pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6306-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! negative regulation of cell-matrix adhesion GO:0001953 37 11 4,000 1,168E-08 2,852E-05 GO:0010812|negative regulation of cell-substrate adhesion, ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 7,000 1,342E-08 1,639E-05 ! cellular response to insulin stimulus GO:0032869 85 38 6,000 1,542E-08 1,255E-05 ! phospholipid dephosphorylation GO:0046839 12 5 3,000 1,717E-08 1,049E-05 ! negative regulation of phosphorylation GO:0042326 52 24 5,000 2,38E-08 1,163E-05 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 5,000 4,018E-08 1,636E-05 GO:0045936|negative regulation of phosphate metabolic process, ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 3,000 5,12E-08 1,787E-05 ! insulin receptor signaling pathway GO:0008286 66 27 5,000 5,133E-08 1,568E-05 ! response to insulin stimulus GO:0032868 98 47 6,000 7,241E-08 1,965E-05 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 3,000 1,187E-07 2,901E-05 ! negative regulation of focal adhesion formation GO:0051895 21 7 3,000 1,187E-07 2,637E-05 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 4,000 1,506E-07 3,065E-05 ! regulation of focal adhesion formation GO:0051893 23 8 3,000 2,36E-07 4,436E-05 ! cellular response to hormone stimulus GO:0032870 182 85 7,000 3,244E-07 5,661E-05 ! induction of positive chemotaxis GO:0050930 17 9 3,000 4,223E-07 6,878E-05 ! regulation of protein stability GO:0031647 77 38 5,000 4,459E-07 6,808E-05 ! response to peptide hormone stimulus GO:0043434 129 64 6,000 6,396E-07 9,192E-05 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 3,000 6,995E-07 9,494E-05 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 3,000 6,995E-07 8,994E-05 ! regulation of cell-matrix adhesion GO:0001952 81 23 4,000 7,883E-07 9,629E-05 GO:0010810|regulation of cell-substrate adhesion, ! negative regulation of protein kinase activity GO:0006469 144 69 6,000 1,075E-06 1,251E-04 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 3,000 1,093E-06 1,213E-04 ! negative regulation of glucose import GO:0046325 18 11 3,000 1,093E-06 1,161E-04 GO:0010829|negative regulation of glucose transport, ! negative regulation of kinase activity GO:0033673 145 70 6,000 1,187E-06 1,208E-04 ! induction of apoptosis by intracellular signals GO:0008629 95 45 5,000 1,257E-06 1,229E-04 ! negative regulation of cell migration GO:0030336 122 46 5,000 1,437E-06 1,35E-04 ! regulation of positive chemotaxis GO:0050926 22 12 3,000 1,629E-06 1,474E-04 GO:0050927|positive regulation of positive chemotaxis, ! negative regulation of transferase activity GO:0051348 155 74 6,000 1,735E-06 1,514E-04 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 3,000 3,254E-06 2,741E-04 ! negative regulation of cell motion GO:0051271 142 55 5,000 4,195E-06 3,416E-04 ! phospholipid scrambling GO:0017121 8 5 2,000 4,48E-06 3,53E-04 ! regulation of cell adhesion GO:0030155 241 92 6,000 7,508E-06 5,732E-04 ! endothelial cell migration GO:0043542 31 17 3,000 7,597E-06 5,624E-04 ! activation of MAPKK activity GO:0000186 43 17 3,000 7,597E-06 5,459E-04 ! cardiac muscle tissue development GO:0048738 34 17 3,000 7,597E-06 5,303E-04 ! activation of MAPKKK activity GO:0000185 12 6 2,000 8,908E-06 6,045E-04 ! L-serine biosynthetic process GO:0006564 7 6 2,000 8,908E-06 5,882E-04 ! negative regulation of cell adhesion GO:0007162 94 37 4,000 9,349E-06 6,011E-04 ! androgen receptor signaling pathway GO:0030521 81 37 4,000 9,349E-06 5,856E-04 ! inositol metabolic process GO:0006020 33 19 3,000 1,222E-05 7,465E-04 ! regulation of glucose import GO:0046324 30 20 3,000 1,519E-05 9,049E-04 GO:0010827|regulation of glucose transport, ! positive regulation of locomotion GO:0040017 44 22 3,000 2,265E-05 1,318E-03 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! regulation of caspase activity GO:0043281 136 74 5,000 2,372E-05 1,348E-03 ! ER overload response GO:0006983 13 8 2,000 2,466E-05 1,369E-03 ! regulation of T cell differentiation in the thymus GO:0033081 14 8 2,000 2,466E-05 1,339E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 2,000 2,466E-05 1,31E-03 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 2,000 2,466E-05 1,282E-03 ! regulation of chemotaxis GO:0050920 45 23 3,000 2,726E-05 1,387E-03 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 4,000 2,778E-05 1,385E-03 ! regulation of endopeptidase activity GO:0052548 141 77 5,000 2,978E-05 1,455E-03 ! sex determination GO:0007530 48 24 3,000 3,251E-05 1,557E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 2,000 3,678E-05 1,728E-03 ! activation of protein kinase activity GO:0032147 170 80 5,000 3,702E-05 1,707E-03 ! vasculogenesis GO:0001570 49 25 3,000 3,847E-05 1,74E-03 ! regulation of behavior GO:0050795 48 25 3,000 3,847E-05 1,709E-03 ! positive regulation of phosphorylation GO:0042327 149 81 5,000 3,973E-05 1,733E-03 ! regulation of peptidase activity GO:0052547 150 82 5,000 4,259E-05 1,825E-03 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 3,000 4,519E-05 1,903E-03 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 5,000 4,561E-05 1,889E-03 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of developmental growth GO:0048638 16 10 2,000 5,224E-05 2,127E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 2,000 5,224E-05 2,092E-03 ! motor axon guidance GO:0008045 22 10 2,000 5,224E-05 2,058E-03 ! negative regulation of protein modification process GO:0031400 66 28 3,000 6,114E-05 2,371E-03 ! peptidyl-tyrosine modification GO:0018212 57 28 3,000 6,114E-05 2,334E-03 ! L-serine metabolic process GO:0006563 21 11 2,000 7,142E-05 2,684E-03 ! chondrocyte differentiation GO:0002062 27 11 2,000 7,142E-05 2,644E-03 ! regulation of embryonic development GO:0045995 35 11 2,000 7,142E-05 2,604E-03 ! positive regulation of protein modification process GO:0031401 156 90 5,000 7,194E-05 2,584E-03 ! negative regulation of protein kinase cascade GO:0010741 72 30 3,000 8,085E-05 2,862E-03 ! positive regulation of MAP kinase activity GO:0043406 174 93 5,000 8,639E-05 3,015E-03 ! regulation of B cell proliferation GO:0030888 22 12 2,000 9,468E-05 3,258E-03 ! negative regulation of mast cell proliferation GO:0070667 24 12 2,000 9,468E-05 3,213E-03 GO:0042130|negative regulation of T cell proliferation, ! lipid modification GO:0030258 112 60 4,000 1,014E-04 3,393E-03 ! interphase of mitotic cell cycle GO:0051329 224 98 5,000 1,155E-04 3,814E-03 ! plasma membrane organization GO:0007009 27 13 2,000 1,224E-04 3,986E-03 ! serine family amino acid metabolic process GO:0009069 56 34 3,000 1,335E-04 4,292E-03 ! serine family amino acid biosynthetic process GO:0009070 19 14 2,000 1,549E-04 4,914E-03 ! steroid hormone receptor signaling pathway GO:0030518 146 66 4,000 1,598E-04 5,004E-03 ! negative regulation of cell growth GO:0030308 142 67 4,000 1,716E-04 5,306E-03 ! negative regulation of bone remodeling GO:0046851 34 15 2,000 1,925E-04 5,878E-03 ! regulation of the force of heart contraction GO:0002026 31 15 2,000 1,925E-04 5,806E-03 ! epithelial to mesenchymal transition GO:0001837 30 15 2,000 1,925E-04 5,735E-03 ! negative regulation of cell size GO:0045792 144 69 4,000 1,972E-04 5,803E-03 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 4,000 1,972E-04 5,734E-03 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 4,000 2,256E-04 6,484E-03 ! fructose metabolic process GO:0006000 25 16 2,000 2,356E-04 6,692E-03 ! negative regulation of tissue remodeling GO:0034104 37 16 2,000 2,356E-04 6,615E-03 ! negative regulation of leukocyte proliferation GO:0070664 32 16 2,000 2,356E-04 6,539E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 4,000 2,739E-04 7,519E-03 ! negative regulation of cell cycle process GO:0010948 35 17 2,000 2,844E-04 7,72E-03 ! embryonic forelimb morphogenesis GO:0035115 31 17 2,000 2,844E-04 7,635E-03 ! neutrophil chemotaxis GO:0030593 29 17 2,000 2,844E-04 7,552E-03 ! phosphoinositide metabolic process GO:0030384 146 77 4,000 3,297E-04 8,661E-03 ! response to retinoic acid GO:0032526 31 18 2,000 3,393E-04 8,819E-03 ! cell-substrate junction assembly GO:0007044 56 18 2,000 3,393E-04 8,727E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 2,000 3,393E-04 8,636E-03 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 2,000 3,393E-04 8,547E-03 ! detection of bacterium GO:0016045 22 18 2,000 3,393E-04 8,459E-03 ! positive regulation of response to external stimulus GO:0032103 88 44 3,000 3,68E-04 9,08E-03 ! protein oligomerization GO:0051259 149 79 4,000 3,714E-04 9,074E-03 ! negative regulation of organelle organization GO:0010639 181 80 4,000 3,937E-04 9,523E-03 ! response to vitamin A GO:0033189 32 19 2,000 4,007E-04 9,597E-03 ! polyol metabolic process GO:0019751 77 45 3,000 4,014E-04 9,521E-03 ! glycolysis GO:0006096 71 46 3,000 4,37E-04 0,01026533 ! regulation of gene-specific transcription GO:0032583 102 46 3,000 4,37E-04 0,01016757 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 2,000 4,687E-04 0,01080247 ! response to vitamin GO:0033273 36 20 2,000 4,687E-04 0,01070151 ! regulation of carbohydrate metabolic process GO:0006109 37 20 2,000 4,687E-04 0,01060243 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 2,000 4,687E-04 0,01050516 ! apoptotic mitochondrial changes GO:0008637 42 20 2,000 4,687E-04 0,01040965 ! negative regulation of T cell activation GO:0050868 41 20 2,000 4,687E-04 0,01031587 ! negative regulation of translation GO:0017148 32 20 2,000 4,687E-04 0,01022377 ! positive regulation of cell cycle GO:0045787 96 48 3,000 5,148E-04 0,01113025 ! negative regulation of transport GO:0051051 164 85 4,000 5,207E-04 0,01115844 ! negative regulation of growth GO:0045926 168 85 4,000 5,207E-04 0,01106141 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 2,000 5,437E-04 0,01145098 ! positive regulation of inflammatory response GO:0050729 41 21 2,000 5,437E-04 0,01135311 ! regulation of mast cell proliferation GO:0070666 89 49 3,000 5,572E-04 0,01153626 ! negative regulation of bone resorption GO:0045779 10 5 1,000 5,831E-04 0,01197042 ! cell adhesion mediated by integrin GO:0033627 10 5 1,000 5,831E-04 0,01187066 ! hypothalamus development GO:0021854 9 5 1,000 5,831E-04 0,01177256 ! 2-oxoglutarate metabolic process GO:0006103 10 5 1,000 5,831E-04 0,01167606 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 1,000 5,831E-04 0,01158113 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 1,000 5,831E-04 0,01148774 ! positive regulation of glycolysis GO:0045821 13 5 1,000 5,831E-04 0,01139584 ! epithelial cell proliferation GO:0050673 9 5 1,000 5,831E-04 0,01130539 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 1,000 5,831E-04 0,01121637 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! microvillus organization GO:0032528 8 5 1,000 5,831E-04 0,01112875 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 1,000 5,831E-04 0,01104248 ! regulation of glycogen metabolic process GO:0070873 10 5 1,000 5,831E-04 0,01095753 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 5,831E-04 0,01087389 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 1,000 5,831E-04 0,01079151 ! regulation of centrosome cycle GO:0046605 7 5 1,000 5,831E-04 0,01071037 ! meiotic chromosome segregation GO:0045132 10 5 1,000 5,831E-04 0,01063044 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 5,831E-04 0,0105517 ! protein insertion into membrane GO:0051205 17 5 1,000 5,831E-04 0,01047411 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 1,000 5,831E-04 0,01039766 GO:0022011|myelination in the peripheral nervous system, ! stem cell division GO:0017145 11 5 1,000 5,831E-04 0,01032231 GO:0048103|somatic stem cell division, ! induction of apoptosis by extracellular signals GO:0008624 99 50 3,000 6,02E-04 0,01058097 ! activation of caspase activity GO:0006919 95 50 3,000 6,02E-04 0,0105054 ! hindlimb morphogenesis GO:0035137 47 22 2,000 6,26E-04 0,01084616 ! inactivation of MAPK activity GO:0000188 45 22 2,000 6,26E-04 0,01076978 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 2,000 6,26E-04 0,01069447 ! positive regulation of intracellular transport GO:0032388 42 22 2,000 6,26E-04 0,0106202 ! regulation of cell cycle process GO:0010564 161 90 4,000 6,762E-04 0,01139324 ! positive regulation of growth GO:0045927 96 53 3,000 7,518E-04 0,01257908 ! regulation of leukocyte proliferation GO:0070663 97 53 3,000 7,518E-04 0,01249351 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of angiogenesis GO:0045765 125 54 3,000 8,07E-04 0,01332133 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 2,000 8,134E-04 0,01333684 ! detection of biotic stimulus GO:0009595 34 24 2,000 8,134E-04 0,01324793 ! response to UV GO:0009411 120 55 3,000 8,651E-04 0,01399617 ! positive regulation of DNA repair GO:0045739 9 6 1,000 8,702E-04 0,01398578 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 1,000 8,702E-04 0,01389437 ! toxin metabolic process GO:0009404 11 6 1,000 8,702E-04 0,01380414 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 1,000 8,702E-04 0,01371508 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 1,000 8,702E-04 0,01362717 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 1,000 8,702E-04 0,01354037 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! establishment of spindle localization GO:0051293 16 6 1,000 8,702E-04 0,01345467 GO:0051653|spindle localization, ! astrocyte development GO:0014002 16 6 1,000 8,702E-04 0,01337005 ! Schwann cell development GO:0014044 15 6 1,000 8,702E-04 0,01328649 ! neutrophil homeostasis GO:0001780 11 6 1,000 8,702E-04 0,01320396 ! negative regulation of neuroblast proliferation GO:0007406 25 6 1,000 8,702E-04 0,01312246 ! negative regulation of B cell activation GO:0050869 14 6 1,000 8,702E-04 0,01304195 ! cellular anion homeostasis GO:0030002 11 6 1,000 8,702E-04 0,01296243 GO:0055081|anion homeostasis, ! protein import into nucleus, translocation GO:0000060 51 25 2,000 9,191E-04 0,01360821 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 2,000 9,191E-04 0,01352624 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 2,000 9,191E-04 0,01344524 ! protein tetramerization GO:0051262 57 25 2,000 9,191E-04 0,01336521 ! negative regulation of cytoskeleton organization GO:0051494 139 56 3,000 9,26E-04 0,01338657 ! glucose catabolic process GO:0006007 88 56 3,000 9,26E-04 0,01330782 ! regulation of DNA replication GO:0006275 105 56 3,000 9,26E-04 0,01323 ! regulation of DNA metabolic process GO:0051052 188 97 4,000 9,493E-04 0,01348284 ! positive regulation of caspase activity GO:0043280 108 57 3,000 9,9E-04 0,01397959 GO:0010952|positive regulation of peptidase activity, ! myelination GO:0042552 50 26 2,000 1,033E-03 0,01450476 ! response to endoplasmic reticulum stress GO:0034976 46 26 2,000 1,033E-03 0,01442188 ! positive regulation of cell migration GO:0030335 137 58 3,000 1,057E-03 0,01467062 ! negative regulation of lymphocyte activation GO:0051250 55 27 2,000 1,156E-03 0,01595032 ! positive regulation of protein ubiquitination GO:0031398 14 7 1,000 1,212E-03 0,01663498 ! regulation of helicase activity GO:0051095 16 7 1,000 1,212E-03 0,01654205 ! prostate gland development GO:0030850 14 7 1,000 1,212E-03 0,01645015 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 1,212E-03 0,01635926 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 1,212E-03 0,01626938 ! mRNA stabilization GO:0048255 18 7 1,000 1,212E-03 0,01618047 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 1,000 1,212E-03 0,01609254 ! oxaloacetate metabolic process GO:0006107 13 7 1,000 1,212E-03 0,01600555 ! male sex determination GO:0030238 15 7 1,000 1,212E-03 0,0159195 ! wound healing, spreading of epidermal cells GO:0035313 16 7 1,000 1,212E-03 0,01583437 ! G1 DNA damage checkpoint GO:0031571 20 7 1,000 1,212E-03 0,01575014 ! B cell lineage commitment GO:0002326 21 7 1,000 1,212E-03 0,01566681 ! T cell lineage commitment GO:0002360 16 7 1,000 1,212E-03 0,01558435 ! negative regulation of response to stimulus GO:0048585 106 61 3,000 1,277E-03 0,01633046 ! regulation of fibroblast proliferation GO:0048145 56 28 2,000 1,287E-03 0,01637536 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 2,000 1,287E-03 0,01629051 ! ER-nuclear signaling pathway GO:0006984 52 29 2,000 1,427E-03 0,0179741 ! mesoderm development GO:0007498 128 63 3,000 1,44E-03 0,01803965 ! protein amino acid autophosphorylation GO:0046777 157 64 3,000 1,527E-03 0,01902943 ! positive regulation of multicellular organism growth GO:0040018 55 30 2,000 1,577E-03 0,0195557 ! regulation of B cell activation GO:0050864 55 30 2,000 1,577E-03 0,01945693 ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 1,000 1,608E-03 0,01973847 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 1,000 1,608E-03 0,01963978 ! male meiosis GO:0007140 9 8 1,000 1,608E-03 0,01954207 ! succinate metabolic process GO:0006105 17 8 1,000 1,608E-03 0,01944532 ! T-helper 1 type immune response GO:0042088 12 8 1,000 1,608E-03 0,01934953 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 1,608E-03 0,01925468 ! astrocyte differentiation GO:0048708 19 8 1,000 1,608E-03 0,01916076 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 1,608E-03 0,01906775 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 1,608E-03 0,01897563 ! regulation of vascular permeability GO:0043114 12 8 1,000 1,608E-03 0,0188844 ! Schwann cell differentiation GO:0014037 21 8 1,000 1,608E-03 0,01879405 ! response to tumor cell GO:0002347 16 8 1,000 1,608E-03 0,01870455 ! regulation of respiratory burst GO:0060263 12 8 1,000 1,608E-03 0,0186159 ! myeloid cell homeostasis GO:0002262 15 8 1,000 1,608E-03 0,01852809 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 1,608E-03 0,01844111 ! positive regulation of cell motion GO:0051272 157 65 3,000 1,617E-03 0,01846047 ! cell junction assembly GO:0034329 85 31 2,000 1,736E-03 0,01972599 ! cellular response to extracellular stimulus GO:0031668 52 31 2,000 1,736E-03 0,01963466 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 2,000 1,736E-03 0,01954418 ! ensheathment of neurons GO:0007272 64 31 2,000 1,736E-03 0,01945453 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 60 31 2,000 1,736E-03 0,0193657 ! spindle organization GO:0007051 50 32 2,000 1,905E-03 0,02115152 ! peripheral nervous system development GO:0007422 68 32 2,000 1,905E-03 0,02105581 ! positive regulation of catabolic process GO:0009896 72 32 2,000 1,905E-03 0,02096096 ! hexose catabolic process GO:0019320 113 68 3,000 1,91E-03 0,02092879 ! urogenital system development GO:0001655 149 69 3,000 2,016E-03 0,02198521 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 2,057E-03 0,02233137 ! cell proliferation in forebrain GO:0021846 18 9 1,000 2,057E-03 0,02223256 ! regulation of glycolysis GO:0006110 20 9 1,000 2,057E-03 0,02213462 ! cerebral cortex cell migration GO:0021795 18 9 1,000 2,057E-03 0,02203754 ! microtubule bundle formation GO:0001578 22 9 1,000 2,057E-03 0,0219413 ! negative regulation of endocytosis GO:0045806 12 9 1,000 2,057E-03 0,02184591 ! glycine catabolic process GO:0006546 15 9 1,000 2,057E-03 0,02175134 ! regulation of Notch signaling pathway GO:0008593 24 9 1,000 2,057E-03 0,02165758 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 1,000 2,057E-03 0,02156463 ! postreplication repair GO:0006301 25 9 1,000 2,057E-03 0,02147247 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 1,000 2,057E-03 0,0213811 ! regulation of synaptogenesis GO:0051963 15 9 1,000 2,057E-03 0,0212905 ! leukocyte chemotaxis GO:0030595 55 33 2,000 2,083E-03 0,02147556 GO:0060326|cell chemotaxis, ! cell cycle checkpoint GO:0000075 145 71 3,000 2,239E-03 0,02297888 ! regulation of ARF GTPase activity GO:0032312 73 34 2,000 2,272E-03 0,02322464 ! negative regulation of MAP kinase activity GO:0043407 78 34 2,000 2,272E-03 0,02312787 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 2,000 2,272E-03 0,02303191 ! regulation of striated muscle tissue development GO:0016202 81 35 2,000 2,471E-03 0,02494523 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 1,000 2,558E-03 0,0257152 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 2,558E-03 0,02560981 ! SMAD protein nuclear translocation GO:0007184 21 10 1,000 2,558E-03 0,02550528 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 2,558E-03 0,0254016 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 1,000 2,558E-03 0,02529876 ! lung alveolus development GO:0048286 26 10 1,000 2,558E-03 0,02519675 ! pathogenesis GO:0009405 17 10 1,000 2,558E-03 0,02509556 ! negative regulation of striated muscle development GO:0045843 26 10 1,000 2,558E-03 0,02499518 ! phosphagen metabolic process GO:0006599 17 10 1,000 2,558E-03 0,02489559 GO:0006600|creatine metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 1,000 2,558E-03 0,0247968 ! regulation of bone resorption GO:0045124 25 10 1,000 2,558E-03 0,02469879 ! protein heterooligomerization GO:0051291 17 10 1,000 2,558E-03 0,02460155 ! DNA ligation GO:0006266 18 10 1,000 2,558E-03 0,02450507 ! regulation of fat cell differentiation GO:0045598 18 10 1,000 2,558E-03 0,02440935 ! serine family amino acid catabolic process GO:0009071 18 10 1,000 2,558E-03 0,02431437 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 1,000 2,558E-03 0,02422013 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 2,558E-03 0,02412662 ! regulation of muscle development GO:0048634 82 36 2,000 2,68E-03 0,02518586 ! reproductive structure development GO:0048608 131 75 3,000 2,734E-03 0,02559095 ! axon guidance GO:0007411 162 75 3,000 2,734E-03 0,02549328 ! regulation of smooth muscle cell proliferation GO:0048660 64 37 2,000 2,9E-03 0,02694244 ! cell junction organization GO:0034330 96 37 2,000 2,9E-03 0,02684038 ! tissue remodeling GO:0048771 78 37 2,000 2,9E-03 0,0267391 ! regulation of microtubule-based process GO:0032886 86 37 2,000 2,9E-03 0,02663858 ! negative regulation of cell activation GO:0050866 69 37 2,000 2,9E-03 0,02653881 ! monosaccharide catabolic process GO:0046365 125 77 3,000 3,008E-03 0,02741819 ! negative regulation of muscle development GO:0048635 27 11 1,000 3,11E-03 0,02824774 ! telencephalon cell migration GO:0022029 23 11 1,000 3,11E-03 0,02814312 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 1,000 3,11E-03 0,02803927 ! blood vessel remodeling GO:0001974 30 11 1,000 3,11E-03 0,02793619 ! positive regulation of endothelial cell proliferation GO:0001938 23 11 1,000 3,11E-03 0,02783386 ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 3,11E-03 0,02773227 ! regulation of intracellular pH GO:0051453 21 11 1,000 3,11E-03 0,02763143 ! negative regulation of ossification GO:0030279 27 11 1,000 3,11E-03 0,02753132 ! positive regulation of leukocyte migration GO:0002687 28 11 1,000 3,11E-03 0,02743193 ! positive regulation of DNA metabolic process GO:0051054 77 38 2,000 3,131E-03 0,02751719 ! glycogen metabolic process GO:0005977 63 38 2,000 3,131E-03 0,02741856 ! steroid biosynthetic process GO:0006694 