pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6725-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 7,000 3,475E-09 8,361E-06 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 7,000 3,913E-09 4,707E-06 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 7,000 5,525E-09 4,431E-06 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 7,000 5,525E-09 3,323E-06 ! positive regulation of ligase activity GO:0051351 124 77 7,000 9,493E-09 4,568E-06 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 7,000 1,166E-08 4,677E-06 ! regulation of ligase activity GO:0051340 142 84 7,000 1,905E-08 6,547E-06 ! neutrophil chemotaxis GO:0030593 27 17 4,000 2,564E-08 7,71E-06 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 7,000 4,27E-08 1,142E-05 GO:0010498|proteasomal protein catabolic process, ! positive regulation of endothelial cell migration GO:0010595 19 8 3,000 5,692E-08 1,369E-05 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 3,000 5,692E-08 1,245E-05 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 6,000 7,913E-08 1,586E-05 ! positive regulation of locomotion GO:0040017 39 21 4,000 8,284E-08 1,533E-05 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! negative regulation of ligase activity GO:0051352 112 68 6,000 8,781E-08 1,509E-05 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! cell proliferation in forebrain GO:0021846 15 9 3,000 1,02E-07 1,636E-05 ! induction of positive chemotaxis GO:0050930 15 9 3,000 1,02E-07 1,534E-05 ! regulation of chemotaxis GO:0050920 40 22 4,000 1,067E-07 1,511E-05 ! regulation of behavior GO:0050795 43 24 4,000 1,708E-07 2,283E-05 ! positive regulation of cell cycle GO:0045787 89 48 5,000 2,33E-07 2,951E-05 ! response to hypoxia GO:0001666 171 81 6,000 2,969E-07 3,572E-05 ! response to oxygen levels GO:0070482 176 83 6,000 3,514E-07 4,026E-05 ! regulation of positive chemotaxis GO:0050926 19 12 3,000 3,957E-07 4,328E-05 GO:0050927|positive regulation of positive chemotaxis, ! positive regulation of cell migration GO:0030335 126 57 5,000 6,619E-07 6,924E-05 ! positive regulation of MAP kinase activity GO:0043406 160 93 6,000 7,662E-07 7,681E-05 ! negative regulation of response to stimulus GO:0048585 100 60 5,000 9,01E-07 8,671E-05 ! leukocyte chemotaxis GO:0030595 50 33 4,000 9,168E-07 8,484E-05 GO:0060326|cell chemotaxis, ! epithelial to mesenchymal transition GO:0001837 28 15 3,000 1,077E-06 9,602E-05 ! positive regulation of cell motion GO:0051272 146 64 5,000 1,325E-06 1,139E-04 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 2,000 1,544E-06 1,281E-04 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 2,000 1,544E-06 1,238E-04 ! mesenchymal cell development GO:0014031 87 40 4,000 2,465E-06 1,913E-04 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of endothelial cell migration GO:0010594 44 19 3,000 3,008E-06 2,262E-04 ! eye development GO:0001654 143 74 5,000 3,132E-06 2,284E-04 ! positive regulation of response to external stimulus GO:0032103 77 43 4,000 3,559E-06 2,519E-04 ! regulation of epithelial cell proliferation GO:0050678 111 43 4,000 3,559E-06 2,447E-04 ! leukocyte migration GO:0050900 68 45 4,000 4,479E-06 2,993E-04 ! positive regulation of phosphorylation GO:0042327 129 79 5,000 4,596E-06 2,989E-04 ! collagen fibril organization GO:0030199 59 21 3,000 4,606E-06 2,916E-04 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 5,000 5,318E-06 3,281E-04 GO:0045937|positive regulation of phosphate metabolic process, ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 2,000 5,361E-06 3,225E-04 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 2,000 5,361E-06 3,146E-04 ! axonal fasciculation GO:0007413 18 7 2,000 5,361E-06 3,071E-04 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 3,000 5,606E-06 3,137E-04 ! negative regulation of transport GO:0051051 153 84 5,000 6,573E-06 3,594E-04 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 4,000 8,388E-06 4,485E-04 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 2,000 8,544E-06 4,469E-04 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 2,000 8,544E-06 4,374E-04 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 2,000 8,544E-06 4,283E-04 ! myelination GO:0042552 45 25 3,000 9,573E-06 4,7E-04 ! regulation of blood coagulation GO:0030193 40 25 3,000 9,573E-06 4,606E-04 ! negative regulation of actin filament depolymerization GO:0030835 55 26 3,000 1,127E-05 5,315E-04 ! regulation of endothelial cell proliferation GO:0001936 57 26 3,000 1,127E-05 5,212E-04 ! positive regulation of nuclear division GO:0051785 40 26 3,000 1,127E-05 5,114E-04 GO:0045840|positive regulation of mitosis, ! negative regulation of multicellular organismal process GO:0051241 166 93 5,000 1,184E-05 5,276E-04 ! RNA elongation GO:0006354 79 55 4,000 1,221E-05 5,34E-04 ! transcription initiation GO:0006352 153 94 5,000 1,259E-05 5,41E-04 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 2,000 1,276E-05 5,388E-04 GO:0010469|regulation of receptor activity, ! middle ear morphogenesis GO:0042474 14 9 2,000 1,276E-05 5,295E-04 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 3,000 1,317E-05 5,37E-04 ! regulation of actin filament depolymerization GO:0030834 58 28 3,000 1,53E-05 6,135E-04 ! negative regulation of protein modification process GO:0031400 60 28 3,000 1,53E-05 6,034E-04 ! regulation of coagulation GO:0050818 46 29 3,000 1,767E-05 6,858E-04 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 2,000 1,816E-05 6,937E-04 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 2,000 1,816E-05 6,828E-04 ! positive regulation of heart contraction GO:0045823 16 10 2,000 1,816E-05 6,723E-04 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 2,000 1,816E-05 6,621E-04 ! positive regulation of leukocyte migration GO:0002687 25 10 2,000 1,816E-05 6,522E-04 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 2,000 1,816E-05 6,427E-04 ! regulation of heart contraction GO:0008016 110 60 4,000 1,875E-05 6,539E-04 ! ensheathment of neurons GO:0007272 57 30 3,000 2,031E-05 6,979E-04 GO:0008366|axon ensheathment, ! detection of mechanical stimulus GO:0050982 22 11 2,000 2,487E-05 8,429E-04 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 2,000 2,487E-05 8,312E-04 ! chondrocyte differentiation GO:0002062 24 11 2,000 2,487E-05 8,198E-04 ! regulation of leukocyte migration GO:0002685 26 11 2,000 2,487E-05 8,088E-04 ! negative regulation of glucose import GO:0046325 17 11 2,000 2,487E-05 7,98E-04 GO:0010829|negative regulation of glucose transport, ! prepulse inhibition GO:0060134 18 11 2,000 2,487E-05 7,875E-04 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 4,000 3,216E-05 1,005E-03 ! regulation of RNA splicing GO:0043484 20 12 2,000 3,303E-05 1,019E-03 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 2,000 3,303E-05 1,006E-03 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 3,000 3,799E-05 1,142E-03 ! plasma membrane organization GO:0007009 24 13 2,000 4,277E-05 1,271E-03 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 2,000 4,277E-05 1,255E-03 ! regulation of actin cytoskeleton organization GO:0032956 149 74 4,000 5,204E-05 1,508E-03 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 3,000 5,288E-05 1,515E-03 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 2,000 5,422E-05 1,535E-03 ! regulation of mRNA processing GO:0050684 24 14 2,000 5,422E-05 1,517E-03 ! regulation of action potential in neuron GO:0019228 73 39 3,000 5,867E-05 1,623E-03 ! regulation of actin filament-based process GO:0032970 152 77 4,000 6,3E-05 1,722E-03 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 4,000 6,702E-05 1,812E-03 ! positive regulation of cell size GO:0045793 27 15 2,000 6,751E-05 1,805E-03 ! regulation of the force of heart contraction GO:0002026 26 15 2,000 6,751E-05 1,785E-03 ! negative regulation of protein complex disassembly GO:0043242 101 42 3,000 7,884E-05 2,062E-03 ! regulation of neuron differentiation GO:0045664 167 81 4,000 8,029E-05 2,077E-03 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 2,000 8,276E-05 2,118E-03 ! startle response GO:0001964 28 16 2,000 8,276E-05 2,096E-03 ! neuron recognition GO:0008038 35 16 2,000 8,276E-05 2,074E-03 ! positive regulation of neuron apoptosis GO:0043525 32 16 2,000 8,276E-05 2,053E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 1,001E-04 2,457E-03 ! negative regulation of blood coagulation GO:0030195 24 17 2,000 1,001E-04 2,433E-03 ! branching morphogenesis of a tube GO:0048754 97 45 3,000 1,036E-04 2,494E-03 ! induction of apoptosis by intracellular signals GO:0008629 93 45 3,000 1,036E-04 2,469E-03 ! patterning of blood vessels GO:0001569 39 18 2,000 1,196E-04 2,822E-03 ! regulation of cell morphogenesis GO:0022604 215 89 4,000 1,256E-04 2,934E-03 ! actin filament bundle formation GO:0051017 42 19 2,000 1,415E-04 3,274E-03 ! regulation of action potential GO:0001508 95 49 3,000 1,449E-04 3,321E-03 ! regulation of protein complex disassembly GO:0043244 113 49 3,000 1,449E-04 3,289E-03 ! regulation of membrane potential GO:0042391 164 93 4,000 1,546E-04 3,476E-03 ! neuromuscular process GO:0050905 99 50 3,000 1,569E-04 3,494E-03 ! negative regulation of immune system process GO:0002683 95 50 3,000 1,569E-04 3,462E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 1,658E-04 3,627E-03 ! regulation of glucose import GO:0046324 29 20 2,000 1,658E-04 3,594E-03 GO:0010827|regulation of glucose transport, ! negative regulation of coagulation GO:0050819 29 20 2,000 1,658E-04 3,562E-03 ! forebrain development GO:0030900 188 95 4,000 1,708E-04 3,638E-03 ! regulation of angiogenesis GO:0045765 114 52 3,000 1,828E-04 3,859E-03 ! regulation of muscle contraction GO:0006937 81 52 3,000 1,828E-04 3,825E-03 ! morphogenesis of a branching structure GO:0001763 111 52 3,000 1,828E-04 3,793E-03 ! cartilage development GO:0051216 90 52 3,000 1,828E-04 3,76E-03 ! phosphatidylinositol metabolic process GO:0046488 36 21 2,000 1,927E-04 3,929E-03 ! inactivation of MAPK activity GO:0000188 39 21 2,000 1,927E-04 3,896E-03 ! regulation of vasoconstriction GO:0019229 39 21 2,000 1,927E-04 3,863E-03 ! positive regulation of inflammatory response GO:0050729 35 21 2,000 1,927E-04 3,831E-03 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 3,000 1,969E-04 3,884E-03 ! negative regulation of cytoskeleton organization GO:0051494 124 54 3,000 2,118E-04 4,143E-03 ! calcium-independent cell-cell adhesion GO:0016338 30 22 2,000 2,222E-04 4,312E-03 ! regulation of actin filament length GO:0030832 105 56 3,000 2,439E-04 4,695E-03 ! positive regulation of organelle organization GO:0010638 100 56 3,000 2,439E-04 4,658E-03 ! positive regulation of cell adhesion GO:0045785 56 23 2,000 2,545E-04 4,822E-03 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 1,000 2,88E-04 5,414E-03 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! negative regulation of bone resorption GO:0045779 10 5 1,000 2,88E-04 5,372E-03 ! cell migration involved in gastrulation GO:0042074 7 5 1,000 2,88E-04 5,331E-03 ! apoptotic cell clearance GO:0043277 20 5 1,000 2,88E-04 5,29E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 2,88E-04 5,25E-03 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 1,000 2,88E-04 5,211E-03 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 2,88E-04 5,172E-03 ! microvillus organization GO:0032528 7 5 1,000 2,88E-04 5,133E-03 GO:0030033|microvillus assembly, ! mRNA transcription GO:0009299 9 5 1,000 2,88E-04 5,096E-03 ! morphogenesis of an epithelial sheet GO:0002011 11 5 1,000 2,88E-04 5,058E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 2,88E-04 5,022E-03 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 1,000 2,88E-04 4,986E-03 ! muscle cell proliferation GO:0033002 11 5 1,000 2,88E-04 4,95E-03 ! positive regulation of blood coagulation GO:0030194 11 5 1,000 2,88E-04 4,915E-03 ! positive regulation of macrophage activation GO:0043032 12 5 1,000 2,88E-04 4,88E-03 ! regulation of hair follicle development GO:0051797 10 5 1,000 2,88E-04 4,846E-03 GO:0042634|regulation of hair cycle, ! glial cell migration GO:0008347 11 5 1,000 2,88E-04 4,813E-03 ! negative regulation of fibrinolysis GO:0051918 11 5 1,000 2,88E-04 4,779E-03 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 1,000 2,88E-04 4,747E-03 GO:0022011|myelination in the peripheral nervous system, ! stem cell division GO:0017145 11 5 1,000 2,88E-04 4,714E-03 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 1,000 2,88E-04 4,682E-03 ! regulation of cellular catabolic process GO:0031329 52 24 2,000 2,897E-04 4,679E-03 ! negative regulation of phosphorylation GO:0042326 47 24 2,000 2,897E-04 4,648E-03 ! regulation of cellular component size GO:0032535 109 59 3,000 2,985E-04 4,756E-03 ! vasculogenesis GO:0001570 46 25 2,000 3,28E-04 5,191E-03 ! ear development GO:0043583 103 62 3,000 3,613E-04 5,681E-03 ! regulation of homeostatic process GO:0032844 134 62 3,000 3,613E-04 5,644E-03 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 3,693E-04 5,732E-03 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 2,000 3,693E-04 5,695E-03 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of mitosis GO:0007088 105 63 3,000 3,842E-04 5,887E-03 GO:0051783|regulation of nuclear division, ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 2,000 4,138E-04 6,301E-03 ! regulation of hormone biosynthetic process GO:0046885 10 6 1,000 4,305E-04 6,515E-03 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 1,000 4,305E-04 6,474E-03 ! vascular smooth muscle contraction GO:0014829 13 6 1,000 4,305E-04 6,434E-03 ! positive regulation of muscle hypertrophy GO:0014742 10 6 1,000 4,305E-04 6,394E-03 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! neural nucleus development GO:0048857 14 6 1,000 4,305E-04 6,355E-03 ! astrocyte development GO:0014002 15 6 1,000 4,305E-04 6,316E-03 ! Schwann cell development GO:0014044 15 6 1,000 4,305E-04 6,278E-03 ! receptor internalization GO:0031623 10 6 1,000 4,305E-04 6,24E-03 ! salivary gland morphogenesis GO:0007435 13 6 1,000 4,305E-04 6,202E-03 ! progesterone metabolic process GO:0042448 10 6 1,000 4,305E-04 6,166E-03 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 1,000 4,305E-04 6,129E-03 ! negative regulation of axon extension GO:0030517 21 6 1,000 4,305E-04 6,093E-03 ! positive regulation of coagulation GO:0050820 12 6 1,000 4,305E-04 6,057E-03 ! extracellular matrix organization GO:0030198 133 66 3,000 4,59E-04 6,421E-03 ! negative regulation of protein kinase activity GO:0006469 130 67 3,000 4,861E-04 6,76E-03 ! activation of MAPK activity GO:0000187 115 67 3,000 4,861E-04 6,722E-03 ! negative regulation of kinase activity GO:0033673 131 68 3,000 5,143E-04 7,071E-03 ! eye morphogenesis GO:0048592 60 30 2,000 5,675E-04 7,758E-03 ! negative regulation of cellular catabolic process GO:0031330 12 7 1,000 6,006E-04 8,164E-03 ! neuron adhesion GO:0007158 12 7 1,000 6,006E-04 8,118E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 6,006E-04 8,073E-03 ! mRNA stabilization GO:0048255 18 7 1,000 6,006E-04 8,028E-03 GO:0043489|RNA stabilization, ! fibril organization GO:0043206 16 7 1,000 6,006E-04 7,983E-03 ! positive regulation of heart rate GO:0010460 10 7 1,000 6,006E-04 7,939E-03 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 1,000 6,006E-04 7,896E-03 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 1,000 6,006E-04 7,853E-03 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 1,000 6,006E-04 7,811E-03 ! regulation of granule cell precursor proliferation GO:0021936 13 7 1,000 6,006E-04 7,769E-03 GO:0021940|positive regulation of granule cell precursor proliferation, ! phasic smooth muscle contraction GO:0014821 12 7 1,000 6,006E-04 7,727E-03 ! melanosome organization GO:0032438 9 7 1,000 6,006E-04 7,686E-03 ! wound healing, spreading of epidermal cells GO:0035313 14 7 1,000 6,006E-04 7,645E-03 ! fibrinolysis GO:0042730 10 7 1,000 6,006E-04 7,605E-03 ! negative regulation of focal adhesion formation GO:0051895 20 7 1,000 6,006E-04 7,565E-03 ! cranial nerve morphogenesis GO:0021602 11 7 1,000 6,006E-04 7,526E-03 ! regulation of lipid transport GO:0032368 14 7 1,000 6,006E-04 7,487E-03 ! diuresis GO:0030146 12 7 1,000 6,006E-04 7,448E-03 GO:0030147|natriuresis, ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 1,000 6,006E-04 7,41E-03 GO:0002688|regulation of leukocyte chemotaxis, ! dopamine biosynthetic process GO:0042416 18 7 1,000 6,006E-04 7,372E-03 ! glycolipid catabolic process GO:0019377 15 7 1,000 6,006E-04 7,335E-03 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of nucleotide metabolic process GO:0045980 11 7 1,000 6,006E-04 7,298E-03 ! positive regulation of smooth muscle contraction GO:0045987 10 7 1,000 6,006E-04 7,261E-03 ! phosphoinositide metabolic process GO:0030384 128 72 3,000 6,389E-04 7,686E-03 ! negative regulation of transferase activity GO:0051348 140 72 3,000 6,389E-04 7,648E-03 ! axon guidance GO:0007411 139 73 3,000 6,731E-04 8,018E-03 ! negative regulation of response to external stimulus GO:0032102 47 32 2,000 6,879E-04 8,153E-03 ! response to mechanical stimulus GO:0009612 57 32 2,000 6,879E-04 8,113E-03 ! regulation of axonogenesis GO:0050770 75 32 2,000 6,879E-04 8,073E-03 ! negative regulation of MAP kinase activity GO:0043407 69 32 2,000 6,879E-04 8,034E-03 ! peripheral nervous system development GO:0007422 64 32 2,000 6,879E-04 7,995E-03 ! hindbrain development GO:0030902 61 32 2,000 6,879E-04 7,957E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 7,979E-04 9,186E-03 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 1,000 7,979E-04 9,142E-03 ! T-helper 1 type immune response GO:0042088 12 8 1,000 7,979E-04 9,099E-03 ! ganglioside metabolic process GO:0001573 19 8 1,000 7,979E-04 9,056E-03 ! inositol phosphate-mediated signaling GO:0048016 11 8 1,000 7,979E-04 9,013E-03 ! pigment granule organization GO:0048753 16 8 1,000 7,979E-04 8,971E-03 ! astrocyte differentiation GO:0048708 18 8 1,000 7,979E-04 8,929E-03 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 1,000 7,979E-04 8,888E-03 ! regulation of muscle hypertrophy GO:0014743 12 8 1,000 7,979E-04 8,847E-03 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! regulation of vascular permeability GO:0043114 12 8 1,000 7,979E-04 8,806E-03 ! Schwann cell differentiation GO:0014037 19 8 1,000 7,979E-04 8,766E-03 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 7,979E-04 8,726E-03 ! regulation of focal adhesion formation GO:0051893 22 8 1,000 7,979E-04 8,687E-03 ! regulation of macrophage activation GO:0043030 15 8 1,000 7,979E-04 8,648E-03 ! positive regulation of epidermis development GO:0045684 13 8 1,000 7,979E-04 8,609E-03 ! neuromuscular process controlling posture GO:0050884 14 8 1,000 7,979E-04 8,57E-03 ! negative regulation of organic acid transport GO:0032891 13 8 1,000 7,979E-04 8,532E-03 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 1,000 7,979E-04 8,495E-03 ! negative regulation of organelle organization GO:0010639 161 78 3,000 8,639E-04 9,157E-03 ! negative regulation of secretion GO:0051048 63 35 2,000 8,969E-04 9,465E-03 ! regulation of synaptic plasticity GO:0048167 64 35 2,000 8,969E-04 9,424E-03 ! calcium-mediated signaling GO:0019722 62 35 2,000 8,969E-04 9,383E-03 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 3,000 9,062E-04 9,438E-03 ! activation of protein kinase activity GO:0032147 147 79 3,000 9,062E-04 9,398E-03 ! regulation of synaptic transmission GO:0050804 134 79 3,000 9,062E-04 9,357E-03 ! androgen receptor signaling pathway GO:0030521 74 36 2,000 9,746E-04 0,01002106 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 1,022E-03 0,01046606 ! regulation of glycolysis GO:0006110 21 9 1,000 1,022E-03 0,01042171 ! cerebral cortex cell migration GO:0021795 15 9 1,000 1,022E-03 0,01037774 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 1,022E-03 0,01033413 ! ruffle organization GO:0031529 15 9 1,000 1,022E-03 0,0102909 ! motor axon guidance GO:0008045 16 9 1,000 1,022E-03 0,01024802 ! establishment of melanosome localization GO:0032401 14 9 1,000 1,022E-03 0,01020549 ! renal water homeostasis GO:0003091 14 9 1,000 1,022E-03 0,01016332 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 1,000 1,022E-03 0,0101215 ! positive regulation of erythrocyte differentiation GO:0045648 29 9 1,000 1,022E-03 0,01008002 ! regulation of fibrinolysis GO:0051917 16 9 1,000 1,022E-03 0,01003887 ! regulation of telomere maintenance GO:0032204 14 9 1,000 1,022E-03 9,998E-03 ! regulation of muscle adaptation GO:0043502 14 9 1,000 1,022E-03 9,958E-03 ! cellular response to insulin stimulus GO:0032869 82 37 2,000 1,056E-03 0,01024898 ! regulation of transmission of nerve impulse GO:0051969 141 84 3,000 1,14E-03 0,01101172 ! regulation of neuron projection development GO:0010975 91 38 2,000 1,142E-03 0,01099482 ! ear morphogenesis GO:0042471 60 39 2,000 1,233E-03 0,01181673 ! tube morphogenesis GO:0035239 176 86 3,000 1,244E-03 0,01187523 ! regulation of phosphatase activity GO:0010921 28 10 1,000 1,273E-03 0,01210862 ! SMAD protein nuclear translocation GO:0007184 20 10 1,000 1,273E-03 0,01206094 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 1,273E-03 0,01201365 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 1,000 1,273E-03 0,01196672 ! lung alveolus development GO:0048286 26 10 1,000 1,273E-03 0,01192016 ! phagocytosis, engulfment GO:0006911 28 10 1,000 1,273E-03 0,01187395 ! lens development in camera-type eye GO:0002088 16 10 1,000 1,273E-03 0,01182811 ! positive regulation of muscle contraction GO:0045933 14 10 1,000 1,273E-03 0,01178261 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 1,000 1,273E-03 0,01173747 ! regulation of bone resorption GO:0045124 25 10 1,000 1,273E-03 0,01169267 ! negative regulation of axonogenesis GO:0050771 32 10 1,000 1,273E-03 0,01164821 ! melanosome localization GO:0032400 16 10 1,000 1,273E-03 0,01160409 ! salivary gland development GO:0007431 27 10 1,000 1,273E-03 0,0115603 ! apical protein localization GO:0045176 15 10 1,000 1,273E-03 0,01151684 ! midbrain development GO:0030901 13 10 1,000 1,273E-03 0,01147371 ! multicellular organismal water homeostasis GO:0050891 15 10 1,000 1,273E-03 0,0114309 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 1,273E-03 0,0113884 GO:0043470|regulation of carbohydrate catabolic process, ! establishment of pigment granule localization GO:0051905 18 10 1,000 1,273E-03 0,01134622 ! localization within membrane GO:0051668 20 10 1,000 1,273E-03 0,01130435 ! gland development GO:0048732 206 88 3,000 1,354E-03 0,01198089 ! regulation of neurological system process GO:0031644 148 88 3,000 1,354E-03 0,011937 ! regulation of cell adhesion GO:0030155 