pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/6712-8-real-Van-De-Vijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of protein homodimerization activity GO:0043496 6 5 1,000 2,781E-05 0,05125333 ! regulation of caspase activity GO:0043281 41 41 2,000 4,164E-05 0,03837329 ! positive regulation of cell growth GO:0030307 6 6 1,000 4,167E-05 0,02560183 ! regulation of endopeptidase activity GO:0052548 42 42 2,000 4,48E-05 0,02064222 ! keratinocyte proliferation GO:0043616 7 7 1,000 5,829E-05 0,02148469 ! myofibril assembly GO:0030239 7 7 1,000 5,829E-05 0,01790391 GO:0055002|striated muscle cell development, ! regulation of peptidase activity GO:0052547 46 46 2,000 5,901E-05 0,01553599 ! muscle cell development GO:0055001 8 8 1,000 7,764E-05 0,01788656 ! release of cytochrome c from mitochondria GO:0001836 9 8 1,000 7,764E-05 0,01589916 ! positive regulation of cell size GO:0045793 9 9 1,000 9,973E-05 0,01837977 ! negative regulation of caspase activity GO:0043154 9 9 1,000 9,973E-05 0,01670888 ! apoptotic mitochondrial changes GO:0008637 11 10 1,000 1,245E-04 0,01912704 ! regulation of protein binding GO:0043393 11 10 1,000 1,245E-04 0,01765573 ! positive regulation of neuron apoptosis GO:0043525 10 10 1,000 1,245E-04 0,0163946 ! skin development GO:0043588 11 11 1,000 1,521E-04 0,01868387 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 1,000 1,521E-04 0,01751612 ! negative regulation of peptidase activity GO:0010466 12 12 1,000 1,823E-04 0,01976374 ! actomyosin structure organization GO:0031032 12 12 1,000 1,823E-04 0,01866576 ! barbed-end actin filament capping GO:0051016 12 12 1,000 1,823E-04 0,01768335 GO:0051693|actin filament capping, ! Ras protein signal transduction GO:0007265 69 67 2,000 1,824E-04 0,01680877 ! negative regulation of actin filament polymerization GO:0030837 13 13 1,000 2,152E-04 0,01888985 ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 1,000 2,152E-04 0,01803122 ! negative regulation of protein polymerization GO:0032272 14 14 1,000 2,509E-04 0,02010229 ! negative regulation of actin filament depolymerization GO:0030835 15 15 1,000 2,892E-04 0,02220695 ! negative regulation of protein complex assembly GO:0031333 15 15 1,000 2,892E-04 0,02131868 ! striated muscle cell differentiation GO:0051146 16 15 1,000 2,892E-04 0,02049873 ! insulin receptor signaling pathway GO:0008286 17 15 1,000 2,892E-04 0,01973951 ! spliceosomal snRNP biogenesis GO:0000387 16 16 1,000 3,302E-04 0,02173267 ! regulation of actin filament depolymerization GO:0030834 17 17 1,000 3,738E-04 0,02375799 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 1,000 4,202E-04 0,02581177 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 1,000 4,202E-04 0,02497914 ! negative regulation of hydrolase activity GO:0051346 21 21 1,000 5,75E-04 0,03311722 ! cellular response to insulin stimulus GO:0032869 23 21 1,000 5,75E-04 0,03211366 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 1,000 6,319E-04 0,03425283 ! negative regulation of protein complex disassembly GO:0043242 23 23 1,000 6,914E-04 0,03640784 ! positive regulation of growth GO:0045927 23 23 1,000 6,914E-04 0,03539651 ! regulation of actin filament polymerization GO:0030833 25 25 1,000 8,183E-04 0,04075866 ! induction of apoptosis by intracellular signals GO:0008629 26 26 1,000 8,856E-04 0,04295157 ! response to insulin stimulus GO:0032868 28 26 1,000 8,856E-04 0,04185025 ! activation of caspase activity GO:0006919 27 27 1,000 9,555E-04 0,04402561 ! keratinocyte differentiation GO:0030216 28 28 1,000 1,028E-03 0,04621098 ! regulation of protein polymerization GO:0032271 29 29 1,000 1,103E-03 0,04840531 ! positive regulation of peptidase activity GO:0010952 30 30 1,000 1,181E-03 0,05060763 GO:0043280|positive regulation of caspase activity, ! regulation of protein complex disassembly GO:0043244 30 30 1,000 1,181E-03 0,04945746 ! skeletal muscle fiber development GO:0048741 31 31 1,000 1,261E-03 0,05164338 ! negative regulation of cytoskeleton organization GO:0051494 32 31 1,000 1,261E-03 0,0505207 ! epidermal cell differentiation GO:0009913 31 31 1,000 1,261E-03 0,04944579 ! muscle fiber development GO:0048747 32 32 1,000 1,344E-03 0,05159334 ! regulation of protein complex assembly GO:0043254 33 33 1,000 1,429E-03 0,05374896 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 1,000 1,429E-03 0,05267398 ! regulation of neuron apoptosis GO:0043523 34 33 1,000 1,429E-03 0,05164116 ! regulation of actin filament length GO:0030832 34 34 1,000 1,517E-03 0,05376143 ! muscle cell differentiation GO:0042692 35 34 1,000 1,517E-03 0,05274706 ! response to peptide hormone stimulus GO:0043434 36 34 1,000 1,517E-03 0,05177026 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 1,000 1,607E-03 0,0538573 ! regulation of cellular component size GO:0032535 35 35 1,000 1,607E-03 0,05289556 ! negative regulation of protein kinase activity GO:0006469 37 37 1,000 1,796E-03 0,05805608 ! DNA damage response, signal transduction GO:0042770 37 37 1,000 1,796E-03 0,05705512 ! negative regulation of kinase activity GO:0033673 38 38 1,000 1,893E-03 0,05914673 ! negative regulation of transferase activity GO:0051348 40 40 1,000 2,097E-03 0,06440637 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 1,000 2,31E-03 0,06979382 ! mitochondrion organization GO:0007005 44 43 1,000 2,42E-03 0,07194801 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 1,000 2,533E-03 0,07410583 ! negative regulation of organelle organization GO:0010639 45 44 1,000 2,533E-03 0,07294793 ! regulation of actin cytoskeleton organization GO:0032956 46 45 1,000 2,648E-03 0,07509356 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 1,000 2,648E-03 0,07395578 ! regulation of actin filament-based process GO:0032970 47 46 1,000 2,766E-03 0,07608964 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 1,000 2,766E-03 0,07497067 ! positive regulation of ligase activity GO:0051351 47 46 1,000 2,766E-03 0,07388414 ! cellular response to hormone stimulus GO:0032870 48 46 1,000 2,766E-03 0,07282865 ! actin filament organization GO:0007015 50 48 1,000 3,009E-03 0,07810321 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 1,000 3,009E-03 0,07701845 ! regulation of ligase activity GO:0051340 50 49 1,000 3,134E-03 0,07911917 ! skeletal muscle tissue development GO:0007519 50 49 1,000 3,134E-03 0,07804999 GO:0060538|skeletal muscle organ development, ! regulation of binding GO:0051098 60 57 1,000 4,22E-03 0,10370555 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 1,000 4,667E-03 0,11316903 ! cellular respiration GO:0045333 62 61 1,000 4,82E-03 0,11537387 ! proteasomal protein catabolic process GO:0010498 62 61 1,000 4,82E-03 0,11389472 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! regulation of cellular component biogenesis GO:0044087 63 62 1,000 4,976E-03 0,11608891 ! negative regulation of cellular component organization GO:0051129 65 63 1,000 5,134E-03 0,11828175 ! regulation of cytoskeleton organization GO:0051493 66 64 1,000 5,295E-03 0,12047314 ! negative regulation of protein metabolic process GO:0051248 66 66 1,000 5,623E-03 0,12637367 ! muscle contraction GO:0006936 67 67 1,000 5,79E-03 0,12856804 ! striated muscle tissue development GO:0014706 69 67 1,000 5,79E-03 0,12703747 ! regulation of cell size GO:0008361 68 68 1,000 5,96E-03 0,12922198 ! muscle tissue development GO:0060537 72 70 1,000 6,306E-03 0,1351384 ! negative regulation of signal transduction GO:0009968 71 71 1,000 6,482E-03 0,13732402 ! muscle system process GO:0003012 72 72 1,000 6,661E-03 0,13950726 ! positive regulation of hydrolase activity GO:0051345 72 72 1,000 6,661E-03 0,13793976 ! negative regulation of cell communication GO:0010648 76 76 1,000 7,399E-03 0,15150889 ! rRNA transcription GO:0009303 5 5 0,000 8,693E-03 0,17605875 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 8,693E-03 0,17414507 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 8,693E-03 0,17227254 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 8,693E-03 0,17043986 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 8,693E-03 0,16864575 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 8,693E-03 0,16688903 ! reproductive cellular process GO:0048610 5 5 0,000 8,693E-03 0,16516852 ! positive regulation of glucose metabolic process GO:0010907 5 5 0,000 8,693E-03 0,16348313 ! negative regulation of blood pressure GO:0045776 6 5 0,000 8,693E-03 0,16183178 ! prostate gland development GO:0030850 5 5 0,000 8,693E-03 0,16021346 ! metencephalon development GO:0022037 5 5 0,000 8,693E-03 0,15862719 ! water transport GO:0006833 5 5 0,000 8,693E-03 0,15707202 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 8,693E-03 0,15554705 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 8,693E-03 0,15405141 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 8,693E-03 0,15258425 ! glycerol metabolic process GO:0006071 5 5 0,000 8,693E-03 0,15114478 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 8,693E-03 0,14973221 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 8,693E-03 0,1483458 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 8,693E-03 0,14698483 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 8,693E-03 0,1456486 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 8,693E-03 0,14433645 ! filopodium assembly GO:0046847 7 5 0,000 8,693E-03 0,14304774 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 8,693E-03 0,14178183 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 8,693E-03 0,14053813 ! GTP metabolic process GO:0046039 5 5 0,000 8,693E-03 0,13931606 ! establishment of tissue polarity GO:0007164 5 5 0,000 8,693E-03 0,13811506 ! mRNA stabilization GO:0048255 5 5 0,000 8,693E-03 0,13693459 GO:0043489|RNA stabilization, ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 8,693E-03 0,13577412 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 8,693E-03 0,13463316 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 8,693E-03 0,13351122 ! social behavior GO:0035176 5 5 0,000 8,693E-03 0,13240782 ! macrophage chemotaxis GO:0048246 6 5 0,000 8,693E-03 0,13132251 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 8,693E-03 0,13025485 ! memory GO:0007613 5 5 0,000 8,693E-03 0,12920441 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 8,693E-03 0,12817077 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 8,693E-03 0,12715354 ! membrane hyperpolarization GO:0060081 5 5 0,000 8,693E-03 0,12615233 ! response to lipid GO:0033993 5 5 0,000 8,693E-03 0,12516677 ! erythrocyte maturation GO:0043249 5 5 0,000 8,693E-03 0,12419648 ! hippocampus development GO:0021766 6 5 0,000 8,693E-03 0,12324113 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 8,693E-03 0,12230035 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 8,693E-03 0,12137384 ! middle ear morphogenesis GO:0042474 5 5 0,000 8,693E-03 0,12046125 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 8,693E-03 0,11956229 ! mechanosensory behavior GO:0007638 5 5 0,000 8,693E-03 0,11867664 ! heart looping GO:0001947 5 5 0,000 8,693E-03 0,11780402 ! negative regulation of endocytosis GO:0045806 5 5 0,000 8,693E-03 0,11694413 ! response to interferon-gamma GO:0034341 5 5 0,000 8,693E-03 0,11609671 ! pseudouridine synthesis GO:0001522 5 5 0,000 8,693E-03 0,11526149 ! endocrine pancreas development GO:0031018 5 5 0,000 8,693E-03 0,11443819 ! pH reduction GO:0045851 5 5 0,000 8,693E-03 0,11362657 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 8,693E-03 0,11282638 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 8,693E-03 0,11203739 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 8,693E-03 0,11125935 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 8,693E-03 0,11049204 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 8,693E-03 0,10973525 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 8,693E-03 0,10898875 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 8,693E-03 0,10825234 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 8,693E-03 0,10752582 ! adrenal gland development GO:0030325 5 5 0,000 8,693E-03 0,10680898 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 8,693E-03 0,10610163 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 8,693E-03 0,1054036 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 8,693E-03 0,10471468 ! astrocyte differentiation GO:0048708 5 5 0,000 8,693E-03 0,10403472 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 8,693E-03 0,10336353 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 8,693E-03 0,10270094 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 8,693E-03 0,10204679 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 8,693E-03 0,10140093 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 8,693E-03 0,10076319 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 8,693E-03 0,10013342 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 8,693E-03 0,09951147 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 8,693E-03 0,0988972 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 8,693E-03 0,09829047 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 8,693E-03 0,09769114 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 8,693E-03 0,09709907 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 8,693E-03 0,09651414 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 8,693E-03 0,09593621 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 8,693E-03 0,09536516 ! response to ATP GO:0033198 5 5 0,000 8,693E-03 0,09480087 ! regulation of type I interferon production GO:0032479 5 5 0,000 8,693E-03 0,09424321 ! regulation of appetite GO:0032098 5 5 0,000 8,693E-03 0,09369208 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 8,693E-03 0,09314736 ! paraxial mesoderm development GO:0048339 5 5 0,000 8,693E-03 0,09260894 ! regulation of phospholipase A2 activity GO:0032429 5 5 0,000 8,693E-03 0,0920767 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 8,693E-03 0,09155055 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 8,693E-03 0,09103038 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 8,693E-03 0,09051608 ! receptor clustering GO:0043113 5 5 0,000 8,693E-03 0,09000756 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 8,693E-03 0,08950473 ! fear response GO:0042596 5 5 0,000 8,693E-03 0,08900748 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 8,693E-03 0,08851573 ! lens development in camera-type eye GO:0002088 5 5 0,000 8,693E-03 0,08802938 ! retinol metabolic process GO:0042572 5 5 0,000 8,693E-03 0,08754834 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 8,693E-03 0,08707254 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 8,693E-03 0,08660187 ! positive regulation of exocytosis GO:0045921 6 5 0,000 8,693E-03 0,08613627 ! parturition GO:0007567 5 5 0,000 8,693E-03 0,08567565 ! cellular glucose homeostasis GO:0001678 5 5 0,000 8,693E-03 0,08521993 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 8,693E-03 0,08476903 ! Schwann cell differentiation GO:0014037 5 5 0,000 8,693E-03 0,08432288 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 8,693E-03 0,0838814 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 8,693E-03 0,08344451 ! protein heterooligomerization GO:0051291 5 5 0,000 8,693E-03 0,08301216 ! regulation of gliogenesis GO:0014013 5 5 0,000 8,693E-03 0,08258426 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 8,693E-03 0,08216075 ! response to UV-B GO:0010224 5 5 0,000 8,693E-03 0,08174156 ! oligodendrocyte development GO:0014003 5 5 0,000 8,693E-03 0,08132663 ! hyaluronan metabolic process GO:0030212 5 5 0,000 8,693E-03 0,08091589 ! activated T cell proliferation GO:0050798 5 5 0,000 8,693E-03 0,08050928 ! interaction with symbiont GO:0051702 5 5 0,000 8,693E-03 0,08010673 ! cellular extravasation GO:0045123 5 5 0,000 8,693E-03 0,07970819 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 8,693E-03 0,0793136 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 8,693E-03 0,07892289 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 8,693E-03 0,07853601 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 8,693E-03 0,07815291 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 8,693E-03 0,07777353 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 8,693E-03 0,07739781 ! response to amine stimulus GO:0014075 5 5 0,000 8,693E-03 0,0770257 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 8,693E-03 0,07665716 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 8,693E-03 0,07629213 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 8,693E-03 0,07593055 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 8,693E-03 0,07557239 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 8,693E-03 0,07521759 ! neuron recognition GO:0008038 5 5 0,000 8,693E-03 0,0748661 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 8,693E-03 0,07451789 ! decidualization GO:0046697 5 5 0,000 8,693E-03 0,0741729 ! hair follicle maturation GO:0048820 5 5 0,000 8,693E-03 0,07383109 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 8,693E-03 0,07349241 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 8,693E-03 0,07315683 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 8,693E-03 0,0728243 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 8,693E-03 0,07249478 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 8,693E-03 0,07216823 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 8,693E-03 0,0718446 ! postreplication repair GO:0006301 5 5 0,000 8,693E-03 0,07152387 