146 79 3,000 3,3E-03 0,02879021 ! glucan metabolic process GO:0044042 64 39 2,000 3,373E-03 0,02932556 GO:0006073|cellular glucan metabolic process, ! meiosis GO:0007126 143 81 3,000 3,61E-03 0,03127718 GO:0051327|M phase of meiotic cell cycle, ! regulation of action potential in neuron GO:0019228 80 40 2,000 3,626E-03 0,03130163 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 1,000 3,714E-03 0,03194405 ! positive regulation of cellular catabolic process GO:0031331 34 12 1,000 3,714E-03 0,03183197 ! virus-host interaction GO:0019048 30 12 1,000 3,714E-03 0,03172067 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 1,000 3,714E-03 0,03161014 ! focal adhesion formation GO:0048041 37 12 1,000 3,714E-03 0,03150039 ! forebrain cell migration GO:0021885 24 12 1,000 3,714E-03 0,03139139 ! histone acetylation GO:0016573 27 12 1,000 3,714E-03 0,03128314 ! peptidyl-lysine modification GO:0018205 21 12 1,000 3,714E-03 0,03117564 ! regulation of leukocyte migration GO:0002685 29 12 1,000 3,714E-03 0,03106887 ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 1,000 3,714E-03 0,03096284 ! regulation of synapse organization GO:0050807 18 12 1,000 3,714E-03 0,03085752 ! localization within membrane GO:0051668 26 12 1,000 3,714E-03 0,03075292 ! meiotic cell cycle GO:0051321 144 82 3,000 3,773E-03 0,03113916 ! mesenchymal cell development GO:0014031 94 41 2,000 3,89E-03 0,03199932 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of intracellular protein transport GO:0033157 86 42 2,000 4,166E-03 0,03415152 ! T cell differentiation GO:0030217 93 42 2,000 4,166E-03 0,0340373 ! regulation of T cell differentiation GO:0045580 78 42 2,000 4,166E-03 0,03392384 ! hemostasis GO:0007599 165 85 3,000 4,29E-03 0,03481917 ! double-strand break repair via homologous recombination GO:0000724 19 13 1,000 4,366E-03 0,03532194 GO:0000725|recombinational repair, ! negative regulation of lipid metabolic process GO:0045833 20 13 1,000 4,366E-03 0,03520537 ! regulation of skeletal muscle fiber development GO:0048742 32 13 1,000 4,366E-03 0,03508956 ! response to X-ray GO:0010165 28 13 1,000 4,366E-03 0,03497451 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 1,000 4,366E-03 0,03486022 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of DNA repair GO:0006282 23 13 1,000 4,366E-03 0,03474666 ! nucleoside triphosphate catabolic process GO:0009143 22 13 1,000 4,366E-03 0,03463385 ! regulation of monooxygenase activity GO:0032768 35 13 1,000 4,366E-03 0,03452177 ! regulation of mRNA stability GO:0043488 32 13 1,000 4,366E-03 0,03441041 ! regulation of synapse structure and activity GO:0050803 19 13 1,000 4,366E-03 0,03429976 ! regulation of T cell proliferation GO:0042129 80 43 2,000 4,453E-03 0,03486788 ! neuron migration GO:0001764 85 43 2,000 4,453E-03 0,03475648 ! alcohol catabolic process GO:0046164 142 87 3,000 4,66E-03 0,03625706 ! energy reserve metabolic process GO:0006112 76 44 2,000 4,752E-03 0,03685401 ! negative regulation of protein complex disassembly GO:0043242 113 44 2,000 4,752E-03 0,03673738 ! double-strand break repair GO:0006302 85 44 2,000 4,752E-03 0,03662149 ! regulation of epithelial cell proliferation GO:0050678 122 45 2,000 5,063E-03 0,03889365 ! lipid localization GO:0010876 32 14 1,000 5,068E-03 0,03881517 GO:0019915|lipid storage, ! regulation of cellular pH GO:0030641 27 14 1,000 5,068E-03 0,03869387 ! response to gamma radiation GO:0010332 30 14 1,000 5,068E-03 0,03857333 ! regulation of RNA stability GO:0043487 33 14 1,000 5,068E-03 0,03845354 ! release of cytochrome c from mitochondria GO:0001836 31 14 1,000 5,068E-03 0,03833448 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 2,000 5,385E-03 0,04060677 ! leukocyte migration GO:0050900 75 46 2,000 5,385E-03 0,04048183 ! positive regulation of protein transport GO:0051222 80 46 2,000 5,385E-03 0,04035765 ! gland development GO:0048732 220 91 3,000 5,463E-03 0,04081751 ! regulation of skeletal muscle tissue development GO:0048641 35 15 1,000 5,819E-03 0,04333726 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 5,819E-03 0,04320554 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 1,000 5,819E-03 0,04307461 ! G1/S transition checkpoint GO:0031575 37 15 1,000 5,819E-03 0,04294448 ! muscle maintenance GO:0046716 26 15 1,000 5,819E-03 0,04281513 ! regulation of cell morphogenesis GO:0022604 243 93 3,000 5,898E-03 0,04326812 ! positive regulation of defense response GO:0031349 88 48 2,000 6,067E-03 0,04437827 ! male sex differentiation GO:0046661 93 48 2,000 6,067E-03 0,04424579 ! regulation of inflammatory response GO:0050727 84 48 2,000 6,067E-03 0,04411411 ! regulation of lymphocyte differentiation GO:0045619 92 49 2,000 6,427E-03 0,04658824 ! sex differentiation GO:0007548 171 96 3,000 6,591E-03 0,04764108 ! regulation of protein ubiquitination GO:0031396 28 16 1,000 6,616E-03 0,04767868 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 6,616E-03 0,04753845 ! embryonic hindlimb morphogenesis GO:0035116 36 16 1,000 6,616E-03 0,04739904 ! bone remodeling GO:0046849 28 16 1,000 6,616E-03 0,04726044 ! heterophilic cell adhesion GO:0007157 43 16 1,000 6,616E-03 0,04712266 ! pituitary gland development GO:0021983 30 16 1,000 6,616E-03 0,04698567 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 1,000 6,616E-03 0,04684948 ! positive regulation of protein import into nucleus GO:0042307 34 16 1,000 6,616E-03 0,04671408 ! DNA replication initiation GO:0006270 28 16 1,000 6,616E-03 0,04657946 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 6,616E-03 0,04644561 ! regulation of action potential GO:0001508 102 50 2,000 6,798E-03 0,04758883 ! regulation of ARF protein signal transduction GO:0032012 115 50 2,000 6,798E-03 0,04745286 ! regulation of gene expression, epigenetic GO:0040029 116 50 2,000 6,798E-03 0,04731767 ! forebrain development GO:0030900 210 98 3,000 7,083E-03 0,04915522 ! negative regulation of immune system process GO:0002683 101 51 2,000 7,183E-03 0,04970931 ! filopodium assembly GO:0046847 42 17 1,000 7,46E-03 0,05148448 ! glial cell development GO:0021782 28 17 1,000 7,46E-03 0,05133946 ! induction of apoptosis via death domain receptors GO:0008625 23 17 1,000 7,46E-03 0,05119525 ! negative regulation of microtubule depolymerization GO:0007026 50 17 1,000 7,46E-03 0,05105184 GO:0031114|regulation of microtubule depolymerization, ! DNA unwinding during replication GO:0006268 26 17 1,000 7,46E-03 0,05090924 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 1,000 7,46E-03 0,05076743 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 1,000 7,46E-03 0,05062641 ! branched chain family amino acid metabolic process GO:0009081 37 17 1,000 7,46E-03 0,05048617 ! negative regulation of homeostatic process GO:0032845 36 17 1,000 7,46E-03 0,05034671 ! regulation of protein complex disassembly GO:0043244 127 52 2,000 7,58E-03 0,05101138 ! cellular amino acid biosynthetic process GO:0008652 80 52 2,000 7,58E-03 0,05087124 ! DNA-dependent DNA replication GO:0006261 82 52 2,000 7,58E-03 0,05073187 ! cartilage development GO:0051216 99 53 2,000 7,989E-03 0,05332778 ! limbic system development GO:0021761 40 18 1,000 8,35E-03 0,05558602 ! centrosome cycle GO:0007098 26 18 1,000 8,35E-03 0,05543497 ! positive regulation of proteolysis GO:0045862 36 18 1,000 8,35E-03 0,05528474 ! glycine metabolic process GO:0006544 30 18 1,000 8,35E-03 0,05513532 ! microspike assembly GO:0030035 46 18 1,000 8,35E-03 0,05498671 ! positive regulation of synaptic transmission GO:0050806 35 18 1,000 8,35E-03 0,05483889 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 1,000 8,35E-03 0,05469187 ! regulation of muscle contraction GO:0006937 94 54 2,000 8,412E-03 0,05494682 ! regulation of cell shape GO:0008360 142 54 2,000 8,412E-03 0,05480029 ! regulation of multicellular organism growth GO:0040014 90 55 2,000 8,847E-03 0,05748342 ! G1 phase of mitotic cell cycle GO:0000080 39 19 1,000 9,286E-03 0,06017219 ! regulation of lipid biosynthetic process GO:0046890 28 19 1,000 9,286E-03 0,060013 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 1,000 9,286E-03 0,05985466 ! memory GO:0007613 34 19 1,000 9,286E-03 0,05969714 ! cerebral cortex development GO:0021987 40 19 1,000 9,286E-03 0,05954046 ! pigmentation during development GO:0048066 42 19 1,000 9,286E-03 0,05938459 ! neuromuscular junction development GO:0007528 43 19 1,000 9,286E-03 0,05922954 ! regulation of endothelial cell migration GO:0010594 45 19 1,000 9,286E-03 0,0590753 ! peptide cross-linking GO:0018149 39 19 1,000 9,286E-03 0,05892186 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 1,000 9,286E-03 0,05876921 ! regulation of bone remodeling GO:0046850 143 57 2,000 9,757E-03 0,06159273 ! nucleotide-excision repair GO:0006289 91 57 2,000 9,757E-03 0,06143399 ! regulation of intracellular transport GO:0032386 108 57 2,000 9,757E-03 0,06127606 ! cellular polysaccharide metabolic process GO:0044264 93 58 2,000 0,01023157 0,06409158 ! aging GO:0007568 112 58 2,000 0,01023157 0,06392766 ! regulation of tissue remodeling GO:0034103 146 58 2,000 0,01023157 0,06376458 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 0,01026534 0,06381229 ! protein amino acid acetylation GO:0006473 41 20 1,000 0,01026534 0,06365033 ! DNA duplex unwinding GO:0032508 30 20 1,000 0,01026534 0,06348919 GO:0032392|DNA geometric change, ! peptidyl-serine phosphorylation GO:0018105 44 20 1,000 0,01026534 0,06332887 ! actin filament bundle formation GO:0051017 47 20 1,000 0,01026534 0,06316935 ! regulation of fatty acid metabolic process GO:0019217 45 20 1,000 0,01026534 0,06301063 ! positive regulation of neurological system process GO:0031646 39 20 1,000 0,01026534 0,06285271 ! lipid phosphorylation GO:0046834 43 21 1,000 0,01128867 0,06894556 ! cell structure disassembly during apoptosis GO:0006921 32 21 1,000 0,01128867 0,06877362 ! plasma membrane fusion GO:0045026 33 21 1,000 0,01128867 0,06860255 ! diencephalon development GO:0021536 36 21 1,000 0,01128867 0,06843232 ! negative regulation of angiogenesis GO:0016525 49 21 1,000 0,01128867 0,06826293 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 1,000 0,01128867 0,06809438 ! regulation of heart contraction GO:0008016 123 61 2,000 0,01173464 0,07061015 ! DNA damage response, signal transduction GO:0042770 136 62 2,000 0,01226233 0,07360413 ! positive regulation of protein catabolic process GO:0045732 44 22 1,000 0,01235494 0,07397822 ! cellular response to starvation GO:0009267 37 22 1,000 0,01235494 0,07379735 ! apoptotic nuclear changes GO:0030262 34 22 1,000 0,01235494 0,07361735 ! cell aging GO:0007569 48 22 1,000 0,01235494 0,07343823 ! G1 phase GO:0051318 44 22 1,000 0,01235494 0,07325999 ! peptidyl-serine modification GO:0018209 50 22 1,000 0,01235494 0,0730826 ! positive regulation of B cell activation GO:0050871 42 22 1,000 0,01235494 0,07290607 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 1,000 0,01235494 0,0727304 ! regulation of mitosis GO:0007088 112 63 2,000 0,01280345 0,07518952 GO:0051783|regulation of nuclear division, ! regulation of bone mineralization GO:0030500 54 23 1,000 0,01346343 0,07887567 ! positive regulation of DNA replication GO:0045740 44 23 1,000 0,01346343 0,07868697 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 1,000 0,01346343 0,07849917 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 1,000 0,01346343 0,07831227 ! gonad development GO:0008406 115 66 2,000 0,01450783 0,08418676 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 1,000 0,01461343 0,08459859 ! positive regulation of cell adhesion GO:0045785 61 24 1,000 0,01461343 0,08439859 ! regulation of cellular catabolic process GO:0031329 55 24 1,000 0,01461343 0,08419954 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 1,000 0,01461343 0,08400142 ! barbed-end actin filament capping GO:0051016 58 24 1,000 0,01461343 0,08380423 GO:0051693|actin filament capping, ! pallium development GO:0021543 56 24 1,000 0,01461343 0,08360797 ! regulation of oxidoreductase activity GO:0051341 48 24 1,000 0,01461343 0,08341263 ! platelet activation GO:0030168 41 24 1,000 0,01461343 0,08321819 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 1,000 0,01461343 0,08302466 ! activation of MAPK activity GO:0000187 124 67 2,000 0,01510309 0,08560755 ! embryonic limb morphogenesis GO:0030326 139 67 2,000 0,01510309 0,08540939 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 2,000 0,01510309 0,08521214 ! negative regulation of ligase activity GO:0051352 116 68 2,000 0,01571199 0,08844328 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 2,000 0,01571199 0,08823996 ! cell projection assembly GO:0030031 138 68 2,000 0,01571199 0,08803757 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 0,01580424 0,08835184 ! leukocyte adhesion GO:0007159 55 25 1,000 0,01580424 0,08815013 ! dicarboxylic acid metabolic process GO:0043648 48 25 1,000 0,01580424 0,08794933 ! negative regulation of DNA replication GO:0008156 45 25 1,000 0,01580424 0,08774944 ! interaction with host GO:0051701 66 25 1,000 0,01580424 0,08755047 ! regulation of biomineral formation GO:0070167 56 25 1,000 0,01580424 0,08735239 ! leukocyte homeostasis GO:0001776 50 25 1,000 0,01580424 0,0871552 ! lung development GO:0030324 165 69 2,000 0,01633454 0,08987675 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 1,000 0,01703517 0,09352116 ! regulation of transcription factor import into nucleus GO:0042990 58 26 1,000 0,01703517 0,09331147 ! microtubule organizing center organization GO:0031023 42 26 1,000 0,01703517 0,09310272 GO:0051297|centrosome organization, ! regulation of cellular ketone metabolic process GO:0010565 51 26 1,000 0,01703517 0,0928949 ! negative regulation of cell development GO:0010721 83 26 1,000 0,01703517 0,09268801 GO:0050768|negative regulation of neurogenesis, ! positive regulation of nuclear division GO:0051785 41 26 1,000 0,01703517 0,09248204 GO:0045840|positive regulation of mitosis, ! neural tube closure GO:0001843 58 26 1,000 0,01703517 0,09227698 GO:0060606|tube closure, ! appendage morphogenesis GO:0035107 150 72 2,000 0,0182844 0,09882476 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 171 72 2,000 0,0182844 0,09860661 ! negative regulation of actin filament depolymerization GO:0030835 63 27 1,000 0,01830553 0,09850311 ! negative regulation of actin filament polymerization GO:0030837 61 27 1,000 0,01830553 0,09828662 ! tube lumen formation GO:0035148 59 27 1,000 0,01830553 0,09807108 ! regulation of endothelial cell proliferation GO:0001936 60 27 1,000 0,01830553 0,09785648 ! mitochondrial membrane organization GO:0007006 60 27 1,000 0,01830553 0,09764282 ! response to starvation GO:0042594 47 27 1,000 0,01830553 0,09743009 ! response to toxin GO:0009636 49 27 1,000 0,01830553 0,09721829 ! regulation of chromosome organization GO:0033044 49 27 1,000 0,01830553 0,0970074 ! cellular response to nutrient levels GO:0031669 45 27 1,000 0,01830553 0,09679743 ! appendage development GO:0048736 151 73 2,000 0,01896183 0,10005128 GO:0060173|limb development, ! protein amino acid acylation GO:0043543 59 28 1,000 0,01961465 0,10327283 ! dendrite development GO:0016358 67 28 1,000 0,01961465 0,10305074 ! base-excision repair GO:0006284 41 28 1,000 0,01961465 0,1028296 ! negative regulation of protein polymerization GO:0032272 63 28 1,000 0,01961465 0,10260941 ! respiratory system development GO:0060541 175 74 2,000 0,01965301 0,1025904 ! regulation of transcription factor activity GO:0051090 137 75 2,000 0,02035797 0,10604375 GO:0090046|regulation of transcription regulator activity, ! phosphoinositide-mediated signaling GO:0048015 141 75 2,000 0,02035797 0,10581812 ! eye development GO:0001654 155 75 2,000 0,02035797 0,10559346 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 1,000 0,02096186 0,10849539 ! primary neural tube formation GO:0014020 61 29 1,000 0,02096186 0,10826601 ! somitogenesis GO:0001756 52 29 1,000 0,02096186 0,1080376 ! cell-matrix adhesion GO:0007160 181 76 2,000 0,02107671 0,10840083 ! learning or memory GO:0007611 161 76 2,000 0,02107671 0,1081731 ! lymphocyte differentiation GO:0030098 193 76 2,000 0,02107671 0,10794632 ! regulation of catabolic process GO:0009894 173 77 2,000 0,02180923 0,11146432 ! regulation of actin filament depolymerization GO:0030834 67 30 1,000 0,0223465 0,1139718 ! negative regulation of protein complex assembly GO:0031333 68 30 1,000 0,0223465 0,11373436 ! acute-phase response GO:0006953 50 30 1,000 0,0223465 0,1134979 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 1,000 0,0223465 0,11326243 ! negative regulation of transcription regulator activity GO:0090048 57 30 1,000 0,0223465 0,11302793 GO:0043433|negative regulation of transcription factor activity, ! blood coagulation GO:0007596 151 79 2,000 0,02331564 0,11768616 GO:0050817|coagulation, ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 2,000 0,02331564 0,11744351 ! zinc ion transport GO:0006829 54 31 1,000 0,02376791 0,11947531 ! male gonad development GO:0008584 56 31 1,000 0,02376791 0,11922998 ! development of primary sexual characteristics GO:0045137 143 80 2,000 0,02408952 0,12059568 ! response to hypoxia GO:0001666 178 81 2,000 0,02487718 0,12428414 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 1,000 0,02522545 0,1257669 ! metanephros development GO:0001656 81 32 1,000 0,02522545 0,12551075 ! regulation of protein import into nucleus GO:0042306 69 32 1,000 0,02522545 0,12525565 ! mesoderm formation GO:0001707 73 32 1,000 0,02522545 0,12500158 ! cell-substrate adhesion GO:0031589 189 82 2,000 0,02567861 0,12698954 ! protein import into nucleus GO:0006606 174 82 2,000 0,02567861 0,126733 ! exocytosis GO:0006887 153 83 2,000 0,02649379 0,13049261 ! response to drug GO:0042493 149 83 2,000 0,02649379 0,13023005 ! response to oxygen levels GO:0070482 183 83 2,000 0,02649379 0,12996854 ! nuclear import GO:0051170 177 83 2,000 0,02649379 0,12970809 ! regulation of pH GO:0006885 56 33 1,000 0,02671849 0,13054654 ! positive regulation of gene-specific transcription GO:0043193 70 33 1,000 0,02671849 0,13028597 ! response to ionizing radiation GO:0010212 74 33 1,000 0,02671849 0,13002643 ! regulation of axonogenesis GO:0050770 86 33 1,000 0,02671849 0,12976793 ! T cell activation GO:0042110 189 84 2,000 0,02732272 0,13243931 ! response to nutrient GO:0007584 135 84 2,000 0,02732272 0,13217705 ! regulation of ligase activity GO:0051340 147 84 2,000 0,02732272 0,13191584 ! glial cell differentiation GO:0010001 67 34 1,000 0,02824639 0,13610637 ! post-embryonic development GO:0009791 76 34 1,000 0,02824639 0,13583845 ! formation of primary germ layer GO:0001704 76 34 1,000 0,02824639 0,13557157 ! cell fate specification GO:0001708 56 34 1,000 0,02824639 0,13530575 ! DNA damage checkpoint GO:0000077 78 35 1,000 0,02980853 0,14250929 ! negative regulation of DNA metabolic process GO:0051053 65 35 1,000 0,02980853 0,14223095 ! mesoderm morphogenesis GO:0048332 80 35 1,000 0,02980853 0,14195369 ! telencephalon development GO:0021537 81 35 1,000 0,02980853 0,14167752 ! calcium-mediated signaling GO:0019722 67 35 1,000 0,02980853 0,14140242 ! mitochondrion organization GO:0007005 159 87 2,000 0,02989181 0,14152265 ! regulation of protein transport GO:0051223 165 87 2,000 0,02989181 0,14124891 GO:0070201|regulation of establishment of protein localization, ! amine biosynthetic process GO:0009309 146 88 2,000 0,03077553 0,14514406 ! mitotic sister chromatid segregation GO:0000070 63 36 1,000 0,0314043 0,14782411 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 1,000 0,0314043 0,14753983 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 1,000 0,0314043 0,14725664 ! negative regulation of DNA binding GO:0043392 67 36 1,000 0,0314043 0,14697454 ! regulation of proteolysis GO:0030162 77 36 1,000 0,0314043 0,14669352 ! negative regulation of hydrolase activity GO:0051346 66 36 1,000 0,0314043 0,14641357 ! regulation of DNA binding GO:0051101 167 89 2,000 0,0316729 0,14738454 ! protein localization in nucleus GO:0034504 192 89 2,000 0,0316729 0,14710434 ! sister chromatid segregation GO:0000819 65 37 1,000 0,03303309 0,15313064 ! ossification GO:0001503 205 91 2,000 0,03350843 0,15503995 ! bone development GO:0060348 206 92 2,000 0,03444654 0,15907919 ! meiosis I GO:0007127 74 38 1,000 0,0346943 0,1599211 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 1,000 0,0346943 0,15961993 ! DNA integrity checkpoint GO:0031570 82 38 1,000 0,0346943 0,15931989 ! neural tube formation GO:0001841 79 38 1,000 0,0346943 0,15902098 ! regulation of membrane potential GO:0042391 179 94 2,000 0,03636327 0,16635855 ! regulation of neuron projection development GO:0010975 102 39 1,000 0,03638734 0,16615752 ! negative regulation of binding GO:0051100 71 39 1,000 0,03638734 0,16584753 ! mitotic cell cycle checkpoint GO:0007093 76 39 1,000 0,03638734 0,16553868 ! carbohydrate homeostasis GO:0033500 59 39 1,000 0,03638734 0,16523099 GO:0042593|glucose homeostasis, ! nucleotide catabolic process GO:0009166 70 39 1,000 0,03638734 0,16492444 ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 0,03638734 0,16461903 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 1,000 0,03638734 0,16431474 ! regulation of defense response GO:0031347 171 95 2,000 0,03734182 0,16831376 ! negative regulation of multicellular organismal process GO:0051241 174 95 2,000 0,03734182 0,16800379 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,03795619 0,17045401 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,03795619 0,17014125 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,03795619 0,16982964 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,03795619 0,16951916 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,03795619 0,16920982 ! neuron fate determination GO:0048664 7 5 0,000 0,03795619 0,16890161 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,03795619 0,16859451 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,03795619 0,16828853 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,03795619 0,16798366 ! polyol transport GO:0015791 12 5 0,000 0,03795619 0,16767989 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,03795619 0,16737722 ! response to superoxide GO:0000303 10 5 0,000 0,03795619 0,16707564 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,03795619 0,16677515 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,03795619 0,16647573 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,03795619 0,16617739 ! female meiosis GO:0007143 10 5 0,000 0,03795619 0,16588011 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,03795619 0,1655839 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,03795619 0,16528874 ! cobalt ion transport GO:0006824 11 5 0,000 0,03795619 0,16499463 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,03795619 0,16470157 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,03795619 0,16440954 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,03795619 0,16411855 