pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6306-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! negative regulation of cell-matrix adhesion GO:0001953 36 11 4,000 1,581E-08 3,805E-05 GO:0010812|negative regulation of cell-substrate adhesion, ! cellular response to insulin stimulus GO:0032869 82 37 6,000 1,913E-08 2,302E-05 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 7,000 2,135E-08 1,712E-05 ! phospholipid dephosphorylation GO:0046839 12 5 3,000 2,194E-08 1,32E-05 ! negative regulation of phosphorylation GO:0042326 47 24 5,000 3,406E-08 1,639E-05 ! insulin receptor signaling pathway GO:0008286 64 26 5,000 5,746E-08 2,304E-05 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 5,000 5,746E-08 1,975E-05 GO:0045936|negative regulation of phosphate metabolic process, ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 3,000 6,539E-08 1,967E-05 ! response to insulin stimulus GO:0032868 95 46 6,000 9,342E-08 2,497E-05 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 3,000 1,516E-07 3,647E-05 ! negative regulation of focal adhesion formation GO:0051895 20 7 3,000 1,516E-07 3,316E-05 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 4,000 2,034E-07 4,079E-05 ! regulation of focal adhesion formation GO:0051893 22 8 3,000 3,012E-07 5,575E-05 ! cellular response to hormone stimulus GO:0032870 167 82 7,000 3,861E-07 6,635E-05 ! regulation of protein stability GO:0031647 73 37 5,000 5,38E-07 8,63E-05 ! induction of positive chemotaxis GO:0050930 15 9 3,000 5,387E-07 8,101E-05 ! response to peptide hormone stimulus GO:0043434 122 61 6,000 6,859E-07 9,707E-05 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 3,000 8,92E-07 1,192E-04 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 3,000 8,92E-07 1,13E-04 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 3,000 8,92E-07 1,073E-04 ! regulation of cell-matrix adhesion GO:0001952 78 23 4,000 1,063E-06 1,218E-04 GO:0010810|regulation of cell-substrate adhesion, ! negative regulation of protein kinase activity GO:0006469 130 67 6,000 1,311E-06 1,434E-04 ! negative regulation of glucose import GO:0046325 17 11 3,000 1,393E-06 1,457E-04 GO:0010829|negative regulation of glucose transport, ! negative regulation of kinase activity GO:0033673 131 68 6,000 1,452E-06 1,455E-04 ! induction of apoptosis by intracellular signals GO:0008629 93 45 5,000 1,784E-06 1,717E-04 ! negative regulation of cell migration GO:0030336 115 46 5,000 2,038E-06 1,886E-04 ! regulation of positive chemotaxis GO:0050926 19 12 3,000 2,076E-06 1,85E-04 GO:0050927|positive regulation of positive chemotaxis, ! negative regulation of transferase activity GO:0051348 140 72 6,000 2,145E-06 1,843E-04 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 3,000 4,143E-06 3,438E-04 ! L-serine biosynthetic process GO:0006564 6 5 2,000 5,384E-06 4,318E-04 ! phospholipid scrambling GO:0017121 8 5 2,000 5,384E-06 4,179E-04 ! negative regulation of cell motion GO:0051271 134 55 5,000 5,931E-06 4,459E-04 ! activation of MAPKK activity GO:0000186 35 16 3,000 7,437E-06 5,422E-04 ! regulation of cell adhesion GO:0030155 212 89 6,000 8,915E-06 6,309E-04 ! negative regulation of cell adhesion GO:0007162 81 35 4,000 9,461E-06 6,504E-04 ! endothelial cell migration GO:0043542 28 17 3,000 9,663E-06 6,458E-04 ! inositol metabolic process GO:0006020 28 17 3,000 9,663E-06 6,283E-04 ! cardiac muscle tissue development GO:0048738 31 17 3,000 9,663E-06 6,118E-04 ! activation of MAPKKK activity GO:0000185 12 6 2,000 1,07E-05 6,603E-04 ! androgen receptor signaling pathway GO:0030521 74 36 4,000 1,091E-05 6,565E-04 ! regulation of glucose import GO:0046324 29 20 3,000 1,929E-05 1,132E-03 GO:0010827|regulation of glucose transport, ! positive regulation of locomotion GO:0040017 39 21 3,000 2,368E-05 1,356E-03 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! regulation of caspase activity GO:0043281 122 72 5,000 2,846E-05 1,592E-03 ! regulation of chemotaxis GO:0050920 40 22 3,000 2,876E-05 1,572E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 2,000 2,961E-05 1,583E-03 ! ER overload response GO:0006983 12 8 2,000 2,961E-05 1,548E-03 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 2,000 2,961E-05 1,516E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 2,961E-05 1,484E-03 ! regulation of endopeptidase activity GO:0052548 125 74 5,000 3,328E-05 1,634E-03 ! sex determination GO:0007530 47 23 3,000 3,459E-05 1,664E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 4,000 3,712E-05 1,751E-03 ! regulation of behavior GO:0050795 43 24 3,000 4,124E-05 1,908E-03 ! regulation of developmental growth GO:0048638 15 9 2,000 4,414E-05 2,004E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 2,000 4,414E-05 1,967E-03 ! motor axon guidance GO:0008045 16 9 2,000 4,414E-05 1,931E-03 ! activation of protein kinase activity GO:0032147 147 79 5,000 4,827E-05 2,074E-03 ! regulation of peptidase activity GO:0052547 134 79 5,000 4,827E-05 2,037E-03 ! positive regulation of phosphorylation GO:0042327 129 79 5,000 4,827E-05 2,002E-03 ! vasculogenesis GO:0001570 46 25 3,000 4,877E-05 1,989E-03 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 5,000 5,559E-05 2,229E-03 GO:0045937|positive regulation of phosphate metabolic process, ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 3,000 5,727E-05 2,259E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 2,000 6,267E-05 2,432E-03 ! L-serine metabolic process GO:0006563 18 10 2,000 6,267E-05 2,393E-03 ! negative regulation of protein modification process GO:0031400 60 28 3,000 7,743E-05 2,911E-03 ! peptidyl-tyrosine modification GO:0018212 50 28 3,000 7,743E-05 2,866E-03 ! chondrocyte differentiation GO:0002062 24 11 2,000 8,565E-05 3,122E-03 ! regulation of embryonic development GO:0045995 27 11 2,000 8,565E-05 3,076E-03 ! positive regulation of protein modification process GO:0031401 136 88 5,000 8,85E-05 3,131E-03 ! negative regulation of protein kinase cascade GO:0010741 68 30 3,000 1,023E-04 3,568E-03 ! lipid modification GO:0030258 97 57 4,000 1,054E-04 3,622E-03 ! regulation of B cell proliferation GO:0030888 20 12 2,000 1,135E-04 3,847E-03 ! negative regulation of mast cell proliferation GO:0070667 23 12 2,000 1,135E-04 3,793E-03 GO:0042130|negative regulation of T cell proliferation, ! serine family amino acid metabolic process GO:0009069 49 31 3,000 1,167E-04 3,847E-03 ! positive regulation of MAP kinase activity GO:0043406 160 93 5,000 1,203E-04 3,912E-03 ! interphase of mitotic cell cycle GO:0051329 209 95 5,000 1,353E-04 4,341E-03 ! plasma membrane organization GO:0007009 24 13 2,000 1,467E-04 4,643E-03 ! serine family amino acid biosynthetic process GO:0009070 17 13 2,000 1,467E-04 4,583E-03 ! interphase GO:0051325 213 98 5,000 1,606E-04 4,953E-03 ! steroid hormone receptor signaling pathway GO:0030518 129 63 4,000 1,699E-04 5,176E-03 ! negative regulation of cell growth GO:0030308 132 67 4,000 2,274E-04 6,839E-03 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 4,000 2,274E-04 6,754E-03 ! negative regulation of bone remodeling GO:0046851 33 15 2,000 2,305E-04 6,764E-03 ! regulation of the force of heart contraction GO:0002026 26 15 2,000 2,305E-04 6,682E-03 ! detection of bacterium GO:0016045 18 15 2,000 2,305E-04 6,603E-03 ! epithelial to mesenchymal transition GO:0001837 28 15 2,000 2,305E-04 6,525E-03 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 4,000 2,438E-04 6,821E-03 ! negative regulation of cell size GO:0045792 134 69 4,000 2,611E-04 7,221E-03 ! embryonic forelimb morphogenesis GO:0035115 28 16 2,000 2,82E-04 7,71E-03 ! fructose metabolic process GO:0006000 25 16 2,000 2,82E-04 7,624E-03 ! negative regulation of tissue remodeling GO:0034104 36 16 2,000 2,82E-04 7,539E-03 ! negative regulation of leukocyte proliferation GO:0070664 31 16 2,000 2,82E-04 7,456E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! phosphoinositide metabolic process GO:0030384 128 72 4,000 3,187E-04 8,334E-03 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 4,000 3,187E-04 8,244E-03 ! negative regulation of cell cycle process GO:0010948 32 17 2,000 3,404E-04 8,712E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 3,404E-04 8,62E-03 ! neutrophil chemotaxis GO:0030593 27 17 2,000 3,404E-04 8,53E-03 ! polyol metabolic process GO:0019751 66 41 3,000 3,523E-04 8,738E-03 ! response to retinoic acid GO:0032526 26 18 2,000 4,06E-04 9,967E-03 ! cell-substrate junction assembly GO:0007044 54 18 2,000 4,06E-04 9,866E-03 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 2,000 4,06E-04 9,768E-03 ! positive regulation of response to external stimulus GO:0032103 77 43 3,000 4,238E-04 0,01009657 ! negative regulation of organelle organization GO:0010639 161 78 4,000 4,62E-04 0,01089842 ! protein oligomerization GO:0051259 139 78 4,000 4,62E-04 0,01079261 ! forelimb morphogenesis GO:0035136 32 19 2,000 4,792E-04 0,0110856 ! response to vitamin A GO:0033189 27 19 2,000 4,792E-04 0,01098002 ! glycolysis GO:0006096 65 45 3,000 5,052E-04 0,01146677 ! regulation of gene-specific transcription GO:0032583 96 46 3,000 5,498E-04 0,01236198 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 2,000 5,603E-04 0,012483 ! response to vitamin GO:0033273 31 20 2,000 5,603E-04 0,01236848 ! regulation of carbohydrate metabolic process GO:0006109 38 20 2,000 5,603E-04 0,01225604 GO:0010675|regulation of cellular carbohydrate metabolic process, ! apoptotic mitochondrial changes GO:0008637 41 20 2,000 5,603E-04 0,01214562 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 5,603E-04 0,01203718 ! negative regulation of T cell activation GO:0050868 40 20 2,000 5,603E-04 0,01193066 ! negative regulation of translation GO:0017148 29 20 2,000 5,603E-04 0,011826 ! positive regulation of cell cycle GO:0045787 89 48 3,000 6,472E-04 0,01354026 ! activation of caspase activity GO:0006919 84 48 3,000 6,472E-04 0,01342353 ! regulation of mast cell proliferation GO:0070666 81 48 3,000 6,472E-04 0,0133088 ! negative regulation of transport GO:0051051 153 84 4,000 6,493E-04 0,0132391 ! negative regulation of growth GO:0045926 155 84 4,000 6,493E-04 0,01312784 ! hindlimb morphogenesis GO:0035137 43 21 2,000 6,498E-04 0,01302802 ! inactivation of MAPK activity GO:0000188 39 21 2,000 6,498E-04 0,01292035 ! detection of biotic stimulus GO:0009595 29 21 2,000 6,498E-04 0,01281445 ! positive regulation of inflammatory response GO:0050729 35 21 2,000 6,498E-04 0,01271027 ! cell adhesion mediated by integrin GO:0033627 8 5 1,000 6,591E-04 0,0127884 ! 2-oxoglutarate metabolic process GO:0006103 7 5 1,000 6,591E-04 0,01268609 ! regulation of glycogen metabolic process GO:0070873 11 5 1,000 6,591E-04 0,0125854 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of centrosome cycle GO:0046605 7 5 1,000 6,591E-04 0,01248631 ! meiotic chromosome segregation GO:0045132 7 5 1,000 6,591E-04 0,01238876 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 6,591E-04 0,01229272 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 1,000 6,591E-04 0,01219816 GO:0022011|myelination in the peripheral nervous system, ! stem cell division GO:0017145 11 5 1,000 6,591E-04 0,01210505 GO:0048103|somatic stem cell division, ! cellular anion homeostasis GO:0030002 9 5 1,000 6,591E-04 0,01201334 GO:0055081|anion homeostasis, ! negative regulation of bone resorption GO:0045779 10 5 1,000 6,591E-04 0,01192302 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 6,591E-04 0,01183404 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 1,000 6,591E-04 0,01174638 ! positive regulation of glycolysis GO:0045821 14 5 1,000 6,591E-04 0,01166001 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 1,000 6,591E-04 0,0115749 ! epithelial cell proliferation GO:0050673 9 5 1,000 6,591E-04 0,01149102 ! microvillus organization GO:0032528 7 5 1,000 6,591E-04 0,01140835 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 1,000 6,591E-04 0,01132686 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 6,591E-04 0,01124653 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 1,000 6,591E-04 0,01116733 ! induction of apoptosis by extracellular signals GO:0008624 89 49 3,000 7,002E-04 0,01178123 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 7,478E-04 0,01249504 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 2,000 7,478E-04 0,01240886 ! positive regulation of intracellular transport GO:0032388 37 22 2,000 7,478E-04 0,01232387 ! regulation of leukocyte proliferation GO:0070663 88 51 3,000 8,154E-04 0,01334545 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of angiogenesis GO:0045765 114 52 3,000 8,777E-04 0,01426829 ! positive regulation of growth GO:0045927 90 52 3,000 8,777E-04 0,01417253 ! regulation of cell cycle process GO:0010564 149 90 4,000 8,883E-04 0,01424879 ! response to UV GO:0009411 104 53 3,000 9,433E-04 0,01502996 ! protein import into nucleus, translocation GO:0000060 46 24 2,000 9,71E-04 0,01537064 ! protein tetramerization GO:0051262 52 24 2,000 9,71E-04 0,01527018 ! positive regulation of DNA repair GO:0045739 9 6 1,000 9,833E-04 0,01536212 ! male meiosis GO:0007140 7 6 1,000 9,833E-04 0,01526301 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 1,000 9,833E-04 0,01516517 ! toxin metabolic process GO:0009404 11 6 1,000 9,833E-04 0,01506857 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 1,000 9,833E-04 0,0149732 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! male sex determination GO:0030238 15 6 1,000 9,833E-04 0,01487903 ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 1,000 9,833E-04 0,01478604 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! establishment of spindle localization GO:0051293 12 6 1,000 9,833E-04 0,0146942 GO:0051653|spindle localization, ! astrocyte development GO:0014002 15 6 1,000 9,833E-04 0,01460349 ! Schwann cell development GO:0014044 15 6 1,000 9,833E-04 0,0145139 ! neutrophil homeostasis GO:0001780 10 6 1,000 9,833E-04 0,0144254 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 9,833E-04 0,01433798 ! negative regulation of B cell activation GO:0050869 13 6 1,000 9,833E-04 0,0142516 ! negative regulation of cytoskeleton organization GO:0051494 124 54 3,000 1,012E-03 0,01458359 ! positive regulation of caspase activity GO:0043280 95 55 3,000 1,085E-03 0,01553413 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 3,000 1,085E-03 0,01544222 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 2,000 1,097E-03 0,01552309 ! myelination GO:0042552 45 25 2,000 1,097E-03 0,01543231 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 2,000 1,097E-03 0,01534259 ! response to endoplasmic reticulum stress GO:0034976 43 25 2,000 1,097E-03 0,01525391 ! regulation of DNA replication GO:0006275 101 56 3,000 1,161E-03 0,01604928 ! positive regulation of cell migration GO:0030335 126 57 3,000 1,24E-03 0,01705258 ! regulation of DNA metabolic process GO:0051052 178 97 4,000 1,244E-03 0,01700169 ! positive regulation of protein ubiquitination GO:0031398 12 7 1,000 1,369E-03 0,01861105 ! regulation of helicase activity GO:0051095 15 7 1,000 1,369E-03 0,0185065 ! prostate gland development GO:0030850 13 7 1,000 1,369E-03 0,01840311 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 1,369E-03 0,01830087 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 1,369E-03 0,01819976 ! mRNA stabilization GO:0048255 18 7 1,000 1,369E-03 0,01809976 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 1,000 1,369E-03 0,01800085 ! oxaloacetate metabolic process GO:0006107 10 7 1,000 1,369E-03 0,01790302 ! wound healing, spreading of epidermal cells GO:0035313 14 7 1,000 1,369E-03 0,01780625 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 1,369E-03 0,01771052 ! B cell lineage commitment GO:0002326 21 7 1,000 1,369E-03 0,01761581 ! T cell lineage commitment GO:0002360 16 7 1,000 1,369E-03 0,01752211 ! response to tumor cell GO:0002347 13 7 1,000 1,369E-03 0,0174294 ! regulation of respiratory burst GO:0060263 11 7 1,000 1,369E-03 0,01733766 ! regulation of fibroblast proliferation GO:0048145 52 27 2,000 1,378E-03 0,01735976 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 2,000 1,378E-03 0,01726934 ! negative regulation of lymphocyte activation GO:0051250 53 27 2,000 1,378E-03 0,01717986 ! protein amino acid autophosphorylation GO:0046777 141 60 3,000 1,502E-03 0,01862907 ! negative regulation of response to stimulus GO:0048585 100 60 3,000 1,502E-03 0,01853354 ! ER-nuclear signaling pathway GO:0006984 48 28 2,000 1,534E-03 0,01883287 ! mesoderm development GO:0007498 119 61 3,000 1,597E-03 0,01950784 ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 1,701E-03 0,02066858 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 2,000 1,701E-03 0,02056472 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 1,000 1,816E-03 0,02184232 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 1,000 1,816E-03 0,02173366 ! succinate metabolic process GO:0006105 14 8 1,000 1,816E-03 0,02162606 ! T-helper 1 type immune response GO:0042088 12 8 1,000 1,816E-03 0,02151953 ! negative regulation of endocytosis GO:0045806 11 8 1,000 1,816E-03 0,02141404 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 1,816E-03 0,02130958 ! astrocyte differentiation GO:0048708 18 8 1,000 1,816E-03 0,02120614 ! glycine catabolic process GO:0006546 13 8 1,000 1,816E-03 0,02110369 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 1,816E-03 0,02100223 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 1,816E-03 0,02090175 ! regulation of vascular permeability GO:0043114 12 8 1,000 1,816E-03 0,02080221 ! Schwann cell differentiation GO:0014037 19 8 1,000 1,816E-03 0,02070362 ! regulation of fat cell differentiation GO:0045598 15 8 1,000 1,816E-03 0,02060597 ! myeloid cell homeostasis GO:0002262 13 8 1,000 1,816E-03 0,02050922 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 1,816E-03 0,02041339 ! cell junction assembly GO:0034329 78 30 2,000 1,879E-03 0,02102202 ! positive regulation of multicellular organism growth GO:0040018 51 30 2,000 1,879E-03 0,0209247 ! ensheathment of neurons GO:0007272 57 30 2,000 1,879E-03 0,02082827 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 56 30 2,000 1,879E-03 0,02073273 ! regulation of B cell activation GO:0050864 50 30 2,000 1,879E-03 0,02063806 ! positive regulation of cell motion GO:0051272 146 64 3,000 1,908E-03 0,02086511 ! hexose catabolic process GO:0019320 104 67 3,000 2,258E-03 0,02458187 ! spindle organization GO:0007051 46 32 2,000 2,267E-03 0,02457412 ! regulation of ARF GTPase activity GO:0032312 65 32 2,000 2,267E-03 0,02446392 ! negative regulation of MAP kinase activity GO:0043407 69 32 2,000 2,267E-03 0,02435471 ! peripheral nervous system development GO:0007422 64 32 2,000 2,267E-03 0,02424646 ! positive regulation of catabolic process GO:0009896 64 32 2,000 2,267E-03 0,02413918 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 2,322E-03 0,02460906 ! cell proliferation in forebrain GO:0021846 15 9 1,000 2,322E-03 0,02450112 ! regulation of glycolysis GO:0006110 21 9 1,000 2,322E-03 0,02439413 ! cerebral cortex cell migration GO:0021795 15 9 1,000 2,322E-03 0,02428807 ! microtubule bundle formation GO:0001578 21 9 1,000 2,322E-03 0,02418292 ! phosphagen metabolic process GO:0006599 12 9 1,000 2,322E-03 0,02407869 GO:0006600|creatine metabolic process, ! regulation of Notch signaling pathway GO:0008593 22 9 1,000 2,322E-03 0,02397535 ! protein heterooligomerization GO:0051291 16 9 1,000 2,322E-03 0,02387289 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 1,000 2,322E-03 0,0237713 ! postreplication repair GO:0006301 22 9 1,000 2,322E-03 0,02367057 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 1,000 2,322E-03 0,0235707 ! regulation of synaptogenesis GO:0051963 15 9 1,000 2,322E-03 0,02347166 ! serine family amino acid catabolic process GO:0009071 16 9 1,000 2,322E-03 0,02337345 ! leukocyte chemotaxis GO:0030595 50 33 2,000 2,479E-03 0,02485393 GO:0060326|cell chemotaxis, ! cell cycle checkpoint GO:0000075 137 69 3,000 2,514E-03 0,02510274 ! urogenital system development GO:0001655 137 69 3,000 2,514E-03 0,02499901 ! regulation of striated muscle tissue development GO:0016202 69 34 2,000 2,703E-03 0,02676093 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 2,000 2,703E-03 0,02665125 ! reproductive structure development GO:0048608 113 71 3,000 2,79E-03 0,0274018 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 1,000 2,887E-03 0,0282322 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 2,887E-03 0,0281179 ! SMAD protein nuclear translocation GO:0007184 20 10 1,000 2,887E-03 0,02800452 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 2,887E-03 0,02789206 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 1,000 2,887E-03 0,02778049 ! lung alveolus development GO:0048286 26 10 1,000 2,887E-03 0,02766981 ! pathogenesis GO:0009405 13 10 1,000 2,887E-03 0,02756001 ! negative regulation of striated muscle development GO:0045843 19 10 1,000 2,887E-03 0,02745107 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 2,887E-03 0,027343 ! regulation of bone resorption GO:0045124 25 10 1,000 2,887E-03 0,02723577 ! DNA ligation GO:0006266 19 10 1,000 2,887E-03 0,02712938 ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 2,887E-03 0,02702382 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 2,887E-03 0,02691908 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 2,887E-03 0,02681514 ! localization within membrane GO:0051668 20 10 1,000 2,887E-03 0,02671201 ! regulation of muscle development GO:0048634 70 35 2,000 2,938E-03 0,02708756 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 2,000 2,938E-03 0,02698417 ! regulation of microtubule-based process GO:0032886 78 35 2,000 2,938E-03 0,02688157 ! axon guidance GO:0007411 139 73 3,000 3,086E-03 0,0281262 ! cell junction organization GO:0034330 86 36 2,000 3,186E-03 0,02892938 ! negative regulation of cell activation GO:0050866 65 36 2,000 3,186E-03 0,02882062 ! meiosis GO:0007126 121 74 3,000 3,242E-03 0,02921291 GO:0051327|M phase of meiotic cell cycle, ! meiotic cell cycle GO:0051321 122 75 3,000 3,403E-03 0,03054867 ! tissue remodeling GO:0048771 76 37 2,000 3,447E-03 0,0308278 ! glycogen metabolic process GO:0005977 61 37 2,000 3,447E-03 0,03071362 ! negative regulation of muscle development GO:0048635 20 11 1,000 3,509E-03 0,03115383 ! telencephalon cell migration GO:0022029 20 11 1,000 3,509E-03 0,03103929 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 3,509E-03 0,03092559 ! blood vessel remodeling GO:0001974 29 11 1,000 3,509E-03 0,03081273 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 1,000 3,509E-03 0,03070068 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 