Study run-a2

Study informations

103 subnetworks in total page | file

306 genes associated page | file

Enriched GO terms page

General informations

General Index page

Study Index page

Subnetwork 6712-8-real

score

Dataset	Score	P-val 1	P-val 2	P-val 3
Desmedt	0.1977	9.732e-03	7.263e-03	8.532e-02
IPC-NIBC-129	0.2502	3.867e-02	5.627e-02	3.764e-01
Ivshina_GPL96-GPL97	0.2512	1.138e-02	1.873e-02	2.923e-01
Loi_GPL570	0.3125	2.386e-02	2.767e-02	1.183e-01
Loi_GPL96-GPL97	0.1185	3.000e-06	3.000e-05	7.000e-06
Parker_GPL1390	0.2338	1.190e-02	1.575e-02	1.651e-01
Parker_GPL887	0.3390	3.647e-01	3.836e-01	3.984e-01
Pawitan_GPL96-GPL97	0.4133	4.514e-02	2.422e-02	3.251e-01
Schmidt	0.3417	3.048e-02	3.621e-02	3.084e-01
Sotiriou	0.3298	9.050e-03	6.902e-03	1.779e-01
Van-De-Vijver	0.2757	1.019e-03	1.467e-03	5.945e-02
Zhang	0.2450	2.478e-01	1.898e-01	4.568e-01
Zhou	0.4193	4.067e-02	2.876e-02	2.661e-01

Expression data for subnetwork 6712-8-real in each dataset

Desmedt | IPC-NIBC-129 | Ivshina_GPL96-GPL97 | Loi_GPL570 | Loi_GPL96-GPL97 | Parker_GPL1390 | Parker_GPL887 | Pawitan_GPL96-GPL97 | Schmidt | Sotiriou | Van-De-Vijver | Zhang | Zhou |

Subnetwork structure for each dataset

Desmedt IPC-NIBC-129 Ivshina_GPL96-GPL97 Loi_GPL570 Loi_GPL96-GPL97 Parker_GPL1390 Parker_GPL887 Pawitan_GPL96-GPL97 Schmidt Sotiriou Van-De-Vijver Zhang Zhou

Desmedt

Score for each gene in subnetwork 6712-8-real in each dataset

Gene Symbol	Links	Frequency	Frequency Rank	Subnetwork score rank	Global rank	Desmedt	IPC-NIBC-129	Ivshina_GPL96-GPL97	Loi_GPL570	Loi_GPL96-GPL97	Parker_GPL1390	Parker_GPL887	Pawitan_GPL96-GPL97	Schmidt	Sotiriou	Van-De-Vijver	Zhang	Zhou
sfrs3		2	78	1	18	-0.089	0.148	0.132	0.066	0.078	0.168	-0.112	-0.008	0.168	0.102	0.049	0.102	0.315
cttn		10	20	1	6	0.067	0.065	0.123	0.238	0.126	0.263	-0.172	0.216	0.069	0.115	undef	0.025	0.279
cdkn1a		44	7	1	4	0.115	-0.020	0.065	0.082	0.099	0.124	0.055	0.087	0.068	0.144	undef	-0.201	0.069
tle1		47	6	1	3	0.062	0.235	-0.032	-0.177	0.033	0.085	0.339	0.068	0.126	-0.027	0.170	0.068	0.025
mapk14		4	50	1	10	-0.062	0.058	0.135	0.204	0.086	0.061	0.389	0.068	0.246	0.068	0.076	0.011	0.192
snrpb		3	62	1	14	0.141	0.077	0.167	0.250	0.139	0.089	0.155	0.281	0.120	0.161	0.167	0.010	0.153
larp1		1	116	1	29	0.091	0.223	0.142	0.016	0.090	0.143	-0.050	0.217	0.201	0.242	undef	0.063	0.286
cdc2		96	1	1	1	0.073	0.247	0.206	0.172	0.247	0.153	-0.131	0.282	0.226	0.221	0.162	0.297	0.336
kcnk15		4	50	1	10	0.088	-0.091	-0.068	0.220	0.076	-0.136	0.026	0.083	0.037	0.154	undef	0.098	0.140
sptbn2		1	116	1	29	0.023	0.105	0.069	0.030	0.082	-0.017	0.562	0.172	0.023	0.062	0.079	0.049	0.159
nfatc4		15	11	1	5	0.094	-0.056	-0.021	0.204	0.079	-0.008	0.243	0.060	0.077	-0.012	0.136	0.131	0.154
celsr3		1	116	1	29	0.097	0.124	0.198	0.213	0.100	-0.091	0.450	0.148	0.106	0.103	undef	0.069	0.126
bax		3	62	1	14	0.029	0.185	0.233	0.192	0.088	-0.043	0.184	0.172	0.175	0.019	-0.029	0.041	0.235
ywhaq		5	40	1	9	0.129	0.110	0.049	0.116	0.071	0.160	-0.210	0.038	0.007	0.054	0.072	0.138	0.187
sfn		61	3	1	2	0.077	0.137	0.111	0.172	0.112	0.119	0.141	0.219	0.100	0.147	0.158	0.079	0.181
acta1		9	22	1	7	-0.003	0.098	-0.008	-0.030	0.119	0.174	0.376	0.024	0.182	0.214	0.100	0.048	0.201
grb2		9	22	1	7	0.084	-0.013	0.086	-0.031	0.162	-0.038	0.003	0.065	0.158	0.127	0.149	0.194	-0.005