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,03795619 0,16382859 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,03795619 0,16353965 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,03795619 0,16325173 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,03795619 0,16296482 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,03795619 0,16267891 ! transposition GO:0032196 9 5 0,000 0,03795619 0,16239401 ! negative chemotaxis GO:0050919 16 5 0,000 0,03795619 0,16211011 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,03795619 0,16182719 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,03795619 0,16154526 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,03795619 0,16126432 ! behavioral response to pain GO:0048266 10 5 0,000 0,03795619 0,16098434 ! clathrin coat assembly GO:0048268 15 5 0,000 0,03795619 0,16070534 ! Notch receptor processing GO:0007220 11 5 0,000 0,03795619 0,1604273 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,03795619 0,16015023 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,03795619 0,15987411 ! micturition GO:0060073 9 5 0,000 0,03795619 0,15959894 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,03795619 0,15932471 ! copulation GO:0007620 9 5 0,000 0,03795619 0,15905143 ! glial cell fate commitment GO:0021781 14 5 0,000 0,03795619 0,15877908 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,03795619 0,15850766 ! bioluminescence GO:0008218 9 5 0,000 0,03795619 0,15823717 ! spermidine metabolic process GO:0008216 7 5 0,000 0,03795619 0,1579676 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,03795619 0,15769895 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,03795619 0,15743121 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,03795619 0,15716438 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,03795619 0,15689845 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,03795619 0,15663341 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,03795619 0,15636928 ! grooming behavior GO:0007625 6 5 0,000 0,03795619 0,15610603 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,03795619 0,15584367 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,03795619 0,15558218 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,03795619 0,15532158 ! response to protozoan GO:0001562 13 5 0,000 0,03795619 0,15506184 ! lymph vessel development GO:0001945 10 5 0,000 0,03795619 0,15480297 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,03795619 0,15454497 ! endochondral ossification GO:0001958 17 5 0,000 0,03795619 0,15428782 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,03795619 0,15403153 ! single strand break repair GO:0000012 8 5 0,000 0,03795619 0,15377609 ! parathyroid gland development GO:0060017 14 5 0,000 0,03795619 0,15352149 ! anagen GO:0042640 7 5 0,000 0,03795619 0,15326774 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,03795619 0,15301482 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,03795619 0,15276274 ! cytokine secretion GO:0050663 15 5 0,000 0,03795619 0,15251148 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,03795619 0,15226105 ! ceramide catabolic process GO:0046514 7 5 0,000 0,03795619 0,15201144 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,03795619 0,15176265 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,03795619 0,15151468 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,03795619 0,15126751 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,03795619 0,15102114 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,03795619 0,15077558 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,03795619 0,15053081 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 0,03795619 0,15028684 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,03795619 0,15004366 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,03795619 0,14980126 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,03795619 0,14955965 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,03795619 0,14931881 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,03795619 0,14907875 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,03795619 0,14883946 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,03795619 0,14860093 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,03795619 0,14836317 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,03795619 0,14812617 ! polyol catabolic process GO:0046174 9 5 0,000 0,03795619 0,14788992 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,03795619 0,14765443 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,03795619 0,14741968 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,03795619 0,14718568 ! muscle cell migration GO:0014812 8 5 0,000 0,03795619 0,14695243 ! mitochondrial fission GO:0000266 8 5 0,000 0,03795619 0,14671991 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,03795619 0,14648812 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,03795619 0,14625707 ! mRNA transcription GO:0009299 10 5 0,000 0,03795619 0,14602674 ! nerve growth factor processing GO:0032455 9 5 0,000 0,03795619 0,14579714 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,03795619 0,14556826 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,03795619 0,1453401 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,03795619 0,14511265 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,03795619 0,14488591 ! monocyte activation GO:0042117 10 5 0,000 0,03795619 0,14465988 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,03795619 0,14443455 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,03795619 0,14420992 ! response to food GO:0032094 6 5 0,000 0,03795619 0,143986 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,03795619 0,14376276 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,03795619 0,14354022 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,03795619 0,14331836 ! forebrain neuron development GO:0021884 13 5 0,000 0,03795619 0,14309719 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,03795619 0,1428767 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,03795619 0,14265689 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,03795619 0,14243776 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,03795619 0,1422193 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,03795619 0,1420015 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,03795619 0,14178438 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,03795619 0,14156791 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,03795619 0,14135211 ! lipid glycosylation GO:0030259 7 5 0,000 0,03795619 0,14113696 ! nucleobase transport GO:0015851 6 5 0,000 0,03795619 0,14092246 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,03795619 0,14070862 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,03795619 0,14049543 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,03795619 0,14028288 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,03795619 0,14007097 ! basic amino acid transport GO:0015802 12 5 0,000 0,03795619 0,1398597 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,03795619 0,13964907 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,03795619 0,13943907 ! actin nucleation GO:0045010 11 5 0,000 0,03795619 0,1392297 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,03795619 0,13902096 ! depurination GO:0045007 5 5 0,000 0,03795619 0,13881285 ! depyrimidination GO:0045008 10 5 0,000 0,03795619 0,13860535 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,03795619 0,13839848 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,03795619 0,13819222 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,03795619 0,13798658 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,03795619 0,13778155 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,03795619 0,13757712 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,03795619 0,13737331 ! activated T cell proliferation GO:0050798 16 5 0,000 0,03795619 0,13717009 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,03795619 0,13696748 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,03795619 0,13676546 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,03795619 0,13656404 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,03795619 0,13636321 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,03795619 0,13616297 ! response to arsenic GO:0046685 11 5 0,000 0,03795619 0,13596332 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,03795619 0,13576425 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,03795619 0,13556576 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,03795619 0,13536786 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,03795619 0,13517053 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,03795619 0,13497377 ! response to mercury ion GO:0046689 8 5 0,000 0,03795619 0,13477759 ! response to cadmium ion GO:0046686 7 5 0,000 0,03795619 0,13458198 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,03795619 0,13438693 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,03795619 0,13419245 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,03795619 0,13399853 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,03795619 0,13380517 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,03795619 0,13361237 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,03795619 0,13342012 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,03795619 0,13322842 ! decidualization GO:0046697 11 5 0,000 0,03795619 0,13303728 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,03795619 0,13284668 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,03795619 0,13265663 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,03795619 0,13246712 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,03795619 0,13227815 ! embryonic cleavage GO:0040016 6 5 0,000 0,03795619 0,13208972 ! peroxisome fission GO:0016559 5 5 0,000 0,03795619 0,13190182 ! histone demethylation GO:0016577 13 5 0,000 0,03795619 0,13171446 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,03795619 0,13152763 ! mitotic recombination GO:0006312 9 5 0,000 0,03795619 0,13134133 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,03795619 0,13115556 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,03795619 0,13097031 ! metaphase plate congression GO:0051310 7 5 0,000 0,03795619 0,13078559 ! regulation of sterol transport GO:0032371 7 5 0,000 0,03795619 0,13060138 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,03795619 0,1304177 ! enteric nervous system development GO:0048484 8 5 0,000 0,03795619 0,13023452 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,03795619 0,13005187 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,03795619 0,12986972 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,03795619 0,12968809 ! muscle cell proliferation GO:0033002 12 5 0,000 0,03795619 0,12950696 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,03795619 0,12932633 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,03795619 0,12914621 ! B cell homeostasis GO:0001782 13 5 0,000 0,03795619 0,12896659 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,03795619 0,12878747 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,03795619 0,12860885 ! metaphase GO:0051323 11 5 0,000 0,03795619 0,12843072 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,03795619 0,12825309 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,03795619 0,12807594 ! cellular response to nutrient GO:0031670 8 5 0,000 0,03795619 0,12789928 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,03795619 0,12772311 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,03795619 0,12754743 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,03795619 0,12737223 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,03795619 0,12719751 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,03795619 0,12702326 ! response to redox state GO:0051775 6 5 0,000 0,03795619 0,1268495 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,03795619 0,1266762 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,03795619 0,12650339 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,03795619 0,12633104 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,03795619 0,12615916 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,03795619 0,12598775 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,03795619 0,1258168 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,03795619 0,12564632 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,03795619 0,12547629 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,03795619 0,12530673 ! striatum development GO:0021756 14 5 0,000 0,03795619 0,12513763 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,03795619 0,12496898 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,03795619 0,12480078 ! glial cell migration GO:0008347 10 5 0,000 0,03795619 0,12463304 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,03795619 0,12446575 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,03795619 0,1242989 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,03795619 0,12413251 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,03795619 0,12396655 ! T cell activation during immune response GO:0002286 9 5 0,000 0,03795619 0,12380104 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,03795619 0,12363598 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,03795619 0,12347135 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,03795619 0,12330716 ! neuroprotection GO:0043526 8 5 0,000 0,03795619 0,1231434 ! regulation of sensory perception GO:0051931 8 5 0,000 0,03795619 0,12298008 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,03795619 0,12281719 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,03795619 0,12265474 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,03795619 0,12249271 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,03795619 0,12233111 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,03795619 0,12216994 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,03795619 0,12200919 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,03795619 0,12184886 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,03795619 0,12168895 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,03795619 0,12152946 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,03795619 0,12137039 ! spindle assembly GO:0051225 6 5 0,000 0,03795619 0,12121174 ! receptor biosynthetic process GO:0032800 7 5 0,000 0,03795619 0,1210535 ! protein palmitoylation GO:0018345 12 5 0,000 0,03795619 0,12089567 ! drug metabolic process GO:0017144 7 5 0,000 0,03795619 0,12073826 ! organ regeneration GO:0031100 7 5 0,000 0,03795619 0,12058125 ! carnitine metabolic process GO:0009437 8 5 0,000 0,03795619 0,12042465 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,03795619 0,12026846 ! mammary gland development GO:0030879 93 40 1,000 0,03811162 0,12060452 ! nucleus organization GO:0006997 73 40 1,000 0,03811162 0,1204485 ! regulation of T cell activation GO:0050863 175 96 2,000 0,03833377 0,12099405 ! regulation of protein localization GO:0032880 188 97 2,000 0,03933908 0,12400692 ! cellular amide metabolic process GO:0043603 73 41 1,000 0,03986656 0,12550776 ! gliogenesis GO:0042063 91 41 1,000 0,03986656 0,12534623 ! multicellular organismal metabolic process GO:0044236 64 41 1,000 0,03986656 0,12518511 ! monovalent inorganic cation homeostasis GO:0055067 72 41 1,000 0,03986656 0,12502441 ! embryonic epithelial tube formation GO:0001838 85 41 1,000 0,03986656 0,12486413 ! leukocyte differentiation GO:0002521 232 98 2,000 0,0403577 0,12624055 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 1,000 0,0416516 0,13012131 ! cytokinesis GO:0000910 84 42 1,000 0,0416516 0,12995512 ! skeletal muscle tissue development GO:0007519 223 100 2,000 0,04243473 0,13222964 GO:0060538|skeletal muscle organ development, ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 0,04346616 0,13527114 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 1,000 0,04346616 0,13509903 ! glucose transport GO:0015758 66 43 1,000 0,04346616 0,13492737 ! development of primary male sexual characteristics GO:0046546 80 43 1,000 0,04346616 0,13475614 ! segmentation GO:0035282 78 43 1,000 0,04346616 0,13458535 ! hexose transport GO:0008645 68 44 1,000 0,0453097 0,14011594 GO:0015749|monosaccharide transport, ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,0453734 0,14013554 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,0453734 0,1399586 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,0453734 0,13978211 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,0453734 0,13960606 GO:0030816|positive regulation of cAMP metabolic process, ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,0453734 0,13943045 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,0453734 0,13925529 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,0453734 0,13908056 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,0453734 0,13890628 ! response to oxygen radical GO:0000305 11 6 0,000 0,0453734 0,13873243 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,0453734 0,13855901 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,0453734 0,13838603 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,0453734 0,13821348 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,0453734 0,13804136 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,0453734 0,13786966 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,0453734 0,1376984 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,0453734 0,13752756 ! forebrain regionalization GO:0021871 9 6 0,000 0,0453734 0,13735714 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,0453734 0,13718714 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,0453734 0,13701757 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,0453734 0,13684841 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,0453734 0,13667967 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,0453734 0,13651134 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,0453734 0,13634343 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,0453734 0,13617593 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,0453734 0,13600885 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,0453734 0,13584217 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,0453734 0,1356759 ! malate metabolic process GO:0006108 13 6 0,000 0,0453734 0,13551004 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,0453734 0,13534458 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,0453734 0,13517952 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,0453734 0,13501487 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,0453734 0,13485062 ! protein refolding GO:0042026 15 6 0,000 0,0453734 0,13468677 ! opsonization GO:0008228 8 6 0,000 0,0453734 0,13452331 ! mating behavior GO:0007617 7 6 0,000 0,0453734 0,13436025 ! erythrocyte maturation GO:0043249 8 6 0,000 0,0453734 0,13419759 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,0453734 0,13403532 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,0453734 0,13387344 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,0453734 0,13371195 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,0453734 0,13355086 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,0453734 0,13339014 ! response to interferon-gamma GO:0034341 16 6 0,000 0,0453734 0,13322982 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,0453734 0,13306988 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,0453734 0,13291032 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,0453734 0,13275115 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,0453734 0,13259236 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,0453734 0,13243394 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,0453734 0,13227591 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,0453734 0,13211825 ! thymic T cell selection GO:0045061 16 6 0,000 0,0453734 0,13196096 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,0453734 0,13180405 ! protein lipoylation GO:0009249 10 6 0,000 0,0453734 0,13164752 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,0453734 0,13149135 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,0453734 0,13133556 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,0453734 0,13118013 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,0453734 0,13102507 ! glutamate catabolic process GO:0006538 12 6 0,000 0,0453734 0,13087038 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,0453734 0,13071605 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,0453734 0,13056208 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,0453734 0,13040848 ! hyperosmotic response GO:0006972 10 6 0,000 0,0453734 0,13025524 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,0453734 0,13010236 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,0453734 0,12994984 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,0453734 0,12979767 ! urea metabolic process GO:0019627 7 6 0,000 0,0453734 0,12964586 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,0453734 0,1294944 ! neutrophil activation GO:0042119 7 6 0,000 0,0453734 0,1293433 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,0453734 0,12919255 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,0453734 0,12904215 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,0453734 0,1288921 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,0453734 0,1287424 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,0453734 0,12859305 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,0453734 0,12844404 ! neuron apoptosis GO:0051402 15 6 0,000 0,0453734 0,12829538 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,0453734 0,12814706 ! T cell mediated immunity GO:0002456 17 6 0,000 0,0453734 0,12799909 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,0453734 0,12785145 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,0453734 0,12770416 ! carnitine transport GO:0015879 10 6 0,000 0,0453734 0,1275572 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,0453734 0,12741059 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,0453734 0,12726431 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,0453734 0,12711836 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,0453734 0,12697275 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,0453734 0,12682747 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,0453734 0,12668253 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,0453734 0,12653791 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,0453734 0,12639363 ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,0453734 0,12624967 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,0453734 0,12610604 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,0453734 0,12596274 ! response to UV-C GO:0010225 14 6 0,000 0,0453734 0,12581976 