3,509E-03 0,03058944 ! regulation of intracellular pH GO:0051453 19 11 1,000 3,509E-03 0,03047901 ! negative regulation of ossification GO:0030279 26 11 1,000 3,509E-03 0,03036938 ! regulation of leukocyte migration GO:0002685 26 11 1,000 3,509E-03 0,03026053 ! regulation of synapse organization GO:0050807 17 11 1,000 3,509E-03 0,03015245 ! steroid biosynthetic process GO:0006694 131 76 3,000 3,569E-03 0,03055911 ! monosaccharide catabolic process GO:0046365 115 76 3,000 3,569E-03 0,03045075 ! positive regulation of DNA metabolic process GO:0051054 72 38 2,000 3,72E-03 0,03162365 ! glucan metabolic process GO:0044042 62 38 2,000 3,72E-03 0,0315123 GO:0006073|cellular glucan metabolic process, ! regulation of action potential in neuron GO:0019228 73 39 2,000 4,005E-03 0,03381464 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 1,000 4,188E-03 0,03523287 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 4,188E-03 0,03511011 ! virus-host interaction GO:0019048 29 12 1,000 4,188E-03 0,0349882 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 4,188E-03 0,03486714 ! focal adhesion formation GO:0048041 35 12 1,000 4,188E-03 0,0347469 ! forebrain cell migration GO:0021885 21 12 1,000 4,188E-03 0,0346275 ! histone acetylation GO:0016573 26 12 1,000 4,188E-03 0,03450891 ! peptidyl-lysine modification GO:0018205 21 12 1,000 4,188E-03 0,03439113 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 1,000 4,188E-03 0,03427416 ! regulation of synapse structure and activity GO:0050803 18 12 1,000 4,188E-03 0,03415797 ! mesenchymal cell development GO:0014031 87 40 2,000 4,304E-03 0,03498698 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of T cell proliferation GO:0042129 71 41 2,000 4,616E-03 0,0373967 ! T cell differentiation GO:0030217 81 41 2,000 4,616E-03 0,03727121 ! regulation of T cell differentiation GO:0045580 70 41 2,000 4,616E-03 0,03714655 ! double-strand break repair via homologous recombination GO:0000724 19 13 1,000 4,923E-03 0,03948183 GO:0000725|recombinational repair, ! lipid localization GO:0010876 28 13 1,000 4,923E-03 0,03935066 GO:0019915|lipid storage, ! negative regulation of lipid metabolic process GO:0045833 19 13 1,000 4,923E-03 0,03922036 ! regulation of skeletal muscle fiber development GO:0048742 32 13 1,000 4,923E-03 0,03909092 ! response to X-ray GO:0010165 25 13 1,000 4,923E-03 0,03896233 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 4,923E-03 0,03883459 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of DNA repair GO:0006282 21 13 1,000 4,923E-03 0,03870768 ! nucleoside triphosphate catabolic process GO:0009143 21 13 1,000 4,923E-03 0,03858159 ! regulation of cellular pH GO:0030641 22 13 1,000 4,923E-03 0,03845633 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 4,923E-03 0,03833188 ! regulation of mRNA stability GO:0043488 31 13 1,000 4,923E-03 0,03820822 ! negative regulation of protein complex disassembly GO:0043242 101 42 2,000 4,942E-03 0,03823018 ! regulation of intracellular protein transport GO:0033157 80 42 2,000 4,942E-03 0,03810765 ! neuron migration GO:0001764 79 42 2,000 4,942E-03 0,0379859 ! hemostasis GO:0007599 158 84 3,000 5,102E-03 0,03909159 ! energy reserve metabolic process GO:0006112 74 43 2,000 5,28E-03 0,04033278 ! regulation of epithelial cell proliferation GO:0050678 111 43 2,000 5,28E-03 0,04020514 ! alcohol catabolic process GO:0046164 130 86 3,000 5,544E-03 0,04207895 ! male sex differentiation GO:0046661 76 44 2,000 5,633E-03 0,04261916 ! double-strand break repair GO:0006302 81 44 2,000 5,633E-03 0,04248556 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 5,712E-03 0,04295075 ! response to gamma radiation GO:0010332 28 14 1,000 5,712E-03 0,04281694 ! regulation of RNA stability GO:0043487 32 14 1,000 5,712E-03 0,04268397 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 5,712E-03 0,04255182 ! leukocyte migration GO:0050900 68 45 2,000 5,999E-03 0,0445498 ! gland development GO:0048732 206 88 3,000 6,011E-03 0,04450215 ! regulation of cell morphogenesis GO:0022604 215 89 3,000 6,254E-03 0,04616012 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 2,000 6,379E-03 0,04693849 ! positive regulation of protein transport GO:0051222 72 46 2,000 6,379E-03 0,04679538 ! sex differentiation GO:0007548 145 90 3,000 6,504E-03 0,04756445 ! regulation of skeletal muscle tissue development GO:0048641 35 15 1,000 6,556E-03 0,0477982 ! embryonic hindlimb morphogenesis GO:0035116 33 15 1,000 6,556E-03 0,0476538 ! heterophilic cell adhesion GO:0007157 39 15 1,000 6,556E-03 0,04751026 ! pituitary gland development GO:0021983 29 15 1,000 6,556E-03 0,04736759 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 6,556E-03 0,04722577 ! G1/S transition checkpoint GO:0031575 40 15 1,000 6,556E-03 0,0470848 ! muscle maintenance GO:0046716 26 15 1,000 6,556E-03 0,04694466 ! positive regulation of defense response GO:0031349 76 47 2,000 6,774E-03 0,0483604 ! regulation of ARF protein signal transduction GO:0032012 102 48 2,000 7,182E-03 0,05112468 ! regulation of inflammatory response GO:0050727 75 48 2,000 7,182E-03 0,05097387 ! regulation of lymphocyte differentiation GO:0045619 81 48 2,000 7,182E-03 0,05082395 ! regulation of protein ubiquitination GO:0031396 25 16 1,000 7,452E-03 0,05258012 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 7,452E-03 0,05242638 ! G1 phase of mitotic cell cycle GO:0000080 35 16 1,000 7,452E-03 0,05227353 ! bone remodeling GO:0046849 27 16 1,000 7,452E-03 0,05212157 ! filopodium assembly GO:0046847 32 16 1,000 7,452E-03 0,0519705 ! induction of apoptosis via death domain receptors GO:0008625 20 16 1,000 7,452E-03 0,05182029 ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 7,452E-03 0,05167095 GO:0031114|regulation of microtubule depolymerization, ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 1,000 7,452E-03 0,05152247 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 7,452E-03 0,05137485 ! DNA replication initiation GO:0006270 27 16 1,000 7,452E-03 0,05122806 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 7,452E-03 0,05108211 ! regulation of action potential GO:0001508 95 49 2,000 7,605E-03 0,05198078 ! regulation of protein complex disassembly GO:0043244 113 49 2,000 7,605E-03 0,05183353 ! DNA-dependent DNA replication GO:0006261 74 49 2,000 7,605E-03 0,05168711 ! forebrain development GO:0030900 188 95 3,000 7,851E-03 0,05321068 ! regulation of gene expression, epigenetic GO:0040029 105 50 2,000 8,042E-03 0,05435114 ! negative regulation of immune system process GO:0002683 95 50 2,000 8,042E-03 0,05419889 ! glial cell development GO:0021782 27 17 1,000 8,4E-03 0,05645607 ! limbic system development GO:0021761 36 17 1,000 8,4E-03 0,05629881 ! glycine metabolic process GO:0006544 28 17 1,000 8,4E-03 0,05614243 ! DNA unwinding during replication GO:0006268 27 17 1,000 8,4E-03 0,05598691 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 1,000 8,4E-03 0,05583225 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 1,000 8,4E-03 0,05567844 ! branched chain family amino acid metabolic process GO:0009081 33 17 1,000 8,4E-03 0,05552548 ! negative regulation of homeostatic process GO:0032845 33 17 1,000 8,4E-03 0,05537335 ! microspike assembly GO:0030035 36 17 1,000 8,4E-03 0,05522206 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 8,4E-03 0,05507159 ! cellular amino acid biosynthetic process GO:0008652 75 51 2,000 8,494E-03 0,05553181 ! regulation of cell shape GO:0008360 125 51 2,000 8,494E-03 0,05538132 ! regulation of muscle contraction GO:0006937 81 52 2,000 8,96E-03 0,05826374 ! cartilage development GO:0051216 90 52 2,000 8,96E-03 0,05810669 ! cell cycle arrest GO:0007050 213 100 3,000 9,37E-03 0,06060044 ! regulation of lipid biosynthetic process GO:0046890 25 18 1,000 9,4E-03 0,0606316 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 9,4E-03 0,06046949 ! memory GO:0007613 31 18 1,000 9,4E-03 0,06030823 ! centrosome cycle GO:0007098 25 18 1,000 9,4E-03 0,06014784 ! positive regulation of proteolysis GO:0045862 31 18 1,000 9,4E-03 0,0599883 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 9,4E-03 0,0598296 ! positive regulation of synaptic transmission GO:0050806 28 18 1,000 9,4E-03 0,05967174 ! cellular polysaccharide metabolic process GO:0044264 86 55 2,000 0,01044743 0,0661487 ! aging GO:0007568 103 55 2,000 0,01044743 0,06597508 ! regulation of multicellular organism growth GO:0040014 85 55 2,000 0,01044743 0,06580237 ! lipid phosphorylation GO:0046834 35 19 1,000 0,01044913 0,06564128 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 1,000 0,01044913 0,06547034 ! cerebral cortex development GO:0021987 36 19 1,000 0,01044913 0,06530028 ! pigmentation during development GO:0048066 41 19 1,000 0,01044913 0,06513111 ! actin filament bundle formation GO:0051017 42 19 1,000 0,01044913 0,06496282 ! neuromuscular junction development GO:0007528 34 19 1,000 0,01044913 0,06479539 ! plasma membrane fusion GO:0045026 28 19 1,000 0,01044913 0,06462882 ! regulation of endothelial cell migration GO:0010594 44 19 1,000 0,01044913 0,0644631 ! peptide cross-linking GO:0018149 37 19 1,000 0,01044913 0,06429823 ! G1 phase GO:0051318 40 19 1,000 0,01044913 0,06413421 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 1,000 0,01044913 0,06397102 ! nucleotide-excision repair GO:0006289 83 56 2,000 0,01097309 0,06700827 ! regulation of bone remodeling GO:0046850 137 57 2,000 0,0115138 0,07013216 ! regulation of intracellular transport GO:0032386 101 57 2,000 0,0115138 0,06995506 ! protein amino acid acetylation GO:0006473 39 20 1,000 0,01154789 0,06998543 ! DNA duplex unwinding GO:0032508 31 20 1,000 0,01154789 0,06980958 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 1,000 0,01154789 0,06963462 ! regulation of fatty acid metabolic process GO:0019217 38 20 1,000 0,01154789 0,06946054 ! diencephalon development GO:0021536 34 20 1,000 0,01154789 0,06928732 ! negative regulation of angiogenesis GO:0016525 45 20 1,000 0,01154789 0,06911496 ! peptidyl-serine modification GO:0018209 43 20 1,000 0,01154789 0,06894346 ! positive regulation of neurological system process GO:0031646 32 20 1,000 0,01154789 0,06877281 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 0,01154789 0,068603 ! regulation of tissue remodeling GO:0034103 140 58 2,000 0,01206962 0,0715259 ! cell structure disassembly during apoptosis GO:0006921 30 21 1,000 0,01269506 0,07504743 ! cell aging GO:0007569 44 21 1,000 0,01269506 0,07486349 ! DNA damage response, signal transduction GO:0042770 128 60 2,000 0,01322686 0,07780888 ! regulation of heart contraction GO:0008016 110 60 2,000 0,01322686 0,07761911 ! positive regulation of protein catabolic process GO:0045732 38 22 1,000 0,01388978 0,08131096 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 1,000 0,01388978 0,08111361 ! apoptotic nuclear changes GO:0030262 32 22 1,000 0,01388978 0,08091721 ! positive regulation of B cell activation GO:0050871 38 22 1,000 0,01388978 0,08072175 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 1,000 0,01388978 0,08052724 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 0,01388978 0,08033367 ! gonad development GO:0008406 98 62 2,000 0,01444527 0,08334607 ! regulation of mitosis GO:0007088 105 63 2,000 0,01507753 0,08678595 GO:0051783|regulation of nuclear division, ! detection of external stimulus GO:0009581 91 63 2,000 0,01507753 0,08657883 ! positive regulation of DNA replication GO:0045740 43 23 1,000 0,0151312 0,08668018 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 1,000 0,0151312 0,08647428 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 0,0151312 0,08626937 ! leukocyte adhesion GO:0007159 50 23 1,000 0,0151312 0,08606542 ! barbed-end actin filament capping GO:0051016 50 23 1,000 0,0151312 0,08586244 GO:0051693|actin filament capping, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 0,0151312 0,08566041 ! platelet activation GO:0030168 37 23 1,000 0,0151312 0,08545933 ! regulation of bone mineralization GO:0030500 49 23 1,000 0,0151312 0,08525919 ! embryonic limb morphogenesis GO:0030326 125 65 2,000 0,01638837 0,09212713 GO:0035113|embryonic appendage morphogenesis, ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 0,01641849 0,09208132 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 0,01641849 0,09186718 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 1,000 0,01641849 0,09165403 ! pallium development GO:0021543 49 24 1,000 0,01641849 0,09144187 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 0,01641849 0,09123068 ! leukocyte homeostasis GO:0001776 44 24 1,000 0,01641849 0,09102048 ! cell projection assembly GO:0030031 120 66 2,000 0,01706702 0,09439827 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 1,000 0,01775081 0,09795516 ! dicarboxylic acid metabolic process GO:0043648 42 25 1,000 0,01775081 0,097731 ! response to starvation GO:0042594 42 25 1,000 0,01775081 0,09750787 ! negative regulation of cell development GO:0010721 73 25 1,000 0,01775081 0,09728576 GO:0050768|negative regulation of neurogenesis, ! regulation of biomineral formation GO:0070167 51 25 1,000 0,01775081 0,09706465 ! negative regulation of DNA replication GO:0008156 42 25 1,000 0,01775081 0,09684455 ! interaction with host GO:0051701 62 25 1,000 0,01775081 0,09662545 ! somitogenesis GO:0001756 43 25 1,000 0,01775081 0,09640733 ! cellular response to nutrient levels GO:0031669 41 25 1,000 0,01775081 0,0961902 ! neural tube closure GO:0001843 49 25 1,000 0,01775081 0,09597404 GO:0060606|tube closure, ! lung development GO:0030324 144 67 2,000 0,01776119 0,09581487 ! chromosome segregation GO:0007059 113 67 2,000 0,01776119 0,09560052 ! activation of MAPK activity GO:0000187 115 67 2,000 0,01776119 0,09538713 ! negative regulation of ligase activity GO:0051352 112 68 2,000 0,01847092 0,0989778 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! negative regulation of actin filament depolymerization GO:0030835 55 26 1,000 0,01912734 0,10226753 ! negative regulation of actin filament polymerization GO:0030837 53 26 1,000 0,01912734 0,10204077 ! tube lumen formation GO:0035148 50 26 1,000 0,01912734 0,10181502 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 0,01912734 0,10159026 ! microtubule organizing center organization GO:0031023 39 26 1,000 0,01912734 0,1013665 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 1,000 0,01912734 0,10114371 ! regulation of cellular ketone metabolic process GO:0010565 44 26 1,000 0,01912734 0,10092191 ! positive regulation of nuclear division GO:0051785 40 26 1,000 0,01912734 0,10070107 GO:0045840|positive regulation of mitosis, ! appendage morphogenesis GO:0035107 135 70 2,000 0,01993709 0,10473503 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 2,000 0,01993709 0,10450685 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 0,02054728 0,10747122 ! protein amino acid acylation GO:0043543 55 27 1,000 0,02054728 0,1072381 ! mitochondrial membrane organization GO:0007006 57 27 1,000 0,02054728 0,10700598 ! male gonad development GO:0008584 44 27 1,000 0,02054728 0,10677487 ! response to toxin GO:0009636 47 27 1,000 0,02054728 0,10654475 ! primary neural tube formation GO:0014020 51 27 1,000 0,02054728 0,10631562 ! base-excision repair GO:0006284 41 27 1,000 0,02054728 0,10608747 ! regulation of chromosome organization GO:0033044 42 27 1,000 0,02054728 0,10586031 ! negative regulation of protein polymerization GO:0032272 55 27 1,000 0,02054728 0,10563411 ! appendage development GO:0048736 136 71 2,000 0,02069357 0,10615933 GO:0060173|limb development, ! respiratory system development GO:0060541 153 72 2,000 0,02146565 0,10988586 ! regulation of actin filament depolymerization GO:0030834 58 28 1,000 0,02200983 0,11243238 ! dendrite development GO:0016358 59 28 1,000 0,02200983 0,11219417 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 1,000 0,02200983 0,11195697 ! learning or memory GO:0007611 147 73 2,000 0,02225334 0,11295684 ! exocytosis GO:0006887 133 74 2,000 0,02305665 0,11678798 ! regulation of transcription factor activity GO:0051090 126 74 2,000 0,02305665 0,11654263 GO:0090046|regulation of transcription regulator activity, ! eye development GO:0001654 143 74 2,000 0,02305665 0,11629831 ! negative regulation of protein complex assembly GO:0031333 59 29 1,000 0,02351419 0,11835806 ! regulation of pH GO:0006885 43 29 1,000 0,02351419 0,11811096 ! cell-matrix adhesion GO:0007160 163 75 2,000 0,02387556 0,11967624 ! phosphoinositide-mediated signaling GO:0048015 131 75 2,000 0,02387556 0,11942743 ! lymphocyte differentiation GO:0030098 167 75 2,000 0,02387556 0,11917965 ! development of primary sexual characteristics GO:0045137 124 76 2,000 0,02471007 0,12308993 ! regulation of catabolic process GO:0009894 161 76 2,000 0,02471007 0,12283561 ! zinc ion transport GO:0006829 45 30 1,000 0,0250596 0,12431628 ! acute-phase response GO:0006953 49 30 1,000 0,0250596 0,12406048 ! blood coagulation GO:0007596 146 78 2,000 0,02642587 0,13055573 GO:0050817|coagulation, ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 1,000 0,02664528 0,13136994 ! mesoderm formation GO:0001707 69 31 1,000 0,02664528 0,13110129 ! negative regulation of transcription regulator activity GO:0090048 58 31 1,000 0,02664528 0,13083374 GO:0043433|negative regulation of transcription factor activity, ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 2,000 0,02730712 0,13381045 ! protein import into nucleus GO:0006606 158 80 2,000 0,02820392 0,13792404 ! metanephros development GO:0001656 74 32 1,000 0,02827046 0,13796904 ! response to ionizing radiation GO:0010212 65 32 1,000 0,02827046 0,13768975 ! regulation of axonogenesis GO:0050770 75 32 1,000 0,02827046 0,13741159 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 0,02827046 0,13713455 ! T cell activation GO:0042110 168 81 2,000 0,02911624 0,14095306 ! response to hypoxia GO:0001666 171 81 2,000 0,02911624 0,14067002 ! cell-substrate adhesion GO:0031589 171 81 2,000 0,02911624 0,14038812 ! nuclear import GO:0051170 161 81 2,000 0,02911624 0,14010734 ! DNA damage checkpoint GO:0000077 71 33 1,000 0,02993442 0,1437569 ! post-embryonic development GO:0009791 69 33 1,000 0,02993442 0,14347053 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 0,02993442 0,1431853 ! formation of primary germ layer GO:0001704 72 33 1,000 0,02993442 0,14290121 ! cell fate specification GO:0001708 52 33 1,000 0,02993442 0,14261823 ! response to drug GO:0042493 143 82 2,000 0,03004406 0,14285771 ! response to nutrient GO:0007584 125 82 2,000 0,03004406 0,14257594 ! response to oxygen levels GO:0070482 176 83 2,000 0,03098735 0,1467629 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 1,000 0,03163639 0,14954256 ! glial cell differentiation GO:0010001 63 34 1,000 0,03163639 0,14924934 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 1,000 0,03163639 0,14895727 ! mesoderm morphogenesis GO:0048332 76 34 1,000 0,03163639 0,14866634 ! regulation of ligase activity GO:0051340 142 84 2,000 0,03194607 0,14982895 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 0,03337566 0,15622928 ! telencephalon development GO:0021537 68 35 1,000 0,03337566 0,15592592 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 0,03337566 0,15562374 ! calcium-mediated signaling GO:0019722 62 35 1,000 0,03337566 0,15532273 ! neural tube formation GO:0001841 67 35 1,000 0,03337566 0,15502288 ! amine biosynthetic process GO:0009309 138 86 2,000 0,0339097 0,15719989 ! mitochondrion organization GO:0007005 148 86 2,000 0,0339097 0,15689758 ! protein localization in nucleus GO:0034504 176 87 2,000 0,03491453 0,16123677 ! regulation of protein transport GO:0051223 154 87 2,000 0,03491453 0,16092789 GO:0070201|regulation of establishment of protein localization, ! mitotic sister chromatid segregation GO:0000070 57 36 1,000 0,03515151 0,16171038 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 1,000 0,03515151 0,16140177 ! DNA integrity checkpoint GO:0031570 75 36 1,000 0,03515151 0,16109434 ! regulation of proteolysis GO:0030162 72 36 1,000 0,03515151 0,16078808 ! regulation of DNA binding GO:0051101 155 88 2,000 0,03593464 0,16405835 ! meiosis I GO:0007127 65 37 1,000 0,03696321 0,16843465 ! sister chromatid segregation GO:0000819 58 37 1,000 0,03696321 0,16811624 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 0,03696321 0,16779904 ! negative regulation of DNA binding GO:0043392 68 37 1,000 0,03696321 0,16748304 ! ossification GO:0001503 188 90 2,000 0,03802055 0,17195008 ! regulation of neuron projection development GO:0010975 91 38 1,000 0,03881008 0,17519146 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 0,03881008 0,17486339 ! carbohydrate homeostasis GO:0033500 53 38 1,000 0,03881008 0,17453654 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 67 38 1,000 0,03881008 0,17421091 ! nucleotide catabolic process GO:0009166 61 38 1,000 0,03881008 0,1738865 ! embryonic epithelial tube formation GO:0001838 72 38 1,000 0,03881008 0,17356329 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 0,03881008 0,17324128 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 1,000 0,03881008 0,17292046 ! bone development GO:0060348 189 91 2,000 0,03908625 0,17382903 ! regulation of defense response GO:0031347 149 92 2,000 0,04016704 0,17830606 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,04034225 0,17875405 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,04034225 0,17842546 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,04034225 0,17809807 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,04034225 0,17777189 ! neuron fate determination GO:0048664 7 5 0,000 0,04034225 0,17744689 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,04034225 0,17712308 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,04034225 0,17680045 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,04034225 0,176479 ! polyol transport GO:0015791 12 5 0,000 0,04034225 0,17615871 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,04034225 0,17583958 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,04034225 0,17552161 ! response to superoxide GO:0000303 10 5 0,000 0,04034225 0,17520478 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,04034225 0,1748891 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,04034225 0,17457455 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,04034225 0,17426113 ! female meiosis GO:0007143 7 5 0,000 0,04034225 0,17394883 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,04034225 0,17363766 ! cobalt ion transport GO:0006824 11 5 0,000 0,04034225 0,17332759 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,04034225 