pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/6712-8-real-Parker_GPL887-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/GPL887.an.zip classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! induction of apoptosis by intracellular signals GO:0008629 56 41 3,000 1,153E-07 4,208E-04 ! release of cytochrome c from mitochondria GO:0001836 26 14 2,000 4,393E-07 8,014E-04 ! protein serine/threonine kinase inhibitor activity GO:0030291 17 16 2,000 6,749E-07 8,207E-04 ! apoptotic mitochondrial changes GO:0008637 33 21 2,000 1,597E-06 1,457E-03 ! protein kinase inhibitor activity GO:0004860 37 34 2,000 7,119E-06 5,194E-03 ! kinase inhibitor activity GO:0019210 47 35 2,000 7,781E-06 4,731E-03 ! muscle thin filament assembly GO:0030240 5 5 1,000 1,196E-05 6,234E-03 ! lymphocyte apoptosis GO:0070227 6 5 1,000 1,196E-05 5,454E-03 ! RNA polymerase II carboxy-terminal domain kinase activity GO:0008353 5 5 1,000 1,196E-05 4,848E-03 ! epidermal growth factor receptor binding GO:0005154 7 5 1,000 1,196E-05 4,363E-03 ! skeletal myofibril assembly GO:0014866 6 6 1,000 1,793E-05 5,946E-03 ! SAP kinase activity GO:0016909 7 6 1,000 1,793E-05 5,451E-03 ! regulation of protein homodimerization activity GO:0043496 9 6 1,000 1,793E-05 5,031E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 55 51 2,000 2,447E-05 6,377E-03 ! insulin receptor substrate binding GO:0043560 10 7 1,000 2,508E-05 6,101E-03 ! negative regulation of survival gene product expression GO:0008634 9 7 1,000 2,508E-05 5,719E-03 ! activation of caspase activity by cytochrome c GO:0008635 7 7 1,000 2,508E-05 5,383E-03 ! mitochondrion morphogenesis GO:0070584 9 7 1,000 2,508E-05 5,084E-03 ! cyclin-dependent protein kinase holoenzyme complex GO:0000307 8 8 1,000 3,342E-05 6,417E-03 ! keratinocyte proliferation GO:0043616 9 8 1,000 3,342E-05 6,096E-03 ! regulation of caspase activity GO:0043281 78 60 2,000 3,996E-05 6,941E-03 ! spectrin GO:0008091 9 9 1,000 4,294E-05 7,121E-03 ! regulation of endopeptidase activity GO:0052548 81 63 2,000 4,627E-05 7,338E-03 ! negative regulation of protein kinase activity GO:0006469 78 64 2,000 4,851E-05 7,373E-03 ! negative regulation of kinase activity GO:0033673 79 65 2,000 5,082E-05 7,415E-03 ! protein kinase regulator activity GO:0019887 74 66 2,000 5,32E-05 7,464E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 12 10 1,000 5,364E-05 7,248E-03 ! regulation of mitochondrial membrane potential GO:0051881 11 10 1,000 5,364E-05 6,989E-03 ! positive regulation of neuron apoptosis GO:0043525 11 10 1,000 5,364E-05 6,748E-03 ! MAP kinase kinase activity GO:0004708 12 10 1,000 5,364E-05 6,523E-03 ! cyclin-dependent protein kinase inhibitor activity GO:0004861 10 10 1,000 5,364E-05 6,313E-03 ! regulation of peptidase activity GO:0052547 86 67 2,000 5,565E-05 6,344E-03 ! negative regulation of transferase activity GO:0051348 85 70 2,000 6,346E-05 7,015E-03 ! cell cortex GO:0005938 77 70 2,000 6,346E-05 6,808E-03 ! positive regulation of B cell proliferation GO:0030890 15 11 1,000 6,552E-05 6,829E-03 ! protein serine/threonine/tyrosine kinase activity GO:0004712 13 11 1,000 6,552E-05 6,639E-03 ! negative regulation of caspase activity GO:0043154 12 11 1,000 6,552E-05 6,46E-03 ! structural constituent of cytoskeleton GO:0005200 78 72 2,000 6,904E-05 6,627E-03 ! midbody GO:0030496 14 12 1,000 7,857E-05 7,349E-03 ! kinase regulator activity GO:0019207 93 76 2,000 8,114E-05 7,4E-03 ! striated muscle thin filament GO:0005865 14 13 1,000 9,279E-05 8,256E-03 ! organelle fusion GO:0048284 16 13 1,000 9,279E-05 8,06E-03 ! ADP binding GO:0043531 15 13 1,000 9,279E-05 7,872E-03 ! mitochondrion organization GO:0007005 104 82 2,000 1,018E-04 8,438E-03 ! negative regulation of peptidase activity GO:0010466 16 14 1,000 1,082E-04 8,77E-03 ! positive regulation of cell growth GO:0030307 15 14 1,000 1,082E-04 8,58E-03 ! regulation of B cell proliferation GO:0030888 18 14 1,000 1,082E-04 8,397E-03 ! MAP kinase activity GO:0004707 16 14 1,000 1,082E-04 8,222E-03 ! cyclin-dependent protein kinase regulator activity GO:0016538 14 14 1,000 1,082E-04 8,054E-03 ! actin filament bundle GO:0032432 18 15 1,000 1,247E-04 9,102E-03 GO:0001725|stress fiber, ! myofibril assembly GO:0030239 17 16 1,000 1,425E-04 0,01019089 GO:0055002|striated muscle cell development, ! G2/M transition of mitotic cell cycle GO:0000086 22 16 1,000 1,425E-04 9,995E-03 ! myosin binding GO:0017022 17 16 1,000 1,425E-04 9,806E-03 ! DNA fragmentation involved in apoptosis GO:0006309 18 16 1,000 1,425E-04 9,625E-03 ! Ras protein signal transduction GO:0007265 118 93 2,000 1,48E-04 9,813E-03 ! skin development GO:0043588 20 17 1,000 1,614E-04 0,01051134 ! positive regulation of cell size GO:0045793 19 18 1,000 1,814E-04 0,01160994 ! spindle microtubule GO:0005876 27 18 1,000 1,814E-04 0,01140977 ! actomyosin GO:0042641 21 18 1,000 1,814E-04 0,01121638 ! muscle cell development GO:0055001 20 18 1,000 1,814E-04 0,01102944 ! regulation of survival gene product expression GO:0045884 23 19 1,000 2,026E-04 0,01211674 ! positive regulation of fibroblast proliferation GO:0048146 25 19 1,000 2,026E-04 0,01192131 ! cell structure disassembly during apoptosis GO:0006921 31 20 1,000 2,25E-04 0,01302683 ! apoptotic nuclear changes GO:0030262 24 21 1,000 2,485E-04 0,01416353 ! regulation of protein binding GO:0043393 25 21 1,000 2,485E-04 0,01394563 ! negative regulation of Wnt receptor signaling pathway GO:0030178 22 21 1,000 2,485E-04 0,01373433 ! cortical actin cytoskeleton GO:0030864 21 21 1,000 2,485E-04 0,01352934 ! actomyosin structure organization GO:0031032 24 22 1,000 2,731E-04 0,0146535 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 33 22 1,000 2,731E-04 0,01444113 ! barbed-end actin filament capping GO:0051016 24 22 1,000 2,731E-04 0,01423483 GO:0051693|actin filament capping, ! positive regulation of B cell activation GO:0050871 26 22 1,000 2,731E-04 0,01403434 ! DNA catabolic process, endonucleolytic GO:0000737 24 22 1,000 2,731E-04 0,01383942 ! cellular component assembly involved in morphogenesis GO:0010927 23 22 1,000 2,731E-04 0,01364984 ! actin filament GO:0005884 26 24 1,000 3,259E-04 0,01606676 ! negative regulation of actin filament depolymerization GO:0030835 26 24 1,000 3,259E-04 0,01585253 ! small nuclear ribonucleoprotein complex GO:0030532 24 24 1,000 3,259E-04 0,01564395 ! negative regulation of actin filament polymerization GO:0030837 36 25 1,000 3,54E-04 0,01677211 ! epidermal growth factor receptor signaling pathway GO:0007173 32 26 1,000 3,833E-04 0,01792471 ! negative regulation of protein polymerization GO:0032272 37 26 1,000 3,833E-04 0,01769782 ! regulation of fibroblast proliferation GO:0048145 32 26 1,000 3,833E-04 0,0174766 ! regulation of actin filament depolymerization GO:0030834 28 26 1,000 3,833E-04 0,01726084 ! insulin receptor signaling pathway GO:0008286 34 26 1,000 3,833E-04 0,01705034 ! spliceosomal snRNP biogenesis GO:0000387 29 27 1,000 4,136E-04 0,01818021 ! cyclin-dependent protein kinase activity GO:0004693 28 27 1,000 4,136E-04 0,01796378 ! negative regulation of protein complex assembly GO:0031333 39 28 1,000 4,452E-04 0,01910509 ! negative regulation of phosphorylation GO:0042326 30 28 1,000 4,452E-04 0,01888293 ! striated muscle cell differentiation GO:0051146 42 29 1,000 4,778E-04 0,020035 ! cortical cytoskeleton GO:0030863 33 30 1,000 5,116E-04 0,02120779 ! response to toxin GO:0009636 33 30 1,000 5,116E-04 0,0209695 ! negative regulation of phosphorus metabolic process GO:0010563 34 31 1,000 5,465E-04 0,02215163 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of Wnt receptor signaling pathway GO:0030111 36 33 1,000 6,197E-04 0,0248428 ! negative regulation of hydrolase activity GO:0051346 36 34 1,000 6,58E-04 0,02609093 ! regulation of B cell activation GO:0050864 40 34 1,000 6,58E-04 0,02581038 ! nucleus organization GO:0006997 42 36 1,000 7,379E-04 0,02863782 ! cellular response to extracellular stimulus GO:0031668 37 36 1,000 7,379E-04 0,02833637 ! positive regulation of mast cell proliferation GO:0070668 43 36 1,000 7,379E-04 0,0280412 GO:0050671|positive regulation of lymphocyte proliferation, ! skeletal muscle fiber development GO:0048741 41 37 1,000 7,796E-04 0,02931813 ! positive regulation of leukocyte proliferation GO:0070665 47 37 1,000 7,796E-04 0,02901897 GO:0032946|positive regulation of mononuclear cell proliferation, ! negative regulation of protein complex disassembly GO:0043242 42 38 1,000 8,223E-04 0,03030124 ! muscle fiber development GO:0048747 42 38 1,000 8,223E-04 0,02999823 ! cellular response to insulin stimulus GO:0032869 47 38 1,000 8,223E-04 0,02970121 ! induction of apoptosis by extracellular signals GO:0008624 44 39 1,000 8,662E-04 0,03097881 ! regulation of actin filament polymerization GO:0030833 53 40 1,000 9,112E-04 0,03227087 ! lamellipodium GO:0030027 56 41 1,000 9,572E-04 0,03357687 ! positive regulation of growth GO:0045927 47 43 1,000 1,053E-03 0,0365739 ! G1/S transition of mitotic cell cycle GO:0000082 54 43 1,000 1,053E-03 0,03622886 ! activation of caspase activity GO:0006919 60 43 1,000 1,053E-03 0,03589028 ! ruffle GO:0001726 50 44 1,000 1,102E-03 0,03722603 ! regulation of neuron apoptosis GO:0043523 58 44 1,000 1,102E-03 0,03688451 ! membrane fusion GO:0006944 52 44 1,000 1,102E-03 0,0365492 ! regulation of protein complex disassembly GO:0043244 49 45 1,000 1,153E-03 0,03787897 ! response to UV GO:0009411 59 45 1,000 1,153E-03 0,03754076 ! SH3/SH2 adaptor activity GO:0005070 52 46 1,000 1,204E-03 0,03887357 ! regulation of actin polymerization or depolymerization GO:0008064 60 47 1,000 1,257E-03 0,04021795 ! regulation of protein polymerization GO:0032271 60 47 1,000 1,257E-03 0,03986823 ! response to insulin stimulus GO:0032868 57 47 1,000 1,257E-03 0,03952454 ! protein homooligomerization GO:0051260 63 48 1,000 1,311E-03 0,04086288 ! positive regulation of caspase activity GO:0043280 65 48 1,000 1,311E-03 0,04051658 GO:0010952|positive regulation of peptidase activity, ! growth factor receptor binding GO:0070851 58 48 1,000 1,311E-03 0,04017611 ! protein N-terminus binding GO:0047485 57 48 1,000 1,311E-03 0,03984131 ! cell cortex part GO:0044448 54 48 1,000 1,311E-03 0,03951204 ! regulation of actin filament length GO:0030832 62 49 1,000 1,365E-03 0,04082816 ! negative regulation of cytoskeleton organization GO:0051494 73 49 1,000 1,365E-03 0,04049623 ! regulation of mast cell proliferation GO:0070666 57 49 1,000 1,365E-03 0,04016964 ! DNA damage response, signal transduction GO:0042770 84 50 1,000 1,421E-03 0,0414806 ! regulation of cellular component size GO:0032535 66 52 1,000 1,536E-03 0,04448415 ! regulation of lymphocyte proliferation GO:0050670 61 52 1,000 1,536E-03 0,04413388 ! cellular component disassembly GO:0022411 69 52 1,000 1,536E-03 0,04378908 ! keratinocyte differentiation GO:0030216 60 53 1,000 1,596E-03 0,04512305 ! DNA catabolic process GO:0006308 57 53 1,000 1,596E-03 0,04477595 ! regulation of leukocyte proliferation GO:0070663 65 53 1,000 1,596E-03 0,04443415 GO:0032944|regulation of mononuclear cell proliferation, ! regulation of protein complex assembly GO:0043254 67 54 1,000 1,656E-03 0,04576267 ! epidermal cell differentiation GO:0009913 66 58 1,000 1,908E-03 0,05232313 ! receptor signaling protein serine/threonine kinase activity GO:0004702 64 58 1,000 1,908E-03 0,05193266 ! muscle cell differentiation GO:0042692 77 59 1,000 1,973E-03 0,05332066 ! actin filament organization GO:0007015 65 59 1,000 1,973E-03 0,0529286 ! molecular adaptor activity GO:0060090 73 60 1,000 2,04E-03 0,05431737 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 77 62 1,000 2,176E-03 0,05753234 ! negative regulation of cell growth GO:0030308 69 63 1,000 2,246E-03 0,05895137 ! regulation of actin cytoskeleton organization GO:0032956 93 64 1,000 2,317E-03 0,06037759 ! negative regulation of cell size GO:0045792 71 65 1,000 2,389E-03 0,06181079 ! positive regulation of lymphocyte activation GO:0051251 83 65 1,000 2,389E-03 0,0613755 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 80 65 1,000 2,389E-03 0,06094631 ! response to peptide hormone stimulus GO:0043434 79 67 1,000 2,536E-03 0,06424806 ! regulation of actin filament-based process GO:0032970 96 67 1,000 2,536E-03 0,06380497 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 83 67 1,000 2,536E-03 0,06336795 ! negative regulation of organelle organization GO:0010639 93 68 1,000 2,611E-03 0,06480031 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 84 68 1,000 2,611E-03 0,06436247 ! sarcomere GO:0030017 74 69 1,000 2,687E-03 0,06579446 ! skeletal muscle tissue development GO:0007519 75 69 1,000 2,687E-03 0,06535583 GO:0060538|skeletal muscle organ development, ! positive regulation of ligase activity GO:0051351 86 70 1,000 2,765E-03 0,06678742 ! mitochondrial outer membrane GO:0005741 81 71 1,000 2,843E-03 0,0682251 ! pore complex GO:0046930 89 72 1,000 2,922E-03 0,0696687 ! positive regulation of leukocyte activation GO:0002696 92 73 1,000 3,002E-03 0,07111806 ! positive regulation of cell activation GO:0050867 94 75 1,000 3,166E-03 0,07451101 ! regulation of ubiquitin-protein ligase activity GO:0051438 92 75 1,000 3,166E-03 0,07403338 ! neuropeptide signaling pathway GO:0007218 85 76 1,000 3,249E-03 0,07549903 ! negative regulation of growth GO:0045926 85 76 1,000 3,249E-03 0,07502119 ! cell leading edge GO:0031252 97 76 1,000 3,249E-03 0,07454936 ! myofibril GO:0030016 82 77 1,000 3,334E-03 0,07600769 ! protein oligomerization GO:0051259 93 77 1,000 3,334E-03 0,07553559 ! regulation of ligase activity GO:0051340 95 78 1,000 3,419E-03 0,07699287 ! contractile fiber part GO:0044449 83 78 1,000 3,419E-03 0,07652052 ! cellular response to hormone stimulus GO:0032870 94 79 1,000 3,506E-03 0,07797674 ! interphase of mitotic cell cycle GO:0051329 100 81 1,000 3,681E-03 0,081394 ! cellular respiration GO:0045333 85 82 1,000 3,771E-03 0,08287035 ! interphase GO:0051325 103 83 1,000 3,861E-03 0,08435113 ! contractile fiber GO:0043292 88 83 1,000 3,861E-03 0,08384904 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 101 83 1,000 3,861E-03 0,0833529 GO:0010498|proteasomal protein catabolic process, ! regulation of membrane potential GO:0042391 98 83 1,000 3,861E-03 0,08286259 ! protein binding, bridging GO:0030674 104 85 1,000 4,046E-03 0,08630417 ! organelle outer membrane GO:0031968 102 88 1,000 4,329E-03 0,0918173 ! outer membrane GO:0019867 104 90 1,000 4,523E-03 0,09537879 ! spindle GO:0005819 126 92 1,000 4,721E-03 0,09898281 ! regulation of cellular component biogenesis GO:0044087 115 92 1,000 4,721E-03 0,09841719 ! cell cycle arrest GO:0007050 103 93 1,000 4,822E-03 0,09994133 ! regulation of cytoskeleton organization GO:0051493 133 93 1,000 4,822E-03 0,09937669 ! homophilic cell adhesion GO:0007156 107 95 1,000 5,026E-03 0,10299899 ! negative regulation of cellular component organization GO:0051129 132 99 1,000 5,445E-03 0,1109785 ! regulation of lymphocyte activation GO:0051249 123 100 1,000 5,553E-03 0,11253837 ! response to light stimulus GO:0009416 131 100 1,000 5,553E-03 0,11191661 ! positive regulation of epidermal growth factor receptor activity GO:0045741 6 5 0,000 5,597E-03 0,11218604 ! negative regulation of S phase of mitotic cell cycle GO:0045749 5 5 0,000 5,597E-03 0,111573 ! positive regulation of fatty acid biosynthetic process GO:0045723 5 5 0,000 5,597E-03 0,11096663 ! positive regulation of tumor necrosis factor biosynthetic process GO:0042535 6 5 0,000 5,597E-03 0,11036681 ! response to superoxide GO:0000303 5 5 0,000 5,597E-03 0,10977344 ! negative regulation of small GTPase mediated signal transduction GO:0051058 6 5 0,000 5,597E-03 0,10918641 GO:0046580|negative regulation of Ras protein signal transduction, ! regulation of interferon-alpha production GO:0032647 6 5 0,000 5,597E-03 0,10860563 GO:0032479|regulation of type I interferon production, ! regulation of hormone biosynthetic process GO:0046885 5 5 0,000 5,597E-03 0,108031 ! calcium:cation antiporter activity GO:0015368 5 5 0,000 5,597E-03 0,10746242 ! quinolinate metabolic process GO:0046874 5 5 0,000 5,597E-03 0,10689979 ! biotin binding GO:0009374 7 5 0,000 5,597E-03 0,10634302 ! secondary active monocarboxylate transmembrane transporter activity GO:0015355 6 5 0,000 5,597E-03 0,10579202 ! tongue development GO:0043586 6 5 0,000 5,597E-03 0,1052467 ! nose development GO:0043584 5 5 0,000 5,597E-03 0,10470697 ! cell proliferation in forebrain GO:0021846 5 5 0,000 5,597E-03 0,10417275 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 5 5 0,000 5,597E-03 0,10364396 ! sodium-dependent phosphate transmembrane transporter activity GO:0015321 6 5 0,000 5,597E-03 0,1031205 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 7 5 0,000 5,597E-03 0,10260231 ! drug:hydrogen antiporter activity GO:0015307 6 5 0,000 5,597E-03 0,1020893 GO:0015520|tetracycline:hydrogen antiporter activity, GO:0015904|tetracycline transport, ! nuclear mRNA 3'-splice site recognition GO:0000389 6 5 0,000 5,597E-03 0,10158139 ! glycolipid transport GO:0046836 6 5 0,000 5,597E-03 0,10107851 ! phospholipid:diacylglycerol acyltransferase activity GO:0046027 6 5 0,000 5,597E-03 0,10058059 ! regulation of respiratory gaseous exchange GO:0043576 6 5 0,000 5,597E-03 0,10008755 ! regulation of protein export from nucleus GO:0046825 5 5 0,000 5,597E-03 0,09959931 ! neuron adhesion GO:0007158 5 5 0,000 5,597E-03 0,09911582 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 5 5 0,000 5,597E-03 0,098637 ! transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer GO:0046912 6 5 0,000 5,597E-03 0,09816278 ! opioid peptide activity GO:0001515 6 5 0,000 5,597E-03 0,09769311 ! selenocysteine incorporation GO:0001514 5 5 0,000 5,597E-03 0,0972279 GO:0006451|translational readthrough, ! mRNA stabilization GO:0048255 6 5 0,000 5,597E-03 0,09676711 GO:0043489|RNA stabilization, ! N-acetylglucosamine 6-O-sulfotransferase activity GO:0001517 8 5 0,000 5,597E-03 0,09631066 ! cardiac muscle cell proliferation GO:0060038 6 5 0,000 5,597E-03 0,09585849 GO:0014855|striated muscle cell proliferation, ! dsRNA fragmentation GO:0031050 6 5 0,000 5,597E-03 0,09541056 GO:0035196|gene silencing by miRNA, production of miRNAs, GO:0035195|gene silencing by miRNA, ! ruffle membrane GO:0032587 6 5 0,000 5,597E-03 0,09496679 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 5,597E-03 0,09452713 ! negative regulation of receptor-mediated endocytosis GO:0048261 7 5 0,000 5,597E-03 0,09409152 ! clathrin coat assembly GO:0048268 6 5 0,000 5,597E-03 0,0936599 ! cerebral cortex cell migration GO:0021795 5 5 0,000 5,597E-03 0,09323223 ! eukaryotic translation elongation factor 1 complex GO:0005853 5 5 0,000 5,597E-03 0,09280845 ! membrane hyperpolarization GO:0060081 5 5 0,000 5,597E-03 0,0923885 ! regulation of striated muscle cell differentiation GO:0051153 6 5 0,000 5,597E-03 0,09197234 ! regulation of smooth muscle cell differentiation GO:0051150 5 5 0,000 5,597E-03 0,09155991 ! translation repressor activity GO:0030371 8 5 0,000 5,597E-03 0,09115116 ! positive regulation of muscle cell differentiation GO:0051149 6 5 0,000 5,597E-03 0,09074604 ! smooth muscle cell differentiation GO:0051145 6 5 0,000 5,597E-03 0,09034451 ! chaperone-mediated protein complex assembly GO:0051131 5 5 0,000 5,597E-03 0,08994652 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 5 5 0,000 5,597E-03 0,08955201 ! negative regulation of stress-activated protein kinase signaling pathway GO:0070303 6 5 0,000 5,597E-03 0,08916096 GO:0046329|negative regulation of JNK cascade, ! double-stranded telomeric DNA binding GO:0003691 6 5 0,000 5,597E-03 0,0887733 ! negative regulation of heart contraction GO:0045822 5 5 0,000 5,597E-03 0,088389 ! N-acetylgalactosamine 4-O-sulfotransferase activity GO:0001537 5 5 0,000 5,597E-03 0,08800801 ! microfibril GO:0001527 5 5 0,000 5,597E-03 0,0876303 ! troponin I binding GO:0031013 5 5 0,000 5,597E-03 0,08725581 ! negative regulation of viral genome replication GO:0045071 6 5 0,000 5,597E-03 0,08688451 ! traversing start control point of mitotic cell cycle GO:0007089 6 5 0,000 5,597E-03 0,08651635 ! positive regulation of interleukin-12 biosynthetic process GO:0045084 5 5 0,000 5,597E-03 0,0861513 ! dorsal/ventral neural tube patterning GO:0021904 5 5 0,000 5,597E-03 0,08578932 ! dermatan sulfate proteoglycan metabolic process GO:0050655 5 5 0,000 5,597E-03 0,08543037 ! protein lipoylation GO:0009249 14 5 0,000 5,597E-03 0,08507441 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 5,597E-03 0,08472141 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 5 5 0,000 5,597E-03 0,08437132 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! regulation of isotype switching to IgG isotypes GO:0048302 5 5 0,000 5,597E-03 0,08402411 ! transmembrane-ephrin receptor activity GO:0005005 6 5 0,000 5,597E-03 0,08367975 ! mitochondrion localization, microtubule-mediated GO:0034643 5 5 0,000 5,597E-03 0,0833382 GO:0047497|mitochondrion transport along microtubule, GO:0051654|establishment of mitochondrion localization, ! vasopressin receptor activity GO:0005000 5 5 0,000 5,597E-03 0,08299943 ! glutamate catabolic process GO:0006538 6 5 0,000 5,597E-03 0,0826634 ! microvillus organization GO:0032528 5 5 0,000 5,597E-03 0,08233008 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 6 5 0,000 5,597E-03 0,08199943 ! tyrosine catabolic process GO:0006572 5 5 0,000 5,597E-03 0,08167144 ! response to pH GO:0009268 5 5 0,000 5,597E-03 0,08134605 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 6 5 0,000 5,597E-03 0,08102325 ! regulation of protein import into nucleus, translocation GO:0033158 5 5 0,000 5,597E-03 0,080703 ! oxidoreductase activity, acting on sulfur group of donors, oxygen as acceptor GO:0016670 5 5 0,000 5,597E-03 0,08038527 ! polyol biosynthetic process GO:0046173 5 5 0,000 5,597E-03 0,08007004 ! phosphatidylinositol-4,5-bisphosphate 3-kinase activity GO:0046934 7 5 0,000 5,597E-03 0,07975726 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 5,597E-03 0,07944692 ! fibroblast growth factor receptor activity GO:0005007 6 5 0,000 5,597E-03 0,07913899 ! protein-DNA loading ATPase activity GO:0033170 6 5 0,000 5,597E-03 0,07883343 GO:0003689|DNA clamp loader activity, ! mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) GO:0000276 5 5 0,000 5,597E-03 0,07853023 ! anaerobic glycolysis GO:0019642 5 5 0,000 5,597E-03 0,07822935 GO:0004459|L-lactate dehydrogenase activity, ! adenosine receptor activity, G-protein coupled GO:0001609 6 5 0,000 5,597E-03 0,07793076 ! regulation of retinoic acid receptor signaling pathway GO:0048385 6 5 0,000 5,597E-03 0,07763445 ! peroxisomal matrix GO:0005782 5 5 0,000 5,597E-03 0,07734038 GO:0031907|microbody lumen, ! regulation of angiotensin levels in blood GO:0002002 5 5 0,000 5,597E-03 0,07704853 GO:0060177|regulation of angiotensin metabolic process, ! vacuolar lumen GO:0005775 6 5 0,000 5,597E-03 0,07675887 ! morphogenesis of an epithelial sheet GO:0002011 5 5 0,000 5,597E-03 0,07647138 ! multivesicular body GO:0005771 5 5 0,000 5,597E-03 0,07618604 ! regulation of phospholipase A2 activity GO:0032429 5 5 0,000 5,597E-03 0,07590282 GO:0032430|positive regulation of phospholipase A2 activity, ! paraxial mesoderm formation GO:0048341 6 5 0,000 5,597E-03 0,0756217 ! insulin-like growth factor I binding GO:0031994 6 5 0,000 5,597E-03 0,07534265 ! mitochondrial outer membrane translocase complex GO:0005742 5 5 0,000 5,597E-03 0,07506566 ! peptidyl-histidine phosphorylation GO:0018106 6 5 0,000 5,597E-03 0,07479069 ! negative regulation of lipoprotein lipase activity GO:0051005 5 5 0,000 5,597E-03 0,07451773 ! epithelial cell maturation GO:0002070 14 5 0,000 5,597E-03 0,07424676 ! positive regulation of lipoprotein lipase activity GO:0051006 6 5 0,000 5,597E-03 0,07397775 ! regulation of protein amino acid autophosphorylation GO:0031952 5 5 0,000 5,597E-03 0,07371068 ! nitric-oxide synthase regulator activity GO:0030235 6 5 0,000 5,597E-03 0,07344554 ! negative regulation of fatty acid metabolic process GO:0045922 14 5 0,000 5,597E-03 0,07318229 ! regulation of glycoprotein biosynthetic process GO:0010559 6 5 0,000 5,597E-03 0,07292093 ! cellular glucose homeostasis GO:0001678 5 5 0,000 5,597E-03 0,07266142 ! positive regulation of translational initiation GO:0045948 6 5 0,000 5,597E-03 0,07240376 ! nonhomologous end joining complex GO:0070419 6 5 0,000 5,597E-03 0,07214791 GO:0005958|DNA-dependent protein kinase-DNA ligase 4 complex, ! depyrimidination GO:0045008 5 5 0,000 5,597E-03 0,07189387 ! regulation of chromatin assembly or disassembly GO:0001672 5 5 0,000 5,597E-03 0,07164161 ! ATPase activator activity GO:0001671 5 5 0,000 5,597E-03 0,07139112 ! phosphoinositide 5-phosphatase activity GO:0034595 5 5 0,000 5,597E-03 0,07114237 GO:0004439|phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity, ! DNA damage response, signal transduction resulting in transcription GO:0042772 17 5 0,000 5,597E-03 0,07089534 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! calcium sensitive guanylate cyclase activator activity GO:0008048 5 5 0,000 5,597E-03 0,07065003 ! regulation of cholesterol biosynthetic process GO:0045540 5 5 0,000 5,597E-03 0,07040641 ! positive regulation of collagen metabolic process GO:0010714 6 5 0,000 5,597E-03 0,07016446 GO:0032967|positive regulation of collagen biosynthetic process, ! phosphatidylinositol N-acetylglucosaminyltransferase activity GO:0017176 7 5 0,000 5,597E-03 0,06992418 ! regulation of protein amino acid dephosphorylation GO:0035304 7 5 0,000 5,597E-03 0,06968553 ! cardiac myofibril assembly GO:0055003 5 5 0,000 5,597E-03 0,0694485 ! anterograde axon cargo transport GO:0008089 6 5 0,000 5,597E-03 0,06921308 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 5,597E-03 0,06897925 ! GPI-anchor transamidase complex GO:0042765 5 5 0,000 5,597E-03 0,068747 GO:0003923|GPI-anchor transamidase activity, ! regulation of leukocyte degranulation GO:0043300 5 5 0,000 5,597E-03 0,06851631 ! thiamin and derivative metabolic process GO:0042723 5 5 0,000 5,597E-03 0,06828715 ! protein localization to telomere GO:0070198 7 5 0,000 5,597E-03 0,06805953 ! response to exogenous dsRNA GO:0043330 5 5 0,000 5,597E-03 0,06783342 ! MutSalpha complex binding GO:0032407 7 5 0,000 5,597E-03 0,06760881 ! bile acid biosynthetic process GO:0006699 5 5 0,000 5,597E-03 0,06738567 ! negative regulation of fat cell differentiation GO:0045599 6 5 0,000 5,597E-03 0,06716401 ! enucleate erythrocyte differentiation GO:0043353 7 5 0,000 5,597E-03 0,0669438 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 5,597E-03 0,06672503 ! nerve growth factor binding GO:0048406 7 5 0,000 5,597E-03 0,06650768 ! platelet-derived growth factor binding GO:0048407 8 5 0,000 5,597E-03 0,06629175 ! high-density lipoprotein binding GO:0008035 6 5 0,000 5,597E-03 0,06607721 ! negative regulation of focal adhesion formation GO:0051895 5 5 0,000 5,597E-03 0,06586406 ! transcription initiation factor activity GO:0016986 5 5 0,000 5,597E-03 0,06565228 ! gas homeostasis GO:0033483 5 5 0,000 5,597E-03 0,06544186 ! Schwann cell development GO:0014044 5 5 0,000 5,597E-03 0,06523278 ! CD4-positive, alpha beta T cell differentiation GO:0043367 5 5 0,000 5,597E-03 0,06502503 ! cyclohydrolase activity GO:0019238 5 5 0,000 5,597E-03 0,0648186 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 5,597E-03 0,06461348 ! response to pheromone GO:0019236 5 5 0,000 5,597E-03 0,06440965 GO:0016503|pheromone receptor activity, ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 5 5 0,000 5,597E-03 0,0642071 ! phosphatidylserine metabolic process GO:0006658 5 5 0,000 5,597E-03 0,06400583 ! rhombomere development GO:0021546 6 5 0,000 5,597E-03 0,06380581 ! alanine transport GO:0032328 6 5 0,000 5,597E-03 0,06360704 ! superoxide-generating NADPH oxidase activity GO:0016175 5 5 0,000 5,597E-03 0,0634095 ! NAD(P)H oxidase activity GO:0016174 5 5 0,000 5,597E-03 0,06321319 ! ventral spinal cord interneuron specification GO:0021521 7 5 0,000 5,597E-03 0,06301808 GO:0021514|ventral spinal cord interneuron differentiation, GO:0060579|ventral spinal cord interneuron fate commitment, ! spinal cord motor neuron cell fate specification GO:0021520 6 5 0,000 5,597E-03 0,06282418 ! regulation of meiosis GO:0040020 6 5 0,000 5,597E-03 0,06263147 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 6 5 0,000 5,597E-03 0,06243994 GO:0000085|G2 phase of mitotic cell cycle, ! parasympathetic nervous system development GO:0048486 5 5 0,000 5,597E-03 0,06224957 ! lymphocyte costimulation GO:0031294 5 5 0,000 5,597E-03 0,06206036 GO:0031295|T cell costimulation, ! response to tumor cell GO:0002347 7 5 0,000 5,597E-03 0,0618723 ! RS domain binding GO:0050733 6 5 0,000 5,597E-03 0,06168538 ! telomerase holoenzyme complex GO:0005697 6 5 0,000 5,597E-03 0,06149958 ! negative regulation of lipoprotein metabolic process GO:0050748 6 5 0,000 5,597E-03 0,06131489 ! B cell homeostasis GO:0001782 6 5 0,000 5,597E-03 0,06113132 ! positive regulation of Wnt receptor signaling pathway GO:0030177 5 5 0,000 5,597E-03 0,06094883 ! anaphase GO:0051322 7 5 0,000 5,597E-03 0,06076744 GO:0000090|mitotic anaphase, ! S phase GO:0051320 5 5 0,000 5,597E-03 0,06058712 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of blood coagulation GO:0030194 6 5 0,000 5,597E-03 0,06040787 GO:0050820|positive regulation of coagulation, ! ribonuclease H activity GO:0004523 14 5 0,000 5,597E-03 0,06022967 ! AP-2 adaptor complex GO:0030122 5 5 0,000 5,597E-03 0,06005253 GO:0030128|clathrin coat of endocytic vesicle, ! lipase activator activity GO:0060229 6 5 0,000 5,597E-03 0,05987642 ! diuresis GO:0030146 5 5 0,000 5,597E-03 0,05970134 GO:0030147|natriuresis, ! phosphatidylcholine binding GO:0031210 5 5 0,000 5,597E-03 0,05952729 ! DNA-methyltransferase activity GO:0009008 5 5 0,000 5,597E-03 0,05935424 ! structural constituent of nuclear pore GO:0017056 5 5 0,000 5,597E-03 0,0591822 ! very-low-density lipoprotein particle clearance GO:0034447 6 5 0,000 5,597E-03 0,05901115 ! GTP-Rho binding GO:0017049 5 5 0,000 5,597E-03 0,05884109 ! glucocorticoid biosynthetic process GO:0006704 5 5 0,000 5,597E-03 0,05867201 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 5,597E-03 0,05850389 ! chondroitin sulfotransferase activity GO:0034481 6 5 0,000 5,597E-03 0,05833674 ! brown fat cell differentiation GO:0050873 5 5 0,000 5,597E-03 0,05817054 ! regulation of telomerase activity GO:0051972 6 5 0,000 5,597E-03 0,05800528 ! quaternary ammonium group transmembrane transporter activity GO:0015651 5 5 0,000 5,597E-03 0,05784096 ! TAP complex GO:0042825 5 5 0,000 5,597E-03 0,05767757 ! platelet dense granule GO:0042827 6 5 0,000 5,597E-03 0,0575151 ! bHLH transcription factor binding GO:0043425 5 5 0,000 5,597E-03 0,05735354 ! secretory granule organization GO:0033363 5 5 0,000 5,597E-03 0,05719288 ! endodeoxyribonuclease activity, producing 5'-phosphomonoesters GO:0016888 14 5 0,000 5,597E-03 0,05703313 ! ligase activity, forming phosphoric ester bonds GO:0016886 5 5 0,000 5,597E-03 0,05687426 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 5,597E-03 0,05671628 ! lamin binding GO:0005521 8 5 0,000 5,597E-03 0,05655917 ! aldehyde-lyase activity GO:0016832 6 5 0,000 5,597E-03 0,05640293 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 5,597E-03 0,05624755 ! neural plate morphogenesis GO:0001839 6 5 0,000 5,597E-03 0,05609302 ! cyclosporin A binding GO:0016018 6 5 0,000 5,597E-03 0,05593934 ! peptidoglycan receptor activity GO:0016019 5 5 0,000 5,597E-03 0,0557865 ! negative regulation of fibrinolysis GO:0051918 5 5 0,000 5,597E-03 0,05563449 ! positive regulation of telomere maintenance GO:0032206 7 5 0,000 5,597E-03 0,05548331 ! pattern recognition receptor signaling pathway GO:0002221 5 5 0,000 5,597E-03 0,05533295 GO:0002224|toll-like receptor signaling pathway, ! phosphatidylinositol-3,4,5-trisphosphate binding GO:0005547 5 5 0,000 5,597E-03 0,0551834 ! positive regulation of blood vessel endothelial cell migration GO:0043536 6 5 0,000 5,597E-03 0,05503466 ! flavin-containing monooxygenase activity GO:0004499 6 5 0,000 5,597E-03 0,05488672 ! regulation of calcium ion transport via store-operated calcium channel activity GO:0032234 5 5 0,000 5,597E-03 0,05473957 ! hemopoietic progenitor cell differentiation GO:0002244 6 5 0,000 5,597E-03 0,05459321 ! organ or tissue specific immune response GO:0002251 6 5 0,000 5,597E-03 0,05444762 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 7 5 0,000 5,597E-03 0,05430282 ! retina homeostasis GO:0001895 5 5 0,000 5,597E-03 0,05415878 ! prepulse inhibition GO:0060134 8 5 0,000 5,597E-03 0,0540155 ! maternal placenta development GO:0001893 5 5 0,000 5,597E-03 0,05387298 GO:0046697|decidualization, ! endothelial cell development GO:0001885 6 5 0,000 5,597E-03 0,05373121 ! regulation of growth hormone secretion GO:0060123 5 5 0,000 5,597E-03 0,05359018 GO:0060124|positive regulation of growth hormone secretion, ! isocitrate dehydrogenase activity GO:0004448 5 5 0,000 5,597E-03 0,05344989 ! thiamin pyrophosphate binding GO:0030976 5 5 0,000 5,597E-03 0,05331034 ! protein palmitoylation GO:0018345 5 5 0,000 5,597E-03 0,05317151 ! protein amino acid prenylation GO:0018346 6 5 0,000 5,597E-03 0,0530334 ! N-methyl-D-aspartate selective glutamate receptor complex GO:0017146 8 5 0,000 5,597E-03 0,05289601 ! stem cell division GO:0017145 6 5 0,000 5,597E-03 0,05275933 GO:0048103|somatic stem cell division, ! fibroblast growth factor binding GO:0017134 5 5 0,000 5,597E-03 0,05262335 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 6 5 0,000 5,597E-03 0,05248807 ! organ regeneration GO:0031100 6 5 0,000 5,597E-03 0,05235349 ! positive regulation of microtubule polymerization GO:0031116 5 5 0,000 5,597E-03 0,05221959 ! negative regulation of nucleotide biosynthetic process GO:0030809 6 5 0,000 5,597E-03 0,05208638 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of developmental growth GO:0048639 6 5 0,000 5,597E-03 0,05195384 ! acyl carrier activity GO:0000036 5 5 0,000 5,597E-03 0,05182198 ! positive regulation of cAMP biosynthetic process GO:0030819 6 5 0,000 5,597E-03 0,05169078 GO:0030816|positive regulation of cAMP metabolic process, ! condensin complex GO:0000796 6 5 0,000 5,597E-03 0,05156025 ! phagocytic vesicle GO:0045335 5 5 0,000 5,597E-03 0,05143038 ! blood coagulation, extrinsic pathway GO:0007598 5 5 0,000 5,597E-03 0,05130115 ! regulation of cGMP biosynthetic process GO:0030826 5 5 0,000 5,597E-03 0,05117258 GO:0030823|regulation of cGMP metabolic process, ! citrulline metabolic process GO:0000052 14 5 0,000 5,597E-03 0,05104465 ! positive regulation of actin filament polymerization GO:0030838 5 5 0,000 5,597E-03 0,05091735 ! polyol transport GO:0015791 8 5 0,000 5,597E-03 0,05079069 ! post-embryonic morphogenesis GO:0009886 7 5 0,000 5,597E-03 0,05066466 ! pyrimidine nucleotide-sugar transport GO:0015781 5 5 0,000 5,597E-03 0,05053926 ! regulation of cell adhesion mediated by integrin GO:0033628 5 5 0,000 5,597E-03 0,05041447 ! cell adhesion mediated by integrin GO:0033627 5 5 0,000 5,597E-03 0,05029029 ! short-chain fatty acid metabolic process GO:0046459 6 5 0,000 5,597E-03 0,05016673 ! glycerol-3-phosphate metabolic process GO:0006072 6 5 0,000 5,597E-03 0,05004377 ! ethanol metabolic process GO:0006067 6 5 0,000 5,597E-03 0,04992142 GO:0006069|ethanol oxidation, GO:0034308|monohydric alcohol metabolic process, ! phosphatidic acid metabolic process GO:0046473 5 5 0,000 5,597E-03 0,04979966 ! cobalt ion transport GO:0006824 5 5 0,000 5,597E-03 0,04967849 ! cellular zinc ion homeostasis GO:0006882 6 5 0,000 5,597E-03 0,04955791 ! Golgi to plasma membrane transport GO:0006893 7 5 0,000 5,597E-03 0,04943792 ! syncytium formation by plasma membrane fusion GO:0000768 5 5 0,000 5,597E-03 0,0493185 GO:0007520|myoblast fusion, ! poly(U) RNA binding GO:0008266 5 5 0,000 5,597E-03 0,04919966 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 5 5 0,000 5,597E-03 0,04908139 ! sterol carrier activity GO:0005498 6 5 0,000 5,597E-03 0,04896369 ! adaptation of signaling pathway GO:0022401 6 5 0,000 5,597E-03 0,04884655 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! 