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 8,693E-03 0,07120598 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 8,693E-03 0,07089091 ! histone methylation GO:0016571 5 5 0,000 8,693E-03 0,07057862 ! DNA methylation GO:0006306 5 5 0,000 8,693E-03 0,07026906 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 8,693E-03 0,06996221 ! T cell lineage commitment GO:0002360 5 5 0,000 8,693E-03 0,06965803 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 8,693E-03 0,06935648 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 8,693E-03 0,06905753 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 8,693E-03 0,06876114 ! intracellular cholesterol transport GO:0032367 5 5 0,000 8,693E-03 0,06846729 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 8,693E-03 0,06817594 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 8,693E-03 0,06788706 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 8,693E-03 0,06760062 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 8,693E-03 0,06731658 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 8,693E-03 0,06703492 ! sterol catabolic process GO:0016127 5 5 0,000 8,693E-03 0,06675561 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 8,693E-03 0,06647862 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 8,693E-03 0,06620391 ! detection of biotic stimulus GO:0009595 5 5 0,000 8,693E-03 0,06593147 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 8,693E-03 0,06566126 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 8,693E-03 0,06539325 ! zymogen activation GO:0031638 5 5 0,000 8,693E-03 0,06512742 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 8,693E-03 0,06486375 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 8,693E-03 0,0646022 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 8,693E-03 0,06434276 ! peptidyl-lysine modification GO:0018205 5 5 0,000 8,693E-03 0,06408539 ! negative regulation of neuroblast proliferation GO:0007406 5 5 0,000 8,693E-03 0,06383007 ! peptidyl-histidine modification GO:0018202 5 5 0,000 8,693E-03 0,06357677 ! nucleosome positioning GO:0016584 5 5 0,000 8,693E-03 0,06332548 ! regulation of isotype switching GO:0045191 5 5 0,000 8,693E-03 0,06307617 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 8,693E-03 0,06282881 ! negative regulation of neurological system process GO:0031645 5 5 0,000 8,693E-03 0,06258338 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 8,693E-03 0,06233987 ! glutathione biosynthetic process GO:0006750 5 5 0,000 8,693E-03 0,06209824 ! NADPH regeneration GO:0006740 5 5 0,000 8,693E-03 0,06185848 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 8,693E-03 0,06162056 ! positive regulation of epidermis development GO:0045684 5 5 0,000 8,693E-03 0,06138447 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 8,693E-03 0,06115018 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 8,693E-03 0,06091767 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 8,693E-03 0,06068692 ! sarcomere organization GO:0045214 5 5 0,000 8,693E-03 0,06045791 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 8,693E-03 0,06023063 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 8,693E-03 0,06000504 ! negative regulation of glucose transport GO:0010829 5 5 0,000 8,693E-03 0,05978114 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 8,693E-03 0,05955891 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 8,693E-03 0,05933832 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 8,693E-03 0,05911936 ! spleen development GO:0048536 5 5 0,000 8,693E-03 0,05890201 ! male genitalia development GO:0030539 5 5 0,000 8,693E-03 0,05868625 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 8,693E-03 0,05847207 ! quaternary ammonium group transport GO:0015697 5 5 0,000 8,693E-03 0,05825944 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 8,693E-03 0,05804836 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 8,693E-03 0,0578388 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 8,693E-03 0,05763074 ! removal of superoxide radicals GO:0019430 6 5 0,000 8,693E-03 0,05742418 ! myeloid cell homeostasis GO:0002262 5 5 0,000 8,693E-03 0,05721909 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 8,693E-03 0,05701547 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 8,693E-03 0,05681329 ! ATP catabolic process GO:0006200 5 5 0,000 8,693E-03 0,05661253 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 8,693E-03 0,05641319 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 8,693E-03 0,05621525 ! blastocyst formation GO:0001825 5 5 0,000 8,693E-03 0,05601869 ! regulation of fibrinolysis GO:0051917 5 5 0,000 8,693E-03 0,05582351 ! embryonic gut development GO:0048566 5 5 0,000 8,693E-03 0,05562968 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 8,693E-03 0,05543718 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 8,693E-03 0,05524602 ! activation of innate immune response GO:0002218 5 5 0,000 8,693E-03 0,05505617 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 8,693E-03 0,05486762 ! catecholamine transport GO:0051937 5 5 0,000 8,693E-03 0,05468036 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 8,693E-03 0,05449438 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 8,693E-03 0,05430965 ! muscle adaptation GO:0043500 5 5 0,000 8,693E-03 0,05412617 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 8,693E-03 0,05394393 ! embryonic heart tube development GO:0035050 5 5 0,000 8,693E-03 0,05376291 ! cardiac cell differentiation GO:0035051 6 5 0,000 8,693E-03 0,0535831 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 8,693E-03 0,05340449 ! defense response to fungus GO:0050832 5 5 0,000 8,693E-03 0,05322706 ! lysogeny GO:0030069 5 5 0,000 8,693E-03 0,05305082 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 8,693E-03 0,05287573 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 8,693E-03 0,0527018 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 8,693E-03 0,052529 ! response to nicotine GO:0035094 5 5 0,000 8,693E-03 0,05235734 ! establishment of cell polarity GO:0030010 5 5 0,000 8,693E-03 0,0521868 ! mitochondrion localization GO:0051646 5 5 0,000 8,693E-03 0,05201736 ! nucleus localization GO:0051647 5 5 0,000 8,693E-03 0,05184902 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 8,693E-03 0,05168176 ! heart development GO:0007507 90 87 1,000 9,609E-03 0,0569424 ! chemotaxis GO:0006935 90 89 1,000 0,01003886 0,05930008 GO:0042330|taxis, ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 0,01042336 0,06137462 ! axon extension GO:0048675 7 6 0,000 0,01042336 0,06117915 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,01042336 0,06098494 ! N-terminal protein amino acid modification GO:0031365 6 6 0,000 0,01042336 0,06079195 GO:0018409|peptide or protein amino-terminal blocking, ! tRNA modification GO:0006400 6 6 0,000 0,01042336 0,06060017 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,01042336 0,06040961 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,01042336 0,06022023 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,01042336 0,06003205 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,01042336 0,05984503 ! virus-host interaction GO:0019048 6 6 0,000 0,01042336 0,05965918 ! regulation of S phase GO:0033261 6 6 0,000 0,01042336 0,05947447 ! myotube differentiation GO:0014902 6 6 0,000 0,01042336 0,05929091 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,01042336 0,05910848 ! bone remodeling GO:0046849 6 6 0,000 0,01042336 0,05892716 ! N-glycan processing GO:0006491 6 6 0,000 0,01042336 0,05874696 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 0,01042336 0,05856785 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,01042336 0,05838983 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,01042336 0,05821289 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,01042336 0,05803702 ! RNA methylation GO:0001510 6 6 0,000 0,01042336 0,05786221 ! cartilage condensation GO:0001502 7 6 0,000 0,01042336 0,05768845 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,01042336 0,05751573 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 0,01042336 0,05734404 GO:0050927|positive regulation of positive chemotaxis, ! succinate metabolic process GO:0006105 7 6 0,000 0,01042336 0,05717338 ! artery development GO:0060840 6 6 0,000 0,01042336 0,05700372 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,01042336 0,05683507 ! bile acid metabolic process GO:0008206 6 6 0,000 0,01042336 0,05666742 ! androgen metabolic process GO:0008209 6 6 0,000 0,01042336 0,05650075 ! estrogen metabolic process GO:0008210 6 6 0,000 0,01042336 0,05633506 ! limbic system development GO:0021761 7 6 0,000 0,01042336 0,05617034 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,01042336 0,05600657 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 0,000 0,01042336 0,05584376 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,01042336 0,0556819 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,01042336 0,05552097 ! pathogenesis GO:0009405 6 6 0,000 0,01042336 0,05536096 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,01042336 0,05520188 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,01042336 0,05504371 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,01042336 0,05488644 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,01042336 0,05473007 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,01042336 0,05457459 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,01042336 0,05441998 ! arginine metabolic process GO:0006525 6 6 0,000 0,01042336 0,05426626 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,01042336 0,05411339 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,01042336 0,05396139 ! glutamate catabolic process GO:0006538 7 6 0,000 0,01042336 0,05381024 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,01042336 0,05365993 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,01042336 0,05351046 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,01042336 0,05336182 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,01042336 0,053214 ! ER overload response GO:0006983 6 6 0,000 0,01042336 0,053067 ! V(D)J recombination GO:0033151 6 6 0,000 0,01042336 0,05292081 ! focal adhesion formation GO:0048041 7 6 0,000 0,01042336 0,05277542 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,01042336 0,05263083 ! negative regulation of T cell proliferation GO:0042130 6 6 0,000 0,01042336 0,05248703 GO:0070667|negative regulation of mast cell proliferation, ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,01042336 0,05234402 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,01042336 0,05220178 ! regulation of heart rate GO:0002027 6 6 0,000 0,01042336 0,05206031 ! lipid digestion GO:0044241 6 6 0,000 0,01042336 0,05191961 ! asymmetric protein localization GO:0008105 6 6 0,000 0,01042336 0,05177966 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,01042336 0,05164047 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,01042336 0,05150202 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,01042336 0,05136432 ! regulation of vascular permeability GO:0043114 6 6 0,000 0,01042336 0,05122735 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,01042336 0,0510911 ! ruffle organization GO:0031529 6 6 0,000 0,01042336 0,05095558 ! peptidyl-serine phosphorylation GO:0018105 6 6 0,000 0,01042336 0,05082078 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,01042336 0,05068669 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,01042336 0,0505533 ! neutral amino acid transport GO:0015804 6 6 0,000 0,01042336 0,05042062 ! L-amino acid transport GO:0015807 6 6 0,000 0,01042336 0,05028862 ! bone mineralization GO:0030282 6 6 0,000 0,01042336 0,05015732 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,01042336 0,0500267 ! negative regulation of ossification GO:0030279 6 6 0,000 0,01042336 0,04989677 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,01042336 0,0497675 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of bone resorption GO:0045124 6 6 0,000 0,01042336 0,0496389 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,01042336 0,04951097 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,01042336 0,04938369 ! G1 DNA damage checkpoint GO:0031571 6 6 0,000 0,01042336 0,04925706 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,01042336 0,04913109 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,01042336 0,04900575 ! regulation of organ growth GO:0046620 6 6 0,000 0,01042336 0,04888106 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,01042336 0,04875699 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,01042336 0,04863356 ! response to dsRNA GO:0043331 6 6 0,000 0,01042336 0,04851074 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,01042336 0,04838855 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,01042336 0,04826697 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! regulation of T cell differentiation in the thymus GO:0033081 6 6 0,000 0,01042336 0,048146 ! genitalia development GO:0048806 6 6 0,000 0,01042336 0,04802564 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,01042336 0,04790587 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,01042336 0,0477867 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 0,000 0,01042336 0,04766813 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,01042336 0,04755014 ! multicellular organismal aging GO:0010259 6 6 0,000 0,01042336 0,04743273 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,01042336 0,0473159 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,01042336 0,04719964 ! erythrocyte development GO:0048821 6 6 0,000 0,01042336 0,04708396 ! renal water homeostasis GO:0003091 6 6 0,000 0,01042336 0,04696884 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,01042336 0,04685428 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,01042336 0,04674028 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,01042336 0,04662683 ! ribosome assembly GO:0042255 6 6 0,000 0,01042336 0,04651393 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,01042336 0,04640158 ! diencephalon development GO:0021536 6 6 0,000 0,01042336 0,04628977 ! fucose catabolic process GO:0019317 6 6 0,000 0,01042336 0,0461785 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,01042336 0,04606776 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 0,01042336 0,04595755 ! regulation of lipid transport GO:0032368 6 6 0,000 0,01042336 0,04584786 ! regulation of cell division GO:0051302 6 6 0,000 0,01042336 0,0457387 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,01042336 0,04563006 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,01042336 0,04552193 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,01042336 0,04541431 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,01042336 0,0453072 ! neuroblast proliferation GO:0007405 6 6 0,000 0,01042336 0,0452006 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,01042336 0,04509449 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,01042336 0,04498889 ! regulation of glucose transport GO:0010827 6 6 0,000 0,01042336 0,04488377 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,01042336 0,04477915 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,01042336 0,04467501 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,01042336 0,04457136 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,01042336 0,04446818 ! thymus development GO:0048538 6 6 0,000 0,01042336 0,04436548 ! lymph node development GO:0048535 6 6 0,000 0,01042336 0,04426326 ! organic cation transport GO:0015695 6 6 0,000 0,01042336 0,0441615 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,01042336 0,04406022 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,01042336 0,04395939 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 0,000 0,01042336 0,04385903 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,01042336 0,04375912 ! sperm-egg recognition GO:0035036 7 6 0,000 0,01042336 0,04365967 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,01042336 0,04356067 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,01042336 0,04346211 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,01042336 0,04336401 ! alditol metabolic process GO:0019400 6 6 0,000 0,01042336 0,04326634 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,01042336 0,04316911 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,01042336 0,04307232 ! maternal placenta development GO:0001893 6 6 0,000 0,01042336 0,04297596 ! regulation of embryonic development GO:0045995 6 6 0,000 0,01042336 0,04288003 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,01042336 0,04278453 ! localization within membrane GO:0051668 6 6 0,000 0,01042336 0,04268945 ! negative regulation of cell cycle GO:0045786 92 91 1,000 0,01047743 0,04281573 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 1,000 0,01069989 0,04362809 ! epidermis development GO:0008544 94 94 1,000 0,01115115 0,04536771 ! regulation of cell growth GO:0001558 97 96 1,000 0,01161081 0,04713376 ! respiratory burst GO:0045730 7 7 0,000 0,01215087 0,04921771 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,01215087 0,04910978 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,01215087 0,04900232 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,01215087 0,04889533 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,01215087 0,0487888 ! positive regulation of cellular catabolic