pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6619-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! response to peptide hormone stimulus GO:0043434 36 34 6,000 7,707E-08 1,42E-04 ! cellular response to insulin stimulus GO:0032869 23 21 5,000 8,284E-08 7,633E-05 ! cell-matrix adhesion GO:0007160 39 38 6,000 1,743E-07 1,071E-04 ! peptidyl-amino acid modification GO:0018193 61 59 7,000 2,636E-07 1,215E-04 ! response to insulin stimulus GO:0032868 28 26 5,000 3,36E-07 1,238E-04 ! cell-substrate adhesion GO:0031589 43 42 6,000 3,594E-07 1,104E-04 ! insulin receptor signaling pathway GO:0008286 17 15 4,000 4,522E-07 1,191E-04 ! integrin-mediated signaling pathway GO:0007229 36 36 5,000 2,598E-06 5,984E-04 ! cell-substrate junction assembly GO:0007044 11 10 3,000 3,049E-06 6,244E-04 ! mitochondrial membrane organization GO:0007006 13 13 3,000 1,012E-05 1,864E-03 ! cellular response to hormone stimulus GO:0032870 48 46 5,000 1,142E-05 1,913E-03 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 2,000 1,379E-05 2,119E-03 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! T cell lineage commitment GO:0002360 5 5 2,000 1,379E-05 1,956E-03 ! ER overload response GO:0006983 6 6 2,000 2,736E-05 3,602E-03 ! focal adhesion formation GO:0048041 7 6 2,000 2,736E-05 3,362E-03 ! peptidyl-serine phosphorylation GO:0018105 6 6 2,000 2,736E-05 3,152E-03 ! negative regulation of ossification GO:0030279 6 6 2,000 2,736E-05 2,966E-03 ! protein amino acid dephosphorylation GO:0006470 55 54 5,000 2,93E-05 3E-03 ! cell junction assembly GO:0034329 18 17 3,000 3,253E-05 3,156E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 3,000 4,147E-05 3,821E-03 ! response to gamma radiation GO:0010332 8 7 2,000 4,749E-05 4,168E-03 ! dephosphorylation GO:0016311 60 59 5,000 4,886E-05 4,093E-03 ! negative regulation of bone remodeling GO:0046851 8 8 2,000 7,537E-05 6,039E-03 ! peptidyl-serine modification GO:0018209 8 8 2,000 7,537E-05 5,788E-03 ! release of cytochrome c from mitochondria GO:0001836 9 8 2,000 7,537E-05 5,556E-03 ! regulation of MAP kinase activity GO:0043405 67 66 5,000 9,253E-05 6,559E-03 ! cell junction organization GO:0034330 23 22 3,000 9,577E-05 6,537E-03 ! negative regulation of tissue remodeling GO:0034104 9 9 2,000 1,121E-04 7,381E-03 ! defense response to virus GO:0051607 9 9 2,000 1,121E-04 7,126E-03 ! response to nutrient levels GO:0031667 69 69 5,000 1,188E-04 7,301E-03 ! response to hormone stimulus GO:0009725 102 100 6,000 1,261E-04 7,494E-03 ! mitochondrial transport GO:0006839 24 24 3,000 1,367E-04 7,876E-03 ! regulation of cell migration GO:0030334 71 71 5,000 1,395E-04 7,788E-03 ! response to extracellular stimulus GO:0009991 72 72 5,000 1,508E-04 8,173E-03 ! regulation of membrane potential GO:0042391 46 46 4,000 1,569E-04 8,26E-03 ! apoptotic mitochondrial changes GO:0008637 11 10 2,000 1,589E-04 8,134E-03 ! purine ribonucleoside metabolic process GO:0046128 10 10 2,000 1,589E-04 7,914E-03 GO:0042278|purine nucleoside metabolic process, ! neuromuscular junction development GO:0007528 10 10 2,000 1,589E-04 7,706E-03 ! gut development GO:0048565 10 10 2,000 1,589E-04 7,508E-03 ! negative regulation of cell migration GO:0030336 26 26 3,000 1,891E-04 8,713E-03 ! regulation of T cell differentiation GO:0045580 26 26 3,000 1,891E-04 8,501E-03 ! positive regulation of MAP kinase activity GO:0043406 50 49 4,000 2,125E-04 9,325E-03 ! regulation of viral genome replication GO:0045069 11 11 2,000 2,167E-04 9,287E-03 ! cellular response to starvation GO:0009267 11 11 2,000 2,167E-04 9,076E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 2,000 2,167E-04 8,874E-03 ! apoptotic nuclear changes GO:0030262 11 11 2,000 2,167E-04 8,681E-03 ! interaction with host GO:0051701 11 11 2,000 2,167E-04 8,497E-03 ! regulation of locomotion GO:0040012 79 79 5,000 2,519E-04 9,672E-03 ! regulation of cell motion GO:0051270 79 79 5,000 2,519E-04 9,475E-03 ! protein amino acid autophosphorylation GO:0046777 28 28 3,000 2,546E-04 9,384E-03 ! neuron projection development GO:0031175 85 80 5,000 2,699E-04 9,754E-03 ! negative regulation of translation GO:0017148 12 12 2,000 2,865E-04 0,01015598 ! viral reproductive process GO:0022415 29 29 3,000 2,928E-04 0,01018155 ! response to UV GO:0009411 29 29 3,000 2,928E-04 9,993E-03 ! response to hypoxia GO:0001666 53 53 4,000 3,087E-04 0,01034456 ! response to oxygen levels GO:0070482 55 54 4,000 3,372E-04 0,01109817 ! regulation of cell adhesion GO:0030155 56 55 4,000 3,677E-04 0,01188844 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 2,000 3,695E-04 0,01174054 ! cell aging GO:0007569 13 13 2,000 3,695E-04 0,01154154 ! response to endoplasmic reticulum stress GO:0034976 13 13 2,000 3,695E-04 0,01134918 ! regulation of viral reproduction GO:0050792 13 13 2,000 3,695E-04 0,01116313 ! regulation of cell-substrate adhesion GO:0010810 14 13 2,000 3,695E-04 0,01098308 GO:0001952|regulation of cell-matrix adhesion, ! tissue homeostasis GO:0001894 13 13 2,000 3,695E-04 0,01080875 GO:0048871|multicellular organismal homeostasis, ! protein tetramerization GO:0051262 13 13 2,000 3,695E-04 0,01063986 ! regulation of DNA replication GO:0006275 32 31 3,000 3,813E-04 0,01081085 ! negative regulation of cell motion GO:0051271 31 31 3,000 3,813E-04 0,01064705 ! heart development GO:0007507 90 87 5,000 4,26E-04 0,01171755 ! regulation of lymphocyte differentiation GO:0045619 32 32 3,000 4,32E-04 0,01170919 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 2,000 4,664E-04 0,01245808 ! base-excision repair GO:0006284 14 14 2,000 4,664E-04 0,0122801 ! negative regulation of cell cycle GO:0045786 92 91 5,000 5,425E-04 0,01408174 ! viral reproduction GO:0016032 34 34 3,000 5,477E-04 0,01401911 ! ER-nuclear signaling pathway GO:0006984 15 15 2,000 5,783E-04 0,01459949 ! response to starvation GO:0042594 15 15 2,000 5,783E-04 0,0144022 ! response to ionizing radiation GO:0010212 16 15 2,000 5,783E-04 0,01421017 ! axonogenesis GO:0007409 66 62 4,000 6,43E-04 0,01559281 ! positive regulation of cell migration GO:0030335 36 36 3,000 6,838E-04 0,016367 ! cellular response to nutrient levels GO:0031669 16 16 2,000 7,059E-04 0,01667995 ! positive regulation of catabolic process GO:0009896 16 16 2,000 7,059E-04 0,01646881 ! myelination GO:0042552 17 17 2,000 8,502E-04 0,01958727 ! response to toxin GO:0009636 18 17 2,000 8,502E-04 0,01934545 ! pigmentation GO:0043473 17 17 2,000 8,502E-04 0,01910953 ! muscle organ development GO:0007517 102 100 5,000 8,951E-04 0,01987446 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 4,000 9,183E-04 0,02014784 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! striated muscle tissue development GO:0014706 69 67 4,000 9,183E-04 0,01991081 ! cytokine-mediated signaling pathway GO:0019221 39 39 3,000 9,306E-04 0,0199425 ! positive regulation of cell motion GO:0051272 39 39 3,000 9,306E-04 0,01971328 ! response to radiation GO:0009314 70 68 4,000 9,825E-04 0,0205764 ! B cell differentiation GO:0030183 18 18 2,000 1,012E-03 0,02095609 ! cellular response to extracellular stimulus GO:0031668 18 18 2,000 1,012E-03 0,02072325 ! ensheathment of neurons GO:0007272 18 18 2,000 1,012E-03 0,02049552 GO:0008366|axon ensheathment, ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 2,000 1,012E-03 0,02027274 ! regulation of mitotic cell cycle GO:0007346 72 69 4,000 1,05E-03 0,02080726 ! cell part morphogenesis GO:0032990 75 70 4,000 1,121E-03 0,02197515 ! muscle tissue development GO:0060537 72 70 4,000 1,121E-03 0,02174384 ! DNA damage checkpoint GO:0000077 19 19 2,000 1,192E-03 0,02288335 ! regulation of striated muscle tissue development GO:0016202 20 19 2,000 1,192E-03 0,02264744 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 2,000 1,192E-03 0,02241634 ! ribonucleoside metabolic process GO:0009119 19 19 2,000 1,192E-03 0,02218992 ! positive regulation of T cell differentiation GO:0045582 19 19 2,000 1,192E-03 0,02196802 ! regulation of protein stability GO:0031647 19 19 2,000 1,192E-03 0,02175051 ! placenta development GO:0001890 19 19 2,000 1,192E-03 0,02153727 ! negative regulation of signal transduction GO:0009968 71 71 4,000 1,195E-03 0,02138528 ! positive regulation of glucose metabolic process GO:0010907 5 5 1,000 1,241E-03 0,02199573 ! metencephalon development GO:0022037 5 5 1,000 1,241E-03 0,02178624 ! filopodium assembly GO:0046847 7 5 1,000 1,241E-03 0,02158071 GO:0030035|microspike assembly, ! memory GO:0007613 5 5 1,000 1,241E-03 0,02137902 ! response to lipid GO:0033993 5 5 1,000 1,241E-03 0,02118107 ! regulation of phospholipase A2 activity GO:0032429 5 5 1,000 1,241E-03 0,02098675 ! fear response GO:0042596 5 5 1,000 1,241E-03 0,02079596 ! wound healing, spreading of epidermal cells GO:0035313 5 5 1,000 1,241E-03 0,02060861 ! protein heterooligomerization GO:0051291 5 5 1,000 1,241E-03 0,0204246 ! response to UV-B GO:0010224 5 5 1,000 1,241E-03 0,02024385 ! interaction with symbiont GO:0051702 5 5 1,000 1,241E-03 0,02006628 ! positive regulation of phagocytosis GO:0050766 5 5 1,000 1,241E-03 0,01989179 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 1,000 1,241E-03 0,01972031 ! negative regulation of focal adhesion formation GO:0051895 6 5 1,000 1,241E-03 0,01955176 ! regulation of mitochondrial membrane potential GO:0051881 5 5 1,000 1,241E-03 0,01938606 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 1,000 1,241E-03 0,01922316 GO:0009155|purine deoxyribonucleotide catabolic process, ! cellular pigmentation GO:0033059 5 5 1,000 1,241E-03 0,01906296 ! peptidyl-lysine modification GO:0018205 5 5 1,000 1,241E-03 0,01890542 ! negative regulation of neuroblast proliferation GO:0007406 5 5 1,000 1,241E-03 0,01875046 ! peptidyl-histidine modification GO:0018202 5 5 1,000 1,241E-03 0,01859801 ! oocyte differentiation GO:0009994 5 5 1,000 1,241E-03 0,01844803 GO:0048599|oocyte development, ! regulation of protein homodimerization activity GO:0043496 6 5 1,000 1,241E-03 0,01830044 ! spleen development GO:0048536 5 5 1,000 1,241E-03 0,0181552 ! positive regulation of viral reproduction GO:0048524 5 5 1,000 1,241E-03 0,01801225 ! blastocyst formation GO:0001825 5 5 1,000 1,241E-03 0,01787153 ! embryonic gut development GO:0048566 5 5 1,000 1,241E-03 0,01773299 ! response to nicotine GO:0035094 5 5 1,000 1,241E-03 0,01759658 ! mitochondrion localization GO:0051646 5 5 1,000 1,241E-03 0,01746226 ! mitochondrion organization GO:0007005 44 43 3,000 1,349E-03 0,01883794 ! regulation of muscle development GO:0048634 21 20 2,000 1,391E-03 0,01927431 ! nucleus organization GO:0006997 20 20 2,000 1,391E-03 0,01913047 ! peptidyl-tyrosine modification GO:0018212 21 20 2,000 1,391E-03 0,01898876 ! phosphoinositide-mediated signaling GO:0048015 45 45 3,000 1,601E-03 0,02169981 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 2,000 1,61E-03 0,02165294 ! DNA integrity checkpoint GO:0031570 21 21 2,000 1,61E-03 0,02149603 ! regulation of action potential in neuron GO:0019228 21 21 2,000 1,61E-03 0,02134138 ! regulation of multicellular organism growth GO:0040014 21 21 2,000 1,61E-03 0,02118895 ! negative regulation of cell communication GO:0010648 76 76 4,000 1,623E-03 0,02121317 ! cell morphogenesis involved in differentiation GO:0000904 82 77 4,000 1,72E-03 0,02232937 ! glucan biosynthetic process GO:0009250 6 6 1,000 1,848E-03 0,02381901 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 1,000 1,848E-03 0,0236536 ! regulation of phagocytosis GO:0050764 6 6 1,000 1,848E-03 0,02349047 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 1,000 1,848E-03 0,02332958 ! regulation of focal adhesion formation GO:0051893 7 6 1,000 1,848E-03 0,02317088 ! N-terminal protein amino acid modification GO:0031365 6 6 1,000 1,848E-03 0,02301432 GO:0018409|peptide or protein amino-terminal blocking, ! virus-host interaction GO:0019048 6 6 1,000 1,848E-03 0,02285986 ! bile acid metabolic process GO:0008206 6 6 1,000 1,848E-03 0,02270746 ! negative regulation of T cell proliferation GO:0042130 6 6 1,000 1,848E-03 0,02255708 GO:0070667|negative regulation of mast cell proliferation, ! G1 DNA damage checkpoint GO:0031571 6 6 1,000 1,848E-03 0,02240868 ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 1,848E-03 0,02226221 ! cellular metabolic compound salvage GO:0043094 6 6 1,000 1,848E-03 0,02211765 ! serine family amino acid biosynthetic process GO:0009070 6 6 1,000 1,848E-03 0,02197496 ! thymus development GO:0048538 6 6 1,000 1,848E-03 0,02183409 ! regulation of RNA splicing GO:0043484 6 6 1,000 1,848E-03 0,02169502 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 1,000 1,848E-03 0,02155771 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! regulation of embryonic development GO:0045995 6 6 1,000 1,848E-03 0,02142213 ! localization within membrane GO:0051668 6 6 1,000 1,848E-03 0,02128824 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 2,000 1,849E-03 0,0211613 ! viral infectious cycle GO:0019058 23 23 2,000 2,109E-03 0,02398913 ! mitotic cell cycle checkpoint GO:0007093 24 23 2,000 2,109E-03 0,02384196 ! positive regulation of growth GO:0045927 23 23 2,000 2,109E-03 0,02369658 ! cell projection assembly GO:0030031 25 23 2,000 2,109E-03 0,02355296 ! leukocyte differentiation GO:0002521 50 49 3,000 2,201E-03 0,02443103 ! ossification GO:0001503 50 49 3,000 2,201E-03 0,02428474 GO:0060348|bone development, ! skeletal muscle tissue development GO:0007519 50 49 3,000 2,201E-03 0,02414019 GO:0060538|skeletal muscle organ development, ! response to nutrient GO:0007584 49 49 3,000 2,201E-03 0,02399735 ! regulation of DNA metabolic process GO:0051052 51 50 3,000 2,372E-03 0,02571 ! T cell activation GO:0042110 51 50 3,000 2,372E-03 0,02555965 ! regulation of action potential GO:0001508 24 24 2,000 2,39E-03 0,02561286 ! glucose homeostasis GO:0042593 24 24 2,000 2,39E-03 0,02546481 GO:0033500|carbohydrate homeostasis, ! T cell differentiation GO:0030217 24 24 2,000 2,39E-03 0,02531846 ! glucan metabolic process GO:0044042 25 24 2,000 2,39E-03 0,02517378 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! positive regulation of cellular catabolic process GO:0031331 7 7 1,000 2,568E-03 0,02689519 ! hair follicle morphogenesis GO:0031069 7 7 1,000 2,568E-03 0,02674324 ! negative regulation of striated muscle development GO:0045843 7 7 1,000 2,568E-03 0,026593 ! digestive system development GO:0055123 7 7 1,000 2,568E-03 0,02644444 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! regulation of mRNA processing GO:0050684 7 7 1,000 2,568E-03 0,02629752 ! regulation of skeletal muscle fiber development GO:0048742 7 7 1,000 2,568E-03 0,02615223 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 1,000 2,568E-03 0,02600854 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! cardiac muscle tissue development GO:0048738 7 7 1,000 2,568E-03 0,02586642 ! response to X-ray GO:0010165 7 7 1,000 2,568E-03 0,02572584 ! regulation of intracellular pH GO:0051453 7 7 1,000 2,568E-03 0,02558678 ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 1,000 2,568E-03 0,02544922 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! alpha-beta T cell differentiation GO:0046632 7 7 1,000 2,568E-03 0,02531312 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 1,000 2,568E-03 0,02517848 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 1,000 2,568E-03 0,02504526 GO:0001953|negative regulation of cell-matrix adhesion, ! cell killing GO:0001906 7 7 1,000 2,568E-03 0,02491344 ! negative regulation of T cell activation GO:0050868 7 7 1,000 2,568E-03 0,02478301 ! positive regulation of cell differentiation GO:0045597 87 85 4,000 2,662E-03 0,02555637 ! regulation of gene-specific transcription GO:0032583 25 25 2,000 2,694E-03 0,02572843 ! regulation of intracellular protein transport GO:0033157 25 25 2,000 2,694E-03 0,02559581 ! regulation of T cell proliferation GO:0042129 25 25 2,000 2,694E-03 0,02546455 ! cell fate commitment GO:0045165 52 52 3,000 2,741E-03 0,02576976 ! response to light stimulus GO:0009416 53 52 3,000 2,741E-03 0,02563895 ! positive regulation of protein kinase activity GO:0045860 89 86 4,000 2,802E-03 0,02608176 ! regulation of T cell activation GO:0050863 53 53 3,000 2,939E-03 0,02721982 ! synapse organization GO:0050808 26 26 2,000 3,021E-03 0,02783905 ! positive regulation of transferase activity GO:0051347 91 88 4,000 3,097E-03 0,02839844 GO:0033674|positive regulation of kinase activity, ! response to virus GO:0009615 54 54 3,000 3,147E-03 0,02871467 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 2,000 3,371E-03 0,03060631 ! energy reserve metabolic process GO:0006112 28 27 2,000 3,371E-03 0,03045628 ! regulation of skeletal muscle tissue development GO:0048641 8 8 1,000 3,399E-03 0,03056148 ! negative regulation of muscle development GO:0048635 8 8 1,000 3,399E-03 0,03041313 ! T cell selection GO:0045058 8 8 1,000 3,399E-03 0,0302662 ! sex determination GO:0007530 8 8 1,000 3,399E-03 0,03012069 ! negative regulation of mitotic cell cycle GO:0045930 9 8 1,000 3,399E-03 0,02997657 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 1,000 3,399E-03 0,02983383 ! alpha-beta T cell activation GO:0046631 8 8 1,000 3,399E-03 0,02969244 ! nucleoside triphosphate catabolic process GO:0009143 8 8 1,000 3,399E-03 0,02955238 ! T cell homeostasis GO:0043029 8 8 1,000 3,399E-03 0,02941363 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 1,000 3,399E-03 0,02927619 ! extracellular structure organization GO:0043062 56 56 3,000 3,593E-03 0,03080232 ! regulation of mast cell proliferation GO:0070666 28 28 2,000 3,745E-03 0,0319553 ! regulation of protein localization GO:0032880 58 57 3,000 3,832E-03 0,032543 ! blood vessel development GO:0001568 95 94 4,000 4,117E-03 0,03480734 ! phosphoinositide metabolic process