Study Desmedt-ER-neg

Study informations

165 subnetworks in total page | file

2310 genes associated page | file

Enriched GO terms page

General informations

General Index page

Study Index page

Subnetwork 6311

score

Expression data for subnetwork 6311 in each dataset

IPC | Loi | Schmidt | VanDeVijver | Wang |

Subnetwork structure for each dataset

Score for each gene in subnetwork 6311 in each dataset

Gene Symbol	Links	Frequency	Frequency Rank	Subnetwork score rank	Global rank	IPC	Loi	Schmidt	VanDeVijver	Wang
EP300		113	4	1	4	-0.149	0.087	0.102	0.052	0.025
TEK		18	86	83	95	-0.149	-0.049	0.174	0.015	0.113
NUP188		8	222	1116	1079	-0.187	0.094	0.058	0.161	-0.070
HOXB7		6	301	1	52	0.267	-0.139	-0.083	0.085	-0.051
TSC2		2	743	2129	2103	0.236	0.044	0.114	0.001	-0.102
TP53		85	7	1	6	-0.167	0.148	-0.027	0.252	0.147
MDM4		9	196	141	147	-0.016	0.004	0.164	0.107	0.105
TAP1		2	743	1922	1902	0.210	-0.116	-0.118	-0.078	-0.146
ERBB2		141	1	1	1	-0.103	0.092	-0.090	0.267	0.046
MYH9		4	440	1131	1108	-0.103	0.227	0.007	-0.150	0.165
CDKN1A		110	5	1	5	0.064	0.254	0.030	undef	0.082
PRKCA		63	15	1	10	-0.016	-0.088	0.174	0.095	0.005
NLE1		3	557	882	871	0.138	-0.086	-0.018	0.001	0.044
PHLDA1		2	743	696	717	-0.036	-0.020	0.122	-0.119	0.053
TRIM68		1	1195	2188	2195	-0.221	0.109	-0.099	0.323	-0.011
DST		22	69	1	25	-0.094	0.343	0.065	-0.062	0.194
EXOC1		1	1195	2188	2195	undef	undef	undef	0.132	undef
MDM2		1	1195	2188	2195	-0.110	-0.038	0.113	0.001	-0.108
CCNA2		21	73	179	183	0.176	-0.053	0.188	-0.078	0.246
GP1BA		2	743	1165	1163	-0.106	0.001	0.101	0.001	-0.024
CTGF		32	40	318	290	-0.169	0.181	0.126	0.101	0.209
PMAIP1		4	440	1055	1035	0.118	-0.105	0.057	undef	-0.047
PIN1		24	62	179	181	0.194	0.040	-0.040	0.065	-0.048
UBE2U		2	743	1846	1832	-0.113	0.255	undef	undef	undef
TWIST1		50	20	1	14	0.044	0.194	0.061	undef	0.219
PPP2R2B		39	29	179	173	0.124	-0.019	0.029	0.116	-0.073
ACOX2		3	557	412	430	0.013	0.100	-0.021	0.134	0.047
KIT		39	29	1	18	-0.130	-0.091	0.235	-0.046	-0.059
PDGFRB		12	140	141	142	-0.094	0.224	0.127	0.153	0.189
GABPA		23	66	696	665	0.033	-0.183	0.066	0.141	-0.161
AKT2		28	47	412	394	0.110	-0.118	-0.003	0.088	-0.092
MKI67		5	360	1	56	0.205	-0.123	0.176	-0.086	0.018
KIF15		2	743	1	66	0.179	-0.188	0.138	-0.126	0.010
ATXN1		17	95	1	29	0.026	0.192	0.175	0.125	0.163
PTPN22		5	360	957	938	-0.086	-0.137	-0.292	0.148	-0.151
SMC2		4	440	83	112	0.202	-0.108	0.119	0.132	0.079
FLNA		50	20	1	14	0.081	0.107	0.148	0.268	0.126
VEGFA		68	14	83	78	0.090	0.200	0.030	0.095	0.148
SMYD2		4	440	1364	1330	0.260	0.068	0.179	0.014	0.191
ADM		10	167	682	653	0.255	0.187	0.091	0.169	0.212
RALA		10	167	318	323	0.224	0.207	-0.047	0.169	0.146
EDN2		3	557	1116	1107	0.153	0.062	0.132	0.196	0.287
TRIM34		1	1195	2188	2195	-0.111	0.186	-0.239	undef	0.110
