pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/6712-8-real-Schmidt-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! skeletal myofibril assembly GO:0014866 7 5 1,000 3,879E-05 0,08922299 ! induction of apoptosis by intracellular signals GO:0008629 67 40 2,000 6,903E-05 0,07938827 ! regulation of protein homodimerization activity GO:0043496 15 7 1,000 8,126E-05 0,06229904 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 1,000 1,082E-04 0,06222068 ! positive regulation of B cell proliferation GO:0030890 11 8 1,000 1,082E-04 0,04977654 ! keratinocyte proliferation GO:0043616 12 8 1,000 1,082E-04 0,04148045 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 2,000 1,433E-04 0,04709397 ! regulation of B cell proliferation GO:0030888 15 10 1,000 1,735E-04 0,04987308 ! negative regulation of protein kinase activity GO:0006469 99 57 2,000 1,997E-04 0,05104324 ! negative regulation of kinase activity GO:0033673 100 58 2,000 2,103E-04 0,04837833 ! negative regulation of transferase activity GO:0051348 105 61 2,000 2,443E-04 0,05108753 ! positive regulation of cell growth GO:0030307 16 12 1,000 2,538E-04 0,04864224 ! regulation of caspase activity GO:0043281 97 65 2,000 2,949E-04 0,05217769 ! regulation of endopeptidase activity GO:0052548 99 67 2,000 3,226E-04 0,05299177 ! negative regulation of caspase activity GO:0043154 20 14 1,000 3,49E-04 0,05351905 ! release of cytochrome c from mitochondria GO:0001836 23 14 1,000 3,49E-04 0,05017411 ! regulation of peptidase activity GO:0052547 106 72 2,000 3,988E-04 0,05395976 ! positive regulation of cell size GO:0045793 20 15 1,000 4,022E-04 0,05139595 ! skin development GO:0043588 25 15 1,000 4,022E-04 0,0486909 ! positive regulation of neuron apoptosis GO:0043525 29 15 1,000 4,022E-04 0,04625636 ! regulation of protein binding GO:0043393 27 16 1,000 4,591E-04 0,05028378 ! negative regulation of peptidase activity GO:0010466 23 17 1,000 5,197E-04 0,05432956 ! apoptotic mitochondrial changes GO:0008637 29 18 1,000 5,839E-04 0,05838987 ! positive regulation of fibroblast proliferation GO:0048146 27 19 1,000 6,518E-04 0,06246157 ! positive regulation of B cell activation GO:0050871 31 20 1,000 7,233E-04 0,06654198 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 1,000 7,984E-04 0,07062887 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 1,000 7,984E-04 0,06801299 ! cellular response to extracellular stimulus GO:0031668 32 21 1,000 7,984E-04 0,06558395 ! regulation of fibroblast proliferation GO:0048145 35 22 1,000 8,772E-04 0,06956721 ! spliceosomal snRNP biogenesis GO:0000387 28 22 1,000 8,772E-04 0,0672483 ! barbed-end actin filament capping GO:0051016 33 22 1,000 8,772E-04 0,065079 GO:0051693|actin filament capping, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 1,000 9,595E-04 0,06896289 ! negative regulation of phosphorylation GO:0042326 41 23 1,000 9,595E-04 0,06687311 ! Ras protein signal transduction GO:0007265 162 100 2,000 1,041E-03 0,07039955 ! insulin receptor signaling pathway GO:0008286 40 24 1,000 1,045E-03 0,06869741 ! negative regulation of actin filament depolymerization GO:0030835 36 25 1,000 1,135E-03 0,07250576 ! negative regulation of actin filament polymerization GO:0030837 36 25 1,000 1,135E-03 0,07054614 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 1,000 1,135E-03 0,06868967 GO:0045936|negative regulation of phosphate metabolic process, ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 1,000 1,228E-03 0,07241475 ! negative regulation of protein polymerization GO:0032272 38 26 1,000 1,228E-03 0,07060438 ! regulation of actin filament depolymerization GO:0030834 39 27 1,000 1,324E-03 0,07429954 ! myofibril assembly GO:0030239 36 27 1,000 1,324E-03 0,0725305 GO:0055002|striated muscle cell development, ! negative regulation of protein complex assembly GO:0031333 42 28 1,000 1,425E-03 0,07619752 ! regulation of B cell activation GO:0050864 42 28 1,000 1,425E-03 0,07446576 ! muscle cell development GO:0055001 38 29 1,000 1,528E-03 0,07810623 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 1,000 1,746E-03 0,08729249 ! actomyosin structure organization GO:0031032 43 33 1,000 1,977E-03 0,09676709 ! negative regulation of hydrolase activity GO:0051346 50 33 1,000 1,977E-03 0,09475111 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 1,000 2,098E-03 0,09849483 ! cellular response to insulin stimulus GO:0032869 52 34 1,000 2,098E-03 0,09652493 ! keratinocyte differentiation GO:0030216 47 35 1,000 2,223E-03 0,10024173 ! positive regulation of leukocyte proliferation GO:0070665 50 35 1,000 2,223E-03 0,098314 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! striated muscle cell differentiation GO:0051146 54 38 1,000 2,616E-03 0,11353947 ! negative regulation of protein complex disassembly GO:0043242 67 39 1,000 2,754E-03 0,11731328 ! regulation of actin filament polymerization GO:0030833 59 40 1,000 2,896E-03 0,1210905 ! epidermal cell differentiation GO:0009913 53 40 1,000 2,896E-03 0,11892816 ! receptor-mediated endocytosis GO:0006898 76 42 1,000 3,188E-03 0,12865227 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 1,000 3,34E-03 0,13243553 ! activation of caspase activity GO:0006919 65 43 1,000 3,34E-03 0,13019086 ! response to insulin stimulus GO:0032868 63 43 1,000 3,34E-03 0,12802101 ! regulation of mast cell proliferation GO:0070666 64 44 1,000 3,494E-03 0,13175336 ! regulation of protein complex disassembly GO:0043244 77 46 1,000 3,814E-03 0,14146877 ! response to UV GO:0009411 75 46 1,000 3,814E-03 0,13922324 ! regulation of leukocyte proliferation GO:0070663 71 47 1,000 3,978E-03 0,14295966 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 77 47 1,000 3,978E-03 0,14076028 ! regulation of protein polymerization GO:0032271 71 47 1,000 3,978E-03 0,13862755 ! positive regulation of caspase activity GO:0043280 72 48 1,000 4,146E-03 0,1423174 GO:0010952|positive regulation of peptidase activity, ! regulation of actin polymerization or depolymerization GO:0008064 68 48 1,000 4,146E-03 0,1402245 ! regulation of actin filament length GO:0030832 72 50 1,000 4,491E-03 0,14970033 ! skeletal muscle fiber development GO:0048741 73 50 1,000 4,491E-03 0,14756175 ! negative regulation of cytoskeleton organization GO:0051494 84 50 1,000 4,491E-03 0,14548341 ! positive regulation of growth GO:0045927 67 50 1,000 4,491E-03 0,14346281 ! muscle fiber development GO:0048747 74 51 1,000 4,668E-03 0,14708866 ! regulation of cellular component size GO:0032535 74 52 1,000 4,849E-03 0,15071617 ! regulation of protein complex assembly GO:0043254 81 54 1,000 5,22E-03 0,1600807 ! DNA damage response, signal transduction GO:0042770 96 56 1,000 5,604E-03 0,1695823 ! response to peptide hormone stimulus GO:0043434 84 57 1,000 5,8E-03 0,17324953 ! actin filament organization GO:0007015 95 59 1,000 6,202E-03 0,1828936 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 1,000 6,617E-03 0,19265512 ! negative regulation of cell growth GO:0030308 106 62 1,000 6,829E-03 0,19634278 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 1,000 6,829E-03 0,19391879 ! negative regulation of cell size GO:0045792 108 64 1,000 7,263E-03 0,20370604 ! regulation of actin cytoskeleton organization GO:0032956 97 64 1,000 7,263E-03 0,20125175 ! neuropeptide signaling pathway GO:0007218 79 64 1,000 7,263E-03 0,1988559 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 1,000 7,484E-03 0,2025017 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 1,000 7,484E-03 0,20014702 ! regulation of actin filament-based process GO:0032970 99 66 1,000 7,708E-03 0,20377429 ! positive regulation of ligase activity GO:0051351 99 69 1,000 8,399E-03 0,21951203 ! muscle cell differentiation GO:0042692 104 71 1,000 8,874E-03 0,22933172 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 1,000 8,874E-03 0,22678359 ! negative regulation of organelle organization GO:0010639 115 72 1,000 9,116E-03 0,23041178 ! mitochondrion organization GO:0007005 104 73 1,000 9,361E-03 0,23403473 ! cellular response to hormone stimulus GO:0032870 109 74 1,000 9,609E-03 0,2376523 ! positive regulation of lymphocyte activation GO:0051251 108 74 1,000 9,609E-03 0,23512408 ! negative regulation of growth GO:0045926 123 75 1,000 9,86E-03 0,23872474 ! regulation of ligase activity GO:0051340 114 75 1,000 9,86E-03 0,23623803 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 9,971E-03 0,23643598 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 9,971E-03 0,23402336 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 9,971E-03 0,23165949 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 9,971E-03 0,2293429 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 9,971E-03 0,22707218 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 9,971E-03 0,22484598 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 9,971E-03 0,22266301 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 9,971E-03 0,22052202 ! sleep GO:0030431 11 5 0,000 9,971E-03 0,21842181 ! negative regulation of bone resorption GO:0045779 10 5 0,000 9,971E-03 0,21636122 ! nucleotide-sugar transport GO:0015780 8 5 0,000 9,971E-03 0,21433916 ! regulation of interferon-beta production GO:0032648 5 5 0,000 9,971E-03 0,21235453 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 9,971E-03 0,21040633 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 9,971E-03 0,20849354 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 9,971E-03 0,20661522 ! tongue development GO:0043586 6 5 0,000 9,971E-03 0,20477044 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 9,971E-03 0,20295832 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 9,971E-03 0,20117798 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 9,971E-03 0,19942861 ! cobalt ion transport GO:0006824 9 5 0,000 9,971E-03 0,19770939 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 9,971E-03 0,19601957 ! SMAD protein complex assembly GO:0007183 9 5 0,000 9,971E-03 0,19435839 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 9,971E-03 0,19272512 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 9,971E-03 0,19111908 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 9,971E-03 0,18953958 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 9,971E-03 0,18798598 ! embryonic camera-type eye development GO:0031076 8 5 0,000 9,971E-03 0,18645764 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 9,971E-03 0,18495395 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 9,971E-03 0,18347432 ! adaptation of signaling pathway GO:0022401 7 5 0,000 9,971E-03 0,18201817 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 9,971E-03 0,18058496 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 9,971E-03 0,17917414 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 9,971E-03 0,17778519 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 9,971E-03 0,17641761 ! positive regulation of histone modification GO:0031058 5 5 0,000 9,971E-03 0,17507091 ! malate metabolic process GO:0006108 7 5 0,000 9,971E-03 0,17374462 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 9,971E-03 0,17243827 ! behavioral response to pain GO:0048266 7 5 0,000 9,971E-03 0,17115142 ! clathrin coat assembly GO:0048268 11 5 0,000 9,971E-03 0,16988363 ! phototransduction, visible light GO:0007603 6 5 0,000 9,971E-03 0,16863448 ! regulation of dopamine uptake GO:0051584 9 5 0,000 9,971E-03 0,16740357 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 9,971E-03 0,16619051 ! mating behavior GO:0007617 6 5 0,000 9,971E-03 0,16499489 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 9,971E-03 0,16381636 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 9,971E-03 0,16265454 ! rhythmic behavior GO:0007622 12 5 0,000 9,971E-03 0,16150908 ! copulation GO:0007620 7 5 0,000 9,971E-03 0,16037965 ! glial cell fate commitment GO:0021781 12 5 0,000 9,971E-03 0,1592659 ! protein maturation by protein folding GO:0022417 12 5 0,000 9,971E-03 0,15816752 ! embryonic hemopoiesis GO:0035162 10 5 0,000 9,971E-03 0,15708418 ! regulation of potassium ion transport GO:0043266 9 5 0,000 9,971E-03 0,15601558 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 9,971E-03 0,15496142 ! apoptotic cell clearance GO:0043277 13 5 0,000 9,971E-03 0,15392141 ! lipoprotein particle clearance GO:0034381 9 5 0,000 9,971E-03 0,15289526 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 9,971E-03 0,15188271 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 9,971E-03 0,15088349 ! response to protozoan GO:0001562 9 5 0,000 9,971E-03 0,14989732 ! positive regulation of glycolysis GO:0045821 11 5 0,000 9,971E-03 0,14892396 ! lymph vessel development GO:0001945 7 5 0,000 9,971E-03 0,14796316 ! endochondral ossification GO:0001958 12 5 0,000 9,971E-03 0,14701468 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 9,971E-03 0,14607828 ! parathyroid gland development GO:0060017 8 5 0,000 9,971E-03 0,14515373 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 9,971E-03 0,14424082 ! anagen GO:0042640 6 5 0,000 9,971E-03 0,14333931 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 9,971E-03 0,142449 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 9,971E-03 0,14156969 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 9,971E-03 0,14070116 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 9,971E-03 0,13984323 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 9,971E-03 0,1389957 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 9,971E-03 0,13815837 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 9,971E-03 0,13733108 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 9,971E-03 0,13651363 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 9,971E-03 0,13570586 ! cardiac muscle fiber development GO:0048739 7 5 0,000 9,971E-03 0,13490759 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 9,971E-03 0,13411865 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 9,971E-03 0,13333889 ! neutrophil mediated immunity GO:0002446 6 5 0,000 9,971E-03 0,13256815 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 9,971E-03 0,13180626 ! ovulation GO:0030728 6 5 0,000 9,971E-03 0,13105308 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 9,971E-03 0,13030846 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 9,971E-03 0,12957226 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 9,971E-03 0,12884432 ! response to pH GO:0009268 9 5 0,000 9,971E-03 0,12812452 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 9,971E-03 0,12741272 ! proline biosynthetic process GO:0006561 6 5 0,000 9,971E-03 0,12670878 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 9,971E-03 0,12601258 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 9,971E-03 0,12532399 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 9,971E-03 0,12464288 ! polyol catabolic process GO:0046174 7 5 0,000 9,971E-03 0,12396913 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 9,971E-03 0,12330263 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 9,971E-03 0,12264326 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 9,971E-03 0,1219909 ! sister chromatid cohesion GO:0007062 9 5 0,000 9,971E-03 0,12134545 ! nerve growth factor processing GO:0032455 7 5 0,000 9,971E-03 0,12070679 ! urea metabolic process GO:0019627 6 5 0,000 9,971E-03 0,12007482 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 9,971E-03 0,11944943 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 9,971E-03 0,11883052 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 9,971E-03 0,11821799 ! neutrophil activation GO:0042119 5 5 0,000 9,971E-03 0,11761174 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 9,971E-03 0,11701168 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 9,971E-03 0,11641771 ! response to food GO:0032094 5 5 0,000 9,971E-03 0,11582975 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 9,971E-03 0,11524769 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 9,971E-03 0,11467145 ! paraxial mesoderm development GO:0048339 9 5 0,000 9,971E-03 0,11410094 ! forebrain neuron development GO:0021884 7 5 0,000 9,971E-03 0,11353609 ! melanosome organization GO:0032438 7 5 0,000 9,971E-03 0,1129768 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 9,971E-03 0,11242299 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 9,971E-03 0,11187458 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 9,971E-03 0,1113315 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 9,971E-03 0,11079367 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 9,971E-03 0,11026101 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 9,971E-03 0,10973344 ! nucleoside transport GO:0015858 6 5 0,000 9,971E-03 0,1092109 ! nucleoside salvage GO:0043174 7 5 0,000 9,971E-03 0,10869332 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 9,971E-03 0,10818061 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 9,971E-03 0,10767272 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 9,971E-03 0,10716958 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 9,971E-03 0,10667112 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 9,971E-03 0,10617727 ! early endosome to late endosome transport GO:0045022 11 5 0,000 9,971E-03 0,10568797 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 9,971E-03 0,10520316 ! depyrimidination GO:0045008 8 5 0,000 9,971E-03 0,10472278 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 9,971E-03 0,10424677 ! 5S class rRNA transcription GO:0042791 8 5 0,000 9,971E-03 0,10377507 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 9,971E-03 0,10330761 ! regulation of centrosome cycle GO:0046605 7 5 0,000 9,971E-03 0,10284435 ! neuronal ion channel clustering GO:0045161 7 5 0,000 9,971E-03 0,10238522 ! sodium ion homeostasis GO:0055078 6 5 0,000 9,971E-03 0,10193018 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 9,971E-03 0,10147916 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 9,971E-03 0,10103211 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 9,971E-03 0,10058899 ! monocyte differentiation GO:0030224 8 5 0,000 9,971E-03 0,10014974 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 9,971E-03 0,0997143 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 9,971E-03 0,09928264 ! centrosome duplication GO:0051298 5 5 0,000 9,971E-03 0,0988547 ! response to UV-C GO:0010225 6 5 0,000 9,971E-03 0,09843043 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 9,971E-03 0,09800979 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 9,971E-03 0,09759272 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 9,971E-03 0,09717919 ! regulation of dendrite development GO:0050773 12 5 0,000 9,971E-03 0,09676916 ! peptidyl-arginine modification GO:0018195 7 5 0,000 9,971E-03 0,09636256 ! positive regulation of organ growth GO:0046622 6 5 0,000 9,971E-03 0,09595937 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 9,971E-03 0,09555954 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 9,971E-03 0,09516303 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 9,971E-03 0,09476979 ! regulation of dopamine secretion GO:0014059 12 5 0,000 9,971E-03 0,09437979 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 9,971E-03 0,09399299 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 9,971E-03 0,09360935 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 9,971E-03 0,09322882 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 9,971E-03 0,09285138 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 9,971E-03 0,09247697 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 9,971E-03 0,09210558 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 9,971E-03 0,09173716 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 9,971E-03 0,09137167 ! neural tube patterning GO:0021532 6 5 0,000 9,971E-03 0,09100909 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 9,971E-03 0,09064937 ! histone demethylation GO:0016577 9 5 0,000 9,971E-03 0,09029248 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 9,971E-03 0,08993839 ! regulation of sterol transport GO:0032371 7 5 0,000 9,971E-03 0,08958707 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 9,971E-03 0,08923848 ! enteric nervous system development GO:0048484 8 5 0,000 9,971E-03 0,0888926 ! establishment of planar polarity GO:0001736 6 5 0,000 9,971E-03 0,08854938 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 9,971E-03 0,08820881 ! muscle cell proliferation GO:0033002 8 5 0,000 9,971E-03 0,08787084 ! transcription termination GO:0006353 8 5 0,000 9,971E-03 0,08753546 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 9,971E-03 0,08720262 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 9,971E-03 0,08687231 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 9,971E-03 0,08654449 ! regulation of respiratory burst GO:0060263 8 5 0,000 9,971E-03 0,08621913 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 9,971E-03 0,08589622 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 9,971E-03 0,08557571 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 9,971E-03 0,08525758 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 9,971E-03 0,08494181 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 9,971E-03 0,08462838 ! apical