process GO:0031331 7 7 0,000 0,01215087 0,04868274 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,01215087 0,04857714 ! regulation of chemokine production GO:0032642 7 7 0,000 0,01215087 0,04847199 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,01215087 0,0483673 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,01215087 0,04826306 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,01215087 0,04815927 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,01215087 0,04805592 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,01215087 0,04795302 ! gene silencing by RNA GO:0031047 7 7 0,000 0,01215087 0,04785056 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,01215087 0,04774853 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,01215087 0,04764694 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,01215087 0,04754577 ! axis specification GO:0009798 7 7 0,000 0,01215087 0,04744504 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,01215087 0,04734474 ! visual behavior GO:0007632 7 7 0,000 0,01215087 0,04724485 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,01215087 0,04714539 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,01215087 0,04704634 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,01215087 0,04694771 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,01215087 0,0468495 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,01215087 0,04675169 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,01215087 0,04665429 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,01215087 0,0465573 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,01215087 0,04646071 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,01215087 0,04636451 ! digestive system development GO:0055123 7 7 0,000 0,01215087 0,04626872 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,01215087 0,04617332 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,01215087 0,04607831 ! protein targeting to ER GO:0045047 8 7 0,000 0,01215087 0,0459837 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,01215087 0,04588947 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,01215087 0,04579562 ! endoderm development GO:0007492 7 7 0,000 0,01215087 0,04570216 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,01215087 0,04560908 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,01215087 0,04551638 GO:0006688|glycosphingolipid biosynthetic process, ! regulation of mRNA processing GO:0050684 7 7 0,000 0,01215087 0,04542406 ! response to hexose stimulus GO:0009746 7 7 0,000 0,01215087 0,0453321 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,01215087 0,04524052 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,01215087 0,04514931 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,01215087 0,04505847 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 0,000 0,01215087 0,04496799 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,01215087 0,04487788 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,01215087 0,04478812 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,01215087 0,04469872 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,01215087 0,04460968 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,01215087 0,04452099 ! response to X-ray GO:0010165 7 7 0,000 0,01215087 0,04443266 ! regulation of intracellular pH GO:0051453 7 7 0,000 0,01215087 0,04434467 ! UV protection GO:0009650 7 7 0,000 0,01215087 0,04425704 ! DNA integration GO:0015074 7 7 0,000 0,01215087 0,04416974 ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 0,000 0,01215087 0,04408279 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,01215087 0,04399619 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,01215087 0,04390992 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,01215087 0,04382399 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,01215087 0,0437384 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,01215087 0,04365314 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,01215087 0,04356821 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,01215087 0,04348361 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,01215087 0,04339934 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,01215087 0,0433154 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,01215087 0,04323178 ! axon cargo transport GO:0008088 7 7 0,000 0,01215087 0,04314848 ! eating behavior GO:0042755 7 7 0,000 0,01215087 0,0430655 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,01215087 0,04298284 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,01215087 0,0429005 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,01215087 0,04281847 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,01215087 0,04273676 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,01215087 0,04265535 ! cranial nerve development GO:0021545 7 7 0,000 0,01215087 0,04257426 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,01215087 0,04249347 ! induction of an organ GO:0001759 7 7 0,000 0,01215087 0,04241299 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,01215087 0,04233282 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,01215087 0,04225294 ! autonomic nervous system development GO:0048483 7 7 0,000 0,01215087 0,04217337 ! intracellular lipid transport GO:0032365 7 7 0,000 0,01215087 0,0420941 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,01215087 0,04201512 ! platelet activation GO:0030168 8 7 0,000 0,01215087 0,04193644 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,01215087 0,04185806 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,01215087 0,04177996 ! natural killer cell activation GO:0030101 7 7 0,000 0,01215087 0,04170216 ! response to gamma radiation GO:0010332 8 7 0,000 0,01215087 0,04162465 ! NADP metabolic process GO:0006739 7 7 0,000 0,01215087 0,04154742 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,01215087 0,04147048 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,01215087 0,04139383 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,01215087 0,04131745 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,01215087 0,04124136 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,01215087 0,04116555 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,01215087 0,04109002 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,01215087 0,04101476 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,01215087 0,04093978 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,01215087 0,04086507 ! cell-cell recognition GO:0009988 8 7 0,000 0,01215087 0,04079064 ! hormone catabolic process GO:0042447 7 7 0,000 0,01215087 0,04071647 ! dopamine metabolic process GO:0042417 7 7 0,000 0,01215087 0,04064258 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,01215087 0,04056895 ! oxygen transport GO:0015671 7 7 0,000 0,01215087 0,04049559 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,01215087 0,04042249 ! regulation of mRNA stability GO:0043488 7 7 0,000 0,01215087 0,04034966 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,01215087 0,04027709 ! regulation of axon extension GO:0030516 7 7 0,000 0,01215087 0,04020478 ! cell killing GO:0001906 7 7 0,000 0,01215087 0,04013272 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,01215087 0,04006093 ! adult feeding behavior GO:0008343 7 7 0,000 0,01215087 0,03998939 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,01215087 0,03991811 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,01215087 0,03984708 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,01215087 0,03977631 ! negative regulation of T cell activation GO:0050868 7 7 0,000 0,01215087 0,03970578 ! response to cold GO:0009409 7 7 0,000 0,01215087 0,0396355 ! anti-apoptosis GO:0006916 100 99 1,000 0,01231594 0,04010295 ! ectoderm development GO:0007398 99 99 1,000 0,01231594 0,04003222 ! response to hormone stimulus GO:0009725 102 100 1,000 0,01255512 0,04073782 ! muscle organ development GO:0007517 102 100 1,000 0,01255512 0,04066623 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,01387562 0,04486451 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,01387562 0,04478594 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,01387562 0,04470764 ! positive regulation of translation GO:0045727 8 8 0,000 0,01387562 0,04462962 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,01387562 0,04455186 ! superoxide anion generation GO:0042554 8 8 0,000 0,01387562 0,04447438 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,01387562 0,04439717 ! cGMP metabolic process GO:0046068 8 8 0,000 0,01387562 0,04432022 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,01387562 0,04424355 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,01387562 0,04416713 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,01387562 0,04409098 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,01387562 0,04401509 ! negative regulation of bone remodeling GO:0046851 8 8 0,000 0,01387562 0,04393947 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,01387562 0,0438641 ! zinc ion transport GO:0006829 8 8 0,000 0,01387562 0,04378899 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,01387562 0,04371414 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,01387562 0,04363954 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,01387562 0,0435652 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,01387562 0,0434911 ! lipid localization GO:0010876 8 8 0,000 0,01387562 0,04341727 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,01387562 0,04334368 ! response to cAMP GO:0051591 8 8 0,000 0,01387562 0,04327034 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,01387562 0,04319725 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,01387562 0,0431244 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,01387562 0,0430518 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,01387562 0,04297944 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,01387562 0,04290733 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,01387562 0,04283546 ! sensory perception of taste GO:0050909 8 8 0,000 0,01387562 0,04276383 ! organelle fusion GO:0048284 8 8 0,000 0,01387562 0,04269244 ! pancreas development GO:0031016 8 8 0,000 0,01387562 0,04262128 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,01387562 0,04255037 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,01387562 0,04247968 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,01387562 0,04240924 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,01387562 0,04233902 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,01387562 0,04226904 ! sperm motility GO:0030317 8 8 0,000 0,01387562 0,04219929 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,01387562 0,04212977 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,01387562 0,04206048 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,01387562 0,04199141 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,01387562 0,04192257 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,01387562 0,04185396 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,01387562 0,04178557 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,01387562 0,04171741 ! Golgi organization GO:0007030 8 8 0,000 0,01387562 0,04164946 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,01387562 0,04158174 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,01387562 0,04151424 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 0,01387562 0,04144695 ! fructose metabolic process GO:0006000 8 8 0,000 0,01387562 0,04137989 ! mannose metabolic process GO:0006013 9 8 0,000 0,01387562 0,04131304 ! NAD metabolic process GO:0019674 8 8 0,000 0,01387562 0,0412464 ! sex determination GO:0007530 8 8 0,000 0,01387562 0,04117998 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,01387562 0,04111378 ! plasma membrane fusion GO:0045026 8 8 0,000 0,01387562 0,04104778 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 0,000 0,01387562 0,040982 ! response to fungus GO:0009620 8 8 0,000 0,01387562 0,04091643 ! stem cell differentiation GO:0048863 8 8 0,000 0,01387562 0,04085107 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,01387562 0,04078592 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,01387562 0,04072097 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,01387562 0,04065623 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,01387562 0,0405917 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,01387562 0,04052737 ! regulation of vasodilation GO:0042312 8 8 0,000 0,01387562 0,04046324 ! vasoconstriction GO:0042310 8 8 0,000 0,01387562 0,04039932 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,01387562 0,0403356 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,01387562 0,04027208 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,01387562 0,04020876 ! sensory perception of pain GO:0019233 8 8 0,000 0,01387562 0,04014563 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,01387562 0,04008271 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,01387562 0,04001998 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,01387562 0,03995745 ! chromatin silencing GO:0006342 8 8 0,000 0,01387562 0,03989512 ! tissue regeneration GO:0042246 8 8 0,000 0,01387562 0,03983297 ! salivary gland development GO:0007431 8 8 0,000 0,01387562 0,03977103 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,01387562 0,03970927 ! T cell homeostasis GO:0043029 8 8 0,000 0,01387562 0,0396477 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,01387562 0,03958633 ! peptidyl-serine modification GO:0018209 8 8 0,000 0,01387562 0,03952515 ! water homeostasis GO:0030104 8 8 0,000 0,01387562 0,03946415 ! cofactor transport GO:0051181 8 8 0,000 0,01387562 0,03940334 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,01387562 0,03934272 ! acid secretion GO:0046717 8 8 0,000 0,01387562 0,03928229 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 0,01387562 0,03922204 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,01387562 0,03916197 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,01387562 0,03910209 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,01387562 0,0390424 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,01387562 0,03898288 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,01387562 0,03892355 ! regulation of RNA stability GO:0043487 8 8 0,000 0,01387562 0,03886439 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,01387562 0,03880542 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 0,000 0,01387562 0,03874662 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,01387562 0,038688 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,01387562 0,03862956 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,01387562 0,0385713 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,01387562 0,03851321 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,01387562 0,03845529 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,01387562 0,03839755 ! developmental induction GO:0031128 8 8 0,000 0,01387562 0,03833998 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,01387562 0,03828259 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,01387562 0,03822537 ! actin filament polymerization GO:0030041 9 8 0,000 0,01387562 0,03816831 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 0,01387562 0,03811143 ! peptide hormone processing GO:0016486 8 8 0,000 0,01387562 0,03805472 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,01387562 0,03799817 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,01387562 0,03794179 ! lactation GO:0007595 10 9 0,000 0,01559761 0,04258725 ! embryonic pattern specification GO:0009880 10 9 0,000 0,01559761 0,04252425 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,01559761 0,04246143 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,01559761 0,04239881 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,01559761 0,04233636 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,01559761 0,0422741 ! negative regulation of cell cycle process GO:0010948 9 9 0,000 0,01559761 0,04221203 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 0,000 0,01559761 0,04215013 ! viral genome replication GO:0019079 9 9 0,000 0,01559761 0,04208842 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,01559761 0,04202689 ! copper ion transport GO:0006825 9 9 0,000 0,01559761 0,04196553 ! lipid phosphorylation GO:0046834 9 9 0,000 0,01559761 0,04190436 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,01559761 0,04184336 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,01559761 0,04178254 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,01559761 0,0417219 ! RNA polyadenylation GO:0043631 9 9 0,000 0,01559761 0,04166144 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,01559761 0,04160114 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,01559761 0,04154103 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,01559761 0,04148108 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,01559761 0,04142131 ! phospholipid efflux GO:0033700 9 9 0,000 0,01559761 0,04136171 ! response to alkaloid GO:0043279 10 9 0,000 0,01559761 0,04130229 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,01559761 0,04124303 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,01559761 0,04118394 GO:0042107|cytokine metabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 9 9 0,000 0,01559761 0,04112502 ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,01559761 