pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6331-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! ER overload response GO:0006983 6 6 2,000 1,238E-05 0,02281858 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 2,000 1,238E-05 0,01140929 ! oxygen transport GO:0015671 7 7 2,000 2,153E-05 0,01322817 ! regulation of cell migration GO:0030334 71 71 5,000 3,145E-05 0,01449223 ! negative regulation of blood coagulation GO:0030195 9 8 2,000 3,424E-05 0,0126202 ! Wnt receptor signaling pathway GO:0016055 46 45 4,000 3,982E-05 0,01223225 ! gas transport GO:0015669 9 9 2,000 5,104E-05 0,01343771 ! regulation of locomotion GO:0040012 79 79 5,000 5,784E-05 0,01332459 ! regulation of cell motion GO:0051270 79 79 5,000 5,784E-05 0,01184408 ! negative regulation of coagulation GO:0050819 11 10 2,000 7,246E-05 0,01335433 ! protein amino acid autophosphorylation GO:0046777 28 28 3,000 9,153E-05 0,01533478 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 2,000 9,901E-05 0,01520691 ! G1/S transition checkpoint GO:0031575 12 11 2,000 9,901E-05 0,01403715 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 2,000 1,695E-04 0,02231383 ! response to endoplasmic reticulum stress GO:0034976 13 13 2,000 1,695E-04 0,02082624 ! protein tetramerization GO:0051262 13 13 2,000 1,695E-04 0,0195246 ! regulation of angiogenesis GO:0045765 35 34 3,000 1,994E-04 0,02161372 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 2,000 2,144E-04 0,02195154 ! regulation of blood coagulation GO:0030193 15 14 2,000 2,144E-04 0,0207962 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 3,000 2,236E-04 0,02060771 ! positive regulation of cell migration GO:0030335 36 36 3,000 2,5E-04 0,02193654 ! insulin receptor signaling pathway GO:0008286 17 15 2,000 2,663E-04 0,02231135 ! ER-nuclear signaling pathway GO:0006984 15 15 2,000 2,663E-04 0,02134129 ! chromosome condensation GO:0030261 15 15 2,000 2,663E-04 0,02045207 ! chromosome segregation GO:0007059 38 38 3,000 3,092E-04 0,0227925 ! regulation of coagulation GO:0050818 17 16 2,000 3,258E-04 0,02309158 ! positive regulation of cell motion GO:0051272 39 39 3,000 3,423E-04 0,02336369 ! positive regulation of glucose metabolic process GO:0010907 5 5 1,000 7,354E-04 0,04840788 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 1,000 7,354E-04 0,04673864 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 1,000 7,354E-04 0,04518068 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! muscle cell migration GO:0014812 5 5 1,000 7,354E-04 0,04372324 ! regulation of phospholipase A2 activity GO:0032429 5 5 1,000 7,354E-04 0,04235689 ! protein heterooligomerization GO:0051291 5 5 1,000 7,354E-04 0,04107335 ! negative regulation of focal adhesion formation GO:0051895 6 5 1,000 7,354E-04 0,03986531 ! T cell lineage commitment GO:0002360 5 5 1,000 7,354E-04 0,0387263 ! peptidyl-lysine modification GO:0018205 5 5 1,000 7,354E-04 0,03765057 ! negative regulation of neuroblast proliferation GO:0007406 5 5 1,000 7,354E-04 0,03663299 ! quaternary ammonium group transport GO:0015697 5 5 1,000 7,354E-04 0,03566896 ! positive regulation of viral reproduction GO:0048524 5 5 1,000 7,354E-04 0,03475437 ! mitotic sister chromatid segregation GO:0000070 21 21 2,000 7,5E-04 0,03455829 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 2,000 7,5E-04 0,0337154 ! mammary gland development GO:0030879 23 21 2,000 7,5E-04 0,03291266 ! cellular response to insulin stimulus GO:0032869 23 21 2,000 7,5E-04 0,03214724 ! cell cycle arrest GO:0007050 49 49 3,000 8,263E-04 0,03460886 ! positive regulation of MAP kinase activity GO:0043406 50 49 3,000 8,263E-04 0,03383978 ! sister chromatid segregation GO:0000819 22 22 2,000 8,631E-04 0,03458043 ! heart development GO:0007507 90 87 4,000 9,106E-04 0,03570747 ! positive regulation of transferase activity GO:0051347 91 88 4,000 9,591E-04 0,03682434 GO:0033674|positive regulation of kinase activity, ! mitotic cell cycle checkpoint GO:0007093 24 23 2,000 9,864E-04 0,03710203 ! calcium-mediated signaling GO:0019722 23 23 2,000 9,864E-04 0,03635999 ! cell projection assembly GO:0030031 25 23 2,000 9,864E-04 0,03564705 ! regulation of body fluid levels GO:0050878 55 52 3,000 1,035E-03 0,03669706 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 1,000 1,097E-03 0,03814569 ! N-terminal protein amino acid modification GO:0031365 6 6 1,000 1,097E-03 0,03743929 GO:0018409|peptide or protein amino-terminal blocking, ! virus-host interaction GO:0019048 6 6 1,000 1,097E-03 0,03675857 ! regulation of lipid kinase activity GO:0043550 6 6 1,000 1,097E-03 0,03610217 ! arginine metabolic process GO:0006525 6 6 1,000 1,097E-03 0,0354688 GO:0006527|arginine catabolic process, ! oligodendrocyte differentiation GO:0048709 6 6 1,000 1,097E-03 0,03485727 ! negative regulation of T cell proliferation GO:0042130 6 6 1,000 1,097E-03 0,03426647 GO:0070667|negative regulation of mast cell proliferation, ! asymmetric protein localization GO:0008105 6 6 1,000 1,097E-03 0,03369536 ! peptidyl-serine phosphorylation GO:0018105 6 6 1,000 1,097E-03 0,03314298 ! G1 DNA damage checkpoint GO:0031571 6 6 1,000 1,097E-03 0,03260841 ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 1,097E-03 0,03209082 ! regulation of focal adhesion formation GO:0051893 7 6 1,000 1,097E-03 0,0315894 ! ribosomal large subunit biogenesis GO:0042273 6 6 1,000 1,097E-03 0,03110341 ! nitric oxide mediated signal transduction GO:0007263 6 6 1,000 1,097E-03 0,03063214 ! organic cation transport GO:0015695 6 6 1,000 1,097E-03 0,03017495 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 1,000 1,097E-03 0,0297312 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! regulation of embryonic development GO:0045995 6 6 1,000 1,097E-03 0,02930031 ! localization within membrane GO:0051668 6 6 1,000 1,097E-03 0,02888174 ! negative regulation of cell cycle GO:0045786 92 91 4,000 1,116E-03 0,02896949 ! regulation of gene-specific transcription GO:0032583 25 25 2,000 1,265E-03 0,03238833 ! regulation of T cell proliferation GO:0042129 25 25 2,000 1,265E-03 0,03194466 ! extracellular structure organization GO:0043062 56 56 3,000 1,369E-03 0,03408956 ! negative regulation of cell migration GO:0030336 26 26 2,000 1,422E-03 0,03493137 ! regulation of T cell differentiation GO:0045580 26 26 2,000 1,422E-03 0,03447175 ! response to insulin stimulus GO:0032868 28 26 2,000 1,422E-03 0,03402406 ! synapse organization GO:0050808 26 26 2,000 1,422E-03 0,03358786 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 1,000 1,527E-03 0,03562704 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 1,000 1,527E-03 0,0351817 ! positive regulation of cellular catabolic process GO:0031331 7 7 1,000 1,527E-03 0,03474736 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 1,000 1,527E-03 0,03432361 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! cardiac muscle tissue development GO:0048738 7 7 1,000 1,527E-03 0,03391008 ! response to X-ray GO:0010165 7 7 1,000 1,527E-03 0,03350638 ! regulation of intracellular pH GO:0051453 7 7 1,000 1,527E-03 0,03311219 ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 1,000 1,527E-03 0,03272717 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! axon cargo transport GO:0008088 7 7 1,000 1,527E-03 0,03235099 ! cranial nerve development GO:0021545 7 7 1,000 1,527E-03 0,03198337 ! induction of an organ GO:0001759 7 7 1,000 1,527E-03 0,031624 ! autonomic nervous system development GO:0048483 7 7 1,000 1,527E-03 0,03127263 ! response to gamma radiation GO:0010332 8 7 1,000 1,527E-03 0,03092897 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 1,000 1,527E-03 0,03059279 GO:0001953|negative regulation of cell-matrix adhesion, ! negative regulation of T cell activation GO:0050868 7 7 1,000 1,527E-03 0,03026383 ! posttranscriptional regulation of gene expression GO:0010608 98 98 4,000 1,556E-03 0,03050231 ! peptidyl-amino acid modification GO:0018193 61 59 3,000 1,663E-03 0,03227087 ! regulation of mast cell proliferation GO:0070666 28 28 2,000 1,769E-03 0,03396249 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 3,000 1,771E-03 0,03364442 ! positive regulation of cell cycle GO:0045787 29 29 2,000 1,961E-03 0,03687926 ! regulation of epithelial cell proliferation GO:0050678 29 29 2,000 1,961E-03 0,03650674 ! regulation of lymphocyte proliferation GO:0050670 29 29 2,000 1,961E-03 0,03614168 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! response to UV GO:0009411 29 29 2,000 1,961E-03 0,03578384 ! negative regulation of proteolysis GO:0045861 8 8 1,000 2,025E-03 0,03658511 ! sex determination GO:0007530 8 8 1,000 2,025E-03 0,03622992 ! negative regulation of mitotic cell cycle GO:0045930 9 8 1,000 2,025E-03 0,03588155 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 1,000 2,025E-03 0,03553982 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 1,000 2,025E-03 0,03520454 ! peptidyl-serine modification GO:0018209 8 8 1,000 2,025E-03 0,03487553 ! cofactor transport GO:0051181 8 8 1,000 2,025E-03 0,03455261 ! regulation of RNA stability GO:0043487 8 8 1,000 2,025E-03 0,03423561 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 1,000 2,025E-03 0,03392438 ! release of cytochrome c from mitochondria GO:0001836 9 8 1,000 2,025E-03 0,03361875 ! developmental induction GO:0031128 8 8 1,000 2,025E-03 0,03331858 GO:0045168|cell-cell signaling involved in cell fate specification, ! negative regulation of cellular component organization GO:0051129 65 63 3,000 2,121E-03 0,03460019 ! regulation of response to external stimulus GO:0032101 65 64 3,000 2,248E-03 0,03634713 ! regulation of DNA replication GO:0006275 32 31 2,000 2,383E-03 0,03818564 ! negative regulation of cell motion GO:0051271 31 31 2,000 2,383E-03 0,03785645 ! regulation of MAP kinase activity GO:0043405 67 66 3,000 2,517E-03 0,03965565 ! negative regulation of protein metabolic process GO:0051248 66 66 3,000 2,517E-03 0,03931959 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 1,000 2,589E-03 0,04009244 ! cortical actin cytoskeleton organization GO:0030866 10 9 1,000 2,589E-03 0,03975834 ! negative regulation of cell cycle process GO:0010948 9 9 1,000 2,589E-03 0,03942976 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 1,000 2,589E-03 0,03910656 ! copper ion transport GO:0006825 9 9 1,000 2,589E-03 0,03878862 ! RNA polyadenylation GO:0043631 9 9 1,000 2,589E-03 0,03847581 GO:0006378|mRNA polyadenylation, ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 1,000 2,589E-03 0,03816801 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 1,000 2,589E-03 0,03786508 ! regulation of cellular pH GO:0030641 9 9 1,000 2,589E-03 0,03756693 ! histone acetylation GO:0016573 9 9 1,000 2,589E-03 0,03727344 ! negative regulation of inflammatory response GO:0050728 9 9 1,000 2,589E-03 0,0369845 ! negative regulation of cell growth GO:0030308 32 32 2,000 2,613E-03 0,03704436 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 2,000 2,613E-03 0,03676158 ! regulation of lymphocyte differentiation GO:0045619 32 32 2,000 2,613E-03 0,03648308 ! striated muscle tissue development GO:0014706 69 67 3,000 2,66E-03 0,03686078 ! negative regulation of cell size GO:0045792 33 33 2,000 2,857E-03 0,03928889 ! regulation of mitotic cell cycle GO:0007346 72 69 3,000 2,962E-03 0,04043249 ! response to peptide hormone stimulus GO:0043434 36 34 2,000 3,114E-03 0,04219589 ! wound healing GO:0042060 74 70 3,000 3,121E-03 0,04198463 ! muscle tissue development GO:0060537 72 70 3,000 3,121E-03 0,04168039 ! regulation of glucose metabolic process GO:0010906 10 10 1,000 3,218E-03 0,0426645 ! cortical cytoskeleton organization GO:0030865 11 10 1,000 3,218E-03 0,04235975 ! inositol metabolic process GO:0006020 10 10 1,000 3,218E-03 0,04205933 ! apoptotic mitochondrial changes GO:0008637 11 10 1,000 3,218E-03 0,04176313 ! purine ribonucleoside metabolic process GO:0046128 10 10 1,000 3,218E-03 0,04147108 GO:0042278|purine nucleoside metabolic process, ! neuromuscular junction development GO:0007528 10 10 1,000 3,218E-03 0,04118309 ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 1,000 3,218E-03 0,04089907 ! intermediate filament cytoskeleton organization GO:0045104 10 10 1,000 3,218E-03 0,04061894 ! nerve development GO:0021675 10 10 1,000 3,218E-03 0,04034262 ! positive regulation of neuron apoptosis GO:0043525 10 10 1,000 3,218E-03 0,04007003 ! mRNA 3'-end processing GO:0031124 10 10 1,000 3,218E-03 0,03980111 ! mesoderm development GO:0007498 35 35 2,000 3,385E-03 0,04158666 ! positive regulation of phosphorylation GO:0042327 35 35 2,000 3,385E-03 0,04131125 ! positive regulation of phosphorus metabolic process GO:0010562 36 36 2,000 3,67E-03 0,04449481 GO:0045937|positive regulation of phosphate metabolic process, ! integrin-mediated signaling pathway GO:0007229 36 36 2,000 3,67E-03 0,044204 ! coagulation GO:0050817 39 36 2,000 3,67E-03 0,04391696 GO:0007596|blood coagulation, ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 1,000 3,911E-03 0,04650111 ! negative regulation of defense response GO:0031348 11 11 1,000 3,911E-03 0,04620303 ! microtubule-based transport GO:0010970 11 11 1,000 3,911E-03 0,04590874 ! endothelial cell migration GO:0043542 11 11 1,000 3,911E-03 0,04561818 ! protein amino acid acetylation GO:0006473 11 11 1,000 3,911E-03 0,04533127 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 1,000 3,911E-03 0,04504795 GO:0032388|positive regulation of intracellular transport, ! regulation of transmembrane transporter activity GO:0022898 11 11 1,000 3,911E-03 0,04476815 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! regulation of viral genome replication GO:0045069 11 11 1,000 3,911E-03 0,0444918 ! cellular response to starvation GO:0009267 11 11 1,000 3,911E-03 0,04421885 ! cellular macromolecular complex disassembly GO:0034623 12 11 1,000 3,911E-03 0,04394922 ! apoptotic nuclear changes GO:0030262 11 11 1,000 3,911E-03 0,04368286 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 1,000 3,911E-03 0,04341971 ! body fluid secretion GO:0007589 11 11 1,000 3,911E-03 0,04315971 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 1,000 3,911E-03 0,04290281 ! intermediate filament-based process GO:0045103 11 11 1,000 3,911E-03 0,04264895 ! interaction with host GO:0051701 11 11 1,000 3,911E-03 0,04239807 ! regulation of monooxygenase activity GO:0032768 11 11 1,000 3,911E-03 0,04215013 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 1,000 3,911E-03 0,04190507 GO:0006109|regulation of carbohydrate metabolic process, ! vitamin transport GO:0051180 11 11 1,000 3,911E-03 0,04166284 ! hindbrain development GO:0030902 11 11 1,000 3,911E-03 0,0414234 ! RNA 3'-end processing GO:0031123 11 11 1,000 3,911E-03 0,0411867 ! negative regulation of lymphocyte activation GO:0051250 11 11 1,000 3,911E-03 0,04095268 ! lung development GO:0030324 38 37 2,000 3,969E-03 0,04132591 ! negative regulation of growth GO:0045926 37 37 2,000 3,969E-03 0,04109374 ! microtubule-based movement GO:0007018 82 78 3,000 4,611E-03 0,04747301 ! hemostasis GO:0007599 42 39 2,000 4,611E-03 0,04721103 ! respiratory tube development GO:0030323 40 39 2,000 4,611E-03 0,04695019 ! respiratory system development GO:0060541 40 39 2,000 4,611E-03 0,04669223 ! protein oligomerization GO:0051259 39 39 2,000 4,611E-03 0,04643708 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 1,000 4,667E-03 0,04674373 ! positive regulation of angiogenesis GO:0045766 12 12 1,000 4,667E-03 0,04649106 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 1,000 4,667E-03 0,04624111 ! heterophilic cell adhesion GO:0007157 12 12 1,000 4,667E-03 0,04599383 ! mitotic chromosome condensation GO:0007076 12 12 1,000 4,667E-03 0,04574918 ! barbed-end actin filament capping GO:0051016 12 12 1,000 4,667E-03 0,04550712 GO:0051693|actin filament capping, ! regulation of alpha-beta T cell activation GO:0046634 12 12 1,000 4,667E-03 0,04526761 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 1,000 4,667E-03 0,04503061 ! regulation of chromosome organization GO:0033044 12 12 1,000 4,667E-03 0,04479607 ! somitogenesis GO:0001756 13 12 1,000 4,667E-03 0,04456397 ! synaptogenesis GO:0007416 12 12 1,000 4,667E-03 0,04433426 ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 1,000 4,667E-03 0,0441069 ! negative regulation of translation GO:0017148 12 12 1,000 4,667E-03 0,04388187 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 1,000 4,667E-03 0,04365912 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 1,000 4,667E-03 0,04343862 ! cell cycle checkpoint GO:0000075 42 41 2,000 5,312E-03 0,04920028 ! positive regulation of DNA replication GO:0045740 14 13 1,000 5,484E-03 0,05053919 ! negative regulation of actin filament polymerization GO:0030837 13 13 1,000 5,484E-03 0,05028775 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 1,000 5,484E-03 0,0500388 ! mitochondrial membrane organization GO:0007006 13 13 1,000 5,484E-03 0,0497923 ! negative regulation of DNA replication GO:0008156 13 13 1,000 5,484E-03 0,04954822 ! negative regulation of protein catabolic process GO:0042177 13 13 1,000 5,484E-03 0,04930652 ! cell aging GO:0007569 13 13 1,000 5,484E-03 0,04906717 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 1,000 5,484E-03 0,04883013 ! negative regulation of protein kinase cascade GO:0010741 13 13 1,000 5,484E-03 0,04859537 ! regulation of viral reproduction GO:0050792 13 13 1,000 5,484E-03 0,04836286 ! negative regulation of phosphorylation GO:0042326 13 13 1,000 5,484E-03 0,04813256 ! negative regulation of leukocyte activation GO:0002695 13 13 1,000 5,484E-03 0,04790444 ! regulation of cell-substrate adhesion GO:0010810 