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,0453734 0,12567711 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,0453734 0,12553478 ! interaction with symbiont GO:0051702 14 6 0,000 0,0453734 0,12539277 ! regulation of dendrite development GO:0050773 16 6 0,000 0,0453734 0,12525108 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,0453734 0,12510972 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,0453734 0,12496867 ! response to copper ion GO:0046688 10 6 0,000 0,0453734 0,12482794 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,0453734 0,12468753 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,0453734 0,12454743 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,0453734 0,12440764 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,0453734 0,12426817 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,0453734 0,12412901 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,0453734 0,12399017 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,0453734 0,12385163 ! hair follicle maturation GO:0048820 8 6 0,000 0,0453734 0,1237134 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,0453734 0,12357549 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,0453734 0,12343787 ! response to pheromone GO:0019236 6 6 0,000 0,0453734 0,12330057 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,0453734 0,12316357 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,0453734 0,12302687 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,0453734 0,12289048 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,0453734 0,12275439 ! subpallium development GO:0021544 15 6 0,000 0,0453734 0,1226186 ! neural tube patterning GO:0021532 8 6 0,000 0,0453734 0,12248311 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,0453734 0,12234791 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,0453734 0,12221302 ! maintenance of organ identity GO:0048496 9 6 0,000 0,0453734 0,12207843 ! G2 phase GO:0051319 16 6 0,000 0,0453734 0,12194413 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,0453734 0,12181012 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,0453734 0,12167641 ! oxygen homeostasis GO:0032364 10 6 0,000 0,0453734 0,12154299 ! establishment of planar polarity GO:0001736 7 6 0,000 0,0453734 0,12140987 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,0453734 0,12127704 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,0453734 0,12114449 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,0453734 0,12101224 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,0453734 0,12088027 ! receptor internalization GO:0031623 11 6 0,000 0,0453734 0,12074859 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,0453734 0,1206172 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,0453734 0,1204861 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,0453734 0,12035528 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,0453734 0,12022474 ! protein deubiquitination GO:0016579 16 6 0,000 0,0453734 0,12009449 ! protein destabilization GO:0031648 9 6 0,000 0,0453734 0,11996451 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,0453734 0,11983482 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,0453734 0,11970541 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,0453734 0,11957628 ! regulation of viral transcription GO:0046782 11 6 0,000 0,0453734 0,11944742 ! progesterone metabolic process GO:0042448 12 6 0,000 0,0453734 0,11931885 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,0453734 0,11919055 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,0453734 0,11906252 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,0453734 0,11893477 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,0453734 0,1188073 ! determination of adult lifespan GO:0008340 17 6 0,000 0,0453734 0,1186801 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,0453734 0,11855317 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,0453734 0,11842651 ! neural plate development GO:0001840 9 6 0,000 0,0453734 0,11830012 ! catecholamine transport GO:0051937 9 6 0,000 0,0453734 0,118174 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,0453734 0,11804815 ! sensory cilium assembly GO:0035058 10 6 0,000 0,0453734 0,11792256 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,0453734 0,11779725 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,0453734 0,1176722 ! maternal placenta development GO:0001893 12 6 0,000 0,0453734 0,11754741 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,0453734 0,11742289 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,0453734 0,11729864 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,0453734 0,11717464 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,0453734 0,11705091 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,0453734 0,11692744 ! keratinocyte differentiation GO:0030216 81 45 1,000 0,04718165 0,1214592 ! B cell differentiation GO:0030183 124 45 1,000 0,04718165 0,12133134 ! regulation of actin filament polymerization GO:0030833 99 46 1,000 0,04908148 0,12608418 ! pigmentation GO:0043473 103 46 1,000 0,04908148 0,12595174 ! cell growth GO:0016049 90 46 1,000 0,04908148 0,12581958 ! neural tube development GO:0021915 91 47 1,000 0,05100865 0,13062277 ! tRNA transcription GO:0009304 17 7 0,000 0,05273362 0,13489868 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,05273362 0,13475757 GO:0045346|regulation of MHC class II biosynthetic process, ! behavioral response to cocaine GO:0048148 14 7 0,000 0,05273362 0,13461676 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,05273362 0,13447624 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,05273362 0,13433602 ! sleep GO:0030431 16 7 0,000 0,05273362 0,13419608 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,05273362 0,13405644 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,05273362 0,13391709 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,05273362 0,13377803 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,05273362 0,13363925 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,05273362 0,13350077 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,05273362 0,13336257 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,05273362 0,13322465 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,05273362 0,13308703 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,05273362 0,13294968 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,05273362 0,13281262 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,05273362 0,13267584 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,05273362 0,13253934 ! glycolipid transport GO:0046836 11 7 0,000 0,05273362 0,13240313 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,05273362 0,13226719 GO:0051923|sulfation, ! neuron adhesion GO:0007158 14 7 0,000 0,05273362 0,13213153 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,05273362 0,13199615 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,05273362 0,13186104 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,05273362 0,13172622 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,05273362 0,13159167 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,05273362 0,13145739 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,05273362 0,13132339 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,05273362 0,13118965 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,05273362 0,1310562 ! lipoprotein transport GO:0042953 14 7 0,000 0,05273362 0,13092301 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,05273362 0,13079009 ! rhythmic behavior GO:0007622 17 7 0,000 0,05273362 0,13065744 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,05273362 0,13052507 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,05273362 0,13039296 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,05273362 0,13026111 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,05273362 0,13012954 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,05273362 0,12999822 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,05273362 0,12986718 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,05273362 0,1297364 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,05273362 0,12960588 ! mechanosensory behavior GO:0007638 16 7 0,000 0,05273362 0,12947562 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,05273362 0,12934562 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,05273362 0,12921589 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,05273362 0,12908641 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,05273362 0,1289572 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,05273362 0,12882824 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,05273362 0,12869954 ! spinal cord patterning GO:0021511 14 7 0,000 0,05273362 0,1285711 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,05273362 0,12844291 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,05273362 0,12831498 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,05273362 0,1281873 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,05273362 0,12805988 ! adrenal gland development GO:0030325 17 7 0,000 0,05273362 0,12793271 ! cysteine metabolic process GO:0006534 13 7 0,000 0,05273362 0,12780579 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,05273362 0,12767913 ! ovulation GO:0030728 10 7 0,000 0,05273362 0,12755271 ! adenohypophysis development GO:0021984 11 7 0,000 0,05273362 0,12742655 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,05273362 0,12730063 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,05273362 0,12717497 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,05273362 0,12704955 ! microtubule nucleation GO:0007020 21 7 0,000 0,05273362 0,12692438 ! proline biosynthetic process GO:0006561 10 7 0,000 0,05273362 0,12679945 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,05273362 0,12667477 ! thyroid hormone generation GO:0006590 13 7 0,000 0,05273362 0,12655033 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,05273362 0,12642614 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,05273362 0,1263022 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,05273362 0,12617849 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,05273362 0,12605503 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,05273362 0,12593181 ! galactose metabolic process GO:0006012 13 7 0,000 0,05273362 0,12580883 ! vesicle fusion GO:0006906 20 7 0,000 0,05273362 0,12568609 ! response to dietary excess GO:0002021 8 7 0,000 0,05273362 0,12556359 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,05273362 0,12544132 ! intracellular pH reduction GO:0051452 13 7 0,000 0,05273362 0,1253193 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,05273362 0,12519751 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,05273362 0,12507596 ! organ growth GO:0035265 15 7 0,000 0,05273362 0,12495465 ! nucleoside transport GO:0015858 11 7 0,000 0,05273362 0,12483357 ! nucleoside salvage GO:0043174 11 7 0,000 0,05273362 0,12471272 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,05273362 0,12459211 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,05273362 0,12447173 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,05273362 0,12435158 ! parturition GO:0007567 16 7 0,000 0,05273362 0,12423167 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,05273362 0,12411199 ! rRNA modification GO:0000154 14 7 0,000 0,05273362 0,12399253 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,05273362 0,12387331 ! spindle checkpoint GO:0031577 16 7 0,000 0,05273362 0,12375431 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,05273362 0,12363555 ! monocyte differentiation GO:0030224 16 7 0,000 0,05273362 0,12351701 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,05273362 0,1233987 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,05273362 0,12328061 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,05273362 0,12316275 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,05273362 0,12304512 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,05273362 0,12292771 ! fibrinolysis GO:0042730 11 7 0,000 0,05273362 0,12281052 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,05273362 0,12269356 ! eating behavior GO:0042755 8 7 0,000 0,05273362 0,12257682 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,05273362 0,1224603 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,05273362 0,12234401 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,05273362 0,12222793 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,05273362 0,12211208 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,05273362 0,12199644 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,05273362 0,12188102 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,05273362 0,12176582 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,05273362 0,12165084 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,05273362 0,12153608 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,05273362 0,12142153 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,05273362 0,12130719 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,05273362 0,12119308 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,05273362 0,12107917 ! histone ubiquitination GO:0016574 9 7 0,000 0,05273362 0,12096548 ! regulation of meiosis GO:0040020 12 7 0,000 0,05273362 0,12085201 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,05273362 0,12073874 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,05273362 0,12062569 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,05273362 0,12051285 ! membrane to membrane docking GO:0022614 14 7 0,000 0,05273362 0,12040022 ! transcription termination GO:0006353 14 7 0,000 0,05273362 0,12028781 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,05273362 0,1201756 ! anaphase GO:0051322 18 7 0,000 0,05273362 0,1200636 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,05273362 0,11995181 ! axonal fasciculation GO:0007413 19 7 0,000 0,05273362 0,11984022 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,05273362 0,11972885 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,05273362 0,11961768 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,05273362 0,11950672 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,05273362 0,11939596 ! diuresis GO:0030146 12 7 0,000 0,05273362 0,11928541 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,05273362 0,11917506 ! thiamin metabolic process GO:0006772 7 7 0,000 0,05273362 0,11906492 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,05273362 0,11895498 ! antibiotic transport GO:0042891 9 7 0,000 0,05273362 0,11884524 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,05273362 0,11873571 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,05273362 0,11862637 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,05273362 0,11851724 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,05273362 0,11840831 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,05273362 0,11829958 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,05273362 0,11819105 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,05273362 0,11808271 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,05273362 0,11797458 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,05273362 0,11786664 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,05273362 0,1177589 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,05273362 0,11765136 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,05273362 0,11754402 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,05273362 0,11743686 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,05273362 0,11732991 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,05273362 0,11722315 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,05273362 0,11711658 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,05273362 0,11701021 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,05273362 0,11690403 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,05273362 0,11679804 ! muscle adaptation GO:0043500 13 7 0,000 0,05273362 0,11669225 ! embryonic heart tube development GO:0035050 14 7 0,000 0,05273362 0,11658664 ! retina homeostasis GO:0001895 12 7 0,000 0,05273362 0,11648123 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,05273362 0,11637601 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,05273362 0,11627098 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,05273362 0,11616613 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,05273362 0,11606148 ! mitochondrial transport GO:0006839 94 48 1,000 0,05296262 0,11646056 ! regulation of JAK-STAT cascade GO:0046425 76 48 1,000 0,05296262 0,11635583 ! cellular component disassembly GO:0022411 89 48 1,000 0,05296262 0,11625129 ! positive regulation of DNA binding GO:0043388 83 48 1,000 0,05296262 0,11614693 ! vascular process in circulatory system GO:0003018 85 48 1,000 0,05296262 0,11604276 ! JAK-STAT cascade GO:0007259 82 48 1,000 0,05296262 0,11593878 ! JNK cascade GO:0007254 106 49 1,000 0,05494288 0,12016602 ! protein homooligomerization GO:0051260 84 49 1,000 0,05494288 0,12005854 ! endocrine system development GO:0035270 109 50 1,000 0,05694889 0,12433079 ! regulation of ossification GO:0030278 123 50 1,000 0,05694889 0,12421978 ! epidermal cell differentiation GO:0009913 87 50 1,000 0,05694889 0,12410897 ! regulation of cell projection organization GO:0031344 135 51 1,000 0,05898017 0,12842117 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 1,000 0,05898017 0,12830681 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,06003731 0,13049034 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,06003731 0,13037435 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,06003731 0,13025856 GO:0016446|somatic hypermutation of immunoglobulin genes, ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,06003731 0,13014298 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,06003731 0,13002761 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,06003731 0,12991243 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,06003731 0,12979747 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,06003731 0,1296827 ! meiotic prophase I GO:0007128 14 8 0,000 0,06003731 0,12956814 ! response to zinc ion GO:0010043 12 8 0,000 0,06003731 0,12945379 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 0,06003731 0,12933963 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,06003731 0,12922567 ! oligopeptide transport GO:0006857 16 8 0,000 0,06003731 0,12911192 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,06003731 0,12899836 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,06003731 0,12888501 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,06003731 0,12877185 ! signal peptide processing GO:0006465 12 8 0,000 0,06003731 0,12865889 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,06003731 0,12854613 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,06003731 0,12843357 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,06003731 0,12832121 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,06003731 0,12820904 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,06003731 0,12809706 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,06003731 0,12798529 ! estrogen metabolic process GO:0008210 17 8 0,000 0,06003731 0,1278737 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,06003731 0,12776232 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,06003731 0,12765112 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,06003731 0,12754012 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,06003731 0,12742931 ! reflex GO:0060004 17 8 0,000 0,06003731 0,1273187 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,06003731 0,12720827 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,06003731 0,12709804 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,06003731 0,126988 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,06003731 0,12687815 ! pigment granule organization GO:0048753 17 8 0,000 0,06003731 0,12676849 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,06003731 0,12665901 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,06003731 0,12654973 ! histidine catabolic process GO:0006548 10 8 0,000 0,06003731 0,12644064 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,06003731 0,12633173 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,06003731 0,12622301 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,06003731 0,12611448 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,06003731 0,12600613 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,06003731 0,12589797 ! melanin metabolic process GO:0006582 17 8 0,000 0,06003731 0,12579 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,06003731 0,12568221 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,06003731 0,1255746 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,06003731 0,12546718 ! macrophage activation GO:0042116 13 8 0,000 0,06003731 0,12535995 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,06003731 0,12525289 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,06003731 0,12514602 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,06003731 0,12503933 ! purine salvage GO:0043101 12 8 0,000 0,06003731 0,12493283 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,06003731 0,1248265 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,06003731 0,12472036 ! osteoblast development GO:0002076 17 8 0,000 0,06003731 0,12461439 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,06003731 0,12450861 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,06003731 0,124403 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,06003731 0,12429758 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,06003731 0,12419233 ! response to UV-B GO:0010224 17 8 0,000 0,06003731 0,12408726 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,06003731 0,12398237 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,06003731 0,12387765 ! intermediate filament organization GO:0045109 12 8 0,000 0,06003731 0,12377311 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,06003731 0,12366875 ! cellular extravasation GO:0045123 13 8 0,000 0,06003731 0,12356456 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,06003731 0,12346055 ! response to antibiotic GO:0046677 11 8 0,000 0,06003731 0,12335672 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,06003731 0,12325306 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,06003731 0,12314957 ! DNA topological change GO:0006265 12 8 0,000 0,06003731 0,12304626 ! response to tropane GO:0014073 15 8 0,000 0,06003731 0,12294312 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,06003731 0,12284015 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,06003731 0,12273735 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,06003731 0,12263473 ! mast cell activation GO:0045576 14 8 0,000 