Study Desmedt-ER-neg

Study informations

165 subnetworks in total page | file

2310 genes associated page | file

Enriched GO terms page

General informations

General Index page

Study Index page

Subnetwork 6619

score

DatasetScoreP-val 1P-val 2P-val 3Fisher Score
IPC0.75343.543e-035.780e-047.718e-011.581e-06
Loi0.23058.004e-021.130e-024.277e-013.867e-04
Schmidt0.67410.000e+000.000e+004.422e-020.000e+00
VanDeVijver0.79080.000e+000.000e+003.470e-030.000e+00
Wang0.26222.588e-034.299e-023.925e-014.367e-05

Expression data for subnetwork 6619 in each dataset

IPC | Loi | Schmidt | VanDeVijver | Wang |

Subnetwork structure for each dataset

Score for each gene in subnetwork 6619 in each dataset

Gene SymbolLinksFrequencyFrequency RankSubnetwork score rankGlobal rank IPCLoiSchmidtVanDeVijverWang
EP300EP300 on ITI EP300 on NCBI113414-0.1490.0870.1020.0520.025
CCNE2CCNE2 on ITI CCNE2 on NCBI111484124070.136-0.1780.241undef-0.055
SORBS1SORBS1 on ITI SORBS1 on NCBI5719113-0.0430.0150.314-0.0720.200
DUSP8DUSP8 on ITI DUSP8 on NCBI44401590.1180.2570.0680.208-0.029
SF3B1SF3B1 on ITI SF3B1 on NCBI1886296280-0.1540.126-0.073-0.131-0.204
RETRET on ITI RET on NCBI72563663760.0980.063-0.179undef-0.159
TP53TP53 on ITI TP53 on NCBI85716-0.1670.148-0.0270.2520.147
TPX2TPX2 on ITI TPX2 on NCBI53604124160.114-0.121-0.018undef-0.056
ERBB2ERBB2 on ITI ERBB2 on NCBI141111-0.1030.092-0.0900.2670.046
PTP4A3PTP4A3 on ITI PTP4A3 on NCBI91964124110.137-0.1960.085undef-0.004
IRX4IRX4 on ITI IRX4 on NCBI2743412439-0.0120.137-0.018-0.1390.125
ID4ID4 on ITI ID4 on NCBI3534236223-0.1790.1370.241undef0.036
CDKN1ACDKN1A on ITI CDKN1A on NCBI1105150.0640.2540.030undef0.082
PRKCAPRKCA on ITI PRKCA on NCBI6315110-0.016-0.0880.1740.0950.005
BARD1BARD1 on ITI BARD1 on NCBI69121411320.179-0.1650.0860.245-0.104
GRM5GRM5 on ITI GRM5 on NCBI151111791910.094-0.0190.0000.093-0.093
CCND1CCND1 on ITI CCND1 on NCBI2652124-0.2580.0740.117undef0.003
CCNA2CCNA2 on ITI CCNA2 on NCBI21731791830.176-0.0530.188-0.0780.246
PCNAPCNA on ITI PCNA on NCBI151111320.243-0.1580.027-0.0990.003
SNRPD1SNRPD1 on ITI SNRPD1 on NCBI27434124390.140-0.2110.198-0.045-0.008
PIN1PIN1 on ITI PIN1 on NCBI24621791810.1940.040-0.0400.065-0.048
TWIST1TWIST1 on ITI TWIST1 on NCBI50201140.0440.1940.061undef0.219
ACOX2ACOX2 on ITI ACOX2 on NCBI35574124300.0130.100-0.0210.1340.047
KITKIT on ITI KIT on NCBI3929118-0.130-0.0910.235-0.046-0.059
STRAPSTRAP on ITI STRAP on NCBI72564124140.035-0.1280.0740.154-0.049
AFG3L2AFG3L2 on ITI AFG3L2 on NCBI111954124640.013-0.2110.098-0.131-0.010
CCL15CCL15 on ITI CCL15 on NCBI2743412439-0.1900.0040.141-0.2150.007
PDK1PDK1 on ITI PDK1 on NCBI101671400.183-0.138-0.041-0.265-0.126
DPM1DPM1 on ITI DPM1 on NCBI111954124640.177-0.0720.133-0.0250.009
PPARGPPARG on ITI PPARG on NCBI7256179201-0.1190.0110.1050.0590.039
AKT2AKT2 on ITI AKT2 on NCBI28474123940.110-0.118-0.0030.088-0.092
SUMO3SUMO3 on ITI SUMO3 on NCBI35574124300.1260.0810.0870.138-0.073
MMP1MMP1 on ITI MMP1 on NCBI111483663600.1920.0140.0360.0440.260
GLO1GLO1 on ITI GLO1 on NCBI5360831100.266-0.0890.1350.1000.076
LUC7LLUC7L on ITI LUC7L on NCBI11195412464-0.029-0.0250.102-0.018-0.019
RCN2RCN2 on ITI RCN2 on NCBI35574124300.0590.0510.1760.008-0.098
CDK1CDK1 on ITI CDK1 on NCBI631583790.265-0.1950.1060.0880.031
AHSGAHSG on ITI AHSG on NCBI5360412416-0.113-0.0540.0000.132undef
AGPAT2AGPAT2 on ITI AGPAT2 on NCBI35574124300.167-0.0150.1230.042-0.076
LUC7L3LUC7L3 on ITI LUC7L3 on NCBI161042962810.0430.2370.1750.1350.074
CLCA2CLCA2 on ITI CLCA2 on NCBI9196412411-0.1760.243-0.1530.191-0.000
CCNA1CCNA1 on ITI CCNA1 on NCBI33374123930.1740.0920.0780.055-0.098
TNFRSF1ATNFRSF1A on ITI TNFRSF1A on NCBI82224124130.0500.094-0.0140.214-0.045
ITGB1ITGB1 on ITI ITGB1 on NCBI111954124640.0160.0930.154undef0.074
GSK3BGSK3B on ITI GSK3B on NCBI798179169-0.1300.292-0.1290.2910.057