GO:0030384 29 29 2,000 4,144E-03 0,03486989 ! regulation of epithelial cell proliferation GO:0050678 29 29 2,000 4,144E-03 0,03471139 ! regulation of lymphocyte proliferation GO:0050670 29 29 2,000 4,144E-03 0,03455433 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! regulation of nitric-oxide synthase activity GO:0050999 9 9 1,000 4,339E-03 0,03601842 ! viral genome replication GO:0019079 9 9 1,000 4,339E-03 0,0358569 ! regulation of cell-cell adhesion GO:0022407 9 9 1,000 4,339E-03 0,03569682 ! response to alkaloid GO:0043279 10 9 1,000 4,339E-03 0,03553817 ! response to ethanol GO:0045471 9 9 1,000 4,339E-03 0,03538092 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 1,000 4,339E-03 0,03522506 ! activation of pro-apoptotic gene products GO:0008633 9 9 1,000 4,339E-03 0,03507056 ! pigmentation during development GO:0048066 9 9 1,000 4,339E-03 0,03491742 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 1,000 4,339E-03 0,0347656 GO:0060675|ureteric bud morphogenesis, ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 1,000 4,339E-03 0,0346151 ! prostaglandin metabolic process GO:0006693 9 9 1,000 4,339E-03 0,0344659 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 1,000 4,339E-03 0,03431798 ! regulation of cellular pH GO:0030641 9 9 1,000 4,339E-03 0,03417132 ! histone acetylation GO:0016573 9 9 1,000 4,339E-03 0,03402591 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 1,000 4,339E-03 0,03388173 ! collagen catabolic process GO:0030574 9 9 1,000 4,339E-03 0,03373877 ! vasculature development GO:0001944 97 96 4,000 4,505E-03 0,03488601 ! regulation of ossification GO:0030278 30 30 2,000 4,567E-03 0,03521513 ! regulation of inflammatory response GO:0050727 30 30 2,000 4,567E-03 0,0350684 ! posttranscriptional regulation of gene expression GO:0010608 98 98 4,000 4,918E-03 0,03761242 ! skeletal muscle fiber development GO:0048741 31 31 2,000 5,015E-03 0,03819374 ! B cell activation GO:0042113 31 31 2,000 5,015E-03 0,03803656 ! aging GO:0007568 32 31 2,000 5,015E-03 0,03788068 ! nucleoside metabolic process GO:0009116 31 31 2,000 5,015E-03 0,03772606 ! regulation of intracellular transport GO:0032386 31 31 2,000 5,015E-03 0,0375727 ! anti-apoptosis GO:0006916 100 99 4,000 5,135E-03 0,03831389 ! regulation of lymphocyte activation GO:0051249 62 62 3,000 5,186E-03 0,03853625 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 4,000 5,358E-03 0,0396578 ! hemopoiesis GO:0030097 104 100 4,000 5,358E-03 0,03949917 ! regulation of glucose metabolic process GO:0010906 10 10 1,000 5,384E-03 0,03952951 ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 1,000 5,384E-03 0,03937265 ! inositol metabolic process GO:0006020 10 10 1,000 5,384E-03 0,03921702 ! fat cell differentiation GO:0045444 10 10 1,000 5,384E-03 0,03906263 ! inactivation of MAPK activity GO:0000188 10 10 1,000 5,384E-03 0,03890944 ! regulation of survival gene product expression GO:0045884 10 10 1,000 5,384E-03 0,03875745 ! epidermis morphogenesis GO:0048730 10 10 1,000 5,384E-03 0,03860664 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 1,000 5,384E-03 0,038457 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell structure disassembly during apoptosis GO:0006921 10 10 1,000 5,384E-03 0,03830852 ! regulation of protein binding GO:0043393 11 10 1,000 5,384E-03 0,03816118 ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 1,000 5,384E-03 0,03801497 ! gland morphogenesis GO:0022612 10 10 1,000 5,384E-03 0,03786987 ! lymphocyte homeostasis GO:0002260 10 10 1,000 5,384E-03 0,03772588 ! nerve development GO:0021675 10 10 1,000 5,384E-03 0,03758298 ! positive regulation of neuron apoptosis GO:0043525 10 10 1,000 5,384E-03 0,03744116 ! negative regulation of homeostatic process GO:0032845 10 10 1,000 5,384E-03 0,0373004 ! negative regulation of cell growth GO:0030308 32 32 2,000 5,489E-03 0,03789018 ! muscle fiber development GO:0048747 32 32 2,000 5,489E-03 0,0377488 ! lipid modification GO:0030258 32 32 2,000 5,489E-03 0,03760847 ! negative regulation of cell size GO:0045792 33 33 2,000 5,989E-03 0,04088339 ! regulation of neuron apoptosis GO:0043523 34 33 2,000 5,989E-03 0,04073253 ! regulation of bone remodeling GO:0046850 34 34 2,000 6,516E-03 0,04415102 ! cellular polysaccharide metabolic process GO:0044264 35 34 2,000 6,516E-03 0,04398929 ! secondary metabolic process GO:0019748 34 34 2,000 6,516E-03 0,04382875 ! myeloid leukocyte differentiation GO:0002573 12 11 1,000 6,532E-03 0,04377467 ! endothelial cell migration GO:0043542 11 11 1,000 6,532E-03 0,04361606 ! protein amino acid acetylation GO:0006473 11 11 1,000 6,532E-03 0,0434586 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 1,000 6,532E-03 0,04330228 GO:0032388|positive regulation of intracellular transport, ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 1,000 6,532E-03 0,04314707 ! G1/S transition checkpoint GO:0031575 12 11 1,000 6,532E-03 0,04299298 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 1,000 6,532E-03 0,04283998 ! regulation of monooxygenase activity GO:0032768 11 11 1,000 6,532E-03 0,04268806 ! oogenesis GO:0048477 11 11 1,000 6,532E-03 0,04253722 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 1,000 6,532E-03 0,04238744 GO:0006109|regulation of carbohydrate metabolic process, ! hindbrain development GO:0030902 11 11 1,000 6,532E-03 0,04223871 ! proximal/distal pattern formation GO:0009954 11 11 1,000 6,532E-03 0,04209103 ! negative regulation of lymphocyte activation GO:0051250 11 11 1,000 6,532E-03 0,04194437 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 2,000 7,069E-03 0,04523959 ! regulation of tissue remodeling GO:0034103 35 35 2,000 7,069E-03 0,04508305 ! regionalization GO:0003002 70 69 3,000 7,572E-03 0,0481193 ! regulation of leukocyte activation GO:0002694 69 69 3,000 7,572E-03 0,04795394 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 2,000 7,65E-03 0,04828386 ! heterocycle catabolic process GO:0046700 36 36 2,000 7,65E-03 0,04811907 ! initiation of viral infection GO:0019059 12 12 1,000 7,781E-03 0,04877557 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 1,000 7,781E-03 0,04861023 ! collagen metabolic process GO:0032963 12 12 1,000 7,781E-03 0,04844601 ! acute-phase response GO:0006953 12 12 1,000 7,781E-03 0,04828289 ! regulation of alpha-beta T cell activation GO:0046634 12 12 1,000 7,781E-03 0,04812087 ! renal system process GO:0003014 12 12 1,000 7,781E-03 0,04795993 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 1,000 7,781E-03 0,04780006 ! positive regulation of protein catabolic process GO:0045732 12 12 1,000 7,781E-03 0,04764126 ! heterophilic cell adhesion GO:0007157 12 12 1,000 7,781E-03 0,0474835 ! positive regulation of endocytosis GO:0045807 12 12 1,000 7,781E-03 0,04732679 ! GPI anchor biosynthetic process GO:0006506 12 12 1,000 7,781E-03 0,04717111 GO:0006505|GPI anchor metabolic process, ! deoxyribonucleotide catabolic process GO:0009264 12 12 1,000 7,781E-03 0,04701645 ! male gonad development GO:0008584 12 12 1,000 7,781E-03 0,0468628 ! positive regulation of multicellular organism growth GO:0040018 12 12 1,000 7,781E-03 0,04671016 ! somitogenesis GO:0001756 13 12 1,000 7,781E-03 0,0465585 ! response to drug GO:0042493 37 37 2,000 8,258E-03 0,04925338 ! lung development GO:0030324 38 37 2,000 8,258E-03 0,04909449 ! negative regulation of growth GO:0045926 37 37 2,000 8,258E-03 0,04893663 ! DNA damage response, signal transduction GO:0042770 37 37 2,000 8,258E-03 0,04877979 ! calcium ion homeostasis GO:0055074 71 71 3,000 8,367E-03 0,04926441 GO:0006874|cellular calcium ion homeostasis, ! regulation of cell activation GO:0050865 71 71 3,000 8,367E-03 0,04910752 ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 1,000 9,128E-03 0,05340789 ! keratinization GO:0031424 13 13 1,000 9,128E-03 0,05323887 ! post-embryonic development GO:0009791 14 13 1,000 9,128E-03 0,05307093 ! negative regulation of DNA replication GO:0008156 13 13 1,000 9,128E-03 0,05290404 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 1,000 9,128E-03 0,0527382 ! multicellular organismal catabolic process GO:0044243 13 13 1,000 9,128E-03 0,05257339 ! receptor metabolic process GO:0043112 14 13 1,000 9,128E-03 0,05240961 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 1,000 9,128E-03 0,05224685 ! long-chain fatty acid transport GO:0015909 13 13 1,000 9,128E-03 0,05208509 ! negative regulation of leukocyte activation GO:0002695 13 13 1,000 9,128E-03 0,05192433 ! response to cytokine stimulus GO:0034097 13 13 1,000 9,128E-03 0,05176457 ! purine nucleotide catabolic process GO:0006195 13 13 1,000 9,128E-03 0,05160578 ! blastocyst development GO:0001824 13 13 1,000 9,128E-03 0,05144796 ! positive regulation of DNA replication GO:0045740 14 13 1,000 9,128E-03 0,05129111 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 1,000 9,128E-03 0,05113521 GO:0019692|deoxyribose phosphate metabolic process, ! regeneration GO:0031099 13 13 1,000 9,128E-03 0,05098026 ! response to corticosteroid stimulus GO:0031960 13 13 1,000 9,128E-03 0,05082624 GO:0051384|response to glucocorticoid stimulus, ! actin filament bundle formation GO:0051017 13 13 1,000 9,128E-03 0,05067315 ! ureteric bud development GO:0001657 13 13 1,000 9,128E-03 0,05052097 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 1,000 9,128E-03 0,05036971 ! negative regulation of protein kinase cascade GO:0010741 13 13 1,000 9,128E-03 0,05021936 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 1,000 9,128E-03 0,05006989 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! negative regulation of intracellular transport GO:0032387 13 13 1,000 9,128E-03 0,04992132 ! respiratory tube development GO:0030323 40 39 2,000 9,557E-03 0,05211158 ! nucleotide-excision repair GO:0006289 40 39 2,000 9,557E-03 0,05195786 ! positive regulation of T cell activation GO:0050870 39 39 2,000 9,557E-03 0,05180504 ! respiratory system development GO:0060541 40 39 2,000 9,557E-03 0,05165312 ! lymphocyte differentiation GO:0030098 39 39 2,000 9,557E-03 0,05150209 ! protein oligomerization GO:0051259 39 39 2,000 9,557E-03 0,05135194 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 1,000 0,01057196 0,05663991 ! protein amino acid acylation GO:0043543 14 14 1,000 0,01057196 0,05647574 ! hair cycle GO:0042633 14 14 1,000 0,01057196 0,05631252 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! response to retinoic acid GO:0032526 14 14 1,000 0,01057196 0,05615023 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 1,000 0,01057196 0,05598888 ! D-ribose metabolic process GO:0006014 14 14 1,000 0,01057196 0,05582845 ! response to organic cyclic substance GO:0014070 15 14 1,000 0,01057196 0,05566894 ! DNA modification GO:0006304 14 14 1,000 0,01057196 0,05551034 ! positive regulation of inflammatory response GO:0050729 14 14 1,000 0,01057196 0,05535264 ! cell cycle checkpoint GO:0000075 42 41 2,000 0,01096907 0,05726912 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 2,000 0,01096907 0,05710734 ! cellular metal ion homeostasis GO:0006875 77 77 3,000 0,01107467 0,0574947 ! metal ion homeostasis GO:0055065 78 78 3,000 0,0115748 0,05992237 ! cytosolic calcium ion homeostasis GO:0051480 42 42 2,000 0,0117179 0,06049327 ! protein import into nucleus, translocation GO:0000060 15 15 1,000 0,01210946 0,06234002 ! protein amino acid O-linked glycosylation GO:0006493 15 15 1,000 0,01210946 0,06216637 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 1,000 0,01210946 0,06199368 ! response to vitamin GO:0033273 15 15 1,000 0,01210946 0,06182195 ! ovarian follicle development GO:0001541 15 15 1,000 0,01210946 0,06165118 ! deoxyribonucleotide metabolic process GO:0009262 15 15 1,000 0,01210946 0,06148134 ! chromosome condensation GO:0030261 15 15 1,000 0,01210946 0,06131243 ! regulation of biomineral formation GO:0070167 15 15 1,000 0,01210946 0,06114445 GO:0030500|regulation of bone mineralization, ! leukocyte homeostasis GO:0001776 15 15 1,000 0,01210946 0,06097739 ! glutathione metabolic process GO:0006749 16 15 1,000 0,01210946 0,06081124 ! negative regulation of cell activation GO:0050866 15 15 1,000 0,01210946 0,06064599 ! tube development GO:0035295 83 81 3,000 0,01316185 0,06573794 ! lymphocyte activation GO:0046649 82 81 3,000 0,01316185 0,06556027 ! positive regulation of lymphocyte activation GO:0051251 44 44 2,000 0,0133022 0,06608072 ! spliceosomal snRNP biogenesis GO:0000387 16 16 1,000 0,01373853 0,06806481 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 1,000 0,01373853 0,06788233 ! segmentation GO:0035282 17 16 1,000 0,01373853 0,06770083 ! fatty acid beta-oxidation GO:0006635 16 16 1,000 0,01373853 0,06752029 ! positive regulation of cell development GO:0010720 16 16 1,000 0,01373853 0,06734072 ! lymphocyte proliferation GO:0046651 16 16 1,000 0,01373853 0,0671621 ! pentose metabolic process GO:0019321 16 16 1,000 0,01373853 0,06698442 ! fatty acid transport GO:0015908 16 16 1,000 0,01373853 0,06680768 ! polyol metabolic process GO:0019751 16 16 1,000 0,01373853 0,06663187 ! serine family amino acid metabolic process GO:0009069 16 16 1,000 0,01373853 0,06645698 ! blood vessel morphogenesis GO:0048514 84 83 3,000 0,01429347 0,0689604 ! regulation of fibroblast proliferation GO:0048145 17 17 1,000 0,01545697 0,0743791 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 1,000 0,01545697 0,0741854 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 0,01545697 0,07399271 ! phosphoinositide biosynthetic process GO:0046489 17 17 1,000 0,01545697 0,07380102 ! leukocyte adhesion GO:0007159 17 17 1,000 0,01545697 0,07361032 ! glucose transport GO:0015758 17 17 1,000 0,01545697 0,0734206 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 1,000 0,01545697 0,07323186 ! development of primary male sexual characteristics GO:0046546 17 17 1,000 0,01545697 0,07304409 ! negative regulation of cell development GO:0010721 18 17 1,000 0,01545697 0,07285727 GO:0050768|negative regulation of neurogenesis, ! regulation of oxidoreductase activity GO:0051341 17 17 1,000 0,01545697 0,07267141 ! embryonic organ development GO:0048568 17 17 1,000 0,01545697 0,0724865 ! liver development GO:0001889 17 17 1,000 0,01545697 0,07230252 ! nitrogen compound biosynthetic process GO:0044271 86 85 3,000 0,01548518 0,07225109 ! regulation of catabolic process GO:0009894 48 47 2,000 0,01589748 0,07398752 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 3,000 0,01610387 0,07475926 ! actin filament organization GO:0007015 50 48 2,000 0,01682143 0,07789421 ! glycerophospholipid metabolic process GO:0006650 49 48 2,000 0,01682143 0,07769899 ! regulation of cellular catabolic process GO:0031329 18 18 1,000 0,01726259 0,07953739 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 1,000 0,01726259 0,07933904 ! mononuclear cell proliferation GO:0032943 18 18 1,000 0,01726259 0,07914168 GO:0070661|leukocyte proliferation, ! hexose transport GO:0008645 18 18 1,000 0,01726259 0,0789453 GO:0015749|monosaccharide transport, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 1,000 0,01726259 0,07874989 ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 1,000 0,01726259 0,07855545 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! negative regulation of MAP kinase activity GO:0043407 18 18 1,000 0,01726259 0,07836196 ! gland development GO:0048732 51 49 2,000 0,01777497 0,0804896 ! cell cycle arrest GO:0007050 49 49 2,000 0,01777497 0,08029232 ! positive regulation of cell activation GO:0050867 49 49 2,000 0,01777497 0,08009601 GO:0002696|positive regulation of leukocyte activation, ! chemotaxis GO:0006935 90 89 3,000 0,01805265 0,08114888 GO:0042330|taxis, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 3,000 0,01805265 0,08095144 ! regulation of neurogenesis GO:0050767 51 50 2,000 0,01875817 0,08391093 ! anatomical structure homeostasis GO:0060249 51 50 2,000 0,01875817 0,08370775 ! regulation of defense response GO:0031347 50 50 2,000 0,01875817 0,08350556 ! nitrogen compound catabolic process GO:0044270 51 50 2,000 0,01875817 0,08330434 ! anterior/posterior pattern formation GO:0009952 51 50 2,000 0,01875817 0,08310409 ! negative regulation of DNA metabolic process GO:0051053 19 19 1,000 0,01915325 0,08465095 ! regulation of pH GO:0006885 19 19 1,000 0,01915325 0,08444843 ! positive regulation of T cell proliferation GO:0042102 19 19 1,000 0,01915325 0,08424689 ! multicellular organismal metabolic process GO:0044236 19 19 1,000 0,01915325 0,0840463 ! metanephros development GO:0001656 19 19 1,000 0,01915325 0,08384666 ! peripheral nervous system development GO:0007422 19 19 1,000 0,01915325 0,08364797 ! regulation of cell shape GO:0008360 21 19 1,000 0,01915325 0,08345023 ! response to heat GO:0009408 19 19 1,000 0,01915325 0,08325341 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 3,000 0,01943018 0,0842584 ! interphase of mitotic cell cycle GO:0051329 52 51 2,000 0,01977109 0,08553548 GO:0051325|interphase, ! negative regulation of cell adhesion GO:0007162 21 20 1,000 0,02112684 0,09118683 ! establishment or maintenance of cell polarity GO:0007163 21 20 1,000 0,02112684 0,09097377 ! phagocytosis GO:0006909 21 20 1,000 0,02112684 0,09076171 ! positive regulation of gene-specific transcription GO:0043193 20 20 1,000 0,02112684 0,09055064 ! chromatin remodeling GO:0006338 20 20 1,000 0,02112684 0,09034054 ! lipid oxidation GO:0034440 20 20 1,000 0,02112684 0,09013142 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 1,000 0,02112684 0,08992327 ! negative regulation of neuron apoptosis GO:0043524 21 20 1,000 0,02112684 0,08971607 ! pattern specification process GO:0007389 96 94 3,000 0,02161591 0,09158191 ! regulation of protein transport GO:0051223 53 53 2,000 0,02188625 0,09251459 GO:0070201|regulation of establishment