Study Desmedt-ER-neg
Study informations
165 subnetworks in total page | file
2310 genes associated page | file
Enriched GO terms page
General informations
General Index page
Study Index page
Subnetwork 6619
score
| Dataset | Score | P-val 1 | P-val 2 | P-val 3 | Fisher Score |
| IPC | 0.7534 | 3.543e-03 | 5.780e-04 | 7.718e-01 | 1.581e-06 |
| Loi | 0.2305 | 8.004e-02 | 1.130e-02 | 4.277e-01 | 3.867e-04 |
| Schmidt | 0.6741 | 0.000e+00 | 0.000e+00 | 4.422e-02 | 0.000e+00 |
| VanDeVijver | 0.7908 | 0.000e+00 | 0.000e+00 | 3.470e-03 | 0.000e+00 |
| Wang | 0.2622 | 2.588e-03 | 4.299e-02 | 3.925e-01 | 4.367e-05 |
Expression data for subnetwork 6619 in each dataset
IPC |
Loi |
Schmidt |
VanDeVijver |
Wang |
Subnetwork structure for each dataset
- IPC

Score for each gene in subnetwork 6619 in each dataset
| Gene Symbol | Links | Frequency | Frequency Rank | Subnetwork score rank | Global rank |
IPC | Loi | Schmidt | VanDeVijver | Wang |
| EP300 |  | 113 | 4 | 1 | 4 | -0.149 | 0.087 | 0.102 | 0.052 | 0.025 |
| CCNE2 |  | 11 | 148 | 412 | 407 | 0.136 | -0.178 | 0.241 | undef | -0.055 |
| SORBS1 |  | 57 | 19 | 1 | 13 | -0.043 | 0.015 | 0.314 | -0.072 | 0.200 |
| DUSP8 |  | 4 | 440 | 1 | 59 | 0.118 | 0.257 | 0.068 | 0.208 | -0.029 |
| SF3B1 |  | 18 | 86 | 296 | 280 | -0.154 | 0.126 | -0.073 | -0.131 | -0.204 |
| RET |  | 7 | 256 | 366 | 376 | 0.098 | 0.063 | -0.179 | undef | -0.159 |
| TP53 |  | 85 | 7 | 1 | 6 | -0.167 | 0.148 | -0.027 | 0.252 | 0.147 |
| TPX2 |  | 5 | 360 | 412 | 416 | 0.114 | -0.121 | -0.018 | undef | -0.056 |
| ERBB2 |  | 141 | 1 | 1 | 1 | -0.103 | 0.092 | -0.090 | 0.267 | 0.046 |
| PTP4A3 |  | 9 | 196 | 412 | 411 | 0.137 | -0.196 | 0.085 | undef | -0.004 |
| IRX4 |  | 2 | 743 | 412 | 439 | -0.012 | 0.137 | -0.018 | -0.139 | 0.125 |
| ID4 |  | 35 | 34 | 236 | 223 | -0.179 | 0.137 | 0.241 | undef | 0.036 |
| CDKN1A |  | 110 | 5 | 1 | 5 | 0.064 | 0.254 | 0.030 | undef | 0.082 |
| PRKCA |  | 63 | 15 | 1 | 10 | -0.016 | -0.088 | 0.174 | 0.095 | 0.005 |
| BARD1 |  | 69 | 12 | 141 | 132 | 0.179 | -0.165 | 0.086 | 0.245 | -0.104 |
| GRM5 |  | 15 | 111 | 179 | 191 | 0.094 | -0.019 | 0.000 | 0.093 | -0.093 |
| CCND1 |  | 26 | 52 | 1 | 24 | -0.258 | 0.074 | 0.117 | undef | 0.003 |
| CCNA2 |  | 21 | 73 | 179 | 183 | 0.176 | -0.053 | 0.188 | -0.078 | 0.246 |
| PCNA |  | 15 | 111 | 1 | 32 | 0.243 | -0.158 | 0.027 | -0.099 | 0.003 |
| SNRPD1 |  | 2 | 743 | 412 | 439 | 0.140 | -0.211 | 0.198 | -0.045 | -0.008 |
| PIN1 |  | 24 | 62 | 179 | 181 | 0.194 | 0.040 | -0.040 | 0.065 | -0.048 |
| TWIST1 |  | 50 | 20 | 1 | 14 | 0.044 | 0.194 | 0.061 | undef | 0.219 |
| ACOX2 |  | 3 | 557 | 412 | 430 | 0.013 | 0.100 | -0.021 | 0.134 | 0.047 |