2-oxoglutarate metabolic process GO:0006103 6 5 0,000 5,597E-03 0,04872997 ! response to acid GO:0001101 7 5 0,000 5,597E-03 0,04861395 ! fibril organization GO:0043206 5 5 0,000 5,597E-03 0,04849848 ! malate metabolic process GO:0006108 6 5 0,000 5,597E-03 0,04838355 ! regulation of dopamine uptake GO:0051584 7 5 0,000 5,597E-03 0,04826917 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! copulation GO:0007620 5 5 0,000 5,597E-03 0,04815533 ! circadian sleep/wake cycle process GO:0022410 5 5 0,000 5,597E-03 0,04804202 GO:0042749|regulation of circadian sleep/wake cycle, GO:0045187|regulation of circadian sleep/wake cycle, sleep, ! cleavage furrow GO:0032154 6 5 0,000 5,597E-03 0,04792925 ! protein maturation by protein folding GO:0022417 5 5 0,000 5,597E-03 0,047817 ! activation of protein kinase B activity GO:0032148 15 5 0,000 5,597E-03 0,04770528 ! origin recognition complex GO:0000808 5 5 0,000 5,597E-03 0,04759408 ! neurexin binding GO:0042043 6 5 0,000 5,597E-03 0,04748339 ! sensory perception of temperature stimulus GO:0050951 8 5 0,000 5,597E-03 0,04737322 ! protein amino acid dealkylation GO:0008214 5 5 0,000 5,597E-03 0,04726356 GO:0006482|protein amino acid demethylation, ! NF-kappaB-inducing kinase activity GO:0004704 5 5 0,000 5,597E-03 0,04715441 ! lipoic acid binding GO:0031405 5 5 0,000 5,597E-03 0,04704576 ! very-low-density lipoprotein particle assembly GO:0034379 5 5 0,000 5,597E-03 0,04693761 ! lithium ion binding GO:0031403 6 5 0,000 5,597E-03 0,04682995 ! grooming behavior GO:0007625 7 5 0,000 5,597E-03 0,04672279 ! regulation of smooth muscle cell apoptosis GO:0034391 5 5 0,000 5,597E-03 0,04661612 ! ribose phosphate diphosphokinase activity GO:0004749 6 5 0,000 5,597E-03 0,04650993 ! lymph vessel development GO:0001945 6 5 0,000 5,597E-03 0,04640423 ! bicarbonate transport GO:0015701 5 5 0,000 5,597E-03 0,046299 ! positive regulation of cell-matrix adhesion GO:0001954 8 5 0,000 5,597E-03 0,04619425 GO:0010811|positive regulation of cell-substrate adhesion, ! response to interferon-gamma GO:0034341 6 5 0,000 5,597E-03 0,04608998 ! protein-lysine 6-oxidase activity GO:0004720 23 5 0,000 5,597E-03 0,04598617 ! endothelial cell proliferation GO:0001935 8 5 0,000 5,597E-03 0,04588283 ! polynucleotide adenylyltransferase activity GO:0004652 5 5 0,000 5,597E-03 0,04577995 ! dorsal spinal cord development GO:0021516 6 5 0,000 5,597E-03 0,04567754 ! activation of MAPKKK activity GO:0000185 5 5 0,000 5,597E-03 0,04557558 ! synaptic vesicle maturation GO:0016188 6 5 0,000 5,597E-03 0,04547407 ! sphingoid catabolic process GO:0046521 5 5 0,000 5,597E-03 0,04537302 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 5 5 0,000 5,597E-03 0,04527242 ! neutrophil mediated immunity GO:0002446 5 5 0,000 5,597E-03 0,04517225 ! intercellular canaliculus GO:0046581 5 5 0,000 5,597E-03 0,04507254 ! dopamine binding GO:0035240 7 5 0,000 5,597E-03 0,04497326 GO:0004952|dopamine receptor activity, ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 5 5 0,000 5,597E-03 0,04487442 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 5 5 0,000 5,597E-03 0,04477601 ! NAD(P)+-protein-arginine ADP-ribosyltransferase activity GO:0003956 6 5 0,000 5,597E-03 0,04467803 ! amine oxidase activity GO:0008131 7 5 0,000 5,597E-03 0,04458048 ! monocyte activation GO:0042117 9 5 0,000 5,597E-03 0,04448335 ! negative regulation of protein binding GO:0032091 5 5 0,000 5,597E-03 0,04438665 ! regulation of response to food GO:0032095 5 5 0,000 5,597E-03 0,04429037 ! response to food GO:0032094 6 5 0,000 5,597E-03 0,0441945 ! positive regulation of protein binding GO:0032092 5 5 0,000 5,597E-03 0,04409905 ! copper ion transmembrane transporter activity GO:0005375 5 5 0,000 5,597E-03 0,04400401 ! regulation of ryanodine-sensitive calcium-release channel activity GO:0060314 6 5 0,000 5,597E-03 0,04390937 ! hedgehog receptor activity GO:0008158 5 5 0,000 5,597E-03 0,04381515 ! lipoprotein catabolic process GO:0042159 5 5 0,000 5,597E-03 0,04372133 ! substrate-bound cell migration, cell extension GO:0006930 7 5 0,000 5,597E-03 0,0436279 ! purine salvage GO:0043101 7 5 0,000 5,597E-03 0,04353488 ! small-subunit processome GO:0032040 5 5 0,000 5,597E-03 0,04344225 ! positive regulation of catecholamine secretion GO:0033605 5 5 0,000 5,597E-03 0,04335002 ! ciliary rootlet GO:0035253 5 5 0,000 5,597E-03 0,04325818 ! myosin heavy chain binding GO:0032036 5 5 0,000 5,597E-03 0,04316672 ! nucleobase transport GO:0015851 5 5 0,000 5,597E-03 0,04307565 ! sodium ion transmembrane transporter activity GO:0015081 6 5 0,000 5,597E-03 0,04298497 ! GPI anchor binding GO:0034235 6 5 0,000 5,597E-03 0,04289466 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 5,597E-03 0,04280474 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! thrombin receptor activity GO:0015057 5 5 0,000 5,597E-03 0,04271519 ! palmitoyl-CoA hydrolase activity GO:0016290 5 5 0,000 5,597E-03 0,04262601 ! basic amino acid transport GO:0015802 5 5 0,000 5,597E-03 0,04253721 ! dendritic shaft GO:0043198 5 5 0,000 5,597E-03 0,04244877 ! terminal button GO:0043195 7 5 0,000 5,597E-03 0,0423607 ! arginine N-methyltransferase activity GO:0016273 6 5 0,000 5,597E-03 0,042273 GO:0016274|protein-arginine N-methyltransferase activity, ! neuronal ion channel clustering GO:0045161 5 5 0,000 5,597E-03 0,04218566 ! transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity GO:0030618 6 5 0,000 5,597E-03 0,04209868 ! homeostasis of number of cells within a tissue GO:0048873 7 5 0,000 5,597E-03 0,04201206 ! negative regulation of peptide secretion GO:0002792 5 5 0,000 5,597E-03 0,04192579 GO:0046676|negative regulation of insulin secretion, ! neural nucleus development GO:0048857 6 5 0,000 5,597E-03 0,04183988 ! response to UV-C GO:0010225 15 5 0,000 5,597E-03 0,04175431 ! positive regulation of organ growth GO:0046622 5 5 0,000 5,597E-03 0,0416691 ! response to arsenic GO:0046685 6 5 0,000 5,597E-03 0,04158423 ! IgE binding GO:0019863 5 5 0,000 5,597E-03 0,04149971 ! positive regulation of T cell cytokine production GO:0002726 5 5 0,000 5,597E-03 0,04141554 GO:0032743|positive regulation of interleukin-2 production, ! transcription-coupled nucleotide-excision repair GO:0006283 5 5 0,000 5,597E-03 0,0413317 ! monoamine transmembrane transporter activity GO:0008504 6 5 0,000 5,597E-03 0,0412482 ! response to copper ion GO:0046688 5 5 0,000 5,597E-03 0,04116504 ! response to cadmium ion GO:0046686 5 5 0,000 5,597E-03 0,04108221 ! tetrahydrofolate metabolic process GO:0046653 5 5 0,000 5,597E-03 0,04099972 ! regulation of interleukin-1 beta production GO:0032651 5 5 0,000 5,597E-03 0,04091755 ! protein autoprocessing GO:0016540 6 5 0,000 5,597E-03 0,04083572 ! intracellular cyclic nucleotide activated cation channel activity GO:0005221 5 5 0,000 5,597E-03 0,04075421 GO:0043855|cyclic nucleotide-gated ion channel activity, ! negative regulation of monooxygenase activity GO:0032769 5 5 0,000 5,597E-03 0,04067303 ! ryanodine-sensitive calcium-release channel activity GO:0005219 5 5 0,000 5,597E-03 0,04059217 GO:0005218|intracellular ligand-gated calcium channel activity, ! positive regulation of interleukin-10 production GO:0032733 5 5 0,000 5,597E-03 0,04051163 ! mitotic recombination GO:0006312 15 5 0,000 5,597E-03 0,0404314 ! negative regulation of interleukin-6 production GO:0032715 6 5 0,000 5,597E-03 0,0403515 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 5,597E-03 0,04027191 ! membrane to membrane docking GO:0022614 5 5 0,000 5,597E-03 0,04019264 ! regulation of transcription from RNA polymerase I promoter GO:0006356 14 5 0,000 5,597E-03 0,04011367 ! translation activator activity GO:0008494 5 5 0,000 5,597E-03 0,04003502 ! somatostatin receptor activity GO:0004994 5 5 0,000 5,597E-03 0,03995667 ! melanocortin receptor activity GO:0004977 6 5 0,000 5,597E-03 0,03987863 ! serine-type carboxypeptidase activity GO:0004185 5 5 0,000 5,597E-03 0,0398009 GO:0070008|serine-type exopeptidase activity, ! protein phosphatase 2A binding GO:0051721 6 5 0,000 5,597E-03 0,03972346 ! salivary gland morphogenesis GO:0007435 5 5 0,000 5,597E-03 0,03964633 ! galactosidase activity GO:0015925 5 5 0,000 5,597E-03 0,03956949 ! prostaglandin E receptor activity GO:0004957 7 5 0,000 5,597E-03 0,03949296 ! cellular response to nutrient GO:0031670 5 5 0,000 5,597E-03 0,03941672 ! ATP-dependent chromatin remodeling GO:0043044 5 5 0,000 5,597E-03 0,03934077 ! L-cystine transmembrane transporter activity GO:0015184 5 5 0,000 5,597E-03 0,03926511 ! glycine transmembrane transporter activity GO:0015187 7 5 0,000 5,597E-03 0,03918975 ! L-gamma-aminobutyric acid transmembrane transporter activity GO:0015185 6 5 0,000 5,597E-03 0,03911467 ! A band GO:0031672 5 5 0,000 5,597E-03 0,03903988 ! heat generation GO:0031649 5 5 0,000 5,597E-03 0,03896538 ! flagellum organization GO:0043064 5 5 0,000 5,597E-03 0,03889116 GO:0009296|flagellum assembly, ! tricarboxylic acid cycle enzyme complex GO:0045239 6 5 0,000 5,597E-03 0,03881722 ! disaccharide metabolic process GO:0005984 6 5 0,000 5,597E-03 0,03874357 ! glycogen catabolic process GO:0005980 16 5 0,000 5,597E-03 0,03867019 ! dopamine biosynthetic process GO:0042416 6 5 0,000 5,597E-03 0,03859709 ! 5'-3' exonuclease activity GO:0008409 14 5 0,000 5,597E-03 0,03852426 ! chromocenter GO:0010369 5 5 0,000 5,597E-03 0,03845171 ! glial cell migration GO:0008347 5 5 0,000 5,597E-03 0,03837943 ! calcium-dependent phospholipase A2 activity GO:0047498 5 5 0,000 5,597E-03 0,03830743 ! negative regulation of NF-kappaB import into nucleus GO:0042347 5 5 0,000 5,597E-03 0,03823569 ! growth hormone receptor binding GO:0005131 5 5 0,000 5,597E-03 0,03816422 ! protein serine/threonine phosphatase inhibitor activity GO:0004865 6 5 0,000 5,597E-03 0,03809302 ! negative regulation of smooth muscle contraction GO:0045986 7 5 0,000 5,597E-03 0,03802208 ! aminomethyltransferase activity GO:0004047 5 5 0,000 5,597E-03 0,03795141 ! aminoacylase activity GO:0004046 5 5 0,000 5,597E-03 0,037881 ! penetration of zona pellucida GO:0007341 6 5 0,000 5,597E-03 0,03781085 ! alcohol dehydrogenase activity, zinc-dependent GO:0004024 5 5 0,000 5,597E-03 0,03774096 ! nucleus localization GO:0051647 5 5 0,000 5,597E-03 0,03767133 ! 3-chloroallyl aldehyde dehydrogenase activity GO:0004028 5 5 0,000 5,597E-03 0,03760195 ! carnitine metabolic process GO:0009437 5 5 0,000 5,597E-03 0,03753283 GO:0006577|betaine metabolic process, ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 6,713E-03 0,04493275 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 6 6 0,000 6,713E-03 0,04485046 ! regulation of helicase activity GO:0051095 6 6 0,000 6,713E-03 0,04476846 ! response to oxygen radical GO:0000305 6 6 0,000 6,713E-03 0,04468677 ! positive regulation of axon extension GO:0045773 7 6 0,000 6,713E-03 0,04460537 ! forebrain neuron differentiation GO:0021879 6 6 0,000 6,713E-03 0,04452427 ! forebrain regionalization GO:0021871 7 6 0,000 6,713E-03 0,04444347 ! meiotic prophase I GO:0007128 7 6 0,000 6,713E-03 0,04436295 ! hydroxymethyl-, formyl- and related transferase activity GO:0016742 6 6 0,000 6,713E-03 0,04428273 ! inositol trisphosphate phosphatase activity GO:0046030 8 6 0,000 6,713E-03 0,0442028 GO:0004445|inositol-polyphosphate 5-phosphatase activity, ! regulation of lipid kinase activity GO:0043550 6 6 0,000 6,713E-03 0,04412315 ! SMAD protein nuclear translocation GO:0007184 7 6 0,000 6,713E-03 0,04404379 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 9 6 0,000 6,713E-03 0,04396472 ! carbohydrate phosphorylation GO:0046835 7 6 0,000 6,713E-03 0,04388593 ! phosphoinositide 3-kinase binding GO:0043548 6 6 0,000 6,713E-03 0,04380742 ! protein amino acid sulfation GO:0006477 9 6 0,000 6,713E-03 0,0437292 GO:0051923|sulfation, ! diphosphotransferase activity GO:0016778 7 6 0,000 6,713E-03 0,04365125 ! establishment of tissue polarity GO:0007164 8 6 0,000 6,713E-03 0,04357358 ! protein thiol-disulfide exchange GO:0006467 6 6 0,000 6,713E-03 0,04349618 ! receptor guanylyl cyclase signaling pathway GO:0007168 6 6 0,000 6,713E-03 0,04341906 ! embryonic camera-type eye development GO:0031076 9 6 0,000 6,713E-03 0,04334221 GO:0048596|embryonic camera-type eye morphogenesis, ! hexokinase activity GO:0004396 7 6 0,000 6,713E-03 0,04326564 ! regulation of mitochondrial membrane permeability GO:0046902 7 6 0,000 6,713E-03 0,04318933 ! neurofilament cytoskeleton organization GO:0060052 6 6 0,000 6,713E-03 0,04311329 ! Notch receptor processing GO:0007220 7 6 0,000 6,713E-03 0,04303752 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen GO:0016714 8 6 0,000 6,713E-03 0,04296202 ! oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water GO:0016717 7 6 0,000 6,713E-03 0,04288678 ! eukaryotic translation initiation factor 2B complex GO:0005851 6 6 0,000 6,713E-03 0,0428118 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 6 0,000 6,713E-03 0,04273708 ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 6 0,000 6,713E-03 0,04266263 ! neurofilament GO:0005883 7 6 0,000 6,713E-03 0,04258843 ! glial cell fate commitment GO:0021781 7 6 0,000 6,713E-03 0,0425145 ! cytoplasmic dynein complex GO:0005868 7 6 0,000 6,713E-03 0,04244081 ! dynactin complex GO:0005869 7 6 0,000 6,713E-03 0,04236739 ! fibroblast growth factor receptor antagonist activity GO:0030353 7 6 0,000 6,713E-03 0,04229421 GO:0005152|interleukin-1 receptor antagonist activity, ! enoyl-CoA hydratase activity GO:0004300 6 6 0,000 6,713E-03 0,04222129 ! oocyte maturation GO:0001556 6 6 0,000 6,713E-03 0,04214862 ! DNA replication origin binding GO:0003688 6 6 0,000 6,713E-03 0,0420762 ! reflex GO:0060004 10 6 0,000 6,713E-03 0,04200403 ! positive regulation of glycolysis GO:0045821 6 6 0,000 6,713E-03 0,04193211 ! parathyroid gland development GO:0060017 6 6 0,000 6,713E-03 0,04186043 ! anagen GO:0042640 7 6 0,000 6,713E-03 0,04178899 ! protein-cofactor linkage GO:0018065 15 6 0,000 6,713E-03 0,0417178 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 6 6 0,000 6,713E-03 0,04164685 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! protein targeting to ER GO:0045047 7 6 0,000 6,713E-03 0,04157615 GO:0006614|SRP-dependent cotranslational protein targeting to membrane, ! 3'-phosphoadenosine 5'-phosphosulfate binding GO:0050656 6 6 0,000 6,713E-03 0,04150568 ! structural constituent of tooth enamel GO:0030345 7 6 0,000 6,713E-03 0,04143545 ! cysteine metabolic process GO:0006534 7 6 0,000 6,713E-03 0,04136546 ! glycine catabolic process GO:0006546 6 6 0,000 6,713E-03 0,0412957 ! adenohypophysis development GO:0021984 6 6 0,000 6,713E-03 0,04122618 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 6 6 0,000 6,713E-03 0,04115689 ! deoxyribonucleotide biosynthetic process GO:0009263 7 6 0,000 6,713E-03 0,04108783 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 6 0,000 6,713E-03 0,04101901 ! microtubule nucleation GO:0007020 7 6 0,000 6,713E-03 0,04095042 ! proline biosynthetic process GO:0006561 8 6 0,000 6,713E-03 0,04088205 ! tryptophan metabolic process GO:0006568 6 6 0,000 6,713E-03 0,04081392 ! oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor GO:0016671 6 6 0,000 6,713E-03 0,04074601 ! thyroid hormone generation GO:0006590 6 6 0,000 6,713E-03 0,04067832 ! melanin biosynthetic process from tyrosine GO:0006583 7 6 0,000 6,713E-03 0,04061086 ! retinoid X receptor binding GO:0046965 7 6 0,000 6,713E-03 0,04054362 ! proton-transporting V-type ATPase, V0 domain GO:0033179 6 6 0,000 6,713E-03 0,04047661 ! transforming growth factor beta receptor activity, type I GO:0005025 7 6 0,000 6,713E-03 0,04040982 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 6,713E-03 0,04034324 ! sister chromatid cohesion GO:0007062 6 6 0,000 6,713E-03 0,04027689 ! retinoic acid receptor signaling pathway GO:0048384 9 6 0,000 6,713E-03 0,04021075 ! positive regulation of transporter activity GO:0032411 8 6 0,000 6,713E-03 0,04014484 GO:0032414|positive regulation of ion transmembrane transporter activity, ! cerebral cortex neuron differentiation GO:0021895 7 6 0,000 6,713E-03 0,04007913 ! regulation of fatty acid beta-oxidation GO:0031998 6 6 0,000 6,713E-03 0,04001364 ! p53 binding GO:0002039 6 6 0,000 6,713E-03 0,03994837 ! demethylase activity GO:0032451 6 6 0,000 6,713E-03 0,03988331 ! positive regulation of nitric-oxide synthase activity GO:0051000 6 6 0,000 6,713E-03 0,03981845 ! regulation of platelet activation GO:0010543 7 6 0,000 6,713E-03 0,03975381 ! lipid phosphatase activity GO:0042577 7 6 0,000 6,713E-03 0,03968938 ! lens morphogenesis in camera-type eye GO:0002089 6 6 0,000 6,713E-03 0,03962516 ! guanylate cyclase activator activity GO:0030250 6 6 0,000 6,713E-03 0,03956115 GO:0010853|cyclase activator activity, ! negative regulation of carbohydrate metabolic process GO:0045912 8 6 0,000 6,713E-03 0,03949734 GO:0010677|negative regulation of cellular carbohydrate metabolic process, ! positive regulation of exocytosis GO:0045921 6 6 0,000 6,713E-03 0,03943374 ! protein tyrosine kinase activator activity GO:0030296 8 6 0,000 6,713E-03 0,03937034 ! protein import into mitochondrial inner membrane GO:0045039 7 6 0,000 6,713E-03 0,03930714 GO:0042719|mitochondrial intermembrane space protein transporter complex, ! positive regulation of steroid metabolic process GO:0045940 6 6 0,000 6,713E-03 0,03924415 ! LIM domain binding GO:0030274 7 6 0,000 6,713E-03 0,03918136 ! negative regulation of translational initiation GO:0045947 6 6 0,000 6,713E-03 0,03911877 ! positive regulation vascular endothelial growth factor production GO:0010575 6 6 0,000 6,713E-03 0,03905638 ! 5S class rRNA transcription GO:0042791 6 6 0,000 6,713E-03 0,03899419 GO:0042797|tRNA transcription from RNA polymerase III promoter, GO:0000127|transcription factor TFIIIC complex, ! integral to mitochondrial outer membrane GO:0031307 6 6 0,000 6,713E-03 0,03893219 ! axon guidance receptor activity GO:0008046 6 6 0,000 6,713E-03 0,0388704 ! zinc ion homeostasis GO:0055069 7 6 0,000 6,713E-03 0,03880879 ! positive regulation of gliogenesis GO:0014015 7 6 0,000 6,713E-03 0,03874739 GO:0045687|positive regulation of glial cell differentiation, ! centrosome duplication GO:0051298 7 6 0,000 6,713E-03 0,03868618 ! protein targeting to lysosome GO:0006622 6 6 0,000 6,713E-03 0,03862516 ! hyaluronan metabolic process GO:0030212 8 6 0,000 6,713E-03 0,03856433 ! protein retention in ER lumen GO:0006621 6 6 0,000 6,713E-03 0,03850369 ! ventricular cardiac muscle cell differentiation GO:0055012 8 6 0,000 6,713E-03 0,03844325 ! circadian sleep/wake cycle GO:0042745 7 6 0,000 6,713E-03 0,03838299 ! dynein binding GO:0045502 6 6 0,000 6,713E-03 0,03832293 ! regulation of dendrite development GO:0050773 6 6 0,000 6,713E-03 0,03826305 ! peptidyl-arginine modification GO:0018195 6 6 0,000 6,713E-03 0,03820335 ! eating behavior GO:0042755 7 6 0,000 6,713E-03 0,03814385 ! protein localization to chromosome GO:0034502 8 6 0,000 6,713E-03 0,03808452 ! Hsp90 protein binding GO:0051879 7 6 0,000 6,713E-03 0,03802539 ! glycolipid binding GO:0051861 7 6 0,000 6,713E-03 0,03796643 ! MutLalpha complex binding GO:0032405 8 6 0,000 6,713E-03 0,03790766 ! mast cell activation GO:0045576 6 6 0,000 6,713E-03 0,03784907 ! regulation of focal adhesion formation GO:0051893 6 6 0,000 6,713E-03 0,03779066 ! nucleoside catabolic process GO:0009164 7 6 0,000 6,713E-03 0,03773243 ! phosphatidylinositol biosynthetic process GO:0006661 6 6 0,000 6,713E-03 0,03767438 ! molybdopterin cofactor biosynthetic process GO:0032324 15 6 0,000 6,713E-03 0,03761651 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! negative regulation of multicellular organism growth GO:0040015 6 6 0,000 6,713E-03 0,03755882 ! RNA polymerase II transcription elongation factor activity GO:0016944 6 6 0,000 6,713E-03 0,0375013 ! lipoxygenase activity GO:0016165 6 6 0,000 6,713E-03 0,03744396 ! regulation of myeloid leukocyte mediated immunity GO:0002886 6 6 0,000 6,713E-03 0,03738679 ! alpha DNA polymerase:primase complex GO:0005658 16 6 0,000 6,713E-03 0,0373298 ! DNA-directed RNA polymerase III complex GO:0005666 6 6 0,000 6,713E-03 0,03727298 ! DNA replication factor C complex GO:0005663 7 6 0,000 6,713E-03 0,03721634 ! DNA replication factor A complex GO:0005662 7 6 0,000 6,713E-03 0,03715986 ! establishment of chromosome localization GO:0051303 15 6 0,000 6,713E-03 0,03710356 GO:0050000|chromosome localization, ! cilium morphogenesis GO:0060271 6 6 0,000 6,713E-03 0,03704743 ! nucleolar ribonuclease P complex GO:0005655 6 6 0,000 6,713E-03 0,03699146 GO:0030677|ribonuclease P complex, GO:0030681|multimeric ribonuclease P complex, ! intracellular lipid transport GO:0032365 6 6 0,000 6,713E-03 0,03693567 ! chromatin assembly complex GO:0005678 16 6 0,000 6,713E-03 0,03688004 ! sex chromatin GO:0001739 6 6 0,000 6,713E-03 0,03682459 GO:0000803|sex chromosome, ! morphogenesis of a polarized epithelium GO:0001738 7 6 0,000 6,713E-03 0,03676929 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 7 6 0,000 6,713E-03 0,03671417 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 6 6 0,000 6,713E-03 0,03665921 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 7 6 0,000 6,713E-03 0,03660441 ! positive regulation of pseudopodium assembly GO:0031274 6 6 0,000 6,713E-03 0,03654978 GO:0031272|regulation of pseudopodium assembly, ! regulation of lipoprotein metabolic process GO:0050746 7 6 0,000 6,713E-03 0,0364953 ! phosphatidylserine binding GO:0001786 6 6 0,000 6,713E-03 0,036441 ! alpha-mannosidase activity GO:0004559 8 6 0,000 6,713E-03 0,03638685 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 6 0,000 6,713E-03 0,03633286 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 6,713E-03 0,03627904 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 11 6 0,000 6,713E-03 0,03622537 GO:0002820|negative regulation of adaptive immune response, ! myeloid dendritic cell activation GO:0001773 8 6 0,000 6,713E-03 0,03617186 GO:0043011|myeloid dendritic cell differentiation, ! immunological synapse GO:0001772 6 6 0,000 6,713E-03 0,03611851 ! leading edge membrane GO:0031256 8 6 0,000 6,713E-03 0,03606532 ! photoreceptor connecting cilium GO:0032391 7 6 0,000 6,713E-03 0,03601228 ! CARD domain binding GO:0050700 6 6 0,000 6,713E-03 0,0359594 ! regulation of muscle cell apoptosis GO:0010660 7 6 0,000 6,713E-03 0,03590667 ! COPII vesicle coat GO:0030127 7 6 0,000 6,713E-03 0,0358541 GO:0012507|ER to Golgi transport vesicle membrane, ! molybdenum ion binding GO:0030151 15 6 0,000 6,713E-03 0,03580168 ! glutathione biosynthetic process GO:0006750 7 6 0,000 6,713E-03 0,03574942 ! positive regulation of erythrocyte differentiation GO:0045648 8 6 0,000 6,713E-03 0,0356973 ! positive regulation of epidermis development GO:0045684 8 6 0,000 6,713E-03 0,03564534 ! proteasome regulator activity GO:0010860 6 6 0,000 6,713E-03 0,03559353 ! ceramidase activity GO:0017040 6 6 0,000 6,713E-03 0,03554187 ! antibiotic transport GO:0042891 7 6 0,000 6,713E-03 0,03549036 ! tetrahydrobiopterin biosynthetic process GO:0006729 7 6 0,000 6,713E-03 0,035439 ! regulation of T-helper cell differentiation GO:0045622 6 6 0,000 6,713E-03 0,03538779 ! sodium channel regulator activity GO:0017080 6 6 0,000 6,713E-03 0,03533672 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 6,713E-03 0,03528581 ! response to fluid shear stress GO:0034405 6 6 0,000 6,713E-03 0,03523504 ! lymph node development GO:0048535 6 6 0,000 6,713E-03 0,03518441 ! negative regulation of viral reproduction GO:0048525 7 6 0,000 6,713E-03 0,03513393 ! triglyceride catabolic process GO:0019433 15 6 0,000 6,713E-03 0,0350836 ! positive regulation of fatty acid oxidation GO:0046321 6 6 0,000 6,713E-03 0,0350334 ! ectodermal gut morphogenesis GO:0048567 7 6 0,000 6,713E-03 0,03498336 GO:0007439|ectodermal gut development, ! T cell activation during immune response GO:0002286 6 6 0,000 6,713E-03 0,03493345 ! negative regulation of lipase activity GO:0060192 6 6 0,000 6,713E-03 0,03488369 ! activation of innate immune response GO:0002218 6 6 0,000 6,713E-03 0,03483407 GO:0002758|innate immune response-activating signal transduction, ! regulation of telomere maintenance via telomerase GO:0032210 7 6 0,000 6,713E-03 0,03478459 ! sarcoglycan complex GO:0016012 8 6 0,000 6,713E-03 0,03473525 ! natural killer cell mediated immunity GO:0002228 7 6 0,000 6,713E-03 0,03468605 GO:0042267|natural killer cell mediated cytotoxicity, ! phosphatidylinositol-4,5-bisphosphate binding GO:0005546 6 6 0,000 6,713E-03 0,03463699 ! neural plate development GO:0001840 7 6 0,000 6,713E-03 0,03458806 ! regulation of synaptic transmission, GABAergic GO:0032228 15 6 0,000 6,713E-03 0,03453928 ! catecholamine transport GO:0051937 6 6 0,000 6,713E-03 0,03449063 ! ether hydrolase activity GO:0016803 7 6 0,000 6,713E-03 0,03444212 ! FACIT collagen GO:0005593 6 6 0,000 6,713E-03 0,03439375 ! lactate dehydrogenase activity GO:0004457 6 6 0,000 6,713E-03 0,03434551 ! regulation of T cell receptor signaling pathway GO:0050856 7 6 0,000 6,713E-03 0,03429741 ! collagen type IV GO:0005587 6 6 0,000 6,713E-03 0,03424944 ! negative regulation of DNA replication initiation GO:0032297 6 6 0,000 6,713E-03 0,03420161 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 7 6 0,000 6,713E-03 0,0341539 ! drug metabolic process GO:0017144 6 6 0,000 6,713E-03 0,03410634 ! extracellular matrix structural constituent conferring tensile strength GO:0030020 6 6 0,000 6,713E-03 0,0340589 ! negative regulation of synaptic transmission GO:0050805 6 6 0,000 6,713E-03 0,0340116 ! hyalurononglucosaminidase activity GO:0004415 6 6 0,000 6,713E-03 0,03396442 ! nucleoside-diphosphatase activity GO:0017110 6 6 0,000 6,713E-03 0,03391738 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 6 6 0,000 6,713E-03 0,03387047 ! regulation of microtubule polymerization GO:0031113 6 6 0,000 6,713E-03 0,03382369 ! cellular anion homeostasis GO:0030002 6 6 0,000 6,713E-03 0,03377703 GO:0055081|anion homeostasis, ! regulation of MHC class II biosynthetic process GO:0045346 6 6 0,000 6,713E-03 0,03373051 ! negative regulation of protein ubiquitination GO:0031397 7 6 0,000 6,713E-03 0,03368411 ! negative regulation of fibroblast proliferation GO:0048147 6 6 0,000 6,713E-03 0,03363784 ! behavioral response to cocaine GO:0048148 9 6 0,000 6,713E-03 0,0335917 ! translation initiation factor binding GO:0031369 6 6 0,000 6,713E-03 0,03354568 ! nucleotide-sugar transport GO:0015780 6 6 0,000 6,713E-03 0,03349979 ! sulfur amino acid transmembrane transporter activity GO:0000099 6 6 0,000 6,713E-03 0,03345403 ! virion attachment to host cell surface receptor GO:0019062 6 6 0,000 6,713E-03 0,03340839 ! quaternary ammonium group binding GO:0050997 7 6 0,000 6,713E-03 0,03336287 ! actin-dependent ATPase activity GO:0030898 7 6 0,000 6,713E-03 0,03331748 ! reproductive behavior GO:0019098 8 6 0,000 6,713E-03 0,03327221 ! response to growth hormone stimulus GO:0060416 7 6 0,000 6,713E-03 0,03322707 GO:0060396|growth hormone receptor signaling pathway, ! negative regulation of JAK-STAT cascade GO:0046426 8 6 0,000 6,713E-03 0,03318205 ! nucleotide-excision repair, DNA incision GO:0033683 6 6 0,000 6,713E-03 0,03313714 ! negative regulation of cell-cell adhesion GO:0022408 8 6 0,000 6,713E-03 0,03309236 ! positive regulation of cell-cell adhesion GO:0022409 7 6 0,000 6,713E-03 0,03304771 ! induction of positive chemotaxis GO:0050930 7 6 0,000 6,713E-03 0,03300317 ! cohesin complex GO:0008278 6 6 0,000 6,713E-03 0,03295875 ! regulation of collagen biosynthetic process GO:0032965 7 6 0,000 6,713E-03 0,03291445 ! citrate metabolic process GO:0006101 7 6 0,000 6,713E-03 0,03287027 ! myelin sheath GO:0043209 8 6 0,000 6,713E-03 0,03282621 ! phototransduction, visible light GO:0007603 6 6 0,000 6,713E-03 0,03278226 ! opsonization GO:0008228 7 6 0,000 6,713E-03 0,03273844 ! 1-phosphatidylinositol-4-phosphate 5-kinase activity GO:0016308 7 6 0,000 6,713E-03 0,03269473 ! regulation of dopamine metabolic process GO:0042053 8 6 0,000 6,713E-03 0,03265113 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 7 6 0,000 6,713E-03 0,03260766 ! regulation of potassium ion transport GO:0043266 8 6 0,000 6,713E-03 0,03256429 ! cell migration involved in gastrulation GO:0042074 7 6 0,000 6,713E-03 0,03252105 ! chemoattractant activity GO:0042056 6 6 0,000 6,713E-03 0,03247792 ! regulation of systemic arterial blood pressure by norepinephrine-epinephrine GO:0001993 8 6 0,000 6,713E-03 0,0324349 ! low-density lipoprotein particle remodeling GO:0034374 6 6 0,000 6,713E-03 0,032392 ! ornithine decarboxylase regulator activity GO:0042979 6 6 0,000 6,713E-03 0,03234921 ! leukocyte degranulation GO:0043299 6 6 0,000 6,713E-03 0,03230653 ! bile acid and bile salt transport GO:0015721 7 6 0,000 6,713E-03 0,03226397 ! regulation of cytokine-mediated signaling pathway GO:0001959 11 6 0,000 6,713E-03 0,03222151 ! mitochondrial genome maintenance GO:0000002 6 6 0,000 6,713E-03 0,03217917 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 6 0,000 6,713E-03 0,03213694 ! DNA topoisomerase activity GO:0003916 6 6 0,000 6,713E-03 0,03209482 ! protein geranylgeranyltransferase activity GO:0004661 7 6 0,000 6,713E-03 0,03205281 ! ceramide biosynthetic process GO:0046513 6 6 0,000 6,713E-03 0,03201091 ! cyclin-dependent protein kinase activating kinase holoenzyme complex GO:0019907 7 6 0,000 6,713E-03 0,03196912 ! activin receptor activity GO:0017002 7 6 0,000 6,713E-03 0,03192744 ! astrocyte differentiation GO:0048708 6 6 0,000 6,713E-03 0,03188587 ! syncytium formation GO:0006949 6 6 0,000 6,713E-03 0,03184441 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 6,713E-03 0,03180305 ! neutrophil activation GO:0042119 6 6 0,000 6,713E-03 0,0317618 ! regulation of muscle hypertrophy GO:0014743 6 6 0,000 6,713E-03 0,03172066 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! regulation of appetite GO:0032098 6 6 0,000 6,713E-03 0,03167962 ! positive regulation of activated T cell proliferation GO:0042104 7 6 0,000 6,713E-03 0,03163869 ! positive transcription elongation factor activity GO:0008159 7 6 0,000 6,713E-03 0,03159787 ! NuA4 histone acetyltransferase complex GO:0035267 8 6 0,000 6,713E-03 0,03155715 ! cellular polysaccharide catabolic process GO:0044247 17 6 0,000 6,713E-03 0,03151654 GO:0009251|glucan catabolic process, ! response to salt stress GO:0009651 7 6 0,000 6,713E-03 0,03147603 ! neuron apoptosis GO:0051402 7 6 0,000 6,713E-03 0,03143562 ! folic acid transport GO:0015884 8 6 0,000 6,713E-03 0,03139532 ! carnitine transport GO:0015879 6 6 0,000 6,713E-03 0,03135512 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 6 6 0,000 6,713E-03 0,03131502 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, ! parturition GO:0007567 7 6 0,000 6,713E-03 0,03127503 ! S-methyltransferase activity GO:0008172 6 6 0,000 6,713E-03 0,03123514 ! phospholipase D activity GO:0004630 6 6 0,000 6,713E-03 0,03119535 ! poly-pyrimidine tract binding GO:0008187 6 6 0,000 6,713E-03 0,03115566 ! intercalated disc GO:0014704 8 6 0,000 6,713E-03 0,03111607 ! G2/M transition checkpoint GO:0031576 24 6 0,000 6,713E-03 0,03107659 GO:0031572|G2/M transition DNA damage checkpoint, ! interaction with symbiont GO:0051702 6 6 0,000 6,713E-03 0,0310372 ! IgG binding GO:0019864 6 6 0,000 6,713E-03 0,03099791 ! regulation of T cell cytokine production GO:0002724 6 6 0,000 6,713E-03 0,03095872 ! 3-hydroxyacyl-CoA dehydrogenase activity GO:0003857 6 6 0,000 6,713E-03 0,03091963 ! benzodiazepine receptor activity GO:0008503 7 6 0,000 6,713E-03 0,03088064 ! antigen processing and presentation of exogenous antigen GO:0019884 7 6 0,000 6,713E-03 0,03084175 ! regulation of T cell differentiation in the thymus GO:0033081 7 6 0,000 6,713E-03 0,03080296 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 6 6 0,000 6,713E-03 0,03076426 ! regulation of interleukin-4 production GO:0032673 6 6 0,000 6,713E-03 0,03072566 ! dendrite morphogenesis GO:0048813 7 6 0,000 6,713E-03 0,03068715 ! regulation of interleukin-1 production GO:0032652 7 6 0,000 6,713E-03 0,03064875 ! ribosomal large subunit biogenesis GO:0042273 7 6 0,000 6,713E-03 0,03061044 ! regulation of myeloid cell apoptosis GO:0033032 8 6 0,000 6,713E-03 0,03057222 ! nucleosome disassembly GO:0006337 7 6 0,000 6,713E-03 0,0305341 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! general transcriptional repressor activity GO:0016565 7 6 0,000 6,713E-03 0,03049608 ! regulation of mast cell activation GO:0033003 6 6 0,000 6,713E-03 0,03045815 ! tetracycline transporter activity GO:0008493 7 6 0,000 6,713E-03 0,03042031 GO:0042895|antibiotic transporter activity, ! guanylyltransferase activity GO:0070568 7 6 0,000 6,713E-03 0,03038257 ! receptor internalization GO:0031623 8 6 0,000 6,713E-03 0,03034492 ! N-formyl peptide receptor activity GO:0004982 6 6 0,000 6,713E-03 0,03030736 ! coenzyme A biosynthetic process GO:0015937 6 6 0,000 6,713E-03 0,0302699 ! histamine receptor activity GO:0004969 7 6 0,000 6,713E-03 0,03023253 ! N-methyl-D-aspartate selective glutamate receptor activity GO:0004972 9 6 0,000 6,713E-03 0,03019525 ! pyrimidine nucleotide sugar transmembrane transporter activity GO:0015165 6 6 0,000 6,713E-03 0,03015807 ! protein deubiquitination GO:0016579 6 6 0,000 6,713E-03 0,03012097 ! axonal fasciculation GO:0007413 7 6 0,000 6,713E-03 0,03008397 ! basic amino acid transmembrane transporter activity GO:0015174 6 6 0,000 6,713E-03 0,03004705 ! cytidine deaminase activity GO:0004126 6 6 0,000 6,713E-03 0,03001023 ! lipopolysaccharide-mediated signaling pathway GO:0031663 6 6 0,000 6,713E-03 0,0299735 ! energy coupled proton transport, against electrochemical gradient GO:0015988 7 6 0,000 6,713E-03 0,02993686 GO:0015991|ATP hydrolysis coupled proton transport, ! alpha-adrenergic receptor activity GO:0004936 9 6 0,000 6,713E-03 0,0299003 ! cytochrome-b5 reductase activity GO:0004128 7 6 0,000 6,713E-03 0,02986384 ! glycine binding GO:0016594 9 6 0,000 6,713E-03 0,02982747 ! apical protein localization GO:0045176 7 6 0,000 6,713E-03 0,02979118 ! ankyrin binding GO:0030506 6 6 0,000 6,713E-03 0,02975498 ! proton-transporting ATP synthase complex, catalytic core F(1) GO:0045261 6 6 0,000 6,713E-03 0,02971887 ! thyroid hormone receptor activity GO:0004887 7 6 0,000 6,713E-03 0,02968285 ! tyrosine phosphorylation of STAT protein GO:0007260 7 6 0,000 6,713E-03 0,02964691 ! progesterone metabolic process GO:0042448 6 6 0,000 6,713E-03 0,02961106 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 7 6 0,000 6,713E-03 0,0295753 ! GDP-dissociation inhibitor activity GO:0005092 6 6 0,000 6,713E-03 0,02953963 ! type II transforming growth factor beta receptor binding GO:0005114 6 6 0,000 6,713E-03 0,02950404 ! ATP catabolic process GO:0006200 6 6 0,000 6,713E-03 0,02946853 ! CoA carboxylase activity GO:0016421 6 6 0,000 6,713E-03 0,02943311 ! determination of adult lifespan GO:0008340 6 6 0,000 6,713E-03 0,02939778 ! S-acyltransferase activity GO:0016417 6 6 0,000 6,713E-03 0,02936253 ! somatic stem cell maintenance GO:0035019 6 6 0,000 6,713E-03 0,02932736 ! carnitine O-acyltransferase activity GO:0016406 6 6 0,000 6,713E-03 0,02929228 ! IkappaB kinase complex GO:0008385 7 6 0,000 6,713E-03 0,02925729 ! nucleobase transmembrane transporter activity GO:0015205 7 6 0,000 6,713E-03 0,02922237 ! store-operated calcium channel activity GO:0015279 6 6 0,000 6,713E-03 0,02918754 ! alkaline phosphatase activity GO:0004035 7 6 0,000 6,713E-03 0,0291528 ! aldehyde dehydrogenase [NAD(P)+] activity GO:0004030 6 6 0,000 6,713E-03 0,02911813 ! unconventional myosin complex GO:0016461 8 6 0,000 6,713E-03 0,02908355 ! tRNA transcription GO:0009304 7 7 0,000 7,827E-03 0,03387247 ! respiratory burst GO:0045730 7 7 0,000 7,827E-03 0,03383233 ! telencephalon cell migration GO:0022029 8 7 0,000 7,827E-03 0,0337923 ! cytokinesis during cell cycle GO:0033205 7 7 0,000 7,827E-03 0,03375235 ! cation:chloride symporter activity GO:0015377 8 7 0,000 7,827E-03 0,0337125 ! RNA cap binding GO:0000339 8 7 0,000 7,827E-03 0,03367275 ! generation of neurons in the forebrain GO:0021872 8 7 0,000 7,827E-03 0,03363309 ! ephrin receptor binding GO:0046875 9 7 0,000 7,827E-03 0,03359352 ! male meiosis I GO:0007141 7 7 0,000 7,827E-03 0,03355404 ! synapsis GO:0007129 7 7 0,000 7,827E-03 0,03351466 GO:0070192|chromosome organization involved in meiosis, ! N-terminal protein amino acid acetylation GO:0006474 8 7 0,000 7,827E-03 0,03347537 ! type I transforming growth factor beta receptor binding GO:0034713 8 7 0,000 7,827E-03 0,03343617 ! signal peptide processing GO:0006465 7 7 0,000 7,827E-03 0,03339706 ! regulation of cardiac muscle cell proliferation GO:0060043 8 7 0,000 7,827E-03 0,03335805 ! alpha(1,3)-fucosyltransferase activity GO:0046920 8 7 0,000 7,827E-03 0,03331912 ! macrophage chemotaxis GO:0048246 7 7 0,000 7,827E-03 0,03328029 ! Golgi cisterna membrane GO:0032580 7 7 0,000 7,827E-03 0,03324155 ! neurofilament cytoskeleton GO:0060053 8 7 0,000 7,827E-03 0,03320289 ! positive regulation of receptor-mediated endocytosis GO:0048260 7 7 0,000 7,827E-03 0,03316433 ! smoothened signaling pathway GO:0007224 8 7 0,000 7,827E-03 0,03312586 ! oxidoreductase activity, acting on CH or CH2 groups GO:0016725 7 7 0,000 7,827E-03 0,03308747 ! oxidoreductase activity, oxidizing metal ions GO:0016722 7 7 0,000 7,827E-03 0,03304918 ! cytoplasmic microtubule GO:0005881 7 7 0,000 7,827E-03 0,03301097 ! Arp2/3 protein complex GO:0005885 8 7 0,000 7,827E-03 0,03297285 ! fructose-2,6-bisphosphate 2-phosphatase activity GO:0004331 7 7 0,000 7,827E-03 0,03293482 ! ATPase binding GO:0051117 8 7 0,000 7,827E-03 0,03289688 ! positive regulation of isotype switching GO:0045830 7 7 0,000 7,827E-03 0,03285902 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 7,827E-03 0,03282125 ! positive regulation of gene expression, epigenetic GO:0045815 7 7 0,000 7,827E-03 0,03278357 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 7 0,000 7,827E-03 0,03274597 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 7,827E-03 0,03270846 ! thymic T cell selection GO:0045061 16 7 0,000 7,827E-03 0,03267104 ! transepithelial chloride transport GO:0030321 7 7 0,000 7,827E-03 0,0326337 GO:0070633|transepithelial transport, ! adrenal gland development GO:0030325 7 7 0,000 7,827E-03 0,03259645 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 7 7 0,000 7,827E-03 0,03255928 ! melanocyte differentiation GO:0030318 8 7 0,000 7,827E-03 0,0325222 ! malate dehydrogenase activity GO:0016615 8 7 0,000 7,827E-03 0,0324852 ! mitochondrial respiratory chain complex assembly GO:0033108 7 7 0,000 7,827E-03 0,03244828 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! DNA secondary structure binding GO:0000217 16 7 0,000 7,827E-03 0,03241145 ! oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor GO:0016653 8 7 0,000 7,827E-03 0,0323747 ! regulation of peptidyl-serine phosphorylation GO:0033135 7 7 0,000 7,827E-03 0,03233804 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 8 7 0,000 7,827E-03 0,03230146 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of granule cell precursor proliferation GO:0021936 7 7 0,000 7,827E-03 0,03226496 GO:0021940|positive regulation of granule cell precursor proliferation, ! V(D)J recombination GO:0033151 8 7 0,000 7,827E-03 0,03222854 ! tetrahydrobiopterin metabolic process GO:0046146 8 7 0,000 7,827E-03 0,03219221 ! vascular endothelial growth factor receptor activity GO:0005021 12 7 0,000 7,827E-03 0,03215596 ! central nervous system neuron axonogenesis GO:0021955 8 7 0,000 7,827E-03 0,03211979 GO:0021952|central nervous system projection neuron axonogenesis, ! oxidoreductase activity, acting on diphenols and related substances as donors GO:0016679 7 7 0,000 7,827E-03 0,0320837 GO:0016681|oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor, GO:0008121|ubiquinol-cytochrome-c reductase activity, ! response to tumor necrosis factor GO:0034612 8 7 0,000 7,827E-03 0,03204769 ! peptidoglycan metabolic process GO:0000270 9 7 0,000 7,827E-03 0,03201176 GO:0009253|peptidoglycan catabolic process, ! response to ATP GO:0033198 7 7 0,000 7,827E-03 0,03197591 ! signal recognition particle, endoplasmic reticulum targeting GO:0005786 8 7 0,000 7,827E-03 0,03194014 