of protein localization, ! negative regulation of multicellular organismal process GO:0051241 55 54 2,000 0,02298855 0,0969517 ! regulation of cell growth GO:0001558 97 96 3,000 0,02315373 0,09742539 ! mammary gland development GO:0030879 23 21 1,000 0,02318129 0,09731919 ! protein amino acid lipidation GO:0006497 21 21 1,000 0,02318129 0,09709801 ! spliceosome assembly GO:0000245 22 21 1,000 0,02318129 0,09687783 ! negative regulation of hydrolase activity GO:0051346 21 21 1,000 0,02318129 0,09665865 ! negative regulation of protein transport GO:0051224 21 21 1,000 0,02318129 0,09644046 ! in utero embryonic development GO:0001701 55 55 2,000 0,02412066 0,10012247 ! reproductive developmental process GO:0003006 56 56 2,000 0,02528259 0,10470967 ! regulation of nervous system development GO:0051960 57 56 2,000 0,02528259 0,1044749 ! positive regulation of transcription factor activity GO:0051091 22 22 1,000 0,02531456 0,10437302 GO:0090047|positive regulation of transcription regulator activity, ! positive regulation of DNA metabolic process GO:0051054 23 22 1,000 0,02531456 0,10414004 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 1,000 0,02531456 0,10390811 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! ovulation cycle process GO:0022602 22 22 1,000 0,02531456 0,1036772 ! male sex differentiation GO:0046661 22 22 1,000 0,02531456 0,10344732 ! neuron migration GO:0001764 22 22 1,000 0,02531456 0,10321845 ! fatty acid catabolic process GO:0009062 23 22 1,000 0,02531456 0,10299059 ! response to other organism GO:0051707 101 100 3,000 0,0264257 0,10727436 ! regulation of binding GO:0051098 60 57 2,000 0,0264743 0,10723547 ! response to hydrogen peroxide GO:0042542 24 23 1,000 0,02752465 0,11124546 ! epithelial cell differentiation GO:0030855 23 23 1,000 0,02752465 0,11100203 ! response to estrogen stimulus GO:0043627 23 23 1,000 0,02752465 0,11075967 ! lipoprotein biosynthetic process GO:0042158 23 23 1,000 0,02752465 0,11051837 ! female gonad development GO:0008585 23 23 1,000 0,02752465 0,11027811 ! monovalent inorganic cation homeostasis GO:0055067 23 23 1,000 0,02752465 0,11003889 ! lipid homeostasis GO:0055088 23 23 1,000 0,02752465 0,10980071 ! calcium-mediated signaling GO:0019722 23 23 1,000 0,02752465 0,10956356 ! carboxylic acid transport GO:0046942 59 59 2,000 0,02894697 0,11497685 GO:0015849|organic acid transport, ! regulation of cell development GO:0060284 60 59 2,000 0,02894697 0,11472959 ! immune effector process GO:0002252 59 59 2,000 0,02894697 0,11448339 ! cellular amino acid biosynthetic process GO:0008652 24 24 1,000 0,02980959 0,11764254 ! nucleotide catabolic process GO:0009166 24 24 1,000 0,02980959 0,11739117 ! ovulation cycle GO:0042698 24 24 1,000 0,02980959 0,11714087 ! epithelial tube morphogenesis GO:0060562 25 24 1,000 0,02980959 0,11689163 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 2,000 0,03022782 0,11827998 ! cellular component disassembly GO:0022411 26 25 1,000 0,03216744 0,12560294 ! development of primary female sexual characteristics GO:0046545 25 25 1,000 0,03216744 0,1253374 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 1,000 0,03216744 0,12507297 ! positive regulation of DNA binding GO:0043388 26 25 1,000 0,03216744 0,12480966 ! heart morphogenesis GO:0003007 25 25 1,000 0,03216744 0,12454745 ! icosanoid metabolic process GO:0006690 25 25 1,000 0,03216744 0,12428635 ! regulation of endocytosis GO:0030100 25 25 1,000 0,03216744 0,12402633 ! negative regulation of immune system process GO:0002683 25 25 1,000 0,03216744 0,12376741 ! morphogenesis of an epithelium GO:0002009 63 62 2,000 0,03287823 0,12623872 GO:0060429|epithelium development, ! positive regulation of binding GO:0051099 27 26 1,000 0,0345963 0,13255922 ! positive regulation of defense response GO:0031349 26 26 1,000 0,0345963 0,1322842 ! induction of apoptosis by intracellular signals GO:0008629 26 26 1,000 0,0345963 0,13201032 ! cellular defense response GO:0006968 26 26 1,000 0,0345963 0,13173757 ! double-strand break repair GO:0006302 27 26 1,000 0,0345963 0,13146595 ! germ cell development GO:0007281 27 26 1,000 0,0345963 0,13119544 ! pigment metabolic process GO:0042440 26 26 1,000 0,0345963 0,13092605 ! maintenance of location in cell GO:0051651 27 26 1,000 0,0345963 0,13065776 ! glycerolipid metabolic process GO:0046486 65 64 2,000 0,03564638 0,13434821 ! regulation of response to external stimulus GO:0032101 65 64 2,000 0,03564638 0,13407403 ! angiogenesis GO:0001525 65 64 2,000 0,03564638 0,13380096 ! chloride transport GO:0006821 27 27 1,000 0,03709431 0,13895288 ! learning or memory GO:0007611 28 27 1,000 0,03709431 0,13867103 ! monocarboxylic acid transport GO:0015718 27 27 1,000 0,03709431 0,13839032 ! peptide metabolic process GO:0006518 29 27 1,000 0,03709431 0,13811074 ! activation of caspase activity GO:0006919 27 27 1,000 0,03709431 0,1378323 ! mesenchymal cell development GO:0014031 29 27 1,000 0,03709431 0,13755497 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! isoprenoid metabolic process GO:0006720 27 27 1,000 0,03709431 0,13727875 ! polysaccharide metabolic process GO:0005976 69 66 2,000 0,03853144 0,14231152 ! negative regulation of protein metabolic process GO:0051248 66 66 2,000 0,03853144 0,1420269 ! carbohydrate transport GO:0008643 28 28 1,000 0,03965963 0,14589361 ! unsaturated fatty acid metabolic process GO:0033559 28 28 1,000 0,03965963 0,14560299 ! keratinocyte differentiation GO:0030216 28 28 1,000 0,03965963 0,14531352 ! histone modification GO:0016570 28 28 1,000 0,03965963 0,1450252 ! developmental growth GO:0048589 28 28 1,000 0,03965963 0,14473802 ! regulation of cell size GO:0008361 68 68 2,000 0,04153248 0,15127344 ! positive regulation of cell cycle GO:0045787 29 29 1,000 0,04229045 0,15373039 ! glycerophospholipid biosynthetic process GO:0046474 30 29 1,000 0,04229045 0,15342777 ! branching morphogenesis of a tube GO:0048754 29 29 1,000 0,04229045 0,15312634 ! covalent chromatin modification GO:0016569 29 29 1,000 0,04229045 0,15282609 ! positive regulation of protein transport GO:0051222 29 29 1,000 0,04229045 0,15252702 ! regulation of translation GO:0006417 69 69 2,000 0,04307615 0,15505733 ! positive regulation of transport GO:0051050 71 70 2,000 0,0446484 0,16040352 ! wound healing GO:0042060 74 70 2,000 0,0446484 0,16009145 ! response to reactive oxygen species GO:0000302 31 30 1,000 0,04498501 0,16098519 ! positive regulation of peptidase activity GO:0010952 30 30 1,000 0,04498501 0,1606732 GO:0043280|positive regulation of caspase activity, ! activation of phospholipase C activity GO:0007202 30 30 1,000 0,04498501 0,16036242 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of response to external stimulus GO:0032103 30 30 1,000 0,04498501 0,16005284 ! response to temperature stimulus GO:0009266 30 30 1,000 0,04498501 0,15974445 ! vesicle organization GO:0016050 30 30 1,000 0,04498501 0,15943725 ! lipoprotein metabolic process GO:0042157 31 31 1,000 0,04774155 0,16888231 ! positive regulation of phospholipase activity GO:0010518 31 31 1,000 0,04774155 0,16855878 ! glycerolipid biosynthetic process GO:0045017 32 31 1,000 0,04774155 0,16823648 ! extracellular matrix organization GO:0030198 31 31 1,000 0,04774155 0,16791542 ! ribonucleoprotein complex assembly GO:0022618 32 31 1,000 0,04774155 0,16759558 ! epidermal cell differentiation GO:0009913 31 31 1,000 0,04774155 0,16727696 ! positive regulation of hydrolase activity GO:0051345 72 72 2,000 0,04787799 0,16743667 ! regulation of phospholipase activity GO:0010517 32 32 1,000 0,05055837 0,17647553 ! regulation of vesicle-mediated transport GO:0060627 33 32 1,000 0,05055837 0,17614193 ! cell maturation GO:0048469 32 32 1,000 0,05055837 0,17580959 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 1,000 0,05055837 0,1754785 ! morphogenesis of a branching structure GO:0001763 32 32 1,000 0,05055837 0,17514865 ! kidney development GO:0001822 32 32 1,000 0,05055837 0,17482004 ! positive regulation of lipase activity GO:0060193 32 32 1,000 0,05055837 0,17449266 ! maintenance of location GO:0051235 33 32 1,000 0,05055837 0,17416651 ! response to oxidative stress GO:0006979 76 75 2,000 0,05293252 0,18200492 ! amino acid transport GO:0006865 33 33 1,000 0,05343379 0,18338636 ! regulation of neuron differentiation GO:0045664 34 33 1,000 0,05343379 0,18304549 ! rRNA transcription GO:0009303 5 5 0,000 0,05543096 0,18953482 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,05543096 0,18918383 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,05543096 0,18883413 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,05543096 0,18848573 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,05543096 0,18813861 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,05543096 0,18779277 ! reproductive cellular process GO:0048610 5 5 0,000 0,05543096 0,18744819 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,05543096 0,18710488 ! prostate gland development GO:0030850 5 5 0,000 0,05543096 0,18676283 ! water transport GO:0006833 5 5 0,000 0,05543096 0,18642202 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,05543096 0,18608245 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,05543096 0,18574412 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,05543096 0,18540702 ! glycerol metabolic process GO:0006071 5 5 0,000 0,05543096 0,18507113 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,05543096 0,18473647 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,05543096 0,18440301 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,05543096 0,18407075 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,05543096 0,18373969 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,05543096 0,18340981 ! CTP metabolic process GO:0046036 5 5 0,000 0,05543096 0,18308112 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,05543096 0,18275361 ! GTP metabolic process GO:0046039 5 5 0,000 0,05543096 0,18242726 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,05543096 0,18210208 ! mRNA stabilization GO:0048255 5 5 0,000 0,05543096 0,18177805 GO:0043489|RNA stabilization, ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,05543096 0,18145518 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,05543096 0,18113345 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,05543096 0,18081286 ! social behavior GO:0035176 5 5 0,000 0,05543096 0,1804934 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,05543096 0,18017507 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,05543096 0,17985786 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 0,05543096 0,17954177 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,05543096 0,17922678 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,05543096 0,1789129 ! erythrocyte maturation GO:0043249 5 5 0,000 0,05543096 0,17860012 ! hippocampus development GO:0021766 6 5 0,000 0,05543096 0,17828842 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,05543096 0,17797781 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,05543096 0,17766829 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,05543096 0,17735984 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,05543096 0,17705245 ! mechanosensory behavior GO:0007638 5 5 0,000 0,05543096 0,17674613 ! heart looping GO:0001947 5 5 0,000 0,05543096 0,17644087 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,05543096 0,17613667 ! response to interferon-gamma GO:0034341 5 5 0,000 0,05543096 0,1758335 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,05543096 0,17553138 ! endocrine pancreas development GO:0031018 5 5 0,000 0,05543096 0,1752303 ! pH reduction GO:0045851 5 5 0,000 0,05543096 0,17493025 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,05543096 0,17463122 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,05543096 0,17433322 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,05543096 0,17403623 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,05543096 0,17374025 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,05543096 0,17344527 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,05543096 0,1731513 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 0,05543096 0,17285832 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,05543096 0,17256633 ! adrenal gland development GO:0030325 5 5 0,000 0,05543096 0,17227532 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,05543096 0,1719853 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,05543096 0,17169625 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,05543096 0,17140816 ! astrocyte differentiation GO:0048708 5 5 0,000 0,05543096 0,17112105 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,05543096 0,17083489 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,05543096 0,17054969 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,05543096 0,17026544 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,05543096 0,16998214 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,05543096 0,16969978 ! microtubule nucleation GO:0007020 5 5 0,000 0,05543096 0,16941835 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,05543096 0,16913786 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,05543096 0,16885829 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,05543096 0,16857965 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,05543096 0,16830192 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,05543096 0,16802511 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,05543096 0,1677492 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,05543096 0,16747421 ! response to ATP GO:0033198 5 5 0,000 0,05543096 0,16720011 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,05543096 0,1669269 ! regulation of appetite GO:0032098 5 5 0,000 0,05543096 0,16665459 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,05543096 0,16638317 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,05543096 0,16611263 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,05543096 0,16584296 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,05543096 0,16557417 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,05543096 0,16530626 ! receptor clustering GO:0043113 5 5 0,000 0,05543096 0,1650392 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,05543096 0,16477301 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 0,05543096 0,16450767 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,05543096 0,16424319 ! retinol metabolic process GO:0042572 5 5 0,000 0,05543096 0,16397956 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,05543096 0,16371677 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,05543096 0,16345483 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,05543096 0,16319372 ! parturition GO:0007567 5 5 0,000 0,05543096 0,16293344 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,05543096 0,16267399 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,05543096 0,16241537 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,05543096 0,16215756 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,05543096 0,16190058 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,05543096 0,16164441 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,05543096 0,16138905 ! oligodendrocyte development GO:0014003 5 5 0,000 0,05543096 0,16113449 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,05543096 0,16088073 ! activated T cell proliferation GO:0050798 5 5 0,000 0,05543096 0,16062778 ! cellular extravasation GO:0045123 5 5 0,000 0,05543096 0,16037561 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,05543096 0,16012424 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,05543096 0,15987366 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,05543096 0,15962385 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,05543096 0,15937483 ! response to amine stimulus GO:0014075 5 5 0,000 0,05543096 0,15912658 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,05543096 0,15887911 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,05543096 0,1586324 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,05543096 0,15838646 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,05543096 0,15814128 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,05543096 0,15789686 ! neuron recognition GO:0008038 5 5 0,000 0,05543096 0,15765319 ! decidualization GO:0046697 5 5 0,000 0,05543096 0,15741027 ! hair follicle maturation GO:0048820 5 5 0,000 0,05543096 0,1571681 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,05543096 0,15692668 ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,05543096 0,15668599 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,05543096 0,15644604 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,05543096 0,15620683 ! postreplication repair GO:0006301 5 5 0,000 0,05543096 0,15596834 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,05543096 0,15573059 GO:0021517|ventral spinal cord development, ! histone methylation GO:0016571 5 5 0,000 0,05543096 0,15549356 ! DNA methylation GO:0006306 5 5 0,000 0,05543096 0,15525724 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,05543096 0,15502165 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,05543096 0,15478677 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,05543096 0,1545526 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,05543096 0,15431913 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,05543096 0,15408637 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,05543096 0,15385432 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,05543096 0,15362296 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,05543096 0,15339229 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,05543096 