000 1,382E-03 0,02497666 ! regulation of protein modification process GO:0031399 79 78 4,000 1,44E-03 0,02576956 ! positive regulation of DNA metabolic process GO:0051054 23 22 2,000 1,588E-03 0,02814619 ! cell junction organization GO:0034330 23 22 2,000 1,588E-03 0,02787813 ! spindle organization GO:0007051 22 22 2,000 1,588E-03 0,02761513 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 1,000 1,665E-03 0,02867622 ! N-terminal protein amino acid modification GO:0031365 6 6 1,000 1,665E-03 0,0284107 GO:0018409|peptide or protein amino-terminal blocking, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 1,000 1,665E-03 0,02815005 ! virus-host interaction GO:0019048 6 6 1,000 1,665E-03 0,02789414 ! regulation of positive chemotaxis GO:0050926 6 6 1,000 1,665E-03 0,02764284 GO:0050927|positive regulation of positive chemotaxis, ! succinate metabolic process GO:0006105 7 6 1,000 1,665E-03 0,02739603 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 1,000 1,665E-03 0,02715359 ! pathogenesis GO:0009405 6 6 1,000 1,665E-03 0,0269154 ! L-serine metabolic process GO:0006563 6 6 1,000 1,665E-03 0,02668135 ! focal adhesion formation GO:0048041 7 6 1,000 1,665E-03 0,02645134 ! negative regulation of T cell proliferation GO:0042130 6 6 1,000 1,665E-03 0,02622526 GO:0070667|negative regulation of mast cell proliferation, ! regulation of vascular permeability GO:0043114 6 6 1,000 1,665E-03 0,02600301 ! peptidyl-serine phosphorylation GO:0018105 6 6 1,000 1,665E-03 0,0257845 ! regulation of bone resorption GO:0045124 6 6 1,000 1,665E-03 0,02556963 ! G1 DNA damage checkpoint GO:0031571 6 6 1,000 1,665E-03 0,02535831 ! DNA unwinding during replication GO:0006268 6 6 1,000 1,665E-03 0,02515045 ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 1,665E-03 0,02494598 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 1,000 1,665E-03 0,0247448 ! regulation of focal adhesion formation GO:0051893 7 6 1,000 1,665E-03 0,02454684 ! serine family amino acid biosynthetic process GO:0009070 6 6 1,000 1,665E-03 0,02435203 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 1,000 1,665E-03 0,02416028 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! regulation of embryonic development GO:0045995 6 6 1,000 1,665E-03 0,02397153 ! localization within membrane GO:0051668 6 6 1,000 1,665E-03 0,0237857 ! regulation of cell cycle process GO:0010564 50 48 3,000 1,678E-03 0,02378859 ! positive regulation of growth GO:0045927 23 23 2,000 1,812E-03 0,02549942 ! cell projection assembly GO:0030031 25 23 2,000 1,812E-03 0,02530624 ! T cell differentiation GO:0030217 24 24 2,000 2,056E-03 0,02848355 ! glucan metabolic process GO:0044042 25 24 2,000 2,056E-03 0,02827098 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! interphase of mitotic cell cycle GO:0051329 52 51 3,000 2,103E-03 0,02871487 GO:0051325|interphase, ! regulation of anatomical structure morphogenesis GO:0022603 90 86 4,000 2,223E-03 0,03012522 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 1,000 2,315E-03 0,03113731 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 1,000 2,315E-03 0,03091168 ! positive regulation of cellular catabolic process GO:0031331 7 7 1,000 2,315E-03 0,03068929 ! double-strand break repair via homologous recombination GO:0000724 7 7 1,000 2,315E-03 0,03047008 GO:0000725|recombinational repair, ! SMAD protein nuclear translocation GO:0007184 7 7 1,000 2,315E-03 0,03025398 ! oxaloacetate metabolic process GO:0006107 7 7 1,000 2,315E-03 0,03004093 ! negative regulation of lipid metabolic process GO:0045833 7 7 1,000 2,315E-03 0,02983085 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 1,000 2,315E-03 0,02962369 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! cardiac muscle tissue development GO:0048738 7 7 1,000 2,315E-03 0,02941939 ! response to X-ray GO:0010165 7 7 1,000 2,315E-03 0,02921789 ! regulation of intracellular pH GO:0051453 7 7 1,000 2,315E-03 0,02901913 ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 1,000 2,315E-03 0,02882305 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! response to gamma radiation GO:0010332 8 7 1,000 2,315E-03 0,02862961 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 1,000 2,315E-03 0,02843874 GO:0001953|negative regulation of cell-matrix adhesion, ! regulation of mRNA stability GO:0043488 7 7 1,000 2,315E-03 0,02825041 ! negative regulation of T cell activation GO:0050868 7 7 1,000 2,315E-03 0,02806455 ! regulation of intracellular protein transport GO:0033157 25 25 2,000 2,318E-03 0,02792064 ! heart development GO:0007507 90 87 4,000 2,339E-03 0,02799288 ! glycolysis GO:0006096 26 26 2,000 2,6E-03 0,03091617 ! induction of apoptosis by intracellular signals GO:0008629 26 26 2,000 2,6E-03 0,03071799 ! double-strand break repair GO:0006302 27 26 2,000 2,6E-03 0,03052233 ! microtubule cytoskeleton organization GO:0000226 55 55 3,000 2,779E-03 0,03241918 ! negative regulation of cell cycle GO:0045786 92 91 4,000 2,848E-03 0,0330091 ! DNA replication GO:0006260 91 91 4,000 2,848E-03 0,03280279 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 2,000 2,903E-03 0,03322773 ! energy reserve metabolic process GO:0006112 28 27 2,000 2,903E-03 0,03302262 ! learning or memory GO:0007611 28 27 2,000 2,903E-03 0,03282003 ! reproductive developmental process GO:0003006 56 56 3,000 2,969E-03 0,03336509 ! negative regulation of bone remodeling GO:0046851 8 8 1,000 3,065E-03 0,03423157 ! embryonic hindlimb morphogenesis GO:0035116 8 8 1,000 3,065E-03 0,03402535 ! zinc ion transport GO:0006829 8 8 1,000 3,065E-03 0,03382161 ! embryonic forelimb morphogenesis GO:0035115 8 8 1,000 3,065E-03 0,03362029 ! DNA duplex unwinding GO:0032508 8 8 1,000 3,065E-03 0,03342135 GO:0032392|DNA geometric change, ! phosphagen metabolic process GO:0006599 8 8 1,000 3,065E-03 0,03322476 GO:0006600|creatine metabolic process, ! positive regulation of endothelial cell migration GO:0010595 8 8 1,000 3,065E-03 0,03303046 ! plasma membrane fusion GO:0045026 8 8 1,000 3,065E-03 0,03283842 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 1,000 3,065E-03 0,03264861 ! regulation of fatty acid metabolic process GO:0019217 8 8 1,000 3,065E-03 0,03246097 ! peptidyl-serine modification GO:0018209 8 8 1,000 3,065E-03 0,03227548 ! positive regulation of leukocyte migration GO:0002687 8 8 1,000 3,065E-03 0,03209209 ! branched chain family amino acid metabolic process GO:0009081 8 8 1,000 3,065E-03 0,03191078 ! regulation of RNA stability GO:0043487 8 8 1,000 3,065E-03 0,03173151 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 1,000 3,065E-03 0,03155424 ! release of cytochrome c from mitochondria GO:0001836 9 8 1,000 3,065E-03 0,03137894 ! regulation of epithelial cell proliferation GO:0050678 29 29 2,000 3,571E-03 0,03635869 ! DNA-dependent DNA replication GO:0006261 29 29 2,000 3,571E-03 0,03615892 ! regulation of gene expression, epigenetic GO:0040029 29 29 2,000 3,571E-03 0,03596133 ! positive regulation of protein transport GO:0051222 29 29 2,000 3,571E-03 0,03576588 ! response to UV GO:0009411 29 29 2,000 3,571E-03 0,03557255 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 1,000 3,913E-03 0,03877171 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 1,000 3,913E-03 0,03856438 ! positive regulation of endothelial cell proliferation GO:0001938 9 9 1,000 3,913E-03 0,03835925 ! pigmentation during development GO:0048066 9 9 1,000 3,913E-03 0,03815629 ! positive regulation of protein import into nucleus GO:0042307 9 9 1,000 3,913E-03 0,03795546 ! DNA replication initiation GO:0006270 9 9 1,000 3,913E-03 0,03775674 ! regulation of cellular pH GO:0030641 9 9 1,000 3,913E-03 0,03756009 ! histone acetylation GO:0016573 9 9 1,000 3,913E-03 0,03736548 ! negative regulation of tissue remodeling GO:0034104 9 9 1,000 3,913E-03 0,03717288 ! regulation of leukocyte migration GO:0002685 9 9 1,000 3,913E-03 0,03698225 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 1,000 3,913E-03 0,03679356 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 2,000 3,937E-03 0,03683317 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 3,000 4,052E-03 0,03771272 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 4,000 4,279E-03 0,03962767 ! negative regulation of cytoskeleton organization GO:0051494 32 31 2,000 4,326E-03 0,03986038 ! regulation of intracellular transport GO:0032386 31 31 2,000 4,326E-03 0,03966207 ! glucose catabolic process GO:0006007 32 32 2,000 4,737E-03 0,04321514 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 2,000 4,737E-03 0,04300226 ! regulation of protein ubiquitination GO:0031396 10 10 1,000 4,857E-03 0,04388164 ! regulation of glucose metabolic process GO:0010906 10 10 1,000 4,857E-03 0,04366758 ! regulation of lipid biosynthetic process GO:0046890 10 10 1,000 4,857E-03 0,0434556 ! inositol metabolic process GO:0006020 10 10 1,000 4,857E-03 0,04324567 ! forelimb morphogenesis GO:0035136 10 10 1,000 4,857E-03 0,04303776 ! apoptotic mitochondrial changes GO:0008637 11 10 1,000 4,857E-03 0,04283184 ! centrosome cycle GO:0007098 10 10 1,000 4,857E-03 0,04262788 ! positive regulation of proteolysis GO:0045862 10 10 1,000 4,857E-03 0,04242585 ! plasma membrane organization GO:0007009 10 10 1,000 4,857E-03 0,04222573 ! neuromuscular junction development GO:0007528 10 10 1,000 4,857E-03 0,04202749 ! epithelial to mesenchymal transition GO:0001837 10 10 1,000 4,857E-03 0,0418311 ! positive regulation of neuron apoptosis GO:0043525 10 10 1,000 4,857E-03 0,04163653 ! negative regulation of homeostatic process GO:0032845 10 10 1,000 4,857E-03 0,04144377 ! cellular polysaccharide metabolic process GO:0044264 35 34 2,000 5,627E-03 0,04779361 ! striated muscle tissue development GO:0014706 69 67 3,000 5,67E-03 0,04793473 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 1,000 5,895E-03 0,04961312 ! G1 phase of mitotic cell cycle GO:0000080 12 11 1,000 5,895E-03 0,04938761 ! endothelial cell migration GO:0043542 11 11 1,000 5,895E-03 0,04916413 ! protein amino acid acetylation GO:0006473 11 11 1,000 5,895E-03 0,04894267 ! cellular response to starvation GO:0009267 11 11 1,000 5,895E-03 0,0487232 ! regulation of cellular ketone metabolic process GO:0010565 11 11 1,000 5,895E-03 0,04850568 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 1,000 5,895E-03 0,0482901 ! G1/S transition checkpoint GO:0031575 12 11 1,000 5,895E-03 0,04807643 ! interaction with host GO:0051701 11 11 1,000 5,895E-03 0,04786464 ! regulation of monooxygenase activity GO:0032768 11 11 1,000 5,895E-03 0,04765471 ! negative regulation of angiogenesis GO:0016525 11 11 1,000 5,895E-03 0,04744661 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 1,000 5,895E-03 0,04724032 GO:0006109|regulation of carbohydrate metabolic process, ! muscle maintenance GO:0046716 12 11 1,000 5,895E-03 0,04703582 ! negative regulation of lymphocyte activation GO:0051250 11 11 1,000 5,895E-03 0,04683307 ! response to radiation GO:0009314 70 68 3,000 5,976E-03 0,04726979 ! mesoderm development GO:0007498 35 35 2,000 6,108E-03 0,04810611 ! response to nutrient levels GO:0031667 69 69 3,000 6,293E-03 0,04935285 ! regulation of mitosis GO:0007088 37 36 2,000 6,612E-03 0,05163718 GO:0051783|regulation of nuclear division, ! wound healing GO:0042060 74 70 3,000 6,621E-03 0,0514863 ! muscle tissue development GO:0060537 72 70 3,000 6,621E-03 0,05126997 ! translational elongation GO:0006414 71 71 3,000 6,96E-03 0,05367011 ! negative regulation of signal transduction GO:0009968 71 71 3,000 6,96E-03 0,05344648 ! positive regulation of protein catabolic process GO:0045732 12 12 1,000 7,025E-03 0,05372603 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 1,000 7,025E-03 0,05350402 ! heterophilic cell adhesion GO:0007157 12 12 1,000 7,025E-03 0,05328384 ! hindlimb morphogenesis GO:0035137 12 12 1,000 7,025E-03 0,05306546 ! microtubule organizing center organization GO:0031023 12 12 1,000 7,025E-03 0,05284887 GO:0051297|centrosome organization, ! barbed-end actin filament capping GO:0051016 12 12 1,000 7,025E-03 0,05263403 GO:0051693|actin filament capping, ! regulation of chromosome organization GO:0033044 12 12 1,000 7,025E-03 0,05242094 ! positive regulation of multicellular organism growth GO:0040018 12 12 1,000 7,025E-03 0,05220957 ! somitogenesis GO:0001756 13 12 1,000 7,025E-03 0,05199989 ! G1 phase GO:0051318 13 12 1,000 7,025E-03 0,05179189 ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 1,000 7,025E-03 0,05158555 ! negative regulation of translation GO:0017148 12 12 1,000 7,025E-03 0,05138084 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 1,000 7,025E-03 0,05117776 ! negative regulation of protein kinase activity GO:0006469 37 37 2,000 7,141E-03 0,05181256 ! response to drug GO:0042493 37 37 2,000 7,141E-03 0,05160937 ! lung development GO:0030324 38 37 2,000 7,141E-03 0,05140777 ! DNA damage response, signal transduction GO:0042770 37 37 2,000 7,141E-03 0,05120774 ! response to extracellular stimulus GO:0009991 72 72 3,000 7,31E-03 0,05222062 ! negative regulation of kinase activity GO:0033673 38 38 2,000 7,694E-03 0,05474664 ! cell-matrix adhesion GO:0007160 39 38 2,000 7,694E-03 0,05453607 ! chromosome segregation GO:0007059 38 38 2,000 7,694E-03 0,05432712 ! urogenital system development GO:0001655 38 38 2,000 7,694E-03 0,05411977 ! hexose catabolic process GO:0019320 38 38 2,000 7,694E-03 0,05391399 ! positive regulation of DNA replication GO:0045740 14 13 1,000 8,245E-03 0,05756132 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 1,000 8,245E-03 0,05734411 ! negative regulation of actin filament polymerization GO:0030837 13 13 1,000 8,245E-03 0,05712853 ! G2/M transition of mitotic cell cycle GO:0000086 13 13 1,000 8,245E-03 0,05691456 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 1,000 8,245E-03 0,0567022 ! post-embryonic development GO:0009791 14 13 1,000 8,245E-03 0,05649141 ! mitochondrial membrane organization GO:0007006 13 13 1,000 8,245E-03 0,05628218 ! negative regulation of DNA replication GO:0008156 13 13 1,000 8,245E-03 0,0560745 ! actin filament bundle formation GO:0051017 13 13 1,000 8,245E-03 0,05586834 ! cell aging GO:0007569 13 13 1,000 8,245E-03 0,0556637 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 1,000 8,245E-03 0,05546054 ! regulation of endothelial cell migration GO:0010594 13 13 1,000 8,245E-03 0,05525887 ! negative regulation of protein kinase cascade GO:0010741 13 13 1,000 8,245E-03 0,05505866 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 1,000 8,245E-03 0,05485989 ! positive regulation of locomotion GO:0040017 13 13 1,000 8,245E-03 0,05466255 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! negative regulation of leukocyte activation GO:0002695 13 13 1,000 8,245E-03 0,05446663 ! regulation of cell-substrate adhesion GO:0010810 14 13 1,000 8,245E-03 0,0542721 GO:0001952|regulation of cell-matrix adhesion, ! hemostasis GO:0007599 42 39 2,000 8,271E-03 0,05424846 ! activation of MAPK activity GO:0000187 39 39 2,000 8,271E-03 0,05405609 ! respiratory tube development GO:0030323 40 39 2,000 8,271E-03 0,05386508 ! nucleotide-excision repair GO:0006289 40 39 2,000 8,271E-03 0,05367541 ! respiratory system development GO:0060541 40 39 2,000 8,271E-03 0,05348708 ! lymphocyte differentiation GO:0030098 39 39 2,000 8,271E-03 0,05330006 ! negative regulation of cell communication GO:0010648 76 76 3,000 8,828E-03 0,05669075 ! negative regulation of transferase activity GO:0051348 40 40 2,000 8,874E-03 0,05678524 ! cell cycle checkpoint GO:0000075 42 41 2,000 9,501E-03 0,06059096 ! regulation of caspase activity GO:0043281 41 41 2,000 9,501E-03 0,06038202 ! monosaccharide catabolic process GO:0046365 41 41 2,000 9,501E-03 0,06017452 ! protein amino acid acylation GO:0043543 14 14 1,000 9,553E-03 0,06029527 ! regulation of behavior GO:0050795 14 14 1,000 9,553E-03 0,06008949 ! base-excision repair GO:0006284 14 14 1,000 9,553E-03 0,0598851 ! negative regulation of protein polymerization GO:0032272 14 14 1,000 9,553E-03 0,0596821 ! regulation of endopeptidase activity GO:0052548 42 42 2,000 0,01015416 0,06322336 ! cell-substrate adhesion GO:0031589 43 42 2,000 0,01015416 0,06301049 ! forebrain development GO:0030900 43 42 2,000 0,01015416 0,06279904 ! reproductive structure development GO:0048608 43 43 2,000 0,0108326 0,06677087 ! alcohol catabolic process GO:0046164 43 43 2,000 0,0108326 0,0665483 ! response to starvation GO:0042594 15 15 1,000 0,01094651 0,06702466 ! leukocyte homeostasis GO:0001776 15 15 1,000 0,01094651 0,06680272 ! negative regulation of actin filament