0,06003731 0,12253228 ! multicellular organismal aging GO:0010259 20 8 0,000 0,06003731 0,12243 ! gas homeostasis GO:0033483 14 8 0,000 0,06003731 0,12232789 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,06003731 0,12222595 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,06003731 0,12212418 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,06003731 0,12202258 ! nucleosome disassembly GO:0006337 14 8 0,000 0,06003731 0,12192115 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,06003731 0,12181988 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,06003731 0,12171879 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,06003731 0,12161786 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,06003731 0,1215171 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,06003731 0,12141651 ! intracellular lipid transport GO:0032365 16 8 0,000 0,06003731 0,12131608 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,06003731 0,12121582 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,06003731 0,12111572 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,06003731 0,12101579 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,06003731 0,12091603 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,06003731 0,12081642 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,06003731 0,12071699 ! hormone catabolic process GO:0042447 17 8 0,000 0,06003731 0,12061771 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,06003731 0,1205186 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,06003731 0,12041965 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,06003731 0,12032087 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,06003731 0,12022224 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,06003731 0,12012378 GO:0010828|positive regulation of glucose transport, ! adult feeding behavior GO:0008343 10 8 0,000 0,06003731 0,12002548 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,06003731 0,11992734 ! ATP catabolic process GO:0006200 11 8 0,000 0,06003731 0,11982936 ! blastocyst growth GO:0001832 19 8 0,000 0,06003731 0,11973154 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,06003731 0,11963388 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,06003731 0,11953638 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,06003731 0,11943904 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,06003731 0,11934185 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,06003731 0,11924483 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,06003731 0,11914796 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,06003731 0,11905125 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,06003731 0,11895469 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,06003731 0,1188583 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,06003731 0,11876206 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,06003731 0,11866597 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,06003731 0,11857004 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,06003731 0,11847426 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,06003731 0,11837864 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,06003731 0,11828318 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,06003731 0,11818786 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,06003731 0,1180927 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,06003731 0,1179977 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,06003731 0,11790284 ! positive regulation of binding GO:0051099 88 52 1,000 0,06103619 0,1197682 ! response to estrogen stimulus GO:0043627 98 52 1,000 0,06103619 0,11967207 ! Notch signaling pathway GO:0007219 111 52 1,000 0,06103619 0,11957611 ! morphogenesis of embryonic epithelium GO:0016331 106 52 1,000 0,06103619 0,11948029 ! histone modification GO:0016570 104 52 1,000 0,06103619 0,11938463 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 1,000 0,06103619 0,11928912 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 1,000 0,06311646 0,1232562 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 1,000 0,06311646 0,12315775 ! regulation of neuron apoptosis GO:0043523 117 53 1,000 0,06311646 0,12305946 ! synapse organization GO:0050808 102 53 1,000 0,06311646 0,12296132 ! regulation of translational initiation GO:0006446 87 54 1,000 0,06522048 0,12695907 ! activation of phospholipase C activity GO:0007202 110 54 1,000 0,06522048 0,12685799 GO:0010863|positive regulation of phospholipase C activity, ! membrane fusion GO:0006944 122 54 1,000 0,06522048 0,12675707 ! covalent chromatin modification GO:0016569 115 54 1,000 0,06522048 0,1266563 ! epithelial tube morphogenesis GO:0060562 114 54 1,000 0,06522048 0,1265557 ! axon extension GO:0048675 16 9 0,000 0,06728488 0,13045791 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,06728488 0,13035445 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,06728488 0,13025116 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,06728488 0,13014803 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,06728488 0,13004506 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,06728488 0,12994226 ! reproductive behavior GO:0019098 22 9 0,000 0,06728488 0,12983962 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,06728488 0,12973714 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,06728488 0,12963483 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,06728488 0,12953267 ! UTP metabolic process GO:0046051 10 9 0,000 0,06728488 0,12943068 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,06728488 0,12932884 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,06728488 0,12922717 ! artery development GO:0060840 25 9 0,000 0,06728488 0,12912566 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,06728488 0,1290243 ! equilibrioception GO:0050957 20 9 0,000 0,06728488 0,12892311 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,06728488 0,12882207 ! chemosensory behavior GO:0007635 21 9 0,000 0,06728488 0,12872119 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,06728488 0,12862047 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,06728488 0,12851991 ! leukocyte degranulation GO:0043299 16 9 0,000 0,06728488 0,1284195 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,06728488 0,12831925 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,06728488 0,12821916 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,06728488 0,12811922 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,06728488 0,12801944 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,06728488 0,12791981 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,06728488 0,12782034 ! protein targeting to ER GO:0045047 25 9 0,000 0,06728488 0,12772103 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,06728488 0,12762186 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,06728488 0,12752286 ! T cell selection GO:0045058 27 9 0,000 0,06728488 0,127424 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,06728488 0,1273253 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,06728488 0,12722675 ! endosome organization GO:0007032 20 9 0,000 0,06728488 0,12712835 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,06728488 0,12703011 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,06728488 0,12693202 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,06728488 0,12683407 ! mannose metabolic process GO:0006013 13 9 0,000 0,06728488 0,12673628 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,06728488 0,12663864 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,06728488 0,12654116 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,06728488 0,12644382 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,06728488 0,12634663 ! receptor clustering GO:0043113 20 9 0,000 0,06728488 0,12624959 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,06728488 0,12615269 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,06728488 0,12605595 ! retinol metabolic process GO:0042572 20 9 0,000 0,06728488 0,12595936 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,06728488 0,12586291 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,06728488 0,12576661 GO:0007351|tripartite regional subdivision, ! macrophage differentiation GO:0030225 15 9 0,000 0,06728488 0,12567046 ! oligodendrocyte development GO:0014003 11 9 0,000 0,06728488 0,12557445 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,06728488 0,1254786 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,06728488 0,12538288 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,06728488 0,12528732 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,06728488 0,1251919 ! response to amine stimulus GO:0014075 13 9 0,000 0,06728488 0,12509662 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,06728488 0,12500149 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,06728488 0,12490651 ! erythrocyte development GO:0048821 17 9 0,000 0,06728488 0,12481166 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,06728488 0,12471697 ! renal water homeostasis GO:0003091 15 9 0,000 0,06728488 0,12462241 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,06728488 0,124528 ! icosanoid secretion GO:0032309 15 9 0,000 0,06728488 0,12443373 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,06728488 0,12433961 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,06728488 0,12424562 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,06728488 0,12415178 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,06728488 0,12405808 ! sterol catabolic process GO:0016127 14 9 0,000 0,06728488 0,12396453 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,06728488 0,12387111 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,06728488 0,12377783 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,06728488 0,1236847 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,06728488 0,1235917 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,06728488 0,12349884 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,06728488 0,12340613 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,06728488 0,12331355 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,06728488 0,12322111 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,06728488 0,12312881 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,06728488 0,12303665 ! purine base metabolic process GO:0006144 25 9 0,000 0,06728488 0,12294462 ! pigment granule transport GO:0051904 17 9 0,000 0,06728488 0,12285274 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,06728488 0,12276099 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,06728488 0,12266937 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,06728488 0,1225779 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,06728488 0,12248656 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,06728488 0,12239535 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,06728488 0,12230429 ! mitochondrion localization GO:0051646 18 9 0,000 0,06728488 0,12221335 ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 0,06734777 0,12223671 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 1,000 0,06734777 0,12214596 ! regulation of protein polymerization GO:0032271 117 55 1,000 0,06734777 0,12205535 ! skeletal muscle fiber development GO:0048741 130 56 1,000 0,06949785 0,1258586 ! regulation of protein catabolic process GO:0042176 126 56 1,000 0,06949785 0,12576537 ! RNA elongation GO:0006354 90 56 1,000 0,06949785 0,12567228 ! muscle fiber development GO:0048747 131 57 1,000 0,07167025 0,12950474 ! regulation of phospholipase activity GO:0010517 113 57 1,000 0,07167025 0,12940903 ! heart morphogenesis GO:0003007 105 57 1,000 0,07167025 0,12931345 ! regulation of actin filament length GO:0030832 118 58 1,000 0,07386449 0,13317412 ! gastrulation GO:0007369 122 58 1,000 0,07386449 0,13307591 ! positive regulation of organelle organization GO:0010638 108 58 1,000 0,07386449 0,13297785 ! positive regulation of lipase activity GO:0060193 115 58 1,000 0,07386449 0,13287993 ! maintenance of location GO:0051235 124 58 1,000 0,07386449 0,13278215 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,07447677 0,13378438 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,07447677 0,13368608 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,07447677 0,13358793 ! associative learning GO:0008306 21 10 0,000 0,07447677 0,13348992 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,07447677 0,13339205 ! phosphate transport GO:0006817 24 10 0,000 0,07447677 0,13329433 ! cell volume homeostasis GO:0006884 17 10 0,000 0,07447677 0,13319675 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,07447677 0,13309931 ! CTP metabolic process GO:0046036 11 10 0,000 0,07447677 0,13300202 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! GTP metabolic process GO:0046039 11 10 0,000 0,07447677 0,13290486 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,07447677 0,13280785 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,07447677 0,13271098 ! social behavior GO:0035176 29 10 0,000 0,07447677 0,13261425 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,07447677 0,13251767 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,07447677 0,13242122 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,07447677 0,13232491 ! androgen metabolic process GO:0008209 17 10 0,000 0,07447677 0,13222875 ! phospholipid efflux GO:0033700 19 10 0,000 0,07447677 0,13213272 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,07447677 0,13203683 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,07447677 0,13194109 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,07447677 0,13184548 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,07447677 0,13175001 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,07447677 0,13165467 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,07447677 0,13155948 ! endoderm development GO:0007492 18 10 0,000 0,07447677 0,13146442 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,07447677 0,1313695 ! arginine catabolic process GO:0006527 17 10 0,000 0,07447677 0,13127472 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,07447677 0,13118007 ! proline metabolic process GO:0006560 13 10 0,000 0,07447677 0,13108556 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,07447677 0,13099119 GO:0005978|glycogen biosynthetic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,07447677 0,13089695 ! V(D)J recombination GO:0033151 34 10 0,000 0,07447677 0,13080284 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,07447677 0,13070888 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,07447677 0,13061504 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,07447677 0,13052135 ! B cell proliferation GO:0042100 19 10 0,000 0,07447677 0,13042778 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,07447677 0,13033435 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,07447677 0,13024106 ! multicellular organism growth GO:0035264 19 10 0,000 0,07447677 0,1301479 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,07447677 0,13005487 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,07447677 0,12996197 ! ruffle organization GO:0031529 17 10 0,000 0,07447677 0,12986921 ! epithelial cell development GO:0002064 21 10 0,000 0,07447677 0,12977657 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,07447677 0,12968408 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,07447677 0,12959171 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,07447677 0,12949947 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,07447677 0,12940737 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,07447677 0,12931539 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,07447677 0,12922355 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 13 10 0,000 0,07447677 0,12913184 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,07447677 0,12904025 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,07447677 0,1289488 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,07447677 0,12885748 ! segment specification GO:0007379 15 10 0,000 0,07447677 0,12876628 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,07447677 0,12867522 ! blastoderm segmentation GO:0007350 19 10 0,000 0,07447677 0,12858428 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,07447677 0,12849347 ! response to dsRNA GO:0043331 23 10 0,000 0,07447677 0,12840279 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,07447677 0,12831224 ! melanosome localization GO:0032400 16 10 0,000 0,07447677 0,12822182 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,07447677 0,12813152 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,07447677 0,12804135 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,07447677 0,12795131 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,07447677 0,12786139 ! induction of an organ GO:0001759 17 10 0,000 0,07447677 0,1277716 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,07447677 0,12768194 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,07447677 0,1275924 ! protein sumoylation GO:0016925 17 10 0,000 0,07447677 0,12750298 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,07447677 0,1274137 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,07447677 0,12732453 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,07447677 0,12723549 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,07447677 0,12714658 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,07447677 0,12705779 ! salivary gland development GO:0007431 28 10 0,000 0,07447677 0,12696913 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,07447677 0,12688058 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,07447677 0,12679217 ! midbrain development GO:0030901 14 10 0,000 0,07447677 0,12670387 ! musculoskeletal movement GO:0050881 16 10 0,000 0,07447677 0,1266157 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,07447677 0,12652765 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,07447677 0,12643972 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,07447677 0,12635191 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,07447677 0,12626423 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,07447677 0,12617667 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,07447677 0,12608923 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,07447677 0,12600191 ! detection of calcium ion GO:0005513 24 10 0,000 0,07447677 0,12591471 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,07447677 0,12582763 ! blastocyst formation GO:0001825 18 10 0,000 0,07447677 0,12574068 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,07447677 0,12565384 ! cerebellar cortex development GO:0021695 16 10 0,000 0,07447677 0,12556712 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,07447677 0,12548052 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,07447677 0,12539404 ! response to nicotine GO:0035094 20 10 0,000 0,07447677 0,12530768 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,07447677 0,12522144 ! establishment of organelle localization GO:0051656 122 59 1,000 0,07608011 0,12782923 ! DNA catabolic process GO:0006308 94 60 1,000 0,07831665 0,13149662 ! regulation of endocytosis GO:0030100 104 60 1,000 0,07831665 0,1314063 ! kidney development GO:0001822 133 60 1,000 0,07831665 0,13131611 ! regulation of cellular component size GO:0032535 125 61 1,000 0,08057367 0,13500787 ! cytokine-mediated signaling pathway GO:0019221 112 61 1,000 0,08057367 0,13491533 ! camera-type eye development GO:0043010 126 61 1,000 0,08057367 0,13482292 ! respiratory burst GO:0045730 17 11 0,000 0,08161341 0,13646925 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,08161341 0,1363759 ! neuron fate specification GO:0048665 18 11 0,000 0,08161341 0,13628269 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,08161341 0,1361896 ! thyroid gland development GO:0030878 26 11 0,000 0,08161341 0,13609663 ! synapsis GO:0007129 14 11 0,000 0,08161341 0,1360038 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,08161341 0,13591109 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,08161341 0,13581851 ! response to pain GO:0048265 27 11 0,000 0,08161341 0,13572605 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,08161341 0,13563372 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,08161341 0,13554152 ! bone resorption GO:0045453 16 11 0,000 0,08161341 0,13544944 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,08161341 0,13535748 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,08161341 0,13526565 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,08161341 0,13517394 ! melanocyte differentiation GO:0030318 20 11 0,000 0,08161341 0,13508236 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,08161341 0,13499091 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,08161341 0,13489957 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,08161341 0,13480836 GO:0010833|telomere maintenance via telomere lengthening, ! substrate-bound cell migration GO:0006929 14 11 0,000 0,08161341 0,13471728 ! UV protection GO:0009650 20 11 0,000 0,08161341 0,13462631 ! adult heart development GO:0007512 16 11 0,000 0,08161341 0,13453547 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,08161341 0,13444475 ! macroautophagy GO:0016236 19 11 0,000 0,08161341 0,13435416 ! temperature homeostasis GO:0001659 18 11 0,000 0,08161341 0,13426368 ! behavioral fear response GO:0001662 27 11 0,000 0,08161341 0,13417333 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,08161341 0,1340831 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,08161341 0,13399299 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,08161341 0,133903 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,08161341 0,13381313 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,08161341 0,13372339 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,08161341 0,13363376 ! regulation of organ growth GO:0046620 14 11 0,000 0,08161341 0,13354425 ! pigment granule localization GO:0051875 20 11 0,000 0,08161341 0,13345487 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,08161341 0,1333656 ! vasoconstriction GO:0042310 20 11 0,000 0,08161341 0,13327645 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,08161341 0,13318742 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,08161341 0,13309851 ! embryonic axis specification GO:0000578 19 11 0,000 0,08161341 0,13300972 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,08161341 0,13292105 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,08161341 0,13283249 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,08161341 0,13274405 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,08161341 0,13265573 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,08161341 0,13256753 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,08161341 0,13247945 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,08161341 