0,15316232 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,05543096 0,15293303 ! sterol catabolic process GO:0016127 5 5 0,000 0,05543096 0,15270443 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,05543096 0,15247652 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,05543096 0,15224928 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,05543096 0,15202272 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,05543096 0,15179683 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,05543096 0,15157161 ! zymogen activation GO:0031638 5 5 0,000 0,05543096 0,15134706 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,05543096 0,15112317 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,05543096 0,15089995 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,05543096 0,15067738 ! nucleosome positioning GO:0016584 5 5 0,000 0,05543096 0,15045547 ! regulation of isotype switching GO:0045191 5 5 0,000 0,05543096 0,15023421 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,05543096 0,15001361 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,05543096 0,14979364 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,05543096 0,14957433 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,05543096 0,14935565 ! NADPH regeneration GO:0006740 5 5 0,000 0,05543096 0,14913761 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,05543096 0,14892021 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,05543096 0,14870344 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,05543096 0,1484873 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,05543096 0,14827179 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,05543096 0,14805691 ! sarcomere organization GO:0045214 5 5 0,000 0,05543096 0,14784264 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,05543096 0,147629 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,05543096 0,14741597 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,05543096 0,14720355 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,05543096 0,14699175 GO:0045622|regulation of T-helper cell differentiation, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,05543096 0,14678055 ! male genitalia development GO:0030539 5 5 0,000 0,05543096 0,14656997 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,05543096 0,14635998 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,05543096 0,14615059 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,05543096 0,14594181 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,05543096 0,14573362 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,05543096 0,14552602 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,05543096 0,14531901 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,05543096 0,14511259 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,05543096 0,14490676 ! ATP catabolic process GO:0006200 5 5 0,000 0,05543096 0,14470151 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,05543096 0,14449684 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,05543096 0,14429275 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,05543096 0,14408923 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,05543096 0,14388629 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,05543096 0,14368392 ! activation of innate immune response GO:0002218 5 5 0,000 0,05543096 0,14348211 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 0,05543096 0,14328088 ! catecholamine transport GO:0051937 5 5 0,000 0,05543096 0,1430802 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,05543096 0,14288009 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,05543096 0,14268054 ! muscle adaptation GO:0043500 5 5 0,000 0,05543096 0,14248154 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,05543096 0,1422831 ! embryonic heart tube development GO:0035050 5 5 0,000 0,05543096 0,14208521 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,05543096 0,14188787 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,05543096 0,14169108 ! defense response to fungus GO:0050832 5 5 0,000 0,05543096 0,14149483 ! lysogeny GO:0030069 5 5 0,000 0,05543096 0,14129912 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,05543096 0,14110396 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,05543096 0,14090933 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,05543096 0,14071524 ! establishment of cell polarity GO:0030010 5 5 0,000 0,05543096 0,14052169 ! nucleus localization GO:0051647 5 5 0,000 0,05543096 0,14032866 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,05543096 0,14013617 ! regulation of angiogenesis GO:0045765 35 34 1,000 0,05636615 0,14230522 ! response to metal ion GO:0010038 34 34 1,000 0,05636615 0,14211055 ! ear development GO:0043583 34 34 1,000 0,05636615 0,14191641 ! regulation of protein catabolic process GO:0042176 35 34 1,000 0,05636615 0,1417228 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 1,000 0,05636615 0,14152971 ! negative regulation of response to stimulus GO:0048585 34 34 1,000 0,05636615 0,14133716 ! acute inflammatory response GO:0002526 35 35 1,000 0,05935383 0,1486265 ! regulation of cytokine biosynthetic process GO:0042035 35 35 1,000 0,05935383 0,14842483 ! mesoderm development GO:0007498 35 35 1,000 0,05935383 0,14822371 ! multicellular organism reproduction GO:0032504 36 35 1,000 0,05935383 0,14802314 GO:0048609|reproductive process in a multicellular organism, ! regulation of cell morphogenesis GO:0022604 38 35 1,000 0,05935383 0,14782311 ! positive regulation of phosphorylation GO:0042327 35 35 1,000 0,05935383 0,14762362 ! inorganic anion transport GO:0015698 35 35 1,000 0,05935383 0,14742467 ! response to steroid hormone stimulus GO:0048545 35 35 1,000 0,05935383 0,14722625 ! response to inorganic substance GO:0010035 36 36 1,000 0,06239523 0,15456238 ! regulation of mitosis GO:0007088 37 36 1,000 0,06239523 0,15435491 GO:0051783|regulation of nuclear division, ! embryonic limb morphogenesis GO:0030326 36 36 1,000 0,06239523 0,154148 GO:0035113|embryonic appendage morphogenesis, ! positive regulation of phosphorus metabolic process GO:0010562 36 36 1,000 0,06239523 0,15394164 GO:0045937|positive regulation of phosphate metabolic process, ! female pregnancy GO:0007565 37 36 1,000 0,06239523 0,15373584 ! gonad development GO:0008406 36 36 1,000 0,06239523 0,15353059 ! regulation of lipase activity GO:0060191 36 36 1,000 0,06239523 0,15332588 ! MAPKKK cascade GO:0000165 82 81 2,000 0,06377926 0,15651822 ! regulation of transcription factor activity GO:0051090 38 37 1,000 0,06548879 0,16049979 GO:0090046|regulation of transcription regulator activity, ! meiosis GO:0007126 37 37 1,000 0,06548879 0,16028664 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of protein kinase activity GO:0006469 37 37 1,000 0,06548879 0,16007406 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 0,06614753 0,16147006 ! axon extension GO:0048675 7 6 0,000 0,06614753 0,16125648 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,06614753 0,16104345 ! tRNA modification GO:0006400 6 6 0,000 0,06614753 0,160831 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,06614753 0,1606191 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,06614753 0,16040776 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,06614753 0,16019697 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,06614753 0,15998674 ! regulation of S phase GO:0033261 6 6 0,000 0,06614753 0,15977706 ! myotube differentiation GO:0014902 6 6 0,000 0,06614753 0,15956793 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,06614753 0,15935934 ! bone remodeling GO:0046849 6 6 0,000 0,06614753 0,1591513 ! N-glycan processing GO:0006491 6 6 0,000 0,06614753 0,1589438 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 0,06614753 0,15873684 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,06614753 0,15853042 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,06614753 0,15832454 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,06614753 0,15811919 ! RNA methylation GO:0001510 6 6 0,000 0,06614753 0,15791437 ! cartilage condensation GO:0001502 7 6 0,000 0,06614753 0,15771008 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,06614753 0,15750632 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 0,06614753 0,15730309 GO:0050927|positive regulation of positive chemotaxis, ! succinate metabolic process GO:0006105 7 6 0,000 0,06614753 0,15710038 ! artery development GO:0060840 6 6 0,000 0,06614753 0,15689819 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,06614753 0,15669652 ! androgen metabolic process GO:0008209 6 6 0,000 0,06614753 0,15649537 ! estrogen metabolic process GO:0008210 6 6 0,000 0,06614753 0,15629474 ! limbic system development GO:0021761 7 6 0,000 0,06614753 0,15609462 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,06614753 0,15589501 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 0,000 0,06614753 0,15569591 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,06614753 0,15549732 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,06614753 0,15529923 ! pathogenesis GO:0009405 6 6 0,000 0,06614753 0,15510165 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,06614753 0,15490457 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,06614753 0,15470799 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,06614753 0,15451191 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,06614753 0,15431632 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,06614753 0,15412123 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,06614753 0,15392664 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,06614753 0,15373253 ! arginine metabolic process GO:0006525 6 6 0,000 0,06614753 0,15353891 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,06614753 0,15334578 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,06614753 0,15315313 ! glutamate catabolic process GO:0006538 7 6 0,000 0,06614753 0,15296097 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,06614753 0,15276929 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,06614753 0,15257809 GO:0006559|L-phenylalanine catabolic process, ! V(D)J recombination GO:0033151 6 6 0,000 0,06614753 0,15238737 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,06614753 0,15219712 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,06614753 0,15200735 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,06614753 0,15181805 ! regulation of heart rate GO:0002027 6 6 0,000 0,06614753 0,15162922 ! lipid digestion GO:0044241 6 6 0,000 0,06614753 0,15144086 ! asymmetric protein localization GO:0008105 6 6 0,000 0,06614753 0,15125297 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,06614753 0,15106555 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,06614753 0,15087858 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,06614753 0,15069208 ! regulation of vascular permeability GO:0043114 6 6 0,000 0,06614753 0,15050604 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,06614753 0,15032046 ! ruffle organization GO:0031529 6 6 0,000 0,06614753 0,15013534 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,06614753 0,14995067 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,06614753 0,14976646 ! neutral amino acid transport GO:0015804 6 6 0,000 0,06614753 0,14958269 ! L-amino acid transport GO:0015807 6 6 0,000 0,06614753 0,14939938 ! bone mineralization GO:0030282 6 6 0,000 0,06614753 0,14921652 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,06614753 0,1490341 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,06614753 0,14885213 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of bone resorption GO:0045124 6 6 0,000 0,06614753 0,1486706 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,06614753 0,14848952 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,06614753 0,14830887 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,06614753 0,14812867 ! regulation of organ growth GO:0046620 6 6 0,000 0,06614753 0,1479489 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,06614753 0,14776957 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,06614753 0,14759067 ! response to dsRNA GO:0043331 6 6 0,000 0,06614753 0,14741221 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,06614753 0,14723417 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,06614753 0,14705657 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! genitalia development GO:0048806 6 6 0,000 0,06614753 0,14687939 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,06614753 0,14670264 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,06614753 0,14652632 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,06614753 0,14635041 ! multicellular organismal aging GO:0010259 6 6 0,000 0,06614753 0,14617493 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,06614753 0,14599987 ! erythrocyte development GO:0048821 6 6 0,000 0,06614753 0,14582523 ! renal water homeostasis GO:0003091 6 6 0,000 0,06614753 0,14565101 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,06614753 0,1454772 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,06614753 0,14530381 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,06614753 0,14513083 ! ribosome assembly GO:0042255 6 6 0,000 0,06614753 0,14495826 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,06614753 0,1447861 ! diencephalon development GO:0021536 6 6 0,000 0,06614753 0,14461435 ! fucose catabolic process GO:0019317 6 6 0,000 0,06614753 0,144443 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,06614753 0,14427207 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 0,06614753 0,14410153 ! regulation of lipid transport GO:0032368 6 6 0,000 0,06614753 0,1439314 ! regulation of cell division GO:0051302 6 6 0,000 0,06614753 0,14376167 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,06614753 0,14359234 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,06614753 0,14342341 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,06614753 0,14325487 ! neuroblast proliferation GO:0007405 6 6 0,000 0,06614753 0,14308673 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,06614753 0,14291899 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,06614753 0,14275163 ! regulation of glucose transport GO:0010827 6 6 0,000 0,06614753 0,14258467 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,06614753 0,1424181 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,06614753 0,14225192 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,06614753 0,14208612 ! lymph node development GO:0048535 6 6 0,000 0,06614753 0,14192072 ! organic cation transport GO:0015695 6 6 0,000 0,06614753 0,14175569 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,06614753 0,14159105 ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,06614753 0,14142679 ! sperm-egg recognition GO:0035036 7 6 0,000 0,06614753 0,14126291 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,06614753 0,14109942 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,06614753 0,1409363 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,06614753 0,14077355 ! alditol metabolic process GO:0019400 6 6 0,000 0,06614753 0,14061118 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,06614753 0,14044919 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,06614753 0,14028757 ! maternal placenta development GO:0001893 6 6 0,000 0,06614753 0,14012632 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,06614753 0,13996544 ! negative regulation of kinase activity GO:0033673 38 38 1,000 0,06863297 0,14505799 ! chromosome segregation GO:0007059 38 38 1,000 0,06863297 0,14489183 ! urogenital system development GO:0001655 38 38 1,000 0,06863297 0,14472605 ! meiotic cell cycle GO:0051321 38 38 1,000 0,06863297 0,14456065 ! axon guidance GO:0007411 39 38 1,000 0,06863297 0,14439563 ! regulation of homeostatic process GO:0032844 38 38 1,000 0,06863297 0,14423098 ! regulation of cellular localization GO:0060341 86 85 2,000 0,07153839 0,15016543 ! activation of MAPK activity GO:0000187 39 39 1,000 0,07182627 0,15059819 ! nucleoside monophosphate metabolic process GO:0009123 39 39 1,000 0,07182627 0,15042705 ! developmental maturation GO:0021700 39 39 1,000 0,07182627 0,15025631 ! limb development GO:0060173 39 39 1,000 0,07182627 0,15008595 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! organophosphate metabolic process GO:0019637 87 86 2,000 0,07354205 0,15349716 GO:0006644|phospholipid metabolic process, ! DNA catabolic process GO:0006308 41 40 1,000 0,07506718 0,15650318 ! negative regulation of transferase activity GO:0051348 40 40 1,000 0,07506718 0,15632634 ! myeloid cell differentiation GO:0030099 42 40 1,000 0,07506718 0,1561499 ! organelle localization GO:0051640 41 40 1,000 0,07506718 0,15597386 ! respiratory burst GO:0045730 7 7 0,000 0,07674405 0,15927847 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,07674405 0,15909931 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,07674405 0,15892055 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,07674405 0,15874218 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,07674405 0,15856422 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,07674405 0,15838666 ! regulation of chemokine production GO:0032642 7 7 0,000 0,07674405 0,15820949 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,07674405 0,15803272 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,07674405 0,15785635 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,07674405 0,15768036 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,07674405 0,15750477 GO:0043241|protein complex disassembly, ! gene silencing by RNA GO:0031047 7 7 0,000 0,07674405 0,15732957 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,07674405 