14 13 1,000 5,484E-03 0,04767848 GO:0001952|regulation of cell-matrix adhesion, ! blood vessel morphogenesis GO:0048514 84 83 3,000 5,751E-03 0,04976448 ! protein amino acid acylation GO:0043543 14 14 1,000 6,363E-03 0,0547973 ! macromolecular complex disassembly GO:0032984 15 14 1,000 6,363E-03 0,05454243 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 1,000 6,363E-03 0,05428992 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 1,000 6,363E-03 0,05403973 GO:0045936|negative regulation of phosphate metabolic process, ! base-excision repair GO:0006284 14 14 1,000 6,363E-03 0,05379185 ! DNA modification GO:0006304 14 14 1,000 6,363E-03 0,05354622 ! negative regulation of protein polymerization GO:0032272 14 14 1,000 6,363E-03 0,05330283 ! negative regulation of organelle organization GO:0010639 45 44 2,000 6,479E-03 0,0540339 ! positive regulation of protein kinase activity GO:0045860 89 86 3,000 6,519E-03 0,05411979 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 3,000 6,519E-03 0,0538771 ! homophilic cell adhesion GO:0007156 45 45 2,000 6,9E-03 0,05676766 ! phosphoinositide-mediated signaling GO:0048015 45 45 2,000 6,9E-03 0,05651536 ! protein import into nucleus, translocation GO:0000060 15 15 1,000 7,301E-03 0,0595363 ! negative regulation of actin filament depolymerization GO:0030835 15 15 1,000 7,301E-03 0,05927402 ! negative regulation of protein complex assembly GO:0031333 15 15 1,000 7,301E-03 0,05901405 ! response to starvation GO:0042594 15 15 1,000 7,301E-03 0,05875634 ! response to ionizing radiation GO:0010212 16 15 1,000 7,301E-03 0,05850088 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 1,000 7,301E-03 0,05824763 ! negative regulation of cell activation GO:0050866 15 15 1,000 7,301E-03 0,05799656 ! cellular response to hormone stimulus GO:0032870 48 46 2,000 7,336E-03 0,05802438 ! regulation of catabolic process GO:0009894 48 47 2,000 7,788E-03 0,0613373 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 1,000 8,297E-03 0,06507066 ! regulation of synaptic plasticity GO:0048167 16 16 1,000 8,297E-03 0,06479494 ! positive regulation of mitosis GO:0045840 16 16 1,000 8,297E-03 0,06452154 GO:0051785|positive regulation of nuclear division, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 1,000 8,297E-03 0,06425045 ! segmentation GO:0035282 17 16 1,000 8,297E-03 0,06398162 ! triglyceride metabolic process GO:0006641 16 16 1,000 8,297E-03 0,06371503 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 1,000 8,297E-03 0,06345065 ! cell fate specification GO:0001708 16 16 1,000 8,297E-03 0,06318845 ! cellular response to nutrient levels GO:0031669 16 16 1,000 8,297E-03 0,06292842 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 1,000 8,297E-03 0,06267052 ! polyol metabolic process GO:0019751 16 16 1,000 8,297E-03 0,06241472 ! glutamine family amino acid catabolic process GO:0009065 17 16 1,000 8,297E-03 0,062161 ! positive regulation of catabolic process GO:0009896 16 16 1,000 8,297E-03 0,06190934 ! gland development GO:0048732 51 49 2,000 8,741E-03 0,06495558 ! skeletal muscle tissue development GO:0007519 50 49 2,000 8,741E-03 0,06469472 GO:0060538|skeletal muscle organ development, ! regulation of response to stress GO:0080134 97 94 3,000 8,892E-03 0,06554884 ! blood vessel development GO:0001568 95 94 3,000 8,892E-03 0,06528769 ! regulation of DNA metabolic process GO:0051052 51 50 2,000 9,242E-03 0,06758829 ! nitrogen compound catabolic process GO:0044270 51 50 2,000 9,242E-03 0,06732114 ! regulation of neurogenesis GO:0050767 51 50 2,000 9,242E-03 0,0670561 ! anterior/posterior pattern formation GO:0009952 51 50 2,000 9,242E-03 0,06679313 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 9,351E-03 0,06731986 ! myelination GO:0042552 17 17 1,000 9,351E-03 0,06705791 ! regulation of transmembrane transport GO:0034762 17 17 1,000 9,351E-03 0,066798 ! negative regulation of cell development GO:0010721 18 17 1,000 9,351E-03 0,06654009 GO:0050768|negative regulation of neurogenesis, ! regulation of oxidoreductase activity GO:0051341 17 17 1,000 9,351E-03 0,06628417 ! regulation of fibroblast proliferation GO:0048145 17 17 1,000 9,351E-03 0,06603021 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 1,000 9,351E-03 0,06577818 ! regulation of actin filament depolymerization GO:0030834 17 17 1,000 9,351E-03 0,06552808 ! embryonic skeletal system morphogenesis GO:0048704 17 17 1,000 9,351E-03 0,06527986 ! regulation of cell growth GO:0001558 97 96 3,000 9,562E-03 0,06650253 ! vasculature development GO:0001944 97 96 3,000 9,562E-03 0,06625252 ! rRNA metabolic process GO:0016072 51 51 2,000 9,759E-03 0,06736314 GO:0006364|rRNA processing, ! interphase of mitotic cell cycle GO:0051329 52 51 2,000 9,759E-03 0,06711178 GO:0051325|interphase, ! cell fate commitment GO:0045165 52 52 2,000 0,01029317 0,07052159 ! response to light stimulus GO:0009416 53 52 2,000 0,01029317 0,0702604 ! regulation of cellular catabolic process GO:0031329 18 18 1,000 0,01046127 0,07114433 ! meiosis I GO:0007127 18 18 1,000 0,01046127 0,07088277 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 1,000 0,01046127 0,07062313 ! negative regulation of response to external stimulus GO:0032102 18 18 1,000 0,01046127 0,07036538 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 1,000 0,01046127 0,07010951 ! neutral lipid metabolic process GO:0006638 18 18 1,000 0,01046127 0,06985549 GO:0006639|acylglycerol metabolic process, ! B cell differentiation GO:0030183 18 18 1,000 0,01046127 0,0696033 ! cellular response to extracellular stimulus GO:0031668 18 18 1,000 0,01046127 0,06935293 ! ensheathment of neurons GO:0007272 18 18 1,000 0,01046127 0,06910435 GO:0008366|axon ensheathment, ! regulation of microtubule-based process GO:0032886 18 18 1,000 0,01046127 0,06885755 ! negative regulation of catabolic process GO:0009895 18 18 1,000 0,01046127 0,06861251 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 1,000 0,01046127 0,0683692 ! ectoderm development GO:0007398 99 99 3,000 0,01062874 0,06921825 ! sodium ion transport GO:0006814 53 53 2,000 0,010844 0,07037142 ! response to hypoxia GO:0001666 53 53 2,000 0,010844 0,07012451 ! regulation of T cell activation GO:0050863 53 53 2,000 0,010844 0,06987932 ! muscle organ development GO:0007517 102 100 3,000 0,01100069 0,07064204 ! protein amino acid dephosphorylation GO:0006470 55 54 2,000 0,01141165 0,07302661 ! response to oxygen levels GO:0070482 55 54 2,000 0,01141165 0,07277393 ! negative regulation of multicellular organismal process GO:0051241 55 54 2,000 0,01141165 0,07252298 ! DNA damage checkpoint GO:0000077 19 19 1,000 0,01162691 0,07363711 ! negative regulation of DNA metabolic process GO:0051053 19 19 1,000 0,01162691 0,07338493 ! glial cell differentiation GO:0010001 19 19 1,000 0,01162691 0,07313446 ! regulation of pH GO:0006885 19 19 1,000 0,01162691 0,07288571 ! regulation of JAK-STAT cascade GO:0046425 19 19 1,000 0,01162691 0,07263864 ! positive regulation of T cell proliferation GO:0042102 19 19 1,000 0,01162691 0,07239324 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 1,000 0,01162691 0,07214949 ! ribonucleoside metabolic process GO:0009119 19 19 1,000 0,01162691 0,07190738 ! positive regulation of T cell differentiation GO:0045582 19 19 1,000 0,01162691 0,07166688 ! peripheral nervous system development GO:0007422 19 19 1,000 0,01162691 0,07142799 ! regulation of protein stability GO:0031647 19 19 1,000 0,01162691 0,07119069 ! dorsal/ventral pattern formation GO:0009953 19 19 1,000 0,01162691 0,07095496 ! microtubule cytoskeleton organization GO:0000226 55 55 2,000 0,01199621 0,07296703 ! regulation of cell adhesion GO:0030155 56 55 2,000 0,01199621 0,07272701 ! regulation of nervous system development GO:0051960 57 56 2,000 0,01259776 0,07612352 ! negative regulation of cell adhesion GO:0007162 21 20 1,000 0,01284691 0,07737536 ! establishment or maintenance of cell polarity GO:0007163 21 20 1,000 0,01284691 0,07712333 ! organic ether metabolic process GO:0018904 20 20 1,000 0,01284691 0,07687293 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 1,000 0,01284691 0,07662415 ! nucleus organization GO:0006997 20 20 1,000 0,01284691 0,07637697 ! positive regulation of gene-specific transcription GO:0043193 20 20 1,000 0,01284691 0,07613139 ! peptidyl-tyrosine modification GO:0018212 21 20 1,000 0,01284691 0,07588738 ! DNA integrity checkpoint GO:0031570 21 21 1,000 0,01412027 0,08314266 ! regulation of action potential in neuron GO:0019228 21 21 1,000 0,01412027 0,08287788 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 1,000 0,01412027 0,08261477 ! regulation of proteolysis GO:0030162 21 21 1,000 0,01412027 0,08235334 ! negative regulation of hydrolase activity GO:0051346 21 21 1,000 0,01412027 0,08209355 ! dephosphorylation GO:0016311 60 59 2,000 0,01450511 0,08406579 ! regulation of cell development GO:0060284 60 59 2,000 0,01450511 0,08380226 ! protein polymerization GO:0051258 65 60 2,000 0,01517534 0,08740048 ! positive regulation of transcription factor activity GO:0051091 22 22 1,000 0,01544598 0,08868209 GO:0090047|positive regulation of transcription regulator activity, ! positive regulation of DNA metabolic process GO:0051054 23 22 1,000 0,01544598 0,08840668 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 1,000 0,01544598 0,08813297 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! embryonic skeletal system development GO:0048706 22 22 1,000 0,01544598 0,08786096 ! spindle organization GO:0007051 22 22 1,000 0,01544598 0,08759061 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 1,000 0,01544598 0,08732193 ! cytokinesis GO:0000910 23 22 1,000 0,01544598 0,08705489 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 2,000 0,01586289 0,08913201 ! regulation of cellular component biogenesis GO:0044087 63 62 2,000 0,0165678 0,09280988 ! regulation of lymphocyte activation GO:0051249 62 62 2,000 0,0165678 0,09252863 ! negative regulation of protein complex disassembly GO:0043242 23 23 1,000 0,01682308 0,09367053 ! positive regulation of growth GO:0045927 23 23 1,000 0,01682308 0,09338839 ! monovalent inorganic cation homeostasis GO:0055067 23 23 1,000 0,01682308 0,09310794 ! angiogenesis GO:0001525 65 64 2,000 0,01802988 0,09948821 ! glycerolipid metabolic process GO:0046486 65 64 2,000 0,01802988 0,09919123 ! regulation of cytoskeleton organization GO:0051493 66 64 2,000 0,01802988 0,09889602 ! mitochondrial transport GO:0006839 24 24 1,000 0,0182506 0,09980967 ! regulation of action potential GO:0001508 24 24 1,000 0,0182506 0,09951438 ! gliogenesis GO:0042063 24 24 1,000 0,0182506 0,09922083 ! glucose homeostasis GO:0042593 24 24 1,000 0,0182506 0,098929 GO:0033500|carbohydrate homeostasis, ! T cell differentiation GO:0030217 24 24 1,000 0,0182506 0,09863889 ! androgen receptor signaling pathway GO:0030521 24 24 1,000 0,0182506 0,09835047 ! glucan metabolic process GO:0044042 25 24 1,000 0,0182506 0,09806373 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! anion transport GO:0006820 65 65 2,000 0,01878712 0,10065307 ! DNA packaging GO:0006323 66 66 2,000 0,01956186 0,10450003 ! regulation of actin filament polymerization GO:0030833 25 25 1,000 0,01972758 0,10508075 ! cellular component disassembly GO:0022411 26 25 1,000 0,01972758 0,10477792 ! regulation of intracellular protein transport GO:0033157 25 25 1,000 0,01972758 0,10447683 ! positive regulation of DNA binding GO:0043388 26 25 1,000 0,01972758 0,10417747 ! heart morphogenesis GO:0003007 25 25 1,000 0,01972758 0,10387982 ! negative regulation of immune system process GO:0002683 25 25 1,000 0,01972758 0,10358387 ! JAK-STAT cascade GO:0007259 26 25 1,000 0,01972758 0,1032896 ! response to radiation GO:0009314 70 68 2,000 0,02116395 0,11049621 ! regulation of cell size GO:0008361 68 68 2,000 0,02116395 0,11018407 ! positive regulation of binding GO:0051099 27 26 1,000 0,02125309 0,11033647 ! induction of apoptosis by intracellular signals GO:0008629 26 26 1,000 0,02125309 0,11002653 ! double-strand break repair GO:0006302 27 26 1,000 0,02125309 0,10971833 ! regulation of translation GO:0006417 69 69 2,000 0,02199133 0,11321233 ! regionalization GO:0003002 70 69 2,000 0,02199133 0,11289698 ! response to nutrient levels GO:0031667 69 69 2,000 0,02199133 0,11258337 ! regulation of leukocyte activation GO:0002694 69 69 2,000 0,02199133 0,11227151 ! chloride transport GO:0006821 27 27 1,000 0,02282619 0,11621179 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 1,000 0,02282619 0,11589165 ! energy reserve metabolic process GO:0006112 28 27 1,000 0,02282619 0,11557327 ! peptide metabolic process GO:0006518 29 27 1,000 0,02282619 0,11525663 ! activation of caspase activity GO:0006919 27 27 1,000 0,02282619 0,11494172 ! glutamine family amino acid metabolic process GO:0009064 28 27 1,000 0,02282619 0,11462853 ! ribosome biogenesis GO:0042254 71 71 2,000 0,02369878 0,11868711 ! negative regulation of signal transduction GO:0009968 71 71 2,000 0,02369878 0,11836546 ! regulation of cell activation GO:0050865 71 71 2,000 0,02369878 0,11804556 ! histone modification GO:0016570 28 28 1,000 0,02444597 0,12143914 ! positive regulation of hydrolase activity GO:0051345 72 72 2,000 0,02457887 0,12177111 ! response to extracellular stimulus GO:0009991 72 72 2,000 0,02457887 0,12144464 ! viral reproductive process GO:0022415 29 29 1,000 0,02611152 0,12867255 ! phosphoinositide metabolic process GO:0030384 29 29 1,000 0,02611152 0,12832942 ! covalent chromatin modification GO:0016569 29 29 1,000 0,02611152 0,12798812 ! regulation of protein polymerization GO:0032271 29 29 1,000 0,02611152 0,12764863 ! positive regulation of protein transport GO:0051222 29 29 1,000 0,02611152 0,12731093 ! transition metal ion transport GO:0000041 31 30 1,000 0,02782195 0,1352925 ! positive regulation of peptidase activity GO:0010952 30 30 1,000 0,02782195 0,13493647 GO:0043280|positive regulation of caspase activity, ! activation of phospholipase C activity GO:0007202 30 30 1,000 0,02782195 0,1345823 GO:0010863|positive regulation of phospholipase C activity, ! regulation of protein complex disassembly GO:0043244 30 30 1,000 0,02782195 0,13422999 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 1,000 0,02782195 0,13387952 ! skeletal system morphogenesis GO:0048705 31 30 1,000 0,02782195 0,13353088 ! regulation of inflammatory response GO:0050727 30 30 1,000 0,02782195 0,13318405 ! water-soluble vitamin metabolic process GO:0006767 30 30 1,000 0,02782195 0,13283901 ! establishment of organelle localization GO:0051656 31 30 1,000 0,02782195 0,13249576 ! negative regulation of cell communication GO:0010648 76 76 2,000 0,02827476 0,13430511 ! skeletal muscle fiber development GO:0048741 31 31 1,000 0,02957638 0,14012666 ! B cell activation GO:0042113 31 31 1,000 0,02957638 0,13976736 ! negative regulation of cytoskeleton organization GO:0051494 32 31 1,000 0,02957638 0,1394099 ! positive regulation of phospholipase activity GO:0010518 31 31 1,000 0,02957638 0,13905427 ! aging GO:0007568 32 31 1,000 0,02957638 0,13870044 ! nucleoside metabolic process GO:0009116 31 31 1,000 0,02957638 0,13834841 ! extracellular matrix organization GO:0030198 31 31 1,000 0,02957638 0,13799816 ! regulation of intracellular transport GO:0032386 31 31 1,000 0,02957638 0,13764968 ! regulation of myeloid cell differentiation GO:0045637 32 31 1,000 0,02957638 0,13730295 ! regulation of protein modification process GO:0031399 79 78 2,000 0,03022782 0,13997455 ! positive regulation of protein kinase cascade GO:0010740 79 78 2,000 0,03022782 0,13962373 ! muscle fiber development GO:0048747 32 32 1,000 0,03137394 0,14455543 ! lipid modification GO:0030258 32 32 1,000 0,03137394 0,14419494 ! regulation of phospholipase activity GO:0010517 32 32 1,000 0,03137394 0,14383625 ! positive regulation of lipase activity GO:0060193 32 32 1,000 0,03137394 0,14347934 ! neuron projection development GO:0031175 85 80 2,000 0,03225069 0,14712382 ! amino acid transport GO:0006865 33 33 1,000 0,03321377 0,15114315 ! regulation of protein complex assembly GO:0043254 33 33 1,000 0,03321377 0,15077088 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 1,000 0,03321377 0,15040043 ! regulation of neuron differentiation GO:0045664 34 33 1,000 0,03321377 0,1500318 ! regulation of neuron apoptosis GO:0043523 34 33 1,000 0,03321377 0,14966498 ! regulation of synaptic transmission GO:0050804 33 33 1,000 0,03321377 0,14929994 ! tube development GO:0035295 83 81 2,000 0,03328823 0,14927056 ! regulation of actin filament length GO:0030832 34 34 1,000 0,03509502 0,15699059 ! cellular polysaccharide metabolic process GO:0044264 35 34 1,000 0,03509502 0,15661047 ! regulation of protein catabolic process GO:0042176 35 34 1,000 0,03509502 0,15623218 ! regulation of lipid metabolic process GO:0019216 34 34 1,000 0,03509502 0,15585572 ! negative regulation of response to stimulus GO:0048585 34 34 1,000 0,03509502 0,15548106 ! viral reproduction GO:0016032 34 34 1,000 0,03509502 0,15510821 ! ncRNA processing GO:0034470 83 83 2,000 0,0354153 0,15614927 ! regulation of cellular component size GO:0032535 35 35 1,000 0,03701686 0,16282117 ! inorganic anion transport GO:0015698 35 35 1,000 0,03701686 0,1624335 ! positive regulation of cell differentiation GO:0045597 87 85 2,000 0,03761141 0,16465042 ! regulation of mitosis GO:0007088 37 36 1,000 0,03897846 0,17023056 GO:0051783|regulation of nuclear division, ! positive regulation of organelle organization GO:0010638 36 36 1,000 0,03897846 0,16982812 ! heterocycle catabolic process GO:0046700 36 36 1,000 0,03897846 0,16942759 ! regulation