0,13239148 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,08161341 0,13230363 ! prophase GO:0051324 17 11 0,000 0,08161341 0,13221589 ! neuroblast proliferation GO:0007405 25 11 0,000 0,08161341 0,13212828 ! nucleosome positioning GO:0016584 15 11 0,000 0,08161341 0,13204077 ! regulation of isotype switching GO:0045191 24 11 0,000 0,08161341 0,13195339 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,08161341 0,13186612 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,08161341 0,13177896 ! apical protein localization GO:0045176 18 11 0,000 0,08161341 0,13169192 ! acid secretion GO:0046717 20 11 0,000 0,08161341 0,131605 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,08161341 0,13151819 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,08161341 0,13143149 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,08161341 0,13134491 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,08161341 0,13125844 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,08161341 0,13117208 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,08161341 0,13108584 ! cholesterol efflux GO:0033344 21 11 0,000 0,08161341 0,13099972 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,08161341 0,1309137 ! oocyte development GO:0048599 20 11 0,000 0,08161341 0,1308278 ! germ cell migration GO:0008354 26 11 0,000 0,08161341 0,13074201 ! embryonic gut development GO:0048566 19 11 0,000 0,08161341 0,13065634 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,08161341 0,13057077 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,08161341 0,13048532 ! activation of innate immune response GO:0002218 16 11 0,000 0,08161341 0,13039998 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,08161341 0,13031475 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,08161341 0,13022963 ! lysogeny GO:0030069 22 11 0,000 0,08161341 0,13014463 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,08161341 0,13005973 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,08161341 0,12997495 ! sequestering of metal ion GO:0051238 15 11 0,000 0,08161341 0,12989027 ! nucleus localization GO:0051647 22 11 0,000 0,08161341 0,12980571 ! viral reproductive process GO:0022415 132 62 1,000 0,08285071 0,13168789 ! regulation of homeostatic process GO:0032844 148 62 1,000 0,08285071 0,13160227 ! regulation of protein complex assembly GO:0043254 132 63 1,000 0,08514734 0,13516242 ! integrin-mediated signaling pathway GO:0007229 160 64 1,000 0,08746313 0,13874832 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,08869522 0,14061157 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,08869522 0,14052038 ! mating GO:0007618 17 12 0,000 0,08869522 0,14042931 ! protein complex disassembly GO:0043241 28 12 0,000 0,08869522 0,14033836 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,08869522 0,14024753 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,08869522 0,14015681 ! hippocampus development GO:0021766 29 12 0,000 0,08869522 0,14006621 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,08869522 0,13997573 ! T cell proliferation GO:0042098 32 12 0,000 0,08869522 0,13988536 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,08869522 0,13979512 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,08869522 0,13970498 ! ventral spinal cord development GO:0021517 25 12 0,000 0,08869522 0,13961497 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,08869522 0,13952507 ! drug transport GO:0015893 16 12 0,000 0,08869522 0,13943528 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,08869522 0,13934561 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,08869522 0,13925606 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,08869522 0,13916662 ! polyamine metabolic process GO:0006595 18 12 0,000 0,08869522 0,1390773 ! mitotic spindle organization GO:0007052 23 12 0,000 0,08869522 0,13898809 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,08869522 0,13889899 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,08869522 0,13881001 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 21 12 0,000 0,08869522 0,13872115 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,08869522 0,13863239 ! entry into host cell GO:0030260 34 12 0,000 0,08869522 0,13854375 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,08869522 0,13845523 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,08869522 0,13836681 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,08869522 0,13827851 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,08869522 0,13819032 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,08869522 0,13810225 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,08869522 0,13801429 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,08869522 0,13792643 ! snRNA metabolic process GO:0016073 30 12 0,000 0,08869522 0,1378387 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,08869522 0,13775107 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,08869522 0,13766355 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,08869522 0,13757615 ! cranial nerve development GO:0021545 23 12 0,000 0,08869522 0,13748885 ! fucose catabolic process GO:0019317 25 12 0,000 0,08869522 0,13740167 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,08869522 0,13731459 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,08869522 0,13722763 ! autonomic nervous system development GO:0048483 24 12 0,000 0,08869522 0,13714078 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,08869522 0,13705403 ! zymogen activation GO:0031638 18 12 0,000 0,08869522 0,1369674 ! T cell homeostasis GO:0043029 28 12 0,000 0,08869522 0,13688088 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,08869522 0,13679446 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,08869522 0,13670816 ! oocyte differentiation GO:0009994 21 12 0,000 0,08869522 0,13662196 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,08869522 0,13653587 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,08869522 0,13644989 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,08869522 0,13636402 ! defense response to fungus GO:0050832 15 12 0,000 0,08869522 0,13627826 ! developmental induction GO:0031128 22 12 0,000 0,08869522 0,1361926 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,08869522 0,13610705 ! lamellipodium assembly GO:0030032 24 12 0,000 0,08869522 0,13602161 ! response to cold GO:0009409 17 12 0,000 0,08869522 0,13593628 ! establishment of cell polarity GO:0030010 21 12 0,000 0,08869522 0,13585105 ! regulation of cytokine biosynthetic process GO:0042035 108 66 1,000 0,09215044 0,14105484 ! regulation of lipid metabolic process GO:0019216 132 66 1,000 0,09215044 0,14096652 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 1,000 0,09452113 0,14450258 ! secondary metabolic process GO:0019748 125 67 1,000 0,09452113 0,14441221 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,09572262 0,14615648 ! cGMP metabolic process GO:0046068 18 13 0,000 0,09572262 0,14606519 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,09572262 0,14597401 ! regulation of chemokine production GO:0032642 18 13 0,000 0,09572262 0,14588295 ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,09572262 0,145792 ! peroxisomal transport GO:0043574 28 13 0,000 0,09572262 0,14570116 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,09572262 0,14561044 ! cartilage condensation GO:0001502 22 13 0,000 0,09572262 0,14551983 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,09572262 0,14542933 ! organelle fusion GO:0048284 36 13 0,000 0,09572262 0,14533894 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,09572262 0,14524867 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,09572262 0,14515851 ! endocrine pancreas development GO:0031018 25 13 0,000 0,09572262 0,14506846 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,09572262 0,14497853 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,09572262 0,1448887 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,09572262 0,14479899 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,09572262 0,14470938 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,09572262 0,14461989 ! methionine metabolic process GO:0006555 31 13 0,000 0,09572262 0,14453051 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,09572262 0,14444124 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,09572262 0,14435208 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,09572262 0,14426302 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,09572262 0,14417408 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! cytokine metabolic process GO:0042107 24 13 0,000 0,09572262 0,14408525 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,09572262 0,14399653 ! exocrine system development GO:0035272 34 13 0,000 0,09572262 0,14390792 ! asymmetric protein localization GO:0008105 24 13 0,000 0,09572262 0,14381941 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,09572262 0,14373102 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,09572262 0,14364273 ! L-glutamate transport GO:0015813 30 13 0,000 0,09572262 0,14355455 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,09572262 0,14346648 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,09572262 0,14337852 ! protein homotetramerization GO:0051289 24 13 0,000 0,09572262 0,14329066 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,09572262 0,14320292 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,09572262 0,14311528 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,09572262 0,14302774 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,09572262 0,14294032 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,09572262 0,142853 ! histone methylation GO:0016571 29 13 0,000 0,09572262 0,14276579 ! chromatin silencing GO:0006342 29 13 0,000 0,09572262 0,14267868 ! gland morphogenesis GO:0022612 31 13 0,000 0,09572262 0,14259168 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,09572262 0,14250479 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,09572262 0,142418 ! regulation of epidermis development GO:0045682 19 13 0,000 0,09572262 0,14233132 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,09572262 0,14224475 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,09572262 0,14215827 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,09572262 0,14207191 ! spleen development GO:0048536 24 13 0,000 0,09572262 0,14198565 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,09572262 0,14189949 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,09572262 0,14181344 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,09572262 0,14172749 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,09572262 0,14164165 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,09572262 0,14155591 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,09572262 0,14147027 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,09572262 0,14138474 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,09572262 0,14129931 ! insulin secretion GO:0030073 24 13 0,000 0,09572262 0,14121399 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,09572262 0,14112876 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,09572262 0,14104364 ! acrosome reaction GO:0007340 19 13 0,000 0,09572262 0,14095863 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,09572262 0,14087371 ! regulation of cellular response to stress GO:0080135 142 68 1,000 0,09690928 0,14253424 ! viral reproduction GO:0016032 142 68 1,000 0,09690928 0,14244848 ! regulation of lipase activity GO:0060191 137 68 1,000 0,09690928 0,14236283 ! adaptive immune response GO:0002250 126 68 1,000 0,09690928 0,14227727 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 1,000 0,09690928 0,14219182 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 1,000 0,0993145 0,14563345 ! homeostasis of number of cells GO:0048872 131 69 1,000 0,0993145 0,14554609 ! cellular amino acid catabolic process GO:0009063 120 69 1,000 0,0993145 0,14545883 ! germ cell development GO:0007281 133 70 1,000 0,10173637 0,14891669 ! rRNA transcription GO:0009303 28 14 0,000 0,10269602 0,15023137 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,10269602 0,15014146 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,10269602 0,15005167 ! water transport GO:0006833 21 14 0,000 0,10269602 0,14996198 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,10269602 0,14987239 ! non-recombinational repair GO:0000726 29 14 0,000 0,10269602 0,14978292 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,10269602 0,14969355 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,10269602 0,14960429 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,10269602 0,14951513 ! RNA polyadenylation GO:0043631 32 14 0,000 0,10269602 0,14942608 ! palate development GO:0060021 32 14 0,000 0,10269602 0,14933714 ! regulated secretory pathway GO:0045055 24 14 0,000 0,10269602 0,1492483 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,10269602 0,14915956 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,10269602 0,14907094 ! arginine metabolic process GO:0006525 21 14 0,000 0,10269602 0,14898242 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,10269602 0,148894 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,10269602 0,14880569 ! regulation of heart rate GO:0002027 25 14 0,000 0,10269602 0,14871748 ! fear response GO:0042596 34 14 0,000 0,10269602 0,14862938 ! organic alcohol transport GO:0015850 29 14 0,000 0,10269602 0,14854138 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,10269602 0,14845348 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,10269602 0,14836569 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,10269602 0,14827801 ! neutral amino acid transport GO:0015804 28 14 0,000 0,10269602 0,14819042 ! bone mineralization GO:0030282 18 14 0,000 0,10269602 0,14810294 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,10269602 0,14801557 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,10269602 0,14792829 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,10269602 0,14784112 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,10269602 0,14775406 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,10269602 0,14766709 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,10269602 0,14758023 ! ribosome assembly GO:0042255 18 14 0,000 0,10269602 0,14749347 ! cerebellum development GO:0021549 23 14 0,000 0,10269602 0,14740681 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,10269602 0,14732025 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,10269602 0,1472338 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,10269602 0,14714744 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,10269602 0,14706119 ! NADP metabolic process GO:0006739 24 14 0,000 0,10269602 0,14697504 ! oxygen transport GO:0015671 22 14 0,000 0,10269602 0,14688899 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,10269602 0,14680304 ! male genitalia development GO:0030539 26 14 0,000 0,10269602 0,14671719 ! regulation of axon extension GO:0030516 43 14 0,000 0,10269602 0,14663144 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,10269602 0,14654579 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,10269602 0,14646024 ! carbohydrate transport GO:0008643 114 72 1,000 0,10662851 0,15197985 ! actin filament organization GO:0007015 167 72 1,000 0,10662851 0,15189123 ! B cell activation GO:0042113 179 72 1,000 0,10662851 0,15180271 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 1,000 0,10662851 0,1517143 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 1,000 0,10662851 0,15162599 ! lactation GO:0007595 30 15 0,000 0,10961585 0,15578331 ! reproductive cellular process GO:0048610 22 15 0,000 0,10961585 0,15569274 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,10961585 0,15560227 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,10961585 0,15551191 ! superoxide anion generation GO:0042554 22 15 0,000 0,10961585 0,15542166 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,10961585 0,1553315 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,10961585 0,15524146 ! copper ion transport GO:0006825 22 15 0,000 0,10961585 0,15515151 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,10961585 0,15506168 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,10961585 0,15497194 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,10961585 0,15488231 ! sulfate transport GO:0008272 27 15 0,000 0,10961585 0,15479278 ! response to cAMP GO:0051591 25 15 0,000 0,10961585 0,15470336 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,10961585 0,15461404 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,10961585 0,15452482 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,10961585 0,15443571 ! response to hexose stimulus GO:0009746 25 15 0,000 0,10961585 0,15434669 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,10961585 0,15425778 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,10961585 0,15416898 ! vesicle coating GO:0006901 38 15 0,000 0,10961585 0,15408027 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,10961585 0,15399167 ! regulation of exocytosis GO:0017157 26 15 0,000 0,10961585 0,15390317 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,10961585 0,15381477 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,10961585 0,15372647 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,10961585 0,15363827 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,10961585 0,15355018 ! regulation of vasodilation GO:0042312 27 15 0,000 0,10961585 0,15346219 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,10961585 0,15337429 ! histone deacetylation GO:0016575 24 15 0,000 0,10961585 0,1532865 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,10961585 0,15319881 ! water homeostasis GO:0030104 28 15 0,000 0,10961585 0,15311121 ! cofactor transport GO:0051181 30 15 0,000 0,10961585 0,15302372 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,10961585 0,15293633 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,10961585 0,15284904 ! intestinal absorption GO:0050892 31 15 0,000 0,10961585 0,15276184 ! dopamine metabolic process GO:0042417 35 15 0,000 0,10961585 0,15267475 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,10961585 0,15258776 ! heme biosynthetic process GO:0006783 33 15 0,000 0,10961585 0,15250086 ! cell killing GO:0001906 32 15 0,000 0,10961585 0,15241407 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,10961585 0,15232737 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,10961585 0,15224077 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,10961585 0,15215427 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,10961585 0,15206787 ! actin filament polymerization GO:0030041 27 15 0,000 0,10961585 0,15198156 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,10961585 0,15189536 ! acute inflammatory response GO:0002526 118 74 1,000 0,11158258 0,15453302 ! amino acid transport GO:0006865 148 74 1,000 0,11158258 0,15444546 ! organelle localization GO:0051640 155 74 1,000 0,11158258 0,15435801 ! transition metal ion transport GO:0000041 143 75 1,000 0,11408188 0,15772611 ! positive regulation of cell size GO:0045793 29 16 0,000 0,1164825 0,16095404 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,1164825 0,16086305 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,1164825 0,16077217 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,1164825 0,16068139 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,1164825 0,16059071 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,1164825 0,16050014 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,1164825 0,16040966 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,1164825 0,16031929 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,1164825 0,16022902 ! startle response GO:0001964 28 16 0,000 0,1164825 0,16013885 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,1164825 0,16004879 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,1164825 0,15995882 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,1164825 0,15986896 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,1164825 0,15977919 ! protein polyubiquitination GO:0000209 41 16 0,000 0,1164825 0,15968953 ! glutamate metabolic process GO:0006536 25 16 0,000 0,1164825 0,15959997 ! response to osmotic stress GO:0006970 27 16 0,000 0,1164825 0,15951051 ! lysosomal transport GO:0007041 31 16 0,000 0,1164825 0,15942114 ! L-amino acid transport GO:0015807 33 16 0,000 0,1164825 0,15933188 ! stem cell development GO:0048864 46 16 0,000 0,1164825 0,15924272 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,1164825 0,15915366 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,1164825 0,1590647 ! intermediate filament-based process GO:0045103 36 16 0,000 0,1164825 0,15897583 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,1164825 0,15888707 ! negative regulation of immune response GO:0050777 38 16 0,000 0,1164825 0,15879841 ! axon cargo transport GO:0008088 46 16 0,000 0,1164825 0,15870984 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,1164825 0,15862137 ! neuron recognition GO:0008038 40 16 0,000 0,1164825 0,158533 ! mRNA splice site selection GO:0006376 44 16 0,000 0,1164825 0,15844473 ! tissue regeneration GO:0042246 27 16 0,000 0,1164825 0,15835656 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,1164825 0,15826849 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,1164825 0,15818051 ! biomineral formation GO:0031214 22 16 0,000 0,1164825 0,15809263 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,1164825 0,15800485 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,1164825 0,15791717 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,1164825 0,15782959 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,1164825 0,1577421 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,1164825 0,1576547 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,1164825 0,15756741 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,1164825 0,15748021 ! peptide hormone processing GO:0016486 27 16 0,000 0,1164825 0,15739311 ! regulation of actin cytoskeleton organization GO:0032956 167 76 1,000 0,11659554 0,15745876 ! amine catabolic process GO:0009310 136 77 1,000 0,11912317 0,16078338 ! regulation of vesicle-mediated transport GO:0060627 136 77 1,000 0,11912317 0,16069459 ! positive regulation of ligase activity GO:0051351 130 77 1,000 0,11912317 0,16060591 ! antigen processing and presentation GO:0019882 117 78 1,000 0,12166443 0,16394164 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 0,12166443 0,16385126 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,12329639 0,16595761 ! metencephalon development GO:0022037 32 17 0,000 0,12329639 0,16586623 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,12329639 0,16577494 ! signal complex assembly GO:0007172 47 17 0,000 0,12329639 0,16568376 ! gene silencing by RNA GO:0031047 38 17 0,000 0,12329639 0,16559267 