0,15715476 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,07674405 0,15698034 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,07674405 0,1568063 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,07674405 0,15663265 ! axis specification GO:0009798 7 7 0,000 0,07674405 0,15645939 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,07674405 0,1562865 ! visual behavior GO:0007632 7 7 0,000 0,07674405 0,156114 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,07674405 0,15594188 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,07674405 0,15577014 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,07674405 0,15559877 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,07674405 0,15542779 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,07674405 0,15525717 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,07674405 0,15508694 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,07674405 0,15491707 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,07674405 0,15474758 ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,07674405 0,15457845 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,07674405 0,1544097 ! protein targeting to ER GO:0045047 8 7 0,000 0,07674405 0,15424131 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,07674405 0,1540733 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,07674405 0,15390564 ! endoderm development GO:0007492 7 7 0,000 0,07674405 0,15373835 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,07674405 0,15357143 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,07674405 0,15340486 GO:0006688|glycosphingolipid biosynthetic process, ! response to hexose stimulus GO:0009746 7 7 0,000 0,07674405 0,15323866 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,07674405 0,15307282 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,07674405 0,15290734 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,07674405 0,15274221 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,07674405 0,15257744 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,07674405 0,15241302 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,07674405 0,15224896 ! UV protection GO:0009650 7 7 0,000 0,07674405 0,15208525 ! DNA integration GO:0015074 7 7 0,000 0,07674405 0,1519219 ! myofibril assembly GO:0030239 7 7 0,000 0,07674405 0,15175889 GO:0055002|striated muscle cell development, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,07674405 0,15159623 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,07674405 0,15143392 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,07674405 0,15127196 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,07674405 0,15111035 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,07674405 0,15094908 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,07674405 0,15078815 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,07674405 0,15062757 GO:0019827|stem cell maintenance, ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,07674405 0,15046732 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,07674405 0,15030742 ! axon cargo transport GO:0008088 7 7 0,000 0,07674405 0,15014786 ! eating behavior GO:0042755 7 7 0,000 0,07674405 0,14998864 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,07674405 0,14982975 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,07674405 0,1496712 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,07674405 0,14951299 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,07674405 0,14935511 ! cranial nerve development GO:0021545 7 7 0,000 0,07674405 0,14919756 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,07674405 0,14904034 ! induction of an organ GO:0001759 7 7 0,000 0,07674405 0,14888346 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,07674405 0,1487269 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,07674405 0,14857068 ! autonomic nervous system development GO:0048483 7 7 0,000 0,07674405 0,14841478 ! intracellular lipid transport GO:0032365 7 7 0,000 0,07674405 0,14825921 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,07674405 0,14810396 ! platelet activation GO:0030168 8 7 0,000 0,07674405 0,14794904 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,07674405 0,14779445 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,07674405 0,14764017 ! natural killer cell activation GO:0030101 7 7 0,000 0,07674405 0,14748622 ! NADP metabolic process GO:0006739 7 7 0,000 0,07674405 0,14733259 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,07674405 0,14717928 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,07674405 0,14702628 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,07674405 0,14687361 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,07674405 0,14672125 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,07674405 0,14656921 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,07674405 0,14641748 ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,07674405 0,14626607 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,07674405 0,14611496 ! cell-cell recognition GO:0009988 8 7 0,000 0,07674405 0,14596417 ! hormone catabolic process GO:0042447 7 7 0,000 0,07674405 0,1458137 ! dopamine metabolic process GO:0042417 7 7 0,000 0,07674405 0,14566353 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,07674405 0,14551367 ! oxygen transport GO:0015671 7 7 0,000 0,07674405 0,14536412 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,07674405 0,14521487 ! regulation of mRNA stability GO:0043488 7 7 0,000 0,07674405 0,14506593 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,07674405 0,1449173 ! regulation of axon extension GO:0030516 7 7 0,000 0,07674405 0,14476897 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,07674405 0,14462095 ! adult feeding behavior GO:0008343 7 7 0,000 0,07674405 0,14447322 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,07674405 0,1443258 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,07674405 0,14417868 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,07674405 0,14403186 ! response to cold GO:0009409 7 7 0,000 0,07674405 0,14388534 ! male gamete generation GO:0048232 90 88 2,000 0,07762429 0,14538777 GO:0007283|spermatogenesis, ! regulation of caspase activity GO:0043281 41 41 1,000 0,07835426 0,146606 ! phospholipid biosynthetic process GO:0008654 42 41 1,000 0,07835426 0,14645731 ! regulation of endopeptidase activity GO:0052548 42 42 1,000 0,08168608 0,15253034 ! development of primary sexual characteristics GO:0045137 42 42 1,000 0,08168608 0,15237596 ! protein ubiquitination GO:0016567 43 42 1,000 0,08168608 0,15222189 ! response to protein stimulus GO:0051789 42 42 1,000 0,08168608 0,15206813 ! forebrain development GO:0030900 43 42 1,000 0,08168608 0,15191468 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 1,000 0,08168608 0,15176154 ! brain development GO:0007420 91 90 2,000 0,08180475 0,15182895 ! reproductive structure development GO:0048608 43 43 1,000 0,08506123 0,15771413 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 1,000 0,08506123 0,15755562 ! homeostasis of number of cells GO:0048872 44 43 1,000 0,08506123 0,15739743 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 2,000 0,08608132 0,15912526 ! positive regulation of immune system process GO:0002684 92 92 2,000 0,08608132 0,15896581 ! fatty acid metabolic process GO:0006631 93 92 2,000 0,08608132 0,15880669 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,08722186 0,16074988 ! positive regulation of translation GO:0045727 8 8 0,000 0,08722186 0,16058929 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,08722186 0,16042902 ! superoxide anion generation GO:0042554 8 8 0,000 0,08722186 0,16026908 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,08722186 0,16010945 ! cGMP metabolic process GO:0046068 8 8 0,000 0,08722186 0,15995013 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,08722186 0,15979114 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,08722186 0,15963246 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,08722186 0,15947409 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,08722186 0,15931604 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,08722186 0,1591583 ! zinc ion transport GO:0006829 8 8 0,000 0,08722186 0,15900087 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,08722186 0,15884376 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,08722186 0,15868695 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,08722186 0,15853046 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,08722186 0,15837427 ! lipid localization GO:0010876 8 8 0,000 0,08722186 0,15821839 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,08722186 0,15806281 ! response to cAMP GO:0051591 8 8 0,000 0,08722186 0,15790755 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,08722186 0,15775258 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,08722186 0,15759792 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,08722186 0,15744357 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,08722186 0,15728951 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,08722186 0,15713576 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,08722186 0,15698231 ! sensory perception of taste GO:0050909 8 8 0,000 0,08722186 0,15682915 ! organelle fusion GO:0048284 8 8 0,000 0,08722186 0,1566763 ! pancreas development GO:0031016 8 8 0,000 0,08722186 0,15652374 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,08722186 0,15637148 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,08722186 0,15621952 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,08722186 0,15606785 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,08722186 0,15591647 ! sperm motility GO:0030317 8 8 0,000 0,08722186 0,15576539 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,08722186 0,1556146 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,08722186 0,1554641 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,08722186 0,1553139 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,08722186 0,15516398 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,08722186 0,15501435 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,08722186 0,15486501 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,08722186 0,15471596 ! Golgi organization GO:0007030 8 8 0,000 0,08722186 0,15456719 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,08722186 0,15441872 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,08722186 0,15427052 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 0,08722186 0,15412261 ! fructose metabolic process GO:0006000 8 8 0,000 0,08722186 0,15397498 ! mannose metabolic process GO:0006013 9 8 0,000 0,08722186 0,15382764 ! NAD metabolic process GO:0019674 8 8 0,000 0,08722186 0,15368058 ! plasma membrane fusion GO:0045026 8 8 0,000 0,08722186 0,15353379 ! response to fungus GO:0009620 8 8 0,000 0,08722186 0,15338729 ! stem cell differentiation GO:0048863 8 8 0,000 0,08722186 0,15324107 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,08722186 0,15309513 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,08722186 0,15294946 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,08722186 0,15280407 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,08722186 0,15265896 ! regulation of vasodilation GO:0042312 8 8 0,000 0,08722186 0,15251412 ! vasoconstriction GO:0042310 8 8 0,000 0,08722186 0,15236956 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,08722186 0,15222527 ! muscle cell development GO:0055001 8 8 0,000 0,08722186 0,15208125 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,08722186 0,15193751 ! sensory perception of pain GO:0019233 8 8 0,000 0,08722186 0,15179403 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,08722186 0,15165083 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,08722186 0,1515079 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,08722186 0,15136524 ! chromatin silencing GO:0006342 8 8 0,000 0,08722186 0,15122284 ! tissue regeneration GO:0042246 8 8 0,000 0,08722186 0,15108072 ! salivary gland development GO:0007431 8 8 0,000 0,08722186 0,15093886 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,08722186 0,15079726 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,08722186 0,15065594 ! water homeostasis GO:0030104 8 8 0,000 0,08722186 0,15051487 ! cofactor transport GO:0051181 8 8 0,000 0,08722186 0,15037407 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,08722186 0,15023354 ! acid secretion GO:0046717 8 8 0,000 0,08722186 0,15009326 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 0,08722186 0,14995325 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,08722186 0,1498135 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,08722186 0,14967401 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,08722186 0,14953477 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,08722186 0,1493958 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,08722186 0,14925709 ! regulation of RNA stability GO:0043487 8 8 0,000 0,08722186 0,14911863 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,08722186 0,14898043 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,08722186 0,14884248 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,08722186 0,14870479 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,08722186 0,14856736 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,08722186 0,14843018 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,08722186 0,14829325 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,08722186 0,14815657 ! developmental induction GO:0031128 8 8 0,000 0,08722186 0,14802015 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,08722186 0,14788398 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,08722186 0,14774805 ! actin filament polymerization GO:0030041 9 8 0,000 0,08722186 0,14761238 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 0,08722186 0,14747696 ! peptide hormone processing GO:0016486 8 8 0,000 0,08722186 0,14734178 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,08722186 0,14720685 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,08722186 0,14707217 ! tissue morphogenesis GO:0048729 94 93 2,000 0,08825499 0,1486782 ! humoral immune response GO:0006959 44 44 1,000 0,08847833 0,14891831 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 1,000 0,08847833 0,14878244 ! protein import into nucleus GO:0006606 44 44 1,000 0,08847833 0,14864681 ! regulation of response to stress GO:0080134 97 94 2,000 0,09045188 0,15182406 ! epidermis development GO:0008544 94 94 2,000 0,09045188 0,15168592 ! amine biosynthetic process GO:0009309 46 45 1,000 0,09193602 0,15403462 ! regulation of DNA binding GO:0051101 47 45 1,000 0,09193602 0,15389471 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 1,000 0,09193602 0,15375506 ! nuclear import GO:0051170 45 45 1,000 0,09193602 0,15361567 ! Wnt receptor signaling pathway GO:0016055 46 45 1,000 0,09193602 0,15347652 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 1,000 0,09543297 0,1591701 ! tube morphogenesis GO:0035239 47 46 1,000 0,09543297 0,15902619 ! regulation of peptidase activity GO:0052547 46 46 1,000 0,09543297 0,15888253 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 1,000 0,09543297 0,15873914 ! positive regulation of ligase activity GO:0051351 47 46 1,000 0,09543297 0,158596 ! lactation GO:0007595 10 9 0,000 0,09758226 0,16202172 ! embryonic pattern specification GO:0009880 10 9 0,000 0,09758226 0,16187588 ! positive regulation of cell size GO:0045793 9 9 0,000 0,09758226 0,16173031 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,09758226 0,161585 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,09758226 0,16143995 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,09758226 0,16129516 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,09758226 0,16115063 ! negative regulation of cell cycle process GO:0010948 9 9 0,000 0,09758226 0,16100636 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,09758226 0,16086235 ! copper ion transport GO:0006825 9 9 0,000 0,09758226 0,16071859 ! lipid phosphorylation GO:0046834 9 9 0,000 0,09758226 0,1605751 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,09758226 0,16043185 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,09758226 0,16028887 ! RNA polyadenylation GO:0043631 9 9 0,000 0,09758226 0,16014613 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,09758226 0,16000365 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,09758226 0,15986143 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,09758226 0,15971946 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,09758226 0,15957773 ! phospholipid efflux GO:0033700 9 9 0,000 0,09758226 0,15943627 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,09758226 0,15929505 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,09758226 0,15915408 GO:0042107|cytokine metabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 9 9 0,000 0,09758226 0,15901336 ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,09758226 0,15887289 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,09758226 0,15873266 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,09758226 0,15859269 ! methionine metabolic process GO:0006555 9 9 0,000 0,09758226 0,15845296 ! glutamine metabolic process GO:0006541 9 9 0,000 0,09758226 0,15831347 ! cerebral cortex development GO:0021987 9 9 0,000 0,09758226 0,15817424 ! response to osmotic stress GO:0006970 9 9 0,000 0,09758226 0,15803524 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,09758226 0,15789649 ! central nervous system neuron development GO:0021954 10 9 0,000 0,09758226 0,15775799 