| KIT |  | 39 | 29 | 1 | 18 | -0.130 | -0.091 | 0.235 | -0.046 | -0.059 |
| STRAP |  | 7 | 256 | 412 | 414 | 0.035 | -0.128 | 0.074 | 0.154 | -0.049 |
| AFG3L2 |  | 1 | 1195 | 412 | 464 | 0.013 | -0.211 | 0.098 | -0.131 | -0.010 |
| CCL15 |  | 2 | 743 | 412 | 439 | -0.190 | 0.004 | 0.141 | -0.215 | 0.007 |
| PDK1 |  | 10 | 167 | 1 | 40 | 0.183 | -0.138 | -0.041 | -0.265 | -0.126 |
| DPM1 |  | 1 | 1195 | 412 | 464 | 0.177 | -0.072 | 0.133 | -0.025 | 0.009 |
| PPARG |  | 7 | 256 | 179 | 201 | -0.119 | 0.011 | 0.105 | 0.059 | 0.039 |
| AKT2 |  | 28 | 47 | 412 | 394 | 0.110 | -0.118 | -0.003 | 0.088 | -0.092 |
| SUMO3 |  | 3 | 557 | 412 | 430 | 0.126 | 0.081 | 0.087 | 0.138 | -0.073 |
| MMP1 |  | 11 | 148 | 366 | 360 | 0.192 | 0.014 | 0.036 | 0.044 | 0.260 |
| GLO1 |  | 5 | 360 | 83 | 110 | 0.266 | -0.089 | 0.135 | 0.100 | 0.076 |
| LUC7L |  | 1 | 1195 | 412 | 464 | -0.029 | -0.025 | 0.102 | -0.018 | -0.019 |
| RCN2 |  | 3 | 557 | 412 | 430 | 0.059 | 0.051 | 0.176 | 0.008 | -0.098 |
| CDK1 |  | 63 | 15 | 83 | 79 | 0.265 | -0.195 | 0.106 | 0.088 | 0.031 |
| AHSG |  | 5 | 360 | 412 | 416 | -0.113 | -0.054 | 0.000 | 0.132 | undef |
| AGPAT2 |  | 3 | 557 | 412 | 430 | 0.167 | -0.015 | 0.123 | 0.042 | -0.076 |
| LUC7L3 |  | 16 | 104 | 296 | 281 | 0.043 | 0.237 | 0.175 | 0.135 | 0.074 |
| CLCA2 |  | 9 | 196 | 412 | 411 | -0.176 | 0.243 | -0.153 | 0.191 | -0.000 |
| CCNA1 |  | 33 | 37 | 412 | 393 | 0.174 | 0.092 | 0.078 | 0.055 | -0.098 |
| TNFRSF1A |  | 8 | 222 | 412 | 413 | 0.050 | 0.094 | -0.014 | 0.214 | -0.045 |
| ITGB1 |  | 1 | 1195 | 412 | 464 | 0.016 | 0.093 | 0.154 | undef | 0.074 |
| GSK3B |  | 79 | 8 | 179 | 169 | -0.130 | 0.292 | -0.129 | 0.291 | 0.057 |
| KLF5 |  | 76 | 9 | 1 | 7 | 0.077 | 0.117 | -0.007 | -0.110 | -0.006 |
| PSPH |  | 20 | 81 | 366 | 356 | 0.240 | -0.019 | -0.102 | 0.358 | 0.025 |
| NCOR2 |  | 32 | 40 | 318 | 290 | -0.096 | 0.211 | -0.163 | 0.158 | 0.114 |
| GYG2 |  | 2 | 743 | 412 | 439 | 0.092 | -0.015 | 0.020 | 0.189 | -0.004 |
| CX3CR1 |  | 2 | 743 | 412 | 439 | -0.213 | 0.060 | 0.113 | -0.040 | -0.050 |
| GSTT1 |  | 15 | 111 | 1 | 32 | 0.148 | 0.107 | -0.190 | 0.022 | -0.064 |
| IGF2BP2 |  | 2 | 743 | 412 | 439 | 0.210 | -0.002 | 0.098 | -0.098 | -0.122 |
| KIAA1377 |  | 18 | 86 | 141 | 136 | -0.095 | 0.116 | undef | 0.198 | undef |
| IKBKAP |  | 10 | 167 | 412 | 408 | 0.089 | 0.184 | 0.142 | 0.105 | -0.017 |
| ITGB5 |  | 4 | 440 | 412 | 419 | 0.163 | 0.208 | 0.081 | 0.278 | 0.148 |
| COPG2 |  | 4 | 440 | 412 | 419 | -0.058 | -0.232 | 0.000 | 0.086 | -0.081 |
| ADA |  | 4 | 440 | 83 | 112 | 0.208 | -0.164 | -0.042 | -0.102 | 0.219 |
| TOP2A |  | 20 | 81 | 1 | 28 | 0.193 | -0.168 | 0.054 | -0.064 | 0.071 |
| SPP1 |  | 26 | 52 | 83 | 91 | 0.130 | 0.119 | 0.184 | 0.204 | 0.153 |