protein localization GO:0045176 6 5 0,000 9,971E-03 0,08431724 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 9,971E-03 0,08400839 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 9,971E-03 0,08370179 ! galactolipid metabolic process GO:0019374 7 5 0,000 9,971E-03 0,08339742 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 9,971E-03 0,08309525 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 9,971E-03 0,08279527 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 9,971E-03 0,08249745 ! triglyceride catabolic process GO:0019433 6 5 0,000 9,971E-03 0,08220176 ! glial cell migration GO:0008347 10 5 0,000 9,971E-03 0,08190818 ! determination of adult lifespan GO:0008340 8 5 0,000 9,971E-03 0,08161669 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 9,971E-03 0,08132727 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 9,971E-03 0,08103989 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 9,971E-03 0,08075454 ! somatic stem cell maintenance GO:0035019 13 5 0,000 9,971E-03 0,08047119 ! cerebellar cortex formation GO:0021697 6 5 0,000 9,971E-03 0,08018982 ! neural plate development GO:0001840 6 5 0,000 9,971E-03 0,07991042 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 9,971E-03 0,07963295 ! regulation of sensory perception GO:0051931 6 5 0,000 9,971E-03 0,0793574 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 9,971E-03 0,07908376 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 9,971E-03 0,07881199 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 9,971E-03 0,07854209 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 9,971E-03 0,07827403 ! sensory cilium assembly GO:0035058 6 5 0,000 9,971E-03 0,07800779 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 9,971E-03 0,07774336 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 9,971E-03 0,07748071 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 9,971E-03 0,07721983 ! spindle assembly GO:0051225 5 5 0,000 9,971E-03 0,0769607 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 9,971E-03 0,07670331 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 9,971E-03 0,07644763 ! protein amino acid prenylation GO:0018346 9 5 0,000 9,971E-03 0,07619365 ! organ regeneration GO:0031100 7 5 0,000 9,971E-03 0,07594136 ! NAD biosynthetic process GO:0009435 7 5 0,000 9,971E-03 0,07569073 ! carnitine metabolic process GO:0009437 5 5 0,000 9,971E-03 0,07544174 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 9,971E-03 0,07519439 ! cellular anion homeostasis GO:0030002 6 5 0,000 9,971E-03 0,07494866 GO:0055081|anion homeostasis, ! cellular respiration GO:0045333 107 79 1,000 0,01089314 0,08160988 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 1,000 0,01115852 0,08332662 GO:0010498|proteasomal protein catabolic process, ! positive regulation of cell activation GO:0050867 120 81 1,000 0,01142675 0,08505346 GO:0002696|positive regulation of leukocyte activation, ! tRNA transcription GO:0009304 11 6 0,000 0,01195409 0,08869166 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,01195409 0,08840648 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,01195409 0,08812312 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,01195409 0,08784158 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01195409 0,08756183 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,01195409 0,08728386 ! regulation of helicase activity GO:0051095 11 6 0,000 0,01195409 0,08700764 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,01195409 0,08673317 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,01195409 0,08646042 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,01195409 0,08618939 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,01195409 0,08592005 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,01195409 0,08565238 ! prostate gland development GO:0030850 9 6 0,000 0,01195409 0,08538638 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,01195409 0,08512203 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,01195409 0,0848593 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,01195409 0,0845982 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,01195409 0,08433869 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,01195409 0,08408078 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,01195409 0,08382443 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,01195409 0,08356965 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,01195409 0,08331641 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,01195409 0,0830647 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 0,01195409 0,0828145 ! neuron adhesion GO:0007158 9 6 0,000 0,01195409 0,08256581 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 0,01195409 0,08231861 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,01195409 0,08207288 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,01195409 0,08182861 ! signal peptide processing GO:0006465 8 6 0,000 0,01195409 0,0815858 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,01195409 0,08134442 ! mRNA stabilization GO:0048255 15 6 0,000 0,01195409 0,08110447 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,01195409 0,08086592 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,01195409 0,08062878 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,01195409 0,08039302 ! opsonization GO:0008228 8 6 0,000 0,01195409 0,08015864 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,01195409 0,07992562 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,01195409 0,07969395 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,01195409 0,07946363 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,01195409 0,07923462 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,01195409 0,07900694 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01195409 0,07878056 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,01195409 0,07855547 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,01195409 0,07833167 ! mechanosensory behavior GO:0007638 8 6 0,000 0,01195409 0,07810913 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,01195409 0,07788786 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,01195409 0,07766784 ! response to interferon-gamma GO:0034341 12 6 0,000 0,01195409 0,07744905 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,01195409 0,0772315 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,01195409 0,07701517 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01195409 0,07680004 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,01195409 0,07658611 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,01195409 0,07637337 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,01195409 0,07616181 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,01195409 0,07595142 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,01195409 0,07574219 ! thymic T cell selection GO:0045061 12 6 0,000 0,01195409 0,07553411 ! protein lipoylation GO:0009249 10 6 0,000 0,01195409 0,07532716 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,01195409 0,07512135 ! pigment granule organization GO:0048753 11 6 0,000 0,01195409 0,07491666 ! drug transport GO:0015893 6 6 0,000 0,01195409 0,07471308 ! cysteine metabolic process GO:0006534 7 6 0,000 0,01195409 0,07451061 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,01195409 0,07430923 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,01195409 0,07410893 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01195409 0,07390972 ! histidine metabolic process GO:0006547 6 6 0,000 0,01195409 0,07371157 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,01195409 0,07351448 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,01195409 0,07331844 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,01195409 0,07312344 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,01195409 0,07292948 ! adenohypophysis development GO:0021984 10 6 0,000 0,01195409 0,07273655 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,01195409 0,07254463 ! hyperosmotic response GO:0006972 8 6 0,000 0,01195409 0,07235372 ! microtubule nucleation GO:0007020 10 6 0,000 0,01195409 0,07216382 ! ER overload response GO:0006983 7 6 0,000 0,01195409 0,07197491 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,01195409 0,07178698 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,01195409 0,07160004 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,01195409 0,07141406 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,01195409 0,07122905 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,01195409 0,071045 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,01195409 0,07086189 ! response to dietary excess GO:0002021 7 6 0,000 0,01195409 0,07067973 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,01195409 0,0704985 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,01195409 0,0703182 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,01195409 0,07013881 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,01195409 0,06996034 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,01195409 0,06978278 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,01195409 0,06960611 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01195409 0,06943034 ! neuron apoptosis GO:0051402 8 6 0,000 0,01195409 0,06925545 ! organic alcohol transport GO:0015850 9 6 0,000 0,01195409 0,06908144 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,01195409 0,06890831 ! T cell mediated immunity GO:0002456 12 6 0,000 0,01195409 0,06873604 ! male sex determination GO:0030238 9 6 0,000 0,01195409 0,06856462 ! carnitine transport GO:0015879 8 6 0,000 0,01195409 0,06839407 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,01195409 0,06822435 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,01195409 0,06805548 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01195409 0,06788744 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,01195409 0,06772023 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,01195409 0,06755384 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,01195409 0,06738827 ! parturition GO:0007567 12 6 0,000 0,01195409 0,06722351 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,01195409 0,06705955 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,01195409 0,06689639 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,01195409 0,06673402 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,01195409 0,06657243 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,01195409 0,06641163 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,01195409 0,0662516 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,01195409 0,06609234 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,01195409 0,06593385 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,01195409 0,06577611 ! macrophage differentiation GO:0030225 10 6 0,000 0,01195409 0,06561913 ! astrocyte development GO:0014002 14 6 0,000 0,01195409 0,06546289 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,01195409 0,0653074 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,01195409 0,06515264 ! interaction with symbiont GO:0051702 8 6 0,000 0,01195409 0,06499862 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,01195409 0,06484532 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01195409 0,06469274 ! eating behavior GO:0042755 6 6 0,000 0,01195409 0,06454088 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,01195409 0,06438973 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,01195409 0,06423929 ! response to copper ion GO:0046688 9 6 0,000 0,01195409 0,06408954 ! DNA topological change GO:0006265 8 6 0,000 0,01195409 0,0639405 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,01195409 0,06379214 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,01195409 0,06364448 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,01195409 0,06349749 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01195409 0,06335119 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01195409 0,06320555 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,01195409 0,06306058 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,01195409 0,06291628 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,01195409 0,06277264 ! gas homeostasis GO:0033483 11 6 0,000 0,01195409 0,06262965 ! hair follicle maturation GO:0048820 7 6 0,000 0,01195409 0,06248731 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,01195409 0,06234561 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,01195409 0,06220456 ! Schwann cell development GO:0014044 14 6 0,000 0,01195409 0,06206414 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,01195409 0,06192436 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,01195409 0,0617852 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01195409 0,06164667 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,01195409 0,06150876 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,01195409 0,06137146 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,01195409 0,06123478 ! histone ubiquitination GO:0016574 7 6 0,000 0,01195409 0,0610987 ! regulation of meiosis GO:0040020 10 6 0,000 0,01195409 0,06096322 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,01195409 0,06082835 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,01195409 0,06069407 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,01195409 0,06056038 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,01195409 0,06042728 ! membrane to membrane docking GO:0022614 12 6 0,000 0,01195409 0,06029477 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,01195409 0,06016283 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,01195409 0,06003147 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,01195409 0,05990069 ! receptor internalization GO:0031623 9 6 0,000 0,01195409 0,05977047 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,01195409 0,05964081 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,01195409 0,05951172 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01195409 0,05938318 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,01195409 0,0592552 ! protein deubiquitination GO:0016579 8 6 0,000 0,01195409 0,05912777 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,01195409 0,05900089 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,01195409 0,05887455 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,01195409 0,05874875 ! axonal fasciculation GO:0007413 9 6 0,000 0,01195409 0,05862349 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,01195409 0,05849875 ! thiamin metabolic process GO:0006772 6 6 0,000 0,01195409 0,05837455 ! midbrain development GO:0030901 6 6 0,000 0,01195409 0,05825088 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,01195409 0,05812773 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01195409 0,05800509 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,01195409 0,05788298 ! progesterone metabolic process GO:0042448 8 6 0,000 0,01195409 0,05776137 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,01195409 0,05764028 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,01195409 0,0575197 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,01195409 0,05739961 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,01195409 0,05728003 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,01195409 0,05716094 ! adult feeding behavior GO:0008343 6 6 0,000 0,01195409 0,05704235 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,01195409 0,05692425 ! blastocyst growth GO:0001832 15 6 0,000 0,01195409 0,05680664 ! pigment granule transport GO:0051904 12 6 0,000 0,01195409 0,05668951 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,01195409 0,05657287 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,01195409 0,0564567 ! catecholamine transport GO:0051937 7 6 0,000 0,01195409 0,05634101 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01195409 0,0562258 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,01195409 0,05611105 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,01195409 0,05599677 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,01195409 0,05588296 ! protein prenylation GO:0018342 10 6 0,000 0,01195409 0,0557696 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01195409 0,05565671 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,01195409 0,05554427 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,01195409 0,05543229 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,01195409 0,05532075 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,01195409 0,05520967 ! cell cycle arrest GO:0007050 150 86 1,000 0,01281021 0,05904507 ! interphase of mitotic cell cycle GO:0051329 156 86 1,000 0,01281021 0,05892698 ! skeletal muscle tissue development GO:0007519 123 87 1,000 0,01309529 0,0601181 GO:0060538|skeletal muscle organ development, ! interphase GO:0051325 159 88 1,000 0,01338314 0,06131715 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 0,000 0,0139329 0,06370908 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,0139329 0,06358267 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,0139329 0,06345677 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,0139329 0,06333136 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,0139329 0,06320644 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,0139329 0,06308202 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,0139329 0,06295809 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,0139329 0,06283464 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,0139329 0,06271168 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,0139329 0,06258919 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,0139329 0,06246719 ! reproductive behavior GO:0019098 12 7 0,000 0,0139329 0,06234566 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,0139329 0,0622246 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,0139329 0,06210401 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,0139329 0,06198388 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,0139329 0,06186422 ! oligopeptide transport GO:0006857 11 7 0,000 0,0139329 0,06174502 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,0139329 0,06162628 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,0139329 0,061508 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,0139329 0,06139017 ! RNA methylation GO:0001510 11 7 0,000 0,0139329 0,06127279 ! pericardium development GO:0060039 8 7 0,000 0,0139329 0,06115585 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,0139329 0,06103937 ! fibril organization GO:0043206 13 7 0,000 0,0139329 0,06092332 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,0139329 0,06080772 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,0139329 0,06069255 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,0139329 0,06057782 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,0139329 0,06046352 ! lipoprotein transport GO:0042953 9 7 0,000 0,0139329 0,06034966 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,0139329 0,06023622 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,0139329 0,0601232 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,0139329 0,06001061 ! estrogen metabolic process GO:0008210 14 7 0,000 0,0139329 0,05989844 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,0139329 0,05978669 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,0139329 0,05967536 ! chemosensory behavior GO:0007635 9 7 0,000 0,0139329 0,05956444 ! microtubule bundle formation GO:0001578 8 7 0,000 0,0139329 0,05945393 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,0139329 0,05934383 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,0139329 0,05923414 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,0139329 0,05912485 ! leukocyte degranulation GO:0043299 10 7 0,000 0,0139329 0,05901596 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,0139329 0,05890748 ! reflex GO:0060004 12 7 0,000 0,0139329 0,05879939 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,0139329 0,0586917 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,0139329 0,0585844 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,0139329 0,0584775 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,0139329 0,05837098 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,0139329 0,05826485 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,0139329 0,05815911 ! spinal cord patterning GO:0021511 7 7 0,000 0,0139329 0,05805375 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,0139329 0,05794877 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,0139329 0,05784416 ! adrenal gland development GO:0030325 17 7 0,000 0,0139329 0,05773994 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,0139329 0,05763609 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,0139329 0,05753262 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,0139329 0,05742951 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,0139329 0,05732678 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,0139329 0,05722441 ! endosome organization GO:0007032 10 7 0,000 0,0139329 0,0571224 ! thyroid hormone generation GO:0006590 11 7 0,000 0,0139329 0,05702076 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,0139329 0,05691948 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,0139329 0,05681856 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,0139329 0,056718 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,0139329 0,05661779 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,0139329 0,05651793 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,0139329 0,05641843 ! galactose metabolic process GO:0006012 10 7 0,000 0,0139329 0,05631927 ! vesicle fusion GO:0006906 15 7 0,000 0,0139329 0,05622047 ! intracellular pH reduction GO:0051452 10 7 0,000 0,0139329 0,05612201 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,0139329 0,05602389 ! organ growth GO:0035265 11 7 0,000 0,0139329 0,05592612 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,0139329 0,05582869 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,0139329 0,0557316 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,0139329 0,05563484 ! retinol metabolic process GO:0042572 9 7 0,000 0,0139329 0,05553842 ! behavioral fear response GO:0001662 13 7 0,000 0,0139329 0,05544233 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,0139329 0,05534658 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,0139329 0,05525115 ! rRNA modification GO:0000154 12 7 0,000 0,0139329 0,05515605 ! protein heterooligomerization GO:0051291 10 7 0,000 0,0139329 0,05506128 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,0139329 0,05496684 ! response to UV-B GO:0010224 11 7 0,000 0,0139329 0,05487272 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,0139329 0,05477892 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,0139329 0,05468544 ! intermediate filament organization GO:0045109 11 7 0,000 0,0139329 0,05459228 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,0139329 0,05449943 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,0139329 0,05440691 ! fibrinolysis GO:0042730 9 7 0,000 0,0139329 0,05431469 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,0139329 0,05422279 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,0139329 0,05413119 ! B cell lineage commitment GO:0002326 17 7 0,000 0,0139329 0,05403991 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,0139329 0,05394893 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,0139329 0,05385826 ! response to tropane GO:0014073 13 7 0,000 0,0139329 0,0537679 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,0139329 0,05367783 ! melanosome localization GO:0032400 10 7 0,000 0,0139329 0,05358807 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,0139329 0,05349861 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,0139329 0,05340945 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,0139329 0,05332058 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,0139329 0,05323201 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,0139329 0,05314373 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,0139329 0,05305574 ! mast cell activation GO:0045576 9 7 0,000 0,0139329 0,05296805 ! multicellular organismal aging GO:0010259 11 7 0,000 0,0139329 0,05288064 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,0139329 0,05279352 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,0139329 0,05270669 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,0139329 0,05262014 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,0139329 0,05253388 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,0139329 0,0524479 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,0139329 0,0523622 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,0139329 0,05227678 ! T cell lineage commitment GO:0002360 12 7 0,000 0,0139329 0,05219164 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,0139329 0,05210678 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,0139329 0,05202219 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,0139329 0,05193787 ! regulation of lipid transport GO:0032368 13 7 0,000 0,0139329 0,05185383 ! response to tumor cell GO:0002347 12 7 0,000 0,0139329 0,05177006 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,0139329 0,05168656 ! neuroblast proliferation GO:0007405 13 7 0,000 0,0139329 0,05160333 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,0139329 0,05152037 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,0139329 0,05143767 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,0139329 0,05135524 ! diuresis GO:0030146 12 7 0,000 0,0139329 0,05127307 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,0139329 0,05119116 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,0139329 0,05110952 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,0139329 0,05102813 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,0139329 0,05094701 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,0139329 0,05086614 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,0139329 0,05078553 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,0139329 0,05070517 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,0139329 0,05062507 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,0139329 0,05054522 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,0139329 0,05046562 ! lymph node development GO:0048535 9 7 0,000 0,0139329 0,05038627 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,0139329 0,05030717 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,0139329 0,05022832 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,0139329 0,05014971 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,0139329 0,05007136 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,0139329 0,04999324 ! ATP catabolic process GO:0006200 10 7 0,000 0,0139329 0,04991537 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,0139329 0,04983774 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,0139329 0,04976035 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,0139329 0,04968321 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,0139329 0,0496063 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,0139329 0,04952962 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,0139329 0,04945319 ! muscle adaptation GO:0043500 12 7 0,000 0,0139329 0,04937699 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,0139329 0,04930103 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,0139329 0,0492253 ! retina homeostasis GO:0001895 9 7 0,000 0,0139329 0,0491498 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,0139329 0,04907453 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,0139329 0,04899949 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,0139329 0,04892468 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,0139329 0,0488501 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,0139329 0,04877575 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,0139329 0,04870162 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,0139329 0,04862772 ! regulation of cytoskeleton organization GO:0051493 154 93 1,000 0,01486347 0,05179696 ! regulation of binding GO:0051098 151 95 1,000 0,01547458 0,05384499 ! regulation of cellular component biogenesis GO:0044087 158 96 1,000 0,01578416 0,05483921 ! response to light stimulus GO:0009416 153 96 1,000 0,01578416 0,0547565 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,01590785 0,05510251 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,01590785 0,05501965 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 11 8 0,000 0,01590785 0,05493703 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,01590785 0,05485467 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,01590785 0,05477255 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,01590785 0,05469068 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,01590785 0,05460905 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,01590785 0,05452767 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,01590785 0,05444653 ! phosphate transport GO:0006817 10 8 0,000 0,01590785 0,05436562 ! N-glycan processing GO:0006491 12 8 0,000 0,01590785 0,05428496 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,01590785 0,05420454 ! UTP metabolic process GO:0046051 8 8 0,000 0,01590785 0,05412436 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,01590785 0,05404441 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,01590785 0,0539647 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,01590785 0,05388522 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,01590785 0,05380598 ! succinate metabolic process GO:0006105 14 8 0,000 0,01590785 0,05372697 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,01590785 0,05364819 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,01590785 0,05356964 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01590785 0,05349132 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,01590785 0,05341323 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,01590785 0,05333537 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,01590785 0,05325774 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,01590785 0,05318033 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01590785 0,05310314 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,01590785 0,05302618 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,01590785 0,05294944 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,01590785 0,05287293 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,01590785 0,05279663 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,01590785 0,05272055 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,01590785 0,0526447 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,01590785 0,05256906 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,01590785 0,05249364 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 0,000 0,01590785 0,05241843 ! astrocyte differentiation GO:0048708 16 8 0,000 0,01590785 0,05234344 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,01590785 0,05226866 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,01590785 0,0521941 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,01590785 0,05211975 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,01590785 0,05204561 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,01590785 0,05197168 ! melanin metabolic process GO:0006582 12 8 0,000 0,01590785 0,05189796 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,01590785 0,05182445 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01590785 0,05175115 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,01590785 0,05167806 ! macrophage activation GO:0042116 12 8 0,000 0,01590785 0,05160517 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,01590785 0,05153249 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,01590785 0,05146001 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,01590785 0,05138773 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,01590785 0,05131566 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01590785 0,05124379 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,01590785 0,05117212 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,01590785 0,05110065 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,01590785 0,05102938 ! ruffle organization GO:0031529 11 8 0,000 0,01590785 0,05095831 ! osteoblast development GO:0002076 13 8 0,000 0,01590785 0,05088743 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,01590785 0,05081676 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,01590785 0,05074628 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,01590785 0,05067599 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,01590785 0,0506059 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,01590785 0,050536 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,01590785 0,0504663 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,01590785 0,05039678 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,01590785 0,05032746 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,01590785 0,05025833 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,01590785 0,05018939 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,01590785 0,05012064 ! oligodendrocyte development GO:0014003 8 8 0,000 0,01590785 0,05005207 ! segment specification GO:0007379 10 8 0,000 0,01590785 0,0499837 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,01590785 0,0499155 ! cellular extravasation GO:0045123 11 8 0,000 0,01590785 0,0498475 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,01590785 0,04977968 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,01590785 0,04971205 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,01590785 0,04964459 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,01590785 0,04957732 ! snRNA metabolic process GO:0016073 10 8 0,000 0,01590785 0,04951024 GO:0016180|snRNA processing, ! phosphoinositide 3-kinase cascade GO:0014065 23 8 0,000 0,01590785 0,04944333 ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,01590785 0,04937661 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,01590785 0,04931006 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,01590785 0,04924369 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,01590785 0,04917751 ! nucleosome disassembly GO:0006337 12 8 0,000 0,01590785 0,0491115 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,01590785 0,04904566 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,01590785 0,04898001 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,01590785 0,04891453 ! icosanoid secretion GO:0032309 12 8 0,000 0,01590785 0,04884922 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,01590785 0,04878409 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01590785 0,04871913 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,01590785 0,04865434 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,01590785 0,04858973 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,01590785 0,04852529 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,01590785 0,04846101 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,01590785 0,04839691 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,01590785 0,04833298 ! sterol catabolic process GO:0016127 9 8 0,000 0,01590785 0,04826922 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,01590785 0,04820562 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,01590785 0,04814219 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,01590785 0,04807893 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,01590785 0,04801583 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01590785 0,0479529 ! prophase GO:0051324 11 8 0,000 0,01590785 0,04789014 ! S phase GO:0051320 8 8 0,000 0,01590785 0,04782754 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,01590785 0,0477651 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,01590785 0,04770282 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,01590785 0,04764071 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,01590785 0,04757876 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,01590785 0,04751697 ! hormone catabolic process GO:0042447 13 8 0,000 0,01590785 0,04745534 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,01590785 0,04739387 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,01590785 0,04733256 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,01590785 0,0472714 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,01590785 0,04721041 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,01590785 0,04714957 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,01590785 0,04708889 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,01590785 0,04702836 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01590785 0,04696799 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,01590785 0,04690778 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,01590785 0,04684771 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,01590785 0,04678781 ! lamellipodium assembly GO:0030032 9 8 0,000 0,01590785 0,04672805 ! regulation of embryonic development GO:0045995 16 8 0,000 0,01590785 0,04666845 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01590785 0,046609 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,01590785 0,0465497 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,01590785 0,04649055 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 1,000 0,01672882 0,04882778 ! homophilic cell adhesion GO:0007156 149 100 1,000 0,01704899 0,0496992 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,01787897 0,05205269 ! regulation of developmental growth GO:0048638 13 9 0,000 0,01787897 0,05198688 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,01787897 0,05192124 ! telencephalon cell migration GO:0022029 16 9 0,000 0,01787897 0,05185577 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,01787897 0,05179046 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,01787897 0,05172531 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,01787897 0,05166033 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,01787897 0,05159551 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,01787897 0,05153086 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,01787897 0,05146636 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,01787897 0,05140203 ! GTP metabolic process GO:0046039 9 9 0,000 0,01787897 0,05133786 ! elastic fiber assembly GO:0048251 13 9 0,000 0,01787897 0,05127385 ! social behavior GO:0035176 14 9 0,000 0,01787897 0,05120999 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,01787897 0,0511463 ! artery development GO:0060840 19 9 0,000 0,01787897 0,05108276 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,01787897 0,05101939 ! regulation of glycolysis GO:0006110 15 9 0,000 0,01787897 0,05095616 ! response to pain GO:0048265 16 9 0,000 0,01787897 0,0508931 ! protein complex disassembly GO:0043241 17 9 0,000 0,01787897 0,05083019 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,01787897 0,05076744 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,01787897 0,05070484 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,01787897 0,05064239 ! lung alveolus development GO:0048286 17 9 0,000 0,01787897 0,0505801 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,01787897 0,05051797 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,01787897 0,05045598 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,01787897 0,05039415 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,01787897 0,05033247 ! ventral spinal cord development GO:0021517 11 9 0,000 0,01787897 0,05027093 ! protein targeting to ER GO:0045047 19 9 0,000 0,01787897 0,05020955 ! T cell selection GO:0045058 18 9 0,000 0,01787897 0,05014832 ! endoderm development GO:0007492 12 9 0,000 0,01787897 0,05008724 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,01787897 0,05002631 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,01787897 0,04996552 ! arginine catabolic process GO:0006527 10 9 0,000 0,01787897 0,04990488 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,01787897 0,04984439 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,01787897 0,04978405 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,01787897 0,04972385 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01787897 0,0496638 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,01787897 0,04960389 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,01787897 0,04954413 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,01787897 0,04948451 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,01787897 0,04942503 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01787897 0,0493657 ! mannose metabolic process GO:0006013 9 9 0,000 0,01787897 0,0493065 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,01787897 0,04924745 ! receptor clustering GO:0043113 15 9 0,000 0,01787897 0,04918855 ! epithelial cell development GO:0002064 10 9 0,000 0,01787897 0,04912978 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,01787897 0,04907115 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,01787897 0,04901266 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,01787897 0,04895432 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,01787897 0,04889611 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,01787897 0,04883803 ! motor axon guidance GO:0008045 14 9 0,000 0,01787897 0,0487801 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,01787897 0,0487223 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,01787897 0,04866464 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,01787897 0,04860712 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,01787897 0,04854973 ! blastoderm segmentation GO:0007350 11 9 0,000 0,01787897 0,04849248 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,01787897 0,04843536 ! DNA ligation GO:0006266 14 9 0,000 0,01787897 0,04837838 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,01787897 0,04832153 ! response to amine stimulus GO:0014075 13 9 0,000 0,01787897 0,04826482 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,01787897 