212 89 3,000 1,412E-03 0,01240122 ! gliogenesis GO:0042063 88 41 2,000 1,427E-03 0,0124813 ! dorsal/ventral pattern formation GO:0009953 68 41 2,000 1,427E-03 0,01243608 ! regulation of cell cycle process GO:0010564 149 90 3,000 1,472E-03 0,01278396 ! telencephalon cell migration GO:0022029 20 11 1,000 1,551E-03 0,0134207 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 1,551E-03 0,01337259 ! blood vessel remodeling GO:0001974 29 11 1,000 1,551E-03 0,01332483 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 1,000 1,551E-03 0,01327741 GO:0010812|negative regulation of cell-substrate adhesion, ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 1,551E-03 0,01323033 ! negative regulation of proteolysis GO:0045861 25 11 1,000 1,551E-03 0,01318358 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 1,000 1,551E-03 0,01313716 ! pigment granule localization GO:0051875 20 11 1,000 1,551E-03 0,01309106 ! vasoconstriction GO:0042310 18 11 1,000 1,551E-03 0,01304529 ! regulation of organic acid transport GO:0032890 18 11 1,000 1,551E-03 0,01299984 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 2,000 1,639E-03 0,01368857 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 2,000 1,639E-03 0,0136412 ! glucose transport GO:0015758 65 43 2,000 1,639E-03 0,01359416 ! hexose transport GO:0008645 67 44 2,000 1,751E-03 0,01448136 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 2,000 1,751E-03 0,01443176 ! negative regulation of cell projection organization GO:0031345 37 12 1,000 1,854E-03 0,0152261 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 1,854E-03 0,01517431 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 1,854E-03 0,01512287 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 1,000 1,854E-03 0,01507178 ! positive regulation of cell growth GO:0030307 22 12 1,000 1,854E-03 0,01502104 ! negative regulation of endothelial cell migration GO:0010596 25 12 1,000 1,854E-03 0,01497063 ! forebrain cell migration GO:0021885 21 12 1,000 1,854E-03 0,01492056 ! asymmetric protein localization GO:0008105 20 12 1,000 1,854E-03 0,01487083 ! regulation of interleukin-12 production GO:0032655 19 12 1,000 1,854E-03 0,01482142 ! cranial nerve development GO:0021545 20 12 1,000 1,854E-03 0,01477234 ! histone acetylation GO:0016573 26 12 1,000 1,854E-03 0,01472359 ! autonomic nervous system development GO:0048483 24 12 1,000 1,854E-03 0,01467516 ! gland morphogenesis GO:0022612 29 12 1,000 1,854E-03 0,01462704 ! regulation of hormone metabolic process GO:0032350 26 12 1,000 1,854E-03 0,01457924 ! peptidyl-lysine modification GO:0018205 21 12 1,000 1,854E-03 0,01453175 ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 1,854E-03 0,01448457 GO:0042130|negative regulation of T cell proliferation, ! detection of stimulus involved in sensory perception GO:0050906 66 45 2,000 1,869E-03 0,01455427 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 1,992E-03 0,01545825 ! negative regulation of cell migration GO:0030336 115 46 2,000 1,992E-03 0,01540855 ! pigmentation GO:0043473 100 46 2,000 1,992E-03 0,01535916 ! response to insulin stimulus GO:0032868 95 46 2,000 1,992E-03 0,01531009 ! positive regulation of defense response GO:0031349 76 47 2,000 2,119E-03 0,01623761 ! vascular process in circulatory system GO:0003018 80 47 2,000 2,119E-03 0,01618606 ! cell cycle arrest GO:0007050 213 100 3,000 2,166E-03 0,01649436 ! lipid localization GO:0010876 28 13 1,000 2,184E-03 0,0165731 GO:0019915|lipid storage, ! exocrine system development GO:0035272 32 13 1,000 2,184E-03 0,01652098 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 2,184E-03 0,01646919 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of monooxygenase activity GO:0032768 33 13 1,000 2,184E-03 0,01641773 ! gastrulation with mouth forming second GO:0001702 25 13 1,000 2,184E-03 0,01636658 ! regulation of epidermis development GO:0045682 19 13 1,000 2,184E-03 0,01631575 ! regulation of mRNA stability GO:0043488 31 13 1,000 2,184E-03 0,01626524 ! embryonic placenta development GO:0001892 23 13 1,000 2,184E-03 0,01621504 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 2,000 2,251E-03 0,01666793 ! regulation of inflammatory response GO:0050727 75 48 2,000 2,251E-03 0,0166168 ! induction of apoptosis by extracellular signals GO:0008624 89 49 2,000 2,389E-03 0,01757684 ! detection of abiotic stimulus GO:0009582 74 49 2,000 2,389E-03 0,01752325 ! regulation of cell projection organization GO:0031344 121 50 2,000 2,531E-03 0,01851188 ! positive regulation of cytokine production GO:0001819 86 50 2,000 2,531E-03 0,01845578 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 2,538E-03 0,01845178 ! hair follicle morphogenesis GO:0031069 26 14 1,000 2,538E-03 0,01839621 ! regulation of heart rate GO:0002027 24 14 1,000 2,538E-03 0,01834096 ! regulation of erythrocyte differentiation GO:0045646 44 14 1,000 2,538E-03 0,01828605 ! cAMP biosynthetic process GO:0006171 23 14 1,000 2,538E-03 0,01823146 ! catecholamine biosynthetic process GO:0042423 30 14 1,000 2,538E-03 0,0181772 ! regulation of RNA stability GO:0043487 32 14 1,000 2,538E-03 0,01812327 ! regulation of axon extension GO:0030516 37 14 1,000 2,538E-03 0,01806965 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 2,538E-03 0,01801634 ! positive regulation of growth GO:0045927 90 52 2,000 2,832E-03 0,02003901 ! negative regulation of bone remodeling GO:0046851 33 15 1,000 2,919E-03 0,02059288 ! response to hexose stimulus GO:0009746 22 15 1,000 2,919E-03 0,02053267 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pituitary gland development GO:0021983 29 15 1,000 2,919E-03 0,02047281 ! water homeostasis GO:0030104 27 15 1,000 2,919E-03 0,02041329 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 1,000 2,919E-03 0,02035413 ! dopamine metabolic process GO:0042417 35 15 1,000 2,919E-03 0,0202953 ! regulation of neuron apoptosis GO:0043523 100 53 2,000 2,99E-03 0,02073091 ! activation of phospholipase C activity GO:0007202 103 54 2,000 3,153E-03 0,02180116 GO:0010863|positive regulation of phospholipase C activity, ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 2,000 3,153E-03 0,02173869 ! cell recognition GO:0008037 85 54 2,000 3,153E-03 0,02167658 ! positive regulation of phospholipase activity GO:0010518 104 55 2,000 3,322E-03 0,02277188 ! negative regulation of cell motion GO:0051271 134 55 2,000 3,322E-03 0,02270719 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 3,324E-03 0,02265409 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 1,000 3,324E-03 0,0225901 ! activation of MAPKK activity GO:0000186 35 16 1,000 3,324E-03 0,02252647 ! regulation of dephosphorylation GO:0035303 43 16 1,000 3,324E-03 0,02246319 ! negative regulation of immune response GO:0050777 35 16 1,000 3,324E-03 0,02240027 ! embryonic digit morphogenesis GO:0042733 34 16 1,000 3,324E-03 0,0223377 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 3,324E-03 0,02227547 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 3,324E-03 0,0222136 ! sphingolipid catabolic process GO:0030149 27 16 1,000 3,324E-03 0,02215207 GO:0046466|membrane lipid catabolic process, ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 3,324E-03 0,02209087 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 2,000 3,676E-03 0,02436518 ! regulation of bone remodeling GO:0046850 137 57 2,000 3,676E-03 0,02429824 ! regulation of phospholipase activity GO:0010517 106 57 2,000 3,676E-03 0,02423167 ! negative regulation of hormone secretion GO:0046888 25 17 1,000 3,754E-03 0,02467497 ! endothelial cell migration GO:0043542 28 17 1,000 3,754E-03 0,02460773 ! glial cell development GO:0021782 27 17 1,000 3,754E-03 0,02454086 ! limbic system development GO:0021761 36 17 1,000 3,754E-03 0,02447436 ! regulation of muscle cell differentiation GO:0051147 33 17 1,000 3,754E-03 0,02440821 ! adult walking behavior GO:0007628 33 17 1,000 3,754E-03 0,02434242 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 1,000 3,754E-03 0,02427698 ! regulation of survival gene product expression GO:0045884 33 17 1,000 3,754E-03 0,0242119 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 3,754E-03 0,02414716 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 1,000 3,754E-03 0,02408277 ! negative regulation of homeostatic process GO:0032845 33 17 1,000 3,754E-03 0,02401872 ! regulation of tissue remodeling GO:0034103 140 58 2,000 3,861E-03 0,02464276 ! positive regulation of lipase activity GO:0060193 108 58 2,000 3,861E-03 0,02457757 ! skeletal system morphogenesis GO:0048705 105 59 2,000 4,052E-03 0,02572439 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 4,208E-03 0,02664194 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 1,000 4,208E-03 0,02657201 GO:0050886|endocrine process, ! epidermis morphogenesis GO:0048730 40 18 1,000 4,208E-03 0,02650245 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 1,000 4,208E-03 0,02643326 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 4,208E-03 0,02636442 ! nerve development GO:0021675 28 18 1,000 4,208E-03 0,02629594 ! camera-type eye development GO:0043010 116 60 2,000 4,249E-03 0,02648277 ! protein amino acid autophosphorylation GO:0046777 141 60 2,000 4,249E-03 0,02641434 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 4,451E-03 0,02760014 ! positive regulation of translation GO:0045727 30 19 1,000 4,686E-03 0,02898441 ! positive regulation of angiogenesis GO:0045766 44 19 1,000 4,686E-03 0,02891009 ! positive regulation of hormone secretion GO:0046887 32 19 1,000 4,686E-03 0,02883615 ! skin development GO:0043588 36 19 1,000 4,686E-03 0,02876259 ! lipid phosphorylation GO:0046834 35 19 1,000 4,686E-03 0,0286894 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 1,000 4,686E-03 0,02861659 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 4,686E-03 0,02854414 ! cerebral cortex development GO:0021987 36 19 1,000 4,686E-03 0,02847206 ! neuromuscular junction development GO:0007528 34 19 1,000 4,686E-03 0,02840034 ! peptide cross-linking GO:0018149 37 19 1,000 4,686E-03 0,02832898 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 1,000 4,686E-03 0,02825798 ! cellular pigmentation GO:0033059 36 19 1,000 4,686E-03 0,02818734 ! cell-cell junction organization GO:0045216 35 19 1,000 4,686E-03 0,02811705 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 1,000 4,686E-03 0,0280471 ! peptide hormone secretion GO:0030072 31 19 1,000 4,686E-03 0,02797751 ! detection of external stimulus GO:0009581 91 63 2,000 4,873E-03 0,02901837 ! steroid hormone receptor signaling pathway GO:0030518 129 63 2,000 4,873E-03 0,02894672 ! positive regulation of ossification GO:0045778 47 20 1,000 5,188E-03 0,03074724 ! protein amino acid acetylation GO:0006473 39 20 1,000 5,188E-03 0,03067169 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 5,188E-03 0,03059652 ! cAMP metabolic process GO:0046058 36 20 1,000 5,188E-03 0,03052171 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 5,188E-03 0,03044726 GO:0010675|regulation of cellular carbohydrate metabolic process, ! C21-steroid hormone metabolic process GO:0008207 33 20 1,000 5,188E-03 0,03037318 ! response to alkaloid GO:0043279 38 20 1,000 5,188E-03 0,03029946 ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 5,188E-03 0,0302261 ! response to carbohydrate stimulus GO:0009743 29 20 1,000 5,188E-03 0,03015309 ! body fluid secretion GO:0007589 31 20 1,000 5,188E-03 0,03008043 ! peptide secretion GO:0002790 35 20 1,000 5,188E-03 0,03000812 ! diencephalon development GO:0021536 34 20 1,000 5,188E-03 0,02993616 ! negative regulation of angiogenesis GO:0016525 45 20 1,000 5,188E-03 0,02986454 ! camera-type eye morphogenesis GO:0048593 42 20 1,000 5,188E-03 0,02979327 ! negative regulation of T cell activation GO:0050868 40 20 1,000 5,188E-03 0,02972233 ! negative regulation of translation GO:0017148 29 20 1,000 5,188E-03 0,02965173 ! embryonic limb morphogenesis GO:0030326 125 65 2,000 5,318E-03 0,03031781 GO:0035113|embryonic appendage morphogenesis, ! actin filament organization GO:0007015 148 66 2,000 5,549E-03 0,03156211 ! hormone secretion GO:0046879 38 21 1,000 5,714E-03 0,03242599 ! smooth muscle contraction GO:0006939 46 21 1,000 5,714E-03 0,03234969 ! cell structure disassembly during apoptosis GO:0006921 30 21 1,000 5,714E-03 0,03227375 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 1,000 5,714E-03 0,03219817 ! regulation of cellular response to stress GO:0080135 128 67 2,000 5,786E-03 0,03252749 ! lung development GO:0030324 144 67 2,000 5,786E-03 0,03245167 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 2,000 6,03E-03 0,03373766 ! regulation of lipase activity GO:0060191 130 68 2,000 6,03E-03 0,03365939 ! positive regulation of cytoskeleton organization GO:0051495 48 22 1,000 6,264E-03 0,03488429 ! renal system process GO:0003014 41 22 1,000 6,264E-03 0,03480373 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 6,264E-03 0,03472354 ! positive regulation of bone remodeling GO:0046852 51 22 1,000 6,264E-03 0,03464371 GO:0034105|positive regulation of tissue remodeling, ! glutamate signaling pathway GO:0007215 41 22 1,000 6,264E-03 0,03456426 ! lysosome organization GO:0007040 41 22 1,000 6,264E-03 0,03448516 ! apoptotic nuclear changes GO:0030262 32 22 1,000 6,264E-03 0,03440643 ! appendage morphogenesis GO:0035107 135 70 2,000 6,534E-03 0,0358126 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 2,000 6,534E-03 0,03573121 ! appendage development GO:0048736 136 71 2,000 6,796E-03 0,03707714 GO:0060173|limb development, ! regulation of MAPKKK cascade GO:0043408 142 71 2,000 6,796E-03 0,03699325 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 6,836E-03 0,03712625 GO:0010810|regulation of cell-substrate adhesion, ! activation of pro-apoptotic gene products GO:0008633 47 23 1,000 6,836E-03 0,03704263 ! barbed-end actin filament capping GO:0051016 50 23 1,000 6,836E-03 0,03695939 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 1,000 6,836E-03 0,03687652 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 1,000 6,836E-03 0,03679402 ! glycosphingolipid metabolic process GO:0006687 41 23 1,000 6,836E-03 0,0367119 ! hormone transport GO:0009914 40 23 1,000 6,836E-03 0,03663013 ! negative regulation of cytokine production GO:0001818 40 23 1,000 6,836E-03 0,03654873 ! negative regulation of catabolic process GO:0009895 50 23 1,000 6,836E-03 0,03646769 ! regulation of caspase activity GO:0043281 122 72 2,000 7,064E-03 0,03759977 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 2,000 7,064E-03 0,03751677 ! carbohydrate transport GO:0008643 110 72 2,000 7,064E-03 0,03743413 ! respiratory system development GO:0060541 153 72 2,000 7,064E-03 0,03735186 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 7,431E-03 0,03920774 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 1,000 7,431E-03 0,03912194 ! vacuole organization GO:0007033 43 24 1,000 7,431E-03 0,03903653 ! membrane depolarization GO:0051899 39 24 1,000 7,431E-03 0,03895148 ! pallium development GO:0021543 49 24 1,000 7,431E-03 0,0388668 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 7,431E-03 0,03878249 ! regulation of endopeptidase activity GO:0052548 125 74 2,000 7,618E-03 0,03967089 ! phosphoinositide-mediated signaling GO:0048015 131 75 2,000 7,904E-03 0,04107319 ! regulation of smooth muscle contraction GO:0006940 43 25 1,000 8,049E-03 0,04173445 ! receptor metabolic process GO:0043112 46 25 1,000 8,049E-03 0,0416447 ! neural crest cell development GO:0014032 54 25 1,000 8,049E-03 0,04155534 GO:0014033|neural crest cell differentiation, ! negative regulation of cell development GO:0010721 73 25 1,000 8,049E-03 0,04146635 GO:0050768|negative regulation of neurogenesis, ! somitogenesis GO:0001756 43 25 1,000 8,049E-03 0,04137775 ! neuromuscular process controlling balance GO:0050885 60 25 1,000 8,049E-03 0,04128952 ! regulation of catabolic process GO:0009894 161 76 2,000 8,197E-03 0,04195942 ! negative regulation of actin filament polymerization GO:0030837 53 26 1,000 8,688E-03 0,04438319 ! molting cycle process GO:0022404 50 26 1,000 8,688E-03 0,04428916 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 8,688E-03 0,04419552 ! cellular response to oxidative stress GO:0034599 39 26 1,000 8,688E-03 0,04410228 ! positive regulation of MAPKKK cascade GO:0043410 47 26 1,000 8,688E-03 0,04400944 ! positive regulation of JUN kinase activity GO:0043507 51 26 1,000 8,688E-03 0,04391698 ! blood coagulation GO:0007596 146 78 2,000 8,801E-03 0,04439122 GO:0050817|coagulation, ! regulation of peptidase activity GO:0052547 134 79 2,000 9,112E-03 0,04586692 ! protein amino acid acylation GO:0043543 55 27 1,000 9,35E-03 0,04696701 ! male gonad development GO:0008584 44 27 1,000 9,35E-03 0,04686916 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 1,000 9,35E-03 0,04677172 ! glycolipid metabolic process GO:0006664 47 27 1,000 9,35E-03 0,04667469 ! regulation of chromosome organization GO:0033044 42 27 1,000 9,35E-03 0,04657805 ! negative regulation of protein polymerization GO:0032272 55 27 1,000 9,35E-03 0,04648181 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 9,35E-03 0,04638598 ! dendrite development GO:0016358 59 28 1,000 0,01003422 0,04967556 ! regulation of systemic arterial blood pressure GO:0003073 54 28 1,000 0,01003422 0,04957356 ! regulation of JUN kinase activity GO:0043506 58 28 1,000 0,01003422 0,04947197 ! cellular response to hormone stimulus GO:0032870 167 82 2,000 0,01008572 0,04962419 ! negative regulation of protein complex assembly GO:0031333 59 29 1,000 0,0107395 0,05273316 ! regulation of pH GO:0006885 43 29 1,000 0,0107395 0,05262576 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 0,0107395 0,0525188 ! catechol metabolic process GO:0009712 54 29 1,000 0,0107395 0,05241227 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! respiratory gaseous exchange GO:0007585 57 29 1,000 0,0107395 0,05230617 ! hemostasis GO:0007599 158 84 2,000 0,01076689 0,05233361 ! phenol metabolic process GO:0018958 55 30 1,000 0,01146607 0,05561971 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 1,000 0,01146607 0,0555078 ! positive regulation of multicellular organism growth GO:0040018 51 30 1,000 0,01146607 0,05539633 ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 0,01146607 0,05528532 ! response to heat GO:0009408 50 30 1,000 0,01146607 0,05517475 ! regulation of protein transport GO:0051223 154 87 2,000 0,01183752 0,05684847 GO:0070201|regulation of establishment of protein localization, ! positive regulation of protein modification process GO:0031401 136 88 2,000 0,01220751 0,05850853 ! collagen metabolic process GO:0032963 45 31 1,000 0,01221368 0,05842168 ! peptide transport GO:0015833 55 31 1,000 0,01221368 0,05830576 ! iron ion homeostasis GO:0055072 54 31 1,000 0,01221368 0,0581903 ! metanephros development GO:0001656 74 32 1,000 0,01298206 0,06172894 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 0,01298206 0,06160719 ! BMP signaling pathway GO:0030509 64 32 1,000 0,01298206 0,06148591 ! positive regulation of catabolic process GO:0009896 64 32 1,000 0,01298206 0,06136512 ! regulation of defense response GO:0031347 149 92 2,000 0,01375352 0,06488424 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 0,01377099 0,06483955 ! ceramide metabolic process GO:0006672 64 33 1,000 0,01377099 0,06471291 ! adult locomotory behavior GO:0008344 59 33 1,000 0,01377099 0,06458676 ! establishment of vesicle localization GO:0051650 61 33 1,000 0,01377099 0,06446111 ! glial cell differentiation GO:0010001 63 34 1,000 0,01458022 0,06811653 ! regulation of striated muscle tissue development GO:0016202 69 34 1,000 0,01458022 0,06798453 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 1,000 0,01458022 0,06785303 ! biogenic amine biosynthetic process GO:0042401 62 34 1,000 0,01458022 0,06772204 ! placenta development GO:0001890 53 34 1,000 0,01458022 0,06759155 ! detection of stimulus GO:0051606 151 96 2,000 0,01540591 0,07128194 ! regulation of muscle development GO:0048634 70 35 1,000 0,01540951 0,07116178 ! negative regulation of cell adhesion GO:0007162 81 35 1,000 0,01540951 0,07102545 ! embryonic skeletal system morphogenesis GO:0048704 59 35 1,000 0,01540951 0,07088965 ! telencephalon development GO:0021537 68 35 1,000 0,01540951 0,07075436 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 0,01540951 0,07061959 ! vesicle localization GO:0051648 64 35 1,000 0,01540951 0,07048533 ! regulation of protein localization GO:0032880 176 97 2,000 0,01583572 0,07229744 ! cell junction organization GO:0034330 86 36 1,000 0,01625862 0,07408759 ! sphingoid metabolic process GO:0046519 70 36 1,000 0,01625862 0,07394754 ! positive regulation of cell development GO:0010720 80 36 1,000 0,01625862 0,07380802 ! regulation of proteolysis GO:0030162 72 36 1,000 0,01625862 0,07366902 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 1,000 0,01625862 0,07353054 ! hormone biosynthetic process GO:0042446 57 36 1,000 0,01625862 0,07339259 ! negative regulation of cell activation GO:0050866 65 36 1,000 0,01625862 0,07325515 ! skeletal muscle tissue development GO:0007519 186 99 2,000 0,0167155 0,07517286 GO:0060538|skeletal muscle organ development, ! tissue remodeling GO:0048771 76 37 1,000 0,01712732 0,07688122 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 0,01712732 0,07673805 ! cyclic nucleotide metabolic process GO:0009187 63 37 1,000 0,01712732 0,07659542 ! regulation of protein stability GO:0031647 73 37 1,000 0,01712732 0,07645331 ! nucleus organization GO:0006997 67 38 1,000 0,01801537 0,08026848 ! mammary gland development GO:0030879 86 39 1,000 0,01892254 0,08415458 ! development of primary male sexual characteristics GO:0046546 66 39 1,000 0,01892254 0,08399931 ! segmentation GO:0035282 67 39 1,000 0,01892254 0,08384462 ! response to xenobiotic stimulus GO:0009410 57 39 1,000 0,01892254 0,08369049 ! regulation of hormone secretion GO:0046883 62 40 1,000 0,0198486 0,08762518 ! multicellular organismal metabolic process GO:0044236 57 40 1,000 0,0198486 0,08746469 ! cytokinesis GO:0000910 72 40 1,000 0,0198486 0,08730479 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 1,000 0,02079331 0,09129328 ! regulation of T cell proliferation GO:0042129 71 41 1,000 0,02079331 0,09112699 ! regulation of T cell differentiation GO:0045580 70 41 1,000 0,02079331 0,0909613 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,02175647 0,09500193 GO:0090047|positive regulation of transcription regulator activity, ! regulation of tube size GO:0035150 71 42 1,000 0,02175647 0,09482982 GO:0050880|regulation of blood vessel size, ! regulation of intracellular protein