pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6331-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 10,000 8,869E-14 2,167E-10 ! negative regulation of phosphorylation GO:0042326 52 24 6,000 1,325E-10 1,619E-07 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 6,000 2,491E-10 2,029E-07 GO:0045936|negative regulation of phosphate metabolic process, ! negative regulation of cell-matrix adhesion GO:0001953 37 11 4,000 4,757E-09 2,905E-06 GO:0010812|negative regulation of cell-substrate adhesion, ! phospholipid dephosphorylation GO:0046839 12 5 3,000 8,35E-09 4,08E-06 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 3,000 2,492E-08 1,015E-05 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 3,000 5,786E-08 2,019E-05 ! negative regulation of focal adhesion formation GO:0051895 21 7 3,000 5,786E-08 1,767E-05 ! endothelial cell migration GO:0043542 31 17 4,000 6,173E-08 1,676E-05 ! cardiac muscle tissue development GO:0048738 34 17 4,000 6,173E-08 1,508E-05 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 3,000 1,151E-07 2,557E-05 ! regulation of focal adhesion formation GO:0051893 23 8 3,000 1,151E-07 2,344E-05 ! cellular response to insulin stimulus GO:0032869 85 38 5,000 1,556E-07 2,925E-05 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 3,000 2,062E-07 3,598E-05 ! negative regulation of cell size GO:0045792 144 69 6,000 3,23E-07 5,261E-05 ! regulation of cell-matrix adhesion GO:0001952 81 23 4,000 3,253E-07 4,966E-05 GO:0010810|regulation of cell-substrate adhesion, ! regulation of insulin receptor signaling pathway GO:0046626 22 10 3,000 3,419E-07 4,913E-05 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 3,000 3,419E-07 4,64E-05 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 5,000 5,058E-07 6,504E-05 ! negative regulation of glucose import GO:0046325 18 11 3,000 5,346E-07 6,53E-05 GO:0010829|negative regulation of glucose transport, ! response to insulin stimulus GO:0032868 98 47 5,000 5,767E-07 6,709E-05 ! insulin receptor signaling pathway GO:0008286 66 27 4,000 7,641E-07 8,485E-05 ! ribosomal large subunit biogenesis GO:0042273 13 13 3,000 1,147E-06 1,218E-04 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 3,000 1,597E-06 1,626E-04 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 2,000 2,614E-06 2,555E-04 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! microvillus organization GO:0032528 8 5 2,000 2,614E-06 2,457E-04 GO:0030033|microvillus assembly, ! meiotic chromosome segregation GO:0045132 10 5 2,000 2,614E-06 2,366E-04 ! response to peptide hormone stimulus GO:0043434 129 64 5,000 3,676E-06 3,207E-04 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 3,000 3,74E-06 3,151E-04 ! negative regulation of cell adhesion GO:0007162 94 37 4,000 3,915E-06 3,188E-04 ! regulation of protein stability GO:0031647 77 38 4,000 4,484E-06 3,534E-04 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 3,000 4,784E-06 3,652E-04 ! negative regulation of cell growth GO:0030308 142 67 5,000 4,814E-06 3,564E-04 ! establishment of spindle localization GO:0051293 16 6 2,000 5,204E-06 3,739E-04 GO:0051653|spindle localization, ! cellular anion homeostasis GO:0030002 11 6 2,000 5,204E-06 3,632E-04 GO:0055081|anion homeostasis, ! negative regulation of protein kinase activity GO:0006469 144 69 5,000 5,722E-06 3,883E-04 ! inositol metabolic process GO:0006020 33 19 3,000 6,029E-06 3,981E-04 ! negative regulation of kinase activity GO:0033673 145 70 5,000 6,225E-06 4,002E-04 ! apoptotic mitochondrial changes GO:0008637 42 20 3,000 7,498E-06 4,697E-04 ! regulation of glucose import GO:0046324 30 20 3,000 7,498E-06 4,58E-04 GO:0010827|regulation of glucose transport, ! negative regulation of transferase activity GO:0051348 155 74 5,000 8,608E-06 5,129E-04 ! fibrinolysis GO:0042730 11 7 2,000 9,064E-06 5,272E-04 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 3,000 9,216E-06 5,236E-04 ! induction of apoptosis by intracellular signals GO:0008629 95 45 4,000 1,052E-05 5,842E-04 ! negative regulation of cell migration GO:0030336 122 46 4,000 1,174E-05 6,376E-04 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 2,000 1,443E-05 7,665E-04 ! ER overload response GO:0006983 13 8 2,000 1,443E-05 7,502E-04 ! regulation of T cell differentiation in the thymus GO:0033081 14 8 2,000 1,443E-05 7,346E-04 ! regulation of mast cell proliferation GO:0070666 89 49 4,000 1,608E-05 8,018E-04 ! negative regulation of growth GO:0045926 168 85 5,000 1,916E-05 9,361E-04 ! cellular response to hormone stimulus GO:0032870 182 85 5,000 1,916E-05 9,178E-04 ! induction of positive chemotaxis GO:0050930 17 9 2,000 2,155E-05 1,012E-03 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 2,000 2,155E-05 9,931E-04 ! regulation of leukocyte proliferation GO:0070663 97 53 4,000 2,37E-05 1,072E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of angiogenesis GO:0045765 125 54 4,000 2,598E-05 1,154E-03 ! response to UV GO:0009411 120 55 4,000 2,843E-05 1,24E-03 ! negative regulation of cell motion GO:0051271 142 55 4,000 2,843E-05 1,219E-03 ! regulation of cell adhesion GO:0030155 241 92 5,000 3,009E-05 1,267E-03 ! negative regulation of protein modification process GO:0031400 66 28 3,000 3,043E-05 1,26E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 2,000 3,063E-05 1,247E-03 ! DNA ligation GO:0006266 18 10 2,000 3,063E-05 1,227E-03 ! negative regulation of protein kinase cascade GO:0010741 72 30 3,000 4,032E-05 1,589E-03 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 2,000 4,192E-05 1,626E-03 ! chondrocyte differentiation GO:0002062 27 11 2,000 4,192E-05 1,6E-03 ! interphase of mitotic cell cycle GO:0051329 224 98 5,000 4,301E-05 1,617E-03 ! lipid modification GO:0030258 112 60 4,000 4,349E-05 1,61E-03 ! negative regulation of response to stimulus GO:0048585 106 61 4,000 4,712E-05 1,718E-03 ! positive regulation of cellular catabolic process GO:0031331 34 12 2,000 5,563E-05 1,999E-03 ! regulation of B cell proliferation GO:0030888 22 12 2,000 5,563E-05 1,97E-03 ! regulation of positive chemotaxis GO:0050926 22 12 2,000 5,563E-05 1,941E-03 GO:0050927|positive regulation of positive chemotaxis, ! negative regulation of mast cell proliferation GO:0070667 24 12 2,000 5,563E-05 1,914E-03 GO:0042130|negative regulation of T cell proliferation, ! protein amino acid autophosphorylation GO:0046777 157 64 4,000 5,945E-05 2,017E-03 ! regulation of monooxygenase activity GO:0032768 35 13 2,000 7,197E-05 2,409E-03 ! chromosome segregation GO:0007059 127 67 4,000 7,413E-05 2,447E-03 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 4,000 8,537E-05 2,781E-03 ! oxygen transport GO:0015671 22 14 2,000 9,117E-05 2,93E-03 ! cell cycle checkpoint GO:0000075 145 71 4,000 9,788E-05 3,105E-03 ! regulation of the force of heart contraction GO:0002026 31 15 2,000 1,134E-04 3,552E-03 ! G1/S transition checkpoint GO:0031575 37 15 2,000 1,134E-04 3,507E-03 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 2,000 1,389E-04 4,242E-03 ! negative regulation of leukocyte proliferation GO:0070664 32 16 2,000 1,389E-04 4,19E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 2,000 1,389E-04 4,139E-03 ! phosphoinositide metabolic process GO:0030384 146 77 4,000 1,44E-04 4,237E-03 ! regulation of T cell differentiation GO:0045580 78 42 3,000 1,55E-04 4,508E-03 ! neutrophil chemotaxis GO:0030593 29 17 2,000 1,679E-04 4,825E-03 ! negative regulation of blood coagulation GO:0030195 25 17 2,000 1,679E-04 4,769E-03 ! gas transport GO:0015669 26 17 2,000 1,679E-04 4,715E-03 ! regulation of T cell proliferation GO:0042129 80 43 3,000 1,7E-04 4,721E-03 ! positive regulation of phosphorylation GO:0042327 149 81 4,000 1,828E-04 5,018E-03 ! protein import into nucleus GO:0006606 174 82 4,000 1,937E-04 5,257E-03 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 2,000 2,005E-04 5,383E-03 ! polyol metabolic process GO:0019751 77 45 3,000 2,032E-04 5,397E-03 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 4,000 2,05E-04 5,386E-03 GO:0045937|positive regulation of phosphate metabolic process, ! nuclear import GO:0051170 177 83 4,000 2,05E-04 5,328E-03 ! leukocyte migration GO:0050900 75 46 3,000 2,215E-04 5,696E-03 ! positive regulation of cell cycle GO:0045787 96 48 3,000 2,614E-04 6,653E-03 ! regulation of inflammatory response GO:0050727 84 48 3,000 2,614E-04 6,585E-03 ! positive regulation of angiogenesis GO:0045766 50 20 2,000 2,775E-04 6,917E-03 ! regulation of carbohydrate metabolic process GO:0006109 37 20 2,000 2,775E-04 6,847E-03 GO:0010675|regulation of cellular carbohydrate metabolic process, ! peptidyl-serine phosphorylation GO:0018105 44 20 2,000 2,775E-04 6,779E-03 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 2,000 2,775E-04 6,712E-03 ! negative regulation of T cell activation GO:0050868 41 20 2,000 2,775E-04 6,646E-03 ! negative regulation of coagulation GO:0050819 30 20 2,000 2,775E-04 6,581E-03 ! regulation of lymphocyte differentiation GO:0045619 92 49 3,000 2,833E-04 6,654E-03 ! protein localization in nucleus GO:0034504 192 89 4,000 2,841E-04 6,61E-03 ! positive regulation of inflammatory response GO:0050729 41 21 2,000 3,222E-04 7,426E-03 ! inactivation of MAPK activity GO:0000188 45 22 2,000 3,713E-04 8,477E-03 ! apoptotic nuclear changes GO:0030262 34 22 2,000 3,713E-04 8,399E-03 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 2,000 3,713E-04 8,322E-03 ! positive regulation of locomotion GO:0040017 44 22 2,000 3,713E-04 8,246E-03 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! peptidyl-serine modification GO:0018209 50 22 2,000 3,713E-04 8,172E-03 ! cardiac muscle fiber development GO:0048739 12 5 1,000 4,08E-04 8,9E-03 ! response to food GO:0032094 6 5 1,000 4,08E-04 8,821E-03 ! regulation of glycogen metabolic process GO:0070873 10 5 1,000 4,08E-04 8,744E-03 GO:0032881|regulation of polysaccharide metabolic process, ! base-excision repair, DNA ligation GO:0006288 6 5 1,000 4,08E-04 8,668E-03 ! metaphase GO:0051323 11 5 1,000 4,08E-04 8,593E-03 ! protein insertion into membrane GO:0051205 17 5 1,000 4,08E-04 8,52E-03 ! stem cell division GO:0017145 11 5 1,000 4,08E-04 8,448E-03 GO:0048103|somatic stem cell division, ! carnitine metabolic process GO:0009437 8 5 1,000 4,08E-04 8,377E-03 GO:0006577|betaine metabolic process, ! regulation of mitochondrial membrane permeability GO:0046902 15 5 1,000 4,08E-04 8,307E-03 ! positive regulation of glycolysis GO:0045821 13 5 1,000 4,08E-04 8,238E-03 ! anagen GO:0042640 7 5 1,000 4,08E-04 8,171E-03 ! positive regulation of viral genome replication GO:0045070 9 5 1,000 4,08E-04 8,104E-03 ! skeletal myofibril assembly GO:0014866 12 5 1,000 4,08E-04 8,039E-03 ! muscle cell migration GO:0014812 8 5 1,000 4,08E-04 7,975E-03 ! morphogenesis of an epithelial sheet GO:0002011 11 5 1,000 4,08E-04 7,911E-03 ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 4,08E-04 7,849E-03 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 1,000 4,08E-04 7,788E-03 ! regulation of chemotaxis GO:0050920 45 23 2,000 4,25E-04 8,048E-03 ! regulation of cellular catabolic process GO:0031329 55 24 2,000 4,834E-04 9,084E-03 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 2,000 4,834E-04 9,014E-03 ! sex determination GO:0007530 48 24 2,000 4,834E-04 8,946E-03 ! regulation of oxidoreductase activity GO:0051341 48 24 2,000 4,834E-04 8,879E-03 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 2,000 4,834E-04 8,812E-03 ! positive regulation of cell migration GO:0030335 137 58 3,000 5,421E-04 9,81E-03 ! protein import into nucleus, translocation GO:0000060 51 25 2,000 5,467E-04 9,82E-03 ! chromosome condensation GO:0030261 48 25 2,000 5,467E-04 9,748E-03 ! regulation of behavior GO:0050795 48 25 2,000 5,467E-04 9,678E-03 ! protein tetramerization GO:0051262 57 25 2,000 5,467E-04 9,608E-03 ! regulation of retroviral genome replication GO:0045091 8 6 1,000 6,094E-04 0,01063481 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 1,000 6,094E-04 0,01055939 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 1,000 6,094E-04 0,01048503 ! carnitine transport GO:0015879 10 6 1,000 6,094E-04 0,01041171 GO:0015838|betaine transport, ! neural nucleus development GO:0048857 19 6 1,000 6,094E-04 0,0103394 ! nucleoside catabolic process GO:0009164 10 6 1,000 6,094E-04 0,0102681 ! hair follicle maturation GO:0048820 8 6 1,000 6,094E-04 0,01019777 ! negative regulation of neuroblast proliferation GO:0007406 25 6 1,000 6,094E-04 0,01012839 ! cytoplasmic microtubule organization GO:0031122 18 6 1,000 6,094E-04 0,01005996 ! negative regulation of B cell activation GO:0050869 14 6 1,000 6,094E-04 9,992E-03 ! molting cycle process GO:0022404 52 26 2,000 6,151E-04 0,01001718 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! response to endoplasmic reticulum stress GO:0034976 46 26 2,000 6,151E-04 9,951E-03 ! regulation of blood coagulation GO:0030193 46 26 2,000 6,151E-04 9,885E-03 ! negative regulation of lymphocyte activation GO:0051250 55 27 2,000 6,887E-04 0,01099603 ! regulation of fibroblast proliferation GO:0048145 56 28 2,000 7,676E-04 0,01217765 ! base-excision repair GO:0006284 41 28 2,000 7,676E-04 0,01209909 ! integrin-mediated signaling pathway GO:0007229 160 64 3,000 7,878E-04 0,01233645 ! positive regulation of cell motion GO:0051272 157 65 3,000 8,352E-04 0,0129963 ! regulation of helicase activity GO:0051095 16 7 1,000 8,496E-04 0,0131365 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 1,000 8,496E-04 0,01305388 ! Golgi to plasma membrane transport GO:0006893 14 7 1,000 8,496E-04 0,01297229 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 8,496E-04 0,01289172 ! neuron adhesion GO:0007158 14 7 1,000 8,496E-04 0,01281214 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 8,496E-04 0,01273354 ! DNA ligation during DNA repair GO:0051103 12 7 1,000 8,496E-04 0,01265589 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 1,000 8,496E-04 0,01257919 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! male sex determination GO:0030238 15 7 1,000 8,496E-04 0,01250341 ! monocyte differentiation GO:0030224 16 7 1,000 8,496E-04 0,01242854 ! centrosome duplication GO:0051298 14 7 1,000 8,496E-04 0,01235456 ! G1 DNA damage checkpoint GO:0031571 20 7 1,000 8,496E-04 0,01228146 ! B cell lineage commitment GO:0002326 21 7 1,000 8,496E-04 0,01220921 ! cranial nerve morphogenesis GO:0021602 12 7 1,000 8,496E-04 0,01213782 ! positive regulation of monooxygenase activity GO:0032770 12 7 1,000 8,496E-04 0,01206725 ! T cell lineage commitment GO:0002360 16 7 1,000 8,496E-04 0,01199749 ! axonal fasciculation GO:0007413 19 7 1,000 8,496E-04 0,01192854 ! ER-nuclear signaling pathway GO:0006984 52 29 2,000 8,522E-04 0,01189626 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 2,000 8,522E-04 0,01182867 ! regulation of B cell activation GO:0050864 55 30 2,000 9,424E-04 0,01300687 ! regulation of coagulation GO:0050818 52 30 2,000 9,424E-04 0,0129338 ! cellular response to extracellular stimulus GO:0031668 52 31 2,000 1,038E-03 0,01417221 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 2,000 1,038E-03 0,01409348 ! negative regulation of leukocyte activation GO:0002695 60 31 2,000 1,038E-03 0,01401561 ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 1,000 1,128E-03 0,01514104 ! regulation of lipid kinase activity GO:0043550 17 8 1,000 1,128E-03 0,0150583 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 1,128E-03 0,01497646 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 1,128E-03 0,01489551 ! DNA topological change GO:0006265 12 8 1,000 1,128E-03 0,01481542 ! nucleosome disassembly GO:0006337 14 8 1,000 1,128E-03 0,0147362 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! response to tumor cell GO:0002347 16 8 1,000 1,128E-03 0,01465781 ! regulation of respiratory burst GO:0060263 12 8 1,000 1,128E-03 0,01458026 ! spindle organization GO:0007051 50 32 2,000 1,14E-03 0,01466326 ! positive regulation of catabolic process GO:0009896 72 32 2,000 1,14E-03 0,01458649 ! leukocyte chemotaxis GO:0030595 55 33 2,000 1,249E-03 0,01588611 GO:0060326|cell chemotaxis, ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 3,000 1,357E-03 0,01717474 ! cell fate specification GO:0001708 56 34 2,000 1,363E-03 0,01716236 ! negative regulation of MAP kinase activity GO:0043407 78 34 2,000 1,363E-03 0,01707435 ! phosphoinositide-mediated signaling GO:0048015 141 75 3,000 1,426E-03 0,01777541 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 1,444E-03 0,01790845 ! regulation of glycolysis GO:0006110 20 9 1,000 1,444E-03 0,017818 ! microtubule bundle formation GO:0001578 22 9 1,000 1,444E-03 0,01772846 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 1,000 1,444E-03 0,01763982 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 1,000 1,444E-03 0,01755206 ! calcium-mediated signaling GO:0019722 67 35 2,000 1,484E-03 0,01794274 ! regulation of catabolic process GO:0009894 173 77 3,000 1,572E-03 0,01891825 ! mitotic sister chromatid segregation GO:0000070 63 36 2,000 1,611E-03 0,01929046 ! regulation of proteolysis GO:0030162 77 36 2,000 1,611E-03 0,01919636 ! sister chromatid segregation GO:0000819 65 37 2,000 1,745E-03 0,02069059 ! regulation of microtubule-based process GO:0032886 86 37 2,000 1,745E-03 0,02059064 ! negative regulation of cell activation GO:0050866 69 37 2,000 1,745E-03 0,02049165 ! regulation of developmental growth GO:0048638 16 10 1,000 1,797E-03 0,02101074 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 1,797E-03 0,02091069 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 1,797E-03 0,02081159 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 1,000 1,797E-03 0,02071342 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 1,000 1,797E-03 0,02061618 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 1,000 1,797E-03 0,02051984 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 1,000 1,797E-03 0,0204244 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 1,000 1,797E-03 0,02032984 ! glucan biosynthetic process GO:0009250 14 10 1,000 1,797E-03 0,02023615 GO:0005978|glycogen biosynthetic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 1,000 1,797E-03 0,02014333 ! motor axon guidance GO:0008045 22 10 1,000 1,797E-03 0,02005135 ! protein heterooligomerization GO:0051291 17 10 1,000 1,797E-03 0,01996021 ! regulation of fat cell differentiation GO:0045598 18 10 1,000 1,797E-03 0,01986989 ! induction of an organ GO:0001759 17 10 1,000 1,797E-03 0,01978039 ! quaternary ammonium group transport GO:0015697 22 10 1,000 1,797E-03 0,01969168 ! positive regulation of viral reproduction GO:0048524 19 10 1,000 1,797E-03 0,01960378 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 1,000 1,797E-03 0,01951665 GO:0043470|regulation of carbohydrate catabolic process, ! negative regulation of organelle organization GO:0010639 181 80 3,000 1,81E-03 0,01956389 ! meiosis I GO:0007127 74 38 2,000 1,885E-03 0,02028968 ! glycogen metabolic process GO:0005977 63 38 2,000 1,885E-03 0,02020069 ! meiosis GO:0007126 143 81 3,000 1,894E-03 0,02020928 GO:0051327|M phase of meiotic cell cycle, ! meiotic cell cycle GO:0051321 144 82 3,000 1,982E-03 0,02104778 ! mitotic cell cycle checkpoint GO:0007093 76 39 2,000 2,033E-03 0,02149795 ! positive regulation of leukocyte proliferation GO:0070665 70 39 2,000 2,033E-03 0,02140529 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! glucan metabolic process GO:0044042 64 39 2,000 2,033E-03 0,02131342 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 93 40 2,000 2,187E-03 0,02283484 ! nucleus organization GO:0006997 73 40 2,000 2,187E-03 0,02273767 ! cortical actin cytoskeleton organization GO:0030866 29 11 1,000 2,188E-03 0,02264542 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 1,000 2,188E-03 0,02254987 ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 2,188E-03 0,02245513 ! negative regulation of proteolysis GO:0045861 25 11 1,000 2,188E-03 0,02236117 ! syncytium formation GO:0006949 20 11 1,000 2,188E-03 0,022268 ! regulation of intracellular pH GO:0051453 21 11 1,000 2,188E-03 0,0221756 ! negative regulation of ossification GO:0030279 27 11 1,000 2,188E-03 0,02208397 ! apical protein localization GO:0045176 18 11 1,000 2,188E-03 0,02199309 ! regulation of embryonic development GO:0045995 35 11 1,000 2,188E-03 0,02190295 ! negative regulation of transport GO:0051051 164 85 3,000 2,26E-03 0,02253362 ! establishment or maintenance of cell polarity GO:0007163 96 41 2,000 2,349E-03 0,02332525 ! mitochondrion organization GO:0007005 159 87 3,000 2,46E-03 0,02432693 ! cytokinesis GO:0000910 84 42 2,000 2,518E-03 0,02479946 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 1,000 2,614E-03 0,0256466 ! cortical cytoskeleton organization GO:0030865 30 12 1,000 2,614E-03 0,02554402 ! virus-host interaction GO:0019048 30 12 1,000 2,614E-03 0,02544225 ! oligodendrocyte differentiation GO:0048709 17 12 1,000 2,614E-03 0,02534129 ! cranial nerve development GO:0021545 23 12 1,000 2,614E-03 0,02524112 ! histone acetylation GO:0016573 27 12 1,000 2,614E-03 0,02514175 ! mRNA polyadenylation GO:0006378 24 12 1,000 2,614E-03 0,02504315 ! autonomic nervous system development GO:0048483 24 12 1,000 2,614E-03 0,02494533 ! peptidyl-lysine modification GO:0018205 21 12 1,000 2,614E-03 0,02484826 ! T cell homeostasis GO:0043029 28 12 1,000 2,614E-03 0,02475195 ! developmental induction GO:0031128 22 12 1,000 2,614E-03 0,02465639 GO:0045168|cell-cell signaling involved in cell fate specification, ! establishment of cell polarity GO:0030010 21 12 1,000 2,614E-03 0,02456155 ! localization within membrane GO:0051668 26 12 1,000 2,614E-03 0,02446745 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 2,000 2,694E-03 0,02511595 ! regulation of myeloid cell differentiation GO:0045637 105 43 2,000 2,694E-03 0,02502045 ! positive regulation of protein modification process GO:0031401 156 90 3,000 2,781E-03 0,02573916 ! energy reserve metabolic process GO:0006112 76 44 2,000 2,877E-03 0,02652302 ! negative regulation of protein complex disassembly GO:0043242 113 44 2,000 2,877E-03 0,02642331 ! positive regulation of response to external stimulus GO:0032103 88 44 2,000 2,877E-03 0,02632435 ! regulation of epithelial cell proliferation GO:0050678 122 45 2,000 3,068E-03 0,02796708 ! response to X-ray GO:0010165 28 13 1,000 3,076E-03 0,02793727 ! asymmetric protein localization GO:0008105 24 13 1,000 3,076E-03 0,0278338 ! membrane protein proteolysis GO:0033619 33 13 1,000 3,076E-03 0,02773109 GO:0006509|membrane protein ectodomain proteolysis, ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 1,000 3,076E-03 0,02762914 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 35 13 1,000 3,076E-03 0,02752794 ! nucleoside triphosphate catabolic process GO:0009143 22 13 1,000 3,076E-03 0,02742747 ! mRNA 3'-end processing GO:0031124 25 13 1,000 3,076E-03 0,02732773 ! positive regulation of MAP kinase activity GO:0043406 174 93 3,000 3,131E-03 0,02771465 ! regulation of gene-specific