depolymerization GO:0030835 15 15 1,000 0,01094651 0,06658225 ! negative regulation of protein complex assembly GO:0031333 15 15 1,000 0,01094651 0,06636323 ! regulation of transcription factor import into nucleus GO:0042990 15 15 1,000 0,01094651 0,06614564 ! response to ionizing radiation GO:0010212 16 15 1,000 0,01094651 0,06592948 ! negative regulation of cell activation GO:0050866 15 15 1,000 0,01094651 0,06571473 ! protein homooligomerization GO:0051260 15 15 1,000 0,01094651 0,06550137 ! protein import into nucleus GO:0006606 44 44 2,000 0,01153676 0,06880985 ! nuclear import GO:0051170 45 45 2,000 0,01226678 0,07292797 ! phosphoinositide-mediated signaling GO:0048015 45 45 2,000 0,01226678 0,07269348 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 1,000 0,01242388 0,07338848 ! positive regulation of mitosis GO:0045840 16 16 1,000 0,01242388 0,07315401 GO:0051785|positive regulation of nuclear division, ! segmentation GO:0035282 17 16 1,000 0,01242388 0,07292104 ! cellular response to nutrient levels GO:0031669 16 16 1,000 0,01242388 0,07268954 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 1,000 0,01242388 0,07245951 ! polyol metabolic process GO:0019751 16 16 1,000 0,01242388 0,07223094 ! serine family amino acid metabolic process GO:0009069 16 16 1,000 0,01242388 0,07200379 ! regulation of peptidase activity GO:0052547 46 46 2,000 0,01302282 0,07523841 ! sex differentiation GO:0007548 47 47 2,000 0,01380501 0,07950823 ! regulation of catabolic process GO:0009894 48 47 2,000 0,01380501 0,07926054 ! regulation of fibroblast proliferation GO:0048145 17 17 1,000 0,0139832 0,0800343 ! regulation of actin filament depolymerization GO:0030834 17 17 1,000 0,0139832 0,07978652 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 0,0139832 0,07954027 ! myelination GO:0042552 17 17 1,000 0,0139832 0,07929553 ! leukocyte adhesion GO:0007159 17 17 1,000 0,0139832 0,07905229 ! dicarboxylic acid metabolic process GO:0043648 18 17 1,000 0,0139832 0,07881054 ! glucose transport GO:0015758 17 17 1,000 0,0139832 0,07857026 ! tissue remodeling GO:0048771 17 17 1,000 0,0139832 0,07833145 ! response to toxin GO:0009636 18 17 1,000 0,0139832 0,07809408 ! negative regulation of cell development GO:0010721 18 17 1,000 0,0139832 0,07785815 GO:0050768|negative regulation of neurogenesis, ! regulation of oxidoreductase activity GO:0051341 17 17 1,000 0,0139832 0,07762363 ! pigmentation GO:0043473 17 17 1,000 0,0139832 0,07739053 ! protein localization in nucleus GO:0034504 48 48 2,000 0,01461348 0,08063665 ! leukocyte differentiation GO:0002521 50 49 2,000 0,01544833 0,08498888 ! gland development GO:0048732 51 49 2,000 0,01544833 0,08473594 ! skeletal muscle tissue development GO:0007519 50 49 2,000 0,01544833 0,0844845 GO:0060538|skeletal muscle organ development, ! response to nutrient GO:0007584 49 49 2,000 0,01544833 0,08423454 ! regulation of cellular catabolic process GO:0031329 18 18 1,000 0,01562261 0,08493353 ! meiosis I GO:0007127 18 18 1,000 0,01562261 0,08468373 ! hexose transport GO:0008645 18 18 1,000 0,01562261 0,08443539 GO:0015749|monosaccharide transport, ! B cell differentiation GO:0030183 18 18 1,000 0,01562261 0,0841885 ! cellular response to extracellular stimulus GO:0031668 18 18 1,000 0,01562261 0,08394305 ! ensheathment of neurons GO:0007272 18 18 1,000 0,01562261 0,08369903 GO:0008366|axon ensheathment, ! regulation of microtubule-based process GO:0032886 18 18 1,000 0,01562261 0,08345643 ! T cell activation GO:0042110 51 50 2,000 0,01630966 0,08687488 ! rRNA metabolic process GO:0016072 51 51 2,000 0,01719756 0,09134034 GO:0006364|rRNA processing, ! DNA damage checkpoint GO:0000077 19 19 1,000 0,01734023 0,09183348 ! negative regulation of DNA metabolic process GO:0051053 19 19 1,000 0,01734023 0,09157035 ! regulation of pH GO:0006885 19 19 1,000 0,01734023 0,09130872 ! regulation of JAK-STAT cascade GO:0046425 19 19 1,000 0,01734023 0,09104858 ! regulation of endothelial cell proliferation GO:0001936 19 19 1,000 0,01734023 0,09078992 ! multicellular organismal metabolic process GO:0044236 19 19 1,000 0,01734023 0,09053272 ! peripheral nervous system development GO:0007422 19 19 1,000 0,01734023 0,09027698 ! regulation of cell shape GO:0008360 21 19 1,000 0,01734023 0,09002268 ! regulation of body fluid levels GO:0050878 55 52 2,000 0,01811208 0,09376564 ! response to light stimulus GO:0009416 53 52 2,000 0,01811208 0,09350299 ! carbohydrate catabolic process GO:0016052 53 53 2,000 0,0190533 0,09808724 ! regulation of protein transport GO:0051223 53 53 2,000 0,0190533 0,09781401 GO:0070201|regulation of establishment of protein localization, ! response to hypoxia GO:0001666 53 53 2,000 0,0190533 0,09754231 ! negative regulation of cell adhesion GO:0007162 21 20 1,000 0,01913426 0,09768541 ! positive regulation of gene-specific transcription GO:0043193 20 20 1,000 0,01913426 0,09741557 ! protein amino acid dephosphorylation GO:0006470 55 54 2,000 0,02002125 0,10165061 ! response to oxygen levels GO:0070482 55 54 2,000 0,02002125 0,10137135 ! mitotic sister chromatid segregation GO:0000070 21 21 1,000 0,02100288 0,10605016 ! mammary gland development GO:0030879 23 21 1,000 0,02100288 0,10576041 ! Notch signaling pathway GO:0007219 22 21 1,000 0,02100288 0,10547223 ! DNA integrity checkpoint GO:0031570 21 21 1,000 0,02100288 0,10518563 ! regulation of protein import into nucleus GO:0042306 21 21 1,000 0,02100288 0,10490057 ! regulation of action potential in neuron GO:0019228 21 21 1,000 0,02100288 0,10461705 ! regulation of multicellular organism growth GO:0040014 21 21 1,000 0,02100288 0,10433507 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 1,000 0,02100288 0,1040546 ! regulation of proteolysis GO:0030162 21 21 1,000 0,02100288 0,10377563 ! negative regulation of hydrolase activity GO:0051346 21 21 1,000 0,02100288 0,10349816 ! in utero embryonic development GO:0001701 55 55 2,000 0,02101598 0,10328655 ! regulation of cell adhesion GO:0030155 56 55 2,000 0,02101598 0,10301186 ! muscle organ development GO:0007517 102 100 3,000 0,02226695 0,10885409 ! hemopoiesis GO:0030097 104 100 3,000 0,02226695 0,10856612 ! positive regulation of transcription factor activity GO:0051091 22 22 1,000 0,02294434 0,11157367 GO:0090047|positive regulation of transcription regulator activity, ! sister chromatid segregation GO:0000819 22 22 1,000 0,02294434 0,11128005 ! cellular amide metabolic process GO:0043603 22 22 1,000 0,02294434 0,11098798 ! male sex differentiation GO:0046661 22 22 1,000 0,02294434 0,11069744 ! neuron migration GO:0001764 22 22 1,000 0,02294434 0,11040841 ! cytokinesis GO:0000910 23 22 1,000 0,02294434 0,11012089 ! regulation of protein localization GO:0032880 58 57 2,000 0,02308585 0,11051226 ! response to estrogen stimulus GO:0043627 23 23 1,000 0,0249569 0,11915949 ! negative regulation of protein complex disassembly GO:0043242 23 23 1,000 0,0249569 0,11885159 ! mitotic cell cycle checkpoint GO:0007093 24 23 1,000 0,0249569 0,11854527 ! monovalent inorganic cation homeostasis GO:0055067 23 23 1,000 0,0249569 0,11824052 ! calcium-mediated signaling GO:0019722 23 23 1,000 0,0249569 0,11793734 ! dephosphorylation GO:0016311 60 59 2,000 0,02526297 0,11907839 ! protein localization in organelle GO:0033365 59 59 2,000 0,02526297 0,11877462 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 2,000 0,02639173 0,12376578 ! mitochondrial transport GO:0006839 24 24 1,000 0,02703884 0,12647865 ! regulation of action potential GO:0001508 24 24 1,000 0,02703884 0,12615845 ! cellular amino acid biosynthetic process GO:0008652 24 24 1,000 0,02703884 0,12583986 ! glucose homeostasis GO:0042593 24 24 1,000 0,02703884 0,12552289 GO:0033500|carbohydrate homeostasis, ! regulation of cellular component biogenesis GO:0044087 63 62 2,000 0,0287295 0,13303637 ! protein import GO:0017038 62 62 2,000 0,0287295 0,13270294 ! regulation of actin filament polymerization GO:0030833 25 25 1,000 0,02918849 0,13448597 ! regulation of T cell proliferation GO:0042129 25 25 1,000 0,02918849 0,1341506 ! positive regulation of DNA binding GO:0043388 26 25 1,000 0,02918849 0,13381689 ! heart morphogenesis GO:0003007 25 25 1,000 0,02918849 0,13348484 ! regulation of endocytosis GO:0030100 25 25 1,000 0,02918849 0,13315443 ! negative regulation of immune system process GO:0002683 25 25 1,000 0,02918849 0,13282565 ! JAK-STAT cascade GO:0007259 26 25 1,000 0,02918849 0,13249849 ! glucose metabolic process GO:0006006 63 63 2,000 0,02993844 0,13556893 ! regulation of cytoskeleton organization GO:0051493 66 64 2,000 0,03117402 0,14081793 ! positive regulation of binding GO:0051099 27 26 1,000 0,03140419 0,14151081 ! regulation of T cell differentiation GO:0045580 26 26 1,000 0,03140419 0,14116566 ! synapse organization GO:0050808 26 26 1,000 0,03140419 0,14082219 ! activation of caspase activity GO:0006919 27 27 1,000 0,03368431 0,15068005 ! mesenchymal cell development GO:0014031 29 27 1,000 0,03368431 0,15031521 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! cell growth GO:0016049 27 27 1,000 0,03368431 0,14995213 ! polysaccharide metabolic process GO:0005976 69 66 2,000 0,03372481 0,14977067 ! negative regulation of protein metabolic process GO:0051248 66 66 2,000 0,03372481 0,14941064 ! stress-activated protein kinase signaling pathway GO:0031098 28 28 1,000 0,03602725 0,15922834 GO:0007254|JNK cascade, ! carbohydrate transport GO:0008643 28 28 1,000 0,03602725 0,15884741 ! histone modification GO:0016570 28 28 1,000 0,03602725 0,1584683 ! regulation of mast cell proliferation GO:0070666 28 28 1,000 0,03602725 0,158091 ! regulation of cell size GO:0008361 68 68 2,000 0,03638129 0,15926536 ! regulation of translation GO:0006417 69 69 2,000 0,03774894 0,16486089 ! viral reproductive process GO:0022415 29 29 1,000 0,03843143 0,16744475 ! phosphoinositide metabolic process GO:0030384 29 29 1,000 0,03843143 0,16704983 ! regulation of lymphocyte proliferation GO:0050670 29 29 1,000 0,03843143 0,16665678 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! covalent chromatin modification GO:0016569 29 29 1,000 0,03843143 0,16626556 ! regulation of protein polymerization GO:0032271 29 29 1,000 0,03843143 0,16587618 ! positive regulation of transport GO:0051050 71 70 2,000 0,03914273 0,16855154 ! ribosome biogenesis GO:0042254 71 71 2,000 0,04056256 0,17425829 ! activation of phospholipase C activity GO:0007202 30 30 1,000 0,04089531 0,1752792 GO:0010863|positive regulation of phospholipase C activity, ! transition metal ion transport GO:0000041 31 30 1,000 0,04089531 0,17487252 ! positive regulation of peptidase activity GO:0010952 30 30 1,000 0,04089531 0,17446773 GO:0043280|positive regulation of caspase activity, ! regulation of protein complex disassembly GO:0043244 30 30 1,000 0,04089531 0,1740648 ! positive regulation of response to external stimulus GO:0032103 30 30 1,000 0,04089531 0,17366373 ! vascular process in circulatory system GO:0003018 31 30 1,000 0,04089531 0,1732645 ! establishment of organelle localization GO:0051656 31 30 1,000 0,04089531 0,1728671 ! positive regulation of hydrolase activity GO:0051345 72 72 2,000 0,04200831 0,1771655 ! regulation of translational initiation GO:0006446 31 31 1,000 0,04341736 0,18268994 ! skeletal muscle fiber development GO:0048741 31 31 1,000 0,04341736 0,18227379 ! membrane fusion GO:0006944 31 31 1,000 0,04341736 0,18185953 ! B cell activation GO:0042113 31 31 1,000 0,04341736 0,18144715 ! positive regulation of phospholipase activity GO:0010518 31 31 1,000 0,04341736 0,18103664 ! aging GO:0007568 32 31 1,000 0,04341736 0,18062798 ! negative regulation of cell growth GO:0030308 32 32 1,000 0,04599608 0,19092517 ! muscle fiber development GO:0048747 32 32 1,000 0,04599608 0,19049613 ! lipid modification GO:0030258 32 32 1,000 0,04599608 0,19006901 ! regulation of phospholipase activity GO:0010517 32 32 1,000 0,04599608 0,1896438 ! regulation of vesicle-mediated transport GO:0060627 33 32 1,000 0,04599608 0,18922048 ! regulation of lymphocyte differentiation GO:0045619 32 32 1,000 0,04599608 0,18879906 ! positive regulation of lipase activity GO:0060193 32 32 1,000 0,04599608 0,1883795 ! negative regulation of cell size GO:0045792 33 33 1,000 0,04863 0,19872525 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 1,000 0,04863 0,19828559 ! regulation of cellular response to stress GO:0080135 35 33 1,000 0,04863 0,19784788 ! amino acid transport GO:0006865 33 33 1,000 0,04863 0,19741209 ! regulation of protein complex assembly GO:0043254 33 33 1,000 0,04863 0,19697821 ! regulation of neuron apoptosis GO:0043523 34 33 1,000 0,04863 0,19654624 ! regulation of actin filament length GO:0030832 34 34 1,000 0,05131766 0,20695504 ! regulation of bone remodeling GO:0046850 34 34 1,000 0,05131766 0,20650318 ! regulation of protein catabolic process GO:0042176 35 34 1,000 0,05131766 0,20605328 ! regulation of lipid metabolic process GO:0019216 34 34 1,000 0,05131766 0,20560534 ! secondary metabolic process GO:0019748 34 34 1,000 0,05131766 0,20515934 ! viral reproduction GO:0016032 34 34 1,000 0,05131766 0,20471527 ! rRNA transcription GO:0009303 5 5 0,000 0,05264955 0,20957477 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,05264955 0,2091231 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,05264955 0,20867337 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,05264955 0,20822558 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,05264955 0,2077797 ! reproductive cellular process GO:0048610 5 5 0,000 0,05264955 0,20733572 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,05264955 0,20689364 ! metencephalon development GO:0022037 5 5 0,000 0,05264955 0,20645344 ! water transport GO:0006833 5 5 0,000 0,05264955 0,20601511 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,05264955 0,20557864 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,05264955 0,20514401 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,05264955 0,20471122 ! glycerol metabolic process GO:0006071 5 5 0,000 0,05264955 0,20428025 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,05264955 0,20385109 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,05264955 0,20342373 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,05264955 0,20299816 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,05264955 0,20257436 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,05264955 0,20215233 ! CTP metabolic process GO:0046036 5 5 0,000 0,05264955 0,20173206 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,05264955 0,20131352 ! GTP metabolic process GO:0046039 5 5 0,000 0,05264955 0,20089673 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,05264955 0,20048165 ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,05264955 0,20006829 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,05264955 0,19965662 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,05264955 0,19924665 ! social behavior GO:0035176 5 5 0,000 0,05264955 0,19883836 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,05264955 0,19843174 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 0,05264955 0,19802677 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,05264955 0,19762346 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,05264955 0,19722179 ! response to lipid GO:0033993 5 5 0,000 0,05264955 0,19682174 ! erythrocyte maturation GO:0043249 5 5 0,000 0,05264955 0,19642332 ! hippocampus development GO:0021766 6 5 0,000 0,05264955 0,1960265 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,05264955 0,19563129 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,05264955 0,19523766 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,05264955 0,19484562 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,05264955 0,19445515 ! mechanosensory behavior GO:0007638 5 5 0,000 0,05264955 0,19406624 ! heart looping GO:0001947 5 5 0,000 0,05264955 0,19367888 ! response to interferon-gamma GO:0034341 5 5 0,000 0,05264955 0,19329306 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,05264955 0,19290878 ! endocrine pancreas development GO:0031018 5 5 0,000 0,05264955 0,19252603 ! pH reduction GO:0045851 5 5 0,000 0,05264955 0,19214479 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,05264955 0,19176506 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,05264955 0,19138682 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,05264955 0,19101008 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,05264955 0,19063481 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,05264955 0,19026102 