Study Desmedt-ER-neg

Study informations

165 subnetworks in total page | file

2310 genes associated page | file

Enriched GO terms page

General informations

General Index page

Study Index page

Subnetwork 6231

score

DatasetScoreP-val 1P-val 2P-val 3Fisher Score
IPC0.75983.160e-034.990e-047.547e-011.190e-06
Loi0.22848.322e-021.215e-024.353e-014.402e-04
Schmidt0.67150.000e+000.000e+004.697e-020.000e+00
VanDeVijver0.79060.000e+000.000e+003.486e-030.000e+00
Wang0.25942.992e-034.661e-024.091e-015.705e-05

Expression data for subnetwork 6231 in each dataset

IPC | Loi | Schmidt | VanDeVijver | Wang |

Subnetwork structure for each dataset

Score for each gene in subnetwork 6231 in each dataset

Gene SymbolLinksFrequencyFrequency RankSubnetwork score rankGlobal rank IPCLoiSchmidtVanDeVijverWang
EP300EP300 on ITI EP300 on NCBI113414-0.1490.0870.1020.0520.025
PLXNB3PLXNB3 on ITI PLXNB3 on NCBI1119519221935-0.0430.152-0.1130.166-0.070
IFNAR2IFNAR2 on ITI IFNAR2 on NCBI444015581528-0.1000.0550.106-0.294-0.058
CUL7CUL7 on ITI CUL7 on NCBI355716211593-0.1570.176-0.108-0.0060.104
MAGED1MAGED1 on ITI MAGED1 on NCBI5360842828-0.1410.284-0.1520.2400.045
DLGAP4DLGAP4 on ITI DLGAP4 on NCBI7256727714-0.0290.180-0.2010.135-0.043
TAP1TAP1 on ITI TAP1 on NCBI2743192219020.210-0.116-0.118-0.078-0.146
EIF3EEIF3E on ITI EIF3E on NCBI11195192219350.003-0.1200.137-0.048-0.003
CDKN1ACDKN1A on ITI CDKN1A on NCBI1105150.0640.2540.030undef0.082
ABL1ABL1 on ITI ABL1 on NCBI13124727699-0.1520.2000.108undef-0.059
CALRCALR on ITI CALR on NCBI4440525520-0.1050.002-0.061-0.094-0.075
SMC3SMC3 on ITI SMC3 on NCBI53606146120.105-0.0960.2380.1370.047
C14orf1C14orf1 on ITI C14orf1 on NCBI1119519221935-0.1160.078-0.118-0.0110.041
SHC1SHC1 on ITI SHC1 on NCBI4440478479-0.090-0.041-0.0050.169-0.138
CDC42CDC42 on ITI CDC42 on NCBI26521791770.0470.242-0.0270.040-0.042
PTENPTEN on ITI PTEN on NCBI27501411350.0450.0550.0170.183-0.041
PTPN11PTPN11 on ITI PTPN11 on NCBI20818394-0.1520.0140.0660.3040.089
ERBB3ERBB3 on ITI ERBB3 on NCBI355719221888-0.171-0.007-0.141-0.019-0.098
POLE3POLE3 on ITI POLE3 on NCBI1795141138-0.083-0.0330.2310.0960.011
BTBD3BTBD3 on ITI BTBD3 on NCBI1119519221935-0.0050.1120.152-0.0350.056
KCTD3KCTD3 on ITI KCTD3 on NCBI35579139080.0510.0160.0860.2560.053
FRS2FRS2 on ITI FRS2 on NCBI2743108310840.2520.0930.174-0.092-0.095
CDK6CDK6 on ITI CDK6 on NCBI16104318314-0.2290.107-0.028-0.1180.104
STRAPSTRAP on ITI STRAP on NCBI72564124140.035-0.1280.0740.154-0.049
IL3IL3 on ITI IL3 on NCBI274318671849undef-0.0290.0000.153undef
VAV3VAV3 on ITI VAV3 on NCBI91966386220.0150.071-0.2450.1480.038
PIK3R1PIK3R1 on ITI PIK3R1 on NCBI127212-0.2370.3810.065undef-0.002
EGFREGFR on ITI EGFR on NCBI117313-0.1950.240-0.205-0.1870.065
MAGI3MAGI3 on ITI MAGI3 on NCBI274318421829-0.2330.199undefundefundef
MAP1BMAP1B on ITI MAP1B on NCBI691219-0.1230.263-0.1070.3040.100
INSRINSR on ITI INSR on NCBI9662362210.0630.1730.135-0.014-0.072
GADD45AGADD45A on ITI GADD45A on NCBI1114813511308-0.0570.076-0.0990.1090.093
JAK1JAK1 on ITI JAK1 on NCBI5360696680-0.1400.034-0.1760.1110.159
NUPR1NUPR1 on ITI NUPR1 on NCBI3557122212100.057-0.031-0.2410.1450.013
ARAR on ITI AR on NCBI4624141133-0.1630.081-0.0350.178-0.030
ACTBACTB on ITI ACTB on NCBI355712741258-0.0390.283-0.0610.1640.003
KLF5KLF5 on ITI KLF5 on NCBI769170.0770.117-0.007-0.110-0.006
RUNX1RUNX1 on ITI RUNX1 on NCBI5360906890-0.1610.1400.0160.1020.025
ITGB4ITGB4 on ITI ITGB4 on NCBI35341200.0210.313-0.1340.080-0.114
COPS6COPS6 on ITI COPS6 on NCBI161041310.147-0.0680.1280.2160.065
HSPB1HSPB1 on ITI HSPB1 on NCBI22691250.0530.1690.0170.1790.161
GAB1GAB1 on ITI GAB1 on NCBI536011021076-0.0690.084-0.1170.116-0.212