transcription GO:0032583 102 46 2,000 3,267E-03 0,02880992 ! regulation of defense response GO:0031347 171 95 3,000 3,38E-03 0,02970367 ! negative regulation of multicellular organismal process GO:0051241 174 95 3,000 3,38E-03 0,02959721 ! regulation of T cell activation GO:0050863 175 96 3,000 3,51E-03 0,03062072 ! myotube differentiation GO:0014902 26 14 1,000 3,574E-03 0,0310695 ! hair follicle morphogenesis GO:0031069 27 14 1,000 3,574E-03 0,03095932 ! RNA polyadenylation GO:0043631 32 14 1,000 3,574E-03 0,03084992 ! lipid localization GO:0010876 32 14 1,000 3,574E-03 0,0307413 GO:0019915|lipid storage, ! regulation of cellular pH GO:0030641 27 14 1,000 3,574E-03 0,03063343 ! response to gamma radiation GO:0010332 30 14 1,000 3,574E-03 0,03052632 ! regulation of RNA stability GO:0043487 33 14 1,000 3,574E-03 0,03041996 ! release of cytochrome c from mitochondria GO:0001836 31 14 1,000 3,574E-03 0,03031433 ! positive regulation of defense response GO:0031349 88 48 2,000 3,687E-03 0,03116741 ! cellular component disassembly GO:0022411 89 48 2,000 3,687E-03 0,03105994 ! skeletal muscle tissue development GO:0007519 223 100 3,000 4,061E-03 0,03409205 GO:0060538|skeletal muscle organ development, ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 4,106E-03 0,03435294 ! negative regulation of bone remodeling GO:0046851 34 15 1,000 4,106E-03 0,0342357 ! copper ion transport GO:0006825 22 15 1,000 4,106E-03 0,03411925 ! actin cytoskeleton reorganization GO:0031532 38 15 1,000 4,106E-03 0,03400359 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 1,000 4,106E-03 0,03388871 ! intermediate filament cytoskeleton organization GO:0045104 34 15 1,000 4,106E-03 0,03377461 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 4,106E-03 0,03366127 ! cofactor transport GO:0051181 30 15 1,000 4,106E-03 0,03354869 ! lymphocyte homeostasis GO:0002260 33 15 1,000 4,106E-03 0,03343687 ! induction of apoptosis by extracellular signals GO:0008624 99 50 2,000 4,139E-03 0,03359294 ! activation of caspase activity GO:0006919 95 50 2,000 4,139E-03 0,0334817 ! negative regulation of immune system process GO:0002683 101 51 2,000 4,377E-03 0,03529023 ! regulation of protein complex disassembly GO:0043244 127 52 2,000 4,623E-03 0,03715226 ! DNA-dependent DNA replication GO:0006261 82 52 2,000 4,623E-03 0,03703045 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 4,673E-03 0,03730583 ! bone remodeling GO:0046849 28 16 1,000 4,673E-03 0,03718431 ! heterophilic cell adhesion GO:0007157 43 16 1,000 4,673E-03 0,03706358 ! regulation of transmembrane transporter activity GO:0022898 27 16 1,000 4,673E-03 0,03694364 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! intermediate filament-based process GO:0045103 36 16 1,000 4,673E-03 0,03682446 ! axon cargo transport GO:0008088 46 16 1,000 4,673E-03 0,03670606 ! DNA replication initiation GO:0006270 28 16 1,000 4,673E-03 0,03658841 ! neuron recognition GO:0008038 40 16 1,000 4,673E-03 0,03647151 ! negative regulation of inflammatory response GO:0050728 24 16 1,000 4,673E-03 0,03635536 ! negative regulation of tissue remodeling GO:0034104 37 16 1,000 4,673E-03 0,03623995 ! positive regulation of growth GO:0045927 96 53 2,000 4,877E-03 0,03770792 ! chromatin remodeling GO:0006338 122 53 2,000 4,877E-03 0,03758897 ! regulation of neuron apoptosis GO:0043523 117 53 2,000 4,877E-03 0,03747077 ! cartilage development GO:0051216 99 53 2,000 4,877E-03 0,0373533 ! synapse organization GO:0050808 102 53 2,000 4,877E-03 0,03723657 ! regulation of muscle contraction GO:0006937 94 54 2,000 5,14E-03 0,03911956 ! negative regulation of cell cycle process GO:0010948 35 17 1,000 5,273E-03 0,04000923 ! regulation of survival gene product expression GO:0045884 38 17 1,000 5,273E-03 0,03988536 ! negative regulation of microtubule depolymerization GO:0007026 50 17 1,000 5,273E-03 0,03976226 GO:0031114|regulation of microtubule depolymerization, ! DNA unwinding during replication GO:0006268 26 17 1,000 5,273E-03 0,03963992 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 1,000 5,273E-03 0,03951832 ! organic cation transport GO:0015695 32 17 1,000 5,273E-03 0,03939747 ! RNA 3'-end processing GO:0031123 37 17 1,000 5,273E-03 0,03927736 ! skeletal muscle fiber development GO:0048741 130 56 2,000 5,691E-03 0,04225596 ! negative regulation of cytoskeleton organization GO:0051494 139 56 2,000 5,691E-03 0,04212791 ! regulation of protein catabolic process GO:0042176 126 56 2,000 5,691E-03 0,04200063 ! regulation of DNA replication GO:0006275 105 56 2,000 5,691E-03 0,04187413 ! regulation of viral genome replication GO:0045069 30 18 1,000 5,908E-03 0,04333968 ! centrosome cycle GO:0007098 26 18 1,000 5,908E-03 0,04320992 ! positive regulation of proteolysis GO:0045862 36 18 1,000 5,908E-03 0,04308093 ! epidermis morphogenesis GO:0048730 43 18 1,000 5,908E-03 0,04295271 ! negative regulation of protein catabolic process GO:0042177 42 18 1,000 5,908E-03 0,04282526 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 1,000 5,908E-03 0,04269856 ! nerve development GO:0021675 34 18 1,000 5,908E-03 0,0425726 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 1,000 5,908E-03 0,04244739 ! positive regulation of caspase activity GO:0043280 108 57 2,000 5,979E-03 0,04283199 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 131 57 2,000 5,979E-03 0,04270675 ! cellular polysaccharide metabolic process GO:0044264 93 58 2,000 6,275E-03 0,0446943 ! aging GO:0007568 112 58 2,000 6,275E-03 0,04456437 ! negative regulation of defense response GO:0031348 27 19 1,000 6,575E-03 0,04655622 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 1,000 6,575E-03 0,04642167 ! mitotic chromosome condensation GO:0007076 37 19 1,000 6,575E-03 0,04628789 ! neuromuscular junction development GO:0007528 43 19 1,000 6,575E-03 0,04615487 ! vitamin transport GO:0051180 31 19 1,000 6,575E-03 0,04602263 ! establishment of organelle localization GO:0051656 122 59 2,000 6,58E-03 0,0459305 ! regulation of heart contraction GO:0008016 123 61 2,000 7,217E-03 0,05022967 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 1,000 7,274E-03 0,05048645 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 7,274E-03 0,05034343 ! protein amino acid acetylation GO:0006473 41 20 1,000 7,274E-03 0,05020122 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 1,000 7,274E-03 0,05005981 ! DNA duplex unwinding GO:0032508 30 20 1,000 7,274E-03 0,04991919 GO:0032392|DNA geometric change, ! body fluid secretion GO:0007589 33 20 1,000 7,274E-03 0,04977936 ! negative regulation of translation GO:0017148 32 20 1,000 7,274E-03 0,04964031 ! viral reproductive process GO:0022415 132 62 2,000 7,548E-03 0,05136575 ! mesoderm development GO:0007498 128 63 2,000 7,889E-03 0,05353237 ! lipid phosphorylation GO:0046834 43 21 1,000 8,006E-03 0,05418015 ! smooth muscle contraction GO:0006939 48 21 1,000 8,006E-03 0,05403048 ! cellular macromolecular complex disassembly GO:0034623 44 21 1,000 8,006E-03 0,05388164 ! cell structure disassembly during apoptosis GO:0006921 32 21 1,000 8,006E-03 0,05373361 ! plasma membrane fusion GO:0045026 33 21 1,000 8,006E-03 0,0535864 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 1,000 8,006E-03 0,05343998 ! actin filament-based movement GO:0030048 47 21 1,000 8,006E-03 0,05329437 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 1,000 8,006E-03 0,05314955 ! positive regulation of protein catabolic process GO:0045732 44 22 1,000 8,77E-03 0,05806025 ! microtubule-based transport GO:0010970 59 22 1,000 8,77E-03 0,05790333 ! glutamate signaling pathway GO:0007215 48 22 1,000 8,77E-03 0,05774725 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 1,000 8,77E-03 0,05759202 ! cellular response to starvation GO:0009267 37 22 1,000 8,77E-03 0,05743762 ! cell aging GO:0007569 48 22 1,000 8,77E-03 0,05728404 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 1,000 8,77E-03 0,05713128 ! positive regulation of intracellular transport GO:0032388 42 22 1,000 8,77E-03 0,05697934 ! positive regulation of B cell activation GO:0050871 42 22 1,000 8,77E-03 0,0568282 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 1,000 8,77E-03 0,05667786 ! positive regulation of DNA replication GO:0045740 44 23 1,000 9,564E-03 0,06165108 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 1,000 9,564E-03 0,06148884 ! viral genome replication GO:0019079 44 23 1,000 9,564E-03 0,06132746 ! activation of pro-apoptotic gene products GO:0008633 51 23 1,000 9,564E-03 0,06116691 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 1,000 9,564E-03 0,06100721 ! DNA modification GO:0006304 36 23 1,000 9,564E-03 0,06084833 ! regulation of bone mineralization GO:0030500 54 23 1,000 9,564E-03 0,06069029 ! extracellular matrix organization GO:0030198 146 68 2,000 9,725E-03 0,06154821 ! viral reproduction GO:0016032 142 68 2,000 9,725E-03 0,06138917 ! cell projection assembly GO:0030031 138 68 2,000 9,725E-03 0,06123095 ! lung development GO:0030324 165 69 2,000 0,01011929 0,06355122 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 1,000 0,01038992 0,06508351 ! positive regulation of cell adhesion GO:0045785 61 24 1,000 0,01038992 0,06491706 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 1,000 0,01038992 0,06475145 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 1,000 0,01038992 0,06458669 ! purine ribonucleoside metabolic process GO:0046128 38 24 1,000 0,01038992 0,06442277 GO:0042278|purine nucleoside metabolic process, ! barbed-end actin filament capping GO:0051016 58 24 1,000 0,01038992 0,06425967 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 41 24 1,000 0,01038992 0,0640974 ! negative regulation of catabolic process GO:0009895 52 24 1,000 0,01038992 0,06393594 ! germ cell development GO:0007281 133 70 2,000 0,010523 0,06459219 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 0,01124585 0,06885618 ! myeloid leukocyte differentiation GO:0002573 46 25 1,000 0,01124585 0,06868404 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 1,000 0,01124585 0,06851276 ! regulation of transmembrane transport GO:0034762 39 25 1,000 0,01124585 0,06834233 ! vasculogenesis GO:0001570 49 25 1,000 0,01124585 0,06817275 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 1,000 0,01124585 0,068004 ! negative regulation of DNA replication GO:0008156 45 25 1,000 0,01124585 0,06783609 ! regulation of alpha-beta T cell activation GO:0046634 48 25 1,000 0,01124585 0,06766901 ! interaction with host GO:0051701 66 25 1,000 0,01124585 0,06750274 ! regulation of biomineral formation GO:0070167 56 25 1,000 0,01124585 0,0673373 ! leukocyte homeostasis GO:0001776 50 25 1,000 0,01124585 0,06717266 ! respiratory tube development GO:0030323 171 72 2,000 0,01135814 0,06767787 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 1,000 0,01213175 0,07211161 ! myelination GO:0042552 50 26 1,000 0,01213175 0,07193658 ! macromolecular complex disassembly GO:0032984 54 26 1,000 0,01213175 0,0717624 ! microtubule organizing center organization GO:0031023 42 26 1,000 0,01213175 0,07158906 GO:0051297|centrosome organization, ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 1,000 0,01213175 0,07141655 ! negative regulation of cell development GO:0010721 83 26 1,000 0,01213175 0,07124488 GO:0050768|negative regulation of neurogenesis, ! positive regulation of nuclear division GO:0051785 41 26 1,000 0,01213175 0,07107403 GO:0045840|positive regulation of mitosis, ! regulation of caspase activity GO:0043281 136 74 2,000 0,01223045 0,07148085 ! respiratory system development GO:0060541 175 74 2,000 0,01223045 0,07131026 ! organelle localization GO:0051640 155 74 2,000 0,01223045 0,07114047 ! regulation of transcription factor activity GO:0051090 137 75 2,000 0,01268063 0,07358382 GO:0090046|regulation of transcription regulator activity, ! axon guidance GO:0007411 162 75 2,000 0,01268063 0,07340945 ! negative regulation of actin filament depolymerization GO:0030835 63 27 1,000 0,0130472 0,07535297 ! negative regulation of actin filament polymerization GO:0030837 61 27 1,000 0,0130472 0,07517525 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 1,000 0,0130472 0,07499837 ! mitochondrial membrane organization GO:0007006 60 27 1,000 0,0130472 0,07482232 ! response to starvation GO:0042594 47 27 1,000 0,0130472 0,07464709 ! regulation of chromosome organization GO:0033044 49 27 1,000 0,0130472 0,07447268 ! cellular response to nutrient levels GO:0031669 45 27 1,000 0,0130472 0,07429909 ! regulation of endopeptidase activity GO:0052548 141 77 2,000 0,01360918 0,07731915 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 1,000 0,01399178 0,0793084 ! protein amino acid acylation GO:0043543 59 28 1,000 0,01399178 0,07912481 ! dendrite development GO:0016358 67 28 1,000 0,01399178 0,07894208 ! positive regulation of T cell differentiation GO:0045582 48 28 1,000 0,01399178 0,07876018 ! peptidyl-tyrosine modification GO:0018212 57 28 1,000 0,01399178 0,07857913 ! negative regulation of protein polymerization GO:0032272 63 28 1,000 0,01399178 0,0783989 ! positive regulation of lymphocyte activation GO:0051251 142 78 2,000 0,0140876 0,07875518 ! blood coagulation GO:0007596 151 79 2,000 0,01457548 0,08129658 GO:0050817|coagulation, ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 2,000 0,01457548 0,0811114 ! protein oligomerization GO:0051259 149 79 2,000 0,01457548 0,08092705 ! somitogenesis GO:0001756 52 29 1,000 0,01496508 0,08290182 ! synaptogenesis GO:0007416 46 29 1,000 0,01496508 0,08271426 ! muscle cell differentiation GO:0042692 178 81 2,000 0,01557971 0,085917 ! response to hypoxia GO:0001666 178 81 2,000 0,01557971 0,08572349 ! regulation of actin filament depolymerization GO:0030834 67 30 1,000 0,01596671 0,08765543 ! negative regulation of protein complex assembly GO:0031333 68 30 1,000 0,01596671 0,08745889 ! myofibril assembly GO:0030239 50 30 1,000 0,01596671 0,08726323 GO:0055002|striated muscle cell development, ! positive regulation of multicellular organism growth GO:0040018 55 30 1,000 0,01596671 0,08706845 ! negative regulation of transcription regulator activity GO:0090048 57 30 1,000 0,01596671 0,08687453 GO:0043433|negative regulation of transcription factor activity, ! regulation of peptidase activity GO:0052547 150 82 2,000 0,01609609 0,08738391 ! response to oxygen levels GO:0070482 183 83 2,000 0,01662202 0,09003899 ! inorganic anion transport GO:0015698 156 83 2,000 0,01662202 0,08983979 ! male gonad development GO:0008584 56 31 1,000 0,01699625 0,09165966 ! ensheathment of neurons GO:0007272 64 31 1,000 0,01699625 0,09145777 GO:0008366|axon ensheathment, ! response to heat GO:0009408 54 31 1,000 0,01699625 0,09125676 ! T cell activation GO:0042110 189 84 2,000 0,01715749 0,09192049 ! regulation of ligase activity GO:0051340 147 84 2,000 0,01715749 0,09171935 ! hemostasis GO:0007599 165 85 2,000 0,01770253 0,09442635 ! regulation of neuron differentiation GO:0045664 187 85 2,000 0,01770253 0,09422063 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 1,000 0,0180533 0,09587873 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 1,000 0,0180533 0,09567075 ! positive regulation of T cell proliferation GO:0042102 60 32 1,000 0,0180533 0,09546367 ! metanephros development GO:0001656 81 32 1,000 0,0180533 0,09525748 ! muscle cell development GO:0055001 52 32 1,000 0,0180533 0,09505219 ! mesoderm formation GO:0001707 73 32 1,000 0,0180533 0,09484777 ! peripheral nervous system development GO:0007422 68 32 1,000 0,0180533 0,09464424 ! hindbrain development GO:0030902 65 32 1,000 0,0180533 0,09444157 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 1,000 0,0180533 0,09423977 ! positive regulation of cell activation GO:0050867 161 86 2,000 0,01825714 0,09510061 GO:0002696|positive regulation of leukocyte activation, ! regulation of pH GO:0006885 56 33 1,000 0,01913748 0,09947418 ! negative regulation of response to external stimulus GO:0032102 50 33 1,000 0,01913748 0,09926298 ! positive regulation of gene-specific transcription GO:0043193 70 33 1,000 0,01913748 0,09905268 ! triglyceride metabolic process GO:0006641 46 33 1,000 0,01913748 0,09884327 ! response to ionizing radiation GO:0010212 74 33 1,000 0,01913748 0,09863474 ! regulation of DNA binding GO:0051101 167 89 2,000 0,01997852 0,1027527 ! glial cell differentiation GO:0010001 67 34 1,000 0,02024839 0,1039219 ! formation of primary germ layer GO:0001704 76 34 1,000 0,02024839 0,10370404 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 1,000 0,02024839 0,10348708 ! regulation of cell cycle process GO:0010564 161 90 2,000 0,02057153 0,10491908 ! ossification GO:0001503 205 91 2,000 0,02117414 0,10776754 ! gland development GO:0048732 220 91 2,000 0,02117414 0,10754349 ! DNA damage checkpoint GO:0000077 78 35 1,000 0,02138565 0,10839243 ! negative regulation of DNA metabolic process GO:0051053 65 35 1,000 0,02138565 0,10816802 ! regulation of synaptic plasticity GO:0048167 78 35 1,000 0,02138565 0,10794453 ! mesoderm morphogenesis GO:0048332 80 35 1,000 0,02138565 0,10772196 ! placenta development GO:0001890 53 35 1,000 0,02138565 0,10750031 ! bone development GO:0060348 206 92 2,000 0,02178637 0,10928972 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 1,000 0,02254888 0,11288301 ! negative regulation of DNA binding GO:0043392 67 36 1,000 0,02254888 0,11265217 ! negative regulation of hydrolase activity GO:0051346 66 36 1,000 0,02254888 0,11242227 ! nucleosome organization GO:0034728 143 95 2,000 0,02368074 0,11782494 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 1,000 0,02373769 0,11786824 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 1,000 0,02373769 0,11762916 ! actomyosin structure organization GO:0031032 68 37 1,000 0,02373769 0,11739105 ! tissue remodeling GO:0048771 78 37 1,000 0,02373769 0,11715389 ! androgen receptor signaling pathway GO:0030521 81 37 1,000 0,02373769 0,11691769 ! positive regulation of DNA metabolic process GO:0051054 77 38 1,000 0,02495171 0,12264997 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 1,000 0,02495171 0,12240368 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 1,000 0,02495171 0,12215838 ! embryonic skeletal system morphogenesis GO:0048704 68 38 1,000 0,02495171 0,12191407 ! neutral lipid metabolic process GO:0006638 54 38 1,000 0,02495171 0,12167072 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 1,000 0,02495171 0,12142835 ! regulation of DNA metabolic process GO:0051052 188 97 2,000 0,02499171 0,12138123 ! leukocyte differentiation GO:0002521 232 98 2,000 0,02566161 0,12438752 ! negative regulation of binding GO:0051100 71 39 1,000 0,02619057 0,12670015 ! carbohydrate homeostasis GO:0033500 59 39 1,000 0,02619057 0,12644975 GO:0042593|glucose homeostasis, ! nucleotide catabolic process GO:0009166 70 39 1,000 0,02619057 0,12620034 ! regulation of action potential in neuron GO:0019228 80 40 1,000 0,02745391 0,13202736 ! glycerol ether metabolic process GO:0006662 57 40 1,000 0,02745391 0,13176798 ! gliogenesis GO:0042063 91 41 1,000 0,02874135 0,13767672 ! monovalent inorganic cation homeostasis GO:0055067 72 41 1,000 0,02874135 0,13740729 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 1,000 0,03005255 0,14339525 ! organic ether metabolic process GO:0018904 59 42 1,000 0,03005255 0,14311573 ! regulation of intracellular protein transport GO:0033157 86 42 1,000 0,03005255 0,14283729 ! T cell differentiation GO:0030217 93 42 1,000 0,03005255 0,14255994 ! ribonucleoside metabolic process GO:0009119 64 42 1,000 0,03005255 0,14228366 ! dorsal/ventral pattern formation GO:0009953 75 42 1,000 0,03005255 0,14200845 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 0,03138713 0,14802849 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 1,000 0,03138713 0,14774327 ! calcium-dependent cell-cell adhesion GO:0016339 56 43 1,000 0,03138713 0,14745915 ! glucose transport GO:0015758 66 43 1,000 0,03138713 0,14717612 ! striated muscle cell differentiation GO:0051146 91 43 1,000 0,03138713 0,14689417 ! development of primary male sexual characteristics GO:0046546 80 43 1,000 0,03138713 0,14661331 ! segmentation GO:0035282 78 43 1,000 0,03138713 0,14633351 ! neuron migration GO:0001764 85 43 1,000 0,03138713 0,14605478 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,03180294 0,14770833 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,03180294 0,14742805 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,03180294 0,14714883 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,03180294 0,14687067 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,03180294 0,14659355 ! neuron fate determination GO:0048664 7 5 0,000 0,03180294 0,14631748 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,03180294 0,14604245 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,03180294 0,14576845 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,03180294 0,14549547 ! polyol transport GO:0015791 12 5 0,000 0,03180294 0,14522352 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,03180294 0,14495258 ! response to superoxide GO:0000303 10 5 0,000 0,03180294 0,14468265 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,03180294 0,14441372 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,03180294 0,14414579 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,03180294 0,14387886 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,03180294 0,14361291 ! female meiosis GO:0007143 10 5 0,000 0,03180294 0,14334794 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,03180294 0,14308395 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,03180294 0,14282093 ! hypothalamus development GO:0021854 9 5 0,000 0,03180294 0,14255887 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,03180294 0,14229777 ! cobalt ion transport GO:0006824 11 5 0,000 0,03180294 0,14203763 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,03180294 0,14177844 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,03180294 0,14152019 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,03180294 0,14126288 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,03180294 0,1410065 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,03180294 0,14075106 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,03180294 0,14049653 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,03180294 0,14024293 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,03180294 0,13999024 ! transposition GO:0032196 9 5 0,000 0,03180294 0,13973846 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,03180294 0,13948758 ! negative chemotaxis GO:0050919 16 5 0,000 0,03180294 0,1392376 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,03180294 0,13898852 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,03180294 0,13874033 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,03180294 0,13849302 ! behavioral response to pain GO:0048266 10 5 0,000 0,03180294 0,13824659 ! clathrin coat assembly GO:0048268 15 5 0,000 0,03180294 