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,05264955 0,18988869 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,05264955 0,18951781 ! adrenal gland development GO:0030325 5 5 0,000 0,05264955 0,18914838 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,05264955 0,18878039 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,05264955 0,18841382 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,05264955 0,18804868 ! astrocyte differentiation GO:0048708 5 5 0,000 0,05264955 0,18768495 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,05264955 0,18732262 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,05264955 0,18696169 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,05264955 0,18660215 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,05264955 0,18624399 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,05264955 0,1858872 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,05264955 0,18553178 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,05264955 0,18517771 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,05264955 0,18482499 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,05264955 0,18447361 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,05264955 0,18412356 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,05264955 0,18377485 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,05264955 0,18342745 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,05264955 0,18308136 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,05264955 0,18273657 ! response to ATP GO:0033198 5 5 0,000 0,05264955 0,18239308 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,05264955 0,18205088 ! regulation of appetite GO:0032098 5 5 0,000 0,05264955 0,18170996 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,05264955 0,18137032 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,05264955 0,18103194 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,05264955 0,18069482 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,05264955 0,18035896 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,05264955 0,18002434 ! receptor clustering GO:0043113 5 5 0,000 0,05264955 0,17969096 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,05264955 0,17935881 ! fear response GO:0042596 5 5 0,000 0,05264955 0,17902789 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 0,05264955 0,17869819 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,05264955 0,1783697 ! retinol metabolic process GO:0042572 5 5 0,000 0,05264955 0,17804242 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,05264955 0,17771633 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,05264955 0,17739144 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,05264955 0,17706773 ! parturition GO:0007567 5 5 0,000 0,05264955 0,17674521 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,05264955 0,17642385 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,05264955 0,17610366 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,05264955 0,17578464 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,05264955 0,17546676 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,05264955 0,17515003 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,05264955 0,17483445 ! response to UV-B GO:0010224 5 5 0,000 0,05264955 0,17452 ! oligodendrocyte development GO:0014003 5 5 0,000 0,05264955 0,17420668 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,05264955 0,17389448 ! activated T cell proliferation GO:0050798 5 5 0,000 0,05264955 0,1735834 ! interaction with symbiont GO:0051702 5 5 0,000 0,05264955 0,17327343 ! cellular extravasation GO:0045123 5 5 0,000 0,05264955 0,17296456 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,05264955 0,17265679 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,05264955 0,17235012 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,05264955 0,17204454 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,05264955 0,17174003 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,05264955 0,17143661 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,05264955 0,17113425 ! response to amine stimulus GO:0014075 5 5 0,000 0,05264955 0,17083296 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,05264955 0,17053272 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,05264955 0,17023354 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,05264955 0,16993541 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,05264955 0,16963832 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,05264955 0,16934227 ! neuron recognition GO:0008038 5 5 0,000 0,05264955 0,16904724 ! decidualization GO:0046697 5 5 0,000 0,05264955 0,16875325 ! hair follicle maturation GO:0048820 5 5 0,000 0,05264955 0,16846028 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,05264955 0,16816832 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,05264955 0,16787737 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,05264955 0,16758742 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,05264955 0,16729848 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,05264955 0,16701053 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,05264955 0,16672357 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,05264955 0,1664376 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 0,05264955 0,1661526 ! histone methylation GO:0016571 5 5 0,000 0,05264955 0,16586858 ! DNA methylation GO:0006306 5 5 0,000 0,05264955 0,16558553 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,05264955 0,16530344 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,05264955 0,16502231 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,05264955 0,16474214 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,05264955 0,16446291 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,05264955 0,16418463 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,05264955 0,16390729 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,05264955 0,16363089 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,05264955 0,16335542 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,05264955 0,16308087 ! sterol catabolic process GO:0016127 5 5 0,000 0,05264955 0,16280725 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,05264955 0,16253454 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,05264955 0,16226274 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,05264955 0,16199185 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,05264955 0,16172186 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,05264955 0,16145278 ! zymogen activation GO:0031638 5 5 0,000 0,05264955 0,16118458 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,05264955 0,16091728 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,05264955 0,16065086 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,05264955 0,16038532 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,05264955 0,16012066 ! nucleosome positioning GO:0016584 5 5 0,000 0,05264955 0,15985687 ! regulation of isotype switching GO:0045191 5 5 0,000 0,05264955 0,15959394 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,05264955 0,15933189 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,05264955 0,15907069 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,05264955 0,15881034 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,05264955 0,15855085 ! NADPH regeneration GO:0006740 5 5 0,000 0,05264955 0,1582922 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,05264955 0,1580344 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,05264955 0,15777743 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,05264955 0,1575213 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,05264955 0,15726599 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,05264955 0,15701152 ! sarcomere organization GO:0045214 5 5 0,000 0,05264955 0,15675787 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,05264955 0,15650503 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,05264955 0,15625301 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,05264955 0,1560018 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,05264955 0,15575139 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 0,05264955 0,15550179 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,05264955 0,15525299 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,05264955 0,15500498 ! spleen development GO:0048536 5 5 0,000 0,05264955 0,15475776 ! male genitalia development GO:0030539 5 5 0,000 0,05264955 0,15451134 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,05264955 0,15426569 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,05264955 0,15402082 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,05264955 0,15377673 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,05264955 0,15353342 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,05264955 0,15329087 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,05264955 0,15304908 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,05264955 0,15280806 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,05264955 0,1525678 ! ATP catabolic process GO:0006200 5 5 0,000 0,05264955 0,15232829 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,05264955 0,15208953 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,05264955 0,15185152 ! blastocyst formation GO:0001825 5 5 0,000 0,05264955 0,15161425 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,05264955 0,15137772 ! embryonic gut development GO:0048566 5 5 0,000 0,05264955 0,15114193 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,05264955 0,15090687 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,05264955 0,15067254 ! activation of innate immune response GO:0002218 5 5 0,000 0,05264955 0,15043894 GO:0002758|innate immune response-activating signal transduction, ! catecholamine transport GO:0051937 5 5 0,000 0,05264955 0,15020607 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,05264955 0,14997391 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,05264955 0,14974247 ! muscle adaptation GO:0043500 5 5 0,000 0,05264955 0,14951174 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,05264955 0,14928172 ! embryonic heart tube development GO:0035050 5 5 0,000 0,05264955 0,14905241 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,05264955 0,1488238 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,05264955 0,14859589 ! defense response to fungus GO:0050832 5 5 0,000 0,05264955 0,14836868 ! lysogeny GO:0030069 5 5 0,000 0,05264955 0,14814217 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,05264955 0,14791634 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,05264955 0,1476912 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,05264955 0,14746675 ! response to nicotine GO:0035094 5 5 0,000 0,05264955 0,14724297 ! establishment of cell polarity GO:0030010 5 5 0,000 0,05264955 0,14701988 ! mitochondrion localization GO:0051646 5 5 0,000 0,05264955 0,14679746 ! nucleus localization GO:0051647 5 5 0,000 0,05264955 0,14657571 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,05264955 0,14635463 ! nuclear transport GO:0051169 79 79 2,000 0,05284334 0,14667209 GO:0006913|nucleocytoplasmic transport, ! regulation of cellular component size GO:0032535 35 35 1,000 0,05405765 0,14981692 ! regulation of cell morphogenesis GO:0022604 38 35 1,000 0,05405765 0,14959197 ! regulation of tissue remodeling GO:0034103 35 35 1,000 0,05405765 0,14936769 ! response to steroid hormone stimulus GO:0048545 35 35 1,000 0,05405765 0,14914409 ! tube development GO:0035295 83 81 2,000 0,05616439 0,15472492 ! lymphocyte activation GO:0046649 82 81 2,000 0,05616439 0,15449399 ! embryonic limb morphogenesis GO:0030326 36 36 1,000 0,05684856 0,15614291 GO:0035113|embryonic appendage morphogenesis, ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 1,000 0,05684856 0,15591055 ! positive regulation of organelle organization GO:0010638 36 36 1,000 0,05684856 0,15567889 ! integrin-mediated signaling pathway GO:0007229 36 36 1,000 0,05684856 0,15544791 ! gonad development GO:0008406 36 36 1,000 0,05684856 0,15521761 ! regulation of lipase activity GO:0060191 36 36 1,000 0,05684856 0,154988 ! coagulation GO:0050817 39 36 1,000 0,05684856 0,15475907 GO:0007596|blood coagulation, ! ncRNA processing GO:0034470 83 83 2,000 0,0595832 0,16196435 ! adaptive immune response GO:0002250 37 37 1,000 0,059689 0,16201301 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! regulation of transcription factor activity GO:0051090 38 37 1,000 0,059689 0,16177475 GO:0090046|regulation of transcription regulator activity, ! negative regulation of growth GO:0045926 37 37 1,000 0,059689 0,1615372 ! exocytosis GO:0006887 40 38 1,000 0,06257763 0,16910642 ! RNA elongation GO:0006354 38 38 1,000 0,06257763 0,16885883 ! regulation of homeostatic process GO:0032844 38 38 1,000 0,06257763 0,16861196 ! axon extension GO:0048675 7 6 0,000 0,06284648 0,16908915 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,06284648 0,16884267 ! tRNA modification GO:0006400 6 6 0,000 0,06284648 0,1685969 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,06284648 0,16835185 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,06284648 0,16810751 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,06284648 0,16786387 ! regulation of S phase GO:0033261 6 6 0,000 0,06284648 0,16762094 ! myotube differentiation GO:0014902 6 6 0,000 0,06284648 0,16737872 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,06284648 0,16713719 ! bone remodeling GO:0046849 6 6 0,000 0,06284648 0,16689636 ! N-glycan processing GO:0006491 6 6 0,000 0,06284648 0,16665622 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 0,06284648 0,16641677 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,06284648 0,16617801 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,06284648 0,16593993 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,06284648 0,16570253 ! RNA methylation GO:0001510 6 6 0,000 0,06284648 0,16546582 ! cartilage condensation GO:0001502 7 6 0,000 0,06284648 0,16522977 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,06284648 0,1649944 ! artery development GO:0060840 6 6 0,000 0,06284648 0,1647597 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,06284648 0,16452567 ! bile acid metabolic process GO:0008206 6 6 0,000 0,06284648 0,1642923 ! androgen metabolic process GO:0008209 6 6 0,000 0,06284648 0,16405959 ! estrogen metabolic process GO:0008210 6 6 0,000 0,06284648 0,16382754 ! limbic system development GO:0021761 7 6 0,000 0,06284648 0,16359615 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,06284648 0,1633654 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,06284648 0,16313531 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,06284648 0,16290587 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,06284648 0,16267707 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,06284648 0,16244891 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,06284648 0,16222139 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,06284648 0,16199451 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,06284648 0,16176826 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,06284648 0,16154264 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,06284648 0,16131765 ! arginine metabolic process GO:0006525 6 6 0,000 0,06284648 0,16109328 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,06284648 0,16086954 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,06284648 0,16064642 ! glutamate catabolic process GO:0006538 7 6 0,000 0,06284648 0,16042392 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,06284648 0,16020203 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,06284648 0,15998076 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,06284648 0,1597601 GO:0005978|glycogen biosynthetic process, ! V(D)J recombination GO:0033151 6 6 0,000 0,06284648 0,15954004 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,06284648 0,15932059 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,06284648 0,15910175 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,06284648 0,1588835 ! regulation of heart rate GO:0002027 6 6 0,000 0,06284648 0,15866585 ! lipid digestion GO:0044241 6 6 0,000 0,06284648 0,1584488 ! asymmetric protein localization GO:0008105 6 6 0,000 0,06284648 0,15823234 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,06284648 0,15801647 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,06284648 0,15780119 