0,17301863 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,04034225 0,17271076 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,04034225 0,172404 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,04034225 0,17209831 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,04034225 0,17179372 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,04034225 0,17149019 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,04034225 0,17118774 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,04034225 0,17088635 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,04034225 0,17058603 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,04034225 0,17028675 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,04034225 0,16998853 ! negative chemotaxis GO:0050919 14 5 0,000 0,04034225 0,16969135 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,04034225 0,1693952 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,04034225 0,16910009 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,04034225 0,168806 ! behavioral response to pain GO:0048266 9 5 0,000 0,04034225 0,16851293 ! clathrin coat assembly GO:0048268 14 5 0,000 0,04034225 0,16822088 ! Notch receptor processing GO:0007220 8 5 0,000 0,04034225 0,16792984 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,04034225 0,16763981 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,04034225 0,16735077 ! micturition GO:0060073 9 5 0,000 0,04034225 0,16706274 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,04034225 0,16677569 ! copulation GO:0007620 9 5 0,000 0,04034225 0,16648962 ! glial cell fate commitment GO:0021781 13 5 0,000 0,04034225 0,16620454 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,04034225 0,16592043 ! spermidine metabolic process GO:0008216 7 5 0,000 0,04034225 0,16563729 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,04034225 0,16535511 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,04034225 0,16507389 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,04034225 0,16479363 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,04034225 0,16451432 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,04034225 0,16423595 ! grooming behavior GO:0007625 6 5 0,000 0,04034225 0,16395853 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,04034225 0,16368204 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,04034225 0,16340648 ! response to protozoan GO:0001562 10 5 0,000 0,04034225 0,16313185 ! lymph vessel development GO:0001945 10 5 0,000 0,04034225 0,16285814 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,04034225 0,16258534 ! endochondral ossification GO:0001958 16 5 0,000 0,04034225 0,16231346 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,04034225 0,16204249 ! parathyroid gland development GO:0060017 13 5 0,000 0,04034225 0,16177242 ! anagen GO:0042640 6 5 0,000 0,04034225 0,16150324 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,04034225 0,16123497 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,04034225 0,16096758 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,04034225 0,16070108 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,04034225 0,16043545 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,04034225 0,16017071 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,04034225 0,15990684 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,04034225 0,15964383 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,04034225 0,15938169 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,04034225 0,15912041 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,04034225 0,15885998 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,04034225 0,15860041 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,04034225 0,15834168 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,04034225 0,15808379 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,04034225 0,15782675 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,04034225 0,15757053 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,04034225 0,15731515 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,04034225 0,1570606 ! histidine catabolic process GO:0006548 6 5 0,000 0,04034225 0,15680686 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,04034225 0,15655395 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,04034225 0,15630185 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,04034225 0,15605056 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,04034225 0,15580008 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,04034225 0,1555504 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,04034225 0,15530152 ! polyol catabolic process GO:0046174 7 5 0,000 0,04034225 0,15505343 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,04034225 0,15480614 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,04034225 0,15455963 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,04034225 0,15431391 ! muscle cell migration GO:0014812 8 5 0,000 0,04034225 0,15406897 ! mitochondrial fission GO:0000266 8 5 0,000 0,04034225 0,1538248 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,04034225 0,15358141 ! mRNA transcription GO:0009299 9 5 0,000 0,04034225 0,15333878 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,04034225 0,15309692 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,04034225 0,15285583 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,04034225 0,15261549 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,04034225 0,1523759 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,04034225 0,15213707 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,04034225 0,15189898 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,04034225 0,15166164 ! response to food GO:0032094 6 5 0,000 0,04034225 0,15142504 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,04034225 0,15118917 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,04034225 0,15095404 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,04034225 0,15071964 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,04034225 0,15048597 ! forebrain neuron development GO:0021884 13 5 0,000 0,04034225 0,15025302 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,04034225 0,15002079 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,04034225 0,14978927 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,04034225 0,14955847 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,04034225 0,14932838 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,04034225 0,149099 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,04034225 0,14887032 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,04034225 0,14864234 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,04034225 0,14841506 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,04034225 0,14818847 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,04034225 0,14796258 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,04034225 0,14773737 ! basic amino acid transport GO:0015802 11 5 0,000 0,04034225 0,14751284 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,04034225 0,147289 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,04034225 0,14706583 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,04034225 0,14684334 ! depyrimidination GO:0045008 10 5 0,000 0,04034225 0,14662152 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,04034225 0,14640038 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,04034225 0,14617989 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,04034225 0,14596007 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,04034225 0,14574091 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,04034225 0,14552241 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,04034225 0,14530456 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,04034225 0,14508737 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,04034225 0,14487082 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,04034225 0,14465492 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,04034225 0,14443966 ! response to arsenic GO:0046685 10 5 0,000 0,04034225 0,14422504 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,04034225 0,14401105 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,04034225 0,1437977 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,04034225 0,14358498 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,04034225 0,14337289 ! response to cadmium ion GO:0046686 7 5 0,000 0,04034225 0,14316143 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,04034225 0,14295059 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,04034225 0,14274037 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,04034225 0,14253076 ! decidualization GO:0046697 11 5 0,000 0,04034225 0,14232177 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,04034225 0,1421134 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,04034225 0,14190563 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,04034225 0,14169847 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,04034225 0,14149191 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,04034225 0,14128595 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,04034225 0,14108059 ! neural tube patterning GO:0021532 7 5 0,000 0,04034225 0,14087583 ! embryonic cleavage GO:0040016 6 5 0,000 0,04034225 0,14067167 ! peroxisome fission GO:0016559 5 5 0,000 0,04034225 0,14046809 ! histone demethylation GO:0016577 10 5 0,000 0,04034225 0,1402651 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,04034225 0,1400627 ! mitotic recombination GO:0006312 9 5 0,000 0,04034225 0,13986088 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,04034225 0,13965964 ! metaphase plate congression GO:0051310 7 5 0,000 0,04034225 0,13945898 ! regulation of sterol transport GO:0032371 7 5 0,000 0,04034225 0,13925889 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,04034225 0,13905938 ! enteric nervous system development GO:0048484 8 5 0,000 0,04034225 0,13886044 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,04034225 0,13866207 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,04034225 0,13846426 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,04034225 0,13826702 ! muscle cell proliferation GO:0033002 11 5 0,000 0,04034225 0,13807034 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,04034225 0,13787422 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,04034225 0,13767865 ! plasminogen activation GO:0031639 5 5 0,000 0,04034225 0,13748364 ! B cell homeostasis GO:0001782 13 5 0,000 0,04034225 0,13728918 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,04034225 0,13709527 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,04034225 0,1369019 ! metaphase GO:0051323 8 5 0,000 0,04034225 0,13670908 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,04034225 0,13651681 ! cellular response to nutrient GO:0031670 8 5 0,000 0,04034225 0,13632507 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,04034225 0,13613387 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,04034225 0,13594321 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,04034225 0,13575308 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,04034225 0,13556348 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,04034225 0,13537441 ! response to redox state GO:0051775 5 5 0,000 0,04034225 0,13518586 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,04034225 0,13499784 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,04034225 0,13481035 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,04034225 0,13462337 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,04034225 0,13443691 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,04034225 0,13425097 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,04034225 0,13406554 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,04034225 0,13388062 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,04034225 0,13369621 ! striatum development GO:0021756 9 5 0,000 0,04034225 0,13351231 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,04034225 0,13332891 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,04034225 0,13314602 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,04034225 0,13296363 ! glial cell migration GO:0008347 11 5 0,000 0,04034225 0,13278174 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,04034225 0,13260034 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,04034225 0,13241944 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,04034225 0,13223903 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,04034225 0,13205911 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,04034225 0,13187969 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,04034225 0,13170075 ! neuroprotection GO:0043526 6 5 0,000 0,04034225 0,13152229 ! neural plate development GO:0001840 8 5 0,000 0,04034225 0,13134432 ! regulation of sensory perception GO:0051931 7 5 0,000 0,04034225 0,13116682 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,04034225 0,13098981 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,04034225 0,13081327 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,04034225 0,13063721 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,04034225 0,13046163 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,04034225 0,13028651 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,04034225 0,13011186 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,04034225 0,12993768 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,04034225 0,12976397 ! spindle assembly GO:0051225 6 5 0,000 0,04034225 0,12959072 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,04034225 0,12941793 GO:0016226|iron-sulfur cluster assembly, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,04034225 0,1292456 ! drug metabolic process GO:0017144 6 5 0,000 0,04034225 0,12907374 ! organ regeneration GO:0031100 7 5 0,000 0,04034225 0,12890232 ! carnitine metabolic process GO:0009437 7 5 0,000 0,04034225 0,12873137 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,04034225 0,12856086 ! mammary gland development GO:0030879 86 39 1,000 0,04069141 0,12950202 ! development of primary male sexual characteristics GO:0046546 66 39 1,000 0,04069141 0,12933095 ! segmentation GO:0035282 67 39 1,000 0,04069141 0,12916033 ! regulation of membrane potential GO:0042391 164 93 2,000 0,04126286 0,13080165 ! negative regulation of multicellular organismal process GO:0051241 166 93 2,000 0,04126286 0,13062954 ! regulation of T cell activation GO:0050863 158 94 2,000 0,04237368 0,13396986 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 1,000 0,04260652 0,13452925 ! negative regulation of binding GO:0051100 72 40 1,000 0,04260652 0,13435293 ! multicellular organismal metabolic process GO:0044236 57 40 1,000 0,04260652 0,13417707 ! cytokinesis GO:0000910 72 40 1,000 0,04260652 0,13400168 ! cellular amide metabolic process GO:0043603 67 41 1,000 0,04455474 0,13994607 ! gliogenesis GO:0042063 88 41 1,000 0,04455474 0,13976362 ! keratinocyte differentiation GO:0030216 62 41 1,000 0,04455474 0,13958163 ! leukocyte differentiation GO:0002521 202 96 2,000 0,04464001 0,13966692 ! detection of stimulus GO:0051606 151 96 2,000 0,04464001 0,13948554 ! regulation of protein localization GO:0032880 176 97 2,000 0,04579541 0,14291019 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,04653539 0,14503128 GO:0090047|positive regulation of transcription regulator activity, ! skeletal muscle tissue development GO:0007519 186 99 2,000 0,04815035 0,14987029 GO:0060538|skeletal muscle organ development, ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,04821404 0,14987466 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,04821404 0,14968127 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,04821404 0,14948838 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,04821404 0,14929599 GO:0030816|positive regulation of cAMP metabolic process, ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,04821404 0,1491041 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,04821404 0,14891269 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,04821404 0,14872178 ! sleep GO:0030431 13 6 0,000 0,04821404 0,14853135 ! response to oxygen radical GO:0000305 11 6 0,000 0,04821404 0,14834141 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,04821404 0,14815196 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,04821404 0,14796299 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,04821404 0,1477745 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,04821404 0,1475865 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,04821404 0,14739897 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,04821404 0,14721191 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,04821404 0,14702533 ! forebrain regionalization GO:0021871 8 6 0,000 0,04821404 0,14683922 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,04821404 0,14665359 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,04821404 0,14646842 ! response to zinc ion GO:0010043 9 6 0,000 0,04821404 0,14628372 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,04821404 0,14609948 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,04821404 0,14591571 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,04821404 0,14573239 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,04821404 0,14554954 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,04821404 0,14536715 ! malate metabolic process GO:0006108 11 6 0,000 0,04821404 0,14518521 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,04821404 0,14500373 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,04821404 0,1448227 ! protein refolding GO:0042026 15 6 0,000 0,04821404 0,14464213 ! opsonization GO:0008228 8 6 0,000 0,04821404 0,144462 ! mating behavior GO:0007617 7 6 0,000 0,04821404 0,14428232 ! neuron remodeling GO:0016322 15 6 0,000 0,04821404 0,14410309 ! erythrocyte maturation GO:0043249 7 6 0,000 0,04821404 0,1439243 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,04821404 0,14374596 ! equilibrioception GO:0050957 14 6 0,000 0,04821404 0,14356805 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,04821404 0,14339059 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,04821404 0,14321356 ! photoreceptor cell development GO:0042461 10 6 0,000 0,04821404 0,14303697 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,04821404 0,14286082 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,04821404 0,1426851 ! response to interferon-gamma GO:0034341 15 6 0,000 0,04821404 0,14250981 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,04821404 0,14233495 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,04821404 0,14216052 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,04821404 0,14198652 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,04821404 0,14181294 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,04821404 0,14163979 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,04821404 0,14146706 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,04821404 0,14129475 ! thymic T cell selection GO:0045061 12 6 0,000 0,04821404 0,14112285 ! protein lipoylation GO:0009249 10 6 0,000 0,04821404 0,14095138 ! cysteine metabolic process GO:0006534 10 6 0,000 0,04821404 0,14078032 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,04821404 0,14060968 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,04821404 0,14043945 ! glutamate catabolic process GO:0006538 10 6 0,000 0,04821404 0,14026963 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,04821404 0,14010022 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! adenohypophysis development GO:0021984 10 6 0,000 0,04821404 0,13993123 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,04821404 0,13976263 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,04821404 0,13959445 ! hyperosmotic response GO:0006972 9 6 0,000 0,04821404 0,13942667 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,04821404 0,13925929 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,04821404 0,13909231 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,04821404 0,13892573 ! urea metabolic process GO:0019627 7 6 0,000 0,04821404 0,13875955 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,04821404 0,13859377 ! neutrophil activation GO:0042119 8 6 0,000 0,04821404 0,13842838 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,04821404 0,13826339 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,04821404 0,13809879 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,04821404 0,13793459 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,04821404 0,13777077 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,04821404 0,13760734 ! neuron apoptosis GO:0051402 9 6 0,000 0,04821404 0,1374443 ! nucleoside salvage GO:0043174 9 6 0,000 0,04821404 0,13728164 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,04821404 0,13711937 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,04821404 0,13695748 ! T cell mediated immunity GO:0002456 16 6 0,000 0,04821404 0,13679597 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,04821404 0,13663485 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,04821404 0,1364741 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,04821404 0,13631373 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,04821404 0,13615374 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,04821404 0,13599412 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,04821404 0,13583488 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,04821404 0,13567601 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,04821404 0,13551751 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,04821404 0,13535938 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,04821404 0,13520162 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,04821404 0,13504422 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,04821404 0,13488719 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,04821404 0,13473053 ! neural nucleus development GO:0048857 14 6 0,000 0,04821404 0,13457423 ! response to UV-C GO:0010225 11 6 0,000 0,04821404 0,13441829 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,04821404 0,13426272 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,04821404 0,1341075 ! interaction with symbiont GO:0051702 13 6 0,000 0,04821404 0,13395264 ! regulation of dendrite development GO:0050773 16 6 0,000 0,04821404 0,13379814 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,04821404 0,13364399 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,04821404 