pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6231-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! positive regulation of DNA replication GO:0045740 14 13 3,000 3,445E-07 6,349E-04 ! positive regulation of DNA metabolic process GO:0051054 23 22 3,000 3,415E-06 3,147E-03 ! positive regulation of MAP kinase activity GO:0043406 50 49 4,000 3,543E-06 2,176E-03 ! positive regulation of transferase activity GO:0051347 91 88 5,000 3,72E-06 1,714E-03 GO:0033674|positive regulation of kinase activity, ! positive regulation of cell cycle GO:0045787 29 29 3,000 1,082E-05 3,989E-03 ! regulation of epithelial cell proliferation GO:0050678 29 29 3,000 1,082E-05 3,324E-03 ! regulation of DNA replication GO:0006275 32 31 3,000 1,424E-05 3,748E-03 ! regulation of MAP kinase activity GO:0043405 67 66 4,000 1,564E-05 3,602E-03 ! striated muscle tissue development GO:0014706 69 67 4,000 1,684E-05 3,448E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 2,000 1,771E-05 3,264E-03 ! muscle tissue development GO:0060537 72 70 4,000 2,088E-05 3,498E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 3,000 2,336E-05 3,588E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 2,000 3,05E-05 4,323E-03 ! regulation of cell-substrate adhesion GO:0010810 14 13 2,000 3,05E-05 4,014E-03 GO:0001952|regulation of cell-matrix adhesion, ! activation of MAPK activity GO:0000187 39 39 3,000 3,619E-05 4,446E-03 ! negative regulation of epithelial cell proliferation GO:0050680 14 14 2,000 3,868E-05 4,456E-03 ! positive regulation of protein kinase activity GO:0045860 89 86 4,000 5,679E-05 6,156E-03 ! heart development GO:0007507 90 87 4,000 6,004E-05 6,147E-03 ! regulation of cell cycle process GO:0010564 50 48 3,000 8,296E-05 8,047E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 2,000 8,555E-05 7,883E-03 ! regulation of DNA metabolic process GO:0051052 51 50 3,000 9,75E-05 8,557E-03 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 2,000 1,012E-04 8,482E-03 ! regulation of protein stability GO:0031647 19 19 2,000 1,012E-04 8,113E-03 ! interphase of mitotic cell cycle GO:0051329 52 51 3,000 1,054E-04 8,096E-03 GO:0051325|interphase, ! posttranscriptional regulation of gene expression GO:0010608 98 98 4,000 1,061E-04 7,825E-03 ! muscle organ development GO:0007517 102 100 4,000 1,168E-04 8,283E-03 ! negative regulation of cell adhesion GO:0007162 21 20 2,000 1,187E-04 8,103E-03 ! peptidyl-tyrosine modification GO:0018212 21 20 2,000 1,187E-04 7,814E-03 ! regulation of cell adhesion GO:0030155 56 55 3,000 1,419E-04 9,018E-03 ! cell projection assembly GO:0030031 25 23 2,000 1,826E-04 0,01121516 ! peptidyl-amino acid modification GO:0018193 61 59 3,000 1,867E-04 0,01110119 ! gliogenesis GO:0042063 24 24 2,000 2,079E-04 0,01197571 ! glucose homeostasis GO:0042593 24 24 2,000 2,079E-04 0,01161281 GO:0033500|carbohydrate homeostasis, ! positive regulation of glucose metabolic process GO:0010907 5 5 1,000 2,349E-04 0,01273149 ! prostate gland development GO:0030850 5 5 1,000 2,349E-04 0,01236773 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 1,000 2,349E-04 0,01202419 GO:0010469|regulation of receptor activity, ! filopodium assembly GO:0046847 7 5 1,000 2,349E-04 0,01169921 GO:0030035|microspike assembly, ! tyrosine metabolic process GO:0006570 5 5 1,000 2,349E-04 0,01139133 ! sister chromatid cohesion GO:0007062 5 5 1,000 2,349E-04 0,01109925 ! regulation of phospholipase A2 activity GO:0032429 5 5 1,000 2,349E-04 0,01082177 ! corticosteroid receptor signaling pathway GO:0031958 5 5 1,000 2,349E-04 0,01055782 GO:0042921|glucocorticoid receptor signaling pathway, ! Schwann cell differentiation GO:0014037 5 5 1,000 2,349E-04 0,01030644 ! protein heterooligomerization GO:0051291 5 5 1,000 2,349E-04 0,01006676 ! positive regulation of phagocytosis GO:0050766 5 5 1,000 2,349E-04 9,838E-03 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 1,000 2,349E-04 9,619E-03 ! negative regulation of focal adhesion formation GO:0051895 6 5 1,000 2,349E-04 9,41E-03 ! peptidyl-lysine modification GO:0018205 5 5 1,000 2,349E-04 9,21E-03 ! sarcomere organization GO:0045214 5 5 1,000 2,349E-04 9,018E-03 ! nucleus localization GO:0051647 5 5 1,000 2,349E-04 8,834E-03 ! negative regulation of secretion GO:0051048 26 25 2,000 2,355E-04 8,68E-03 ! positive regulation of cellular component organization GO:0051130 65 65 3,000 2,72E-04 9,83E-03 ! cell growth GO:0016049 27 27 2,000 2,975E-04 0,01054294 ! protein amino acid autophosphorylation GO:0046777 28 28 2,000 3,32E-04 0,01154624 ! regulation of translation GO:0006417 69 69 3,000 3,425E-04 0,01168997 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 1,000 3,512E-04 0,01176898 ! N-terminal protein amino acid modification GO:0031365 6 6 1,000 3,512E-04 0,01155882 GO:0018409|peptide or protein amino-terminal blocking, ! virus-host interaction GO:0019048 6 6 1,000 3,512E-04 0,01135603 ! regulation of lipid kinase activity GO:0043550 6 6 1,000 3,512E-04 0,01116024 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 1,000 3,512E-04 0,01097108 ! regulation of phagocytosis GO:0050764 6 6 1,000 3,512E-04 0,01078823 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 1,000 3,512E-04 0,01061137 ! regulation of focal adhesion formation GO:0051893 7 6 1,000 3,512E-04 0,01044022 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 1,000 3,512E-04 0,0102745 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! regulation of embryonic development GO:0045995 6 6 1,000 3,512E-04 0,01011397 ! localization within membrane GO:0051668 6 6 1,000 3,512E-04 9,958E-03 ! growth GO:0040007 70 70 3,000 3,62E-04 0,01010885 ! regulation of cell migration GO:0030334 71 71 3,000 3,823E-04 0,01051572 ! negative regulation of signal transduction GO:0009968 71 71 3,000 3,823E-04 0,01036108 ! regulation of translational initiation GO:0006446 31 31 2,000 4,51E-04 0,01204631 ! regulation of myeloid cell differentiation GO:0045637 32 31 2,000 4,51E-04 0,01187422 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 1,000 4,902E-04 0,012724 ! positive regulation of cellular catabolic process GO:0031331 7 7 1,000 4,902E-04 0,01254727 ! positive regulation of survival gene product expression GO:0045885 7 7 1,000 4,902E-04 0,01237539 ! cardiac muscle tissue development GO:0048738 7 7 1,000 4,902E-04 0,01220816 ! myofibril assembly GO:0030239 7 7 1,000 4,902E-04 0,01204538 GO:0055002|striated muscle cell development, ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 1,000 4,902E-04 0,01188689 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! cranial nerve development GO:0021545 7 7 1,000 4,902E-04 0,01173252 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 1,000 4,902E-04 0,0115821 GO:0001953|negative regulation of cell-matrix adhesion, ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 2,000 4,96E-04 0,01157076 ! negative regulation of cell communication GO:0010648 76 76 3,000 4,961E-04 0,0114278 ! regulation of locomotion GO:0040012 79 79 3,000 5,749E-04 0,01308034 ! regulation of cell motion GO:0051270 79 79 3,000 5,749E-04 0,01292082 ! MAPKKK cascade GO:0000165 82 81 3,000 6,321E-04 0,01403675 ! positive regulation of phosphorylation GO:0042327 35 35 2,000 6,479E-04 0,01421479 ! sex determination GO:0007530 8 8 1,000 6,516E-04 0,01412715 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 1,000 6,516E-04 0,01396288 ! muscle cell development GO:0055001 8 8 1,000 6,516E-04 0,01380238 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 1,000 6,516E-04 0,01364554 ! blood vessel morphogenesis GO:0048514 84 83 3,000 6,934E-04 0,01435805 ! regulation of mitosis GO:0007088 37 36 2,000 7,044E-04 0,01442449 GO:0051783|regulation of nuclear division, ! positive regulation of cell migration GO:0030335 36 36 2,000 7,044E-04 0,01426598 ! positive regulation of phosphorus metabolic process GO:0010562 36 36 2,000 7,044E-04 0,01411091 GO:0045937|positive regulation of phosphate metabolic process, ! positive regulation of cell projection organization GO:0031346 9 9 1,000 8,351E-04 0,01654962 ! cortical actin cytoskeleton organization GO:0030866 10 9 1,000 8,351E-04 0,01637356 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 1,000 8,351E-04 0,01620121 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 