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,09758226 0,15761973 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,09758226 0,1574817 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,09758226 0,15734393 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,09758226 0,15720639 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,09758226 0,15706909 ! L-glutamate transport GO:0015813 9 9 0,000 0,09758226 0,15693203 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,09758226 0,15679521 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,09758226 0,15665863 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,09758226 0,15652229 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,09758226 0,15638618 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,09758226 0,15625031 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,09758226 0,15611468 ! positive regulation of protein import into nucleus GO:0042307 9 9 0,000 0,09758226 0,15597928 ! DNA replication initiation GO:0006270 9 9 0,000 0,09758226 0,15584411 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,09758226 0,15570918 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,09758226 0,15557449 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,09758226 0,15544002 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,09758226 0,15530579 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,09758226 0,15517179 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,09758226 0,15503802 ! regulation of leukocyte migration GO:0002685 9 9 0,000 0,09758226 0,15490448 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,09758226 0,15477118 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,09758226 0,1546381 ! purine base metabolic process GO:0006144 9 9 0,000 0,09758226 0,15450525 ! gas transport GO:0015669 9 9 0,000 0,09758226 0,15437262 ! cholesterol efflux GO:0033344 9 9 0,000 0,09758226 0,15424023 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,09758226 0,15410806 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,09758226 0,15397612 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,09758226 0,1538444 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,09758226 0,15371291 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 0,000 0,09758226 0,15358165 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,09758226 0,1534506 ! actin filament-based movement GO:0030048 9 9 0,000 0,09758226 0,15331978 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,09758226 0,15318919 ! regulation of blood pressure GO:0008217 48 47 1,000 0,09896788 0,15523217 ! sex differentiation GO:0007548 47 47 1,000 0,09896788 0,15510017 ! amine transport GO:0015837 47 47 1,000 0,09896788 0,1549684 ! rhythmic process GO:0048511 47 47 1,000 0,09896788 0,15483685 ! endocytosis GO:0006897 99 98 2,000 0,09946617 0,15548444 GO:0010324|membrane invagination, ! ectoderm development GO:0007398 99 99 2,000 0,10177502 0,15895879 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 1,000 0,10253947 0,16001713 ! regulation of cell cycle process GO:0010564 50 48 1,000 0,10253947 0,15988176 ! protein localization in nucleus GO:0034504 48 48 1,000 0,10253947 0,15974661 ! cellular lipid catabolic process GO:0044242 50 49 1,000 0,10614647 0,1652263 ! regulation of ligase activity GO:0051340 50 49 1,000 0,10614647 0,16508687 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,10782656 0,16755848 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,10782656 0,16741731 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,10782656 0,16727639 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,10782656 0,1671357 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,10782656 0,16699525 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,10782656 0,16685504 ! neuron maturation GO:0042551 10 10 0,000 0,10782656 0,16671506 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,10782656 0,16657532 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,10782656 0,16643581 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,10782656 0,16629653 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,10782656 0,16615748 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,10782656 0,16601867 ! hormone secretion GO:0046879 10 10 0,000 0,10782656 0,16588009 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,10782656 0,16574174 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,10782656 0,16560363 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! cAMP metabolic process GO:0046058 10 10 0,000 0,10782656 0,16546574 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,10782656 0,16532808 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,10782656 0,16519065 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,10782656 0,16505345 ! glial cell development GO:0021782 10 10 0,000 0,10782656 0,16491647 ! phototransduction GO:0007602 11 10 0,000 0,10782656 0,16477973 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,10782656 0,16464321 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,10782656 0,16450691 ! myoblast differentiation GO:0045445 10 10 0,000 0,10782656 0,16437084 ! centrosome cycle GO:0007098 10 10 0,000 0,10782656 0,164235 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,10782656 0,16409938 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,10782656 0,16396399 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,10782656 0,16382881 ! protein polyubiquitination GO:0000209 10 10 0,000 0,10782656 0,16369386 ! glutamate metabolic process GO:0006536 11 10 0,000 0,10782656 0,16355914 ! plasma membrane organization GO:0007009 10 10 0,000 0,10782656 0,16342463 ! lysosomal transport GO:0007041 10 10 0,000 0,10782656 0,16329035 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,10782656 0,16315628 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,10782656 0,16302244 ! vesicle coating GO:0006901 10 10 0,000 0,10782656 0,16288881 ! exocrine system development GO:0035272 10 10 0,000 0,10782656 0,16275541 ! embryo implantation GO:0007566 11 10 0,000 0,10782656 0,16262222 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,10782656 0,16248925 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,10782656 0,1623565 GO:0070585|protein localization in mitochondrion, ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,10782656 0,16222396 ! protein export from nucleus GO:0006611 10 10 0,000 0,10782656 0,16209164 ! negative regulation of immune response GO:0050777 10 10 0,000 0,10782656 0,16195954 ! cytolysis GO:0019835 10 10 0,000 0,10782656 0,16182765 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,10782656 0,16169597 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,10782656 0,16156451 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,10782656 0,16143327 ! histone deacetylation GO:0016575 10 10 0,000 0,10782656 0,16130223 ! mRNA splice site selection GO:0006376 11 10 0,000 0,10782656 0,16117141 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,10782656 0,1610408 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,10782656 0,16091041 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,10782656 0,16078022 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,10782656 0,16065024 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,10782656 0,16052048 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,10782656 0,16039092 ! regulation of epidermis development GO:0045682 10 10 0,000 0,10782656 0,16026157 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,10782656 0,16013243 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,10782656 0,1600035 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,10782656 0,15987478 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,10782656 0,15974626 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,10782656 0,15961795 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 0,10782656 0,15948985 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,10782656 0,15936195 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,10782656 0,15923426 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,10782656 0,15910677 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,10782656 0,15897948 ! protein stabilization GO:0050821 10 10 0,000 0,10782656 0,1588524 ! negative regulation of transport GO:0051051 51 50 1,000 0,10978765 0,16161232 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 1,000 0,10978765 0,16148334 ! protein modification by small protein conjugation GO:0032446 52 51 1,000 0,11346179 0,16675445 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 1,000 0,11716771 0,17206382 ! protein secretion GO:0009306 11 11 0,000 0,11795604 0,17308359 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,11795604 0,17294589 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,11795604 0,17280841 ! negative regulation of defense response GO:0031348 11 11 0,000 0,11795604 0,17267115 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,11795604 0,17253411 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,11795604 0,17239729 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,11795604 0,17226068 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,11795604 0,17212429 ! skin development GO:0043588 11 11 0,000 0,11795604 0,17198812 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,11795604 0,17185216 ! signal complex assembly GO:0007172 11 11 0,000 0,11795604 0,17171642 ! microtubule-based transport GO:0010970 11 11 0,000 0,11795604 0,17158089 ! peroxisomal transport GO:0043574 11 11 0,000 0,11795604 0,17144557 ! protein amino acid methylation GO:0006479 11 11 0,000 0,11795604 0,17131047 GO:0008213|protein amino acid alkylation, ! heart contraction GO:0060047 11 11 0,000 0,11795604 0,17117558 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,11795604 0,1710409 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,11795604 0,17090643 ! T cell proliferation GO:0042098 11 11 0,000 0,11795604 0,17077218 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,11795604 0,17063813 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,11795604 0,1705043 ! spinal cord development GO:0021510 11 11 0,000 0,11795604 0,17037068 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,11795604 0,17023726 ! smooth muscle contraction GO:0006939 11 11 0,000 0,11795604 0,17010406 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,11795604 0,16997106 ! digestive system process GO:0022600 11 11 0,000 0,11795604 0,16983827 ! mitotic spindle organization GO:0007052 11 11 0,000 0,11795604 0,16970569 ! fucose metabolic process GO:0006004 11 11 0,000 0,11795604 0,16957331 ! membrane budding GO:0006900 11 11 0,000 0,11795604 0,16944114 ! monoamine transport GO:0015844 11 11 0,000 0,11795604 0,16930918 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,11795604 0,16917742 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,11795604 0,16904587 ! body fluid secretion GO:0007589 11 11 0,000 0,11795604 0,16891452 ! intermediate filament-based process GO:0045103 11 11 0,000 0,11795604 0,16878337 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,11795604 0,16865243 GO:0060415|muscle tissue morphogenesis, ! membrane depolarization GO:0051899 11 11 0,000 0,11795604 0,16852169 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,11795604 0,16839116 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,11795604 0,16826082 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,11795604 0,16813069 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,11795604 0,16800076 ! vitamin transport GO:0051180 11 11 0,000 0,11795604 0,16787103 ! muscle maintenance GO:0046716 12 11 0,000 0,11795604 0,1677415 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,11795604 0,16761217 ! steroid catabolic process GO:0006706 11 11 0,000 0,11795604 0,16748304 ! endocrine process GO:0050886 11 11 0,000 0,11795604 0,16735411 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,11795604 0,16722537 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,11795604 0,16709684 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,11795604 0,1669685 ! carbohydrate biosynthetic process GO:0016051 53 53 1,000 0,12090424 0,17101037 ! sulfur metabolic process GO:0006790 55 54 1,000 0,12467023 0,17620186 ! translational initiation GO:0006413 12 12 0,000 0,12797197 0,18072977 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,12797197 0,18059138 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,12797197 0,18045321 ! iron ion transport GO:0006826 13 12 0,000 0,12797197 0,18031525 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,12797197 0,1801775 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,12797197 0,18003996 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,12797197 0,17990263 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,12797197 0,17976551 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,12797197 0,17962859 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,12797197 0,17949189 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,12797197 0,17935539 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,12797197 0,17921911 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,12797197 0,17908302 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,12797197 0,17894715 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,12797197 0,17881148 ! actomyosin structure organization GO:0031032 12 12 0,000 0,12797197 0,17867602 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,12797197 0,17854076 GO:0051297|centrosome organization, ! retinoid metabolic process GO:0001523 12 12 0,000 0,12797197 0,17840571 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,12797197 0,17827086 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,12797197 0,17813621 ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,12797197 0,17800177 ! vacuolar transport GO:0007034 12 12 0,000 0,12797197 0,17786753 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,12797197 0,17773349 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,12797197 0,17759966 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,12797197 0,17746602 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,12797197 0,17733259 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,12797197 0,17719936 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,12797197 0,17706632 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,12797197 0,17693349 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,12797197 0,17680086 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,12797197 0,17666842 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,12797197 0,17653619 ! pallium development GO:0021543 13 12 0,000 0,12797197 0,17640415 ! cell fate determination GO:0001709 12 12 0,000 0,12797197 0,1762723 ! regulation of chromosome organization GO:0033044 12 12 0,000 0,12797197 0,17614066 ! G1 phase GO:0051318 13 12 0,000 0,12797197 0,17600921 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,12797197 0,17587796 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,12797197 0,1757469 ! detection of light stimulus GO:0009583 13 12 0,000 0,12797197 0,17561604 ! synaptogenesis GO:0007416 12 12 0,000 0,12797197 0,17548537 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,12797197 0,1753549 ! hormone transport GO:0009914 12 12 0,000 0,12797197 0,17522462 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,12797197 0,17509454 ! heme biosynthetic process GO:0006783 12 12 0,000 0,12797197 0,17496465 ! spermatid differentiation GO:0048515 13 12 0,000 0,12797197 0,17483495 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,12797197 0,17470544 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,12797197 0,17457612 ! neural tube closure GO:0001843 13 12 0,000 0,12797197 0,174447 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 0,000 0,12797197 0,17431807 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,12797197 0,17418932 ! protein modification by small protein conjugation or removal GO:0070647 56 55 1,000 0,12846455 0,17473075 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 0,000 0,13787561 0,18739288 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,13787561 0,18725479 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,13787561 0,1871169 ! phenol metabolic process GO:0018958 13 13 0,000 0,13787561 0,18697921 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,13787561 0,18684173 ! gluconeogenesis GO:0006094 13 13 0,000 0,13787561 0,18670444 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,13787561 0,18656736 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,13787561 0,18643048 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,13787561 0,1862938 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,13787561 0,18615733 ! patterning of blood vessels GO:0001569 13 13 0,000 0,13787561 0,18602105 ! vasculogenesis GO:0001570 13 13 0,000 0,13787561 0,18588497 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,13787561 0,18574909 ! regulation of innate immune response GO:0045088 13 13 0,000 0,13787561 0,1856134 ! autophagy GO:0006914 13 13 0,000 0,13787561 0,18547792 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,13787561 0,18534263 ! regulation of endothelial cell migration GO:0010594 13 13 0,000 0,13787561 0,18520754 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,13787561 0,18507265 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,13787561 0,18493795 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,13787561 0,18480345 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,13787561 0,18466915 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,13787561 0,18453504 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,13787561 0,18440112 ! vasodilation GO:0042311 14 13 0,000 