0,04820824 ! erythrocyte development GO:0048821 11 9 0,000 0,01787897 0,04815179 ! renal water homeostasis GO:0003091 14 9 0,000 0,01787897 0,04809547 ! postreplication repair GO:0006301 11 9 0,000 0,01787897 0,04803928 ! mRNA cleavage GO:0006379 13 9 0,000 0,01787897 0,04798323 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,01787897 0,0479273 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,01787897 0,04787151 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,01787897 0,04781584 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,01787897 0,04776031 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,01787897 0,0477049 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,01787897 0,04764962 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,01787897 0,04759447 ! acid secretion GO:0046717 14 9 0,000 0,01787897 0,04753945 ! musculoskeletal movement GO:0050881 11 9 0,000 0,01787897 0,04748455 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,01787897 0,04742979 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,01787897 0,04737514 ! purine base metabolic process GO:0006144 18 9 0,000 0,01787897 0,04732063 ! oocyte differentiation GO:0009994 12 9 0,000 0,01787897 0,04726624 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,01787897 0,04721197 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,01787897 0,04715783 ! spleen development GO:0048536 15 9 0,000 0,01787897 0,04710381 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,01787897 0,04704991 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,01787897 0,04699614 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,01787897 0,04694249 ! detection of calcium ion GO:0005513 13 9 0,000 0,01787897 0,04688897 ! blastocyst formation GO:0001825 12 9 0,000 0,01787897 0,04683556 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,01787897 0,04678228 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,01787897 0,04672912 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,01787897 0,04667608 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,01787897 0,04662316 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01787897 0,04657036 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,01787897 0,04651767 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,01787897 0,04646511 ! prepulse inhibition GO:0060134 14 9 0,000 0,01787897 0,04641267 ! embryonic placenta development GO:0001892 12 9 0,000 0,01787897 0,04636034 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,01787897 0,04630814 ! insulin secretion GO:0030073 17 9 0,000 0,01787897 0,04625605 ! sequestering of metal ion GO:0051238 11 9 0,000 0,01787897 0,04620407 ! response to nicotine GO:0035094 16 9 0,000 0,01787897 0,04615222 ! establishment of cell polarity GO:0030010 12 9 0,000 0,01787897 0,04610048 ! nucleus localization GO:0051647 15 9 0,000 0,01787897 0,04604885 ! regulation of synapse organization GO:0050807 12 9 0,000 0,01787897 0,04599734 ! localization within membrane GO:0051668 15 9 0,000 0,01787897 0,04594595 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,01984624 0,0509446 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,01984624 0,05088781 ! neuron fate specification GO:0048665 11 10 0,000 0,01984624 0,05083114 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,01984624 0,0507746 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,01984624 0,05071818 ! thyroid gland development GO:0030878 19 10 0,000 0,01984624 0,05066189 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,01984624 0,05060572 ! synapsis GO:0007129 13 10 0,000 0,01984624 0,05054968 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,01984624 0,05049376 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,01984624 0,05043797 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,01984624 0,0503823 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,01984624 0,05032675 ! sulfate transport GO:0008272 12 10 0,000 0,01984624 0,05027132 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,01984624 0,05021602 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,01984624 0,05016084 ! androgen metabolic process GO:0008209 13 10 0,000 0,01984624 0,05010578 ! phospholipid efflux GO:0033700 16 10 0,000 0,01984624 0,05005084 ! hippocampus development GO:0021766 19 10 0,000 0,01984624 0,04999602 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,01984624 0,04994132 ! blood vessel remodeling GO:0001974 21 10 0,000 0,01984624 0,04988673 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,01984624 0,04983227 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,01984624 0,04977793 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,01984624 0,04972371 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,01984624 0,0496696 ! pathogenesis GO:0009405 13 10 0,000 0,01984624 0,04961561 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,01984624 0,04956174 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01984624 0,04950799 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,01984624 0,04945435 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 0,01984624 0,04940083 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,01984624 0,04934742 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,01984624 0,04929413 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,01984624 0,04924095 ! melanocyte differentiation GO:0030318 15 10 0,000 0,01984624 0,04918789 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,01984624 0,04913494 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,01984624 0,04908211 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,01984624 0,04902939 ! response to X-ray GO:0010165 16 10 0,000 0,01984624 0,04897678 ! B cell proliferation GO:0042100 14 10 0,000 0,01984624 0,04892429 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,01984624 0,04887191 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,01984624 0,04881964 ! forebrain cell migration GO:0021885 17 10 0,000 0,01984624 0,04876748 ! lipid digestion GO:0044241 15 10 0,000 0,01984624 0,04871543 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,01984624 0,0486635 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,01984624 0,04861167 ! UV protection GO:0009650 14 10 0,000 0,01984624 0,04855996 ! entry into host cell GO:0030260 20 10 0,000 0,01984624 0,04850836 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,01984624 0,04845686 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,01984624 0,04840547 ! negative regulation of ossification GO:0030279 19 10 0,000 0,01984624 0,0483542 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,01984624 0,04830303 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,01984624 0,04825197 ! regulation of bone resorption GO:0045124 24 10 0,000 0,01984624 0,04820102 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,01984624 0,04815017 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,01984624 0,04809943 ! regulation of organ growth GO:0046620 11 10 0,000 0,01984624 0,0480488 ! response to dsRNA GO:0043331 18 10 0,000 0,01984624 0,04799828 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,01984624 0,04794786 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,01984624 0,04789755 ! embryonic axis specification GO:0000578 12 10 0,000 0,01984624 0,04784734 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,01984624 0,04779724 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,01984624 0,04774724 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,01984624 0,04769735 ! cranial nerve development GO:0021545 12 10 0,000 0,01984624 0,04764756 ! fucose catabolic process GO:0019317 16 10 0,000 0,01984624 0,04759788 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,01984624 0,04754829 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,01984624 0,04749882 ! protein sumoylation GO:0016925 12 10 0,000 0,01984624 0,04744944 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,01984624 0,04740017 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01984624 0,047351 ! zymogen activation GO:0031638 14 10 0,000 0,01984624 0,04730193 ! salivary gland development GO:0007431 22 10 0,000 0,01984624 0,04725296 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,01984624 0,0472041 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,01984624 0,04715533 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,01984624 0,04710667 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,01984624 0,04705811 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,01984624 0,04700964 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,01984624 0,04696128 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,01984624 0,04691301 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,01984624 0,04686485 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,01984624 0,04681678 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,01984624 0,04676881 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,01984624 0,04672094 ! detection of bacterium GO:0016045 10 10 0,000 0,01984624 0,04667317 ! embryonic gut development GO:0048566 11 10 0,000 0,01984624 0,0466255 ! activation of innate immune response GO:0002218 10 10 0,000 0,01984624 0,04657792 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,01984624 0,04653044 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,01984624 0,04648306 ! developmental induction GO:0031128 13 10 0,000 0,01984624 0,04643577 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,01984624 0,04638858 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,01984624 0,04634148 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,01984624 0,04629449 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,01984624 0,04624758 ! rRNA transcription GO:0009303 17 11 0,000 0,02180969 0,05077155 ! respiratory burst GO:0045730 14 11 0,000 0,02180969 0,05072022 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,02180969 0,05066898 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,02180969 0,05061786 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,02180969 0,05056683 ! virus-host interaction GO:0019048 17 11 0,000 0,02180969 0,05051591 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 0,02180969 0,05046509 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,02180969 0,05041437 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,02180969 0,05036375 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,02180969 0,05031323 ! RNA polyadenylation GO:0043631 19 11 0,000 0,02180969 0,05026282 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,02180969 0,05021251 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,02180969 0,0501623 ! mating GO:0007618 14 11 0,000 0,02180969 0,05011218 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,02180969 0,05006217 ! T cell proliferation GO:0042098 20 11 0,000 0,02180969 0,05001226 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,02180969 0,04996245 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,02180969 0,04991273 ! bone resorption GO:0045453 16 11 0,000 0,02180969 0,04986312 ! regulated secretory pathway GO:0045055 14 11 0,000 0,02180969 0,0498136 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,02180969 0,04976418 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,02180969 0,04971486 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,02180969 0,04966564 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,02180969 0,04961651 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,02180969 0,04956749 ! syncytium formation GO:0006949 15 11 0,000 0,02180969 0,04951855 ! plasma membrane organization GO:0007009 18 11 0,000 0,02180969 0,04946972 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,02180969 0,04942098 ! focal adhesion formation GO:0048041 24 11 0,000 0,02180969 0,04937234 ! mitotic spindle organization GO:0007052 15 11 0,000 0,02180969 0,04932379 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,02180969 0,04927534 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,02180969 0,04922698 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,02180969 0,04917872 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,02180969 0,04913055 ! adult heart development GO:0007512 11 11 0,000 0,02180969 0,04908248 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,02180969 0,0490345 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,02180969 0,04898662 ! temperature homeostasis GO:0001659 16 11 0,000 0,02180969 0,04893882 ! L-glutamate transport GO:0015813 16 11 0,000 0,02180969 0,04889113 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,02180969 0,04884352 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,02180969 0,04879601 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,02180969 0,04874859 ! stem cell development GO:0048864 29 11 0,000 0,02180969 0,04870126 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,02180969 0,04865402 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,02180969 0,04860688 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,02180969 0,04855982 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,02180969 0,04851286 ! vasoconstriction GO:0042310 15 11 0,000 0,02180969 0,04846599 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,02180969 0,0484192 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,02180969 0,04837251 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,02180969 0,04832591 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,02180969 0,0482794 ! ribosome assembly GO:0042255 13 11 0,000 0,02180969 0,04823298 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,02180969 0,04818664 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,02180969 0,0481404 ! chromatin silencing GO:0006342 19 11 0,000 0,02180969 0,04809424 ! nucleosome positioning GO:0016584 13 11 0,000 0,02180969 0,04804818 ! T cell homeostasis GO:0043029 20 11 0,000 0,02180969 0,0480022 ! regulation of isotype switching GO:0045191 19 11 0,000 0,02180969 0,04795631 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,02180969 0,0479105 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,02180969 0,04786479 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,02180969 0,04781916 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,02180969 0,04777361 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,02180969 0,04772816 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,02180969 0,04768279 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,02180969 0,04763751 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,02180969 0,04759231 ! male genitalia development GO:0030539 13 11 0,000 0,02180969 0,0475472 ! cholesterol efflux GO:0033344 19 11 0,000 0,02180969 0,04750217 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,02180969 0,04745723 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,02180969 0,04741238 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,02180969 0,04736761 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,02180969 0,04732292 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,02180969 0,04727832 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,02180969 0,0472338 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,02180969 0,04718937 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,02180969 0,04714501 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,02180969 0,04710075 ! lysogeny GO:0030069 18 11 0,000 0,02180969 0,04705656 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,02180969 0,04701246 ! acrosome reaction GO:0007340 13 11 0,000 0,02180969 0,04696844 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,02180969 0,0469245 ! lactation GO:0007595 20 12 0,000 0,02376932 0,05109293 ! reproductive cellular process GO:0048610 14 12 0,000 0,02376932 0,05104523 ! tRNA modification GO:0006400 14 12 0,000 0,02376932 0,05099761 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,02376932 0,05095008 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,02376932 0,05090264 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,02376932 0,05085529 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,02376932 0,05080803 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,02376932 0,05076085 ! non-recombinational repair GO:0000726 19 12 0,000 0,02376932 0,05071377 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,02376932 0,05066677 ! peroxisomal transport GO:0043574 21 12 0,000 0,02376932 0,05061985 ! cartilage condensation GO:0001502 18 12 0,000 0,02376932 0,05057302 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,02376932 0,05052628 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,02376932 0,05047963 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,02376932 0,05043306 ! heart looping GO:0001947 15 12 0,000 0,02376932 0,05038658 ! palate development GO:0060021 15 12 0,000 0,02376932 0,05034018 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,02376932 0,05029387 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,02376932 0,05024765 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,02376932 0,05020151 ! arginine metabolic process GO:0006525 13 12 0,000 0,02376932 0,05015545 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,02376932 0,05010948 ! methionine metabolic process GO:0006555 13 12 0,000 0,02376932 0,05006359 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,02376932 0,05001779 ! Golgi organization GO:0007030 18 12 0,000 0,02376932 0,04997207 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,02376932 0,04992643 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,02376932 0,04988088 ! monoamine transport GO:0015844 13 12 0,000 0,02376932 0,04983541 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02376932 0,04979002 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,02376932 0,04974471 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,02376932 0,04969949 ! L-amino acid transport GO:0015807 20 12 0,000 0,02376932 0,04965435 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,02376932 0,04960929 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,02376932 0,04956432 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,02376932 0,04951942 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,02376932 0,04947461 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,02376932 0,04942987 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,02376932 0,04938522 ! cerebellum development GO:0021549 13 12 0,000 0,02376932 0,04934065 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,02376932 0,04929616 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,02376932 0,04925175 ! histone acetylation GO:0016573 23 12 0,000 0,02376932 0,04920742 ! histone methylation GO:0016571 15 12 0,000 0,02376932 0,04916317 ! autonomic nervous system development GO:0048483 23 12 0,000 0,02376932 0,04911899 ! gland morphogenesis GO:0022612 23 12 0,000 0,02376932 0,0490749 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,02376932 0,04903089 ! peptidyl-lysine modification GO:0018205 18 12 0,000 0,02376932 0,04898695 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,02376932 0,0489431 ! response to gamma radiation GO:0010332 20 12 0,000 0,02376932 0,04889932 ! regulation of epidermis development GO:0045682 17 12 0,000 0,02376932 0,04885562 ! intestinal absorption GO:0050892 19 12 0,000 0,02376932 0,048812 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,02376932 0,04876846 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,02376932 0,04872499 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,02376932 0,0486816 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,02376932 0,04863829 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,02376932 0,04859506 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,02376932 0,0485519 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,02376932 0,04850882 ! microspike assembly GO:0030035 23 12 0,000 0,02376932 0,04846582 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,02376932 0,04842289 ! response to cold GO:0009409 14 12 0,000 0,02376932 0,04838003 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 0,02572514 0,0523146 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,02572514 0,05226839 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,02572514 0,05222225 ! cGMP metabolic process GO:0046068 16 13 0,000 0,02572514 0,0521762 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,02572514 0,05213023 ! water transport GO:0006833 17 13 0,000 0,02572514 0,05208434 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,02572514 0,05203853 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,02572514 0,05199281 ! lipid localization GO:0010876 24 13 0,000 0,02572514 0,05194716 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,02572514 0,05190159 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,02572514 0,0518561 ! organelle fusion GO:0048284 28 13 0,000 0,02572514 0,05181069 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,02572514 0,05176536 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,02572514 0,05172012 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,02572514 0,05167495 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,02572514 