1,000 8,351E-04 0,01603244 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 1,000 8,351E-04 0,01586716 ! pigmentation during development GO:0048066 9 9 1,000 8,351E-04 0,01570525 ! histone acetylation GO:0016573 9 9 1,000 8,351E-04 0,01554661 ! positive regulation of cell motion GO:0051272 39 39 2,000 8,925E-04 0,01644933 ! regulation of glucose metabolic process GO:0010906 10 10 1,000 1,041E-03 0,01898948 ! cortical cytoskeleton organization GO:0030865 11 10 1,000 1,041E-03 0,01880331 ! inositol metabolic process GO:0006020 10 10 1,000 1,041E-03 0,01862075 ! calcium-independent cell-cell adhesion GO:0016338 10 10 1,000 1,041E-03 0,01844171 ! centrosome cycle GO:0007098 10 10 1,000 1,041E-03 0,01826607 ! regulation of survival gene product expression GO:0045884 10 10 1,000 1,041E-03 0,01809375 ! protein export from nucleus GO:0006611 10 10 1,000 1,041E-03 0,01792465 ! regulation of erythrocyte differentiation GO:0045646 10 10 1,000 1,041E-03 0,01775868 ! negative regulation of neuron differentiation GO:0045665 10 10 1,000 1,041E-03 0,01759576 ! nerve development GO:0021675 10 10 1,000 1,041E-03 0,0174358 ! protein stabilization GO:0050821 10 10 1,000 1,041E-03 0,01727872 ! blood vessel development GO:0001568 95 94 3,000 1,107E-03 0,01822141 ! vasculature development GO:0001944 97 96 3,000 1,198E-03 0,01953706 ! myeloid leukocyte differentiation GO:0002573 12 11 1,000 1,268E-03 0,02049905 ! G1 phase of mitotic cell cycle GO:0000080 12 11 1,000 1,268E-03 0,0203208 ! positive regulation of hormone secretion GO:0046887 11 11 1,000 1,268E-03 0,02014562 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 1,000 1,268E-03 0,01997343 ! endothelial cell migration GO:0043542 11 11 1,000 1,268E-03 0,01980417 ! protein amino acid acetylation GO:0006473 11 11 1,000 1,268E-03 0,01963775 ! mitotic spindle organization GO:0007052 11 11 1,000 1,268E-03 0,0194741 ! interaction with host GO:0051701 11 11 1,000 1,268E-03 0,01931315 ! regulation of monooxygenase activity GO:0032768 11 11 1,000 1,268E-03 0,01915485 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 1,000 1,268E-03 0,01899912 GO:0006109|regulation of carbohydrate metabolic process, ! aromatic amino acid family metabolic process GO:0009072 11 11 1,000 1,268E-03 0,0188459 ! cellular response to hormone stimulus GO:0032870 48 46 2,000 1,448E-03 0,02134825 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 1,000 1,517E-03 0,02218726 ! positive regulation of angiogenesis GO:0045766 12 12 1,000 1,517E-03 0,02201255 ! actomyosin structure organization GO:0031032 12 12 1,000 1,517E-03 0,02184058 ! microtubule organizing center organization GO:0031023 12 12 1,000 1,517E-03 0,02167127 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 1,000 1,517E-03 0,02150457 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 1,000 1,517E-03 0,02134041 ! regulation of insulin secretion GO:0050796 12 12 1,000 1,517E-03 0,02117874 ! somitogenesis GO:0001756 13 12 1,000 1,517E-03 0,02101951 ! G1 phase GO:0051318 13 12 1,000 1,517E-03 0,02086264 ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 1,000 1,517E-03 0,02070811 ! negative regulation of translation GO:0017148 12 12 1,000 1,517E-03 0,02055584 ! cell cycle arrest GO:0007050 49 49 2,000 1,74E-03 0,02340314 ! skeletal muscle tissue development GO:0007519 50 49 2,000 1,74E-03 0,02323356 GO:0060538|skeletal muscle organ development, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 1,000 1,787E-03 0,02369543 ! negative regulation of hormone secretion GO:0046888 13 13 1,000 1,787E-03 0,02352618 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 1,000 1,787E-03 0,02335933 ! vasculogenesis GO:0001570 13 13 1,000 1,787E-03 0,02319483 ! negative regulation of protein kinase cascade GO:0010741 13 13 1,000 1,787E-03 0,02303262 ! regulation of peptide secretion GO:0002791 13 13 1,000 1,787E-03 0,02287268 ! protein tetramerization GO:0051262 13 13 1,000 1,787E-03 0,02271493 ! negative regulation of transport GO:0051051 51 50 2,000 1,845E-03 0,02328366 ! protein amino acid acylation GO:0043543 14 14 1,000 2,079E-03 0,02605937 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 1,000 2,079E-03 0,0258833 ! peptide transport GO:0015833 14 14 1,000 2,079E-03 0,02570958 ! protein amino acid dephosphorylation GO:0006470 55 54 2,000 2,303E-03 0,02829624 ! positive regulation of fibroblast proliferation GO:0048146 15 15 1,000 2,391E-03 0,02918151 ! negative regulation of protein complex assembly GO:0031333 15 15 1,000 2,391E-03 0,02898952 ! striated muscle cell differentiation GO:0051146 16 15 1,000 2,391E-03 0,02880005 ! insulin receptor signaling pathway GO:0008286 17 15 1,000 2,391E-03 0,02861304 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 1,000 2,391E-03 0,02842844 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 1,000 2,391E-03 0,0282462 ! microtubule cytoskeleton organization GO:0000226 55 55 2,000 2,428E-03 0,02849821 ! reproductive developmental process GO:0003006 56 56 2,000 2,556E-03 0,0298202 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 1,000 2,724E-03 0,03157442 ! positive regulation of mitosis GO:0045840 16 16 1,000 2,724E-03 0,03137708 GO:0051785|positive regulation of nuclear division, ! segmentation GO:0035282 17 16 1,000 2,724E-03 0,03118219 ! triglyceride metabolic process GO:0006641 16 16 1,000 2,724E-03 0,0309897 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 1,000 2,724E-03 0,03079958 ! polyol metabolic process GO:0019751 16 16 1,000 2,724E-03 0,03061178 ! positive regulation of catabolic process GO:0009896 16 16 1,000 2,724E-03 0,03042626 ! dephosphorylation GO:0016311 60 59 2,000 2,968E-03 0,03295229 ! regulation of fibroblast proliferation GO:0048145 17 17 1,000 3,078E-03 0,03396486 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 3,078E-03 0,03376269 ! regulation of oxidoreductase activity GO:0051341 17 17 1,000 3,078E-03 0,03356291 ! regulation of osteoblast differentiation GO:0045667 17 17 1,000 3,078E-03 0,03336548 ! pigmentation GO:0043473 17 17 1,000 3,078E-03 0,03317036 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 2,000 3,264E-03 0,03497209 ! regulation of cellular component biogenesis GO:0044087 63 62 2,000 3,418E-03 0,03641522 ! regulation of cell projection organization GO:0031344 19 18 1,000 3,452E-03 0,03656 ! regulation of cellular catabolic process GO:0031329 18 18 1,000 3,452E-03 0,03635109 ! response to calcium ion GO:0051592 18 18 1,000 3,452E-03 0,03614455 ! neutral lipid metabolic process GO:0006638 18 18 1,000 3,452E-03 0,03594034 GO:0006639|acylglycerol metabolic process, ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 1,000 3,452E-03 0,03573843 ! regulation of secretion GO:0051046 65 63 2,000 3,577E-03 0,03683026 ! negative regulation of cellular component organization GO:0051129 65 63 2,000 3,577E-03 0,03662565 ! glycerolipid metabolic process GO:0046486 65 64 2,000 3,74E-03 0,03808632 ! angiogenesis GO:0001525 65 64 2,000 3,74E-03 0,03787706 ! DNA damage checkpoint GO:0000077 19 19 1,000 3,846E-03 0,03873165 ! glial cell differentiation GO:0010001 19 19 1,000 3,846E-03 0,03852115 ! regulation of JAK-STAT cascade GO:0046425 19 19 1,000 3,846E-03 0,03831293 ! peripheral nervous system development GO:0007422 19 19 1,000 3,846E-03 0,03810695 ! response to heat GO:0009408 19 19 1,000 3,846E-03 0,03790317 ! negative regulation of cell differentiation GO:0045596 68 67 2,000 4,258E-03 0,04173782 ! Ras protein signal transduction GO:0007265 69 67 2,000 4,258E-03 0,04151699 ! establishment or maintenance of cell polarity GO:0007163 21 20 1,000 4,26E-03 0,04132172 ! organic ether metabolic process GO:0018904 20 20 1,000 4,26E-03 0,04110537 GO:0006662|glycerol ether metabolic process, ! negative regulation of neuron apoptosis GO:0043524 21 20 1,000 4,26E-03 0,04089128 ! regulation of cell size GO:0008361 68 68 2,000 4,439E-03 0,04239028 ! sensory perception of sound GO:0007605 71 69 2,000 4,625E-03 0,04394077 GO:0050954|sensory perception of mechanical stimulus, ! regulation of mitotic cell cycle GO:0007346 72 69 2,000 4,625E-03 0,04371543 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 1,000 4,694E-03 0,04413665 ! DNA integrity checkpoint GO:0031570 21 21 1,000 4,694E-03 0,04391261 ! regulation of multicellular organism