0,1334902 ! response to copper ion GO:0046688 10 6 0,000 0,04821404 0,13333677 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,04821404 0,13318368 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,04821404 0,13303095 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,04821404 0,13287856 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,04821404 0,13272653 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,04821404 0,13257484 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,04821404 0,1324235 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,04821404 0,1322725 ! hair follicle maturation GO:0048820 7 6 0,000 0,04821404 0,13212185 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,04821404 0,13197154 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,04821404 0,13182158 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,04821404 0,13167195 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,04821404 0,13152266 ! subpallium development GO:0021544 10 6 0,000 0,04821404 0,13137371 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,04821404 0,1312251 ! histone ubiquitination GO:0016574 8 6 0,000 0,04821404 0,13107682 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,04821404 0,13092888 ! maintenance of organ identity GO:0048496 9 6 0,000 0,04821404 0,13078127 ! G2 phase GO:0051319 16 6 0,000 0,04821404 0,13063399 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,04821404 0,13048705 ! establishment of planar polarity GO:0001736 7 6 0,000 0,04821404 0,13034043 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,04821404 0,13019415 ! membrane to membrane docking GO:0022614 14 6 0,000 0,04821404 0,13004819 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,04821404 0,12990256 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,04821404 0,12975726 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,04821404 0,12961227 ! receptor internalization GO:0031623 10 6 0,000 0,04821404 0,12946762 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,04821404 0,12932328 GO:0031272|regulation of pseudopodium assembly, ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,04821404 0,12917927 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,04821404 0,12903558 ! protein deubiquitination GO:0016579 14 6 0,000 0,04821404 0,12889221 ! protein destabilization GO:0031648 9 6 0,000 0,04821404 0,12874915 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,04821404 0,12860641 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,04821404 0,12846399 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,04821404 0,12832189 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,04821404 0,1281801 ! progesterone metabolic process GO:0042448 10 6 0,000 0,04821404 0,12803862 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,04821404 0,12789745 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,04821404 0,12775659 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,04821404 0,12761605 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,04821404 0,12747581 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,04821404 0,12733588 ! determination of adult lifespan GO:0008340 15 6 0,000 0,04821404 0,12719626 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,04821404 0,12705694 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,04821404 0,12691793 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,04821404 0,12677922 ! catecholamine transport GO:0051937 9 6 0,000 0,04821404 0,12664081 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,04821404 0,12650271 ! sensory cilium assembly GO:0035058 10 6 0,000 0,04821404 0,12636491 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,04821404 0,12622741 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,04821404 0,1260902 ! maternal placenta development GO:0001893 12 6 0,000 0,04821404 0,1259533 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,04821404 0,12581669 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,04821404 0,12568037 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,04821404 0,12554436 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,04821404 0,12540863 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,04821404 0,1252732 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,04821404 0,12513806 ! neural tube development GO:0021915 77 43 1,000 0,04854782 0,12586861 ! epithelial cell differentiation GO:0030855 79 43 1,000 0,04854782 0,12573312 ! glucose transport GO:0015758 65 43 1,000 0,04854782 0,12559792 ! hexose transport GO:0008645 67 44 1,000 0,05059139 0,13074424 GO:0015749|monosaccharide transport, ! B cell differentiation GO:0030183 107 44 1,000 0,05059139 0,13060395 ! JAK-STAT cascade GO:0007259 71 44 1,000 0,05059139 0,13046397 ! regulation of actin filament polymerization GO:0030833 87 45 1,000 0,05266544 0,13566709 ! regulation of JAK-STAT cascade GO:0046425 70 45 1,000 0,05266544 0,13552199 ! cell growth GO:0016049 84 45 1,000 0,05266544 0,1353772 ! epidermal cell differentiation GO:0009913 68 46 1,000 0,05476935 0,14063508 ! pigmentation GO:0043473 100 46 1,000 0,05476935 0,14048515 ! tRNA transcription GO:0009304 14 7 0,000 0,05602153 0,14354397 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,05602153 0,14339127 GO:0045346|regulation of MHC class II biosynthetic process, ! behavioral response to cocaine GO:0048148 14 7 0,000 0,05602153 0,14323889 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,05602153 0,14308683 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,05602153 0,14293509 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,05602153 0,14278368 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,05602153 0,14263258 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,05602153 0,14248181 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,05602153 0,14233135 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,05602153 0,14218121 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,05602153 0,14203139 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,05602153 0,14188189 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,05602153 0,14173269 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,05602153 0,14158381 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,05602153 0,14143525 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,05602153 0,14128699 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,05602153 0,14113905 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,05602153 0,14099141 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,05602153 0,14084409 ! glycolipid transport GO:0046836 10 7 0,000 0,05602153 0,14069707 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,05602153 0,14055036 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,05602153 0,14040395 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,05602153 0,14025785 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,05602153 0,14011205 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,05602153 0,13996655 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,05602153 0,13982136 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,05602153 0,13967647 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,05602153 0,13953187 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,05602153 0,13938758 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,05602153 0,13924359 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,05602153 0,13909989 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,05602153 0,13895649 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,05602153 0,13881338 ! lipoprotein transport GO:0042953 14 7 0,000 0,05602153 0,13867057 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,05602153 0,13852805 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,05602153 0,13838582 ! rhythmic behavior GO:0007622 15 7 0,000 0,05602153 0,13824389 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,05602153 0,13810224 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,05602153 0,13796089 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,05602153 0,13781983 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,05602153 0,13767905 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,05602153 0,13753856 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,05602153 0,13739836 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,05602153 0,13725844 ! mechanosensory behavior GO:0007638 14 7 0,000 0,05602153 0,13711881 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,05602153 0,13697946 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,05602153 0,1368404 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,05602153 0,13670161 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,05602153 0,13656311 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,05602153 0,13642489 ! spinal cord patterning GO:0021511 13 7 0,000 0,05602153 0,13628695 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,05602153 0,13614928 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,05602153 0,1360119 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,05602153 0,13587479 ! adrenal gland development GO:0030325 17 7 0,000 0,05602153 0,13573796 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,05602153 0,1356014 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,05602153 0,13546512 ! ovulation GO:0030728 9 7 0,000 0,05602153 0,13532911 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,05602153 0,13519337 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,05602153 0,13505791 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,05602153 0,13492271 ! microtubule nucleation GO:0007020 20 7 0,000 0,05602153 0,13478779 ! proline biosynthetic process GO:0006561 10 7 0,000 0,05602153 0,13465314 ! thyroid hormone generation GO:0006590 13 7 0,000 0,05602153 0,13451875 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,05602153 0,13438464 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,05602153 0,13425079 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,05602153 0,1341172 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,05602153 0,13398389 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,05602153 0,13385084 ! galactose metabolic process GO:0006012 13 7 0,000 0,05602153 0,13371805 ! vesicle fusion GO:0006906 17 7 0,000 0,05602153 0,13358552 ! response to dietary excess GO:0002021 8 7 0,000 0,05602153 0,13345326 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,05602153 0,13332126 ! intracellular pH reduction GO:0051452 11 7 0,000 0,05602153 0,13318952 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,05602153 0,13305804 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,05602153 0,13292682 ! organ growth GO:0035265 15 7 0,000 0,05602153 0,13279585 ! purine salvage GO:0043101 10 7 0,000 0,05602153 0,13266515 ! nucleoside transport GO:0015858 8 7 0,000 0,05602153 0,1325347 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,05602153 0,13240451 ! parturition GO:0007567 14 7 0,000 0,05602153 0,13227457 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,05602153 0,13214489 ! rRNA modification GO:0000154 14 7 0,000 0,05602153 0,13201547 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,05602153 0,13188629 ! spindle checkpoint GO:0031577 15 7 0,000 0,05602153 0,13175737 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,05602153 0,1316287 ! macrophage differentiation GO:0030225 11 7 0,000 0,05602153 0,13150028 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,05602153 0,13137212 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,05602153 0,1312442 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,05602153 0,13111653 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,05602153 0,13098911 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,05602153 0,13086193 ! fibrinolysis GO:0042730 10 7 0,000 0,05602153 0,13073501 ! eating behavior GO:0042755 7 7 0,000 0,05602153 0,13060832 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,05602153 0,13048189 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,05602153 0,1303557 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,05602153 0,13022975 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,05602153 0,13010405 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,05602153 0,12997858 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,05602153 0,12985336 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,05602153 0,12972838 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,05602153 0,12960365 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,05602153 0,12947915 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,05602153 0,12935489 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,05602153 0,12923086 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,05602153 0,12910708 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,05602153 0,12898353 ! regulation of meiosis GO:0040020 12 7 0,000 0,05602153 0,12886022 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,05602153 0,12873715 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,05602153 0,1286143 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,05602153 0,1284917 ! oxygen homeostasis GO:0032364 12 7 0,000 0,05602153 0,12836932 ! transcription termination GO:0006353 13 7 0,000 0,05602153 0,12824718 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,05602153 0,12812528 ! anaphase GO:0051322 17 7 0,000 0,05602153 0,1280036 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,05602153 0,12788215 ! axonal fasciculation GO:0007413 18 7 0,000 0,05602153 0,12776094 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,05602153 0,12763995 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,05602153 0,1275192 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,05602153 0,12739867 ! diuresis GO:0030146 12 7 0,000 0,05602153 0,12727837 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,05602153 0,12715829 ! thiamin metabolic process GO:0006772 7 7 0,000 0,05602153 0,12703845 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,05602153 0,12691882 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,05602153 0,12679943 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,05602153 0,12668025 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,05602153 0,12656131 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,05602153 0,12644258 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,05602153 0,12632408 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,05602153 0,1262058 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,05602153 0,12608774 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,05602153 0,1259699 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,05602153 0,12585228 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,05602153 0,12573488 ! lymph node development GO:0048535 10 7 0,000 0,05602153 0,1256177 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,05602153 0,12550074 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,05602153 0,12538399 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,05602153 0,12526746 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,05602153 0,12515115 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,05602153 0,12503506 ! adult feeding behavior GO:0008343 9 7 0,000 0,05602153 0,12491918 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,05602153 0,12480351 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,05602153 0,12468806 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,05602153 0,12457282 ! muscle adaptation GO:0043500 14 7 0,000 0,05602153 0,12445779 ! embryonic heart tube development GO:0035050 10 7 0,000 0,05602153 0,12434298 ! retina homeostasis GO:0001895 12 7 0,000 0,05602153 0,12422838 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,05602153 0,12411399 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,05602153 0,12399981 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,05602153 0,12388584 ! protein prenylation GO:0018342 18 7 0,000 0,05602153 0,12377208 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,05602153 0,12365852 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,05602153 0,12354518 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,05602153 0,12343204 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,0569025 0,12525838 ! vascular process in circulatory system GO:0003018 80 47 1,000 0,0569025 0,12514388 ! JNK cascade GO:0007254 91 47 1,000 0,0569025 0,12502959 ! protein homooligomerization GO:0051260 76 47 1,000 0,0569025 0,12491552 ! mitochondrial transport GO:0006839 82 48 1,000 0,05906425 0,12954293 ! Notch signaling pathway GO:0007219 96 48 1,000 0,05906425 0,12942495 ! cellular component disassembly GO:0022411 86 48 1,000 0,05906425 0,12930718 ! morphogenesis of embryonic epithelium GO:0016331 91 48 1,000 0,05906425 0,12918963 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 1,000 0,06125401 0,13385755 ! endocrine system development GO:0035270 104 49 1,000 0,06125401 0,13373608 ! regulation of cell projection organization GO:0031344 121 50 1,000 0,06347118 0,13845119 ! regulation of ossification GO:0030278 117 50 1,000 0,06347118 0,13832578 ! histone modification GO:0016570 91 50 1,000 0,06347118 0,1382006 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,06376522 0,1387153 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,06376522 0,13858999 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,06376522 0,13846491 GO:0016446|somatic hypermutation of immunoglobulin genes, ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,06376522 0,13834006 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,06376522 0,13821543 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,06376522 0,13809102 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,06376522 0,13796684 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,06376522 0,13784288 ! meiotic prophase I GO:0007128 13 8 0,000 0,06376522 0,13771914 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,06376522 0,13759563 ! oligopeptide transport GO:0006857 15 8 0,000 0,06376522 0,13747233 ! UTP metabolic process GO:0046051 8 8 0,000 0,06376522 0,13734926 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,06376522 0,13722641 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,06376522 0,13710377 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,06376522 0,13698136 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,06376522 0,13685916 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,06376522 0,13673719 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,06376522 0,13661543 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,06376522 0,13649388 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,06376522 0,13637255 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,06376522 0,13625144 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,06376522 0,13613054 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,06376522 0,13600986 ! reflex GO:0060004 16 8 0,000 0,06376522 0,13588939 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,06376522 0,13576914 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,06376522 0,13564909 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,06376522 0,13552926 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,06376522 0,13540964 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,06376522 0,13529023 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,06376522 0,13517103 ! pigment granule organization GO:0048753 16 8 0,000 0,06376522 0,13505205 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,06376522 0,13493327 ! histidine metabolic process GO:0006547 16 8 0,000 0,06376522 0,1348147 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,06376522 0,13469633 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,06376522 0,13457818 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,06376522 0,13446023 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,06376522 0,13434249 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,06376522 0,13422495 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,06376522 0,13410763 ! melanin metabolic process GO:0006582 15 8 0,000 0,06376522 0,1339905 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,06376522 0,13387358 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,06376522 0,13375686 ! macrophage activation GO:0042116 12 8 0,000 0,06376522 0,13364035 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,06376522 0,13352404 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,06376522 0,13340793 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,06376522 0,13329203 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,06376522 0,13317632 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,06376522 0,13306082 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,06376522 0,13294551 ! osteoblast development GO:0002076 16 8 0,000 0,06376522 0,13283041 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,06376522 0,1327155 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,06376522 0,1326008 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,06376522 0,13248629 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,06376522 0,13237198 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,06376522 0,13225786 ! response to UV-B GO:0010224 16 8 0,000 0,06376522 0,13214395 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,06376522 0,13203023 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,06376522 0,1319167 ! intermediate filament organization GO:0045109 12 8 0,000 0,06376522 0,13180337 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,06376522 0,13169023 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,06376522 0,13157729 ! cellular extravasation GO:0045123 12 8 0,000 0,06376522 0,13146454 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,06376522 0,13135199 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,06376522 0,13123963 ! response to antibiotic GO:0046677 11 8 0,000 0,06376522 0,13112746 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,06376522 0,13101548 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,06376522 0,13090369 ! DNA topological change GO:0006265 12 8 0,000 0,06376522 0,13079209 ! response to tropane GO:0014073 15 8 0,000 0,06376522 0,13068068 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,06376522 0,13056947 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,06376522 0,13045844 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,06376522 0,1303476 ! mast cell activation GO:0045576 