GO:0048500|signal recognition particle, ! stereocilium GO:0032420 10 7 0,000 7,827E-03 0,03190446 ! paraxial mesoderm morphogenesis GO:0048340 9 7 0,000 7,827E-03 0,03186885 ! melanosome organization GO:0032438 7 7 0,000 7,827E-03 0,03183332 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 8 7 0,000 7,827E-03 0,03179787 ! mesodermal cell differentiation GO:0048333 9 7 0,000 7,827E-03 0,0317625 GO:0001710|mesodermal cell fate commitment, ! positive regulation of neuroblast proliferation GO:0002052 7 7 0,000 7,827E-03 0,03172721 ! Rac protein signal transduction GO:0016601 7 7 0,000 7,827E-03 0,031692 ! chondrocyte differentiation GO:0002062 7 7 0,000 7,827E-03 0,03165686 ! guanylate cyclase regulator activity GO:0030249 7 7 0,000 7,827E-03 0,0316218 GO:0010851|cyclase regulator activity, ! intestinal cholesterol absorption GO:0030299 9 7 0,000 7,827E-03 0,03158682 ! negative regulation of specific transcription from RNA polymerase II promoter GO:0010553 8 7 0,000 7,827E-03 0,03155192 ! positive regulation of mitotic cell cycle GO:0045931 7 7 0,000 7,827E-03 0,0315171 ! determination of anterior/posterior axis, embryo GO:0008595 10 7 0,000 7,827E-03 0,03148235 GO:0007350|blastoderm segmentation, GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 8 7 0,000 7,827E-03 0,03144768 ! regulation of vascular endothelial growth factor production GO:0010574 7 7 0,000 7,827E-03 0,03141308 ! Schwann cell differentiation GO:0014037 8 7 0,000 7,827E-03 0,03137856 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 9 7 0,000 7,827E-03 0,03134412 ! lipopolysaccharide biosynthetic process GO:0009103 7 7 0,000 7,827E-03 0,03130975 ! CDP-alcohol phosphatidyltransferase activity GO:0017169 7 7 0,000 7,827E-03 0,03127545 ! vinculin binding GO:0017166 9 7 0,000 7,827E-03 0,03124124 ! intrinsic to mitochondrial outer membrane GO:0031306 7 7 0,000 7,827E-03 0,03120709 ! regulation of collagen metabolic process GO:0010712 8 7 0,000 7,827E-03 0,03117302 ! wound healing, spreading of epidermal cells GO:0035313 7 7 0,000 7,827E-03 0,03113903 ! negative regulation of gliogenesis GO:0014014 8 7 0,000 7,827E-03 0,03110511 GO:0045686|negative regulation of glial cell differentiation, ! translation termination factor activity GO:0008079 7 7 0,000 7,827E-03 0,03107126 GO:0003747|translation release factor activity, ! purine base biosynthetic process GO:0009113 8 7 0,000 7,827E-03 0,03103749 ! cardiac muscle cell development GO:0055013 8 7 0,000 7,827E-03 0,03100379 ! fibrinolysis GO:0042730 9 7 0,000 7,827E-03 0,03097016 ! response to tropane GO:0014073 10 7 0,000 7,827E-03 0,03093661 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 7 7 0,000 7,827E-03 0,03090313 GO:0051904|pigment granule transport, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 8 7 0,000 7,827E-03 0,03086972 ! glycosylceramide metabolic process GO:0006677 7 7 0,000 7,827E-03 0,03083638 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 7 7 0,000 7,827E-03 0,03080312 ! laminin-1 complex GO:0005606 7 7 0,000 7,827E-03 0,03076992 GO:0043256|laminin complex, ! regulation of chondrocyte differentiation GO:0032330 8 7 0,000 7,827E-03 0,0307368 ! positive regulation of immunoglobulin mediated immune response GO:0002891 7 7 0,000 7,827E-03 0,03070375 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of lipid transport GO:0032370 8 7 0,000 7,827E-03 0,03067077 ! regulation of cell division GO:0051302 7 7 0,000 7,827E-03 0,03063786 ! holo TFIIH complex GO:0005675 7 7 0,000 7,827E-03 0,03060503 ! mannosyl-oligosaccharide 1,2-alpha-mannosidase activity GO:0004571 10 7 0,000 7,827E-03 0,03057226 ! chitinase activity GO:0004568 7 7 0,000 7,827E-03 0,03053956 GO:0006046|N-acetylglucosamine catabolic process, GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! regulation of immune response to tumor cell GO:0002837 8 7 0,000 7,827E-03 0,03050693 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! U12-type spliceosomal complex GO:0005689 8 7 0,000 7,827E-03 0,03047438 ! regulation of respiratory burst GO:0060263 8 7 0,000 7,827E-03 0,03044189 ! prophase GO:0051324 8 7 0,000 7,827E-03 0,03040947 ! peptidyl-histidine modification GO:0018202 8 7 0,000 7,827E-03 0,03037712 ! centriolar satellite GO:0034451 10 7 0,000 7,827E-03 0,03034483 ! BBSome GO:0034464 7 7 0,000 7,827E-03 0,03031262 ! glycerophosphodiester phosphodiesterase activity GO:0008889 7 7 0,000 7,827E-03 0,03028048 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 7,827E-03 0,0302484 ! negative regulation of lymphocyte differentiation GO:0045620 8 7 0,000 7,827E-03 0,03021639 ! negative regulation of transmission of nerve impulse GO:0051970 7 7 0,000 7,827E-03 0,03018445 ! regulation of synaptic transmission, glutamatergic GO:0051966 8 7 0,000 7,827E-03 0,03015258 ! regulation of synaptogenesis GO:0051963 7 7 0,000 7,827E-03 0,03012077 ! serine family amino acid catabolic process GO:0009071 7 7 0,000 7,827E-03 0,03008903 ! MHC class I peptide loading complex GO:0042824 7 7 0,000 7,827E-03 0,03005736 ! glycolipid catabolic process GO:0019377 7 7 0,000 7,827E-03 0,03002575 GO:0046479|glycosphingolipid catabolic process, ! racemase and epimerase activity, acting on carbohydrates and derivatives GO:0016857 8 7 0,000 7,827E-03 0,02999421 ! circadian behavior GO:0048512 9 7 0,000 7,827E-03 0,02996274 ! dorsal/ventral axis specification GO:0009950 7 7 0,000 7,827E-03 0,02993133 ! ligase activity, forming carbon-carbon bonds GO:0016885 9 7 0,000 7,827E-03 0,02989999 ! striatum development GO:0021756 7 7 0,000 7,827E-03 0,02986871 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides GO:0016812 8 7 0,000 7,827E-03 0,0298375 ! triglyceride biosynthetic process GO:0019432 7 7 0,000 7,827E-03 0,02980636 ! cerebellar Purkinje cell layer development GO:0021680 7 7 0,000 7,827E-03 0,02977528 ! carbon-nitrogen lyase activity GO:0016840 7 7 0,000 7,827E-03 0,02974426 ! dystroglycan complex GO:0016011 9 7 0,000 7,827E-03 0,02971331 ! negative regulation of calcium ion transport GO:0051926 7 7 0,000 7,827E-03 0,02968242 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 8 7 0,000 7,827E-03 0,0296516 ! peroxiredoxin activity GO:0051920 7 7 0,000 7,827E-03 0,02962084 ! muscle adaptation GO:0043500 7 7 0,000 7,827E-03 0,02959014 ! regulation of muscle adaptation GO:0043502 7 7 0,000 7,827E-03 0,02955951 ! diacylglycerol metabolic process GO:0046339 7 7 0,000 7,827E-03 0,02952894 ! lysogeny GO:0030069 7 7 0,000 7,827E-03 0,02949844 GO:0019047|provirus integration, ! protein insertion into membrane GO:0051205 7 7 0,000 7,827E-03 0,029468 ! sequestering of metal ion GO:0051238 9 7 0,000 7,827E-03 0,02943762 ! membrane attack complex GO:0005579 7 7 0,000 7,827E-03 0,0294073 ! fibrinogen complex GO:0005577 7 7 0,000 7,827E-03 0,02937705 ! metallo-sulfur cluster assembly GO:0031163 9 7 0,000 7,827E-03 0,02934685 GO:0016226|iron-sulfur cluster assembly, ! extracellular matrix structural constituent conferring compression resistance GO:0030021 8 7 0,000 7,827E-03 0,02931672 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 8 7 0,000 7,827E-03 0,02928666 ! GABA receptor binding GO:0050811 8 7 0,000 7,827E-03 0,02925665 ! sheet-forming collagen GO:0030935 7 7 0,000 7,827E-03 0,0292267 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 8 7 0,000 7,827E-03 0,02919682 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 8 7 0,000 7,827E-03 0,029167 ! sphingomyelin phosphodiesterase activity GO:0004767 9 7 0,000 7,827E-03 0,02913723 ! regulation of epithelial cell differentiation GO:0030856 7 7 0,000 7,827E-03 0,02910753 ! 7S RNA binding GO:0008312 8 7 0,000 7,827E-03 0,02907789 ! positive regulation of lipid catabolic process GO:0050996 7 7 0,000 7,827E-03 0,02904831 ! protein phosphorylated amino acid binding GO:0045309 9 7 0,000 7,827E-03 0,02901879 ! 3',5'-cyclic-GMP phosphodiesterase activity GO:0047555 8 7 0,000 7,827E-03 0,02898933 ! regulation of long-term neuronal synaptic plasticity GO:0048169 17 7 0,000 7,827E-03 0,02895993 ! Golgi to endosome transport GO:0006895 8 7 0,000 7,827E-03 0,02893059 ! glucocorticoid receptor signaling pathway GO:0042921 7 7 0,000 7,827E-03 0,02890131 GO:0031958|corticosteroid receptor signaling pathway, ! succinate metabolic process GO:0006105 7 7 0,000 7,827E-03 0,02887208 ! fibril GO:0043205 7 7 0,000 7,827E-03 0,02884292 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 7,827E-03 0,02881381 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 7,827E-03 0,02878477 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 7 0,000 7,827E-03 0,02875578 ! sensory perception of bitter taste GO:0050913 7 7 0,000 7,827E-03 0,02872685 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 7,827E-03 0,02869798 ! posttranscriptional gene silencing by RNA GO:0035194 9 7 0,000 7,827E-03 0,02866917 GO:0016441|posttranscriptional gene silencing, ! cell division site part GO:0032155 9 7 0,000 7,827E-03 0,02864041 GO:0032153|cell division site, ! laminin binding GO:0043236 7 7 0,000 7,827E-03 0,02861171 ! equilibrioception GO:0050957 10 7 0,000 7,827E-03 0,02858307 ! G-protein coupled receptor kinase activity GO:0004703 9 7 0,000 7,827E-03 0,02855449 ! titin binding GO:0031432 7 7 0,000 7,827E-03 0,02852596 ! chemosensory behavior GO:0007635 9 7 0,000 7,827E-03 0,02849749 ! regulation of response to extracellular stimulus GO:0032104 7 7 0,000 7,827E-03 0,02846908 GO:0032107|regulation of response to nutrient levels, ! plasma lipoprotein particle assembly GO:0034377 7 7 0,000 7,827E-03 0,02844073 ! cobalamin binding GO:0031419 7 7 0,000 7,827E-03 0,02841243 ! sodium:phosphate symporter activity GO:0005436 8 7 0,000 7,827E-03 0,02838418 ! response to axon injury GO:0048678 9 7 0,000 7,827E-03 0,028356 ! regulation of activin receptor signaling pathway GO:0032925 7 7 0,000 7,827E-03 0,02832787 ! non-membrane spanning protein tyrosine phosphatase activity GO:0004726 8 7 0,000 7,827E-03 0,02829979 ! F-actin capping protein complex GO:0008290 8 7 0,000 7,827E-03 0,02827177 ! sphingoid biosynthetic process GO:0046520 7 7 0,000 7,827E-03 0,02824381 ! cGMP-mediated signaling GO:0019934 8 7 0,000 7,827E-03 0,0282159 ! nerve growth factor receptor signaling pathway GO:0048011 8 7 0,000 7,827E-03 0,02818804 ! cAMP-dependent protein kinase activity GO:0004691 7 7 0,000 7,827E-03 0,02816025 ! senescence GO:0010149 8 7 0,000 7,827E-03 0,0281325 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 10 7 0,000 7,827E-03 0,02810481 ! nuclear localization sequence binding GO:0008139 8 7 0,000 7,827E-03 0,02807718 ! galactose metabolic process GO:0006012 8 7 0,000 7,827E-03 0,0280496 ! vesicle fusion GO:0006906 8 7 0,000 7,827E-03 0,02802207 ! maintenance of protein location in nucleus GO:0051457 7 7 0,000 7,827E-03 0,0279946 ! intracellular pH reduction GO:0051452 7 7 0,000 7,827E-03 0,02796718 ! glycerol ether catabolic process GO:0044269 16 7 0,000 7,827E-03 0,02793981 GO:0046461|neutral lipid catabolic process, GO:0046464|acylglycerol catabolic process, ! neurotransmitter catabolic process GO:0042135 9 7 0,000 7,827E-03 0,0279125 ! ruffle organization GO:0031529 9 7 0,000 7,827E-03 0,02788524 ! nucleoside transport GO:0015858 8 7 0,000 7,827E-03 0,02785804 ! attachment of GPI anchor to protein GO:0016255 8 7 0,000 7,827E-03 0,02783089 ! inclusion body GO:0016234 7 7 0,000 7,827E-03 0,02780379 ! Cajal body GO:0015030 7 7 0,000 7,827E-03 0,02777674 ! H4/H2A histone acetyltransferase complex GO:0043189 9 7 0,000 7,827E-03 0,02774975 ! rRNA modification GO:0000154 7 7 0,000 7,827E-03 0,02772281 ! PcG protein complex GO:0031519 7 7 0,000 7,827E-03 0,02769592 ! phosphatidate phosphatase activity GO:0008195 7 7 0,000 7,827E-03 0,02766908 ! NAD-dependent protein deacetylase activity GO:0034979 7 7 0,000 7,827E-03 0,02764229 GO:0017136|NAD-dependent histone deacetylase activity, ! spindle checkpoint GO:0031577 7 7 0,000 7,827E-03 0,02761556 ! apolipoprotein binding GO:0034185 9 7 0,000 7,827E-03 0,02758888 ! G1 DNA damage checkpoint GO:0031571 7 7 0,000 7,827E-03 0,02756225 ! segment specification GO:0007379 9 7 0,000 7,827E-03 0,02753567 ! pronucleus GO:0045120 25 7 0,000 7,827E-03 0,02750914 ! bile acid:sodium symporter activity GO:0008508 9 7 0,000 7,827E-03 0,02748267 ! Rac GTPase activator activity GO:0030675 9 7 0,000 7,827E-03 0,02745624 ! regulation of DNA repair GO:0006282 19 7 0,000 7,827E-03 0,02742987 ! preribosome GO:0030684 7 7 0,000 7,827E-03 0,02740354 ! DNA topological change GO:0006265 7 7 0,000 7,827E-03 0,02737727 ! DNA ligation GO:0006266 8 7 0,000 7,827E-03 0,02735104 ! hair follicle maturation GO:0048820 8 7 0,000 7,827E-03 0,02732487 ! renal water homeostasis GO:0003091 7 7 0,000 7,827E-03 0,02729875 ! clathrin-coated endocytic vesicle membrane GO:0030669 7 7 0,000 7,827E-03 0,02727267 ! positive regulation of interleukin-6 production GO:0032755 7 7 0,000 7,827E-03 0,02724665 ! interleukin-1 receptor activity GO:0004908 8 7 0,000 7,827E-03 0,02722068 ! positive regulation of tumor necrosis factor production GO:0032760 7 7 0,000 7,827E-03 0,02719475 ! positive regulation of monooxygenase activity GO:0032770 7 7 0,000 7,827E-03 0,02716888 ! inositol trisphosphate 3-kinase activity GO:0008440 8 7 0,000 7,827E-03 0,02714305 ! phosphofructokinase activity GO:0008443 7 7 0,000 7,827E-03 0,02711727 ! gap junction channel activity GO:0005243 8 7 0,000 7,827E-03 0,02709155 ! 3',5'-cyclic-AMP phosphodiesterase activity GO:0004115 10 7 0,000 7,827E-03 0,02706587 ! histone methylation GO:0016571 7 7 0,000 7,827E-03 0,02704024 ! positive regulation of interferon-gamma production GO:0032729 7 7 0,000 7,827E-03 0,02701465 ! negative regulation of tumor necrosis factor production GO:0032720 9 7 0,000 7,827E-03 0,02698912 ! muscle cell proliferation GO:0033002 8 7 0,000 7,827E-03 0,02696364 ! transcription termination GO:0006353 9 7 0,000 7,827E-03 0,0269382 ! regulation of transcription from RNA polymerase III promoter GO:0006359 16 7 0,000 7,827E-03 0,02691281 ! sodium:amino acid symporter activity GO:0005283 7 7 0,000 7,827E-03 0,02688747 ! cytidylyltransferase activity GO:0070567 8 7 0,000 7,827E-03 0,02686217 ! monolayer-surrounded lipid storage body GO:0012511 7 7 0,000 7,827E-03 0,02683693 ! ATP-dependent peptidase activity GO:0004176 7 7 0,000 7,827E-03 0,02681173 ! salivary gland development GO:0007431 7 7 0,000 7,827E-03 0,02678658 ! glucosidase activity GO:0015926 8 7 0,000 7,827E-03 0,02676147 ! NuRD complex GO:0016581 8 7 0,000 7,827E-03 0,02673641 ! negative regulation of nuclear division GO:0051784 7 7 0,000 7,827E-03 0,0267114 GO:0045839|negative regulation of mitosis, ! ATP-gated cation channel activity GO:0004931 9 7 0,000 7,827E-03 0,02668644 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 7 7 0,000 7,827E-03 0,02666152 ! response to redox state GO:0051775 8 7 0,000 7,827E-03 0,02663665 ! positive regulation of leukocyte chemotaxis GO:0002690 7 7 0,000 7,827E-03 0,02661183 GO:0002688|regulation of leukocyte chemotaxis, ! melanin biosynthetic process GO:0042438 8 7 0,000 7,827E-03 0,02658705 ! procollagen-proline dioxygenase activity GO:0019798 7 7 0,000 7,827E-03 0,02656232 ! actin monomer binding GO:0003785 7 7 0,000 7,827E-03 0,02653763 ! protein prenyltransferase activity GO:0008318 8 7 0,000 7,827E-03 0,02651299 ! endosome to lysosome transport GO:0008333 7 7 0,000 7,827E-03 0,02648839 ! regulation of Rac protein signal transduction GO:0035020 17 7 0,000 7,827E-03 0,02646385 ! germ cell migration GO:0008354 7 7 0,000 7,827E-03 0,02643934 ! fibroblast growth factor receptor binding GO:0005104 8 7 0,000 7,827E-03 0,02641488 ! negative regulation of organic acid transport GO:0032891 8 7 0,000 7,827E-03 0,02639047 ! CoA-ligase activity GO:0016405 8 7 0,000 7,827E-03 0,0263661 ! positive regulation of NF-kappaB import into nucleus GO:0042346 8 7 0,000 7,827E-03 0,02634178 ! interferon-alpha/beta receptor binding GO:0005132 7 7 0,000 7,827E-03 0,0263175 ! embryonic heart tube development GO:0035050 8 7 0,000 7,827E-03 0,02629327 ! dihydropyridine-sensitive calcium channel activity GO:0015270 10 7 0,000 7,827E-03 0,02626908 ! kainate selective glutamate receptor activity GO:0015277 8 7 0,000 7,827E-03 0,02624494 ! negative regulation of nucleotide metabolic process GO:0045980 8 7 0,000 7,827E-03 0,02622084 ! amiloride-sensitive sodium channel activity GO:0015280 7 7 0,000 7,827E-03 0,02619678 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 7,827E-03 0,02617277 ! adenylate kinase activity GO:0004017 8 7 0,000 7,827E-03 0,0261488 ! negative regulation of immune effector process GO:0002698 13 7 0,000 7,827E-03 0,02612488 ! C-X-C chemokine receptor activity GO:0016494 7 7 0,000 7,827E-03 0,026101 ! vacuolar proton-transporting V-type ATPase complex GO:0016471 7 7 0,000 7,827E-03 0,02607716 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 10 8 0,000 8,941E-03 0,02975938 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 9 8 0,000 8,941E-03 0,02973226 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 8 0,000 8,941E-03 0,02970518 ! chaperone mediated protein folding requiring cofactor GO:0051085 8 8 0,000 8,941E-03 0,02967815 ! negative regulation of lipid biosynthetic process GO:0051055 18 8 0,000 8,941E-03 0,02965117 ! regulation of cellular amine metabolic process GO:0033238 10 8 0,000 8,941E-03 0,02962424 ! proteasome regulatory particle GO:0005838 8 8 0,000 8,941E-03 0,02959735 ! SMAD protein complex assembly GO:0007183 10 8 0,000 8,941E-03 0,02957052 ! regulation of smooth muscle cell migration GO:0014910 11 8 0,000 8,941E-03 0,02954374 ! protein self-association GO:0043621 8 8 0,000 8,941E-03 0,029517 ! glycine hydroxymethyltransferase activity GO:0004372 9 8 0,000 8,941E-03 0,02949031 ! sodium:potassium-exchanging ATPase complex GO:0005890 10 8 0,000 8,941E-03 0,02946367 ! neurotransmitter uptake GO:0001504 8 8 0,000 8,941E-03 0,02943708 ! regulation of activated T cell proliferation GO:0046006 9 8 0,000 8,941E-03 0,02941054 ! guanylate cyclase activity GO:0004383 9 8 0,000 8,941E-03 0,02938404 ! troponin complex GO:0005861 8 8 0,000 8,941E-03 0,02935759 ! eukaryotic translation initiation factor 3 complex GO:0005852 8 8 0,000 8,941E-03 0,02933119 ! tachykinin receptor signaling pathway GO:0007217 8 8 0,000 8,941E-03 0,02930484 ! negative regulation of muscle cell differentiation GO:0051148 10 8 0,000 8,941E-03 0,02927853 ! microtubule bundle formation GO:0001578 8 8 0,000 8,941E-03 0,02925227 ! middle ear morphogenesis GO:0042474 10 8 0,000 8,941E-03 0,02922606 ! ganglioside metabolic process GO:0001573 8 8 0,000 8,941E-03 0,0291999 ! regulation of mesenchymal cell proliferation GO:0010464 9 8 0,000 8,941E-03 0,02917378 GO:0002053|positive regulation of mesenchymal cell proliferation, ! ovulation from ovarian follicle GO:0001542 8 8 0,000 8,941E-03 0,02914771 ! ciliary or flagellar motility GO:0001539 8 8 0,000 8,941E-03 0,02912168 ! pathogenesis GO:0009405 8 8 0,000 8,941E-03 0,0290957 ! pH reduction GO:0045851 9 8 0,000 8,941E-03 0,02906977 ! small protein activating enzyme activity GO:0008641 10 8 0,000 8,941E-03 0,02904389 ! ribonucleoside triphosphate catabolic process GO:0009203 8 8 0,000 8,941E-03 0,02901805 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 8 8 0,000 8,941E-03 0,02899225 ! hemoglobin metabolic process GO:0020027 8 8 0,000 8,941E-03 0,0289665 ! regulation of S phase of mitotic cell cycle GO:0007090 8 8 0,000 8,941E-03 0,0289408 ! arginine catabolic process GO:0006527 9 8 0,000 8,941E-03 0,02891515 ! T-tubule GO:0030315 9 8 0,000 8,941E-03 0,02888953 ! regulation of defense response to virus by virus GO:0050690 17 8 0,000 8,941E-03 0,02886397 ! histidine catabolic process GO:0006548 8 8 0,000 8,941E-03 0,02883845 GO:0009077|histidine family amino acid catabolic process, ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor GO:0016624 8 8 0,000 8,941E-03 0,02881297 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 8 0,000 8,941E-03 0,02878754 ! oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor GO:0016634 10 8 0,000 8,941E-03 0,02876216 ! proline metabolic process GO:0006560 10 8 0,000 8,941E-03 0,02873681 ! L-serine metabolic process GO:0006563 9 8 0,000 8,941E-03 0,02871152 ! oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor GO:0016668 8 8 0,000 8,941E-03 0,02868627 ! melanosome membrane GO:0033162 9 8 0,000 8,941E-03 0,02866106 GO:0045009|chitosome, ! phosphagen metabolic process GO:0006599 8 8 0,000 8,941E-03 0,02863589 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 8 8 0,000 8,941E-03 0,02861078 ! pericentriolar material GO:0000242 9 8 0,000 8,941E-03 0,0285857 ! reverse cholesterol transport GO:0043691 8 8 0,000 8,941E-03 0,02856067 ! tumor necrosis factor receptor activity GO:0005031 8 8 0,000 8,941E-03 0,02853568 ! melanin metabolic process GO:0006582 10 8 0,000 8,941E-03 0,02851074 ! proton-transporting V-type ATPase, V1 domain GO:0033180 8 8 0,000 8,941E-03 0,02848584 ! phasic smooth muscle contraction GO:0014821 9 8 0,000 8,941E-03 0,02846098 ! Golgi lumen GO:0005796 8 8 0,000 8,941E-03 0,02843617 ! positive regulation of endothelial cell migration GO:0010595 9 8 0,000 8,941E-03 0,0284114 ! regulation of Cdc42 protein signal transduction GO:0032489 9 8 0,000 8,941E-03 0,02838667 GO:0043088|regulation of Cdc42 GTPase activity, ! methyltransferase complex GO:0034708 8 8 0,000 8,941E-03 0,02836199 GO:0035097|histone methyltransferase complex, ! paraxial mesoderm development GO:0048339 10 8 0,000 8,941E-03 0,02833734 ! stereocilium bundle GO:0032421 11 8 0,000 8,941E-03 0,02831275 ! forebrain cell migration GO:0021885 9 8 0,000 8,941E-03 0,02828819 ! peptidyl-threonine phosphorylation GO:0018107 11 8 0,000 8,941E-03 0,02826368 ! osteoblast development GO:0002076 11 8 0,000 8,941E-03 0,02823921 ! retinoic acid metabolic process GO:0042573 8 8 0,000 8,941E-03 0,02821478 ! retinol metabolic process GO:0042572 8 8 0,000 8,941E-03 0,02819039 ! negative regulation of muscle contraction GO:0045932 10 8 0,000 8,941E-03 0,02816605 ! structural constituent of epidermis GO:0030280 9 8 0,000 8,941E-03 0,02814175 ! clathrin binding GO:0030276 10 8 0,000 8,941E-03 0,02811749 ! phosphatidylinositol bisphosphate phosphatase activity GO:0034593 9 8 0,000 8,941E-03 0,02809327 ! chondroitin sulfate biosynthetic process GO:0030206 9 8 0,000 8,941E-03 0,02806909 GO:0030204|chondroitin sulfate metabolic process, ! sodium:dicarboxylate symporter activity GO:0017153 9 8 0,000 8,941E-03 0,02804496 ! motor axon guidance GO:0008045 8 8 0,000 8,941E-03 0,02802086 ! protein targeting to vacuole GO:0006623 8 8 0,000 8,941E-03 0,02799681 ! negative regulation of axonogenesis GO:0050771 12 8 0,000 8,941E-03 0,0279728 ! peptidyl-asparagine modification GO:0018196 8 8 0,000 8,941E-03 0,02794883 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! melanosome localization GO:0032400 8 8 0,000 8,941E-03 0,0279249 GO:0032401|establishment of melanosome localization, GO:0051875|pigment granule localization, GO:0051905|establishment of pigment granule localization, ! mismatch repair complex binding GO:0032404 10 8 0,000 8,941E-03 0,02790101 ! nucleoside diphosphate metabolic process GO:0009132 9 8 0,000 8,941E-03 0,02787717 ! protein-lipid complex assembly GO:0065005 8 8 0,000 8,941E-03 0,02785336 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 9 8 0,000 8,941E-03 0,02782959 ! phosphoinositide 3-kinase cascade GO:0014065 8 8 0,000 8,941E-03 0,02780587 ! regulation of dopamine secretion GO:0014059 9 8 0,000 8,941E-03 0,02778218 ! regulation of protein kinase B signaling cascade GO:0051896 9 8 0,000 8,941E-03 0,02775854 ! cranial nerve morphogenesis GO:0021602 9 8 0,000 8,941E-03 0,02773494 ! subpallium development GO:0021544 8 8 0,000 8,941E-03 0,02771137 ! positive regulation of Rho GTPase activity GO:0032321 11 8 0,000 8,941E-03 0,02768785 ! icosanoid secretion GO:0032309 10 8 0,000 8,941E-03 0,02766436 GO:0050482|arachidonic acid secretion, ! negative regulation of oxidoreductase activity GO:0051354 8 8 0,000 8,941E-03 0,02764092 ! regulation of DNA replication initiation GO:0030174 8 8 0,000 8,941E-03 0,02761751 ! negative regulation of cytokine secretion GO:0050710 10 8 0,000 8,941E-03 0,02759415 ! dolichyl-diphosphooligosaccharide-protein glycotransferase activity GO:0004579 8 8 0,000 8,941E-03 0,02757082 ! exodeoxyribonuclease activity GO:0004529 18 8 0,000 8,941E-03 0,02754754 GO:0016895|exodeoxyribonuclease activity, producing 5'-phosphomonoesters, ! ER to Golgi transport vesicle GO:0030134 9 8 0,000 8,941E-03 0,02752429 ! nucleotide diphosphatase activity GO:0004551 9 8 0,000 8,941E-03 0,02750108 ! regulation of myoblast differentiation GO:0045661 9 8 0,000 8,941E-03 0,02747791 ! ubiquinone metabolic process GO:0006743 9 8 0,000 8,941E-03 0,02745478 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! neuromuscular process controlling posture GO:0050884 8 8 0,000 8,941E-03 0,02743169 ! multicellular organismal water homeostasis GO:0050891 8 8 0,000 8,941E-03 0,02740864 ! branched chain family amino acid catabolic process GO:0009083 9 8 0,000 8,941E-03 0,02738563 ! Wnt receptor activity GO:0042813 11 8 0,000 8,941E-03 0,02736265 ! intramolecular oxidoreductase activity, interconverting aldoses and ketoses GO:0016861 8 8 0,000 8,941E-03 0,02733972 ! leukocyte mediated cytotoxicity GO:0001909 10 8 0,000 8,941E-03 0,02731682 ! detection of calcium ion GO:0005513 9 8 0,000 8,941E-03 0,02729396 ! negative regulation of glucose import GO:0046325 9 8 0,000 8,941E-03 0,02727114 ! blastocyst growth GO:0001832 8 8 0,000 8,941E-03 0,02724836 ! regulation of fibrinolysis GO:0051917 8 8 0,000 8,941E-03 0,02722561 ! negative regulation of telomere maintenance GO:0032205 9 8 0,000 8,941E-03 0,02720291 ! cerebellar cortex formation GO:0021697 9 8 0,000 8,941E-03 0,02718024 ! complement binding GO:0001848 11 8 0,000 8,941E-03 0,02715761 ! regulation of actin filament bundle formation GO:0032231 13 8 0,000 8,941E-03 0,02713501 GO:0051492|regulation of stress fiber formation, ! regulation of synaptic transmission, dopaminergic GO:0032225 10 8 0,000 8,941E-03 0,02711246 ! negative regulation of blood vessel endothelial cell migration GO:0043537 9 8 0,000 8,941E-03 0,02708994 ! amino sugar catabolic process GO:0046348 8 8 0,000 8,941E-03 0,02706746 GO:0006043|glucosamine catabolic process, ! FK506 binding GO:0005528 9 8 0,000 8,941E-03 0,02704501 GO:0005527|macrolide binding, ! dipeptidase activity GO:0016805 8 8 0,000 8,941E-03 0,0270226 ! positive regulation of amine transport GO:0051954 9 8 0,000 8,941E-03 0,02700023 ! release of sequestered calcium ion into cytosol GO:0051209 13 8 0,000 8,941E-03 0,0269779 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, ! B cell receptor signaling pathway GO:0050853 13 8 0,000 8,941E-03 0,02695561 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 8,941E-03 0,02693335 ! Golgi transport complex GO:0017119 8 8 0,000 8,941E-03 0,02691113 ! positive regulation of protein ubiquitination GO:0031398 17 8 0,000 8,941E-03 0,02688894 ! GDP binding GO:0019003 9 8 0,000 8,941E-03 0,02686679 ! positive regulation of glucose metabolic process GO:0010907 8 8 0,000 8,941E-03 0,02684468 ! prostate gland development GO:0030850 17 8 0,000 8,941E-03 0,0268226 ! DNA synthesis during DNA repair GO:0000731 19 8 0,000 8,941E-03 0,02680056 ! nitric-oxide synthase binding GO:0050998 9 8 0,000 8,941E-03 0,02677856 ! phosphate transport GO:0006817 9 8 0,000 8,941E-03 0,02675659 ! cellular copper ion homeostasis GO:0006878 8 8 0,000 8,941E-03 0,02673466 ! oligopeptide transport GO:0006857 8 8 0,000 8,941E-03 0,02671276 GO:0015198|oligopeptide transporter activity, ! pigment cell differentiation GO:0050931 9 8 0,000 8,941E-03 0,0266909 ! 5'-nucleotidase activity GO:0008253 8 8 0,000 8,941E-03 0,02666908 ! oligosaccharyltransferase complex GO:0008250 8 8 0,000 8,941E-03 0,02664729 ! lipoprotein transport GO:0042953 9 8 0,000 8,941E-03 0,02662554 ! estrogen metabolic process GO:0008210 8 8 0,000 8,941E-03 0,02660382 ! nucleocytoplasmic transporter activity GO:0005487 8 8 0,000 8,941E-03 0,02658214 ! glucocorticoid metabolic process GO:0008211 8 8 0,000 8,941E-03 0,02656049 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 8 8 0,000 8,941E-03 0,02653888 ! T-helper 1 type immune response GO:0042088 8 8 0,000 8,941E-03 0,0265173 ! amyloid precursor protein catabolic process GO:0042987 10 8 0,000 8,941E-03 0,02649576 ! response to amphetamine GO:0001975 11 8 0,000 8,941E-03 0,02647426 ! mechanosensory behavior GO:0007638 8 8 0,000 8,941E-03 0,02645278 ! detection of chemical stimulus involved in sensory perception GO:0050907 8 8 0,000 8,941E-03 0,02643135 ! DNA-(apurinic or apyrimidinic site) lyase activity GO:0003906 8 8 0,000 8,941E-03 0,02640995 ! C-X-C chemokine binding GO:0019958 8 8 0,000 8,941E-03 0,02638858 ! two-component signal transduction system (phosphorelay) GO:0000160 9 8 0,000 8,941E-03 0,02636725 ! glycerolipid catabolic process GO:0046503 17 8 0,000 8,941E-03 0,02634595 ! spinal cord dorsal/ventral patterning GO:0021513 10 8 0,000 8,941E-03 0,02632468 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 9 8 0,000 8,941E-03 0,02630345 ! inositol phosphate-mediated signaling GO:0048016 9 8 0,000 8,941E-03 0,02628226 ! insulin-like growth factor receptor signaling pathway GO:0048009 8 8 0,000 8,941E-03 0,0262611 ! pigment granule organization GO:0048753 9 8 0,000 8,941E-03 0,02623997 ! GTP-dependent protein binding GO:0030742 11 8 0,000 8,941E-03 0,02621888 ! myeloid leukocyte mediated immunity GO:0002444 8 8 0,000 8,941E-03 0,02619782 ! regulation of interleukin-8 biosynthetic process GO:0045414 9 8 0,000 8,941E-03 0,02617679 ! regulation of pigmentation during development GO:0048070 11 8 0,000 8,941E-03 0,0261558 ! macrophage activation GO:0042116 8 8 0,000 8,941E-03 0,02613484 ! poly(A) RNA binding GO:0008143 8 8 0,000 8,941E-03 0,02611392 ! positive regulation of insulin secretion GO:0032024 10 8 0,000 8,941E-03 0,02609303 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 18 8 0,000 8,941E-03 0,02607217 ! asymmetric protein localization GO:0008105 9 8 0,000 8,941E-03 0,02605134 ! nucleotide-sugar transmembrane transporter activity GO:0005338 8 8 0,000 8,941E-03 0,02603055 ! neurotrophin binding GO:0043121 10 8 0,000 8,941E-03 0,0260098 ! nucleoside transmembrane transporter activity GO:0005337 9 8 0,000 8,941E-03 0,02598907 ! positive regulation of multicellular organismal metabolic process GO:0044253 9 8 0,000 8,941E-03 0,02596838 ! phagocytosis, engulfment GO:0006911 10 8 0,000 8,941E-03 0,02594772 ! UDP-glucosyltransferase activity GO:0035251 8 8 0,000 8,941E-03 0,02592709 ! neurotransmitter biosynthetic process GO:0042136 9 8 0,000 8,941E-03 0,0259065 ! UV protection GO:0009650 9 8 0,000 8,941E-03 0,02588594 ! peptidyl-proline dioxygenase activity GO:0031543 8 8 0,000 8,941E-03 0,02586541 ! eukaryotic translation initiation factor 4F complex GO:0016281 10 8 0,000 8,941E-03 0,02584492 ! glutathione peroxidase activity GO:0004602 17 8 0,000 8,941E-03 0,02582445 ! acyl-CoA thioesterase activity GO:0016291 10 8 0,000 8,941E-03 0,02580402 ! ATP-binding cassette (ABC) transporter complex GO:0043190 8 8 0,000 8,941E-03 0,02578362 ! ferric iron binding GO:0008199 9 8 0,000 8,941E-03 0,02576326 ! response to UV-B GO:0010224 10 8 0,000 8,941E-03 0,02574292 ! intermediate filament organization GO:0045109 8 8 0,000 8,941E-03 0,02572262 ! protein-glutamine gamma-glutamyltransferase activity GO:0003810 8 8 0,000 8,941E-03 0,02570235 ! cellular extravasation GO:0045123 9 8 0,000 8,941E-03 0,02568211 ! skeletal muscle contraction GO:0003009 8 8 0,000 8,941E-03 0,02566191 ! positive regulation of cytokine production during immune response GO:0002720 8 8 0,000 8,941E-03 0,02564173 ! regulation of fatty acid biosynthetic process GO:0042304 17 8 0,000 8,941E-03 0,02562159 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 8,941E-03 0,02560148 ! antigen processing and presentation of endogenous antigen GO:0019883 8 8 0,000 8,941E-03 0,0255814 ! positive regulation of systemic arterial blood pressure GO:0003084 10 8 0,000 8,941E-03 0,02556135 ! negative regulation of systemic arterial blood pressure GO:0003085 9 8 0,000 8,941E-03 0,02554133 ! respiratory chain complex IV assembly GO:0008535 8 8 0,000 8,941E-03 0,02552135 ! erythrocyte development GO:0048821 9 8 0,000 8,941E-03 0,02550139 ! regulation of interleukin-10 production GO:0032653 8 8 0,000 8,941E-03 0,02548147 ! ribosome assembly GO:0042255 8 8 0,000 8,941E-03 0,02546158 ! postreplication repair GO:0006301 19 8 0,000 8,941E-03 0,02544172 ! gamma-tubulin binding GO:0043015 8 8 0,000 8,941E-03 0,02542189 ! NADPH oxidase complex GO:0043020 8 8 0,000 8,941E-03 0,02540209 ! mRNA cleavage GO:0006379 9 8 0,000 8,941E-03 0,02538232 ! UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity GO:0008499 9 8 0,000 8,941E-03 0,02536258 ! opioid receptor activity GO:0004985 8 8 0,000 8,941E-03 0,02534288 ! zymogen activation GO:0031638 9 8 0,000 8,941E-03 0,0253232 ! coenzyme A metabolic process GO:0015936 8 8 0,000 8,941E-03 0,02530356 ! cellular metabolic compound salvage GO:0043094 11 8 0,000 8,941E-03 0,02528394 ! costamere GO:0043034 8 8 0,000 8,941E-03 0,02526436 ! inositol trisphosphate kinase activity GO:0051766 9 8 0,000 8,941E-03 0,0252448 ! positive regulation of acute inflammatory response GO:0002675 8 8 0,000 8,941E-03 0,02522528 ! sarcomere organization GO:0045214 9 8 0,000 8,941E-03 0,02520578 ! wide pore channel activity GO:0022829 9 8 0,000 8,941E-03 0,02518632 ! ligand-regulated transcription factor activity GO:0003706 10 8 0,000 8,941E-03 0,02516689 ! RNA polymerase III transcription factor activity GO:0003709 8 8 0,000 8,941E-03 0,02514748 ! hormone catabolic process GO:0042447 9 8 0,000 8,941E-03 0,02512811 ! mRNA 3'-UTR binding GO:0003730 9 8 0,000 8,941E-03 0,02510876 ! cGMP biosynthetic process GO:0006182 9 8 0,000 8,941E-03 0,02508945 ! lysozyme activity GO:0003796 10 8 0,000 8,941E-03 0,02507016 ! death receptor binding GO:0005123 8 8 0,000 8,941E-03 0,02505091 ! protein modification by small protein removal GO:0070646 9 8 0,000 8,941E-03 0,02503168 ! adult feeding behavior GO:0008343 9 8 0,000 8,941E-03 0,02501249 ! microtubule basal body GO:0005932 8 8 0,000 8,941E-03 0,02499332 ! pyrimidine nucleotide catabolic process GO:0006244 8 8 0,000 8,941E-03 0,02497418 ! interleukin-1 receptor binding GO:0005149 9 8 0,000 8,941E-03 0,02495508 ! calcium-release channel activity GO:0015278 8 8 0,000 8,941E-03 0,024936 ! positive regulation of smooth muscle contraction GO:0045987 9 8 0,000 8,941E-03 0,02491695 ! behavioral response to nicotine GO:0035095 9 8 0,000 8,941E-03 0,02489793 ! aldehyde dehydrogenase (NAD) activity GO:0004029 9 8 0,000 8,941E-03 0,02487893 ! adenosine deaminase activity GO:0004000 8 8 0,000 8,941E-03 0,02485997 ! NAD biosynthetic process GO:0009435 9 8 0,000 8,941E-03 0,02484104 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 10 9 0,000 0,01005311 0,02791 ! positive regulation of glycogen biosynthetic process GO:0045725 9 9 0,000 0,01005311 0,02788877 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 10 9 0,000 0,01005311 0,02786758 ! sodium:hydrogen antiporter activity GO:0015385 9 9 0,000 0,01005311 0,02784642 GO:0005451|monovalent cation:hydrogen antiporter activity, ! cGMP metabolic process GO:0046068 10 9 0,000 0,01005311 0,02782529 ! myotube differentiation GO:0014902 9 9 0,000 0,01005311 0,0278042 ! folic acid and derivative biosynthetic process GO:0009396 9 9 0,000 0,01005311 0,02778313 ! N-glycan processing GO:0006491 10 9 0,000 0,01005311 0,0277621 ! regulation of epidermal growth factor receptor activity GO:0007176 11 9 0,000 0,01005311 0,0277411 ! actin-myosin filament sliding GO:0033275 11 9 0,000 0,01005311 0,02772013 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! axon part GO:0033267 12 9 0,000 0,01005311 0,0276992 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 10 9 0,000 0,01005311 0,02767829 ! RNA methylation GO:0001510 9 9 0,000 0,01005311 0,02765742 ! prostaglandin biosynthetic process GO:0001516 9 9 0,000 0,01005311 0,02763658 GO:0046457|prostanoid biosynthetic process, ! negative regulation of gene-specific transcription GO:0032582 10 9 0,000 0,01005311 0,02761577 ! artery development GO:0060840 9 9 0,000 0,01005311 0,02759499 GO:0048844|artery morphogenesis, ! axonemal dynein complex GO:0005858 9 9 0,000 0,01005311 0,02757424 ! regulation of postsynaptic membrane potential GO:0060078 11 9 0,000 0,01005311 0,02755352 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 9 9 0,000 0,01005311 0,02753284 ! auditory receptor cell differentiation GO:0042491 10 9 0,000 0,01005311 0,02751218 ! positive regulation of heart contraction GO:0045823 11 9 0,000 0,01005311 0,02749156 ! lipopolysaccharide binding GO:0001530 9 9 0,000 0,01005311 0,02747096 ! regulated secretory pathway GO:0045055 10 9 0,000 0,01005311 0,0274504 ! estrogen receptor binding GO:0030331 9 9 0,000 0,01005311 0,02742987 ! inner mitochondrial membrane organization GO:0007007 10 9 0,000 0,01005311 0,02740937 ! telomere maintenance via telomerase GO:0007004 20 9 0,000 0,01005311 0,0273889 GO:0006278|RNA-dependent DNA replication, ! L-phenylalanine metabolic process GO:0006558 9 9 0,000 0,01005311 0,02736846 GO:0006559|L-phenylalanine catabolic process, ! indolalkylamine metabolic process GO:0006586 9 9 0,000 0,01005311 0,02734805 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 9 9 0,000 0,01005311 0,02732767 ! urea metabolic process GO:0019627 19 9 0,000 0,01005311 0,02730732 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! smooth endoplasmic reticulum GO:0005790 11 9 0,000 0,01005311 0,02728701 ! autophagic vacuole GO:0005776 11 9 0,000 0,01005311 0,02726672 ! Rac GTPase binding GO:0048365 10 9 0,000 0,01005311 0,02724646 ! response to dietary excess GO:0002021 9 9 0,000 0,01005311 0,02722623 ! regulation of sodium ion transport GO:0002028 10 9 0,000 0,01005311 0,02720604 ! positive regulation of calcium ion transport into cytosol GO:0010524 13 9 0,000 0,01005311 0,02718587 ! lens development in camera-type eye GO:0002088 9 9 0,000 0,01005311 0,02716573 ! male sex determination GO:0030238 9 9 0,000 0,01005311 0,02714562 ! positive regulation of vasodilation GO:0045909 19 9 0,000 0,01005311 0,02712554 ! positive regulation of muscle contraction GO:0045933 11 9 0,000 0,01005311 0,0271055 ! regulation of smoothened signaling pathway GO:0008589 11 9 0,000 0,01005311 0,02708548 ! male germ cell nucleus GO:0001673 11 9 0,000 0,01005311 0,02706549 ! negative regulation of foam cell differentiation GO:0010745 12 9 0,000 0,01005311 0,02704553 ! copper ion homeostasis GO:0055070 9 9 0,000 0,01005311 0,0270256 ! protein heterooligomerization GO:0051291 10 9 0,000 0,01005311 0,0270057 ! cardiac muscle cell differentiation GO:0055007 12 9 0,000 0,01005311 0,02698583 ! purine nucleoside triphosphate catabolic process GO:0009146 9 9 0,000 0,01005311 0,02696598 ! synaptic vesicle exocytosis GO:0016079 10 9 0,000 0,01005311 0,02694617 ! regulation of B cell differentiation GO:0045577 10 9 0,000 0,01005311 0,02692639 ! cell differentiation in hindbrain GO:0021533 10 9 0,000 0,01005311 0,02690663 ! neural tube patterning GO:0021532 10 9 0,000 0,01005311 0,0268869 ! fucose catabolic process GO:0019317 10 9 0,000 0,01005311 0,02686721 GO:0042355|L-fucose catabolic process, ! retinal ganglion cell axon guidance GO:0031290 10 9 0,000 0,01005311 0,02684754 ! regulation of hormone metabolic process GO:0032350 12 9 0,000 0,01005311 0,0268279 ! sterol catabolic process GO:0016127 10 9 0,000 0,01005311 0,02680829 GO:0006707|cholesterol catabolic process, ! oligosaccharyl transferase activity GO:0004576 9 9 0,000 0,01005311 0,0267887 ! clathrin coat of coated pit GO:0030132 11 9 0,000 0,01005311 0,02676915 ! SNARE complex GO:0031201 11 9 0,000 0,01005311 0,02674963 ! negative regulation of osteoclast differentiation GO:0045671 10 9 0,000 0,01005311 0,02673013 ! negative regulation of glucose transport GO:0010829 10 9 0,000 0,01005311 0,02671066 ! methionine biosynthetic process GO:0009086 11 9 0,000 0,01005311 0,02669122 ! peptidoglycan binding GO:0042834 9 9 0,000 0,01005311 0,02667181 ! serine family amino acid biosynthetic process GO:0009070 10 9 0,000 0,01005311 0,02665242 ! somatic diversification of immunoglobulins during immune response GO:0002208 9 9 0,000 0,01005311 0,02663307 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! nicotinamide nucleotide biosynthetic process GO:0019359 10 9 0,000 0,01005311 0,02661374 ! intramolecular oxidoreductase activity, transposing S-S bonds GO:0016864 9 9 0,000 0,01005311 0,02659444 GO:0003756|protein disulfide isomerase activity, ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor GO:0016884 9 9 0,000 0,01005311 0,02657517 ! beta-1,3-galactosyltransferase activity GO:0048531 10 9 0,000 0,01005311 0,02655593 ! detection of bacterium GO:0016045 10 9 0,000 0,01005311 0,02653671 ! lymphocyte activation during immune response GO:0002285 9 9 0,000 0,01005311 0,02651752 ! embryonic gut development GO:0048566 10 9 0,000 0,01005311 0,02649836 ! hydrolase activity, acting on ether bonds GO:0016801 10 9 0,000 0,01005311 0,02647923 ! desmosome GO:0030057 10 9 0,000 0,01005311 0,02646013 ! long-chain-fatty-acid-CoA ligase activity GO:0004467 9 9 0,000 0,01005311 0,02644105 ! T cell receptor signaling pathway GO:0050852 14 9 0,000 0,01005311 0,026422 ! positive regulation of calcium-mediated signaling GO:0050850 11 9 0,000 0,01005311 0,02640298 ! actin filament polymerization GO:0030041 10 9 0,000 0,01005311 0,02638398 ! negative regulation of B cell activation GO:0050869 10 9 0,000 0,01005311 0,02636502 ! establishment of cell polarity GO:0030010 10 9 0,000 0,01005311 0,02634608 ! regulation of synapse organization GO:0050807 10 9 0,000 0,01005311 0,02632716 ! septin complex GO:0031105 10 9 0,000 0,01005311 0,02630828 GO:0032156|septin cytoskeleton, ! cholesterol transporter activity GO:0017127 9 9 0,000 0,01005311 0,02628942 ! anchoring collagen GO:0030934 9 9 0,000 0,01005311 0,02627058 ! defense response to Gram-negative bacterium GO:0050829 10 9 0,000 0,01005311 0,02625178 ! regulation of developmental growth GO:0048638 11 9 0,000 0,01005311 0,026233 ! negative regulation of smooth muscle cell proliferation GO:0048662 10 9 0,000 0,01005311 0,02621425 ! GMP binding GO:0019002 11 9 0,000 0,01005311 0,02619553 GO:0030553|cGMP binding, ! photoreceptor activity GO:0009881 10 9 0,000 0,01005311 0,02617683 ! virus-host interaction GO:0019048 13 9 0,000 0,01005311 0,02615816 ! pentose-phosphate shunt GO:0006098 11 9 0,000 0,01005311 0,02613951 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 9 9 0,000 0,01005311 0,0261209 ! negative regulation of lipid catabolic process GO:0050995 11 9 0,000 0,01005311 0,0261023 ! non-recombinational repair GO:0000726 10 9 0,000 0,01005311 0,02608374 GO:0006303|double-strand break repair via nonhomologous end joining, ! cell volume homeostasis GO:0006884 10 9 0,000 0,01005311 0,0260652 ! nuclear telomere cap complex GO:0000783 10 9 0,000 0,01005311 0,02604669 GO:0000782|telomere cap complex, ! activin binding GO:0048185 10 9 0,000 0,01005311 0,0260282 ! social behavior GO:0035176 10 9 0,000 0,01005311 0,02600974 ! regulation of positive chemotaxis GO:0050926 11 9 0,000 0,01005311 0,02599131 GO:0050927|positive regulation of positive chemotaxis, ! perikaryon GO:0043204 11 9 0,000 0,01005311 0,0259729 ! nitric oxide biosynthetic process GO:0006809 10 9 0,000 0,01005311 0,02595452 ! mating GO:0007618 11 9 0,000 0,01005311 0,02593616 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 9 0,000 0,01005311 0,02591784 ! rhythmic behavior GO:0007622 11 9 0,000 0,01005311 0,02589953 ! phospholipid efflux GO:0033700 10 9 0,000 0,01005311 0,02588125 ! cytoplasmic sequestering of transcription factor GO:0042994 9 9 0,000 0,01005311 0,025863 ! poly-purine tract binding GO:0070717 9 9 0,000 0,01005311 0,02584478 ! T cell proliferation GO:0042098 10 9 0,000 0,01005311 0,02582658 ! retinol dehydrogenase activity GO:0004745 9 9 0,000 0,01005311 0,0258084 ! negative regulation of cell-matrix adhesion GO:0001953 10 9 0,000 0,01005311 0,02579025 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 9 9 0,000 0,01005311 0,02577213 ! interleukin-1 binding GO:0019966 10 9 0,000 0,01005311 0,02575403 ! glucosyltransferase activity GO:0046527 9 9 0,000 0,01005311 0,02573596 ! platelet-derived growth factor receptor signaling pathway GO:0048008 14 9 0,000 0,01005311 0,02571791 ! cyclic nucleotide-dependent protein kinase activity GO:0004690 11 9 0,000 0,01005311 0,02569989 ! ovulation GO:0030728 9 9 0,000 0,01005311 0,02568189 ! acid phosphatase activity GO:0003993 18 9 0,000 0,01005311 0,02566392 ! embryonic cranial skeleton morphogenesis GO:0048701 10 9 0,000 0,01005311 0,02564597 ! ER overload response GO:0006983 11 9 0,000 0,01005311 0,02562805 ! B cell proliferation GO:0042100 10 9 0,000 0,01005311 0,02561015 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 11 9 0,000 0,01005311 0,02559228 ! calcium-transporting ATPase activity GO:0005388 11 9 0,000 0,01005311 0,02557443 ! mannose metabolic process GO:0006013 13 9 0,000 0,01005311 0,02555661 ! lipid digestion GO:0044241 11 9 0,000 0,01005311 0,02553881 ! tumor necrosis factor binding GO:0043120 9 9 0,000 0,01005311 0,02552104 ! tRNA methyltransferase activity GO:0008175 9 9 0,000 0,01005311 0,02550329 ! regulation of bone resorption GO:0045124 10 9 0,000 0,01005311 0,02548557 ! brain morphogenesis GO:0048854 9 9 0,000 0,01005311 0,02546787 ! positive regulation of alpha-beta T cell differentiation GO:0046638 10 9 0,000 0,01005311 0,0254502 ! 1-acylglycerol-3-phosphate O-acyltransferase activity GO:0003841 10 9 0,000 0,01005311 0,02543255 ! synaptic vesicle membrane GO:0030672 9 9 0,000 0,01005311 0,02541492 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 9 0,000 0,01005311 0,02539732 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 9 9 0,000 0,01005311 0,02537975 ! kinesin binding GO:0019894 9 9 0,000 0,01005311 0,0253622 ! multicellular organismal aging GO:0010259 18 9 0,000 0,01005311 0,02534467 ! Ran GTPase binding GO:0008536 11 9 0,000 0,01005311 0,02532717 ! ribosomal small subunit biogenesis GO:0042274 9 9 0,000 0,01005311 0,02530969 ! protein import into peroxisome matrix GO:0016558 9 9 0,000 0,01005311 0,02529223 ! mRNA polyadenylation GO:0006378 10 9 0,000 0,01005311 0,0252748 ! neuropeptide Y receptor activity GO:0004983 10 9 0,000 0,01005311 0,02525739 ! mannosyl-oligosaccharide mannosidase activity GO:0015924 14 9 0,000 0,01005311 0,02524001 ! prostaglandin receptor activity GO:0004955 11 9 0,000 0,01005311 0,02522265 ! caspase inhibitor activity GO:0043027 9 9 0,000 0,01005311 0,02520532 ! adrenoceptor activity GO:0004935 12 9 0,000 0,01005311 0,02518801 ! regulation of isotype switching GO:0045191 9 9 0,000 0,01005311 0,02517072 ! positive regulation of leukocyte migration GO:0002687 10 9 0,000 0,01005311 0,02515345 ! transmembrane receptor protein tyrosine kinase signaling protein activity GO:0005066 10 9 0,000 0,01005311 0,02513621 ! positive regulation of ATPase activity GO:0032781 11 9 0,000 0,01005311 0,025119 ! nonprotein amino acid metabolic process GO:0019794 19 9 0,000 0,01005311 0,0251018 ! ionotropic glutamate receptor complex GO:0008328 14 9 0,000 0,01005311 0,02508464 ! Notch binding GO:0005112 10 9 0,000 0,01005311 0,02506749 ! ATPase regulator activity GO:0060590 10 9 0,000 0,01005311 0,02505037 ! gamma-tubulin complex GO:0000930 19 9 0,000 0,01005311 0,02503327 ! pyrimidine base metabolic process GO:0006206 10 9 0,000 0,01005311 0,02501619 ! establishment or maintenance of apical/basal cell polarity GO:0035088 10 9 0,000 0,01005311 0,02499914 ! tubulin-tyrosine ligase activity GO:0004835 10 9 0,000 0,01005311 0,02498211 ! alcohol dehydrogenase (NAD) activity GO:0004022 10 9 0,000 0,01005311 0,0249651 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 12 10 0,000 0,01116416 0,02770534 ! oligosaccharide biosynthetic process GO:0009312 10 10 0,000 0,01116416 0,02768651 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 11 10 0,000 0,01116416 0,0276677 ! sleep GO:0030431 11 10 0,000 0,01116416 0,02764892 ! positive regulation of lipid biosynthetic process GO:0046889 10 10 0,000 0,01116416 0,02763016 ! lipid particle GO:0005811 10 10 0,000 0,01116416 0,02761143 ! filopodium assembly GO:0046847 14 10 0,000 0,01116416 0,02759272 ! UTP metabolic process GO:0046051 12 10 0,000 0,01116416 0,02757404 GO:0004550|nucleoside diphosphate kinase activity, GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! Wnt receptor signaling pathway through beta-catenin GO:0060070 13 10 0,000 0,01116416 0,02755538 ! guanylate kinase activity GO:0004385 14 10 0,000 0,01116416 0,02753675 ! integral to mitochondrial membrane GO:0032592 10 10 0,000 0,01116416 0,02751814 ! COPI coating of Golgi vesicle GO:0048205 11 10 0,000 0,01116416 0,02749956 GO:0048200|Golgi transport vesicle coating, ! platelet alpha granule membrane GO:0031092 11 10 0,000 0,01116416 0,02748101 ! macromolecule transmembrane transporter activity GO:0022884 11 10 0,000 0,01116416 0,02746248 GO:0015450|P-P-bond-hydrolysis-driven protein transmembrane transporter activity, ! estradiol 17-beta-dehydrogenase activity GO:0004303 11 10 0,000 0,01116416 0,02744397 ! thyroid hormone receptor coactivator activity GO:0030375 11 10 0,000 0,01116416 0,02742549 GO:0010861|thyroid hormone receptor activator activity, ! regulation of receptor activity GO:0010469 12 10 0,000 0,01116416 0,02740703 ! lung alveolus development GO:0048286 11 10 0,000 0,01116416 0,0273886 ! regulation of chemokine biosynthetic process GO:0045073 11 10 0,000 0,01116416 0,0273702 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,01116416 0,02735182 ! negative regulation of striated muscle development GO:0045843 11 10 0,000 0,01116416 0,02733346 ! oxidoreductase activity, acting on NADH or NADPH, with oxygen as acceptor GO:0050664 10 10 0,000 0,01116416 0,02731513 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 11 10 0,000 0,01116416 0,02729682 ! regulation of mRNA processing GO:0050684 12 10 0,000 0,01116416 0,02727853 ! positive regulation of survival gene product expression GO:0045885 12 10 0,000 0,01116416 0,02726028 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 11 10 0,000 0,01116416 0,02724204 ! transforming growth factor beta binding GO:0050431 11 10 0,000 0,01116416 0,02722383 ! histidine metabolic process GO:0006547 10 10 0,000 0,01116416 0,02720565 GO:0009075|histidine family amino acid metabolic process, ! glucan biosynthetic process GO:0009250 10 10 0,000 0,01116416 0,02718749 GO:0005978|glycogen biosynthetic process, ! endosome organization GO:0007032 13 10 0,000 0,01116416 0,02716935 ! death receptor activity GO:0005035 11 10 0,000 0,01116416 0,02715124 ! mitochondrial inner membrane presequence translocase complex GO:0005744 11 10 0,000 0,01116416 0,02713315 ! entry into host cell GO:0030260 11 10 0,000 0,01116416 0,02711508 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! protein kinase A binding GO:0051018 10 10 0,000 0,01116416 0,02709704 ! filamentous actin GO:0031941 11 10 0,000 0,01116416 0,02707902 ! behavioral fear response GO:0001662 12 10 0,000 0,01116416 0,02706103 GO:0002209|behavioral defense response, ! bone mineralization GO:0030282 12 10 0,000 0,01116416 0,02704306 ! negative regulation of ossification GO:0030279 12 10 0,000 0,01116416 0,02702512 ! phosphatidylcholine biosynthetic process GO:0006656 11 10 0,000 0,01116416 0,0270072 ! macrophage differentiation GO:0030225 11 10 0,000 0,01116416 0,0269893 ! positive regulation of phagocytosis GO:0050766 11 10 0,000 0,01116416 0,02697143 ! recycling endosome membrane GO:0055038 11 10 0,000 0,01116416 0,02695358 ! regulation of fat cell differentiation GO:0045598 11 10 0,000 0,01116416 0,02693575 ! snRNA metabolic process GO:0016073 10 10 0,000 0,01116416 0,02691795 GO:0016180|snRNA processing, ! glycosphingolipid biosynthetic process GO:0006688 11 10 0,000 0,01116416 0,02690017 ! purine ribonucleotide catabolic process GO:0009154 10 10 0,000 0,01116416 0,02688241 ! positive regulation of Ras GTPase activity GO:0032320 14 10 0,000 0,01116416 0,02686468 ! immunoglobulin production during immune response GO:0002381 10 10 0,000 0,01116416 0,02684697 ! nitric oxide metabolic process GO:0046209 20 10 0,000 0,01116416 0,02682928 ! induction of an organ GO:0001759 12 10 0,000 0,01116416 0,02681162 ! response to estradiol stimulus GO:0032355 11 10 0,000 0,01116416 0,02679398 ! synaptic vesicle endocytosis GO:0048488 12 10 0,000 0,01116416 0,02677637 ! negative regulation of MAPKKK cascade GO:0043409 12 10 0,000 0,01116416 0,02675877 ! positive regulation of interleukin-1 beta secretion GO:0050718 11 10 0,000 0,01116416 0,0267412 ! MHC class II receptor activity GO:0032395 14 10 0,000 0,01116416 0,02672366 ! peptidyl-lysine modification GO:0018205 11 10 0,000 0,01116416 0,02670613 ! ribonuclease P activity GO:0004526 10 10 0,000 0,01116416 0,02668863 ! COPI vesicle coat GO:0030126 12 10 0,000 0,01116416 0,02667115 GO:0030663|COPI coated vesicle membrane, ! telomere maintenance via telomere lengthening GO:0010833 21 10 0,000 0,01116416 0,0266537 ! vitamin transporter activity GO:0051183 12 10 0,000 0,01116416 0,02663627 ! snRNA binding GO:0017069 11 10 0,000 0,01116416 0,02661886 ! negative regulation of osteoblast differentiation GO:0045668 12 10 0,000 0,01116416 0,02660147 ! heparan sulfate sulfotransferase activity GO:0034483 10 10 0,000 0,01116416 0,02658411 ! fatty-acid ligase activity GO:0015645 10 10 0,000 0,01116416 0,02656677 ! intramolecular transferase activity, phosphotransferases GO:0016868 11 10 0,000 0,01116416 0,02654945 ! quaternary ammonium group transport GO:0015697 10 10 0,000 0,01116416 0,02653215 ! intramolecular oxidoreductase activity, interconverting keto- and enol-groups GO:0016862 10 10 0,000 0,01116416 0,02651488 ! metalloenzyme inhibitor activity GO:0048551 11 10 0,000 0,01116416 0,02649763 GO:0008191|metalloendopeptidase inhibitor activity, GO:0010576|metalloenzyme regulator activity, ! anterior/posterior axis specification GO:0009948 14 10 0,000 0,01116416 0,0264804 ! regulation of RNA splicing GO:0043484 13 10 0,000 0,01116416 0,02646319 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines GO:0016813 10 10 0,000 0,01116416 0,02644601 ! trophectodermal cell differentiation GO:0001829 11 10 0,000 0,01116416 0,02642885 ! extracellular matrix binding GO:0050840 11 10 0,000 0,01116416 0,02641171 ! regulation of synapse structure and activity GO:0050803 11 10 0,000 0,01116416 0,02639459 ! autophagic vacuole formation GO:0000045 11 10 0,000 0,01116416 0,0263775 ! clathrin-coated endocytic vesicle GO:0045334 10 10 0,000 0,01116416 0,02636042 ! negative regulation of cell projection organization GO:0031345 14 10 0,000 0,01116416 0,02634337 ! negative regulation of cellular catabolic process GO:0031330 11 10 0,000 0,01116416 0,02632634 ! rough endoplasmic reticulum membrane GO:0030867 10 10 0,000 0,01116416 0,02630934 ! thyroid gland development GO:0030878 12 10 0,000 0,01116416 0,02629235 ! DNA bending activity GO:0008301 11 10 0,000 0,01116416 0,02627539 ! regulation of phosphatase activity GO:0010921 10 10 0,000 0,01116416 0,02625845 ! neutral lipid biosynthetic process GO:0046460 10 10 0,000 0,01116416 0,02624153 GO:0046463|acylglycerol biosynthetic process, ! embryonic hindlimb morphogenesis GO:0035116 11 10 0,000 0,01116416 0,02622463 ! embryonic forelimb morphogenesis GO:0035115 12 10 0,000 0,01116416 0,02620776 ! regulation of glucan biosynthetic process GO:0010962 10 10 0,000 0,01116416 0,0261909 GO:0005979|regulation of glycogen biosynthetic process, GO:0032885|regulation of polysaccharide biosynthetic process, ! secondary active sulfate transmembrane transporter activity GO:0008271 11 10 0,000 0,01116416 0,02617407 ! regulation of glycolysis GO:0006110 11 10 0,000 0,01116416 0,02615726 ! nucleotidase activity GO:0008252 10 10 0,000 0,01116416 0,02614047 ! phosphatidylinositol phosphate kinase activity GO:0016307 11 10 0,000 0,01116416 0,0261237 ! dipeptidyl-peptidase activity GO:0008239 12 10 0,000 0,01116416 0,02610696 ! androgen metabolic process GO:0008209 11 10 0,000 0,01116416 0,02609023 ! lateral plasma membrane GO:0016328 13 10 0,000 0,01116416 0,02607353 ! cation:amino acid symporter activity GO:0005416 12 10 0,000 0,01116416 0,02605685 ! startle response GO:0001964 13 10 0,000 0,01116416 0,02604019 ! amyloid precursor protein metabolic process GO:0042982 12 10 0,000 0,01116416 0,02602355 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 12 10 0,000 0,01116416 0,02600693 ! positive regulation of endothelial cell proliferation GO:0001938 13 10 0,000 0,01116416 0,02599033 ! 3'-5'-exoribonuclease activity GO:0000175 10 10 0,000 0,01116416 0,02597376 ! spinal cord patterning GO:0021511 12 10 0,000 0,01116416 0,0259572 ! peptide or protein amino-terminal blocking GO:0018409 11 10 0,000 0,01116416 0,02594067 ! MAP kinase tyrosine/serine/threonine phosphatase activity GO:0017017 10 10 0,000 0,01116416 0,02592416 GO:0033549|MAP kinase phosphatase activity, ! response to X-ray GO:0010165 11 10 0,000 0,01116416 0,02590767 ! embryonic eye morphogenesis GO:0048048 14 10 0,000 0,01116416 0,0258912 ! sodium:potassium-exchanging ATPase activity GO:0005391 12 10 0,000 0,01116416 0,02587475 ! zinc ion transmembrane transporter activity GO:0005385 13 10 0,000 0,01116416 0,02585832 ! positive regulation of glycogen metabolic process GO:0070875 11 10 0,000 0,01116416 0,02584191 ! glucose transmembrane transporter activity GO:0005355 10 10 0,000 0,01116416 0,02582552 ! regulation of intracellular pH GO:0051453 10 10 0,000 0,01116416 0,02580916 ! retrograde transport, endosome to Golgi GO:0042147 12 10 0,000 0,01116416 0,02579281 ! regulation of multicellular organismal metabolic process GO:0044246 11 10 0,000 0,01116416 0,02577649 ! adult heart development GO:0007512 14 10 0,000 0,01116416 0,02576019 ! neuromuscular junction development GO:0007528 12 10 0,000 0,01116416 0,0257439 ! carbohydrate phosphatase activity GO:0019203 11 10 0,000 0,01116416 0,02572764 ! O-methyltransferase activity GO:0008171 10 10 0,000 0,01116416 0,0257114 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 10 10 0,000 0,01116416 0,02569518 ! signalosome GO:0008180 10 10 0,000 0,01116416 0,02567897 ! lysophospholipase activity GO:0004622 19 10 0,000 0,01116416 0,02566279 ! prefoldin complex GO:0016272 10 10 0,000 0,01116416 0,02564663 ! alpha-beta T cell differentiation GO:0046632 12 10 0,000 0,01116416 0,02563049 ! negative regulation of insulin receptor signaling pathway GO:0046627 12 10 0,000 0,01116416 0,02561437 ! positive regulation of T cell mediated immunity GO:0002711 10 10 0,000 0,01116416 0,02559827 ! nucleoside bisphosphate metabolic process GO:0033865 10 10 0,000 0,01116416 0,02558219 ! endocytic vesicle membrane GO:0030666 10 10 0,000 0,01116416 0,02556613 ! gland morphogenesis GO:0022612 11 10 0,000 0,01116416 0,0255501 ! icosanoid receptor activity GO:0004953 13 10 0,000 0,01116416 0,02553408 GO:0004954|prostanoid receptor activity, ! regulation of macrophage activation GO:0043030 11 10 0,000 0,01116416 0,02551808 ! peptide transporter activity GO:0015197 10 10 0,000 0,01116416 0,0255021 ! proton-transporting ATP synthase complex, coupling factor F(o) GO:0045263 10 10 0,000 0,01116416 0,02548614 ! regulation of leukocyte migration GO:0002685 11 10 0,000 0,01116416 0,0254702 ! muscle maintenance GO:0046716 10 10 0,000 0,01116416 0,02545428 ! acid secretion GO:0046717 12 10 0,000 0,01116416 0,02543838 ! retinoid-X receptor activity GO:0004886 11 10 0,000 0,01116416 0,0254225 ! catecholamine biosynthetic process GO:0042423 11 10 0,000 0,01116416 0,02540665 ! thyroid hormone metabolic process GO:0042403 11 10 0,000 0,01116416 0,02539081 ! GTPase inhibitor activity GO:0005095 21 10 0,000 0,01116416 0,02537499 ! somatic recombination of immunoglobulin gene segments GO:0016447 10 10 0,000 0,01116416 0,02535919 ! pattern recognition receptor activity GO:0008329 10 10 0,000 0,01116416 0,02534341 ! quinone cofactor metabolic process GO:0042375 11 10 0,000 0,01116416 0,02532764 ! regulation of organic acid transport GO:0032890 12 10 0,000 0,01116416 0,0253119 ! platelet-derived growth factor receptor binding GO:0005161 14 10 0,000 0,01116416 0,02529618 ! C-acyltransferase activity GO:0016408 12 10 0,000 0,01116416 0,02528048 ! cAMP-dependent protein kinase complex GO:0005952 12 10 0,000 0,01116416 0,0252648 ! water channel activity GO:0015250 15 10 0,000 0,01116416 0,02524913 ! phospholipase inhibitor activity GO:0004859 10 10 0,000 0,01116416 0,02523349 ! regulation of embryonic development GO:0045995 12 10 0,000 0,01116416 0,02521787 ! acrosome reaction GO:0007340 12 10 0,000 0,01116416 0,02520226 ! mitochondrion localization GO:0051646 10 10 0,000 0,01116416 0,02518667 ! cilium part GO:0044441 10 10 0,000 0,01116416 0,02517111 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 12 11 0,000 0,01227402 0,02765635 ! 'de novo' posttranslational protein folding GO:0051084 11 11 0,000 0,01227402 0,02763928 ! negative regulation of blood pressure GO:0045776 13 11 0,000 0,01227402 0,02762223 ! centriole GO:0005814 11 11 0,000 0,01227402 0,0276052 ! cadmium ion binding GO:0046870 15 11 0,000 0,01227402 0,02758819 ! hemoglobin complex GO:0005833 13 11 0,000 0,01227402 0,0275712 ! CTP metabolic process GO:0046036 13 11 0,000 0,01227402 0,02755424 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0009148|pyrimidine nucleoside triphosphate biosynthetic process, ! regulation of neurotransmitter secretion GO:0046928 12 11 0,000 0,01227402 0,02753729 ! response to pain GO:0048265 12 11 0,000 0,01227402 0,02752037 ! regulation of viral genome replication GO:0045069 13 11 0,000 0,01227402 0,02750346 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 11 11 0,000 0,01227402 0,02748658 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 12 11 0,000 0,01227402 0,02746972 ! nucleotide-sugar metabolic process GO:0009225 13 11 0,000 0,01227402 0,02745287 ! regulation of catecholamine secretion GO:0050433 12 11 0,000 0,01227402 0,02743605 ! low-density lipoprotein receptor activity GO:0005041 11 11 0,000 0,01227402 0,02741925 ! peptide antigen binding GO:0042605 14 11 0,000 0,01227402 0,02740247 ! polyamine metabolic process GO:0006595 11 11 0,000 0,01227402 0,02738571 ! lysosphingolipid and lysophosphatidic acid receptor activity GO:0001619 13 11 0,000 0,01227402 0,02736897 GO:0045125|bioactive lipid receptor activity, ! nucleobase biosynthetic process GO:0046112 13 11 0,000 0,01227402 0,02735225 ! regulation of calcium ion transport into cytosol GO:0010522 15 11 0,000 0,01227402 0,02733555 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 12 11 0,000 0,01227402 0,02731887 GO:0002717|positive regulation of natural killer cell mediated immunity, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 12 11 0,000 0,01227402 0,02730222 ! protein homotetramerization GO:0051289 13 11 0,000 0,01227402 0,02728558 ! regulation of gliogenesis GO:0014013 13 11 0,000 0,01227402 0,02726896 GO:0045685|regulation of glial cell differentiation, ! oligodendrocyte development GO:0014003 11 11 0,000 0,01227402 0,02725237 ! cytoskeletal adaptor activity GO:0008093 17 11 0,000 0,01227402 0,02723579 ! regulation of circadian rhythm GO:0042752 11 11 0,000 0,01227402 0,02721923 ! low-density lipoprotein receptor binding GO:0050750 11 11 0,000 0,01227402 0,02720269 ! response to dsRNA GO:0043331 21 11 0,000 0,01227402 0,02718618 ! response to amine stimulus GO:0014075 15 11 0,000 0,01227402 0,02716968 GO:0010243|response to organic nitrogen, ! embryonic axis specification GO:0000578 14 11 0,000 0,01227402 0,02715321 ! sphingomyelin metabolic process GO:0006684 13 11 0,000 0,01227402 0,02713675 ! cell wall macromolecule catabolic process GO:0016998 14 11 0,000 0,01227402 0,02712031 ! spinal cord motor neuron differentiation GO:0021522 12 11 0,000 0,01227402 0,0271039 ! retinal binding GO:0016918 11 11 0,000 0,01227402 0,0270875 ! leukocyte activation during immune response GO:0002366 11 11 0,000 0,01227402 0,02707112 GO:0002263|cell activation during immune response, ! regulation of sterol transport GO:0032371 12 11 0,000 0,01227402 0,02705476 GO:0032374|regulation of cholesterol transport, ! beta-tubulin binding GO:0048487 14 11 0,000 0,01227402 0,02703843 ! autonomic nervous system development GO:0048483 12 11 0,000 0,01227402 0,02702211 ! negative regulation of lipid transport GO:0032369 12 11 0,000 0,01227402 0,02700581 ! photoreceptor outer segment GO:0001750 12 11 0,000 0,01227402 0,02698953 ! positive regulation of interleukin-1 secretion GO:0050716 12 11 0,000 0,01227402 0,02697327 ! peptidyl-threonine modification GO:0018210 15 11 0,000 0,01227402 0,02695704 ! clathrin coat of trans-Golgi network vesicle GO:0030130 15 11 0,000 0,01227402 0,02694082 ! regulation of interleukin-1 beta secretion GO:0050706 12 11 0,000 0,01227402 0,02692462 ! regulation of epidermis development GO:0045682 14 11 0,000 0,01227402 0,02690844 ! positive regulation of pathway-restricted SMAD protein phosphorylation GO:0010862 11 11 0,000 0,01227402 0,02689227 ! midbrain development GO:0030901 12 11 0,000 0,01227402 0,02687613 ! musculoskeletal movement GO:0050881 12 11 0,000 0,01227402 0,02686001 GO:0050879|multicellular organismal movement, ! histone deacetylase binding GO:0042826 11 11 0,000 0,01227402 0,02684391 ! regulation of RNA stability GO:0043487 13 11 0,000 0,01227402 0,02682782 GO:0043488|regulation of mRNA stability, ! intramolecular oxidoreductase activity, transposing C=C bonds GO:0016863 11 11 0,000 0,01227402 0,02681176 ! cell killing GO:0001906 13 11 0,000 0,01227402 0,02679571 ! regulation of cellular carbohydrate catabolic process GO:0043471 13 11 0,000 0,01227402 0,02677969 GO:0043470|regulation of carbohydrate catabolic process, ! oocyte development GO:0048599 12 11 0,000 0,01227402 0,02676368 ! carbon-sulfur lyase activity GO:0016846 11 11 0,000 0,01227402 0,02674769 ! cerebellar cortex morphogenesis GO:0021696 13 11 0,000 0,01227402 0,02673172 ! regulation of blood vessel endothelial cell migration GO:0043535 13 11 0,000 0,01227402 0,02671577 ! folic acid binding GO:0005542 12 11 0,000 0,01227402 0,02669984 ! mRNA 3'-end processing GO:0031124 12 11 0,000 0,01227402 0,02668393 ! regulation of calcium-mediated signaling GO:0050848 13 11 0,000 0,01227402 0,02666804 ! positive regulation of protein polymerization GO:0032273 11 11 0,000 0,01227402 0,02665216 ! microspike assembly GO:0030035 15 11 0,000 0,01227402 0,02663631 ! lamellipodium assembly GO:0030032 22 11 0,000 0,01227402 0,02662047 ! fibrillar collagen GO:0005583 12 11 0,000 0,01227402 0,02660466 ! inner ear receptor cell differentiation GO:0060113 12 11 0,000 0,01227402 0,02658886 ! cytoplasmic sequestering of protein GO:0051220 12 11 0,000 0,01227402 0,02657308 ! negative regulation of muscle development GO:0048635 13 11 0,000 0,01227402 0,02655732 ! very-long-chain fatty acid metabolic process GO:0000038 12 11 0,000 0,01227402 0,02654157 ! synaptonemal complex GO:0000795 11 11 0,000 0,01227402 0,02652585 ! reproductive cellular process GO:0048610 13 11 0,000 0,01227402 0,02651015 ! cortical actin cytoskeleton organization GO:0030866 12 11 0,000 0,01227402 0,02649446 ! Golgi vesicle budding GO:0048194 12 11 0,000 0,01227402 0,02647879 ! response to cAMP GO:0051591 11 11 0,000 0,01227402 0,02646314 ! detection of mechanical stimulus GO:0050982 13 11 0,000 0,01227402 0,02644751 ! 1-phosphatidylinositol-3-kinase activity GO:0016303 13 11 0,000 0,01227402 0,0264319 ! regulation of cell projection assembly GO:0060491 11 11 0,000 0,01227402 0,0264163 ! negative regulation of transcription factor import into nucleus GO:0042992 11 11 0,000 0,01227402 0,02640073 ! positive regulation of transcription factor import into nucleus GO:0042993 13 11 0,000 0,01227402 0,02638517 ! macromolecular complex remodeling GO:0034367 11 11 0,000 0,01227402 0,02636963 GO:0034368|protein-lipid complex remodeling, GO:0034369|plasma lipoprotein particle remodeling, ! glycerol ether biosynthetic process GO:0046504 11 11 0,000 0,01227402 0,02635411 ! drug transport GO:0015893 12 11 0,000 0,01227402 0,02633861 ! FMN binding GO:0010181 12 11 0,000 0,01227402 0,02632313 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 11 0,000 0,01227402 0,02630766 ! water transporter activity GO:0005372 17 11 0,000 0,01227402 0,02629221 ! regulation of glycogen metabolic process GO:0070873 12 11 0,000 0,01227402 0,02627678 GO:0032881|regulation of polysaccharide metabolic process, ! substrate-bound cell migration GO:0006929 13 11 0,000 0,01227402 0,02626137 ! multicellular organism growth GO:0035264 12 11 0,000 0,01227402 0,02624598 ! integrator complex GO:0032039 11 11 0,000 0,01227402 0,0262306 ! L-glutamate transmembrane transporter activity GO:0005313 13 11 0,000 0,01227402 0,02621524 GO:0015172|acidic amino acid transmembrane transporter activity, ! DNA integration GO:0015074 11 11 0,000 0,01227402 0,0261999 ! brush border membrane GO:0031526 12 11 0,000 0,01227402 0,02618458 ! actin cytoskeleton reorganization GO:0031532 14 11 0,000 0,01227402 0,02616928 ! macroautophagy GO:0016236 12 11 0,000 0,01227402 0,02615399 ! protein disulfide oxidoreductase activity GO:0015035 11 11 0,000 0,01227402 0,02613872 ! neuromuscular junction GO:0031594 12 11 0,000 0,01227402 0,02612347 ! positive regulation of peptide secretion GO:0002793 13 11 0,000 0,01227402 0,02610824 ! positive regulation of alpha-beta T cell activation GO:0046635 12 11 0,000 0,01227402 0,02609303 ! organic anion transmembrane transporter activity GO:0008514 11 11 0,000 0,01227402 0,02607783 ! response to antibiotic GO:0046677 13 11 0,000 0,01227402 0,02606265 ! protein-hormone receptor activity GO:0016500 12 11 0,000 0,01227402 0,02604749 ! bile acid transmembrane transporter activity GO:0015125 13 11 0,000 0,01227402 0,02603235 ! proteasome accessory complex GO:0022624 11 11 0,000 0,01227402 0,02601722 ! neuroblast proliferation GO:0007405 13 11 0,000 0,01227402 0,02600211 ! non-G-protein coupled 7TM receptor activity GO:0004926 14 11 0,000 0,01227402 0,02598702 ! negative regulation of neurological system process GO:0031645 13 11 0,000 0,01227402 0,02597195 ! nitric oxide mediated signal transduction GO:0007263 12 11 0,000 0,01227402 0,02595689 ! protein kinase C binding GO:0005080 11 11 0,000 0,01227402 0,02594185 ! transforming growth factor beta receptor, cytoplasmic mediator activity GO:0005072 12 11 0,000 0,01227402 0,02592683 ! male genitalia development GO:0030539 15 11 0,000 0,01227402 0,02591183 ! receptor inhibitor activity GO:0030547 12 11 0,000 0,01227402 0,02589684 GO:0048019|receptor antagonist activity, ! estrogen receptor signaling pathway GO:0030520 12 11 0,000 0,01227402 0,02588187 ! L-fucose metabolic process GO:0042354 13 11 0,000 0,01227402 0,02586692 ! palmitoyltransferase activity GO:0016409 11 11 0,000 0,01227402 0,02585198 ! arylsulfatase activity GO:0004065 12 11 0,000 0,01227402 0,02583707 ! sterol transporter activity GO:0015248 11 11 0,000 0,01227402 0,02582217 ! response to nicotine GO:0035094 13 11 0,000 0,01227402 0,02580728 ! adenylate cyclase activity GO:0004016 11 11 0,000 0,01227402 0,02579242 ! rRNA transcription GO:0009303 12 12 0,000 0,0133827 0,02810598 ! ER-associated protein catabolic process GO:0030433 14 12 0,000 0,0133827 0,02808981 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of blood pressure GO:0045777 15 12 0,000 0,0133827 0,02807366 ! superoxide anion generation GO:0042554 12 12 0,000 0,0133827 0,02805752 ! pteridine and derivative biosynthetic process GO:0042559 22 12 0,000 0,0133827 0,02804141 ! regulation of S phase GO:0033261 16 12 0,000 0,0133827 0,02802531 ! regulation of chemokine production GO:0032642 13 12 0,000 0,0133827 0,02800923 ! male meiosis GO:0007140 12 12 0,000 0,0133827 0,02799317 ! signal complex assembly GO:0007172 15 12 0,000 0,0133827 0,02797713 ! positive regulation of GTPase activity GO:0043547 17 12 0,000 0,0133827 0,02796111 ! GTP metabolic process GO:0046039 14 12 0,000 0,0133827 0,0279451 ! retina morphogenesis in camera-type eye GO:0060042 16 12 0,000 0,0133827 0,02792911 ! hair follicle morphogenesis GO:0031069 14 12 0,000 0,0133827 0,02791315 ! voltage-gated sodium channel complex GO:0001518 15 12 0,000 0,0133827 0,02789719 GO:0034706|sodium channel complex, ! RNA polyadenylation GO:0043631 13 12 0,000 0,0133827 0,02788126 ! cartilage condensation GO:0001502 14 12 0,000 0,0133827 0,02786535 ! polysome GO:0005844 14 12 0,000 0,0133827 0,02784945 ! hippocampus development GO:0021766 13 12 0,000 0,0133827 0,02783358 ! lipoprotein receptor binding GO:0070325 13 12 0,000 0,0133827 0,02781772 ! beta-amyloid binding GO:0001540 12 12 0,000 0,0133827 0,02780187 ! negative regulation of endocytosis GO:0045806 15 12 0,000 0,0133827 0,02778605 ! regulation of interferon-gamma biosynthetic process GO:0045072 15 12 0,000 0,0133827 0,02777025 ! regulation of exit from mitosis GO:0007096 31 12 0,000 0,0133827 0,02775446 ! chylomicron GO:0042627 13 12 0,000 0,0133827 0,02773869 ! T cell selection GO:0045058 22 12 0,000 0,0133827 0,02772294 ! negative regulation of proteolysis GO:0045861 12 12 0,000 0,0133827 0,0277072 ! glycolipid biosynthetic process GO:0009247 13 12 0,000 0,0133827 0,02769149 ! WW domain binding GO:0050699 12 12 0,000 0,0133827 0,02767579 ! methionine metabolic process GO:0006555 14 12 0,000 0,0133827 0,02766011 ! nuclear heterochromatin GO:0005720 12 12 0,000 0,0133827 0,02764445 ! glycine metabolic process GO:0006544 14 12 0,000 0,0133827 0,0276288 ! plasma membrane organization GO:0007009 12 12 0,000 0,0133827 0,02761317 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,0133827 0,02759756 ! ribonucleotide catabolic process GO:0009261 12 12 0,000 0,0133827 0,02758197 ! Golgi organization GO:0007030 15 12 0,000 0,0133827 0,0275664 ! hydrogen ion transporting ATP synthase activity, rotational mechanism GO:0046933 12 12 0,000 0,0133827 0,02755084 ! mitotic spindle organization GO:0007052 13 12 0,000 0,0133827 0,0275353 ! integral to peroxisomal membrane GO:0005779 12 12 0,000 0,0133827 0,02751978 ! integral to membrane of membrane fraction GO:0000299 13 12 0,000 0,0133827 0,02750428 ! regulation of the force of heart contraction GO:0002026 13 12 0,000 0,0133827 0,02748879 ! temperature homeostasis GO:0001659 13 12 0,000 0,0133827 0,02747332 ! negative regulation of mitotic cell cycle GO:0045930 15 12 0,000 0,0133827 0,02745787 ! acyl-CoA metabolic process GO:0006637 12 12 0,000 0,0133827 0,02744243 ! lipoprotein receptor activity GO:0030228 12 12 0,000 0,0133827 0,02742702 ! cotranslational protein targeting to membrane GO:0006613 14 12 0,000 0,0133827 0,02741162 ! axon cargo transport GO:0008088 13 12 0,000 0,0133827 0,02739624 ! regulation of phagocytosis GO:0050764 14 12 0,000 0,0133827 0,02738087 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 14 12 0,000 0,0133827 0,02736552 ! nucleoside triphosphate catabolic process GO:0009143 12 12 0,000 0,0133827 0,02735019 ! transcription elongation factor complex GO:0008023 12 12 0,000 0,0133827 0,02733488 ! basal lamina GO:0005605 12 12 0,000 0,0133827 0,02731958 ! regulation of interleukin-1 secretion GO:0050704 13 12 0,000 0,0133827 0,0273043 ! pancreatic ribonuclease activity GO:0004522 12 12 0,000 0,0133827 0,02728904 ! tRNA-specific ribonuclease activity GO:0004549 12 12 0,000 0,0133827 0,02727379 ! biomineral formation GO:0031214 14 12 0,000 0,0133827 0,02725857 ! water homeostasis GO:0030104 12 12 0,000 0,0133827 0,02724335 ! promoter binding GO:0010843 14 12 0,000 0,0133827 0,02722816 ! regulation of erythrocyte differentiation GO:0045646 15 12 0,000 0,0133827 0,02721298 ! intestinal absorption GO:0050892 14 12 0,000 0,0133827 0,02719782 ! pseudouridine synthase activity GO:0009982 12 12 0,000 0,0133827 0,02718268 ! oocyte differentiation GO:0009994 13 12 0,000 0,0133827 0,02716755 ! oxygen transport GO:0015671 13 12 0,000 0,0133827 0,02715244 GO:0005344|oxygen transporter activity, ! thymus development GO:0048538 13 12 0,000 0,0133827 0,02713735 ! cholesterol efflux GO:0033344 13 12 0,000 0,0133827 0,02712227 ! digestive tract morphogenesis GO:0048546 14 12 0,000 0,0133827 0,02710721 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! racemase and epimerase activity GO:0016854 13 12 0,000 0,0133827 0,02709217 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 