0,05162985 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,02572514 0,05158484 ! response to hexose stimulus GO:0009746 19 13 0,000 0,02572514 0,05153991 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,02572514 0,05149505 ! glutamate metabolic process GO:0006536 18 13 0,000 0,02572514 0,05145027 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,02572514 0,05140557 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,02572514 0,05136095 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,02572514 0,0513164 ! NAD metabolic process GO:0019674 21 13 0,000 0,02572514 0,05127193 ! exocrine system development GO:0035272 27 13 0,000 0,02572514 0,05122754 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,02572514 0,05118323 ! bone mineralization GO:0030282 15 13 0,000 0,02572514 0,05113899 ! regulation of exocytosis GO:0017157 17 13 0,000 0,02572514 0,05109483 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,02572514 0,05105074 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,02572514 0,05100673 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,02572514 0,0509628 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,02572514 0,05091894 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,02572514 0,05087516 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,02572514 0,05083145 ! genitalia development GO:0048806 15 13 0,000 0,02572514 0,05078782 ! regulation of cellular pH GO:0030641 20 13 0,000 0,02572514 0,05074426 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 0,02572514 0,05070078 ! cellular pigmentation GO:0033059 24 13 0,000 0,02572514 0,05065737 ! tissue regeneration GO:0042246 21 13 0,000 0,02572514 0,05061404 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,02572514 0,05057078 ! cofactor transport GO:0051181 19 13 0,000 0,02572514 0,05052759 ! NADP metabolic process GO:0006739 18 13 0,000 0,02572514 0,05048448 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,02572514 0,05044144 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,02572514 0,05039848 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,02572514 0,05035558 ! gas transport GO:0015669 18 13 0,000 0,02572514 0,05031277 ! regulation of RNA stability GO:0043487 28 13 0,000 0,02572514 0,05027002 ! heme biosynthetic process GO:0006783 20 13 0,000 0,02572514 0,05022734 ! regulation of axon extension GO:0030516 23 13 0,000 0,02572514 0,05018474 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,02572514 0,05014221 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,02572514 0,05009976 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,02572514 0,05005737 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,02572514 0,05001506 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,02572514 0,04997281 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,02572514 0,04993064 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,02767714 0,05367406 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,02767714 0,05362884 ! superoxide anion generation GO:0042554 18 14 0,000 0,02767714 0,05358369 ! neuron maturation GO:0042551 21 14 0,000 0,02767714 0,05353863 ! regulation of S phase GO:0033261 18 14 0,000 0,02767714 0,05349364 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,02767714 0,05344872 ! myotube differentiation GO:0014902 21 14 0,000 0,02767714 0,05340388 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 0,02767714 0,05335912 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,02767714 0,05331443 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,02767714 0,05326982 ! inositol metabolic process GO:0006020 20 14 0,000 0,02767714 0,05322528 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,02767714 0,05318081 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,02767714 0,05313642 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,02767714 0,0530921 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,02767714 0,05304786 ! gene silencing by RNA GO:0031047 20 14 0,000 0,02767714 0,05300369 ! response to cAMP GO:0051591 19 14 0,000 0,02767714 0,05295959 ! limbic system development GO:0021761 25 14 0,000 0,02767714 0,05291557 ! startle response GO:0001964 21 14 0,000 0,02767714 0,05287162 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,02767714 0,05282774 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,02767714 0,05278394 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,02767714 0,05274021 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,02767714 0,05269655 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,02767714 0,05265296 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,02767714 0,05260945 ! glycine metabolic process GO:0006544 22 14 0,000 0,02767714 0,052566 ! pituitary gland development GO:0021983 23 14 0,000 0,02767714 0,05252263 ! cellular response to starvation GO:0009267 21 14 0,000 0,02767714 0,05247933 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,02767714 0,0524361 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,02767714 0,05239295 ! regulation of heart rate GO:0002027 23 14 0,000 0,02767714 0,05234986 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,02767714 0,05230684 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,02767714 0,0522639 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,02767714 0,05222103 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,02767714 0,05217822 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,02767714 0,05213549 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,02767714 0,05209282 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,02767714 0,05205023 ! axon cargo transport GO:0008088 27 14 0,000 0,02767714 0,0520077 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,02767714 0,05196525 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,02767714 0,05192286 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,02767714 0,05188055 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,02767714 0,0518383 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,02767714 0,05179612 ! mRNA splice site selection GO:0006376 26 14 0,000 0,02767714 0,05175401 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,02767714 0,05171197 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,02767714 0,05166999 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,02767714 0,05162809 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,02767714 0,05158625 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,02767714 0,05154448 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,02767714 0,05150277 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,02767714 0,05146114 ! muscle maintenance GO:0046716 19 14 0,000 0,02767714 0,05141957 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,02767714 0,05137807 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,02767714 0,05133664 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,02767714 0,05129527 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,02767714 0,05125397 ! cell killing GO:0001906 20 14 0,000 0,02767714 0,05121273 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,02767714 0,05117157 ! cilium assembly GO:0042384 20 14 0,000 0,02767714 0,05113047 ! peptide hormone secretion GO:0030072 23 14 0,000 0,02767714 0,05108943 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,02962535 0,05464179 ! metencephalon development GO:0022037 19 15 0,000 0,02962535 0,054598 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,02962535 0,05455429 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,02962535 0,05451065 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,02962535 0,05446707 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,02962535 0,05442357 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,02962535 0,05438013 ! lipid phosphorylation GO:0046834 23 15 0,000 0,02962535 0,05433677 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,02962535 0,05429347 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,02962535 0,05425025 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,02962535 0,05420709 ! bile acid metabolic process GO:0008206 22 15 0,000 0,02962535 0,054164 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,02962535 0,05412098 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,02962535 0,05407802 ! adult walking behavior GO:0007628 25 15 0,000 0,02962535 0,05403514 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,02962535 0,05399232 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,02962535 0,05394957 ! myoblast differentiation GO:0045445 27 15 0,000 0,02962535 0,05390689 ! centrosome cycle GO:0007098 16 15 0,000 0,02962535 0,05386428 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,02962535 0,05382173 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,02962535 0,05377925 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,02962535 0,05373684 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,02962535 0,05369449 ! cerebral cortex development GO:0021987 29 15 0,000 0,02962535 0,05365221 ! response to osmotic stress GO:0006970 22 15 0,000 0,02962535 0,05361 ! vesicle coating GO:0006901 25 15 0,000 0,02962535 0,05356785 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,02962535 0,05352577 ! DNA integration GO:0015074 22 15 0,000 0,02962535 0,05348376 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,02962535 0,05344181 ! peptide secretion GO:0002790 27 15 0,000 0,02962535 0,05339993 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,02962535 0,05335811 ! regulation of vasodilation GO:0042312 24 15 0,000 0,02962535 0,05331636 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,02962535 0,05327467 ! neuron recognition GO:0008038 22 15 0,000 0,02962535 0,05323305 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,02962535 0,0531915 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,02962535 0,05315001 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,02962535 0,05310858 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,02962535 0,05306722 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,02962535 0,05302592 ! biomineral formation GO:0031214 18 15 0,000 0,02962535 0,05298469 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,02962535 0,05294352 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,02962535 0,05290241 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,02962535 0,05286137 ! dopamine metabolic process GO:0042417 30 15 0,000 0,02962535 0,05282039 ! organic cation transport GO:0015695 19 15 0,000 0,02962535 0,05277948 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,02962535 0,05273863 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,02962535 0,05269784 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,02962535 0,05265712 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! defense response to virus GO:0051607 27 15 0,000 0,02962535 0,05261645 ! peptide hormone processing GO:0016486 19 15 0,000 0,02962535 0,05257586 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,02962535 0,05253532 ! protein secretion GO:0009306 27 16 0,000 0,03156977 0,05594027 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,03156977 0,0558972 ! hormone secretion GO:0046879 25 16 0,000 0,03156977 0,0558542 ! bone remodeling GO:0046849 24 16 0,000 0,03156977 0,05581127 ! endothelial cell migration GO:0043542 22 16 0,000 0,03156977 0,05576841 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,03156977 0,05572561 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,03156977 0,05568287 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,03156977 0,0556402 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,03156977 0,0555976 ! glial cell development GO:0021782 24 16 0,000 0,03156977 0,05555506 ! patterning of blood vessels GO:0001569 24 16 0,000 0,03156977 0,05551259 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,03156977 0,05547018 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,03156977 0,05542784 ! protein polyubiquitination GO:0000209 26 16 0,000 0,03156977 0,05538556 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,03156977 0,05534334 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,03156977 0,05530119 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,03156977 0,05525911 ! fructose metabolic process GO:0006000 20 16 0,000 0,03156977 0,05521708 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,03156977 0,05517513 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,03156977 0,05513323 ! protein export from nucleus GO:0006611 24 16 0,000 0,03156977 0,0550914 ! negative regulation of immune response GO:0050777 28 16 0,000 0,03156977 0,05504963 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,03156977 0,05500793 ! DNA replication initiation GO:0006270 25 16 0,000 0,03156977 0,05496629 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,03156977 0,05492471 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,03156977 0,05488319 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,03156977 0,05484174 ! diencephalon development GO:0021536 25 16 0,000 0,03156977 0,05480035 ! oogenesis GO:0048477 23 16 0,000 0,03156977 0,05475902 ! neural crest cell migration GO:0001755 24 16 0,000 0,03156977 0,05471776 ! G1 phase GO:0051318 27 16 0,000 0,03156977 0,05467655 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,03156977 0,05463541 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,03156977 0,05459433 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,03156977 0,05455332 ! steroid catabolic process GO:0006706 22 16 0,000 0,03156977 0,05451236 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,03156977 0,05447147 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,03156977 0,05443063 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,03156977 0,05438986 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,03156977 0,05434915 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,03156977 0,0543085 ! sperm-egg recognition GO:0035036 16 16 0,000 0,03156977 0,05426791 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,03156977 0,05422738 ! nerve development GO:0021675 18 16 0,000 0,03156977 0,05418691 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,03156977 0,05414651 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,03156977 0,05410616 ! negative regulation of translation GO:0017148 22 16 0,000 0,03156977 0,05406587 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,0335104 0,05734666 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,0335104 0,05730403 ! negative regulation of defense response GO:0031348 19 17 0,000 0,0335104 0,05726145 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,0335104 0,05721894 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,0335104 0,0571765 ! glycerol metabolic process GO:0006071 20 17 0,000 0,0335104 0,05713411 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,0335104 0,05709179 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,0335104 0,05704953 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,0335104 0,05700733 ! signal complex assembly GO:0007172 29 17 0,000 0,0335104 0,0569652 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,0335104 0,05692313 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,0335104 0,05688112 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,0335104 0,05683917 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,0335104 0,05679729 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,0335104 0,05675546 ! memory GO:0007613 25 17 0,000 0,0335104 0,0567137 ! keratinization GO:0031424 17 17 0,000 0,0335104 0,056672 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,0335104 0,05663036 ! retinoid metabolic process GO:0001523 22 17 0,000 0,0335104 0,05658878 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,0335104 0,05654726 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,0335104 0,0565058 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,0335104 0,05646441 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,0335104 0,05642307 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,0335104 0,0563818 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,0335104 0,05634058 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 0,000 0,0335104 0,05629943 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,0335104 0,05625833 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,0335104 0,0562173 ! membrane budding GO:0006900 29 17 0,000 0,0335104 0,05617632 ! heme metabolic process GO:0042168 27 17 0,000 0,0335104 0,05613541 ! actin filament bundle formation GO:0051017 26 17 0,000 0,0335104 0,05609455 ! neuromuscular junction development GO:0007528 23 17 0,000 0,0335104 0,05605376 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,0335104 0,05601302 ! body fluid secretion GO:0007589 27 17 0,000 0,0335104 0,05597234 ! stem cell differentiation GO:0048863 36 17 0,000 0,0335104 0,05593172 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,0335104 0,05589116 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,0335104 0,05585066 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,0335104 0,05581022 ! sensory perception of pain GO:0019233 23 17 0,000 0,0335104 0,05576984 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,0335104 0,05572951 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,0335104 0,05568925 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,0335104 0,05564904 ! synaptogenesis GO:0007416 24 17 0,000 0,0335104 0,05560889 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,0335104 0,05556879 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,0335104 0,05552876 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,0335104 0,05548878 ! cell-cell junction organization GO:0045216 25 17 0,000 0,0335104 0,05544886 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,0335104 0,055409 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,0335104 0,05536919 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,0335104 0,05532944 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,0335104 0,05528975 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,0335104 0,05525012 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,0335104 0,05521054 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,03544725 0,05835983 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,03544725 0,05831808 ! positive regulation of translation GO:0045727 28 18 0,000 0,03544725 0,0582764 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,03544725 0,05823477 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,03544725 0,0581932 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,03544725 0,0581517 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,03544725 0,05811025 ! cAMP metabolic process GO:0046058 33 18 0,000 0,03544725 0,05806886 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,03544725 0,05802753 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,03544725 0,05798626 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,03544725 0,05794504 ! axis specification GO:0009798 26 18 0,000 0,03544725 0,05790389 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,03544725 0,05786279 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,03544725 0,05782176 ! pancreas development GO:0031016 26 18 0,000 0,03544725 0,05778078 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,03544725 0,05773986 ! glutamine metabolic process GO:0006541 23 18 0,000 0,03544725 0,05769899 ! response to retinoic acid GO:0032526 25 18 0,000 0,03544725 0,05765819 ! pigmentation during development GO:0048066 31 18 0,000 0,03544725 0,05761744 ! central nervous system neuron development GO:0021954 30 18 0,000 0,03544725 0,05757675 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,03544725 0,05753612 ! fucose metabolic process GO:0006004 26 18 0,000 0,03544725 0,05749554 ! response to fungus GO:0009620 19 18 0,000 0,03544725 0,05745502 ! peptide cross-linking GO:0018149 31 18 0,000 0,03544725 0,05741456 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,03544725 0,05737416 ! heart process GO:0003015 27 18 0,000 0,03544725 0,05733381 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,03544725 0,05729352 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,03544725 0,05725328 ! visual learning GO:0008542 35 18 0,000 0,03544725 0,05721311 ! somitogenesis GO:0001756 24 18 0,000 0,03544725 0,05717299 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,03544725 0,05713292 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,03544725 0,05709291 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,03544725 0,05705296 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,03544725 0,05701306 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,03544725 0,05697322 ! vitamin transport GO:0051180 24 18 0,000 0,03544725 0,05693343 ! hormone transport GO:0009914 27 18 0,000 0,03544725 0,0568937 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,03544725 0,05685403 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,03544725 0,05681441 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,03544725 0,05677485 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,03544725 