0,13787561 0,1842674 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,13787561 0,18413388 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,13787561 0,18400054 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,13787561 0,1838674 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 0,13787561 0,18373445 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 0,000 0,13787561 0,1836017 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,13787561 0,18346913 ! immunoglobulin production GO:0002377 13 13 0,000 0,13787561 0,18333676 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,13787561 0,18320458 ! cell-cell junction organization GO:0045216 13 13 0,000 0,13787561 0,18307259 ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,13787561 0,18294078 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,13787561 0,18280917 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,13787561 0,18267775 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,13787561 0,18254651 GO:0019370|leukotriene biosynthetic process, ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,13787561 0,18241547 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,13787561 0,18228461 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,13787561 0,18215394 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,13787561 0,18202346 ! telomere organization GO:0032200 13 13 0,000 0,13787561 0,18189316 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,13787561 0,18176305 ! regulation of amine transport GO:0051952 13 13 0,000 0,13787561 0,18163313 ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,13787561 0,18150339 ! innate immune response GO:0045087 58 58 1,000 0,14000659 0,18417712 ! protein localization in organelle GO:0033365 59 59 1,000 0,14390342 0,18916834 ! neuron fate commitment GO:0048663 14 14 0,000 0,1476682 0,19397897 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,1476682 0,1938408 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,1476682 0,19370284 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,1476682 0,19356507 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,1476682 0,1934275 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,1476682 0,19329012 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,1476682 0,19315294 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,1476682 0,19301595 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,1476682 0,19287916 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,1476682 0,19274256 ! vesicle docking GO:0048278 14 14 0,000 0,1476682 0,19260615 ! superoxide metabolic process GO:0006801 15 14 0,000 0,1476682 0,19246994 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,1476682 0,19233391 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,1476682 0,19219809 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,1476682 0,19206245 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,1476682 0,191927 ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,1476682 0,19179175 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,1476682 0,19165668 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! lysosome organization GO:0007040 14 14 0,000 0,1476682 0,19152181 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,1476682 0,19138712 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,1476682 0,19125263 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,1476682 0,19111832 ! primary neural tube formation GO:0014020 15 14 0,000 0,1476682 0,1909842 ! peptide cross-linking GO:0018149 14 14 0,000 0,1476682 0,19085027 ! regulation of behavior GO:0050795 14 14 0,000 0,1476682 0,19071653 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,1476682 0,19058298 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,1476682 0,19044961 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,1476682 0,19031643 ! formation of primary germ layer GO:0001704 14 14 0,000 0,1476682 0,19018343 GO:0001707|mesoderm formation, ! collagen fibril organization GO:0030199 14 14 0,000 0,1476682 0,19005062 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,1476682 0,189918 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,1476682 0,18978556 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,1476682 0,1896533 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,1476682 0,18952123 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,1476682 0,18938934 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,1476682 0,18925764 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,1476682 0,18912612 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,1476682 0,18899478 ! proteasomal protein catabolic process GO:0010498 62 61 1,000 0,15176514 0,1941035 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! regulation of protein amino acid phosphorylation GO:0001932 62 61 1,000 0,15176514 0,19396889 ! carboxylic acid catabolic process GO:0046395 63 61 1,000 0,15176514 0,19383447 GO:0016054|organic acid catabolic process, ! lipid transport GO:0006869 62 62 1,000 0,15572803 0,19875815 ! regulation of cellular component biogenesis GO:0044087 63 62 1,000 0,15572803 0,1986206 ! protein import GO:0017038 62 62 1,000 0,15572803 0,19848324 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,15735097 0,20041315 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,15735097 0,20027474 ! positive regulation of ossification GO:0045778 15 15 0,000 0,15735097 0,20013653 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,15735097 0,1999985 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,15735097 0,19986067 ! regulation of transcription factor import into nucleus GO:0042990 15 15 0,000 0,15735097 0,19972302 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,15735097 0,19958557 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,15735097 0,1994483 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,15735097 0,19931122 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,15735097 0,19917433 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,15735097 0,19903763 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,15735097 0,19890112 ! heme metabolic process GO:0042168 15 15 0,000 0,15735097 0,19876479 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,15735097 0,19862865 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,15735097 0,1984927 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,15735097 0,19835693 ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,15735097 0,19822135 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,15735097 0,19808595 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,15735097 0,19795074 ! phospholipid transport GO:0015914 15 15 0,000 0,15735097 0,19781571 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,15735097 0,19768086 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,15735097 0,1975462 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,15735097 0,19741173 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,15735097 0,19727743 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,15735097 0,19714332 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,15735097 0,19700939 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,15735097 0,19687565 ! protein homooligomerization GO:0051260 15 15 0,000 0,15735097 0,19674208 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,15735097 0,1966087 ! negative regulation of cellular component organization GO:0051129 65 63 1,000 0,159711 0,19942233 ! glucose metabolic process GO:0006006 63 63 1,000 0,159711 0,19928732 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 1,000 0,159711 0,19915248 ! positive regulation of protein metabolic process GO:0051247 64 64 1,000 0,16371308 0,20400487 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,16692513 0,2078669 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,16692513 0,20772654 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,16692513 0,20758638 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,16692513 0,2074464 ! learning GO:0007612 16 16 0,000 0,16692513 0,20730661 ! circadian rhythm GO:0007623 16 16 0,000 0,16692513 0,20716701 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,16692513 0,2070276 ! positive regulation of mitosis GO:0045840 16 16 0,000 0,16692513 0,20688837 GO:0051785|positive regulation of nuclear division, ! vacuole organization GO:0007033 16 16 0,000 0,16692513 0,20674933 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,16692513 0,20661048 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,16692513 0,20647182 ! vesicle targeting GO:0006903 17 16 0,000 0,16692513 0,20633334 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,16692513 0,20619505 ! iron ion homeostasis GO:0055072 16 16 0,000 0,16692513 0,20605694 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,16692513 0,20591902 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,16692513 0,20578128 ! cell fate specification GO:0001708 16 16 0,000 0,16692513 0,20564372 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,16692513 0,20550635 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,16692513 0,20536917 ! cofactor catabolic process GO:0051187 16 16 0,000 0,16692513 0,20523216 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,16692513 0,20509534 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,16692513 0,2049587 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,16692513 0,20482224 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,16692513 0,20468597 GO:0001841|neural tube formation, ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,16692513 0,20454987 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,16692513 0,20441396 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,16692513 0,20427823 ! regulation of coagulation GO:0050818 17 16 0,000 0,16692513 0,20414267 ! anion transport GO:0006820 65 65 1,000 0,16773336 0,20499508 ! positive regulation of cellular component organization GO:0051130 65 65 1,000 0,16773336 0,20485923 ! protein amino acid glycosylation GO:0006486 66 66 1,000 0,17177092 0,20965152 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 1,000 0,17177092 0,20951277 ! DNA packaging GO:0006323 66 66 1,000 0,17177092 0,20937421 ! Golgi vesicle transport GO:0048193 67 67 1,000 0,17582487 0,21417398 ! negative regulation of cell differentiation GO:0045596 68 67 1,000 0,17582487 0,21403252 ! Ras protein signal transduction GO:0007265 69 67 1,000 0,17582487 0,21389124 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,17639189 0,21443948 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,17639189 0,21429812 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,17639189 0,21415695 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,17639189 0,21401596 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,17639189 0,21387516 ! sensory perception of smell GO:0007608 17 17 0,000 0,17639189 0,21373455 ! tissue remodeling GO:0048771 17 17 0,000 0,17639189 0,21359412 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,17639189 0,21345387 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,17639189 0,21331381 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,17639189 0,21317393 ! neural crest cell development GO:0014032 19 17 0,000 0,17639189 0,21303424 GO:0014033|neural crest cell differentiation, ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,17639189 0,21289473 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,17639189 0,2127554 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,17639189 0,21261625 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,17639189 0,21247729 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,17639189 0,2123385 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,17639189 0,2121999 ! adult locomotory behavior GO:0008344 17 17 0,000 0,17639189 0,21206148 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,17639189 0,21192324 ! gene silencing GO:0016458 17 17 0,000 0,17639189 0,21178518 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 1,000 0,17989433 0,21584978 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,18575243 0,22273373 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,18575243 0,22258891 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,18575243 0,22244427 ! meiosis I GO:0007127 18 18 0,000 0,18575243 0,22229983 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,18575243 0,22215557 ! membrane docking GO:0022406 18 18 0,000 0,18575243 0,2220115 ! response to calcium ion GO:0051592 18 18 0,000 0,18575243 0,22186762 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,18575243 0,22172392 ! cholesterol homeostasis GO:0042632 18 18 0,000 0,18575243 0,22158041 GO:0055092|sterol homeostasis, ! striated muscle contraction GO:0006941 18 18 0,000 0,18575243 0,22143709 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,18575243 0,22129395 GO:0006639|acylglycerol metabolic process, ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,18575243 0,22115099 ! ceramide metabolic process GO:0006672 18 18 0,000 0,18575243 0,22100822 GO:0046519|sphingoid metabolic process, ! telencephalon development GO:0021537 19 18 0,000 0,18575243 0,22086564 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,18575243 0,22072323 ! BMP signaling pathway GO:0030509 18 18 0,000 0,18575243 0,22058102 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,18575243 0,22043898 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,18575243 0,22029713 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,18575243 0,22015546 ! growth GO:0040007 70 70 1,000 0,1880764 0,22276659 ! carboxylic acid biosynthetic process GO:0046394 70 70 1,000 0,1880764 0,22262351 GO:0016053|organic acid biosynthetic process, ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,19500794 0,23068013 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,19500794 0,23053216 GO:0006956|complement activation, ! glial cell differentiation GO:0010001 19 19 0,000 0,19500794 0,23038439 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,19500794 0,2302368 ! feeding behavior GO:0007631 19 19 0,000 0,19500794 0,2300894 ! regulation of endothelial cell proliferation GO:0001936 19 19 0,000 0,19500794 0,22994219 ! peroxisome organization GO:0007031 19 19 0,000 0,19500794 0,22979517 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,19500794 0,22964833 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,19500794 0,22950169 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,19500794 0,22935523 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,19500794 0,22920896 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,19500794 0,22906287 ! dorsal/ventral pattern formation GO:0009953 19 19 0,000 0,19500794 0,22891697 ! eye morphogenesis GO:0048592 19 19 0,000 0,19500794 0,22877125 ! vesicle localization GO:0051648 20 19 0,000 0,19500794 0,22862573 ! sensory organ development GO:0007423 72 72 1,000 0,19631046 0,23000647 ! regulation of cytokine production GO:0001817 72 72 1,000 0,19631046 0,22986034 ! negative regulation of binding GO:0051100 21 20 0,000 0,20415958 0,23889912 ! organic ether metabolic process GO:0018904 20 20 0,000 0,20415958 0,23874753 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,20415958 0,23859614 ! neural tube development GO:0021915 21 20 0,000 0,20415958 0,23844494 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,20415958 0,23829393 ! protein targeting to membrane GO:0006612 22 20 0,000 0,20415958 0,23814311 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,20415958 0,23799248 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,20415958 0,23784204 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,20415958 0,23769179 ! RNA modification GO:0009451 20 20 0,000 0,20415958 0,23754173 ! single fertilization GO:0007338 21 20 0,000 0,20415958 0,23739187 ! regulation of B cell activation GO:0050864 20 20 0,000 0,20415958 0,23724219 ! coenzyme metabolic process GO:0006732 75 74 1,000 0,20459012 0,23759269 ! ribonucleotide biosynthetic process GO:0009260 75 75 1,000 0,20874513 0,24226528 ! purine ribonucleotide metabolic process GO:0009150 75 75 1,000 0,20874513 0,24211282 ! positive regulation of multicellular organismal process GO:0051240 76 76 1,000 0,21290925 0,24678726 ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,2132085 0,24697879 ! mRNA catabolic process GO:0006402 21 21 0,000 0,2132085 0,24682365 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,2132085 0,24666871 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,2132085 0,24651396 ! Notch signaling pathway GO:0007219 22 21 0,000 0,2132085 0,24635941 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,2132085 0,24620505 ! ear morphogenesis GO:0042471 21 21 0,000 0,2132085 0,24605088 ! organic anion transport GO:0015711 21 21 0,000 0,2132085 0,24589691 ! cholesterol transport GO:0030301 21 21 0,000 0,2132085 0,24574313 GO:0015918|sterol transport, ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,2132085 0,24558954 GO:0032313|regulation of Rab GTPase activity, ! regulation of protein import into nucleus GO:0042306 21 21 0,000 0,2132085 0,24543614 ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,2132085 0,24528293 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,2132085 0,24512992 ! regulation of proteolysis GO:0030162 21 21 0,000 0,2132085 0,24497709 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,2132085 0,24482446 ! regulation of protein modification process GO:0031399 79 78 1,000 0,22126194 0,25391392 ! positive regulation of protein kinase cascade GO:0010740 79 78 1,000 0,22126194 0,25375592 ! RNA export from nucleus GO:0006405 22 22 0,000 0,22215583 0,25462263 ! sister chromatid segregation GO:0000819 22 22 0,000 0,22215583 0,25446438 