0,13800104 ! Notch receptor processing GO:0007220 11 5 0,000 0,03180294 0,13775635 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,03180294 0,13751254 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,03180294 0,13726958 ! micturition GO:0060073 9 5 0,000 0,03180294 0,13702748 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,03180294 0,13678624 ! copulation GO:0007620 9 5 0,000 0,03180294 0,13654584 ! glial cell fate commitment GO:0021781 14 5 0,000 0,03180294 0,13630629 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,03180294 0,13606757 ! bioluminescence GO:0008218 9 5 0,000 0,03180294 0,13582969 ! spermidine metabolic process GO:0008216 7 5 0,000 0,03180294 0,13559264 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,03180294 0,13535642 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,03180294 0,13512101 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,03180294 0,13488643 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,03180294 0,13465266 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,03180294 0,13441969 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,03180294 0,13418754 ! grooming behavior GO:0007625 6 5 0,000 0,03180294 0,13395618 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,03180294 0,13372562 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,03180294 0,13349585 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,03180294 0,13326687 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,03180294 0,13303867 ! response to protozoan GO:0001562 13 5 0,000 0,03180294 0,13281125 ! lymph vessel development GO:0001945 10 5 0,000 0,03180294 0,13258461 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,03180294 0,13235874 ! endochondral ossification GO:0001958 17 5 0,000 0,03180294 0,13213364 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,03180294 0,13190931 ! single strand break repair GO:0000012 8 5 0,000 0,03180294 0,13168573 ! parathyroid gland development GO:0060017 14 5 0,000 0,03180294 0,13146292 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,03180294 0,13124085 ! cytokine secretion GO:0050663 15 5 0,000 0,03180294 0,13101953 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,03180294 0,13079896 ! ceramide catabolic process GO:0046514 7 5 0,000 0,03180294 0,13057913 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,03180294 0,13036004 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,03180294 0,13014168 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,03180294 0,12992405 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,03180294 0,12970715 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,03180294 0,12949097 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 0,03180294 0,12927551 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,03180294 0,12906077 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,03180294 0,12884674 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,03180294 0,12863342 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,03180294 0,1284208 ! valine metabolic process GO:0006573 12 5 0,000 0,03180294 0,12820888 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,03180294 0,12799767 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,03180294 0,12778714 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,03180294 0,12757731 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,03180294 0,12736817 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,03180294 0,12715971 ! polyol catabolic process GO:0046174 9 5 0,000 0,03180294 0,12695193 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,03180294 0,12674483 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,03180294 0,12653841 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,03180294 0,12633266 ! mitochondrial fission GO:0000266 8 5 0,000 0,03180294 0,12612757 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,03180294 0,12592315 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,03180294 0,12571939 ! mRNA transcription GO:0009299 10 5 0,000 0,03180294 0,12551629 ! nerve growth factor processing GO:0032455 9 5 0,000 0,03180294 0,12531384 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,03180294 0,12511205 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,03180294 0,12491091 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,03180294 0,12471041 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,03180294 0,12451055 ! monocyte activation GO:0042117 10 5 0,000 0,03180294 0,12431133 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,03180294 0,12411275 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,03180294 0,12391481 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,03180294 0,12371749 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,03180294 0,1235208 ! forebrain neuron development GO:0021884 13 5 0,000 0,03180294 0,12332474 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,03180294 0,12312929 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,03180294 0,12293447 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,03180294 0,12274026 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,03180294 0,12254666 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,03180294 0,12235367 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,03180294 0,12216129 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,03180294 0,12196952 ! lipid glycosylation GO:0030259 7 5 0,000 0,03180294 0,12177834 ! nucleobase transport GO:0015851 6 5 0,000 0,03180294 0,12158777 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,03180294 0,12139779 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,03180294 0,1212084 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,03180294 0,1210196 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,03180294 0,12083139 ! basic amino acid transport GO:0015802 12 5 0,000 0,03180294 0,12064376 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,03180294 0,12045672 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,03180294 0,12027025 ! actin nucleation GO:0045010 11 5 0,000 0,03180294 0,12008436 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,03180294 0,11989905 ! depurination GO:0045007 5 5 0,000 0,03180294 0,1197143 ! depyrimidination GO:0045008 10 5 0,000 0,03180294 0,11953013 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,03180294 0,11934652 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,03180294 0,11916347 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,03180294 0,11898098 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,03180294 0,11879906 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,03180294 0,11861768 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,03180294 0,11843686 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,03180294 0,1182566 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,03180294 0,11807687 ! activated T cell proliferation GO:0050798 16 5 0,000 0,03180294 0,1178977 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,03180294 0,11771907 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,03180294 0,11754097 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,03180294 0,11736342 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,03180294 0,1171864 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,03180294 0,11700991 ! response to arsenic GO:0046685 11 5 0,000 0,03180294 0,11683396 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,03180294 0,11665853 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,03180294 0,11648363 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,03180294 0,11630926 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,03180294 0,1161354 ! response to mercury ion GO:0046689 8 5 0,000 0,03180294 0,11596206 ! response to cadmium ion GO:0046686 7 5 0,000 0,03180294 0,11578924 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,03180294 0,11561694 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,03180294 0,11544515 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,03180294 0,11527386 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,03180294 0,11510309 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,03180294 0,11493282 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,03180294 0,11476305 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,03180294 0,11459378 ! decidualization GO:0046697 11 5 0,000 0,03180294 0,11442501 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,03180294 0,11425674 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,03180294 0,11408896 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,03180294 0,11392168 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,03180294 0,11375488 ! embryonic cleavage GO:0040016 6 5 0,000 0,03180294 0,11358857 ! peroxisome fission GO:0016559 5 5 0,000 0,03180294 0,11342275 ! histone demethylation GO:0016577 13 5 0,000 0,03180294 0,11325741 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,03180294 0,11309255 ! mitotic recombination GO:0006312 9 5 0,000 0,03180294 0,11292817 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,03180294 0,11276427 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,03180294 0,11260085 ! metaphase plate congression GO:0051310 7 5 0,000 0,03180294 0,11243789 ! regulation of sterol transport GO:0032371 7 5 0,000 0,03180294 0,11227541 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,03180294 0,1121134 ! enteric nervous system development GO:0048484 8 5 0,000 0,03180294 0,11195185 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,03180294 0,11179077 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,03180294 0,11163015 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,03180294 0,11146999 ! muscle cell proliferation GO:0033002 12 5 0,000 0,03180294 0,11131029 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,03180294 0,11115105 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,03180294 0,11099226 ! B cell homeostasis GO:0001782 13 5 0,000 0,03180294 0,11083393 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,03180294 0,11067604 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,03180294 0,11051861 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,03180294 0,11036162 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,03180294 0,11020508 ! cellular response to nutrient GO:0031670 8 5 0,000 0,03180294 0,11004898 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,03180294 0,10989333 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,03180294 0,10973811 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,03180294 0,10958333 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,03180294 0,10942899 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,03180294 0,10927508 ! response to redox state GO:0051775 6 5 0,000 0,03180294 0,10912161 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,03180294 0,10896856 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,03180294 0,10881594 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,03180294 0,10866375 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,03180294 0,10851199 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,03180294 0,10836065 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,03180294 0,10820973 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,03180294 0,10805923 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,03180294 0,10790914 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,03180294 0,10775948 ! striatum development GO:0021756 14 5 0,000 0,03180294 0,10761023 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,03180294 0,10746139 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,03180294 0,10731296 ! glial cell migration GO:0008347 10 5 0,000 0,03180294 0,10716494 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,03180294 0,10701733 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,03180294 0,10687013 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,03180294 0,10672333 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,03180294 0,10657693 ! T cell activation during immune response GO:0002286 9 5 0,000 0,03180294 0,10643094 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,03180294 0,10628534 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,03180294 0,10614014 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,03180294 0,10599534 ! neuroprotection GO:0043526 8 5 0,000 0,03180294 0,10585093 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,03180294 0,10570692 ! regulation of sensory perception GO:0051931 8 5 0,000 0,03180294 0,10556329 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,03180294 0,10542006 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,03180294 0,10527721 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,03180294 0,10513475 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,03180294 0,10499268 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,03180294 0,10485099 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,03180294 0,10470968 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,03180294 0,10456875 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,03180294 0,1044282 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,03180294 0,10428803 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,03180294 0,10414823 ! spindle assembly GO:0051225 6 5 0,000 0,03180294 0,10400881 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,03180294 0,10386976 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,03180294 0,10373109 ! protein palmitoylation GO:0018345 12 5 0,000 0,03180294 0,10359278 ! drug metabolic process GO:0017144 7 5 0,000 0,03180294 0,10345484 ! phospholipid scrambling GO:0017121 8 5 0,000 0,03180294 0,10331726 ! organ regeneration GO:0031100 7 5 0,000 0,03180294 0,10318006 ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,03180294 0,10304321 ! hexose transport GO:0008645 68 44 1,000 0,03274475 0,10595422 GO:0015749|monosaccharide transport, ! striated muscle contraction GO:0006941 85 44 1,000 0,03274475 0,10581407 ! double-strand break repair GO:0006302 85 44 1,000 0,03274475 0,10567428 ! B cell differentiation GO:0030183 124 45 1,000 0,03412507 0,10998356 ! developmental growth GO:0048589 88 45 1,000 0,03412507 0,10983865 ! regulation of actin filament polymerization GO:0030833 99 46 1,000 0,03552772 0,11420293 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 1,000 0,03552772 0,11405286 ! polysaccharide biosynthetic process GO:0000271 79 46 1,000 0,03552772 0,11390319 ! cell growth GO:0016049 90 46 1,000 0,03552772 0,1137539 ! positive regulation of protein transport GO:0051222 80 46 1,000 0,03552772 0,11360501 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03804164 0,12148461 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03804164 0,12132601 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,03804164 0,12116783 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,03804164 0,12101006 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03804164 0,1208527 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,03804164 0,12069575 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,03804164 0,1205392 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03804164 0,12038306 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,03804164 0,12022733 ! response to oxygen radical GO:0000305 11 6 0,000 0,03804164 0,120072 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,03804164 0,11991706 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,03804164 0,11976253 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,03804164 0,1196084 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,03804164 0,11945466 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03804164 0,11930132 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03804164 0,11914837 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,03804164 0,11899581 ! forebrain regionalization GO:0021871 9 6 0,000 0,03804164 0,11884364 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03804164 0,11869186 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03804164 0,11854047 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,03804164 0,11838946 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03804164 0,11823884 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,03804164 0,1180886 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,03804164 0,11793874 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03804164 0,11778926 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,03804164 0,11764016 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,03804164 0,11749143 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03804164 0,11734309 ! malate metabolic process GO:0006108 13 6 0,000 0,03804164 0,11719511 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,03804164 0,11704751 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,03804164 0,11690028 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,03804164 0,11675342 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,03804164 0,11660693 ! protein refolding GO:0042026 15 6 0,000 0,03804164 0,11646081 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03804164 0,11631505 ! opsonization GO:0008228 8 6 0,000 0,03804164 0,11616966 ! mating behavior GO:0007617 7 6 0,000 0,03804164 0,11602463 ! erythrocyte maturation GO:0043249 8 6 0,000 0,03804164 0,11587996 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,03804164 0,11573565 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,03804164 0,1155917 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,03804164 0,11544811 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,03804164 0,11530487 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03804164 0,11516199 ! response to interferon-gamma GO:0034341 16 6 0,000 0,03804164 0,11501946 ! toxin metabolic process GO:0009404 11 6 0,000 0,03804164 0,11487729 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03804164 0,11473546 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,03804164 0,11459399 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,03804164 0,11445286 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,03804164 0,11431208 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,03804164 0,11417165 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,03804164 0,11403156 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,03804164 0,11389182 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03804164 0,11375242 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,03804164 0,11361336 ! thymic T cell selection GO:0045061 16 6 0,000 0,03804164 0,11347463 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,03804164 0,11333625 ! protein lipoylation GO:0009249 10 6 0,000 0,03804164 0,1131982 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,03804164 0,11306049 GO:0070633|transepithelial transport, ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03804164 0,11292312 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,03804164 0,11278607 ! glutamate catabolic process GO:0006538 12 6 0,000 0,03804164 0,11264936 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,03804164 0,11251298 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,03804164 0,11237693 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03804164 0,11224121 ! hyperosmotic response GO:0006972 10 6 0,000 0,03804164 0,11210582 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,03804164 0,11197075 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,03804164 0,11183601 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,03804164 0,11170159 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03804164 0,1115675 ! urea metabolic process GO:0019627 7 6 0,000 0,03804164 0,11143372 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03804164 0,11130027 ! neutrophil activation GO:0042119 7 6 0,000 0,03804164 0,11116714 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03804164 0,11103432 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,03804164 0,11090182 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03804164 0,11076964 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,03804164 0,11063777 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,03804164 0,11050621 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03804164 0,11037497 ! neuron apoptosis GO:0051402 15 6 0,000 0,03804164 0,11024404 ! T cell mediated immunity GO:0002456 17 6 0,000 0,03804164 0,11011342 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03804164 0,10998311 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,03804164 0,1098531 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03804164 0,10972341 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,03804164 0,10959402 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,03804164 0,10946493 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,03804164 0,10933615 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,03804164 0,10920767 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03804164 0,10907949 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,03804164 0,10895161 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,03804164 0,10882403 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,03804164 0,10869675 ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,03804164 0,10856977 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,03804164 0,10844309 GO:0045686|negative regulation of glial cell differentiation, ! response to UV-C GO:0010225 14 6 0,000 0,03804164 0,1083167 ! astrocyte development GO:0014002 16 6 0,000 0,03804164 0,1081906 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,03804164 0,1080648 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03804164 0,10793929 ! interaction with symbiont GO:0051702 14 6 0,000 0,03804164 0,10781407 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03804164 0,10768914 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,03804164 0,1075645 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,03804164 0,10744014 ! response to copper ion GO:0046688 10 6 0,000 0,03804164 0,10731608 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,03804164 0,1071923 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,03804164 0,10706881 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03804164 0,1069456 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,03804164 0,10682267 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,03804164 0,10670003 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03804164 0,10657767 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03804164 0,10645558 ! Schwann cell development GO:0014044 15 6 0,000 0,03804164 0,10633378 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,03804164 0,10621226 ! response to pheromone GO:0019236 6 6 0,000 0,03804164 0,10609101 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,03804164 0,10597004 