growth GO:0040014 21 21 1,000 4,694E-03 0,04369082 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 1,000 4,694E-03 0,04347127 ! cellular response to insulin stimulus GO:0032869 23 21 1,000 4,694E-03 0,04325392 ! positive regulation of transport GO:0051050 71 70 2,000 4,816E-03 0,04416085 ! positive regulation of transcription factor activity GO:0051091 22 22 1,000 5,147E-03 0,0469629 GO:0090047|positive regulation of transcription regulator activity, ! hormone-mediated signaling GO:0009755 22 22 1,000 5,147E-03 0,04673156 ! spindle organization GO:0007051 22 22 1,000 5,147E-03 0,04650248 ! pigment biosynthetic process GO:0046148 22 22 1,000 5,147E-03 0,04627564 ! regulation of hormone secretion GO:0046883 23 23 1,000 5,62E-03 0,05028126 ! positive regulation of growth GO:0045927 23 23 1,000 5,62E-03 0,05003835 ! calcium-mediated signaling GO:0019722 23 23 1,000 5,62E-03 0,04979778 ! regulation of protein modification process GO:0031399 79 78 2,000 6,516E-03 0,0574597 ! positive regulation of protein kinase cascade GO:0010740 79 78 2,000 6,516E-03 0,05718608 ! regulation of gene-specific transcription GO:0032583 25 25 1,000 6,623E-03 0,05785087 ! regulation of intracellular protein transport GO:0033157 25 25 1,000 6,623E-03 0,05757799 ! positive regulation of DNA binding GO:0043388 26 25 1,000 6,623E-03 0,05730767 ! heart morphogenesis GO:0003007 25 25 1,000 6,623E-03 0,05703988 ! regulation of endocytosis GO:0030100 25 25 1,000 6,623E-03 0,05677457 ! JAK-STAT cascade GO:0007259 26 25 1,000 6,623E-03 0,05651173 ! neuron projection development GO:0031175 85 80 2,000 6,99E-03 0,05936738 ! positive regulation of binding GO:0051099 27 26 1,000 7,153E-03 0,06047246 ! negative regulation of cell migration GO:0030336 26 26 1,000 7,153E-03 0,06019633 ! pigment metabolic process GO:0042440 26 26 1,000 7,153E-03 0,05992271 ! response to insulin stimulus GO:0032868 28 26 1,000 7,153E-03 0,05965157 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 1,000 7,701E-03 0,06393594 ! histone modification GO:0016570 28 28 1,000 8,268E-03 0,06833423 ! viral reproductive process GO:0022415 29 29 1,000 8,853E-03 0,07284341 ! phosphoinositide metabolic process GO:0030384 29 29 1,000 8,853E-03 0,07251967 ! antigen processing and presentation GO:0019882 29 29 1,000 8,853E-03 0,07219878 ! covalent chromatin modification GO:0016569 29 29 1,000 8,853E-03 0,07188073 ! response to UV GO:0009411 29 29 1,000 8,853E-03 0,07156546 ! activation of phospholipase C activity GO:0007202 30 30 1,000 9,457E-03 0,07610748 GO:0010863|positive regulation of phospholipase C activity, ! response to temperature stimulus GO:0009266 30 30 1,000 9,457E-03 0,07577658 ! regulation of ossification GO:0030278 30 30 1,000 9,457E-03 0,07544854 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 1,000 9,457E-03 0,07512333 ! establishment of organelle localization GO:0051656 31 30 1,000 9,457E-03 0,07480091 ! negative regulation of cell cycle GO:0045786 92 91 2,000 9,962E-03 0,07845791 ! positive regulation of phospholipase activity GO:0010518 31 31 1,000 0,01007773 0,07903516 ! aging GO:0007568 32 31 1,000 0,01007773 0,07870026 ! regulation of intracellular transport GO:0032386 31 31 1,000 0,01007773 0,07836819 ! negative regulation of cell motion GO:0051271 31 31 1,000 0,01007773 0,07803892 ! lipid modification GO:0030258 32 32 1,000 0,01071652 0,08263824 ! regulation of phospholipase activity GO:0010517 32 32 1,000 0,01071652 0,08229392 ! regulation of vesicle-mediated transport GO:0060627 33 32 1,000 0,01071652 0,08195245 ! nuclear export GO:0051168 32 32 1,000 0,01071652 0,0816138 ! positive regulation of lipase activity GO:0060193 32 32 1,000 0,01071652 0,08127794 ! maintenance of location GO:0051235 33 32 1,000 0,01071652 0,08094484 ! regulation of protein complex assembly GO:0043254 33 33 1,000 0,01137282 0,0855515 ! regulation of neuron differentiation GO:0045664 34 33 1,000 0,01137282 0,08520373 ! regulation of neuron apoptosis GO:0043523 34 33 1,000 0,01137282 0,08485877 ! regulation of angiogenesis GO:0045765 35 34 1,000 0,01204648 0,08952283 ! regulation of bone remodeling GO:0046850 34 34 1,000 0,01204648 0,0891633 ! response to metal ion GO:0010038 34 34 1,000 0,01204648 0,08880665 ! muscle cell differentiation GO:0042692 35 34 1,000 0,01204648 0,08845284 ! regulation of lipid metabolic process GO:0019216 34 34 1,000 0,01204648 0,08810183 ! secondary metabolic process GO:0019748 34 34 1,000 0,01204648 0,0877536 ! response to peptide hormone stimulus GO:0043434 36 34 1,000 0,01204648 0,08740812 ! viral reproduction GO:0016032 34 34 1,000 0,01204648 0,08706534 ! anti-apoptosis GO:0006916 100 99 2,000 0,01252139 0,09014422 ! multicellular organism reproduction GO:0032504 36 35 1,000 0,0127373 0,09134183 GO:0048609|reproductive process in a multicellular organism, ! regulation of tissue remodeling GO:0034103 35 35 1,000 0,0127373 0,09098779 ! response to hormone stimulus GO:0009725 102 100 2,000 0,01286552 0,09154888 ! hemopoiesis GO:0030097 104 100 2,000 0,01286552 0,09119677 ! response to inorganic substance GO:0010035 36 36 1,000 0,01344512 0,09494008 ! positive regulation of organelle organization GO:0010638 36 36 1,000 0,01344512 0,09457771 ! integrin-mediated signaling pathway GO:0007229 36 36 1,000 0,01344512 0,0942181 ! regulation of lipase activity GO:0060191 36 36 1,000 0,01344512 0,09386121 ! regulation of transcription factor activity GO:0051090 38 37 1,000 0,01416976 0,09854667 GO:0090046|regulation of transcription regulator activity, ! meiosis GO:0007126 37 37 1,000 0,01416976 0,09817619 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of protein kinase activity GO:0006469 37 37 1,000 0,01416976 0,09780849 ! lung development GO:0030324 38 37 1,000 0,01416976 0,09744353 ! DNA damage response, signal transduction GO:0042770 37 37 1,000 0,01416976 0,09708129 ! regulation of Rho protein signal transduction GO:0035023 37 37 1,000 0,01416976 0,09672173 ! positive regulation of secretion GO:0051047 39 38 1,000 0,01491104 0,1014061 ! negative regulation of kinase activity GO:0033673 38 38 1,000 0,01491104 0,10103328 ! cell-matrix adhesion GO:0007160 39 38 1,000 0,01491104 0,10066319 ! chromosome segregation GO:0007059 38 38 1,000 0,01491104 0,10029581 ! urogenital system development GO:0001655 38 38 1,000 0,01491104 0,0999311 ! meiotic cell cycle GO:0051321 38 38 1,000 0,01491104 0,09956903 ! steroid hormone receptor signaling pathway GO:0030518 38 38 1,000 0,01491104 0,09920957 ! regulation of homeostatic process GO:0032844 38 38 1,000 0,01491104 0,0988527 ! positive regulation of protein modification process GO:0031401 39 39 1,000 0,0156688 0,10350394 ! respiratory tube development GO:0030323 40 39 1,000 0,0156688 0,10313428 ! response to unfolded protein GO:0006986 39 39 1,000 0,0156688 0,10276726 ! cytokine-mediated signaling pathway GO:0019221 39 39 1,000 0,0156688 0,10240283 ! respiratory system development GO:0060541 40 39 1,000 0,0156688 0,10204098 ! protein oligomerization GO:0051259 39 39 1,000 0,0156688 0,10168169 ! negative regulation of transferase activity GO:0051348 40 40 1,000 0,01644286 0,1063305 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 1,000 0,01644286 0,10595871 ! myeloid cell differentiation GO:0030099 42 40 1,000 0,01644286 0,10558952 ! organelle localization GO:0051640 41 40 1,000 0,01644286 0,10522289 ! cell cycle checkpoint GO:0000075 42 41 1,000 0,01723305 0,10989799 ! cell-substrate adhesion GO:0031589 43 42 1,000 0,01803921 0,11464232 ! response to protein stimulus GO:0051789 42 42 1,000 0,01803921 0,11424836 ! reproductive structure development GO:0048608 43 43 1,000 0,01886117 0,11904499 ! regulation of DNA binding GO:0051101 47 45 1,000 0,02055182 0,12927302 ! sex differentiation GO:0007548 47 47 1,000 0,02230367 0,1398152 ! regulation of catabolic process GO:0009894 48 47 1,000 0,02230367 0,13934125 ! glycerophospholipid metabolic process GO:0006650 49 48 1,000 0,02320215 0,14446474 ! leukocyte differentiation GO:0002521 50 49 1,000 0,02411545 0,14964569 ! ossification GO:0001503 50 49 1,000 0,02411545 0,14914352 GO:0060348|bone development, ! gland development GO:0048732 51 49 1,000 0,02411545 0,14864471 ! rRNA transcription GO:0009303 5 5 0,000 0,02447333 0,15034783 