of transmission of nerve impulse GO:0051969 36 36 1,000 0,03897846 0,16902893 ! regulation of lipase activity GO:0060191 36 36 1,000 0,03897846 0,16863215 ! regulation of transcription factor activity GO:0051090 38 37 1,000 0,040979 0,1768719 GO:0090046|regulation of transcription regulator activity, ! meiosis GO:0007126 37 37 1,000 0,040979 0,17645865 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of protein kinase activity GO:0006469 37 37 1,000 0,040979 0,17604733 ! response to drug GO:0042493 37 37 1,000 0,040979 0,17563791 ! DNA damage response, signal transduction GO:0042770 37 37 1,000 0,040979 0,1752304 ! cellular amino acid catabolic process GO:0009063 38 37 1,000 0,040979 0,17482477 ! chemotaxis GO:0006935 90 89 2,000 0,04220908 0,17965667 GO:0042330|taxis, ! rRNA transcription GO:0009303 5 5 0,000 0,04286295 0,18201941 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,04286295 0,18160097 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,04286295 0,18118446 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,04286295 0,18076985 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,04286295 0,18035713 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,04286295 0,17994629 ! reproductive cellular process GO:0048610 5 5 0,000 0,04286295 0,17953733 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,04286295 0,17913021 ! prostate gland development GO:0030850 5 5 0,000 0,04286295 0,17872494 ! metencephalon development GO:0022037 5 5 0,000 0,04286295 0,1783215 ! water transport GO:0006833 5 5 0,000 0,04286295 0,17791987 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,04286295 0,17752005 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,04286295 0,17712202 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,04286295 0,17672578 ! glycerol metabolic process GO:0006071 5 5 0,000 0,04286295 0,1763313 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,04286295 0,17593858 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,04286295 0,17554761 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,04286295 0,17515837 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,04286295 0,17477085 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,04286295 0,17438504 ! filopodium assembly GO:0046847 7 5 0,000 0,04286295 0,17400093 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,04286295 0,17361851 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,04286295 0,17323777 ! GTP metabolic process GO:0046039 5 5 0,000 0,04286295 0,17285869 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,04286295 0,17248127 ! mRNA stabilization GO:0048255 5 5 0,000 0,04286295 0,1721055 GO:0043489|RNA stabilization, ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,04286295 0,17173135 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,04286295 0,17135884 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,04286295 0,17098793 ! social behavior GO:0035176 5 5 0,000 0,04286295 0,17061862 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,04286295 0,17025091 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,04286295 0,16988478 ! memory GO:0007613 5 5 0,000 0,04286295 0,16952022 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 0,04286295 0,16915722 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,04286295 0,16879578 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,04286295 0,16843587 ! response to lipid GO:0033993 5 5 0,000 0,04286295 0,1680775 ! erythrocyte maturation GO:0043249 5 5 0,000 0,04286295 0,16772064 ! hippocampus development GO:0021766 6 5 0,000 0,04286295 0,1673653 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,04286295 0,16701147 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,04286295 0,16665912 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,04286295 0,16630826 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,04286295 0,16595887 ! mechanosensory behavior GO:0007638 5 5 0,000 0,04286295 0,16561095 ! heart looping GO:0001947 5 5 0,000 0,04286295 0,16526448 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,04286295 0,16491946 ! response to interferon-gamma GO:0034341 5 5 0,000 0,04286295 0,16457588 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,04286295 0,16423373 ! endocrine pancreas development GO:0031018 5 5 0,000 0,04286295 0,16389299 ! pH reduction GO:0045851 5 5 0,000 0,04286295 0,16355367 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,04286295 0,16321575 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,04286295 0,16287922 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,04286295 0,16254408 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,04286295 0,16221031 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,04286295 0,16187792 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,04286295 0,16154688 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,04286295 0,16121719 ! adrenal gland development GO:0030325 5 5 0,000 0,04286295 0,16088885 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,04286295 0,16056184 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,04286295 0,16023615 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,04286295 0,15991179 ! astrocyte differentiation GO:0048708 5 5 0,000 0,04286295 0,15958873 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,04286295 0,15926698 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,04286295 0,15894653 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,04286295 0,15862736 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,04286295 0,15830946 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,04286295 0,15799285 ! microtubule nucleation GO:0007020 5 5 0,000 0,04286295 0,15767749 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,04286295 0,15736339 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,04286295 0,15705054 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,04286295 0,15673893 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,04286295 0,15642856 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,04286295 0,15611941 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,04286295 0,15581149 ! response to ATP GO:0033198 5 5 0,000 0,04286295 0,15550477 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,04286295 0,15519926 ! regulation of appetite GO:0032098 5 5 0,000 0,04286295 0,15489495 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,04286295 0,15459183 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,04286295 0,15428989 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,04286295 0,15398913 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,04286295 0,15368954 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,04286295 0,15339111 ! receptor clustering GO:0043113 5 5 0,000 0,04286295 0,15309384 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,04286295 0,15279772 ! fear response GO:0042596 5 5 0,000 0,04286295 0,15250275 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 0,04286295 0,15220891 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,04286295 0,1519162 ! retinol metabolic process GO:0042572 5 5 0,000 0,04286295 0,15162461 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,04286295 0,15133414 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,04286295 0,15104479 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,04286295 0,15075653 ! parturition GO:0007567 5 5 0,000 0,04286295 0,15046938 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,04286295 0,15018331 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,04286295 0,14989834 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,04286295 0,14961444 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,04286295 0,14933161 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,04286295 0,14904985 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,04286295 0,14876916 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,04286295 0,14848952 ! response to UV-B GO:0010224 5 5 0,000 0,04286295 0,14821092 ! oligodendrocyte development GO:0014003 5 5 0,000 0,04286295 0,14793338 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,04286295 0,14765687 ! activated T cell proliferation GO:0050798 5 5 0,000 0,04286295 0,14738139 ! interaction with symbiont GO:0051702 5 5 0,000 0,04286295 0,14710693 ! cellular extravasation GO:0045123 5 5 0,000 0,04286295 0,1468335 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,04286295 0,14656108 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,04286295 0,14628967 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,04286295 0,14601927 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,04286295 0,14574986 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,04286295 0,14548144 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,04286295 0,14521401 ! response to amine stimulus GO:0014075 5 5 0,000 0,04286295 0,14494757 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,04286295 0,14468209 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,04286295 0,14441759 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,04286295 0,14415406 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,04286295 0,14389148 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,04286295 0,14362986 ! neuron recognition GO:0008038 5 5 0,000 0,04286295 0,14336919 ! decidualization GO:0046697 5 5 0,000 0,04286295 0,14310946 ! hair follicle maturation GO:0048820 5 5 0,000 0,04286295 0,14285067 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,04286295 0,14259282 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,04286295 0,1423359 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,04286295 0,1420799 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,04286295 0,14182482 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,04286295 0,14157065 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,04286295 0,14131739 ! postreplication repair GO:0006301 5 5 0,000 0,04286295 0,14106504 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,04286295 0,14081359 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 0,04286295 0,14056303 ! histone methylation GO:0016571 5 5 0,000 0,04286295 0,14031336 ! DNA methylation GO:0006306 5 5 0,000 0,04286295 0,14006458 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,04286295 0,13981668 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,04286295 0,13956965 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,04286295 0,1393235 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,04286295 0,13907821 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,04286295 0,13883378 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,04286295 0,13859022 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,04286295 0,1383475 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,04286295 0,13810563 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,04286295 0,13786461 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,04286295 0,13762443 ! sterol catabolic process GO:0016127 5 5 0,000 0,04286295 0,13738508 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,04286295 0,13714657 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,04286295 0,13690888 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,04286295 0,13667201 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,04286295 0,13643596 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,04286295 0,13620073 ! zymogen activation GO:0031638 5 5 0,000 0,04286295 0,1359663 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,04286295 0,13573269 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,04286295 0,13549987 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,04286295 0,13526785 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,04286295 0,13503662 ! nucleosome positioning GO:0016584 5 5 0,000 0,04286295 0,13480618 ! regulation of isotype switching GO:0045191 5 5 0,000 0,04286295 0,13457653 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,04286295 0,13434766 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,04286295 0,13411956 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,04286295 0,13389224 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,04286295 0,13366569 ! NADPH regeneration GO:0006740 5 5 0,000 0,04286295 0,1334399 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,04286295 0,13321488 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,04286295 0,13299061 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,04286295 0,1327671 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,04286295 0,13254433 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,04286295 0,13232232 ! sarcomere organization GO:0045214 5 5 0,000 0,04286295 0,13210104 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,04286295 0,13188051 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,04286295 0,13166071 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,04286295 0,13144164 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,04286295 0,13122329 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 0,04286295 0,13100568 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,04286295 0,13078878 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,04286295 0,1305726 ! spleen development GO:0048536 5 5 0,000 0,04286295 0,13035713 ! male genitalia development GO:0030539 5 5 0,000 0,04286295 0,13014238 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,04286295 0,12992833 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,04286295 0,12971498 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,04286295 0,12950233 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,04286295 0,12929038 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,04286295 0,12907912 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,04286295 0,12886855 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,04286295 0,12865867 ! ATP catabolic process GO:0006200 5 5 0,000 0,04286295 0,12844947 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,04286295 0,12824095 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,04286295 0,1280331 ! blastocyst formation GO:0001825 5 5 0,000 0,04286295 0,12782593 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,04286295 0,12761942 ! embryonic gut development GO:0048566 5 5 0,000 0,04286295 0,12741359 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,04286295 0,12720841 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,04286295 0,1270039 ! activation of innate immune response GO:0002218 5 5 0,000 0,04286295 0,12680004 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 0,04286295 0,12659683 ! catecholamine transport GO:0051937 5 5 0,000 0,04286295 0,12639428 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,04286295 0,12619237 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,04286295 0,12599111 ! muscle adaptation GO:0043500 5 5 0,000 0,04286295 0,12579048 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,04286295 0,1255905 ! embryonic heart tube development GO:0035050 5 5 0,000 0,04286295 0,12539115 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,04286295 0,12519243 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,04286295 0,12499434 ! defense response to fungus GO:0050832 5 5 0,000 0,04286295 0,12479688 ! lysogeny GO:0030069 5 5 0,000 0,04286295 0,12460004 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,04286295 0,12440382 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,04286295 0,12420821 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,04286295 0,12401322 ! response to nicotine GO:0035094 5 5 0,000 0,04286295 0,12381884 ! establishment of cell polarity GO:0030010 5 5 0,000 0,04286295 0,12362508 ! mitochondrion localization GO:0051646 5 5 0,000 0,04286295 0,12343191 ! nucleus localization GO:0051647 5 5 0,000 0,04286295 0,12323935 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,04286295 0,12304739 ! negative regulation of kinase activity GO:0033673 38 38 1,000 0,04301769 0,12329954 ! cell-matrix adhesion GO:0007160 39 38 1,000 0,04301769 0,12310809 ! meiotic cell cycle GO:0051321 38 38 1,000 0,04301769 0,12291722 ! axon guidance GO:0007411 39 38 1,000 0,04301769 0,12272695 ! regulation of neurological system process GO:0031644 38 38 1,000 0,04301769 0,12253726 ! steroid hormone receptor signaling pathway GO:0030518 38 38 1,000 0,04301769 0,12234816 ! brain development GO:0007420 91 90 2,000 0,04340096 0,12324803 ! DNA replication GO:0006260 91 91 2,000 0,0446097 0,12648565 ! positive regulation of protein modification process GO:0031401 39 39 1,000 0,04509373 0,12766167 ! activation of MAPK activity GO:0000187 39 39 1,000 0,04509373 0,12746587 ! response to unfolded protein GO:0006986 39 39 1,000 0,04509373 0,12727067 ! nucleotide-excision repair GO:0006289 40 39 1,000 0,04509373 0,12707607 ! cytokine-mediated signaling pathway GO:0019221 39 39 1,000 0,04509373 0,12688206 ! positive regulation of T cell activation GO:0050870 39 39 1,000 0,04509373 0,12668864 ! lymphocyte differentiation GO:0030098 39 39 1,000 0,04509373 0,12649581 ! negative regulation of transferase activity GO:0051348 40 40 1,000 0,04720634 0,1322208 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 1,000 0,04720634 0,13202016 ! organelle localization GO:0051640 41 40 1,000 0,04720634 0,13182013 ! pattern specification process GO:0007389 96 94 2,000 0,04833633 0,13477133 ! amine catabolic process GO:0009310 42 41 1,000 0,04935474 0,13740301 ! regulation of caspase activity GO:0043281 41 41 1,000 0,04935474 0,13719577 ! axon extension GO:0048675 7 6 0,000 0,05121615 0,14215567 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,05121615 