GO Enrichment output for subnetwork 6231 in each dataset

IPC file

NameAccession NumberLinkP-valCorrected P-val
phospholipid dephosphorylationGO:0046839GO:0046839 on GO9.34E-102.282E-06
cellular response to hormone stimulusGO:0032870GO:0032870 on GO1.174E-091.434E-06
regulation of cyclin-dependent protein kinase activityGO:0000079GO:0000079 on GO1.981E-091.613E-06
negative regulation of protein kinase B signaling cascadeGO:0051898GO:0051898 on GO2.794E-091.706E-06
regulation of protein export from nucleusGO:0046825GO:0046825 on GO6.5E-093.176E-06
organ growthGO:0035265GO:0035265 on GO6.5E-092.647E-06
negative regulation of peptide secretionGO:0002792GO:0002792 on GO6.5E-092.269E-06
negative regulation of focal adhesion formationGO:0051895GO:0051895 on GO6.5E-091.985E-06
regulation of focal adhesion formationGO:0051893GO:0051893 on GO1.296E-083.519E-06
regulation of growth hormone secretionGO:0060123GO:0060123 on GO1.296E-083.167E-06
regulation of cell-matrix adhesionGO:0001952GO:0001952 on GO2.168E-084.814E-06


Loi file

NameAccession NumberLinkP-valCorrected P-val
phospholipid dephosphorylationGO:0046839GO:0046839 on GO1.195E-092.874E-06
regulation of cyclin-dependent protein kinase activityGO:0000079GO:0000079 on GO2.995E-093.602E-06
negative regulation of protein kinase B signaling cascadeGO:0051898GO:0051898 on GO3.573E-092.866E-06
regulation of protein export from nucleusGO:0046825GO:0046825 on GO8.312E-094.999E-06
organ growthGO:0035265GO:0035265 on GO8.312E-094E-06
negative regulation of peptide secretionGO:0002792GO:0002792 on GO8.312E-093.333E-06
negative regulation of focal adhesion formationGO:0051895GO:0051895 on GO8.312E-092.857E-06
regulation of focal adhesion formationGO:0051893GO:0051893 on GO1.657E-084.984E-06
regulation of growth hormone secretionGO:0060123GO:0060123 on GO1.657E-084.43E-06
regulation of cell-matrix adhesionGO:0001952GO:0001952 on GO2.934E-087.058E-06
nerve growth factor receptor signaling pathwayGO:0048011GO:0048011 on GO2.974E-086.504E-06