| CCR1 |  | 2 | 743 | 412 | 439 | 0.162 | -0.205 | -0.049 | -0.123 | -0.109 |
| PTEN |  | 27 | 50 | 141 | 135 | 0.045 | 0.055 | 0.017 | 0.183 | -0.041 |
| MYC |  | 72 | 10 | 1 | 8 | -0.101 | -0.169 | 0.188 | undef | -0.134 |
| CCL4 |  | 1 | 1195 | 412 | 464 | 0.211 | -0.334 | -0.065 | -0.166 | 0.003 |
| BCL2 |  | 37 | 32 | 83 | 82 | -0.077 | -0.035 | 0.128 | -0.106 | 0.043 |
| BNIP3 |  | 11 | 148 | 236 | 232 | 0.193 | 0.071 | 0.102 | 0.119 | 0.285 |
| ERRFI1 |  | 10 | 167 | 412 | 408 | 0.076 | 0.215 | undef | -0.043 | undef |
| C1orf103 |  | 4 | 440 | 412 | 419 | 0.057 | 0.029 | -0.173 | 0.127 | -0.159 |
| DLX4 |  | 10 | 167 | 236 | 234 | 0.291 | 0.057 | -0.004 | undef | -0.059 |
| MYB |  | 28 | 47 | 366 | 344 | -0.028 | 0.075 | 0.002 | 0.065 | -0.012 |
| DUSP1 |  | 4 | 440 | 1 | 59 | -0.019 | 0.127 | 0.170 | -0.031 | 0.134 |
| MN1 |  | 3 | 557 | 366 | 389 | -0.166 | -0.047 | 0.150 | 0.010 | 0.011 |
| CCL7 |  | 2 | 743 | 412 | 439 | 0.204 | -0.142 | 0.011 | undef | -0.140 |
| PNP |  | 2 | 743 | 412 | 439 | 0.036 | -0.012 | 0.108 | -0.040 | 0.132 |
| PLSCR1 |  | 10 | 167 | 412 | 408 | 0.202 | -0.159 | 0.091 | undef | -0.105 |
| PIK3R1 |  | 127 | 2 | 1 | 2 | -0.237 | 0.381 | 0.065 | undef | -0.002 |
| SKP2 |  | 29 | 45 | 1 | 23 | 0.092 | -0.043 | 0.237 | undef | -0.009 |
| ITGA5 |  | 26 | 52 | 179 | 177 | 0.031 | 0.192 | 0.125 | 0.133 | 0.202 |
| MEST |  | 1 | 1195 | 412 | 464 | 0.021 | 0.031 | 0.137 | 0.261 | -0.063 |
| TCERG1 |  | 4 | 440 | 412 | 419 | 0.098 | 0.093 | 0.172 | 0.228 | 0.105 |
| MGMT |  | 5 | 360 | 366 | 379 | 0.184 | -0.022 | 0.201 | undef | 0.196 |
| XK |  | 18 | 86 | 179 | 187 | 0.154 | -0.000 | 0.067 | -0.123 | -0.040 |
| NR2F1 |  | 25 | 59 | 83 | 92 | -0.252 | 0.113 | 0.133 | -0.116 | 0.207 |
| EGFR |  | 117 | 3 | 1 | 3 | -0.195 | 0.240 | -0.205 | -0.187 | 0.065 |
| BAIAP2 |  | 3 | 557 | 412 | 430 | -0.077 | -0.025 | 0.099 | 0.092 | -0.051 |
| PBX2 |  | 5 | 360 | 1 | 56 | -0.122 | -0.073 | 0.264 | -0.095 | 0.092 |
| GRB2 |  | 13 | 124 | 318 | 316 | -0.040 | -0.159 | -0.036 | -0.028 | -0.024 |
| INSR |  | 96 | 6 | 236 | 221 | 0.063 | 0.173 | 0.135 | -0.014 | -0.072 |
| ADAMTS5 |  | 2 | 743 | 412 | 439 | -0.066 | 0.021 | 0.211 | 0.180 | 0.030 |
| ALB |  | 3 | 557 | 412 | 430 | -0.122 | 0.218 | 0.080 | 0.018 | 0.038 |
| ITGA7 |  | 1 | 1195 | 412 | 464 | -0.081 | 0.038 | 0.153 | 0.063 | 0.121 |
| GRB7 |  | 58 | 18 | 1 | 12 | 0.021 | 0.115 | -0.072 | 0.229 | 0.129 |
| IGFBP5 |  | 48 | 23 | 83 | 80 | -0.076 | 0.110 | 0.074 | 0.278 | 0.181 |
| ACAN |  | 5 | 360 | 412 | 416 | 0.156 | 0.132 | -0.024 | -0.171 | -0.083 |
| PGM2L1 |  | 3 | 557 | 412 | 430 | -0.019 | 0.220 | undef | undef | undef |