14 8 0,000 0,06376522 0,13023695 ! multicellular organismal aging GO:0010259 18 8 0,000 0,06376522 0,13012648 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,06376522 0,13001621 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,06376522 0,12990612 ! nucleosome disassembly GO:0006337 14 8 0,000 0,06376522 0,12979621 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,06376522 0,12968649 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,06376522 0,12957696 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,06376522 0,12946761 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,06376522 0,12935845 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,06376522 0,12924947 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,06376522 0,12914068 ! intracellular lipid transport GO:0032365 13 8 0,000 0,06376522 0,12903206 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,06376522 0,12892363 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,06376522 0,12881538 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,06376522 0,12870732 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,06376522 0,12859943 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,06376522 0,12849173 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,06376522 0,1283842 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,06376522 0,12827686 ! hormone catabolic process GO:0042447 17 8 0,000 0,06376522 0,12816969 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,06376522 0,12806271 GO:0010828|positive regulation of glucose transport, ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,06376522 0,1279559 ! ATP catabolic process GO:0006200 11 8 0,000 0,06376522 0,12784927 ! blastocyst growth GO:0001832 19 8 0,000 0,06376522 0,12774282 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,06376522 0,12763654 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,06376522 0,12753044 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,06376522 0,12742452 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,06376522 0,12731877 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,06376522 0,1272132 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,06376522 0,12710781 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,06376522 0,12700259 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,06376522 0,12689754 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,06376522 0,12679266 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,06376522 0,12668796 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,06376522 0,12658344 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,06376522 0,12647908 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,06376522 0,1263749 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,06376522 0,12627088 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,06376522 0,12616704 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,06376522 0,12606337 ! positive regulation of binding GO:0051099 78 51 1,000 0,06571516 0,12981173 ! response to estrogen stimulus GO:0043627 93 51 1,000 0,06571516 0,12970524 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 1,000 0,06571516 0,12959892 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 1,000 0,06571516 0,12949278 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 1,000 0,06571516 0,12938681 ! epithelial tube morphogenesis GO:0060562 98 51 1,000 0,06571516 0,12928102 ! membrane fusion GO:0006944 110 52 1,000 0,06798537 0,13363792 ! covalent chromatin modification GO:0016569 101 52 1,000 0,06798537 0,13352882 ! synapse organization GO:0050808 85 52 1,000 0,06798537 0,13341991 ! regulation of translational initiation GO:0006446 82 53 1,000 0,07028123 0,13781308 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 1,000 0,07028123 0,13770085 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,07028123 0,13758881 ! regulation of protein polymerization GO:0032271 103 53 1,000 0,07028123 0,13747695 ! axon extension GO:0048675 15 9 0,000 0,07144565 0,13964113 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,07144565 0,13952779 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,07144565 0,13941462 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,07144565 0,13930165 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,07144565 0,13918885 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,07144565 0,13907624 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,07144565 0,13896381 ! phosphate transport GO:0006817 19 9 0,000 0,07144565 0,13885156 ! reproductive behavior GO:0019098 19 9 0,000 0,07144565 0,13873949 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,07144565 0,13862761 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,07144565 0,1385159 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,07144565 0,13840437 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,07144565 0,13829303 ! GTP metabolic process GO:0046039 9 9 0,000 0,07144565 0,13818186 ! RNA methylation GO:0001510 15 9 0,000 0,07144565 0,13807087 ! elastic fiber assembly GO:0048251 15 9 0,000 0,07144565 0,13796006 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,07144565 0,13784942 ! artery development GO:0060840 24 9 0,000 0,07144565 0,13773897 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,07144565 0,13762869 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,07144565 0,13751859 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,07144565 0,13740866 ! chemosensory behavior GO:0007635 20 9 0,000 0,07144565 0,13729891 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,07144565 0,13718933 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,07144565 0,13707993 ! leukocyte degranulation GO:0043299 16 9 0,000 0,07144565 0,1369707 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,07144565 0,13686165 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,07144565 0,13675277 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,07144565 0,13664406 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,07144565 0,13653553 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,07144565 0,13642717 ! protein targeting to ER GO:0045047 22 9 0,000 0,07144565 0,13631898 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,07144565 0,13621096 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,07144565 0,13610311 ! T cell selection GO:0045058 23 9 0,000 0,07144565 0,13599544 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,07144565 0,13588793 ! endosome organization GO:0007032 17 9 0,000 0,07144565 0,13578059 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,07144565 0,13567343 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,07144565 0,13556643 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,07144565 0,1354596 ! mannose metabolic process GO:0006013 13 9 0,000 0,07144565 0,13535294 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,07144565 0,13524645 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,07144565 0,13514012 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,07144565 0,13503396 ! receptor clustering GO:0043113 18 9 0,000 0,07144565 0,13492797 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,07144565 0,13482214 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,07144565 0,13471648 ! ruffle organization GO:0031529 15 9 0,000 0,07144565 0,13461099 ! retinol metabolic process GO:0042572 18 9 0,000 0,07144565 0,13450566 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,07144565 0,13440049 ! behavioral fear response GO:0001662 22 9 0,000 0,07144565 0,13429549 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,07144565 0,13419066 GO:0007351|tripartite regional subdivision, ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,07144565 0,13408598 GO:0030204|chondroitin sulfate metabolic process, ! oligodendrocyte development GO:0014003 10 9 0,000 0,07144565 0,13398147 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,07144565 0,13387713 ! segment specification GO:0007379 13 9 0,000 0,07144565 0,13377294 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,07144565 0,13366892 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,07144565 0,13356506 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,07144565 0,13346136 ! response to amine stimulus GO:0014075 13 9 0,000 0,07144565 0,13335782 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,07144565 0,13325444 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,07144565 0,13315123 ! erythrocyte development GO:0048821 15 9 0,000 0,07144565 0,13304817 ! gas homeostasis GO:0033483 16 9 0,000 0,07144565 0,13294527 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,07144565 0,13284253 ! renal water homeostasis GO:0003091 14 9 0,000 0,07144565 0,13273995 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,07144565 0,13263752 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,07144565 0,13253526 ! icosanoid secretion GO:0032309 15 9 0,000 0,07144565 0,13243315 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,07144565 0,1323312 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,07144565 0,13222941 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,07144565 0,13212777 ! regulation of cell division GO:0051302 15 9 0,000 0,07144565 0,13202629 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,07144565 0,13192497 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,07144565 0,1318238 ! sterol catabolic process GO:0016127 11 9 0,000 0,07144565 0,13172278 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,07144565 0,13162192 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,07144565 0,13152122 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,07144565 0,13142067 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,07144565 0,13132027 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,07144565 0,13122002 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,07144565 0,13111993 ! musculoskeletal movement GO:0050881 14 9 0,000 0,07144565 0,13101999 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,07144565 0,13092021 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,07144565 0,13082057 ! purine base metabolic process GO:0006144 21 9 0,000 0,07144565 0,13072109 ! pigment granule transport GO:0051904 17 9 0,000 0,07144565 0,13062176 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,07144565 0,13052258 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,07144565 0,13042354 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,07144565 0,13032466 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,07144565 0,13022593 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,07144565 0,13012735 ! mitochondrion localization GO:0051646 15 9 0,000 0,07144565 0,13002892 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,07260218 0,13203389 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,07494764 0,13619639 ! regulation of protein catabolic process GO:0042176 116 55 1,000 0,07494764 0,1360936 ! gastrulation GO:0007369 112 55 1,000 0,07494764 0,13599096 ! heart morphogenesis GO:0003007 97 55 1,000 0,07494764 0,13588848 ! RNA elongation GO:0006354 79 55 1,000 0,07494764 0,13578616 ! regulation of actin filament length GO:0030832 105 56 1,000 0,07731707 0,13997356 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,07731707 0,13986832 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,07731707 0,13976323 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,07906332 0,14281258 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,07906332 0,14270544 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,07906332 0,14259847 ! synapsis GO:0007129 13 10 0,000 0,07906332 0,14249165 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,07906332 0,142385 ! N-glycan processing GO:0006491 20 10 0,000 0,07906332 0,1422785 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,07906332 0,14217216 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,07906332 0,14206599 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,07906332 0,14195997 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,07906332 0,14185411 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,07906332 0,1417484 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,07906332 0,14164286 ! androgen metabolic process GO:0008209 17 10 0,000 0,07906332 0,14153747 ! phospholipid efflux GO:0033700 16 10 0,000 0,07906332 0,14143223 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,07906332 0,14132716 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,07906332 0,14122224 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,07906332 0,14111747 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,07906332 0,14101287 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,07906332 0,14090841 ! endoderm development GO:0007492 16 10 0,000 0,07906332 0,14080411 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,07906332 0,14069997 ! arginine catabolic process GO:0006527 13 10 0,000 0,07906332 0,14059598 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,07906332 0,14049214 ! proline metabolic process GO:0006560 13 10 0,000 0,07906332 0,14038845 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,07906332 0,14028492 GO:0005978|glycogen biosynthetic process, ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,07906332 0,14018154 ! V(D)J recombination GO:0033151 28 10 0,000 0,07906332 0,14007832 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,07906332 0,13997524 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,07906332 0,13987232 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,07906332 0,13976955 ! B cell proliferation GO:0042100 18 10 0,000 0,07906332 0,13966693 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,07906332 0,13956446 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,07906332 0,13946214 ! multicellular organism growth GO:0035264 18 10 0,000 0,07906332 0,13935997 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,07906332 0,13925795 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,07906332 0,13915608 ! epithelial cell development GO:0002064 20 10 0,000 0,07906332 0,13905435 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,07906332 0,13895278 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,07906332 0,13885135 ! macroautophagy GO:0016236 17 10 0,000 0,07906332 0,13875008 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,07906332 0,13864895 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,07906332 0,13854796 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,07906332 0,13844713 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,07906332 0,13834644 ! copper ion homeostasis GO:0055070 13 10 0,000 0,07906332 0,1382459 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,07906332 0,1381455 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,07906332 0,13804525 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,07906332 0,13794515 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,07906332 0,13784518 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,07906332 0,13774537 ! blastoderm segmentation GO:0007350 18 10 0,000 0,07906332 0,1376457 ! response to dsRNA GO:0043331 20 10 0,000 0,07906332 0,13754617 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,07906332 0,13744679 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,07906332 0,13734755 ! melanosome localization GO:0032400 16 10 0,000 0,07906332 0,13724845 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,07906332 0,1371495 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,07906332 0,13705069 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,07906332 0,13695202 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,07906332 0,13685349 ! mRNA cleavage GO:0006379 17 10 0,000 0,07906332 0,13675511 ! protein sumoylation GO:0016925 15 10 0,000 0,07906332 0,13665686 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,07906332 0,13655876 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,07906332 0,1364608 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,07906332 0,13636298 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,07906332 0,1362653 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,07906332 0,13616776 ! salivary gland development GO:0007431 27 10 0,000 0,07906332 0,13607035 ! prophase GO:0051324 15 10 0,000 0,07906332 0,13597309 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,07906332 0,13587597 ! apical protein localization GO:0045176 15 10 0,000 0,07906332 0,13577898 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,07906332 0,13568214 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,07906332 0,13558543 ! midbrain development GO:0030901 13 10 0,000 0,07906332 0,13548886 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,07906332 0,13539242 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,07906332 0,13529613 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,07906332 0,13519997 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,07906332 0,13510395 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,07906332 0,13500806 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,07906332 0,13491231 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,07906332 0,13481669 ! detection of calcium ion GO:0005513 23 10 0,000 0,07906332 0,13472121 ! oocyte development GO:0048599 17 10 0,000 0,07906332 0,13462587 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,07906332 0,13453066 ! blastocyst formation GO:0001825 17 10 0,000 0,07906332 0,13443559 ! cerebellar cortex development GO:0021695 15 10 0,000 0,07906332 0,13434065 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,07906332 0,13424584 ! activation of innate immune response GO:0002218 12 10 0,000 0,07906332 0,13415117 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,07906332 0,13405663 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,07906332 0,13396222 ! response to nicotine GO:0035094 20 10 0,000 0,07906332 0,13386795 ! establishment of cell polarity GO:0030010 16 10 0,000 0,07906332 0,13377381 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,07906332 0,1336798 ! muscle fiber development GO:0048747 112 57 1,000 0,07970991 0,13467841 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,07970991 0,13458389 ! maintenance of location GO:0051235 118 57 1,000 0,07970991 0,13448952 ! regulation of endocytosis GO:0030100 91 58 1,000 0,08212564 0,13846831 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,08212564 0,13837135 ! regulation of cellular component size GO:0032535 109 59 1,000 0,08456371 0,14237948 ! cytokine-mediated signaling pathway GO:0019221 97 59 1,000 0,08456371 0,14227992 ! DNA catabolic process GO:0006308 86 59 1,000 0,08456371 0,14218049 ! integrin-mediated signaling pathway GO:0007229 135 59 1,000 0,08456371 0,1420812 ! establishment of organelle localization GO:0051656 109 59 1,000 0,08456371 0,14198205 ! respiratory burst GO:0045730 17 11 0,000 0,08661875 0,14533105 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,08661875 0,14522977 ! neuron fate specification GO:0048665 17 11 0,000 0,08661875 0,14512864 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,08661875 0,14502764 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,08661875 0,14492679 ! thyroid gland development GO:0030878 26 11 0,000 0,08661875 0,14482607 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,08661875 0,1447255 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,08661875 0,14462507 ! response to pain GO:0048265 24 11 0,000 0,08661875 0,14452477 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,08661875 0,14442462 ! T cell proliferation GO:0042098 26 11 0,000 0,08661875 0,1443246 ! bone resorption GO:0045453 16 11 0,000 0,08661875 0,14422472 ! ventral spinal cord development GO:0021517 21 11 0,000 0,08661875 0,14412498 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,08661875 0,14402538 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,08661875 0,14392591 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,08661875 0,14382659 ! melanocyte differentiation GO:0030318 21 11 0,000 0,08661875 0,14372739 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,08661875 0,14362834 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,08661875 0,14352942 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,08661875 0,14343064 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,08661875 0,143332 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,08661875 0,14323349 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,08661875 0,14313511 ! UV protection GO:0009650 19 11 0,000 0,08661875 0,14303687 ! adult heart development GO:0007512 14 11 0,000 0,08661875 0,14293877 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,08661875 0,1428408 ! temperature homeostasis GO:0001659 17 11 0,000 0,08661875 0,14274296 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,08661875 0,14264526 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,08661875 0,14254769 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,08661875 0,14245025 ! regulation of organ growth GO:0046620 13 11 0,000 0,08661875 0,14235295 ! pigment granule localization GO:0051875 20 11 0,000 0,08661875 0,14225578 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,08661875 0,14215875 ! vasoconstriction GO:0042310 18 11 0,000 0,08661875 0,14206184 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,08661875 0,14196507 ! embryonic axis specification GO:0000578 18 11 0,000 0,08661875 0,14186843 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,08661875 0,14177192 ! snRNA metabolic process GO:0016073 24 11 0,000 0,08661875 0,14167554 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,08661875 0,14157929 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,08661875 0,14148318 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,08661875 0,14138719 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,08661875 0,14129134 ! zymogen activation GO:0031638 15 11 0,000 0,08661875 0,14119561 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,08661875 0,14110001 ! neuroblast proliferation GO:0007405 24 11 0,000 0,08661875 0,14100455 ! nucleosome positioning GO:0016584 15 11 0,000 0,08661875 0,14090921 ! regulation of isotype switching GO:0045191 22 11 0,000 0,08661875 0,140814 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,08661875 0,14071892 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,08661875 0,14062397 ! acid secretion GO:0046717 18 11 0,000 0,08661875 0,14052914 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,08661875 0,14043445 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,08661875 0,14033988 