KLF5KLF5 on ITI KLF5 on NCBI769170.0770.117-0.007-0.110-0.006
PSPHPSPH on ITI PSPH on NCBI20813663560.240-0.019-0.1020.3580.025
NCOR2NCOR2 on ITI NCOR2 on NCBI3240318290-0.0960.211-0.1630.1580.114
GYG2GYG2 on ITI GYG2 on NCBI27434124390.092-0.0150.0200.189-0.004
CX3CR1CX3CR1 on ITI CX3CR1 on NCBI2743412439-0.2130.0600.113-0.040-0.050
GSTT1GSTT1 on ITI GSTT1 on NCBI151111320.1480.107-0.1900.022-0.064
IGF2BP2IGF2BP2 on ITI IGF2BP2 on NCBI27434124390.210-0.0020.098-0.098-0.122
KIAA1377KIAA1377 on ITI KIAA1377 on NCBI1886141136-0.0950.116undef0.198undef
IKBKAPIKBKAP on ITI IKBKAP on NCBI101674124080.0890.1840.1420.105-0.017
ITGB5ITGB5 on ITI ITGB5 on NCBI44404124190.1630.2080.0810.2780.148
COPG2COPG2 on ITI COPG2 on NCBI4440412419-0.058-0.2320.0000.086-0.081
ADAADA on ITI ADA on NCBI4440831120.208-0.164-0.042-0.1020.219
TOP2ATOP2A on ITI TOP2A on NCBI20811280.193-0.1680.054-0.0640.071
SPP1SPP1 on ITI SPP1 on NCBI265283910.1300.1190.1840.2040.153
CCR1CCR1 on ITI CCR1 on NCBI27434124390.162-0.205-0.049-0.123-0.109
PTENPTEN on ITI PTEN on NCBI27501411350.0450.0550.0170.183-0.041
MYCMYC on ITI MYC on NCBI721018-0.101-0.1690.188undef-0.134
CCL4CCL4 on ITI CCL4 on NCBI111954124640.211-0.334-0.065-0.1660.003
BCL2BCL2 on ITI BCL2 on NCBI37328382-0.077-0.0350.128-0.1060.043
BNIP3BNIP3 on ITI BNIP3 on NCBI111482362320.1930.0710.1020.1190.285
ERRFI1ERRFI1 on ITI ERRFI1 on NCBI101674124080.0760.215undef-0.043undef
C1orf103C1orf103 on ITI C1orf103 on NCBI44404124190.0570.029-0.1730.127-0.159
DLX4DLX4 on ITI DLX4 on NCBI101672362340.2910.057-0.004undef-0.059
MYBMYB on ITI MYB on NCBI2847366344-0.0280.0750.0020.065-0.012
DUSP1DUSP1 on ITI DUSP1 on NCBI4440159-0.0190.1270.170-0.0310.134
MN1MN1 on ITI MN1 on NCBI3557366389-0.166-0.0470.1500.0100.011
CCL7CCL7 on ITI CCL7 on NCBI27434124390.204-0.1420.011undef-0.140
PNPPNP on ITI PNP on NCBI27434124390.036-0.0120.108-0.0400.132
PLSCR1PLSCR1 on ITI PLSCR1 on NCBI101674124080.202-0.1590.091undef-0.105
PIK3R1PIK3R1 on ITI PIK3R1 on NCBI127212-0.2370.3810.065undef-0.002
SKP2SKP2 on ITI SKP2 on NCBI29451230.092-0.0430.237undef-0.009
ITGA5ITGA5 on ITI ITGA5 on NCBI26521791770.0310.1920.1250.1330.202
MESTMEST on ITI MEST on NCBI111954124640.0210.0310.1370.261-0.063
TCERG1TCERG1 on ITI TCERG1 on NCBI44404124190.0980.0930.1720.2280.105
MGMTMGMT on ITI MGMT on NCBI53603663790.184-0.0220.201undef0.196
XKXK on ITI XK on NCBI18861791870.154-0.0000.067-0.123-0.040
NR2F1NR2F1 on ITI NR2F1 on NCBI25598392-0.2520.1130.133-0.1160.207
EGFREGFR on ITI EGFR on NCBI117313-0.1950.240-0.205-0.1870.065
BAIAP2BAIAP2 on ITI BAIAP2 on NCBI3557412430-0.077-0.0250.0990.092-0.051
PBX2PBX2 on ITI PBX2 on NCBI5360156-0.122-0.0730.264-0.0950.092
GRB2GRB2 on ITI GRB2 on NCBI13124318316-0.040-0.159-0.036-0.028-0.024
INSRINSR on ITI INSR on NCBI9662362210.0630.1730.135-0.014-0.072
ADAMTS5ADAMTS5 on ITI ADAMTS5 on NCBI2743412439-0.0660.0210.2110.1800.030
ALBALB on ITI ALB on NCBI3557412430-0.1220.2180.0800.0180.038
ITGA7ITGA7 on ITI ITGA7 on NCBI11195412464-0.0810.0380.1530.0630.121
GRB7GRB7 on ITI GRB7 on NCBI58181120.0210.115-0.0720.2290.129
IGFBP5IGFBP5 on ITI IGFBP5 on NCBI48238380-0.0760.1100.0740.2780.181
ACANACAN on ITI ACAN on NCBI53604124160.1560.132-0.024-0.171-0.083
PGM2L1PGM2L1 on ITI PGM2L1 on NCBI3557412430-0.0190.220undefundefundef
ATN1ATN1 on ITI ATN1 on NCBI7256412414-0.005-0.0930.005-0.185-0.136
ITGAVITGAV on ITI ITGAV on NCBI11195412464-0.0510.2030.155-0.0250.105
DHRS1DHRS1 on ITI DHRS1 on NCBI111954124640.1290.0800.137undef-0.053
ITGB4ITGB4 on ITI ITGB4 on NCBI35341200.0210.313-0.1340.080-0.114
SNRNP70SNRNP70 on ITI SNRNP70 on NCBI5360296310-0.1290.130-0.059-0.0990.036
ADKADK on ITI ADK on NCBI2743831230.182-0.1150.099undef0.094
CCR5CCR5 on ITI CCR5 on NCBI27434124390.153-0.276-0.159-0.156-0.067