AREG		5	360	1141	1109	-0.067	0.112	0.076	-0.173	-0.054
PAM		10	167	638	621	-0.035	0.307	0.200	0.002	0.104
RPL14		1	1195	2188	2195	-0.067	0.066	0.293	-0.358	-0.189
GSK3B		79	8	179	169	-0.130	0.292	-0.129	0.291	0.057
KLF5		76	9	1	7	0.077	0.117	-0.007	-0.110	-0.006
DSG1		10	167	658	636	0.072	-0.075	0.252	-0.061	0.068
UBE2E3		2	743	2188	2166	-0.040	0.003	0.040	0.149	-0.137
TRPC5		1	1195	2188	2195	undef	-0.019	-0.127	-0.011	-0.092
G3BP1		7	256	1116	1082	0.060	-0.077	-0.017	0.155	-0.004
TGFB1I1		49	22	1	16	-0.105	0.229	0.143	0.195	0.298
HIVEP1		6	301	764	758	-0.199	0.069	0.000	0.193	-0.042
MKI67IP		2	743	1803	1782	0.190	-0.123	undef	undef	undef
GRB14		24	62	179	181	0.113	-0.129	0.143	-0.098	0.138
CHIC2		2	743	727	734	0.128	-0.154	0.120	0.154	-0.008
GSTT1		15	111	1	32	0.148	0.107	-0.190	0.022	-0.064
NCAPG		3	557	83	117	0.253	-0.183	0.065	undef	0.020
KRT81		2	743	2080	2055	0.108	-0.105	0.252	0.053	0.086
JUN		26	52	179	177	0.200	0.051	0.220	undef	0.200
RECQL4		2	743	1830	1815	0.039	-0.211	0.069	-0.095	-0.053
SLC9A3R1		3	557	1735	1718	0.004	0.017	0.017	0.096	-0.110
PTEN		27	50	141	135	0.045	0.055	0.017	0.183	-0.041
AMH		10	167	366	362	0.103	0.056	0.113	-0.187	0.301
BCL2		37	32	83	82	-0.077	-0.035	0.128	-0.106	0.043
ARHGAP1		6	301	179	205	-0.167	0.297	0.001	-0.032	0.251
MYCN		7	256	764	756	0.125	0.057	-0.003	-0.081	-0.084
STXBP1		5	360	1629	1587	-0.027	0.078	0.180	0.143	0.043
REV1		9	196	296	285	0.090	-0.027	0.165	0.049	0.039
AKAP11		4	440	457	458	-0.034	-0.099	-0.038	0.251	0.017
MDFI		17	95	236	226	-0.075	-0.001	0.177	0.169	-0.112
ORC2L		1	1195	2188	2195	-0.122	-0.159	-0.111	0.125	0.020
POLK		3	557	806	792	0.120	0.046	undef	0.113	undef
PIK3R1		127	2	1	2	-0.237	0.381	0.065	undef	-0.002
GTPBP4		4	440	882	870	0.129	-0.179	0.076	-0.043	-0.026
R3HDM2		2	743	1055	1059	-0.085	-0.001	undef	undef	undef
RNF8		2	743	1688	1673	0.216	0.004	0.114	-0.088	0.221
IRS4		32	40	236	224	0.115	-0.111	-0.088	0.096	0.142
EGFR		117	3	1	3	-0.195	0.240	-0.205	-0.187	0.065
ECH1		2	743	882	892	0.065	-0.008	-0.070	0.193	-0.017
MAP1B		69	12	1	9	-0.123	0.263	-0.107	0.304	0.100
PTPRC		9	196	83	99	-0.031	-0.204	-0.050	-0.179	-0.068
NEK1		15	111	141	139	0.032	0.184	0.049	undef	0.135
PKN3		18	86	179	187	-0.181	0.009	undef	0.239	undef
AKT3		5	360	1083	1066	0.172	-0.058	0.087	0.121	0.080
AR		46	24	141	133	-0.163	0.081	-0.035	0.178	-0.030
TIE1		18	86	366	357	-0.108	0.005	0.141	-0.108	0.252
PLD1		17	95	1	29	0.132	0.033	-0.158	-0.062	0.123
ITGB4		35	34	1	20	0.021	0.313	-0.134	0.080	-0.114
CDK2		31	43	179	174	0.196	-0.096	0.109	0.001	0.362
CBX5		5	360	1	56	0.155	0.016	0.148	0.030	-0.009
RALGPS1		1	1195	2188	2195	-0.082	0.121	0.072	0.244	0.016
RABEP1		2	743	366	395	-0.004	0.239	0.060	0.060	0.008
MME		5	360	1047	1021	-0.121	0.020	0.088	-0.002	-0.130
CDKN2A		60	17	1	11	0.263	-0.113	0.111	undef	-0.105