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,22215583 0,25430633 ! regulation of ion transport GO:0043269 22 22 0,000 0,22215583 0,25414847 ! odontogenesis GO:0042476 22 22 0,000 0,22215583 0,25399081 ! hormone-mediated signaling GO:0009755 22 22 0,000 0,22215583 0,25383335 ! embryonic skeletal system development GO:0048706 22 22 0,000 0,22215583 0,25367608 ! maintenance of protein location in cell GO:0032507 23 22 0,000 0,22215583 0,253519 ! spindle organization GO:0007051 22 22 0,000 0,22215583 0,25336212 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,22215583 0,25320543 ! cell chemotaxis GO:0060326 23 22 0,000 0,22215583 0,25304894 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,22215583 0,25289264 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,22215583 0,25273654 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,22215583 0,25258062 ! biopolymer methylation GO:0043414 22 22 0,000 0,22215583 0,2524249 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,22215583 0,25226937 ! detection of external stimulus GO:0009581 23 22 0,000 0,22215583 0,25211403 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,22215583 0,25195888 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,22215583 0,25180393 ! aerobic respiration GO:0009060 22 22 0,000 0,22215583 0,25164916 ! cytokine production GO:0001816 22 22 0,000 0,22215583 0,25149459 ! cytokinesis GO:0000910 23 22 0,000 0,22215583 0,2513402 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,22215583 0,251186 ! nuclear transport GO:0051169 79 79 1,000 0,2254491 0,25475334 GO:0006913|nucleocytoplasmic transport, ! glycoprotein biosynthetic process GO:0009101 80 80 1,000 0,22964255 0,25933285 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,2310027 0,26070911 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,2310027 0,26054955 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,2310027 0,2603902 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,2310027 0,26023103 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,2310027 0,26007207 ! endocrine system development GO:0035270 23 23 0,000 0,2310027 0,25991329 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,2310027 0,25975471 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,2310027 0,25959632 ! lipid catabolic process GO:0016042 82 81 1,000 0,23384162 0,26262651 ! gliogenesis GO:0042063 24 24 0,000 0,23975022 0,26909845 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,23975022 0,26893467 ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,23975022 0,26877108 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,23975022 0,2686077 ! fertilization GO:0009566 25 24 0,000 0,23975022 0,26844451 ! maintenance of protein location GO:0045185 25 24 0,000 0,23975022 0,26828152 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,23975022 0,26811873 ! androgen receptor signaling pathway GO:0030521 24 24 0,000 0,23975022 0,26795613 ! ribonucleotide metabolic process GO:0009259 83 83 1,000 0,24225401 0,27059039 ! cellular amino acid derivative metabolic process GO:0006575 87 84 1,000 0,24646606 0,27512837 ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,24839951 0,27711882 ! negative regulation of secretion GO:0051048 26 25 0,000 0,24839951 0,27695117 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,24839951 0,27678373 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,24839951 0,27661649 ! endosome transport GO:0016197 25 25 0,000 0,24839951 0,27644945 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,24839951 0,27628261 ! excretion GO:0007588 25 25 0,000 0,24839951 0,27611598 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,24839951 0,27594954 ! gastrulation GO:0007369 25 25 0,000 0,24839951 0,27578331 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,24839951 0,27561727 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,24839951 0,27545144 ! positive regulation of response to stimulus GO:0048584 86 85 1,000 0,25068118 0,27781444 ! hexose metabolic process GO:0019318 87 86 1,000 0,25489878 0,28231878 ! glycolysis GO:0006096 26 26 0,000 0,25695163 0,28442154 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,25695163 0,28425082 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,25695163 0,2840803 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,25695163 0,28390999 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,25695163 0,28373988 ! regulation of protein secretion GO:0050708 26 26 0,000 0,25695163 0,28356998 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,25695163 0,28340028 GO:0035150|regulation of tube size, ! purine nucleotide biosynthetic process GO:0006164 88 88 1,000 0,26333905 0,29027146 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,26540769 0,29237679 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,26540769 0,29220213 ! inner ear development GO:0048839 27 27 0,000 0,26540769 0,29202768 ! defense response to bacterium GO:0042742 27 27 0,000 0,26540769 0,29185344 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,26540769 0,29167941 ! cell growth GO:0016049 27 27 0,000 0,26540769 0,29150558 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,27376872 0,30050968 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,27376872 0,30033081 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,27376872 0,30015215 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,27376872 0,2999737 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,27376872 0,29979546 ! cartilage development GO:0051216 29 28 0,000 0,27376872 0,29961743 ! DNA replication GO:0006260 91 91 1,000 0,27600369 0,30188415 ! leukocyte migration GO:0050900 30 29 0,000 0,28203581 0,30829893 ! antigen processing and presentation GO:0019882 29 29 0,000 0,28203581 0,30811618 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,28203581 0,30793364 ! tRNA processing GO:0008033 29 29 0,000 0,28203581 0,30775133 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,28203581 0,30756922 ! adult behavior GO:0030534 30 29 0,000 0,28203581 0,30738734 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,28203581 0,30720567 ! cofactor metabolic process GO:0051186 95 94 1,000 0,28866049 0,31423584 ! transition metal ion transport GO:0000041 31 30 0,000 0,29020997 0,31573611 ! RNA catabolic process GO:0006401 30 30 0,000 0,29020997 0,31554984 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,29020997 0,31536378 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,29020997 0,31517795 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,29020997 0,31499233 ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,29020997 0,31480693 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,29020997 0,31462175 ! skeletal system morphogenesis GO:0048705 31 30 0,000 0,29020997 0,31443679 ! vascular process in circulatory system GO:0003018 31 30 0,000 0,29020997 0,31425204 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,29020997 0,31406751 GO:0019724|B cell mediated immunity, ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,29020997 0,3138832 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,29020997 0,31369911 ! establishment of organelle localization GO:0051656 31 30 0,000 0,29020997 0,31351523 ! regulation of translational initiation GO:0006446 31 31 0,000 0,29829225 0,32205777 ! membrane fusion GO:0006944 31 31 0,000 0,29829225 0,32186922 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,29829225 0,32168088 ! ion transmembrane transport GO:0034220 31 31 0,000 0,29829225 0,32149276 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! digestion GO:0007586 31 31 0,000 0,29829225 0,32130486 ! regulation of heart contraction GO:0008016 31 31 0,000 0,29829225 0,32111718 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,29829225 0,32092973 ! camera-type eye development GO:0043010 31 31 0,000 0,29829225 0,32074249 ! regulation of myeloid cell differentiation GO:0045637 32 31 0,000 0,29829225 0,32055546 ! glycoprotein metabolic process GO:0009100 99 98 1,000 0,30550062 0,32811051 ! blood circulation GO:0008015 99 98 1,000 0,30550062 0,32791941 GO:0003013|circulatory system process, ! cell redox homeostasis GO:0045454 32 32 0,000 0,30628367 0,32856857 ! glucose catabolic process GO:0006007 32 32 0,000 0,30628367 0,32837743 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,30628367 0,32818651 ! nuclear export GO:0051168 32 32 0,000 0,30628367 0,32799582 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,30628367 0,32780534 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,31418523 0,33606696 ! activation of protein kinase activity GO:0032147 35 33 0,000 0,31418523 0,33587203 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,31418523 0,33567732 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,31418523 0,33548283 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,31418523 0,33528858 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,31418523 0,33509454 ! regulation of actin filament length GO:0030832 34 34 0,000 0,32199793 0,34322856 ! muscle cell differentiation GO:0042692 35 34 0,000 0,32199793 0,34303016 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,32199793 0,34283199 ! regulation of lipid metabolic process GO:0019216 34 34 0,000 0,32199793 0,34263405 ! detection of stimulus GO:0051606 36 34 0,000 0,32199793 0,34243634 ! regulation of cellular component size GO:0032535 35 35 0,000 0,32972275 0,35044927 ! regulation of immune effector process GO:0002697 35 35 0,000 0,32972275 0,35024728 ! hydrogen transport GO:0006818 36 36 0,000 0,33736068 0,35815423 GO:0015992|proton transport, ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,33736068 0,35794803 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,33736068 0,35774208 ! positive regulation of organelle organization GO:0010638 36 36 0,000 0,33736068 0,35753636 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,33736068 0,35733088 ! activation of immune response GO:0002253 36 36 0,000 0,33736068 0,35712564 ! coagulation GO:0050817 39 36 0,000 0,33736068 0,35692063 GO:0007596|blood coagulation, ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,34491268 0,36470113 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,34491268 0,36449201 ! eye development GO:0001654 37 37 0,000 0,34491268 0,36428313 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,34491268 0,36407449 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,34491268 0,36386609 ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,34491268 0,36365793 ! adaptive immune response GO:0002250 37 37 0,000 0,34491268 0,36345001 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of secretion GO:0051047 39 38 0,000 0,3523797 0,37110616 ! neurotransmitter transport GO:0006836 40 38 0,000 0,3523797 0,37089422 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,3523797 0,37068252 ! exocytosis GO:0006887 40 38 0,000 0,3523797 0,37047107 ! hexose catabolic process GO:0019320 38 38 0,000 0,3523797 0,37025985 ! RNA elongation GO:0006354 38 38 0,000 0,3523797 0,37004888 ! regulation of neurological system process GO:0031644 38 38 0,000 0,3523797 0,36983814 ! steroid hormone receptor signaling pathway GO:0030518 38 38 0,000 0,3523797 0,36962765 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,35976268 0,37715735 ! hemostasis GO:0007599 42 39 0,000 0,35976268 0,37694293 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,35976268 0,37672876 ! response to unfolded protein GO:0006986 39 39 0,000 0,35976268 0,37651483 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,35976268 0,37630115 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,35976268 0,3760877 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,35976268 0,3758745 ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,36706257 0,38328403 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 0,000 0,36706257 0,38306699 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,37428027 0,39037835 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! amine catabolic process GO:0009310 42 41 0,000 0,37428027 0,39015755 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,37428027 0,389937 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,37428027 0,38971669 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,37428027 0,38949664 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,38141672 0,39669922 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,38141672 0,39647547 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,38141672 0,39625198 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! one-carbon metabolic process GO:0006730 42 42 0,000 0,38141672 0,39602874 ! alcohol catabolic process GO:0046164 43 43 0,000 0,3884728 0,40312802 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,3884728 0,40290117 ! mRNA transport GO:0051028 44 44 0,000 0,39544942 0,40990623 ! negative regulation of organelle organization GO:0010639 45 44 0,000 0,39544942 0,40967581 ! vitamin metabolic process GO:0006766 44 44 0,000 0,39544942 0,40944566 ! homophilic cell adhesion GO:0007156 45 45 0,000 0,40234745 0,41635393 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,40234745 0,41612028 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,40234745 0,4158869 ! protein processing GO:0016485 45 45 0,000 0,40234745 0,41565378 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,40916777 0,42246286 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,40916777 0,42222632 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,41591125 0,42894484 ! calcium ion transport GO:0006816 48 48 0,000 0,42257873 0,43557752 ! DNA recombination GO:0006310 48 48 0,000 0,42257873 0,43533404 ! divalent metal ion transport GO:0070838 49 49 0,000 0,42917107 0,44187837 ! response to bacterium GO:0009617 50 49 0,000 0,42917107 0,44163165 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,42917107 0,4413852 ! chromatin assembly GO:0031497 50 50 0,000 0,4356891 0,44783882 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,4356891 0,44758919 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! transcription initiation GO:0006352 50 50 0,000 0,4356891 0,44733984 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,44213364 0,45370396 ! positive regulation of immune response GO:0050778 51 51 0,000 0,44213364 0,45345148 ! rRNA metabolic process GO:0016072 51 51 0,000 0,44213364 0,45319928 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,44213364 0,45294736 ! ATP biosynthetic process GO:0006754 51 51 0,000 0,44213364 0,45269573 ! protein maturation GO:0051604 51 51 0,000 0,44213364 0,45244437 ! RNA localization GO:0006403 52 52 0,000 0,44850553 0,45871015 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,44850553 0,45845573 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,44850553 0,4582016 ! regulation of body fluid levels GO:0050878 55 52 0,000 0,44850553 0,45794775 ! sodium ion transport GO:0006814 53 53 0,000 0,45480555 0,46412327 ! tRNA metabolic process GO:0006399 53 53 0,000 0,45480555 0,46386642 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,45480555 0,46360986 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,45480555 0,46335358 ! hormone metabolic process GO:0042445 55 54 0,000 0,46103452 0,46944012 ! nucleosome organization GO:0034728 55 55 0,000 0,46719322 0,47544843 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,46719322 0,47518604 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! microtubule cytoskeleton organization GO:0000226 55 55 0,000 0,46719322 0,47492394 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,47328244 0,4808487 ! ATP metabolic process GO:0046034 57 57 0,000 0,47930295 0,48669716 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,47930295 0,48642915 ! sterol metabolic process GO:0016125 59 59 0,000 0,4911409 0,49816879 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,4911409 0,49789477 ! potassium ion transport GO:0006813 60 60 0,000 0,49695985 0,50351676 ! protein polymerization GO:0051258 65 60 0,000 0,49695985 0,50324011 ! cellular respiration GO:0045333 62 61 0,000 0,50271309 0,50878651 ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,50271309 0,50850726 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,50840137 0,513979 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,50840137 0,51369722 ! regulation of secretion GO:0051046 65 63 0,000 0,51402541 0,51909525 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,51402541 0,51881097 ! regulation of cytoskeleton organization GO:0051493 66 64 0,000 0,51958592 0,52413621 ! regulation of hormone levels GO:0010817 66 65 0,000 0,52508362 0,52939229 ! muscle contraction GO:0006936 67 67 0,000 0,53589335 0,53999533 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,54120677 0,54505141 ! sensory perception of sound GO:0007605 71 69 0,000 0,54646013 0,55004152 GO:0050954|sensory perception of mechanical stimulus, ! translational elongation GO:0006414 71 71 0,000 0,55678934 0,5601325 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,55678934 0,55982692 ! ribosome biogenesis GO:0042254 71 71 0,000 0,55678934 0,55952167 ! secretion by cell GO:0032940 75 72 0,000 0,5618665 0,56431606 ! muscle system process GO:0003012 72 72 0,000 0,5618665 0,5640087 ! electron transport chain GO:0022900 75 74 0,000 0,57184921 0,57371698 ! microtubule-based movement GO:0007018 82 78 0,000 0,5911458 0,59275392 ! regulation of immune response GO:0050776 78 78 0,000 0,5911458 0,5924316 ! ncRNA processing GO:0034470 83 83 0,000 0,61406298 0,61506417 ! regulation of Ras protein signal transduction GO:0046578 90 90 0,000 0,64403078 0,64473043 ! visual perception GO:0007601 93 92 0,000 0,65216278 0,65251683 GO:0050953|sensory perception of light stimulus, ! regulation of system process GO:0044057 98 98 0,000 0,67547436 0,67547436