Study Desmedt-ER-neg
Study informations
165 subnetworks in total page | file
2310 genes associated page | file
Enriched GO terms page
General informations
General Index page
Study Index page
Subnetwork 6725
score
| Dataset | Score | P-val 1 | P-val 2 | P-val 3 | Fisher Score |
|---|
| IPC | 0.7509 | 3.704e-03 | 6.120e-04 | 7.780e-01 | 1.764e-06 |
|---|
| Loi | 0.2312 | 7.891e-02 | 1.101e-02 | 4.249e-01 | 3.691e-04 |
|---|
| Schmidt | 0.6745 | 0.000e+00 | 0.000e+00 | 4.374e-02 | 0.000e+00 |
|---|
| VanDeVijver | 0.7910 | 0.000e+00 | 0.000e+00 | 3.436e-03 | 0.000e+00 |
|---|
| Wang | 0.2629 | 2.502e-03 | 4.218e-02 | 3.886e-01 | 4.102e-05 |
|---|
Expression data for subnetwork 6725 in each dataset
IPC |
Loi |
Schmidt |
VanDeVijver |
Wang |
Subnetwork structure for each dataset
- IPC
Score for each gene in subnetwork 6725 in each dataset
| Gene Symbol | Links | Frequency | Frequency Rank | Subnetwork score rank | Global rank |
IPC | Loi | Schmidt | VanDeVijver | Wang |
|---|
| EP300 |   | 113 | 4 | 1 | 4 | -0.149 | 0.087 | 0.102 | 0.052 | 0.025 |
|---|
| CCNC | | 5 | 360 | 570 | 562 | 0.085 | -0.053 | undef | 0.028 | undef |
|---|
| PAX6 | | 22 | 69 | 318 | 312 | 0.259 | -0.003 | 0.112 | undef | 0.168 |
|---|
| PSMA2 | | 1 | 1195 | 1396 | 1423 | 0.199 | 0.001 | -0.102 | -0.060 | -0.080 |
|---|
| POLR1A | | 6 | 301 | 457 | 452 | -0.193 | -0.066 | undef | 0.093 | undef |
|---|
| EGF | | 12 | 140 | 638 | 620 | -0.212 | 0.182 | -0.276 | -0.060 | 0.005 |
|---|
| SLC2A1 | | 7 | 256 | 236 | 237 | 0.205 | 0.143 | -0.050 | -0.023 | 0.086 |
|---|
| ERBB2 | | 141 | 1 | 1 | 1 | -0.103 | 0.092 | -0.090 | 0.267 | 0.046 |
|---|
| GIPC1 | | 4 | 440 | 1396 | 1379 | 0.185 | 0.124 | -0.045 | -0.095 | 0.006 |
|---|
| COL11A1 | | 3 | 557 | 525 | 540 | 0.191 | 0.149 | -0.023 | undef | 0.309 |
|---|
| PRKCA | | 63 | 15 | 1 | 10 | -0.016 | -0.088 | 0.174 | 0.095 | 0.005 |
|---|
| FABP7 | | 1 | 1195 | 1396 | 1423 | -0.324 | 0.146 | -0.084 | -0.150 | -0.098 |
|---|
| CDH9 | | 2 | 743 | 1396 | 1391 | undef | -0.013 | 0.162 | 0.199 | 0.193 |
|---|
| CDH1 | | 37 | 32 | 296 | 278 | -0.227 | 0.187 | -0.236 | 0.137 | -0.024 |
|---|
| CTNNB1 | | 43 | 25 | 83 | 81 | -0.113 | 0.187 | 0.159 | -0.090 | 0.239 |
|---|
| VTN | | 1 | 1195 | 1396 | 1423 | -0.113 | -0.048 | 0.000 | 0.044 | 0.153 |
|---|
| COL5A1 | | 2 | 743 | 1141 | 1144 | 0.016 | 0.226 | 0.006 | 0.075 | 0.201 |
|---|
| SRRM2 | | 2 | 743 | 1396 | 1391 | -0.054 | 0.101 | -0.080 | 0.024 | 0.111 |
|---|
| SOX11 | | 5 | 360 | 1396 | 1378 | -0.039 | -0.073 | -0.028 | 0.274 | -0.104 |
|---|
| COPS8 | | 1 | 1195 | 1396 | 1423 | -0.003 | -0.065 | -0.051 | 0.147 | 0.153 |
|---|
| SMAD9 | | 9 | 196 | 296 | 285 | -0.090 | -0.153 | 0.055 | 0.081 | -0.059 |
|---|
| TGFA | | 3 | 557 | 1396 | 1382 | -0.057 | -0.027 | -0.158 | -0.216 | 0.020 |
|---|
| POLR2D | | 1 | 1195 | 1396 | 1423 | 0.120 | -0.072 | 0.109 | -0.005 | 0.034 |
|---|
| LRP5 | | 3 | 557 | 1141 | 1129 | -0.129 | -0.051 | 0.011 | 0.017 | -0.146 |
|---|
| AURKB | | 4 | 440 | 83 | 112 | 0.179 | -0.189 | 0.086 | -0.058 | -0.028 |
|---|