transport GO:0033157 80 42 1,000 0,02175647 0,09465834 ! neuron migration GO:0001764 79 42 1,000 0,02175647 0,09448748 ! regulation of protein secretion GO:0050708 71 42 1,000 0,02175647 0,09431723 ! regulation of myeloid cell differentiation GO:0045637 98 42 1,000 0,02175647 0,09414759 ! epithelial cell differentiation GO:0030855 79 43 1,000 0,02273783 0,09821763 ! receptor-mediated endocytosis GO:0006898 88 43 1,000 0,02273783 0,09804161 ! phagocytosis GO:0006909 90 43 1,000 0,02273783 0,09786623 ! male sex differentiation GO:0046661 76 44 1,000 0,02373718 0,1019851 ! regulation of actin filament polymerization GO:0030833 87 45 1,000 0,0247543 0,10616548 ! cell growth GO:0016049 84 45 1,000 0,0247543 0,10597658 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 1,000 0,02578896 0,11021001 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 0,02578896 0,1100146 ! positive regulation of protein transport GO:0051222 72 46 1,000 0,02578896 0,10981989 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,02677155 0,11380272 ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02677155 0,11360201 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,02677155 0,11340201 ! neuron fate determination GO:0048664 7 5 0,000 0,02677155 0,11320271 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02677155 0,11300411 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,02677155 0,1128062 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,02677155 0,11260899 ! polyol transport GO:0015791 12 5 0,000 0,02677155 0,11241246 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,02677155 0,11221662 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02677155 0,11202146 ! response to superoxide GO:0000303 10 5 0,000 0,02677155 0,11182698 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,02677155 0,11163317 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,02677155 0,11144003 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02677155 0,11124756 ! female meiosis GO:0007143 7 5 0,000 0,02677155 0,11105576 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02677155 0,11086461 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02677155 0,11067412 ! cobalt ion transport GO:0006824 11 5 0,000 0,02677155 0,11048429 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,02677155 0,1102951 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,02677155 0,11010656 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02677155 0,10991867 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02677155 0,10973141 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,02677155 0,1095448 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,02677155 0,10935881 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02677155 0,10917346 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,02677155 0,10898873 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,02677155 0,10880463 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02677155 0,10862115 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02677155 0,10843828 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02677155 0,10825603 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,02677155 0,1080744 ! negative chemotaxis GO:0050919 14 5 0,000 0,02677155 0,10789337 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02677155 0,10771294 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02677155 0,10753312 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,02677155 0,1073539 ! behavioral response to pain GO:0048266 9 5 0,000 0,02677155 0,10717527 ! clathrin coat assembly GO:0048268 14 5 0,000 0,02677155 0,10699724 ! Notch receptor processing GO:0007220 8 5 0,000 0,02677155 0,1068198 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02677155 0,10664295 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02677155 0,10646668 ! micturition GO:0060073 9 5 0,000 0,02677155 0,10629099 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02677155 0,10611588 ! copulation GO:0007620 9 5 0,000 0,02677155 0,10594135 ! glial cell fate commitment GO:0021781 13 5 0,000 0,02677155 0,10576739 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,02677155 0,105594 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02677155 0,10542118 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02677155 0,10524892 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02677155 0,10507723 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02677155 0,10490609 ! grooming behavior GO:0007625 6 5 0,000 0,02677155 0,10473551 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02677155 0,10456549 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,02677155 0,10439601 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02677155 0,10422709 ! response to protozoan GO:0001562 10 5 0,000 0,02677155 0,10405871 ! lymph vessel development GO:0001945 10 5 0,000 0,02677155 0,10389087 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,02677155 0,10372357 ! endochondral ossification GO:0001958 16 5 0,000 0,02677155 0,10355682 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02677155 0,10339059 ! parathyroid gland development GO:0060017 13 5 0,000 0,02677155 0,1032249 ! anagen GO:0042640 6 5 0,000 0,02677155 0,10305974 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02677155 0,10289511 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02677155 0,102731 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,02677155 0,10256742 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,02677155 0,10240436 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,02677155 0,10224181 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,02677155 0,10207978 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,02677155 0,10191826 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,02677155 0,10175725 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,02677155 0,10159675 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02677155 0,10143676 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02677155 0,10127726 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,02677155 0,10111827 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,02677155 0,10095978 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02677155 0,10080178 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,02677155 0,10064428 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02677155 0,10048727 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02677155 0,10033075 ! histidine catabolic process GO:0006548 6 5 0,000 0,02677155 0,10017471 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02677155 0,10001916 ! valine metabolic process GO:0006573 10 5 0,000 0,02677155 0,09986409 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,02677155 0,0997095 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02677155 0,09955539 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,02677155 0,09940176 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,02677155 0,0992486 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02677155 0,09909591 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,02677155 0,09894369 ! polyol catabolic process GO:0046174 7 5 0,000 0,02677155 0,09879193 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02677155 0,09864064 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02677155 0,09848982 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02677155 0,09833945 ! muscle cell migration GO:0014812 8 5 0,000 0,02677155 0,09818954 ! mitochondrial fission GO:0000266 8 5 0,000 0,02677155 0,09804009 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,02677155 0,09789109 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,02677155 0,09774255 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,02677155 0,09759445 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,02677155 0,09744681 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02677155 0,09729961 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02677155 0,09715285 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02677155 0,09700654 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02677155 0,09686066 ! response to food GO:0032094 6 5 0,000 0,02677155 0,09671523 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02677155 0,09657022 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,02677155 0,09642566 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02677155 0,09628152 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,02677155 0,09613782 ! forebrain neuron development GO:0021884 13 5 0,000 0,02677155 0,09599455 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02677155 0,0958517 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02677155 0,09570927 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02677155 0,09556727 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02677155 0,09542569 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,02677155 0,09528453 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02677155 0,09514378 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,02677155 0,09500345 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,02677155 0,09486353 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02677155 0,09472403 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,02677155 0,09458493 ! basic amino acid transport GO:0015802 11 5 0,000 0,02677155 0,09444625 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02677155 0,09430796 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,02677155 0,09417009 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02677155 0,09403261 ! depyrimidination GO:0045008 10 5 0,000 0,02677155 0,09389554 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02677155 0,09375886 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02677155 0,09362259 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02677155 0,09348671 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,02677155 0,09335122 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,02677155 0,09321612 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,02677155 0,09308142 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02677155 0,0929471 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02677155 0,09281317 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02677155 0,09267963 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,02677155 0,09254647 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,02677155 0,09241369 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02677155 0,09228129 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02677155 0,09214927 ! response to arsenic GO:0046685 10 5 0,000 0,02677155 0,09201763 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,02677155 0,09188636 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02677155 0,09175547 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,02677155 0,09162495 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,02677155 0,0914948 ! response to cadmium ion GO:0046686 7 5 0,000 0,02677155 0,09136502 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,02677155 0,09123561 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,02677155 0,09110656 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02677155 0,09097788 ! decidualization GO:0046697 11 5 0,000 0,02677155 0,09084956 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,02677155 0,09072161 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,02677155 0,09059401 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02677155 0,09046677 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02677155 0,09033989 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,02677155 0,09021336 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02677155 0,09008719 ! neural tube patterning GO:0021532 7 5 0,000 0,02677155 0,08996137 ! embryonic cleavage GO:0040016 6 5 0,000 0,02677155 0,0898359 ! peroxisome fission GO:0016559 5 5 0,000 0,02677155 0,08971078 ! histone demethylation GO:0016577 10 5 0,000 0,02677155 0,08958601 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,02677155 0,08946158 ! mitotic recombination GO:0006312 9 5 0,000 0,02677155 0,0893375 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02677155 0,08921377 ! metaphase plate congression GO:0051310 7 5 0,000 0,02677155 0,08909037 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02677155 0,08896732 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02677155 0,08884461 ! enteric nervous system development GO:0048484 8 5 0,000 0,02677155 0,08872223 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,02677155 0,08860019 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,02677155 0,08847849 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,02677155 0,08835712 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02677155 0,08823608 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,02677155 0,08811538 ! plasminogen activation GO:0031639 5 5 0,000 0,02677155 0,087995 ! B cell homeostasis GO:0001782 13 5 0,000 0,02677155 0,08787495 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,02677155 0,08775523 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02677155 0,08763584 ! metaphase GO:0051323 8 5 0,000 0,02677155 0,08751677 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02677155 0,08739802 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02677155 0,08727959 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02677155 0,08716149 GO:0015991|ATP hydrolysis coupled proton transport, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,02677155 0,0870437 ! response to redox state GO:0051775 5 5 0,000 0,02677155 0,08692623 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,02677155 0,08680908 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,02677155 0,08669225 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02677155 0,08657573 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,02677155 0,08645952 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02677155 0,08634362 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,02677155 0,08622803 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02677155 0,08611275 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,02677155 0,08599778 ! striatum development GO:0021756 9 5 0,000 0,02677155 0,08588312 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,02677155 0,08576876 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,02677155 0,08565471 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02677155 0,08554096 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02677155 0,08542751 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,02677155 0,08531436 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02677155 0,08520151 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02677155 0,08508896 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02677155 0,0849767 ! neuroprotection GO:0043526 6 5 0,000 0,02677155 0,08486474 ! neural plate development GO:0001840 8 5 0,000 0,02677155 0,08475308 ! regulation of sensory perception GO:0051931 7 5 0,000 0,02677155 0,08464171 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02677155 0,08453063 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02677155 0,08441984 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,02677155 0,08430935 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,02677155 0,08419914 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02677155 0,08408922 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02677155 0,08397958 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02677155 0,08387023 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02677155 0,08376117 ! spindle assembly GO:0051225 6 5 0,000 0,02677155 0,08365239 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,02677155 0,08354389 GO:0016226|iron-sulfur cluster assembly, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02677155 0,08343567 ! drug metabolic process GO:0017144 6 5 0,000 0,02677155 0,08332774 ! organ regeneration GO:0031100 7 5 0,000 0,02677155 0,08322008 ! carnitine metabolic process GO:0009437 7 5 0,000 0,02677155 0,0831127 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,02677155 0,08300559 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02677155 0,08289876 ! response to calcium ion GO:0051592 81 47 1,000 0,02684095 0,08300685 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,02684095 0,0829003 ! regulation of JNK cascade GO:0046328 94 47 1,000 0,02684095 0,08279401 ! protein homooligomerization GO:0051260 76 47 1,000 0,02684095 0,082688 ! cellular component disassembly GO:0022411 86 48 1,000 0,02791006 0,08587161 ! activation of caspase activity GO:0006919 84 48 1,000 0,02791006 0,08576194 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 0,02791006 0,08565255 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 0,02791006 0,08554344 ! response to temperature stimulus GO:0009266 76 49 1,000 0,02899607 0,08875895 ! endocrine system development GO:0035270 104 49 1,000 0,02899607 0,08864617 ! regulation of ossification GO:0030278 117 50 1,000 0,03009876 0,09190054 ! histone modification GO:0016570 91 50 1,000 0,03009876 0,09178406 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 0,03009876 0,09166788 ! positive regulation of binding GO:0051099 78 51 1,000 0,03121794 0,09495621 ! embryonic skeletal system development GO:0048706 85 51 1,000 0,03121794 0,09483632 ! excretion GO:0007588 83 51 1,000 0,03121794 0,09471673 ! vesicle organization GO:0016050 107 51 1,000 0,03121794 0,09459743 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 0,03121794 0,09447844 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 1,000 0,03121794 0,09435975 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03203975 0,09672226 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03203975 0,09660106 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,03203975 0,09648016 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03203975 0,09635956 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03203975 0,09623926 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,03203975 0,09611926 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,03203975 0,09599956 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03203975 0,09588016 ! sleep GO:0030431 13 6 0,000 0,03203975 0,09576105 ! response to oxygen radical GO:0000305 11 6 0,000 0,03203975 0,09564224 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,03203975 0,09552372 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,03203975 0,0954055 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,03203975 0,09528757 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,03203975 0,09516993 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03203975 0,09505258 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,03203975 0,09493552 ! forebrain regionalization GO:0021871 8 6 0,000 0,03203975 0,09481875 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03203975 0,09470227 ! male meiosis GO:0007140 7 6 0,000 0,03203975 0,09458607 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03203975 0,09447015 ! response to zinc ion GO:0010043 9 6 0,000 0,03203975 0,09435452 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03203975 0,09423917 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,03203975 0,09412411 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,03203975 0,09400932 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03203975 0,09389482 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03203975 0,09378059 ! malate metabolic process GO:0006108 11 6 0,000 0,03203975 0,09366664 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,03203975 0,09355297 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,03203975 0,09343957 ! protein refolding GO:0042026 15 6 0,000 0,03203975 0,09332645 ! opsonization GO:0008228 8 6 0,000 0,03203975 0,0932136 ! mating behavior GO:0007617 7 6 0,000 0,03203975 0,09310102 ! neuron remodeling GO:0016322 15 6 0,000 0,03203975 0,09298872 ! erythrocyte maturation GO:0043249 7 6 0,000 0,03203975 0,09287668 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,03203975 0,09276492 ! equilibrioception GO:0050957 14 6 0,000 0,03203975 0,09265342 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,03203975 0,09254219 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,03203975 0,09243123 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03203975 0,09232053 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,03203975 0,0922101 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03203975 0,09209993 ! response to interferon-gamma GO:0034341 15 6 0,000 0,03203975 0,09199003 ! toxin metabolic process GO:0009404 11 6 0,000 0,03203975 0,09188039 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03203975 0,09177101 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03203975 0,09166188 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,03203975 0,09155302 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,03203975 0,09144442 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,03203975 0,09133607 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,03203975 0,09122798 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03203975 0,09112015 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,03203975 0,09101257 ! thymic T cell selection GO:0045061 12 6 0,000 0,03203975 0,09090524 ! protein lipoylation GO:0009249 10 6 0,000 0,03203975 0,09079817 ! cysteine metabolic process GO:0006534 10 6 0,000 0,03203975 0,09069135 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03203975 0,09058478 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,03203975 0,09047846 ! glutamate catabolic process GO:0006538 10 6 0,000 0,03203975 0,09037239 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,03203975 0,09026656 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03203975 0,09016099 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,03203975 0,09005566 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,03203975 0,08995058 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03203975 0,08984574 ! hyperosmotic response GO:0006972 9 6 0,000 0,03203975 0,08974115 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,03203975 0,0896368 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,03203975 0,08953269 ! urea metabolic process GO:0019627 7 6 0,000 0,03203975 0,08942882 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03203975 0,0893252 ! neutrophil activation GO:0042119 8 6 0,000 0,03203975 0,08922181 ! regulation of appetite GO:0032098 9 