GO Enrichment output for subnetwork 6619 in each dataset

IPC file

NameAccession NumberLinkP-valCorrected P-val
G1/S transition of mitotic cell cycleGO:0000082GO:0000082 on GO1.009E-092.464E-06
regulation of cyclin-dependent protein kinase activityGO:0000079GO:0000079 on GO5.98E-097.305E-06
cellular response to insulin stimulusGO:0032869GO:0032869 on GO7.549E-096.147E-06
phospholipid dephosphorylationGO:0046839GO:0046839 on GO1.132E-086.913E-06
regulation of mitochondrial membrane permeabilityGO:0046902GO:0046902 on GO1.132E-085.53E-06
response to peptide hormone stimulusGO:0043434GO:0043434 on GO1.536E-086.255E-06
insulin receptor signaling pathwayGO:0008286GO:0008286 on GO2.776E-089.688E-06
negative regulation of protein kinase B signaling cascadeGO:0051898GO:0051898 on GO3.377E-081.031E-05
response to insulin stimulusGO:0032868GO:0032868 on GO3.567E-089.682E-06
cell-matrix adhesionGO:0007160GO:0007160 on GO6.091E-081.488E-05
negative regulation of insulin receptor signaling pathwayGO:0046627GO:0046627 on GO7.836E-081.74E-05