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,08661875 0,14024544 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,08661875 0,14015112 ! oocyte differentiation GO:0009994 18 11 0,000 0,08661875 0,14005694 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,08661875 0,13996288 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,08661875 0,13986894 ! cholesterol efflux GO:0033344 19 11 0,000 0,08661875 0,13977513 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,08661875 0,13968145 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,08661875 0,13958789 ! germ cell migration GO:0008354 25 11 0,000 0,08661875 0,13949446 ! embryonic gut development GO:0048566 15 11 0,000 0,08661875 0,13940115 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,08661875 0,13930797 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,08661875 0,13921491 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,08661875 0,13912198 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,08661875 0,13902917 ! defense response to fungus GO:0050832 13 11 0,000 0,08661875 0,13893648 ! developmental induction GO:0031128 19 11 0,000 0,08661875 0,13884392 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,08661875 0,13875148 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,08661875 0,13865916 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,08661875 0,13856697 ! sequestering of metal ion GO:0051238 14 11 0,000 0,08661875 0,1384749 ! lamellipodium assembly GO:0030032 20 11 0,000 0,08661875 0,13838295 ! nucleus localization GO:0051647 19 11 0,000 0,08661875 0,13829112 ! camera-type eye development GO:0043010 116 60 1,000 0,0870236 0,13884534 ! kidney development GO:0001822 122 60 1,000 0,0870236 0,13875333 ! regulation of protein complex assembly GO:0043254 117 61 1,000 0,08950479 0,14261492 ! viral reproductive process GO:0022415 126 62 1,000 0,09200678 0,1465045 ! regulation of homeostatic process GO:0032844 134 62 1,000 0,09200678 0,14640761 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,09411245 0,14965932 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,09411245 0,14956047 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,09411245 0,14946175 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,09411245 0,14936316 ! cartilage condensation GO:0001502 20 12 0,000 0,09411245 0,1492647 ! mating GO:0007618 17 12 0,000 0,09411245 0,14916637 ! protein complex disassembly GO:0043241 27 12 0,000 0,09411245 0,14906817 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,09411245 0,1489701 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,09411245 0,14887216 ! hippocampus development GO:0021766 26 12 0,000 0,09411245 0,14877434 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,09411245 0,14867666 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,09411245 0,1485791 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,09411245 0,14848167 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,09411245 0,14838437 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,09411245 0,1482872 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,09411245 0,14819015 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,09411245 0,14809323 ! drug transport GO:0015893 16 12 0,000 0,09411245 0,14799644 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,09411245 0,14789977 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,09411245 0,14780323 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,09411245 0,14770682 ! polyamine metabolic process GO:0006595 17 12 0,000 0,09411245 0,14761053 ! mitotic spindle organization GO:0007052 21 12 0,000 0,09411245 0,14751437 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,09411245 0,14741833 ! asymmetric protein localization GO:0008105 20 12 0,000 0,09411245 0,14732241 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,09411245 0,14722663 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,09411245 0,14713096 ! entry into host cell GO:0030260 32 12 0,000 0,09411245 0,14703542 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,09411245 0,14694001 ! monoamine transport GO:0015844 18 12 0,000 0,09411245 0,14684472 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,09411245 0,14674955 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,09411245 0,1466545 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,09411245 0,14655958 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,09411245 0,14646478 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,09411245 0,1463701 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,09411245 0,14627555 ! protein homotetramerization GO:0051289 21 12 0,000 0,09411245 0,14618112 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,09411245 0,14608681 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,09411245 0,14599262 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,09411245 0,14589855 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,09411245 0,1458046 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,09411245 0,14571078 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,09411245 0,14561707 ! cranial nerve development GO:0021545 20 12 0,000 0,09411245 0,14552349 ! fucose catabolic process GO:0019317 22 12 0,000 0,09411245 0,14543003 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,09411245 0,14533668 ! histone methylation GO:0016571 26 12 0,000 0,09411245 0,14524346 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,09411245 0,14515035 ! autonomic nervous system development GO:0048483 24 12 0,000 0,09411245 0,14505737 ! gland morphogenesis GO:0022612 29 12 0,000 0,09411245 0,1449645 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,09411245 0,14487175 ! T cell homeostasis GO:0043029 25 12 0,000 0,09411245 0,14477912 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,09411245 0,14468661 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,09411245 0,14459422 ! spleen development GO:0048536 22 12 0,000 0,09411245 0,14450195 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,09411245 0,14440979 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,09411245 0,14431775 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,09411245 0,14422583 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,09411245 0,14413402 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,09411245 0,14404234 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,09411245 0,14395076 ! response to cold GO:0009409 17 12 0,000 0,09411245 0,14385931 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,09411245 0,14376797 ! regulation of lipid metabolic process GO:0019216 115 63 1,000 0,09452905 0,14431275 ! cellular amino acid catabolic process GO:0009063 101 63 1,000 0,09452905 0,14422123 ! regulation of cytokine biosynthetic process GO:0042035 95 65 1,000 0,09963246 0,15191109 ! germ cell development GO:0007281 118 65 1,000 0,09963246 0,15181489 ! cGMP metabolic process GO:0046068 18 13 0,000 0,10154491 0,15463104 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,10154491 0,15453324 ! regulation of chemokine production GO:0032642 18 13 0,000 0,10154491 0,15443556 ! peroxisomal transport GO:0043574 24 13 0,000 0,10154491 0,154338 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,10154491 0,15424056 ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,10154491 0,15414325 ! organelle fusion GO:0048284 32 13 0,000 0,10154491 0,15404606 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,10154491 0,15394899 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,10154491 0,15385205 ! endocrine pancreas development GO:0031018 22 13 0,000 0,10154491 0,15375522 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,10154491 0,15365852 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,10154491 0,15356194 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,10154491 0,15346548 ! methionine metabolic process GO:0006555 27 13 0,000 0,10154491 0,15336915 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,10154491 0,15327293 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,10154491 0,15317683 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,10154491 0,15308086 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,10154491 0,152985 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,10154491 0,15288927 ! cytokine metabolic process GO:0042107 22 13 0,000 0,10154491 0,15279365 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,10154491 0,15269816 ! exocrine system development GO:0035272 32 13 0,000 0,10154491 0,15260278 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,10154491 0,15250752 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,10154491 0,15241238 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,10154491 0,15231736 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,10154491 0,15222246 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,10154491 0,15212768 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,10154491 0,15203301 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,10154491 0,15193846 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,10154491 0,15184403 ! ribosome assembly GO:0042255 17 13 0,000 0,10154491 0,15174972 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,10154491 0,15165553 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,10154491 0,15156145 ! chromatin silencing GO:0006342 26 13 0,000 0,10154491 0,15146748 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,10154491 0,15137364 ! regulation of epidermis development GO:0045682 19 13 0,000 0,10154491 0,15127991 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,10154491 0,15118629 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,10154491 0,1510928 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,10154491 0,15099941 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,10154491 0,15090615 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,10154491 0,15081299 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,10154491 0,15071996 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,10154491 0,15062704 ! embryonic placenta development GO:0001892 23 13 0,000 0,10154491 0,15053423 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,10154491 0,15044153 ! insulin secretion GO:0030073 23 13 0,000 0,10154491 0,15034895 ! actin filament polymerization GO:0030041 24 13 0,000 0,10154491 0,15025649 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,10154491 0,15016414 ! acrosome reaction GO:0007340 18 13 0,000 0,10154491 0,1500719 ! actin filament organization GO:0007015 148 66 1,000 0,10221263 0,15096599 ! secondary metabolic process GO:0019748 116 66 1,000 0,10221263 0,15087337 ! regulation of cellular response to stress GO:0080135 128 67 1,000 0,10481114 0,1546141 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 1,000 0,10481114 0,15451936 ! homeostasis of number of cells GO:0048872 114 67 1,000 0,10481114 0,15442474 ! adaptive immune response GO:0002250 119 67 1,000 0,10481114 0,15433023 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! amino acid transport GO:0006865 125 68 1,000 0,10742751 0,15808599 ! viral reproduction GO:0016032 134 68 1,000 0,10742751 0,15798936 ! regulation of lipase activity GO:0060191 130 68 1,000 0,10742751 0,15789284 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 0,10742751 0,15779645 ! rRNA transcription GO:0009303 25 14 0,000 0,10891663 0,15988616 ! lactation GO:0007595 26 14 0,000 0,10891663 0,15978867 ! reproductive cellular process GO:0048610 20 14 0,000 0,10891663 0,1596913 ! tRNA modification GO:0006400 20 14 0,000 0,10891663 0,15959404 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,10891663 0,15949691 ! regulation of S phase GO:0033261 23 14 0,000 0,10891663 0,15939989 ! water transport GO:0006833 21 14 0,000 0,10891663 0,15930299 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,10891663 0,15920621 ! non-recombinational repair GO:0000726 25 14 0,000 0,10891663 0,15910955 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,10891663 0,159013 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,10891663 0,15891657 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,10891663 0,15882026 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,10891663 0,15872406 ! RNA polyadenylation GO:0043631 30 14 0,000 0,10891663 0,15862798 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,10891663 0,15853202 ! palate development GO:0060021 31 14 0,000 0,10891663 0,15843617 ! regulated secretory pathway GO:0045055 23 14 0,000 0,10891663 0,15834044 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,10891663 0,15824482 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,10891663 0,15814932 ! arginine metabolic process GO:0006525 17 14 0,000 0,10891663 0,15805393 ! regulation of heart rate GO:0002027 24 14 0,000 0,10891663 0,15795866 ! organic alcohol transport GO:0015850 29 14 0,000 0,10891663 0,15786351 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,10891663 0,15776847 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,10891663 0,15767354 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,10891663 0,15757873 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,10891663 0,15748403 ! neutral amino acid transport GO:0015804 26 14 0,000 0,10891663 0,15738944 ! L-amino acid transport GO:0015807 30 14 0,000 0,10891663 0,15729497 ! bone mineralization GO:0030282 17 14 0,000 0,10891663 0,15720061 ! stem cell development GO:0048864 43 14 0,000 0,10891663 0,15710637 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,10891663 0,15701224 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,10891663 0,15691822 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,10891663 0,15682431 ! cerebellum development GO:0021549 21 14 0,000 0,10891663 0,15673052 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,10891663 0,15663683 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,10891663 0,15654326 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,10891663 0,1564498 ! cofactor transport GO:0051181 26 14 0,000 0,10891663 0,15635646 ! NADP metabolic process GO:0006739 24 14 0,000 0,10891663 0,15626322 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,10891663 0,1561701 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,10891663 0,15607708 ! intestinal absorption GO:0050892 25 14 0,000 0,10891663 0,15598418 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,10891663 0,15589139 ! oxygen transport GO:0015671 21 14 0,000 0,10891663 0,1557987 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,10891663 0,15570613 ! male genitalia development GO:0030539 24 14 0,000 0,10891663 0,15561367 ! regulation of axon extension GO:0030516 37 14 0,000 0,10891663 0,15552132 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,10891663 0,15542908 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 0,11006128 0,15696944 ! antigen processing and presentation GO:0019882 104 69 1,000 0,11006128 0,15687644 ! amine catabolic process GO:0009310 117 71 1,000 0,11537919 0,16435899 ! B cell activation GO:0042113 160 71 1,000 0,11537919 0,16426174 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,11622812 0,16537247 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,11622812 0,16527473 ! superoxide anion generation GO:0042554 20 15 0,000 0,11622812 0,16517711 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,11622812 0,1650796 ! copper ion transport GO:0006825 20 15 0,000 0,11622812 0,16498221 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,11622812 0,16488494 ! sulfate transport GO:0008272 23 15 0,000 0,11622812 0,16478777 ! response to cAMP GO:0051591 22 15 0,000 0,11622812 0,16469072 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,11622812 0,16459379 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,11622812 0,16449697 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,11622812 0,16440027 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,11622812 0,16430367 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,11622812 0,16420719 ! response to hexose stimulus GO:0009746 22 15 0,000 0,11622812 0,16411083 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,11622812 0,16401458 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,11622812 0,16391844 ! vesicle coating GO:0006901 33 15 0,000 0,11622812 0,16382241 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,11622812 0,16372649 ! regulation of exocytosis GO:0017157 22 15 0,000 0,11622812 0,16363069 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,11622812 0,163535 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,11622812 0,16343942 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,11622812 0,16334395 ! regulation of vasodilation GO:0042312 26 15 0,000 0,11622812 0,1632486 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,11622812 0,16315336 ! histone deacetylation GO:0016575 20 15 0,000 0,11622812 0,16305822 ! mRNA splice site selection GO:0006376 38 15 0,000 0,11622812 0,1629632 ! tissue regeneration GO:0042246 26 15 0,000 0,11622812 0,16286829 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,11622812 0,16277349 ! water homeostasis GO:0030104 27 15 0,000 0,11622812 0,1626788 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,11622812 0,16258422 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,11622812 0,16248974 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,11622812 0,16239538 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,11622812 0,16230113 ! dopamine metabolic process GO:0042417 35 15 0,000 0,11622812 0,16220699 ! heme biosynthetic process GO:0006783 29 15 0,000 0,11622812 0,16211296 ! cell killing GO:0001906 29 15 0,000 0,11622812 0,16201903 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,11622812 0,16192522 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,11622812 0,16183151 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,11622812 0,16173791 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,11622812 0,16164442 ! peptide hormone processing GO:0016486 23 15 0,000 0,11622812 0,16155104 ! acute inflammatory response GO:0002526 113 72 1,000 0,11806243 0,1640059 ! carbohydrate transport GO:0008643 110 72 1,000 0,11806243 0,16391126 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 0,11806243 0,16381673 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 1,000 0,11806243 0,16372232 ! transition metal ion transport GO:0000041 126 74 1,000 0,1234753 0,17112994 ! regulation of actin cytoskeleton organization GO:0032956 149 74 1,000 0,1234753 0,17103142 ! organelle localization GO:0051640 136 74 1,000 0,1234753 0,17093301 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,12347985 0,17084101 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,12347985 0,17074283 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,12347985 0,17064476 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,12347985 0,1705468 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,12347985 0,17044895 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,12347985 0,17035122 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,12347985 0,17025359 ! startle response GO:0001964 28 16 0,000 0,12347985 0,17015608 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,12347985 0,17005868 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,12347985 0,1699614 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,12347985 0,16986422 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,12347985 0,16976715 ! protein polyubiquitination GO:0000209 34 16 0,000 0,12347985 0,1696702 ! glutamate metabolic process GO:0006536 22 16 0,000 0,12347985 0,16957336 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,12347985 0,16947662 ! response to osmotic stress GO:0006970 25 16 0,000 0,12347985 0,16938 ! lysosomal transport GO:0007041 26 16 0,000 0,12347985 0,16928349 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,12347985 0,16918708 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,12347985 0,16909079 ! intermediate filament-based process GO:0045103 32 16 0,000 0,12347985 0,16899461 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,12347985 0,16889853 ! negative regulation of immune response GO:0050777 35 16 0,000 0,12347985 0,16880257 ! axon cargo transport GO:0008088 43 16 0,000 0,12347985 0,16870671 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,12347985 0,16861096 ! neuron recognition GO:0008038 35 16 0,000 0,12347985 0,16851533 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,12347985 0,1684198 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,12347985 0,16832437 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,12347985 0,16822906 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,12347985 0,16813385 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,12347985 0,16803876 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,12347985 0,16794376 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,12347985 0,16784888 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,12347985 0,1677541 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,12347985 0,16765944 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,12347985 0,16756487 ! defense response to virus GO:0051607 37 16 0,000 0,12347985 0,16747042 ! regulation of vesicle-mediated transport GO:0060627 119 75 1,000 0,12620406 0,17106871 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,13067232 0,17702567 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,13067232 0,17692605 ! metencephalon development GO:0022037 30 17 0,000 0,13067232 0,17682655 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,13067232 0,17672715 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,13067232 0,17662786 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,13067232 0,17652869 ! signal complex assembly GO:0007172 41 17 0,000 0,13067232 0,17642963 ! gene silencing by RNA GO:0031047 36 17 0,000 0,13067232 0,17633068 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,13067232 0,17623184 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,13067232 0,17613311 ! adult walking behavior GO:0007628 33 17 0,000 0,13067232 0,17603449 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,13067232 0,17593598 ! heart looping GO:0001947 30 17 0,000 0,13067232 0,17583758 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,13067232 0,17573929 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,13067232 0,17564112 ! myoblast differentiation GO:0045445 45 17 0,000 0,13067232 0,17554305 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,13067232 0,17544509 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,13067232 0,17534724 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,13067232 