0,05673534 ! cell-cell recognition GO:0009988 20 18 0,000 0,03544725 0,05669588 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,03544725 0,05665648 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,03544725 0,05661714 ! regulation of glucose import GO:0046324 21 18 0,000 0,03544725 0,05657785 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,03544725 0,05653861 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,03544725 0,05649943 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,03544725 0,0564603 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,03544725 0,05642123 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,03738033 0,05945696 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,03738033 0,05941587 ! positive regulation of ossification GO:0045778 30 19 0,000 0,03738033 0,05937484 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,03738033 0,05933386 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,03738033 0,05929294 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,03738033 0,05925208 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,03738033 0,05921127 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,03738033 0,05917052 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,03738033 0,05912983 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,03738033 0,05908919 ! regeneration GO:0031099 32 19 0,000 0,03738033 0,0590486 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,03738033 0,05900808 ! response to alkaloid GO:0043279 32 19 0,000 0,03738033 0,0589676 ! sensory perception of taste GO:0050909 23 19 0,000 0,03738033 0,05892719 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,03738033 0,05888683 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 0,000 0,03738033 0,05884652 ! smooth muscle contraction GO:0006939 36 19 0,000 0,03738033 0,05880627 ! peroxisome organization GO:0007031 29 19 0,000 0,03738033 0,05876607 ! digestive system process GO:0022600 30 19 0,000 0,03738033 0,05872593 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,03738033 0,05868585 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,03738033 0,05864582 ! response to vitamin A GO:0033189 26 19 0,000 0,03738033 0,05860584 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,03738033 0,05856592 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,03738033 0,05852605 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,03738033 0,05848624 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,03738033 0,05844648 ! response to starvation GO:0042594 30 19 0,000 0,03738033 0,05840677 ! sex determination GO:0007530 29 19 0,000 0,03738033 0,05836712 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,03738033 0,05832752 ! plasma membrane fusion GO:0045026 23 19 0,000 0,03738033 0,05828798 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,03738033 0,05824849 ! cytolysis GO:0019835 20 19 0,000 0,03738033 0,05820905 ! renal system process GO:0003014 35 19 0,000 0,03738033 0,05816967 ! vasodilation GO:0042311 33 19 0,000 0,03738033 0,05813034 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,03738033 0,05809106 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,03738033 0,05805183 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,03738033 0,05801266 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,03738033 0,05797354 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,03738033 0,05793448 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,03738033 0,05789547 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,03738033 0,0578565 ! sarcomere organization GO:0045214 23 19 0,000 0,03738033 0,0578176 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,03738033 0,05777874 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,03738033 0,05773994 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,03738033 0,05770119 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,03738033 0,05766249 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,03738033 0,05762384 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,03738033 0,05758524 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,03738033 0,0575467 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,03738033 0,0575082 ! protein stabilization GO:0050821 26 19 0,000 0,03738033 0,05746976 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,03930965 0,06039559 ! iron ion transport GO:0006826 37 20 0,000 0,03930965 0,06035527 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,03930965 0,06031501 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,03930965 0,0602748 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,03930965 0,06023464 ! response to vitamin GO:0033273 29 20 0,000 0,03930965 0,06019454 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,03930965 0,06015449 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,03930965 0,06011449 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,03930965 0,06007455 ! spinal cord development GO:0021510 31 20 0,000 0,03930965 0,06003466 ! response to ethanol GO:0045471 37 20 0,000 0,03930965 0,05999482 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,03930965 0,05995504 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 0,000 0,03930965 0,05991531 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,03930965 0,05987563 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,03930965 0,059836 ! chromosome condensation GO:0030261 31 20 0,000 0,03930965 0,05979643 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,03930965 0,05975691 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,03930965 0,05971744 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,03930965 0,05967802 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,03930965 0,05963865 ! pallium development GO:0021543 38 20 0,000 0,03930965 0,05959934 ! DNA modification GO:0006304 28 20 0,000 0,03930965 0,05956008 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,03930965 0,05952087 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,03930965 0,05948171 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,03930965 0,0594426 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,03930965 0,05940355 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,03930965 0,05936454 ! collagen catabolic process GO:0030574 25 20 0,000 0,03930965 0,05932559 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,03930965 0,05928669 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,03930965 0,05924784 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,03930965 0,05920904 ! alditol metabolic process GO:0019400 24 20 0,000 0,03930965 0,05917029 ! actin filament-based movement GO:0030048 34 20 0,000 0,03930965 0,05913159 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,04123521 0,06198758 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,04123521 0,06194709 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,04123521 0,06190665 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,04123521 0,06186627 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,04123521 0,06182594 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,04123521 0,06178566 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,04123521 0,06174544 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,04123521 0,06170526 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,04123521 0,06166514 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,04123521 0,06162508 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,04123521 0,06158506 ! protein amino acid acylation GO:0043543 37 21 0,000 0,04123521 0,06154509 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,04123521 0,06150518 ! vesicle docking GO:0048278 27 21 0,000 0,04123521 0,06146532 ! phototransduction GO:0007602 25 21 0,000 0,04123521 0,06142551 ! dendrite development GO:0016358 35 21 0,000 0,04123521 0,06138575 ! visual behavior GO:0007632 39 21 0,000 0,04123521 0,06134605 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,04123521 0,06130639 ! ovarian follicle development GO:0001541 30 21 0,000 0,04123521 0,06126679 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,04123521 0,06122724 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,04123521 0,06118774 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,04123521 0,06114829 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,04123521 0,06110889 ! cell aging GO:0007569 32 21 0,000 0,04123521 0,06106954 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,04123521 0,06103024 ! response to endoplasmic reticulum stress GO:0034976 25 21 0,000 0,04123521 0,06099099 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,04123521 0,06095179 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,04123521 0,06091265 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,04123521 0,06087355 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,04123521 0,0608345 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,04123521 0,06079551 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,04123521 0,06075656 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,04123521 0,06071766 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,04123521 0,06067882 ! fatty acid transport GO:0015908 30 21 0,000 0,04123521 0,06064002 ! immunoglobulin production GO:0002377 33 21 0,000 0,04123521 0,06060127 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,04123521 0,06056257 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,04123521 0,06052393 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,04123521 0,06048533 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,04123521 0,06044678 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,04123521 0,06040827 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,04123521 0,06036982 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,04123521 0,06033142 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,04123521 0,06029307 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,04123521 0,06025476 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,04123521 0,0602165 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,04123521 0,06017829 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,04123521 0,06014013 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,04123521 0,06010202 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,04315703 0,06286331 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,04315703 0,06282352 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,04315703 0,06278378 ! viral genome replication GO:0019079 29 22 0,000 0,04315703 0,0627441 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,04315703 0,06270446 ! leukocyte adhesion GO:0007159 38 22 0,000 0,04315703 0,06266487 ! molting cycle process GO:0022404 40 22 0,000 0,04315703 0,06262534 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,04315703 0,06258585 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,04315703 0,06254641 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,04315703 0,06250703 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,04315703 0,06246769 ! vasculogenesis GO:0001570 33 22 0,000 0,04315703 0,0624284 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,04315703 0,06238916 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,04315703 0,06234997 GO:0010810|regulation of cell-substrate adhesion, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,04315703 0,06231083 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,04315703 0,06227174 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,04315703 0,0622327 ! lysosome organization GO:0007040 37 22 0,000 0,04315703 0,06219371 ! ureteric bud development GO:0001657 32 22 0,000 0,04315703 0,06215477 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,04315703 0,06211587 ! regulation of behavior GO:0050795 38 22 0,000 0,04315703 0,06207702 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,04315703 0,06203822 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,04315703 0,06199948 ! membrane depolarization GO:0051899 35 22 0,000 0,04315703 0,06196077 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,04315703 0,06192212 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,04315703 0,06188352 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,04315703 0,06184496 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,04315703 0,06180645 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,04315703 0,06176799 ! blastocyst development GO:0001824 37 22 0,000 0,04315703 0,06172958 ! neural tube closure GO:0001843 33 22 0,000 0,04315703 0,06169121 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,04315703 0,06165289 ! protein tetramerization GO:0051262 39 22 0,000 0,04315703 0,06161462 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,0450751 0,0643131 ! neuron fate commitment GO:0048663 32 23 0,000 0,0450751 0,06427323 ! embryonic pattern specification GO:0009880 31 23 0,000 0,0450751 0,06423341 ! positive regulation of cell adhesion GO:0045785 37 23 0,000 0,0450751 0,06419364 ! myelination GO:0042552 35 23 0,000 0,0450751 0,06415391 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,0450751 0,06411424 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,0450751 0,06407461 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,0450751 0,06403503 ! ER-nuclear signaling pathway GO:0006984 27 23 0,000 0,0450751 0,06399551 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,0450751 0,06395603 ! vesicle targeting GO:0006903 32 23 0,000 0,0450751 0,0639166 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,0450751 0,06387722 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,0450751 0,06383788 ! osteoblast differentiation GO:0001649 40 23 0,000 0,0450751 0,0637986 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,0450751 0,06375936 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,0450751 0,06372017 ! interaction with host GO:0051701 37 23 0,000 0,0450751 0,06368103 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,0450751 0,06364194 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,0450751 0,0636029 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,0450751 0,0635639 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,0450751 0,06352495 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,0450751 0,06348605 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,0450751 0,0634472 ! cell fate determination GO:0001709 45 23 0,000 0,0450751 0,06340839 ! pentose metabolic process GO:0019321 31 23 0,000 0,0450751 0,06336963 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,0450751 0,06333092 ! spermatid development GO:0007286 33 23 0,000 0,0450751 0,06329226 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,0450751 0,06325364 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,0450751 0,06321507 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,0450751 0,06317655 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,0450751 0,06313808 ! telomere organization GO:0032200 32 23 0,000 0,0450751 0,06309965 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,0450751 0,06306127 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,0450751 0,06302293 ! regulation of amine transport GO:0051952 38 23 0,000 0,0450751 0,06298464 ! liver development GO:0001889 40 23 0,000 0,0450751 0,0629464 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,04698943 0,06557991 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,04698943 0,06554014 ! initiation of viral infection GO:0019059 42 24 0,000 0,04698943 0,06550042 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,04698943 0,06546075 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,04698943 0,06542112 ! superoxide metabolic process GO:0006801 32 24 0,000 0,04698943 0,06538154 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,04698943 0,06534201 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,04698943 0,06530253 ! fat cell differentiation GO:0045444 37 24 0,000 0,04698943 0,0652631 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,04698943 0,06522371 ! sperm motility GO:0030317 27 24 0,000 0,04698943 0,06518437 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,04698943 0,06514508 ! vacuole organization GO:0007033 39 24 0,000 0,04698943 0,06510584 ! receptor metabolic process GO:0043112 37 24 0,000 0,04698943 0,06506664 ! neural crest cell development GO:0014032 39 24 0,000 0,04698943 0,06502749 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,04698943 0,06498839 ! primary neural tube formation GO:0014020 35 24 0,000 0,04698943 0,06494933 ! negative regulation of cell development GO:0010721 56 24 0,000 0,04698943 0,06491033 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,04698943 0,06487136 ! base-excision repair GO:0006284 31 24 0,000 0,04698943 0,06483245 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,04698943 0,06479358 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,04698943 0,06475476 ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,04698943 0,06471598 ! glutathione metabolic process GO:0006749 29 24 0,000 0,04698943 0,06467725 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,04698943 0,06463857 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,04698943 0,06459994 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,04698943 0,06456134 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,04890004 0,06714632 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,04890004 0,06710626 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,04890004 0,06706624 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,04890004 0,06702627 ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,04890004 0,06698635 ! peptide transport GO:0015833 43 25 0,000 0,04890004 0,06694648 ! male gonad development GO:0008584 33 25 0,000 0,04890004 0,06690665 ! iron ion homeostasis GO:0055072 39 25 0,000 0,04890004 0,06686688 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,04890004 0,06682715 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,04890004 0,06678746 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,04890004 0,06674783 ! phospholipid transport GO:0015914 35 25 0,000 0,04890004 0,06670824 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,04890004 0,06666869 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,04890004 0,0666292 ! detection of light stimulus GO:0009583 30 25 0,000 0,04890004 0,06658975 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,04890004 0,06655035 GO:0045840|positive regulation of mitosis, ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,04890004 0,06651099 ! leukocyte proliferation GO:0070661 39 25 0,000 0,04890004 0,06647168 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,04890004 0,06643242 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,05080692 0,06898224 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,05080692 0,06894155 ! translational initiation GO:0006413 43 26 0,000 0,05080692 0,0689009 ! regulation of pH GO:0006885 36 26 0,000 0,05080692 0,0688603 ! circadian rhythm GO:0007623 42 26 0,000 0,05080692 0,06881974 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,05080692 0,06877924 ! post-embryonic development GO:0009791 42 26 0,000 0,05080692 0,06873878 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,05080692 0,06869837 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,05080692 0,068658 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,05080692 0,06861769 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,05080692 0,06857742 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,05080692 0,0685372 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,05080692 0,06849702 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,05080692 0,0684569 ! regulation of coagulation GO:0050818 39 26 0,000 0,05080692 0,06841682 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,05271009 0,0709381 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,05271009 0,07089662 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,05271009 0,07085518 ! membrane docking GO:0022406 39 27 0,000 0,05271009 0,07081379 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,05271009 0,07077246 ! catechol metabolic process GO:0009712 43 27 0,000 0,05271009 0,07073117 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,05271009 0,07068992 ! acute-phase response GO:0006953 42 27 0,000 0,05271009 0,07064873 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,05271009 0,07060758 ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,05271009 0,07056648 ! response to ionizing radiation GO:0010212 47 27 0,000 0,05271009 0,07052543 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,05271009 0,07048443 ! natural killer cell activation GO:0030101 35 27 0,000 0,05271009 0,07044347 ! lipid oxidation GO:0034440 38 27 0,000 0,05271009 0,07040256 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,05271009 0,0703617 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,05271009 0,07032089 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,05271009 0,07028013 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,05271009 0,07023941 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,05271009 