0,1419419 ! tRNA modification GO:0006400 6 6 0,000 0,05121615 0,14172877 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,05121615 0,14151629 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,05121615 0,14130444 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,05121615 0,14109322 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,05121615 0,14088263 ! regulation of S phase GO:0033261 6 6 0,000 0,05121615 0,14067267 ! myotube differentiation GO:0014902 6 6 0,000 0,05121615 0,14046334 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,05121615 0,14025463 ! bone remodeling GO:0046849 6 6 0,000 0,05121615 0,14004653 ! N-glycan processing GO:0006491 6 6 0,000 0,05121615 0,13983906 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,05121615 0,13963219 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,05121615 0,13942594 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,05121615 0,1392203 ! RNA methylation GO:0001510 6 6 0,000 0,05121615 0,13901526 ! cartilage condensation GO:0001502 7 6 0,000 0,05121615 0,13881083 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,05121615 0,13860699 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 0,05121615 0,13840376 GO:0050927|positive regulation of positive chemotaxis, ! succinate metabolic process GO:0006105 7 6 0,000 0,05121615 0,13820112 ! artery development GO:0060840 6 6 0,000 0,05121615 0,13799907 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,05121615 0,13779761 ! bile acid metabolic process GO:0008206 6 6 0,000 0,05121615 0,13759674 ! androgen metabolic process GO:0008209 6 6 0,000 0,05121615 0,13739645 ! estrogen metabolic process GO:0008210 6 6 0,000 0,05121615 0,13719675 ! limbic system development GO:0021761 7 6 0,000 0,05121615 0,13699762 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,05121615 0,13679908 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 0,000 0,05121615 0,1366011 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,05121615 0,1364037 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,05121615 0,13620687 ! pathogenesis GO:0009405 6 6 0,000 0,05121615 0,13601061 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,05121615 0,13581491 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,05121615 0,13561977 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,05121615 0,1354252 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,05121615 0,13523118 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,05121615 0,13503772 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,05121615 0,1348448 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,05121615 0,13465244 ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,05121615 0,13446063 ! glutamate catabolic process GO:0006538 7 6 0,000 0,05121615 0,13426936 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,05121615 0,13407864 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,05121615 0,13388846 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,05121615 0,13369881 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,05121615 0,13350971 ! V(D)J recombination GO:0033151 6 6 0,000 0,05121615 0,13332113 ! focal adhesion formation GO:0048041 7 6 0,000 0,05121615 0,13313309 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,05121615 0,13294558 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,05121615 0,1327586 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,05121615 0,13257214 ! regulation of heart rate GO:0002027 6 6 0,000 0,05121615 0,1323862 ! lipid digestion GO:0044241 6 6 0,000 0,05121615 0,13220079 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,05121615 0,13201589 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,05121615 0,13183151 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,05121615 0,13164765 ! regulation of vascular permeability GO:0043114 6 6 0,000 0,05121615 0,13146429 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,05121615 0,13128145 ! ruffle organization GO:0031529 6 6 0,000 0,05121615 0,13109912 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,05121615 0,13091729 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,05121615 0,13073596 ! neutral amino acid transport GO:0015804 6 6 0,000 0,05121615 0,13055514 ! L-amino acid transport GO:0015807 6 6 0,000 0,05121615 0,13037481 ! bone mineralization GO:0030282 6 6 0,000 0,05121615 0,13019498 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,05121615 0,13001565 ! negative regulation of ossification GO:0030279 6 6 0,000 0,05121615 0,12983681 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,05121615 0,12965847 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of bone resorption GO:0045124 6 6 0,000 0,05121615 0,12948061 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,05121615 0,12930324 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,05121615 0,12912635 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,05121615 0,12894995 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,05121615 0,12877403 ! regulation of organ growth GO:0046620 6 6 0,000 0,05121615 0,12859859 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,05121615 0,12842362 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,05121615 0,12824913 ! response to dsRNA GO:0043331 6 6 0,000 0,05121615 0,12807512 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,05121615 0,12790158 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,05121615 0,1277285 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! genitalia development GO:0048806 6 6 0,000 0,05121615 0,1275559 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,05121615 0,12738376 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,05121615 0,12721208 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,05121615 0,12704087 ! multicellular organismal aging GO:0010259 6 6 0,000 0,05121615 0,12687011 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,05121615 0,12669982 ! erythrocyte development GO:0048821 6 6 0,000 0,05121615 0,12652998 ! renal water homeostasis GO:0003091 6 6 0,000 0,05121615 0,12636059 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,05121615 0,12619166 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,05121615 0,12602318 ! ribosome assembly GO:0042255 6 6 0,000 0,05121615 0,12585515 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,05121615 0,12568757 ! diencephalon development GO:0021536 6 6 0,000 0,05121615 0,12552043 ! fucose catabolic process GO:0019317 6 6 0,000 0,05121615 0,12535374 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,05121615 0,12518748 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 0,05121615 0,12502167 ! regulation of lipid transport GO:0032368 6 6 0,000 0,05121615 0,1248563 ! regulation of cell division GO:0051302 6 6 0,000 0,05121615 0,12469137 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,05121615 0,12452686 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,05121615 0,1243628 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,05121615 0,12419916 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,05121615 0,12403596 ! neuroblast proliferation GO:0007405 6 6 0,000 0,05121615 0,12387318 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,05121615 0,12371083 ! regulation of glucose transport GO:0010827 6 6 0,000 0,05121615 0,1235489 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,05121615 0,1233874 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,05121615 0,12322632 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,05121615 0,12306566 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,05121615 0,12290542 ! thymus development GO:0048538 6 6 0,000 0,05121615 0,1227456 ! lymph node development GO:0048535 6 6 0,000 0,05121615 0,12258619 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,05121615 0,12242719 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,05121615 0,12226861 ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,05121615 0,12211043 ! sperm-egg recognition GO:0035036 7 6 0,000 0,05121615 0,12195267 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,05121615 0,12179531 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,05121615 0,12163835 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,05121615 0,12148181 ! alditol metabolic process GO:0019400 6 6 0,000 0,05121615 0,12132566 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,05121615 0,12116991 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,05121615 0,12101457 ! maternal placenta development GO:0001893 6 6 0,000 0,05121615 0,12085962 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,05121615 0,12070507 ! regulation of endopeptidase activity GO:0052548 42 42 1,000 0,05153818 0,12130891 ! cell-substrate adhesion GO:0031589 43 42 1,000 0,05153818 0,12115417 ! response to protein stimulus GO:0051789 42 42 1,000 0,05153818 0,12099984 ! forebrain development GO:0030900 43 42 1,000 0,05153818 0,12084589 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 1,000 0,05153818 0,12069234 ! mitochondrion organization GO:0007005 44 43 1,000 0,05375591 0,12572606 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 1,000 0,05600717 0,13082536 ! protein import into nucleus GO:0006606 44 44 1,000 0,05600717 0,13065976 ! vitamin metabolic process GO:0006766 44 44 1,000 0,05600717 0,13049458 ! positive regulation of lymphocyte activation GO:0051251 44 44 1,000 0,05600717 0,13032981 ! response to hormone stimulus GO:0009725 102 100 2,000 0,05623453 0,13069388 ! regulation of actin cytoskeleton organization GO:0032956 46 45 1,000 0,05829124 0,13530322 ! regulation of DNA binding GO:0051101 47 45 1,000 0,05829124 0,13513303 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 1,000 0,05829124 0,13496326 ! nuclear import GO:0051170 45 45 1,000 0,05829124 0,13479393 ! respiratory burst GO:0045730 7 7 0,000 0,05949765 0,13741124 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,05949765 0,13723926 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,05949765 0,13706771 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,05949765 0,13689659 ! regulation of chemokine production GO:0032642 7 7 0,000 0,05949765 0,1367259 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,05949765 0,13655563 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,05949765 0,13638578 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,05949765 0,13621636 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,05949765 0,13604735 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,05949765 0,13587877 ! gene silencing by RNA GO:0031047 7 7 0,000 0,05949765 0,1357106 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,05949765 0,13554285 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,05949765 0,13537552 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,05949765 0,13520859 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,05949765 0,13504208 ! axis specification GO:0009798 7 7 0,000 0,05949765 0,13487598 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,05949765 0,13471028 ! visual behavior GO:0007632 7 7 0,000 0,05949765 0,13454499 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,05949765 0,13438011 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,05949765 0,13421563 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,05949765 0,13405155 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,05949765 0,13388787 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,05949765 0,13372459 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,05949765 0,13356171 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,05949765 0,13339923 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,05949765 0,13323714 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,05949765 0,13307545 ! digestive system development GO:0055123 7 7 0,000 0,05949765 0,13291414 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,05949765 0,13275323 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,05949765 0,13259271 ! protein targeting to ER GO:0045047 8 7 0,000 0,05949765 0,13243257 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,05949765 0,13227282 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,05949765 0,13211346 ! endoderm development GO:0007492 7 7 0,000 0,05949765 0,13195447 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,05949765 0,13179587 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,05949765 0,13163766 GO:0006688|glycosphingolipid biosynthetic process, ! regulation of mRNA processing GO:0050684 7 7 0,000 0,05949765 0,13147982 ! response to hexose stimulus GO:0009746 7 7 0,000 0,05949765 0,13132236 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,05949765 0,13116527 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,05949765 0,13100856 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,05949765 0,13085223 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,05949765 0,13069627 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,05949765 0,13054068 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,05949765 0,13038546 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,05949765 0,1302306 ! UV protection GO:0009650 7 7 0,000 0,05949765 0,13007612 ! DNA integration GO:0015074 7 7 0,000 0,05949765 0,129922 ! myofibril assembly GO:0030239 7 7 0,000 0,05949765 0,12976825 GO:0055002|striated muscle cell development, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,05949765 0,12961486 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,05949765 0,12946183 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,05949765 0,12930916 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,05949765 0,12915685 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,05949765 0,1290049 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,05949765 0,12885331 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,05949765 0,12870207 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,05949765 0,12855119 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,05949765 0,12840066 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,05949765 0,12825049 ! eating behavior GO:0042755 7 7 0,000 0,05949765 0,12810066 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,05949765 0,12795119 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,05949765 0,12780206 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,05949765 0,12765328 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,05949765 0,12750485 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,05949765 0,12735676 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,05949765 0,12720901 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,05949765 0,12706161 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,05949765 0,12691455 ! intracellular lipid transport GO:0032365 7 7 0,000 0,05949765 0,12676782 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,05949765 0,12662144 ! platelet activation GO:0030168 8 7 0,000 0,05949765 0,1264754 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,05949765 0,12632969 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,05949765 0,12618431 ! natural killer cell activation GO:0030101 7 7 0,000 0,05949765 0,12603927 ! NADP metabolic process GO:0006739 7 7 0,000 0,05949765 0,12589457 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,05949765 0,12575019 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,05949765 0,12560615 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,05949765 0,12546243 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,05949765 0,12531905 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,05949765 0,12517599 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,05949765 0,12503326 ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,05949765 0,12489085 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,05949765 0,12474877 ! cell-cell recognition GO:0009988 8 7 0,000 0,05949765 0,12460701 ! hormone catabolic process GO:0042447 7 7 0,000 0,05949765 0,12446557 ! dopamine metabolic process GO:0042417 7 7 0,000 0,05949765 0,12432445 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,05949765 0,12418366 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,05949765 0,12404318 ! regulation of mRNA stability GO:0043488 7 7 0,000 0,05949765 0,12390301 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,05949765 0,12376317 ! regulation of axon extension GO:0030516 7 7 0,000 0,05949765 0,12362364 ! cell killing GO:0001906 7 7 0,000 0,05949765 0,12348442 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,05949765 0,12334552 ! adult feeding behavior GO:0008343 7 7 0,000 0,05949765 0,12320693 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,05949765 0,12306865 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,05949765 0,12293068 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,05949765 0,12279302 ! response to cold GO:0009409 7 7 0,000 0,05949765 0,12265567 ! regulation of actin filament-based process GO:0032970 47 46 1,000 0,0606074 0,12480385 ! regulation of peptidase activity GO:0052547 46 46 1,000 0,0606074 0,12466456 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 1,000 0,0606074 0,12452558 ! positive regulation of ligase activity GO:0051351 47 46 1,000 0,0606074 0,12438691 ! regulation of membrane potential GO:0042391 46 46 1,000 0,0606074 0,12424855 ! amine transport GO:0015837 47 47 1,000 0,06295494 0,12891773 ! actin filament organization GO:0007015 50 48 1,000 0,06533315 0,13363929 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 1,000 0,06533315 0,13349113 ! regulation of cell cycle process GO:0010564 50 48 1,000 0,06533315 0,1333433 ! glycerophospholipid metabolic process GO:0006650 49 48 1,000 0,06533315 0,1331958 ! protein localization in nucleus GO:0034504 48 48 1,000 0,06533315 0,13304862 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,06770806 0,13773284 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,06770806 0,13758098 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,06770806 0,13742946 ! positive regulation of translation GO:0045727 8 8 0,000 0,06770806 0,13727827 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,06770806 0,13712742 ! superoxide anion generation GO:0042554 8 8 0,000 0,06770806 0,1369769 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,06770806 0,1368267 ! cGMP metabolic process GO:0046068 8 8 0,000 0,06770806 0,13667684 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,06770806 0,1365273 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,06770806 0,13637809 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,06770806 0,1362292 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,06770806 0,13608065 ! negative regulation of bone remodeling GO:0046851 8 8 0,000 0,06770806 0,13593241 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,06770806 0,1357845 ! zinc ion transport GO:0006829 8 8 0,000 0,06770806 0,1356369 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,06770806 0,13548963 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,06770806 0,13534268 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,06770806 0,13519605 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,06770806 0,13504973 ! lipid localization GO:0010876 8 8 0,000 0,06770806 0,13490373 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,06770806 0,13475805 ! response to cAMP GO:0051591 8 8 0,000 0,06770806 0,13461268 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,06770806 0,13446762 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,06770806 0,13432288 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,06770806 0,13417844 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,06770806 0,13403432 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,06770806 0,13389051 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,06770806 0,133747 ! sensory perception of taste GO:0050909 8 8 0,000 0,06770806 0,1336038 ! organelle fusion GO:0048284 8 8 0,000 0,06770806 0,13346091 ! pancreas development GO:0031016 8 8 0,000 0,06770806 0,13331832 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,06770806 0,13317604 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,06770806 0,13303406 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,06770806 0,13289239 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,06770806 0,13275101 ! sperm motility GO:0030317 8 8 0,000 0,06770806 0,13260994 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,06770806 0,13246916 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,06770806 0,13232869 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,06770806 0,13218851 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,06770806 0,13204863 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,06770806 0,13190904 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,06770806 0,13176975 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,06770806 0,13163075 ! Golgi organization GO:0007030 8 8 0,000 0,06770806 0,13149205 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,06770806 0,13135363 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,06770806 0,13121551 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 0,06770806 0,13107768 ! fructose metabolic process GO:0006000 8 8 0,000 0,06770806 0,13094014 ! mannose metabolic process GO:0006013 9 8 0,000 0,06770806 0,13080288 ! NAD metabolic process GO:0019674 8 8 0,000 0,06770806 0,13066592 ! plasma membrane fusion GO:0045026 8 8 0,000 0,06770806 0,13052924 ! response to fungus GO:0009620 8 8 0,000 0,06770806 0,13039284 ! stem cell differentiation GO:0048863 8 8 0,000 0,06770806 0,13025673 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,06770806 0,13012091 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,06770806 0,12998537 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,06770806 0,12985011 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,06770806 0,12971513 ! regulation of vasodilation GO:0042312 8 8 0,000 0,06770806 0,12958043 ! vasoconstriction GO:0042310 8 8 0,000 0,06770806 0,12944601 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,06770806 0,12931187 ! muscle cell development GO:0055001 8 8 0,000 0,06770806 0,129178 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,06770806 0,12904442 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,06770806 0,12891111 ! sensory perception of pain GO:0019233 8 8 0,000 0,06770806 0,12877807 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,06770806 0,12864531 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,06770806 0,12851282 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,06770806 0,12838061 ! chromatin silencing GO:0006342 8 8 0,000 0,06770806 0,12824867 ! tissue regeneration GO:0042246 8 8 0,000 0,06770806 0,12811699 ! salivary gland development GO:0007431 8 8 0,000 0,06770806 0,12798559 ! T cell homeostasis GO:0043029 8 8 0,000 0,06770806 0,12785446 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,06770806 0,12772359 ! water homeostasis GO:0030104 8 8 0,000 0,06770806 0,127593 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,06770806 0,12746267 ! acid secretion GO:0046717 8 8 0,000 0,06770806 0,1273326 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 0,06770806 0,1272028 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,06770806 0,12707327 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,06770806 0,126944 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,06770806 0,12681499 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,06770806 0,12668625 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,06770806 0,12655776 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,06770806 0,12642954 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,06770806 0,12630157 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,06770806 0,12617386 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,06770806 0,12604642 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,06770806 0,12591922 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,06770806 0,12579229 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,06770806 0,12566561 ! peptide hormone secretion GO:0030072 8 8 0,000 0,06770806 0,12553919 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,06770806 0,12541302 ! actin filament polymerization GO:0030041 9 8 0,000 0,06770806 0,1252871 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 0,06770806 0,12516144 ! peptide hormone processing GO:0016486 8 8 0,000 0,06770806 0,12503602 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,06770806 0,12491086 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,06770806 0,12478595 ! leukocyte differentiation GO:0002521 50 49 1,000 0,06774134 0,12472258 ! ossification GO:0001503 50 49 1,000 0,06774134 0,1245981 GO:0060348|bone development, ! response to nutrient GO:0007584 49 49 1,000 0,06774134 0,12447388 ! regulation of ligase activity GO:0051340 50 49 1,000 0,06774134 0,1243499 ! positive regulation of cell activation GO:0050867 49 49 1,000 0,06774134 0,12422617 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 1,000 0,07017883 0,12856818 ! T cell activation GO:0042110 51 50 1,000 0,07017883 0,12844051 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 1,000 0,07017883 0,12831309 ! biogenic amine metabolic process GO:0006576 52 51 1,000 0,07264495 0,13269042 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 1,000 0,07513902 0,13711011 ! lactation GO:0007595 10 9 0,000 0,07584798 0,13826688 ! embryonic pattern specification GO:0009880 10 9 0,000 0,07584798 0,13813026 ! positive regulation of cell size GO:0045793 9 9 0,000 0,07584798 0,1379939 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,07584798 0,13785781 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,07584798 0,13772199 ! viral genome replication GO:0019079 9 9 0,000 0,07584798 0,13758644 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,07584798 0,13745115 ! lipid phosphorylation GO:0046834 9 9 0,000 0,07584798 0,13731613 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,07584798 0,13718137 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,07584798 0,13704688 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,07584798 0,13691265 ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,07584798 0,13677869 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,07584798 0,13664499 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,07584798 0,13651154 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,07584798 0,13637836 ! phospholipid efflux GO:0033700 9 9 0,000 0,07584798 0,13624544 ! response to alkaloid GO:0043279 10 9 0,000 0,07584798 0,13611278 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,07584798 0,13598037 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,07584798 0,13584822 GO:0042107|cytokine metabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 9 9 0,000 0,07584798 0,13571633 ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,07584798 0,13558469 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,07584798 0,13545331 ! response to ethanol GO:0045471 9 9 0,000 0,07584798 0,13532219 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,07584798 0,13519132 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,07584798 0,1350607 ! methionine metabolic process GO:0006555 9 9 0,000 0,07584798 0,13493033 ! glutamine metabolic process GO:0006541 9 9 0,000 0,07584798 0,13480021 ! cerebral cortex development GO:0021987 9 9 0,000 0,07584798 0,13467035 ! response to osmotic stress GO:0006970 9 9 0,000 0,07584798 0,13454073 ! pigmentation during development GO:0048066 9 9 0,000 0,07584798 0,13441137 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,07584798 0,13428225 ! central nervous system neuron development GO:0021954 10 9 0,000 0,07584798 0,13415338 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,07584798 0,13402476 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,07584798 0,13389638 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,07584798 0,13376825 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,07584798 0,13364036 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,07584798 0,13351272 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,07584798 0,13338532 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,07584798 0,13325817 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,07584798 0,13313126 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,07584798 0,13300459 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,07584798 0,13287816 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,07584798 0,13275197 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,07584798 0,13262602 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,07584798 0,1325003 ! positive regulation of protein import into nucleus GO:0042307 9 9 0,000 0,07584798 0,13237483 ! DNA replication initiation GO:0006270 9 9 0,000 0,07584798 0,13224959 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,07584798 0,13212459 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,07584798 0,13199983 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,07584798 0,1318753 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,07584798 0,13175101 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,07584798 0,13162695 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,07584798 0,13150312 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,07584798 0,13137953 ! negative regulation of tissue remodeling GO:0034104 9 9 0,000 0,07584798 0,13125617 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,07584798 0,13113304 ! regulation of leukocyte migration GO:0002685 9 9 0,000 0,07584798 0,13101014 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,07584798 0,13088747 ! collagen catabolic process GO:0030574 9 9 0,000 0,07584798 0,13076503 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,07584798 0,13064282 ! purine base metabolic process GO:0006144 9 9 0,000 0,07584798 0,13052084 ! cholesterol efflux GO:0033344 9 9 0,000 0,07584798 0,13039909 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,07584798 0,13027756 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,07584798 0,13015626 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,07584798 0,13003518 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,07584798 0,12991433 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 0,000 0,07584798 0,12979371 ! defense response to virus GO:0051607 9 9 0,000 0,07584798 0,1296733 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,07584798 0,12955312 ! actin filament-based movement GO:0030048 9 9 0,000 0,07584798 0,12943317 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,07584798 0,12931343 ! regulation of protein transport GO:0051223 53 53 1,000 0,07766039 0,13228106 GO:0070201|regulation of establishment of protein localization, ! nucleosome organization GO:0034728 55 55 1,000 0,08278247 0,14087543 ! in utero embryonic development GO:0001701 55 55 1,000 0,08278247 0,14074547 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,083918 0,14254458 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,083918 0,14241333 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,083918 0,14228231 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,083918 0,14215154 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,083918 0,142021 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,083918 0,14189071 ! neuron maturation GO:0042551 10 10 0,000 0,083918 0,14176065 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,083918 0,14163083 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,083918 0,14150125 GO:0045767|regulation of anti-apoptosis, ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,083918 0,14137191 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,083918 0,1412428 ! hormone secretion GO:0046879 10 10 0,000 0,083918 0,14111393 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,083918 0,1409853 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,083918 0,1408569 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 0,000 0,083918 0,14072873 ! cAMP metabolic process GO:0046058 10 10 0,000 0,083918 0,14060079 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,083918 0,14047309 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,083918 0,14034562 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,083918 0,14021838 ! glial cell development GO:0021782 10 10 0,000 0,083918 0,14009137 ! phototransduction GO:0007602 11 10 0,000 0,083918 0,13996459 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,083918 0,13983804 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,083918 0,13971172 ! fat cell differentiation GO:0045444 10 10 0,000 0,083918 0,13958562 ! myoblast differentiation GO:0045445 10 10 0,000 0,083918 0,13945976 ! centrosome cycle GO:0007098 10 10 0,000 0,083918 0,13933412 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,083918 0,1392087 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,083918 0,13908352 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,083918 0,13895855 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,083918 0,13883382 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,083918 0,1387093 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,083918 0,13858501 ! protein polyubiquitination GO:0000209 10 10 0,000 0,083918 0,13846094 ! glutamate metabolic process GO:0006536 11 10 0,000 0,083918 0,13833709 ! plasma membrane organization GO:0007009 10 10 0,000 0,083918 0,13821347 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,083918 0,13809006 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-substrate junction assembly GO:0007044 11 10 0,000 0,083918 0,13796688 ! lysosomal transport GO:0007041 10 10 0,000 0,083918 0,13784391 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,083918 0,13772117 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,083918 0,13759864 ! vesicle coating GO:0006901 10 10 0,000 0,083918 0,13747633 ! exocrine system development GO:0035272 10 10 0,000 0,083918 0,13735424 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,083918 0,13723236 ! embryo implantation GO:0007566 11 10 0,000 0,083918 0,1371107 ! regulation of protein binding GO:0043393 11 10 0,000 0,083918 0,13698926 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,083918 0,13686803 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,083918 0,13674701 GO:0070585|protein localization in mitochondrion, ! protein export from nucleus GO:0006611 10 10 0,000 0,083918 0,13662621 ! negative regulation of immune response GO:0050777 10 10 0,000 0,083918 0,13650562 ! cytolysis GO:0019835 10 10 0,000 0,083918 0,13638525 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,083918 0,13626508 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,083918 0,13614513 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,083918 0,13602539 ! histone deacetylation GO:0016575 10 10 0,000 0,083918 0,13590586 ! mRNA splice site selection GO:0006376 11 10 0,000 0,083918 0,13578654 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,083918 0,13566743 ! gland morphogenesis GO:0022612 10 10 0,000 0,083918 0,13554853 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,083918 0,13542983 