Study Desmedt-ER-neg

Study informations

165 subnetworks in total page | file

2310 genes associated page | file

Enriched GO terms page

General informations

General Index page

Study Index page

Subnetwork 6331

score

DatasetScoreP-val 1P-val 2P-val 3Fisher Score
IPC0.75753.291e-035.250e-047.609e-011.315e-06
Loi0.22928.198e-021.182e-024.324e-014.188e-04
Schmidt0.67180.000e+000.000e+004.668e-020.000e+00
VanDeVijver0.79070.000e+000.000e+003.483e-030.000e+00
Wang0.26022.871e-034.555e-024.043e-015.288e-05

Expression data for subnetwork 6331 in each dataset

IPC | Loi | Schmidt | VanDeVijver | Wang |

Subnetwork structure for each dataset

Score for each gene in subnetwork 6331 in each dataset

Gene SymbolLinksFrequencyFrequency RankSubnetwork score rankGlobal rank IPCLoiSchmidtVanDeVijverWang
EP300EP300 on ITI EP300 on NCBI113414-0.1490.0870.1020.0520.025
CCNE2CCNE2 on ITI CCNE2 on NCBI111484124070.136-0.1780.241undef-0.055
PTPN21PTPN21 on ITI PTPN21 on NCBI5360171716770.0270.1770.2140.2050.119
TP53TP53 on ITI TP53 on NCBI85716-0.1670.148-0.0270.2520.147
ERBB2ERBB2 on ITI ERBB2 on NCBI141111-0.1030.092-0.0900.2670.046
MYH9MYH9 on ITI MYH9 on NCBI444011311108-0.1030.2270.007-0.1500.165
CSNK2BCSNK2B on ITI CSNK2B on NCBI35573183410.001-0.039-0.0040.1150.033
CDKN1ACDKN1A on ITI CDKN1A on NCBI1105150.0640.2540.030undef0.082
PRKCAPRKCA on ITI PRKCA on NCBI6315110-0.016-0.0880.1740.0950.005
PPP2R1BPPP2R1B on ITI PPP2R1B on NCBI63011411520.0420.002-0.002undef0.112
CDKN2CCDKN2C on ITI CDKN2C on NCBI161042362270.216-0.1060.202-0.024-0.081
DSTDST on ITI DST on NCBI2269125-0.0940.3430.065-0.0620.194
PLAUPLAU on ITI PLAU on NCBI121401791920.1870.1530.1410.0720.192
GNAZGNAZ on ITI GNAZ on NCBI151114784570.134-0.1160.3080.2670.011
DLG1DLG1 on ITI DLG1 on NCBI6301457452-0.0160.1730.2440.0170.123
KRT5KRT5 on ITI KRT5 on NCBI10167806780-0.1250.0460.064-0.006-0.190
AKT1AKT1 on ITI AKT1 on NCBI161042362270.0450.126-0.099undef-0.168
SERTAD4SERTAD4 on ITI SERTAD4 on NCBI8222126812250.1730.169undef-0.050undef
KATNAL1KATNAL1 on ITI KATNAL1 on NCBI11195219722030.134-0.174undefundefundef
R3HDM1R3HDM1 on ITI R3HDM1 on NCBI4440318337-0.108-0.192-0.0490.0820.223
CDK1CDK1 on ITI CDK1 on NCBI631583790.265-0.1950.1060.0880.031
RCN2RCN2 on ITI RCN2 on NCBI35574124300.0590.0510.1760.008-0.098
FGFR1FGFR1 on ITI FGFR1 on NCBI2652638615-0.0360.2000.087undef-0.015
YWHAGYWHAG on ITI YWHAG on NCBI24622962790.0670.024undef0.266undef
MYH11MYH11 on ITI MYH11 on NCBI2743216321450.084-0.0030.211undef0.094
SUPT16HSUPT16H on ITI SUPT16H on NCBI11195219722030.268-0.0280.1550.113-0.024
ENPP1ENPP1 on ITI ENPP1 on NCBI5360105510340.0880.129-0.026undef0.039
CLCA2CLCA2 on ITI CLCA2 on NCBI9196412411-0.1760.243-0.1530.191-0.000
TRAF3IP1TRAF3IP1 on ITI TRAF3IP1 on NCBI91968399-0.113-0.063-0.0880.276undef
PAMPAM on ITI PAM on NCBI10167638621-0.0350.3070.2000.0020.104
GSK3BGSK3B on ITI GSK3B on NCBI798179169-0.1300.292-0.1290.2910.057
KLF5KLF5 on ITI KLF5 on NCBI769170.0770.117-0.007-0.110-0.006
RABGEF1RABGEF1 on ITI RABGEF1 on NCBI274321972176-0.0060.1980.1370.0890.218
SERPINE1SERPINE1 on ITI SERPINE1 on NCBI82221792000.1600.2000.0560.0700.030
RUNX1RUNX1 on ITI RUNX1 on NCBI5360906890-0.1610.1400.0160.1020.025
SGOL1SGOL1 on ITI SGOL1 on NCBI2743143714330.279-0.046undefundefundef