0,04106627 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,01559761 0,04100769 ! response to ethanol GO:0045471 9 9 0,000 0,01559761 0,04094927 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 0,000 0,01559761 0,04089103 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,01559761 0,04083294 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,01559761 0,04077502 ! methionine metabolic process GO:0006555 9 9 0,000 0,01559761 0,04071727 ! glutamine metabolic process GO:0006541 9 9 0,000 0,01559761 0,04065968 ! cerebral cortex development GO:0021987 9 9 0,000 0,01559761 0,04060225 ! response to osmotic stress GO:0006970 9 9 0,000 0,01559761 0,04054498 ! pigmentation during development GO:0048066 9 9 0,000 0,01559761 0,04048787 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,01559761 0,04043093 ! central nervous system neuron development GO:0021954 10 9 0,000 0,01559761 0,04037414 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,01559761 0,04031752 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,01559761 0,04026105 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,01559761 0,04020474 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,01559761 0,04014859 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,01559761 0,0400926 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,01559761 0,04003676 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,01559761 0,03998107 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,01559761 0,03992554 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,01559761 0,03987017 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,01559761 0,03981495 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,01559761 0,03975988 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,01559761 0,03970496 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,01559761 0,03965019 ! positive regulation of protein import into nucleus GO:0042307 9 9 0,000 0,01559761 0,03959558 ! DNA replication initiation GO:0006270 9 9 0,000 0,01559761 0,03954112 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,01559761 0,0394868 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,01559761 0,03943264 ! regulation of cellular pH GO:0030641 9 9 0,000 0,01559761 0,03937862 ! histone acetylation GO:0016573 9 9 0,000 0,01559761 0,03932475 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,01559761 0,03927103 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,01559761 0,03921745 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,01559761 0,03916402 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,01559761 0,03911074 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,01559761 0,0390576 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,01559761 0,0390046 ! negative regulation of tissue remodeling GO:0034104 9 9 0,000 0,01559761 0,03895175 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,01559761 0,03889904 ! regulation of leukocyte migration GO:0002685 9 9 0,000 0,01559761 0,03884647 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,01559761 0,03879405 ! collagen catabolic process GO:0030574 9 9 0,000 0,01559761 0,03874177 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,01559761 0,03868962 ! purine base metabolic process GO:0006144 9 9 0,000 0,01559761 0,03863762 ! gas transport GO:0015669 9 9 0,000 0,01559761 0,03858576 ! cholesterol efflux GO:0033344 9 9 0,000 0,01559761 0,03853404 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,01559761 0,03848245 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,01559761 0,038431 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,01559761 0,03837969 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,01559761 0,03832852 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 0,000 0,01559761 0,03827748 ! defense response to virus GO:0051607 9 9 0,000 0,01559761 0,03822658 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,01559761 0,03817582 ! actin filament-based movement GO:0030048 9 9 0,000 0,01559761 0,03812519 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,01559761 0,03807469 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,01731684 0,04221552 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,01731684 0,04215975 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,01731684 0,04210413 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,01731684 0,04204866 ! regulation of glucose metabolic process GO:0010906 10 10 0,000 0,01731684 0,04199333 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,01731684 0,04193815 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,01731684 0,04188311 ! neuron maturation GO:0042551 10 10 0,000 0,01731684 0,04182822 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,01731684 0,04177347 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,01731684 0,04171886 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,01731684 0,0416644 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,01731684 0,04161008 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,01731684 0,0415559 ! hormone secretion GO:0046879 10 10 0,000 0,01731684 0,04150186 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,01731684 0,04144796 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,01731684 0,0413942 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 0,000 0,01731684 0,04134059 ! inositol metabolic process GO:0006020 10 10 0,000 0,01731684 0,0412871 ! cAMP metabolic process GO:0046058 10 10 0,000 0,01731684 0,04123376 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,01731684 0,04118056 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,01731684 0,04112749 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,01731684 0,04107456 ! glial cell development GO:0021782 10 10 0,000 0,01731684 0,04102176 ! phototransduction GO:0007602 11 10 0,000 0,01731684 0,0409691 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,01731684 0,04091658 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,01731684 0,04086419 ! fat cell differentiation GO:0045444 10 10 0,000 0,01731684 0,04081193 ! myoblast differentiation GO:0045445 10 10 0,000 0,01731684 0,04075981 ! centrosome cycle GO:0007098 10 10 0,000 0,01731684 0,04070782 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,01731684 0,04065596 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,01731684 0,04060424 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,01731684 0,04055265 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,01731684 0,04050118 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,01731684 0,04044985 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,01731684 0,04039865 ! protein polyubiquitination GO:0000209 10 10 0,000 0,01731684 0,04034757 ! glutamate metabolic process GO:0006536 11 10 0,000 0,01731684 0,04029663 ! plasma membrane organization GO:0007009 10 10 0,000 0,01731684 0,04024582 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,01731684 0,04019513 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-substrate junction assembly GO:0007044 11 10 0,000 0,01731684 0,04014457 ! lysosomal transport GO:0007041 10 10 0,000 0,01731684 0,04009414 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,01731684 0,04004383 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,01731684 0,03999365 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,01731684 0,03994359 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,01731684 0,03989366 ! exocrine system development GO:0035272 10 10 0,000 0,01731684 0,03984386 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,01731684 0,03979418 ! neuromuscular junction development GO:0007528 10 10 0,000 0,01731684 0,03974462 ! embryo implantation GO:0007566 11 10 0,000 0,01731684 0,03969519 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,01731684 0,03964588 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,01731684 0,03959669 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,01731684 0,03954762 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,01731684 0,03949868 ! protein export from nucleus GO:0006611 10 10 0,000 0,01731684 0,03944985 ! negative regulation of immune response GO:0050777 10 10 0,000 0,01731684 0,03940115 ! cytolysis GO:0019835 10 10 0,000 0,01731684 0,03935257 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,01731684 0,0393041 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,01731684 0,03925576 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,01731684 0,03920753 ! histone deacetylation GO:0016575 10 10 0,000 0,01731684 0,03915943 ! mRNA splice site selection GO:0006376 11 10 0,000 0,01731684 0,03911144 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,01731684 0,03906356 ! gland morphogenesis GO:0022612 10 10 0,000 0,01731684 0,03901581 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,01731684 0,03896817 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,01731684 0,03892065 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,01731684 0,03887324 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,01731684 0,03882595 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,01731684 0,03877877 ! regulation of epidermis development GO:0045682 10 10 0,000 0,01731684 0,03873171 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,01731684 0,03868477 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,01731684 0,03863793 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,01731684 0,03859121 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,01731684 0,0385446 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,01731684 0,03849811 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,01731684 0,03845172 ! nerve development GO:0021675 10 10 0,000 0,01731684 0,03840545 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 0,01731684 0,03835929 ! gut development GO:0048565 10 10 0,000 0,01731684 0,03831324 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,01731684 0,0382673 ! negative regulation of homeostatic process GO:0032845 10 10 0,000 0,01731684 0,03822148 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,01731684 0,03817576 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,01731684 0,03813015 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,01731684 0,03808464 ! protein stabilization GO:0050821 10 10 0,000 0,01731684 0,03803925 ! protein secretion GO:0009306 11 11 0,000 0,01903331 0,04176 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,01903331 0,04171034 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,01903331 0,04166081 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,01903331 0,04161139 ! negative regulation of defense response GO:0031348 11 11 0,000 0,01903331 0,04156208 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,01903331 0,0415129 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,01903331 0,04146383 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,01903331 0,04141487 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,01903331 0,04136604 ! signal complex assembly GO:0007172 11 11 0,000 0,01903331 0,04131731 ! microtubule-based transport GO:0010970 11 11 0,000 0,01903331 0,0412687 ! endothelial cell migration GO:0043542 11 11 0,000 0,01903331 0,04122021 ! peroxisomal transport GO:0043574 11 11 0,000 0,01903331 0,04117183 ! protein amino acid methylation GO:0006479 11 11 0,000 0,01903331 0,04112356 GO:0008213|protein amino acid alkylation, ! protein amino acid acetylation GO:0006473 11 11 0,000 0,01903331 0,04107541 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 0,000 0,01903331 0,04102737 GO:0032388|positive regulation of intracellular transport, ! heart contraction GO:0060047 11 11 0,000 0,01903331 0,04097944 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,01903331 0,04093162 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,01903331 0,04088391 ! T cell proliferation GO:0042098 11 11 0,000 0,01903331 0,04083632 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,01903331 0,04078884 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,01903331 0,04074146 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,01903331 0,0406942 ! spinal cord development GO:0021510 11 11 0,000 0,01903331 0,04064704 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,01903331 0,0406 ! smooth muscle contraction GO:0006939 11 11 0,000 0,01903331 0,04055306 ! cellular response to starvation GO:0009267 11 11 0,000 0,01903331 0,04050623 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 0,000 0,01903331 0,04045951 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,01903331 0,0404129 ! digestive system process GO:0022600 11 11 0,000 0,01903331 0,0403664 ! mitotic spindle organization GO:0007052 11 11 0,000 0,01903331 0,04032 ! fucose metabolic process GO:0006004 11 11 0,000 0,01903331 0,04027371 ! membrane budding GO:0006900 11 11 0,000 0,01903331 0,04022752 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,01903331 0,04018144 ! monoamine transport GO:0015844 11 11 0,000 0,01903331 0,04013547 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,01903331 0,0400896 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,01903331 0,04004383 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 0,000 0,01903331 0,03999817 ! body fluid secretion GO:0007589 11 11 0,000 0,01903331 0,03995262 ! G1/S transition checkpoint GO:0031575 12 11 0,000 0,01903331 0,03990717 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,01903331 0,03986182 ! intermediate filament-based process GO:0045103 11 11 0,000 0,01903331 0,03981657 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,01903331 0,03977143 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 11 11 0,000 0,01903331 0,03972639 ! membrane depolarization GO:0051899 11 11 0,000 0,01903331 0,03968145 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,01903331 0,03963661 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,01903331 0,03959187 ! regulation of monooxygenase activity GO:0032768 11 11 0,000 0,01903331 0,03954724 ! oogenesis GO:0048477 11 11 0,000 0,01903331 0,0395027 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,01903331 0,03945827 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,01903331 0,03941393 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 0,000 0,01903331 0,0393697 GO:0006109|regulation of carbohydrate metabolic process, ! vitamin transport GO:0051180 11 11 0,000 0,01903331 0,03932556 ! muscle maintenance GO:0046716 12 11 0,000 0,01903331 0,03928152 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,01903331 0,03923758 ! hindbrain development GO:0030902 11 11 0,000 0,01903331 0,03919374 ! steroid catabolic process GO:0006706 11 11 0,000 0,01903331 0,03915 ! endocrine process GO:0050886 11 11 0,000 0,01903331 0,03910635 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,01903331 0,03906281 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,01903331 0,03901935 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,01903331 0,038976 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,01903331 0,03893274 ! negative regulation of lymphocyte activation GO:0051250 11 11 0,000 0,01903331 0,03888958 ! positive regulation of protein catabolic process GO:0045732 12 12 0,000 0,02074704 0,04234419 ! translational initiation GO:0006413 12 12 0,000 0,02074704 0,04229735 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,02074704 0,04225061 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,02074704 0,04220397 ! initiation of viral infection GO:0019059 12 12 0,000 0,02074704 0,04215744 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,02074704 0,04211101 ! iron ion transport GO:0006826 13 12 0,000 0,02074704 0,04206469 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,02074704 0,04201846 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,02074704 0,04197234 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,02074704 0,04192632 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,02074704 0,04188039 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,02074704 0,04183457 ! collagen metabolic process GO:0032963 12 12 0,000 0,02074704 0,04178885 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,02074704 0,04174323 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,02074704 0,04169771 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,02074704 0,04165229 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,02074704 0,04160696 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,02074704 0,04156174 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,02074704 0,04151661 GO:0042744|hydrogen peroxide catabolic process, ! microtubule organizing center organization GO:0031023 12 12 0,000 0,02074704 0,04147158 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,02074704 0,04142665 ! retinoid metabolic process GO:0001523 12 12 0,000 0,02074704 0,04138182 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,02074704 0,04133708 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,02074704 0,04129244 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,02074704 0,0412479 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,02074704 0,04120345 ! acute-phase response GO:0006953 12 12 0,000 0,02074704 0,0411591 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,02074704 0,04111484 ! vacuolar transport GO:0007034 12 12 0,000 0,02074704 0,04107068 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,02074704 0,04102661 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,02074704 