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,06284648 0,15758649 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,06284648 0,15737238 ! ruffle organization GO:0031529 6 6 0,000 0,06284648 0,15715885 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,06284648 0,1569459 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,06284648 0,15673352 ! neutral amino acid transport GO:0015804 6 6 0,000 0,06284648 0,15652172 ! L-amino acid transport GO:0015807 6 6 0,000 0,06284648 0,15631049 ! bone mineralization GO:0030282 6 6 0,000 0,06284648 0,15609983 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,06284648 0,15588973 ! negative regulation of ossification GO:0030279 6 6 0,000 0,06284648 0,1556802 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,06284648 0,15547124 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,06284648 0,15526283 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,06284648 0,15505498 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,06284648 0,15484769 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,06284648 0,15464095 ! regulation of organ growth GO:0046620 6 6 0,000 0,06284648 0,15443476 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,06284648 0,15422912 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,06284648 0,15402403 ! response to dsRNA GO:0043331 6 6 0,000 0,06284648 0,15381948 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,06284648 0,15361548 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! genitalia development GO:0048806 6 6 0,000 0,06284648 0,15341201 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,06284648 0,15320909 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,06284648 0,1530067 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,06284648 0,15280484 ! multicellular organismal aging GO:0010259 6 6 0,000 0,06284648 0,15260352 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,06284648 0,15240273 ! erythrocyte development GO:0048821 6 6 0,000 0,06284648 0,15220246 ! renal water homeostasis GO:0003091 6 6 0,000 0,06284648 0,15200272 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,06284648 0,1518035 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,06284648 0,15160481 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,06284648 0,15140663 ! ribosome assembly GO:0042255 6 6 0,000 0,06284648 0,15120897 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,06284648 0,15101183 ! diencephalon development GO:0021536 6 6 0,000 0,06284648 0,1508152 ! fucose catabolic process GO:0019317 6 6 0,000 0,06284648 0,15061908 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,06284648 0,15042347 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 0,06284648 0,15022837 ! regulation of lipid transport GO:0032368 6 6 0,000 0,06284648 0,15003377 ! regulation of cell division GO:0051302 6 6 0,000 0,06284648 0,14983968 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,06284648 0,14964609 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,06284648 0,149453 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,06284648 0,1492604 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,06284648 0,1490683 ! neuroblast proliferation GO:0007405 6 6 0,000 0,06284648 0,1488767 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,06284648 0,14868559 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,06284648 0,14849496 ! regulation of glucose transport GO:0010827 6 6 0,000 0,06284648 0,14830483 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,06284648 0,14811518 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,06284648 0,14792602 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,06284648 0,14773734 ! thymus development GO:0048538 6 6 0,000 0,06284648 0,14754914 ! lymph node development GO:0048535 6 6 0,000 0,06284648 0,14736141 ! organic cation transport GO:0015695 6 6 0,000 0,06284648 0,14717417 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,06284648 0,1469874 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,06284648 0,1468011 ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,06284648 0,14661528 ! sperm-egg recognition GO:0035036 7 6 0,000 0,06284648 0,14642993 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,06284648 0,14624504 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,06284648 0,14606062 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,06284648 0,14587666 ! alditol metabolic process GO:0019400 6 6 0,000 0,06284648 0,14569317 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,06284648 0,14551014 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,06284648 0,14532757 ! maternal placenta development GO:0001893 6 6 0,000 0,06284648 0,14514545 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,06284648 0,14496379 ! regulation of cellular localization GO:0060341 86 85 2,000 0,06309832 0,14536275 ! positive regulation of response to stimulus GO:0048584 86 85 2,000 0,06309832 0,14518128 ! hexose metabolic process GO:0019318 87 86 2,000 0,06489153 0,14912106 ! cytokine-mediated signaling pathway GO:0019221 39 39 1,000 0,06551312 0,15036199 ! limb development GO:0060173 39 39 1,000 0,06551312 0,15017497 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! organelle localization GO:0051640 41 40 1,000 0,06849414 0,1568133 ! male gamete generation GO:0048232 90 88 2,000 0,06854829 0,15674255 GO:0007283|spermatogenesis, ! brain development GO:0007420 91 90 2,000 0,07229748 0,16511059 ! respiratory burst GO:0045730 7 7 0,000 0,07293513 0,1663607 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,07293513 0,16615507 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,07293513 0,16594994 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,07293513 0,16574531 ! regulation of chemokine production GO:0032642 7 7 0,000 0,07293513 0,16554119 ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,07293513 0,16533757 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,07293513 0,16513446 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,07293513 0,16493184 ! gene silencing by RNA GO:0031047 7 7 0,000 0,07293513 0,16472972 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,07293513 0,16452809 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,07293513 0,16432695 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,07293513 0,16412631 ! axis specification GO:0009798 7 7 0,000 0,07293513 0,16392616 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,07293513 0,16372649 ! visual behavior GO:0007632 7 7 0,000 0,07293513 0,16352731 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,07293513 0,16332861 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,07293513 0,1631304 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,07293513 0,16293266 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,07293513 0,16273541 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,07293513 0,16253863 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,07293513 0,16234233 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,07293513 0,1621465 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,07293513 0,16195114 ! digestive system development GO:0055123 7 7 0,000 0,07293513 0,16175625 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,07293513 0,16156184 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,07293513 0,16136788 ! protein targeting to ER GO:0045047 8 7 0,000 0,07293513 0,1611744 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,07293513 0,16098137 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,07293513 0,16078881 ! endoderm development GO:0007492 7 7 0,000 0,07293513 0,16059671 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,07293513 0,16040507 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,07293513 0,16021388 GO:0006688|glycosphingolipid biosynthetic process, ! regulation of mRNA processing GO:0050684 7 7 0,000 0,07293513 0,16002315 ! response to hexose stimulus GO:0009746 7 7 0,000 0,07293513 0,15983287 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,07293513 0,15964305 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,07293513 0,15945367 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,07293513 0,15926475 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,07293513 0,15907627 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,07293513 0,15888824 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,07293513 0,15870065 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,07293513 0,1585135 ! UV protection GO:0009650 7 7 0,000 0,07293513 0,15832679 ! DNA integration GO:0015074 7 7 0,000 0,07293513 0,15814053 ! myofibril assembly GO:0030239 7 7 0,000 0,07293513 0,1579547 GO:0055002|striated muscle cell development, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,07293513 0,1577693 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,07293513 0,15758435 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,07293513 0,15739982 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,07293513 0,15721573 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,07293513 0,15703207 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,07293513 0,15684883 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,07293513 0,15666602 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,07293513 0,15648364 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,07293513 0,15630168 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,07293513 0,15612015 ! axon cargo transport GO:0008088 7 7 0,000 0,07293513 0,15593903 ! eating behavior GO:0042755 7 7 0,000 0,07293513 0,15575834 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,07293513 0,15557806 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,07293513 0,15539821 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,07293513 0,15521876 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,07293513 0,15503973 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,07293513 0,15486111 ! cranial nerve development GO:0021545 7 7 0,000 0,07293513 0,15468291 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,07293513 0,15450511 ! induction of an organ GO:0001759 7 7 0,000 0,07293513 0,15432772 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,07293513 0,15415074 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,07293513 0,15397417 ! autonomic nervous system development GO:0048483 7 7 0,000 0,07293513 0,153798 ! intracellular lipid transport GO:0032365 7 7 0,000 0,07293513 0,15362223 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,07293513 0,15344686 ! platelet activation GO:0030168 8 7 0,000 0,07293513 0,15327189 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,07293513 0,15309732 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,07293513 0,15292315 ! natural killer cell activation GO:0030101 7 7 0,000 0,07293513 0,15274937 ! NADP metabolic process GO:0006739 7 7 0,000 0,07293513 0,15257599 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,07293513 0,152403 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,07293513 0,15223041 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,07293513 0,1520582 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,07293513 0,15188638 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,07293513 0,15171495 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,07293513 0,15154391 ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,07293513 0,15137325 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,07293513 0,15120298 ! cell-cell recognition GO:0009988 8 7 0,000 0,07293513 0,15103309 ! hormone catabolic process GO:0042447 7 7 0,000 0,07293513 0,15086358 ! dopamine metabolic process GO:0042417 7 7 0,000 0,07293513 0,15069445 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,07293513 0,1505257 ! oxygen transport GO:0015671 7 7 0,000 0,07293513 0,15035732 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,07293513 0,15018933 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,07293513 0,15002171 ! regulation of axon extension GO:0030516 7 7 0,000 0,07293513 0,14985446 ! cell killing GO:0001906 7 7 0,000 0,07293513 0,14968758 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,07293513 0,14952108 ! adult feeding behavior GO:0008343 7 7 0,000 0,07293513 0,14935494 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,07293513 0,14918918 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,07293513 0,14902378 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,07293513 0,14885875 ! response to cold GO:0009409 7 7 0,000 0,07293513 0,14869408 ! development of primary sexual characteristics GO:0045137 42 42 1,000 0,07458768 0,15189514 ! negative regulation of ligase activity GO:0051352 43 42 1,000 0,07458768 0,15172748 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 1,000 0,07458768 0,1515602 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 2,000 0,07613744 0,15453888 ! mitochondrion organization GO:0007005 44 43 1,000 0,07769769 0,15753227 ! homeostasis of number of cells GO:0048872 44 43 1,000 0,07769769 0,15735916 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 1,000 0,08084821 0,16356009 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,08291662 0,16756068 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,08291662 0,16737715 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,08291662 0,16719403 ! positive regulation of translation GO:0045727 8 8 0,000 0,08291662 0,1670113 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,08291662 0,16682897 ! superoxide anion generation GO:0042554 8 8 0,000 0,08291662 0,16664704 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,08291662 0,16646551 ! cGMP metabolic process GO:0046068 8 8 0,000 0,08291662 0,16628437 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,08291662 0,16610363 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,08291662 0,16592328 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,08291662 0,16574332 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,08291662 0,16556375 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,08291662 0,16538457 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,08291662 0,16520577 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,08291662 0,16502736 ! lipid localization GO:0010876 8 8 0,000 0,08291662 0,16484934 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,08291662 0,1646717 ! response to cAMP GO:0051591 8 8 0,000 0,08291662 0,16449444 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,08291662 0,16431757 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,08291662 0,16414107 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,08291662 0,16396496 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,08291662 0,16378922 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,08291662 0,16361385 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,08291662 0,16343887 ! sensory perception of taste GO:0050909 8 8 0,000 0,08291662 0,16326425 ! organelle fusion GO:0048284 8 8 0,000 0,08291662 0,16309001 ! pancreas development GO:0031016 8 8 0,000 0,08291662 0,16291614 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,08291662 0,16274264 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,08291662 0,16256951 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,08291662 0,16239675 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,08291662 0,16222435 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,08291662 0,16205232 ! sperm motility GO:0030317 8 8 0,000 0,08291662 0,16188066 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,08291662 0,16170935 ! glycine metabolic process GO:0006544 8 8 0,000 0,08291662 0,16153841 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,08291662 0,16136783 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,08291662 0,16119762 GO:0031114|regulation of microtubule depolymerization, ! polyamine metabolic process GO:0006595 8 8 0,000 0,08291662 0,16102775 ! Golgi organization GO:0007030 8 8 0,000 0,08291662 0,16085825 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,08291662 0,16068911 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,08291662 0,16052031 ! mannose metabolic process GO:0006013 9 8 0,000 0,08291662 0,16035188 ! NAD metabolic process GO:0019674 8 8 0,000 0,08291662 0,16018379 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,08291662 0,16001606 ! response to fungus GO:0009620 8 8 0,000 0,08291662 0,15984868 ! stem cell differentiation GO:0048863 8 8 0,000 0,08291662 0,15968165 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,08291662 0,15951497 