GO Enrichment output for subnetwork 6712-8-real in each dataset

Desmedt file

Name	Accession Number	Link	P-val	Corrected P-val
skeletal myofibril assembly	GO:0014866		3.879E-05	0.08922299
induction of apoptosis by intracellular signals	GO:0008629		6.903E-05	0.07938827
regulation of protein homodimerization activity	GO:0043496		8.126E-05	0.06229904
negative regulation of cyclin-dependent protein kinase activity	GO:0045736		1.082E-04	0.06222068
positive regulation of B cell proliferation	GO:0030890		1.082E-04	0.04977654
keratinocyte proliferation	GO:0043616		1.082E-04	0.04148045
regulation of cyclin-dependent protein kinase activity	GO:0000079		1.433E-04	0.04709397
regulation of B cell proliferation	GO:0030888		1.735E-04	0.04987308
negative regulation of protein kinase activity	GO:0006469		1.997E-04	0.05104324
negative regulation of kinase activity	GO:0033673		2.103E-04	0.04837833
negative regulation of transferase activity	GO:0051348		2.443E-04	0.05108753

IPC-NIBC-129 file

Name	Accession Number	Link	P-val	Corrected P-val
skeletal myofibril assembly	GO:0014866		1.36E-05	0.0332245
induction of apoptosis by intracellular signals	GO:0008629		2.103E-05	0.02568614
regulation of protein homodimerization activity	GO:0043496		2.852E-05	0.02322227
regulation of cyclin-dependent protein kinase activity	GO:0000079		4.294E-05	0.02622266
negative regulation of cyclin-dependent protein kinase activity	GO:0045736		6.097E-05	0.02979008
positive regulation of B cell proliferation	GO:0030890		6.097E-05	0.02482507
keratinocyte proliferation	GO:0043616		7.446E-05	0.02598771
negative regulation of protein kinase activity	GO:0006469		7.613E-05	0.02324725
negative regulation of kinase activity	GO:0033673		7.947E-05	0.02157175
regulation of B cell proliferation	GO:0030888		8.929E-05	0.02181331
regulation of caspase activity	GO:0043281		9.38E-05	0.0208324

Ivshina_GPL96-GPL97 file

Name	Accession Number	Link	P-val	Corrected P-val
skeletal myofibril assembly	GO:0014866		1.803E-05	0.04339156
induction of apoptosis by intracellular signals	GO:0008629		3.193E-05	0.03841552
regulation of protein homodimerization activity	GO:0043496		3.781E-05	0.03032168
keratinocyte proliferation	GO:0043616		6.47E-05	0.03891776
regulation of cyclin-dependent protein kinase activity	GO:0000079		6.51E-05	0.03132801
negative regulation of cyclin-dependent protein kinase activity	GO:0045736		8.081E-05	0.03240348
positive regulation of B cell proliferation	GO:0030890		8.081E-05	0.02777441
negative regulation of protein kinase activity	GO:0006469		1.056E-04	0.0317553
negative regulation of kinase activity	GO:0033673		1.104E-04	0.02950183
regulation of B cell proliferation	GO:0030888		1.183E-04	0.02846588
positive regulation of cell growth	GO:0030307		1.183E-04	0.02587808

Loi_GPL570 file

Name	Accession Number	Link	P-val	Corrected P-val
skeletal myofibril assembly	GO:0014866		1.36E-05	0.0332245
induction of apoptosis by intracellular signals	GO:0008629		2.103E-05	0.02568614
regulation of protein homodimerization activity	GO:0043496		2.852E-05	0.02322227
regulation of cyclin-dependent protein kinase activity	GO:0000079		4.294E-05	0.02622266
negative regulation of cyclin-dependent protein kinase activity	GO:0045736		6.097E-05	0.02979008
positive regulation of B cell proliferation	GO:0030890		6.097E-05	0.02482507
keratinocyte proliferation	GO:0043616		7.446E-05	0.02598771
negative regulation of protein kinase activity	GO:0006469		7.613E-05	0.02324725
negative regulation of kinase activity	GO:0033673		7.947E-05	0.02157175
regulation of B cell proliferation	GO:0030888		8.929E-05	0.02181331
regulation of caspase activity	GO:0043281		9.38E-05	0.0208324