0,04098264 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,02074704 0,04093876 ! osteoblast differentiation GO:0001649 12 12 0,000 0,02074704 0,04089497 ! male gonad development GO:0008584 12 12 0,000 0,02074704 0,04085128 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,02074704 0,04080768 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,02074704 0,04076418 ! renal system process GO:0003014 12 12 0,000 0,02074704 0,04072077 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,02074704 0,04067745 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,02074704 0,04063422 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,02074704 0,04059108 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,02074704 0,04054804 ! pallium development GO:0021543 13 12 0,000 0,02074704 0,04050509 ! cell fate determination GO:0001709 12 12 0,000 0,02074704 0,04046222 ! regulation of chromosome organization GO:0033044 12 12 0,000 0,02074704 0,04041945 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,02074704 0,04037677 ! somitogenesis GO:0001756 13 12 0,000 0,02074704 0,04033418 ! G1 phase GO:0051318 13 12 0,000 0,02074704 0,04029168 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,02074704 0,04024926 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,02074704 0,04020694 ! detection of light stimulus GO:0009583 13 12 0,000 0,02074704 0,04016471 ! synaptogenesis GO:0007416 12 12 0,000 0,02074704 0,04012256 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,02074704 0,0400805 ! hormone transport GO:0009914 12 12 0,000 0,02074704 0,04003853 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,02074704 0,03999665 ! heme biosynthetic process GO:0006783 12 12 0,000 0,02074704 0,03995486 ! spermatid differentiation GO:0048515 13 12 0,000 0,02074704 0,03991315 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,02074704 0,03987153 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,02074704 0,03983 ! neural tube closure GO:0001843 13 12 0,000 0,02074704 0,03978855 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 0,000 0,02074704 0,03974719 ! negative regulation of translation GO:0017148 12 12 0,000 0,02074704 0,03970592 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,02074704 0,03966473 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 0,000 0,02074704 0,03962363 ! positive regulation of DNA replication GO:0045740 14 13 0,000 0,02245803 0,04284694 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 0,000 0,02245803 0,04280263 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,02245803 0,04275841 GO:0016444|somatic cell DNA recombination, ! phenol metabolic process GO:0018958 13 13 0,000 0,02245803 0,04271429 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,02245803 0,04267025 ! gluconeogenesis GO:0006094 13 13 0,000 0,02245803 0,04262631 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,02245803 0,04258245 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,02245803 0,04253869 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,02245803 0,04249501 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,02245803 0,04245143 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,02245803 0,04240793 ! regeneration GO:0031099 13 13 0,000 0,02245803 0,04236453 ! keratinization GO:0031424 13 13 0,000 0,02245803 0,04232121 ! post-embryonic development GO:0009791 14 13 0,000 0,02245803 0,04227798 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,02245803 0,04223484 ! patterning of blood vessels GO:0001569 13 13 0,000 0,02245803 0,04219179 ! vasculogenesis GO:0001570 13 13 0,000 0,02245803 0,04214882 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,02245803 0,04210594 ! regulation of innate immune response GO:0045088 13 13 0,000 0,02245803 0,04206315 ! mitochondrial membrane organization GO:0007006 13 13 0,000 0,02245803 0,04202045 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 0,000 0,02245803 0,04197783 ! negative regulation of DNA replication GO:0008156 13 13 0,000 0,02245803 0,0419353 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,02245803 0,04189286 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,02245803 0,0418505 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,02245803 0,04180823 ! autophagy GO:0006914 13 13 0,000 0,02245803 0,04176604 ! receptor metabolic process GO:0043112 14 13 0,000 0,02245803 0,04172393 ! actin filament bundle formation GO:0051017 13 13 0,000 0,02245803 0,04168192 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,02245803 0,04163998 ! ureteric bud development GO:0001657 13 13 0,000 0,02245803 0,04159813 ! cell aging GO:0007569 13 13 0,000 0,02245803 0,04155637 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 0,000 0,02245803 0,04151469 ! regulation of endothelial cell migration GO:0010594 13 13 0,000 0,02245803 0,04147309 ! response to endoplasmic reticulum stress GO:0034976 13 13 0,000 0,02245803 0,04143157 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,02245803 0,04139014 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,02245803 0,04134879 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,02245803 0,04130753 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,02245803 0,04126634 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,02245803 0,04122524 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,02245803 0,04118422 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,02245803 0,04114328 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,02245803 0,04110243 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,02245803 0,04106165 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,02245803 0,04102095 ! vasodilation GO:0042311 14 13 0,000 0,02245803 0,04098034 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,02245803 0,04093981 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,02245803 0,04089935 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,02245803 0,04085898 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 0,02245803 0,04081868 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 0,000 0,02245803 0,04077847 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,02245803 0,04073833 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,02245803 0,04069827 ! immunoglobulin production GO:0002377 13 13 0,000 0,02245803 0,04065829 GO:0002440|production of molecular mediator of immune response, ! negative regulation of intracellular transport GO:0032387 13 13 0,000 0,02245803 0,04061839 ! negative regulation of leukocyte activation GO:0002695 13 13 0,000 0,02245803 0,04057857 ! cell-cell junction organization GO:0045216 13 13 0,000 0,02245803 0,04053883 ! regulation of cell-substrate adhesion GO:0010810 14 13 0,000 0,02245803 0,04049916 GO:0001952|regulation of cell-matrix adhesion, ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,02245803 0,04045957 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,02245803 0,04042006 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,02245803 0,04038063 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,02245803 0,04034127 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,02245803 0,04030199 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,02245803 0,04026279 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,02245803 0,04022366 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,02245803 0,04018461 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,02245803 0,04014563 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,02245803 0,04010673 ! blastocyst development GO:0001824 13 13 0,000 0,02245803 0,0400679 ! telomere organization GO:0032200 13 13 0,000 0,02245803 0,04002915 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,02245803 0,03999048 ! regulation of amine transport GO:0051952 13 13 0,000 0,02245803 0,03995188 ! tissue homeostasis GO:0001894 13 13 0,000 0,02245803 0,03991335 GO:0048871|multicellular organismal homeostasis, ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,02245803 0,0398749 ! protein tetramerization GO:0051262 13 13 0,000 0,02245803 0,03983652 ! neuron fate commitment GO:0048663 14 14 0,000 0,02416627 0,04282542 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,02416627 0,04278428 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,02416627 0,04274322 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,02416627 0,04270224 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,02416627 0,04266134 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,02416627 0,04262051 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,02416627 0,04257977 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,02416627 0,0425391 ! protein amino acid acylation GO:0043543 14 14 0,000 0,02416627 0,04249851 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,02416627 0,04245799 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,02416627 0,04241756 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,02416627 0,0423772 ! vesicle docking GO:0048278 14 14 0,000 0,02416627 0,04233692 ! superoxide metabolic process GO:0006801 15 14 0,000 0,02416627 0,04229671 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,02416627 0,04225658 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,02416627 0,04221653 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,02416627 0,04217655 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,02416627 0,04213665 ! hair cycle GO:0042633 14 14 0,000 0,02416627 0,04209682 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,02416627 0,04205707 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 0,000 0,02416627 0,04201739 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,02416627 0,04197779 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,02416627 0,04193826 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,02416627 0,04189881 ! lysosome organization GO:0007040 14 14 0,000 0,02416627 0,04185943 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,02416627 0,04182013 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,02416627 0,0417809 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,02416627 0,04174174 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,02416627 0,04170265 ! primary neural tube formation GO:0014020 15 14 0,000 0,02416627 0,04166364 ! peptide cross-linking GO:0018149 14 14 0,000 0,02416627 0,04162471 ! regulation of behavior GO:0050795 14 14 0,000 0,02416627 0,04158584 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,02416627 0,04154705 ! base-excision repair GO:0006284 14 14 0,000 0,02416627 0,04150833 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,02416627 0,04146968 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,02416627 0,0414311 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,02416627 0,0413926 ! formation of primary germ layer GO:0001704 14 14 0,000 0,02416627 0,04135416 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,02416627 0,0413158 ! collagen fibril organization GO:0030199 14 14 0,000 0,02416627 0,04127751 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,02416627 0,04123929 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,02416627 0,04120114 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,02416627 0,04116306 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,02416627 0,04112506 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,02416627 0,04108712 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,02416627 0,04104925 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,02416627 0,04101145 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,02416627 0,04097372 ! protein import into nucleus, translocation GO:0000060 15 15 0,000 0,02587178 0,04382508 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,02587178 0,04378483 ! positive regulation of ossification GO:0045778 15 15 0,000 0,02587178 0,04374466 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,02587178 0,04370457 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,02587178 0,04366454 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,02587178 0,0436246 ! response to vitamin GO:0033273 15 15 0,000 0,02587178 0,04358472 ! regulation of transcription factor import into nucleus GO:0042990 15 15 0,000 0,02587178 0,04354492 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,02587178 0,04350518 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,02587178 0,04346553 ! ovarian follicle development GO:0001541 15 15 0,000 0,02587178 0,04342594 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,02587178 0,04338643 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,02587178 0,04334698 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,02587178 0,04330761 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,02587178 0,04326831 ! ER-nuclear signaling pathway GO:0006984 15 15 0,000 0,02587178 0,04322909 ! heme metabolic process GO:0042168 15 15 0,000 0,02587178 0,04318993 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,02587178 0,04315084 ! chromosome condensation GO:0030261 15 15 0,000 0,02587178 0,04311183 ! response to starvation GO:0042594 15 15 0,000 0,02587178 0,04307288 ! response to ionizing radiation GO:0010212 16 15 0,000 0,02587178 0,04303401 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,02587178 0,04299521 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,02587178 0,04295647 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,02587178 0,04291781 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,02587178 0,04287921 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,02587178 0,04284069 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,02587178 0,04280223 ! phospholipid transport GO:0015914 15 15 0,000 0,02587178 0,04276384 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,02587178 0,04272552 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,02587178 0,04268727 ! glutathione metabolic process GO:0006749 16 15 0,000 0,02587178 0,04264909 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,02587178 0,04261098 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,02587178 0,04257293 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,02587178 0,04253495 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,02587178 0,04249704 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,02587178 0,0424592 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,02587178 0,04242143 ! negative regulation of cell activation GO:0050866 15 15 0,000 0,02587178 0,04238372 ! protein homooligomerization GO:0051260 15 15 0,000 0,02587178 0,04234608 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,02587178 0,0423085 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,02757455 0,0450531 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,02757455 0,04501319 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,02757455 0,04497336 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,02757455 0,04493359 ! learning GO:0007612 16 16 0,000 0,02757455 0,0448939 ! circadian rhythm GO:0007623 16 16 0,000 0,02757455 0,04485428 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,02757455 0,04481472 ! positive regulation of mitosis GO:0045840 16 16 0,000 0,02757455 0,04477524 GO:0051785|positive regulation of nuclear division, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 0,000 0,02757455 0,04473582 ! vacuole organization GO:0007033 16 16 0,000 0,02757455 0,04469648 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,02757455 0,0446572 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,02757455 0,04461799 ! vesicle targeting GO:0006903 17 16 0,000 0,02757455 0,04457885 ! segmentation GO:0035282 17 16 0,000 0,02757455 0,04453978 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,02757455 0,04450078 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,02757455 0,04446185 ! iron ion homeostasis GO:0055072 16 16 0,000 0,02757455 0,04442298 ! positive regulation of cell development GO:0010720 16 16 0,000 0,02757455 0,04438419 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,02757455 0,04434546 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,02757455 0,04430679 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,02757455 0,0442682 ! cell fate specification GO:0001708 16 16 0,000 0,02757455 0,04422967 ! pentose metabolic process GO:0019321 16 16 0,000 0,02757455 0,04419121 ! fatty acid transport GO:0015908 16 16 0,000 0,02757455 0,04415282 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,02757455 0,04411449 ! cellular response to nutrient levels GO:0031669 16 16 0,000 0,02757455 0,04407623 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,02757455 0,04403804 ! cofactor catabolic process GO:0051187 16 16 0,000 0,02757455 0,04399991 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,02757455 0,04396185 ! polyol metabolic process GO:0019751 16 16 0,000 0,02757455 0,04392385 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,02757455 0,04388592 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,02757455 0,04384805 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,02757455 0,04381025 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,02757455 0,04377252 GO:0001841|neural tube formation, ! positive regulation of catabolic process GO:0009896 16 16 0,000 0,02757455 0,04373485 ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,02757455 0,04369724 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,02757455 0,0436597 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,02757455 0,04362223 ! regulation of