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,083918 0,13531135 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,083918 0,13519307 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,083918 0,135075 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,083918 0,13495713 ! regulation of epidermis development GO:0045682 10 10 0,000 0,083918 0,13483947 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,083918 0,13472201 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,083918 0,13460476 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,083918 0,13448771 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,083918 0,13437087 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,083918 0,13425423 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,083918 0,13413779 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 0,083918 0,13402155 ! gut development GO:0048565 10 10 0,000 0,083918 0,13390552 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,083918 0,13378968 ! negative regulation of homeostatic process GO:0032845 10 10 0,000 0,083918 0,13367405 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,083918 0,13355861 ! protein stabilization GO:0050821 10 10 0,000 0,083918 0,13344337 ! reproductive developmental process GO:0003006 56 56 1,000 0,0853819 0,13565417 ! regulation of binding GO:0051098 60 57 1,000 0,0880061 0,13970305 ! regulation of protein localization GO:0032880 58 57 1,000 0,0880061 0,13958283 ! protein secretion GO:0009306 11 11 0,000 0,09191871 0,1456631 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,09191871 0,14553796 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,09191871 0,14541304 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,09191871 0,14528833 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,09191871 0,14516383 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,09191871 0,14503955 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,09191871 0,14491548 ! skin development GO:0043588 11 11 0,000 0,09191871 0,14479162 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,09191871 0,14466797 ! signal complex assembly GO:0007172 11 11 0,000 0,09191871 0,14454453 ! peroxisomal transport GO:0043574 11 11 0,000 0,09191871 0,14442131 ! protein amino acid methylation GO:0006479 11 11 0,000 0,09191871 0,14429829 GO:0008213|protein amino acid alkylation, ! heart contraction GO:0060047 11 11 0,000 0,09191871 0,14417548 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,09191871 0,14405288 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,09191871 0,14393049 ! T cell proliferation GO:0042098 11 11 0,000 0,09191871 0,14380831 ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,09191871 0,14368634 ! spinal cord development GO:0021510 11 11 0,000 0,09191871 0,14356457 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,09191871 0,14344301 ! smooth muscle contraction GO:0006939 11 11 0,000 0,09191871 0,14332165 ! digestive system process GO:0022600 11 11 0,000 0,09191871 0,1432005 ! mitotic spindle organization GO:0007052 11 11 0,000 0,09191871 0,14307955 ! fucose metabolic process GO:0006004 11 11 0,000 0,09191871 0,14295881 ! membrane budding GO:0006900 11 11 0,000 0,09191871 0,14283827 ! monoamine transport GO:0015844 11 11 0,000 0,09191871 0,14271794 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,09191871 0,1425978 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,09191871 0,14247787 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,09191871 0,14235814 GO:0060415|muscle tissue morphogenesis, ! membrane depolarization GO:0051899 11 11 0,000 0,09191871 0,14223862 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,09191871 0,14211929 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,09191871 0,14200016 ! oogenesis GO:0048477 11 11 0,000 0,09191871 0,14188123 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,09191871 0,1417625 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,09191871 0,14164397 ! muscle maintenance GO:0046716 12 11 0,000 0,09191871 0,14152564 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,09191871 0,14140751 ! steroid catabolic process GO:0006706 11 11 0,000 0,09191871 0,14128957 ! endocrine process GO:0050886 11 11 0,000 0,09191871 0,14117183 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,09191871 0,14105428 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,09191871 0,14093693 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,09191871 0,14081978 ! carboxylic acid transport GO:0046942 59 59 1,000 0,09332636 0,14285755 GO:0015849|organic acid transport, ! protein localization in organelle GO:0033365 59 59 1,000 0,09332636 0,14273899 ! proteasomal protein catabolic process GO:0010498 62 61 1,000 0,09873846 0,15089136 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! carboxylic acid catabolic process GO:0046395 63 61 1,000 0,09873846 0,15076634 GO:0016054|organic acid catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 1,000 0,09873846 0,15064154 ! positive regulation of protein catabolic process GO:0045732 12 12 0,000 0,09985071 0,15221246 ! translational initiation GO:0006413 12 12 0,000 0,09985071 0,15208666 ! initiation of viral infection GO:0019059 12 12 0,000 0,09985071 0,15196107 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,09985071 0,15183569 ! iron ion transport GO:0006826 13 12 0,000 0,09985071 0,15171052 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,09985071 0,15158555 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,09985071 0,15146079 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,09985071 0,15133623 ! collagen metabolic process GO:0032963 12 12 0,000 0,09985071 0,15121188 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,09985071 0,15108773 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,09985071 0,15096379 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,09985071 0,15084005 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,09985071 0,15071651 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,09985071 0,15059317 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,09985071 0,15047004 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,09985071 0,15034711 ! actomyosin structure organization GO:0031032 12 12 0,000 0,09985071 0,15022437 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,09985071 0,15010184 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,09985071 0,14997951 ! retinoid metabolic process GO:0001523 12 12 0,000 0,09985071 0,14985738 GO:0016101|diterpenoid metabolic process, ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,09985071 0,14973544 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,09985071 0,14961371 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,09985071 0,14949217 ! acute-phase response GO:0006953 12 12 0,000 0,09985071 0,14937083 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,09985071 0,14924968 ! vacuolar transport GO:0007034 12 12 0,000 0,09985071 0,14912873 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,09985071 0,14900798 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,09985071 0,14888743 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,09985071 0,14876706 ! osteoblast differentiation GO:0001649 12 12 0,000 0,09985071 0,1486469 ! male gonad development GO:0008584 12 12 0,000 0,09985071 0,14852692 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,09985071 0,14840714 ! renal system process GO:0003014 12 12 0,000 0,09985071 0,14828756 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,09985071 0,14816816 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,09985071 0,14804896 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,09985071 0,14792995 ! pallium development GO:0021543 13 12 0,000 0,09985071 0,14781113 ! cell fate determination GO:0001709 12 12 0,000 0,09985071 0,1476925 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,09985071 0,14757406 ! G1 phase GO:0051318 13 12 0,000 0,09985071 0,14745582 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,09985071 0,14733776 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,09985071 0,14721989 ! detection of light stimulus GO:0009583 13 12 0,000 0,09985071 0,14710221 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,09985071 0,14698471 ! hormone transport GO:0009914 12 12 0,000 0,09985071 0,14686741 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,09985071 0,14675029 ! heme biosynthetic process GO:0006783 12 12 0,000 0,09985071 0,14663335 ! spermatid differentiation GO:0048515 13 12 0,000 0,09985071 0,14651661 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,09985071 0,14640005 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,09985071 0,14628367 ! neural tube closure GO:0001843 13 12 0,000 0,09985071 0,14616748 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! morphogenesis of an epithelium GO:0002009 63 62 1,000 0,10147748 0,14843095 GO:0060429|epithelium development, ! axonogenesis GO:0007409 66 62 1,000 0,10147748 0,14831324 ! protein import GO:0017038 62 62 1,000 0,10147748 0,14819572 ! positive regulation of protein metabolic process GO:0051247 64 64 1,000 0,10701862 0,15616415 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 0,000 0,10771457 0,15705534 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,10771457 0,15693118 GO:0016444|somatic cell DNA recombination, ! phenol metabolic process GO:0018958 13 13 0,000 0,10771457 0,15680722 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,10771457 0,15668346 ! gluconeogenesis GO:0006094 13 13 0,000 0,10771457 0,15655989 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,10771457 0,15643652 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,10771457 0,15631334 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,10771457 0,15619036 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,10771457 0,15606757 ! regeneration GO:0031099 13 13 0,000 0,10771457 0,15594497 ! keratinization GO:0031424 13 13 0,000 0,10771457 0,15582256 ! post-embryonic development GO:0009791 14 13 0,000 0,10771457 0,15570035 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,10771457 0,15557833 ! patterning of blood vessels GO:0001569 13 13 0,000 0,10771457 0,15545649 ! vasculogenesis GO:0001570 13 13 0,000 0,10771457 0,15533485 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,10771457 0,1552134 ! regulation of innate immune response GO:0045088 13 13 0,000 0,10771457 0,15509214 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,10771457 0,15497107 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,10771457 0,15485019 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,10771457 0,1547295 ! autophagy GO:0006914 13 13 0,000 0,10771457 0,15460899 ! receptor metabolic process GO:0043112 14 13 0,000 0,10771457 0,15448867 ! actin filament bundle formation GO:0051017 13 13 0,000 0,10771457 0,15436854 ! ureteric bud development GO:0001657 13 13 0,000 0,10771457 0,1542486 ! regulation of endothelial cell migration GO:0010594 13 13 0,000 0,10771457 0,15412884 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,10771457 0,15400927 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,10771457 0,15388988 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,10771457 0,15377068 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,10771457 0,15365166 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,10771457 0,15353283 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,10771457 0,15341418 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,10771457 0,15329571 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,10771457 0,15317743 ! vasodilation GO:0042311 14 13 0,000 0,10771457 0,15305932 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,10771457 0,15294141 GO:0002708|positive regulation of lymphocyte mediated immunity, ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,10771457 0,15282367 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 0,10771457 0,15270611 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 0,000 0,10771457 0,15258873 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,10771457 0,15247154 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,10771457 0,15235452 ! immunoglobulin production GO:0002377 13 13 0,000 0,10771457 0,15223769 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,10771457 0,15212103 ! negative regulation of intracellular transport GO:0032387 13 13 0,000 0,10771457 0,15200455 ! cell-cell junction organization GO:0045216 13 13 0,000 0,10771457 0,15188825 ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,10771457 0,15177213 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,10771457 0,15165618 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,10771457 0,15154042 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,10771457 0,15142482 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,10771457 0,15130941 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,10771457 0,15119417 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,10771457 0,1510791 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,10771457 0,15096422 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,10771457 0,1508495 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,10771457 0,15073496 ! blastocyst development GO:0001824 13 13 0,000 0,10771457 0,15062059 ! telomere organization GO:0032200 13 13 0,000 0,10771457 0,1505064 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,10771457 0,15039238 ! regulation of amine transport GO:0051952 13 13 0,000 0,10771457 0,15027853 ! tissue homeostasis GO:0001894 13 13 0,000 0,10771457 0,15016486 GO:0048871|multicellular organismal homeostasis, ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,10771457 0,15005136 ! positive regulation of cellular component organization GO:0051130 65 65 1,000 0,10981962 0,15286825 ! polysaccharide metabolic process GO:0005976 69 66 1,000 0,11264017 0,15667611 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 1,000 0,11547975 0,16050465 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! Golgi vesicle transport GO:0048193 67 67 1,000 0,11547975 0,1603837 ! negative regulation of cell differentiation GO:0045596 68 67 1,000 0,11547975 0,16026293 ! neuron fate commitment GO:0048663 14 14 0,000 0,11551086 0,16018548 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,11551086 0,16006504 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,11551086 0,15994478 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,11551086 0,1598247 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,11551086 0,15970481 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,11551086 0,15958509 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,11551086 0,15946555 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,11551086 0,15934619 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,11551086 0,15922701 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,11551086 0,159108 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,11551086 0,15898918 ! vesicle docking GO:0048278 14 14 0,000 0,11551086 0,15887053 ! superoxide metabolic process GO:0006801 15 14 0,000 0,11551086 0,15875206 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,11551086 0,15863376 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,11551086 0,15851564 ! hair cycle GO:0042633 14 14 0,000 0,11551086 0,1583977 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,11551086 0,15827993 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,11551086 0,15816234 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,11551086 0,15804492 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,11551086 0,15792768 ! lysosome organization GO:0007040 14 14 0,000 0,11551086 0,15781061 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,11551086 0,15769371 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,11551086 0,15757699 ! peptide transport GO:0015833 14 14 0,000 0,11551086 0,15746043 ! primary neural tube formation GO:0014020 15 14 0,000 0,11551086 0,15734406 ! peptide cross-linking GO:0018149 14 14 0,000 0,11551086 0,15722785 ! regulation of behavior GO:0050795 14 14 0,000 0,11551086 0,15711181 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,11551086 0,15699595 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,11551086 0,15688026 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,11551086 0,15676473 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,11551086 0,15664938 ! formation of primary germ layer GO:0001704 14 14 0,000 0,11551086 0,1565342 GO:0001707|mesoderm formation, ! collagen fibril organization GO:0030199 14 14 0,000 0,11551086 0,15641918 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,11551086 0,15630434 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,11551086 0,15618966 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,11551086 0,15607515 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,11551086 0,15596081 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,11551086 0,15584664 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,11551086 0,15573263 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,11551086 0,15561879 ! chromatin assembly or disassembly GO:0006333 68 68 1,000 0,1183378 0,15931086 ! sensory perception of sound GO:0007605 71 69 1,000 0,12121381 0,16306355 GO:0050954|sensory perception of mechanical stimulus, ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,12324015 0,16566856 ! positive regulation of ossification GO:0045778 15 15 0,000 0,12324015 0,16554781 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,12324015 0,16542724 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,12324015 