Loi file

NameAccession NumberLinkP-valCorrected P-val
G1/S transition of mitotic cell cycleGO:0000082GO:0000082 on GO1.877E-094.517E-06
cellular response to insulin stimulusGO:0032869GO:0032869 on GO1.07E-081.287E-05
regulation of cyclin-dependent protein kinase activityGO:0000079GO:0000079 on GO1.107E-088.879E-06
phospholipid dephosphorylationGO:0046839GO:0046839 on GO1.562E-089.398E-06
regulation of mitochondrial membrane permeabilityGO:0046902GO:0046902 on GO1.562E-087.518E-06
response to peptide hormone stimulusGO:0043434GO:0043434 on GO1.923E-087.71E-06
insulin receptor signaling pathwayGO:0008286GO:0008286 on GO3.483E-081.197E-05
negative regulation of protein kinase B signaling cascadeGO:0051898GO:0051898 on GO4.659E-081.401E-05
response to insulin stimulusGO:0032868GO:0032868 on GO5.252E-081.404E-05
cell-matrix adhesionGO:0007160GO:0007160 on GO1.006E-072.421E-05
negative regulation of insulin receptor signaling pathwayGO:0046627GO:0046627 on GO1.081E-072.364E-05


Schmidt file

NameAccession NumberLinkP-valCorrected P-val
G1/S transition of mitotic cell cycleGO:0000082GO:0000082 on GO7.357E-091.692E-05
cellular response to insulin stimulusGO:0032869GO:0032869 on GO3.133E-083.603E-05
regulation of mitochondrial membrane permeabilityGO:0046902GO:0046902 on GO4.284E-083.284E-05
response to peptide hormone stimulusGO:0043434GO:0043434 on GO7.468E-084.294E-05
insulin receptor signaling pathwayGO:0008286GO:0008286 on GO9.01E-084.145E-05
cell-matrix adhesionGO:0007160GO:0007160 on GO1.288E-074.936E-05
response to insulin stimulusGO:0032868GO:0032868 on GO1.743E-075.729E-05
cell-substrate adhesionGO:0031589GO:0031589 on GO2.41E-076.929E-05
negative regulation of insulin receptor signaling pathwayGO:0046627GO:0046627 on GO2.953E-077.547E-05
integrin-mediated signaling pathwayGO:0007229GO:0007229 on GO4.425E-071.018E-04
regulation of cyclin-dependent protein kinase activityGO:0000079GO:0000079 on GO5.868E-071.227E-04


VanDeVijver file

NameAccession NumberLinkP-valCorrected P-val
response to peptide hormone stimulusGO:0043434GO:0043434 on GO7.707E-081.42E-04
cellular response to insulin stimulusGO:0032869GO:0032869 on GO8.284E-087.633E-05
cell-matrix adhesionGO:0007160GO:0007160 on GO1.743E-071.071E-04
peptidyl-amino acid modificationGO:0018193GO:0018193 on GO2.636E-071.215E-04
response to insulin stimulusGO:0032868GO:0032868 on GO3.36E-071.238E-04
cell-substrate adhesionGO:0031589GO:0031589 on GO3.594E-071.104E-04
insulin receptor signaling pathwayGO:0008286GO:0008286 on GO4.522E-071.191E-04
integrin-mediated signaling pathwayGO:0007229GO:0007229 on GO2.598E-065.984E-04
cell-substrate junction assemblyGO:0007044GO:0007044 on GO3.049E-066.244E-04
mitochondrial membrane organizationGO:0007006GO:0007006 on GO1.012E-051.864E-03
cellular response to hormone stimulusGO:0032870GO:0032870 on GO1.142E-051.913E-03


Wang file

NameAccession NumberLinkP-valCorrected P-val
G1/S transition of mitotic cell cycleGO:0000082GO:0000082 on GO7.357E-091.692E-05
cellular response to insulin stimulusGO:0032869GO:0032869 on GO3.133E-083.603E-05
regulation of mitochondrial membrane permeabilityGO:0046902GO:0046902 on GO4.284E-083.284E-05
response to peptide hormone stimulusGO:0043434GO:0043434 on GO7.468E-084.294E-05
insulin receptor signaling pathwayGO:0008286GO:0008286 on GO9.01E-084.145E-05
cell-matrix adhesionGO:0007160GO:0007160 on GO1.288E-074.936E-05
response to insulin stimulusGO:0032868GO:0032868 on GO1.743E-075.729E-05
cell-substrate adhesionGO:0031589GO:0031589 on GO2.41E-076.929E-05
negative regulation of insulin receptor signaling pathwayGO:0046627GO:0046627 on GO2.953E-077.547E-05
integrin-mediated signaling pathwayGO:0007229GO:0007229 on GO4.425E-071.018E-04
regulation of cyclin-dependent protein kinase activityGO:0000079GO:0000079 on GO5.868E-071.227E-04


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