0,07019874 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,05271009 0,07015811 ! gene silencing GO:0016458 41 27 0,000 0,05271009 0,07011753 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,05460956 0,0726023 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,05460956 0,07256036 ! phenol metabolic process GO:0018958 44 28 0,000 0,05460956 0,07251847 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,05460956 0,07247662 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,05460956 0,07243482 ! cell junction assembly GO:0034329 56 28 0,000 0,05460956 0,07239307 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,05460956 0,07235137 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,05460956 0,07230972 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,05460956 0,07226812 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,05460956 0,07222656 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,05460956 0,07218505 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,05460956 0,07214359 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,05460956 0,07210217 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,05460956 0,07206081 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,05460956 0,07201949 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,05460956 0,07197821 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,05460956 0,07193699 ! mesoderm formation GO:0001707 46 28 0,000 0,05460956 0,07189581 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,05460956 0,07185468 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,05460956 0,0718136 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,05460956 0,07177256 ! ensheathment of neurons GO:0007272 43 28 0,000 0,05460956 0,07173157 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,05460956 0,07169063 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,05460956 0,07164973 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,05460956 0,07160889 ! neural tube formation GO:0001841 41 28 0,000 0,05460956 0,07156808 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,05460956 0,07152733 ! placenta development GO:0001890 37 28 0,000 0,05460956 0,07148662 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,05650532 0,07392619 ! regulation of innate immune response GO:0045088 38 29 0,000 0,05650532 0,07388416 ! ovulation cycle process GO:0022602 41 29 0,000 0,05650532 0,07384218 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,05650532 0,07380025 ! protein targeting to membrane GO:0006612 53 29 0,000 0,05650532 0,07375837 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,05650532 0,07371653 ! mismatch repair GO:0006298 34 29 0,000 0,05650532 0,07367474 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,05650532 0,073633 ! formation of primary germ layer GO:0001704 48 29 0,000 0,05650532 0,0735913 ! telencephalon development GO:0021537 52 29 0,000 0,05650532 0,07354966 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,05650532 0,07350806 ! eye morphogenesis GO:0048592 51 29 0,000 0,05650532 0,0734665 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,05650532 0,073425 ! tissue homeostasis GO:0001894 42 29 0,000 0,05650532 0,07338354 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,05839739 0,07579797 ! collagen metabolic process GO:0032963 40 30 0,000 0,05839739 0,07575522 ! organic anion transport GO:0015711 51 30 0,000 0,05839739 0,07571252 ! cholesterol transport GO:0030301 46 30 0,000 0,05839739 0,07566986 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,05839739 0,07562725 ! spliceosome assembly GO:0000245 49 30 0,000 0,05839739 0,0755847 ! spindle organization GO:0007051 37 30 0,000 0,05839739 0,07554218 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,05839739 0,07549972 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,05839739 0,07545731 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,05839739 0,07541494 ! ceramide metabolic process GO:0006672 43 30 0,000 0,05839739 0,07537262 ! ovulation cycle GO:0042698 43 30 0,000 0,05839739 0,07533034 ! hindbrain development GO:0030902 45 30 0,000 0,05839739 0,07528812 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,05839739 0,07524594 ! adult locomotory behavior GO:0008344 47 30 0,000 0,05839739 0,07520381 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,05839739 0,07516173 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,05839739 0,07511969 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,05839739 0,0750777 ! response to heat GO:0009408 41 30 0,000 0,05839739 0,07503576 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,05839739 0,07499386 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,05839739 0,07495201 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,06028578 0,07733257 ! negative regulation of secretion GO:0051048 49 31 0,000 0,06028578 0,07728946 ! mammary gland development GO:0030879 57 31 0,000 0,06028578 0,0772464 ! glial cell differentiation GO:0010001 55 31 0,000 0,06028578 0,07720339 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,06028578 0,07716043 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,06028578 0,07711751 ! odontogenesis GO:0042476 50 31 0,000 0,06028578 0,07707465 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,06028578 0,07703183 ! segmentation GO:0035282 41 31 0,000 0,06028578 0,07698906 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,06028578 0,07694633 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,06028578 0,07690365 ! metanephros development GO:0001656 58 31 0,000 0,06028578 0,07686103 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,06028578 0,07681844 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,06028578 0,07677591 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,06028578 0,07673342 ! cell fate specification GO:0001708 37 31 0,000 0,06028578 0,07669098 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,06028578 0,07664858 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,06028578 0,07660624 ! RNA modification GO:0009451 40 31 0,000 0,06028578 0,07656394 ! regulation of muscle development GO:0048634 48 32 0,000 0,06217048 0,07891397 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,06217048 0,07887044 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,06217048 0,07882696 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,06217048 0,07878353 ! meiosis I GO:0007127 52 32 0,000 0,06217048 0,07874015 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,06217048 0,07869681 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,06217048 0,07865353 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,06217048 0,07861029 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,06217048 0,07856709 ! peripheral nervous system development GO:0007422 53 32 0,000 0,06217048 0,07852395 ! regulation of protein stability GO:0031647 48 32 0,000 0,06217048 0,07848085 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,06217048 0,0784378 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,06217048 0,0783948 ! cytokine production GO:0001816 44 32 0,000 0,06217048 0,07835184 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,06217048 0,07830893 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,06217048 0,07826607 ! vesicle localization GO:0051648 47 32 0,000 0,06217048 0,07822326 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,06405152 0,08054592 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,06405152 0,08050191 ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,06405152 0,08045794 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,06405152 0,08041402 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,06405152 0,08037015 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,06405152 0,08032633 ! sister chromatid segregation GO:0000819 46 33 0,000 0,06405152 0,08028256 ! ear morphogenesis GO:0042471 42 33 0,000 0,06405152 0,08023883 ! cell junction organization GO:0034330 63 33 0,000 0,06405152 0,08019515 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,06405152 0,08015152 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,06405152 0,08010793 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,06405152 0,0800644 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 0,000 0,06405152 0,08002091 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,06405152 0,07997746 ! female gonad development GO:0008585 49 33 0,000 0,06405152 0,07993407 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,06405152 0,07989072 ! positive regulation of cell development GO:0010720 54 33 0,000 0,06405152 0,07984742 ! lipid homeostasis GO:0055088 55 33 0,000 0,06405152 0,07980417 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,06405152 0,07976096 ! regulation of proteolysis GO:0030162 50 33 0,000 0,06405152 0,0797178 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,06405152 0,07967468 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,06405152 0,07963162 ! cytokinesis GO:0000910 52 33 0,000 0,06405152 0,0795886 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,06405152 0,07954562 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,06592889 0,08183294 ! mRNA catabolic process GO:0006402 48 34 0,000 0,06592889 0,0817888 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,06592889 0,08174471 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,06592889 0,08170067 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,06592889 0,08165667 ! feeding behavior GO:0007631 45 34 0,000 0,06592889 0,08161272 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,06592889 0,08156882 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,06592889 0,08152497 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,06592889 0,08148116 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,06592889 0,0814374 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,06592889 0,08139369 ! neuron migration GO:0001764 46 34 0,000 0,06592889 0,08135002 ! female gamete generation GO:0007292 43 34 0,000 0,06592889 0,0813064 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,06592889 0,08126283 ! polyol metabolic process GO:0019751 44 34 0,000 0,06592889 0,0812193 ! aerobic respiration GO:0009060 47 34 0,000 0,06592889 0,08117582 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,06592889 0,08113239 ! embryonic organ development GO:0048568 45 34 0,000 0,06592889 0,081089 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,06592889 0,08104566 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,0678026 0,08330447 ! Notch signaling pathway GO:0007219 56 35 0,000 0,0678026 0,08325999 ! regulation of intracellular protein transport GO:0033157 59 35 0,000 0,0678026 0,08321557 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,0678026 0,08317118 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,0678026 0,08312685 GO:0032313|regulation of Rab GTPase activity, ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,0678026 0,08308256 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,0678026 0,08303832 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,0678026 0,08299413 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,0678026 0,08294998 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,0678026 0,08290588 ! glycogen metabolic process GO:0005977 48 35 0,000 0,0678026 0,08286183 ! pigment metabolic process GO:0042440 61 35 0,000 0,0678026 0,08281783 ! protein homooligomerization GO:0051260 52 35 0,000 0,0678026 0,08277387 ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,06967265 0,08501173 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 0,000 0,06967265 0,08496665 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,06967265 0,08492162 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,06967265 0,08487664 ! negative regulation of binding GO:0051100 58 36 0,000 0,06967265 0,08483171 ! organic ether metabolic process GO:0018904 46 36 0,000 0,06967265 0,08478683 ! tissue remodeling GO:0048771 62 36 0,000 0,06967265 0,08474199 ! neural tube development GO:0021915 50 36 0,000 0,06967265 0,0846972 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,06967265 0,08465246 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,06967265 0,08460776 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,06967265 0,08456312 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,06967265 0,08451851 ! glucan metabolic process GO:0044042 49 36 0,000 0,06967265 0,08447396 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,07153907 0,08669118 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,07153907 0,08664553 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,07153907 0,08659992 ! learning GO:0007612 67 37 0,000 0,07153907 0,08655437 ! ion transmembrane transport GO:0034220 56 37 0,000 0,07153907 0,08650886 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,07153907 0,0864634 ! regulation of protein secretion GO:0050708 51 37 0,000 0,07153907 0,08641799 ! amino acid activation GO:0043038 52 37 0,000 0,07153907 0,08637263 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,07153907 0,08632731 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,07340184 0,08852871 ! gliogenesis GO:0042063 71 38 0,000 0,07340184 0,08848231 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,07340184 0,08843596 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,07340184 0,08838965 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,07340184 0,0883434 ! phagocytosis GO:0006909 60 38 0,000 0,07340184 0,0882972 ! mesenchymal cell development GO:0014031 64 38 0,000 0,07340184 0,08825104 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 0,000 0,07340184 0,08820493 ! maintenance of location in cell GO:0051651 69 38 0,000 0,07340184 0,08815887 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,07526099 0,09034461 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,07526099 0,09029748 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,07526099 0,0902504 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,07526099 0,09020337 ! regulation of epithelial cell proliferation GO:0050678 71 39 0,000 0,07526099 0,09015639 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,07526099 0,09010946 ! male sex differentiation GO:0046661 53 39 0,000 0,07526099 0,09006258 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,07526099 0,09001574 ! chromatin remodeling GO:0006338 68 39 0,000 0,07526099 0,08996896 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,07526099 0,08992222 ! JNK cascade GO:0007254 54 39 0,000 0,07526099 0,08987553 ! developmental growth GO:0048589 62 39 0,000 0,07526099 0,08982889 ! cell growth GO:0016049 61 39 0,000 0,07526099 0,0897823 ! synapse organization GO:0050808 55 39 0,000 0,07526099 0,08973576 ! response to calcium ion GO:0051592 58 40 0,000 0,07711651 0,09190051 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,07711651 0,09185291 ! regulation of tube size GO:0035150 60 40 0,000 0,07711651 0,09180537 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,07711651 0,09175788 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,07711651 0,09171043 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,07711651 0,09166304 ! peptide metabolic process GO:0006518 56 40 0,000 0,07711651 0,09161569 ! inner ear development GO:0048839 57 40 0,000 0,07711651 0,09156839 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,07711651 0,09152114 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,07711651 0,09147394 ! double-strand break repair GO:0006302 67 40 0,000 0,07711651 0,09142679 ! B cell differentiation GO:0030183 62 40 0,000 0,07711651 0,09137969 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,07711651 0,09133263 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,07711651 0,09128563 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,07711651 0,09123867 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,07896842 0,09338167 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,07896842 0,09333369 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,07896842 0,09328575 ! glucose transport GO:0015758 52 41 0,000 0,07896842 0,09323786 ! endosome transport GO:0016197 71 41 0,000 0,07896842 0,09319002 ! striated muscle contraction GO:0006941 62 41 0,000 0,07896842 0,09314223 ! positive regulation of DNA binding GO:0043388 57 41 0,000 0,07896842 0,09309449 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,07896842 0,0930468 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,07896842 0,09299916 ! biopolymer methylation GO:0043414 62 41 0,000 0,07896842 0,09295156 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,07896842 0,09290402 ! mitochondrial transport GO:0006839 60 42 0,000 0,08081671 0,09502987 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 0,000 0,08081671 0,09498132 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,08081671 0,09493281 ! cellular component disassembly GO:0022411 64 42 0,000 0,08081671 0,09488435 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,08081671 0,09483594 ! hexose transport GO:0008645 54 42 0,000 0,08081671 0,09478757 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,08081671 0,09473926 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,08081671 0,094691 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,08081671 0,09464279 ! excretion GO:0007588 63 42 0,000 0,08081671 0,09459462 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,08081671 0,09454651 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,08081671 0,09449844 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,08081671 0,09445042 ! regulation of cell shape GO:0008360 78 42 0,000 0,08081671 0,09440245 ! positive regulation of binding GO:0051099 59 43 0,000 0,0826614 0,09650824 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,0826614 0,09645927 ! leukocyte migration GO:0050900 60 43 0,000 0,0826614 0,09641036 ! neuromuscular process GO:0050905 79 43 0,000 0,0826614 0,09636149 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,0826614 0,09631268 ! tRNA processing GO:0008033 49 43 0,000 0,0826614 0,09626391 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,0826614 0,09621519 ! vesicle organization GO:0016050 79 43 0,000 0,0826614 0,09616653 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,0826614 0,09611791 ! methylation GO:0032259 64 43 0,000 0,0826614 0,09606934 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,0845025 0,09815947 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,0845025 0,09810991 ! glycolysis GO:0006096 53 44 0,000 0,0845025 0,09806041 ! regulation of action potential GO:0001508 71 44 0,000 0,0845025 0,09801096 ! regulation of ion transport GO:0043269 57 44 0,000 0,0845025 0,09796156 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,0845025 0,09791221 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,0845025 0,09786291 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,0845025 0,09781366 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,0845025 0,09776446 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,0845025 0,0977153 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,0845025 0,0976662 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,0845025 0,09761715 ! positive regulation of cell cycle GO:0045787 77 45 0,000 0,08634 0,09968976 ! RNA catabolic process GO:0006401 64 45 0,000 0,08634 0,09963974 ! positive regulation of defense response GO:0031349 59 45 0,000 0,08634 0,09958977 ! regulation of translational initiation GO:0006446 64 45 0,000 0,08634 0,09953985 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,08634 0,09948998 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,08634 0,09944016 ! cell recognition GO:0008037 58 45 0,000 0,08634 0,09939039 ! cell maturation GO:0048469 60 45 0,000 0,08634 0,09934067 ! protein amino acid autophosphorylation GO:0046777 80 45 0,000 0,08634 0,099291 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,08817392 0,10134934 ! cell redox homeostasis GO:0045454 63 46 0,000 0,08817392 0,10129871 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,08817392 0,10124814 ! regulation of ossification GO:0030278 71 46 0,000 0,08817392 0,10119762 ! histone modification GO:0016570 68 46 0,000 0,08817392 0,10114714 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,08817392 0,10109672 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,09000427 0,10314391 ! viral infectious cycle GO:0019058 71 47 0,000 0,09000427 0,10309254 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,09000427 0,10304122 ! endocrine system development GO:0035270 83 47 0,000 0,09000427 0,10298996 ! covalent chromatin modification GO:0016569 75 47 0,000 0,09000427 0,10293875 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,09000427 0,10288758 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,09000427 0,10283647 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,09000427 0,10278541 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,09000427 0,1027344 ! chloride transport GO:0006821 67 48 0,000 0,09183105 0,10476756 ! regulation of muscle contraction GO:0006937 69 48 0,000 0,09183105 0,10471562 ! response to temperature stimulus GO:0009266 62 48 