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,03804164 0,10584935 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,03804164 0,10572892 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,03804164 0,10560878 ! subpallium development GO:0021544 15 6 0,000 0,03804164 0,1054889 ! neural tube patterning GO:0021532 8 6 0,000 0,03804164 0,1053693 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,03804164 0,10524997 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,03804164 0,10513091 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03804164 0,10501212 ! G2 phase GO:0051319 16 6 0,000 0,03804164 0,10489359 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,03804164 0,10477534 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,03804164 0,10465735 ! oxygen homeostasis GO:0032364 10 6 0,000 0,03804164 0,10453962 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03804164 0,10442216 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,03804164 0,10430497 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03804164 0,10418803 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,03804164 0,10407136 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03804164 0,10395495 ! receptor internalization GO:0031623 11 6 0,000 0,03804164 0,1038388 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,03804164 0,10372291 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,03804164 0,10360727 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,03804164 0,1034919 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03804164 0,10337678 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,03804164 0,10326192 ! protein deubiquitination GO:0016579 16 6 0,000 0,03804164 0,10314731 ! protein destabilization GO:0031648 9 6 0,000 0,03804164 0,10303295 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,03804164 0,10291885 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03804164 0,10280501 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,03804164 0,10269141 ! regulation of viral transcription GO:0046782 11 6 0,000 0,03804164 0,10257806 ! progesterone metabolic process GO:0042448 12 6 0,000 0,03804164 0,10246497 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,03804164 0,10235212 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,03804164 0,10223952 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,03804164 0,10212717 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03804164 0,10201507 ! determination of adult lifespan GO:0008340 17 6 0,000 0,03804164 0,10190321 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,03804164 0,10179159 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03804164 0,10168022 ! neural plate development GO:0001840 9 6 0,000 0,03804164 0,1015691 ! catecholamine transport GO:0051937 9 6 0,000 0,03804164 0,10145822 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,03804164 0,10134757 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03804164 0,10123717 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,03804164 0,10112701 ! maternal placenta development GO:0001893 12 6 0,000 0,03804164 0,10101709 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,03804164 0,10090741 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03804164 0,10079797 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,03804164 0,10068876 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,03804164 0,10057979 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,03804164 0,10047105 ! mitochondrial transport GO:0006839 94 48 1,000 0,0383987 0,10130457 ! regulation of JAK-STAT cascade GO:0046425 76 48 1,000 0,0383987 0,10119528 ! endosome transport GO:0016197 127 48 1,000 0,0383987 0,10108624 ! positive regulation of DNA binding GO:0043388 83 48 1,000 0,0383987 0,10097743 ! male sex differentiation GO:0046661 93 48 1,000 0,0383987 0,10086885 ! JAK-STAT cascade GO:0007259 82 48 1,000 0,0383987 0,1007605 ! regulation of action potential GO:0001508 102 50 1,000 0,04135499 0,10840155 ! regulation of ossification GO:0030278 123 50 1,000 0,04135499 0,10828536 ! viral infectious cycle GO:0019058 104 51 1,000 0,0428643 0,11211721 ! peptide metabolic process GO:0006518 80 51 1,000 0,0428643 0,1119973 ! response to temperature stimulus GO:0009266 84 51 1,000 0,0428643 0,11187765 ! tRNA transcription GO:0009304 17 7 0,000 0,04424031 0,11534587 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,04424031 0,1152229 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,04424031 0,1151002 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,04424031 0,11497775 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,04424031 0,11485556 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,04424031 0,11473364 ! sleep GO:0030431 16 7 0,000 0,04424031 0,11461197 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,04424031 0,11449056 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,04424031 0,1143694 ! prostate gland development GO:0030850 14 7 0,000 0,04424031 0,1142485 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,04424031 0,11412786 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,04424031 0,11400747 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,04424031 0,11388734 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,04424031 0,11376746 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,04424031 0,11364783 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,04424031 0,11352845 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,04424031 0,11340932 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,04424031 0,11329045 ! glycolipid transport GO:0046836 11 7 0,000 0,04424031 0,11317182 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,04424031 0,11305344 GO:0051923|sulfation, ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,04424031 0,1129353 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,04424031 0,11281742 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,04424031 0,11269978 ! mRNA stabilization GO:0048255 18 7 0,000 0,04424031 0,11258238 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,04424031 0,11246523 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,04424031 0,11234832 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,04424031 0,11223166 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,04424031 0,11211523 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,04424031 0,11199905 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,04424031 0,11188311 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,04424031 0,11176741 ! lipoprotein transport GO:0042953 14 7 0,000 0,04424031 0,11165195 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,04424031 0,11153672 ! rhythmic behavior GO:0007622 17 7 0,000 0,04424031 0,11142174 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,04424031 0,11130699 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,04424031 0,11119247 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,04424031 0,1110782 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,04424031 0,11096415 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,04424031 0,11085034 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,04424031 0,11073677 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,04424031 0,11062342 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,04424031 0,11051031 ! mechanosensory behavior GO:0007638 16 7 0,000 0,04424031 0,11039743 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,04424031 0,11028478 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,04424031 0,11017236 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,04424031 0,11006017 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,04424031 0,1099482 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,04424031 0,10983647 ! spinal cord patterning GO:0021511 14 7 0,000 0,04424031 0,10972496 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,04424031 0,10961368 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,04424031 0,10950262 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,04424031 0,10939179 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,04424031 0,10928118 ! adrenal gland development GO:0030325 17 7 0,000 0,04424031 0,10917079 ! cysteine metabolic process GO:0006534 13 7 0,000 0,04424031 0,10906063 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,04424031 0,10895069 ! ovulation GO:0030728 10 7 0,000 0,04424031 0,10884097 ! adenohypophysis development GO:0021984 11 7 0,000 0,04424031 0,10873147 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,04424031 0,1086222 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,04424031 0,10851314 ! microtubule nucleation GO:0007020 21 7 0,000 0,04424031 0,1084043 ! proline biosynthetic process GO:0006561 10 7 0,000 0,04424031 0,10829568 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,04424031 0,10818727 ! thyroid hormone generation GO:0006590 13 7 0,000 0,04424031 0,10807908 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,04424031 0,10797111 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,04424031 0,10786336 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,04424031 0,10775582 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,04424031 0,10764849 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,04424031 0,10754138 ! galactose metabolic process GO:0006012 13 7 0,000 0,04424031 0,10743448 ! vesicle fusion GO:0006906 20 7 0,000 0,04424031 0,10732779 ! response to dietary excess GO:0002021 8 7 0,000 0,04424031 0,10722131 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,04424031 0,10711505 ! intracellular pH reduction GO:0051452 13 7 0,000 0,04424031 0,10700899 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,04424031 0,10690315 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,04424031 0,10679751 ! organ growth GO:0035265 15 7 0,000 0,04424031 0,10669209 ! nucleoside transport GO:0015858 11 7 0,000 0,04424031 0,10658687 ! nucleoside salvage GO:0043174 11 7 0,000 0,04424031 0,10648186 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,04424031 0,10637705 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,04424031 0,10627245 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,04424031 0,10616806 ! parturition GO:0007567 16 7 0,000 0,04424031 0,10606387 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,04424031 0,10595989 ! rRNA modification GO:0000154 14 7 0,000 0,04424031 0,10585611 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,04424031 0,10575253 ! spindle checkpoint GO:0031577 16 7 0,000 0,04424031 0,10564915 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,04424031 0,10554598 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,04424031 0,10544301 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,04424031 0,10534024 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,04424031 0,10523767 GO:0046676|negative regulation of insulin secretion, ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,04424031 0,1051353 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,04424031 0,10503312 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,04424031 0,10493115 ! eating behavior GO:0042755 8 7 0,000 0,04424031 0,10482937 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,04424031 0,1047278 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,04424031 0,10462641 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,04424031 0,10452523 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,04424031 0,10442424 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,04424031 0,10432344 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,04424031 0,10422284 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,04424031 0,10412243 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,04424031 0,10402222 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,04424031 0,1039222 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,04424031 0,10382237 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,04424031 0,10372273 ! histone ubiquitination GO:0016574 9 7 0,000 0,04424031 0,10362328 ! regulation of meiosis GO:0040020 12 7 0,000 0,04424031 0,10352403 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,04424031 0,10342496 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,04424031 0,10332608 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,04424031 0,1032274 ! membrane to membrane docking GO:0022614 14 7 0,000 0,04424031 0,1031289 ! transcription termination GO:0006353 14 7 0,000 0,04424031 0,10303059 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,04424031 0,10293246 ! anaphase GO:0051322 18 7 0,000 0,04424031 0,10283452 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,04424031 0,10273677 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,04424031 0,10263921 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,04424031 0,10254183 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,04424031 0,10244463 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,04424031 0,10234762 ! diuresis GO:0030146 12 7 0,000 0,04424031 0,10225079 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,04424031 0,10215414 ! thiamin metabolic process GO:0006772 7 7 0,000 0,04424031 0,10205768 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,04424031 0,1019614 ! antibiotic transport GO:0042891 9 7 0,000 0,04424031 0,1018653 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,04424031 0,10176938 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,04424031 0,10167365 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,04424031 0,10157809 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,04424031 0,10148271 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,04424031 0,10138751 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,04424031 0,10129249 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,04424031 0,10119764 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,04424031 0,10110298 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,04424031 0,10100849 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,04424031 0,10091418 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,04424031 0,10082004 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,04424031 0,10072608 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,04424031 0,10063229 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,04424031 0,10053868 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,04424031 0,10044525 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,04424031 0,10035198 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,04424031 0,10025889 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,04424031 0,10016597 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,04424031 0,10007323 ! muscle adaptation GO:0043500 13 7 0,000 0,04424031 0,09998065 ! embryonic heart tube development GO:0035050 14 7 0,000 0,04424031 0,09988825 ! retina homeostasis GO:0001895 12 7 0,000 0,04424031 0,09979602 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,04424031 0,09970395 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,04424031 0,09961206 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,04424031 0,09952034 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,04424031 0,09942878 ! positive regulation of binding GO:0051099 88 52 1,000 0,04439394 0,09968236 ! histone modification GO:0016570 104 52 1,000 0,04439394 0,09959082 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 1,000 0,04594361 0,10297269 ! embryonic skeletal system development GO:0048706 101 54 1,000 0,04751297 0,10639248 ! membrane fusion GO:0006944 122 54 1,000 0,04751297 0,10629505 ! covalent chromatin modification GO:0016569 115 54 1,000 0,04751297 0,1061978 ! regulation of cell shape GO:0008360 142 54 1,000 0,04751297 0,10610072 ! activation of phospholipase C activity GO:0007202 110 54 1,000 0,04751297 0,10600383 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 0,04910172 0,10944845 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 1,000 0,04910172 0,10934868 ! cell recognition GO:0008037 98 55 1,000 0,04910172 0,10924909 ! regulation of multicellular organism growth GO:0040014 90 55 1,000 0,04910172 0,10914968 ! regulation of protein polymerization GO:0032271 117 55 1,000 0,04910172 0,10905046 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,05039922 0,11183042 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,05039922 0,11172894 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,05039922 0,11162764 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,05039922 0,11152653 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,05039922 0,1114256 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,05039922 0,11132485 ! male meiosis GO:0007140 9 8 0,000 0,05039922 0,11122429 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,05039922 0,11112391 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,05039922 0,1110237 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,05039922 0,11092368 ! meiotic prophase I GO:0007128 14 8 0,000 0,05039922 0,11082384 ! response to zinc ion GO:0010043 12 8 0,000 0,05039922 0,11072418 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,05039922 0,1106247 ! oligopeptide transport GO:0006857 16 8 0,000 0,05039922 0,11052539 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,05039922 0,11042627 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,05039922 0,11032732 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,05039922 0,11022855 ! signal peptide processing GO:0006465 12 8 0,000 0,05039922 0,11012995 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,05039922 0,11003153 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,05039922 0,10993329 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,05039922 0,10983522 ! succinate metabolic process GO:0006105 17 8 0,000 0,05039922 0,10973733 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,05039922 0,10963961 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,05039922 0,10954207 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,05039922 0,1094447 ! estrogen metabolic process GO:0008210 17 8 0,000 0,05039922 0,1093475 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,05039922 0,10925048 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,05039922 0,10915362 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,05039922 0,10905694 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,05039922 0,10896043 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,05039922 0,10886409 ! reflex GO:0060004 17 8 0,000 0,05039922 0,10876792 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,05039922 0,10867192 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,05039922 0,10857609 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,05039922 0,10848043 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,05039922 0,10838494 ! pigment granule organization GO:0048753 17 8 0,000 0,05039922 0,10828961 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,05039922 0,10819445 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,05039922 0,10809946 ! astrocyte differentiation GO:0048708 19 8 0,000 0,05039922 0,10800464 ! histidine catabolic process GO:0006548 10 8 0,000 0,05039922 0,10790998 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,05039922 0,10781549 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,05039922 0,10772116 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,05039922 0,107627 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,05039922 0,107533 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,05039922 0,10743917 ! melanin metabolic process GO:0006582 17 8 0,000 0,05039922 0,1073455 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,05039922 0,10725199 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,05039922 0,10715865 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,05039922 0,10706547 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,05039922 0,10697245 ! macrophage activation GO:0042116 13 8 0,000 0,05039922 0,10687959 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,05039922 0,10678689 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,05039922 0,10669436 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,05039922 0,10660198 ! purine salvage GO:0043101 12 8 0,000 0,05039922 0,10650976 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,05039922 0,10641771 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,05039922 0,10632581 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,05039922 0,10623407 ! osteoblast development GO:0002076 17 8 0,000 0,05039922 0,10614249 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,05039922 0,10605107 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,05039922 0,1059598 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,05039922 0,10586869 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,05039922 0,10577774 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,05039922 0,10568694 ! response to UV-B GO:0010224 17 8 0,000 0,05039922 0,1055963 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,05039922 0,10550582 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,05039922 0,10541549 ! intermediate filament organization GO:0045109 12 8 0,000 0,05039922 0,10532531 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,05039922 0,10523529 ! cellular extravasation GO:0045123 13 8 0,000 0,05039922 0,10514542 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,05039922 0,10505571 ! response to antibiotic GO:0046677 11 8 0,000 0,05039922 0,10496614 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,05039922 0,10487674 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,05039922 0,10478748 ! response to tropane GO:0014073 15 8 0,000 0,05039922 0,10469837 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,05039922 0,10460942 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,05039922 0,10452062 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,05039922 0,10443197 ! mast cell activation GO:0045576 14 8 0,000 0,05039922 0,10434346 ! multicellular organismal aging GO:0010259 20 8 0,000 0,05039922 0,10425511 ! gas homeostasis GO:0033483 14 8 0,000 0,05039922 0,10416691 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,05039922 0,10407886 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,05039922 0,10399095 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,05039922 0,1039032 ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,05039922 0,10381559 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,05039922 0,10372813 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,05039922 0,10364081 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,05039922 0,10355365 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,05039922 0,10346663 ! intracellular lipid transport GO:0032365 16 8 0,000 0,05039922 0,10337975 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,05039922 0,10329303 