Loi_GPL96-GPL97 file

Name	Accession Number	Link	P-val	Corrected P-val
skeletal myofibril assembly	GO:0014866		1.803E-05	0.04339156
induction of apoptosis by intracellular signals	GO:0008629		3.193E-05	0.03841552
regulation of protein homodimerization activity	GO:0043496		3.781E-05	0.03032168
keratinocyte proliferation	GO:0043616		6.47E-05	0.03891776
regulation of cyclin-dependent protein kinase activity	GO:0000079		6.51E-05	0.03132801
negative regulation of cyclin-dependent protein kinase activity	GO:0045736		8.081E-05	0.03240348
positive regulation of B cell proliferation	GO:0030890		8.081E-05	0.02777441
negative regulation of protein kinase activity	GO:0006469		1.056E-04	0.0317553
negative regulation of kinase activity	GO:0033673		1.104E-04	0.02950183
regulation of B cell proliferation	GO:0030888		1.183E-04	0.02846588
positive regulation of cell growth	GO:0030307		1.183E-04	0.02587808

Parker_GPL1390 file

Name	Accession Number	Link	P-val	Corrected P-val
protein serine/threonine kinase inhibitor activity	GO:0030291		3.797E-07	1.356E-03
protein kinase inhibitor activity	GO:0004860		3.385E-06	6.045E-03
kinase inhibitor activity	GO:0019210		4.19E-06	4.988E-03
response to lipid	GO:0033993		1.104E-05	9.852E-03
skeletal myofibril assembly	GO:0014866		1.104E-05	7.881E-03
SAP kinase activity	GO:0016909		1.104E-05	6.568E-03
heart trabecula formation	GO:0060347		1.104E-05	5.629E-03
muscle cell proliferation	GO:0033002		1.104E-05	4.926E-03
type II transforming growth factor beta receptor binding	GO:0005114		1.104E-05	4.378E-03
induction of apoptosis by intracellular signals	GO:0008629		1.263E-05	4.509E-03
insulin receptor substrate binding	GO:0043560		1.654E-05	5.37E-03

Parker_GPL887 file

Name	Accession Number	Link	P-val	Corrected P-val
induction of apoptosis by intracellular signals	GO:0008629		1.153E-07	4.208E-04
release of cytochrome c from mitochondria	GO:0001836		4.393E-07	8.014E-04
protein serine/threonine kinase inhibitor activity	GO:0030291		6.749E-07	8.207E-04
apoptotic mitochondrial changes	GO:0008637		1.597E-06	1.457E-03
protein kinase inhibitor activity	GO:0004860		7.119E-06	5.194E-03
kinase inhibitor activity	GO:0019210		7.781E-06	4.731E-03
muscle thin filament assembly	GO:0030240		1.196E-05	6.234E-03
lymphocyte apoptosis	GO:0070227		1.196E-05	5.454E-03
RNA polymerase II carboxy-terminal domain kinase activity	GO:0008353		1.196E-05	4.848E-03
epidermal growth factor receptor binding	GO:0005154		1.196E-05	4.363E-03
skeletal myofibril assembly	GO:0014866		1.793E-05	5.946E-03

Pawitan_GPL96-GPL97 file

Name	Accession Number	Link	P-val	Corrected P-val
skeletal myofibril assembly	GO:0014866		1.803E-05	0.04339156
induction of apoptosis by intracellular signals	GO:0008629		3.193E-05	0.03841552
regulation of protein homodimerization activity	GO:0043496		3.781E-05	0.03032168
keratinocyte proliferation	GO:0043616		6.47E-05	0.03891776
regulation of cyclin-dependent protein kinase activity	GO:0000079		6.51E-05	0.03132801
negative regulation of cyclin-dependent protein kinase activity	GO:0045736		8.081E-05	0.03240348
positive regulation of B cell proliferation	GO:0030890		8.081E-05	0.02777441
negative regulation of protein kinase activity	GO:0006469		1.056E-04	0.0317553
negative regulation of kinase activity	GO:0033673		1.104E-04	0.02950183
regulation of B cell proliferation	GO:0030888		1.183E-04	0.02846588
positive regulation of cell growth	GO:0030307		1.183E-04	0.02587808

