Study Desmedt-ER-neg
Study informations
165 subnetworks in total page | file
2310 genes associated page | file
Enriched GO terms page
General informations
General Index page
Study Index page
Subnetwork 6331
score
Dataset | Score | P-val 1 | P-val 2 | P-val 3 | Fisher Score |
IPC | 0.7575 | 3.291e-03 | 5.250e-04 | 7.609e-01 | 1.315e-06 |
Loi | 0.2292 | 8.198e-02 | 1.182e-02 | 4.324e-01 | 4.188e-04 |
Schmidt | 0.6718 | 0.000e+00 | 0.000e+00 | 4.668e-02 | 0.000e+00 |
VanDeVijver | 0.7907 | 0.000e+00 | 0.000e+00 | 3.483e-03 | 0.000e+00 |
Wang | 0.2602 | 2.871e-03 | 4.555e-02 | 4.043e-01 | 5.288e-05 |
Expression data for subnetwork 6331 in each dataset
IPC |
Loi |
Schmidt |
VanDeVijver |
Wang |
Subnetwork structure for each dataset
- IPC

Score for each gene in subnetwork 6331 in each dataset
Gene Symbol | Links | Frequency | Frequency Rank | Subnetwork score rank | Global rank |
IPC | Loi | Schmidt | VanDeVijver | Wang |
EP300 |  | 113 | 4 | 1 | 4 | -0.149 | 0.087 | 0.102 | 0.052 | 0.025 |
CCNE2 |  | 11 | 148 | 412 | 407 | 0.136 | -0.178 | 0.241 | undef | -0.055 |
PTPN21 |  | 5 | 360 | 1717 | 1677 | 0.027 | 0.177 | 0.214 | 0.205 | 0.119 |
TP53 |  | 85 | 7 | 1 | 6 | -0.167 | 0.148 | -0.027 | 0.252 | 0.147 |
ERBB2 |  | 141 | 1 | 1 | 1 | -0.103 | 0.092 | -0.090 | 0.267 | 0.046 |
MYH9 |  | 4 | 440 | 1131 | 1108 | -0.103 | 0.227 | 0.007 | -0.150 | 0.165 |
CSNK2B |  | 3 | 557 | 318 | 341 | 0.001 | -0.039 | -0.004 | 0.115 | 0.033 |
CDKN1A |  | 110 | 5 | 1 | 5 | 0.064 | 0.254 | 0.030 | undef | 0.082 |
PRKCA |  | 63 | 15 | 1 | 10 | -0.016 | -0.088 | 0.174 | 0.095 | 0.005 |
PPP2R1B |  | 6 | 301 | 141 | 152 | 0.042 | 0.002 | -0.002 | undef | 0.112 |
CDKN2C |  | 16 | 104 | 236 | 227 | 0.216 | -0.106 | 0.202 | -0.024 | -0.081 |
DST |  | 22 | 69 | 1 | 25 | -0.094 | 0.343 | 0.065 | -0.062 | 0.194 |
PLAU |  | 12 | 140 | 179 | 192 | 0.187 | 0.153 | 0.141 | 0.072 | 0.192 |
GNAZ |  | 15 | 111 | 478 | 457 | 0.134 | -0.116 | 0.308 | 0.267 | 0.011 |
DLG1 |  | 6 | 301 | 457 | 452 | -0.016 | 0.173 | 0.244 | 0.017 | 0.123 |
KRT5 |  | 10 | 167 | 806 | 780 | -0.125 | 0.046 | 0.064 | -0.006 | -0.190 |
AKT1 |  | 16 | 104 | 236 | 227 | 0.045 | 0.126 | -0.099 | undef | -0.168 |
SERTAD4 |  | 8 | 222 | 1268 | 1225 | 0.173 | 0.169 | undef | -0.050 | undef |
KATNAL1 |  | 1 | 1195 | 2197 | 2203 | 0.134 | -0.174 | undef | undef | undef |
R3HDM1 |  | 4 | 440 | 318 | 337 | -0.108 | -0.192 | -0.049 | 0.082 | 0.223 |
CDK1 |  | 63 | 15 | 83 | 79 | 0.265 | -0.195 | 0.106 | 0.088 | 0.031 |
RCN2 |  | 3 | 557 | 412 | 430 | 0.059 | 0.051 | 0.176 | 0.008 | -0.098 |
FGFR1 |  | 26 | 52 | 638 | 615 | -0.036 | 0.200 | 0.087 | undef | -0.015 |
YWHAG |  | 24 | 62 | 296 | 279 | 0.067 | 0.024 | undef | 0.266 | undef |
MYH11 |  | 2 | 743 | 2163 | 2145 | 0.084 | -0.003 | 0.211 | undef | 0.094 |
SUPT16H |  | 1 | 1195 | 2197 | 2203 | 0.268 | -0.028 | 0.155 | 0.113 | -0.024 |
ENPP1 |  | 5 | 360 | 1055 | 1034 | 0.088 | 0.129 | -0.026 | undef | 0.039 |
CLCA2 |  | 9 | 196 | 412 | 411 | -0.176 | 0.243 | -0.153 | 0.191 | -0.000 |