| VEGFA | | 68 | 14 | 83 | 78 | 0.090 | 0.200 | 0.030 | 0.095 | 0.148 |
|---|
| CDK1 | | 63 | 15 | 83 | 79 | 0.265 | -0.195 | 0.106 | 0.088 | 0.031 |
|---|
| ADM | | 10 | 167 | 682 | 653 | 0.255 | 0.187 | 0.091 | 0.169 | 0.212 |
|---|
| YWHAG | | 24 | 62 | 296 | 279 | 0.067 | 0.024 | undef | 0.266 | undef |
|---|
| FZD7 | | 2 | 743 | 1396 | 1391 | -0.219 | 0.062 | 0.062 | -0.110 | -0.059 |
|---|
| RBL1 | | 21 | 73 | 1 | 27 | 0.078 | undef | undef | 0.051 | undef |
|---|
| KLF5 | | 76 | 9 | 1 | 7 | 0.077 | 0.117 | -0.007 | -0.110 | -0.006 |
|---|
| SERPINE1 | | 8 | 222 | 179 | 200 | 0.160 | 0.200 | 0.056 | 0.070 | 0.030 |
|---|
| POLR2H | | 2 | 743 | 1364 | 1363 | 0.255 | -0.016 | 0.147 | undef | 0.108 |
|---|
| COPS6 | | 16 | 104 | 1 | 31 | 0.147 | -0.068 | 0.128 | 0.216 | 0.065 |
|---|
| NRP1 | | 8 | 222 | 1222 | 1186 | -0.043 | 0.025 | 0.201 | 0.029 | 0.071 |
|---|
| ARRB2 | | 2 | 743 | 1396 | 1391 | -0.064 | -0.239 | -0.017 | undef | -0.189 |
|---|
| FOSL1 | | 11 | 148 | 366 | 360 | -0.040 | 0.164 | 0.010 | 0.128 | 0.005 |
|---|
| ARNT | | 4 | 440 | 1203 | 1184 | 0.221 | -0.023 | 0.140 | 0.122 | -0.124 |
|---|
| POU3F2 | | 17 | 95 | 928 | 891 | 0.135 | 0.114 | 0.155 | 0.253 | 0.040 |
|---|
| PLSCR4 | | 13 | 124 | 318 | 316 | -0.069 | 0.140 | 0.231 | 0.212 | 0.212 |
|---|
| TFF3 | | 2 | 743 | 1396 | 1391 | 0.029 | 0.070 | -0.026 | 0.098 | -0.093 |
|---|
| TGFB2 | | 7 | 256 | 525 | 515 | -0.063 | 0.244 | 0.226 | 0.079 | 0.015 |
|---|
| KLHL8 | | 1 | 1195 | 1396 | 1423 | -0.176 | 0.079 | undef | 0.103 | undef |
|---|
| RSRC1 | | 21 | 73 | 366 | 354 | 0.023 | 0.104 | 0.105 | -0.098 | 0.212 |
|---|
| HOXB2 | | 33 | 37 | 318 | 289 | 0.024 | -0.143 | 0.076 | 0.247 | -0.184 |
|---|
| THBS1 | | 5 | 360 | 1141 | 1109 | 0.078 | 0.044 | 0.185 | 0.200 | 0.267 |
|---|
| RASSF8 | | 5 | 360 | 296 | 310 | -0.078 | 0.121 | 0.174 | 0.114 | -0.092 |
|---|
| MED10 | | 3 | 557 | 1165 | 1151 | 0.062 | -0.149 | undef | undef | undef |
|---|
| MYC | | 72 | 10 | 1 | 8 | -0.101 | -0.169 | 0.188 | undef | -0.134 |
|---|
| WT1 | | 33 | 37 | 1 | 21 | 0.254 | -0.039 | 0.036 | undef | 0.172 |
|---|
| SPTAN1 | | 2 | 743 | 1364 | 1363 | -0.074 | 0.035 | 0.077 | 0.067 | -0.025 |
|---|
| MYB | | 28 | 47 | 366 | 344 | -0.028 | 0.075 | 0.002 | 0.065 | -0.012 |
|---|
| PSMB4 | | 2 | 743 | 983 | 988 | 0.281 | -0.082 | -0.027 | -0.147 | -0.066 |
|---|
| PIK3R1 | | 127 | 2 | 1 | 2 | -0.237 | 0.381 | 0.065 | undef | -0.002 |
|---|
| EDN1 | | 6 | 301 | 682 | 669 | 0.100 | 0.126 | 0.249 | -0.086 | 0.121 |
|---|
| PSMD4 | | 11 | 148 | 296 | 282 | 0.285 | -0.243 | -0.043 | 0.087 | -0.045 |
|---|
| FANCA | | 9 | 196 | 1 | 44 | 0.120 | -0.188 | 0.106 | -0.127 | -0.053 |
|---|
| EGFR | | 117 | 3 | 1 | 3 | -0.195 | 0.240 | -0.205 | -0.187 | 0.065 |
|---|
| CDK5R1 | | 17 | 95 | 552 | 521 | -0.150 | 0.038 | -0.096 | 0.121 | 0.091 |
|---|
| DKK1 | | 4 | 440 | 236 | 262 | 0.134 | 0.091 | -0.124 | 0.065 | 0.129 |
|---|
| IGFBP5 | | 48 | 23 | 83 | 80 | -0.076 | 0.110 | 0.074 | 0.278 | 0.181 |
|---|
| GRB7 | | 58 | 18 | 1 | 12 | 0.021 | 0.115 | -0.072 | 0.229 | 0.129 |