NOLC1NOLC1 on ITI NOLC1 on NCBI4440104710320.033-0.0550.1720.012-0.064
EYA2EYA2 on ITI EYA2 on NCBI13124318316-0.0340.113-0.142undef-0.019
KHKKHK on ITI KHK on NCBI11195219722030.073-0.099-0.004undef0.152
TGFB1I1TGFB1I1 on ITI TGFB1I1 on NCBI4922116-0.1050.2290.1430.1950.298
TRIM29TRIM29 on ITI TRIM29 on NCBI82222962870.1610.240-0.150-0.0770.024
SDPRSDPR on ITI SDPR on NCBI1119521972203-0.150-0.0230.1380.0850.114
RASSF9RASSF9 on ITI RASSF9 on NCBI4440110210800.156-0.0580.1730.122-0.133
SRRM1SRRM1 on ITI SRRM1 on NCBI10167296283-0.1200.1390.2440.294-0.109
PTPN3PTPN3 on ITI PTPN3 on NCBI111486586350.0290.060-0.0670.225-0.034
RSRC1RSRC1 on ITI RSRC1 on NCBI21733663540.0230.1040.105-0.0980.212
HOXB2HOXB2 on ITI HOXB2 on NCBI33373182890.024-0.1430.0760.247-0.184
HOXA10HOXA10 on ITI HOXA10 on NCBI44401590.0460.203-0.057-0.1600.016
TOP2ATOP2A on ITI TOP2A on NCBI20811280.193-0.1680.054-0.0640.071
HBA1HBA1 on ITI HBA1 on NCBI35571411700.058-0.0420.1400.1420.131
APLP1APLP1 on ITI APLP1 on NCBI82227277030.2840.043-0.105-0.121-0.190
SLC9A3R1SLC9A3R1 on ITI SLC9A3R1 on NCBI3557173517180.0040.0170.0170.096-0.110
PTENPTEN on ITI PTEN on NCBI27501411350.0450.0550.0170.183-0.041
WT1WT1 on ITI WT1 on NCBI33371210.254-0.0390.036undef0.172
JAK2JAK2 on ITI JAK2 on NCBI27434784900.018-0.177-0.202-0.145-0.156
RDXRDX on ITI RDX on NCBI1119521972203-0.0490.0340.149-0.068-0.073
SP1SP1 on ITI SP1 on NCBI721083770.222-0.2540.2390.0200.082
MYBMYB on ITI MYB on NCBI2847366344-0.0280.0750.0020.065-0.012
FGFR4FGFR4 on ITI FGFR4 on NCBI2173179183-0.0110.188-0.089-0.018-0.049
PNPPNP on ITI PNP on NCBI27434124390.036-0.0120.108-0.0400.132
TAF1DTAF1D on ITI TAF1D on NCBI101675905660.1410.1130.041undef0.059
PIK3R1PIK3R1 on ITI PIK3R1 on NCBI127212-0.2370.3810.065undef-0.002
RPL7RPL7 on ITI RPL7 on NCBI3557143714180.189-0.1210.1660.071-0.003
FANCAFANCA on ITI FANCA on NCBI91961440.120-0.1880.106-0.127-0.053
CDK5R1CDK5R1 on ITI CDK5R1 on NCBI1795552521-0.1500.038-0.0960.1210.091
EGFREGFR on ITI EGFR on NCBI117313-0.1950.240-0.205-0.1870.065
MAP1BMAP1B on ITI MAP1B on NCBI691219-0.1230.263-0.1070.3040.100
MAPK3MAPK3 on ITI MAPK3 on NCBI63011411520.137-0.102-0.126undef-0.086
COX17COX17 on ITI COX17 on NCBI2743212921030.249-0.006-0.0940.0240.125
TNFRSF1BTNFRSF1B on ITI TNFRSF1B on NCBI2743193819220.024-0.187-0.096-0.228-0.106
IRS1IRS1 on ITI IRS1 on NCBI9196842805-0.2190.0650.1650.1020.064
INSRINSR on ITI INSR on NCBI9662362210.0630.1730.135-0.014-0.072
OPRK1OPRK1 on ITI OPRK1 on NCBI11195219722030.0110.0350.034-0.052-0.098
IKBKEIKBKE on ITI IKBKE on NCBI101675525390.227-0.041-0.095-0.1970.079
IGFBP5IGFBP5 on ITI IGFBP5 on NCBI48238380-0.0760.1100.0740.2780.181
SLC25A19SLC25A19 on ITI SLC25A19 on NCBI11195219722030.183-0.194undefundefundef
PGM2L1PGM2L1 on ITI PGM2L1 on NCBI3557412430-0.0190.220undefundefundef
HMGB2HMGB2 on ITI HMGB2 on NCBI2743216321450.214-0.0850.151undef-0.015
ITGB4ITGB4 on ITI ITGB4 on NCBI35341200.0210.313-0.1340.080-0.114
KRT18KRT18 on ITI KRT18 on NCBI82225905690.1480.100-0.0830.024-0.053
CDH2CDH2 on ITI CDH2 on NCBI101677277020.1690.109-0.0160.1230.155
SLC22A4SLC22A4 on ITI SLC22A4 on NCBI2743219721760.1240.0450.0230.0720.020
CDKN2ACDKN2A on ITI CDKN2A on NCBI60171110.263-0.1130.111undef-0.105