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,05039922 0,10320644 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,05039922 0,10312001 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,05039922 0,10303371 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,05039922 0,10294756 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,05039922 0,10286156 ! hormone catabolic process GO:0042447 17 8 0,000 0,05039922 0,1027757 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,05039922 0,10268998 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,05039922 0,10260441 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,05039922 0,10251897 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,05039922 0,10243368 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,05039922 0,10234853 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,05039922 0,10226353 ! adult feeding behavior GO:0008343 10 8 0,000 0,05039922 0,10217866 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,05039922 0,10209394 ! ATP catabolic process GO:0006200 11 8 0,000 0,05039922 0,10200935 ! blastocyst growth GO:0001832 19 8 0,000 0,05039922 0,10192491 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,05039922 0,1018406 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,05039922 0,10175644 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,05039922 0,10167241 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,05039922 0,10158852 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,05039922 0,10150477 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,05039922 0,10142116 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,05039922 0,10133768 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,05039922 0,10125435 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,05039922 0,10117115 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,05039922 0,10108808 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,05039922 0,10100516 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,05039922 0,10092237 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,05039922 0,10083971 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,05039922 0,10075719 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,05039922 0,10067481 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,05039922 0,10059255 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,05039922 0,10051044 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,05039922 0,10042846 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,05039922 0,10034661 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,05039922 0,10026489 ! chloride transport GO:0006821 102 57 1,000 0,05233612 0,10403347 ! regulation of bone remodeling GO:0046850 143 57 1,000 0,05233612 0,10394889 ! regulation of phospholipase activity GO:0010517 113 57 1,000 0,05233612 0,10386445 ! heart morphogenesis GO:0003007 105 57 1,000 0,05233612 0,10378014 ! nucleotide-excision repair GO:0006289 91 57 1,000 0,05233612 0,10369597 ! regulation of intracellular transport GO:0032386 108 57 1,000 0,05233612 0,10361194 ! regulation of actin filament length GO:0030832 118 58 1,000 0,05398115 0,10678215 ! gastrulation GO:0007369 122 58 1,000 0,05398115 0,10669576 ! regulation of tissue remodeling GO:0034103 146 58 1,000 0,05398115 0,1066095 ! positive regulation of organelle organization GO:0010638 108 58 1,000 0,05398115 0,10652339 ! positive regulation of lipase activity GO:0060193 115 58 1,000 0,05398115 0,10643741 ! maintenance of location GO:0051235 124 58 1,000 0,05398115 0,10635158 ! axon extension GO:0048675 16 9 0,000 0,05651861 0,11126104 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,05651861 0,11117146 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,05651861 0,11108202 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,05651861 0,11099273 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,05651861 0,11090358 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,05651861 0,11081457 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,05651861 0,1107257 ! reproductive behavior GO:0019098 22 9 0,000 0,05651861 0,11063698 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,05651861 0,1105484 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,05651861 0,11045996 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,05651861 0,11037166 ! UTP metabolic process GO:0046051 10 9 0,000 0,05651861 0,11028351 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,05651861 0,11019549 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,05651861 0,11010762 ! artery development GO:0060840 25 9 0,000 0,05651861 0,11001988 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,05651861 0,10993229 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,05651861 0,10984483 ! equilibrioception GO:0050957 20 9 0,000 0,05651861 0,10975751 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,05651861 0,10967034 ! chemosensory behavior GO:0007635 21 9 0,000 0,05651861 0,1095833 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,05651861 0,10949639 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,05651861 0,10940963 ! leukocyte degranulation GO:0043299 16 9 0,000 0,05651861 0,109323 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,05651861 0,10923651 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,05651861 0,10915016 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,05651861 0,10906394 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,05651861 0,10897786 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,05651861 0,10889192 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,05651861 0,10880611 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,05651861 0,10872044 ! protein targeting to ER GO:0045047 25 9 0,000 0,05651861 0,1086349 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,05651861 0,10854949 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,05651861 0,10846422 ! T cell selection GO:0045058 27 9 0,000 0,05651861 0,10837908 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,05651861 0,10829408 ! glycine catabolic process GO:0006546 15 9 0,000 0,05651861 0,10820921 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,05651861 0,10812447 ! endosome organization GO:0007032 20 9 0,000 0,05651861 0,10803987 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,05651861 0,1079554 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,05651861 0,10787106 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,05651861 0,10778685 ! mannose metabolic process GO:0006013 13 9 0,000 0,05651861 0,10770277 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,05651861 0,10761882 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,05651861 0,10753501 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,05651861 0,10745132 ! receptor clustering GO:0043113 20 9 0,000 0,05651861 0,10736777 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,05651861 0,10728435 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,05651861 0,10720105 ! retinol metabolic process GO:0042572 20 9 0,000 0,05651861 0,10711788 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,05651861 0,10703485 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,05651861 0,10695194 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,05651861 0,10686916 ! macrophage differentiation GO:0030225 15 9 0,000 0,05651861 0,10678651 ! oligodendrocyte development GO:0014003 11 9 0,000 0,05651861 0,10670398 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,05651861 0,10662158 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,05651861 0,10653932 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,05651861 0,10645717 ! response to amine stimulus GO:0014075 13 9 0,000 0,05651861 0,10637516 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,05651861 0,10629327 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,05651861 0,1062115 ! erythrocyte development GO:0048821 17 9 0,000 0,05651861 0,10612986 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,05651861 0,10604835 ! renal water homeostasis GO:0003091 15 9 0,000 0,05651861 0,10596696 ! postreplication repair GO:0006301 25 9 0,000 0,05651861 0,1058857 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,05651861 0,10580456 ! icosanoid secretion GO:0032309 15 9 0,000 0,05651861 0,10572355 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,05651861 0,10564266 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,05651861 0,10556189 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,05651861 0,10548125 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,05651861 0,10540073 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,05651861 0,10532033 ! sterol catabolic process GO:0016127 14 9 0,000 0,05651861 0,10524006 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,05651861 0,1051599 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,05651861 0,10507987 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,05651861 0,10499996 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,05651861 0,10492018 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,05651861 0,10484051 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,05651861 0,10476097 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,05651861 0,10468154 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,05651861 0,10460224 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,05651861 0,10452305 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,05651861 0,10444399 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,05651861 0,10436504 ! purine base metabolic process GO:0006144 25 9 0,000 0,05651861 0,10428622 ! pigment granule transport GO:0051904 17 9 0,000 0,05651861 0,10420751 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,05651861 0,10412892 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,05651861 0,10405045 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,05651861 0,1039721 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,05651861 0,10389387 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,05651861 0,10381575 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,05651861 0,10373776 ! mitochondrion localization GO:0051646 18 9 0,000 0,05651861 0,10365987 ! DNA catabolic process GO:0006308 94 60 1,000 0,05732538 0,1050607 ! heterocycle catabolic process GO:0046700 100 60 1,000 0,05732538 0,10498194 ! kidney development GO:0001822 133 60 1,000 0,05732538 0,1049033 ! regulation of cellular component size GO:0032535 125 61 1,000 0,05902398 0,10793082 ! cytokine-mediated signaling pathway GO:0019221 112 61 1,000 0,05902398 0,1078501 ! camera-type eye development GO:0043010 126 61 1,000 0,05902398 0,10776949 ! DNA damage response, signal transduction GO:0042770 136 62 1,000 0,06073984 0,11081958 ! nucleoside metabolic process GO:0009116 91 62 1,000 0,06073984 0,11073688 ! regulation of protein complex assembly GO:0043254 132 63 1,000 0,06247267 0,11381113 ! regulation of mitosis GO:0007088 112 63 1,000 0,06247267 0,11372632 GO:0051783|regulation of nuclear division, ! skeletal system morphogenesis GO:0048705 118 63 1,000 0,06247267 0,11364164 ! water-soluble vitamin metabolic process GO:0006767 107 63 1,000 0,06247267 0,11355709 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,06259873 0,11370163 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,06259873 0,11361716 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,06259873 0,11353281 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,06259873 0,11344859 ! associative learning GO:0008306 21 10 0,000 0,06259873 0,11336449 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,06259873 0,11328052 ! phosphate transport GO:0006817 24 10 0,000 0,06259873 0,11319667 ! cell volume homeostasis GO:0006884 17 10 0,000 0,06259873 0,11311294 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,06259873 0,11302934 ! CTP metabolic process GO:0046036 11 10 0,000 0,06259873 0,11294586 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,06259873 0,11286251 ! GTP metabolic process GO:0046039 11 10 0,000 0,06259873 0,11277928 ! social behavior GO:0035176 29 10 0,000 0,06259873 0,11269617 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,06259873 0,11261318 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,06259873 0,11253031 ! androgen metabolic process GO:0008209 17 10 0,000 0,06259873 0,11244757 ! phospholipid efflux GO:0033700 19 10 0,000 0,06259873 0,11236495 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,06259873 0,11228245 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,06259873 0,11220007 ! lung alveolus development GO:0048286 26 10 0,000 0,06259873 0,11211781 ! pathogenesis GO:0009405 17 10 0,000 0,06259873 0,11203568 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,06259873 0,11195366 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,06259873 0,11187176 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,06259873 0,11178998 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,06259873 0,11170833 ! endoderm development GO:0007492 18 10 0,000 0,06259873 0,11162679 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,06259873 0,11154537 ! arginine catabolic process GO:0006527 17 10 0,000 0,06259873 0,11146407 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,06259873 0,11138288 ! proline metabolic process GO:0006560 13 10 0,000 0,06259873 0,11130182 ! phosphagen metabolic process GO:0006599 17 10 0,000 0,06259873 0,11122087 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,06259873 0,11114004 ! V(D)J recombination GO:0033151 34 10 0,000 0,06259873 0,11105933 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,06259873 0,11097874 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,06259873 0,11089826 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,06259873 0,1108179 ! B cell proliferation GO:0042100 19 10 0,000 0,06259873 0,11073765 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,06259873 0,11065752 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,06259873 0,11057751 ! multicellular organism growth GO:0035264 19 10 0,000 0,06259873 0,11049761 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,06259873 0,11041783 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,06259873 0,11033817 ! ruffle organization GO:0031529 17 10 0,000 0,06259873 0,11025861 ! epithelial cell development GO:0002064 21 10 0,000 0,06259873 0,11017918 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,06259873 0,11009985 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,06259873 0,11002065 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,06259873 0,10994155 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,06259873 0,10986257 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,06259873 0,1097837 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,06259873 0,10970495 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 13 10 0,000 0,06259873 0,10962631 ! regulation of bone resorption GO:0045124 25 10 0,000 0,06259873 0,10954778 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,06259873 0,10946936 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,06259873 0,10939106 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,06259873 0,10931286 ! segment specification GO:0007379 15 10 0,000 0,06259873 0,10923478 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,06259873 0,10915681 ! blastoderm segmentation GO:0007350 19 10 0,000 0,06259873 0,10907896 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,06259873 0,10900121 ! response to dsRNA GO:0043331 23 10 0,000 0,06259873 0,10892357 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,06259873 0,10884605 ! melanosome localization GO:0032400 16 10 0,000 0,06259873 0,10876863 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,06259873 0,10869133 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,06259873 0,10861413 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,06259873 0,10853705 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,06259873 0,10846007 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,06259873 0,1083832 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,06259873 0,10830644 ! protein sumoylation GO:0016925 17 10 0,000 0,06259873 0,10822979 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,06259873 0,10815325 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,06259873 0,10807682 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,06259873 0,10800049 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,06259873 0,10792427 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,06259873 0,10784816 ! salivary gland development GO:0007431 28 10 0,000 0,06259873 0,10777216 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,06259873 0,10769627 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,06259873 0,10762048 ! midbrain development GO:0030901 14 10 0,000 0,06259873 0,10754479 ! musculoskeletal movement GO:0050881 16 10 0,000 0,06259873 0,10746922 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,06259873 0,10739375 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,06259873 0,10731838 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,06259873 0,10724313 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,06259873 0,10716797 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,06259873 0,10709293 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,06259873 0,10701798 ! detection of calcium ion GO:0005513 24 10 0,000 0,06259873 0,10694315 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,06259873 0,10686841 ! blastocyst formation GO:0001825 18 10 0,000 0,06259873 0,10679378 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,06259873 0,10671926 ! cerebellar cortex development GO:0021695 16 10 0,000 0,06259873 0,10664484 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,06259873 0,10657052 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,06259873 0,10649631 ! response to nicotine GO:0035094 20 10 0,000 0,06259873 0,1064222 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,06259873 0,10634819 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,06259873 0,10627429 ! regulation of lipid metabolic process GO:0019216 132 66 1,000 0,06777012 0,1149739 ! gonad development GO:0008406 115 66 1,000 0,06777012 0,11489411 ! steroid hormone receptor signaling pathway GO:0030518 146 66 1,000 0,06777012 0,11481443 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,06863984 0,1162073 ! respiratory burst GO:0045730 17 11 0,000 0,06863984 0,11612683 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,06863984 0,11604646 ! neuron fate specification GO:0048665 18 11 0,000 0,06863984 0,11596621 ! telencephalon cell migration GO:0022029 23 11 0,000 0,06863984 0,11588606 ! thyroid gland development GO:0030878 26 11 0,000 0,06863984 0,11580603 ! synapsis GO:0007129 14 11 0,000 0,06863984 0,11572611 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,06863984 0,1156463 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,06863984 0,1155666 ! response to pain GO:0048265 27 11 0,000 0,06863984 0,11548701 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,06863984 0,11540753 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,06863984 0,11532815 ! blood vessel remodeling GO:0001974 30 11 0,000 0,06863984 0,11524889 ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,06863984 0,11516974 ! bone resorption GO:0045453 16 11 0,000 0,06863984 0,11509069 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,06863984 0,11501175 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,06863984 0,11493292 ! melanocyte differentiation GO:0030318 20 11 0,000 0,06863984 0,1148542 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,06863984 0,11477559 GO:0009075|histidine family amino acid metabolic process, ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,06863984 0,11469708 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,06863984 0,11461868 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,06863984 0,11454039 ! UV protection GO:0009650 20 11 0,000 0,06863984 0,11446221 ! adult heart development GO:0007512 16 11 0,000 0,06863984 0,11438413 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,06863984 0,11430616 ! macroautophagy GO:0016236 19 11 0,000 0,06863984 0,11422829 ! temperature homeostasis GO:0001659 18 11 0,000 0,06863984 0,11415053 ! behavioral fear response GO:0001662 27 11 0,000 0,06863984 0,11407288 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,06863984 0,11399533 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,06863984 0,11391789 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,06863984 0,11384055 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,06863984 0,11376332 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,06863984 0,11368619 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,06863984 0,11360917 ! regulation of organ growth GO:0046620 14 11 0,000 0,06863984 0,11353225 ! pigment granule localization GO:0051875 20 11 0,000 0,06863984 0,11345544 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,06863984 0,11337873 ! vasoconstriction GO:0042310 20 11 0,000 0,06863984 0,11330212 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,06863984 0,11322561 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,06863984 0,11314921 ! embryonic axis specification GO:0000578 19 11 0,000 0,06863984 0,11307292 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,06863984 0,11299672 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,06863984 0,11292063 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,06863984 0,11284464 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,06863984 0,11276875 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,06863984 0,11269297 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,06863984 0,11261728 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,06863984 0,1125417 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,06863984 0,11246622 ! prophase GO:0051324 17 11 0,000 0,06863984 0,11239084 ! neuroblast proliferation GO:0007405 25 11 0,000 0,06863984 0,11231556 ! nucleosome positioning GO:0016584 15 11 0,000 0,06863984 0,11224039 ! regulation of isotype switching GO:0045191 24 11 0,000 0,06863984 0,11216531 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,06863984 0,11209033 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,06863984 0,11201545 ! acid secretion GO:0046717 20 11 0,000 0,06863984 0,11194068 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,06863984 0,111866 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,06863984 0,11179142 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,06863984 0,11171695 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,06863984 0,11164257 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,06863984 0,11156829 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,06863984 0,11149411 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,06863984 