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,02447333 0,14984834 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,02447333 0,14935215 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,02447333 0,14885924 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,02447333 0,14836957 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,02447333 0,14788311 ! reproductive cellular process GO:0048610 5 5 0,000 0,02447333 0,14739984 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,02447333 0,14691971 ! metencephalon development GO:0022037 5 5 0,000 0,02447333 0,14644269 ! water transport GO:0006833 5 5 0,000 0,02447333 0,14596877 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,02447333 0,1454979 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,02447333 0,14503006 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,02447333 0,14456522 ! glycerol metabolic process GO:0006071 5 5 0,000 0,02447333 0,14410335 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,02447333 0,14364443 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,02447333 0,14318841 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,02447333 0,14273528 ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,02447333 0,14228502 ! CTP metabolic process GO:0046036 5 5 0,000 0,02447333 0,14183758 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,02447333 0,14139295 ! GTP metabolic process GO:0046039 5 5 0,000 0,02447333 0,14095109 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,02447333 0,14051199 ! mRNA stabilization GO:0048255 5 5 0,000 0,02447333 0,14007562 GO:0043489|RNA stabilization, ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,02447333 0,13964195 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,02447333 0,13921096 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,02447333 0,13878261 ! social behavior GO:0035176 5 5 0,000 0,02447333 0,1383569 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,02447333 0,13793379 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,02447333 0,13751326 ! memory GO:0007613 5 5 0,000 0,02447333 0,13709529 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 0,02447333 0,13667985 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,02447333 0,13626692 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,02447333 0,13585648 ! response to lipid GO:0033993 5 5 0,000 0,02447333 0,1354485 ! erythrocyte maturation GO:0043249 5 5 0,000 0,02447333 0,13504296 ! hippocampus development GO:0021766 6 5 0,000 0,02447333 0,13463985 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,02447333 0,13423914 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,02447333 0,1338408 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,02447333 0,13344482 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,02447333 0,13305118 ! mechanosensory behavior GO:0007638 5 5 0,000 0,02447333 0,13265985 ! heart looping GO:0001947 5 5 0,000 0,02447333 0,13227082 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,02447333 0,13188406 ! response to interferon-gamma GO:0034341 5 5 0,000 0,02447333 0,13149956 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,02447333 0,1311173 ! endocrine pancreas development GO:0031018 5 5 0,000 0,02447333 0,13073725 ! pH reduction GO:0045851 5 5 0,000 0,02447333 0,13035939 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,02447333 0,12998372 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,02447333 0,1296102 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,02447333 0,12923882 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,02447333 0,12886957 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,02447333 0,12850242 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,02447333 0,12813736 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 0,02447333 0,12777436 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,02447333 0,12741342 ! adrenal gland development GO:0030325 5 5 0,000 0,02447333 0,12705451 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,02447333 0,12669761 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,02447333 0,12634272 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,02447333 0,1259898 ! astrocyte differentiation GO:0048708 5 5 0,000 0,02447333 0,12563886 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,02447333 0,12528986 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,02447333 0,1249428 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,02447333 0,12459765 GO:0033135|regulation of peptidyl-serine phosphorylation, ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,02447333 0,12425441 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,02447333 0,12391305 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,02447333 0,12357356 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,02447333 0,12323593 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,02447333 0,12290014 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,02447333 0,12256617 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,02447333 0,12223401 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,02447333 0,12190365 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,02447333 0,12157507 GO:0021952|central nervous system projection neuron axonogenesis, ! response to ATP GO:0033198 5 5 0,000 0,02447333 0,12124825 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,02447333 0,12092319 ! regulation of appetite GO:0032098 5 5 0,000 0,02447333 0,12059987 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,02447333 0,12027827 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,02447333 0,11995838 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,02447333 0,11964019 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,02447333 0,11932368 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,02447333 0,11900884 ! receptor clustering GO:0043113 5 5 0,000 0,02447333 0,11869566 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,02447333 0,11838412 ! fear response GO:0042596 5 5 0,000 0,02447333 0,11807421 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 0,02447333 0,11776593 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,02447333 0,11745924 ! retinol metabolic process GO:0042572 5 5 0,000 0,02447333 0,11715416 ! temperature homeostasis GO:0001659 5 5 0,000 0,02447333 0,11685065 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,02447333 0,11654871 ! parturition GO:0007567 5 5 0,000 0,02447333 0,11624832 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02447333 0,11594949 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,02447333 0,11565218 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,02447333 0,11535639 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,02447333 0,11506212 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,02447333 0,11476934 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,02447333 0,11447805 ! response to UV-B GO:0010224 5 5 0,000 0,02447333 0,11418823 ! oligodendrocyte development GO:0014003 5 5 0,000 0,02447333 0,11389987 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,02447333 0,11361297 ! activated T cell proliferation GO:0050798 5 5 0,000 0,02447333 0,11332751 ! interaction with symbiont GO:0051702 5 5 0,000 0,02447333 0,11304348 ! cellular extravasation GO:0045123 5 5 0,000 0,02447333 0,11276087 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,02447333 0,11247968 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,02447333 0,11219988 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,02447333 0,11192146 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,02447333 0,11164443 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,02447333 0,11136877 ! response to amine stimulus GO:0014075 5 5 0,000 0,02447333 0,11109446 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,02447333 0,1108215 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,02447333 0,11054988 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,02447333 0,11027958 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,02447333 0,11001061 ! neuron recognition GO:0008038 5 5 0,000 0,02447333 0,10974294 ! decidualization GO:0046697 5 5 0,000 0,02447333 0,10947658 ! hair follicle maturation GO:0048820 5 5 0,000 0,02447333 0,1092115 