0,1752495 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,13067232 0,17515186 ! NAD metabolic process GO:0019674 29 17 0,000 0,13067232 0,17505434 ! membrane budding GO:0006900 37 17 0,000 0,13067232 0,17495693 ! DNA integration GO:0015074 29 17 0,000 0,13067232 0,17485962 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,13067232 0,17476242 ! regulation of protein binding GO:0043393 33 17 0,000 0,13067232 0,17466533 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,13067232 0,17456835 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,13067232 0,17447147 ! genitalia development GO:0048806 30 17 0,000 0,13067232 0,17437471 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,13067232 0,17427805 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,13067232 0,17418149 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,13067232 0,17408505 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,13067232 0,17398871 ! steroid catabolic process GO:0006706 31 17 0,000 0,13067232 0,17389248 ! gas transport GO:0015669 25 17 0,000 0,13067232 0,17379635 ! organic cation transport GO:0015695 31 17 0,000 0,13067232 0,17370033 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,13067232 0,17360442 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,13067232 0,17350861 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,13067232 0,17341291 ! regulation of actin filament-based process GO:0032970 152 77 1,000 0,13170413 0,17468585 ! positive regulation of ligase activity GO:0051351 124 77 1,000 0,13170413 0,1745896 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,13170413 0,17449346 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 1,000 0,13447461 0,17806599 ! response to steroid hormone stimulus GO:0048545 137 78 1,000 0,13447461 0,17796804 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 1,000 0,13725818 0,18155205 ! regulation of synaptic transmission GO:0050804 134 79 1,000 0,13725818 0,18145229 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,137806 0,18207647 ! neuron maturation GO:0042551 42 18 0,000 0,137806 0,18197653 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,137806 0,18187671 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,137806 0,181777 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,137806 0,18167739 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,137806 0,1815779 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,137806 0,18147851 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,137806 0,18137924 ! patterning of blood vessels GO:0001569 39 18 0,000 0,137806 0,18128007 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,137806 0,18118101 GO:0042744|hydrogen peroxide catabolic process, ! epidermis morphogenesis GO:0048730 40 18 0,000 0,137806 0,18108206 ! glutamine metabolic process GO:0006541 29 18 0,000 0,137806 0,18098321 ! response to fungus GO:0009620 21 18 0,000 0,137806 0,18088448 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,137806 0,18078585 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,137806 0,18068733 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,137806 0,18058891 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,137806 0,18049061 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,137806 0,18039241 ! vitamin transport GO:0051180 27 18 0,000 0,137806 0,18029431 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,137806 0,18019633 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,137806 0,18009845 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,137806 0,18000068 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,137806 0,17990301 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,137806 0,17980545 ! nerve development GO:0021675 28 18 0,000 0,137806 0,17970799 ! inorganic anion transport GO:0015698 138 80 1,000 0,14005444 0,18254116 ! regulation of neuron differentiation GO:0045664 167 81 1,000 0,142863 0,18610091 ! protein secretion GO:0009306 39 19 0,000 0,14488139 0,18862804 ! positive regulation of translation GO:0045727 30 19 0,000 0,14488139 0,18852602 ! negative regulation of defense response GO:0031348 25 19 0,000 0,14488139 0,18842412 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,14488139 0,18832232 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,14488139 0,18822063 ! skin development GO:0043588 36 19 0,000 0,14488139 0,18811906 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,14488139 0,18801759 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,14488139 0,18791623 ! bile acid metabolic process GO:0008206 29 19 0,000 0,14488139 0,18781499 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,14488139 0,18771385 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,14488139 0,18761282 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,14488139 0,1875119 GO:0030968|endoplasmic reticulum unfolded protein response, ! heme metabolic process GO:0042168 36 19 0,000 0,14488139 0,18741108 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,14488139 0,18731038 ! protein export from nucleus GO:0006611 36 19 0,000 0,14488139 0,18720978 ! heart process GO:0003015 30 19 0,000 0,14488139 0,18710929 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,14488139 0,18700891 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,14488139 0,18690864 ! visual learning GO:0008542 36 19 0,000 0,14488139 0,18680847 ! cellular pigmentation GO:0033059 36 19 0,000 0,14488139 0,18670842 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,14488139 0,18660847 ! cell-cell junction organization GO:0045216 35 19 0,000 0,14488139 0,18650862 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,14488139 0,18640888 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,14488139 0,18630925 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,14488139 0,18620973 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,14488139 0,18611031 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,14488139 0,186011 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,14488139 0,18591179 ! cilium assembly GO:0042384 37 19 0,000 0,14488139 0,18581269 ! peptide hormone secretion GO:0030072 31 19 0,000 0,14488139 0,1857137 ! regulation of transmission of nerve impulse GO:0051969 141 84 1,000 0,15135864 0,19391314 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,15189894 0,19450178 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,15189894 0,19439832 ! positive regulation of ossification GO:0045778 47 20 0,000 0,15189894 0,19429497 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,15189894 0,19419173 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,15189894 0,19408861 ! cAMP metabolic process GO:0046058 36 20 0,000 0,15189894 0,19398559 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,15189894 0,19388268 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,15189894 0,19377988 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,15189894 0,19367718 ! response to alkaloid GO:0043279 38 20 0,000 0,15189894 0,1935746 ! retinoid metabolic process GO:0001523 32 20 0,000 0,15189894 0,19347213 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,15189894 0,19336976 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,15189894 0,1932675 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,15189894 0,19316535 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,15189894 0,19306331 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,15189894 0,19296138 ! body fluid secretion GO:0007589 31 20 0,000 0,15189894 0,19285955 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,15189894 0,19275783 ! peptide secretion GO:0002790 35 20 0,000 0,15189894 0,19265622 ! stem cell differentiation GO:0048863 53 20 0,000 0,15189894 0,19255471 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,15189894 0,19245331 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,15189894 0,19235202 ! sensory perception of pain GO:0019233 30 20 0,000 0,15189894 0,19225084 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,15189894 0,19214976 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,15189894 0,19204879 GO:0006626|protein targeting to mitochondrion, ! detection of chemical stimulus GO:0009593 37 20 0,000 0,15189894 0,19194792 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,15189894 0,19184716 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,15189894 0,19174651 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,15189894 0,19164596 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,15189894 0,19154552 ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,15189894 0,19144518 ! actin filament-based movement GO:0030048 43 20 0,000 0,15189894 0,19134495 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,15189894 0,19124482 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,15189894 0,19114479 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,15189894 0,19104487 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,15421257 0,19385342 GO:0002696|positive regulation of leukocyte activation, ! tube morphogenesis GO:0035239 176 86 1,000 0,15707693 0,19735096 ! amine transport GO:0015837 155 86 1,000 0,15707693 0,19724796 ! regulation of cell killing GO:0031341 42 21 0,000 0,15885913 0,19938188 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,15885913 0,19927793 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,15885913 0,19917409 ! hormone secretion GO:0046879 38 21 0,000 0,15885913 0,19907035 ! glycerol metabolic process GO:0006071 34 21 0,000 0,15885913 0,19896672 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,15885913 0,1988632 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,15885913 0,19875979 ! axis specification GO:0009798 38 21 0,000 0,15885913 0,19865648 ! ovarian follicle development GO:0001541 35 21 0,000 0,15885913 0,19855328 ! smooth muscle contraction GO:0006939 46 21 0,000 0,15885913 0,19845019 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,15885913 0,19834721 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,15885913 0,19824433 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,15885913 0,19814156 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,15885913 0,1980389 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,15885913 0,19793634 ! cytolysis GO:0019835 24 21 0,000 0,15885913 0,19783389 ! vasodilation GO:0042311 39 21 0,000 0,15885913 0,19773154 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,15885913 0,1976293 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,15885913 0,19752717 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,15885913 0,19742514 ! oogenesis GO:0048477 36 21 0,000 0,15885913 0,19732322 ! DNA modification GO:0006304 34 21 0,000 0,15885913 0,1972214 ! collagen fibril organization GO:0030199 59 21 0,000 0,15885913 0,19711969 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,15885913 0,19701808 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,15885913 0,19691658 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,15885913 0,19681518 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,15885913 0,19671388 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,15885913 0,19661269 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,15885913 0,19651161 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,15885913 0,19641062 ! collagen catabolic process GO:0030574 28 21 0,000 0,15885913 0,19630974 ! sperm-egg recognition GO:0035036 21 21 0,000 0,15885913 0,19620897 ! gut development GO:0048565 39 21 0,000 0,15885913 0,1961083 ! nitrogen compound catabolic process GO:0044270 143 87 1,000 0,15995134 0,19735534 ! regulation of neurological system process GO:0031644 148 88 1,000 0,16283545 0,20081091 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,16576243 0,20431579 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,16576243 0,20421117 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,16576243 0,20410666 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,16576243 0,20400226 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,16576243 0,20389796 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,16576243 0,20379378 ! regeneration GO:0031099 41 22 0,000 0,16576243 0,20368969 ! keratinization GO:0031424 28 22 0,000 0,16576243 0,20358572 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,16576243 0,20348185 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,16576243 0,20337808 ! sensory perception of taste GO:0050909 28 22 0,000 0,16576243 0,20327442 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,16576243 0,20317087 ! vacuolar transport GO:0007034 36 22 0,000 0,16576243 0,20306742 ! lysosome organization GO:0007040 41 22 0,000 0,16576243 0,20296408 ! central nervous system neuron development GO:0021954 46 22 0,000 0,16576243 0,20286084 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,16576243 0,20275771 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,16576243 0,20265468 ! fucose metabolic process GO:0006004 39 22 0,000 0,16576243 0,20255176 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,16576243 0,20244894 ! ureteric bud development GO:0001657 43 22 0,000 0,16576243 0,20234623 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,16576243 0,20224362 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,16576243 0,20214111 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,16576243 0,20203871 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,16576243 0,20193641 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,16576243 0,20183422 ! sarcomere organization GO:0045214 30 22 0,000 0,16576243 0,20173213 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,16576243 0,20163014 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,16576243 0,20152826 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,16576243 0,20142647 ! protein stabilization GO:0050821 39 22 0,000 0,16576243 0,20132479 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,17260931 0,20953481 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,17260931 0,20942915 ! gluconeogenesis GO:0006094 33 23 0,000 0,17260931 0,20932359 ! viral genome replication GO:0019079 41 23 0,000 0,17260931 0,20921813 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,17260931 0,20911279 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,17260931 0,20900755 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,17260931 0,20890241 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,17260931 0,20879738 GO:0006044|N-acetylglucosamine metabolic process, ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,17260931 0,20869246 ! visual behavior GO:0007632 42 23 0,000 0,17260931 0,20858764 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,17260931 0,20848293 ! response to ethanol GO:0045471 46 23 0,000 0,17260931 0,20837832 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,17260931 0,20827382 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,17260931 0,20816942 ! peroxisome organization GO:0007031 37 23 0,000 0,17260931 0,20806513 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,17260931 0,20796094 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,17260931 0,20785686 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,17260931 0,20775288 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,17260931 0,207649 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,17260931 0,20754523 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,17260931 0,20744156 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,17260931 0,20733799 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,17260931 0,20723453 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,17260931 0,20713117 ! fatty acid transport GO:0015908 44 23 0,000 0,17260931 0,20702791 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,17260931 0,20692476 ! hormone transport GO:0009914 40 23 0,000 0,17260931 0,20682171 ! cell-cell recognition GO:0009988 25 23 0,000 0,17260931 0,20671876 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,17260931 0,20661592 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,17260931 0,20651318 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,17260931 0,20641054 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,17260931 0,206308 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,17260931 0,20620556 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 0,1773894 0,21181087 GO:0010498|proteasomal protein catabolic process, ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,17940021 0,21410561 GO:0016444|somatic cell DNA recombination, ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,17940021 0,21399946 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,17940021 0,21389342 ! vesicle docking GO:0048278 47 24 0,000 0,17940021 0,21378748 ! spinal cord development GO:0021510 47 24 0,000 0,17940021 0,21368164 ! vacuole organization GO:0007033 43 24 0,000 0,17940021 0,21357591 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,17940021 0,21347028 ! digestive system process GO:0022600 39 24 0,000 0,17940021 0,21336476 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,17940021 0,21325935 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,17940021 0,21315403 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,17940021 0,21304882 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,17940021 0,21294372 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,17940021 0,21283872 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,17940021 0,21273382 ! membrane depolarization GO:0051899 39 24 0,000 0,17940021 0,21262902 ! pentose metabolic process GO:0019321 35 24 0,000 0,17940021 0,21252433 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,17940021 0,21241974 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,17940021 0,21231526 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,17940021 0,21221087 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,17940021 0,21210659 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,17940021 0,21200241 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,17940021 0,21189834 ! regulation of amine transport GO:0051952 40 24 0,000 0,17940021 0,21179436 ! transcription initiation GO:0006352 153 94 1,000 0,18032453 0,21278117 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,18613561 0,21953052 ! phototransduction GO:0007602 33 25 0,000 0,18613561 0,21942296 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,18613561 0,21931551 GO:0006479|protein amino acid methylation, ! sperm motility GO:0030317 31 25 0,000 0,18613561 0,21920816 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,18613561 0,21910091 ! receptor metabolic process GO:0043112 46 25 0,000 0,18613561 0,21899377 ! chromosome condensation GO:0030261 45 25 0,000 0,18613561 0,21888674 ! osteoblast differentiation GO:0001649 60 25 0,000 0,18613561 0,21877981 ! neural crest cell development GO:0014032 54 25 0,000 0,18613561 0,21867298 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,18613561 0,21856626 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,18613561 0,21845964 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,18613561 0,21835313 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,18613561 0,21824672 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,18613561 0,21814041 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,18613561 0,21803421 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,18613561 0,21792811 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,18613561 0,21782211 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,18613561 0,21771622 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,18613561 0,21761043 ! telomere organization GO:0032200 43 25 0,000 0,18613561 0,21750474 GO:0000723|telomere maintenance, ! liver development GO:0001889 53 25 0,000 0,18613561 0,21739916 ! response to virus GO:0009615 160 98 1,000 0,1921354 0,2242978 ! carboxylic acid catabolic process GO:0046395 156 98 1,000 0,1921354 0,22418902 GO:0016054|organic acid catabolic process, ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,19281594 0,22487404 ! embryonic pattern specification GO:0009880 44 26 0,000 0,19281594 0,22476509 ! initiation of viral infection GO:0019059 57 26 0,000 0,19281594 0,22465624 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,19281594 0,2245475 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,19281594 0,22443887 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,19281594 0,22433034 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,19281594 0,22422192 ! molting cycle process GO:0022404 50 26 0,000 0,19281594 0,2241136 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,19281594 0,22400538 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,19281594 0,22389727 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,19281594 0,22378926 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,19281594 0,22368136 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,19281594 0,22357356 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,19281594 0,22346587 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,19281594 0,22335828 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,19281594 0,22325079 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,19281594 0,22314341 ! blastocyst development GO:0001824 49 26 0,000 0,19281594 0,22303613 ! leukocyte proliferation GO:0070661 52 26 0,000 0,19281594 0,22292895 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,19281594 0,22282187 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,19281594 0,2227149 ! neuron fate commitment GO:0048663 48 27 0,000 0,19944165 0,23025749 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,19944165 0,23014706 ! iron ion transport GO:0006826 59 27 0,000 0,19944165 0,23003673 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,19944165 0,22992651 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,19944165 0,22981639 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,19944165 0,22970638 ! fat cell differentiation GO:0045444 50 27 0,000 0,19944165 0,22959647 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,19944165 0,22948667 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,19944165 0,22937697 ! autophagy GO:0006914 41 27 0,000 0,19944165 0,22926738 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,19944165 0,22915789 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,19944165 0,22904851 ! glutathione metabolic process GO:0006749 39 27 0,000 0,19944165 0,22893923 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,19944165 0,22883005 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,19944165 