TRAF3IP1 |  | 9 | 196 | 83 | 99 | -0.113 | -0.063 | -0.088 | 0.276 | undef |
PAM |  | 10 | 167 | 638 | 621 | -0.035 | 0.307 | 0.200 | 0.002 | 0.104 |
GSK3B |  | 79 | 8 | 179 | 169 | -0.130 | 0.292 | -0.129 | 0.291 | 0.057 |
KLF5 |  | 76 | 9 | 1 | 7 | 0.077 | 0.117 | -0.007 | -0.110 | -0.006 |
RABGEF1 |  | 2 | 743 | 2197 | 2176 | -0.006 | 0.198 | 0.137 | 0.089 | 0.218 |
SERPINE1 |  | 8 | 222 | 179 | 200 | 0.160 | 0.200 | 0.056 | 0.070 | 0.030 |
RUNX1 |  | 5 | 360 | 906 | 890 | -0.161 | 0.140 | 0.016 | 0.102 | 0.025 |
SGOL1 |  | 2 | 743 | 1437 | 1433 | 0.279 | -0.046 | undef | undef | undef |
NOLC1 |  | 4 | 440 | 1047 | 1032 | 0.033 | -0.055 | 0.172 | 0.012 | -0.064 |
EYA2 |  | 13 | 124 | 318 | 316 | -0.034 | 0.113 | -0.142 | undef | -0.019 |
KHK |  | 1 | 1195 | 2197 | 2203 | 0.073 | -0.099 | -0.004 | undef | 0.152 |
TGFB1I1 |  | 49 | 22 | 1 | 16 | -0.105 | 0.229 | 0.143 | 0.195 | 0.298 |
TRIM29 |  | 8 | 222 | 296 | 287 | 0.161 | 0.240 | -0.150 | -0.077 | 0.024 |
SDPR |  | 1 | 1195 | 2197 | 2203 | -0.150 | -0.023 | 0.138 | 0.085 | 0.114 |
RASSF9 |  | 4 | 440 | 1102 | 1080 | 0.156 | -0.058 | 0.173 | 0.122 | -0.133 |
SRRM1 |  | 10 | 167 | 296 | 283 | -0.120 | 0.139 | 0.244 | 0.294 | -0.109 |
PTPN3 |  | 11 | 148 | 658 | 635 | 0.029 | 0.060 | -0.067 | 0.225 | -0.034 |
RSRC1 |  | 21 | 73 | 366 | 354 | 0.023 | 0.104 | 0.105 | -0.098 | 0.212 |
HOXB2 |  | 33 | 37 | 318 | 289 | 0.024 | -0.143 | 0.076 | 0.247 | -0.184 |
HOXA10 |  | 4 | 440 | 1 | 59 | 0.046 | 0.203 | -0.057 | -0.160 | 0.016 |
TOP2A |  | 20 | 81 | 1 | 28 | 0.193 | -0.168 | 0.054 | -0.064 | 0.071 |
HBA1 |  | 3 | 557 | 141 | 170 | 0.058 | -0.042 | 0.140 | 0.142 | 0.131 |
APLP1 |  | 8 | 222 | 727 | 703 | 0.284 | 0.043 | -0.105 | -0.121 | -0.190 |
SLC9A3R1 |  | 3 | 557 | 1735 | 1718 | 0.004 | 0.017 | 0.017 | 0.096 | -0.110 |
PTEN |  | 27 | 50 | 141 | 135 | 0.045 | 0.055 | 0.017 | 0.183 | -0.041 |
WT1 |  | 33 | 37 | 1 | 21 | 0.254 | -0.039 | 0.036 | undef | 0.172 |
JAK2 |  | 2 | 743 | 478 | 490 | 0.018 | -0.177 | -0.202 | -0.145 | -0.156 |
RDX |  | 1 | 1195 | 2197 | 2203 | -0.049 | 0.034 | 0.149 | -0.068 | -0.073 |
SP1 |  | 72 | 10 | 83 | 77 | 0.222 | -0.254 | 0.239 | 0.020 | 0.082 |
MYB |  | 28 | 47 | 366 | 344 | -0.028 | 0.075 | 0.002 | 0.065 | -0.012 |
FGFR4 |  | 21 | 73 | 179 | 183 | -0.011 | 0.188 | -0.089 | -0.018 | -0.049 |
PNP |  | 2 | 743 | 412 | 439 | 0.036 | -0.012 | 0.108 | -0.040 | 0.132 |
TAF1D |  | 10 | 167 | 590 | 566 | 0.141 | 0.113 | 0.041 | undef | 0.059 |
PIK3R1 |  | 127 | 2 | 1 | 2 | -0.237 | 0.381 | 0.065 | undef | -0.002 |
RPL7 |  | 3 | 557 | 1437 | 1418 | 0.189 | -0.121 | 0.166 | 0.071 | -0.003 |
FANCA |  | 9 | 196 | 1 | 44 | 0.120 | -0.188 | 0.106 | -0.127 | -0.053 |
CDK5R1 |  | 17 | 95 | 552 | 521 | -0.150 | 0.038 | -0.096 | 0.121 | 0.091 |
EGFR |  | 117 | 3 | 1 | 3 | -0.195 | 0.240 | -0.205 | -0.187 | 0.065 |
MAP1B |  | 69 | 12 | 1 | 9 | -0.123 | 0.263 | -0.107 | 0.304 | 0.100 |
MAPK3 |  | 6 | 301 | 141 | 152 | 0.137 | -0.102 | -0.126 | undef | -0.086 |
COX17 |  | 2 | 743 | 2129 | 2103 | 0.249 | -0.006 | -0.094 | 0.024 | 0.125 |