6 0,000 0,03203975 0,08911866 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03203975 0,08901576 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03203975 0,08891309 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03203975 0,08881065 ! neuron apoptosis GO:0051402 9 6 0,000 0,03203975 0,08870845 ! nucleoside salvage GO:0043174 9 6 0,000 0,03203975 0,08860649 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,03203975 0,08850476 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,03203975 0,08840326 ! T cell mediated immunity GO:0002456 16 6 0,000 0,03203975 0,088302 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03203975 0,08820097 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,03203975 0,08810017 ! carnitine transport GO:0015879 10 6 0,000 0,03203975 0,08799959 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,03203975 0,08789925 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03203975 0,08779914 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,03203975 0,08769925 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,03203975 0,0875996 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,03203975 0,08750016 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03203975 0,08740096 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,03203975 0,08730198 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,03203975 0,08720322 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,03203975 0,08710468 ! establishment of spindle localization GO:0051293 12 6 0,000 0,03203975 0,08700637 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,03203975 0,08690828 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,03203975 0,08681041 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,03203975 0,08671276 ! response to UV-C GO:0010225 11 6 0,000 0,03203975 0,08661533 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,03203975 0,08651812 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03203975 0,08642113 ! interaction with symbiont GO:0051702 13 6 0,000 0,03203975 0,08632435 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03203975 0,08622779 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03203975 0,08613145 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,03203975 0,08603532 ! response to copper ion GO:0046688 10 6 0,000 0,03203975 0,0859394 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,03203975 0,0858437 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,03203975 0,08574821 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03203975 0,08565294 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03203975 0,08555787 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03203975 0,08546302 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,03203975 0,08536838 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03203975 0,08527394 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,03203975 0,08517972 ! hair follicle maturation GO:0048820 7 6 0,000 0,03203975 0,0850857 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03203975 0,08499189 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,03203975 0,08489829 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03203975 0,08480489 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,03203975 0,0847117 ! subpallium development GO:0021544 10 6 0,000 0,03203975 0,08461871 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,03203975 0,08452593 ! histone ubiquitination GO:0016574 8 6 0,000 0,03203975 0,08443335 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,03203975 0,08434097 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03203975 0,08424879 ! G2 phase GO:0051319 16 6 0,000 0,03203975 0,08415682 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,03203975 0,08406504 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03203975 0,08397347 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,03203975 0,08388209 ! membrane to membrane docking GO:0022614 14 6 0,000 0,03203975 0,08379092 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03203975 0,08369994 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,03203975 0,08360916 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03203975 0,08351858 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,03203975 0,08342819 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,03203975 0,08333799 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03203975 0,083248 GO:0043011|myeloid dendritic cell differentiation, ! protein deubiquitination GO:0016579 14 6 0,000 0,03203975 0,08315819 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,03203975 0,08306858 ! protein destabilization GO:0031648 9 6 0,000 0,03203975 0,08297917 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03203975 0,08288994 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,03203975 0,08280091 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,03203975 0,08271207 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,03203975 0,08262341 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,03203975 0,08253495 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,03203975 0,08244668 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03203975 0,0823586 ! determination of adult lifespan GO:0008340 15 6 0,000 0,03203975 0,0822707 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,03203975 0,08218299 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,03203975 0,08209547 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03203975 0,08200813 ! catecholamine transport GO:0051937 9 6 0,000 0,03203975 0,08192098 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,03203975 0,08183402 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03203975 0,08174724 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,03203975 0,08166064 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,03203975 0,08157423 ! maternal placenta development GO:0001893 12 6 0,000 0,03203975 0,081488 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,03203975 0,08140195 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03203975 0,08131608 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,03203975 0,0812304 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,03203975 0,08114489 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03203975 0,08105956 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,03203975 0,08097442 ! covalent chromatin modification GO:0016569 101 52 1,000 0,03235339 0,08168127 ! synapse organization GO:0050808 85 52 1,000 0,03235339 0,08159565 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 1,000 0,0335049 0,08441129 ! regulation of protein polymerization GO:0032271 103 53 1,000 0,0335049 0,08432299 ! response to UV GO:0009411 104 53 1,000 0,0335049 0,08423488 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 1,000 0,03467227 0,08707878 ! positive regulation of caspase activity GO:0043280 95 55 1,000 0,03585529 0,08995603 GO:0010952|positive regulation of peptidase activity, ! regulation of protein catabolic process GO:0042176 116 55 1,000 0,03585529 0,08986233 ! gastrulation GO:0007369 112 55 1,000 0,03585529 0,08976882 ! heart morphogenesis GO:0003007 97 55 1,000 0,03585529 0,0896755 ! regulation of multicellular organism growth GO:0040014 85 55 1,000 0,03585529 0,08958238 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,03705377 0,09248068 ! glycosaminoglycan metabolic process GO:0030203 91 56 1,000 0,03705377 0,09238485 ! tRNA transcription GO:0009304 14 7 0,000 0,03727962 0,09285171 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,03727962 0,09275569 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,03727962 0,09265987 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03727962 0,09256425 ! regulation of helicase activity GO:0051095 15 7 0,000 0,03727962 0,09246882 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,03727962 0,09237359 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,03727962 0,09227856 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03727962 0,09218372 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,03727962 0,09208907 ! prostate gland development GO:0030850 13 7 0,000 0,03727962 0,09199462 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,03727962 0,09190036 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03727962 0,0918063 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03727962 0,09171243 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,03727962 0,09161875 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03727962 0,09152526 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,03727962 0,09143196 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,03727962 0,09133886 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,03727962 0,09124594 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,03727962 0,09115321 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03727962 0,09106067 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,03727962 0,09096831 ! glycolipid transport GO:0046836 10 7 0,000 0,03727962 0,09087615 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03727962 0,09078417 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,03727962 0,09069237 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03727962 0,09060076 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,03727962 0,09050934 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03727962 0,0904181 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,03727962 0,09032705 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,03727962 0,09023617 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,03727962 0,09014548 ! pericardium development GO:0060039 14 7 0,000 0,03727962 0,09005498 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,03727962 0,08996465 GO:0031958|corticosteroid receptor signaling pathway, ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,03727962 0,0898745 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,03727962 0,08978454 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03727962 0,08969476 ! lipoprotein transport GO:0042953 14 7 0,000 0,03727962 0,08960515 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,03727962 0,08951572 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,03727962 0,08942648 ! rhythmic behavior GO:0007622 15 7 0,000 0,03727962 0,08933741 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,03727962 0,08924851 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,03727962 0,0891598 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,03727962 0,08907126 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03727962 0,08898289 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,03727962 0,0888947 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03727962 0,08880669 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,03727962 0,08871885 ! mechanosensory behavior GO:0007638 14 7 0,000 0,03727962 0,08863118 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,03727962 0,08854369 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,03727962 0,08845637 GO:0045911|positive regulation of DNA recombination, ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03727962 0,08836922 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03727962 0,08828224 ! spinal cord patterning GO:0021511 13 7 0,000 0,03727962 0,08819543 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,03727962 0,0881088 ! adrenal gland development GO:0030325 17 7 0,000 0,03727962 0,08802233 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,03727962 0,08793604 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,03727962 0,08784991 ! ovulation GO:0030728 9 7 0,000 0,03727962 0,08776395 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,03727962 0,08767816 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,03727962 0,08759254 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! microtubule nucleation GO:0007020 20 7 0,000 0,03727962 0,08750708 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03727962 0,08742179 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03727962 0,08733667 ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,03727962 0,08725171 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,03727962 0,08716692 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,03727962 0,08708229 ! galactose metabolic process GO:0006012 13 7 0,000 0,03727962 0,08699782 ! vesicle fusion GO:0006906 17 7 0,000 0,03727962 0,08691352 ! response to dietary excess GO:0002021 8 7 0,000 0,03727962 0,08682939 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03727962 0,08674541 ! intracellular pH reduction GO:0051452 11 7 0,000 0,03727962 0,0866616 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03727962 0,08657795 GO:0046464|acylglycerol catabolic process, ! organ growth GO:0035265 15 7 0,000 0,03727962 0,08649446 ! purine salvage GO:0043101 10 7 0,000 0,03727962 0,08641113 ! nucleoside transport GO:0015858 8 7 0,000 0,03727962 0,08632797 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,03727962 0,08624496 ! parturition GO:0007567 14 7 0,000 0,03727962 0,08616211 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,03727962 0,08607942 ! rRNA modification GO:0000154 14 7 0,000 0,03727962 0,08599689 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,03727962 0,08591452 ! spindle checkpoint GO:0031577 15 7 0,000 0,03727962 0,0858323 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,03727962 0,08575024 ! macrophage differentiation GO:0030225 11 7 0,000 0,03727962 0,08566834 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,03727962 0,0855866 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03727962 0,08550501 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,03727962 0,08542358 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,03727962 0,0853423 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,03727962 0,08526117 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03727962 0,08518021 ! eating behavior GO:0042755 7 7 0,000 0,03727962 0,08509939 ! B cell lineage commitment GO:0002326 21 7 0,000 0,03727962 0,08501873 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03727962 0,08493822 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,03727962 0,08485786 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,03727962 0,08477765 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03727962 0,0846976 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03727962 0,08461769 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,03727962 0,08453794 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,03727962 0,08445834 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,03727962 0,08437889 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03727962 0,08429958 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,03727962 0,08422043 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,03727962 0,08414142 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03727962 0,08406256 ! regulation of meiosis GO:0040020 12 7 0,000 0,03727962 0,08398385 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,03727962 0,08390529 ! T cell lineage commitment GO:0002360 16 7 0,000 0,03727962 0,08382687 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,03727962 0,0837486 GO:0002714|positive regulation of B cell mediated immunity, ! oxygen homeostasis GO:0032364 12 7 0,000 0,03727962 0,08367048 ! transcription termination GO:0006353 13 7 0,000 0,03727962 0,0835925 ! response to tumor cell GO:0002347 13 7 0,000 0,03727962 0,08351467 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,03727962 0,08343698 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03727962 0,08335944 ! anaphase GO:0051322 17 7 0,000 0,03727962 0,08328204 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,03727962 0,08320478 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,03727962 0,08312767 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,03727962 0,0830507 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,03727962 0,08297387 ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03727962 0,08289719 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03727962 0,08282064 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03727962 0,08274424 ! antibiotic transport GO:0042891 9 7 0,000 0,03727962 0,08266798 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03727962 0,08259186 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,03727962 0,08251587 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,03727962 0,08244003 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,03727962 0,08236433 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,03727962 0,08228877 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03727962 0,08221334 ! lymph node development GO:0048535 10 7 0,000 0,03727962 0,08213805 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,03727962 0,08206291 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,03727962 0,08198789 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,03727962 0,08191302 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,03727962 0,08183828 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,03727962 0,08176368 ! adult feeding behavior GO:0008343 9 7 0,000 0,03727962 0,08168921 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,03727962 0,08161488 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,03727962 0,08154069 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03727962 0,08146663 ! muscle adaptation GO:0043500 14 7 0,000 0,03727962 0,0813927 ! embryonic heart tube development GO:0035050 10 7 0,000 0,03727962 0,08131891 ! retina homeostasis GO:0001895 12 7 0,000 0,03727962 0,08124525 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,03727962 0,08117172 ! protein prenylation GO:0018342 18 7 0,000 0,03727962 0,08109833 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,03727962 0,08102507 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,03727962 0,08095195 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,03727962 0,08087895 ! muscle fiber development GO:0048747 112 57 1,000 0,03826751 0,08294741 ! lipid modification GO:0030258 97 57 1,000 0,03826751 0,08287275 ! regulation of intracellular transport GO:0032386 101 57 1,000 0,03826751 0,08279822 ! adult behavior GO:0030534 99 58 1,000 0,0394963 0,08538014 ! positive regulation of secretion GO:0051047 95 59 1,000 0,04073995 0,08798952 ! DNA catabolic process GO:0006308 86 59 1,000 0,04073995 0,08791061 ! establishment of organelle localization GO:0051656 109 59 1,000 0,04073995 0,08783184 ! kidney development GO:0001822 122 60 1,000 0,04199827 0,0904636 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,04249129 0,09144368 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,04249129 0,09136196 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,04249129 0,09128039 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,04249129 0,09119896 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04249129 0,09111768 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04249129 0,09103654 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,04249129 0,09095555 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,04249129 0,0908747 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,04249129 0,09079399 ! meiotic prophase I GO:0007128 13 8 0,000 0,04249129 0,09071343 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04249129 0,09063301 ! oligopeptide transport GO:0006857 15 8 0,000 0,04249129 0,09055273 ! UTP metabolic process GO:0046051 8 8 0,000 0,04249129 0,0904726 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,04249129 0,09039261 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,04249129 0,09031275 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,04249129 0,09023304 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04249129 0,09015347 ! succinate metabolic process GO:0006105 14 8 0,000 0,04249129 0,09007404 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,04249129 0,08999475 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,04249129 0,0899156 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,04249129 0,08983659 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04249129 0,08975771 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04249129 0,08967898 ! reflex GO:0060004 16 8 0,000 0,04249129 0,08960038 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,04249129 0,08952192 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04249129 0,0894436 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,04249129 0,08936542 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,04249129 0,08928737 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,04249129 0,08920946 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,04249129 0,08913168 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,04249129 0,08905404 ! histidine metabolic process GO:0006547 16 8 0,000 0,04249129 0,08897653 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04249129 0,08889916 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,04249129 0,08882193 ! glycine catabolic process GO:0006546 13 8 0,000 0,04249129 0,08874482 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,04249129 0,08866786 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,04249129 0,08859102 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,04249129 0,08851432 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,04249129 0,08843775 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,04249129 0,08836131 ! melanin metabolic process GO:0006582 15 8 0,000 0,04249129 0,08828501 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,04249129 0,08820883 ! macrophage activation GO:0042116 12 8 0,000 0,04249129 0,08813279 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,04249129 0,08805688 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,04249129 0,0879811 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,04249129 0,08790545 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,04249129 0,08782993 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,04249129 0,08775454 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,04249129 0,08767928 ! osteoblast development GO:0002076 16 8 0,000 0,04249129 0,08760414 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,04249129 0,08752914 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,04249129 0,08745427 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,04249129 0,08737952 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,04249129 0,0873049 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04249129 