14 12 0,000 0,0133827 0,02707714 ! tropomyosin binding GO:0005523 12 12 0,000 0,0133827 0,02706213 ! blastocyst formation GO:0001825 13 12 0,000 0,0133827 0,02704714 ! regulation of telomere maintenance GO:0032204 16 12 0,000 0,0133827 0,02703217 ! internal side of plasma membrane GO:0009898 16 12 0,000 0,0133827 0,02701721 ! mannose binding GO:0005537 13 12 0,000 0,0133827 0,02700226 ! phosphoprotein binding GO:0051219 14 12 0,000 0,0133827 0,02698734 ! defense response to fungus GO:0050832 12 12 0,000 0,0133827 0,02697243 ! embryonic placenta development GO:0001892 16 12 0,000 0,0133827 0,02695753 ! regulation of steroid biosynthetic process GO:0050810 12 12 0,000 0,0133827 0,02694266 ! cell wall macromolecule metabolic process GO:0044036 15 12 0,000 0,0133827 0,02692779 ! acyl-CoA binding GO:0000062 12 12 0,000 0,0133827 0,02691295 ! cortical cytoskeleton organization GO:0030865 13 12 0,000 0,0133827 0,02689812 ! regulation of nitric-oxide synthase activity GO:0050999 12 12 0,000 0,0133827 0,02688331 ! copper ion transport GO:0006825 12 12 0,000 0,0133827 0,02686851 ! calcium ion transport into cytosol GO:0060402 19 12 0,000 0,0133827 0,02685374 ! inositol metabolic process GO:0006020 21 12 0,000 0,0133827 0,02683897 ! vesicle targeting, to, from or within Golgi GO:0048199 13 12 0,000 0,0133827 0,02682423 ! forelimb morphogenesis GO:0035136 15 12 0,000 0,0133827 0,0268095 ! protein complex disassembly GO:0043241 15 12 0,000 0,0133827 0,02679478 GO:0043624|cellular protein complex disassembly, ! ion channel inhibitor activity GO:0008200 15 12 0,000 0,0133827 0,02678008 GO:0016248|channel inhibitor activity, ! low-density lipoprotein particle GO:0034362 13 12 0,000 0,0133827 0,0267654 ! lipoprotein particle clearance GO:0034381 14 12 0,000 0,0133827 0,02675073 ! receptor signaling protein tyrosine kinase activity GO:0004716 14 12 0,000 0,0133827 0,02673608 ! endothelial cell differentiation GO:0045446 15 12 0,000 0,0133827 0,02672145 ! exosome (RNase complex) GO:0000178 13 12 0,000 0,0133827 0,02670683 ! DNA N-glycosylase activity GO:0019104 12 12 0,000 0,0133827 0,02669223 ! endoderm development GO:0007492 13 12 0,000 0,0133827 0,02667765 ! positive regulation of Ras protein signal transduction GO:0046579 25 12 0,000 0,0133827 0,02666308 ! focal adhesion formation GO:0048041 16 12 0,000 0,0133827 0,02664852 ! T cell receptor complex GO:0042101 31 12 0,000 0,0133827 0,02663398 ! cellular carbohydrate catabolic process GO:0044275 25 12 0,000 0,0133827 0,02661946 ! dicarboxylic acid transmembrane transporter activity GO:0005310 14 12 0,000 0,0133827 0,02660495 ! CoA hydrolase activity GO:0016289 14 12 0,000 0,0133827 0,02659046 ! histone acetyltransferase complex GO:0000123 14 12 0,000 0,0133827 0,02657599 ! regulation of alpha-beta T cell differentiation GO:0046637 13 12 0,000 0,0133827 0,02656153 ! alpha-beta T cell activation GO:0046631 14 12 0,000 0,0133827 0,02654709 ! retinol binding GO:0019841 12 12 0,000 0,0133827 0,02653266 ! regulation of organ growth GO:0046620 12 12 0,000 0,0133827 0,02651825 ! regulation of natural killer cell mediated immunity GO:0002715 13 12 0,000 0,0133827 0,02650385 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! vasoconstriction GO:0042310 13 12 0,000 0,0133827 0,02648947 ! histone acetylation GO:0016573 13 12 0,000 0,0133827 0,0264751 ! ribosome binding GO:0043022 13 12 0,000 0,0133827 0,02646075 ! delayed rectifier potassium channel activity GO:0005251 14 12 0,000 0,0133827 0,02644642 ! organic cation transmembrane transporter activity GO:0015101 12 12 0,000 0,0133827 0,0264321 ! phosphate transmembrane transporter activity GO:0015114 14 12 0,000 0,0133827 0,0264178 ! tissue regeneration GO:0042246 12 12 0,000 0,0133827 0,02640351 ! sulfate transmembrane transporter activity GO:0015116 13 12 0,000 0,0133827 0,02638924 ! adenylyltransferase activity GO:0070566 13 12 0,000 0,0133827 0,02637498 ! germ cell nucleus GO:0043073 14 12 0,000 0,0133827 0,02636074 ! trans-Golgi network transport vesicle membrane GO:0012510 16 12 0,000 0,0133827 0,02634651 ! hexose transmembrane transporter activity GO:0015149 12 12 0,000 0,0133827 0,0263323 ! hexosaminidase activity GO:0015929 12 12 0,000 0,0133827 0,02631811 ! regulation of acute inflammatory response GO:0002673 12 12 0,000 0,0133827 0,02630393 ! activation of NF-kappaB-inducing kinase activity GO:0007250 14 12 0,000 0,0133827 0,02628976 ! transmembrane receptor protein serine/threonine kinase signaling protein activity GO:0005071 13 12 0,000 0,0133827 0,02627561 ! dopamine metabolic process GO:0042417 15 12 0,000 0,0133827 0,02626148 ! somatic diversification of immunoglobulins GO:0016445 12 12 0,000 0,0133827 0,02624736 ! phosphoinositide 3-kinase activity GO:0035004 14 12 0,000 0,0133827 0,02623326 ! insulin-like growth factor receptor binding GO:0005159 14 12 0,000 0,0133827 0,02621917 ! bacterial binding GO:0008367 14 12 0,000 0,0133827 0,02620509 ! steroid hydroxylase activity GO:0008395 12 12 0,000 0,0133827 0,02619104 ! cardiac cell differentiation GO:0035051 16 12 0,000 0,0133827 0,02617699 ! phosphoinositide 3-kinase complex GO:0005942 14 12 0,000 0,0133827 0,02616296 ! localization within membrane GO:0051668 13 12 0,000 0,0133827 0,02614895 ! microtubule-based flagellum GO:0009434 12 12 0,000 0,0133827 0,02613495 ! axoneme part GO:0044447 12 12 0,000 0,0133827 0,02612097 ! regulation of membrane protein ectodomain proteolysis GO:0051043 14 13 0,000 0,01449019 0,0282675 ! neuron maturation GO:0042551 14 13 0,000 0,01449019 0,02825239 ! positive regulation of small GTPase mediated signal transduction GO:0051057 26 13 0,000 0,01449019 0,0282373 ! negative regulation of bone remodeling GO:0046851 15 13 0,000 0,01449019 0,02822222 ! bone remodeling GO:0046849 14 13 0,000 0,01449019 0,02820716 ! nicotinic acetylcholine-gated receptor-channel complex GO:0005892 13 13 0,000 0,01449019 0,02819212 ! regulation of receptor-mediated endocytosis GO:0048259 15 13 0,000 0,01449019 0,02817709 ! patterning of blood vessels GO:0001569 15 13 0,000 0,01449019 0,02816208 ! palate development GO:0060021 15 13 0,000 0,01449019 0,02814708 ! induction of apoptosis via death domain receptors GO:0008625 16 13 0,000 0,01449019 0,0281321 ! arginine metabolic process GO:0006525 14 13 0,000 0,01449019 0,02811714 ! ER-Golgi intermediate compartment membrane GO:0033116 23 13 0,000 0,01449019 0,02810219 ! tyrosine metabolic process GO:0006570 15 13 0,000 0,01449019 0,02808726 ! response to retinoic acid GO:0032526 17 13 0,000 0,01449019 0,02807234 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 15 13 0,000 0,01449019 0,02805744 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! lipase inhibitor activity GO:0055102 14 13 0,000 0,01449019 0,02804256 ! negative regulation of endothelial cell migration GO:0010596 15 13 0,000 0,01449019 0,02802769 ! fear response GO:0042596 15 13 0,000 0,01449019 0,02801284 ! epithelial cell development GO:0002064 22 13 0,000 0,01449019 0,027998 ! branching involved in ureteric bud morphogenesis GO:0001658 14 13 0,000 0,01449019 0,02798318 GO:0060675|ureteric bud morphogenesis, ! positive regulation of fatty acid metabolic process GO:0045923 14 13 0,000 0,01449019 0,02796837 ! protein kinase activator activity GO:0030295 17 13 0,000 0,01449019 0,02795358 ! heparan sulfate proteoglycan metabolic process GO:0030201 13 13 0,000 0,01449019 0,02793881 ! positive regulation of foam cell differentiation GO:0010744 16 13 0,000 0,01449019 0,02792405 ! protein targeting to peroxisome GO:0006625 13 13 0,000 0,01449019 0,0279093 ! NLS-bearing substrate import into nucleus GO:0006607 15 13 0,000 0,01449019 0,02789458 ! cranial nerve development GO:0021545 15 13 0,000 0,01449019 0,02787986 ! eye photoreceptor cell differentiation GO:0001754 17 13 0,000 0,01449019 0,02786517 GO:0042462|eye photoreceptor cell development, ! DNA-directed RNA polymerase II, core complex GO:0005665 14 13 0,000 0,01449019 0,02785049 ! cerebellum morphogenesis GO:0021587 15 13 0,000 0,01449019 0,02783582 ! MHC class I receptor activity GO:0032393 20 13 0,000 0,01449019 0,02782117 ! exoribonuclease activity GO:0004532 13 13 0,000 0,01449019 0,02780653 GO:0016896|exoribonuclease activity, producing 5'-phosphomonoesters, ! intrinsic to peroxisomal membrane GO:0031231 13 13 0,000 0,01449019 0,02779192 ! COPI-coated vesicle GO:0030137 15 13 0,000 0,01449019 0,02777731 ! cofactor transporter activity GO:0051184 15 13 0,000 0,01449019 0,02776272 ! NADP metabolic process GO:0006739 15 13 0,000 0,01449019 0,02774815 ! negative regulation of macrophage differentiation GO:0045650 16 13 0,000 0,01449019 0,02773359 ! regulation of osteoclast differentiation GO:0045670 15 13 0,000 0,01449019 0,02771905 ! aromatic amino acid family catabolic process GO:0009074 13 13 0,000 0,01449019 0,02770452 ! eukaryotic cell surface binding GO:0043499 15 13 0,000 0,01449019 0,02769001 ! proximal/distal pattern formation GO:0009954 15 13 0,000 0,01449019 0,02767551 ! positive regulation of JNK cascade GO:0046330 17 13 0,000 0,01449019 0,02766103 ! positive regulation of glucose import GO:0046326 16 13 0,000 0,01449019 0,02764656 GO:0010828|positive regulation of glucose transport, ! epithelial to mesenchymal transition GO:0001837 13 13 0,000 0,01449019 0,02763211 ! defense response to Gram-positive bacterium GO:0050830 14 13 0,000 0,01449019 0,02761767 ! mismatched DNA binding GO:0030983 13 13 0,000 0,01449019 0,02760325 ! positive regulation of synaptic transmission GO:0050806 15 13 0,000 0,01449019 0,02758884 ! neuron fate specification GO:0048665 25 13 0,000 0,01449019 0,02757445 ! N-terminal protein amino acid modification GO:0031365 14 13 0,000 0,01449019 0,02756007 ! dicarboxylic acid transport GO:0006835 15 13 0,000 0,01449019 0,02754571 ! water transport GO:0006833 18 13 0,000 0,01449019 0,02753137 GO:0042044|fluid transport, ! replisome GO:0030894 24 13 0,000 0,01449019 0,02751703 GO:0043601|nuclear replisome, ! cytosolic calcium ion transport GO:0060401 20 13 0,000 0,01449019 0,02750272 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,01449019 0,02748842 ! inorganic anion exchanger activity GO:0005452 13 13 0,000 0,01449019 0,02747413 ! negative regulation of ion transport GO:0043271 15 13 0,000 0,01449019 0,02745986 ! retinoic acid receptor binding GO:0042974 14 13 0,000 0,01449019 0,0274456 ! blood vessel remodeling GO:0001974 16 13 0,000 0,01449019 0,02743136 ! myoblast differentiation GO:0045445 15 13 0,000 0,01449019 0,02741713 ! ventral spinal cord development GO:0021517 16 13 0,000 0,01449019 0,02740291 ! prenyltransferase activity GO:0004659 15 13 0,000 0,01449019 0,02738872 ! activation of MAPKK activity GO:0000186 13 13 0,000 0,01449019 0,02737453 ! protein histidine kinase activity GO:0004673 15 13 0,000 0,01449019 0,02736036 GO:0000155|two-component sensor activity, ! cullin-RING ubiquitin ligase complex GO:0031461 13 13 0,000 0,01449019 0,02734621 ! regulation of skeletal muscle fiber development GO:0048742 16 13 0,000 0,01449019 0,02733207 ! acyl-CoA dehydrogenase activity GO:0003995 14 13 0,000 0,01449019 0,02731794 ! exocrine system development GO:0035272 14 13 0,000 0,01449019 0,02730383 ! membrane protein proteolysis GO:0033619 14 13 0,000 0,01449019 0,02728974 GO:0006509|membrane protein ectodomain proteolysis, ! organic alcohol transport GO:0015850 17 13 0,000 0,01449019 0,02727566 ! calcium ion transmembrane transporter activity GO:0015085 15 13 0,000 0,01449019 0,02726159 ! L-glutamate transport GO:0015813 14 13 0,000 0,01449019 0,02724754 GO:0015800|acidic amino acid transport, ! embryo implantation GO:0007566 17 13 0,000 0,01449019 0,0272335 ! G1/S transition checkpoint GO:0031575 14 13 0,000 0,01449019 0,02721948 ! immunoglobulin binding GO:0019865 14 13 0,000 0,01449019 0,02720547 ! negative regulation of protein import into nucleus GO:0042308 13 13 0,000 0,01449019 0,02719147 ! regulation of T cell mediated immunity GO:0002709 17 13 0,000 0,01449019 0,02717749 ! DNA unwinding during replication GO:0006268 14 13 0,000 0,01449019 0,02716353 ! genitalia development GO:0048806 18 13 0,000 0,01449019 0,02714957 ! regulation of interleukin-8 production GO:0032677 15 13 0,000 0,01449019 0,02713564 ! regulation of interleukin-12 production GO:0032655 13 13 0,000 0,01449019 0,02712171 ! MHC class I protein binding GO:0042288 23 13 0,000 0,01449019 0,02710781 ! histone deacetylation GO:0016575 14 13 0,000 0,01449019 0,02709391 ! calcium channel regulator activity GO:0005246 16 13 0,000 0,01449019 0,02708003 ! DNA methylation GO:0006306 15 13 0,000 0,01449019 0,02706617 GO:0006305|DNA alkylation, ! mRNA splice site selection GO:0006376 17 13 0,000 0,01449019 0,02705231 ! chromatin silencing GO:0006342 13 13 0,000 0,01449019 0,02703848 ! serotonin receptor activity GO:0004993 16 13 0,000 0,01449019 0,02702465 ! monosaccharide transmembrane transporter activity GO:0015145 13 13 0,000 0,01449019 0,02701084 ! T cell homeostasis GO:0043029 14 13 0,000 0,01449019 0,02699705 ! peptide biosynthetic process GO:0043043 14 13 0,000 0,01449019 0,02698327 ! diacylglycerol kinase activity GO:0004143 15 13 0,000 0,01449019 0,0269695 ! response to gamma radiation GO:0010332 14 13 0,000 0,01449019 0,02695575 ! synaptic transmission, cholinergic GO:0007271 14 13 0,000 0,01449019 0,02694201 ! retinoic acid receptor activity GO:0003708 15 13 0,000 0,01449019 0,02692828 ! purine base metabolic process GO:0006144 15 13 0,000 0,01449019 0,02691457 ! cAMP binding GO:0030552 15 13 0,000 0,01449019 0,02690088 ! biogenic amine catabolic process GO:0042402 14 13 0,000 0,01449019 0,02688719 ! negative regulation of BMP signaling pathway GO:0030514 14 13 0,000 0,01449019 0,02687352 ! regulation of axon extension GO:0030516 16 13 0,000 0,01449019 0,02685987 ! drug transporter activity GO:0015238 14 13 0,000 0,01449019 0,02684623 ! regulation of NF-kappaB import into nucleus GO:0042345 14 13 0,000 0,01449019 0,0268326 ! calcium-activated potassium channel activity GO:0015269 15 13 0,000 0,01449019 0,02681899 ! response to cold GO:0009409 13 13 0,000 0,01449019 0,02680539 ! cadherin binding GO:0045296 16 13 0,000 0,01449019 0,0267918 ! nucleolar part GO:0044452 13 13 0,000 0,01449019 0,02677823 ! tRNA modification GO:0006400 14 14 0,000 0,0155965 0,02880812 ! cis-Golgi network GO:0005801 16 14 0,000 0,0155965 0,02879354 ! negative regulation of hormone secretion GO:0046888 14 14 0,000 0,0155965 0,02877898 ! 'de novo' protein folding GO:0006458 14 14 0,000 0,0155965 0,02876443 ! organellar large ribosomal subunit GO:0000315 15 14 0,000 0,0155965 0,02874989 GO:0005762|mitochondrial large ribosomal subunit, ! phosphoinositide phosphorylation GO:0046854 18 14 0,000 0,0155965 0,02873537 ! peroxisomal transport GO:0043574 14 14 0,000 0,0155965 0,02872087 ! cardiac muscle contraction GO:0060048 15 14 0,000 0,0155965 0,02870637 ! dopamine receptor signaling pathway GO:0007212 19 14 0,000 0,0155965 0,0286919 ! mechanoreceptor differentiation GO:0042490 16 14 0,000 0,0155965 0,02867744 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 18 14 0,000 0,0155965 0,02866299 ! pseudouridine synthesis GO:0001522 14 14 0,000 0,0155965 0,02864856 ! caspase activator activity GO:0008656 16 14 0,000 0,0155965 0,02863414 ! MHC class II protein complex GO:0042613 19 14 0,000 0,0155965 0,02861974 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,0155965 0,02860535 ! cAMP-dependent protein kinase regulator activity GO:0008603 17 14 0,000 0,0155965 0,02859097 ! cation:cation antiporter activity GO:0015491 14 14 0,000 0,0155965 0,02857661 ! glycoprotein catabolic process GO:0006516 16 14 0,000 0,0155965 0,02856227 ! protein polyubiquitination GO:0000209 15 14 0,000 0,0155965 0,02854793 ! oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor GO:0016641 34 14 0,000 0,0155965 0,02853362 ! negative regulation of microtubule depolymerization GO:0007026 16 14 0,000 0,0155965 0,02851932 GO:0031114|regulation of microtubule depolymerization, ! cell-cell junction assembly GO:0007043 15 14 0,000 0,0155965 0,02850503 ! response to vitamin A GO:0033189 18 14 0,000 0,0155965 0,02849075 ! actin filament bundle formation GO:0051017 16 14 0,000 0,0155965 0,02847649 ! regulation of lipoprotein lipase activity GO:0051004 15 14 0,000 0,0155965 0,02846225 ! plasma membrane fusion GO:0045026 15 14 0,000 0,0155965 0,02844802 ! purine nucleoside monophosphate metabolic process GO:0009126 15 14 0,000 0,0155965 0,0284338 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of viral reproduction GO:0050792 16 14 0,000 0,0155965 0,0284196 ! protein export from nucleus GO:0006611 14 14 0,000 0,0155965 0,02840541 ! presynaptic membrane GO:0042734 14 14 0,000 0,0155965 0,02839123 ! negative regulation of immune response GO:0050777 21 14 0,000 0,0155965 0,02837707 ! gastrulation with mouth forming second GO:0001702 15 14 0,000 0,0155965 0,02836293 ! neural crest cell migration GO:0001755 15 14 0,000 0,0155965 0,0283488 ! anaphase-promoting complex GO:0005680 17 14 0,000 0,0155965 0,02833468 ! positive regulation of oxidoreductase activity GO:0051353 14 14 0,000 0,0155965 0,02832057 ! negative regulation of protein secretion GO:0050709 17 14 0,000 0,0155965 0,02830648 ! cofactor transport GO:0051181 16 14 0,000 0,0155965 0,02829241 ! C21-steroid hormone biosynthetic process GO:0006700 14 14 0,000 0,0155965 0,02827835 ! protein-chromophore linkage GO:0018298 16 14 0,000 0,0155965 0,0282643 ! cobalt ion binding GO:0050897 14 14 0,000 0,0155965 0,02825027 ! glutamine family amino acid biosynthetic process GO:0009084 16 14 0,000 0,0155965 0,02823625 ! positive regulation of transmission of nerve impulse GO:0051971 16 14 0,000 0,0155965 0,02822224 ! aspartate family amino acid biosynthetic process GO:0009067 17 14 0,000 0,0155965 0,02820825 ! gas transport GO:0015669 15 14 0,000 0,0155965 0,02819427 ! pyridine nucleotide biosynthetic process GO:0019363 15 14 0,000 0,0155965 0,0281803 ! heme biosynthetic process GO:0006783 14 14 0,000 0,0155965 0,02816635 ! cerebellar cortex development GO:0021695 16 14 0,000 0,0155965 0,02815242 ! insulin secretion GO:0030073 17 14 0,000 0,0155965 0,02813849 ! tRNA binding GO:0000049 16 14 0,000 0,0155965 0,02812458 ! positive regulation of cell killing GO:0031343 16 14 0,000 0,0155965 0,02811069 ! positive regulation of protein complex assembly GO:0031334 14 14 0,000 0,0155965 0,02809681 ! G1 phase of mitotic cell cycle GO:0000080 15 14 0,000 0,0155965 0,02808294 ! phosphatidylinositol metabolic process GO:0046488 15 14 0,000 0,0155965 0,02806908 ! regulation of neuronal synaptic plasticity GO:0048168 24 14 0,000 0,0155965 0,02805524 ! cytokine biosynthetic process GO:0042089 14 14 0,000 0,0155965 0,02804142 ! mannosyltransferase activity GO:0000030 14 14 0,000 0,0155965 0,0280276 ! isoprenoid biosynthetic process GO:0008299 17 14 0,000 0,0155965 0,0280138 ! C-C chemokine binding GO:0019957 15 14 0,000 0,0155965 0,02800002 GO:0016493|C-C chemokine receptor activity, ! cardiac muscle tissue development GO:0048738 16 14 0,000 0,0155965 0,02798624 ! complement activation, alternative pathway GO:0006957 14 14 0,000 0,0155965 0,02797248 ! response to osmotic stress GO:0006970 17 14 0,000 0,0155965 0,02795874 ! fructose metabolic process GO:0006000 15 14 0,000 0,0155965 0,02794501 ! telomeric DNA binding GO:0042162 17 14 0,000 0,0155965 0,02793129 ! monoamine transport GO:0015844 15 14 0,000 0,0155965 0,02791758 ! regulation of pathway-restricted SMAD protein phosphorylation GO:0060393 14 14 0,000 0,0155965 0,02790389 ! nucleoside kinase activity GO:0019206 17 14 0,000 0,0155965 0,02789021 ! dendritic spine GO:0043197 15 14 0,000 0,0155965 0,02787655 ! stem cell development GO:0048864 14 14 0,000 0,0155965 0,0278629 GO:0019827|stem cell maintenance, ! regulation of alpha-beta T cell activation GO:0046634 15 14 0,000 0,0155965 0,02784926 ! regulation of insulin receptor signaling pathway GO:0046626 17 14 0,000 0,0155965 0,02783563 ! regulation of cytokine production during immune response GO:0002718 15 14 0,000 0,0155965 0,02782202 ! positive regulation of protein import into nucleus GO:0042307 16 14 0,000 0,0155965 0,02780842 ! regulation of cellular pH GO:0030641 14 14 0,000 0,0155965 0,02779484 ! regulation of monooxygenase activity GO:0032768 14 14 0,000 0,0155965 0,02778127 ! intracellular ligand-gated ion channel activity GO:0005217 14 14 0,000 0,0155965 0,02776771 ! sarcoplasmic reticulum membrane GO:0033017 16 14 0,000 0,0155965 0,02775416 ! detection of biotic stimulus GO:0009595 16 14 0,000 0,0155965 0,02774063 ! nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity GO:0015932 16 14 0,000 0,0155965 0,02772711 ! mannosidase activity GO:0015923 19 14 0,000 0,0155965 0,02771361 ! calcium-dependent cysteine-type endopeptidase activity GO:0004198 17 14 0,000 0,0155965 0,02770011 ! negative regulation of tissue remodeling GO:0034104 16 14 0,000 0,0155965 0,02768663 ! positive regulation of bone mineralization GO:0030501 14 14 0,000 0,0155965 0,02767317 ! neuromuscular synaptic transmission GO:0007274 15 14 0,000 0,0155965 0,02765972 ! regulation of immunoglobulin production GO:0002637 15 14 0,000 0,0155965 0,02764628 ! cAMP biosynthetic process GO:0006171 14 14 0,000 0,0155965 0,02763285 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 16 14 0,000 0,0155965 0,02761943 ! fucosyltransferase activity GO:0008417 16 14 0,000 0,0155965 0,02760603 ! sperm-egg recognition GO:0035036 17 14 0,000 0,0155965 0,02759265 GO:0007339|binding of sperm to zona pellucida, ! defense response to virus GO:0051607 21 14 0,000 0,0155965 0,02757927 ! SWI/SNF-type complex GO:0070603 16 14 0,000 0,0155965 0,02756591 GO:0016514|SWI/SNF complex, ! aldo-keto reductase activity GO:0004033 15 14 0,000 0,0155965 0,02755256 ! positive regulation of translation GO:0045727 17 15 0,000 0,01670163 0,02949058 ! nuclear replication fork GO:0043596 26 15 0,000 0,01670163 0,02947631 ! transferase activity, transferring amino-acyl groups GO:0016755 15 15 0,000 0,01670163 0,02946206 ! 2'-deoxyribonucleotide metabolic process GO:0009394 16 15 0,000 0,01670163 0,02944782 GO:0019692|deoxyribose phosphate metabolic process, ! phospholipid catabolic process GO:0009395 26 15 0,000 0,01670163 0,02943359 ! endothelial cell migration GO:0043542 16 15 0,000 0,01670163 0,02941938 ! lipid phosphorylation GO:0046834 19 15 0,000 0,01670163 0,02940518 ! negative regulation of nucleocytoplasmic transport GO:0046823 15 15 0,000 0,01670163 0,02939099 ! response to vitamin GO:0033273 19 15 0,000 0,01670163 0,02937682 ! gene silencing by RNA GO:0031047 17 15 0,000 0,01670163 0,02936267 ! striated muscle thick filament GO:0005863 16 15 0,000 0,01670163 0,02934852 GO:0032982|myosin filament, ! cellular response to hydrogen peroxide GO:0070301 15 15 0,000 0,01670163 0,02933439 GO:0042744|hydrogen peroxide catabolic process, ! endocrine pancreas development GO:0031018 16 15 0,000 0,01670163 0,02932028 ! regulation of interleukin-2 biosynthetic process GO:0045076 15 15 0,000 0,01670163 0,02930617 ! glutamate metabolic process GO:0006536 17 15 0,000 0,01670163 0,02929208 ! pituitary gland development GO:0021983 16 15 0,000 0,01670163 0,02927801 ! cholesterol binding GO:0015485 15 15 0,000 0,01670163 0,02926394 ! NAD metabolic process GO:0019674 17 15 0,000 0,01670163 0,0292499 ! protease binding GO:0002020 20 15 0,000 0,01670163 0,02923586 ! regulation of heart rate GO:0002027 20 15 0,000 0,01670163 0,02922184 ! Golgi cisterna GO:0031985 17 15 0,000 0,01670163 0,02920783 ! regulation of exocytosis GO:0017157 16 15 0,000 0,01670163 0,02919383 ! positive regulation of axonogenesis GO:0050772 16 15 0,000 0,01670163 0,02917985 ! embryonic digit morphogenesis GO:0042733 17 15 0,000 0,01670163 0,02916588 ! positive regulation of biomineral formation GO:0070169 15 15 0,000 0,01670163 0,02915193 ! prostaglandin metabolic process GO:0006693 15 15 0,000 0,01670163 0,02913799 GO:0006692|prostanoid metabolic process, ! postsynaptic density GO:0014069 20 15 0,000 0,01670163 0,02912406 ! neuron recognition GO:0008038 18 15 0,000 0,01670163 0,02911014 ! regulation of Rho GTPase activity GO:0032319 18 15 0,000 0,01670163 0,02909624 ! hindbrain morphogenesis GO:0021575 18 15 0,000 0,01670163 0,02908235 ! filopodium GO:0030175 17 15 0,000 0,01670163 0,02906848 ! negative regulation of blood coagulation GO:0030195 18 15 0,000 0,01670163 0,02905462 ! folic acid and derivative metabolic process GO:0006760 15 15 0,000 0,01670163 0,02904077 ! positive regulation of neuron differentiation GO:0045666 27 15 0,000 0,01670163 0,02902693 ! peptide hormone binding GO:0017046 16 15 0,000 0,01670163 0,02901311 ! regulation of ATPase activity GO:0043462 17 15 0,000 0,01670163 0,0289993 ! endoribonuclease activity, producing 3'-phosphomonoesters GO:0016892 16 15 0,000 0,01670163 0,0289855 ! regulation of leukocyte mediated cytotoxicity GO:0001910 21 15 0,000 0,01670163 0,02897172 ! acid-thiol ligase activity GO:0016878 16 15 0,000 0,01670163 0,02895795 ! aromatic compound biosynthetic process GO:0019438 25 15 0,000 0,01670163 0,0289442 ! positive regulation of calcium ion transport GO:0051928 20 15 0,000 0,01670163 0,02893045 ! dystrophin-associated glycoprotein complex GO:0016010 17 15 0,000 0,01670163 0,02891672 ! RNA 3'-end processing GO:0031123 16 15 0,000 0,01670163 0,028903 ! developmental induction GO:0031128 17 15 0,000 0,01670163 0,0288893 GO:0045168|cell-cell signaling involved in cell fate specification, ! negative regulation of microtubule polymerization or depolymerization GO:0031111 17 15 0,000 0,01670163 0,02887561 ! protein import into nucleus, docking GO:0000059 15 15 0,000 0,01670163 0,02886193 ! regulation of skeletal muscle tissue development GO:0048641 18 15 0,000 0,01670163 0,02884826 ! lactation GO:0007595 17 15 0,000 0,01670163 0,02883461 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 16 15 0,000 0,01670163 0,02882097 GO:0016444|somatic cell DNA recombination, ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,01670163 0,02880734 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,01670163 0,02879373 ! double-strand break repair via homologous recombination GO:0000724 36 15 0,000 0,01670163 0,02878013 GO:0000725|recombinational repair, ! phosphatidylcholine metabolic process GO:0046470 16 15 0,000 0,01670163 0,02876654 ! regulation of cell-cell adhesion GO:0022407 18 15 0,000 0,01670163 0,02875296 ! sulfate transport GO:0008272 16 15 0,000 0,01670163 0,0287394 ! hindlimb morphogenesis GO:0035137 17 15 0,000 0,01670163 0,02872585 ! bile acid metabolic process GO:0008206 17 15 0,000 0,01670163 0,02871231 ! very-low-density lipoprotein particle GO:0034361 16 15 0,000 0,01670163 0,02869879 GO:0034385|triglyceride-rich lipoprotein particle, ! adult walking behavior GO:0007628 19 15 0,000 0,01670163 0,02868528 ! 2 iron, 2 sulfur cluster binding GO:0051537 16 15 0,000 0,01670163 0,02867178 ! heart looping GO:0001947 18 15 0,000 0,01670163 0,02865829 ! protein kinase C activity GO:0004697 17 15 0,000 0,01670163 0,02864482 ! oligodendrocyte differentiation GO:0048709 15 15 0,000 0,01670163 0,02863136 ! regulation of striated muscle contraction GO:0006942 18 15 0,000 0,01670163 0,02861791 ! pigmentation during development GO:0048066 17 15 0,000 0,01670163 0,02860447 ! cytokine metabolic process GO:0042107 15 15 0,000 0,01670163 0,02859105 ! vesicle coating GO:0006901 17 15 0,000 0,01670163 0,02857764 ! disulfide oxidoreductase activity GO:0015036 16 15 0,000 0,01670163 0,02856424 ! neutral amino acid transport GO:0015804 18 15 0,000 0,01670163 0,02855086 ! L-amino acid transport GO:0015807 16 15 0,000 0,01670163 0,02853749 ! microfilament motor activity GO:0000146 15 15 0,000 0,01670163 0,02852413 ! carbonate dehydratase activity GO:0004089 18 15 0,000 0,01670163 0,02851078 ! regulation of vasodilation GO:0042312 25 15 0,000 0,01670163 0,02849744 ! DNA replication initiation GO:0006270 15 15 0,000 0,01670163 0,02848412 ! taste receptor activity GO:0008527 15 15 0,000 0,01670163 0,02847081 ! cellular pigmentation GO:0033059 16 15 0,000 0,01670163 0,02845751 ! voltage-gated chloride channel activity GO:0005247 18 15 0,000 0,01670163 0,02844423 ! voltage-gated sodium channel activity GO:0005248 18 15 0,000 0,01670163 0,02843095 ! long-chain fatty acid transport GO:0015909 17 15 0,000 0,01670163 0,02841769 ! positive regulation of neurological system process GO:0031646 18 15 0,000 0,01670163 0,02840444 ! nerve-nerve synaptic transmission GO:0007270 17 15 0,000 0,01670163 0,02839121 ! ARF guanyl-nucleotide exchange factor activity GO:0005086 17 15 0,000 0,01670163 0,02837798 ! ion gated channel activity GO:0022839 17 15 0,000 0,01670163 0,02836477 ! heterogeneous nuclear ribonucleoprotein complex GO:0030530 15 15 0,000 0,01670163 0,02835157 ! receptor activator activity GO:0030546 17 15 0,000 0,01670163 0,02833839 ! protein transmembrane transporter activity GO:0008320 16 15 0,000 0,01670163 0,02832521 ! negative regulation of mast cell proliferation GO:0070667 16 15 0,000 0,01670163 0,02831205 GO:0042130|negative regulation of T cell proliferation, ! acylglycerol O-acyltransferase activity GO:0016411 16 15 0,000 0,01670163 0,0282989 ! triacylglycerol lipase activity GO:0004806 16 15 0,000 0,01670163 0,02828576 ! peptide hormone processing GO:0016486 19 15 0,000 0,01670163 0,02827264 ! phospholipid-translocating ATPase activity GO:0004012 16 15 0,000 0,01670163 0,02825952 GO:0015247|aminophospholipid transporter activity, ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 19 16 0,000 0,01780557 0,03011345 ! positive regulation of anti-apoptosis GO:0045768 16 16 0,000 0,01780557 0,0300995 ! phosphotransferase activity, nitrogenous group as acceptor GO:0016775 18 16 0,000 0,01780557 0,03008556 ! heterophilic cell adhesion GO:0007157 17 16 0,000 0,01780557 0,03007163 ! gamma-aminobutyric acid signaling pathway GO:0007214 17 16 0,000 0,01780557 0,03005771 ! kinesin complex GO:0005871 16 16 0,000 0,01780557 0,03004381 ! photoreceptor cell development GO:0042461 22 16 0,000 0,01780557 0,03002992 GO:0046530|photoreceptor cell differentiation, ! negative regulation of gene expression, epigenetic GO:0045814 16 16 0,000 0,01780557 0,03001604 ! mitotic chromosome condensation GO:0007076 17 16 0,000 0,01780557 0,03000218 ! centrosome cycle GO:0007098 26 16 0,000 0,01780557 0,02998833 ! negative regulation of epithelial cell proliferation GO:0050680 18 16 0,000 0,01780557 0,02997449 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 16 0,000 0,01780557 0,02996066 ! DNA duplex unwinding GO:0032508 17 16 0,000 0,01780557 0,02994685 GO:0032392|DNA geometric change, ! cerebral cortex development GO:0021987 16 16 0,000 0,01780557 0,02993305 ! lysosomal transport GO:0007041 16 16 0,000 0,01780557 0,02991926 ! transforming growth factor beta receptor activity GO:0005024 18 16 0,000 0,01780557 0,02990549 GO:0004675|transmembrane receptor protein serine/threonine kinase activity, ! rough endoplasmic reticulum GO:0005791 16 16 0,000 0,01780557 0,02989172 ! mitochondrial proton-transporting ATP synthase complex GO:0005753 16 16 0,000 0,01780557 0,02987798 ! small nucleolar ribonucleoprotein complex GO:0005732 16 16 0,000 0,01780557 0,02986424 ! G1 phase GO:0051318 17 16 0,000 0,01780557 0,02985051 ! receptor signaling complex scaffold activity GO:0030159 19 16 0,000 0,01780557 0,0298368 ! negative regulation of inflammatory response GO:0050728 17 16 0,000 0,01780557 0,0298231 ! clathrin vesicle coat GO:0030125 20 16 0,000 0,01780557 0,02980942 ! endodeoxyribonuclease activity GO:0004520 43 16 0,000 0,01780557 0,02979574 ! sphingolipid catabolic process GO:0030149 18 16 0,000 0,01780557 0,02978208 GO:0046466|membrane lipid catabolic process, ! natural killer cell activation GO:0030101 17 16 0,000 0,01780557 0,02976843 ! steroid catabolic process GO:0006706 18 16 0,000 0,01780557 0,0297548 ! branched chain family amino acid metabolic process GO:0009081 18 16 0,000 0,01780557 0,02974117 ! cell-cell recognition GO:0009988 19 16 0,000 0,01780557 0,02972756 ! somatic diversification of immune receptors GO:0002200 17 16 0,000 0,01780557 0,02971396 ! spleen development GO:0048536 19 16 0,000 0,01780557 0,02970037 ! lymphocyte homeostasis GO:0002260 17 16 0,000 0,01780557 0,0296868 ! regulation of fatty acid oxidation GO:0046320 19 16 0,000 0,01780557 0,02967324 ! neural tube closure GO:0001843 19 16 0,000 0,01780557 0,02965969 GO:0060606|tube closure, ! antigen receptor-mediated signaling pathway GO:0050851 22 16 0,000 0,01780557 0,02964615 ! regulation of protein ubiquitination GO:0031396 27 16 0,000 0,01780557 0,02963263 ! regulation of glucose metabolic process GO:0010906 18 16 0,000 0,01780557 0,02961911 ! regulation of lipid catabolic process GO:0050994 18 16 0,000 0,01780557 0,02960561 ! viral genome replication GO:0019079 16 16 0,000 0,01780557 0,02959213 ! regulation of neurotransmitter transport GO:0051588 19 16 0,000 0,01780557 0,02957865 ! memory GO:0007613 18 16 0,000 0,01780557 0,02956519 ! regulation of carbohydrate biosynthetic process GO:0043255 17 16 0,000 0,01780557 0,02955174 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,01780557 0,0295383 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 18 16 0,000 0,01780557 0,02952487 ! glycoprotein binding GO:0001948 19 16 0,000 0,01780557 0,02951146 ! negative regulation of endothelial cell proliferation GO:0001937 17 16 0,000 0,01780557 0,02949806 ! syntaxin binding GO:0019905 18 16 0,000 0,01780557 0,02948467 ! epidermis morphogenesis GO:0048730 18 16 0,000 0,01780557 0,02947129 ! fucose metabolic process GO:0006004 18 16 0,000 0,01780557 0,02945792 ! actin polymerization or depolymerization GO:0008154 18 16 0,000 0,01780557 0,02944457 ! membrane budding GO:0006900 18 16 0,000 0,01780557 0,02943123 ! preassembly of GPI anchor in ER membrane GO:0016254 18 16 0,000 0,01780557 0,0294179 ! intermediate filament cytoskeleton organization GO:0045104 16 16 0,000 0,01780557 0,02940458 ! behavioral interaction between organisms GO:0051705 19 16 0,000 0,01780557 0,02939128 ! nucleotide-excision repair, DNA gap filling GO:0006297 19 16 0,000 0,01780557 0,02937798 ! anchored to plasma membrane GO:0046658 20 16 0,000 0,01780557 0,0293647 ! calcium activated cation channel activity GO:0005227 18 16 0,000 0,01780557 0,02935143 ! apoptotic protease activator activity GO:0016505 18 16 0,000 0,01780557 0,02933817 ! sulfuric ester hydrolase activity GO:0008484 18 16 0,000 0,01780557 0,02932493 ! nicotinic acetylcholine-activated cation-selective channel activity GO:0004889 18 16 0,000 0,01780557 0,0293117 ! purine nucleotide catabolic process GO:0006195 16 16 0,000 0,01780557 0,02929847 ! RNA polymerase II transcription mediator activity GO:0016455 19 16 0,000 0,01780557 0,02928527 ! axoneme GO:0005930 16 16 0,000 0,01780557 0,02927207 ! negative regulation of homeostatic process GO:0032845 19 16 0,000 0,01780557 0,02925888 ! anion exchanger activity GO:0015380 17 17 0,000 0,01890833 0,031057 ! positive regulation of hormone secretion GO:0046887 19 17 0,000 0,01890833 0,03104302 ! phosphotransferase activity, for other substituted phosphate groups GO:0016780 17 17 0,000 0,01890833 0,03102906 ! transcription from RNA polymerase III promoter GO:0006383 18 17 0,000 0,01890833 0,03101511 ! glial cell development GO:0021782 17 17 0,000 0,01890833 0,03100117 ! limbic system development GO:0021761 18 17 0,000 0,01890833 0,03098724 ! protein phosphatase type 2A regulator activity GO:0008601 19 17 0,000 0,01890833 0,03097333 ! pyrimidine ribonucleotide metabolic process GO:0009218 20 17 0,000 0,01890833 0,03095942 ! ephrin receptor activity GO:0005003 21 17 0,000 0,01890833 0,03094554 ! acetylcholine receptor activity GO:0015464 18 17 0,000 0,01890833 0,03093166 ! glutamine metabolic process GO:0006541 26 17 0,000 0,01890833 0,03091779 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor GO:0016646 21 17 0,000 0,01890833 0,03090394 ! oxidoreductase activity, acting on the CH-NH2 group of donors GO:0016638 37 17 0,000 0,01890833 0,0308901 ! signal sequence binding GO:0005048 18 17 0,000 0,01890833 0,03087627 ! cell-substrate junction assembly GO:0007044 21 17 0,000 0,01890833 0,03086246 ! proton-transporting two-sector ATPase complex, catalytic domain GO:0033178 17 17 0,000 0,01890833 0,03084866 ! organelle subcompartment GO:0031984 19 17 0,000 0,01890833 0,03083487 ! regulation of dephosphorylation GO:0035303 20 17 0,000 0,01890833 0,03082109 ! regulation of vasoconstriction GO:0019229 21 17 0,000 0,01890833 0,03080732 ! membrane depolarization GO:0051899 19 17 0,000 0,01890833 0,03079357 ! oogenesis GO:0048477 20 17 0,000 0,01890833 0,03077983 ! nuclear outer membrane GO:0005640 21 17 0,000 0,01890833 0,0307661 ! regulation of immunoglobulin mediated immune response GO:0002889 18 17 0,000 0,01890833 0,03075238 GO:0002712|regulation of B cell mediated immunity, ! immunoglobulin production GO:0002377 21 17 0,000 0,01890833 0,03073868 GO:0002440|production of molecular mediator of immune response, ! positive regulation of cellular carbohydrate metabolic process GO:0010676 18 17 0,000 0,01890833 0,03072499 ! positive regulation of macrophage differentiation GO:0045651 21 17 0,000 0,01890833 0,03071131 ! organic cation transport GO:0015695 17 17 0,000 0,01890833 0,03069764 ! porphyrin biosynthetic process GO:0006779 17 17 0,000 0,01890833 0,03068398 GO:0033014|tetrapyrrole biosynthetic process, ! phosphatidylinositol binding GO:0005545 21 17 0,000 0,01890833 0,03067034 ! hyaluronic acid binding GO:0005540 19 17 0,000 0,01890833 0,03065671 ! regulation of mitotic metaphase/anaphase transition GO:0030071 18 17 0,000 0,01890833 0,03064309 ! negative regulation of coagulation GO:0050819 20 17 0,000 0,01890833 0,03062948 ! cellular monovalent inorganic cation homeostasis GO:0030004 18 17 0,000 0,01890833 0,03061589 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 23 17 0,000 0,01890833 0,03060231 ! positive regulation of smooth muscle cell proliferation GO:0048661 20 17 0,000 0,01890833 0,03058874 ! negative regulation of defense response GO:0031348 19 17 0,000 0,01890833 0,03057518 ! lipid localization GO:0010876 19 17 0,000 0,01890833 0,03056163 GO:0019915|lipid storage, ! tube lumen formation GO:0035148 20 17 0,000 