|---|
| POLR2E | | 2 | 743 | 1396 | 1391 | 0.127 | 0.039 | 0.166 | 0.084 | -0.018 |
|---|
| ARRB1 | | 1 | 1195 | 1396 | 1423 | -0.008 | -0.137 | -0.173 | -0.132 | -0.116 |
|---|
| SHROOM2 | | 3 | 557 | 1396 | 1382 | 0.080 | 0.059 | -0.174 | 0.142 | -0.105 |
|---|
| HEXA | | 3 | 557 | 1141 | 1129 | 0.131 | -0.121 | 0.091 | -0.031 | -0.144 |
|---|
| AHR | | 8 | 222 | 478 | 461 | 0.180 | 0.067 | 0.091 | -0.182 | -0.129 |
|---|
| IGF2 | | 14 | 117 | 570 | 553 | -0.022 | 0.172 | 0.145 | 0.087 | 0.116 |
|---|
| DNAJA2 | | 3 | 557 | 780 | 781 | 0.054 | 0.063 | -0.152 | -0.019 | 0.081 |
|---|
GO Enrichment output for subnetwork 6725 in each dataset
| Name | Accession Number | Link | P-val | Corrected P-val |
|---|
| anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | GO:0031145 |  | 2.205E-09 | 5.386E-06 |
|---|
| positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle | GO:0051437 | | 2.483E-09 | 3.033E-06 |
|---|
| positive regulation of ubiquitin-protein ligase activity | GO:0051443 | | 3.509E-09 | 2.857E-06 |
|---|
| regulation of ubiquitin-protein ligase activity during mitotic cell cycle | GO:0051439 | | 3.509E-09 | 2.143E-06 |
|---|
| positive regulation of ligase activity | GO:0051351 | | 6.036E-09 | 2.949E-06 |
|---|
| regulation of ubiquitin-protein ligase activity | GO:0051438 | | 7.42E-09 | 3.021E-06 |
|---|
| regulation of ligase activity | GO:0051340 | | 1.213E-08 | 4.234E-06 |
|---|
| neutrophil chemotaxis | GO:0030593 | | 1.908E-08 | 5.825E-06 |
|---|
| proteasomal ubiquitin-dependent protein catabolic process | GO:0043161 | | 2.726E-08 | 7.4E-06 |
|---|
| positive regulation of endothelial cell migration | GO:0010595 | | 4.481E-08 | 1.095E-05 |
|---|
| phosphoinositide 3-kinase cascade | GO:0014065 | | 4.481E-08 | 9.952E-06 |
|---|
| Name | Accession Number | Link | P-val | Corrected P-val |
|---|
| anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | GO:0031145 | | 3.475E-09 | 8.361E-06 |
|---|
| positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle | GO:0051437 | | 3.913E-09 | 4.707E-06 |
|---|
| positive regulation of ubiquitin-protein ligase activity | GO:0051443 | | 5.525E-09 | 4.431E-06 |
|---|
| regulation of ubiquitin-protein ligase activity during mitotic cell cycle | GO:0051439 | | 5.525E-09 | 3.323E-06 |
|---|
| positive regulation of ligase activity | GO:0051351 | | 9.493E-09 | 4.568E-06 |
|---|
| regulation of ubiquitin-protein ligase activity | GO:0051438 | | 1.166E-08 | 4.677E-06 |
|---|
| regulation of ligase activity | GO:0051340 | | 1.905E-08 | 6.547E-06 |
|---|
| neutrophil chemotaxis | GO:0030593 | | 2.564E-08 | 7.71E-06 |
|---|
| proteasomal ubiquitin-dependent protein catabolic process | GO:0043161 | | 4.27E-08 | 1.142E-05 |
|---|
| positive regulation of endothelial cell migration | GO:0010595 | | 5.692E-08 | 1.369E-05 |
|---|
| phosphoinositide 3-kinase cascade | GO:0014065 | | 5.692E-08 | 1.245E-05 |
|---|
| Name | Accession Number | Link | P-val | Corrected P-val |
|---|
| anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | GO:0031145 | | 1.325E-08 | 3.047E-05 |