0,000 0,09183105 0,10466373 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,09183105 0,10461189 ! gastrulation GO:0007369 73 48 0,000 0,09183105 0,1045601 ! heart morphogenesis GO:0003007 65 48 0,000 0,09183105 0,10450837 ! regulation of DNA replication GO:0006275 75 48 0,000 0,09183105 0,10445668 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,09183105 0,10440505 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,09183105 0,10435346 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,09183105 0,10430193 ! regulation of endocytosis GO:0030100 63 48 0,000 0,09183105 0,10425045 ! nuclear export GO:0051168 69 48 0,000 0,09183105 0,10419902 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,09183105 0,10414764 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,09183105 0,10409631 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,09365426 0,10611074 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,09365426 0,10605849 ! sensory perception of smell GO:0007608 61 49 0,000 0,09365426 0,1060063 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,09365426 0,10595416 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,09365426 0,10590206 ! RNA elongation GO:0006354 62 49 0,000 0,09365426 0,10585002 ! regulation of intracellular transport GO:0032386 78 49 0,000 0,09365426 0,10579803 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,09365426 0,1057461 ! germ cell development GO:0007281 68 49 0,000 0,09365426 0,10569421 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,09365426 0,10564237 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,09365426 0,10559059 ! cartilage development GO:0051216 70 49 0,000 0,09365426 0,10553885 ! maintenance of location GO:0051235 84 49 0,000 0,09365426 0,10548717 ! ear development GO:0043583 72 50 0,000 0,09547392 0,1074841 ! membrane fusion GO:0006944 80 50 0,000 0,09547392 0,10743151 ! lipid modification GO:0030258 73 50 0,000 0,09547392 0,10737898 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,09547392 0,1073265 ! proton transport GO:0015992 75 50 0,000 0,09547392 0,10727407 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,09547392 0,10722169 ! positive regulation of secretion GO:0051047 71 51 0,000 0,09729003 0,10920794 ! hydrogen transport GO:0006818 77 51 0,000 0,09729003 0,10915466 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,09729003 0,10910144 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of cell migration GO:0030335 92 51 0,000 0,09729003 0,10904828 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,09729003 0,10899516 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,09729003 0,10894209 ! adult behavior GO:0030534 80 51 0,000 0,09729003 0,10888908 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,09729003 0,10883612 ! transition metal ion transport GO:0000041 74 52 0,000 0,09910259 0,1108099 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,09910259 0,11075606 ! aging GO:0007568 79 52 0,000 0,09910259 0,11070227 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,09910259 0,11064853 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,09910259 0,11059484 ! establishment of organelle localization GO:0051656 85 52 0,000 0,09910259 0,11054121 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,10091162 0,11250448 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,10091162 0,11244997 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,10091162 0,11239551 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,10091162 0,11234111 ! kidney development GO:0001822 90 53 0,000 0,10091162 0,11228676 ! single fertilization GO:0007338 59 53 0,000 0,10091162 0,11223246 ! cell projection assembly GO:0030031 76 53 0,000 0,10091162 0,11217822 ! amino acid transport GO:0006865 84 54 0,000 0,10271713 0,11413014 ! regulation of mitosis GO:0007088 84 54 0,000 0,10271713 0,11407503 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,10271713 0,11401998 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,10271713 0,11396497 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,10271713 0,11391002 ! DNA catabolic process GO:0006308 67 54 0,000 0,10271713 0,11385513 ! detection of external stimulus GO:0009581 66 54 0,000 0,10271713 0,11380029 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,10271713 0,11374549 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,10271713 0,11369076 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,10271713 0,11363607 ! exocytosis GO:0006887 74 55 0,000 0,10451911 0,11557401 ! mesoderm development GO:0007498 76 55 0,000 0,10451911 0,11551847 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,10451911 0,11546299 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,10451911 0,11540756 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,10631757 0,11733705 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,10631757 0,11728077 ! positive regulation of cell motion GO:0051272 99 56 0,000 0,10631757 0,11722455 ! carbohydrate transport GO:0008643 74 57 0,000 0,10811253 0,11914653 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,10811253 0,11908947 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 0,000 0,10811253 0,11903246 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,10811253 0,11897551 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,10811253 0,11891861 ! camera-type eye development GO:0043010 88 57 0,000 0,10811253 0,11886176 ! secondary metabolic process GO:0019748 84 57 0,000 0,10811253 0,11880497 ! developmental maturation GO:0021700 75 57 0,000 0,10811253 0,11874824 ! gonad development GO:0008406 79 57 0,000 0,10811253 0,11869156 ! viral reproductive process GO:0022415 87 58 0,000 0,10990398 0,12060074 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,10990398 0,12054323 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,10990398 0,12048577 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,10990398 0,12042837 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,11169193 0,12232926 ! activation of MAPK activity GO:0000187 84 59 0,000 0,11169193 0,12227104 ! lung development GO:0030324 94 59 0,000 0,11169193 0,12221287 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,11169193 0,12215476 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,11169193 0,1220967 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,1134764 0,12398847 ! phosphoinositide metabolic process GO:0030384 87 60 0,000 0,1134764 0,12392959 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,1134764 0,12387078 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,1134764 0,12381201 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,1134764 0,12375331 ! regulation of heart contraction GO:0008016 91 60 0,000 0,1134764 0,12369466 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,1134764 0,12363606 ! fertilization GO:0009566 68 60 0,000 0,1134764 0,12357752 ! regulation of homeostatic process GO:0032844 105 60 0,000 0,1134764 0,12351904 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,11525739 0,12539829 ! meiosis GO:0007126 96 61 0,000 0,11525739 0,125339 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 114 61 0,000 0,11525739 0,12527977 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,11525739 0,12522059 ! urogenital system development GO:0001655 101 61 0,000 0,11525739 0,12516147 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,11525739 0,1251024 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,11525739 0,12504339 ! extracellular matrix organization GO:0030198 103 61 0,000 0,11525739 0,12498444 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,11525739 0,12492554 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! amine catabolic process GO:0009310 90 62 0,000 0,1170349 0,1267924 ! neurotransmitter transport GO:0006836 81 62 0,000 0,1170349 0,1267327 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,1170349 0,12667307 ! respiratory tube development GO:0030323 99 62 0,000 0,1170349 0,12661348 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,1170349 0,12655396 ! meiotic cell cycle GO:0051321 97 62 0,000 0,1170349 0,12649448 ! organelle localization GO:0051640 96 62 0,000 0,1170349 0,12643507 ! regulation of transcription factor activity GO:0051090 97 63 0,000 0,11880894 0,12829134 GO:0090046|regulation of transcription regulator activity, ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,11880894 0,12823114 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 0,000 0,11880894 0,12817099 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 0,000 0,11880894 0,1281109 ! viral reproduction GO:0016032 92 63 0,000 0,11880894 0,12805087 ! regulation of lipase activity GO:0060191 109 63 0,000 0,11880894 0,12799089 ! cell cycle checkpoint GO:0000075 108 64 0,000 0,12057951 0,12983749 ! appendage morphogenesis GO:0035107 93 64 0,000 0,12057951 0,12977674 GO:0035108|limb morphogenesis, ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 0,000 0,12057951 0,12971604 ! hexose catabolic process GO:0019320 82 64 0,000 0,12057951 0,12965539 ! respiratory system development GO:0060541 100 64 0,000 0,12057951 0,12959481 ! adaptive immune response GO:0002250 94 64 0,000 0,12057951 0,12953428 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 90 65 0,000 0,12234664 0,13137127 ! appendage development GO:0048736 94 65 0,000 0,12234664 0,13130997 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 0,000 0,12234664 0,13124872 ! defense response to bacterium GO:0042742 73 65 0,000 0,12234664 0,13118754 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,12234664 0,1311264 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,12234664 0,13106533 ! activation of immune response GO:0002253 83 65 0,000 0,12234664 0,13100431 ! protein oligomerization GO:0051259 100 65 0,000 0,12234664 0,13094335 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,12411031 0,13276917 ! antigen processing and presentation GO:0019882 96 66 0,000 0,12411031 0,13270744 ! axon guidance GO:0007411 99 66 0,000 0,12411031 0,13264577 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,12411031 0,13258417 ! regulation of immune effector process GO:0002697 101 66 0,000 0,12411031 0,13252261 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,12587054 0,13433978 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,12587054 0,13427747 ! acute inflammatory response GO:0002526 92 68 0,000 0,12762733 0,13608848 ! learning or memory GO:0007611 123 68 0,000 0,12762733 0,13602542 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,12762733 0,13596242 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,12762733 0,13589947 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,12762733 0,13583658 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,12762733 0,13577375 ! rhythmic process GO:0048511 105 68 0,000 0,12762733 0,13571098 ! inorganic anion transport GO:0015698 93 68 0,000 0,12762733 0,13564827 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,12938069 0,13744831 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,12938069 0,13738485 ! response to drug GO:0042493 108 69 0,000 0,12938069 0,13732145 ! response to metal ion GO:0010038 103 70 0,000 0,13113063 0,1391146 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,13113063 0,13905046 ! humoral immune response GO:0006959 86 70 0,000 0,13113063 0,13898638 ! eye development GO:0001654 111 70 0,000 0,13113063 0,13892236 ! amine transport GO:0015837 101 70 0,000 0,13113063 0,1388584 ! positive regulation of phosphorylation GO:0042327 102 70 0,000 0,13113063 0,1387945 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,13113063 0,13873066 ! regulation of catabolic process GO:0009894 106 70 0,000 0,13113063 0,13866687 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,13287715 0,14044919 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,13287715 0,14038468 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,13287715 0,14032022 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,13287715 0,14025583 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,13287715 0,14019149 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 0,000 0,13462026 0,14196543 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 132 72 0,000 0,13462026 0,14190037 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,13462026 0,14183536 ! negative regulation of transport GO:0051051 116 73 0,000 0,13635997 0,14360253 ! regulation of blood pressure GO:0008217 107 73 0,000 0,13635997 0,14353681 ! tube morphogenesis GO:0035239 118 73 0,000 0,13635997 0,14347115 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,13635997 0,14340554 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,13635997 0,14334 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,13809628 0,14509887 ! response to oxygen levels GO:0070482 137 74 0,000 0,13809628 0,14503262 ! digestion GO:0007586 97 74 0,000 0,13809628 0,14496642 ! protein import into nucleus GO:0006606 118 74 0,000 0,13809628 0,14490029 ! blood coagulation GO:0007596 116 75 0,000 0,13982919 0,14665168 GO:0050817|coagulation, ! response to inorganic substance GO:0010035 115 75 0,000 0,13982919 0,14658484 ! response to nutrient GO:0007584 104 75 0,000 0,13982919 0,14651806 ! nuclear import GO:0051170 121 75 0,000 0,13982919 0,14645134 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,13982919 0,14638468 ! amine biosynthetic process GO:0009309 97 76 0,000 0,14155873 0,14812788 ! tRNA metabolic process GO:0006399 95 76 0,000 0,14155873 0,14806051 ! response to unfolded protein GO:0006986 99 76 0,000 0,14155873 0,14799321 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,14155873 0,14792597 ! regulation of protein transport GO:0051223 114 76 0,000 0,14155873 0,1478588 GO:0070201|regulation of establishment of protein localization, ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,14328488 0,14959384 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,14328488 0,14952596 ! regulation of DNA binding GO:0051101 119 77 0,000 0,14328488 0,14945815 ! gland development GO:0048732 148 77 0,000 0,14328488 0,1493904 ! sex differentiation GO:0007548 105 77 0,000 0,14328488 0,14932271 ! protein ubiquitination GO:0016567 125 77 0,000 0,14328488 0,14925508 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,14328488 0,14918752 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,14328488 0,14912001 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,14328488 0,14905257 ! positive regulation of protein modification process GO:0031401 107 78 0,000 0,14500766 0,1507765 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,14500766 0,15070837 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,14500766 0,1506403 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,14672708 0,15235769 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,14672708 0,15228894 ! T cell activation GO:0042110 134 79 0,000 0,14672708 0,15222025 ! regulation of lyase activity GO:0051339 133 79 0,000 0,14672708 0,15215162 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,14672708 0,15208305 ! chromatin assembly GO:0031497 102 80 0,000 0,14844314 0,15379244 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,14844314 0,1537232 ! protein localization in nucleus GO:0034504 133 80 0,000 0,14844314 0,15365401 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,14844314 0,15358489 ! forebrain development GO:0030900 131 80 0,000 0,14844314 0,15351583 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,15015584 0,15521728 ! hemostasis GO:0007599 125 81 0,000 0,15015584 0,15514755 ! mRNA transport GO:0051028 121 81 0,000 0,15015584 0,15507788 ! regulation of cell cycle process GO:0010564 122 81 0,000 0,15015584 0,15500828 ! response to protein stimulus GO:0051789 111 81 0,000 0,15015584 0,15493873 ! regulation of neurological system process GO:0031644 122 81 0,000 0,15015584 0,15486925 ! vitamin metabolic process GO:0006766 103 81 0,000 0,15015584 0,15479984 ! ossification GO:0001503 134 82 0,000 0,1518652 0,15649192 GO:0060348|bone development, ! detection of stimulus GO:0051606 108 82 0,000 0,1518652 0,15642184 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,15357122 0,15810824 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,15357122 0,1580375 ! regulation of cell adhesion GO:0030155 159 83 0,000 0,15357122 0,15796682 ! regulation of defense response GO:0031347 117 84 0,000 0,1552739 0,15964684 ! microtubule cytoskeleton organization GO:0000226 120 84 0,000 0,1552739 0,1595755 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,1552739 0,15950423 ! sterol metabolic process GO:0016125 120 84 0,000 0,1552739 0,15943303 ! regulation of DNA metabolic process GO:0051052 135 85 0,000 0,15697326 0,16110598 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,15697326 0,16103412 ! rRNA metabolic process GO:0016072 107 85 0,000 0,15697326 0,16096233 GO:0006364|rRNA processing, ! positive regulation of MAP kinase activity GO:0043406 121 85 0,000 0,15697326 0,1608906 ! transcription initiation GO:0006352 118 85 0,000 0,15697326 0,16081893 ! anterior/posterior pattern formation GO:0009952 124 85 0,000 0,15697326 0,16074733 ! regulation of protein localization GO:0032880 132 85 0,000 0,15697326 0,16067579 ! regulation of membrane potential GO:0042391 128 85 0,000 0,15697326 0,16060431 ! negative regulation of multicellular organismal process GO:0051241 133 85 0,000 0,15697326 0,1605329 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,1586693 0,16219528 ! nucleosome organization GO:0034728 114 87 0,000 0,16036202 0,16385279 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,16036202 0,16378004 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,16036202 0,16370734 ! female pregnancy GO:0007565 130 87 0,000 0,16036202 0,16363471 ! Wnt receptor signaling pathway GO:0016055 130 87 0,000 0,16036202 0,16356215 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,16205143 0,16521201 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,16205143 0,16513881 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,16205143 0,16506567 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,16205143 0,1649926 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 0,000 0,16205143 0,1649196 ! regulation of neurogenesis GO:0050767 153 89 0,000 0,16373754 0,16656185 ! reproductive developmental process GO:0003006 127 89 0,000 0,16373754 0,16648821 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,16373754 0,16641465 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,16373754 0,16634114 ! regulation of T cell activation GO:0050863 128 89 0,000 0,16373754 0,1662677 ! leukocyte differentiation GO:0002521 143 90 0,000 0,16542035 0,16790239 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,16542035 0,16782833 ! hormone metabolic process GO:0042445 121 90 0,000 0,16542035 0,16775433 ! RNA localization GO:0006403 135 91 0,000 0,16709988 0,16938286 ! ATP metabolic process GO:0046034 137 91 0,000 0,16709988 0,16930825 ! response to virus GO:0009615 122 91 0,000 0,16709988 0,16923369 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,16877612 0,17085611 ! glycerophospholipid metabolic process GO:0006650 130 92 0,000 0,16877612 0,17078094 ! cell fate commitment GO:0045165 141 92 0,000 0,16877612 0,17070584 ! positive regulation of immune response GO:0050778 121 92 0,000 0,16877612 0,1706308 ! DNA recombination GO:0006310 146 92 0,000 0,16877612 0,17055583 ! sulfur metabolic process GO:0006790 118 92 0,000 0,16877612 0,17048093 ! peptidyl-amino acid modification GO:0018193 147 93 0,000 0,17044908 0,17209521 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,17044908 0,1720197 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,17044908 0,17194425 ! electron transport chain GO:0022900 123 94 0,000 0,17211878 0,17355247 ! response to oxidative stress GO:0006979 141 94 0,000 0,17211878 0,17347642 ! angiogenesis GO:0001525 149 95 0,000 0,1737852 0,17507927 ! carboxylic acid transport GO:0046942 147 95 0,000 0,1737852 0,17500261 GO:0015849|organic acid transport, ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,17544837 0,17660011 ! in utero embryonic development GO:0001701 147 96 0,000 0,17544837 0,17652286 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,17544837 0,17644567 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,17544837 0,17636856 ! protein maturation GO:0051604 129 96 0,000 0,17544837 0,17629151 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,17710829 0,17788169 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,17710829 0,17780404 ! calcium ion transport GO:0006816 167 99 0,000 0,18041839 0,18104812 ! extracellular structure organization GO:0043062 156 99 0,000 0,18041839 0,18096916 ! protein import GO:0017038 156 99 0,000 0,18041839 0,18089028 ! regulation of translation GO:0006417 151 100 0,000 0,18206858 0,18246525 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,18206858 0,18238578 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,18206858 0,18230638 ! divalent metal ion transport GO:0070838 171 100 0,000 0,18206858 0,18222704 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,18206858 0,18214778 ! protein localization in organelle GO:0033365 161 100 0,000 0,18206858 0,18206858