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,12329639 0,16550169 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,12329639 0,1654108 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,12329639 0,16532002 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,12329639 0,16522933 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,12329639 0,16513874 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,12329639 0,16504826 ! myoblast differentiation GO:0045445 50 17 0,000 0,12329639 0,16495787 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,12329639 0,16486758 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,12329639 0,16477739 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,12329639 0,1646873 ! NAD metabolic process GO:0019674 33 17 0,000 0,12329639 0,16459731 ! membrane budding GO:0006900 42 17 0,000 0,12329639 0,16450741 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,12329639 0,16441761 ! regulation of protein binding GO:0043393 33 17 0,000 0,12329639 0,16432792 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,12329639 0,16423831 ! genitalia development GO:0048806 32 17 0,000 0,12329639 0,16414881 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,12329639 0,16405941 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,12329639 0,1639701 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,12329639 0,16388089 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,12329639 0,16379177 ! steroid catabolic process GO:0006706 34 17 0,000 0,12329639 0,16370276 ! gas transport GO:0015669 26 17 0,000 0,12329639 0,16361383 ! organic cation transport GO:0015695 32 17 0,000 0,12329639 0,16352501 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,12329639 0,16343628 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,12329639 0,16334765 ! regulation of actin filament-based process GO:0032970 170 79 1,000 0,12421894 0,16448069 ! response to steroid hormone stimulus GO:0048545 147 79 1,000 0,12421894 0,16439159 ! regulation of synaptic transmission GO:0050804 159 79 1,000 0,12421894 0,16430258 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 1,000 0,12678636 0,16760773 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 1,000 0,12936634 0,17092589 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,13005791 0,17174675 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,13005791 0,17165396 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,13005791 0,17156128 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,13005791 0,17146869 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,13005791 0,1713762 ! adult walking behavior GO:0007628 36 18 0,000 0,13005791 0,17128382 ! patterning of blood vessels GO:0001569 43 18 0,000 0,13005791 0,17119153 ! heart looping GO:0001947 34 18 0,000 0,13005791 0,17109934 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,13005791 0,17100726 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,13005791 0,17091527 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,13005791 0,17082338 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,13005791 0,17073159 ! glutamine metabolic process GO:0006541 29 18 0,000 0,13005791 0,17063989 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,13005791 0,1705483 ! DNA integration GO:0015074 32 18 0,000 0,13005791 0,1704568 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,13005791 0,17036541 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,13005791 0,17027411 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,13005791 0,1701829 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,13005791 0,1700918 ! neural crest cell migration GO:0001755 41 18 0,000 0,13005791 0,17000079 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,13005791 0,16990988 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,13005791 0,16981907 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,13005791 0,16972836 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,13005791 0,16963774 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,13005791 0,16954722 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,13005791 0,16945679 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,13005791 0,16936646 ! nerve development GO:0021675 34 18 0,000 0,13005791 0,16927623 ! defense response to virus GO:0051607 43 18 0,000 0,13005791 0,16918609 ! inorganic anion transport GO:0015698 156 83 1,000 0,1345626 0,17495287 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,13676748 0,17772498 ! positive regulation of translation GO:0045727 31 19 0,000 0,13676748 0,17763049 ! negative regulation of defense response GO:0031348 27 19 0,000 0,13676748 0,17753611 ! neuron maturation GO:0042551 46 19 0,000 0,13676748 0,17744183 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,13676748 0,17734764 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,13676748 0,17725356 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,13676748 0,17715957 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,13676748 0,17706569 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,13676748 0,17697191 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,13676748 0,17687822 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,13676748 0,17678463 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,13676748 0,17669115 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,13676748 0,17659776 ! heme metabolic process GO:0042168 40 19 0,000 0,13676748 0,17650447 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,13676748 0,17641128 ! response to fungus GO:0009620 26 19 0,000 0,13676748 0,17631818 ! protein export from nucleus GO:0006611 40 19 0,000 0,13676748 0,17622519 ! heart process GO:0003015 32 19 0,000 0,13676748 0,17613229 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,13676748 0,17603949 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,13676748 0,17594679 ! visual learning GO:0008542 38 19 0,000 0,13676748 0,17585419 ! cellular pigmentation GO:0033059 37 19 0,000 0,13676748 0,17576168 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,13676748 0,17566927 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,13676748 0,17557696 ! vitamin transport GO:0051180 31 19 0,000 0,13676748 0,17548475 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,13676748 0,17539263 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,13676748 0,17530061 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,13676748 0,17520868 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,13676748 0,17511685 ! cilium assembly GO:0042384 38 19 0,000 0,13676748 0,17502512 ! peptide hormone secretion GO:0030072 32 19 0,000 0,13676748 0,17493349 ! regulation of neuron differentiation GO:0045664 187 85 1,000 0,13980502 0,1787251 ! regulation of transmission of nerve impulse GO:0051969 167 85 1,000 0,13980502 0,17863163 ! positive regulation of cell activation GO:0050867 161 86 1,000 0,14244272 0,18190672 GO:0002696|positive regulation of leukocyte activation, ! protein secretion GO:0009306 45 20 0,000 0,14342549 0,18306608 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,14342549 0,18297048 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,14342549 0,18287498 ! positive regulation of ossification GO:0045778 50 20 0,000 0,14342549 0,18277959 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,14342549 0,18268429 ! skin development GO:0043588 42 20 0,000 0,14342549 0,18258909 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,14342549 0,18249399 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,14342549 0,18239899 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,14342549 0,18230409 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,14342549 0,18220929 ! bile acid metabolic process GO:0008206 34 20 0,000 0,14342549 0,18211459 ! response to alkaloid GO:0043279 38 20 0,000 0,14342549 0,18201998 ! retinoid metabolic process GO:0001523 34 20 0,000 0,14342549 0,18192548 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,14342549 0,18183107 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,14342549 0,18173676 ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,14342549 0,18164255 GO:0030968|endoplasmic reticulum unfolded protein response, ! body fluid secretion GO:0007589 33 20 0,000 0,14342549 0,18154843 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,14342549 0,18145441 ! peptide secretion GO:0002790 38 20 0,000 0,14342549 0,18136049 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,14342549 0,18126667 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,14342549 0,18117294 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,14342549 0,18107931 GO:0006626|protein targeting to mitochondrion, ! cell-cell junction organization GO:0045216 43 20 0,000 0,14342549 0,18098578 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,14342549 0,18089234 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,14342549 0,180799 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,14342549 0,18070576 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,14342549 0,18061261 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,14342549 0,18051956 ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,14342549 0,18042661 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,14342549 0,18033375 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,14342549 0,18024098 ! regulation of cell killing GO:0031341 46 21 0,000 0,15003233 0,18844678 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,15003233 0,18834994 ! hormone secretion GO:0046879 39 21 0,000 0,15003233 0,1882532 ! cAMP metabolic process GO:0046058 41 21 0,000 0,15003233 0,18815656 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,15003233 0,18806002 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,15003233 0,18796358 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,15003233 0,18786724 ! ovarian follicle development GO:0001541 39 21 0,000 0,15003233 0,18777099 ! smooth muscle contraction GO:0006939 48 21 0,000 0,15003233 0,18767485 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,15003233 0,1875788 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,15003233 0,18748286 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,15003233 0,187387 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,15003233 0,18729125 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,15003233 0,1871956 ! sensory perception of pain GO:0019233 33 21 0,000 0,15003233 0,18710004 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,15003233 0,18700458 ! collagen fibril organization GO:0030199 62 21 0,000 0,15003233 0,18690922 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,15003233 0,18681396 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,15003233 0,18671879 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,15003233 0,18662372 ! collagen catabolic process GO:0030574 29 21 0,000 0,15003233 0,18652874 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,15003233 0,18643387 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,15003233 0,18633909 ! sperm-egg recognition GO:0035036 23 21 0,000 0,15003233 0,1862444 ! actin filament-based movement GO:0030048 47 21 0,000 0,15003233 0,18614981 ! tube morphogenesis GO:0035239 194 89 1,000 0,1504179 0,18653347 ! regulation of neurological system process GO:0031644 175 89 1,000 0,1504179 0,18643883 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,1565884 0,19398857 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,1565884 0,19389024 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,1565884 0,19379202 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,1565884 0,1936939 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,1565884 0,19359588 ! microtubule-based transport GO:0010970 59 22 0,000 0,1565884 0,19349795 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,1565884 0,19340013 ! vacuolar transport GO:0007034 41 22 0,000 0,1565884 0,1933024 ! central nervous system neuron development GO:0021954 47 22 0,000 0,1565884 0,19320477 ! fucose metabolic process GO:0006004 44 22 0,000 0,1565884 0,19310724 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,1565884 0,19300981 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,1565884 0,19291248 ! ureteric bud development GO:0001657 50 22 0,000 0,1565884 0,19281525 ! stem cell differentiation GO:0048863 57 22 0,000 0,1565884 0,19271811 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,1565884 0,19262107 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,1565884 0,19252413 ! cytolysis GO:0019835 27 22 0,000 0,1565884 0,19242729 ! renal system process GO:0003014 42 22 0,000 0,1565884 0,19233054 ! vasodilation GO:0042311 40 22 0,000 0,1565884 0,1922339 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,1565884 0,19213734 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,1565884 0,19204089 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,1565884 0,19194453 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,1565884 0,19184827 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,1565884 0,19175211 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,1565884 0,19165604 ! sarcomere organization GO:0045214 32 22 0,000 0,1565884 0,19156007 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,1565884 0,19146419 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,1565884 0,19136841 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,1565884 0,19127273 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,1565884 0,19117714 ! gut development GO:0048565 44 22 0,000 0,1565884 0,19108164 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,1565884 0,19098625 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,1565884 0,19089094 ! protein stabilization GO:0050821 41 22 0,000 0,1565884 0,19079574 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 1,000 0,16118477 0,1962983 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 1,000 0,16118477 0,19620049 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,16309408 0,19842571 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,16309408 0,19832694 ! gluconeogenesis GO:0006094 38 23 0,000 0,16309408 0,19822827 ! glycerol metabolic process GO:0006071 40 23 0,000 0,16309408 0,1981297 ! viral genome replication GO:0019079 44 23 0,000 0,16309408 0,19803123 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,16309408 0,19793285 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,16309408 0,19783457 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,16309408 0,19773639 ! regeneration GO:0031099 42 23 0,000 0,16309408 0,19763831 ! axis specification GO:0009798 43 23 0,000 0,16309408 0,19754032 ! visual behavior GO:0007632 46 23 0,000 0,16309408 0,19744243 ! regulation of DNA recombination GO:0000018 51 23 0,000 0,16309408 0,19734464 ! response to ethanol GO:0045471 47 23 0,000 0,16309408 0,19724694 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,16309408 0,19714935 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,16309408 0,19705184 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,16309408 0,19695444 ! peroxisome organization GO:0007031 43 23 0,000 0,16309408 0,19685713 ! lysosome organization GO:0007040 47 23 0,000 0,16309408 0,19675992 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,16309408 0,1966628 ! vesicle targeting GO:0006903 49 23 0,000 0,16309408 0,19656578 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,16309408 0,19646885 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,16309408 0,19637202 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,16309408 0,19627529 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,16309408 0,19617865 ! DNA modification GO:0006304 36 23 0,000 0,16309408 0,1960821 ! fatty acid transport GO:0015908 47 23 0,000 0,16309408 0,19598565 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,16309408 0,1958893 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,16309408 0,19579304 ! hormone transport GO:0009914 41 23 0,000 0,16309408 0,19569687 ! cell-cell recognition GO:0009988 28 23 0,000 0,16309408 0,1956008 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,16309408 0,19550482 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,16309408 0,19540894 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,16309408 0,19531315 ! nitrogen compound catabolic process GO:0044270 167 94 1,000 0,16389828 0,19618006 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,16954976 0,20284528 GO:0016444|somatic cell DNA recombination, ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,16954976 0,20274599 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,16954976 0,2026468 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,16954976 0,2025477 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,16954976 0,20244871 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,16954976 0,20234981 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,16954976 0,202251 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,16954976 0,2021523 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,16954976 0,20205369 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,16954976 0,20195517 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,16954976 0,20185675 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,16954976 0,20175843 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,16954976 0,2016602 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,16954976 0,20156207 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,16954976 0,20146404 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,16954976 0,20136609 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,16954976 0,20126825 ! membrane depolarization GO:0051899 45 24 0,000 0,16954976 0,2011705 ! oogenesis GO:0048477 44 24 0,000 0,16954976 0,20107284 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,16954976 0,20097528 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,16954976 0,20087782 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,16954976 0,20078044 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,16954976 0,20068317 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,16954976 0,20058598 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,16954976 0,20048889 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,16954976 0,2003919 ! regulation of amine transport GO:0051952 41 24 0,000 0,16954976 0,200295 ! transcription initiation GO:0006352 171 97 1,000 0,17208648 0,20319346 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,17595582 0,20766187 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,17595582 0,2075616 ! phototransduction GO:0007602 37 25 0,000 0,17595582 0,20746142 ! keratinization GO:0031424 37 25 0,000 0,17595582 0,20736135 ! vacuole organization GO:0007033 49 25 0,000 0,17595582 0,20726136 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,17595582 0,20716148 ! receptor metabolic process GO:0043112 53 25 0,000 0,17595582 0,20706169 ! chromosome condensation GO:0030261 48 25 0,000 0,17595582 0,206962 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,17595582 0,2068624 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,17595582 0,2067629 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,17595582 0,20666349 ! immunoglobulin production GO:0002377 62 25 0,000 0,17595582 0,20656418 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,17595582 0,20646497 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,17595582 0,20636585 ! liver development GO:0001889 55 25 0,000 0,17595582 0,20626683 ! initiation of viral infection GO:0019059 60 26 0,000 0,18231265 0,21361621 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,18231265 0,2135138 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,18231265 0,2134115 ! molting cycle process GO:0022404 52 26 0,000 0,18231265 0,21330929 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,18231265 0,21320718 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,18231265 0,21310516 GO:0006479|protein amino acid methylation, ! spinal cord development GO:0021510 54 26 0,000 0,18231265 0,21300325 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,18231265 0,21290143 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,18231265 0,21279971 ! digestive system process GO:0022600 49 26 0,000 0,18231265 0,21269809 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,18231265 0,21259656 ! osteoblast differentiation GO:0001649 63 26 0,000 0,18231265 0,21249513 ! neural crest cell development GO:0014032 59 26 0,000 0,18231265 0,2123938 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,18231265 0,21229256 ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,18231265 0,21219142 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,18231265 0,21209038 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,18231265 0,21198943 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,18231265 0,21188858 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,18231265 0,21178782 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,18231265 0,21168716 ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,18231265 0,2115866 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,18231265 0,21148613 ! blastocyst development GO:0001824 50 26 0,000 0,18231265 0,21138576 ! telomere organization GO:0032200 46 26 0,000 0,18231265 0,21128548 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,18231265 0,2111853 ! alditol metabolic process GO:0019400 44 26 0,000 0,18231265 0,21108521 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,18231265 0,21098522 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,18231265 0,21088532 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,18862061 0,21807863 ! embryonic pattern specification GO:0009880 49 27 0,000 0,18862061 0,21797548 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,18862061 0,21787241 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,18862061 0,21776945 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,18862061 0,21766658 ! iron ion transport GO:0006826 65 27 0,000 0,18862061 0,21756381 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,18862061 0,21746114 ! superoxide metabolic process GO:0006801 41 27 0,000 0,18862061 0,21735856 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,18862061 0,21725608 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,18862061 0,2171537 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,18862061 0,21705142 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,18862061 0,21694923 ! leukocyte proliferation GO:0070661 59 27 0,000 0,18862061 0,21684713 GO:0032943|mononuclear cell proliferation, ! neuron fate commitment GO:0048663 52 28 0,000 0,19488009 0,22393794 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,19488009 0,22383266 ! vesicle docking GO:0048278 55 28 0,000 0,19488009 0,22372747 ! circadian rhythm GO:0007623 56 28 0,000 0,19488009 0,22362239 ! fat cell differentiation GO:0045444 57 28 0,000 0,19488009 0,2235174 