0,16530684 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,12324015 0,16518662 ! response to vitamin GO:0033273 15 15 0,000 0,12324015 0,16506657 ! regulation of transcription factor import into nucleus GO:0042990 15 15 0,000 0,12324015 0,1649467 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,12324015 0,164827 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,12324015 0,16470747 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,12324015 0,16458812 ! ovarian follicle development GO:0001541 15 15 0,000 0,12324015 0,16446894 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,12324015 0,16434993 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,12324015 0,16423109 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,12324015 0,16411243 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,12324015 0,16399394 ! heme metabolic process GO:0042168 15 15 0,000 0,12324015 0,16387561 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,12324015 0,16375746 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,12324015 0,16363948 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,12324015 0,16352167 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,12324015 0,16340403 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,12324015 0,16328656 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,12324015 0,16316925 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,12324015 0,16305212 ! phospholipid transport GO:0015914 15 15 0,000 0,12324015 0,16293515 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,12324015 0,16281835 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,12324015 0,16270172 ! glutathione metabolic process GO:0006749 16 15 0,000 0,12324015 0,16258525 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,12324015 0,16246896 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,12324015 0,16235282 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,12324015 0,16223686 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,12324015 0,16212106 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,12324015 0,16200542 ! protein homooligomerization GO:0051260 15 15 0,000 0,12324015 0,16188995 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,12324015 0,16177464 ! positive regulation of transport GO:0051050 71 70 1,000 0,12410727 0,16279694 ! cell part morphogenesis GO:0032990 75 70 1,000 0,12410727 0,16268115 ! translational elongation GO:0006414 71 71 1,000 0,12701766 0,16637779 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,13090302 0,17134536 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,13090302 0,17122375 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,13090302 0,17110232 ! learning GO:0007612 16 16 0,000 0,13090302 0,17098105 ! circadian rhythm GO:0007623 16 16 0,000 0,13090302 0,17085996 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,13090302 0,17073904 ! vacuole organization GO:0007033 16 16 0,000 0,13090302 0,17061829 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,13090302 0,17049771 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,13090302 0,17037731 ! vesicle targeting GO:0006903 17 16 0,000 0,13090302 0,17025707 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,13090302 0,170137 ! iron ion homeostasis GO:0055072 16 16 0,000 0,13090302 0,1700171 ! positive regulation of cell development GO:0010720 16 16 0,000 0,13090302 0,16989737 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,13090302 0,16977781 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,13090302 0,16965842 ! pentose metabolic process GO:0019321 16 16 0,000 0,13090302 0,16953919 ! fatty acid transport GO:0015908 16 16 0,000 0,13090302 0,16942013 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,13090302 0,16930124 ! cofactor catabolic process GO:0051187 16 16 0,000 0,13090302 0,16918252 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,13090302 0,16906396 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,13090302 0,16894556 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,13090302 0,16882734 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,13090302 0,16870928 GO:0001841|neural tube formation, ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,13090302 0,16859138 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,13090302 0,16847365 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,13090302 0,16835608 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,13850002 0,17800247 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,13850002 0,17787843 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,13850002 0,17775455 ! leukocyte adhesion GO:0007159 17 17 0,000 0,13850002 0,17763086 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,13850002 0,17750733 ! sensory perception of smell GO:0007608 17 17 0,000 0,13850002 0,17738398 ! glucose transport GO:0015758 17 17 0,000 0,13850002 0,17726079 ! cell junction assembly GO:0034329 18 17 0,000 0,13850002 0,17713778 ! tissue remodeling GO:0048771 17 17 0,000 0,13850002 0,17701494 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,13850002 0,17689227 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,13850002 0,17676976 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,13850002 0,17664743 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,13850002 0,17652527 ! neural crest cell development GO:0014032 19 17 0,000 0,13850002 0,17640328 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 0,13850002 0,17628145 ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,13850002 0,17615979 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,13850002 0,1760383 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,13850002 0,17591698 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,13850002 0,17579583 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,13850002 0,17567484 ! pigmentation GO:0043473 17 17 0,000 0,13850002 0,17555402 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,13850002 0,17543336 ! adult locomotory behavior GO:0008344 17 17 0,000 0,13850002 0,17531287 ! embryonic organ development GO:0048568 17 17 0,000 0,13850002 0,17519255 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,13850002 0,17507239 ! liver development GO:0001889 17 17 0,000 0,13850002 0,17495239 ! gene silencing GO:0016458 17 17 0,000 0,13850002 0,17483256 ! cell morphogenesis involved in differentiation GO:0000904 82 77 1,000 0,144808 0,18267019 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,14603171 0,18408786 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,14603171 0,18396203 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,14603171 0,18383637 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,14603171 0,18371089 ! membrane docking GO:0022406 18 18 0,000 0,14603171 0,18358557 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,14603171 0,18346043 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,14603171 0,18333545 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,14603171 0,18321065 ! hexose transport GO:0008645 18 18 0,000 0,14603171 0,18308602 GO:0015749|monosaccharide transport, ! cholesterol homeostasis GO:0042632 18 18 0,000 0,14603171 0,18296156 GO:0055092|sterol homeostasis, ! striated muscle contraction GO:0006941 18 18 0,000 0,14603171 0,18283726 ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,14603171 0,18271313 ! ceramide metabolic process GO:0006672 18 18 0,000 0,14603171 0,18258918 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,14603171 0,18246539 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,14603171 0,18234177 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,14603171 0,18221831 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,14603171 0,18209503 ! BMP signaling pathway GO:0030509 18 18 0,000 0,14603171 0,18197191 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,14603171 0,18184895 ! nuclear transport GO:0051169 79 79 1,000 0,15085165 0,18772424 GO:0006913|nucleocytoplasmic transport, ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,15349865 0,19088934 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,15349865 0,19076062 GO:0006956|complement activation, ! feeding behavior GO:0007631 19 19 0,000 0,15349865 0,19063208 ! regulation of endothelial cell proliferation GO:0001936 19 19 0,000 0,15349865 0,19050371 ! peroxisome organization GO:0007031 19 19 0,000 0,15349865 0,19037551 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,15349865 0,19024748 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,15349865 0,19011963 ! metanephros development GO:0001656 19 19 0,000 0,15349865 0,18999194 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,15349865 0,18986443 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,15349865 0,18973709 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,15349865 0,18960992 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,15349865 0,18948292 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,15349865 0,1893561 ! eye morphogenesis GO:0048592 19 19 0,000 0,15349865 0,18922944 ! regulation of cell shape GO:0008360 21 19 0,000 0,15349865 0,18910295 ! placenta development GO:0001890 19 19 0,000 0,15349865 0,18897662 ! response to heat GO:0009408 19 19 0,000 0,15349865 0,18885047 ! vesicle localization GO:0051648 20 19 0,000 0,15349865 0,18872449 ! MAPKKK cascade GO:0000165 82 81 1,000 0,15694598 0,1928343 ! lymphocyte activation GO:0046649 82 81 1,000 0,15694598 0,19270583 ! regulation of muscle development GO:0048634 21 20 0,000 0,16090137 0,19743091 ! negative regulation of binding GO:0051100 21 20 0,000 0,16090137 0,19729955 ! neural tube development GO:0021915 21 20 0,000 0,16090137 0,19716837 ! phagocytosis GO:0006909 21 20 0,000 0,16090137 0,19703736 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,16090137 0,19690652 ! protein targeting to membrane GO:0006612 22 20 0,000 0,16090137 0,19677586 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,16090137 0,19664537 ! chromatin remodeling GO:0006338 20 20 0,000 0,16090137 0,19651506 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,16090137 0,19638492 ! lipid oxidation GO:0034440 20 20 0,000 0,16090137 0,19625495 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,16090137 0,19612515 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,16090137 0,19599552 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,16090137 0,19586607 ! RNA modification GO:0009451 20 20 0,000 0,16090137 0,19573678 ! single fertilization GO:0007338 21 20 0,000 0,16090137 0,19560767 ! regulation of B cell activation GO:0050864 20 20 0,000 0,16090137 0,19547872 ! cellular amino acid derivative metabolic process GO:0006575 87 84 1,000 0,16617488 0,2017525 ! mRNA catabolic process GO:0006402 21 21 0,000 0,16824042 0,20412581 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,16824042 0,20399151 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! protein amino acid lipidation GO:0006497 21 21 0,000 0,16824042 0,2038574 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,16824042 0,20372346 ! Notch signaling pathway GO:0007219 22 21 0,000 0,16824042 0,20358969 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,16824042 0,2034561 ! ear morphogenesis GO:0042471 21 21 0,000 0,16824042 0,20332269 ! organic anion transport GO:0015711 21 21 0,000 0,16824042 0,20318945 ! cholesterol transport GO:0030301 21 21 0,000 0,16824042 0,20305639 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,16824042 0,2029235 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,16824042 0,20279078 GO:0032313|regulation of Rab GTPase activity, ! regulation of protein import into nucleus GO:0042306 21 21 0,000 0,16824042 0,20265824 ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,16824042 0,20252587 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,16824042 0,20239367 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,16824042 0,20226165 ! negative regulation of protein transport GO:0051224 21 21 0,000 0,16824042 0,20212979 ! regulation of cellular localization GO:0060341 86 85 1,000 0,16927279 0,20323762 ! nitrogen compound biosynthetic process GO:0044271 86 85 1,000 0,16927279 0,20310531 ! organophosphate metabolic process GO:0019637 87 86 1,000 0,17238083 0,20669998 GO:0006644|phospholipid metabolic process, ! RNA export from nucleus GO:0006405 22 22 0,000 0,17551635 0,21032291 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,17551635 0,21018625 ! regulation of ion transport GO:0043269 22 22 0,000 0,17551635 0,21004976 ! odontogenesis GO:0042476 22 22 0,000 0,17551635 0,20991345 ! cell junction organization GO:0034330 23 22 0,000 0,17551635 0,20977732 ! hormone-mediated signaling GO:0009755 22 22 0,000 0,17551635 0,20964137 ! maintenance of protein location in cell GO:0032507 23 22 0,000 0,17551635 0,20950559 ! ovulation cycle process GO:0022602 22 22 0,000 0,17551635 0,20936999 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,17551635 0,20923456 ! cell chemotaxis GO:0060326 23 22 0,000 0,17551635 0,20909931 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,17551635 0,20896423 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,17551635 0,20882933 ! male sex differentiation GO:0046661 22 22 0,000 0,17551635 0,2086946 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,17551635 0,20856005 ! biopolymer methylation GO:0043414 22 22 0,000 0,17551635 0,20842567 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,17551635 0,20829146 ! detection of external stimulus GO:0009581 23 22 0,000 0,17551635 0,20815742 ! neuron migration GO:0001764 22 22 0,000 0,17551635 0,20802356 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,17551635 0,20788987 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,17551635 0,20775635 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,17551635 0,207623 ! aerobic respiration GO:0009060 22 22 0,000 0,17551635 0,20748982 ! cytokine production GO:0001816 22 22 0,000 0,17551635 0,20735682 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,17551635 0,20722398 ! male gamete generation GO:0048232 90 88 1,000 0,17862567 0,21075999 GO:0007283|spermatogenesis, ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,18272968 0,21546436 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,18272968 0,2153266 ! viral infectious cycle GO:0019058 23 23 0,000 0,18272968 0,21518901 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,18272968 0,2150516 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,18272968 0,21491436 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,18272968 0,2147773 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,18272968 0,21464041 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,18272968 0,2145037 ! endocrine system development GO:0035270 23 23 0,000 0,18272968 0,21436716 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,18272968 0,21423079 ! female gonad development GO:0008585 23 23 0,000 0,18272968 0,2140946 ! lipid homeostasis GO:0055088 23 23 0,000 0,18272968 0,21395858 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,18272968 0,21382273 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,18272968 0,21368706 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,18988094 0,22190906 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,18988094 0,22176843 ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,18988094 0,22162798 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,18988094 0,22148771 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,18988094 0,22134762 ! ovulation cycle GO:0042698 24 24 0,000 0,18988094 0,2212077 ! fertilization GO:0009566 25 24 0,000 0,18988094 0,22106796 ! maintenance of protein location GO:0045185 25 24 0,000 0,18988094 0,2209284 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,18988094 0,22078901 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,18988094 0,2206498 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 1,000 0,1912195 0,22206524 ! positive regulation of immune system process GO:0002684 92 92 1,000 0,1912195 0,2219254 ! tissue morphogenesis GO:0048729 94 93 1,000 0,19438746 0,22546009 ! negative regulation of secretion GO:0051048 26 25 0,000 0,19697067 0,22831254 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,19697067 0,22816904 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,19697067 0,22802572 ! endosome transport GO:0016197 25 25 0,000 0,19697067 0,22788257 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,19697067 0,22773961 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,19697067 0,22759683 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,19697067 0,22745422 ! excretion GO:0007588 25 25 0,000 0,19697067 0,2273118 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,19697067 0,22716955 ! gastrulation GO:0007369 25 25 0,000 0,19697067 0,22702748 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,19697067 0,22688559 ! regulation of endocytosis GO:0030100 25 25 0,000 0,19697067 0,22674387 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,19697067 0,22660234 ! epidermis development GO:0008544 94 94 1,000 0,19756248 0,22714139 ! positive regulation of defense response GO:0031349 26 26 0,000 0,20399937 0,23439579 ! glycolysis GO:0006096 26 26 0,000 0,20399937 0,23424975 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,20399937 0,23410389 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,20399937 0,23395821 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,20399937 0,23381271 ! cellular defense response GO:0006968 26 26 0,000 0,20399937 0,2336674 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,20399937 0,23352226 ! regulation of protein secretion