| ATN1 |  | 7 | 256 | 412 | 414 | -0.005 | -0.093 | 0.005 | -0.185 | -0.136 |
| ITGAV |  | 1 | 1195 | 412 | 464 | -0.051 | 0.203 | 0.155 | -0.025 | 0.105 |
| DHRS1 |  | 1 | 1195 | 412 | 464 | 0.129 | 0.080 | 0.137 | undef | -0.053 |
| ITGB4 |  | 35 | 34 | 1 | 20 | 0.021 | 0.313 | -0.134 | 0.080 | -0.114 |
| SNRNP70 |  | 5 | 360 | 296 | 310 | -0.129 | 0.130 | -0.059 | -0.099 | 0.036 |
| ADK |  | 2 | 743 | 83 | 123 | 0.182 | -0.115 | 0.099 | undef | 0.094 |
| CCR5 |  | 2 | 743 | 412 | 439 | 0.153 | -0.276 | -0.159 | -0.156 | -0.067 |
GO Enrichment output for subnetwork 6619 in each dataset
| Name | Accession Number | Link | P-val | Corrected P-val |
| G1/S transition of mitotic cell cycle | GO:0000082 |  | 1.009E-09 | 2.464E-06 |
| regulation of cyclin-dependent protein kinase activity | GO:0000079 |  | 5.98E-09 | 7.305E-06 |
| cellular response to insulin stimulus | GO:0032869 |  | 7.549E-09 | 6.147E-06 |
| phospholipid dephosphorylation | GO:0046839 |  | 1.132E-08 | 6.913E-06 |
| regulation of mitochondrial membrane permeability | GO:0046902 |  | 1.132E-08 | 5.53E-06 |
| response to peptide hormone stimulus | GO:0043434 |  | 1.536E-08 | 6.255E-06 |
| insulin receptor signaling pathway | GO:0008286 |  | 2.776E-08 | 9.688E-06 |
| negative regulation of protein kinase B signaling cascade | GO:0051898 |  | 3.377E-08 | 1.031E-05 |
| response to insulin stimulus | GO:0032868 |  | 3.567E-08 | 9.682E-06 |
| cell-matrix adhesion | GO:0007160 |  | 6.091E-08 | 1.488E-05 |
| negative regulation of insulin receptor signaling pathway | GO:0046627 |  | 7.836E-08 | 1.74E-05 |
| Name | Accession Number | Link | P-val | Corrected P-val |
| G1/S transition of mitotic cell cycle | GO:0000082 |  | 1.877E-09 | 4.517E-06 |
| cellular response to insulin stimulus | GO:0032869 |  | 1.07E-08 | 1.287E-05 |
| regulation of cyclin-dependent protein kinase activity | GO:0000079 |  | 1.107E-08 | 8.879E-06 |
| phospholipid dephosphorylation | GO:0046839 |  | 1.562E-08 | 9.398E-06 |
| regulation of mitochondrial membrane permeability | GO:0046902 |  | 1.562E-08 | 7.518E-06 |
| response to peptide hormone stimulus | GO:0043434 |  | 1.923E-08 | 7.71E-06 |
| insulin receptor signaling pathway | GO:0008286 |  | 3.483E-08 | 1.197E-05 |
| negative regulation of protein kinase B signaling cascade | GO:0051898 |  | 4.659E-08 | 1.401E-05 |
| response to insulin stimulus | GO:0032868 |  | 5.252E-08 | 1.404E-05 |
| cell-matrix adhesion | GO:0007160 |  | 1.006E-07 | 2.421E-05 |
| negative regulation of insulin receptor signaling pathway | GO:0046627 |  | 1.081E-07 | 2.364E-05 |
| Name | Accession Number | Link | P-val | Corrected P-val |
| G1/S transition of mitotic cell cycle | GO:0000082 |  | 7.357E-09 | 1.692E-05 |