TNFRSF1B |  | 2 | 743 | 1938 | 1922 | 0.024 | -0.187 | -0.096 | -0.228 | -0.106 |
IRS1 |  | 9 | 196 | 842 | 805 | -0.219 | 0.065 | 0.165 | 0.102 | 0.064 |
INSR |  | 96 | 6 | 236 | 221 | 0.063 | 0.173 | 0.135 | -0.014 | -0.072 |
OPRK1 |  | 1 | 1195 | 2197 | 2203 | 0.011 | 0.035 | 0.034 | -0.052 | -0.098 |
IKBKE |  | 10 | 167 | 552 | 539 | 0.227 | -0.041 | -0.095 | -0.197 | 0.079 |
IGFBP5 |  | 48 | 23 | 83 | 80 | -0.076 | 0.110 | 0.074 | 0.278 | 0.181 |
SLC25A19 |  | 1 | 1195 | 2197 | 2203 | 0.183 | -0.194 | undef | undef | undef |
PGM2L1 |  | 3 | 557 | 412 | 430 | -0.019 | 0.220 | undef | undef | undef |
HMGB2 |  | 2 | 743 | 2163 | 2145 | 0.214 | -0.085 | 0.151 | undef | -0.015 |
ITGB4 |  | 35 | 34 | 1 | 20 | 0.021 | 0.313 | -0.134 | 0.080 | -0.114 |
KRT18 |  | 8 | 222 | 590 | 569 | 0.148 | 0.100 | -0.083 | 0.024 | -0.053 |
CDH2 |  | 10 | 167 | 727 | 702 | 0.169 | 0.109 | -0.016 | 0.123 | 0.155 |
SLC22A4 |  | 2 | 743 | 2197 | 2176 | 0.124 | 0.045 | 0.023 | 0.072 | 0.020 |
CDKN2A |  | 60 | 17 | 1 | 11 | 0.263 | -0.113 | 0.111 | undef | -0.105 |
GO Enrichment output for subnetwork 6331 in each dataset
Name | Accession Number | Link | P-val | Corrected P-val |
regulation of cyclin-dependent protein kinase activity | GO:0000079 |  | 8.869E-14 | 2.167E-10 |
negative regulation of phosphorylation | GO:0042326 |  | 1.325E-10 | 1.619E-07 |
negative regulation of phosphorus metabolic process | GO:0010563 |  | 2.491E-10 | 2.029E-07 |
negative regulation of cell-matrix adhesion | GO:0001953 |  | 4.757E-09 | 2.905E-06 |
phospholipid dephosphorylation | GO:0046839 |  | 8.35E-09 | 4.08E-06 |
negative regulation of protein kinase B signaling cascade | GO:0051898 |  | 2.492E-08 | 1.015E-05 |
negative regulation of insulin receptor signaling pathway | GO:0046627 |  | 5.786E-08 | 2.019E-05 |
negative regulation of focal adhesion formation | GO:0051895 |  | 5.786E-08 | 1.767E-05 |
endothelial cell migration | GO:0043542 |  | 6.173E-08 | 1.676E-05 |
cardiac muscle tissue development | GO:0048738 |  | 6.173E-08 | 1.508E-05 |
phosphoinositide 3-kinase cascade | GO:0014065 |  | 1.151E-07 | 2.557E-05 |
Name | Accession Number | Link | P-val | Corrected P-val |
regulation of cyclin-dependent protein kinase activity | GO:0000079 |  | 2.137E-13 | 5.142E-10 |
negative regulation of phosphorylation | GO:0042326 |  | 2.346E-10 | 2.822E-07 |
negative regulation of phosphorus metabolic process | GO:0010563 |  | 4.405E-10 | 3.533E-07 |
negative regulation of cell-matrix adhesion | GO:0001953 |  | 7.186E-09 | 4.323E-06 |
phospholipid dephosphorylation | GO:0046839 |  | 1.164E-08 | 5.603E-06 |
negative regulation of protein kinase B signaling cascade | GO:0051898 |  | 3.474E-08 | 1.393E-05 |
negative regulation of insulin receptor signaling pathway | GO:0046627 |  | 8.062E-08 | 2.771E-05 |
negative regulation of focal adhesion formation | GO:0051895 |  | 8.062E-08 | 2.425E-05 |
endothelial cell migration | GO:0043542 |  | 9.301E-08 | 2.487E-05 |