0,11142002 ! cholesterol efflux GO:0033344 21 11 0,000 0,06863984 0,11134604 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,06863984 0,11127215 ! oocyte development GO:0048599 20 11 0,000 0,06863984 0,11119837 ! germ cell migration GO:0008354 26 11 0,000 0,06863984 0,11112468 ! embryonic gut development GO:0048566 19 11 0,000 0,06863984 0,11105108 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,06863984 0,11097759 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,06863984 0,11090419 ! activation of innate immune response GO:0002218 16 11 0,000 0,06863984 0,11083089 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,06863984 0,11075769 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,06863984 0,11068458 ! lysogeny GO:0030069 22 11 0,000 0,06863984 0,11061157 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,06863984 0,11053865 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,06863984 0,11046583 ! sequestering of metal ion GO:0051238 15 11 0,000 0,06863984 0,11039311 ! nucleus localization GO:0051647 22 11 0,000 0,06863984 0,11032048 ! activation of MAPK activity GO:0000187 124 67 1,000 0,06956799 0,11173873 ! myeloid cell differentiation GO:0030099 126 67 1,000 0,06956799 0,11166531 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 1,000 0,07138142 0,11450086 ! negative regulation of ligase activity GO:0051352 116 68 1,000 0,07138142 0,11442573 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! positive regulation of T cell activation GO:0050870 124 68 1,000 0,07138142 0,1143507 ! regulation of lipase activity GO:0060191 137 68 1,000 0,07138142 0,11427576 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 1,000 0,07138142 0,11420093 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 1,000 0,07321014 0,11704999 ! urogenital system development GO:0001655 149 69 1,000 0,07321014 0,11697343 ! homeostasis of number of cells GO:0048872 131 69 1,000 0,07321014 0,11689698 ! developmental maturation GO:0021700 128 69 1,000 0,07321014 0,11682063 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,07464219 0,11902799 ! mating GO:0007618 17 12 0,000 0,07464219 0,11895034 ! protein complex disassembly GO:0043241 28 12 0,000 0,07464219 0,1188728 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,07464219 0,11879536 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,07464219 0,11871802 ! hippocampus development GO:0021766 29 12 0,000 0,07464219 0,11864078 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,07464219 0,11856364 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,07464219 0,1184866 ! T cell proliferation GO:0042098 32 12 0,000 0,07464219 0,11840966 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,07464219 0,11833282 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,07464219 0,11825608 ! ventral spinal cord development GO:0021517 25 12 0,000 0,07464219 0,11817944 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,07464219 0,1181029 ! drug transport GO:0015893 16 12 0,000 0,07464219 0,11802646 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,07464219 0,11795011 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,07464219 0,11787387 ! polyamine metabolic process GO:0006595 18 12 0,000 0,07464219 0,11779772 ! focal adhesion formation GO:0048041 37 12 0,000 0,07464219 0,11772168 ! mitotic spindle organization GO:0007052 23 12 0,000 0,07464219 0,11764573 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,07464219 0,11756987 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,07464219 0,11749412 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,07464219 0,11741846 ! lipid digestion GO:0044241 21 12 0,000 0,07464219 0,11734291 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,07464219 0,11726744 ! entry into host cell GO:0030260 34 12 0,000 0,07464219 0,11719208 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,07464219 0,11711681 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,07464219 0,11704164 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,07464219 0,11696656 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,07464219 0,11689159 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,07464219 0,1168167 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,07464219 0,11674192 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,07464219 0,11666723 ! snRNA metabolic process GO:0016073 30 12 0,000 0,07464219 0,11659263 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,07464219 0,11651813 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,07464219 0,11644373 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,07464219 0,11636942 ! fucose catabolic process GO:0019317 25 12 0,000 0,07464219 0,1162952 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,07464219 0,11622108 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,07464219 0,11614705 ! zymogen activation GO:0031638 18 12 0,000 0,07464219 0,11607312 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,07464219 0,11599928 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,07464219 0,11592554 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,07464219 0,11585189 ! oocyte differentiation GO:0009994 21 12 0,000 0,07464219 0,11577833 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,07464219 0,11570487 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,07464219 0,1156315 ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,07464219 0,11555822 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,07464219 0,11548504 ! defense response to fungus GO:0050832 15 12 0,000 0,07464219 0,11541195 ! embryonic placenta development GO:0001892 21 12 0,000 0,07464219 0,11533895 ! lamellipodium assembly GO:0030032 24 12 0,000 0,07464219 0,11526604 ! response to cold GO:0009409 17 12 0,000 0,07464219 0,11519322 ! regulation of synapse organization GO:0050807 18 12 0,000 0,07464219 0,1151205 ! cAMP-mediated signaling GO:0019933 124 71 1,000 0,07691237 0,11854696 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 1,000 0,07691237 0,11847221 ! carbohydrate transport GO:0008643 114 72 1,000 0,07878535 0,12128079 ! actin filament organization GO:0007015 167 72 1,000 0,07878535 0,12120442 ! B cell activation GO:0042113 179 72 1,000 0,07878535 0,12112814 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 1,000 0,07878535 0,12105196 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 1,000 0,07878535 0,12097587 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,08060603 0,12369379 ! cGMP metabolic process GO:0046068 18 13 0,000 0,08060603 0,12361615 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,08060603 0,12353859 ! regulation of chemokine production GO:0032642 18 13 0,000 0,08060603 0,12346114 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,08060603 0,12338378 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,08060603 0,12330652 ! peroxisomal transport GO:0043574 28 13 0,000 0,08060603 0,12322936 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,08060603 0,1231523 ! cartilage condensation GO:0001502 22 13 0,000 0,08060603 0,12307533 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,08060603 0,12299845 ! organelle fusion GO:0048284 36 13 0,000 0,08060603 0,12292167 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,08060603 0,12284499 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,08060603 0,1227684 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,08060603 0,12269191 ! endocrine pancreas development GO:0031018 25 13 0,000 0,08060603 0,12261552 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,08060603 0,12253922 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,08060603 0,12246301 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,08060603 0,1223869 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,08060603 0,12231088 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,08060603 0,12223496 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,08060603 0,12215913 ! methionine metabolic process GO:0006555 31 13 0,000 0,08060603 0,1220834 ! plasma membrane organization GO:0007009 27 13 0,000 0,08060603 0,12200776 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,08060603 0,12193221 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,08060603 0,12185676 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,08060603 0,1217814 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,08060603 0,12170613 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! cytokine metabolic process GO:0042107 24 13 0,000 0,08060603 0,12163096 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,08060603 0,12155588 ! exocrine system development GO:0035272 34 13 0,000 0,08060603 0,12148089 ! monoamine transport GO:0015844 21 13 0,000 0,08060603 0,12140599 ! L-glutamate transport GO:0015813 30 13 0,000 0,08060603 0,12133119 GO:0015800|acidic amino acid transport, ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,08060603 0,12125648 ! protein homotetramerization GO:0051289 24 13 0,000 0,08060603 0,12118186 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,08060603 0,12110733 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,08060603 0,1210329 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,08060603 0,12095855 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,08060603 0,1208843 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,08060603 0,12081014 ! histone methylation GO:0016571 29 13 0,000 0,08060603 0,12073606 ! chromatin silencing GO:0006342 29 13 0,000 0,08060603 0,12066208 ! gland morphogenesis GO:0022612 31 13 0,000 0,08060603 0,12058819 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,08060603 0,12051439 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,08060603 0,12044069 ! regulation of epidermis development GO:0045682 19 13 0,000 0,08060603 0,12036707 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,08060603 0,12029354 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,08060603 0,1202201 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,08060603 0,12014675 ! spleen development GO:0048536 24 13 0,000 0,08060603 0,12007349 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,08060603 0,12000032 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,08060603 0,11992724 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,08060603 0,11985424 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,08060603 0,11978134 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,08060603 0,11970852 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,08060603 0,1196358 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,08060603 0,11956316 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,08060603 0,11949061 ! insulin secretion GO:0030073 24 13 0,000 0,08060603 0,11941814 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,08060603 0,11934577 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,08060603 0,11927348 ! acrosome reaction GO:0007340 19 13 0,000 0,08060603 0,11920128 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,08060603 0,11912917 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,08060603 0,11905715 ! amino acid transport GO:0006865 148 74 1,000 0,08257372 0,12188979 ! transition metal ion transport GO:0000041 143 75 1,000 0,0844886 0,1246411 ! reproductive structure development GO:0048608 131 75 1,000 0,0844886 0,12456588 ! eye development GO:0001654 155 75 1,000 0,0844886 0,12449075 ! cell-matrix adhesion GO:0007160 181 76 1,000 0,08641694 0,12725532 ! regulation of actin cytoskeleton organization GO:0032956 167 76 1,000 0,08641694 0,12717866 ! lymphocyte differentiation GO:0030098 193 76 1,000 0,08641694 0,1271021 ! rRNA transcription GO:0009303 28 14 0,000 0,08653159 0,12719415 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,08653159 0,12711766 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,08653159 0,12704127 ! water transport GO:0006833 21 14 0,000 0,08653159 0,12696497 GO:0042044|fluid transport, ! non-recombinational repair GO:0000726 29 14 0,000 0,08653159 0,12688876 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,08653159 0,12681264 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,08653159 0,12673661 ! palate development GO:0060021 32 14 0,000 0,08653159 0,12666068 ! regulated secretory pathway GO:0045055 24 14 0,000 0,08653159 0,12658483 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,08653159 0,12650908 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,08653159 0,12643342 ! arginine metabolic process GO:0006525 21 14 0,000 0,08653159 0,12635784 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,08653159 0,12628236 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,08653159 0,12620697 ! regulation of heart rate GO:0002027 25 14 0,000 0,08653159 0,12613167 ! fear response GO:0042596 34 14 0,000 0,08653159 0,12605645 ! organic alcohol transport GO:0015850 29 14 0,000 0,08653159 0,12598133 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,08653159 0,1259063 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,08653159 0,12583135 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,08653159 0,1257565 ! neutral amino acid transport GO:0015804 28 14 0,000 0,08653159 0,12568173 ! bone mineralization GO:0030282 18 14 0,000 0,08653159 0,12560706 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,08653159 0,12553247 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,08653159 0,12545797 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,08653159 0,12538355 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,08653159 0,12530923 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,08653159 0,125235 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,08653159 0,12516085 ! ribosome assembly GO:0042255 18 14 0,000 0,08653159 0,12508679 ! cerebellum development GO:0021549 23 14 0,000 0,08653159 0,12501282 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,08653159 0,12493893 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,08653159 0,12486514 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,08653159 0,12479142 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,08653159 0,1247178 ! NADP metabolic process GO:0006739 24 14 0,000 0,08653159 0,12464427 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,08653159 0,12457082 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,08653159 0,12449745 ! male genitalia development GO:0030539 26 14 0,000 0,08653159 0,12442418 ! regulation of axon extension GO:0030516 43 14 0,000 0,08653159 0,12435098 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,08653159 0,12427788 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,08653159 0,12420486 ! positive regulation of ligase activity GO:0051351 130 77 1,000 0,08835848 0,12675265 ! regulation of actin filament-based process GO:0032970 170 79 1,000 0,09228018 0,13230076 ! regulation of synaptic transmission GO:0050804 159 79 1,000 0,09228018 0,13222316 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,09241913 0,13234463 ! lactation GO:0007595 30 15 0,000 0,09241913 0,1322671 ! reproductive cellular process GO:0048610 22 15 0,000 0,09241913 0,13218966 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,09241913 0,13211231 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,09241913 0,13203505 ! superoxide anion generation GO:0042554 22 15 0,000 0,09241913 0,13195788 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,09241913 0,1318808 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,09241913 0,13180381 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,09241913 0,13172691 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,09241913 0,13165011 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,09241913 0,13157339 ! sulfate transport GO:0008272 27 15 0,000 0,09241913 0,13149676 ! response to cAMP GO:0051591 25 15 0,000 0,09241913 0,13142022 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,09241913 0,13134376 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,09241913 0,1312674 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,09241913 0,13119113 ! response to hexose stimulus GO:0009746 25 15 0,000 0,09241913 0,13111494 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,09241913 0,13103885 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,09241913 0,13096284 ! vesicle coating GO:0006901 38 15 0,000 0,09241913 0,13088692 ! regulation of exocytosis GO:0017157 26 15 0,000 0,09241913 0,13081108 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,09241913 0,13073534 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,09241913 0,13065968 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,09241913 0,13058411 ! regulation of vasodilation GO:0042312 27 15 0,000 0,09241913 0,13050863 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,09241913 0,13043324 ! histone deacetylation GO:0016575 24 15 0,000 0,09241913 0,13035793 ! water homeostasis GO:0030104 28 15 0,000 0,09241913 0,13028271 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,09241913 0,13020757 ! muscle maintenance GO:0046716 26 15 0,000 0,09241913 0,13013253 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,09241913 0,13005756 ! intestinal absorption GO:0050892 31 15 0,000 0,09241913 0,12998269 ! dopamine metabolic process GO:0042417 35 15 0,000 0,09241913 0,1299079 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,09241913 0,1298332 ! heme biosynthetic process GO:0006783 33 15 0,000 0,09241913 0,12975858 ! cell killing GO:0001906 32 15 0,000 0,09241913 0,12968405 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,09241913 0,1296096 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,09241913 0,12953524 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,09241913 0,12946097 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,09241913 0,12938678 ! actin filament polymerization GO:0030041 27 15 0,000 0,09241913 0,12931268 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,09241913 0,12923866 ! development of primary sexual characteristics GO:0045137 143 80 1,000 0,09425986 0,13173732 ! cell-substrate adhesion GO:0031589 189 82 1,000 0,09825565 0,13724332 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,09826889 0,13718336 ! positive regulation of cell size GO:0045793 29 16 0,000 0,09826889 0,13710502 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,09826889 0,13702676 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,09826889 0,1369486 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,09826889 0,13687052 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,09826889 0,13679253 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,09826889 0,13671463 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,09826889 0,13663682 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,09826889 0,13655909 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,09826889 0,13648146 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,09826889 0,13640391 ! startle response GO:0001964 28 16 0,000 0,09826889 0,13632646 ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,09826889 0,13624909 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,09826889 0,1361718 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,09826889 0,13609461 ! protein polyubiquitination GO:0000209 41 16 0,000 0,09826889 0,1360175 ! glutamate metabolic process GO:0006536 25 16 0,000 0,09826889 0,13594048 ! pituitary gland development GO:0021983 30 16 0,000 0,09826889 0,13586355 ! response to osmotic stress GO:0006970 27 16 0,000 0,09826889 0,1357867 ! lysosomal transport GO:0007041 31 16 0,000 0,09826889 0,13570994 ! fructose metabolic process GO:0006000 25 16 0,000 0,09826889 0,13563327 ! L-amino acid transport GO:0015807 33 16 0,000 0,09826889 0,13555668 ! stem cell development GO:0048864 46 16 0,000 0,09826889 0,13548019 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,09826889 0,13540377 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,09826889 0,13532745 ! negative regulation of immune response GO:0050777 38 16 0,000 0,09826889 0,1352512 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,09826889 0,13517505 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,09826889 0,13509898 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,09826889 0,135023 ! mRNA splice site selection GO:0006376 44 16 0,000 0,09826889 0,1349471 ! tissue regeneration GO:0042246 27 16 0,000 0,09826889 0,13487129 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,09826889 0,13479556 ! biomineral formation GO:0031214 22 16 0,000 0,09826889 0,13471991 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,09826889 0,13464436 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,09826889 0,13456888 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,09826889 0,13449349 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,09826889 0,13441819 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,09826889 0,13434297 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,09826889 0,13426783 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,09826889 0,13419278 ! peptide hormone processing GO:0016486 27 16 0,000 0,09826889 0,13411781 ! regulation of adenylate cyclase activity GO:0045761 165 83 1,000 0,1002713 0,13677431 ! response to drug GO:0042493 149 83 1,000 0,1002713 0,13669798 ! response to nutrient GO:0007584 135 84 1,000 0,10229846 0,1393838 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,1040811 0,14173363 ! metencephalon development GO:0022037 32 17 0,000 0,1040811 0,14165467 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,1040811 0,1415758 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,1040811 0,14149701 ! signal complex assembly GO:0007172 47 17 0,000 0,1040811 0,14141832 ! filopodium assembly GO:0046847 42 17 0,000 0,1040811 0,14133971 ! gene silencing by RNA GO:0031047 38 17 0,000 0,1040811 0,14126119 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,1040811 0,14118275 ! glial cell development GO:0021782 28 17 0,000 0,1040811 0,1411044 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,1040811 0,14102614 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,1040811 0,14094797 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,1040811 0,14086988 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,1040811 0,14079188 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,1040811 0,14071396 ! myoblast differentiation GO:0045445 50 17 0,000 0,1040811 0,14063614 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,1040811 0,14055839 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,1040811 0,14048074 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,1040811 0,14040317 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,1040811 0,14032568 ! NAD metabolic process GO:0019674 33 17 0,000 0,1040811 0,14024828 ! membrane budding GO:0006900 42 17 0,000 0,1040811 0,14017097 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,1040811 0,14009374 ! regulation of protein binding GO:0043393 33 17 0,000 0,1040811 0,14001659 