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,19488009 0,22341251 ! sperm motility GO:0030317 37 28 0,000 0,19488009 0,22330772 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,19488009 0,22320303 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,19488009 0,22309844 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,19488009 0,22299394 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,19488009 0,22288954 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,19488009 0,22278524 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,19488009 0,22268104 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,19488009 0,22257694 ! glutathione metabolic process GO:0006749 42 28 0,000 0,19488009 0,22247293 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,19488009 0,22236902 ! lipid oxidation GO:0034440 48 28 0,000 0,19488009 0,2222652 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,19488009 0,22216149 ! translational initiation GO:0006413 66 29 0,000 0,20109146 0,22913546 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,20109146 0,22902864 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,20109146 0,22892192 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,20109146 0,22881529 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,20109146 0,22870877 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,20109146 0,22860234 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,20109146 0,22849601 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,20109146 0,22838979 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,20109146 0,22828366 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,20109146 0,22817763 ! synaptogenesis GO:0007416 46 29 0,000 0,20109146 0,22807169 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,20109146 0,22796586 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,20109146 0,22786013 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,20109146 0,22775449 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,20109146 0,22764895 ! phenol metabolic process GO:0018958 56 30 0,000 0,20725508 0,2345179 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,20725508 0,23440933 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,20725508 0,23430086 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,20725508 0,23419249 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,20725508 0,23408421 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,20725508 0,23397604 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,20725508 0,23386797 ! myofibril assembly GO:0030239 50 30 0,000 0,20725508 0,23376 GO:0055002|striated muscle cell development, ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,20725508 0,23365212 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,20725508 0,23354435 ! cell fate determination GO:0001709 64 30 0,000 0,20725508 0,23343668 ! phospholipid transport GO:0015914 65 30 0,000 0,20725508 0,2333291 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,20725508 0,23322163 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,20725508 0,23311425 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,20725508 0,23300697 ! tissue homeostasis GO:0001894 50 30 0,000 0,20725508 0,23289979 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 52 30 0,000 0,20725508 0,23279271 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,21337132 0,23955245 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,21337132 0,23944241 GO:0009799|determination of symmetry, ! amino sugar metabolic process GO:0006040 41 31 0,000 0,21337132 0,23933247 ! regulation of innate immune response GO:0045088 57 31 0,000 0,21337132 0,23922264 ! ovulation cycle process GO:0022602 55 31 0,000 0,21337132 0,2391129 ! peptide transport GO:0015833 60 31 0,000 0,21337132 0,23900327 ! iron ion homeostasis GO:0055072 60 31 0,000 0,21337132 0,23889373 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,21337132 0,2387843 ! detection of light stimulus GO:0009583 44 31 0,000 0,21337132 0,23867497 ! natural killer cell activation GO:0030101 50 31 0,000 0,21337132 0,23856573 ! cofactor catabolic process GO:0051187 54 31 0,000 0,21337132 0,2384566 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,21337132 0,23834756 ! eye morphogenesis GO:0048592 65 31 0,000 0,21337132 0,23823863 ! response to heat GO:0009408 54 31 0,000 0,21337132 0,2381298 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,21337132 0,23802106 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,21944054 0,2446797 ! collagen metabolic process GO:0032963 49 32 0,000 0,21944054 0,24456808 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,21944054 0,24445656 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,21944054 0,24434514 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,21944054 0,24423382 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,21944054 0,2441226 ! muscle cell development GO:0055001 52 32 0,000 0,21944054 0,24401148 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,21944054 0,24390047 ! ovulation cycle GO:0042698 57 32 0,000 0,21944054 0,24378956 ! BMP signaling pathway GO:0030509 71 32 0,000 0,21944054 0,24367874 ! hindbrain development GO:0030902 65 32 0,000 0,21944054 0,24356803 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,21944054 0,24345742 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,21944054 0,24334691 ! gene silencing GO:0016458 71 32 0,000 0,21944054 0,24323649 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,2254631 0,2497988 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,2254631 0,24968556 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,2254631 0,24957243 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,2254631 0,2494594 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,2254631 0,24934647 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,2254631 0,24923365 ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,2254631 0,24912092 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,2254631 0,2490083 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,2254631 0,24889578 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,2254631 0,24878336 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,23143937 0,25526247 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,23143937 0,25514728 ! cholesterol transport GO:0030301 62 34 0,000 0,23143937 0,25503219 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,23143937 0,25491721 ! spliceosome assembly GO:0000245 75 34 0,000 0,23143937 0,25480233 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,23143937 0,25468755 ! adult locomotory behavior GO:0008344 62 34 0,000 0,23143937 0,25457288 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,23736968 0,26097846 ! negative regulation of secretion GO:0051048 68 35 0,000 0,23736968 0,26086106 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,23736968 0,26074377 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,23736968 0,26062658 ! membrane docking GO:0022406 69 35 0,000 0,23736968 0,2605095 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,23736968 0,26039252 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,23736968 0,26027565 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,23736968 0,26015888 ! ceramide metabolic process GO:0006672 72 35 0,000 0,23736968 0,26004221 ! sterol transport GO:0015918 63 35 0,000 0,23736968 0,25992566 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,23736968 0,2598092 ! placenta development GO:0001890 53 35 0,000 0,23736968 0,25969285 ! vesicle localization GO:0051648 70 35 0,000 0,23736968 0,25957661 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,24325441 0,26589285 ! positive regulation of cell development GO:0010720 85 36 0,000 0,24325441 0,26577394 ! protein targeting to membrane GO:0006612 75 36 0,000 0,24325441 0,26565513 ! aerobic respiration GO:0009060 56 36 0,000 0,24325441 0,26553643 ! cytokine production GO:0001816 68 36 0,000 0,24325441 0,26541783 ! embryonic organ development GO:0048568 67 36 0,000 0,24325441 0,26529934 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,24325441 0,26518096 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,24325441 0,26506268 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,24909389 0,27130467 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,24909389 0,27118377 ! odontogenesis GO:0042476 74 37 0,000 0,24909389 0,27106297 ! actomyosin structure organization GO:0031032 68 37 0,000 0,24909389 0,27094229 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,24909389 0,27082171 ! female gonad development GO:0008585 71 37 0,000 0,24909389 0,27070123 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,24909389 0,27058087 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,25488847 0,27675224 ! organic anion transport GO:0015711 82 38 0,000 0,25488847 0,27662929 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,25488847 0,27650646 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,25488847 0,27638373 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,25488847 0,27626111 GO:0006639|acylglycerol metabolic process, ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,25488847 0,2761386 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,25488847 0,2760162 ! spermatid development GO:0007286 69 38 0,000 0,25488847 0,2758939 ! pigment metabolic process GO:0042440 87 38 0,000 0,25488847 0,27577172 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,2606385 0,28186802 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,2606385 0,2817433 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,2606385 0,28161869 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,2606385 0,28149419 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,26634432 0,28752946 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,26634432 0,28740246 ! learning GO:0007612 82 40 0,000 0,26634432 0,28727557 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,26634432 0,2871488 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 75 40 0,000 0,26634432 0,28702213 ! mismatch repair GO:0006298 58 40 0,000 0,26634432 0,28689558 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,26634432 0,28676914 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,26634432 0,28664281 ! RNA export from nucleus GO:0006405 61 41 0,000 0,27200626 0,29260736 ! mRNA catabolic process GO:0006402 79 41 0,000 0,27200626 0,29247857 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,27200626 0,29234989 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,27200626 0,29222133 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,27200626 0,29209288 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,27200626 0,29196455 ! feeding behavior GO:0007631 69 41 0,000 0,27200626 0,29183632 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,27200626 0,29170821 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,27200626 0,29158021 ! spermatid differentiation GO:0048515 73 41 0,000 0,27200626 0,29145233 ! RNA modification GO:0009451 64 41 0,000 0,27200626 0,29132455 ! ear morphogenesis GO:0042471 64 42 0,000 0,27762467 0,29721169 ! organic ether metabolic process GO:0018904 59 42 0,000 0,27762467 0,2970815 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,27762467 0,29695143 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,27762467 0,29682148 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,27762467 0,29669163 ! regulation of protein secretion GO:0050708 77 42 0,000 0,27762467 0,2965619 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,27762467 0,29643229 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,27762467 0,29630278 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,28319987 0,30212109 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,28319987 0,30198921 ! regulation of tube size GO:0035150 76 43 0,000 0,28319987 0,30185746 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,28319987 0,30172581 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,28319987 0,30159429 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,28319987 0,30146287 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,28319987 0,30133157 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,28319987 0,30120039 ! ion transmembrane transport GO:0034220 79 43 0,000 0,28319987 0,30106932 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,28319987 0,30093836 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,2887322 0,30668381 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,2887322 0,30655053 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,2887322 0,30641736 ! striated muscle contraction GO:0006941 85 44 0,000 0,2887322 0,30628431 ! phagocytosis GO:0006909 105 44 0,000 0,2887322 0,30615138 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,2887322 0,30601856 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,29422199 0,31170179 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,29422199 0,31156667 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,29422199 0,31143168 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! biopolymer methylation GO:0043414 91 45 0,000 0,29422199 0,3112968 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,29422199 0,31116204 ! female gamete generation GO:0007292 71 45 0,000 0,29422199 0,3110274 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,29422199 0,31089287 ! developmental growth GO:0048589 88 45 0,000 0,29422199 0,31075846 ! maintenance of location in cell GO:0051651 101 45 0,000 0,29422199 0,31062417 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,29966956 0,31623876 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,29966956 0,31610221 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,29966956 0,31596578 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,30507523 0,32152665 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,31043933 0,32703893 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,31043933 0,32689796 ! endosome transport GO:0016197 127 48 0,000 0,31043933 0,32675712 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,31043933 0,3266164 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,31043933 0,32647579 ! methylation GO:0032259 97 48 0,000 0,31043933 0,32633531 ! response to calcium ion GO:0051592 94 49 0,000 0,31576217 0,33178795 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,31576217 0,3316453 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,31576217 0,33150278 ! regulation of ion transport GO:0043269 86 50 0,000 0,32104407 0,33690321 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,32104407 0,33675855 GO:0019724|B cell mediated immunity, ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,32104407 0,33661402 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,32104407 0,33646961 ! viral infectious cycle GO:0019058 104 51 0,000 0,32628535 0,34181608 ! peptide metabolic process GO:0006518 80 51 0,000 0,32628535 0,34166957 ! response to temperature stimulus GO:0009266 84 51 0,000 0,32628535 0,34152318 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,32628535 0,34137692 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,33148631 0,34666998 ! excretion GO:0007588 87 52 0,000 0,33148631 0,34652164 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,33148631 0,34637342 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,33148631 0,34622534 ! amino acid activation GO:0043038 98 52 0,000 0,33148631 0,34607738 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,33664727 0,35131537 ! inner ear development GO:0048839 89 53 0,000 0,33664727 0,35116537 ! chromatin remodeling GO:0006338 122 53 0,000 0,33664727 0,35101549 ! vesicle organization GO:0016050 127 53 0,000 0,33664727 0,35086574 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,34176853 0,3560514 ! neuromuscular process GO:0050905 107 54 0,000 0,34176853 0,35589963 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,34176853 0,35574799 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,34176853 0,35559648 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,34176853 0,35544509 ! RNA catabolic process GO:0006401 103 55 0,000 0,3468504 0,36057682 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,3468504 0,36042345 ! cell recognition GO:0008037 98 55 0,000 0,3468504 0,36027021 ! cell maturation GO:0048469 107 55 0,000 0,3468504 0,36011709 ! chloride transport GO:0006821 102 57 0,000 0,35689715 0,37039072 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,36186264 0,37538447 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,36186264 0,37522514 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,36186264 0,37506594 ! nuclear export GO:0051168 110 59 0,000 0,36678992 0,38001178 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,3716793 0,38491417 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,3716793 0,38475107 ! adult behavior GO:0030534 104 60 0,000 0,3716793 0,38458811 ! positive regulation of secretion GO:0051047 110 61 0,000 0,37653106 0,38944343 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,37653106 0,38927862 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,37653106 0,38911395 ! proton transport GO:0015992 117 61 0,000 0,37653106 0,38894942 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,38134549 0,39375615 ! tRNA processing GO:0008033 102 62 0,000 0,38134549 0,39358979 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,38612288 0,39835228 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,38612288 0,39818413 ! hydrogen transport GO:0006818 121 64 0,000 0,39086351 0,40290277 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,39086351 0,40273284 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,39556767 0,40740802 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,39556767 0,40723633 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,39556767 0,40706479 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,39556767 0,4068934 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,39556767 0,40672214 ! ear development GO:0043583 114 66 0,000 0,40023563 0,4113486 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,40486766 0,41593427 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,40486766 0,41575944 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,40946406 0,42030281 ! extracellular matrix organization GO:0030198 146 68 0,000 0,40946406 0,42012629 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,40946406 0,41994991 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,41402508 0,42444955 ! developmental maturation GO:0021700 128 69 0,000 0,41402508 0,42427151 ! single fertilization GO:0007338 83 69 0,000 0,41402508 0,42409361 ! cell redox homeostasis GO:0045454 114 70 0,000 0,418551 0,42854992 ! activation of immune response GO:0002253 120 70 0,000 0,418551 0,42837038 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,418551 0,428191 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,4230421 0,43260437 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,4230421 0,43242336 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,42749863 0,43679596 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,42749863 0,43661335 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,42749863 0,4364309 ! humoral immune response GO:0006959 115 73 0,000 0,43192086 0,44076134 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,43192086 0,44057731 ! regulation of immune effector process GO:0002697 156 73 0,000 0,43192086 0,44039343 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,44066347 0,44912009 ! rhythmic process GO:0048511 142 75 0,000 0,44066347 0,4489328 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,44498438 0,45314583 ! regulation of blood pressure GO:0008217 134 76 0,000 0,44498438 0,45295702 ! neurotransmitter transport GO:0006836 142 77 0,000 0,44927203 0,45713101 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,44927203 0,4569407 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,45352667 0,46107601 ! fertilization GO:0009566 99 78 0,000 0,45352667 0,46088422 ! muscle cell differentiation GO:0042692 178 81 0,000 0,4660951 0,4734596 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,47431363 0,48160773 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,47431363 0,48140765 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,47431363 0,48120773 ! response to metal ion GO:0010038 158 84 0,000 0,47837551 0,48512717 ! digestion GO:0007586 130 84 0,000 0,47837551 0,48492588 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,48240611 0,48880884 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,48240611 0,48860619 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,48640568 0,49245299 ! regulation of lyase activity GO:0051339 169 86 0,000 0,48640568 0,49224899 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,49037445 0,49605995 ! nucleosome assembly GO:0006334 126 87 0,000 0,49037445 0,49585463 ! cellular respiration GO:0045333 143 88 0,000 0,49431267 0,49963006 ! sensory perception of smell GO:0007608 117 88 0,000 0,49431267 0,49942343 ! chromatin assembly GO:0031497 128 88 0,000 0,49431267 0,49921697 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,49431267 0,49901068 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,49822057 0,50274797 ! cellular defense response GO:0006968 123 89 0,000 0,49822057 0,5025404 ! response to inorganic substance GO:0010035 173 90 0,000 0,50209837 0,50624281 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,50209837 0,50603396 ! response to unfolded protein GO:0006986 139 90 0,000 0,50209837 0,50582529 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,50594632 0,50949169 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! defense response to bacterium GO:0042742 112 91 0,000 0,50594632 0,50928177 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,50976463 0,51291392 ! vitamin metabolic process GO:0006766 153 93 0,000 0,51355354 0,5165135 ! female pregnancy GO:0007565 166 94 0,000 0,51731328 0,52008079 ! sterol metabolic process GO:0016125 166 94 0,000 0,51731328 0,51986686 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,51731328 0,5196531 ! nucleosome organization GO:0034728 143 95 0,000 0,52104406 0,52318563 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,52104406 0,52297068 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,52104406 0,5227559 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,52104406 0,52254131 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,52104406 0,52232689 ! response to protein stimulus GO:0051789 158 96 0,000 0,5247461 0,52582229 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,52841964 0,52928626 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,53206489 0,53271907 ! mRNA transport GO:0051028 185 100 0,000 0,53927137 0,53971321 ! positive regulation of immune response GO:0050778 175 100 0,000 0,53927137 0,5394922 ! hormone metabolic process GO:0042445 171 100 0,000 0,53927137 0,53927137