GO Enrichment output for subnetwork 6311 in each dataset

IPC file

Name	Accession Number	Link	P-val	Corrected P-val
regulation of protein stability	GO:0031647		5.737E-12	1.401E-08
negative regulation of protein kinase B signaling cascade	GO:0051898		1.069E-10	1.305E-07
negative regulation of phosphorylation	GO:0042326		2.733E-10	2.226E-07
negative regulation of phosphorus metabolic process	GO:0010563		5.132E-10	3.134E-07
platelet-derived growth factor receptor signaling pathway	GO:0048008		1.454E-09	7.106E-07
regulation of protein kinase B signaling cascade	GO:0051896		4.385E-09	1.785E-06
regulation of cyclin-dependent protein kinase activity	GO:0000079		7.438E-09	2.596E-06
negative regulation of cell-matrix adhesion	GO:0001953		7.992E-09	2.441E-06
regulation of cell-matrix adhesion	GO:0001952		1.144E-08	3.106E-06
phospholipid dephosphorylation	GO:0046839		1.266E-08	3.094E-06
negative regulation of protein amino acid phosphorylation	GO:0001933		3.403E-08	7.558E-06

Loi file

Name	Accession Number	Link	P-val	Corrected P-val
regulation of protein stability	GO:0031647		7.802E-12	1.877E-08
negative regulation of protein kinase B signaling cascade	GO:0051898		1.483E-10	1.784E-07
negative regulation of phosphorylation	GO:0042326		4.285E-10	3.436E-07
negative regulation of phosphorus metabolic process	GO:0010563		8.038E-10	4.835E-07
platelet-derived growth factor receptor signaling pathway	GO:0048008		2.144E-09	1.032E-06
regulation of protein kinase B signaling cascade	GO:0051896		6.075E-09	2.436E-06
negative regulation of cell-matrix adhesion	GO:0001953		1.107E-08	3.804E-06
regulation of cyclin-dependent protein kinase activity	GO:0000079		1.226E-08	3.689E-06
phospholipid dephosphorylation	GO:0046839		1.647E-08	4.403E-06
regulation of cell-matrix adhesion	GO:0001952		1.683E-08	4.049E-06
negative regulation of protein amino acid phosphorylation	GO:0001933		4.707E-08	1.03E-05

Schmidt file

Name	Accession Number	Link	P-val	Corrected P-val
regulation of protein stability	GO:0031647		6.123E-10	1.408E-06
negative regulation of phosphorylation	GO:0042326		1.627E-09	1.872E-06
negative regulation of phosphorus metabolic process	GO:0010563		3.139E-09	2.407E-06
platelet-derived growth factor receptor signaling pathway	GO:0048008		2.046E-08	1.176E-05
negative regulation of protein kinase B signaling cascade	GO:0051898		4.386E-08	2.018E-05
negative regulation of protein amino acid phosphorylation	GO:0001933		1.02E-07	3.91E-05
negative regulation of protein modification process	GO:0031400		1.57E-07	5.159E-05
induction of positive chemotaxis	GO:0050930		6.001E-07	1.725E-04
regulation of protein kinase B signaling cascade	GO:0051896		6.001E-07	1.534E-04
regulation of cyclin-dependent protein kinase activity	GO:0000079		6.105E-07	1.404E-04
apoptotic mitochondrial changes	GO:0008637		6.527E-07	1.365E-04

VanDeVijver file

Name	Accession Number	Link	P-val	Corrected P-val
regulation of cell migration	GO:0030334		1.495E-09	2.755E-06
regulation of locomotion	GO:0040012		4.379E-09	4.036E-06
regulation of cell motion	GO:0051270		4.379E-09	2.69E-06
regulation of protein stability	GO:0031647		1.997E-08	9.203E-06
platelet-derived growth factor receptor signaling pathway	GO:0048008		1.124E-06	4.144E-04
positive regulation of cell migration	GO:0030335		1.254E-06	3.852E-04
protein stabilization	GO:0050821		1.86E-06	4.896E-04
positive regulation of cell motion	GO:0051272		2.052E-06	4.726E-04
negative regulation of cell migration	GO:0030336		4.895E-06	1.002E-03
regulation of mitotic cell cycle	GO:0007346		4.934E-06	9.094E-04
positive regulation of MAP kinase activity	GO:0043406		8.128E-06	1.362E-03

Wang file

Name	Accession Number	Link	P-val	Corrected P-val
regulation of protein stability	GO:0031647		6.123E-10	1.408E-06
negative regulation of phosphorylation	GO:0042326		1.627E-09	1.872E-06
negative regulation of phosphorus metabolic process	GO:0010563		3.139E-09	2.407E-06
platelet-derived growth factor receptor signaling pathway	GO:0048008		2.046E-08	1.176E-05
negative regulation of protein kinase B signaling cascade	GO:0051898		4.386E-08	2.018E-05
negative regulation of protein amino acid phosphorylation	GO:0001933		1.02E-07	3.91E-05
negative regulation of protein modification process	GO:0031400		1.57E-07	5.159E-05
induction of positive chemotaxis	GO:0050930		6.001E-07	1.725E-04
regulation of protein kinase B signaling cascade	GO:0051896		6.001E-07	1.534E-04
regulation of cyclin-dependent protein kinase activity	GO:0000079		6.105E-07	1.404E-04
apoptotic mitochondrial changes	GO:0008637		6.527E-07	1.365E-04