0,01890833 0,03054809 ! negative regulation of cytokine biosynthetic process GO:0042036 18 17 0,000 0,01890833 0,03053457 ! regulation of systemic arterial blood pressure by hormone GO:0001990 17 17 0,000 0,01890833 0,03052106 GO:0050886|endocrine process, ! MAP kinase kinase kinase activity GO:0004709 19 17 0,000 0,01890833 0,03050756 ! negative regulation of protein amino acid phosphorylation GO:0001933 19 17 0,000 0,01890833 0,03049408 ! protein phosphatase type 2A complex GO:0000159 21 17 0,000 0,01890833 0,0304806 ! polypeptide N-acetylgalactosaminyltransferase activity GO:0004653 22 17 0,000 0,01890833 0,03046714 ! response to hexose stimulus GO:0009746 20 17 0,000 0,01890833 0,03045369 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! transmembrane receptor protein phosphatase activity GO:0019198 24 17 0,000 0,01890833 0,03044025 GO:0005001|transmembrane receptor protein tyrosine phosphatase activity, ! positive regulation of nitric oxide biosynthetic process GO:0045429 18 17 0,000 0,01890833 0,03042682 ! AMP binding GO:0016208 19 17 0,000 0,01890833 0,0304134 ! UDP-galactosyltransferase activity GO:0035250 19 17 0,000 0,01890833 0,0304 ! receptor metabolic process GO:0043112 20 17 0,000 0,01890833 0,03038661 ! neurotransmitter metabolic process GO:0042133 20 17 0,000 0,01890833 0,03037323 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 23 17 0,000 0,01890833 0,03035986 ! alcohol binding GO:0043178 20 17 0,000 0,01890833 0,0303465 ! T cell differentiation in the thymus GO:0033077 28 17 0,000 0,01890833 0,03033316 ! visual learning GO:0008542 31 17 0,000 0,01890833 0,03031982 ! structural constituent of eye lens GO:0005212 20 17 0,000 0,01890833 0,0303065 ! cellular amino acid derivative catabolic process GO:0042219 19 17 0,000 0,01890833 0,03029319 ! neutrophil chemotaxis GO:0030593 17 17 0,000 0,01890833 0,03027989 ! protein localization in mitochondrion GO:0070585 19 17 0,000 0,01890833 0,03026661 GO:0006626|protein targeting to mitochondrion, ! aspartic-type endopeptidase activity GO:0004190 18 17 0,000 0,01890833 0,03025333 GO:0070001|aspartic-type peptidase activity, ! neutral amino acid transmembrane transporter activity GO:0015175 19 17 0,000 0,01890833 0,03024007 ! proton-transporting ATP synthase complex GO:0045259 17 17 0,000 0,01890833 0,03022682 ! translation elongation factor activity GO:0003746 19 17 0,000 0,01890833 0,03021358 ! histone binding GO:0042393 26 17 0,000 0,01890833 0,03020035 ! cilium assembly GO:0042384 18 17 0,000 0,01890833 0,03018713 ! transforming growth factor beta receptor binding GO:0005160 19 17 0,000 0,01890833 0,03017393 ! positive regulation of homeostatic process GO:0032846 23 17 0,000 0,01890833 0,03016073 ! solute:hydrogen antiporter activity GO:0015299 18 17 0,000 0,01890833 0,03014755 ! protein secretion GO:0009306 19 18 0,000 0,02000992 0,03188999 ! positive regulation of ossification GO:0045778 19 18 0,000 0,02000992 0,03187606 ! positive regulation of angiogenesis GO:0045766 19 18 0,000 0,02000992 0,03186215 ! organellar small ribosomal subunit GO:0000314 18 18 0,000 0,02000992 0,03184824 GO:0005763|mitochondrial small ribosomal subunit, ! protein amino acid deacetylation GO:0006476 19 18 0,000 0,02000992 0,03183436 ! protein amino acid acetylation GO:0006473 21 18 0,000 0,02000992 0,03182048 ! positive regulation of nucleocytoplasmic transport GO:0046824 20 18 0,000 0,02000992 0,03180661 ! cAMP metabolic process GO:0046058 18 18 0,000 0,02000992 0,03179276 ! regulation of muscle cell differentiation GO:0051147 21 18 0,000 0,02000992 0,03177892 ! cornified envelope GO:0001533 22 18 0,000 0,02000992 0,03176509 ! retinoid metabolic process GO:0001523 19 18 0,000 0,02000992 0,03175127 GO:0016101|diterpenoid metabolic process, ! positive regulation of proteolysis GO:0045862 20 18 0,000 0,02000992 0,03173747 ! oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor GO:0016628 21 18 0,000 0,02000992 0,03172368 ! calcium-dependent protein binding GO:0048306 20 18 0,000 0,02000992 0,03170989 ! proton-transporting ATPase activity, rotational mechanism GO:0046961 18 18 0,000 0,02000992 0,03169613 ! proton-transporting V-type ATPase complex GO:0033176 18 18 0,000 0,02000992 0,03168237 ! pyrimidine ribonucleoside metabolic process GO:0046131 23 18 0,000 0,02000992 0,03166862 ! regulation of ion transmembrane transporter activity GO:0032412 21 18 0,000 0,02000992 0,03165489 ! positive regulation of carbohydrate metabolic process GO:0045913 19 18 0,000 0,02000992 0,03164117 ! primary neural tube formation GO:0014020 21 18 0,000 0,02000992 0,03162746 ! recycling endosome GO:0055037 22 18 0,000 0,02000992 0,03161376 ! kinase activator activity GO:0019209 22 18 0,000 0,02000992 0,03160008 ! positive regulation of T cell differentiation GO:0045582 28 18 0,000 0,02000992 0,0315864 ! cerebellum development GO:0021549 20 18 0,000 0,02000992 0,03157274 ! positive regulation of multicellular organism growth GO:0040018 19 18 0,000 0,02000992 0,03155909 ! somitogenesis GO:0001756 20 18 0,000 0,02000992 0,03154545 ! transcription factor TFIID complex GO:0005669 19 18 0,000 0,02000992 0,03153183 ! low-density lipoprotein binding GO:0030169 19 18 0,000 0,02000992 0,03151821 ! positive regulation of cytokine secretion GO:0050715 21 18 0,000 0,02000992 0,03150461 ! negative regulation of intracellular transport GO:0032387 20 18 0,000 0,02000992 0,03149102 ! glutamine family amino acid catabolic process GO:0009065 21 18 0,000 0,02000992 0,03147744 ! basal plasma membrane GO:0009925 21 18 0,000 0,02000992 0,03146387 GO:0045178|basal part of cell, ! vitamin D receptor binding GO:0042809 20 18 0,000 0,02000992 0,03145031 ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters GO:0016894 19 18 0,000 0,02000992 0,03143677 ! embryonic organ morphogenesis GO:0048562 22 18 0,000 0,02000992 0,03142324 ! negative regulation of translation GO:0017148 31 18 0,000 0,02000992 0,03140971 ! regulation of cell killing GO:0031341 24 18 0,000 0,02000992 0,0313962 ! positive regulation of cellular catabolic process GO:0031331 20 18 0,000 0,02000992 0,03138271 ! nuclear chromosome, telomeric region GO:0000784 30 18 0,000 0,02000992 0,03136922 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 19 18 0,000 0,02000992 0,03135575 ! intra-Golgi vesicle-mediated transport GO:0006891 20 18 0,000 0,02000992 0,03134228 ! protein complex scaffold GO:0032947 22 18 0,000 0,02000992 0,03132883 ! SNAP receptor activity GO:0005484 21 18 0,000 0,02000992 0,03131539 ! dendrite development GO:0016358 22 18 0,000 0,02000992 0,03130196 ! cell differentiation in spinal cord GO:0021515 21 18 0,000 0,02000992 0,03128855 ! inactivation of MAPK activity GO:0000188 20 18 0,000 0,02000992 0,03127514 ! calmodulin-dependent protein kinase activity GO:0004683 20 18 0,000 0,02000992 0,03126175 ! D-ribose metabolic process GO:0006014 19 18 0,000 0,02000992 0,03124836 ! nuclear ubiquitin ligase complex GO:0000152 31 18 0,000 0,02000992 0,03123499 ! glucuronosyltransferase activity GO:0015020 18 18 0,000 0,02000992 0,03122163 ! coreceptor activity GO:0015026 28 18 0,000 0,02000992 0,03120828 ! response to fungus GO:0009620 18 18 0,000 0,02000992 0,03119495 ! stem cell differentiation GO:0048863 18 18 0,000 0,02000992 0,03118162 ! intermediate filament-based process GO:0045103 18 18 0,000 0,02000992 0,03116831 ! heart process GO:0003015 19 18 0,000 0,02000992 0,031155 GO:0060047|heart contraction, ! mismatch repair GO:0006298 28 18 0,000 0,02000992 0,03114171 ! vasodilation GO:0042311 20 18 0,000 0,02000992 0,03112843 ! transport vesicle membrane GO:0030658 23 18 0,000 0,02000992 0,03111516 ! MHC protein binding GO:0042287 30 18 0,000 0,02000992 0,03110191 ! inward rectifier potassium channel activity GO:0005242 22 18 0,000 0,02000992 0,03108866 ! chloride transmembrane transporter activity GO:0015108 19 18 0,000 0,02000992 0,03107543 ! bicarbonate transmembrane transporter activity GO:0015106 18 18 0,000 0,02000992 0,0310622 ! ionotropic glutamate receptor activity GO:0004970 22 18 0,000 0,02000992 0,03104899 ! cell-cell adherens junction GO:0005913 20 18 0,000 0,02000992 0,03103579 ! negative regulation of leukocyte proliferation GO:0070664 20 18 0,000 0,02000992 0,0310226 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! ubiquitin-specific protease activity GO:0004843 19 18 0,000 0,02000992 0,03100942 ! ATP-dependent RNA helicase activity GO:0004004 28 18 0,000 0,02000992 0,03099625 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 24 19 0,000 0,02111032 0,03268695 ! pteridine and derivative metabolic process GO:0042558 29 19 0,000 0,02111032 0,03267308 ! proteasome core complex GO:0005839 20 19 0,000 0,02111032 0,03265923 ! hydrolase activity, hydrolyzing N-glycosyl compounds GO:0016799 22 19 0,000 0,02111032 0,03264538 ! anion:anion antiporter activity GO:0015301 19 19 0,000 0,02111032 0,03263155 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 24 19 0,000 0,02111032 0,03261773 ! regulation of transmembrane transporter activity GO:0022898 22 19 0,000 0,02111032 0,03260392 GO:0032409|regulation of transporter activity, ! activation of pro-apoptotic gene products GO:0008633 26 19 0,000 0,02111032 0,03259012 ! deoxyribonucleotide metabolic process GO:0009262 20 19 0,000 0,02111032 0,03257634 ! lysosome organization GO:0007040 20 19 0,000 0,02111032 0,03256256 ! cellular macromolecular complex disassembly GO:0034623 23 19 0,000 0,02111032 0,0325488 ! cellular response to unfolded protein GO:0034620 21 19 0,000 0,02111032 0,03253505 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron development GO:0021954 21 19 0,000 0,02111032 0,03252131 ! threonine-type endopeptidase activity GO:0004298 20 19 0,000 0,02111032 0,03250758 GO:0070003|threonine-type peptidase activity, ! chromosome condensation GO:0030261 20 19 0,000 0,02111032 0,03249386 ! peptidyl-serine phosphorylation GO:0018105 26 19 0,000 0,02111032 0,03248016 ! regulation of endothelial cell migration GO:0010594 22 19 0,000 0,02111032 0,03246647 ! fatty acid beta-oxidation GO:0006635 21 19 0,000 0,02111032 0,03245278 ! peptide cross-linking GO:0018149 23 19 0,000 0,02111032 0,03243911 ! ventricular cardiac muscle morphogenesis GO:0055010 21 19 0,000 0,02111032 0,03242546 ! beta-catenin binding GO:0008013 23 19 0,000 0,02111032 0,03241181 ! positive regulation of locomotion GO:0040017 21 19 0,000 0,02111032 0,03239817 GO:0050921|positive regulation of chemotaxis, ! cell projection membrane GO:0031253 21 19 0,000 0,02111032 0,03238455 ! positive regulation of inflammatory response GO:0050729 19 19 0,000 0,02111032 0,03237094 ! trans-Golgi network transport vesicle GO:0030140 26 19 0,000 0,02111032 0,03235733 ! sphingolipid biosynthetic process GO:0030148 20 19 0,000 0,02111032 0,03234375 ! vitamin transport GO:0051180 21 19 0,000 0,02111032 0,03233017 ! positive regulation of osteoblast differentiation GO:0045669 22 19 0,000 0,02111032 0,0323166 ! terpenoid metabolic process GO:0006721 20 19 0,000 0,02111032 0,03230304 ! leukotriene biosynthetic process GO:0019370 20 19 0,000 0,02111032 0,0322895 GO:0043450|alkene biosynthetic process, ! nerve development GO:0021675 24 19 0,000 0,02111032 0,03227597 ! retinoid binding GO:0005501 19 19 0,000 0,02111032 0,03226245 GO:0019840|isoprenoid binding, ! regulation of amine transport GO:0051952 23 19 0,000 0,02111032 0,03224894 ! inositol or phosphatidylinositol phosphatase activity GO:0004437 22 19 0,000 0,02111032 0,03223544 ! histone deacetylase activity GO:0004407 20 19 0,000 0,02111032 0,03222195 GO:0033558|protein deacetylase activity, ! regulation of microtubule polymerization or depolymerization GO:0031110 21 19 0,000 0,02111032 0,03220847 ! gluconeogenesis GO:0006094 23 19 0,000 0,02111032 0,03219501 ! post-Golgi vesicle-mediated transport GO:0006892 23 19 0,000 0,02111032 0,03218155 ! microtubule-based transport GO:0010970 20 19 0,000 0,02111032 0,03216811 ! superoxide metabolic process GO:0006801 21 19 0,000 0,02111032 0,03215468 ! C21-steroid hormone metabolic process GO:0008207 20 19 0,000 0,02111032 0,03214126 ! protein amino acid alkylation GO:0008213 22 19 0,000 0,02111032 0,03212785 GO:0006479|protein amino acid methylation, ! L-ascorbic acid binding GO:0031418 19 19 0,000 0,02111032 0,03211445 ! regulation of DNA recombination GO:0000018 38 19 0,000 0,02111032 0,03210107 ! photoreceptor cell maintenance GO:0045494 23 19 0,000 0,02111032 0,03208769 ! positive regulation of cytoskeleton organization GO:0051495 22 19 0,000 0,02111032 0,03207433 ! acetylcholine binding GO:0042166 20 19 0,000 0,02111032 0,03206097 ! heme metabolic process GO:0042168 20 19 0,000 0,02111032 0,03204763 ! SH2 domain binding GO:0042169 25 19 0,000 0,02111032 0,0320343 ! neurotransmitter:sodium symporter activity GO:0005328 21 19 0,000 0,02111032 0,03202098 ! negative regulation of protein catabolic process GO:0042177 19 19 0,000 0,02111032 0,03200767 ! carbohydrate kinase activity GO:0019200 20 19 0,000 0,02111032 0,03199437 ! RNA methyltransferase activity GO:0008173 19 19 0,000 0,02111032 0,03198109 ! RNA-dependent ATPase activity GO:0008186 29 19 0,000 0,02111032 0,03196781 ! body fluid secretion GO:0007589 21 19 0,000 0,02111032 0,03195455 ! neuropeptide hormone activity GO:0005184 25 19 0,000 0,02111032 0,03194129 ! secretory granule membrane GO:0030667 21 19 0,000 0,02111032 0,03192805 ! extracellular-glutamate-gated ion channel activity GO:0005234 23 19 0,000 0,02111032 0,03191482 ! ribonucleoprotein binding GO:0043021 20 19 0,000 0,02111032 0,0319016 ! peptidase activator activity GO:0016504 21 19 0,000 0,02111032 0,03188839 ! transcription elongation regulator activity GO:0003711 20 19 0,000 0,02111032 0,03187519 ! small conjugating protein-specific protease activity GO:0019783 21 19 0,000 0,02111032 0,031862 ! regulation of BMP signaling pathway GO:0030510 20 19 0,000 0,02111032 0,03184882 ! sialyltransferase activity GO:0008373 31 19 0,000 0,02111032 0,03183566 ! ATP-dependent DNA helicase activity GO:0004003 30 19 0,000 0,02111032 0,0318225 ! chaperone binding GO:0051087 21 20 0,000 0,02220955 0,03346569 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 23 20 0,000 0,02220955 0,03345188 ! regulation of anti-apoptosis GO:0045767 20 20 0,000 0,02220955 0,03343807 ! reciprocal meiotic recombination GO:0007131 40 20 0,000 0,02220955 0,03342428 ! protein amino acid ADP-ribosylation GO:0006471 23 20 0,000 0,02220955 0,03341049 ! exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters GO:0016796 30 20 0,000 0,02220955 0,03339672 ! retina development in camera-type eye GO:0060041 24 20 0,000 0,02220955 0,03338296 ! negative regulation of lipid metabolic process GO:0045833 34 20 0,000 0,02220955 0,03336921 ! ovarian follicle development GO:0001541 21 20 0,000 0,02220955 0,03335547 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 33 20 0,000 0,02220955 0,03334175 ! proton-transporting two-sector ATPase complex, proton-transporting domain GO:0033177 21 20 0,000 0,02220955 0,03332803 ! hydrogen peroxide metabolic process GO:0042743 20 20 0,000 0,02220955 0,03331433 ! diencephalon development GO:0021536 22 20 0,000 0,02220955 0,03330063 ! nuclear inner membrane GO:0005637 21 20 0,000 0,02220955 0,03328695 ! regulation of lipid transport GO:0032368 22 20 0,000 0,02220955 0,03327328 ! response to glucocorticoid stimulus GO:0051384 22 20 0,000 0,02220955 0,03325962 ! glutathione metabolic process GO:0006749 21 20 0,000 0,02220955 0,03324598 ! transcriptional repressor complex GO:0017053 23 20 0,000 0,02220955 0,03323234 ! vitamin A metabolic process GO:0006776 20 20 0,000 0,02220955 0,03321871 ! positive regulation of lymphocyte differentiation GO:0045621 30 20 0,000 0,02220955 0,0332051 ! negative regulation of cytokine production GO:0001818 23 20 0,000 0,02220955 0,0331915 ! phosphorus-oxygen lyase activity GO:0016849 21 20 0,000 0,02220955 0,03317791 ! peptide hormone secretion GO:0030072 25 20 0,000 0,02220955 0,03316432 GO:0002790|peptide secretion, ! actin filament-based movement GO:0030048 22 20 0,000 0,02220955 0,03315075 ! Rab GTPase binding GO:0017137 22 20 0,000 0,02220955 0,0331372 ! initiation of viral infection GO:0019059 22 20 0,000 0,02220955 0,03312365 ! voltage-gated anion channel activity GO:0008308 23 20 0,000 0,02220955 0,03311011 ! heterochromatin GO:0000792 20 20 0,000 0,02220955 0,03309659 ! aminoglycan catabolic process GO:0006026 22 20 0,000 0,02220955 0,03308307 ! glycosaminoglycan biosynthetic process GO:0006024 21 20 0,000 0,02220955 0,03306957 ! regulation of chemotaxis GO:0050920 22 20 0,000 0,02220955 0,03305608 ! calcium-independent cell-cell adhesion GO:0016338 27 20 0,000 0,02220955 0,0330426 ! high-density lipoprotein particle GO:0034364 30 20 0,000 0,02220955 0,03302913 ! visual behavior GO:0007632 34 20 0,000 0,02220955 0,03301567 ! regulation of cell-matrix adhesion GO:0001952 26 20 0,000 0,02220955 0,03300222 GO:0010810|regulation of cell-substrate adhesion, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 23 20 0,000 0,02220955 0,03298878 ! immune response-activating cell surface receptor signaling pathway GO:0002429 27 20 0,000 0,02220955 0,03297535 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of nitric oxide biosynthetic process GO:0045428 21 20 0,000 0,02220955 0,03296194 ! vesicle docking during exocytosis GO:0006904 21 20 0,000 0,02220955 0,03294853 ! nucleotide kinase activity GO:0019201 26 20 0,000 0,02220955 0,03293514 ! rRNA binding GO:0019843 22 20 0,000 0,02220955 0,03292176 ! cytolysis GO:0019835 22 20 0,000 0,02220955 0,03290839 ! renal system process GO:0003014 22 20 0,000 0,02220955 0,03289502 ! specific transcriptional repressor activity GO:0016566 23 20 0,000 0,02220955 0,03288167 ! fatty acid transport GO:0015908 23 20 0,000 0,02220955 0,03286833 ! transaminase activity GO:0008483 22 20 0,000 0,02220955 0,03285501 ! activation of JUN kinase activity GO:0007257 22 20 0,000 0,02220955 0,03284169 ! collagen catabolic process GO:0030574 21 20 0,000 0,02220955 0,03282838 ! microvillus GO:0005902 25 20 0,000 0,02220955 0,03281509 ! tumor necrosis factor receptor binding GO:0005164 22 20 0,000 0,02220955 0,0328018 ! connexon complex GO:0005922 23 20 0,000 0,02220955 0,03278852 ! positive regulation of DNA replication GO:0045740 27 21 0,000 0,02330761 0,03439569 ! positive regulation of protein catabolic process GO:0045732 23 21 0,000 0,02330761 0,03438178 ! translational initiation GO:0006413 21 21 0,000 0,02330761 0,03436788 ! NF-kappaB binding GO:0051059 31 21 0,000 0,02330761 0,034354 ! heterotrimeric G-protein complex GO:0005834 23 21 0,000 0,02330761 0,03434012 ! positive regulation of bone remodeling GO:0046852 22 21 0,000 0,02330761 0,03432626 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 25 21 0,000 0,02330761 0,03431241 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! transition metal ion transmembrane transporter activity GO:0046915 25 21 0,000 0,02330761 0,03429857 ! glutathione transferase activity GO:0004364 21 21 0,000 0,02330761 0,03428474 ! voltage-gated calcium channel complex GO:0005891 28 21 0,000 0,02330761 0,03427092 ! glutamate signaling pathway GO:0007215 23 21 0,000 0,02330761 0,03425711 ! regeneration GO:0031099 24 21 0,000 0,02330761 0,03424331 ! MHC class I protein complex GO:0042612 31 21 0,000 0,02330761 0,03422953 ! cellular response to starvation GO:0009267 22 21 0,000 0,02330761 0,03421575 ! peroxisome organization GO:0007031 22 21 0,000 0,02330761 0,03420199 ! vacuole organization GO:0007033 23 21 0,000 0,02330761 0,03418824 ! response to lipopolysaccharide GO:0032496 31 21 0,000 0,02330761 0,0341745 ! neural crest cell development GO:0014032 24 21 0,000 0,02330761 0,03416076 GO:0014033|neural crest cell differentiation, ! nucleobase metabolic process GO:0009112 23 21 0,000 0,02330761 0,03414705 ! regulation of steroid metabolic process GO:0019218 23 21 0,000 0,02330761 0,03413334 ! ribonucleoside monophosphate metabolic process GO:0009161 26 21 0,000 0,02330761 0,03411964 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! monocarboxylic acid transmembrane transporter activity GO:0008028 25 21 0,000 0,02330761 0,03410595 ! pallium development GO:0021543 22 21 0,000 0,02330761 0,03409228 ! synaptic vesicle transport GO:0048489 25 21 0,000 0,02330761 0,03407861 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 21 21 0,000 0,02330761 0,03406496 ! leukocyte homeostasis GO:0001776 22 21 0,000 0,02330761 0,03405132 ! negative regulation of neuron differentiation GO:0045665 22 21 0,000 0,02330761 0,03403769 ! cyclase activity GO:0009975 22 21 0,000 0,02330761 0,03402407 ! aspartate family amino acid metabolic process GO:0009066 24 21 0,000 0,02330761 0,03401046 ! gut development GO:0048565 23 21 0,000 0,02330761 0,03399686 ! calcium-dependent phospholipid binding GO:0005544 22 21 0,000 0,02330761 0,03398327 ! negative regulation of T cell activation GO:0050868 23 21 0,000 0,02330761 0,03396969 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,02330761 0,03395613 ! cellular aldehyde metabolic process GO:0006081 22 21 0,000 0,02330761 0,03394257 ! membrane lipid biosynthetic process GO:0046467 22 21 0,000 0,02330761 0,03392903 ! nucleotide-excision repair, DNA damage removal GO:0000718 22 21 0,000 0,02330761 0,03391549 ! axis specification GO:0009798 25 21 0,000 0,02330761 0,03390197 ! response to alkaloid GO:0043279 27 21 0,000 0,02330761 0,03388846 ! 4 iron, 4 sulfur cluster binding GO:0051539 24 21 0,000 0,02330761 0,03387496 ! response to ethanol GO:0045471 28 21 0,000 0,02330761 0,03386147 ! response to carbohydrate stimulus GO:0009743 24 21 0,000 0,02330761 0,03384799 ! smooth muscle contraction GO:0006939 25 21 0,000 0,02330761 0,03383452 ! ubiquitin binding GO:0043130 25 21 0,000 0,02330761 0,03382106 ! vesicle targeting GO:0006903 22 21 0,000 0,02330761 0,03380761 ! phospholipase A2 activity GO:0004623 32 21 0,000 0,02330761 0,03379417 ! SNARE binding GO:0000149 24 21 0,000 0,02330761 0,03378075 ! interaction with host GO:0051701 26 21 0,000 0,02330761 0,03376733 ! positive regulation of myeloid leukocyte differentiation GO:0002763 26 21 0,000 0,02330761 0,03375393 ! lymphocyte proliferation GO:0046651 24 21 0,000 0,02330761 0,03374053 ! regulation of tumor necrosis factor production GO:0032680 24 21 0,000 0,02330761 0,03372715 ! regulation of interleukin-2 production GO:0032663 21 21 0,000 0,02330761 0,03371378 ! negative regulation of angiogenesis GO:0016525 23 21 0,000 0,02330761 0,03370041 ! cell-cell junction organization GO:0045216 24 21 0,000 0,02330761 0,03368706 ! single-stranded RNA binding GO:0003727 22 21 0,000 0,02330761 0,03367372 ! cyclic nucleotide binding GO:0030551 25 21 0,000 0,02330761 0,03366039 ! caveola GO:0005901 25 21 0,000 0,02330761 0,03364707 ! water-soluble vitamin biosynthetic process GO:0042364 23 21 0,000 0,02330761 0,03363376 ! insulin receptor binding GO:0005158 25 21 0,000 0,02330761 0,03362046 ! pyrimidine nucleotide biosynthetic process GO:0006221 26 21 0,000 0,02330761 0,03360717 ! regulation of multi-organism process GO:0043900 32 21 0,000 0,02330761 0,03359389 ! mRNA export from nucleus GO:0006406 26 22 0,000 0,02440448 0,03516096 ! metencephalon development GO:0022037 25 22 0,000 0,02440448 0,03514708 ! regulation of interferon-gamma production GO:0032649 25 22 0,000 0,02440448 0,03513321 ! hormone secretion GO:0046879 28 22 0,000 0,02440448 0,03511935 ! vesicle docking GO:0048278 24 22 0,000 0,02440448 0,0351055 ! muscle myosin complex GO:0005859 23 22 0,000 0,02440448 0,03509167 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 24 22 0,000 0,02440448 0,03507784 ! microtubule organizing center organization GO:0031023 33 22 0,000 0,02440448 0,03506402 GO:0051297|centrosome organization, ! positive regulation of innate immune response GO:0045089 23 22 0,000 0,02440448 0,03505022 ! sperm motility GO:0030317 23 22 0,000 0,02440448 0,03503643 ! potassium channel regulator activity GO:0015459 29 22 0,000 0,02440448 0,03502264 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor GO:0016620 24 22 0,000 0,02440448 0,03500887 ! vacuolar transport GO:0007034 22 22 0,000 0,02440448 0,03499511 ! oxidoreductase activity, acting on heme group of donors GO:0016675 23 22 0,000 0,02440448 0,03498136 GO:0016676|oxidoreductase activity, acting on heme group of donors, oxygen as acceptor, GO:0004129|cytochrome-c oxidase activity, GO:0015002|heme-copper terminal oxidase activity, ! central nervous system neuron differentiation GO:0021953 24 22 0,000 0,02440448 0,03496762 ! cellular response to reactive oxygen species GO:0034614 26 22 0,000 0,02440448 0,03495389 ! purine ribonucleoside metabolic process GO:0046128 24 22 0,000 0,02440448 0,03494017 GO:0042278|purine nucleoside metabolic process, ! G-protein chemoattractant receptor activity GO:0001637 24 22 0,000 0,02440448 0,03492646 GO:0004950|chemokine receptor activity, ! response to corticosteroid stimulus GO:0031960 25 22 0,000 0,02440448 0,03491277 ! PML body GO:0016605 25 22 0,000 0,02440448 0,03489908 ! osteoblast differentiation GO:0001649 27 22 0,000 0,02440448 0,03488541 ! regulation of foam cell differentiation GO:0010743 28 22 0,000 0,02440448 0,03487174 ! cyclic nucleotide biosynthetic process GO:0009190 23 22 0,000 0,02440448 0,03485809 ! leukotriene metabolic process GO:0006691 23 22 0,000 0,02440448 0,03484445 ! glycosphingolipid metabolic process GO:0006687 23 22 0,000 0,02440448 0,03483081 ! deacetylase activity GO:0019213 23 22 0,000 0,02440448 0,03481719 ! pentose metabolic process GO:0019321 23 22 0,000 0,02440448 0,03480358 ! collagen fibril organization GO:0030199 32 22 0,000 0,02440448 0,03478998 ! regulation of response to biotic stimulus GO:0002831 33 22 0,000 0,02440448 0,03477639 ! positive regulation of adaptive immune response GO:0002821 22 22 0,000 0,02440448 0,03476281 ! peptidyl-serine modification GO:0018209 30 22 0,000 0,02440448 0,03474924 ! DNA-directed RNA polymerase complex GO:0000428 23 22 0,000 0,02440448 0,03473568 GO:0055029|nuclear DNA-directed RNA polymerase complex, ! endoribonuclease activity, producing 5'-phosphomonoesters GO:0016891 32 22 0,000 0,02440448 0,03472214 ! positive regulation of behavior GO:0048520 24 22 0,000 0,02440448 0,0347086 ! regulation of generation of precursor metabolites and energy GO:0043467 25 22 0,000 0,02440448 0,03469507 ! aromatic compound catabolic process GO:0019439 23 22 0,000 0,02440448 0,03468156 ! embryonic epithelial tube formation GO:0001838 25 22 0,000 0,02440448 0,03466805 GO:0001841|neural tube formation, ! telomere organization GO:0032200 43 22 0,000 0,02440448 0,03465456 GO:0000723|telomere maintenance, ! acetyl-CoA catabolic process GO:0046356 24 22 0,000 0,02440448 0,03464107 GO:0006099|tricarboxylic acid cycle, ! protein tetramerization GO:0051262 25 22 0,000 0,02440448 0,0346276 ! glycerol metabolic process GO:0006071 24 22 0,000 0,02440448 0,03461414 ! nuclear chromatin GO:0000790 23 22 0,000 0,02440448 0,03460068 ! cellular iron ion homeostasis GO:0006879 25 22 0,000 0,02440448 0,03458724 ! aminoglycan biosynthetic process GO:0006023 23 22 0,000 0,02440448 0,03457381 ! positive regulation of JAK-STAT cascade GO:0046427 25 22 0,000 0,02440448 0,03456039 ! sterol binding GO:0032934 24 22 0,000 0,02440448 0,03454698 ! calcium-dependent cell-cell adhesion GO:0016339 23 22 0,000 0,02440448 0,03453358 ! digestive system process GO:0022600 25 22 0,000 0,02440448 0,03452019 ! neurotransmitter transporter activity GO:0005326 24 22 0,000 0,02440448 0,03450681 ! organic acid:sodium symporter activity GO:0005343 25 22 0,000 0,02440448 0,03449344 ! nonmotile primary cilium GO:0031513 24 22 0,000 0,02440448 0,03448008 ! negative regulation of myeloid leukocyte differentiation GO:0002762 26 22 0,000 0,02440448 0,03446673 ! base-excision repair GO:0006284 33 22 0,000 0,02440448 0,03445339 ! regulation of chromosome organization GO:0033044 27 22 0,000 0,02440448 0,03444006 ! DNA modification GO:0006304 25 22 0,000 0,02440448 0,03442674 ! detection of chemical stimulus GO:0009593 23 22 0,000 0,02440448 0,03441344 ! positive regulation of tissue remodeling GO:0034105 23 22 0,000 0,02440448 0,03440014 ! GABA-A receptor activity GO:0004890 27 22 0,000 0,02440448 0,03438685 ! response to cytokine stimulus GO:0034097 25 22 0,000 0,02440448 0,03437357 ! steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0033764 24 22 0,000 0,02440448 0,03436031 ! pyrimidine nucleoside metabolic process GO:0006213 27 22 0,000 0,02440448 0,03434705 ! phosphoprotein phosphatase inhibitor activity GO:0004864 25 22 0,000 0,02440448 0,03433381 ! solute:cation antiporter activity GO:0015298 23 22 0,000 0,02440448 0,03432057 ! regulation of transmembrane transport GO:0034762 28 23 0,000 0,02550019 0,03584767 ! protein amino acid O-linked glycosylation GO:0006493 28 23 0,000 0,02550019 0,03583386 ! leukocyte adhesion GO:0007159 26 23 0,000 0,02550019 0,03582006 ! dicarboxylic acid metabolic process GO:0043648 27 23 0,000 0,02550019 0,03580627 ! odontogenesis of dentine-containing tooth GO:0042475 26 23 0,000 0,02550019 0,03579249 ! positive regulation of endocytosis GO:0045807 25 23 0,000 0,02550019 0,03577873 ! mitochondrial membrane organization GO:0007006 25 23 0,000 0,02550019 0,03576497 ! ureteric bud development GO:0001657 24 23 0,000 0,02550019 0,03575123 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 27 23 0,000 0,02550019 0,03573749 ! regulation of insulin secretion GO:0050796 27 23 0,000 0,02550019 0,03572377 ! vitamin biosynthetic process GO:0009110 25 23 0,000 0,02550019 0,03571005 ! negative regulation of neurogenesis GO:0050768 29 23 0,000 0,02550019 0,03569635 ! cholesterol biosynthetic process GO:0006695 29 23 0,000 0,02550019 0,03568266 ! deaminase activity GO:0019239 24 23 0,000 0,02550019 0,03566898 ! sensory perception of pain GO:0019233 26 23 0,000 0,02550019 0,03565531 ! lipid kinase activity GO:0001727 26 23 0,000 0,02550019 0,03564164 ! platelet activation GO:0030168 27 23 0,000 0,02550019 0,03562799 ! proteoglycan biosynthetic process GO:0030166 24 23 0,000 0,02550019 0,03561435 ! positive regulation of intracellular transport GO:0032388 26 23 0,000 0,02550019 0,03560072 ! regulation of blood coagulation GO:0030193 26 23 0,000 0,02550019 0,03558711 ! regulation of cytokine secretion GO:0050707 27 23 0,000 0,02550019 0,0355735 ! fat-soluble vitamin metabolic process GO:0006775 23 23 0,000 0,02550019 0,0355599 ! cellular alkene metabolic process GO:0043449 24 23 0,000 0,02550019 0,03554631 ! aromatic amino acid family metabolic process GO:0009072 25 23 0,000 0,02550019 0,03553273 ! cell surface binding GO:0043498 28 23 0,000 0,02550019 0,03551916 ! porphyrin metabolic process GO:0006778 24 23 0,000 0,02550019 0,03550561 GO:0033013|tetrapyrrole metabolic process, ! ligase activity, forming carbon-sulfur bonds GO:0016877 24 23 0,000 0,02550019 0,03549206 ! regulation of glucose import GO:0046324 28 23 0,000 0,02550019 0,03547853 ! insulin-like growth factor binding GO:0005520 27 23 0,000 0,02550019 0,035465 ! alditol metabolic process GO:0019400 25 23 0,000 0,02550019 0,03545148 ! positive regulation of JUN kinase activity GO:0043507 25 23 0,000 0,02550019 0,03543798 ! pyruvate metabolic process GO:0006090 27 23 0,000 0,02550019 0,03542448 ! zinc ion transport GO:0006829 26 23 0,000 0,02550019 0,035411 ! N-acetylglucosamine metabolic process GO:0006044 26 23 0,000 0,02550019 0,03539752 ! antigen processing and presentation of peptide antigen GO:0048002 30 23 0,000 0,02550019 0,03538406 ! sex determination GO:0007530 25 23 0,000 0,02550019 0,03537061 ! phosphate binding GO:0042301 25 23 0,000 0,02550019 0,03535716 ! positive regulation of leukocyte mediated immunity GO:0002705 24 23 0,000 0,02550019 0,03534373 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of interleukin-6 production GO:0032675 26 23 0,000 0,02550019 0,0353303 ! nuclear-transcribed mRNA catabolic process GO:0000956 26 23 0,000 0,02550019 0,03531689 ! 3',5'-cyclic-nucleotide phosphodiesterase activity GO:0004114 28 23 0,000 0,02550019 0,03530349 ! ubiquitin protein ligase binding GO:0031625 24 23 0,000 0,02550019 0,0352901 ! positive regulation of nuclear division GO:0051785 35 23 0,000 0,02550019 0,03527671 GO:0045840|positive regulation of mitosis, ! synaptogenesis GO:0007416 25 23 0,000 0,02550019 0,03526334 ! regulation of bone mineralization GO:0030500 23 23 0,000 0,02550019 0,03524998 ! neurotransmitter secretion GO:0007269 26 23 0,000 0,02550019 0,03523663 ! ethanolamine and derivative metabolic process GO:0042439 34 23 0,000 0,02550019 0,03522328 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 25 23 0,000 0,02550019 0,03520995 ! leukocyte proliferation GO:0070661 26 23 0,000 0,02550019 0,03519663 GO:0032943|mononuclear cell proliferation, ! myosin II complex GO:0016460 24 23 0,000 0,02550019 0,03518332 ! growth cone GO:0030426 27 24 0,000 0,02659472 0,0366796 ! oligosaccharide metabolic process GO:0009311 29 24 0,000 0,02659472 0,03666574 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors GO:0016706 24 24 0,000 0,02659472 0,03665189 ! pancreas development GO:0031016 27 24 0,000 0,02659472 0,03663805 ! androgen receptor binding GO:0050681 34 24 0,000 0,02659472 0,03662422 ! calcium channel complex GO:0034704 31 24 0,000 0,02659472 0,0366104 ! coenzyme catabolic process GO:0009109 26 24 0,000 0,02659472 0,03659659 ! negative regulation of cell development GO:0010721 30 24 0,000 0,02659472 0,03658279 ! cardiac muscle tissue morphogenesis GO:0055008 27 24 0,000 0,02659472 0,036569 GO:0060415|muscle tissue morphogenesis, ! phosphatase inhibitor activity GO:0019212 27 24 0,000 0,02659472 0,03655522 ! regulation of ARF GTPase activity GO:0032312 28 24 0,000 0,02659472 0,03654145 ! regulation of oxidoreductase activity GO:0051341 24 24 0,000 0,02659472 0,03652769 ! RNA splicing factor activity, transesterification mechanism GO:0031202 25 24 0,000 0,02659472 0,03651394 ! Rho GTPase binding GO:0017048 36 24 0,000 0,02659472 0,03650021 ! regulation of glucose transport GO:0010827 29 24 0,000 0,02659472 0,03648648 ! serine family amino acid metabolic process GO:0009069 27 24 0,000 0,02659472 0,03647276 ! intramolecular transferase activity GO:0016866 26 24 0,000 0,02659472 0,03645906 ! phosphoinositide phospholipase C activity GO:0004435 28 24 0,000 0,02659472 0,03644536 GO:0004434|inositol or phosphatidylinositol phosphodiesterase activity, ! Z disc GO:0030018 27 24 0,000 0,02659472 0,03643168 ! protein stabilization GO:0050821 24 24 0,000 0,02659472 0,036418 ! protein import into nucleus, translocation GO:0000060 27 24 0,000 0,02659472 0,03640433 ! embryonic pattern specification GO:0009880 29 24 0,000 0,02659472 0,03639068 ! RNA polymerase complex GO:0030880 25 24 0,000 0,02659472 0,03637703 ! cellular polysaccharide biosynthetic process GO:0033692 24 24 0,000 0,02659472 0,0363634 ! glucosamine metabolic process GO:0006041 27 24 0,000 0,02659472 0,03634978 ! small conjugating protein binding GO:0032182 29 24 0,000 0,02659472 0,03633616 ! regulation of transcription factor import into nucleus GO:0042990 26 24 0,000 0,02659472 0,03632256 ! chemokine binding GO:0019956 26 24 0,000 0,02659472 0,03630896 ! catechol metabolic process GO:0009712 29 24 0,000 0,02659472 0,03629538 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! regulation of smooth muscle contraction GO:0006940 28 24 0,000 0,02659472 0,03628181 ! NAD+ ADP-ribosyltransferase activity GO:0003950 26 24 0,000 0,02659472 0,03626824 ! multicellular organismal response to stress GO:0033555 27 24 0,000 0,02659472 0,03625469 ! cell aging GO:0007569 47 24 0,000 0,02659472 0,03624115 ! immune response-activating signal transduction GO:0002757 31 24 0,000 0,02659472 0,03622761 GO:0002764|immune response-regulating signal transduction, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 26 24 0,000 0,02659472 0,03621409 ! fibroblast growth factor receptor signaling pathway GO:0008543 27 24 0,000 0,02659472 0,03620058 ! voltage-gated calcium channel activity GO:0005245 31 24 0,000 0,02659472 0,03618708 ! cyclic-nucleotide phosphodiesterase activity GO:0004112 29 24 0,000 0,02659472 0,03617358 ! metallocarboxypeptidase activity GO:0004181 24 24 0,000 0,02659472 0,0361601 ! caspase regulator activity GO:0043028 26 24 0,000 0,02659472 0,03614663 ! regulation of microtubule cytoskeleton organization GO:0070507 35 24 0,000 0,02659472 0,03613317 ! 