0,08723041 ! response to UV-B GO:0010224 16 8 0,000 0,04249129 0,08715604 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,04249129 0,0870818 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04249129 0,08700769 ! intermediate filament organization GO:0045109 12 8 0,000 0,04249129 0,0869337 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,04249129 0,08685984 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,04249129 0,08678611 ! cellular extravasation GO:0045123 12 8 0,000 0,04249129 0,0867125 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,04249129 0,08663901 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,04249129 0,08656565 ! response to antibiotic GO:0046677 11 8 0,000 0,04249129 0,08649242 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,04249129 0,0864193 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,04249129 0,08634632 ! DNA topological change GO:0006265 12 8 0,000 0,04249129 0,08627345 ! response to tropane GO:0014073 15 8 0,000 0,04249129 0,08620071 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,04249129 0,08612809 ! melanosome transport GO:0032402 13 8 0,000 0,04249129 0,08605559 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,04249129 0,08598321 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04249129 0,08591096 ! mast cell activation GO:0045576 14 8 0,000 0,04249129 0,08583882 ! multicellular organismal aging GO:0010259 18 8 0,000 0,04249129 0,08576681 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,04249129 0,08569492 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,04249129 0,08562315 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04249129 0,0855515 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04249129 0,08547996 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,04249129 0,08540855 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,04249129 0,08533726 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04249129 0,08526609 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,04249129 0,08519503 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,04249129 0,08512409 ! intracellular lipid transport GO:0032365 13 8 0,000 0,04249129 0,08505328 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04249129 0,08498257 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,04249129 0,08491199 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,04249129 0,08484152 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,04249129 0,08477118 ! hormone catabolic process GO:0042447 17 8 0,000 0,04249129 0,08470094 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04249129 0,08463083 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,04249129 0,08456082 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,04249129 0,08449094 ! ATP catabolic process GO:0006200 11 8 0,000 0,04249129 0,08442117 ! blastocyst growth GO:0001832 19 8 0,000 0,04249129 0,08435152 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,04249129 0,08428198 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,04249129 0,08421255 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04249129 0,08414324 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,04249129 0,08407404 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,04249129 0,08400496 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,04249129 0,08393599 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,04249129 0,08386713 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,04249129 0,08379839 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,04249129 0,08372976 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04249129 0,08366124 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,04249129 0,08359283 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04249129 0,08352454 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,04249129 0,08345636 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,04249129 0,08338828 ! regulation of protein complex assembly GO:0043254 117 61 1,000 0,04327107 0,08484938 ! sphingolipid metabolic process GO:0006665 107 61 1,000 0,04327107 0,08478028 ! gonad development GO:0008406 98 62 1,000 0,04455814 0,08723099 ! nucleoside monophosphate metabolic process GO:0009123 107 63 1,000 0,04585931 0,08970528 ! regulation of developmental growth GO:0048638 15 9 0,000 0,04767492 0,09318103 ! axon extension GO:0048675 15 9 0,000 0,04767492 0,0931054 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,04767492 0,09302989 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,04767492 0,0929545 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,04767492 0,09287923 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,04767492 0,09280409 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,04767492 0,09272906 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,04767492 0,09265416 ! phosphate transport GO:0006817 19 9 0,000 0,04767492 0,09257938 ! reproductive behavior GO:0019098 19 9 0,000 0,04767492 0,09250472 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,04767492 0,09243018 ! CTP metabolic process GO:0046036 9 9 0,000 0,04767492 0,09235576 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,04767492 0,09228146 ! GTP metabolic process GO:0046039 9 9 0,000 0,04767492 0,09220728 ! RNA methylation GO:0001510 15 9 0,000 0,04767492 0,09213321 ! elastic fiber assembly GO:0048251 15 9 0,000 0,04767492 0,09205927 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,04767492 0,09198545 ! artery development GO:0060840 24 9 0,000 0,04767492 0,09191174 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,04767492 0,09183815 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,04767492 0,09176468 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,04767492 0,09169133 ! chemosensory behavior GO:0007635 20 9 0,000 0,04767492 0,09161809 ! microtubule bundle formation GO:0001578 21 9 0,000 0,04767492 0,09154497 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,04767492 0,09147197 ! leukocyte degranulation GO:0043299 16 9 0,000 0,04767492 0,09139908 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,04767492 0,09132631 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,04767492 0,09125366 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,04767492 0,09118112 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,04767492 0,0911087 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,04767492 0,09103639 ! protein targeting to ER GO:0045047 22 9 0,000 0,04767492 0,0909642 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,04767492 0,09089212 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,04767492 0,09082015 ! T cell selection GO:0045058 23 9 0,000 0,04767492 0,0907483 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,04767492 0,09067656 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,04767492 0,09060494 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,04767492 0,09053343 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,04767492 0,09046203 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,04767492 0,09039074 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,04767492 0,09031957 ! mannose metabolic process GO:0006013 13 9 0,000 0,04767492 0,09024851 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,04767492 0,09017756 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,04767492 0,09010672 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,04767492 0,09003599 ! receptor clustering GO:0043113 18 9 0,000 0,04767492 0,08996537 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,04767492 0,08989487 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,04767492 0,08982447 ! retinol metabolic process GO:0042572 18 9 0,000 0,04767492 0,08975419 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,04767492 0,08968401 ! behavioral fear response GO:0001662 22 9 0,000 0,04767492 0,08961395 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,04767492 0,08954399 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,04767492 0,08947414 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,04767492 0,0894044 GO:0030204|chondroitin sulfate metabolic process, ! protein heterooligomerization GO:0051291 16 9 0,000 0,04767492 0,08933478 ! oligodendrocyte development GO:0014003 10 9 0,000 0,04767492 0,08926525 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,04767492 0,08919584 ! segment specification GO:0007379 13 9 0,000 0,04767492 0,08912654 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,04767492 0,08905734 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,04767492 0,08898825 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,04767492 0,08891926 ! response to amine stimulus GO:0014075 13 9 0,000 0,04767492 0,08885039 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,04767492 0,08878162 ! erythrocyte development GO:0048821 15 9 0,000 0,04767492 0,08871296 ! gas homeostasis GO:0033483 16 9 0,000 0,04767492 0,0886444 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,04767492 0,08857595 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,04767492 0,0885076 ! postreplication repair GO:0006301 22 9 0,000 0,04767492 0,08843936 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,04767492 0,08837123 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,04767492 0,0883032 ! icosanoid secretion GO:0032309 15 9 0,000 0,04767492 0,08823527 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,04767492 0,08816745 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,04767492 0,08809973 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,04767492 0,08803212 ! regulation of cell division GO:0051302 15 9 0,000 0,04767492 0,08796461 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,04767492 0,0878972 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,04767492 0,0878299 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,04767492 0,0877627 ! sterol catabolic process GO:0016127 11 9 0,000 0,04767492 0,0876956 GO:0006707|cholesterol catabolic process, ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,04767492 0,08762861 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,04767492 0,08756172 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,04767492 0,08749493 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,04767492 0,08742824 ! musculoskeletal movement GO:0050881 14 9 0,000 0,04767492 0,08736165 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,04767492 0,08729517 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,04767492 0,08722878 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,04767492 0,0871625 ! purine base metabolic process GO:0006144 21 9 0,000 0,04767492 0,08709632 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,04767492 0,08703024 ! pigment granule transport GO:0051904 17 9 0,000 0,04767492 0,08696425 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,04767492 0,08689837 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,04767492 0,08683259 ! mitochondrion localization GO:0051646 15 9 0,000 0,04767492 0,08676691 ! aminoglycan metabolic process GO:0006022 102 65 1,000 0,04850316 0,08820757 ! germ cell development GO:0007281 118 65 1,000 0,04850316 0,08814094 ! cell projection assembly GO:0030031 120 66 1,000 0,04984548 0,09051187 ! cellular hormone metabolic process GO:0034754 113 67 1,000 0,05120115 0,09290344 ! negative regulation of cell growth GO:0030308 132 67 1,000 0,05120115 0,09283343 ! adaptive immune response GO:0002250 119 67 1,000 0,05120115 0,09276353 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! membrane lipid metabolic process GO:0006643 117 68 1,000 0,05256999 0,09517185 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,05283066 0,09557185 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,05283066 0,09550004 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,05283066 0,09542835 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,05283066 0,09535676 ! synapsis GO:0007129 13 10 0,000 0,05283066 0,09528528 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,05283066 0,0952139 ! N-glycan processing GO:0006491 20 10 0,000 0,05283066 0,09514263 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,05283066 0,09507147 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,05283066 0,09500042 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,05283066 0,09492947 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,05283066 0,09485863 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,05283066 0,09478789 ! androgen metabolic process GO:0008209 17 10 0,000 0,05283066 0,09471726 ! phospholipid efflux GO:0033700 16 10 0,000 0,05283066 0,09464673 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,05283066 0,09457631 ! pathogenesis GO:0009405 13 10 0,000 0,05283066 0,09450599 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,05283066 0,09443578 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,05283066 0,09436567 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,05283066 0,09429567 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,05283066 0,09422577 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,05283066 0,09415597 ! endoderm development GO:0007492 16 10 0,000 0,05283066 0,09408628 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,05283066 0,09401669 ! arginine catabolic process GO:0006527 13 10 0,000 0,05283066 0,0939472 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,05283066 0,09387781 ! proline metabolic process GO:0006560 13 10 0,000 0,05283066 0,09380853 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,05283066 0,09373935 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,05283066 0,09367027 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,05283066 0,0936013 ! V(D)J recombination GO:0033151 28 10 0,000 0,05283066 0,09353242 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,05283066 0,09346365 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,05283066 0,09339497 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,05283066 0,0933264 ! B cell proliferation GO:0042100 18 10 0,000 0,05283066 0,09325793 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,05283066 0,09318956 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,05283066 0,09312129 ! multicellular organism growth GO:0035264 18 10 0,000 0,05283066 0,09305312 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,05283066 0,09298505 ! epithelial cell development GO:0002064 20 10 0,000 0,05283066 0,09291708 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,05283066 0,0928492 ! macroautophagy GO:0016236 17 10 0,000 0,05283066 0,09278143 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,05283066 0,09271376 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,05283066 0,09264618 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,05283066 0,0925787 ! copper ion homeostasis GO:0055070 13 10 0,000 0,05283066 0,09251132 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,05283066 0,09244404 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,05283066 0,09237686 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,05283066 0,09230977 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,05283066 0,09224279 ! blastoderm segmentation GO:0007350 18 10 0,000 0,05283066 0,09217589 ! response to dsRNA GO:0043331 20 10 0,000 0,05283066 0,0921091 ! DNA ligation GO:0006266 19 10 0,000 0,05283066 0,0920424 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,05283066 0,0919758 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,05283066 0,0919093 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,05283066 0,09184289 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,05283066 0,09177658 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,05283066 0,09171036 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,05283066 0,09164424 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,05283066 0,09157821 ! mRNA cleavage GO:0006379 17 10 0,000 0,05283066 0,09151228 ! protein sumoylation GO:0016925 15 10 0,000 0,05283066 0,09144645 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,05283066 0,0913807 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05283066 0,09131506 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,05283066 0,0912495 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,05283066 0,09118405 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,05283066 0,09111868 ! prophase GO:0051324 15 10 0,000 0,05283066 0,09105341 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,05283066 0,09098823 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,05283066 0,09092315 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,05283066 0,09085816 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,05283066 0,09079326 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,05283066 0,09072845 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,05283066 0,09066374 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,05283066 0,09059912 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,05283066 0,09053459 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,05283066 0,09047015 ! detection of calcium ion GO:0005513 23 10 0,000 0,05283066 0,0904058 ! oocyte development GO:0048599 17 10 0,000 0,05283066 0,09034155 ! blastocyst formation GO:0001825 17 10 0,000 0,05283066 0,09027739 ! cerebellar cortex development GO:0021695 15 10 0,000 0,05283066 0,09021331 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,05283066 0,09014933 ! activation of innate immune response GO:0002218 12 10 0,000 0,05283066 0,09008544 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,05283066 0,09002164 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,05283066 0,08995793 ! response to nicotine GO:0035094 20 10 0,000 0,05283066 0,08989431 ! establishment of cell polarity GO:0030010 16 10 0,000 0,05283066 0,08983078 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,05283066 0,08976734 ! negative regulation of cell size GO:0045792 134 69 1,000 0,05395181 0,09160766 ! urogenital system development GO:0001655 137 69 1,000 0,05395181 0,09154305 ! reproductive structure development GO:0048608 113 71 1,000 0,0567537 0,09622932 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,05795865 0,09820318 ! respiratory burst GO:0045730 17 11 0,000 0,05795865 0,09813407 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,05795865 0,09806506 ! neuron fate specification GO:0048665 17 11 0,000 0,05795865 0,09799615 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,05795865 0,09792733 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,05795865 0,09785861 ! thyroid gland development GO:0030878 26 11 0,000 0,05795865 0,09778999 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,05795865 0,09772146 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,05795865 0,09765303 ! response to pain GO:0048265 24 11 0,000 0,05795865 0,09758469 ! T cell proliferation GO:0042098 26 11 0,000 0,05795865 0,09751645 ! bone resorption GO:0045453 16 11 0,000 0,05795865 0,0974483 ! ventral spinal cord development GO:0021517 21 11 0,000 0,05795865 0,09738025 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,05795865 0,0973123 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,05795865 0,09724443 ! melanocyte differentiation GO:0030318 21 11 0,000 0,05795865 0,09717667 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,05795865 0,097109 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,05795865 0,09704142 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,05795865 0,09697394 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,05795865 0,09690655 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,05795865 0,09683925 ! lipid digestion GO:0044241 18 11 0,000 0,05795865 0,09677205 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,05795865 0,09670494 ! UV protection GO:0009650 19 11 0,000 0,05795865 0,09663792 ! adult heart development GO:0007512 14 11 0,000 0,05795865 0,096571 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,05795865 0,09650417 ! temperature homeostasis GO:0001659 17 11 0,000 0,05795865 0,09643743 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,05795865 0,09637078 ! negative regulation of ossification GO:0030279 26 11 0,000 0,05795865 0,09630423 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,05795865 0,09623776 ! regulation of organ growth GO:0046620 13 11 0,000 0,05795865 0,09617139 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,05795865 0,09610511 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,05795865 0,09603893 ! embryonic axis specification GO:0000578 18 11 0,000 0,05795865 0,09597283 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,05795865 0,09590682 ! snRNA metabolic process GO:0016073 24 11 0,000 0,05795865 0,09584091 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,05795865 0,09577508 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,05795865 0,09570935 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,05795865 0,0956437 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,05795865 0,09557815 ! zymogen activation GO:0031638 15 11 0,000 0,05795865 0,09551268 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,05795865 0,09544731 ! neuroblast proliferation GO:0007405 24 11 0,000 0,05795865 0,09538202 ! nucleosome positioning GO:0016584 15 11 0,000 0,05795865 0,09531683 ! regulation of isotype switching GO:0045191 22 11 0,000 0,05795865 0,09525172 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,05795865 0,0951867 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,05795865 0,09512177 ! acid secretion GO:0046717 18 11 0,000 0,05795865 0,09505693 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,05795865 0,09499218 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,05795865 0,09492752 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,05795865 0,09486294 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,05795865 0,09479845 ! oocyte differentiation GO:0009994 18 11 0,000 0,05795865 0,09473405 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,05795865 0,09466974 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,05795865 0,09460551 ! cholesterol efflux GO:0033344 19 11 0,000 0,05795865 0,09454137 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,05795865 0,09447732 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,05795865 0,09441335 ! germ cell migration GO:0008354 25 11 0,000 0,05795865 0,09434947 ! embryonic gut development GO:0048566 15 11 0,000 0,05795865 0,09428568 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,05795865 0,09422197 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,05795865 