Schmidt file

NameAccession NumberLinkP-valCorrected P-val
negative regulation of peptide secretionGO:0002792GO:0002792 on GO1.924E-094.426E-06
regulation of protein export from nucleusGO:0046825GO:0046825 on GO5.753E-096.616E-06
organ growthGO:0035265GO:0035265 on GO1.338E-081.026E-05
regulation of growth hormone secretionGO:0060123GO:0060123 on GO1.338E-087.692E-06
nerve growth factor receptor signaling pathwayGO:0048011GO:0048011 on GO2.666E-081.227E-05
cellular response to hormone stimulusGO:0032870GO:0032870 on GO4.141E-081.587E-05
regulation of cyclin-dependent protein kinase activityGO:0000079GO:0000079 on GO1.075E-073.534E-05
positive regulation of MAP kinase activityGO:0043406GO:0043406 on GO1.092E-073.138E-05
negative regulation of secretionGO:0051048GO:0051048 on GO2.569E-076.564E-05
activation of MAPK activityGO:0000187GO:0000187 on GO2.615E-076.014E-05
carbohydrate homeostasisGO:0033500GO:0033500 on GO3.563E-077.449E-05


VanDeVijver file

NameAccession NumberLinkP-valCorrected P-val
positive regulation of DNA replicationGO:0045740GO:0045740 on GO3.445E-076.349E-04
positive regulation of DNA metabolic processGO:0051054GO:0051054 on GO3.415E-063.147E-03
positive regulation of MAP kinase activityGO:0043406GO:0043406 on GO3.543E-062.176E-03
positive regulation of transferase activityGO:0051347GO:0051347 on GO3.72E-061.714E-03
positive regulation of cell cycleGO:0045787GO:0045787 on GO1.082E-053.989E-03
regulation of epithelial cell proliferationGO:0050678GO:0050678 on GO1.082E-053.324E-03
regulation of DNA replicationGO:0006275GO:0006275 on GO1.424E-053.748E-03
regulation of MAP kinase activityGO:0043405GO:0043405 on GO1.564E-053.602E-03
striated muscle tissue developmentGO:0014706GO:0014706 on GO1.684E-053.448E-03
positive regulation of nitric oxide biosynthetic processGO:0045429GO:0045429 on GO1.771E-053.264E-03
muscle tissue developmentGO:0060537GO:0060537 on GO2.088E-053.498E-03


Wang file

NameAccession NumberLinkP-valCorrected P-val
negative regulation of peptide secretionGO:0002792GO:0002792 on GO1.924E-094.426E-06
regulation of protein export from nucleusGO:0046825GO:0046825 on GO5.753E-096.616E-06
organ growthGO:0035265GO:0035265 on GO1.338E-081.026E-05
regulation of growth hormone secretionGO:0060123GO:0060123 on GO1.338E-087.692E-06
nerve growth factor receptor signaling pathwayGO:0048011GO:0048011 on GO2.666E-081.227E-05
cellular response to hormone stimulusGO:0032870GO:0032870 on GO4.141E-081.587E-05
regulation of cyclin-dependent protein kinase activityGO:0000079GO:0000079 on GO1.075E-073.534E-05
positive regulation of MAP kinase activityGO:0043406GO:0043406 on GO1.092E-073.138E-05
negative regulation of secretionGO:0051048GO:0051048 on GO2.569E-076.564E-05
activation of MAPK activityGO:0000187GO:0000187 on GO2.615E-076.014E-05
carbohydrate homeostasisGO:0033500GO:0033500 on GO3.563E-077.449E-05


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