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,1040811 0,13993953 ! genitalia development GO:0048806 32 17 0,000 0,1040811 0,13986256 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,1040811 0,13978567 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,1040811 0,13970886 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,1040811 0,13963214 ! steroid catabolic process GO:0006706 34 17 0,000 0,1040811 0,13955551 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,1040811 0,13947895 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,1040811 0,13940249 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,1040811 0,1393261 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,1040811 0,1392498 ! regulation of cyclase activity GO:0031279 168 85 1,000 0,10433692 0,13951565 ! regulation of transmission of nerve impulse GO:0051969 167 85 1,000 0,10433692 0,13943933 ! regulation of cAMP biosynthetic process GO:0030817 173 86 1,000 0,10638644 0,14210064 ! regulation of lyase activity GO:0051339 169 86 1,000 0,10638644 0,14202299 ! nucleosome assembly GO:0006334 126 87 1,000 0,1084468 0,14469444 ! regulation of protein transport GO:0051223 165 87 1,000 0,1084468 0,14461546 GO:0070201|regulation of establishment of protein localization, ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,10985602 0,14641476 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,10985602 0,14633492 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,10985602 0,14625518 ! limbic system development GO:0021761 40 18 0,000 0,10985602 0,14617552 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,10985602 0,14609595 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,10985602 0,14601646 ! adult walking behavior GO:0007628 36 18 0,000 0,10985602 0,14593706 ! patterning of blood vessels GO:0001569 43 18 0,000 0,10985602 0,14585775 ! heart looping GO:0001947 34 18 0,000 0,10985602 0,14577852 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,10985602 0,14569938 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,10985602 0,14562032 ! glycine metabolic process GO:0006544 30 18 0,000 0,10985602 0,14554135 ! glutamine metabolic process GO:0006541 29 18 0,000 0,10985602 0,14546247 ! response to retinoic acid GO:0032526 31 18 0,000 0,10985602 0,14538367 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,10985602 0,14530496 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,10985602 0,14522633 ! DNA integration GO:0015074 32 18 0,000 0,10985602 0,14514778 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,10985602 0,14506933 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,10985602 0,14499095 ! neural crest cell migration GO:0001755 41 18 0,000 0,10985602 0,14491266 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,10985602 0,14483446 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,10985602 0,14475634 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,10985602 0,1446783 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,10985602 0,14460035 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,10985602 0,14452248 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,10985602 0,1444447 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,10985602 0,144367 ! detection of bacterium GO:0016045 22 18 0,000 0,10985602 0,14428938 ! defense response to virus GO:0051607 43 18 0,000 0,10985602 0,14421185 ! microspike assembly GO:0030035 46 18 0,000 0,10985602 0,1441344 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,10985602 0,14405703 ! chromatin assembly GO:0031497 128 88 1,000 0,11051776 0,14484705 ! regulation of cAMP metabolic process GO:0030814 182 89 1,000 0,11259913 0,1474958 ! regulation of neurological system process GO:0031644 175 89 1,000 0,11259913 0,14741676 ! response to unfolded protein GO:0006986 139 90 1,000 0,11469066 0,15007461 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,11559387 0,1511755 ! positive regulation of translation GO:0045727 31 19 0,000 0,11559387 0,15109461 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,11559387 0,15101381 ! neuron maturation GO:0042551 46 19 0,000 0,11559387 0,1509331 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,11559387 0,15085247 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,11559387 0,15077193 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,11559387 0,15069148 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,11559387 0,15061111 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,11559387 0,15053082 ! memory GO:0007613 34 19 0,000 0,11559387 0,15045063 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,11559387 0,15037052 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,11559387 0,15029049 GO:0042744|hydrogen peroxide catabolic process, ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,11559387 0,15021055 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,11559387 0,15013069 ! cerebral cortex development GO:0021987 40 19 0,000 0,11559387 0,15005092 ! pigmentation during development GO:0048066 42 19 0,000 0,11559387 0,14997123 ! response to vitamin A GO:0033189 32 19 0,000 0,11559387 0,14989163 ! heme metabolic process GO:0042168 40 19 0,000 0,11559387 0,14981211 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,11559387 0,14973268 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,11559387 0,14965333 ! response to fungus GO:0009620 26 19 0,000 0,11559387 0,14957406 ! peptide cross-linking GO:0018149 39 19 0,000 0,11559387 0,14949488 ! protein export from nucleus GO:0006611 40 19 0,000 0,11559387 0,14941578 ! heart process GO:0003015 32 19 0,000 0,11559387 0,14933677 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,11559387 0,14925784 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,11559387 0,14917899 ! visual learning GO:0008542 38 19 0,000 0,11559387 0,14910023 ! cellular pigmentation GO:0033059 37 19 0,000 0,11559387 0,14902154 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,11559387 0,14894295 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,11559387 0,14886443 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,11559387 0,148786 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,11559387 0,14870765 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,11559387 0,14862938 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,11559387 0,1485512 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,11559387 0,1484731 ! cilium assembly GO:0042384 38 19 0,000 0,11559387 0,14839507 ! peptide hormone secretion GO:0030072 32 19 0,000 0,11559387 0,14831714 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 1,000 0,11679216 0,14977598 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! protein-DNA complex assembly GO:0065004 134 92 1,000 0,1189034 0,15240346 ! regulation of cell morphogenesis GO:0022604 243 93 1,000 0,12102417 0,1550404 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 1,000 0,12102417 0,15495915 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 1,000 0,12102417 0,15487797 ! vitamin metabolic process GO:0006766 153 93 1,000 0,12102417 0,15479688 ! protein secretion GO:0009306 45 20 0,000 0,1212949 0,15506198 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,1212949 0,15498088 ! positive regulation of ossification GO:0045778 50 20 0,000 0,1212949 0,15489986 ! skin development GO:0043588 42 20 0,000 0,1212949 0,15481893 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,1212949 0,15473809 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,1212949 0,15465733 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,1212949 0,15457665 ! response to vitamin GO:0033273 36 20 0,000 0,1212949 0,15449606 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,1212949 0,15441555 ! forelimb morphogenesis GO:0035136 35 20 0,000 0,1212949 0,15433512 ! bile acid metabolic process GO:0008206 34 20 0,000 0,1212949 0,15425478 ! response to alkaloid GO:0043279 38 20 0,000 0,1212949 0,15417453 ! retinoid metabolic process GO:0001523 34 20 0,000 0,1212949 0,15409435 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,1212949 0,15401426 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,1212949 0,15393425 ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,1212949 0,15385433 GO:0030968|endoplasmic reticulum unfolded protein response, ! actin filament bundle formation GO:0051017 47 20 0,000 0,1212949 0,15377449 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,1212949 0,15369473 ! peptide secretion GO:0002790 38 20 0,000 0,1212949 0,15361505 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,1212949 0,15353546 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,1212949 0,15345595 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,1212949 0,15337652 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,1212949 0,15329717 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,1212949 0,15321791 ! cell-cell junction organization GO:0045216 43 20 0,000 0,1212949 0,15313873 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,1212949 0,15305963 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,1212949 0,15298061 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,1212949 0,15290167 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,1212949 0,15282281 ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,1212949 0,15274404 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,1212949 0,15266535 ! nitrogen compound catabolic process GO:0044270 167 94 1,000 0,12315427 0,15492579 ! carbohydrate biosynthetic process GO:0016051 158 94 1,000 0,12315427 0,15484605 ! regulation of membrane potential GO:0042391 179 94 1,000 0,12315427 0,1547664 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 1,000 0,12529348 0,15737377 ! regulation of cell killing GO:0031341 46 21 0,000 0,12695934 0,1593842 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,12695934 0,15930234 ! hormone secretion GO:0046879 39 21 0,000 0,12695934 0,15922056 ! cAMP metabolic process GO:0046058 41 21 0,000 0,12695934 0,15913887 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,12695934 0,15905726 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,12695934 0,15897573 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,12695934 0,15889429 ! ovarian follicle development GO:0001541 39 21 0,000 0,12695934 0,15881293 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,12695934 0,15873166 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,12695934 0,15865046 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,12695934 0,15856935 ! sensory perception of pain GO:0019233 33 21 0,000 0,12695934 0,15848833 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,12695934 0,15840738 ! diencephalon development GO:0021536 36 21 0,000 0,12695934 0,15832652 ! collagen fibril organization GO:0030199 62 21 0,000 0,12695934 0,15824574 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,12695934 0,15816505 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,12695934 0,15808443 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,12695934 0,1580039 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,12695934 0,15792345 ! collagen catabolic process GO:0030574 29 21 0,000 0,12695934 0,15784308 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,12695934 0,1577628 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,12695934 0,15768259 ! sperm-egg recognition GO:0035036 23 21 0,000 0,12695934 0,15760247 ! sex differentiation GO:0007548 171 96 1,000 0,12744161 0,1581208 ! response to protein stimulus GO:0051789 158 96 1,000 0,12744161 0,15804054 ! biogenic amine metabolic process GO:0006576 162 97 1,000 0,12959845 0,1606337 ! regulation of protein localization GO:0032880 188 97 1,000 0,12959845 0,16055224 ! forebrain development GO:0030900 210 98 1,000 0,1317638 0,16315204 ! regulation of nucleotide metabolic process GO:0006140 197 98 1,000 0,1317638 0,16306939 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,13258742 0,1640056 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,13258742 0,1639226 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,13258742 0,16383969 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,13258742 0,16375685 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,13258742 0,16367411 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,13258742 0,16359144 ! vacuolar transport GO:0007034 41 22 0,000 0,13258742 0,16350886 ! central nervous system neuron development GO:0021954 47 22 0,000 0,13258742 0,16342637 ! fucose metabolic process GO:0006004 44 22 0,000 0,13258742 0,16334395 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,13258742 0,16326162 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,13258742 0,16317937 ! ureteric bud development GO:0001657 50 22 0,000 0,13258742 0,16309721 ! stem cell differentiation GO:0048863 57 22 0,000 0,13258742 0,16301513 ! cytolysis GO:0019835 27 22 0,000 0,13258742 0,16293313 ! renal system process GO:0003014 42 22 0,000 0,13258742 0,16285121 ! vasodilation GO:0042311 40 22 0,000 0,13258742 0,16276938 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,13258742 0,16268762 ! G1 phase GO:0051318 44 22 0,000 0,13258742 0,16260595 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,13258742 0,16252436 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,13258742 0,16244286 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,13258742 0,16236143 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,13258742 0,16228009 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,13258742 0,16219883 ! sarcomere organization GO:0045214 32 22 0,000 0,13258742 0,16211765 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,13258742 0,16203655 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,13258742 0,16195553 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,13258742 0,16187459 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,13258742 0,16179374 ! gut development GO:0048565 44 22 0,000 0,13258742 0,16171296 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,13258742 0,16163226 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,13258742 0,16155165 ! protein stabilization GO:0050821 41 22 0,000 0,13258742 0,16147112 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,13817937 0,16819741 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,13817937 0,16811365 ! gluconeogenesis GO:0006094 38 23 0,000 0,13817937 0,16802997 ! glycerol metabolic process GO:0006071 40 23 0,000 0,13817937 0,16794637 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,13817937 0,16786286 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,13817937 0,16777943 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,13817937 0,16769608 ! regeneration GO:0031099 42 23 0,000 0,13817937 0,16761281 ! axis specification GO:0009798 43 23 0,000 0,13817937 0,16752963 ! visual behavior GO:0007632 46 23 0,000 0,13817937 0,16744653 ! regulation of DNA recombination GO:0000018 51 23 0,000 0,13817937 0,16736351 ! response to ethanol GO:0045471 47 23 0,000 0,13817937 0,16728058 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,13817937 0,16719773 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,13817937 0,16711495 ! peroxisome organization GO:0007031 43 23 0,000 0,13817937 0,16703227 ! lysosome organization GO:0007040 47 23 0,000 0,13817937 0,16694966 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,13817937 0,16686713 ! vesicle targeting GO:0006903 49 23 0,000 0,13817937 0,16678469 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,13817937 0,16670233 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,13817937 0,16662004 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,13817937 0,16653784 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,13817937 0,16645572 ! fatty acid transport GO:0015908 47 23 0,000 0,13817937 0,16637369 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,13817937 0,16629173 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,13817937 0,16620985 ! hormone transport GO:0009914 41 23 0,000 0,13817937 0,16612806 ! cell-cell recognition GO:0009988 28 23 0,000 0,13817937 0,16604634 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,13817937 0,1659647 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,13817937 0,16588315 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,13817937 0,16580167 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,14373544 0,17238374 GO:0016444|somatic cell DNA recombination, ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,14373544 0,17229915 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,14373544 0,17221465 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,14373544 0,17213023 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,14373544 0,17204589 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,14373544 0,17196164 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,14373544 0,17187747 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,14373544 0,17179338 ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,14373544 0,17170937 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,14373544 0,17162545 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,14373544 0,17154161 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,14373544 0,17145785 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,14373544 0,17137417 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,14373544 0,17129057 ! membrane depolarization GO:0051899 45 24 0,000 0,14373544 0,17120706 ! pallium development GO:0021543 56 24 0,000 0,14373544 0,17112362 ! oogenesis GO:0048477 44 24 0,000 0,14373544 0,17104027 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,14373544 0,170957 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,14373544 0,17087381 ! platelet activation GO:0030168 41 24 0,000 0,14373544 0,1707907 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,14373544 0,17070767 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,14373544 0,17062472 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,14373544 0,17054185 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,14373544 0,17045906 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,14373544 0,17037636 ! regulation of amine transport GO:0051952 41 24 0,000 0,14373544 0,17029373 ! leukocyte adhesion GO:0007159 55 25 0,000 0,14925584 0,17674843 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,14925584 0,17666279 ! phototransduction GO:0007602 37 25 0,000 0,14925584 0,17657724 ! keratinization GO:0031424 37 25 0,000 0,14925584 0,17649177 ! vacuole organization GO:0007033 49 25 0,000 0,14925584 0,17640639 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,14925584 0,17632109 ! receptor metabolic process GO:0043112 53 25 0,000 0,14925584 0,17623587 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,14925584 0,17615073 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,14925584 0,17606567 ! immunoglobulin production GO:0002377 62 25 0,000 0,14925584 0,1759807 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,14925584 0,17589581 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,14925584 0,175811 ! liver development GO:0001889 55 25 0,000 0,14925584 0,17572627 ! initiation of viral infection GO:0019059 60 26 0,000 0,1547408 0,18209623 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,1547408 0,18200856 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,1547408 0,18192097 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,1547408 0,18183346 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,1547408 0,18174604 ! spinal cord development GO:0021510 54 26 0,000 0,1547408 0,18165871 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,1547408 0,18157146 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,1547408 0,18148429 ! digestive system process GO:0022600 49 26 0,000 0,1547408 0,1813972 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,1547408 0,1813102 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,1547408 0,18122328 ! osteoblast differentiation GO:0001649 63 26 0,000 0,1547408 0,18113645 ! neural crest cell development GO:0014032 59 26 0,000 0,1547408 0,1810497 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,1547408 0,18096303 ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,1547408 0,18087645 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,1547408 0,18078994 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,1547408 0,18070352 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,1547408 0,18061719 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,1547408 0,18053093 ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,1547408 0,18044476 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,1547408 0,18035867 ! blastocyst development GO:0001824 50 26 0,000 0,1547408 0,18027266 ! telomere organization GO:0032200 46 26 0,000 0,1547408 0,18018674 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,1547408 0,18010089 ! neural tube closure GO:0001843 58 26 0,000 0,1547408 0,18001513 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,1547408 0,17992945 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,1547408 0,17984385 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,1547408 0,17975833 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,16019055 0,18600072 ! embryonic pattern specification GO:0009880 49 27 0,000 0,16019055 0,18591236 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,16019055 0,18582408 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,16019055 0,18573589 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,16019055 0,18564778 ! iron ion transport GO:0006826 65 27 0,000 0,16019055 0,18555975 ! superoxide metabolic process GO:0006801 41 27 0,000 0,16019055 0,18547181 ! tube lumen formation GO:0035148 59 27 0,000 0,16019055 0,18538395 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,16019055 0,18529617 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,16019055 0,18520848 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,16019055 0,18512087 ! response to toxin GO:0009636 49 27 0,000 0,16019055 0,18503334 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,16019055 0,1849459 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,16019055 0,18485854 ! leukocyte proliferation GO:0070661 59 27 0,000 0,16019055 0,18477126 GO:0032943|mononuclear cell proliferation, ! neuron fate commitment GO:0048663 52 28 0,000 0,16560532 0,19092676 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,16560532 0,1908367 ! vesicle docking GO:0048278 55 28 0,000 0,16560532 0,19074672 ! circadian rhythm GO:0007623 56 28 0,000 0,16560532 0,19065683 ! fat cell differentiation GO:0045444 57 28 0,000 0,16560532 0,19056703 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,16560532 0,19047731 ! sperm motility GO:0030317 37 28 0,000 0,16560532 0,19038767 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,16560532 0,19029812 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,16560532 0,19020865 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,16560532 