coagulation GO:0050818 17 16 0,000 0,02757455 0,04358481 ! regulation of fibroblast proliferation GO:0048145 17 17 0,000 0,02927459 0,04623228 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,02927459 0,0461927 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 0,000 0,02927459 0,04615319 ! positive regulation of cell adhesion GO:0045785 17 17 0,000 0,02927459 0,04611374 ! myelination GO:0042552 17 17 0,000 0,02927459 0,04607436 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,02927459 0,04603505 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,02927459 0,0459958 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,02927459 0,04595662 ! leukocyte adhesion GO:0007159 17 17 0,000 0,02927459 0,04591751 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,02927459 0,04587847 ! sensory perception of smell GO:0007608 17 17 0,000 0,02927459 0,04583949 ! glucose transport GO:0015758 17 17 0,000 0,02927459 0,04580057 ! cell junction assembly GO:0034329 18 17 0,000 0,02927459 0,04576173 ! tissue remodeling GO:0048771 17 17 0,000 0,02927459 0,04572295 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,02927459 0,04568423 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,02927459 0,04564558 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,02927459 0,045607 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,02927459 0,04556848 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,02927459 0,04553002 ! neural crest cell development GO:0014032 19 17 0,000 0,02927459 0,04549163 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 0,02927459 0,04545331 ! negative regulation of cell development GO:0010721 18 17 0,000 0,02927459 0,04541505 GO:0050768|negative regulation of neurogenesis, ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,02927459 0,04537685 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,02927459 0,04533872 ! regulation of oxidoreductase activity GO:0051341 17 17 0,000 0,02927459 0,04530065 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,02927459 0,04526265 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,02927459 0,04522471 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,02927459 0,04518683 ! pigmentation GO:0043473 17 17 0,000 0,02927459 0,04514902 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,02927459 0,04511127 ! adult locomotory behavior GO:0008344 17 17 0,000 0,02927459 0,04507358 ! embryonic organ development GO:0048568 17 17 0,000 0,02927459 0,04503596 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,02927459 0,0449984 ! liver development GO:0001889 17 17 0,000 0,02927459 0,0449609 ! gene silencing GO:0016458 17 17 0,000 0,02927459 0,04492346 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,03097191 0,04748855 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,03097191 0,04744907 ! regulation of cellular catabolic process GO:0031329 18 18 0,000 0,03097191 0,04740966 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,03097191 0,04737032 ! meiosis I GO:0007127 18 18 0,000 0,03097191 0,04733104 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,03097191 0,04729183 ! membrane docking GO:0022406 18 18 0,000 0,03097191 0,04725268 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,03097191 0,04721359 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,03097191 0,04717458 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,03097191 0,04713562 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,03097191 0,04709673 ! hexose transport GO:0008645 18 18 0,000 0,03097191 0,0470579 GO:0015749|monosaccharide transport, ! cholesterol homeostasis GO:0042632 18 18 0,000 0,03097191 0,04701914 GO:0055092|sterol homeostasis, ! striated muscle contraction GO:0006941 18 18 0,000 0,03097191 0,04698044 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,03097191 0,04694181 GO:0006639|acylglycerol metabolic process, ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,03097191 0,04690323 ! ceramide metabolic process GO:0006672 18 18 0,000 0,03097191 0,04686473 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,03097191 0,04682628 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,03097191 0,0467879 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,03097191 0,04674958 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,03097191 0,04671132 ! B cell differentiation GO:0030183 18 18 0,000 0,03097191 0,04667313 ! cellular response to extracellular stimulus GO:0031668 18 18 0,000 0,03097191 0,046635 ! ensheathment of neurons GO:0007272 18 18 0,000 0,03097191 0,04659693 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 18 18 0,000 0,03097191 0,04655892 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,03097191 0,04652097 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,03097191 0,04648309 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 0,000 0,03097191 0,04644527 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,03097191 0,04640751 ! DNA damage checkpoint GO:0000077 19 19 0,000 0,03266651 0,04890689 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,03266651 0,04886719 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,03266651 0,04882756 GO:0006956|complement activation, ! negative regulation of DNA metabolic process GO:0051053 19 19 0,000 0,03266651 0,04878799 ! glial cell differentiation GO:0010001 19 19 0,000 0,03266651 0,04874849 ! regulation of pH GO:0006885 19 19 0,000 0,03266651 0,04870905 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,03266651 0,04866967 ! feeding behavior GO:0007631 19 19 0,000 0,03266651 0,04863036 ! regulation of endothelial cell proliferation GO:0001936 19 19 0,000 0,03266651 0,04859111 ! peroxisome organization GO:0007031 19 19 0,000 0,03266651 0,04855192 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,03266651 0,0485128 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,03266651 0,04847374 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,03266651 0,04843474 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 0,000 0,03266651 0,04839581 ! metanephros development GO:0001656 19 19 0,000 0,03266651 0,04835693 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,03266651 0,04831812 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,03266651 0,04827938 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,03266651 0,04824069 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,03266651 0,04820207 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,03266651 0,04816351 ! peripheral nervous system development GO:0007422 19 19 0,000 0,03266651 0,04812501 ! regulation of protein stability GO:0031647 19 19 0,000 0,03266651 0,04808657 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,03266651 0,04804819 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,03266651 0,04800987 ! dorsal/ventral pattern formation GO:0009953 19 19 0,000 0,03266651 0,04797162 ! eye morphogenesis GO:0048592 19 19 0,000 0,03266651 0,04793342 ! regulation of cell shape GO:0008360 21 19 0,000 0,03266651 0,04789529 ! placenta development GO:0001890 19 19 0,000 0,03266651 0,04785722 ! response to heat GO:0009408 19 19 0,000 0,03266651 0,04781921 ! vesicle localization GO:0051648 20 19 0,000 0,03266651 0,04778126 ! regulation of muscle development GO:0048634 21 20 0,000 0,03435839 0,05021611 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,03435839 0,05017632 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,03435839 0,0501366 ! negative regulation of binding GO:0051100 21 20 0,000 0,03435839 0,05009693 ! organic ether metabolic process GO:0018904 20 20 0,000 0,03435839 0,05005733 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,03435839 0,05001779 ! neural tube development GO:0021915 21 20 0,000 0,03435839 0,04997831 ! nucleus organization GO:0006997 20 20 0,000 0,03435839 0,0499389 ! phagocytosis GO:0006909 21 20 0,000 0,03435839 0,04989954 ! positive regulation of gene-specific transcription GO:0043193 20 20 0,000 0,03435839 0,04986025 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,03435839 0,04982102 ! protein targeting to membrane GO:0006612 22 20 0,000 0,03435839 0,04978186 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,03435839 0,04974275 ! chromatin remodeling GO:0006338 20 20 0,000 0,03435839 0,0497037 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,03435839 0,04966472 ! peptidyl-tyrosine modification GO:0018212 21 20 0,000 0,03435839 0,0496258 ! lipid oxidation GO:0034440 20 20 0,000 0,03435839 0,04958694 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,03435839 0,04954814 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,03435839 0,0495094 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,03435839 0,04947072 ! RNA modification GO:0009451 20 20 0,000 0,03435839 0,0494321 ! single fertilization GO:0007338 21 20 0,000 0,03435839 0,04939354 ! regulation of B cell activation GO:0050864 20 20 0,000 0,03435839 0,04935504 ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,03604756 0,05174117 ! mRNA catabolic process GO:0006402 21 21 0,000 0,03604756 0,0517009 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 0,000 0,03604756 0,0516607 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,03604756 0,05162056 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! mammary gland development GO:0030879 23 21 0,000 0,03604756 0,05158048 ! protein amino acid lipidation GO:0006497 21 21 0,000 0,03604756 0,05154046 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,03604756 0,05150051 ! Notch signaling pathway GO:0007219 22 21 0,000 0,03604756 0,05146062 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,03604756 0,05142079 ! ear morphogenesis GO:0042471 21 21 0,000 0,03604756 0,05138102 ! organic anion transport GO:0015711 21 21 0,000 0,03604756 0,05134131 ! cholesterol transport GO:0030301 21 21 0,000 0,03604756 0,05130167 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,03604756 0,05126208 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,03604756 0,05122256 GO:0032313|regulation of Rab GTPase activity, ! DNA integrity checkpoint GO:0031570 21 21 0,000 0,03604756 0,0511831 ! regulation of protein import into nucleus GO:0042306 21 21 0,000 0,03604756 0,05114369 ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,03604756 0,05110435 ! regulation of action potential in neuron GO:0019228 21 21 0,000 0,03604756 0,05106507 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,03604756 0,05102585 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,03604756 0,05098669 ! regulation of proteolysis GO:0030162 21 21 0,000 0,03604756 0,05094759 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,03604756 0,05090855 ! negative regulation of protein transport GO:0051224 21 21 0,000 0,03604756 0,05086957 ! positive regulation of transcription factor activity GO:0051091 22 22 0,000 0,03773402 0,05320873 GO:0090047|positive regulation of transcription regulator activity, ! RNA export from nucleus GO:0006405 22 22 0,000 0,03773402 0,05316805 ! positive regulation of DNA metabolic process GO:0051054 23 22 0,000 0,03773402 0,05312743 ! sister chromatid segregation GO:0000819 22 22 0,000 0,03773402 0,05308687 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,03773402 0,05304638 ! regulation of ion transport GO:0043269 22 22 0,000 0,03773402 0,05300595 ! odontogenesis GO:0042476 22 22 0,000 0,03773402 0,05296558 ! cell junction organization GO:0034330 23 22 0,000 0,03773402 0,05292527 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,03773402 0,05288502 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,03773402 0,05284484 ! embryonic skeletal system development GO:0048706 22 22 0,000 0,03773402 0,05280471 ! maintenance of protein location in cell GO:0032507 23 22 0,000 0,03773402 0,05276465 ! ovulation cycle process GO:0022602 22 22 0,000 0,03773402 0,05272464 ! spindle organization GO:0007051 22 22 0,000 0,03773402 0,0526847 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,03773402 0,05264482 ! cell chemotaxis GO:0060326 23 22 0,000 0,03773402 0,052605 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,03773402 0,05256523 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,03773402 0,05252553 ! male sex differentiation GO:0046661 22 22 0,000 0,03773402 0,05248589 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,03773402 0,05244631 ! biopolymer methylation GO:0043414 22 22 0,000 0,03773402 0,05240679 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,03773402 0,05236732 ! detection of external stimulus GO:0009581 23 22 0,000 0,03773402 0,05232792 ! neuron migration GO:0001764 22 22 0,000 0,03773402 0,05228857 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,03773402 0,05224929 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,03773402 0,05221006 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,03773402 0,0521709 ! aerobic respiration GO:0009060 22 22 0,000 0,03773402 0,05213179 ! cytokine production GO:0001816 22 22 0,000 0,03773402 0,05209274 ! cytokinesis GO:0000910 23 22 0,000 0,03773402 0,05205375 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,03773402 0,05201481 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,03941778 0,05429519 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,03941778 0,05425464 ! viral infectious cycle GO:0019058 23 23 0,000 0,03941778 0,05421415 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,03941778 0,05417372 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,03941778 0,05413336 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,03941778 0,05409305 ! mitotic cell cycle checkpoint GO:0007093 24 23 0,000 0,03941778 0,0540528 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,03941778 0,05401261 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,03941778 0,05397248 ! endocrine system development GO:0035270 23 23 0,000 0,03941778 0,05393242 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,03941778 0,05389241 ! female gonad development GO:0008585 23 23 0,000 0,03941778 0,05385246 ! monovalent inorganic cation homeostasis GO:0055067 23 23 0,000 0,03941778 0,05381257 ! lipid homeostasis GO:0055088 23 23 0,000 0,03941778 0,05377273 ! calcium-mediated signaling GO:0019722 23 23 0,000 0,03941778 0,05373296 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,03941778 0,05369325 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,03941778 0,05365359 ! cell projection assembly GO:0030031 25 23 0,000 0,03941778 0,053614 ! mitochondrial transport GO:0006839 24 24 0,000 0,04109883 0,05585925 ! regulation of action potential GO:0001508 24 24 0,000 0,04109883 0,05581809 ! gliogenesis GO:0042063 24 24 0,000 0,04109883 0,05577699 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,04109883 0,05573594 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,04109883 0,05569496 ! glucose homeostasis GO:0042593 24 24 0,000 0,04109883 0,05565404 GO:0033500|carbohydrate homeostasis, ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,04109883 0,05561318 ! T cell differentiation GO:0030217 24 24 0,000 0,04109883 0,05557237 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,04109883 0,05553163 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,04109883 0,05549095 ! ovulation cycle GO:0042698 24 24 0,000 0,04109883 0,05545033 ! fertilization GO:0009566 25 24 0,000 0,04109883 0,05540976 ! maintenance of protein location GO:0045185 25 24 0,000 0,04109883 0,05536926 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,04109883 0,05532881 ! androgen receptor signaling pathway GO:0030521 24 24 0,000 0,04109883 0,05528843 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,04109883 0,0552481 ! glucan metabolic process GO:0044042 25 24 0,000 0,04109883 0,05520783 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! negative regulation of secretion GO:0051048 26 25 0,000 0,04277719 0,05742051 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,04277719 0,05737872 ! regulation of gene-specific transcription GO:0032583 25 25 0,000 0,04277719 0,05733699 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,04277719 0,05729532 ! cellular component disassembly GO:0022411 26 25 0,000 0,04277719 0,05725371 ! endosome transport GO:0016197 25 25 0,000 0,04277719 0,05721216 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,04277719 0,05717067 ! regulation of intracellular protein transport GO:0033157 25 25 0,000 0,04277719 0,05712925 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,04277719 0,05708788 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,04277719 0,05704657 ! regulation of T cell proliferation GO:0042129 25 25 0,000 0,04277719 0,05700532 ! excretion GO:0007588 25 25 0,000 0,04277719 0,05696413 ! positive regulation of DNA binding GO:0043388 26 25 0,000 0,04277719 0,056923 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,04277719 0,05688193 ! gastrulation GO:0007369 25 25 0,000 0,04277719 0,05684092 ! heart morphogenesis GO:0003007 25 25 0,000 0,04277719 0,05679997 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,04277719 0,05675908 ! regulation of endocytosis GO:0030100 25 25 0,000 0,04277719 0,05671824 ! negative regulation of immune system process GO:0002683 25 25 0,000 0,04277719 0,05667747 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,04277719 0,05663675 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,04277719 0,05659609 ! positive regulation of binding GO:0051099 27 26 0,000 0,04445285 0,05877088 ! positive regulation of defense response GO:0031349 26 26 0,000 0,04445285 0,05872875 ! glycolysis GO:0006096 26 26 