|---|
| positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle | GO:0051437 | | 1.512E-08 | 1.738E-05 |
|---|
| positive regulation of ubiquitin-protein ligase activity | GO:0051443 | | 2.216E-08 | 1.699E-05 |
|---|
| regulation of ubiquitin-protein ligase activity during mitotic cell cycle | GO:0051439 | | 2.216E-08 | 1.274E-05 |
|---|
| angiogenesis | GO:0001525 | | 2.94E-08 | 1.352E-05 |
|---|
| regulation of response to external stimulus | GO:0032101 | | 3.224E-08 | 1.236E-05 |
|---|
| positive regulation of ligase activity | GO:0051351 | | 3.583E-08 | 1.177E-05 |
|---|
| negative regulation of cellular protein metabolic process | GO:0032269 | | 4.227E-08 | 1.215E-05 |
|---|
| regulation of ubiquitin-protein ligase activity | GO:0051438 | | 4.504E-08 | 1.151E-05 |
|---|
| regulation of ligase activity | GO:0051340 | | 6.971E-08 | 1.603E-05 |
|---|
| neutrophil chemotaxis | GO:0030593 | | 7.658E-08 | 1.601E-05 |
|---|
VanDeVijver file
| Name | Accession Number | Link | P-val | Corrected P-val |
|---|
| angiogenesis | GO:0001525 | | 1.195E-08 | 2.202E-05 |
|---|
| blood vessel morphogenesis | GO:0048514 | | 9.619E-08 | 8.863E-05 |
|---|
| regulation of anatomical structure morphogenesis | GO:0022603 | | 1.273E-07 | 7.823E-05 |
|---|
| positive regulation of endothelial cell migration | GO:0010595 | | 1.557E-07 | 7.174E-05 |
|---|
| positive regulation of cell migration | GO:0030335 | | 1.577E-07 | 5.813E-05 |
|---|
| blood vessel development | GO:0001568 | | 2.56E-07 | 7.862E-05 |
|---|
| positive regulation of cell motion | GO:0051272 | | 2.599E-07 | 6.844E-05 |
|---|
| vasculature development | GO:0001944 | | 3.017E-07 | 6.949E-05 |
|---|
| regulation of cell migration | GO:0030334 | | 5.614E-07 | 1.15E-04 |
|---|
| positive regulation of MAP kinase activity | GO:0043406 | | 1.056E-06 | 1.946E-04 |
|---|
| regulation of locomotion | GO:0040012 | | 1.172E-06 | 1.964E-04 |
|---|
| Name | Accession Number | Link | P-val | Corrected P-val |
|---|
| anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | GO:0031145 | | 1.325E-08 | 3.047E-05 |
|---|
| positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle | GO:0051437 | | 1.512E-08 | 1.738E-05 |
|---|
| positive regulation of ubiquitin-protein ligase activity | GO:0051443 | | 2.216E-08 | 1.699E-05 |
|---|
| regulation of ubiquitin-protein ligase activity during mitotic cell cycle | GO:0051439 | | 2.216E-08 | 1.274E-05 |
|---|
| angiogenesis | GO:0001525 | | 2.94E-08 | 1.352E-05 |
|---|
| regulation of response to external stimulus | GO:0032101 | | 3.224E-08 | 1.236E-05 |
|---|
| positive regulation of ligase activity | GO:0051351 | | 3.583E-08 | 1.177E-05 |
|---|
| negative regulation of cellular protein metabolic process | GO:0032269 | | 4.227E-08 | 1.215E-05 |
|---|
| regulation of ubiquitin-protein ligase activity | GO:0051438 | | 4.504E-08 | 1.151E-05 |
|---|
| regulation of ligase activity | GO:0051340 | | 6.971E-08 | 1.603E-05 |
|---|
| neutrophil chemotaxis | GO:0030593 | | 7.658E-08 | 1.601E-05 |
|---|