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,08291662 0,15934863 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,08291662 0,15918264 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,08291662 0,159017 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,08291662 0,1588517 ! regulation of vasodilation GO:0042312 8 8 0,000 0,08291662 0,15868675 ! vasoconstriction GO:0042310 8 8 0,000 0,08291662 0,15852214 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,08291662 0,15835786 ! muscle cell development GO:0055001 8 8 0,000 0,08291662 0,15819393 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,08291662 0,15803034 ! sensory perception of pain GO:0019233 8 8 0,000 0,08291662 0,15786709 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,08291662 0,15770417 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,08291662 0,15754159 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,08291662 0,15737934 ! chromatin silencing GO:0006342 8 8 0,000 0,08291662 0,15721743 ! tissue regeneration GO:0042246 8 8 0,000 0,08291662 0,15705585 ! salivary gland development GO:0007431 8 8 0,000 0,08291662 0,1568946 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,08291662 0,15673368 ! T cell homeostasis GO:0043029 8 8 0,000 0,08291662 0,15657309 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,08291662 0,15641283 ! water homeostasis GO:0030104 8 8 0,000 0,08291662 0,1562529 ! cofactor transport GO:0051181 8 8 0,000 0,08291662 0,1560933 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,08291662 0,15593402 ! acid secretion GO:0046717 8 8 0,000 0,08291662 0,15577507 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,08291662 0,15561643 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,08291662 0,15545813 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,08291662 0,15530014 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,08291662 0,15514248 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,08291662 0,15498513 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,08291662 0,1548281 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,08291662 0,1546714 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,08291662 0,154515 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,08291662 0,15435893 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,08291662 0,15420317 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,08291662 0,15404772 ! developmental induction GO:0031128 8 8 0,000 0,08291662 0,15389259 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,08291662 0,15373777 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,08291662 0,15358326 ! actin filament polymerization GO:0030041 9 8 0,000 0,08291662 0,15342906 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 0,08291662 0,15327516 ! peptide hormone processing GO:0016486 8 8 0,000 0,08291662 0,15312158 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,08291662 0,15296831 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,08291662 0,15281534 ! amine biosynthetic process GO:0009309 46 45 1,000 0,08403804 0,15472738 ! homophilic cell adhesion GO:0007156 45 45 1,000 0,08403804 0,15457296 ! regulation of actin cytoskeleton organization GO:0032956 46 45 1,000 0,08403804 0,15441885 ! regulation of DNA binding GO:0051101 47 45 1,000 0,08403804 0,15426505 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 1,000 0,08403804 0,15411155 ! steroid biosynthetic process GO:0006694 46 45 1,000 0,08403804 0,15395836 ! regulation of cell growth GO:0001558 97 96 2,000 0,08408281 0,15388741 ! regulation of actin filament-based process GO:0032970 47 46 1,000 0,087266 0,15955481 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 1,000 0,087266 0,15939668 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 1,000 0,087266 0,15923886 ! positive regulation of ligase activity GO:0051351 47 46 1,000 0,087266 0,15908135 ! regulation of membrane potential GO:0042391 46 46 1,000 0,087266 0,15892416 ! blood circulation GO:0008015 99 98 2,000 0,08818466 0,16043862 GO:0003013|circulatory system process, ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 1,000 0,09053094 0,16454489 ! amine transport GO:0015837 47 47 1,000 0,09053094 0,16438278 ! lactation GO:0007595 10 9 0,000 0,09279209 0,16832265 ! embryonic pattern specification GO:0009880 10 9 0,000 0,09279209 0,16815714 ! positive regulation of cell size GO:0045793 9 9 0,000 0,09279209 0,16799196 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,09279209 0,1678271 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,09279209 0,16766256 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,09279209 0,16749835 ! viral genome replication GO:0019079 9 9 0,000 0,09279209 0,16733446 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,09279209 0,16717088 ! copper ion transport GO:0006825 9 9 0,000 0,09279209 0,16700763 ! lipid phosphorylation GO:0046834 9 9 0,000 0,09279209 0,1668447 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,09279209 0,16668208 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,09279209 0,16651978 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,09279209 0,1663578 ! RNA polyadenylation GO:0043631 9 9 0,000 0,09279209 0,16619613 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,09279209 0,16603477 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,09279209 0,16587373 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,09279209 0,165713 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,09279209 0,16555258 ! phospholipid efflux GO:0033700 9 9 0,000 0,09279209 0,16539247 ! response to alkaloid GO:0043279 10 9 0,000 0,09279209 0,16523267 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,09279209 0,16507318 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,09279209 0,164914 GO:0042107|cytokine metabolic process, ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,09279209 0,16475512 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,09279209 0,16459655 ! response to ethanol GO:0045471 9 9 0,000 0,09279209 0,16443828 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,09279209 0,16428032 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,09279209 0,16412266 ! methionine metabolic process GO:0006555 9 9 0,000 0,09279209 0,16396531 ! glutamine metabolic process GO:0006541 9 9 0,000 0,09279209 0,16380825 ! cerebral cortex development GO:0021987 9 9 0,000 0,09279209 0,1636515 ! response to osmotic stress GO:0006970 9 9 0,000 0,09279209 0,16349504 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,09279209 0,16333889 ! central nervous system neuron development GO:0021954 10 9 0,000 0,09279209 0,16318303 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,09279209 0,16302747 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,09279209 0,1628722 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,09279209 0,16271724 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,09279209 0,16256256 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,09279209 0,16240818 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,09279209 0,16225409 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,09279209 0,1621003 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,09279209 0,16194679 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,09279209 0,16179358 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,09279209 0,16164066 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,09279209 0,16148802 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,09279209 0,16133567 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,09279209 0,16118361 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,09279209 0,16103184 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,09279209 0,16088035 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,09279209 0,16072915 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,09279209 0,16057823 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,09279209 0,16042759 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,09279209 0,16027724 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,09279209 0,16012717 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,09279209 0,15997738 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,09279209 0,15982786 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,09279209 0,15967863 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,09279209 0,15952968 ! collagen catabolic process GO:0030574 9 9 0,000 0,09279209 0,159381 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,09279209 0,1592326 ! purine base metabolic process GO:0006144 9 9 0,000 0,09279209 0,15908448 ! gas transport GO:0015669 9 9 0,000 0,09279209 0,15893663 ! cholesterol efflux GO:0033344 9 9 0,000 0,09279209 0,15878906 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,09279209 0,15864176 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,09279209 0,15849473 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,09279209 0,15834798 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,09279209 0,15820149 ! defense response to virus GO:0051607 9 9 0,000 0,09279209 0,15805528 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,09279209 0,15790934 ! actin filament-based movement GO:0030048 9 9 0,000 0,09279209 0,15776367 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,09279209 0,15761826 ! actin filament organization GO:0007015 50 48 1,000 0,0938317 0,1592374 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 1,000 0,0938317 0,15909091 ! glycerophospholipid metabolic process GO:0006650 49 48 1,000 0,0938317 0,15894468 ! DNA recombination GO:0006310 48 48 1,000 0,0938317 0,15879873 ! ossification GO:0001503 50 49 1,000 0,09716716 0,16429273 GO:0060348|bone development, ! cell cycle arrest GO:0007050 49 49 1,000 0,09716716 0,16414214 ! response to bacterium GO:0009617 50 49 1,000 0,09716716 0,16399183 ! regulation of ligase activity GO:0051340 50 49 1,000 0,09716716 0,16384179 ! negative regulation of transport GO:0051051 51 50 1,000 0,10053622 0,16936769 ! regulation of neurogenesis GO:0050767 51 50 1,000 0,10053622 0,16921302 ! transcription initiation GO:0006352 50 50 1,000 0,10053622 0,16905863 ! anatomical structure homeostasis GO:0060249 51 50 1,000 0,10053622 0,16890452 ! anterior/posterior pattern formation GO:0009952 51 50 1,000 0,10053622 0,16875069 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,10256263 0,17199538 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,10256263 0,17183902 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,10256263 0,17168294 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,10256263 0,17152715 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,10256263 0,17137164 ! neuron maturation GO:0042551 10 10 0,000 0,10256263 0,17121641 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,10256263 0,17106147 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,10256263 0,1709068 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,10256263 0,17075241 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,10256263 0,1705983 ! hormone secretion GO:0046879 10 10 0,000 0,10256263 0,17044447 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,10256263 0,17029092 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,10256263 0,17013764 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 0,000 0,10256263 0,16998464 ! cAMP metabolic process GO:0046058 10 10 0,000 0,10256263 0,16983191 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,10256263 0,16967946 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,10256263 0,16952728 ! glial cell development GO:0021782 10 10 0,000 0,10256263 0,16937538 ! phototransduction GO:0007602 11 10 0,000 0,10256263 0,16922374 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,10256263 0,16907238 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,10256263 0,16892129 ! fat cell differentiation GO:0045444 10 10 0,000 0,10256263 0,16877047 ! myoblast differentiation GO:0045445 10 10 0,000 0,10256263 0,16861991 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,10256263 0,16846963 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,10256263 0,16831961 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,10256263 0,16816986 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,10256263 0,16802037 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,10256263 0,16787116 ! protein polyubiquitination GO:0000209 10 10 0,000 0,10256263 0,1677222 ! glutamate metabolic process GO:0006536 11 10 0,000 0,10256263 0,16757351 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,10256263 0,16742508 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! lysosomal transport GO:0007041 10 10 0,000 0,10256263 0,16727692 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,10256263 0,16712902 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,10256263 0,16698138 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,10256263 0,166834 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,10256263 0,16668688 ! exocrine system development GO:0035272 10 10 0,000 0,10256263 0,16654002 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,10256263 0,16639342 ! embryo implantation GO:0007566 11 10 0,000 0,10256263 0,16624707 ! regulation of protein binding GO:0043393 11 10 0,000 0,10256263 0,16610098 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,10256263 0,16595515 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,10256263 0,16580958 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,10256263 0,16566426 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,10256263 0,1655192 ! protein export from nucleus GO:0006611 10 10 0,000 0,10256263 0,16537438 ! negative regulation of immune response GO:0050777 10 10 0,000 0,10256263 0,16522983 ! cytolysis GO:0019835 10 10 0,000 0,10256263 0,16508552 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,10256263 0,16494147 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,10256263 0,16479766 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,10256263 0,16465411 ! histone deacetylation GO:0016575 10 10 0,000 0,10256263 0,16451081 ! mRNA splice site selection GO:0006376 11 10 0,000 0,10256263 0,16436776 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,10256263 0,16422495 ! gland morphogenesis GO:0022612 10 10 0,000 0,10256263 0,1640824 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,10256263 0,16394009 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,10256263 0,16379802 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,10256263 0,16365621 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,10256263 0,16351464 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,10256263 0,16337331 ! regulation of epidermis development GO:0045682 10 10 0,000 0,10256263 0,16323223 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,10256263 0,16309139 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,10256263 0,16295079 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,10256263 0,16281044 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,10256263 0,16267033 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,10256263 0,16253046 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,10256263 0,16239083 ! nerve development GO:0021675 10 10 0,000 0,10256263 0,16225143 ! gut development GO:0048565 10 10 0,000 0,10256263 0,16211228 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,10256263 0,16197337 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,10256263 0,16183469 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,10256263 0,16169625 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,10256263 0,16155805 ! protein stabilization GO:0050821 10 10 0,000 0,10256263 0,16142009 ! cell fate commitment GO:0045165 52 52 1,000 0,10737083 0,16884338 ! regulation of T cell activation GO:0050863 53 53 1,000 0,11083426 0,17414113 ! protein secretion GO:0009306 11 11 0,000 0,11222935 0,17618287 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,11222935 0,17603292 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,11222935 0,17588324 ! negative regulation of defense response GO:0031348 11 11 0,000 0,11222935 0,1757338 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,11222935 0,17558462 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,11222935 0,1754357 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,11222935 0,17528702 ! skin development GO:0043588 11 11 0,000 0,11222935 0,1751386 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,11222935 0,17499043 ! signal complex assembly GO:0007172 11 11 0,000 