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,02447333 0,1089477 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,02447333 0,10868518 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,02447333 0,10842392 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,02447333 0,10816391 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,02447333 0,10790514 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,02447333 0,10764761 ! postreplication repair GO:0006301 5 5 0,000 0,02447333 0,10739131 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,02447333 0,10713622 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 0,02447333 0,10688235 ! histone methylation GO:0016571 5 5 0,000 0,02447333 0,10662967 ! DNA methylation GO:0006306 5 5 0,000 0,02447333 0,10637818 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,02447333 0,10612788 ! T cell lineage commitment GO:0002360 5 5 0,000 0,02447333 0,10587876 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,02447333 0,1056308 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,02447333 0,105384 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,02447333 0,10513834 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,02447333 0,10489384 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,02447333 0,10465046 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,02447333 0,10440822 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,02447333 0,10416709 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,02447333 0,10392707 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,02447333 0,10368816 ! sterol catabolic process GO:0016127 5 5 0,000 0,02447333 0,10345034 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,02447333 0,10321362 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,02447333 0,10297797 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,02447333 0,10274339 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,02447333 0,10250989 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,02447333 0,10227744 ! zymogen activation GO:0031638 5 5 0,000 0,02447333 0,10204604 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,02447333 0,10181569 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,02447333 0,10158637 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,02447333 0,10135809 ! negative regulation of neuroblast proliferation GO:0007406 5 5 0,000 0,02447333 0,10113083 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,02447333 0,10090459 ! nucleosome positioning GO:0016584 5 5 0,000 0,02447333 0,10067935 ! regulation of isotype switching GO:0045191 5 5 0,000 0,02447333 0,10045512 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,02447333 0,10023189 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,02447333 0,10000964 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,02447333 0,09978838 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,02447333 0,0995681 ! NADPH regeneration GO:0006740 5 5 0,000 0,02447333 0,09934879 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,02447333 0,09913044 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,02447333 0,09891305 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,02447333 0,09869661 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,02447333 0,09848111 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,02447333 0,09826656 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,02447333 0,09805293 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,02447333 0,09784024 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,02447333 0,09762846 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,02447333 0,0974176 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 0,02447333 0,09720765 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,02447333 0,0969986 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,02447333 0,09679045 ! spleen development GO:0048536 5 5 0,000 0,02447333 0,09658319 ! male genitalia development GO:0030539 5 5 0,000 0,02447333 0,09637682 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,02447333 0,09617132 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,02447333 0,0959667 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,02447333 0,09576295 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,02447333 0,09556006 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,02447333 0,09535803 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,02447333 0,09515686 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,02447333 0,09495653 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,02447333 0,09475704 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,02447333 0,09455839 ! ATP catabolic process GO:0006200 5 5 0,000 0,02447333 0,09436056 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,02447333 0,09416357 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,02447333 0,0939674 ! blastocyst formation GO:0001825 5 5 0,000 0,02447333 0,09377204 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,02447333 0,09357749 ! embryonic gut development GO:0048566 5 5 0,000 0,02447333 0,09338375 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,02447333 0,09319081 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,02447333 0,09299866 ! activation of innate immune response GO:0002218 5 5 0,000 0,02447333 0,0928073 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 0,02447333 0,09261673 ! catecholamine transport GO:0051937 5 5 0,000 0,02447333 0,09242695 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,02447333 0,09223793 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,02447333 0,09204969 ! muscle adaptation GO:0043500 5 5 0,000 0,02447333 0,09186222 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,02447333 0,09167551 ! embryonic heart tube development GO:0035050 5 5 0,000 0,02447333 0,09148955 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,02447333 0,09130435 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,02447333 0,0911199 ! defense response to fungus GO:0050832 5 5 0,000 0,02447333 0,09093619 ! lysogeny GO:0030069 5 5 0,000 0,02447333 0,09075322 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,02447333 0,09057098 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,02447333 0,09038948 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,02447333 0,0902087 ! response to nicotine GO:0035094 5 5 0,000 0,02447333 0,09002864 ! establishment of cell polarity GO:0030010 5 5 0,000 0,02447333 0,0898493 ! mitochondrion localization GO:0051646 5 5 0,000 0,02447333 0,08967068 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,02447333 0,08949276 ! regulation of neurogenesis GO:0050767 51 50 1,000 0,0250434 0,09139602 ! anterior/posterior pattern formation GO:0009952 51 50 1,000 0,0250434 0,0912154 ! protein maturation GO:0051604 51 51 1,000 0,02598586 0,09446142 ! regulation of GTPase activity GO:0043087 53 52 1,000 0,02694266 0,09774671 ! response to light stimulus GO:0009416 53 52 1,000 0,02694266 0,09755467 ! response to hypoxia GO:0001666 53 53 1,000 0,02791365 0,10087228 ! regulation of protein transport GO:0051223 53 53 1,000 0,02791365 0,10067488 GO:0070201|regulation of establishment of protein localization, ! response to oxygen levels GO:0070482 55 54 1,000 0,02889868 0,10402396 ! response to virus GO:0009615 54 54 1,000 0,02889868 0,10382118 ! hormone metabolic process GO:0042445 55 54 1,000 0,02889868 0,10361919 ! axon extension GO:0048675 7 6 0,000 0,02929775 0,10484614 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,02929775 0,10464295 ! tRNA modification GO:0006400 6 6 0,000 0,02929775 0,10444054 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,02929775 0,10423892 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,02929775 0,10403808 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,02929775 0,103838 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,02929775 0,1036387 ! regulation of S phase GO:0033261 6 6 0,000 0,02929775 0,10344016 ! myotube differentiation GO:0014902 6 6 0,000 0,02929775 0,10324237 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,02929775 0,10304535 ! bone remodeling GO:0046849 6 6 0,000 0,02929775 0,10284907 ! N-glycan processing GO:0006491 6 6 0,000 0,02929775 0,10265354 