GO:0050708 26 26 0,000 0,20399937 0,23337731 ! germ cell development GO:0007281 27 26 0,000 0,20399937 0,23323253 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,20399937 0,23308794 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,20399937 0,23294352 ! maintenance of location in cell GO:0051651 27 26 0,000 0,20399937 0,23279928 ! endocytosis GO:0006897 99 98 1,000 0,21032621 0,2398708 GO:0010324|membrane invagination, ! blood circulation GO:0008015 99 98 1,000 0,21032621 0,23972245 GO:0003013|circulatory system process, ! regulation of system process GO:0044057 98 98 1,000 0,21032621 0,23957429 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,21096757 0,24015641 ! learning or memory GO:0007611 28 27 0,000 0,21096757 0,24000817 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,21096757 0,23986011 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,21096757 0,23971223 ! mesenchymal cell development GO:0014031 29 27 0,000 0,21096757 0,23956453 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! inner ear development GO:0048839 27 27 0,000 0,21096757 0,23941702 ! defense response to bacterium GO:0042742 27 27 0,000 0,21096757 0,23926968 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,21096757 0,23912253 ! cell growth GO:0016049 27 27 0,000 0,21096757 0,23897556 ! anti-apoptosis GO:0006916 100 99 1,000 0,21353134 0,24173112 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 1,000 0,21674148 0,24521458 ! hemopoiesis GO:0030097 104 100 1,000 0,21674148 0,24506414 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,21787578 0,24619562 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,21787578 0,24604477 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,21787578 0,2458941 ! carbohydrate transport GO:0008643 28 28 0,000 0,21787578 0,24574361 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,21787578 0,24559331 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,21787578 0,24544319 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,21787578 0,24529326 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,21787578 0,2451435 ! developmental growth GO:0048589 28 28 0,000 0,21787578 0,24499393 ! cartilage development GO:0051216 29 28 0,000 0,21787578 0,24484455 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,2247245 0,25238712 ! leukocyte migration GO:0050900 30 29 0,000 0,2247245 0,25223341 ! branching morphogenesis of a tube GO:0048754 29 29 0,000 0,2247245 0,25207989 ! antigen processing and presentation GO:0019882 29 29 0,000 0,2247245 0,25192656 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,2247245 0,25177341 ! tRNA processing GO:0008033 29 29 0,000 0,2247245 0,25162045 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,2247245 0,25146767 ! adult behavior GO:0030534 30 29 0,000 0,2247245 0,25131508 ! RNA catabolic process GO:0006401 30 30 0,000 0,23151424 0,25875121 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,23151424 0,2585944 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,23151424 0,25843777 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,23151424 0,25828133 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,23151424 0,25812508 ! positive regulation of response to external stimulus GO:0032103 30 30 0,000 0,23151424 0,25796902 ! response to temperature stimulus GO:0009266 30 30 0,000 0,23151424 0,25781314 ! regulation of ossification GO:0030278 30 30 0,000 0,23151424 0,25765746 ! vascular process in circulatory system GO:0003018 31 30 0,000 0,23151424 0,25750196 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,23151424 0,25734665 GO:0019724|B cell mediated immunity, ! vesicle organization GO:0016050 30 30 0,000 0,23151424 0,25719153 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,23151424 0,2570366 ! regulation of translational initiation GO:0006446 31 31 0,000 0,23824551 0,26435067 ! membrane fusion GO:0006944 31 31 0,000 0,23824551 0,26419162 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,23824551 0,26403275 ! ion transmembrane transport GO:0034220 31 31 0,000 0,23824551 0,26387408 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,23824551 0,2637156 ! digestion GO:0007586 31 31 0,000 0,23824551 0,2635573 ! regulation of heart contraction GO:0008016 31 31 0,000 0,23824551 0,2633992 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,23824551 0,26324129 ! camera-type eye development GO:0043010 31 31 0,000 0,23824551 0,26308356 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,23824551 0,26292603 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,23824551 0,26276868 ! cell redox homeostasis GO:0045454 32 32 0,000 0,24491878 0,2699673 ! glucose catabolic process GO:0006007 32 32 0,000 0,24491878 0,26980593 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,24491878 0,26964475 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,24491878 0,26948377 ! cell maturation GO:0048469 32 32 0,000 0,24491878 0,26932298 ! morphogenesis of a branching structure GO:0001763 32 32 0,000 0,24491878 0,26916238 ! nuclear export GO:0051168 32 32 0,000 0,24491878 0,26900198 ! kidney development GO:0001822 32 32 0,000 0,24491878 0,26884176 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,24491878 0,26868174 ! maintenance of location GO:0051235 33 32 0,000 0,24491878 0,2685219 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,25153456 0,2756113 ! activation of protein kinase activity GO:0032147 35 33 0,000 0,25153456 0,27544754 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,25153456 0,27528397 ! regulation of bone remodeling GO:0046850 34 34 0,000 0,25809334 0,28229438 ! response to metal ion GO:0010038 34 34 0,000 0,25809334 0,28212694 ! ear development GO:0043583 34 34 0,000 0,25809334 0,28195971 ! muscle cell differentiation GO:0042692 35 34 0,000 0,25809334 0,28179267 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,25809334 0,28162583 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,25809334 0,28145919 ! secondary metabolic process GO:0019748 34 34 0,000 0,25809334 0,28129274 ! detection of stimulus GO:0051606 36 34 0,000 0,25809334 0,28112649 ! acute inflammatory response GO:0002526 35 35 0,000 0,26459559 0,28803879 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,26459559 0,28786875 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,26459559 0,28769892 GO:0048609|reproductive process in a multicellular organism, ! regulation of cell morphogenesis GO:0022604 38 35 0,000 0,26459559 0,28752929 ! regulation of tissue remodeling GO:0034103 35 35 0,000 0,26459559 0,28735985 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,26459559 0,28719062 ! regulation of immune effector process GO:0002697 35 35 0,000 0,26459559 0,28702158 ! hydrogen transport GO:0006818 36 36 0,000 0,27104179 0,29384119 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,27104179 0,29366844 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,27104179 0,2934959 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,27104179 0,29332356 ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,27104179 0,29315142 GO:0035113|embryonic appendage morphogenesis, ! female pregnancy GO:0007565 37 36 0,000 0,27104179 0,29297949 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,27104179 0,29280775 ! gonad development GO:0008406 36 36 0,000 0,27104179 0,29263622 ! activation of immune response GO:0002253 36 36 0,000 0,27104179 0,29246488 ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,27743243 0,29918546 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,27743243 0,2990105 ! eye development GO:0001654 37 37 0,000 0,27743243 0,29883574 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,27743243 0,29866119 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,27743243 0,29848684 ! adaptive immune response GO:0002250 37 37 0,000 0,27743243 0,2983127 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of secretion GO:0051047 39 38 0,000 0,28376796 0,30494714 ! neurotransmitter transport GO:0006836 40 38 0,000 0,28376796 0,30476943 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,28376796 0,30459193 ! exocytosis GO:0006887 40 38 0,000 0,28376796 0,30441464 ! urogenital system development GO:0001655 38 38 0,000 0,28376796 0,30423755 ! hexose catabolic process GO:0019320 38 38 0,000 0,28376796 0,30406067 ! RNA elongation GO:0006354 38 38 0,000 0,28376796 0,30388399 ! regulation of homeostatic process GO:0032844 38 38 0,000 0,28376796 0,30370752 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,29004886 0,31024959 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,29004886 0,31006963 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,29004886 0,30988988 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,29004886 0,30971034 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,29004886 0,30953101 ! developmental maturation GO:0021700 39 39 0,000 0,29004886 0,30935188 ! limb development GO:0060173 39 39 0,000 0,29004886 0,30917296 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,29627559 0,3156277 ! DNA catabolic process GO:0006308 41 40 0,000 0,29627559 0,31544536 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,29627559 0,31526323 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,30244861 0,32164616 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,30244861 0,32146066 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,30244861 0,32127538 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,30244861 0,32109032 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,30244861 0,32090546 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,30244861 0,32072082 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,30856838 0,32702215 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,30856838 0,32683421 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,30856838 0,32664648 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,30856838 0,32645897 ! protein ubiquitination GO:0016567 43 42 0,000 0,30856838 0,32627167 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,30856838 0,32608459 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! one-carbon metabolic process GO:0006730 42 42 0,000 0,30856838 0,32589772 ! reproductive structure development GO:0048608 43 43 0,000 0,31463534 0,33211508 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,31463534 0,33192498 ! alcohol catabolic process GO:0046164 43 43 0,000 0,31463534 0,33173509 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,31463534 0,33154542 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,31463534 0,33135596 ! humoral immune response GO:0006959 44 44 0,000 0,32064995 0,33749735 ! mRNA transport GO:0051028 44 44 0,000 0,32064995 0,33730471 ! amine biosynthetic process GO:0009309 46 45 0,000 0,32661265 0,34338112 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,32661265 0,34318535 ! protein processing GO:0016485 45 45 0,000 0,32661265 0,34298981 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,33252388 0,34899858 ! tube morphogenesis GO:0035239 47 46 0,000 0,33252388 0,34879995 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,33252388 0,34860154 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,33838407 0,3545434 ! regulation of blood pressure GO:0008217 48 47 0,000 0,33838407 0,35434196 ! sex differentiation GO:0007548 47 47 0,000 0,33838407 0,35414074 ! rhythmic process GO:0048511 47 47 0,000 0,33838407 0,35393975 ! calcium ion transport GO:0006816 48 48 0,000 0,34419366 0,35981221 ! DNA recombination GO:0006310 48 48 0,000 0,34419366 0,35960823 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,34995309 0,36541844 ! divalent metal ion transport GO:0070838 49 49 0,000 0,34995309 0,36521152 ! response to bacterium GO:0009617 50 49 0,000 0,34995309 0,36500483 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,34995309 0,36479838 ! negative regulation of transport GO:0051051 51 50 0,000 0,35566277 0,37054069 ! chromatin assembly GO:0031497 50 50 0,000 0,35566277 0,37033134 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,35566277 0,37012223 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! transcription initiation GO:0006352 50 50 0,000 0,35566277 0,36991336 ! anatomical structure homeostasis GO:0060249 51 50 0,000 0,35566277 0,36970473 ! protein modification by small protein conjugation GO:0032446 52 51 0,000 0,36132312 0,37537684 ! positive regulation of immune response GO:0050778 51 51 0,000 0,36132312 0,37516536 ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,36132312 0,37495412 ! ATP biosynthetic process GO:0006754 51 51 0,000 0,36132312 0,37474311 ! protein maturation GO:0051604 51 51 0,000 0,36132312 0,37453235 ! RNA localization GO:0006403 52 52 0,000 0,36693458 0,38013514 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,36693458 0,37992159 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,36693458 0,37970827 ! tRNA metabolic process GO:0006399 53 53 0,000 0,37249754 0,38524858 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,37249754 0,38503251 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,37249754 0,38481669 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,37249754 0,3846011 ! response to virus GO:0009615 54 54 0,000 0,37801243 0,39007666 ! hormone metabolic process GO:0042445 55 54 0,000 0,37801243 0,38985837 ! sulfur metabolic process GO:0006790 55 54 0,000 0,37801243 0,38964033 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,38347965 0,39505478 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! protein modification by small protein conjugation or removal GO:0070647 56 55 0,000 0,38347965 0,39483408 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,38889961 0,40019094 ! ATP metabolic process GO:0046034 57 57 0,000 0,39427271 0,40549364 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,39427271 0,40526749 ! innate immune response GO:0045087 58 58 0,000 0,39959934 0,41051371 ! sterol metabolic process GO:0016125 59 59 0,000 0,40487991 0,41570679 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,40487991 0,41547532 ! immune effector process GO:0002252 59 59 0,000 0,40487991 0,41524412 ! potassium ion transport GO:0006813 60 60 0,000 0,41011481 0,42037908 ! cellular respiration GO:0045333 62 61 0,000 0,41530441 0,42546194 ! lipid transport GO:0006869 62 62 0,000 0,42044912 0,43049318 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,42044912 0,43025415 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,42044912 0,43001538 ! regulation of secretion GO:0051046 65 63 0,000 0,4255493 0,43499022 ! glucose metabolic process GO:0006006 63 63 0,000 0,4255493 0,43474909 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,4255493 0,43450823 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,4255493 0,43426764 ! regulation of hormone levels GO:0010817 66 65 0,000 0,43561762 0,44429622 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,4405865 0,44911556 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,4405865 0,44886729 ! muscle contraction GO:0006936 67 67 0,000 0,44551236 0,45363496 ! Ras protein signal transduction GO:0007265 69 67 0,000 0,44551236 0,45338448 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,45039557 0,45810101 ! growth GO:0040007 70 70 0,000 0,46003545 0,46764773 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,46003545 0,46738993 GO:0016053|organic acid biosynthetic process, ! oxidative phosphorylation GO:0006119 71 71 0,000 0,46479284 0,4719632 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,46479284 0,47170331 GO:0006874|cellular calcium ion homeostasis, ! secretion by cell GO:0032940 75 72 0,000 0,46950902 0,47622736 ! muscle system process GO:0003012 72 72 0,000 0,46950902 0,47596541 ! sensory organ development GO:0007423 72 72 0,000 0,46950902 0,47570375 ! regulation of cytokine production GO:0001817 72 72 0,000 0,46950902 0,47544237 ! electron transport chain GO:0022900 75 74 0,000 0,4788191 0,48460384 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,4788191 0,48433787 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,4834137 0,4887172 ! response to oxidative stress GO:0006979 76 75 0,000 0,4834137 0,48844926 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,4834137 0,48818162 ! positive regulation of multicellular organismal process GO:0051240 76 76 0,000 0,48796847 0,49251144 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,49248374 0,49679667 ! metal ion homeostasis GO:0055065 78 78 0,000 0,49695985 0,50103774 ! regulation of immune response GO:0050776 78 78 0,000 0,49695985 0,5007638 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,50579592 0,50938901 ! lipid catabolic process GO:0016042 82 81 0,000 0,51015654 0,51350001 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,51876459 0,52187945 ! positive regulation of response to stimulus GO:0048584 86 85 0,000 0,52722385 0,53010014 ! hexose metabolic process GO:0019318 87 86 0,000 0,53139848 0,53400621 ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,53963927 0,54199193 ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 0,000 0,54370607 0,54577902 ! regulation of Ras protein signal transduction GO:0046578 90 90 0,000 0,54773752 0,54952654 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 0,000 0,55173395 0,55323486 ! visual perception GO:0007601 93 92 0,000 0,55569565 0,55690434 GO:0050953|sensory perception of light stimulus, ! fatty acid metabolic process GO:0006631 93 92 0,000 0,55569565 0,55660168 ! cofactor metabolic process GO:0051186 95 94 0,000 0,56351604 0,56412822 ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,57875293 0,57906712 ! response to other organism GO:0051707 101 100 0,000 0,586174 0,586174