0,09415835 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,05795865 0,09409482 ! defense response to fungus GO:0050832 13 11 0,000 0,05795865 0,09403137 ! developmental induction GO:0031128 19 11 0,000 0,05795865 0,09396801 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,05795865 0,09390473 GO:0019047|provirus integration, ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,05795865 0,09384153 ! sequestering of metal ion GO:0051238 14 11 0,000 0,05795865 0,09377843 ! lamellipodium assembly GO:0030032 20 11 0,000 0,05795865 0,0937154 ! regulation of embryonic development GO:0045995 27 11 0,000 0,05795865 0,09365246 ! nucleus localization GO:0051647 19 11 0,000 0,05795865 0,09358961 ! regulation of synapse organization GO:0050807 17 11 0,000 0,05795865 0,09352684 ! regulation of blood pressure GO:0008217 125 73 1,000 0,05960541 0,09611972 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,06104952 0,09838254 GO:0090046|regulation of transcription regulator activity, ! organelle localization GO:0051640 136 74 1,000 0,06104952 0,09831669 ! cell-matrix adhesion GO:0007160 163 75 1,000 0,06250556 0,10059423 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 1,000 0,06250556 0,10052699 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,06305906 0,10134943 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,06305906 0,10128177 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,06305906 0,1012142 ! virus-host interaction GO:0019048 29 12 0,000 0,06305906 0,10114673 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,06305906 0,10107934 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,06305906 0,10101204 ! cartilage condensation GO:0001502 20 12 0,000 0,06305906 0,10094484 ! mating GO:0007618 17 12 0,000 0,06305906 0,10087772 ! protein complex disassembly GO:0043241 27 12 0,000 0,06305906 0,10081069 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,06305906 0,10074375 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,06305906 0,1006769 ! hippocampus development GO:0021766 26 12 0,000 0,06305906 0,10061014 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,06305906 0,10054347 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,06305906 0,10047688 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,06305906 0,10041038 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,06305906 0,10034397 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,06305906 0,10027765 ! drug transport GO:0015893 16 12 0,000 0,06305906 0,10021142 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,06305906 0,10014527 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,06305906 0,10007921 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,06305906 0,10001324 ! polyamine metabolic process GO:0006595 17 12 0,000 0,06305906 0,09994736 ! focal adhesion formation GO:0048041 35 12 0,000 0,06305906 0,09988156 ! mitotic spindle organization GO:0007052 21 12 0,000 0,06305906 0,09981585 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,06305906 0,09975022 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,06305906 0,09968468 ! entry into host cell GO:0030260 32 12 0,000 0,06305906 0,09961923 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,06305906 0,09955386 ! monoamine transport GO:0015844 18 12 0,000 0,06305906 0,09948858 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06305906 0,09942339 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,06305906 0,09935828 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,06305906 0,09929325 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,06305906 0,09922831 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,06305906 0,09916346 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,06305906 0,09909869 ! protein homotetramerization GO:0051289 21 12 0,000 0,06305906 0,099034 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,06305906 0,0989694 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,06305906 0,09890488 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,06305906 0,09884045 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,06305906 0,0987761 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,06305906 0,09871183 ! fucose catabolic process GO:0019317 22 12 0,000 0,06305906 0,09864765 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,06305906 0,09858355 ! histone methylation GO:0016571 26 12 0,000 0,06305906 0,09851954 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,06305906 0,09845561 ! T cell homeostasis GO:0043029 25 12 0,000 0,06305906 0,09839176 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,06305906 0,09832799 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,06305906 0,09826431 ! spleen development GO:0048536 22 12 0,000 0,06305906 0,09820071 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,06305906 0,09813719 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,06305906 0,09807375 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,06305906 0,09801039 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,06305906 0,09794712 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,06305906 0,09788393 ! response to cold GO:0009409 17 12 0,000 0,06305906 0,09782082 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,06305906 0,09775779 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,06305906 0,09769484 ! cytosolic calcium ion homeostasis GO:0051480 135 76 1,000 0,06397337 0,09904758 ! development of primary sexual characteristics GO:0045137 124 76 1,000 0,06397337 0,09898388 ! steroid biosynthetic process GO:0006694 131 76 1,000 0,06397337 0,09892026 ! response to steroid hormone stimulus GO:0048545 137 78 1,000 0,06694362 0,1034466 ! protein oligomerization GO:0051259 139 78 1,000 0,06694362 0,10338021 ! cGMP metabolic process GO:0046068 18 13 0,000 0,06813201 0,10514793 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,06813201 0,10508053 ! regulation of chemokine production GO:0032642 18 13 0,000 0,06813201 0,10501321 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,06813201 0,10494598 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,06813201 0,10487884 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,06813201 0,10481178 ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,06813201 0,10474481 ! organelle fusion GO:0048284 32 13 0,000 0,06813201 0,10467792 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,06813201 0,10461112 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,06813201 0,1045444 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,06813201 0,10447777 ! endocrine pancreas development GO:0031018 22 13 0,000 0,06813201 0,10441123 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,06813201 0,10434476 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,06813201 0,10427839 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,06813201 0,10421209 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,06813201 0,10414589 ! methionine metabolic process GO:0006555 27 13 0,000 0,06813201 0,10407976 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,06813201 0,10401372 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,06813201 0,10394776 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,06813201 0,10388189 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,06813201 0,1038161 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,06813201 0,1037504 ! response to X-ray GO:0010165 25 13 0,000 0,06813201 0,10368477 ! cytokine metabolic process GO:0042107 22 13 0,000 0,06813201 0,10361923 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,06813201 0,10355377 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,06813201 0,1034884 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,06813201 0,10342311 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,06813201 0,1033579 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,06813201 0,10329277 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,06813201 0,10322772 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,06813201 0,10316276 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,06813201 0,10309788 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,06813201 0,10303308 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,06813201 0,10296836 ! regulation of cellular pH GO:0030641 22 13 0,000 0,06813201 0,10290372 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,06813201 0,10283916 ! ribosome assembly GO:0042255 17 13 0,000 0,06813201 0,10277469 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,06813201 0,10271029 ! chromatin silencing GO:0006342 26 13 0,000 0,06813201 0,10264598 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,06813201 0,10258174 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,06813201 0,10251759 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,06813201 0,10245352 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,06813201 0,10238952 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,06813201 0,10232561 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,06813201 0,10226177 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,06813201 0,10219802 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,06813201 0,10213435 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,06813201 0,10207075 ! insulin secretion GO:0030073 23 13 0,000 0,06813201 0,10200723 ! actin filament polymerization GO:0030041 24 13 0,000 0,06813201 0,1019438 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,06813201 0,10188044 ! acrosome reaction GO:0007340 18 13 0,000 0,06813201 0,10181716 ! response to metal ion GO:0010038 140 80 1,000 0,06995895 0,10448245 ! cellular lipid catabolic process GO:0044242 134 80 1,000 0,06995895 0,10441764 ! protein import into nucleus GO:0006606 158 80 1,000 0,06995895 0,1043529 ! digestion GO:0007586 112 81 1,000 0,0714831 0,10656031 ! cell-substrate adhesion GO:0031589 171 81 1,000 0,0714831 0,10649433 ! nuclear import GO:0051170 161 81 1,000 0,0714831 0,10642843 ! regulation of cAMP biosynthetic process GO:0030817 161 82 1,000 0,07301804 0,10864651 ! rRNA transcription GO:0009303 25 14 0,000 0,07317767 0,10881674 ! lactation GO:0007595 26 14 0,000 0,07317767 0,10874952 ! reproductive cellular process GO:0048610 20 14 0,000 0,07317767 0,10868239 ! tRNA modification GO:0006400 20 14 0,000 0,07317767 0,10861535 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,07317767 0,10854838 ! regulation of S phase GO:0033261 23 14 0,000 0,07317767 0,1084815 ! water transport GO:0006833 21 14 0,000 0,07317767 0,1084147 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,07317767 0,10834799 ! non-recombinational repair GO:0000726 25 14 0,000 0,07317767 0,10828135 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,07317767 0,1082148 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,07317767 0,10814833 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,07317767 0,10808194 ! RNA polyadenylation GO:0043631 30 14 0,000 0,07317767 0,10801563 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,07317767 0,1079494 ! palate development GO:0060021 31 14 0,000 0,07317767 0,10788326 ! regulated secretory pathway GO:0045055 23 14 0,000 0,07317767 0,10781719 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,07317767 0,10775121 ! arginine metabolic process GO:0006525 17 14 0,000 0,07317767 0,10768531 ! organic alcohol transport GO:0015850 29 14 0,000 0,07317767 0,10761948 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,07317767 0,10755374 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,07317767 0,10748808 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,07317767 0,1074225 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,07317767 0,107357 ! neutral amino acid transport GO:0015804 26 14 0,000 0,07317767 0,10729158 ! L-amino acid transport GO:0015807 30 14 0,000 0,07317767 0,10722623 ! bone mineralization GO:0030282 17 14 0,000 0,07317767 0,10716097 ! stem cell development GO:0048864 43 14 0,000 0,07317767 0,10709579 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,07317767 0,10703069 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,07317767 0,10696566 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,07317767 0,10690071 ! cerebellum development GO:0021549 21 14 0,000 0,07317767 0,10683585 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,07317767 0,10677106 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,07317767 0,10670635 ! response to gamma radiation GO:0010332 28 14 0,000 0,07317767 0,10664172 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,07317767 0,10657717 ! cofactor transport GO:0051181 26 14 0,000 0,07317767 0,10651269 ! NADP metabolic process GO:0006739 24 14 0,000 0,07317767 0,10644829 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,07317767 0,10638397 ! intestinal absorption GO:0050892 25 14 0,000 0,07317767 0,10631973 ! oxygen transport GO:0015671 21 14 0,000 0,07317767 0,10625557 ! male genitalia development GO:0030539 24 14 0,000 0,07317767 0,10619148 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,07317767 0,10612747 ! regulation of cAMP metabolic process GO:0030814 168 84 1,000 0,07611961 0,11032758 ! negative regulation of growth GO:0045926 155 84 1,000 0,07611961 0,11026116 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,07768593 0,11246231 GO:0002696|positive regulation of leukocyte activation, ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,07819618 0,11313289 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,07819618 0,1130649 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! superoxide anion generation GO:0042554 20 15 0,000 0,07819618 0,112997 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,07819618 0,11292917 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,07819618 0,11286143 ! copper ion transport GO:0006825 20 15 0,000 0,07819618 0,11279376 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,07819618 0,11272618 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,07819618 0,11265868 ! sulfate transport GO:0008272 23 15 0,000 0,07819618 0,11259126 ! response to cAMP GO:0051591 22 15 0,000 0,07819618 0,11252392 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,07819618 0,11245666 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,07819618 0,11238949 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,07819618 0,11232239 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,07819618 0,11225537 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,07819618 0,11218843 ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,07819618 0,11212157 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,07819618 0,11205479 ! vesicle coating GO:0006901 33 15 0,000 0,07819618 0,11198809 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,07819618 0,11192147 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,07819618 0,11185493 ! regulation of exocytosis GO:0017157 22 15 0,000 0,07819618 0,11178847 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,07819618 0,11172209 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,07819618 0,11165579 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,07819618 0,11158956 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,07819618 0,11152341 ! regulation of vasodilation GO:0042312 26 15 0,000 0,07819618 0,11145735 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,07819618 0,11139136 ! histone deacetylation GO:0016575 20 15 0,000 0,07819618 0,11132544 ! mRNA splice site selection GO:0006376 38 15 0,000 0,07819618 0,11125961 ! tissue regeneration GO:0042246 26 15 0,000 0,07819618 0,11119385 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,07819618 0,11112817 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,07819618 0,11106257 ! muscle maintenance GO:0046716 26 15 0,000 0,07819618 0,11099705 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,07819618 0,1109316 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,07819618 0,11086623 ! heme biosynthetic process GO:0006783 29 15 0,000 0,07819618 0,11080094 ! cell killing GO:0001906 29 15 0,000 0,07819618 0,11073573 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,07819618 0,11067059 ! detection of bacterium GO:0016045 18 15 0,000 0,07819618 0,11060553 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,07819618 0,11054054 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,07819618 0,11047563 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,07819618 0,1104108 ! peptide hormone processing GO:0016486 23 15 0,000 0,07819618 0,11034604 ! amine biosynthetic process GO:0009309 138 86 1,000 0,0792624 0,11178508 ! response to inorganic substance GO:0010035 153 86 1,000 0,0792624 0,11171959 ! mitochondrion organization GO:0007005 148 86 1,000 0,0792624 0,11165418 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 1,000 0,08084887 0,11382234 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! protein localization in nucleus GO:0034504 176 87 1,000 0,08084887 0,11375578 ! regulation of DNA binding GO:0051101 155 88 1,000 0,08244518 0,11593402 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,08318767 0,11690978 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,08318767 0,11684153 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,08318767 0,11677336 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,08318767 0,11670527 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,08318767 0,11663726 ! bone remodeling GO:0046849 27 16 0,000 0,08318767 0,11656933 ! filopodium assembly GO:0046847 32 16 0,000 0,08318767 0,11650148 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,08318767 0,11643371 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,08318767 0,11636601 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,08318767 0,1162984 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,08318767 0,11623086 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,08318767 0,1161634 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,08318767 0,11609602 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,08318767 0,11602872 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,08318767 0,11596149 ! protein polyubiquitination GO:0000209 34 16 0,000 0,08318767 0,11589435 ! glutamate metabolic process GO:0006536 22 16 0,000 0,08318767 0,11582728 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,08318767 0,11576029 ! response to osmotic stress GO:0006970 25 16 0,000 0,08318767 0,11569338 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,08318767 0,11562654 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,08318767 0,11555978 ! fructose metabolic process GO:0006000 25 16 0,000 0,08318767 0,1154931 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,08318767 0,11542649 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 32 16 0,000 0,08318767 0,11535996 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,08318767 0,11529351 ! axon cargo transport GO:0008088 43 16 0,000 0,08318767 0,11522714 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,08318767 0,11516084 ! DNA replication initiation GO:0006270 27 16 0,000 0,08318767 0,11509462 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,08318767 0,11502847 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,08318767 0,1149624 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,08318767 0,11489641 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,08318767 0,11483049 ! biomineral formation GO:0031214 20 16 0,000 0,08318767 0,11476464 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,08318767 0,11469888 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,08318767 0,11463318 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,08318767 0,11456757 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,08318767 0,11450202 ! defense response to virus GO:0051607 37 16 0,000 0,08318767 0,11443656 ! cellular defense response GO:0006968 114 89 1,000 0,08405119 0,11555837 ! ossification GO:0001503 188 90 1,000 0,08566673 0,11771225 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 1,000 0,08566673 0,11764506 ! sex differentiation GO:0007548 145 90 1,000 0,08566673 0,11757795 ! bone development GO:0060348 189 91 1,000 0,08729166 0,11973988 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,0881523 0,12085154 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,0881523 0,12078271 ! metencephalon development GO:0022037 30 17 0,000 0,0881523 0,12071397 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,0881523 0,1206453 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,0881523 0,12057672 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,0881523 0,12050821 ! signal complex assembly GO:0007172 41 17 0,000 0,0881523 0,12043978 ! inositol metabolic process GO:0006020 28 17 0,000 0,0881523 0,12037142 ! gene silencing by RNA GO:0031047 36 17 0,000 0,0881523 0,12030315 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,0881523 0,12023495 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,0881523 0,12016682 ! heart looping GO:0001947 30 17 0,000 0,0881523 0,12009878 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,0881523 0,12003081 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,0881523 0,11996292 ! myoblast differentiation GO:0045445 45 17 0,000 0,0881523 0,11989511 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,0881523 0,11982737 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,0881523 0,11975971 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,0881523 0,11969213 ! glycine metabolic process GO:0006544 28 17 0,000 0,0881523 0,11962462 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,0881523 0,11955718 ! NAD metabolic process GO:0019674 29 17 0,000 0,0881523 0,11948983 ! membrane budding GO:0006900 37 17 0,000 0,0881523 0,11942255 ! DNA integration GO:0015074 29 17 0,000 0,0881523 0,11935534 ! regulation of protein binding GO:0043393 33 17 0,000 0,0881523 0,11928821 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,0881523 0,11922116 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,0881523 0,11915418 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,0881523 0,11908728 ! genitalia development GO:0048806 30 17 0,000 0,0881523 0,11902045 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,0881523 0,1189537 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,0881523 0,11888702 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,0881523 0,11882042 ! steroid catabolic process GO:0006706 31 17 0,000 0,0881523 0,11875389 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,0881523 0,11868743 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,0881523 0,11862105 ! gas transport GO:0015669 25 17 0,000 