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,02929775 0,10245875 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,02929775 0,1022647 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,02929775 0,10207138 ! RNA methylation GO:0001510 6 6 0,000 0,02929775 0,10187879 ! cartilage condensation GO:0001502 7 6 0,000 0,02929775 0,10168693 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,02929775 0,10149579 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 0,02929775 0,10130537 GO:0050927|positive regulation of positive chemotaxis, ! succinate metabolic process GO:0006105 7 6 0,000 0,02929775 0,10111566 ! artery development GO:0060840 6 6 0,000 0,02929775 0,10092666 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,02929775 0,10073836 ! bile acid metabolic process GO:0008206 6 6 0,000 0,02929775 0,10055077 ! androgen metabolic process GO:0008209 6 6 0,000 0,02929775 0,10036387 ! estrogen metabolic process GO:0008210 6 6 0,000 0,02929775 0,10017766 ! limbic system development GO:0021761 7 6 0,000 0,02929775 0,09999215 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,02929775 0,09980732 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 0,000 0,02929775 0,09962318 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,02929775 0,09943971 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,02929775 0,09925691 ! pathogenesis GO:0009405 6 6 0,000 0,02929775 0,09907479 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,02929775 0,09889334 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,02929775 0,09871254 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,02929775 0,09853241 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,02929775 0,09835293 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,02929775 0,09817411 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,02929775 0,09799594 ! arginine metabolic process GO:0006525 6 6 0,000 0,02929775 0,09781841 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,02929775 0,09764152 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,02929775 0,09746527 ! glutamate catabolic process GO:0006538 7 6 0,000 0,02929775 0,09728966 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,02929775 0,09711468 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,02929775 0,09694033 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,02929775 0,0967666 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,02929775 0,09659349 ! ER overload response GO:0006983 6 6 0,000 0,02929775 0,096421 ! V(D)J recombination GO:0033151 6 6 0,000 0,02929775 0,09624913 ! focal adhesion formation GO:0048041 7 6 0,000 0,02929775 0,09607787 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,02929775 0,09590721 ! negative regulation of T cell proliferation GO:0042130 6 6 0,000 0,02929775 0,09573717 GO:0070667|negative regulation of mast cell proliferation, ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,02929775 0,09556772 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,02929775 0,09539887 ! regulation of heart rate GO:0002027 6 6 0,000 0,02929775 0,09523062 ! lipid digestion GO:0044241 6 6 0,000 0,02929775 0,09506296 ! asymmetric protein localization GO:0008105 6 6 0,000 0,02929775 0,09489589 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,02929775 0,09472941 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,02929775 0,0945635 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,02929775 0,09439818 ! regulation of vascular permeability GO:0043114 6 6 0,000 0,02929775 0,09423344 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,02929775 0,09406927 ! ruffle organization GO:0031529 6 6 0,000 0,02929775 0,09390567 ! peptidyl-serine phosphorylation GO:0018105 6 6 0,000 0,02929775 0,09374264 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,02929775 0,09358018 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,02929775 0,09341827 ! neutral amino acid transport GO:0015804 6 6 0,000 0,02929775 0,09325693 ! L-amino acid transport GO:0015807 6 6 0,000 0,02929775 0,09309614 ! bone mineralization GO:0030282 6 6 0,000 0,02929775 0,09293591 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,02929775 0,09277622 ! negative regulation of ossification GO:0030279 6 6 0,000 0,02929775 0,09261709 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,02929775 0,09245849 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of bone resorption GO:0045124 6 6 0,000 0,02929775 0,09230045 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,02929775 0,09214294 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,02929775 0,09198596 ! G1 DNA damage checkpoint GO:0031571 6 6 0,000 0,02929775 0,09182953 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,02929775 0,09167362 ! regulation of organ growth GO:0046620 6 6 0,000 0,02929775 0,09151824 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,02929775 0,09136339 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,02929775 0,09120906 ! response to dsRNA GO:0043331 6 6 0,000 0,02929775 0,09105525 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,02929775 0,09090195 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,02929775 0,09074918 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! regulation of T cell differentiation in the thymus GO:0033081 6 6 0,000 0,02929775 0,09059691 ! genitalia development GO:0048806 6 6 0,000 0,02929775 0,09044516 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,02929775 0,09029391 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 0,000 0,02929775 0,09014317 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,02929775 0,08999294 ! multicellular organismal aging GO:0010259 6 6 0,000 0,02929775 0,0898432 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,02929775 0,08969396 ! erythrocyte development GO:0048821 6 6 0,000 0,02929775 0,08954521 ! renal water homeostasis GO:0003091 6 6 0,000 0,02929775 0,08939696 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,02929775 0,08924919 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,02929775 0,08910192 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,02929775 0,08895513 ! ribosome assembly GO:0042255 6 6 0,000 0,02929775 0,08880882 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,02929775 0,08866299 ! diencephalon development GO:0021536 6 6 0,000 0,02929775 0,08851764 ! fucose catabolic process GO:0019317 6 6 0,000 0,02929775 0,08837277 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,02929775 0,08822837 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 0,02929775 0,08808444 ! regulation of lipid transport GO:0032368 6 6 0,000 0,02929775 0,08794098 ! regulation of cell division GO:0051302 6 6 0,000 0,02929775 0,08779799 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,02929775 0,08765546 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,02929775 0,08751339 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,02929775 0,08737178 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,02929775 0,08723063 ! neuroblast proliferation GO:0007405 6 6 0,000 0,02929775 0,08708994 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,02929775 0,0869497 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,02929775 0,08680991 ! regulation of glucose transport GO:0010827 6 6 0,000 0,02929775 0,08667056 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,02929775 0,08653167 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,02929775 0,08639322 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,02929775 0,08625521 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,02929775 0,08611764 ! thymus development GO:0048538 6 6 0,000 0,02929775 0,08598051 ! lymph node development GO:0048535 6 6 0,000 0,02929775 0,08584382 ! organic cation transport GO:0015695 6 6 0,000 0,02929775 0,08570756 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,02929775 0,08557173 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,02929775 0,08543633 ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,02929775 0,08530136 ! sperm-egg recognition GO:0035036 7 6 0,000 0,02929775 0,08516682 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,02929775 0,08503269 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,02929775 0,084899 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,02929775 