0,22872098 ! circadian rhythm GO:0007623 50 28 0,000 0,2060132 0,23614472 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,2060132 0,23603227 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,2060132 0,23591993 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,2060132 0,23580769 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,2060132 0,23569556 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,2060132 0,23558354 ! synaptogenesis GO:0007416 42 28 0,000 0,2060132 0,23547162 ! lipid oxidation GO:0034440 43 28 0,000 0,2060132 0,23535981 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,2060132 0,23524811 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,2060132 0,23513651 ! translational initiation GO:0006413 65 29 0,000 0,21253102 0,24246071 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,21253102 0,2423458 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,21253102 0,242231 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,21253102 0,24211631 ! catechol metabolic process GO:0009712 54 29 0,000 0,21253102 0,24200173 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,21253102 0,24188725 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,21253102 0,24177288 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,21253102 0,24165862 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,21253102 0,24154447 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,21253102 0,24143043 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,21253102 0,24131649 ! cell fate determination GO:0001709 60 29 0,000 0,21253102 0,24120266 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,21253102 0,24108894 ! detection of light stimulus GO:0009583 38 29 0,000 0,21253102 0,24097533 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,21253102 0,24086182 ! tissue homeostasis GO:0001894 48 29 0,000 0,21253102 0,24074842 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,21253102 0,24063513 ! phenol metabolic process GO:0018958 55 30 0,000 0,21899556 0,24783787 ! membrane docking GO:0022406 61 30 0,000 0,21899556 0,24772135 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,21899556 0,24760494 ! regulation of innate immune response GO:0045088 51 30 0,000 0,21899556 0,24748864 ! myofibril assembly GO:0030239 47 30 0,000 0,21899556 0,24737245 GO:0055002|striated muscle cell development, ! determination of left/right symmetry GO:0007368 47 30 0,000 0,21899556 0,24725636 ! phospholipid transport GO:0015914 51 30 0,000 0,21899556 0,24714039 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,21899556 0,24702452 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,21899556 0,24690877 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,21899556 0,24679312 ! eye morphogenesis GO:0048592 60 30 0,000 0,21899556 0,24667758 ! response to heat GO:0009408 50 30 0,000 0,21899556 0,24656215 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,22540723 0,25366221 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,22540723 0,25354362 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,22540723 0,25342514 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,22540723 0,25330677 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,22540723 0,25318852 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,22540723 0,25307037 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,22540723 0,25295233 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,22540723 0,25283441 ! ovulation cycle process GO:0022602 49 31 0,000 0,22540723 0,25271659 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,22540723 0,25259888 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,22540723 0,25248129 ! peptide transport GO:0015833 55 31 0,000 0,22540723 0,2523638 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,22540723 0,25224642 ! iron ion homeostasis GO:0055072 54 31 0,000 0,22540723 0,25212915 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,22540723 0,25201199 ! natural killer cell activation GO:0030101 45 31 0,000 0,22540723 0,25189494 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,22540723 0,251778 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,22540723 0,25166116 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,22540723 0,25154444 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,23176648 0,25852117 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,23176648 0,25840137 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,23176648 0,25828169 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,23176648 0,25816211 ! cholesterol transport GO:0030301 56 32 0,000 0,23176648 0,25804265 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,23176648 0,25792329 ! spliceosome assembly GO:0000245 67 32 0,000 0,23176648 0,25780405 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,23176648 0,25768492 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,23176648 0,25756589 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,23176648 0,25744698 ! muscle cell development GO:0055001 49 32 0,000 0,23176648 0,25732818 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,23176648 0,25720948 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,23176648 0,2570909 ! ovulation cycle GO:0042698 51 32 0,000 0,23176648 0,25697242 ! BMP signaling pathway GO:0030509 64 32 0,000 0,23176648 0,25685406 ! hindbrain development GO:0030902 61 32 0,000 0,23176648 0,2567358 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,23176648 0,25661765 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,23176648 0,25649961 ! gene silencing GO:0016458 65 32 0,000 0,23176648 0,25638168 ! protein targeting to membrane GO:0006612 68 33 0,000 0,23807374 0,26323778 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,23807374 0,26311686 ! ceramide metabolic process GO:0006672 64 33 0,000 0,23807374 0,26299605 ! sterol transport GO:0015918 57 33 0,000 0,23807374 0,26287536 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,23807374 0,26275477 ! adult locomotory behavior GO:0008344 59 33 0,000 0,23807374 0,2626343 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,23807374 0,26251394 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,23807374 0,26239368 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,24432941 0,26916509 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,24432941 0,26904191 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,24432941 0,26891883 ! mismatch repair GO:0006298 46 34 0,000 0,24432941 0,26879587 ! spermatid development GO:0007286 63 34 0,000 0,24432941 0,26867302 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,24432941 0,26855028 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,24432941 0,26842766 ! placenta development GO:0001890 53 34 0,000 0,24432941 0,26830514 ! negative regulation of secretion GO:0051048 63 35 0,000 0,25053393 0,274993 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,25053393 0,2748676 ! odontogenesis GO:0042476 66 35 0,000 0,25053393 0,27474232 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,25053393 0,27461715 ! female gonad development GO:0008585 58 35 0,000 0,25053393 0,2744921 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,25053393 0,27436716 GO:0006639|acylglycerol metabolic process, ! cytokine production GO:0001816 59 35 0,000 0,25053393 0,27424233 ! vesicle localization GO:0051648 64 35 0,000 0,25053393 0,27411762 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,25668772 0,28072302 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,25668772 0,28059548 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,25668772 0,28046805 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,25668772 0,28034074 ! positive regulation of cell development GO:0010720 80 36 0,000 0,25668772 0,28021354 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,25668772 0,28008646 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,25668772 0,2799595 ! aerobic respiration GO:0009060 55 36 0,000 0,25668772 0,27983265 ! embryonic organ development GO:0048568 57 36 0,000 0,25668772 0,27970591 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,25668772 0,27957929 ! RNA export from nucleus GO:0006405 56 37 0,000 0,26279118 0,28609754 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,26279118 0,28596815 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,26279118 0,28583887 ! actomyosin structure organization GO:0031032 62 37 0,000 0,26279118 0,2857097 ! organic anion transport GO:0015711 68 37 0,000 0,26279118 0,28558066 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,26279118 0,28545172 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,26279118 0,28532291 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,26279118 0,28519421 GO:0015986|ATP synthesis coupled proton transport, ! pigment metabolic process GO:0042440 80 37 0,000 0,26279118 0,28506563 ! spermatid differentiation GO:0048515 66 37 0,000 0,26279118 0,28493717 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,26884472 0,29136955 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,26884472 0,29123836 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,26884472 0,29110729 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,26884472 0,29097634 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 67 38 0,000 0,26884472 0,2908455 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,26884472 0,29071478 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,26884472 0,29058418 ! mRNA catabolic process GO:0006402 71 39 0,000 0,27484875 0,29694032 ! learning GO:0007612 77 39 0,000 0,27484875 0,29680705 ! ear morphogenesis GO:0042471 60 39 0,000 0,27484875 0,29667389 ! organic ether metabolic process GO:0018904 55 39 0,000 0,27484875 0,29654085 ! ion transmembrane transport GO:0034220 66 39 0,000 0,27484875 0,29640793 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,27484875 0,29627514 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,27484875 0,29614246 ! RNA modification GO:0009451 57 39 0,000 0,27484875 0,29600989 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,27484875 0,29587745 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,28080368 0,3021528 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,28080368 0,30201773 ! feeding behavior GO:0007631 59 40 0,000 0,28080368 0,30188278 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,28080368 0,30174795 ! maintenance of protein location GO:0045185 91 40 0,000 0,28080368 0,30161324 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,28670991 0,30781974 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,28670991 0,30768244 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,28670991 0,30754527 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,28670991 0,30740822 ! female gamete generation GO:0007292 61 41 0,000 0,28670991 0,30727129 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,28670991 0,30713448 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,29256782 0,31327022 ! regulation of tube size GO:0035150 71 42 0,000 0,29256782 0,31313086 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,29256782 0,31299163 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,29256782 0,31285252 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,29256782 0,31271354 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,29256782 0,31257468 ! regulation of protein secretion GO:0050708 71 42 0,000 0,29256782 0,31243594 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,29256782 0,31229733 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,29837782 0,31835789 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,29837782 0,31821677 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,29837782 0,31807578 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,29837782 0,31793492 ! striated muscle contraction GO:0006941 77 43 0,000 0,29837782 0,31779417 ! phagocytosis GO:0006909 90 43 0,000 0,29837782 0,31765356 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,29837782 0,31751306 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,3041403 0,32350201 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,3041403 0,32335906 ! biopolymer methylation GO:0043414 84 44 0,000 0,3041403 0,32321623 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,3041403 0,32307353 ! developmental growth GO:0048589 82 44 0,000 0,3041403 0,32293096 ! maintenance of location in cell GO:0051651 97 44 0,000 0,3041403 0,32278851 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,30985563 0,32870928 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,30985563 0,32856441 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,30985563 0,32841967 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,30985563 0,32827506 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,30985563 0,32813057 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,30985563 0,32798621 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,30985563 0,32784198 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,31552422 0,33369287 ! response to calcium ion GO:0051592 81 47 0,000 0,32114643 0,33948959 ! endosome transport GO:0016197 108 47 0,000 0,32114643 0,3393405 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,32114643 0,33919153 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,32114643 0,3390427 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,32114643 0,338894 ! methylation GO:0032259 90 47 0,000 0,32114643 0,33874542 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,32672265 0,3444762 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,32672265 0,34432531 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,33225324 0,35000057 ! regulation of ion transport GO:0043269 77 49 0,000 0,33225324 0,3498474 ! peptide metabolic process GO:0006518 76 49 0,000 0,33225324 0,34969436 ! response to temperature stimulus GO:0009266 76 49 0,000 0,33225324 0,34954145 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,33225324 0,34938868 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,33225324 0,34923604 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,33225324 0,34908354 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,33225324 0,34893117 ! neuromuscular process GO:0050905 99 50 0,000 0,33773859 0,35453711 ! inner ear development GO:0048839 79 50 0,000 0,33773859 0,35438249 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,33773859 0,35422801 ! viral infectious cycle GO:0019058 99 51 0,000 0,34317906 0,35977726 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,34317906 0,35962057 ! excretion GO:0007588 83 51 0,000 0,34317906 0,359464 ! chromatin remodeling GO:0006338 109 51 0,000 0,34317906 0,35930758 ! vesicle organization GO:0016050 107 51 0,000 0,34317906 0,35915129 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,34857501 0,36463978 ! amino acid activation GO:0043038 92 52 0,000 0,34857501 0,36448131 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 76 53 0,000 0,35392682 0,36991656 ! RNA catabolic process GO:0006401 93 53 0,000 0,35392682 0,36975594 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,35392682 0,36959545 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,35392682 0,36943511 ! cell maturation GO:0048469 100 53 0,000 0,35392682 0,3692749 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,35923483 0,37465063 ! cell recognition GO:0008037 85 54 0,000 0,35923483 0,3744883 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,35923483 0,37432612 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,35923483 0,37416407 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,35923483 0,37400216 ! chloride transport GO:0006821 90 55 0,000 0,36449941 0,37931902 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,36449941 0,37915503 ! nuclear export GO:0051168 97 55 0,000 0,36449941 0,37899117 ! sensory perception of smell GO:0007608 80 56 0,000 0,3697209 0,38425421 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,3697209 0,3840883 ! proton transport GO:0015992 94 56 0,000 0,3697209 0,38392253 ! hydrogen transport GO:0006818 97 58 0,000 0,38003606 0,39446366 ! adult behavior GO:0030534 99 58 0,000 0,38003606 0,39429356 ! positive regulation of secretion GO:0051047 95 59 0,000 0,38513041 0,3994068 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,38513041 0,39923471 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,38513041 0,39906278 GO:0032313|regulation of Rab GTPase activity, ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,39018307 0,40412418 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,39018307 0,40395028 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,39519437 0,40896243 ! tRNA processing GO:0008033 89 61 0,000 0,39519437 0,40878661 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,39519437 0,40861094 ! ear development GO:0043583 103 62 0,000 0,40016466 0,41357224 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,40016466 0,41339466 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,40509427 0,41830764 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,40998352 0,42317476 ! cell redox homeostasis GO:0045454 102 64 0,000 0,40998352 0,42299329 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,40998352 0,42281198 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,40998352 0,42263083 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,40998352 0,42244983 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,41483276 0,42726354 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,41483276 0,42708071 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,4196423 0,43184747 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,4196423 0,43166284 ! extracellular matrix organization GO:0030198 133 66 0,000 0,4196423 0,43147836 ! developmental maturation GO:0021700 116 66 0,000 0,4196423 0,43129405 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,42441247 0,43601042 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,42441247 0,43582433 ! activation of immune response GO:0002253 105 67 0,000 0,42441247 0,4356384 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,42914359 0,44030681 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,42914359 0,44011913 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,43383597 0,44474195 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,43383597 0,44455254 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,43383597 0,44436328 ! humoral immune response GO:0006959 109 71 0,000 0,44310581 0,45366493 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,44310581 0,45347196 ! regulation of immune effector process GO:0002697 137 71 0,000 0,44310581 0,45327916 ! regulation of blood pressure GO:0008217 125 73 0,000 0,45222448 0,46241058 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,45222448 0,46221415 ! fertilization GO:0009566 90 73 0,000 0,45222448 0,46201788 ! neurotransmitter transport GO:0006836 123 74 0,000 0,45672789 0,46642076 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,45672789 0,46622287 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,46119443 0,47058261 ! rhythmic process GO:0048511 128 75 0,000 0,46119443 0,47038313 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,4656244 0,47470013 ! defense response to bacterium GO:0042742 89 76 0,000 0,4656244 0,47449907 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,47001808 0,47877371 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,47869781 0,48740878 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,48298444 0,49156538 ! response to metal ion GO:0010038 140 80 0,000 0,48298444 0,49135753 ! muscle cell differentiation GO:0042692 159 80 0,000 0,48298444 0,49114985 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,48298444 0,49094236 ! digestion GO:0007586 112 81 0,000 0,48723596 0,49505478 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,48723596 0,4948458 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,49145265 0,49891776 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,49145265 0,49870733 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,49145265 0,49849708 ! regulation of lyase activity GO:0051339 160 83 0,000 0,49563481 0,50252733 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,49978272 0,50651947 ! response to unfolded protein GO:0006986 131 85 0,000 0,50389665 0,51047383 ! nucleosome assembly GO:0006334 122 85 0,000 0,50389665 0,51025898 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,50389665 0,51004432 ! response to inorganic substance GO:0010035 153 86 0,000 0,50797688 0,51395811 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,50797688 0,51374207 ! chromatin assembly GO:0031497 124 86 0,000 0,50797688 0,51352621 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,51202369 0,51739983 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! cellular respiration GO:0045333 135 88 0,000 0,51603735 0,52123672 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,51603735 0,52101799 ! cellular defense response GO:0006968 114 89 0,000 0,52001813 0,52481695 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,52396629 0,52857983 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,52396629 0,5283583 ! sterol metabolic process GO:0016125 152 91 0,000 0,52788211 0,53208394 ! response to protein stimulus GO:0051789 149 91 0,000 0,52788211 0,53186112 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,52788211 0,53163849 ! nucleosome organization GO:0034728 138 92 0,000 0,53176585 0,53532579 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,53176585 0,5351019 ! vitamin metabolic process GO:0006766 139 92 0,000 0,53176585 0,53487819 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,53561777 0,53852752 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,53561777 0,53830257 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,53943812 0,54191571 ! female pregnancy GO:0007565 164 94 0,000 0,53943812 0,54168954 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,54322718 0,54526683 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,54698519 0,54880999 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,54698519 0,54858122 ! positive regulation of immune response GO:0050778 156 96 0,000 0,54698519 0,54835265 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,5507124 0,55185924 ! protein ubiquitination GO:0016567 217 97 0,000 0,5507124 0,55162949 ! hormone metabolic process GO:0042445 157 97 0,000 0,5507124 0,55139993 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,55440907 0,55487031 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,55807545 0,55830749 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,55807545 0,55807545