0,000 0,04445285 0,05868668 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,04445285 0,05864467 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,04445285 0,05860272 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,04445285 0,05856083 ! negative regulation of cell migration GO:0030336 26 26 0,000 0,04445285 0,058519 ! cellular defense response GO:0006968 26 26 0,000 0,04445285 0,05847724 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,04445285 0,05843553 ! regulation of T cell differentiation GO:0045580 26 26 0,000 0,04445285 0,05839387 ! double-strand break repair GO:0006302 27 26 0,000 0,04445285 0,05835228 ! regulation of protein secretion GO:0050708 26 26 0,000 0,04445285 0,05831075 ! germ cell development GO:0007281 27 26 0,000 0,04445285 0,05826928 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,04445285 0,05822787 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,04445285 0,05818651 ! maintenance of location in cell GO:0051651 27 26 0,000 0,04445285 0,05814521 ! synapse organization GO:0050808 26 26 0,000 0,04445285 0,05810398 ! chloride transport GO:0006821 27 27 0,000 0,04612583 0,06024798 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 0,000 0,04612583 0,06020531 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,04612583 0,0601627 ! energy reserve metabolic process GO:0006112 28 27 0,000 0,04612583 0,06012015 ! learning or memory GO:0007611 28 27 0,000 0,04612583 0,06007767 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,04612583 0,06003524 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,04612583 0,05999287 ! peptide metabolic process GO:0006518 29 27 0,000 0,04612583 0,05995056 ! mesenchymal cell development GO:0014031 29 27 0,000 0,04612583 0,05990831 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! inner ear development GO:0048839 27 27 0,000 0,04612583 0,05986613 ! defense response to bacterium GO:0042742 27 27 0,000 0,04612583 0,059824 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,04612583 0,05978193 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,04612583 0,05973991 ! cell growth GO:0016049 27 27 0,000 0,04612583 0,05969796 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,04779612 0,06181631 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,04779612 0,06177296 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,04779612 0,06172967 ! carbohydrate transport GO:0008643 28 28 0,000 0,04779612 0,06168644 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,04779612 0,06164328 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,04779612 0,06160017 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,04779612 0,06155712 ! histone modification GO:0016570 28 28 0,000 0,04779612 0,06151413 ! protein amino acid autophosphorylation GO:0046777 28 28 0,000 0,04779612 0,06147121 ! developmental growth GO:0048589 28 28 0,000 0,04779612 0,06142834 ! regulation of mast cell proliferation GO:0070666 28 28 0,000 0,04779612 0,06138553 ! cartilage development GO:0051216 29 28 0,000 0,04779612 0,06134279 ! positive regulation of cell cycle GO:0045787 29 29 0,000 0,04946372 0,06343886 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,04946372 0,06339474 ! viral reproductive process GO:0022415 29 29 0,000 0,04946372 0,06335069 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,04946372 0,0633067 ! leukocyte migration GO:0050900 30 29 0,000 0,04946372 0,06326276 ! branching morphogenesis of a tube GO:0048754 29 29 0,000 0,04946372 0,06321889 ! regulation of epithelial cell proliferation GO:0050678 29 29 0,000 0,04946372 0,06317508 ! regulation of lymphocyte proliferation GO:0050670 29 29 0,000 0,04946372 0,06313133 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! antigen processing and presentation GO:0019882 29 29 0,000 0,04946372 0,06308764 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,04946372 0,06304401 ! tRNA processing GO:0008033 29 29 0,000 0,04946372 0,06300044 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,04946372 0,06295693 ! covalent chromatin modification GO:0016569 29 29 0,000 0,04946372 0,06291349 ! adult behavior GO:0030534 30 29 0,000 0,04946372 0,0628701 ! positive regulation of protein transport GO:0051222 29 29 0,000 0,04946372 0,06282677 ! response to UV GO:0009411 29 29 0,000 0,04946372 0,0627835 ! transition metal ion transport GO:0000041 31 30 0,000 0,05112865 0,0648521 ! RNA catabolic process GO:0006401 30 30 0,000 0,05112865 0,0648075 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,05112865 0,06476296 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,05112865 0,06471848 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,05112865 0,06467406 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,05112865 0,0646297 ! activation of phospholipase C activity GO:0007202 30 30 0,000 0,05112865 0,06458541 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of response to external stimulus GO:0032103 30 30 0,000 0,05112865 0,06454117 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,05112865 0,06449699 ! skeletal system morphogenesis GO:0048705 31 30 0,000 0,05112865 0,06445288 ! response to temperature stimulus GO:0009266 30 30 0,000 0,05112865 0,06440882 ! regulation of ossification GO:0030278 30 30 0,000 0,05112865 0,06436483 ! vascular process in circulatory system GO:0003018 31 30 0,000 0,05112865 0,06432089 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,05112865 0,06427702 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,05112865 0,0642332 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,05112865 0,06418945 ! vesicle organization GO:0016050 30 30 0,000 0,05112865 0,06414575 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,05112865 0,06410211 ! establishment of organelle localization GO:0051656 31 30 0,000 0,05112865 0,06405854 ! regulation of translational initiation GO:0006446 31 31 0,000 0,05279091 0,06609623 ! membrane fusion GO:0006944 31 31 0,000 0,05279091 0,06605135 ! B cell activation GO:0042113 31 31 0,000 0,05279091 0,06600654 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,05279091 0,06596179 ! positive regulation of phospholipase activity GO:0010518 31 31 0,000 0,05279091 0,0659171 ! ion transmembrane transport GO:0034220 31 31 0,000 0,05279091 0,06587248 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! aging GO:0007568 32 31 0,000 0,05279091 0,06582791 ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,05279091 0,0657834 ! digestion GO:0007586 31 31 0,000 0,05279091 0,06573895 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,05279091 0,06569456 ! regulation of DNA replication GO:0006275 32 31 0,000 0,05279091 0,06565023 ! regulation of heart contraction GO:0008016 31 31 0,000 0,05279091 0,06560596 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,05279091 0,06556176 ! camera-type eye development GO:0043010 31 31 0,000 0,05279091 0,06551761 ! extracellular matrix organization GO:0030198 31 31 0,000 0,05279091 0,06547352 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,05279091 0,06542949 ! regulation of intracellular transport GO:0032386 31 31 0,000 0,05279091 0,06538551 ! regulation of myeloid cell differentiation GO:0045637 32 31 0,000 0,05279091 0,0653416 ! negative regulation of cell motion GO:0051271 31 31 0,000 0,05279091 0,06529775 ! negative regulation of cell growth GO:0030308 32 32 0,000 0,0544505 0,06730534 ! cell redox homeostasis GO:0045454 32 32 0,000 0,0544505 0,06726023 ! glucose catabolic process GO:0006007 32 32 0,000 0,0544505 0,06721518 ! lipid modification GO:0030258 32 32 0,000 0,0544505 0,06717019 ! regulation of phospholipase activity GO:0010517 32 32 0,000 0,0544505 0,06712526 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,0544505 0,06708039 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,0544505 0,06703558 ! cell maturation GO:0048469 32 32 0,000 0,0544505 0,06699083 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 0,000 0,0544505 0,06694614 ! morphogenesis of a branching structure GO:0001763 32 32 0,000 0,0544505 0,06690151 ! nuclear export GO:0051168 32 32 0,000 0,0544505 0,06685694 ! regulation of lymphocyte differentiation GO:0045619 32 32 0,000 0,0544505 0,06681243 ! kidney development GO:0001822 32 32 0,000 0,0544505 0,06676797 ! positive regulation of lipase activity GO:0060193 32 32 0,000 0,0544505 0,06672358 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,0544505 0,06667925 ! maintenance of location GO:0051235 33 32 0,000 0,0544505 0,06663497 ! negative regulation of cell size GO:0045792 33 33 0,000 0,05610742 0,0686171 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,05610742 0,0685716 ! amino acid transport GO:0006865 33 33 0,000 0,05610742 0,06852616 ! activation of protein kinase activity GO:0032147 35 33 0,000 0,05610742 0,06848077 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,05610742 0,06843545 ! regulation of neuron differentiation GO:0045664 34 33 0,000 0,05610742 0,06839019 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,05610742 0,06834499 ! regulation of angiogenesis GO:0045765 35 34 0,000 0,05776168 0,07031359 ! regulation of bone remodeling GO:0046850 34 34 0,000 0,05776168 0,07026717 ! response to metal ion GO:0010038 34 34 0,000 0,05776168 0,07022082 ! ear development GO:0043583 34 34 0,000 0,05776168 0,07017453 ! cellular polysaccharide metabolic process GO:0044264 35 34 0,000 0,05776168 0,07012831 ! regulation of protein catabolic process GO:0042176 35 34 0,000 0,05776168 0,07008214 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,05776168 0,07003603 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,05776168 0,06998999 ! regulation of lipid metabolic process GO:0019216 34 34 0,000 0,05776168 0,069944 ! secondary metabolic process GO:0019748 34 34 0,000 0,05776168 0,06989808 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,05776168 0,06985221 ! viral reproduction GO:0016032 34 34 0,000 0,05776168 0,06980641 ! detection of stimulus GO:0051606 36 34 0,000 0,05776168 0,06976066 ! acute inflammatory response GO:0002526 35 35 0,000 0,05941328 0,07170836 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,05941328 0,07166143 ! mesoderm development GO:0007498 35 35 0,000 0,05941328 0,07161456 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,05941328 0,07156776 GO:0048609|reproductive process in a multicellular organism, ! regulation of cell morphogenesis GO:0022604 38 35 0,000 0,05941328 0,07152101 ! positive regulation of phosphorylation GO:0042327 35 35 0,000 0,05941328 0,07147433 ! regulation of tissue remodeling GO:0034103 35 35 0,000 0,05941328 0,0714277 ! inorganic anion transport GO:0015698 35 35 0,000 0,05941328 0,07138114 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,05941328 0,07133464 ! regulation of immune effector process GO:0002697 35 35 0,000 0,05941328 0,0712882 ! hydrogen transport GO:0006818 36 36 0,000 0,06106222 0,07321905 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,06106222 0,07317144 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,06106222 0,0731239 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,06106222 0,07307641 ! regulation of mitosis GO:0007088 37 36 0,000 0,06106222 0,07302899 GO:0051783|regulation of nuclear division, ! positive regulation of cell migration GO:0030335 36 36 0,000 0,06106222 0,07298163 ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,06106222 0,07293433 GO:0035113|embryonic appendage morphogenesis, ! positive regulation of phosphorus metabolic process GO:0010562 36 36 0,000 0,06106222 0,0728871 GO:0045937|positive regulation of phosphate metabolic process, ! female pregnancy GO:0007565 37 36 0,000 0,06106222 0,07283992 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,06106222 0,07279281 ! positive regulation of organelle organization GO:0010638 36 36 0,000 0,06106222 0,07274575 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,06106222 0,07269876 ! integrin-mediated signaling pathway GO:0007229 36 36 0,000 0,06106222 0,07265183 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,06106222 0,07260495 ! gonad development GO:0008406 36 36 0,000 0,06106222 0,07255814 ! regulation of lipase activity GO:0060191 36 36 0,000 0,06106222 0,07251139 ! activation of immune response GO:0002253 36 36 0,000 0,06106222 0,0724647 ! coagulation GO:0050817 39 36 0,000 0,06106222 0,07241807 GO:0007596|blood coagulation, ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,06270852 0,0743227 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! regulation of transcription factor activity GO:0051090 38 37 0,000 0,06270852 0,07427494 GO:0090046|regulation of transcription regulator activity, ! meiosis GO:0007126 37 37 0,000 0,06270852 0,07422723 GO:0051327|M phase of meiotic cell cycle, ! response to drug GO:0042493 37 37 0,000 0,06270852 0,07417959 ! lung development GO:0030324 38 37 0,000 0,06270852 0,07413201 ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,06270852 0,07408449 ! eye development GO:0001654 37 37 0,000 0,06270852 0,07403703 ! negative regulation of growth GO:0045926 37 37 0,000 0,06270852 0,07398963 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,06270852 0,07394229 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,06270852 0,07389501 ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,06270852 0,0738478 ! adaptive immune response GO:0002250 37 37 0,000 0,06270852 0,07380064 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of secretion GO:0051047 39 38 0,000 0,06435217 0,07568669 ! neurotransmitter transport GO:0006836 40 38 0,000 0,06435217 0,07563842 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,06435217 0,07559022 ! exocytosis GO:0006887 40 38 0,000 0,06435217 0,07554207 ! cell-matrix adhesion GO:0007160 39 38 0,000 0,06435217 0,07549398 ! chromosome segregation GO:0007059 38 38 0,000 0,06435217 0,07544596 ! urogenital system development GO:0001655 38 38 0,000 0,06435217 0,075398 ! hexose catabolic process GO:0019320 38 38 0,000 0,06435217 0,07535009 ! RNA elongation GO:0006354 38 38 0,000 0,06435217 0,07530225 ! meiotic cell cycle GO:0051321 38 38 0,000 0,06435217 0,07525447 ! axon guidance GO:0007411 39 38 0,000 0,06435217 0,07520675 ! regulation of neurological system process GO:0031644 38 38 0,000 0,06435217 0,07515909 ! steroid hormone receptor signaling pathway GO:0030518 38 38 0,000 0,06435217 0,07511149 ! regulation of homeostatic process GO:0032844 38 38 0,000 0,06435217 0,07506396 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,06599318 0,07692943 ! hemostasis GO:0007599 42 39 0,000 0,06599318 0,0768808 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,06599318 0,07683223 ! activation of MAPK activity GO:0000187 39 39 0,000 0,06599318 0,07678373 ! respiratory tube development GO:0030323 40 39 0,000 0,06599318 0,07673528 ! response to unfolded protein GO:0006986 39 39 0,000 0,06599318 0,0766869 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,06599318 0,07663858 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,06599318 0,07659032 ! nucleotide-excision repair GO:0006289 40 39 0,000 0,06599318 0,07654212 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,06599318 0,07649398 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,06599318 0,0764459 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,06599318 0,07639788 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,06599318 0,07634992 ! respiratory system development GO:0060541 40 39 0,000 0,06599318 0,07630202 ! developmental maturation GO:0021700 39 39 0,000 0,06599318 0,07625419 ! lymphocyte differentiation GO:0030098 39 39 0,000 0,06599318 0,07620641 ! limb development GO:0060173 39 39 0,000 0,06599318 0,07615869 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! protein oligomerization GO:0051259 39 39 0,000 0,06599318 0,07611103 ! positive regulation of cell motion GO:0051272 39 39 0,000 0,06599318 0,07606343 ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,06763155 0,07790309 ! DNA catabolic process GO:0006308 41 40 0,000 0,06763155 0,07785443 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 0,000 0,06763155 0,07780583 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,06763155 0,07775729 ! organelle localization GO:0051640 41 40 0,000 0,06763155 0,07770882 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,06926728 0,07953869 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! cell cycle checkpoint GO:0000075 42 41 0,000 0,06926728 0,07948916 ! amine catabolic process GO:0009310 42 41 0,000 0,06926728 0,0794397 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,06926728 0,0793903 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,06926728 0,07934096 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,06926728 0,07929168 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,06926728 0,07924246 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,06926728 0,0791933 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,07090038 0,08101017 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,07090038 0,08095998 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,07090038 0,08090985 ! cell-substrate adhesion GO:0031589 43 42 0,000 0,07090038 0,08085978 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,07090038 0,08080978 ! protein ubiquitination GO:0016567 43 42 0,000 0,07090038 0,08075983 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,07090038 0,08070995 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! response to protein stimulus GO:0051789 42 42 0,000 0,07090038 