0,08476572 ! alditol metabolic process GO:0019400 6 6 0,000 0,02929775 0,08463285 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,02929775 0,08450041 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,02929775 0,08436838 ! maternal placenta development GO:0001893 6 6 0,000 0,02929775 0,08423676 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,02929775 0,08410555 ! regulation of nervous system development GO:0051960 57 56 1,000 0,03091022 0,08859647 ! regulation of binding GO:0051098 60 57 1,000 0,03193643 0,09139571 ! regulation of protein localization GO:0032880 58 57 1,000 0,03193643 0,09125401 ! regulation of cell development GO:0060284 60 59 1,000 0,03402898 0,09708267 ! cellular aromatic compound metabolic process GO:0006725 60 59 1,000 0,03402898 0,09693262 ! respiratory burst GO:0045730 7 7 0,000 0,03409902 0,09698223 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,03409902 0,0968328 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,03409902 0,09668383 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,03409902 0,09653531 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,03409902 0,09638725 ! regulation of chemokine production GO:0032642 7 7 0,000 0,03409902 0,09623964 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,03409902 0,09609249 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,03409902 0,09594578 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,03409902 0,09579952 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,03409902 0,09565371 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,03409902 0,09550834 ! gene silencing by RNA GO:0031047 7 7 0,000 0,03409902 0,09536341 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,03409902 0,09521892 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,03409902 0,09507487 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,03409902 0,09493125 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,03409902 0,09478807 ! axis specification GO:0009798 7 7 0,000 0,03409902 0,09464531 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,03409902 0,09450299 ! visual behavior GO:0007632 7 7 0,000 0,03409902 0,09436109 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,03409902 0,09421962 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,03409902 0,09407857 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,03409902 0,09393795 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,03409902 0,09379774 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,03409902 0,09365795 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,03409902 0,09351858 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,03409902 0,09337962 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,03409902 0,09324108 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,03409902 0,09310294 ! digestive system development GO:0055123 7 7 0,000 0,03409902 0,09296522 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,03409902 0,0928279 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,03409902 0,09269098 ! protein targeting to ER GO:0045047 8 7 0,000 0,03409902 0,09255447 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,03409902 0,09241836 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,03409902 0,09228265 ! endoderm development GO:0007492 7 7 0,000 0,03409902 0,09214734 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,03409902 0,09201243 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,03409902 0,09187791 GO:0006688|glycosphingolipid biosynthetic process, ! regulation of mRNA processing GO:0050684 7 7 0,000 0,03409902 0,09174378 ! response to hexose stimulus GO:0009746 7 7 0,000 0,03409902 0,09161004 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,03409902 0,09147669 GO:0033619|membrane protein proteolysis, ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,03409902 0,09134373 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 0,000 0,03409902 0,09121116 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,03409902 0,09107897 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,03409902 0,09094716 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,03409902 0,09081573 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,03409902 0,09068469 ! response to X-ray GO:0010165 7 7 0,000 0,03409902 0,09055402 ! regulation of intracellular pH GO:0051453 7 7 0,000 0,03409902 0,09042372 ! UV protection GO:0009650 7 7 0,000 0,03409902 0,0902938 ! DNA integration GO:0015074 7 7 0,000 0,03409902 0,09016426 ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,03409902 0,09003508 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,03409902 0,08990628 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,03409902 0,08977784 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,03409902 0,08964977 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,03409902 0,08952206 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,03409902 0,08939472 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,03409902 0,08926774 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,03409902 0,08914112 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,03409902 0,08901485 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,03409902 0,08888895 ! axon cargo transport GO:0008088 7 7 0,000 0,03409902 0,0887634 ! eating behavior GO:0042755 7 7 0,000 0,03409902 0,0886382 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,03409902 0,08851336 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,03409902 0,08838887 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,03409902 0,08826473 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,03409902 0,08814094 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,03409902 0,08801749 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,03409902 0,08789439 ! induction of an organ GO:0001759 7 7 0,000 0,03409902 0,08777163 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,03409902 0,08764922 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,03409902 0,08752714 ! autonomic nervous system development GO:0048483 7 7 0,000 0,03409902 0,08740541 ! intracellular lipid transport GO:0032365 7 7 0,000 0,03409902 0,08728401 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,03409902 0,08716295 ! platelet activation GO:0030168 8 7 0,000 0,03409902 0,08704223 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,03409902 0,08692184 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,03409902 0,08680178 ! natural killer cell activation GO:0030101 7 7 0,000 0,03409902 0,08668205 ! response to gamma radiation GO:0010332 8 7 0,000 0,03409902 0,08656265 ! NADP metabolic process GO:0006739 7 7 0,000 0,03409902 0,08644359 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,03409902 0,08632485 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,03409902 0,08620643 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,03409902 0,08608834 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,03409902 0,08597057 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,03409902 0,08585312 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,03409902 0,085736 ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,03409902 0,08561919 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,03409902 0,0855027 ! cell-cell recognition GO:0009988 8 7 0,000 0,03409902 0,08538653 ! hormone catabolic process GO:0042447 7 7 0,000 0,03409902 0,08527067 ! dopamine metabolic process GO:0042417 7 7 0,000 0,03409902 0,08515513 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,03409902 0,0850399 ! oxygen transport GO:0015671 7 7 0,000 0,03409902 0,08492498 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,03409902 0,08481037 ! regulation of mRNA stability GO:0043488 7 7 0,000 0,03409902 0,08469607 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,03409902 0,08458208 ! regulation of axon extension GO:0030516 7 7 0,000 0,03409902 0,0844684 ! cell killing GO:0001906 7 7 0,000 0,03409902 0,08435502 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,03409902 0,08424194 ! adult feeding behavior GO:0008343 7 7 0,000 0,03409902 0,08412917 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,03409902 0,08401669 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,03409902 