0,0881523 0,11855475 ! organic cation transport GO:0015695 31 17 0,000 0,0881523 0,11848852 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,0881523 0,11842236 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,0881523 0,11835628 ! microspike assembly GO:0030035 36 17 0,000 0,0881523 0,11829027 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,0881523 0,11822433 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,0881523 0,11815847 ! regulation of nucleotide metabolic process GO:0006140 182 93 1,000 0,09056913 0,12133035 ! biogenic amine metabolic process GO:0006576 155 94 1,000 0,09222136 0,12347501 ! female pregnancy GO:0007565 164 94 1,000 0,09222136 0,12340634 ! regulation of T cell activation GO:0050863 158 94 1,000 0,09222136 0,12333774 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,09309022 0,12443059 ! neuron maturation GO:0042551 42 18 0,000 0,09309022 0,1243615 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,09309022 0,12429249 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,09309022 0,12422355 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,09309022 0,12415469 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,09309022 0,12408591 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,09309022 0,1240172 ! memory GO:0007613 31 18 0,000 0,09309022 0,12394857 ! negative regulation of ion transport GO:0043271 24 18 0,000 0,09309022 0,12388001 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,09309022 0,12381153 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,09309022 0,12374313 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,09309022 0,1236748 ! glutamine metabolic process GO:0006541 29 18 0,000 0,09309022 0,12360655 ! response to retinoic acid GO:0032526 26 18 0,000 0,09309022 0,12353837 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,09309022 0,12347027 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,09309022 0,12340224 ! response to fungus GO:0009620 21 18 0,000 0,09309022 0,12333429 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,09309022 0,12326641 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,09309022 0,1231986 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,09309022 0,12313088 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,09309022 0,12306322 ! vitamin transport GO:0051180 27 18 0,000 0,09309022 0,12299564 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,09309022 0,12292814 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,09309022 0,1228607 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,09309022 0,12279335 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,09309022 0,12272606 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,09309022 0,12265885 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,09309022 0,12259172 ! interphase of mitotic cell cycle GO:0051329 209 95 1,000 0,0938824 0,12356732 ! positive regulation of immune response GO:0050778 156 96 1,000 0,09555212 0,12569622 ! regulation of DNA metabolic process GO:0051052 178 97 1,000 0,09723036 0,12783401 ! hormone metabolic process GO:0042445 157 97 1,000 0,09723036 0,12776419 ! protein secretion GO:0009306 39 19 0,000 0,09800155 0,12870728 ! negative regulation of defense response GO:0031348 25 19 0,000 0,09800155 0,12863706 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,09800155 0,12856692 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,09800155 0,12849686 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,09800155 0,12842687 ! bile acid metabolic process GO:0008206 29 19 0,000 0,09800155 0,12835696 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,09800155 0,12828713 ! pigmentation during development GO:0048066 41 19 0,000 0,09800155 0,12821737 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,09800155 0,12814768 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,09800155 0,12807808 ! heme metabolic process GO:0042168 36 19 0,000 0,09800155 0,12800854 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,09800155 0,12793909 ! plasma membrane fusion GO:0045026 28 19 0,000 0,09800155 0,12786971 ! protein export from nucleus GO:0006611 36 19 0,000 0,09800155 0,1278004 ! heart process GO:0003015 30 19 0,000 0,09800155 0,12773117 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,09800155 0,12766201 GO:0006692|prostanoid metabolic process, ! visual learning GO:0008542 36 19 0,000 0,09800155 0,12759293 ! G1 phase GO:0051318 40 19 0,000 0,09800155 0,12752393 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,09800155 0,12745499 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,09800155 0,12738614 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,09800155 0,12731735 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,09800155 0,12724864 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,09800155 0,12718001 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,09800155 0,12711145 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,09800155 0,12704296 ! cilium assembly GO:0042384 37 19 0,000 0,09800155 0,12697455 ! response to virus GO:0009615 160 98 1,000 0,09891698 0,12809164 ! interphase GO:0051325 213 98 1,000 0,09891698 0,12802273 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,10288645 0,13308861 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,10288645 0,13301709 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,10288645 0,13294565 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,10288645 0,13287429 ! response to vitamin GO:0033273 31 20 0,000 0,10288645 0,13280301 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,10288645 0,1327318 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,10288645 0,13266067 ! retinoid metabolic process GO:0001523 32 20 0,000 0,10288645 0,13258961 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,10288645 0,13251863 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,10288645 0,13244773 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,10288645 0,1323769 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,10288645 0,13230615 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,10288645 0,13223547 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,10288645 0,13216487 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,10288645 0,13209435 ! stem cell differentiation GO:0048863 53 20 0,000 0,10288645 0,1320239 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,10288645 0,13195352 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,10288645 0,13188322 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,10288645 0,131813 ! sensory perception of pain GO:0019233 30 20 0,000 0,10288645 0,13174285 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,10288645 0,13167277 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,10288645 0,13160277 GO:0006626|protein targeting to mitochondrion, ! detection of chemical stimulus GO:0009593 37 20 0,000 0,10288645 0,13153284 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,10288645 0,13146299 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,10288645 0,13139321 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,10288645 0,13132351 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,10288645 0,13125388 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,10288645 0,13118432 ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,10288645 0,13111484 ! actin filament-based movement GO:0030048 43 20 0,000 0,10288645 0,13104543 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,10288645 0,13097609 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,10288645 0,13090683 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,10288645 0,13083764 ! regulation of cell killing GO:0031341 42 21 0,000 0,10774506 0,1369438 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,10774506 0,1368715 ! glycerol metabolic process GO:0006071 34 21 0,000 0,10774506 0,13679927 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,10774506 0,13672712 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,10774506 0,13665504 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,10774506 0,13658304 ! axis specification GO:0009798 38 21 0,000 0,10774506 0,13651112 ! ovarian follicle development GO:0001541 35 21 0,000 0,10774506 0,13643927 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,10774506 0,1363675 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,10774506 0,1362958 ! cell aging GO:0007569 44 21 0,000 0,10774506 0,13622418 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,10774506 0,13615264 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,10774506 0,13608116 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,10774506 0,13600977 ! cytolysis GO:0019835 24 21 0,000 0,10774506 0,13593845 ! vasodilation GO:0042311 39 21 0,000 0,10774506 0,1358672 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,10774506 0,13579603 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,10774506 0,13572493 ! oogenesis GO:0048477 36 21 0,000 0,10774506 0,13565391 ! DNA modification GO:0006304 34 21 0,000 0,10774506 0,13558296 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,10774506 0,13551208 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,10774506 0,13544128 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,10774506 0,13537056 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,10774506 0,13529991 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,10774506 0,13522933 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,10774506 0,13515882 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,10774506 0,13508839 ! collagen catabolic process GO:0030574 28 21 0,000 0,10774506 0,13501803 ! sperm-egg recognition GO:0035036 21 21 0,000 0,10774506 0,13494775 ! gut development GO:0048565 39 21 0,000 0,10774506 0,13487753 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,11257752 0,14085362 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,11257752 0,14078041 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,11257752 0,14070727 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,11257752 0,14063422 ! microtubule-based transport GO:0010970 54 22 0,000 0,11257752 0,14056124 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,11257752 0,14048833 ! regeneration GO:0031099 41 22 0,000 0,11257752 0,1404155 ! keratinization GO:0031424 28 22 0,000 0,11257752 0,14034275 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,11257752 0,14027007 ! sensory perception of taste GO:0050909 28 22 0,000 0,11257752 0,14019747 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,11257752 0,14012494 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,11257752 0,14005248 ! vacuolar transport GO:0007034 36 22 0,000 0,11257752 0,13998011 ! central nervous system neuron development GO:0021954 46 22 0,000 0,11257752 0,1399078 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,11257752 0,13983557 ! fucose metabolic process GO:0006004 39 22 0,000 0,11257752 0,13976342 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,11257752 0,13969134 ! ureteric bud development GO:0001657 43 22 0,000 0,11257752 0,13961933 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,11257752 0,1395474 GO:0060415|muscle tissue morphogenesis, ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,11257752 0,13947554 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,11257752 0,13940376 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,11257752 0,13933205 ! sarcomere organization GO:0045214 30 22 0,000 0,11257752 0,13926041 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,11257752 0,13918885 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,11257752 0,13911736 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,11257752 0,13904595 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,11257752 0,1389746 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,11257752 0,13890334 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,11257752 0,13883214 ! protein stabilization GO:0050821 39 22 0,000 0,11257752 0,13876102 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,11738396 0,14461127 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,11738396 0,14453726 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,11738396 0,14446333 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,11738396 0,14438947 ! gluconeogenesis GO:0006094 33 23 0,000 0,11738396 0,14431569 ! viral genome replication GO:0019079 41 23 0,000 0,11738396 0,14424198 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,11738396 0,14416835 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,11738396 0,1440948 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,11738396 0,14402132 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,11738396 0,14394791 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,11738396 0,14387458 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,11738396 0,14380133 ! visual behavior GO:0007632 42 23 0,000 0,11738396 0,14372814 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,11738396 0,14365504 ! response to ethanol GO:0045471 46 23 0,000 0,11738396 0,143582 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,11738396 0,14350905 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,11738396 0,14343616 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,11738396 0,14336335 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,11738396 0,14329062 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,11738396 0,14321795 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,11738396 0,14314536 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,11738396 0,14307285 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,11738396 0,14300041 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,11738396 0,14292804 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,11738396 0,14285574 ! fatty acid transport GO:0015908 44 23 0,000 0,11738396 0,14278352 ! platelet activation GO:0030168 37 23 0,000 0,11738396 0,14271137 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,11738396 0,14263929 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,11738396 0,14256729 ! cell-cell recognition GO:0009988 25 23 0,000 0,11738396 0,14249536 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,11738396 0,1424235 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,11738396 0,14235172 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,11738396 0,14228 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,12216453 0,14799992 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,12216453 0,14792544 GO:0016444|somatic cell DNA recombination, ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,12216453 0,14785103 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,12216453 0,1477767 ! vesicle docking GO:0048278 47 24 0,000 0,12216453 0,14770244 ! spinal cord development GO:0021510 47 24 0,000 0,12216453 0,14762825 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,12216453 0,14755414 ! digestive system process GO:0022600 39 24 0,000 0,12216453 0,14748011 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,12216453 0,14740614 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,12216453 0,14733226 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,12216453 0,14725844 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,12216453 0,1471847 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,12216453 0,14711104 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,12216453 0,14703744 ! pentose metabolic process GO:0019321 35 24 0,000 0,12216453 0,14696392 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,12216453 0,14689048 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,12216453 0,14681711 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,12216453 0,14674381 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,12216453 0,14667058 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,12216453 0,14659743 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,12216453 0,14652435 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,12216453 0,14645135 ! regulation of amine transport GO:0051952 40 24 0,000 0,12216453 0,14637841 ! protein tetramerization GO:0051262 52 24 0,000 0,12216453 0,14630555 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,12691936 0,15192437 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,12691936 0,15184882 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,12691936 0,15177335 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,12691936 0,15169795 ! phototransduction GO:0007602 33 25 0,000 0,12691936 0,15162263 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,12691936 0,15154738 GO:0006479|protein amino acid methylation, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,12691936 0,15147221 ! sperm motility GO:0030317 31 25 0,000 0,12691936 0,15139711 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,12691936 0,15132209 ! chromosome condensation GO:0030261 45 25 0,000 0,12691936 0,15124714 ! response to starvation GO:0042594 42 25 0,000 0,12691936 0,15117227 ! osteoblast differentiation GO:0001649 60 25 0,000 0,12691936 0,15109747 ! response to endoplasmic reticulum stress GO:0034976 43 25 0,000 0,12691936 0,15102274 ! coenzyme catabolic process GO:0009109 39 25 0,000 0,12691936 0,15094809 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,12691936 0,15087351 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,12691936 0,150799 ! interaction with host GO:0051701 62 25 0,000 0,12691936 0,15072457 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,12691936 0,15065021 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,12691936 0,15057593 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,12691936 0,15050171 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,12691936 0,15042758 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,12691936 0,15035351 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,12691936 0,15027952 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,12691936 0,1502056 ! telomere organization GO:0032200 43 25 0,000 0,12691936 0,15013175 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,12691936 0,15005797 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,12691936 0,14998427 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,13164859 0,15549657 ! embryonic pattern specification GO:0009880 44 26 0,000 0,13164859 0,15542027 ! initiation of viral infection GO:0019059 57 26 0,000 0,13164859 0,15534405 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,13164859 0,1552679 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,13164859 0,15519183 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,13164859 0,15511583 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,13164859 0,1550399 ! tube lumen formation GO:0035148 50 26 0,000 0,13164859 0,15496405 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,13164859 0,15488827 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,13164859 0,15481257 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,13164859 0,15473694 GO:0051297|centrosome organization, ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,13164859 0,15466139 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,13164859 0,1545859 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,13164859 0,1545105 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,13164859 0,15443516 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,13164859 0,1543599 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,13164859 0,15428471 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,13164859 0,1542096 ! blastocyst development GO:0001824 49 26 0,000 0,13164859 0,15413456 ! leukocyte proliferation GO:0070661 52 26 0,000 0,13164859 0,15405959 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,13164859 0,15398469 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,13635237 0,15940904 ! neuron fate commitment GO:0048663 48 27 0,000 0,13635237 0,15933162 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,13635237 0,15925427 ! iron ion transport GO:0006826 59 27 0,000 0,13635237 0,159177 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,13635237 0,15909981 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,13635237 0,15902268 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,13635237 0,15894564 ! fat cell differentiation GO:0045444 50 27 0,000 0,13635237 0,15886867 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,13635237 0,15879177 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,13635237 0,15871495 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,13635237 0,1586382 ! autophagy GO:0006914 41 27 0,000 0,13635237 0,15856153 ! response to toxin GO:0009636 47 27 0,000 0,13635237 0,15848493 ! primary neural tube formation GO:0014020 51 27 0,000 0,13635237 0,1584084 ! base-excision repair GO:0006284 41 27 0,000 0,13635237 0,15833195 ! glutathione metabolic process GO:0006749 39 27 0,000 0,13635237 0,15825557 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,13635237 0,15817927 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,13635237 0,15810304 ! circadian rhythm GO:0007623 50 28 0,000 0,14103082 0,16344901 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,14103082 0,16337032 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,14103082 0,1632917 ! ER-nuclear signaling pathway GO:0006984 48 28 0,000 0,14103082 0,16321316 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,14103082 0,16313469 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,14103082 0,16305629 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,14103082 0,16297798 ! synaptogenesis GO:0007416 42 28 0,000 0,14103082 0,16289974 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,14103082 0,16282157 ! lipid oxidation GO:0034440 43 28 0,000 0,14103082 0,16274348 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,14103082 0,16266546 ! translational initiation GO:0006413 65 29 0,000 0,14568408 0,16795203 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,14568408 0,1678716 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,14568408 0,16779124 ! complement activation, classical pathway GO:0006958 48 29 0,000 0,14568408 0,16771096 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,14568408 0,16763075 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,14568408 0,16755062 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,14568408 0,16747057 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,14568408 0,16739059 ! cell fate determination GO:0001709 60 29 0,000 0,14568408 0,16731069 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,14568408 0,16723087 ! detection of light stimulus GO:0009583 