cardiac muscle tissue development | GO:0048738 |  | 9.301E-08 | 2.238E-05 |
phosphoinositide 3-kinase cascade | GO:0014065 |  | 1.604E-07 | 3.507E-05 |
Name | Accession Number | Link | P-val | Corrected P-val |
regulation of cyclin-dependent protein kinase activity | GO:0000079 |  | 3.254E-11 | 7.484E-08 |
negative regulation of phosphorylation | GO:0042326 |  | 1.115E-09 | 1.282E-06 |
negative regulation of phosphorus metabolic process | GO:0010563 |  | 2.152E-09 | 1.65E-06 |
negative regulation of insulin receptor signaling pathway | GO:0046627 |  | 2.434E-07 | 1.399E-04 |
insulin-like growth factor receptor signaling pathway | GO:0048009 |  | 4.832E-07 | 2.223E-04 |
phosphoinositide 3-kinase cascade | GO:0014065 |  | 4.832E-07 | 1.852E-04 |
cellular response to insulin stimulus | GO:0032869 |  | 6.261E-07 | 2.057E-04 |
regulation of insulin receptor signaling pathway | GO:0046626 |  | 8.635E-07 | 2.483E-04 |
negative regulation of cell-matrix adhesion | GO:0001953 |  | 1.429E-06 | 3.651E-04 |
negative regulation of cell size | GO:0045792 |  | 2.055E-06 | 4.725E-04 |
negative regulation of glucose import | GO:0046325 |  | 2.229E-06 | 4.661E-04 |
VanDeVijver file
Name | Accession Number | Link | P-val | Corrected P-val |
ER overload response | GO:0006983 |  | 1.238E-05 | 0.02281858 |
phosphoinositide 3-kinase cascade | GO:0014065 |  | 1.238E-05 | 0.01140929 |
oxygen transport | GO:0015671 |  | 2.153E-05 | 0.01322817 |
regulation of cell migration | GO:0030334 |  | 3.145E-05 | 0.01449223 |
negative regulation of blood coagulation | GO:0030195 |  | 3.424E-05 | 0.0126202 |
Wnt receptor signaling pathway | GO:0016055 |  | 3.982E-05 | 0.01223225 |
gas transport | GO:0015669 |  | 5.104E-05 | 0.01343771 |
regulation of locomotion | GO:0040012 |  | 5.784E-05 | 0.01332459 |
regulation of cell motion | GO:0051270 |  | 5.784E-05 | 0.01184408 |
negative regulation of coagulation | GO:0050819 |  | 7.246E-05 | 0.01335433 |
protein amino acid autophosphorylation | GO:0046777 |  | 9.153E-05 | 0.01533478 |
Name | Accession Number | Link | P-val | Corrected P-val |
regulation of cyclin-dependent protein kinase activity | GO:0000079 |  | 3.254E-11 | 7.484E-08 |
negative regulation of phosphorylation | GO:0042326 |  | 1.115E-09 | 1.282E-06 |
negative regulation of phosphorus metabolic process | GO:0010563 |  | 2.152E-09 | 1.65E-06 |
negative regulation of insulin receptor signaling pathway | GO:0046627 |  | 2.434E-07 | 1.399E-04 |
insulin-like growth factor receptor signaling pathway | GO:0048009 |  | 4.832E-07 | 2.223E-04 |
phosphoinositide 3-kinase cascade | GO:0014065 |  | 4.832E-07 | 1.852E-04 |
cellular response to insulin stimulus | GO:0032869 |  | 6.261E-07 | 2.057E-04 |
regulation of insulin receptor signaling pathway | GO:0046626 |  | 8.635E-07 | 2.483E-04 |
negative regulation of cell-matrix adhesion | GO:0001953 |  | 1.429E-06 | 3.651E-04 |
negative regulation of cell size | GO:0045792 |  | 2.055E-06 | 4.725E-04 |
negative regulation of glucose import | GO:0046325 |  | 2.229E-06 | 4.661E-04 |