0,19011927 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,16560532 0,19002997 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,16560532 0,18994075 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,16560532 0,18985162 ! glutathione metabolic process GO:0006749 42 28 0,000 0,16560532 0,18976257 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,16560532 0,18967361 ! lipid oxidation GO:0034440 48 28 0,000 0,16560532 0,18958472 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,16560532 0,18949593 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,17098533 0,19556047 ! translational initiation GO:0006413 66 29 0,000 0,17098533 0,19546896 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,17098533 0,19537753 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,17098533 0,19528619 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,17098533 0,19519494 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,17098533 0,19510377 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,17098533 0,19501268 ! primary neural tube formation GO:0014020 61 29 0,000 0,17098533 0,19492168 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,17098533 0,19483077 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,17098533 0,19473994 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,17098533 0,19464919 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,17098533 0,19455853 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,17098533 0,19446795 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,17098533 0,19437746 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,17098533 0,19428705 ! phenol metabolic process GO:0018958 56 30 0,000 0,1763308 0,20026785 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,1763308 0,20017479 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,1763308 0,20008181 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,1763308 0,19998893 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,1763308 0,19989612 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,1763308 0,19980341 ! acute-phase response GO:0006953 50 30 0,000 0,1763308 0,19971078 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,1763308 0,19961823 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,1763308 0,19952577 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,1763308 0,1994334 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,1763308 0,19934111 ! cell fate determination GO:0001709 64 30 0,000 0,1763308 0,19924891 ! phospholipid transport GO:0015914 65 30 0,000 0,1763308 0,19915679 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,1763308 0,19906476 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,1763308 0,19897282 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,1763308 0,19888095 ! tissue homeostasis GO:0001894 50 30 0,000 0,1763308 0,19878918 GO:0048871|multicellular organismal homeostasis, ! alkaloid metabolic process GO:0009820 57 31 0,000 0,18164195 0,20468233 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,18164195 0,20458796 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,18164195 0,20449368 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,18164195 0,20439949 ! cell junction assembly GO:0034329 85 31 0,000 0,18164195 0,20430538 ! regulation of innate immune response GO:0045088 57 31 0,000 0,18164195 0,20421136 ! ovulation cycle process GO:0022602 55 31 0,000 0,18164195 0,20411743 ! peptide transport GO:0015833 60 31 0,000 0,18164195 0,20402358 ! iron ion homeostasis GO:0055072 60 31 0,000 0,18164195 0,20392982 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,18164195 0,20383615 ! detection of light stimulus GO:0009583 44 31 0,000 0,18164195 0,20374256 ! natural killer cell activation GO:0030101 50 31 0,000 0,18164195 0,20364905 ! cofactor catabolic process GO:0051187 54 31 0,000 0,18164195 0,20355564 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,18164195 0,20346231 ! eye morphogenesis GO:0048592 65 31 0,000 0,18164195 0,20336906 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,18164195 0,2032759 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,18691901 0,20908568 ! collagen metabolic process GO:0032963 49 32 0,000 0,18691901 0,20898999 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,18691901 0,20889439 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,18691901 0,20879887 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,18691901 0,20870344 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,18691901 0,2086081 ! ovulation cycle GO:0042698 57 32 0,000 0,18691901 0,20851285 ! BMP signaling pathway GO:0030509 71 32 0,000 0,18691901 0,20841768 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,18691901 0,2083226 ! gene silencing GO:0016458 71 32 0,000 0,18691901 0,2082276 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,19216218 0,21397092 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,19216218 0,21387344 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,19216218 0,21377605 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,19216218 0,21367874 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,19216218 0,21358153 ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,19216218 0,2134844 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,19216218 0,21338736 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,19216218 0,21329041 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,19216218 0,21319355 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,19737169 0,21887382 ! post-embryonic development GO:0009791 76 34 0,000 0,19737169 0,21877452 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,19737169 0,2186753 ! cholesterol transport GO:0030301 62 34 0,000 0,19737169 0,21857617 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,19737169 0,21847713 ! spliceosome assembly GO:0000245 75 34 0,000 0,19737169 0,21837818 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,19737169 0,21827933 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,19737169 0,21818056 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,19737169 0,21808188 ! adult locomotory behavior GO:0008344 62 34 0,000 0,19737169 0,21798329 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,20254775 0,2235988 ! negative regulation of secretion GO:0051048 68 35 0,000 0,20254775 0,22349781 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,20254775 0,22339691 ! membrane docking GO:0022406 69 35 0,000 0,20254775 0,22329609 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,20254775 0,22319537 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,20254775 0,22309475 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,20254775 0,22299421 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,20254775 0,22289376 ! ceramide metabolic process GO:0006672 72 35 0,000 0,20254775 0,2227934 ! telencephalon development GO:0021537 81 35 0,000 0,20254775 0,22269313 ! sterol transport GO:0015918 63 35 0,000 0,20254775 0,22259296 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,20254775 0,22249287 ! vesicle localization GO:0051648 70 35 0,000 0,20254775 0,22239287 ! regulation of muscle development GO:0048634 82 36 0,000 0,20769057 0,22793714 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,20769057 0,22783479 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,20769057 0,22773253 ! positive regulation of cell development GO:0010720 85 36 0,000 0,20769057 0,22763036 ! protein targeting to membrane GO:0006612 75 36 0,000 0,20769057 0,22752828 ! aerobic respiration GO:0009060 56 36 0,000 0,20769057 0,2274263 ! cytokine production GO:0001816 68 36 0,000 0,20769057 0,2273244 ! embryonic organ development GO:0048568 67 36 0,000 0,20769057 0,2272226 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,20769057 0,22712089 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,20769057 0,22701927 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,21280037 0,23250059 ! odontogenesis GO:0042476 74 37 0,000 0,21280037 0,23239665 ! cell junction organization GO:0034330 96 37 0,000 0,21280037 0,23229281 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,21280037 0,23218906 ! female gonad development GO:0008585 71 37 0,000 0,21280037 0,23208541 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,21280037 0,23198184 ! organic anion transport GO:0015711 82 38 0,000 0,21787736 0,23741053 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,21787736 0,23730468 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,21787736 0,23719893 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,21787736 0,23709327 ! spermatid development GO:0007286 69 38 0,000 0,21787736 0,23698771 ! pigment metabolic process GO:0042440 87 38 0,000 0,21787736 0,23688224 ! neural tube formation GO:0001841 79 38 0,000 0,21787736 0,23677687 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,22292175 0,24215111 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,22292175 0,24204349 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,22292175 0,24193596 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,22292175 0,24182853 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,22292175 0,24172119 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,22292175 0,24161395 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,22793375 0,24693665 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,22793375 0,24682719 ! learning GO:0007612 82 40 0,000 0,22793375 0,24671783 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,22793375 0,24660857 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 75 40 0,000 0,22793375 0,2464994 ! mismatch repair GO:0006298 58 40 0,000 0,22793375 0,24639033 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,22793375 0,24628136 ! RNA export from nucleus GO:0006405 61 41 0,000 0,23291356 0,25155076 ! mRNA catabolic process GO:0006402 79 41 0,000 0,23291356 0,25143961 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,23291356 0,25132855 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,23291356 0,25121758 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,23291356 0,25110672 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,23291356 0,25099595 ! feeding behavior GO:0007631 69 41 0,000 0,23291356 0,25088529 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,23291356 0,25077471 ! mesenchymal cell development GO:0014031 94 41 0,000 0,23291356 0,25066424 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,23291356 0,25055386 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,23291356 0,25044359 ! spermatid differentiation GO:0048515 73 41 0,000 0,23291356 0,2503334 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,23291356 0,25022332 ! RNA modification GO:0009451 64 41 0,000 0,23291356 0,25011333 ! ear morphogenesis GO:0042471 64 42 0,000 0,23786139 0,25531431 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,23786139 0,25520218 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,23786139 0,25509016 ! regulation of protein secretion GO:0050708 77 42 0,000 0,23786139 0,25497822 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,23786139 0,25486639 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,24277744 0,26001986 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,24277744 0,25990591 ! regulation of tube size GO:0035150 76 43 0,000 0,24277744 0,25979207 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,24277744 0,25967832 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,24277744 0,25956468 ! ion transmembrane transport GO:0034220 79 43 0,000 0,24277744 0,25945113 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,24766192 0,26455535 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,24766192 0,26443972 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,24766192 0,26432419 ! phagocytosis GO:0006909 105 44 0,000 0,24766192 0,26420877 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,24766192 0,26409344 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,25251503 0,26915106 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,25251503 0,26903368 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,25251503 0,2689164 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,25251503 0,26879923 ! biopolymer methylation GO:0043414 91 45 0,000 0,25251503 0,26868216 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,25251503 0,26856519 ! female gamete generation GO:0007292 71 45 0,000 0,25251503 0,26844832 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,25251503 0,26833155 ! maintenance of location in cell GO:0051651 101 45 0,000 0,25251503 0,26821488 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,25733698 0,27321783 ! glycolysis GO:0006096 71 46 0,000 0,25733698 0,27309914 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,25733698 0,27298056 ! pigmentation GO:0043473 103 46 0,000 0,25733698 0,27286208 ! neural tube development GO:0021915 91 47 0,000 0,26212794 0,2778215 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,26212794 0,27770103 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,26688814 0,28262147 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,26688814 0,28249902 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,26688814 0,28237667 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,26688814 0,28225443 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,26688814 0,28213229 ! methylation GO:0032259 97 48 0,000 0,26688814 0,28201026 ! response to calcium ion GO:0051592 94 49 0,000 0,27161776 0,28688378 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,27161776 0,28675981 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,27161776 0,28663594 ! JNK cascade GO:0007254 106 49 0,000 0,27161776 0,28651217 ! protein homooligomerization GO:0051260 84 49 0,000 0,27161776 0,28638852 ! regulation of ion transport GO:0043269 86 50 0,000 0,276317 0,29121762 ! endocrine system development GO:0035270 109 50 0,000 0,276317 0,29109204 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,276317 0,29096657 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,276317 0,2908412 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,276317 0,29071595 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,276317 0,2905908 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,276317 0,29046576 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,276317 0,29034083 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,28098606 0,29511992 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,28098606 0,2949931 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,28098606 0,29486638 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,28562512 0,29960591 ! Notch signaling pathway GO:0007219 111 52 0,000 0,28562512 0,29947732 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,28562512 0,29934885 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,28562512 0,29922048 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,28562512 0,29909223 ! excretion GO:0007588 87 52 0,000 0,28562512 0,29896408 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,28562512 0,29883604 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,28562512 0,29870812 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,28562512 0,2985803 ! amino acid activation GO:0043038 98 52 0,000 0,28562512 0,29845259 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,29023438 0,3031392 ! inner ear development GO:0048839 89 53 0,000 0,29023438 0,30300965 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,29023438 0,30288021 ! vesicle organization GO:0016050 127 53 0,000 0,29023438 0,30275089 ! regulation of translational initiation GO:0006446 87 54 0,000 0,29481403 0,30739678 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,29481403 0,30726564 ! neuromuscular process GO:0050905 107 54 0,000 0,29481403 0,30713461 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,29481403 0,30700369 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,29481403 0,30687289 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,29481403 0,30674219 ! RNA catabolic process GO:0006401 103 55 0,000 0,29936425 0,31134392 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,29936425 0,31121144 ! cell maturation GO:0048469 107 55 0,000 0,29936425 0,31107906 ! glucose catabolic process GO:0006007 88 56 0,000 0,30388525 0,31564271 ! RNA elongation GO:0006354 90 56 0,000 0,30388525 0,31550857 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,31284029 0,32466815 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,31284029 0,32453028 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,31284029 0,32439254 ! nuclear export GO:0051168 110 59 0,000 0,3172747 0,32885112 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,32168062 0,3332764 ! regulation of endocytosis GO:0030100 104 60 0,000 0,32168062 0,33313512 ! adult behavior GO:0030534 104 60 0,000 0,32168062 0,33299396 ! positive regulation of secretion GO:0051047 110 61 0,000 0,32605823 0,33738257 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,32605823 0,33723974 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,32605823 0,33709702 ! proton transport GO:0015992 117 61 0,000 0,32605823 0,33695442 ! tRNA processing GO:0008033 102 62 0,000 0,33040771 0,34130488 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,33040771 0,34116063 ! hydrogen transport GO:0006818 121 64 0,000 0,33902301 0,34990841 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,33902301 0,34976065 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,34328918 0,35401244 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,34328918 0,35386306 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,34328918 0,35371382 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,34328918 0,3535647 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,34328918 0,3534157 ! ear development GO:0043583 114 66 0,000 0,34752793 0,35762879 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,34752793 0,35747821 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,35173945 0,36165803 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,35173945 0,36150588 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,35173945 0,36135386 ! secondary metabolic process GO:0019748 125 67 0,000 0,35173945 0,36120196 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,3559239 0,36534541 ! hexose catabolic process GO:0019320 113 68 0,000 0,3559239 0,36519197 ! detection of external stimulus GO:0009581 102 68 0,000 0,3559239 0,36503866 ! adaptive immune response GO:0002250 126 68 0,000 0,3559239 0,36488547 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,36008145 0,36899286 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,36008145 0,36883815 ! single fertilization GO:0007338 83 69 0,000 0,36008145 0,36868356 ! cell redox homeostasis GO:0045454 114 70 0,000 0,36421229 0,37275686 ! activation of immune response GO:0002253 120 70 0,000 0,36421229 0,37260076 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,36421229 0,37244479 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,36831657 0,37648426 ! appendage morphogenesis GO:0035107 150 72 0,000 0,37239447 0,38049339 GO:0035108|limb morphogenesis, ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,37239447 0,38033432 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,37239447 0,38017539 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,37239447 0,38001658 ! appendage development GO:0048736 151 73 0,000 0,37644617 0,38399081 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,37644617 0,38383055 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,37644617 0,38367042 ! regulation of immune effector process GO:0002697 156 73 0,000 0,37644617 0,38351042 ! acute inflammatory response GO:0002526 118 74 0,000 0,38047182 0,38745004 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,38447159 0,39136004 ! rhythmic process GO:0048511 142 75 0,000 0,38447159 0,39119704 ! learning or memory GO:0007611 161 76 0,000 0,38844565 0,39507607 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,38844565 0,39491166 ! regulation of blood pressure GO:0008217 134 76 0,000 0,38844565 0,39474739 ! amine catabolic process GO:0009310 136 77 0,000 0,39239417 0,39859416 ! neurotransmitter transport GO:0006836 142 77 0,000 0,39239417 0,39842849 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,39239417 0,39826296 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,39239417 0,39809757 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,39239417 0,39793232 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,3963173 0,40174405 ! antigen processing and presentation GO:0019882 117 78 0,000 0,3963173 0,40157742 ! fertilization GO:0009566 99 78 0,000 0,3963173 0,40141093 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,40021521 0,40519095 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,40021521 0,4050231 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,40408806 0,40877314 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,40408806 0,40860395 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,40793602 0,41232424 ! exocytosis GO:0006887 153 83 0,000 0,41555787 0,41985437 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,41555787 0,41968081 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,41555787 0,41950738 ! response to metal ion GO:0010038 158 84 0,000 0,41933208 0,42314261 ! digestion GO:0007586 130 84 0,000 0,41933208 0,4229679 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,42308202 0,42657423 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,43050972 0,43388418 ! alcohol catabolic process GO:0046164 142 87 0,000 0,43050972 0,43370526 ! cellular respiration GO:0045333 143 88 0,000 0,43418779 0,43723033 ! amine biosynthetic process GO:0009309 146 88 0,000 0,43418779 0,43705017 ! sensory perception of smell GO:0007608 117 88 0,000 0,43418779 0,43687017 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,43418779 0,43669031 ! tube morphogenesis GO:0035239 194 89 0,000 0,43784221 0,44018457 ! cellular defense response GO:0006968 123 89 0,000 0,43784221 0,4400035 ! response to inorganic substance GO:0010035 173 90 0,000 0,44147312 0,44346992 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,44147312 0,44328764 ! defense response to bacterium GO:0042742 112 91 0,000 0,44508069 0,44672643 ! female pregnancy GO:0007565 166 94 0,000 0,45576478 0,45726216 ! sterol metabolic process GO:0016125 166 94 0,000 0,45576478 0,45707445 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,45928043 0,4604112 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,45928043 0,46022235 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,45928043 0,46003366 ! transcription initiation GO:0006352 171 97 0,000 0,46624404 0,46681729 ! mRNA transport GO:0051028 185 100 0,000 0,47652239 0,47691283 ! positive regulation of immune response GO:0050778 175 100 0,000 0,47652239 0,47671753 ! hormone metabolic process GO:0042445 171 100 0,000 0,47652239 0,47652239