0,11222935 0,17484251 ! microtubule-based transport GO:0010970 11 11 0,000 0,11222935 0,17469484 ! peroxisomal transport GO:0043574 11 11 0,000 0,11222935 0,17454741 ! protein amino acid methylation GO:0006479 11 11 0,000 0,11222935 0,17440024 GO:0008213|protein amino acid alkylation, ! heart contraction GO:0060047 11 11 0,000 0,11222935 0,17425332 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,11222935 0,17410664 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,11222935 0,17396021 ! T cell proliferation GO:0042098 11 11 0,000 0,11222935 0,17381402 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,11222935 0,17366808 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,11222935 0,17352239 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,11222935 0,17337694 ! spinal cord development GO:0021510 11 11 0,000 0,11222935 0,17323173 ! smooth muscle contraction GO:0006939 11 11 0,000 0,11222935 0,17308677 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,11222935 0,17294204 ! digestive system process GO:0022600 11 11 0,000 0,11222935 0,17279757 ! mitotic spindle organization GO:0007052 11 11 0,000 0,11222935 0,17265333 ! fucose metabolic process GO:0006004 11 11 0,000 0,11222935 0,17250933 ! membrane budding GO:0006900 11 11 0,000 0,11222935 0,17236557 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,11222935 0,17222205 ! monoamine transport GO:0015844 11 11 0,000 0,11222935 0,17207877 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,11222935 0,17193573 ! body fluid secretion GO:0007589 11 11 0,000 0,11222935 0,17179293 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,11222935 0,17165036 ! intermediate filament-based process GO:0045103 11 11 0,000 0,11222935 0,17150803 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,11222935 0,17136594 GO:0060415|muscle tissue morphogenesis, ! membrane depolarization GO:0051899 11 11 0,000 0,11222935 0,17122408 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,11222935 0,17108245 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,11222935 0,17094106 ! oogenesis GO:0048477 11 11 0,000 0,11222935 0,17079991 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,11222935 0,17065898 ! vitamin transport GO:0051180 11 11 0,000 0,11222935 0,17051829 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,11222935 0,17037783 ! hindbrain development GO:0030902 11 11 0,000 0,11222935 0,1702376 ! steroid catabolic process GO:0006706 11 11 0,000 0,11222935 0,1700976 ! endocrine process GO:0050886 11 11 0,000 0,11222935 0,16995784 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,11222935 0,1698183 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,11222935 0,16967899 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,11222935 0,16953991 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,11222935 0,16940105 ! sulfur metabolic process GO:0006790 55 54 1,000 0,11432707 0,17242618 ! negative regulation of multicellular organismal process GO:0051241 55 54 1,000 0,11432707 0,17228519 ! extracellular structure organization GO:0043062 56 56 1,000 0,12139679 0,18278944 ! regulation of nervous system development GO:0051960 57 56 1,000 0,12139679 0,18264023 ! translational initiation GO:0006413 12 12 0,000 0,12179333 0,18308737 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,12179333 0,18293815 ! initiation of viral infection GO:0019059 12 12 0,000 0,12179333 0,18278918 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,12179333 0,18264045 ! iron ion transport GO:0006826 13 12 0,000 0,12179333 0,18249196 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,12179333 0,18234372 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,12179333 0,18219571 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,12179333 0,18204794 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,12179333 0,18190042 ! collagen metabolic process GO:0032963 12 12 0,000 0,12179333 0,18175313 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,12179333 0,18160608 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,12179333 0,18145927 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,12179333 0,18131269 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,12179333 0,18116636 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,12179333 0,18102025 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,12179333 0,18087439 ! actomyosin structure organization GO:0031032 12 12 0,000 0,12179333 0,18072876 ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,12179333 0,18058336 ! retinoid metabolic process GO:0001523 12 12 0,000 0,12179333 0,18043819 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,12179333 0,18029326 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,12179333 0,18014857 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,12179333 0,1800041 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,12179333 0,17985987 ! acute-phase response GO:0006953 12 12 0,000 0,12179333 0,17971586 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,12179333 0,17957209 ! vacuolar transport GO:0007034 12 12 0,000 0,12179333 0,17942855 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,12179333 0,17928523 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,12179333 0,17914215 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,12179333 0,17899929 ! osteoblast differentiation GO:0001649 12 12 0,000 0,12179333 0,17885666 ! male gonad development GO:0008584 12 12 0,000 0,12179333 0,17871426 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,12179333 0,17857209 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,12179333 0,17843014 ! renal system process GO:0003014 12 12 0,000 0,12179333 0,17828841 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,12179333 0,17814692 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,12179333 0,17800564 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,12179333 0,17786459 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,12179333 0,17772376 ! pallium development GO:0021543 13 12 0,000 0,12179333 0,17758316 ! cell fate determination GO:0001709 12 12 0,000 0,12179333 0,17744278 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,12179333 0,17730262 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,12179333 0,17716268 ! detection of light stimulus GO:0009583 13 12 0,000 0,12179333 0,17702296 ! synaptogenesis GO:0007416 12 12 0,000 0,12179333 0,17688346 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,12179333 0,17674418 ! hormone transport GO:0009914 12 12 0,000 0,12179333 0,17660513 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,12179333 0,17646628 ! heme biosynthetic process GO:0006783 12 12 0,000 0,12179333 0,17632766 ! spermatid differentiation GO:0048515 13 12 0,000 0,12179333 0,17618926 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,12179333 0,17605107 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,12179333 0,1759131 ! neural tube closure GO:0001843 13 12 0,000 0,12179333 0,17577534 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,12179333 0,1756378 ! regulation of binding GO:0051098 60 57 1,000 0,12497173 0,18008045 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,13125567 0,18898765 GO:0016444|somatic cell DNA recombination, ! phenol metabolic process GO:0018958 13 13 0,000 0,13125567 0,18884012 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! gluconeogenesis GO:0006094 13 13 0,000 0,13125567 0,18869282 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,13125567 0,18854575 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,13125567 0,1883989 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,13125567 0,18825229 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,13125567 0,1881059 ! regeneration GO:0031099 13 13 0,000 0,13125567 0,18795974 ! keratinization GO:0031424 13 13 0,000 0,13125567 0,18781381 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,13125567 0,18766811 ! patterning of blood vessels GO:0001569 13 13 0,000 0,13125567 0,18752263 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,13125567 0,18737738 ! regulation of innate immune response GO:0045088 13 13 0,000 0,13125567 0,18723235 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,13125567 0,18708754 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,13125567 0,18694296 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,13125567 0,1867986 ! autophagy GO:0006914 13 13 0,000 0,13125567 0,18665447 ! receptor metabolic process GO:0043112 14 13 0,000 0,13125567 0,18651056 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,13125567 0,18636687 ! ureteric bud development GO:0001657 13 13 0,000 0,13125567 0,1862234 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,13125567 0,18608015 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,13125567 0,18593712 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,13125567 0,18579431 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,13125567 0,18565172 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,13125567 0,18550935 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,13125567 0,1853672 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,13125567 0,18522526 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,13125567 0,18508354 ! vasodilation GO:0042311 14 13 0,000 0,13125567 0,18494204 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,13125567 0,18480076 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,13125567 0,18465969 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,13125567 0,18451883 GO:0006664|glycolipid metabolic process, ! neural crest cell migration GO:0001755 14 13 0,000 0,13125567 0,18437819 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,13125567 0,18423777 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,13125567 0,18409756 ! immunoglobulin production GO:0002377 13 13 0,000 0,13125567 0,18395756 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,13125567 0,18381777 ! negative regulation of intracellular transport GO:0032387 13 13 0,000 0,13125567 0,1836782 ! cell-cell junction organization GO:0045216 13 13 0,000 0,13125567 0,18353884 ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,13125567 0,18339969 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,13125567 0,18326075 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,13125567 0,18312202 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,13125567 0,1829835 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,13125567 0,18284519 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,13125567 0,18270709 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,13125567 0,1825692 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,13125567 0,18243152 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,13125567 0,18229404 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,13125567 0,18215677 ! blastocyst development GO:0001824 13 13 0,000 0,13125567 0,18201971 ! telomere organization GO:0032200 13 13 0,000 0,13125567 0,18188285 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,13125567 0,1817462 ! regulation of amine transport GO:0051952 13 13 0,000 0,13125567 0,18160975 ! tissue homeostasis GO:0001894 13 13 0,000 0,13125567 0,18147351 GO:0048871|multicellular organismal homeostasis, ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,13125567 0,18133747 ! carboxylic acid transport GO:0046942 59 59 1,000 0,132197 0,18250117 GO:0015849|organic acid transport, ! regulation of cell development GO:0060284 60 59 1,000 0,132197 0,18236457 ! proteasomal protein catabolic process GO:0010498 62 61 1,000 0,13951658 0,19231792 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! neuron fate commitment GO:0048663 14 14 0,000 0,14061741 0,19369049 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,14061741 0,19354584 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,14061741 0,1934014 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,14061741 0,19325718 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,14061741 0,19311318 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,14061741 0,19296938 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,14061741 0,1928258 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,14061741 0,19268244 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,14061741 0,19253929 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,14061741 0,19239635 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,14061741 0,19225362 ! vesicle docking GO:0048278 14 14 0,000 0,14061741 0,19211111 ! superoxide metabolic process GO:0006801 15 14 0,000 0,14061741 0,1919688 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,14061741 0,19182671 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,14061741 0,19168482 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,14061741 0,19154315 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,14061741 0,19140168 ! hair cycle GO:0042633 14 14 0,000 0,14061741 0,19126043 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,14061741 0,19111938 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,14061741 0,19097854 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,14061741 0,19083791 ! lysosome organization GO:0007040 14 14 0,000 0,14061741 0,19069748 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,14061741 0,19055727 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,14061741 0,19041725 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,14061741 0,19027745 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,14061741 0,19013784 ! primary neural tube formation GO:0014020 15 14 0,000 0,14061741 0,18999845 ! peptide cross-linking GO:0018149 14 14 0,000 0,14061741 0,18985925 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,14061741 0,18972026 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,14061741 0,18958148 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,14061741 0,1894429 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,14061741 0,18930452 ! formation of primary germ layer GO:0001704 14 14 0,000 0,14061741 0,18916634 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,14061741 0,18902836 ! collagen fibril organization GO:0030199 14 14 0,000 0,14061741 0,18889058 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,14061741 0,18875301 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,14061741 0,18861563 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,14061741 0,18847846 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,14061741 0,18834148 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,14061741 0,18820471 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,14061741 0,18806813 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,14061741 0,18793175 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,14061741 0,18779557 ! regulation of lymphocyte activation GO:0051249 62 62 1,000 0,14320948 0,19111881 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,14987961 0,19987564 ! positive regulation of ossification GO:0045778 15 15 0,000 0,14987961 0,19973111 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,14987961 0,1995868 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,14987961 0,19944269 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,14987961 0,19929879 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,14987961 0,1991551 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,14987961 0,19901162 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,14987961 0,19886834 ! ovarian follicle development GO:0001541 15 15 0,000 0,14987961 0,19872527 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,14987961 0,19858241 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,14987961 0,19843975 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,14987961 0,19829729 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,14987961 0,19815504 ! heme metabolic process GO:0042168 15 15 0,000 0,14987961 0,198013 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,14987961 0,19787115 ! chromosome condensation GO:0030261 15 15 0,000 0,14987961 0,19772951 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,14987961 0,19758807 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,14987961 0,19744684 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,14987961 0,19730581 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,14987961 0,19716497 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,14987961 0,19702434 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,14987961 0,19688391 ! phospholipid transport GO:0015914 15 15 0,000 0,14987961 