GO Enrichment output for subnetwork 6331 in each dataset

IPC file

NameAccession NumberLinkP-valCorrected P-val
regulation of cyclin-dependent protein kinase activityGO:0000079GO:0000079 on GO8.869E-142.167E-10
negative regulation of phosphorylationGO:0042326GO:0042326 on GO1.325E-101.619E-07
negative regulation of phosphorus metabolic processGO:0010563GO:0010563 on GO2.491E-102.029E-07
negative regulation of cell-matrix adhesionGO:0001953GO:0001953 on GO4.757E-092.905E-06
phospholipid dephosphorylationGO:0046839GO:0046839 on GO8.35E-094.08E-06
negative regulation of protein kinase B signaling cascadeGO:0051898GO:0051898 on GO2.492E-081.015E-05
negative regulation of insulin receptor signaling pathwayGO:0046627GO:0046627 on GO5.786E-082.019E-05
negative regulation of focal adhesion formationGO:0051895GO:0051895 on GO5.786E-081.767E-05
endothelial cell migrationGO:0043542GO:0043542 on GO6.173E-081.676E-05
cardiac muscle tissue developmentGO:0048738GO:0048738 on GO6.173E-081.508E-05
phosphoinositide 3-kinase cascadeGO:0014065GO:0014065 on GO1.151E-072.557E-05


Loi file

NameAccession NumberLinkP-valCorrected P-val
regulation of cyclin-dependent protein kinase activityGO:0000079GO:0000079 on GO2.137E-135.142E-10
negative regulation of phosphorylationGO:0042326GO:0042326 on GO2.346E-102.822E-07
negative regulation of phosphorus metabolic processGO:0010563GO:0010563 on GO4.405E-103.533E-07
negative regulation of cell-matrix adhesionGO:0001953GO:0001953 on GO7.186E-094.323E-06
phospholipid dephosphorylationGO:0046839GO:0046839 on GO1.164E-085.603E-06
negative regulation of protein kinase B signaling cascadeGO:0051898GO:0051898 on GO3.474E-081.393E-05
negative regulation of insulin receptor signaling pathwayGO:0046627GO:0046627 on GO8.062E-082.771E-05
negative regulation of focal adhesion formationGO:0051895GO:0051895 on GO8.062E-082.425E-05
endothelial cell migrationGO:0043542GO:0043542 on GO9.301E-082.487E-05
cardiac muscle tissue developmentGO:0048738GO:0048738 on GO9.301E-082.238E-05
phosphoinositide 3-kinase cascadeGO:0014065GO:0014065 on GO1.604E-073.507E-05