Schmidt file

Name	Accession Number	Link	P-val	Corrected P-val
skeletal myofibril assembly	GO:0014866		3.879E-05	0.08922299
induction of apoptosis by intracellular signals	GO:0008629		6.903E-05	0.07938827
regulation of protein homodimerization activity	GO:0043496		8.126E-05	0.06229904
negative regulation of cyclin-dependent protein kinase activity	GO:0045736		1.082E-04	0.06222068
positive regulation of B cell proliferation	GO:0030890		1.082E-04	0.04977654
keratinocyte proliferation	GO:0043616		1.082E-04	0.04148045
regulation of cyclin-dependent protein kinase activity	GO:0000079		1.433E-04	0.04709397
regulation of B cell proliferation	GO:0030888		1.735E-04	0.04987308
negative regulation of protein kinase activity	GO:0006469		1.997E-04	0.05104324
negative regulation of kinase activity	GO:0033673		2.103E-04	0.04837833
negative regulation of transferase activity	GO:0051348		2.443E-04	0.05108753

Sotiriou file

Name	Accession Number	Link	P-val	Corrected P-val
skeletal myofibril assembly	GO:0014866		3.879E-05	0.08922299
induction of apoptosis by intracellular signals	GO:0008629		6.903E-05	0.07938827
regulation of protein homodimerization activity	GO:0043496		8.126E-05	0.06229904
negative regulation of cyclin-dependent protein kinase activity	GO:0045736		1.082E-04	0.06222068
positive regulation of B cell proliferation	GO:0030890		1.082E-04	0.04977654
keratinocyte proliferation	GO:0043616		1.082E-04	0.04148045
regulation of cyclin-dependent protein kinase activity	GO:0000079		1.433E-04	0.04709397
regulation of B cell proliferation	GO:0030888		1.735E-04	0.04987308
negative regulation of protein kinase activity	GO:0006469		1.997E-04	0.05104324
negative regulation of kinase activity	GO:0033673		2.103E-04	0.04837833
negative regulation of transferase activity	GO:0051348		2.443E-04	0.05108753

Van-De-Vijver file

Name	Accession Number	Link	P-val	Corrected P-val
regulation of protein homodimerization activity	GO:0043496		2.781E-05	0.05125333
regulation of caspase activity	GO:0043281		4.164E-05	0.03837329
positive regulation of cell growth	GO:0030307		4.167E-05	0.02560183
regulation of endopeptidase activity	GO:0052548		4.48E-05	0.02064222
keratinocyte proliferation	GO:0043616		5.829E-05	0.02148469
myofibril assembly	GO:0030239		5.829E-05	0.01790391
regulation of peptidase activity	GO:0052547		5.901E-05	0.01553599
muscle cell development	GO:0055001		7.764E-05	0.01788656
release of cytochrome c from mitochondria	GO:0001836		7.764E-05	0.01589916
positive regulation of cell size	GO:0045793		9.973E-05	0.01837977
negative regulation of caspase activity	GO:0043154		9.973E-05	0.01670888

Zhang file

Name	Accession Number	Link	P-val	Corrected P-val
skeletal myofibril assembly	GO:0014866		3.879E-05	0.08922299
induction of apoptosis by intracellular signals	GO:0008629		6.903E-05	0.07938827
regulation of protein homodimerization activity	GO:0043496		8.126E-05	0.06229904
negative regulation of cyclin-dependent protein kinase activity	GO:0045736		1.082E-04	0.06222068
positive regulation of B cell proliferation	GO:0030890		1.082E-04	0.04977654
keratinocyte proliferation	GO:0043616		1.082E-04	0.04148045
regulation of cyclin-dependent protein kinase activity	GO:0000079		1.433E-04	0.04709397
regulation of B cell proliferation	GO:0030888		1.735E-04	0.04987308
negative regulation of protein kinase activity	GO:0006469		1.997E-04	0.05104324
negative regulation of kinase activity	GO:0033673		2.103E-04	0.04837833
negative regulation of transferase activity	GO:0051348		2.443E-04	0.05108753

Zhou file

Name	Accession Number	Link	P-val	Corrected P-val
spliceosomal snRNP biogenesis	GO:0000387		1.824E-05	0.04327557
skeletal myofibril assembly	GO:0014866		3.542E-05	0.04202614
induction of apoptosis by intracellular signals	GO:0008629		7.017E-05	0.05550667
regulation of protein homodimerization activity	GO:0043496		7.42E-05	0.04402104
negative regulation of cyclin-dependent protein kinase activity	GO:0045736		9.882E-05	0.04689914
keratinocyte proliferation	GO:0043616		9.882E-05	0.03908261
regulation of cyclin-dependent protein kinase activity	GO:0000079		1.411E-04	0.04784402
positive regulation of B cell proliferation	GO:0030890		1.584E-04	0.04699495
negative regulation of protein kinase activity	GO:0006469		2.252E-04	0.05936863
negative regulation of kinase activity	GO:0033673		2.361E-04	0.05602951
negative regulation of transferase activity	GO:0051348		2.71E-04	0.05846331