0,08066013 ! forebrain development GO:0030900 43 42 0,000 0,07090038 0,08061037 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,07090038 0,08056067 ! reproductive structure development GO:0048608 43 43 0,000 0,07253086 0,08236252 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,07253086 0,08231181 ! alcohol catabolic process GO:0046164 43 43 0,000 0,07253086 0,08226115 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,07253086 0,08221056 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,07253086 0,08216003 ! humoral immune response GO:0006959 44 44 0,000 0,07415871 0,0839524 ! mRNA transport GO:0051028 44 44 0,000 0,07415871 0,08390086 ! protein import into nucleus GO:0006606 44 44 0,000 0,07415871 0,08384939 ! vitamin metabolic process GO:0006766 44 44 0,000 0,07415871 0,08379798 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,07415871 0,08374663 ! amine biosynthetic process GO:0009309 46 45 0,000 0,07578395 0,08552959 ! homophilic cell adhesion GO:0007156 45 45 0,000 0,07578395 0,08547724 ! regulation of DNA binding GO:0051101 47 45 0,000 0,07578395 0,08542496 ! phosphoinositide-mediated signaling GO:0048015 45 45 0,000 0,07578395 0,08537275 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,07578395 0,08532059 ! nuclear import GO:0051170 45 45 0,000 0,07578395 0,08526851 ! Wnt receptor signaling pathway GO:0016055 46 45 0,000 0,07578395 0,08521648 ! protein processing GO:0016485 45 45 0,000 0,07578395 0,08516452 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,07740656 0,08693498 ! tube morphogenesis GO:0035239 47 46 0,000 0,07740656 0,08688203 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,07740656 0,08682915 ! regulation of membrane potential GO:0042391 46 46 0,000 0,07740656 0,08677634 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,07902657 0,08853858 ! regulation of blood pressure GO:0008217 48 47 0,000 0,07902657 0,08848479 ! sex differentiation GO:0007548 47 47 0,000 0,07902657 0,08843107 ! amine transport GO:0015837 47 47 0,000 0,07902657 0,08837741 ! rhythmic process GO:0048511 47 47 0,000 0,07902657 0,08832381 ! regulation of catabolic process GO:0009894 48 47 0,000 0,07902657 0,08827028 ! calcium ion transport GO:0006816 48 48 0,000 0,08064397 0,09002231 ! regulation of cell cycle process GO:0010564 50 48 0,000 0,08064397 0,08996782 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,08064397 0,08991339 ! protein localization in nucleus GO:0034504 48 48 0,000 0,08064397 0,08985903 ! DNA recombination GO:0006310 48 48 0,000 0,08064397 0,08980473 ! leukocyte differentiation GO:0002521 50 49 0,000 0,08225876 0,09154764 ! ossification GO:0001503 50 49 0,000 0,08225876 0,09149239 GO:0060348|bone development, ! gland development GO:0048732 51 49 0,000 0,08225876 0,09143721 ! cell cycle arrest GO:0007050 49 49 0,000 0,08225876 0,0913821 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,08225876 0,09132705 ! divalent metal ion transport GO:0070838 49 49 0,000 0,08225876 0,09127206 ! response to nutrient GO:0007584 49 49 0,000 0,08225876 0,09121715 ! response to bacterium GO:0009617 50 49 0,000 0,08225876 0,0911623 ! positive regulation of MAP kinase activity GO:0043406 50 49 0,000 0,08225876 0,09110751 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,08225876 0,09105279 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,08225876 0,09099814 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,08387096 0,09272596 ! regulation of DNA metabolic process GO:0051052 51 50 0,000 0,08387096 0,09267037 ! negative regulation of transport GO:0051051 51 50 0,000 0,08387096 0,09261484 ! chromatin assembly GO:0031497 50 50 0,000 0,08387096 0,09255938 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,08387096 0,09250399 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! T cell activation GO:0042110 51 50 0,000 0,08387096 0,09244867 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 0,000 0,08387096 0,09239341 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,08387096 0,09233821 ! regulation of neurogenesis GO:0050767 51 50 0,000 0,08387096 0,09228309 ! transcription initiation GO:0006352 50 50 0,000 0,08387096 0,09222803 ! anatomical structure homeostasis GO:0060249 51 50 0,000 0,08387096 0,09217303 ! anterior/posterior pattern formation GO:0009952 51 50 0,000 0,08387096 0,0921181 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,08548055 0,09383005 ! protein modification by small protein conjugation GO:0032446 52 51 0,000 0,08548055 0,0937742 ! positive regulation of immune response GO:0050778 51 51 0,000 0,08548055 0,09371842 ! rRNA metabolic process GO:0016072 51 51 0,000 0,08548055 0,0936627 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,08548055 0,09360705 ! interphase of mitotic cell cycle GO:0051329 52 51 0,000 0,08548055 0,09355146 GO:0051325|interphase, ! ATP biosynthetic process GO:0006754 51 51 0,000 0,08548055 0,09349594 ! protein maturation GO:0051604 51 51 0,000 0,08548055 0,09344049 ! RNA localization GO:0006403 52 52 0,000 0,08708756 0,0951407 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,08708756 0,09508434 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 0,000 0,08708756 0,09502804 ! cell fate commitment GO:0045165 52 52 0,000 0,08708756 0,09497182 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,08708756 0,09491565 ! regulation of body fluid levels GO:0050878 55 52 0,000 0,08708756 0,09485956 ! response to light stimulus GO:0009416 53 52 0,000 0,08708756 0,09480353 ! sodium ion transport GO:0006814 53 53 0,000 0,08869197 0,0964931 ! tRNA metabolic process GO:0006399 53 53 0,000 0,08869197 0,09643617 ! response to hypoxia GO:0001666 53 53 0,000 0,08869197 0,09637931 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,08869197 0,09632251 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,08869197 0,09626579 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,08869197 0,09620913 ! regulation of T cell activation GO:0050863 53 53 0,000 0,08869197 0,09615253 ! regulation of protein transport GO:0051223 53 53 0,000 0,08869197 0,09609601 GO:0070201|regulation of establishment of protein localization, ! protein amino acid dephosphorylation GO:0006470 55 54 0,000 0,0902938 0,09777408 ! response to oxygen levels GO:0070482 55 54 0,000 0,0902938 0,09771666 ! response to virus GO:0009615 54 54 0,000 0,0902938 0,09765932 ! hormone metabolic process GO:0042445 55 54 0,000 0,0902938 0,09760204 ! sulfur metabolic process GO:0006790 55 54 0,000 0,0902938 0,09754483 ! negative regulation of multicellular organismal process GO:0051241 55 54 0,000 0,0902938 0,09748769 ! nucleosome organization GO:0034728 55 55 0,000 0,09189305 0,09915626 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,09189305 0,09909824 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! microtubule cytoskeleton organization GO:0000226 55 55 0,000 0,09189305 0,09904029 ! in utero embryonic development GO:0001701 55 55 0,000 0,09189305 0,09898241 ! regulation of cell adhesion GO:0030155 56 55 0,000 0,09189305 0,09892459 ! protein modification by small protein conjugation or removal GO:0070647 56 55 0,000 0,09189305 0,09886684 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,09348972 0,100526 ! reproductive developmental process GO:0003006 56 56 0,000 0,09348972 0,10046738 ! extracellular structure organization GO:0043062 56 56 0,000 0,09348972 0,10040884 ! regulation of nervous system development GO:0051960 57 56 0,000 0,09348972 0,10035036 ! ATP metabolic process GO:0046034 57 57 0,000 0,09508382 0,10200203 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,09508382 0,10194269 ! regulation of protein localization GO:0032880 58 57 0,000 0,09508382 0,10188342 ! innate immune response GO:0045087 58 58 0,000 0,09667535 0,10352857 ! dephosphorylation GO:0016311 60 59 0,000 0,09826431 0,10516906 ! carboxylic acid transport GO:0046942 59 59 0,000 0,09826431 0,10510802 GO:0015849|organic acid transport, ! peptidyl-amino acid modification GO:0018193 61 59 0,000 0,09826431 0,10504706 ! regulation of cell development GO:0060284 60 59 0,000 0,09826431 0,10498616 ! sterol metabolic process GO:0016125 59 59 0,000 0,09826431 0,10492533 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,09826431 0,10486458 ! protein localization in organelle GO:0033365 59 59 0,000 0,09826431 0,10480389 ! immune effector process GO:0002252 59 59 0,000 0,09826431 0,10474328 ! potassium ion transport GO:0006813 60 60 0,000 0,09985071 0,10637275 ! protein polymerization GO:0051258 65 60 0,000 0,09985071 0,1063113 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 0,000 0,10143455 0,10793526 ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,10143455 0,10787298 GO:0016054|organic acid catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,10143455 0,10781077 ! lipid transport GO:0006869 62 62 0,000 0,10301584 0,10942835 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,10301584 0,10936531 ! morphogenesis of an epithelium GO:0002009 63 62 0,000 0,10301584 0,10930235 GO:0060429|epithelium development, ! axonogenesis GO:0007409 66 62 0,000 0,10301584 0,10923946 ! protein import GO:0017038 62 62 0,000 0,10301584 0,10917664 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,10301584 0,1091139 ! regulation of lymphocyte activation GO:0051249 62 62 0,000 0,10301584 0,10905123 ! regulation of secretion GO:0051046 65 63 0,000 0,10459457 0,11065889 ! glucose metabolic process GO:0006006 63 63 0,000 0,10459457 0,11059541 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,10459457 0,11053199 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,10459457 0,11046865 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,10617076 0,11206913 ! regulation of response to external stimulus GO:0032101 65 64 0,000 0,10617076 0,11200498 ! angiogenesis GO:0001525 65 64 0,000 0,10617076 0,11194091 ! positive regulation of protein metabolic process GO:0051247 64 64 0,000 0,10617076 0,1118769 ! anion transport GO:0006820 65 65 0,000 0,1077444 0,11347025 ! positive regulation of cellular component organization GO:0051130 65 65 0,000 0,1077444 0,11340544 ! regulation of hormone levels GO:0010817 66 65 0,000 0,1077444 0,11334071 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,1093155 0,11492782 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,1093155 0,1148623 ! DNA packaging GO:0006323 66 66 0,000 0,1093155 0,11479685 ! regulation of MAP kinase activity GO:0043405 67 66 0,000 0,1093155 0,11473148 ! polysaccharide metabolic process GO:0005976 69 66 0,000 0,1093155 0,11466618 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 0,000 0,11088407 0,11624536 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! Golgi vesicle transport GO:0048193 67 67 0,000 0,11088407 0,11617927 ! negative regulation of cell differentiation GO:0045596 68 67 0,000 0,11088407 0,11611326 ! response to radiation GO:0009314 70 68 0,000 0,1124501 0,11768628 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,1124501 0,11761949 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,1124501 0,11755277 ! regulation of translation GO:0006417 69 69 0,000 0,11401361 0,11911966 ! sensory perception of sound GO:0007605 71 69 0,000 0,11401361 0,11905217 GO:0050954|sensory perception of mechanical stimulus, ! regionalization GO:0003002 70 69 0,000 0,11401361 0,11898476 ! response to nutrient levels GO:0031667 69 69 0,000 0,11401361 0,11891742 ! regulation of leukocyte activation GO:0002694 69 69 0,000 0,11401361 0,11885016 ! regulation of mitotic cell cycle GO:0007346 72 69 0,000 0,11401361 0,11878297 ! positive regulation of transport GO:0051050 71 70 0,000 0,11557459 0,12034123 ! cell part morphogenesis GO:0032990 75 70 0,000 0,11557459 0,12027327 ! wound healing GO:0042060 74 70 0,000 0,11557459 0,1202054 ! growth GO:0040007 70 70 0,000 0,11557459 0,1201376 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,11557459 0,12006988 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,11713305 0,1216204 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,11713305 0,12155192 ! regulation of cell migration GO:0030334 71 71 0,000 0,11713305 0,12148352 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,11713305 0,12141519 GO:0006874|cellular calcium ion homeostasis, ! ribosome biogenesis GO:0042254 71 71 0,000 0,11713305 0,12134694 ! regulation of cell activation GO:0050865 71 71 0,000 0,11713305 0,12127877 ! secretion by cell GO:0032940 75 72 0,000 0,11868899 0,12282078 ! sensory organ development GO:0007423 72 72 0,000 0,11868899 0,12275186 ! response to extracellular stimulus GO:0009991 72 72 0,000 0,11868899 0,12268301 ! regulation of cytokine production GO:0001817 72 72 0,000 0,11868899 0,12261424 ! electron transport chain GO:0022900 75 74 0,000 0,12179333 0,12575076 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,12179333 0,12568036 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,12334174 0,12720696 ! response to oxidative stress GO:0006979 76 75 0,000 0,12334174 0,12713581 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,12334174 0,12706475 ! positive regulation of multicellular organismal process GO:0051240 76 76 0,000 0,12488765 0,12858544 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,12643106 0,13010187 ! cell morphogenesis involved in differentiation GO:0000904 82 77 0,000 0,12643106 0,13002926 ! regulation of protein modification process GO:0031399 79 78 0,000 0,12797197 0,13154063 ! microtubule-based movement GO:0007018 82 78 0,000 0,12797197 0,1314673 ! positive regulation of protein kinase cascade GO:0010740 79 78 0,000 0,12797197 0,13139406 ! metal ion homeostasis GO:0055065 78 78 0,000 0,12797197 0,1313209 ! regulation of immune response GO:0050776 78 78 0,000 0,12797197 0,13124783 ! regulation of locomotion GO:0040012 79 79 0,000 0,12951039 0,13275175 ! nuclear transport GO:0051169 79 79 0,000 0,12951039 0,13267796 GO:0006913|nucleocytoplasmic transport, ! regulation of cell motion GO:0051270 79 79 0,000 0,12951039 0,13260425 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,13104632 0,13410237 ! neuron projection development GO:0031175 85 80 0,000 0,13104632 0,13402796 ! MAPKKK cascade GO:0000165 82 81 0,000 0,13257977 0,13552109 ! tube development GO:0035295 83 81 0,000 0,13257977 0,13544596 ! lymphocyte activation GO:0046649 82 81 0,000 0,13257977 0,13537093 ! lipid catabolic process GO:0016042 82 81 0,000 0,13257977 0,13529597 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,13563923 0,1383415 ! ncRNA processing GO:0034470 83 83 0,000 0,13563923 0,13826499 ! blood vessel morphogenesis GO:0048514 84 83 0,000 0,13563923 0,13818856 ! cellular amino acid derivative metabolic process GO:0006575 87 84 0,000 0,13716524 0,13966605 ! regulation of cellular localization GO:0060341 86 85 0,000 0,13868879 0,14113939 ! nitrogen compound biosynthetic process GO:0044271 86 85 0,000 0,13868879 0,1410615 ! positive regulation of cell differentiation GO:0045597 87 85 0,000 0,13868879 0,1409837 ! positive regulation of response to stimulus GO:0048584 86 85 0,000 0,13868879 0,14090598 ! positive regulation of protein kinase activity GO:0045860 89 86 0,000 0,14020987 0,14237289 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 0,000 0,14020987 0,14229449 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,14020987 0,14221617 GO:0006644|phospholipid metabolic process, ! hexose metabolic process GO:0019318 87 86 0,000 0,14020987 0,14213795 ! male gamete generation GO:0048232 90 88 0,000 0,14324464 0,14513462 GO:0007283|spermatogenesis, ! positive regulation of transferase activity GO:0051347 91 88 0,000 0,14324464 0,14505488 GO:0033674|positive regulation of kinase activity, ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,14324464 0,14497522 ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 0,000 0,14475835 0,1464268 ! regulation of Ras protein signal transduction GO:0046578 90 90 0,000 0,1462696 0,14787431 ! brain development GO:0007420 91 90 0,000 0,1462696 0,14779324 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 0,000 0,1477784 0,14923594 ! DNA replication GO:0006260 91 91 0,000 0,1477784 0,14915421 ! visual perception GO:0007601 93 92 0,000 0,14928475 0,15059212 GO:0050953|sensory perception of light stimulus, ! fatty acid metabolic process GO:0006631 93 92 0,000 0,14928475 0,15050974 ! positive regulation of immune system process GO:0002684 92 92 0,000 0,14928475 0,15042745 ! tissue morphogenesis GO:0048729 94 93 0,000 0,15078867 0,15185985 ! regulation of response to stress GO:0080134 97 94 0,000 0,15229015 0,15328823 ! blood vessel development GO:0001568 95 94 0,000 0,15229015 0,15320456 ! pattern specification process GO:0007389 96 94 0,000 0,15229015 0,15312097 ! cofactor metabolic process GO:0051186 95 94 0,000 0,15229015 0,15303748 ! vasculature development GO:0001944 97 96 0,000 0,15528581 0,1559628 ! endocytosis GO:0006897 99 98 0,000 0,15827176 0,15887519 GO:0010324|membrane invagination, ! posttranscriptional regulation of gene expression GO:0010608 98 98 0,000 0,15827176 0,15878871 ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,15827176 0,15870232 ! blood circulation GO:0008015 99 98 0,000 0,15827176 0,15861602 GO:0003013|circulatory system process, ! regulation of system process GO:0044057 98 98 0,000 0,15827176 0,15852981 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 0,000 0,16124804 0,16142321 ! response to other organism GO:0051707 101 100 0,000 0,16124804 0,16133558 ! hemopoiesis GO:0030097 104 100 0,000 0,16124804 0,16124804