0,19674368 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,14987961 0,19660365 ! glutathione metabolic process GO:0006749 16 15 0,000 0,14987961 0,19646382 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,14987961 0,19632419 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,14987961 0,19618475 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,14987961 0,19604551 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,14987961 0,19590647 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,14987961 0,19576763 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,14987961 0,19562899 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,14987961 0,19549054 ! glycerolipid metabolic process GO:0046486 65 64 1,000 0,15065713 0,1963657 ! regulation of response to external stimulus GO:0032101 65 64 1,000 0,15065713 0,19622692 ! positive regulation of cellular component organization GO:0051130 65 65 1,000 0,15441018 0,20097314 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,15904333 0,20685734 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,15904333 0,20671146 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,15904333 0,20656579 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,15904333 0,20642032 ! learning GO:0007612 16 16 0,000 0,15904333 0,20627506 ! circadian rhythm GO:0007623 16 16 0,000 0,15904333 0,20613 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,15904333 0,20598514 ! vacuole organization GO:0007033 16 16 0,000 0,15904333 0,20584049 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,15904333 0,20569604 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,15904333 0,20555179 ! vesicle targeting GO:0006903 17 16 0,000 0,15904333 0,20540775 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,15904333 0,20526391 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,15904333 0,20512026 ! iron ion homeostasis GO:0055072 16 16 0,000 0,15904333 0,20497682 ! positive regulation of cell development GO:0010720 16 16 0,000 0,15904333 0,20483358 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,15904333 0,20469054 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,15904333 0,2045477 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,15904333 0,20440506 ! cell fate specification GO:0001708 16 16 0,000 0,15904333 0,20426262 ! pentose metabolic process GO:0019321 16 16 0,000 0,15904333 0,20412037 ! fatty acid transport GO:0015908 16 16 0,000 0,15904333 0,20397833 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,15904333 0,20383648 ! cofactor catabolic process GO:0051187 16 16 0,000 0,15904333 0,20369483 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,15904333 0,20355337 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,15904333 0,20341211 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,15904333 0,20327105 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,15904333 0,20313018 GO:0001841|neural tube formation, ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,15904333 0,20298951 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,15904333 0,20284904 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,15904333 0,20270875 ! regulation of coagulation GO:0050818 17 16 0,000 0,15904333 0,20256866 ! negative regulation of cell differentiation GO:0045596 68 67 1,000 0,16197057 0,20615453 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,16810959 0,21382054 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,16810959 0,21367308 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,16810959 0,21352582 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,16810959 0,21337877 ! sensory perception of smell GO:0007608 17 17 0,000 0,16810959 0,21323191 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,16810959 0,21308526 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,16810959 0,21293881 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,16810959 0,21279256 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,16810959 0,21264651 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,16810959 0,21250067 ! neural crest cell development GO:0014032 19 17 0,000 0,16810959 0,21235502 GO:0014033|neural crest cell differentiation, ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,16810959 0,21220957 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,16810959 0,21206432 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,16810959 0,21191927 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,16810959 0,21177442 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,16810959 0,21162976 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,16810959 0,2114853 ! adult locomotory behavior GO:0008344 17 17 0,000 0,16810959 0,21134104 ! embryonic organ development GO:0048568 17 17 0,000 0,16810959 0,21119698 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,16810959 0,21105311 ! liver development GO:0001889 17 17 0,000 0,16810959 0,21090944 ! gene silencing GO:0016458 17 17 0,000 0,16810959 0,21076597 ! regionalization GO:0003002 70 69 1,000 0,16959802 0,21248753 ! regulation of leukocyte activation GO:0002694 69 69 1,000 0,16959802 0,21234317 ! growth GO:0040007 70 70 1,000 0,17343494 0,21699973 ! carboxylic acid biosynthetic process GO:0046394 70 70 1,000 0,17343494 0,21685251 GO:0016053|organic acid biosynthetic process, ! mRNA export from nucleus GO:0006406 18 18 0,000 0,17707941 0,22125922 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,17707941 0,22110932 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,17707941 0,22095962 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,17707941 0,22081012 ! membrane docking GO:0022406 18 18 0,000 0,17707941 0,22066082 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,17707941 0,22051172 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,17707941 0,22036283 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,17707941 0,22021414 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,17707941 0,22006565 ! cholesterol homeostasis GO:0042632 18 18 0,000 0,17707941 0,21991735 GO:0055092|sterol homeostasis, ! striated muscle contraction GO:0006941 18 18 0,000 0,17707941 0,21976926 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,17707941 0,21962137 GO:0006639|acylglycerol metabolic process, ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,17707941 0,21947367 ! ceramide metabolic process GO:0006672 18 18 0,000 0,17707941 0,21932618 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,17707941 0,21917888 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,17707941 0,21903178 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,17707941 0,21888488 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,17707941 0,21873817 ! BMP signaling pathway GO:0030509 18 18 0,000 0,17707941 0,21859166 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,17707941 0,21844535 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,17707941 0,21829923 ! regulation of cell activation GO:0050865 71 71 1,000 0,17728631 0,21840821 ! secretion by cell GO:0032940 75 72 1,000 0,1811514 0,22302073 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,18595381 0,22878029 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,18595381 0,22862766 GO:0006956|complement activation, ! glial cell differentiation GO:0010001 19 19 0,000 0,18595381 0,22847525 ! feeding behavior GO:0007631 19 19 0,000 0,18595381 0,22832303 ! peroxisome organization GO:0007031 19 19 0,000 0,18595381 0,22817102 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,18595381 0,22801921 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,18595381 0,2278676 ! metanephros development GO:0001656 19 19 0,000 0,18595381 0,22771619 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,18595381 0,22756499 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,18595381 0,22741398 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,18595381 0,22726318 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,18595381 0,22711257 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,18595381 0,22696216 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,18595381 0,22681196 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,18595381 0,22666195 ! dorsal/ventral pattern formation GO:0009953 19 19 0,000 0,18595381 0,22651214 ! eye morphogenesis GO:0048592 19 19 0,000 0,18595381 0,22636253 ! placenta development GO:0001890 19 19 0,000 0,18595381 0,22621311 ! response to heat GO:0009408 19 19 0,000 0,18595381 0,2260639 ! vesicle localization GO:0051648 20 19 0,000 0,18595381 0,22591488 ! regulation of muscle development GO:0048634 21 20 0,000 0,19473378 0,2364258 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,19473378 0,23627015 ! negative regulation of binding GO:0051100 21 20 0,000 0,19473378 0,23611471 ! organic ether metabolic process GO:0018904 20 20 0,000 0,19473378 0,23595948 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,19473378 0,23580445 ! neural tube development GO:0021915 21 20 0,000 0,19473378 0,23564962 ! nucleus organization GO:0006997 20 20 0,000 0,19473378 0,23549499 ! phagocytosis GO:0006909 21 20 0,000 0,19473378 0,23534057 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,19473378 0,23518635 ! protein targeting to membrane GO:0006612 22 20 0,000 0,19473378 0,23503233 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,19473378 0,23487851 ! chromatin remodeling GO:0006338 20 20 0,000 0,19473378 0,2347249 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,19473378 0,23457148 ! lipid oxidation GO:0034440 20 20 0,000 0,19473378 0,23441827 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,19473378 0,23426525 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,19473378 0,23411244 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,19473378 0,23395982 ! RNA modification GO:0009451 20 20 0,000 0,19473378 0,2338074 ! single fertilization GO:0007338 21 20 0,000 0,19473378 0,23365519 ! regulation of B cell activation GO:0050864 20 20 0,000 0,19473378 0,23350317 ! positive regulation of multicellular organismal process GO:0051240 76 76 1,000 0,19673454 0,23574886 ! mRNA catabolic process GO:0006402 21 21 0,000 0,20342033 0,24360212 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,20342033 0,24344394 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! protein amino acid lipidation GO:0006497 21 21 0,000 0,20342033 0,24328596 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,20342033 0,24312819 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,20342033 0,24297062 ! ear morphogenesis GO:0042471 21 21 0,000 0,20342033 0,24281326 ! organic anion transport GO:0015711 21 21 0,000 0,20342033 0,2426561 ! cholesterol transport GO:0030301 21 21 0,000 0,20342033 0,24249914 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,20342033 0,24234238 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,20342033 0,24218583 GO:0032313|regulation of Rab GTPase activity, ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,20342033 0,24202948 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,20342033 0,24187333 ! negative regulation of protein transport GO:0051224 21 21 0,000 0,20342033 0,24171739 ! positive regulation of protein kinase cascade GO:0010740 79 78 1,000 0,20459012 0,24295077 ! RNA export from nucleus GO:0006405 22 22 0,000 0,21201442 0,25160501 ! regulation of ion transport GO:0043269 22 22 0,000 0,21201442 0,2514431 ! odontogenesis GO:0042476 22 22 0,000 0,21201442 0,2512814 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,21201442 0,25111991 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,21201442 0,25095863 ! embryonic skeletal system development GO:0048706 22 22 0,000 0,21201442 0,25079755 ! maintenance of protein location in cell GO:0032507 23 22 0,000 0,21201442 0,25063668 ! ovulation cycle process GO:0022602 22 22 0,000 0,21201442 0,25047602 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,21201442 0,25031556 ! cell chemotaxis GO:0060326 23 22 0,000 0,21201442 0,2501553 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,21201442 0,24999526 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,21201442 0,24983541 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,21201442 0,24967577 ! biopolymer methylation GO:0043414 22 22 0,000 0,21201442 0,24951634 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,21201442 0,24935711 ! detection of external stimulus GO:0009581 23 22 0,000 0,21201442 0,24919808 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,21201442 0,24903925 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,21201442 0,24888063 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,21201442 0,24872221 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,21201442 0,24856399 ! aerobic respiration GO:0009060 22 22 0,000 0,21201442 0,24840597 ! cytokine production GO:0001816 22 22 0,000 0,21201442 0,24824815 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,21201442 0,24809053 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,22051704 0,25787621 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,22051704 0,25771268 ! viral infectious cycle GO:0019058 23 23 0,000 0,22051704 0,25754937 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,22051704 0,25738626 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,22051704 0,25722336 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,22051704 0,25706066 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,22051704 0,25689817 ! endocrine system development GO:0035270 23 23 0,000 0,22051704 0,25673588 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,22051704 0,2565738 ! female gonad development GO:0008585 23 23 0,000 0,22051704 0,25641193 ! lipid homeostasis GO:0055088 23 23 0,000 0,22051704 0,25625025 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,22051704 0,25608879 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,22051704 0,25592752 ! cellular amino acid derivative metabolic process GO:0006575 87 84 1,000 0,22835074 0,26485237 ! gliogenesis GO:0042063 24 24 0,000 0,22892914 0,26535622 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,22892914 0,26518944 ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,22892914 0,26502286 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,22892914 0,26485649 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,22892914 0,26469034 ! ovulation cycle GO:0042698 24 24 0,000 0,22892914 0,26452439 ! fertilization GO:0009566 25 24 0,000 0,22892914 0,26435864 ! maintenance of protein location GO:0045185 25 24 0,000 0,22892914 0,26419311 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,22892914 0,26402778 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,22892914 0,26386266 ! nitrogen compound biosynthetic process GO:0044271 86 85 1,000 0,23233272 0,26761826 ! organophosphate metabolic process GO:0019637 87 86 1,000 0,23631942 0,27204041 GO:0006644|phospholipid metabolic process, ! negative regulation of secretion GO:0051048 26 25 0,000 0,23725166 0,27294308 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,23725166 0,27277281 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,23725166 0,27260275 ! cellular component disassembly GO:0022411 26 25 0,000 0,23725166 0,27243291 ! endosome transport GO:0016197 25 25 0,000 0,23725166 0,27226327 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,23725166 0,27209385 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,23725166 0,27192463 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,23725166 0,27175563 ! excretion GO:0007588 25 25 0,000 0,23725166 0,27158684 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,23725166 0,27141826 ! gastrulation GO:0007369 25 25 0,000 0,23725166 0,27124988 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,23725166 0,27108172 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,23725166 0,27091376 ! positive regulation of defense response GO:0031349 26 26 0,000 0,24548556 0,28014235 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,24548556 0,27996899 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,24548556 0,27979585 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,24548556 0,27962292 ! cellular defense response GO:0006968 26 26 0,000 0,24548556 0,27945021 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,24548556 0,27927771 ! regulation of protein secretion GO:0050708 26 26 0,000 0,24548556 0,27910542 ! germ cell development GO:0007281 27 26 0,000 0,24548556 0,27893335 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,24548556 0,27876148 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,24548556 