3'-5' exonuclease activity GO:0008408 43 24 0,000 0,02659472 0,03611971 ! selenium binding GO:0008430 24 24 0,000 0,02659472 0,03610627 ! spindle pole GO:0000922 35 24 0,000 0,02659472 0,03609284 ! Rho GTPase activator activity GO:0005100 28 24 0,000 0,02659472 0,03607942 ! site of polarized growth GO:0030427 28 25 0,000 0,02768809 0,03754875 ! phenol metabolic process GO:0018958 31 25 0,000 0,02768809 0,0375348 ! regulation of lipid biosynthetic process GO:0046890 35 25 0,000 0,02768809 0,03752085 ! protein amino acid acylation GO:0043543 28 25 0,000 0,02768809 0,03750692 ! aromatase activity GO:0070330 28 25 0,000 0,02768809 0,037493 ! cholesterol homeostasis GO:0042632 27 25 0,000 0,02768809 0,03747909 GO:0055092|sterol homeostasis, ! positive regulation of epithelial cell proliferation GO:0050679 29 25 0,000 0,02768809 0,03746519 ! oxidoreductase activity, acting on the CH-NH group of donors GO:0016645 29 25 0,000 0,02768809 0,03745129 ! response to starvation GO:0042594 26 25 0,000 0,02768809 0,03743741 ! dynein complex GO:0030286 28 25 0,000 0,02768809 0,03742354 ! ARF GTPase activator activity GO:0008060 29 25 0,000 0,02768809 0,03740968 ! regulation of behavior GO:0050795 27 25 0,000 0,02768809 0,03739583 ! regulation of biomineral formation GO:0070167 25 25 0,000 0,02768809 0,03738199 ! hexose biosynthetic process GO:0019319 31 25 0,000 0,02768809 0,03736816 ! group transfer coenzyme metabolic process GO:0006752 25 25 0,000 0,02768809 0,03735434 ! hormone transport GO:0009914 31 25 0,000 0,02768809 0,03734053 ! response to molecule of bacterial origin GO:0002237 35 25 0,000 0,02768809 0,03732673 ! cell adhesion molecule binding GO:0050839 29 25 0,000 0,02768809 0,03731294 ! regulation of coagulation GO:0050818 28 25 0,000 0,02768809 0,03729917 ! myeloid leukocyte differentiation GO:0002573 28 25 0,000 0,02768809 0,0372854 ! acetyl-CoA metabolic process GO:0006084 27 25 0,000 0,02768809 0,03727164 ! chromosome, telomeric region GO:0000781 38 25 0,000 0,02768809 0,03725789 ! molting cycle process GO:0022404 28 25 0,000 0,02768809 0,03724415 GO:0022405|hair cycle process, GO:0001942|hair follicle development, ! collagen metabolic process GO:0032963 26 25 0,000 0,02768809 0,03723042 ! xenobiotic metabolic process GO:0006805 27 25 0,000 0,02768809 0,03721671 ! phototransduction GO:0007602 27 25 0,000 0,02768809 0,037203 ! negative regulation of response to external stimulus GO:0032102 30 25 0,000 0,02768809 0,0371893 ! regulation of endothelial cell proliferation GO:0001936 29 25 0,000 0,02768809 0,03717561 ! protein phosphatase binding GO:0019903 27 25 0,000 0,02768809 0,03716193 ! negative regulation of DNA replication GO:0008156 31 25 0,000 0,02768809 0,03714827 ! multicellular organismal catabolic process GO:0044243 27 25 0,000 0,02768809 0,03713461 ! autophagy GO:0006914 28 25 0,000 0,02768809 0,03712096 ! steroid dehydrogenase activity GO:0016229 27 25 0,000 0,02768809 0,03710733 ! response to ionizing radiation GO:0010212 37 25 0,000 0,02768809 0,0370937 ! DNA-directed DNA polymerase activity GO:0003887 30 25 0,000 0,02768809 0,03708008 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 31 26 0,000 0,02878028 0,03852861 ! positive regulation of cell adhesion GO:0045785 34 26 0,000 0,02878028 0,03851448 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen GO:0016712 29 26 0,000 0,02878028 0,03850035 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen GO:0016709 28 26 0,000 0,02878028 0,03848624 ! positive regulation of lipid metabolic process GO:0045834 27 26 0,000 0,02878028 0,03847214 ! hair cycle GO:0042633 29 26 0,000 0,02878028 0,03845804 GO:0042303|molting cycle, ! thyroid hormone receptor binding GO:0046966 30 26 0,000 0,02878028 0,03844396 ! polysaccharide catabolic process GO:0000272 39 26 0,000 0,02878028 0,03842989 ! peptidyl-tyrosine phosphorylation GO:0018108 30 26 0,000 0,02878028 0,03841583 ! early endosome membrane GO:0031901 31 26 0,000 0,02878028 0,03840178 ! negative regulation of protein kinase cascade GO:0010741 40 26 0,000 0,02878028 0,03838774 ! iron ion homeostasis GO:0055072 29 26 0,000 0,02878028 0,03837371 ! glycolipid metabolic process GO:0006664 36 26 0,000 0,02878028 0,03835969 ! GABA receptor activity GO:0016917 31 26 0,000 0,02878028 0,03834568 ! PDZ domain binding GO:0030165 28 26 0,000 0,02878028 0,03833168 ! positive regulation of protein secretion GO:0050714 29 26 0,000 0,02878028 0,03831769 ! regulation of cellular carbohydrate metabolic process GO:0010675 29 26 0,000 0,02878028 0,03830371 ! AP-type membrane coat adaptor complex GO:0030119 30 26 0,000 0,02878028 0,03828974 GO:0030131|clathrin adaptor complex, ! neuromuscular process controlling balance GO:0050885 32 26 0,000 0,02878028 0,03827578 ! endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters GO:0016893 45 26 0,000 0,02878028 0,03826183 ! fatty acid binding GO:0005504 28 26 0,000 0,02878028 0,03824789 ! blastocyst development GO:0001824 27 26 0,000 0,02878028 0,03823396 ! regulation of JUN kinase activity GO:0043506 28 26 0,000 0,02878028 0,03822004 ! lysine N-acetyltransferase activity GO:0004468 29 26 0,000 0,02878028 0,03820614 GO:0004402|histone acetyltransferase activity, ! regulation of smooth muscle cell proliferation GO:0048660 30 26 0,000 0,02878028 0,03819224 ! positive regulation of cell projection organization GO:0031346 27 26 0,000 0,02878028 0,03817835 ! iron ion transport GO:0006826 33 26 0,000 0,02878028 0,03816447 ! regulation of synaptic plasticity GO:0048167 36 26 0,000 0,02878028 0,0381506 ! glucose transport GO:0015758 27 26 0,000 0,02878028 0,03813675 ! spinal cord development GO:0021510 30 26 0,000 0,02878028 0,0381229 ! histone deacetylase complex GO:0000118 29 26 0,000 0,02878028 0,03810906 ! response to endoplasmic reticulum stress GO:0034976 30 26 0,000 0,02878028 0,03809523 ! regulation of peptide secretion GO:0002791 30 26 0,000 0,02878028 0,03808141 ! regulation of production of molecular mediator of immune response GO:0002700 27 26 0,000 0,02878028 0,03806761 ! RNA helicase activity GO:0003724 46 26 0,000 0,02878028 0,03805381 ! brush border GO:0005903 30 26 0,000 0,02878028 0,03804002 ! gap junction GO:0005921 29 26 0,000 0,02878028 0,03802624 ! anion:cation symporter activity GO:0015296 29 26 0,000 0,02878028 0,03801248 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 39 27 0,000 0,0298713 0,0394392 ! RNA export from nucleus GO:0006405 31 27 0,000 0,0298713 0,03942493 ! mRNA catabolic process GO:0006402 31 27 0,000 0,0298713 0,03941068 ! myelination GO:0042552 31 27 0,000 0,0298713 0,03939643 ! trans-Golgi network GO:0005802 31 27 0,000 0,0298713 0,03938219 ! transferase activity, transferring nitrogenous groups GO:0016769 29 27 0,000 0,0298713 0,03936796 ! solute:solute antiporter activity GO:0015300 28 27 0,000 0,0298713 0,03935374 ! vasculogenesis GO:0001570 32 27 0,000 0,0298713 0,03933954 ! hexose transport GO:0008645 28 27 0,000 0,0298713 0,03932534 GO:0015749|monosaccharide transport, ! regulation of innate immune response GO:0045088 28 27 0,000 0,0298713 0,03931115 ! spindle organization GO:0007051 38 27 0,000 0,0298713 0,03929698 ! cellular response to oxidative stress GO:0034599 32 27 0,000 0,0298713 0,03928281 ! response to organic cyclic substance GO:0014070 34 27 0,000 0,0298713 0,03926865 ! cell fate determination GO:0001709 29 27 0,000 0,0298713 0,03925451 ! lipid oxidation GO:0034440 29 27 0,000 0,0298713 0,03924037 GO:0019395|fatty acid oxidation, ! fatty acid catabolic process GO:0009062 31 27 0,000 0,0298713 0,03922625 ! collagen binding GO:0005518 29 27 0,000 0,0298713 0,03921213 ! carboxy-lyase activity GO:0016831 27 27 0,000 0,0298713 0,03919803 ! phospholipid transporter activity GO:0005548 30 27 0,000 0,0298713 0,03918393 ! liver development GO:0001889 33 27 0,000 0,0298713 0,03916985 ! mitotic sister chromatid segregation GO:0000070 46 27 0,000 0,0298713 0,03915577 ! determination of bilateral symmetry GO:0009855 32 27 0,000 0,0298713 0,03914171 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! integrin complex GO:0008305 30 27 0,000 0,0298713 0,03912765 ! membrane docking GO:0022406 29 27 0,000 0,0298713 0,03911361 ! detection of light stimulus involved in sensory perception GO:0050962 29 27 0,000 0,0298713 0,03909958 GO:0050908|detection of light stimulus involved in visual perception, ! fat cell differentiation GO:0045444 30 27 0,000 0,0298713 0,03908555 ! multicellular organismal macromolecule metabolic process GO:0044259 28 27 0,000 0,0298713 0,03907154 ! respiratory gaseous exchange GO:0007585 30 27 0,000 0,0298713 0,03905753 ! phospholipid transport GO:0015914 29 27 0,000 0,0298713 0,03904354 ! sarcoplasmic reticulum GO:0016529 29 27 0,000 0,0298713 0,03902955 ! aminopeptidase activity GO:0004177 33 27 0,000 0,0298713 0,03901558 ! cellular response to nutrient levels GO:0031669 28 27 0,000 0,0298713 0,03900162 ! RNA polymerase II transcription factor activity, enhancer binding GO:0003705 33 27 0,000 0,0298713 0,03898766 ! biogenic amine biosynthetic process GO:0042401 29 27 0,000 0,0298713 0,03897372 ! negative regulation of transcription regulator activity GO:0090048 32 27 0,000 0,0298713 0,03895978 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 29 27 0,000 0,0298713 0,03894586 ! ligand-dependent nuclear receptor transcription coactivator activity GO:0030374 31 28 0,000 0,03096116 0,04035238 ! Golgi stack GO:0005795 30 28 0,000 0,03096116 0,04033797 ! male gonad development GO:0008584 32 28 0,000 0,03096116 0,04032357 ! regulation of fatty acid metabolic process GO:0019217 41 28 0,000 0,03096116 0,04030918 ! lipoprotein binding GO:0008034 31 28 0,000 0,03096116 0,0402948 ! mesoderm formation GO:0001707 34 28 0,000 0,03096116 0,04028043 ! negative regulation of MAP kinase activity GO:0043407 30 28 0,000 0,03096116 0,04026607 ! peptidyl-tyrosine modification GO:0018212 32 28 0,000 0,03096116 0,04025172 ! deoxyribonuclease activity GO:0004536 56 28 0,000 0,03096116 0,04023738 ! nicotinamide metabolic process GO:0006769 32 28 0,000 0,03096116 0,04022305 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 31 28 0,000 0,03096116 0,04020873 ! regulation of osteoblast differentiation GO:0045667 33 28 0,000 0,03096116 0,04019442 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines GO:0016814 30 28 0,000 0,03096116 0,04018012 ! negative regulation of neuron apoptosis GO:0043524 39 28 0,000 0,03096116 0,04016583 ! tissue homeostasis GO:0001894 31 28 0,000 0,03096116 0,04015155 GO:0048871|multicellular organismal homeostasis, ! DNA damage checkpoint GO:0000077 48 28 0,000 0,03096116 0,04013728 ! regulation of carbohydrate metabolic process GO:0006109 31 28 0,000 0,03096116 0,04012303 ! sister chromatid segregation GO:0000819 49 28 0,000 0,03096116 0,04010878 ! post-embryonic development GO:0009791 32 28 0,000 0,03096116 0,04009454 ! complement activation, classical pathway GO:0006958 33 28 0,000 0,03096116 0,04008031 ! detection of visible light GO:0009584 30 28 0,000 0,03096116 0,04006609 ! calcium-mediated signaling GO:0019722 30 28 0,000 0,03096116 0,04005189 ! receptor regulator activity GO:0030545 31 28 0,000 0,03096116 0,04003769 ! acetylgalactosaminyltransferase activity GO:0008376 33 28 0,000 0,03096116 0,0400235 ! symbiosis, encompassing mutualism through parasitism GO:0044403 33 28 0,000 0,03096116 0,04000932 ! response to heat GO:0009408 33 28 0,000 0,03096116 0,03999515 ! response to xenobiotic stimulus GO:0009410 31 28 0,000 0,03096116 0,039981 ! response to hydrogen peroxide GO:0042542 32 29 0,000 0,03204985 0,04137221 ! hormone binding GO:0042562 31 29 0,000 0,03204985 0,04135757 ! establishment or maintenance of cell polarity GO:0007163 34 29 0,000 0,03204985 0,04134295 ! NADP or NADPH binding GO:0050661 33 29 0,000 0,03204985 0,04132834 ! nucleotide receptor activity, G-protein coupled GO:0001608 31 29 0,000 0,03204985 0,04131373 GO:0045028|purinergic nucleotide receptor activity, G-protein coupled, ! mitochondrial intermembrane space GO:0005758 41 29 0,000 0,03204985 0,04129914 ! erythrocyte differentiation GO:0030218 35 29 0,000 0,03204985 0,04128456 ! ceramide metabolic process GO:0006672 29 29 0,000 0,03204985 0,04126998 ! replication fork GO:0005657 42 29 0,000 0,03204985 0,04125542 ! camera-type eye morphogenesis GO:0048593 36 29 0,000 0,03204985 0,04124087 ! monosaccharide biosynthetic process GO:0046364 35 29 0,000 0,03204985 0,04122633 ! negative regulation of lymphocyte activation GO:0051250 32 29 0,000 0,03204985 0,0412118 ! alkaloid metabolic process GO:0009820 33 29 0,000 0,03204985 0,04119727 ! icosanoid biosynthetic process GO:0046456 30 29 0,000 0,03204985 0,04118276 ! regulation of pH GO:0006885 30 29 0,000 0,03204985 0,04116826 ! amino sugar metabolic process GO:0006040 41 29 0,000 0,03204985 0,04115377 ! ER-nuclear signaling pathway GO:0006984 32 29 0,000 0,03204985 0,04113929 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 34 29 0,000 0,03204985 0,04112482 ! phospholipase C activity GO:0004629 43 29 0,000 0,03204985 0,04111036 ! response to mechanical stimulus GO:0009612 33 29 0,000 0,03204985 0,04109591 ! clathrin coated vesicle membrane GO:0030665 33 29 0,000 0,03204985 0,04108147 ! sodium channel activity GO:0005272 33 29 0,000 0,03204985 0,04106704 ! sarcoplasm GO:0016528 31 29 0,000 0,03204985 0,04105262 ! detection of light stimulus GO:0009583 31 29 0,000 0,03204985 0,04103821 ! spermatid development GO:0007286 30 29 0,000 0,03204985 0,04102381 ! DNA polymerase activity GO:0034061 34 29 0,000 0,03204985 0,04100942 ! peptidyl-prolyl cis-trans isomerase activity GO:0003755 31 29 0,000 0,03204985 0,04099504 ! sarcolemma GO:0042383 30 29 0,000 0,03204985 0,04098067 ! tumor necrosis factor receptor superfamily binding GO:0032813 31 29 0,000 0,03204985 0,04096631 ! galactosyltransferase activity GO:0008378 33 29 0,000 0,03204985 0,04095197 ! establishment of vesicle localization GO:0051650 30 29 0,000 0,03204985 0,04093763 ! transforming growth factor beta receptor signaling pathway GO:0007179 34 30 0,000 0,03313738 0,04231192 ! mitochondrial nucleoid GO:0042645 44 30 0,000 0,03313738 0,04229712 GO:0009295|nucleoid, ! cholesterol transport GO:0030301 33 30 0,000 0,03313738 0,04228232 GO:0015918|sterol transport, ! histone-lysine N-methyltransferase activity GO:0018024 34 30 0,000 0,03313738 0,04226754 GO:0016278|lysine N-methyltransferase activity, GO:0016279|protein-lysine N-methyltransferase activity, ! cellular carbohydrate biosynthetic process GO:0034637 30 30 0,000 0,03313738 0,04225276 ! scavenger receptor activity GO:0005044 39 30 0,000 0,03313738 0,042238 ! spliceosome assembly GO:0000245 34 30 0,000 0,03313738 0,04222325 ! oxidoreductase activity, acting on peroxide as acceptor GO:0016684 39 30 0,000 0,03313738 0,0422085 GO:0004601|peroxidase activity, ! mesoderm morphogenesis GO:0048332 37 30 0,000 0,03313738 0,04219377 ! metanephros development GO:0001656 31 30 0,000 0,03313738 0,04217905 ! glutamate receptor activity GO:0008066 35 30 0,000 0,03313738 0,04216434 ! cyclic nucleotide metabolic process GO:0009187 31 30 0,000 0,03313738 0,04214964 ! positive regulation of MAPKKK cascade GO:0043410 36 30 0,000 0,03313738 0,04213495 ! regulation of macrophage differentiation GO:0045649 37 30 0,000 0,03313738 0,04212026 ! positive regulation of myeloid cell differentiation GO:0045639 37 30 0,000 0,03313738 0,04210559 ! negative regulation of myeloid cell differentiation GO:0045638 35 30 0,000 0,03313738 0,04209093 ! cis-trans isomerase activity GO:0016859 32 30 0,000 0,03313738 0,04207628 ! myeloid leukocyte activation GO:0002274 36 30 0,000 0,03313738 0,04206164 ! negative regulation of protein transport GO:0051224 34 30 0,000 0,03313738 0,04204701 ! condensed nuclear chromosome GO:0000794 31 30 0,000 0,03313738 0,04203239 ! protein-lipid complex GO:0032994 41 30 0,000 0,03313738 0,04201778 GO:0034358|plasma lipoprotein particle, ! circadian rhythm GO:0007623 37 30 0,000 0,03313738 0,04200318 ! negative regulation of protein modification process GO:0031400 34 30 0,000 0,03313738 0,04198859 ! phosphatase binding GO:0019902 34 30 0,000 0,03313738 0,04197401 ! acute-phase response GO:0006953 44 30 0,000 0,03313738 0,04195944 ! segmentation GO:0035282 37 30 0,000 0,03313738 0,04194488 ! cation-transporting ATPase activity GO:0019829 32 30 0,000 0,03313738 0,04193034 ! antigen binding GO:0003823 33 30 0,000 0,03313738 0,0419158 ! regulation of systemic arterial blood pressure GO:0003073 33 30 0,000 0,03313738 0,04190127 ! Golgi-associated vesicle membrane GO:0030660 37 30 0,000 0,03313738 0,04188675 ! ensheathment of neurons GO:0007272 35 30 0,000 0,03313738 0,04187224 GO:0008366|axon ensheathment, ! JAK-STAT cascade GO:0007259 43 30 0,000 0,03313738 0,04185774 ! regulation of microtubule-based process GO:0032886 41 30 0,000 0,03313738 0,04184325 ! vesicle localization GO:0051648 31 30 0,000 0,03313738 0,04182877 ! negative regulation of cell adhesion GO:0007162 34 31 0,000 0,03422374 0,04318513 ! maintenance of protein location in cell GO:0032507 32 31 0,000 0,03422374 0,0431702 ! acrosomal vesicle GO:0001669 34 31 0,000 0,03422374 0,04315527 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,03422374 0,04314036 ! protein targeting to membrane GO:0006612 35 31 0,000 0,03422374 0,04312546 ! regulation of axonogenesis GO:0050770 37 31 0,000 0,03422374 0,04311057 ! regulation of T cell differentiation GO:0045580 43 31 0,000 0,03422374 0,04309569 ! formation of primary germ layer GO:0001704 37 31 0,000 0,03422374 0,04308082 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors GO:0016903 33 31 0,000 0,03422374 0,04306596 ! endocytic vesicle GO:0030139 33 31 0,000 0,03422374 0,04305111 ! pyridine nucleotide metabolic process GO:0019362 35 31 0,000 0,03422374 0,04303627 ! spermatid differentiation GO:0048515 32 31 0,000 0,03422374 0,04302144 ! negative regulation of catabolic process GO:0009895 34 31 0,000 0,03422374 0,04300662 ! neuron fate commitment GO:0048663 44 31 0,000 0,03422374 0,04299181 ! regulation of cellular catabolic process GO:0031329 35 31 0,000 0,03422374 0,04297701 ! regulation of JAK-STAT cascade GO:0046425 37 31 0,000 0,03422374 0,04296222 ! response to calcium ion GO:0051592 34 31 0,000 0,03422374 0,04294744 ! morphogenesis of embryonic epithelium GO:0016331 36 31 0,000 0,03422374 0,04293267 ! macromolecular complex disassembly GO:0032984 37 31 0,000 0,03422374 0,04291791 ! cell junction assembly GO:0034329 36 31 0,000 0,03422374 0,04290316 ! drug binding GO:0008144 34 31 0,000 0,03422374 0,04288843 ! positive regulation of T cell proliferation GO:0042102 38 31 0,000 0,03422374 0,0428737 ! peptide transport GO:0015833 36 31 0,000 0,03422374 0,04285898 ! DNA integrity checkpoint GO:0031570 51 31 0,000 0,03422374 0,04284427 ! peripheral nervous system development GO:0007422 35 31 0,000 0,03422374 0,04282957 ! I band GO:0031674 34 31 0,000 0,03422374 0,04281489 ! BMP signaling pathway GO:0030509 33 31 0,000 0,03422374 0,04280021 ! adult locomotory behavior GO:0008344 37 31 0,000 0,03422374 0,04278554 ! gene silencing GO:0016458 33 31 0,000 0,03422374 0,04277088 ! negative regulation of adenylate cyclase activity GO:0007194 39 32 0,000 0,03530894 0,04411199 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! negative regulation of secretion GO:0051048 37 32 0,000 0,03530894 0,04409689 ! negative regulation of DNA metabolic process GO:0051053 38 32 0,000 0,03530894 0,0440818 ! phosphotransferase activity, phosphate group as acceptor GO:0016776 49 32 0,000 0,03530894 0,04406672 ! meiosis I GO:0007127 53 32 0,000 0,03530894 0,04405165 ! GPI anchor biosynthetic process GO:0006506 35 32 0,000 0,03530894 0,04403659 GO:0006505|GPI anchor metabolic process, ! unsaturated fatty acid biosynthetic process GO:0006636 33 32 0,000 0,03530894 0,04402154 ! sterol biosynthetic process GO:0016126 40 32 0,000 0,03530894 0,0440065 ! vesicle coat GO:0030120 39 32 0,000 0,03530894 0,04399147 ! cytokine production GO:0001816 32 32 0,000 0,03530894 0,04397645 ! regulation of calcium ion transport GO:0051924 37 32 0,000 0,03530894 0,04396144 ! proteoglycan metabolic process GO:0006029 34 32 0,000 0,03530894 0,04394644 ! sphingoid metabolic process GO:0046519 33 32 0,000 0,03530894 0,04393145 ! multicellular organismal metabolic process GO:0044236 35 32 0,000 0,03530894 0,04391647 ! oxygen binding GO:0019825 33 32 0,000 0,03530894 0,04390151 ! leukocyte chemotaxis GO:0030595 32 32 0,000 0,03530894 0,04388655 GO:0060326|cell chemotaxis, ! negative regulation of leukocyte activation GO:0002695 35 32 0,000 0,03530894 0,0438716 ! hormone biosynthetic process GO:0042446 32 32 0,000 0,03530894 0,04385666 ! double-stranded RNA binding GO:0003725 35 32 0,000 0,03530894 0,04384174 ! microtubule organizing center part GO:0044450 46 32 0,000 0,03530894 0,04382682 ! platelet alpha granule lumen GO:0031093 35 33 0,000 0,03639298 0,045157 ! DNA helicase activity GO:0003678 55 33 0,000 0,03639298 0,04514165 ! neural tube development GO:0021915 37 33 0,000 0,03639298 0,04512631 ! oxidoreductase activity, acting on sulfur group of donors GO:0016667 34 33 0,000 0,03639298 0,04511097 ! pigment biosynthetic process GO:0046148 35 33 0,000 0,03639298 0,04509565 ! organelle envelope lumen GO:0031970 46 33 0,000 0,03639298 0,04508034 ! regulation of cellular ketone metabolic process GO:0010565 46 33 0,000 0,03639298 0,04506503 ! negative regulation of DNA binding GO:0043392 39 33 0,000 0,03639298 0,04504974 ! NAD or NADH binding GO:0051287 36 33 0,000 0,03639298 0,04503446 ! nucleotide catabolic process GO:0009166 35 33 0,000 0,03639298 0,04501919 ! B cell differentiation GO:0030183 37 33 0,000 0,03639298 0,04500393 ! aerobic respiration GO:0009060 35 33 0,000 0,03639298 0,04498868 ! embryonic organ development GO:0048568 41 33 0,000 0,03639298 0,04497344 ! placenta development GO:0001890 39 33 0,000 0,03639298 0,04495821 ! protein serine/threonine phosphatase complex GO:0008287 37 33 0,000 0,03639298 0,04494299 ! tissue remodeling GO:0048771 37 33 0,000 0,03639298 0,04492778 ! flagellum GO:0019861 34 33 0,000 0,03639298 0,04491258 ! L-amino acid transmembrane transporter activity GO:0015179 37 33 0,000 0,03639298 0,04489739 ! Rho protein signal transduction GO:0007266 35 33 0,000 0,03639298 0,04488221 ! cysteine-type endopeptidase inhibitor activity GO:0004869 35 33 0,000 0,03639298 0,04486705 ! odontogenesis GO:0042476 39 34 0,000 0,03747586 0,04618646 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,03747586 0,04617086 ! lipid homeostasis GO:0055088 37 34 0,000 0,03747586 0,04615528 ! telencephalon development GO:0021537 36 34 0,000 0,03747586 0,0461397 ! clathrin coat GO:0030118 41 34 0,000 0,03747586 0,04612413 ! cell growth GO:0016049 36 34 0,000 0,03747586 0,04610858 ! protein polymerization GO:0051258 38 34 0,000 0,03747586 0,04609303 ! condensed chromosome kinetochore GO:0000777 52 34 0,000 0,03747586 0,0460775 ! learning GO:0007612 51 34 0,000 0,03747586 0,04606197 ! keratinization GO:0031424 40 34 0,000 0,03747586 0,04604646 ! ovulation cycle process GO:0022602 35 34 0,000 0,03747586 0,04603095 ! regulation of striated muscle tissue development GO:0016202 40 34 0,000 0,03747586 0,04601546 ! steroid hormone receptor binding GO:0035258 44 34 0,000 0,03747586 0,04599998 ! regulation of protein import into nucleus GO:0042306 36 34 0,000 0,03747586 0,0459845 ! erythrocyte homeostasis GO:0034101 40 34 0,000 0,03747586 0,04596904 ! amino acid binding GO:0016597 40 34 0,000 0,03747586 0,04595359 ! regulation of protein stability GO:0031647 35 34 0,000 0,03747586 0,04593815 ! specific RNA polymerase II transcription factor activity GO:0003704 41 34 0,000 0,03747586 0,04592272 ! glycogen metabolic process GO:0005977 48 34 0,000 0,03747586 0,0459073 ! pyrimidine nucleotide metabolic process GO:0006220 41 34 0,000 0,03747586 0,04589189 ! acetylglucosaminyltransferase activity GO:0008375 40 34 0,000 0,03747586 0,04587649 ! epithelial tube morphogenesis GO:0060562 38 34 0,000 0,03747586 0,0458611 ! positive regulation of transcription factor activity GO:0051091 49 35 0,000 0,03855758 0,04716903 GO:0090047|positive regulation of transcription regulator activity, ! positive regulation of DNA metabolic process GO:0051054 53 35 0,000 0,03855758 0,04715322 ! response to estrogen stimulus GO:0043627 48 35 0,000 0,03855758 0,04713741 ! inner ear morphogenesis GO:0042472 46 35 0,000 0,03855758 0,04712162 ! MHC protein complex GO:0042611 50 35 0,000 0,03855758 0,04710584 ! alcohol biosynthetic process GO:0046165 41 35 0,000 0,03855758 0,04709007 ! vesicle lumen GO:0031983 38 35 0,000 0,03855758 0,04707431 GO:0060205|cytoplasmic membrane-bounded vesicle lumen, ! female gonad development GO:0008585 37 35 0,000 0,03855758 0,04705856 ! mesenchymal cell development GO:0014031 40 35 0,000 0,03855758 0,04704282 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! neutral lipid metabolic process GO:0006638 47 35 0,000 0,03855758 0,0470271 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 37 35 0,000 0,03855758 0,04701138 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 41 35 0,000 0,03855758 0,04699567 ! regulation of proteolysis GO:0030162 37 35 0,000 0,03855758 0,04697997 ! ovulation cycle GO:0042698 37 35 0,000 0,03855758 0,04696429 ! intramolecular oxidoreductase activity GO:0016860 35 35 0,000 0,03855758 0,04694861 ! positive regulation of catabolic process GO:0009896 38 35 0,000 0,03855758 0,04693295 ! collagen GO:0005581 54 35 0,000 0,03855758 0,04691729 ! glucan metabolic process GO:0044042 49 35 0,000 0,03855758 0,04690165 GO:0006073|cellular glucan metabolic process, ! regulation of muscle development GO:0048634 42 35 0,000 0,03855758 0,04688601 ! ER to Golgi vesicle-mediated transport GO:0006888 43 35 0,000 0,03855758 0,04687039 ! histone methyltransferase activity GO:0042054 40 35 0,000 0,03855758 0,04685478 ! cation:sugar symporter activity GO:0005402 37 35 0,000 0,03855758 0,04683918 GO:0005351|sugar:hydrogen symporter activity, ! carbohydrate homeostasis GO:0033500 49 35 0,000 0,03855758 0,04682358 GO:0042593|glucose homeostasis, ! cytosolic small ribosomal subunit GO:0022627 36 35 0,000 0,03855758 0,046808 ! maintenance of protein location GO:0045185 45 35 0,000 0,03855758 0,04679243 ! polyol metabolic process GO:0019751 46 35 0,000 0,03855758 0,04677687 ! androgen receptor signaling pathway GO:0030521 47 35 0,000 0,03855758 0,04676132 ! cytokinesis GO:0000910 38 35 0,000 0,03855758 0,04674578 ! O-acyltransferase activity GO:0008374 36 35 0,000 0,03855758 0,04673025 ! purinergic nucleotide receptor activity GO:0001614 40 36 0,000 0,03963814 0,04802389 GO:0016502|nucleotide receptor activity, ! mitochondrial respiratory chain complex I GO:0005747 37 36 0,000 0,03963814 0,04800795 GO:0030964|NADH dehydrogenase complex, GO:0045271|respiratory chain complex I, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 42 36 0,000 0,03963814 0,04799201 ! positive regulation of neurogenesis GO:0050769 38 36 0,000 0,03963814 0,04797609 ! SMAD binding GO:0046332 39 36 0,000 0,03963814 0,04796018 ! negative regulation of cell activation GO:0050866 40 36 0,000 0,03963814 0,04794427 ! inositol or phosphatidylinositol kinase activity GO:0004428 51 36 0,000 0,03963814 0,04792838 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 41 36 0,000 0,03963814 0,0479125 GO:0006956|complement activation, ! glial cell differentiation GO:0010001 38 36 0,000 0,03963814 0,04789663 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 36 0,000 0,03963814 0,04788077 ! hormone-mediated signaling GO:0009755 41 36 0,000 0,03963814 0,04786492 ! protein tyrosine/serine/threonine phosphatase activity GO:0008138 44 36 0,000 0,03963814 0,04784908 ! di-, tri-valent inorganic cation transmembrane transporter activity GO:0015082 42 36 0,000 0,03963814 0,04783326 ! carboxypeptidase activity GO:0004180 37 36 0,000 0,03963814 0,04781744 ! energy coupled proton transport, down electrochemical gradient GO:0015985 37 36 0,000 0,03963814 0,04780163 GO:0015986|ATP synthesis coupled proton transport, ! female gamete generation GO:0007292 39 36 0,000 0,03963814 0,04778583 ! maintenance of location in cell GO:0051651 38 36 0,000 0,03963814 0,04777005 ! activation of adenylate cyclase activity GO:0007190 44 37 0,000 0,04071754 0,04905469 ! regulation of hormone secretion GO:0046883 43 37 0,000 0,04071754 0,04903849 ! sugar transmembrane transporter activity GO:0051119 39 37 0,000 0,04071754 0,04902231 GO:0015144|carbohydrate transmembrane transporter activity, ! regulation of Rab protein signal transduction GO:0032483 40 37 0,000 0,04071754 0,04900614 GO:0032313|regulation of Rab GTPase activity, ! regulation of action potential in neuron GO:0019228 44 37 0,000 0,04071754 0,04898997 ! glycerol ether metabolic process GO:0006662 49 37 0,000 0,04071754 0,04897382 ! endoribonuclease activity GO:0004521 48 37 0,000 0,04071754 0,04895768 ! hindbrain development GO:0030902 43 37 0,000 0,04071754 0,04894155 ! isoprenoid metabolic process GO:0006720 41 37 0,000 0,04071754 0,04892543 ! pigmentation GO:0043473 51 37 0,000 0,04071754 0,04890932 ! regulation of neuron projection development GO:0010975 43 37 0,000 0,04071754 0,04889322 ! condensed chromosome, centromeric region GO:0000779 55 37 0,000 0,04071754 0,04887713 ! metalloexopeptidase activity GO:0008235 39 37 0,000 0,04071754 0,04886105 ! monocarboxylic acid transport GO:0015718 43 37 0,000 0,04071754 0,04884499 ! sensory perception of taste GO:0050909 37 37 0,000 0,04071754 0,04882893 ! cell junction organization GO:0034330 44 37 0,000 0,04071754 0,04881288 ! development of primary female sexual characteristics GO:0046545 40 37 0,000 0,04071754 0,04879685 GO:0046660|female sex differentiation, ! NADH dehydrogenase (ubiquinone) activity GO:0008137 38 37 0,000 0,04071754 0,04878082 GO:0050136|NADH dehydrogenase (quinone) activity, GO:0003954|NADH dehydrogenase activity, ! ion transmembrane transport GO:0034220 38 37 0,000 0,04071754 0,04876481 ! regulation of lymphocyte mediated immunity GO:0002706 43 37 0,000 0,04071754 0,0487488 ! coated pit GO:0005905 44 37 0,000 0,04071754 0,04873281 ! positive regulation of adenylate cyclase activity GO:0045762 45 38 0,000 0,04179579 0,0500069 ! regulation of translational initiation GO:0006446 50 38 0,000 0,04179579 0,04999051 ! negative regulation of binding GO:0051100 44 38 0,000 0,04179579 0,04997412 ! organic ether metabolic process GO:0018904 50 38 0,000 0,04179579 0,04995775 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 43 38 0,000 0,04179579 0,04994139 ! regulation of lymphocyte differentiation GO:0045619 51 38 0,000 0,04179579 0,04992503 ! carbon-carbon lyase activity GO:0016830 41 38 0,000 0,04179579 0,04990869 ! hydro-lyase activity GO:0016836 44 38 0,000 0,04179579 0,04989236 ! synapse organization GO:0050808 43 38 0,000 0,04179579 0,04987604 ! viral infectious cycle GO:0019058 40 38 0,000 0,04179579 0,04985973 ! phosphoinositide biosynthetic process GO:0046489 41 38 0,000 0,04179579 0,04984343 ! organic anion transport GO:0015711 42 38 0,000 0,04179579 0,04982714 ! non-membrane spanning protein tyrosine kinase activity GO:0004715 52 38 0,000 0,04179579 0,04981086 ! monosaccharide binding GO:0048029 41 38 0,000 0,04179579 0,0497946 ! development of primary male sexual characteristics GO:0046546 46 38 0,000 0,04179579 0,04977834 ! phagocytosis GO:0006909 44 38 0,000 0,04179579 0,04976209 ! regulation of ARF protein signal transduction GO:0032012 44 38 0,000 0,04179579 0,04974586 ! general RNA polymerase II transcription factor activity GO:0016251 43 38 0,000 0,04179579 0,04972963 ! DNA-directed RNA polymerase activity GO:0003899 49 38 0,000 0,04179579 0,04971342 GO:0034062|RNA polymerase activity, ! extrinsic to plasma membrane GO:0019897 43 38 0,000 0,04179579 0,04969721 ! cytosolic large ribosomal subunit GO:0022625 43 38 0,000 0,04179579 0,04968102 ! Rab GTPase activator activity GO:0005097 41 38 0,000 0,04179579 0,04966484 ! monocarboxylic acid binding GO:0033293 44 39 0,000 0,04287289 0,05092813 ! heterocycle biosynthetic process GO:0018130 51 39 0,000 0,04287289 0,05091155 ! positive regulation of DNA binding GO:0043388 53 39 0,000 0,04287289 0,05089499 ! T cell differentiation GO:0030217 64 39 0,000 0,04287289 0,05087843 ! DNA-dependent ATPase activity GO:0008094 63 39 0,000 0,04287289 0,05086188 ! cell fate specification GO:0001708 55 39 0,000 0,04287289 0,05084535 ! positive regulation of cyclase activity GO:0031281 46 39 0,000 0,04287289 0,05082883 ! regulation of adaptive immune response GO:0002819 44 39 0,000 0,04287289 0,05081231 ! regulation of cell morphogenesis involved in differentiation GO:0010769 45 39 0,000 0,04287289 0,05079581 ! receptor-mediated endocytosis GO:0006898 44 39 0,000 0,04287289 0,05077932 ! regulation of metal ion transport GO:0010959 45 39 0,000 0,04287289 0,05076284 ! energy reserve metabolic process GO:0006112 53 39 0,000 0,04287289 0,05074636 ! amine receptor activity GO:0008227 48 39 0,000 0,04287289 0,0507299 ! cytoskeleton-dependent intracellular transport GO:0030705 42 39 0,000 0,04287289 0,05071346 ! embryonic skeletal system morphogenesis GO:0048704 46 39 0,000 0,04287289 0,05069702 ! neuropeptide receptor activity GO:0008188 41 39 0,000 0,04287289 0,05068059 ! double-strand break repair GO:0006302 70 39 0,000 0,04287289 0,05066417 ! pigment metabolic process GO:0042440 43 39 0,000 0,04287289 0,05064776 ! RNA modification GO:0009451 39 39 0,000 0,04287289 0,05063137 ! damaged DNA binding GO:0003684 51 40 0,000 0,04394883 0,05188522 ! regulation of intracellular protein transport GO:0033157 43 40 0,000 0,04394883 0,05186843 ! peroxisomal membrane GO:0005778 44 40 0,000 0,04394883 0,05185166 GO:0031903|microbody membrane, ! actin filament binding GO:0051015 41 40 0,000 0,04394883 0,0518349 ! positive regulation of cell development GO:0010720 43 40 0,000 0,04394883 0,05181814 ! ribonucleoside metabolic process GO:0009119 47 40 0,000 0,04394883 0,0518014 ! biopolymer methylation GO:0043414 45 40 0,000 0,04394883 0,05178467 ! neuron migration GO:0001764 43 40 0,000 0,04394883 0,05176795 ! regulation of protein secretion GO:0050708 45 40 0,000 0,04394883 0,05175124 ! oxidoreduction coenzyme metabolic process GO:0006733 45 40 0,000 0,04394883 0,05173454 ! dorsal/ventral pattern formation GO:0009953 42 40 0,000 0,04394883 0,05171785 ! positive regulation of defense response GO:0031349 41 40 0,000 0,04394883 0,05170117 ! mammary gland development GO:0030879 47 40 0,000 0,04394883 0,0516845 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 50 40 0,000 0,04394883 0,05166785 ! neuropeptide binding GO:0042923 42 40 0,000 0,04394883 0,0516512 ! regulation of tube size GO:0035150 44 40 0,000 0,04394883 0,05163457 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 42 40 0,000 0,04394883 0,05161794 ! positive regulation of gene-specific transcription GO:0043193 46 40 0,000 0,04394883 0,05160133 ! regulation of leukocyte mediated immunity GO:0002703 46 40 0,000 0,04394883 0,05158473 ! inorganic anion transmembrane transporter activity GO:0015103 43 40 0,000 0,04394883 0,05156813 ! chromatin remodeling GO:0006338 44 40 0,000 0,04394883 0,05155155 ! solute:hydrogen symporter activity GO:0015295 44 40 0,000 0,04394883 0,05153498 ! protein amino acid N-linked glycosylation GO:0006487 46 41 0,000 0,04502362 0,05277833 ! Notch signaling pathway GO:0007219 46 41 0,000 0,04502362 0,05276138 ! keratin filament GO:0045095 44 41 0,000 0,04502362 0,05274443 ! peptide metabolic process GO:0006518 42 41 0,000 0,04502362 0,0527275 ! polysaccharide biosynthetic process GO:0000271 42 41 0,000 0,04502362 0,05271058 ! late endosome membrane GO:0031902 45 41 0,000 0,04502362 0,05269367 ! icosanoid metabolic process GO:0006690 51 41 0,000 0,04502362 0,05267677 ! positive regulation of lyase activity GO:0051349 48 41 0,000 0,04502362 0,05265988 ! integral to endoplasmic reticulum membrane GO:0030176 43 41 0,000 0,04502362 0,052643 ! glycolysis GO:0006096 43 41 0,000 0,04502362 0,05262613 ! branching morphogenesis of a tube GO:0048754 54 41 0,000 0,04502362 0,05260928 ! nucleobase, nucleoside, nucleotide kinase activity GO:0019205 51 41 0,000 0,04502362 0,05259243 ! proton-transporting two-sector ATPase complex GO:0016469 42 41 0,000 0,04502362 0,0525756 ! response to reactive oxygen species GO:0000302 49 42 0,000 0,04609726 0,0538121 ! cellular amide metabolic process GO:0043603 56 42 0,000 0,04609726 0,05379488 ! oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor GO:0016655 43 42 0,000 0,04609726 0,05377768 ! ER-Golgi intermediate compartment GO:0005793 52 42 0,000 0,04609726 0,05376049 ! regulation of multicellular organism growth GO:0040014 46 42 0,000 0,04609726 0,0537433 ! integral to Golgi membrane GO:0030173 55 42 0,000 0,04609726 0,05372613 ! nuclear export GO:0051168 46 42 0,000 0,04609726 0,05370897 ! developmental growth GO:0048589 45 42 0,000 0,04609726 0,05369183 ! structural constituent of muscle GO:0008307 46 42 0,000 0,04609726 0,05367469 ! mitochondrial transport GO:0006839 45 42 0,000 0,04609726 0,05365756 ! protein methyltransferase activity GO:0008276 49 42 0,000 0,04609726 0,05364045 ! metal cluster binding GO:0051540 47 42 0,000 0,04609726 0,05362334 GO:0051536|iron-sulfur cluster binding, ! feeding behavior GO:0007631 48 42 0,000 0,04609726 0,05360625 ! protein serine/threonine phosphatase activity GO:0004722 45 42 0,000 0,04609726 0,05358917 ! ribonucleoprotein complex assembly GO:0022618 47 42 0,000 0,04609726 0,05357209 ! positive regulation of cell cycle GO:0045787 56 43 0,000 0,04716975 0,05480103 ! RNA catabolic process GO:0006401 49 43 0,000 0,04716975 0,05478359 ! ear morphogenesis GO:0042471 56 43 0,000 0,04716975 0,05476615 ! cellular amino acid biosynthetic process GO:0008652 49 43 0,000 0,04716975 0,05474872 ! regulation of epithelial cell proliferation GO:0050678 50 43 0,000 0,04716975 0,05473131 ! cell recognition GO:0008037 51 43 0,000 0,04716975 0,05471391 ! positive regulation of cytokine production GO:0001819 46 43 0,000 0,04716975 0,05469652 ! epithelial cell differentiation GO:0030855 56 43 0,000 0,04716975 0,05467914 ! gliogenesis GO:0042063 46 43 0,000 0,04716975 0,05466177 ! endosome transport GO:0016197 48 43 0,000 0,04716975 0,05464441 ! striated muscle contraction GO:0006941 45 43 0,000 0,04716975 0,05462706 ! positive regulation of cytokine biosynthetic process GO:0042108 48 43 0,000 0,04716975 0,05460972 ! antioxidant activity GO:0016209 53 43 0,000 0,04716975 0,0545924 ! sulfur compound biosynthetic process GO:0044272 47 43 0,000 0,04716975 0,05457508 ! vascular process in circulatory system GO:0003018 48 43 0,000 0,04716975 0,05455778 ! histone modification GO:0016570 45 43 0,000 0,04716975 0,05454049 ! cellular amino acid derivative biosynthetic process GO:0042398 55 43 0,000 0,04716975 0,05452321 ! regulation of nucleocytoplasmic transport GO:0046822 46 44 0,000 0,04824109 0,0557439 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 50 44 0,000 0,04824109 0,05572625 ! negative regulation of cell migration GO:0030336 53 44 0,000 0,04824109 0,05570861 ! ATP synthesis coupled electron transport GO:0042773 45 44 0,000 0,04824109 0,05569098 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! nucleoside monophosphate biosynthetic process GO:0009124 50 44 0,000 0,04824109 0,05567336 ! chemokine activity GO:0008009 48 44 0,000 0,04824109 0,05565575 ! ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism GO:0015662 51 44 0,000 0,04824109 0,05563816 ! cartilage development GO:0051216 48 44 0,000 0,04824109 0,05562057 ! channel regulator activity GO:0016247 54 44 0,000 0,04824109 0,055603 ! excretion GO:0007588 53 44 0,000 0,04824109 0,05558544 ! male sex differentiation GO:0046661 52 44 0,000 0,04824109 0,05556789 ! protein phosphatase regulator activity GO:0019888 50 44 0,000 0,04824109 0,05555035 ! RNA elongation from RNA polymerase II promoter GO:0006368 49 44 0,000 0,04824109 0,05553282 ! amino acid activation GO:0043038 45 44 0,000 0,04824109 0,0555153 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! microbody part GO:0044438 48 44 0,000 0,04824109 0,05549779 GO:0044439|peroxisomal part, ! positive regulation of binding GO:0051099 59 45 0,000 0,04931128 0,05671108 ! solute:sodium symporter activity GO:0015370 51 45 0,000 0,04931128 0,05669321 ! transferase activity, transferring pentosyl groups GO:0016763 50 45 0,000 0,04931128 0,05667535 ! organellar ribosome GO:0000313 46 45 0,000 0,04931128 0,0566575 GO:0005761|mitochondrial ribosome, ! platelet alpha granule GO:0031091 49 45 0,000 0,04931128 0,05663966 ! single-stranded DNA binding GO:0003697 48 45 0,000 0,04931128 0,05662183 ! intrinsic to Golgi membrane GO:0031228 60 45 0,000 0,04931128 0,05660402 ! transport vesicle GO:0030133 53 45 0,000 0,04931128 0,05658621 ! regulation of endocytosis GO:0030100 52 45 0,000 0,04931128 0,05656842 ! ligase activity, forming carbon-oxygen bonds GO:0016875 47 45 0,000 0,04931128 0,05655063 GO:0016876|ligase activity, forming aminoacyl-tRNA and related compounds, GO:0004812|aminoacyl-tRNA ligase activity, ! nuclear matrix GO:0016363 56 45 0,000 0,04931128 0,05653286 ! unsaturated fatty acid metabolic process GO:0033559 55 45 0,000 0,04931128 0,0565151 ! regulation of T cell proliferation GO:0042129 53 45 0,000 0,04931128 0,05649735 ! regulation of myeloid leukocyte differentiation GO:0002761 54 45 0,000 0,04931128 0,05647961 ! DNA-dependent DNA replication GO:0006261 66 45 0,000 0,04931128 0,05646188 ! coated vesicle membrane GO:0030662 52 45 0,000 0,04931128 0,05644417 ! covalent chromatin modification GO:0016569 47 45 0,000 0,04931128 0,05642646 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 51 45 0,000 0,04931128 0,05640877 ! synaptosome GO:0019717 50 45 0,000 0,04931128 0,05639108 ! chemokine receptor binding GO:0042379 50 45 0,000 0,04931128 0,05637341 ! regulation of action potential GO:0001508 56 46 0,000 0,05038033 0,05757752 ! immunoglobulin mediated immune response GO:0016064 51 46 0,000 0,05038033 0,05755949 ! phosphatase regulator activity GO:0019208 53 46 0,000 0,05038033 0,05754147 ! regulation of inflammatory response GO:0050727 49 46 0,000 0,05038033 0,05752346 ! eye morphogenesis GO:0048592 57 46 0,000 0,05038033 0,05750546 ! regulation of JNK cascade GO:0046328 53 46 0,000 0,05038033 0,05748747 ! methylation GO:0032259 51 46 0,000 0,05038033 0,0574695 ! positive regulation of protein transport GO:0051222 50 46 0,000 0,05038033 0,05745153 ! regulation of ion transport GO:0043269 54 46 0,000 0,05038033 0,05743358 ! leukocyte migration GO:0050900 49 46 0,000 0,05038033 0,05741563 ! neuromuscular process GO:0050905 56 46 0,000 0,05038033 0,0573977 ! sulfotransferase activity GO:0008146 54 46 0,000 0,05038033 0,05737978 ! JNK cascade GO:0007254 48 46 0,000 0,05038033 0,05736187 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 54 47 0,000 0,05144823 0,05855949 ! auxiliary transport protein activity GO:0015457 58 47 0,000 0,05144823 0,05854122 ! microtubule binding GO:0008017 61 47 0,000 0,05144823 0,05852297 ! morphogenesis of a branching structure GO:0001763 70 47 0,000 0,05144823 0,05850472 ! carbon-oxygen lyase activity GO:0016835 53 47 0,000 0,05144823 0,05848649 ! viral reproductive process GO:0022415 53 47 0,000 0,05144823 0,05846827 ! RNA elongation GO:0006354 52 47 0,000 0,05144823 0,05845006 ! negative regulation of immune system process GO:0002683 58 47 0,000 0,05144823 0,05843187 ! mRNA binding GO:0003729 65 47 0,000 0,05144823 0,05841368 ! axon GO:0030424 53 48 0,000 0,05251499 0,05960631 ! protein amino acid lipidation GO:0006497 53 48 0,000 0,05251499 0,05958777 ! stress-activated protein kinase signaling pathway GO:0031098 50 48 0,000 0,05251499 0,05956924 ! proteasome complex GO:0000502 50 48 0,000 0,05251499 0,05955073 ! glutamine family amino acid metabolic process GO:0009064 62 48 0,000 0,05251499 0,05953222 ! regulation of cell projection organization GO:0031344 54 48 0,000 0,05251499 0,05951373 ! kinetochore GO:0000776 69 48 0,000 0,05251499 0,05949525 ! detection of stimulus involved in sensory perception GO:0050906 53 48 0,000 0,05251499 0,05947677 ! N-methyltransferase activity GO:0008170 53 48 0,000 0,05251499 0,05945831 ! inner ear development GO:0048839 60 48 0,000 0,05251499 0,05943987 ! excitatory extracellular ligand-gated ion channel activity GO:0005231 57 48 0,000 0,05251499 0,05942143 ! amino acid transmembrane transporter activity GO:0015171 53 48 0,000 0,05251499 0,059403 ! chromatin remodeling complex GO:0016585 54 48 0,000 0,05251499 0,05938459 ! B cell mediated immunity GO:0019724 53 48 0,000 0,05251499 0,05936619 ! steroid hormone receptor activity GO:0003707 61 48 0,000 0,05251499 0,0593478 ! regulation of cell shape GO:0008360 55 48 0,000 0,05251499 0,05932942 ! establishment of organelle localization GO:0051656 58 48 0,000 0,05251499 0,05931105 ! transferase activity, transferring alkyl or aryl (other than methyl) groups GO:0016765 52 49 0,000 0,05358061 0,06049584 ! regulation of neurotransmitter levels GO:0001505 55 49 0,000 0,05358061 0,06047712 ! oxidoreductase activity, acting on the CH-CH group of donors GO:0016627 54 49 0,000 0,05358061 0,06045842 ! response to temperature stimulus GO:0009266 57 49 0,000 0,05358061 0,06043972 ! Golgi-associated vesicle GO:0005798 59 49 0,000 0,05358061 0,06042104 ! lipid modification GO:0030258 55 49 0,000 0,05358061 0,06040237 ! synaptic vesicle GO:0008021 56 49 0,000 0,05358061 0,06038371 ! regulation of gene expression, epigenetic GO:0040029 64 49 0,000 0,05358061 0,06036506 ! pyridoxal phosphate binding GO:0030170 63 49 0,000 0,05358061 0,06034642 GO:0070279|vitamin B6 binding, ! exonuclease activity GO:0004527 79 49 0,000 0,05358061 0,0603278 ! maintenance of location GO:0051235 62 49 0,000 0,05358061 0,06030918 ! negative regulation of cell motion GO:0051271 60 49 0,000 0,05358061 0,06029058 ! nuclear periphery GO:0034399 60 49 0,000 0,05358061 0,06027199 ! regulation of muscle contraction GO:0006937 57 49 0,000 0,05358061 0,06025341 ! nucleotide-excision repair GO:0006289 53 49 0,000 0,05358061 0,06023484 ! respiratory electron transport chain GO:0022904 51 50 0,000 0,05464508 0,06141259 ! cytokine-mediated signaling pathway GO:0019221 56 50 0,000 0,05464508 0,06139367 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides GO:0016811 51 50 0,000 0,05464508 0,06137477 ! embryonic skeletal system development GO:0048706 59 50 0,000 0,05464508 0,06135588 ! glucose catabolic process GO:0006007 54 50 0,000 0,05464508 0,061337 ! aging GO:0007568 92 50 0,000 0,05464508 0,06131814 ! generation of a signal involved in cell-cell signaling GO:0003001 59 50 0,000 0,05464508 0,06129928 ! heart morphogenesis GO:0003007 57 50 0,000 0,05464508 0,06128044 ! integrin binding GO:0005178 56 50 0,000 0,05464508 0,0612616 ! detection of abiotic stimulus GO:0009582 56 50 0,000 0,05464508 0,06124278 ! regulation of angiogenesis GO:0045765 56 51 0,000 0,05570842 0,06241533 ! positive regulation of cell migration GO:0030335 63 51 0,000 0,05570842 0,06239616 ! regulation of ossification GO:0030278 59 51 0,000 0,05570842 0,06237701 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 60 51 0,000 0,05570842 0,06235787 ! positive regulation of organelle organization GO:0010638 69 51 0,000 0,05570842 0,06233874 ! cellular polysaccharide metabolic process GO:0044264 65 51 0,000 0,05570842 0,06231963 ! endocrine system development GO:0035270 55 51 0,000 0,05570842 0,06230052 ! germ cell development GO:0007281 56 51 0,000 0,05570842 0,06228143 ! transferase activity, transferring sulfur-containing groups GO:0016782 60 52 0,000 0,05677061 0,06344951 ! carbohydrate transport GO:0008643 57 52 0,000 0,05677061 0,06343007 ! ubiquitin thiolesterase activity GO:0004221 64 52 0,000 0,05677061 0,06341065 ! nucleoside monophosphate metabolic process GO:0009123 58 52 0,000 0,05677061 0,06339124 ! cell maturation GO:0048469 68 52 0,000 0,05677061 0,06337185 ! regulation of intracellular transport GO:0032386 57 52 0,000 0,05677061 0,06335246 ! vesicle organization GO:0016050 59 52 0,000 0,05677061 0,06333309 ! kidney development GO:0001822 55 52 0,000 0,05677061 0,06331372 ! cell redox homeostasis GO:0045454 57 52 0,000 0,05677061 0,06329437 ! lipoprotein biosynthetic process GO:0042158 57 52 0,000 0,05677061 0,06327504 ! lipid transporter activity GO:0005319 58 52 0,000 0,05677061 0,06325571 ! cytokine receptor activity GO:0004896 54 52 0,000 0,05677061 0,0632364 ! antiporter activity GO:0015297 53 52 0,000 0,05677061 0,06321709 ! embryonic limb morphogenesis GO:0030326 62 53 0,000 0,05783167 0,06437898 GO:0035113|embryonic appendage morphogenesis, ! glycosaminoglycan metabolic process GO:0030203 60 53 0,000 0,05783167 0,06435934 ! N-acetyltransferase activity GO:0008080 59 53 0,000 0,05783167 0,06433972 ! basement membrane GO:0005604 55 53 0,000 0,05783167 0,0643201 ! water-soluble vitamin metabolic process GO:0006767 59 53 0,000 0,05783167 0,0643005 ! negative regulation of response to stimulus GO:0048585 68 53 0,000 0,05783167 0,06428091 ! viral reproduction GO:0016032 59 53 0,000 0,05783167 0,06426133 ! chloride transport GO:0006821 60 53 0,000 0,05783167 0,06424176 ! oxygen and reactive oxygen species metabolic process GO:0006800 58 53 0,000 0,05783167 0,0642222 ! regulation of protein catabolic process GO:0042176 56 53 0,000 0,05783167 0,06420266 ! regulation of DNA replication GO:0006275 75 53 0,000 0,05783167 0,06418312 ! heterocycle catabolic process GO:0046700 56 53 0,000 0,05783167 0,0641636 ! integrin-mediated signaling pathway GO:0007229 59 53 0,000 0,05783167 0,0641441 ! single fertilization GO:0007338 58 53 0,000 0,05783167 0,0641246 ! activation of phospholipase C activity GO:0007202 61 54 0,000 0,05889159 0,06528001 GO:0010863|positive regulation of phospholipase C activity, ! double-stranded DNA binding GO:0003690 63 54 0,000 0,05889159 0,06526018 ! mitochondrial respiratory chain GO:0005746 55 54 0,000 0,05889159 0,06524036 ! nucleoside metabolic process GO:0009116 62 54 0,000 0,05889159 0,06522056 ! coated membrane GO:0048475 65 54 0,000 0,05889159 0,06520076 GO:0030117|membrane coat, ! nucleosome GO:0000786 59 54 0,000 0,05889159 0,06518098 ! cellular defense response GO:0006968 61 54 0,000 0,05889159 0,06516121 ! gastrulation GO:0007369 62 54 0,000 0,05889159 0,06514146 ! dendrite GO:0030425 60 55 0,000 0,05995037 0,0662925 ! regulation of mitosis GO:0007088 79 55 0,000 0,05995037 0,06627241 GO:0051783|regulation of nuclear division, ! positive regulation of phospholipase activity GO:0010518 62 55 0,000 0,05995037 0,06625234 ! respiratory chain GO:0070469 57 55 0,000 0,05995037 0,06623227 ! coenzyme biosynthetic process GO:0009108 68 55 0,000 0,05995037 0,06621222 ! extracellular matrix organization GO:0030198 77 55 0,000 0,05995037 0,06619218 ! positive regulation of cell motion GO:0051272 69 55 0,000 0,05995037 0,06617215 ! protein amino acid autophosphorylation GO:0046777 61 55 0,000 0,05995037 0,06615214 ! translation initiation factor activity GO:0003743 66 55 0,000 0,05995037 0,06613213 ! steroid hormone receptor signaling pathway GO:0030518 70 55 0,000 0,05995037 0,06611214 ! regulation of bone remodeling GO:0046850 64 56 0,000 0,06100803 0,06725817 ! heat shock protein binding GO:0031072 62 56 0,000 0,06100803 0,06723785 ! late endosome GO:0005770 60 56 0,000 0,06100803 0,06721754 ! regulation of phospholipase activity GO:0010517 63 56 0,000 0,06100803 0,06719725 ! sphingolipid metabolic process GO:0006665 60 56 0,000 0,06100803 0,06717696 ! intrinsic to endoplasmic reticulum membrane GO:0031227 61 56 0,000 0,06100803 0,06715669 ! ribonuclease activity GO:0004540 67 56 0,000 0,06100803 0,06713643 ! positive regulation of T cell activation GO:0050870 74 56 0,000 0,06100803 0,06711619 ! mesoderm development GO:0007498 67 56 0,000 0,06100803 0,06709595 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 61 56 0,000 0,06100803 0,06707573 ! antigen processing and presentation GO:0019882 73 56 0,000 0,06100803 0,06705552 ! proton transport GO:0015992 59 56 0,000 0,06100803 0,06703532 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 68 57 0,000 0,06206454 0,06817568 ! chromosome segregation GO:0007059 92 57 0,000 0,06206454 0,06815516 ! glycerophospholipid biosynthetic process GO:0046474 71 57 0,000 0,06206454 0,06813465 ! diacylglycerol binding GO:0019992 65 57 0,000 0,06206454 0,06811415 ! B cell activation GO:0042113 63 57 0,000 0,06206454 0,06809367 ! small ribosomal subunit GO:0015935 58 57 0,000 0,06206454 0,0680732 ! detection of external stimulus GO:0009581 64 57 0,000 0,06206454 0,06805273 ! occluding junction GO:0070160 75 58 0,000 0,06311993 0,06918915 GO:0005923|tight junction, ! hydrogen transport GO:0006818 61 58 0,000 0,06311993 0,06916837 ! lymphocyte mediated immunity GO:0002449 65 58 0,000 0,06311993 0,0691476 ! response to nutrient GO:0007584 68 58 0,000 0,06311993 0,06912684 ! large ribosomal subunit GO:0015934 64 58 0,000 0,06311993 0,06910609 ! regulation of tissue remodeling GO:0034103 66 58 0,000 0,06311993 0,06908536 ! ligand-dependent nuclear receptor activity GO:0004879 72 58 0,000 0,06311993 0,06906463 ! myosin complex GO:0016459 64 58 0,000 0,06311993 0,06904393 ! regulation of gene-specific transcription GO:0032583 69 59 0,000 0,06417418 0,07017608 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen GO:0016702 62 59 0,000 0,06417418 0,07015505 GO:0051213|dioxygenase activity, ! regulation of heart contraction GO:0008016 71 59 0,000 0,06417418 0,07013404 ! hexose catabolic process GO:0019320 64 59 0,000 0,06417418 0,07011303 ! cellular amino acid catabolic process GO:0009063 63 59 0,000 0,06417418 0,07009204 ! response to steroid hormone stimulus GO:0048545 74 59 0,000 0,06417418 0,07007106 ! cell projection assembly GO:0030031 79 59 0,000 0,06417418 0,07005009 ! regulation of cellular response to stress GO:0080135 79 59 0,000 0,06417418 0,07002914 ! appendage morphogenesis GO:0035107 68 59 0,000 0,06417418 0,0700082 GO:0035108|limb morphogenesis, ! homeostasis of number of cells GO:0048872 67 59 0,000 0,06417418 0,06998727 ! fertilization GO:0009566 65 59 0,000 0,06417418 0,06996635 ! DNA-directed RNA polymerase II, holoenzyme GO:0016591 62 59 0,000 0,06417418 0,06994545 ! Rho guanyl-nucleotide exchange factor activity GO:0005089 69 59 0,000 0,06417418 0,06992455 ! adult behavior GO:0030534 72 59 0,000 0,06417418 0,06990368 ! organelle localization GO:0051640 70 59 0,000 0,06417418 0,06988281 ! positive regulation of secretion GO:0051047 66 60 0,000 0,0652273 0,07100842 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen GO:0016701 63 60 0,000 0,0652273 0,07098723 ! phosphoinositide metabolic process GO:0030384 68 60 0,000 0,0652273 0,07096606 ! copper ion binding GO:0005507 85 60 0,000 0,0652273 0,0709449 ! positive regulation of lipase activity GO:0060193 68 60 0,000 0,0652273 0,07092376 ! activation of immune response GO:0002253 72 60 0,000 0,0652273 0,07090262 ! cell cycle checkpoint GO:0000075 91 60 0,000 0,0652273 0,0708815 ! response to metal ion GO:0010038 65 60 0,000 0,0652273 0,07086039 ! appendage development GO:0048736 69 60 0,000 0,0652273 0,0708393 GO:0060173|limb development, ! regulation of vesicle-mediated transport GO:0060627 69 60 0,000 0,0652273 0,07081822 ! secondary metabolic process GO:0019748 67 60 0,000 0,0652273 0,07079715 ! cellular hormone metabolic process GO:0034754 64 61 0,000 0,0662793 0,07191757 ! ear development GO:0043583 76 61 0,000 0,0662793 0,07189619 ! ATPase activity, coupled to transmembrane movement of ions GO:0042625 68 61 0,000 0,0662793 0,07187482 ! learning or memory GO:0007611 79 61 0,000 0,0662793 0,07185346 ! Ras GTPase binding GO:0017016 78 61 0,000 0,0662793 0,07183211 ! camera-type eye development GO:0043010 69 61 0,000 0,0662793 0,07181078 ! transcription initiation from RNA polymerase II promoter GO:0006367 69 61 0,000 0,0662793 0,07178945 ! regulation of transcription factor activity GO:0051090 80 62 0,000 0,06733017 0,07290604 GO:0090046|regulation of transcription regulator activity, ! lung development GO:0030324 90 62 0,000 0,06733017 0,07288441 ! lysosomal membrane GO:0005765 69 62 0,000 0,06733017 0,07286278 ! membrane lipid metabolic process GO:0006643 76 62 0,000 0,06733017 0,07284118 ! nuclear pore GO:0005643 79 62 0,000 0,06733017 0,07281958 ! positive regulation of protein amino acid phosphorylation GO:0001934 72 62 0,000 0,06733017 0,072798 ! transmembrane receptor protein tyrosine kinase activity GO:0004714 77 62 0,000 0,06733017 0,07277643 ! skeletal system morphogenesis GO:0048705 83 62 0,000 0,06733017 0,07275487 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 77 62 0,000 0,06733017 0,07273333 ! chloride channel activity GO:0005254 72 62 0,000 0,06733017 0,0727118 ! cell soma GO:0043025 68 62 0,000 0,06733017 0,07269028 ! microtubule motor activity GO:0003777 94 62 0,000 0,06733017 0,07266877 ! intracellular receptor-mediated signaling pathway GO:0030522 80 62 0,000 0,06733017 0,07264728 ! focal adhesion GO:0005925 72 62 0,000 0,06733017 0,0726258 ! protein maturation by peptide bond cleavage GO:0051605 69 62 0,000 0,06733017 0,07260433 ! FAD binding GO:0050660 71 63 0,000 0,06837991 0,07371451 ! urogenital system development GO:0001655 75 63 0,000 0,06837991 0,07369273 ! regulation of synaptic transmission GO:0050804 79 63 0,000 0,06837991 0,07367097 ! aminoglycan metabolic process GO:0006022 70 63 0,000 0,06837991 0,07364922 ! cAMP-mediated signaling GO:0019933 75 63 0,000 0,06837991 0,07362748 ! amine transmembrane transporter activity GO:0005275 69 63 0,000 0,06837991 0,07360575 ! regulation of immune effector process GO:0002697 81 63 0,000 0,06837991 0,07358404 ! respiratory tube development GO:0030323 92 64 0,000 0,06942852 0,07469043 ! intracellular protein transmembrane transport GO:0065002 83 64 0,000 0,06942852 0,07466841 ! tRNA processing GO:0008033 73 64 0,000 0,06942852 0,0746464 ! negative regulation of ligase activity GO:0051352 79 64 0,000 0,06942852 0,07462441 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! regulation of myeloid cell differentiation GO:0045637 77 64 0,000 0,06942852 0,07460243 ! adaptive immune response GO:0002250 70 64 0,000 0,06942852 0,07458046 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! transition metal ion transport GO:0000041 74 64 0,000 0,06942852 0,07455851 ! neurotransmitter transport GO:0006836 72 64 0,000 0,06942852 0,07453657 ! response to unfolded protein GO:0006986 66 64 0,000 0,06942852 0,07451464 ! nuclear hormone receptor binding GO:0035257 79 64 0,000 0,06942852 0,07449272 ! N-acyltransferase activity GO:0016410 70 64 0,000 0,06942852 0,07447082 ! multicellular organism reproduction GO:0032504 71 65 0,000 0,07047601 0,07557216 GO:0048609|reproductive process in a multicellular organism, ! lymphocyte differentiation GO:0030098 93 65 0,000 0,07047601 0,07554996 ! response to inorganic substance GO:0010035 71 65 0,000 0,07047601 0,07552776 ! regulation of cytokine biosynthetic process GO:0042035 84 65 0,000 0,07047601 0,07550558 ! activation of MAPK activity GO:0000187 74 65 0,000 0,07047601 0,07548341 ! gonad development GO:0008406 71 65 0,000 0,07047601 0,07546126 ! acetyltransferase activity GO:0016407 73 65 0,000 0,07047601 0,07543911 ! protein import into nucleus GO:0006606 73 66 0,000 0,07152238 0,07653671 ! developmental maturation GO:0021700 85 66 0,000 0,07152238 0,07651427 ! myeloid cell differentiation GO:0030099 78 66 0,000 0,07152238 0,07649184 ! tubulin binding GO:0015631 92 66 0,000 0,07152238 0,07646942 ! leukocyte mediated immunity GO:0002443 73 66 0,000 0,07152238 0,07644701 ! tube morphogenesis GO:0035239 84 66 0,000 0,07152238 0,07642462 ! cysteine-type endopeptidase activity GO:0004197 73 66 0,000 0,07152238 0,07640224 ! cell-substrate adherens junction GO:0005924 76 66 0,000 0,07152238 0,07637988 ! endoplasmic reticulum lumen GO:0005788 78 67 0,000 0,07256763 0,07747343 ! glycerolipid biosynthetic process GO:0045017 81 67 0,000 0,07256763 0,07745076 ! nuclear import GO:0051170 74 67 0,000 0,07256763 0,07742811 ! activation of protein kinase activity GO:0032147 83 67 0,000 0,07256763 0,07740547 ! chloride ion binding GO:0031404 79 67 0,000 0,07256763 0,07738284 ! humoral immune response GO:0006959 75 67 0,000 0,07256763 0,07736023 ! amine binding GO:0043176 77 67 0,000 0,07256763 0,07733763 ! female pregnancy GO:0007565 78 67 0,000 0,07256763 0,07731504 ! extrinsic to membrane GO:0019898 75 67 0,000 0,07256763 0,07729247 ! anion channel activity GO:0005253 77 67 0,000 0,07256763 0,07726991 ! regulation of homeostatic process GO:0032844 88 67 0,000 0,07256763 0,07724736 ! regulation of adenylate cyclase activity GO:0045761 81 68 0,000 0,07361176 0,07833596 ! amine catabolic process GO:0009310 73 68 0,000 0,07361176 0,07831312 ! monosaccharide catabolic process GO:0046365 73 68 0,000 0,07361176 0,07829029 ! cell-substrate junction GO:0030055 78 68 0,000 0,07361176 0,07826747 ! respiratory system development GO:0060541 96 68 0,000 0,07361176 0,07824466 ! mRNA transport GO:0051028 88 69 0,000 0,07465476 0,0793302 ! fatty acid biosynthetic process GO:0006633 76 69 0,000 0,07465476 0,0793071 ! small GTPase binding GO:0031267 86 69 0,000 0,07465476 0,07928401 ! regulation of transmission of nerve impulse GO:0051969 87 69 0,000 0,07465476 0,07926093 ! exocytosis GO:0006887 76 69 0,000 0,07465476 0,07923787 ! nucleosome assembly GO:0006334 87 69 0,000 0,07465476 0,07921483 ! extracellular ligand-gated ion channel activity GO:0005230 82 69 0,000 0,07465476 0,07919179 ! Ras guanyl-nucleotide exchange factor activity GO:0005088 79 69 0,000 0,07465476 0,07916877 ! amine biosynthetic process GO:0009309 78 70 0,000 0,07569665 0,08025033 ! thiolester hydrolase activity GO:0016790 84 70 0,000 0,07569665 0,08022701 ! early endosome GO:0005769 104 70 0,000 0,07569665 0,08020371 ! regulation of cyclase activity GO:0031279 83 70 0,000 0,07569665 0,08018042 ! regulation of lipase activity GO:0060191 78 70 0,000 0,07569665 0,08015715 ! amino acid transport GO:0006865 76 70 0,000 0,07569665 0,08013389 ! chromatin assembly GO:0031497 88 70 0,000 0,07569665 0,08011064 ! hormone receptor binding GO:0051427 85 70 0,000 0,07569665 0,08008741 ! positive regulation of phosphorylation GO:0042327 82 70 0,000 0,07569665 0,08006419 ! calcium channel activity GO:0005262 86 70 0,000 0,07569665 0,08004098 ! response to protein stimulus GO:0051789 73 70 0,000 0,07569665 0,08001779 ! axon guidance GO:0007411 87 70 0,000 0,07569665 0,07999461 ! nuclear chromosome part GO:0044454 94 70 0,000 0,07569665 0,07997144 ! oxidoreductase activity, acting on NADH or NADPH GO:0016651 73 71 0,000 0,07673742 0,08104751 ! protein localization in nucleus GO:0034504 78 71 0,000 0,07673742 0,08102405 ! lipoprotein metabolic process GO:0042157 76 71 0,000 0,07673742 0,08100061 ! positive regulation of phosphorus metabolic process GO:0010562 85 72 0,000 0,07777707 0,08207427 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 84 72 0,000 0,07777707 0,08205054 ! steroid biosynthetic process GO:0006694 83 72 0,000 0,07777707 0,08202682 ! regulation of MAPKKK cascade GO:0043408 82 72 0,000 0,07777707 0,08200311 ! regulation of lyase activity GO:0051339 85 72 0,000 0,07777707 0,08197942 ! acute inflammatory response GO:0002526 91 72 0,000 0,07777707 0,08195574 ! apical junction complex GO:0043296 90 72 0,000 0,07777707 0,08193207 ! phospholipase activity GO:0004620 99 72 0,000 0,07777707 0,08190842 ! membrane raft GO:0045121 81 72 0,000 0,07777707 0,08188478 ! regulation of neurological system process GO:0031644 91 72 0,000 0,07777707 0,08186116 ! elevation of cytosolic calcium ion concentration GO:0007204 87 73 0,000 0,07881561 0,0829303 GO:0051480|cytosolic calcium ion homeostasis, ! response to drug GO:0042493 94 73 0,000 0,07881561 0,08290639 ! protein transporter activity GO:0008565 80 73 0,000 0,07881561 0,08288249 ! regulation of cAMP biosynthetic process GO:0030817 86 73 0,000 0,07881561 0,0828586 ! exopeptidase activity GO:0008238 81 73 0,000 0,07881561 0,08283473 ! digestion GO:0007586 81 73 0,000 0,07881561 0,08281088 ! regulation of Rho protein signal transduction GO:0035023 88 73 0,000 0,07881561 0,08278703 ! cell-matrix adhesion GO:0007160 102 74 0,000 0,07985304 0,08385259 ! response to oxygen levels GO:0070482 86 74 0,000 0,07985304 0,08382846 ! potassium channel complex GO:0034705 84 74 0,000 0,07985304 0,08380434 GO:0008076|voltage-gated potassium channel complex, ! GTPase binding GO:0051020 91 74 0,000 0,07985304 0,08378024 ! protein-DNA complex assembly GO:0065004 101 74 0,000 0,07985304 0,08375615 ! hydrolase activity, hydrolyzing O-glycosyl compounds GO:0004553 85 74 0,000 0,07985304 0,08373207 ! one-carbon metabolic process GO:0006730 84 74 0,000 0,07985304 0,08370801 ! blood coagulation GO:0007596 90 74 0,000 0,07985304 0,08368397 GO:0050817|coagulation, ! reproductive structure development GO:0048608 89 74 0,000 0,07985304 0,08365993 ! apicolateral plasma membrane GO:0016327 92 74 0,000 0,07985304 0,08363591 ! phosphoinositide-mediated signaling GO:0048015 92 74 0,000 0,07985304 0,08361191 ! cellular lipid catabolic process GO:0044242 99 74 0,000 0,07985304 0,08358792 ! ubiquitin ligase complex GO:0000151 91 74 0,000 0,07985304 0,08356394 ! cell projection part GO:0044463 80 74 0,000 0,07985304 0,08353997 ! meiosis GO:0007126 108 75 0,000 0,08088935 0,08459987 GO:0051327|M phase of meiotic cell cycle, ! regulation of DNA binding GO:0051101 94 75 0,000 0,08088935 0,08457563 ! carboxylic acid transmembrane transporter activity GO:0046943 85 75 0,000 0,08088935 0,08455139 ! regulation of cell cycle process GO:0010564 113 75 0,000 0,08088935 0,08452717 ! regulation of cAMP metabolic process GO:0030814 88 75 0,000 0,08088935 0,08450297 ! regulation of blood pressure GO:0008217 82 75 0,000 0,08088935 0,08447877 ! transcription initiation GO:0006352 84 75 0,000 0,08088935 0,0844546 ! Ras GTPase activator activity GO:0005099 83 75 0,000 0,08088935 0,08443043 ! defense response to bacterium GO:0042742 81 76 0,000 0,08192455 0,08548649 ! regulation of lipid metabolic process GO:0019216 98 76 0,000 0,08192455 0,08546204 ! meiotic cell cycle GO:0051321 109 76 0,000 0,08192455 0,08543761 ! regulation of neuron differentiation GO:0045664 96 76 0,000 0,08192455 0,08541319 ! condensed chromosome GO:0000793 106 76 0,000 0,08192455 0,08538879 ! protein-DNA complex GO:0032993 93 76 0,000 0,08192455 0,0853644 ! organic acid transmembrane transporter activity GO:0005342 86 76 0,000 0,08192455 0,08534003 ! development of primary sexual characteristics GO:0045137 86 76 0,000 0,08192455 0,08531566 ! cytosolic ribosome GO:0022626 82 76 0,000 0,08192455 0,08529132 ! serine-type endopeptidase inhibitor activity GO:0004867 93 76 0,000 0,08192455 0,08526698 ! S-adenosylmethionine-dependent methyltransferase activity GO:0008757 84 77 0,000 0,08295864 0,08631863 ! nucleosome organization GO:0034728 96 77 0,000 0,08295864 0,08629402 ! alcohol catabolic process GO:0046164 84 77 0,000 0,08295864 0,08626942 ! vacuolar membrane GO:0005774 86 77 0,000 0,08295864 0,08624484 ! G-protein-coupled receptor binding GO:0001664 87 77 0,000 0,08295864 0,08622027 ! regulation of Ras GTPase activity GO:0032318 88 77 0,000 0,08295864 0,08619571 ! establishment of RNA localization GO:0051236 97 77 0,000 0,08295864 0,08617117 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! phosphoric diester hydrolase activity GO:0008081 99 78 0,000 0,08399162 0,08721931 ! endonuclease activity GO:0004519 111 78 0,000 0,08399162 0,08719449 ! cofactor biosynthetic process GO:0051188 93 78 0,000 0,08399162 0,08716969 ! inorganic anion transport GO:0015698 87 78 0,000 0,08399162 0,08714489 ! regulation of protein transport GO:0051223 85 78 0,000 0,08399162 0,08712012 ! regulation of nucleotide biosynthetic process GO:0030808 91 78 0,000 0,08399162 0,08709535 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! positive regulation of protein modification process GO:0031401 100 78 0,000 0,08399162 0,0870706 ! transmembrane receptor protein kinase activity GO:0019199 95 78 0,000 0,08399162 0,08704587 ! carboxylesterase activity GO:0004091 93 78 0,000 0,08399162 0,08702114 ! protein ubiquitination GO:0016567 95 78 0,000 0,08399162 0,08699644 ! extracellular matrix structural constituent GO:0005201 96 78 0,000 0,08399162 0,08697174 ! RNA localization GO:0006403 99 79 0,000 0,0850235 0,08801524 ! positive regulation of MAP kinase activity GO:0043406 89 79 0,000 0,0850235 0,08799028 ! vitamin metabolic process GO:0006766 86 79 0,000 0,0850235 0,08796532 ! T cell activation GO:0042110 120 79 0,000 0,0850235 0,08794038 ! phosphoinositide binding GO:0035091 99 79 0,000 0,0850235 0,08791545 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 88 80 0,000 0,08605426 0,08895607 ! eye development GO:0001654 93 80 0,000 0,08605426 0,08893086 ! ATP biosynthetic process GO:0006754 89 80 0,000 0,08605426 0,08890568 ! rhythmic process GO:0048511 90 80 0,000 0,08605426 0,08888051 ! regulation of catabolic process GO:0009894 87 80 0,000 0,08605426 0,08885535 ! SH3 domain binding GO:0017124 95 80 0,000 0,08605426 0,08883021 ! hemostasis GO:0007599 96 80 0,000 0,08605426 0,08880508 ! chromosome, centromeric region GO:0000775 119 80 0,000 0,08605426 0,08877996 ! regulation of cyclic nucleotide metabolic process GO:0030799 93 80 0,000 0,08605426 0,08875486 ! cell-substrate adhesion GO:0031589 109 80 0,000 0,08605426 0,08872978 ! rRNA processing GO:0006364 84 80 0,000 0,08605426 0,08870471 ! cholesterol metabolic process GO:0008203 91 81 0,000 0,08708392 0,08974072 ! vacuolar part GO:0044437 91 81 0,000 0,08708392 0,08971538 ! ossification GO:0001503 111 82 0,000 0,08811248 0,09074938 ! biogenic amine metabolic process GO:0006576 99 82 0,000 0,08811248 0,09072377 ! forebrain development GO:0030900 93 82 0,000 0,08811248 0,09069817 ! external side of plasma membrane GO:0009897 105 82 0,000 0,08811248 0,09067259 ! heparin binding GO:0008201 108 82 0,000 0,08811248 0,09064702 ! microtubule-based movement GO:0007018 119 83 0,000 0,08913993 0,09167817 ! nuclear speck GO:0016607 99 83 0,000 0,08913993 0,09165233 ! rRNA metabolic process GO:0016072 88 83 0,000 0,08913993 0,0916265 ! ATP-dependent helicase activity GO:0008026 107 83 0,000 0,08913993 0,09160069 GO:0070035|purine NTP-dependent helicase activity, ! regulation of cell adhesion GO:0030155 98 83 0,000 0,08913993 0,0915749 ! regulation of T cell activation GO:0050863 104 83 0,000 0,08913993 0,09154912 ! regulation of establishment of protein localization GO:0070201 90 83 0,000 0,08913993 0,09152335 ! oxidative phosphorylation GO:0006119 85 83 0,000 0,08913993 0,0914976 ! bone development GO:0060348 112 83 0,000 0,08913993 0,09147186 ! regulation of nucleotide metabolic process GO:0006140 96 83 0,000 0,08913993 0,09144614 ! cilium GO:0005929 88 83 0,000 0,08913993 0,09142043 ! regulation of DNA metabolic process GO:0051052 139 84 0,000 0,09016628 0,09244704 ! regulation of defense response GO:0031347 98 84 0,000 0,09016628 0,09242107 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 94 84 0,000 0,09016628 0,09239511 ! nitrogen compound catabolic process GO:0044270 91 84 0,000 0,09016628 0,09236916 ! DNA recombination GO:0006310 147 84 0,000 0,09016628 0,09234323 ! phospholipid biosynthetic process GO:0008654 101 85 0,000 0,09119153 0,09336702 ! protein modification by small protein conjugation GO:0032446 103 85 0,000 0,09119153 0,09334082 ! monooxygenase activity GO:0004497 92 85 0,000 0,09119153 0,09331464 ! hydrogen ion transmembrane transporter activity GO:0015078 88 85 0,000 0,09119153 0,09328847 ! negative regulation of transport GO:0051051 98 86 0,000 0,09221567 0,09430972 ! clathrin-coated vesicle GO:0030136 100 86 0,000 0,09221567 0,09428329 ! Golgi vesicle transport GO:0048193 98 86 0,000 0,09221567 0,09425687 ! lipase activity GO:0016298 114 86 0,000 0,09221567 0,09423047 ! voltage-gated potassium channel activity GO:0005249 105 86 0,000 0,09221567 0,09420408 ! adherens junction GO:0005912 100 86 0,000 0,09221567 0,09417771 ! microtubule cytoskeleton organization GO:0000226 113 87 0,000 0,09323872 0,09519587 ! leukocyte differentiation GO:0002521 118 87 0,000 0,09323872 0,09516924 ! pigment granule GO:0048770 101 87 0,000 0,09323872 0,09514262 GO:0042470|melanosome, ! regulation of cell morphogenesis GO:0022604 100 87 0,000 0,09323872 0,09511601 ! carbohydrate biosynthetic process GO:0016051 95 88 0,000 0,09426067 0,09613165 ! growth factor binding GO:0019838 102 88 0,000 0,09426067 0,09610479 ! protein processing GO:0016485 100 88 0,000 0,09426067 0,09607793 ! protein tyrosine phosphatase activity GO:0004725 109 89 0,000 0,09528152 0,09709134 ! protein kinase binding GO:0019901 115 89 0,000 0,09528152 0,09706423 ! gland development GO:0048732 108 89 0,000 0,09528152 0,09703713 ! ATP metabolic process GO:0046034 100 90 0,000 0,09630128 0,0980483 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 101 90 0,000 0,09630128 0,09802095 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! peroxisome GO:0005777 100 90 0,000 0,09630128 0,0979936 GO:0042579|microbody, ! glycerophospholipid metabolic process GO:0006650 109 90 0,000 0,09630128 0,09796628 ! sterol metabolic process GO:0016125 102 90 0,000 0,09630128 0,09793896 ! negative regulation of multicellular organismal process GO:0051241 102 90 0,000 0,09630128 0,09791167 ! anion binding GO:0043168 104 90 0,000 0,09630128 0,09788439 ! amine transport GO:0015837 97 90 0,000 0,09630128 0,09785712 ! response to virus GO:0009615 109 90 0,000 0,09630128 0,09782987 ! extracellular matrix part GO:0044420 111 90 0,000 0,09630128 0,09780264 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 108 91 0,000 0,09731994 0,09880967 ! ribonucleoside triphosphate biosynthetic process GO:0009201 102 91 0,000 0,09731994 0,09878218 GO:0009142|nucleoside triphosphate biosynthetic process, ! positive regulation of immune response GO:0050778 104 91 0,000 0,09731994 0,0987547 ! sulfur metabolic process GO:0006790 98 91 0,000 0,09731994 0,09872724 ! sex differentiation GO:0007548 103 91 0,000 0,09731994 0,09869979 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 112 91 0,000 0,09731994 0,09867236 ! hormone metabolic process GO:0042445 107 91 0,000 0,09731994 0,09864494 ! regulation of protein localization GO:0032880 99 91 0,000 0,09731994 0,09861754 ! detection of stimulus GO:0051606 100 91 0,000 0,09731994 0,09859015 ! structure-specific DNA binding GO:0043566 112 92 0,000 0,09833751 0,09959335 ! anatomical structure homeostasis GO:0060249 121 92 0,000 0,09833751 0,09956571 ! carboxylic acid catabolic process GO:0046395 100 92 0,000 0,09833751 0,09953808 GO:0016054|organic acid catabolic process, ! translation factor activity, nucleic acid binding GO:0008135 108 92 0,000 0,09833751 0,09951047 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 111 92 0,000 0,09833751 0,09948287 ! regulation of GTPase activity GO:0043087 105 92 0,000 0,09833751 0,09945529 ! extracellular structure organization GO:0043062 119 92 0,000 0,09833751 0,09942773 ! protein import GO:0017038 102 93 0,000 0,09935399 0,10042764 ! neurotransmitter receptor activity GO:0030594 104 93 0,000 0,09935399 0,10039982 ! response to nutrient levels GO:0031667 105 93 0,000 0,09935399 0,10037201 ! protein modification by small protein conjugation or removal GO:0070647 112 93 0,000 0,09935399 0,10034422 ! ATPase activity, coupled to transmembrane movement of substances GO:0042626 102 94 0,000 0,10036937 0,10134167 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0016616 104 94 0,000 0,10036937 0,10131363 ! morphogenesis of an epithelium GO:0002009 113 94 0,000 0,10036937 0,10128561 GO:0060429|epithelium development, ! anchoring junction GO:0070161 108 94 0,000 0,10036937 0,10125759 ! neurotransmitter binding GO:0042165 105 94 0,000 0,10036937 0,1012296 ! DNA packaging GO:0006323 113 94 0,000 0,10036937 0,10120162 ! ATPase activity, coupled to movement of substances GO:0043492 104 95 0,000 0,10138366 0,10219608 ! anterior/posterior pattern formation GO:0009952 109 95 0,000 0,10138366 0,10216785 ! protein localization in organelle GO:0033365 104 95 0,000 0,10138366 0,10213963 ! Wnt receptor signaling pathway GO:0016055 121 95 0,000 0,10138366 0,10211143 ! immune effector process GO:0002252 110 95 0,000 0,10138366 0,10208325 ! apical plasma membrane GO:0016324 105 95 0,000 0,10138366 0,10205508 ! translational elongation GO:0006414 104 96 0,000 0,10239687 0,10304656 ! hydrolase activity, acting on glycosyl bonds GO:0016798 109 96 0,000 0,10239687 0,10301814 ! in utero embryonic development GO:0001701 110 96 0,000 0,10239687 0,10298974 ! carbohydrate catabolic process GO:0016052 116 96 0,000 0,10239687 0,10296135 ! receptor complex GO:0043235 131 96 0,000 0,10239687 0,10293298 ! regulation of response to external stimulus GO:0032101 109 96 0,000 0,10239687 0,10290462 ! monovalent inorganic cation transmembrane transporter activity GO:0015077 100 96 0,000 0,10239687 0,10287628 ! electron transport chain GO:0022900 104 97 0,000 0,10340899 0,10386453 ! microtubule associated complex GO:0005875 135 97 0,000 0,10340899 0,10383594 ! metalloendopeptidase activity GO:0004222 126 97 0,000 0,10340899 0,10380737 ! perinuclear region of cytoplasm GO:0048471 125 97 0,000 0,10340899 0,10377881 ! hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances GO:0016820 105 97 0,000 0,10340899 0,10375027 ! carboxylic acid binding GO:0031406 108 97 0,000 0,10340899 0,10372174 ! protein maturation GO:0051604 109 97 0,000 0,10340899 0,10369323 ! intermediate filament GO:0005882 102 98 0,000 0,10442002 0,10467827 GO:0045111|intermediate filament cytoskeleton, ! UDP-glycosyltransferase activity GO:0008194 120 98 0,000 0,10442002 0,10464951 ! cell fate commitment GO:0045165 118 98 0,000 0,10442002 0,10462077 ! hormone activity GO:0005179 113 99 0,000 0,10542996 0,10560365 ! solute:cation symporter activity GO:0015294 110 99 0,000 0,10542996 0,10557466 ! unfolded protein binding GO:0051082 118 100 0,000 0,10643882 0,10655566 ! nuclear chromosome GO:0000228 127 100 0,000 0,10643882 0,10652642 ! regulation of neurogenesis GO:0050767 123 100 0,000 0,10643882 0,10649721 ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds GO:0016810 105 100 0,000 0,10643882 0,10646801 ! peptide receptor activity, G-protein coupled GO:0008528 107 100 0,000 0,10643882 0,10643882