38 29 0,000 0,14568408 0,16715112 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 0,14568408 0,16707145 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,14568408 0,16699185 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,14568408 0,16691233 ! tissue homeostasis GO:0001894 48 29 0,000 0,14568408 0,16683289 GO:0048871|multicellular organismal homeostasis, ! zinc ion transport GO:0006829 45 30 0,000 0,15031229 0,17205108 ! membrane docking GO:0022406 61 30 0,000 0,15031229 0,17196926 ! cell junction assembly GO:0034329 78 30 0,000 0,15031229 0,17188753 ! regulation of innate immune response GO:0045088 51 30 0,000 0,15031229 0,17180587 ! acute-phase response GO:0006953 49 30 0,000 0,15031229 0,17172429 ! myofibril assembly GO:0030239 47 30 0,000 0,15031229 0,17164279 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,15031229 0,17156137 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,15031229 0,17148002 ! phospholipid transport GO:0015914 51 30 0,000 0,15031229 0,17139875 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,15031229 0,17131756 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,15031229 0,17123644 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,15031229 0,1711554 ! regulation of B cell activation GO:0050864 50 30 0,000 0,15031229 0,17107444 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,15491557 0,1762302 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,15491557 0,17614691 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,15491557 0,17606371 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,15491557 0,17598058 GO:0009799|determination of symmetry, ! inner ear morphogenesis GO:0042472 47 31 0,000 0,15491557 0,17589753 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,15491557 0,17581456 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,15491557 0,17573167 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,15491557 0,17564886 ! ovulation cycle process GO:0022602 49 31 0,000 0,15491557 0,17556612 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,15491557 0,17548346 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,15491557 0,17540088 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,15491557 0,17531838 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,15491557 0,17523595 ! mesoderm formation GO:0001707 69 31 0,000 0,15491557 0,1751536 ! natural killer cell activation GO:0030101 45 31 0,000 0,15491557 0,17507133 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,15491557 0,17498914 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,15491557 0,17490703 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,15491557 0,17482499 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,15491557 0,17474302 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,15491557 0,17466114 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,15949407 0,17973899 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,15949407 0,17965484 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,15949407 0,17957077 ! cholesterol transport GO:0030301 56 32 0,000 0,15949407 0,17948678 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,15949407 0,17940287 ! spliceosome assembly GO:0000245 67 32 0,000 0,15949407 0,17931904 ! spindle organization GO:0007051 46 32 0,000 0,15949407 0,17923528 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,15949407 0,17915161 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,15949407 0,17906801 ! response to ionizing radiation GO:0010212 65 32 0,000 0,15949407 0,17898449 ! muscle cell development GO:0055001 49 32 0,000 0,15949407 0,17890105 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,15949407 0,17881768 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,15949407 0,17873439 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,15949407 0,17865118 ! ovulation cycle GO:0042698 51 32 0,000 0,15949407 0,17856805 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,15949407 0,178485 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,15949407 0,17840202 ! gene silencing GO:0016458 65 32 0,000 0,15949407 0,17831912 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,16404792 0,18332527 ! post-embryonic development GO:0009791 69 33 0,000 0,16404792 0,18324016 ! protein targeting to membrane GO:0006612 68 33 0,000 0,16404792 0,18315513 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,16404792 0,18307017 ! formation of primary germ layer GO:0001704 72 33 0,000 0,16404792 0,1829853 ! cell fate specification GO:0001708 52 33 0,000 0,16404792 0,18290051 ! sterol transport GO:0015918 57 33 0,000 0,16404792 0,18281579 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,16404792 0,18273116 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,16404792 0,1826466 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,16857724 0,18760261 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,16857724 0,18751588 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,16857724 0,18742923 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,16857724 0,18734266 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,16857724 0,18725616 ! mismatch repair GO:0006298 46 34 0,000 0,16857724 0,18716975 ! spermatid development GO:0007286 63 34 0,000 0,16857724 0,18708342 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,16857724 0,18699717 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,16857724 0,18691099 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,17308218 0,19181747 ! odontogenesis GO:0042476 66 35 0,000 0,17308218 0,19172915 ! female gonad development GO:0008585 58 35 0,000 0,17308218 0,19164092 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,17308218 0,19155277 GO:0006639|acylglycerol metabolic process, ! cytokine production GO:0001816 59 35 0,000 0,17308218 0,1914647 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,17308218 0,19137671 ! neural tube formation GO:0001841 67 35 0,000 0,17308218 0,1912888 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,17756285 0,1961507 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,17756285 0,19606068 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,17756285 0,19597074 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,17756285 0,19588089 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,17756285 0,19579112 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,17756285 0,19570143 ! aerobic respiration GO:0009060 55 36 0,000 0,17756285 0,19561182 ! embryonic organ development GO:0048568 57 36 0,000 0,17756285 0,1955223 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,17756285 0,19543285 ! RNA export from nucleus GO:0006405 56 37 0,000 0,18201939 0,2002463 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,18201939 0,20015478 ! meiosis I GO:0007127 65 37 0,000 0,18201939 0,20006334 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,18201939 0,19997199 ! sister chromatid segregation GO:0000819 58 37 0,000 0,18201939 0,19988072 ! actomyosin structure organization GO:0031032 62 37 0,000 0,18201939 0,19978954 ! organic anion transport GO:0015711 68 37 0,000 0,18201939 0,19969843 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,18201939 0,19960741 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,18201939 0,19951647 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,18201939 0,19942562 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 61 37 0,000 0,18201939 0,19933485 ! pigment metabolic process GO:0042440 80 37 0,000 0,18201939 0,19924416 ! spermatid differentiation GO:0048515 66 37 0,000 0,18201939 0,19915355 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,18645193 0,20391062 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,18645193 0,20381797 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,18645193 0,20372541 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,18645193 0,20363293 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,18645193 0,20354054 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,18645193 0,20344823 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,18645193 0,20335601 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 67 38 0,000 0,18645193 0,20326387 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,18645193 0,20317181 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,18645193 0,20307983 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,18645193 0,20298794 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,18645193 0,20289614 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,18645193 0,20280441 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! glucan metabolic process GO:0044042 62 38 0,000 0,18645193 0,20271277 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,1908606 0,2074122 ! learning GO:0007612 77 39 0,000 0,1908606 0,20731856 ! organic ether metabolic process GO:0018904 55 39 0,000 0,1908606 0,20722501 ! ion transmembrane transport GO:0034220 66 39 0,000 0,1908606 0,20713153 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,1908606 0,20703815 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,1908606 0,20694485 ! RNA modification GO:0009451 57 39 0,000 0,1908606 0,20685163 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,19524553 0,21150866 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,19524553 0,21141347 ! feeding behavior GO:0007631 59 40 0,000 0,19524553 0,21131837 ! negative regulation of binding GO:0051100 72 40 0,000 0,19524553 0,21122335 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,19524553 0,21112842 ! maintenance of protein location GO:0045185 91 40 0,000 0,19524553 0,21103357 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,19960683 0,21565067 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,19960683 0,21555388 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,19960683 0,21545717 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,19960683 0,21536055 ! T cell differentiation GO:0030217 81 41 0,000 0,19960683 0,21526402 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,19960683 0,21516758 ! female gamete generation GO:0007292 61 41 0,000 0,19960683 0,21507122 ! polyol metabolic process GO:0019751 66 41 0,000 0,19960683 0,21497495 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,20394465 0,21954846 ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,20394465 0,21945028 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,20394465 0,21935218 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,20394465 0,21925416 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,20394465 0,21915624 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,20825909 0,22369258 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,20825909 0,22359276 ! neural tube development GO:0021915 77 43 0,000 0,20825909 0,22349303 ! striated muscle contraction GO:0006941 77 43 0,000 0,20825909 0,22339339 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,20825909 0,22329384 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,2125503 0,22779333 ! double-strand break repair GO:0006302 81 44 0,000 0,2125503 0,22769191 ! biopolymer methylation GO:0043414 84 44 0,000 0,2125503 0,22759058 ! B cell differentiation GO:0030183 107 44 0,000 0,2125503 0,22748933 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,2125503 0,22738818 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,2125503 0,22728712 ! developmental growth GO:0048589 82 44 0,000 0,2125503 0,22718615 ! maintenance of location in cell GO:0051651 97 44 0,000 0,2125503 0,22708527 ! glycolysis GO:0006096 65 45 0,000 0,21681839 0,23154241 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,21681839 0,23143969 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,21681839 0,23133705 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,21681839 0,23123451 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,21681839 0,23113206 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,21681839 0,23102969 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,21681839 0,23092742 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,22106349 0,23534458 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,22106349 0,23524049 ! endosome transport GO:0016197 108 47 0,000 0,22528572 0,23962752 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,22528572 0,23952163 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,22528572 0,23941583 ! JNK cascade GO:0007254 91 47 0,000 0,22528572 0,23931013 ! methylation GO:0032259 90 47 0,000 0,22528572 0,23920452 ! mitochondrial transport GO:0006839 82 48 0,000 0,2294852 0,24355597 ! Notch signaling pathway GO:0007219 96 48 0,000 0,2294852 0,24344859 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,2294852 0,24334129 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,2294852 0,24323409 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,2294852 0,24312699 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,23366206 0,24744318 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,23366206 0,24733432 ! regulation of ion transport GO:0043269 77 49 0,000 0,23366206 0,24722556 ! peptide metabolic process GO:0006518 76 49 0,000 0,23366206 0,24711688 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,23366206 0,24700831 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,23366206 0,24689983 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,23366206 0,24679145 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,23366206 0,24668316 ! inner ear development GO:0048839 79 50 0,000 0,23781641 0,2509589 ! viral infectious cycle GO:0019058 99 51 0,000 0,24194838 0,25520728 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,24194838 0,25509544 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,24194838 0,25498371 ! chromatin remodeling GO:0006338 109 51 0,000 0,24194838 0,25487207 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,24194838 0,25476053 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,24194838 0,25464908 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,24194838 0,25453774 ! membrane fusion GO:0006944 110 52 0,000 0,24605809 0,25874815 ! amino acid activation GO:0043038 92 52 0,000 0,24605809 0,25863511 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 76 53 0,000 0,25014565 0,26281678 ! RNA catabolic process GO:0006401 93 53 0,000 0,25014565 0,26270206 ! regulation of translational initiation GO:0006446 82 53 0,000 0,25014565 0,26258745 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,25014565 0,26247293 ! cell maturation GO:0048469 100 53 0,000 0,25014565 0,26235851 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,25421118 0,26650636 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,25421118 0,26639029 ! chloride transport GO:0006821 90 55 0,000 0,25825481 0,27050983 ! glucose catabolic process GO:0006007 82 55 0,000 0,25825481 0,27039211 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,25825481 0,2702745 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,25825481 0,27015699 ! aging GO:0007568 103 55 0,000 0,25825481 0,27003958 ! nuclear export GO:0051168 97 55 0,000 0,25825481 0,26992227 ! sensory perception of smell GO:0007608 80 56 0,000 0,26227665 0,27400678 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,26227665 0,27388785 ! regulation of DNA replication GO:0006275 101 56 0,000 0,26227665 0,27376903 ! proton transport GO:0015992 94 56 0,000 0,26227665 0,27365031 ! maintenance of location GO:0051235 118 57 0,000 0,26627681 0,27770351 ! hydrogen transport GO:0006818 97 58 0,000 0,27025542 0,28173073 ! regulation of endocytosis GO:0030100 91 58 0,000 0,27025542 0,28160872 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,27421258 0,28560843 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,27421258 0,28548484 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,27421258 0,28536136 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,27814842 0,28933207 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,27814842 0,28920704 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,27814842 0,28908211 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,28206304 0,29302404 ! mesoderm development GO:0007498 119 61 0,000 0,28206304 0,29289757 ! tRNA processing GO:0008033 89 61 0,000 0,28206304 0,29277121 ! viral reproductive process GO:0022415 126 62 0,000 0,28595656 0,29668456 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,28595656 0,29655668 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,2898291 0,30044326 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,2898291 0,30031387 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,29368076 0,30417387 ! cell redox homeostasis GO:0045454 102 64 0,000 0,29368076 0,30404299 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,29368076 0,30391222 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,29368076 0,30378156 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,29368076 0,30365101 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,29751166 0,30747983 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,29751166 0,30734781 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,30132191 0,31115043 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,30132191 0,31101695 ! secondary metabolic process GO:0019748 116 66 0,000 0,30132191 0,31088358 ! developmental maturation GO:0021700 116 66 0,000 0,30132191 0,31075033 ! chromosome segregation GO:0007059 113 67 0,000 0,30511162 0,3145238 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,30511162 0,3143891 ! hexose catabolic process GO:0019320 104 67 0,000 0,30511162 0,31425452 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,30511162 0,31412005 ! activation of immune response GO:0002253 105 67 0,000 0,30511162 0,31398569 ! amino acid transport GO:0006865 125 68 0,000 0,3088809 0,3177287 ! viral reproduction GO:0016032 134 68 0,000 0,3088809 0,31759292 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,3088809 0,31745725 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,31262985 0,32117311 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,31262985 0,32103603 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,31262985 0,32089907 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,31262985 0,32076223 ! antigen processing and presentation GO:0019882 104 69 0,000 0,31262985 0,3206255 ! amine catabolic process GO:0009310 117 71 0,000 0,32006724 0,32811324 ! humoral immune response GO:0006959 109 71 0,000 0,32006724 0,3279735 ! B cell activation GO:0042113 160 71 0,000 0,32006724 0,32783388 ! regulation of immune effector process GO:0002697 137 71 0,000 0,32006724 0,32769437 ! acute inflammatory response GO:0002526 113 72 0,000 0,32375588 0,33132993 ! learning or memory GO:0007611 147 73 0,000 0,32742464 0,33494204 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,32742464 0,3347997 ! fertilization GO:0009566 90 73 0,000 0,32742464 0,33465747 ! transition metal ion transport GO:0000041 126 74 0,000 0,33107362 0,33824336 ! neurotransmitter transport GO:0006836 123 74 0,000 0,33107362 0,3380998 ! meiosis GO:0007126 121 74 0,000 0,33107362 0,33795635 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,33107362 0,33781303 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,33107362 0,33766983 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,33470291 0,34122678 ! meiotic cell cycle GO:0051321 122 75 0,000 0,33470291 0,34108226 ! rhythmic process GO:0048511 128 75 0,000 0,33470291 0,34093785 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,33470291 0,34079357 ! defense response to bacterium GO:0042742 89 76 0,000 0,33831264 0,34432327 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,33831264 0,34417768 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,3419029 0,34768317 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,3419029 0,34753628 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,34902544 0,35462636 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,35255793 0,35806432 ! muscle cell differentiation GO:0042692 159 80 0,000 0,35255793 0,35791324 ! inorganic anion transport GO:0015698 138 80 0,000 0,35255793 0,35776229 ! T cell activation GO:0042110 168 81 0,000 0,35607137 0,36117526 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,35607137 0,36102305 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,35956585 0,36441257 ! response to drug GO:0042493 143 82 0,000 0,35956585 0,36425913 ! response to nutrient GO:0007584 125 82 0,000 0,35956585 0,36410582 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,35956585 0,36395265 ! regulation of lyase activity GO:0051339 160 83 0,000 0,36304149 0,36731616 ! response to unfolded protein GO:0006986 131 85 0,000 0,36993662 0,37413515 ! nucleosome assembly GO:0006334 122 85 0,000 0,36993662 0,37397795 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,36993662 0,37382088 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,37335632 0,3771181 ! chromatin assembly GO:0031497 124 86 0,000 0,37335632 0,37695984 ! alcohol catabolic process GO:0046164 130 86 0,000 0,37335632 0,37680172 ! amine transport GO:0015837 155 86 0,000 0,37335632 0,37664373 ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,37675757 0,37991564 ! cellular respiration GO:0045333 135 88 0,000 0,38014047 0,3831663 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,38014047 0,38300585 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,38685162 0,38960443 ! sterol metabolic process GO:0016125 152 91 0,000 0,39018006 0,39279215 ! response to protein stimulus GO:0051789 149 91 0,000 0,39018006 0,39262787 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,39018006 0,39246373 ! nucleosome organization GO:0034728 138 92 0,000 0,39349055 0,39562819 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,39349055 0,39546293 ! vitamin metabolic process GO:0006766 139 92 0,000 0,39349055 0,39529781 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,39678317 0,3984392 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,40331522 0,40482954 ! leukocyte differentiation GO:0002521 202 96 0,000 0,40655483 0,40791114 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,40655483 0,40774111 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,40655483 0,40757122 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,40977696 0,41063031 ! protein ubiquitination GO:0016567 217 97 0,000 0,40977696 0,41045935 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,4129817 0,41349728 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,4129817 0,41332528 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,41616915 0,41634219 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,41616915 0,41616915