0,27858983 ! maintenance of location in cell GO:0051651 27 26 0,000 0,24548556 0,27841839 ! chloride transport GO:0006821 27 27 0,000 0,25363176 0,28748053 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,25363176 0,28730383 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,25363176 0,28712736 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,25363176 0,2869511 ! peptide metabolic process GO:0006518 29 27 0,000 0,25363176 0,28677505 ! inner ear development GO:0048839 27 27 0,000 0,25363176 0,28659923 ! defense response to bacterium GO:0042742 27 27 0,000 0,25363176 0,28642361 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,25363176 0,28624822 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,25363176 0,28607303 ! fatty acid metabolic process GO:0006631 93 92 1,000 0,26030827 0,29342394 ! positive regulation of immune system process GO:0002684 92 92 1,000 0,26030827 0,29324458 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,26169119 0,2946224 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! neuromuscular process GO:0050905 28 28 0,000 0,26169119 0,29444253 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,26169119 0,29426288 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,26169119 0,29408345 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,26169119 0,29390424 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,26169119 0,29372525 ! developmental growth GO:0048589 28 28 0,000 0,26169119 0,29354648 ! cartilage development GO:0051216 29 28 0,000 0,26169119 0,29336792 ! regulation of response to stress GO:0080134 97 94 1,000 0,2683184 0,30061448 ! pattern specification process GO:0007389 96 94 1,000 0,2683184 0,30043184 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,26966475 0,301756 ! leukocyte migration GO:0050900 30 29 0,000 0,26966475 0,3015729 ! branching morphogenesis of a tube GO:0048754 29 29 0,000 0,26966475 0,30139002 ! antigen processing and presentation GO:0019882 29 29 0,000 0,26966475 0,30120736 ! tRNA processing GO:0008033 29 29 0,000 0,26966475 0,30102492 ! adult behavior GO:0030534 30 29 0,000 0,26966475 0,3008427 ! RNA catabolic process GO:0006401 30 30 0,000 0,27755335 0,30945604 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,27755335 0,30926894 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,27755335 0,30908207 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,27755335 0,30889543 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,27755335 0,30870901 ! skeletal system morphogenesis GO:0048705 31 30 0,000 0,27755335 0,30852282 ! response to temperature stimulus GO:0009266 30 30 0,000 0,27755335 0,30833685 ! regulation of ossification GO:0030278 30 30 0,000 0,27755335 0,3081511 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,27755335 0,30796558 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,27755335 0,30778028 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,27755335 0,30759521 ! vesicle organization GO:0016050 30 30 0,000 0,27755335 0,30741035 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,27755335 0,30722572 ! endocytosis GO:0006897 99 98 1,000 0,28433644 0,31454505 GO:0010324|membrane invagination, ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,28535789 0,31548565 ! ion transmembrane transport GO:0034220 31 31 0,000 0,28535789 0,31529651 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,28535789 0,3151076 ! digestion GO:0007586 31 31 0,000 0,28535789 0,31491891 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,28535789 0,31473045 ! regulation of heart contraction GO:0008016 31 31 0,000 0,28535789 0,31454222 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,28535789 0,31435421 ! camera-type eye development GO:0043010 31 31 0,000 0,28535789 0,31416642 ! extracellular matrix organization GO:0030198 31 31 0,000 0,28535789 0,31397886 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,28535789 0,31379152 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,28535789 0,3136044 ! regulation of myeloid cell differentiation GO:0045637 32 31 0,000 0,28535789 0,31341751 ! response to other organism GO:0051707 101 100 1,000 0,29233721 0,32089189 ! cell redox homeostasis GO:0045454 32 32 0,000 0,29307924 0,3215149 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,29307924 0,32132363 ! cell maturation GO:0048469 32 32 0,000 0,29307924 0,3211326 ! morphogenesis of a branching structure GO:0001763 32 32 0,000 0,29307924 0,32094179 ! nuclear export GO:0051168 32 32 0,000 0,29307924 0,32075121 ! kidney development GO:0001822 32 32 0,000 0,29307924 0,32056085 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,29307924 0,32037072 ! maintenance of location GO:0051235 33 32 0,000 0,29307924 0,32018081 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,30071827 0,32833162 ! regulation of neuron differentiation GO:0045664 34 33 0,000 0,30071827 0,32813723 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,30071827 0,32794306 ! response to metal ion GO:0010038 34 34 0,000 0,30827587 0,33598606 ! ear development GO:0043583 34 34 0,000 0,30827587 0,33578749 ! muscle cell differentiation GO:0042692 35 34 0,000 0,30827587 0,33558915 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,30827587 0,33539104 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,30827587 0,33519317 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,30827587 0,33499553 ! detection of stimulus GO:0051606 36 34 0,000 0,30827587 0,33479813 ! acute inflammatory response GO:0002526 35 35 0,000 0,31575287 0,34271646 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,31575287 0,34251474 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,31575287 0,34231326 GO:0048609|reproductive process in a multicellular organism, ! inorganic anion transport GO:0015698 35 35 0,000 0,31575287 0,34211202 ! regulation of immune effector process GO:0002697 35 35 0,000 0,31575287 0,34191102 ! hydrogen transport GO:0006818 36 36 0,000 0,32315014 0,34971562 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,32315014 0,34951039 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,32315014 0,3493054 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,32315014 0,34910065 ! female pregnancy GO:0007565 37 36 0,000 0,32315014 0,34889614 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,32315014 0,34869187 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,32315014 0,34848783 ! activation of immune response GO:0002253 36 36 0,000 0,32315014 0,34828404 ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,33046851 0,35596345 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,33046851 0,35575552 ! eye development GO:0001654 37 37 0,000 0,33046851 0,35554784 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,33046851 0,35534041 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,33046851 0,35513321 ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,33046851 0,35492626 ! positive regulation of secretion GO:0051047 39 38 0,000 0,3377088 0,36249116 ! neurotransmitter transport GO:0006836 40 38 0,000 0,3377088 0,36228016 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,3377088 0,36206941 ! regulation of neurological system process GO:0031644 38 38 0,000 0,3377088 0,36185891 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,34487184 0,36931947 ! response to unfolded protein GO:0006986 39 39 0,000 0,34487184 0,369105 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,34487184 0,36889078 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,34487184 0,3686768 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,34487184 0,36846308 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,34487184 0,3682496 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,34487184 0,36803637 ! developmental maturation GO:0021700 39 39 0,000 0,34487184 0,36782338 ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,35195845 0,3751645 ! DNA catabolic process GO:0006308 41 40 0,000 0,35195845 0,37494765 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,35195845 0,37473104 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,35896943 0,38197497 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! amine catabolic process GO:0009310 42 41 0,000 0,35896943 0,38175456 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,35896943 0,3815344 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,35896943 0,3813145 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,35896943 0,38109485 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,35896943 0,38087545 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,36590557 0,38801148 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,36590557 0,38778836 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,36590557 0,38756549 ! protein ubiquitination GO:0016567 43 42 0,000 0,36590557 0,38734288 ! response to protein stimulus GO:0051789 42 42 0,000 0,36590557 0,38712053 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,36590557 0,38689843 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,37276766 0,39392821 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,37276766 0,39370246 ! humoral immune response GO:0006959 44 44 0,000 0,37955648 0,40064296 ! mRNA transport GO:0051028 44 44 0,000 0,37955648 0,40041362 ! vitamin metabolic process GO:0006766 44 44 0,000 0,37955648 0,40018455 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,37955648 0,39995575 ! protein processing GO:0016485 45 45 0,000 0,38627281 0,40680045 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,39291741 0,41356184 ! tube morphogenesis GO:0035239 47 46 0,000 0,39291741 0,41332579 ! regulation of blood pressure GO:0008217 48 47 0,000 0,39949103 0,42000112 ! rhythmic process GO:0048511 47 47 0,000 0,39949103 0,41976167 ! calcium ion transport GO:0006816 48 48 0,000 0,40599442 0,42635197 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,41242832 0,43286184 ! divalent metal ion transport GO:0070838 49 49 0,000 0,41242832 0,43261548 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,41242832 0,43236939 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,41242832 0,43212359 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,41879346 0,43854338 ! chromatin assembly GO:0031497 50 50 0,000 0,41879346 0,43829435 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,41879346 0,4380456 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 0,000 0,41879346 0,43779714 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,41879346 0,43754895 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,42509058 0,44387645 ! protein modification by small protein conjugation GO:0032446 52 51 0,000 0,42509058 0,4436251 ! positive regulation of immune response GO:0050778 51 51 0,000 0,42509058 0,44337404 ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,42509058 0,44312327 ! ATP biosynthetic process GO:0006754 51 51 0,000 0,42509058 0,44287277 ! protein maturation GO:0051604 51 51 0,000 0,42509058 0,44262256 ! RNA localization GO:0006403 52 52 0,000 0,43132038 0,4488557 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,43132038 0,4486024 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 0,000 0,43132038 0,44834938 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,43132038 0,44809665 ! sodium ion transport GO:0006814 53 53 0,000 0,43748357 0,4542435 ! tRNA metabolic process GO:0006399 53 53 0,000 0,43748357 0,45398774 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,43748357 0,45373226 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,43748357 0,45347706 ! response to virus GO:0009615 54 54 0,000 0,44358086 0,4595388 ! hormone metabolic process GO:0042445 55 54 0,000 0,44358086 0,45928063 ! nucleosome organization GO:0034728 55 55 0,000 0,44961295 0,46526483 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,44961295 0,46500374 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! protein modification by small protein conjugation or removal GO:0070647 56 55 0,000 0,44961295 0,46474294 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,45558051 0,47064736 ! ATP metabolic process GO:0046034 57 57 0,000 0,46148424 0,47647925 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,46148424 0,47621246 ! innate immune response GO:0045087 58 58 0,000 0,46732481 0,48196957 ! sterol metabolic process GO:0016125 59 59 0,000 0,47310287 0,48765581 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,47310287 0,48738323 ! immune effector process GO:0002252 59 59 0,000 0,47310287 0,48711095 ! potassium ion transport GO:0006813 60 60 0,000 0,4788191 0,49272116 ! protein polymerization GO:0051258 65 60 0,000 0,4788191 0,49244621 ! cellular respiration GO:0045333 62 61 0,000 0,48447414 0,4979843 ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,48447414 0,49770671 GO:0016054|organic acid catabolic process, ! lipid transport GO:0006869 62 62 0,000 0,49006864 0,50317354 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,49006864 0,50289338 ! morphogenesis of an epithelium GO:0002009 63 62 0,000 0,49006864 0,50261353 GO:0060429|epithelium development, ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,49006864 0,50233399 ! regulation of secretion GO:0051046 65 63 0,000 0,49560325 0,50772473 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,49560325 0,50744266 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,49560325 0,5071609 ! anion transport GO:0006820 65 65 0,000 0,50649528 0,51801931 ! regulation of hormone levels GO:0010817 66 65 0,000 0,50649528 0,517732 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,51185395 0,52291953 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,51185395 0,52262982 ! DNA packaging GO:0006323 66 66 0,000 0,51185395 0,52234044 ! Golgi vesicle transport GO:0048193 67 67 0,000 0,51715521 0,52745825 ! muscle contraction GO:0006936 67 67 0,000 0,51715521 0,52716651 ! Ras protein signal transduction GO:0007265 69 67 0,000 0,51715521 0,5268751 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,52239967 0,53192409 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,52239967 0,53163037 ! sensory perception of sound GO:0007605 71 69 0,000 0,52758793 0,53661399 GO:0050954|sensory perception of mechanical stimulus, ! oxidative phosphorylation GO:0006119 71 71 0,000 0,53779822 0,54669725 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,53779822 0,54639587 GO:0006874|cellular calcium ion homeostasis, ! muscle system process GO:0003012 72 72 0,000 0,54282141 0,55119552 ! sensory organ development GO:0007423 72 72 0,000 0,54282141 0,55089199 ! regulation of cytokine production GO:0001817 72 72 0,000 0,54282141 0,55058881 ! electron transport chain GO:0022900 75 74 0,000 0,55270678 0,56030726 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,55270678 0,55999923 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,5575701 0,56461631 ! response to oxidative stress GO:0006979 76 75 0,000 0,5575701 0,56430625 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,5575701 0,56399653 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,56714076 0,57336282 ! microtubule-based movement GO:0007018 82 78 0,000 0,57184921 0,57780597 ! metal ion homeostasis GO:0055065 78 78 0,000 0,57184921 0,57748936 ! regulation of immune response GO:0050776 78 78 0,000 0,57184921 0,57717311 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,58111505 0,58620418 ! lipid catabolic process GO:0016042 82 81 0,000 0,5856735 0,59047936 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,5946441 0,59919577 ! positive regulation of cell differentiation GO:0045597 87 85 0,000 0,60342304 0,60770965 ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,61624091 0,62027963 ! chemotaxis GO:0006935 90 89 0,000 0,62042203 0,62414727 GO:0042330|taxis, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 0,000 0,62042203 0,62380677 ! regulation of Ras protein signal transduction GO:0046578 90 90 0,000 0,62455821 0,62762311 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 0,000 0,62864992 0,63139062 ! visual perception GO:0007601 93 92 0,000 0,63269763 0,63510987 GO:0050953|sensory perception of light stimulus, ! tissue morphogenesis GO:0048729 94 93 0,000 0,63670181 0,6387814 ! epidermis development GO:0008544 94 94 0,000 0,64066292 0,64240575 ! cofactor metabolic process GO:0051186 95 94 0,000 0,64066292 0,64205642 ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,65608575 0,65715546 ! regulation of system process GO:0044057 98 98 0,000 0,65608575 0,6567985 ! anti-apoptosis GO:0006916 100 99 0,000 0,65983828 0,6601965 ! ectoderm development GO:0007398 99 99 0,000 0,65983828 0,65983828