| cellular response to insulin stimulus | GO:0032869 |  | 3.133E-08 | 3.603E-05 |
| regulation of mitochondrial membrane permeability | GO:0046902 |  | 4.284E-08 | 3.284E-05 |
| response to peptide hormone stimulus | GO:0043434 |  | 7.468E-08 | 4.294E-05 |
| insulin receptor signaling pathway | GO:0008286 |  | 9.01E-08 | 4.145E-05 |
| cell-matrix adhesion | GO:0007160 |  | 1.288E-07 | 4.936E-05 |
| response to insulin stimulus | GO:0032868 |  | 1.743E-07 | 5.729E-05 |
| cell-substrate adhesion | GO:0031589 |  | 2.41E-07 | 6.929E-05 |
| negative regulation of insulin receptor signaling pathway | GO:0046627 |  | 2.953E-07 | 7.547E-05 |
| integrin-mediated signaling pathway | GO:0007229 |  | 4.425E-07 | 1.018E-04 |
| regulation of cyclin-dependent protein kinase activity | GO:0000079 |  | 5.868E-07 | 1.227E-04 |
VanDeVijver file
| Name | Accession Number | Link | P-val | Corrected P-val |
| response to peptide hormone stimulus | GO:0043434 |  | 7.707E-08 | 1.42E-04 |
| cellular response to insulin stimulus | GO:0032869 |  | 8.284E-08 | 7.633E-05 |
| cell-matrix adhesion | GO:0007160 |  | 1.743E-07 | 1.071E-04 |
| peptidyl-amino acid modification | GO:0018193 |  | 2.636E-07 | 1.215E-04 |
| response to insulin stimulus | GO:0032868 |  | 3.36E-07 | 1.238E-04 |
| cell-substrate adhesion | GO:0031589 |  | 3.594E-07 | 1.104E-04 |
| insulin receptor signaling pathway | GO:0008286 |  | 4.522E-07 | 1.191E-04 |
| integrin-mediated signaling pathway | GO:0007229 |  | 2.598E-06 | 5.984E-04 |
| cell-substrate junction assembly | GO:0007044 |  | 3.049E-06 | 6.244E-04 |
| mitochondrial membrane organization | GO:0007006 |  | 1.012E-05 | 1.864E-03 |
| cellular response to hormone stimulus | GO:0032870 |  | 1.142E-05 | 1.913E-03 |
| Name | Accession Number | Link | P-val | Corrected P-val |
| G1/S transition of mitotic cell cycle | GO:0000082 |  | 7.357E-09 | 1.692E-05 |
| cellular response to insulin stimulus | GO:0032869 |  | 3.133E-08 | 3.603E-05 |
| regulation of mitochondrial membrane permeability | GO:0046902 |  | 4.284E-08 | 3.284E-05 |
| response to peptide hormone stimulus | GO:0043434 |  | 7.468E-08 | 4.294E-05 |
| insulin receptor signaling pathway | GO:0008286 |  | 9.01E-08 | 4.145E-05 |
| cell-matrix adhesion | GO:0007160 |  | 1.288E-07 | 4.936E-05 |
| response to insulin stimulus | GO:0032868 |  | 1.743E-07 | 5.729E-05 |
| cell-substrate adhesion | GO:0031589 |  | 2.41E-07 | 6.929E-05 |
| negative regulation of insulin receptor signaling pathway | GO:0046627 |  | 2.953E-07 | 7.547E-05 |
| integrin-mediated signaling pathway | GO:0007229 |  | 4.425E-07 | 1.018E-04 |
| regulation of cyclin-dependent protein kinase activity | GO:0000079 |  | 5.868E-07 | 1.227E-04 |