Schmidt file

NameAccession NumberLinkP-valCorrected P-val
regulation of cyclin-dependent protein kinase activityGO:0000079GO:0000079 on GO3.254E-117.484E-08
negative regulation of phosphorylationGO:0042326GO:0042326 on GO1.115E-091.282E-06
negative regulation of phosphorus metabolic processGO:0010563GO:0010563 on GO2.152E-091.65E-06
negative regulation of insulin receptor signaling pathwayGO:0046627GO:0046627 on GO2.434E-071.399E-04
insulin-like growth factor receptor signaling pathwayGO:0048009GO:0048009 on GO4.832E-072.223E-04
phosphoinositide 3-kinase cascadeGO:0014065GO:0014065 on GO4.832E-071.852E-04
cellular response to insulin stimulusGO:0032869GO:0032869 on GO6.261E-072.057E-04
regulation of insulin receptor signaling pathwayGO:0046626GO:0046626 on GO8.635E-072.483E-04
negative regulation of cell-matrix adhesionGO:0001953GO:0001953 on GO1.429E-063.651E-04
negative regulation of cell sizeGO:0045792GO:0045792 on GO2.055E-064.725E-04
negative regulation of glucose importGO:0046325GO:0046325 on GO2.229E-064.661E-04


VanDeVijver file

NameAccession NumberLinkP-valCorrected P-val
ER overload responseGO:0006983GO:0006983 on GO1.238E-050.02281858
phosphoinositide 3-kinase cascadeGO:0014065GO:0014065 on GO1.238E-050.01140929
oxygen transportGO:0015671GO:0015671 on GO2.153E-050.01322817
regulation of cell migrationGO:0030334GO:0030334 on GO3.145E-050.01449223
negative regulation of blood coagulationGO:0030195GO:0030195 on GO3.424E-050.0126202
Wnt receptor signaling pathwayGO:0016055GO:0016055 on GO3.982E-050.01223225
gas transportGO:0015669GO:0015669 on GO5.104E-050.01343771
regulation of locomotionGO:0040012GO:0040012 on GO5.784E-050.01332459
regulation of cell motionGO:0051270GO:0051270 on GO5.784E-050.01184408
negative regulation of coagulationGO:0050819GO:0050819 on GO7.246E-050.01335433
protein amino acid autophosphorylationGO:0046777GO:0046777 on GO9.153E-050.01533478


Wang file

NameAccession NumberLinkP-valCorrected P-val
regulation of cyclin-dependent protein kinase activityGO:0000079GO:0000079 on GO3.254E-117.484E-08
negative regulation of phosphorylationGO:0042326GO:0042326 on GO1.115E-091.282E-06
negative regulation of phosphorus metabolic processGO:0010563GO:0010563 on GO2.152E-091.65E-06
negative regulation of insulin receptor signaling pathwayGO:0046627GO:0046627 on GO2.434E-071.399E-04
insulin-like growth factor receptor signaling pathwayGO:0048009GO:0048009 on GO4.832E-072.223E-04
phosphoinositide 3-kinase cascadeGO:0014065GO:0014065 on GO4.832E-071.852E-04
cellular response to insulin stimulusGO:0032869GO:0032869 on GO6.261E-072.057E-04
regulation of insulin receptor signaling pathwayGO:0046626GO:0046626 on GO8.635E-072.483E-04
negative regulation of cell-matrix adhesionGO:0001953GO:0001953 on GO1.429E-063.651E-04
negative regulation of cell sizeGO:0045792GO:0045792 on GO2.055E-064.725E-04
negative regulation of glucose importGO:0046325GO:0046325 on GO2.229E-064.661E-04


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