0,08390452 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,03409902 0,08379265 ! negative regulation of T cell activation GO:0050868 7 7 0,000 0,03409902 0,08368107 ! response to cold GO:0009409 7 7 0,000 0,03409902 0,0835698 ! potassium ion transport GO:0006813 60 60 1,000 0,03509502 0,08589658 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 1,000 0,03509502 0,08578266 ! positive regulation of cellular protein metabolic process GO:0032270 61 61 1,000 0,03617404 0,088303 ! axonogenesis GO:0007409 66 62 1,000 0,0372659 0,09084796 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,03887723 0,09465089 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,03887723 0,09452603 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,03887723 0,09440149 ! positive regulation of translation GO:0045727 8 8 0,000 0,03887723 0,09427727 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,03887723 0,09415339 ! superoxide anion generation GO:0042554 8 8 0,000 0,03887723 0,09402983 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,03887723 0,09390659 ! cGMP metabolic process GO:0046068 8 8 0,000 0,03887723 0,09378367 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,03887723 0,09366108 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,03887723 0,09353881 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,03887723 0,09341685 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,03887723 0,09329522 ! negative regulation of bone remodeling GO:0046851 8 8 0,000 0,03887723 0,0931739 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,03887723 0,09305289 ! zinc ion transport GO:0006829 8 8 0,000 0,03887723 0,0929322 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,03887723 0,09281182 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,03887723 0,09269176 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,03887723 0,092572 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,03887723 0,09245255 ! lipid localization GO:0010876 8 8 0,000 0,03887723 0,09233341 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,03887723 0,09221458 ! response to cAMP GO:0051591 8 8 0,000 0,03887723 0,09209605 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,03887723 0,09197783 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,03887723 0,09185991 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,03887723 0,09174229 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,03887723 0,09162497 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,03887723 0,09150795 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,03887723 0,09139123 ! sensory perception of taste GO:0050909 8 8 0,000 0,03887723 0,09127481 ! organelle fusion GO:0048284 8 8 0,000 0,03887723 0,09115869 ! pancreas development GO:0031016 8 8 0,000 0,03887723 0,09104286 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,03887723 0,09092732 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,03887723 0,09081208 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,03887723 0,09069712 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,03887723 0,09058246 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,03887723 0,09046809 ! sperm motility GO:0030317 8 8 0,000 0,03887723 0,09035401 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,03887723 0,09024021 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,03887723 0,0901267 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,03887723 0,09001348 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,03887723 0,08990054 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,03887723 0,08978788 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,03887723 0,0896755 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,03887723 0,08956341 ! Golgi organization GO:0007030 8 8 0,000 0,03887723 0,08945159 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,03887723 0,08934006 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,03887723 0,0892288 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 0,03887723 0,08911782 ! fructose metabolic process GO:0006000 8 8 0,000 0,03887723 0,08900711 ! mannose metabolic process GO:0006013 9 8 0,000 0,03887723 0,08889668 ! NAD metabolic process GO:0019674 8 8 0,000 0,03887723 0,08878653 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,03887723 0,08867664 ! plasma membrane fusion GO:0045026 8 8 0,000 0,03887723 0,08856703 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 0,000 0,03887723 0,08845769 ! response to fungus GO:0009620 8 8 0,000 0,03887723 0,08834862 ! stem cell differentiation GO:0048863 8 8 0,000 0,03887723 0,08823981 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,03887723 0,08813128 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,03887723 0,08802301 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,03887723 0,087915 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,03887723 0,08780726 ! regulation of vasodilation GO:0042312 8 8 0,000 0,03887723 0,08769979 ! vasoconstriction GO:0042310 8 8 0,000 0,03887723 0,08759258 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,03887723 0,08748563 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,03887723 0,08737894 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,03887723 0,08727251 ! sensory perception of pain GO:0019233 8 8 0,000 0,03887723 0,08716633 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,03887723 0,08706042 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,03887723 0,08695477 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,03887723 0,08684937 ! chromatin silencing GO:0006342 8 8 0,000 0,03887723 0,08674422 ! tissue regeneration GO:0042246 8 8 0,000 0,03887723 0,08663933 ! salivary gland development GO:0007431 8 8 0,000 0,03887723 0,08653469 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,03887723 0,08643031 ! T cell homeostasis GO:0043029 8 8 0,000 0,03887723 0,08632618 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,03887723 0,0862223 ! peptidyl-serine modification GO:0018209 8 8 0,000 0,03887723 0,08611866 ! water homeostasis GO:0030104 8 8 0,000 0,03887723 0,08601528 ! cofactor transport GO:0051181 8 8 0,000 0,03887723 0,08591214 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,03887723 0,08580925 ! acid secretion GO:0046717 8 8 0,000 0,03887723 0,08570661 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 0,03887723 0,08560421 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,03887723 0,08550206 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,03887723 0,08540015 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,03887723 0,08529848 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,03887723 0,08519706 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,03887723 0,08509588 ! regulation of RNA stability GO:0043487 8 8 0,000 0,03887723 0,08499493 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,03887723 0,08489423 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,03887723 0,08479376 ! release of cytochrome c from mitochondria GO:0001836 9 8 0,000 0,03887723 0,08469353 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,03887723 0,08459354 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,03887723 0,08449378 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,03887723 0,08439426 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,03887723 0,08429497 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,03887723 0,08419592 ! developmental induction GO:0031128 8 8 0,000 0,03887723 0,0840971 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,03887723 0,08399851 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,03887723 0,08390015 ! actin filament polymerization GO:0030041 9 8 0,000 0,03887723 0,08380202 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 0,03887723 0,08370412 ! peptide hormone processing GO:0016486 8 8 0,000 0,03887723 0,08360645 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,03887723 0,08350901 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,03887723 0,08341179 ! positive regulation of protein metabolic process GO:0051247 64 64 1,000 0,03948755 0,08462274 ! regulation of hormone levels GO:0010817 66 65 1,000 0,04061705 0,08694219 ! negative regulation of protein metabolic process GO:0051248 66 66 1,000 0,04175882 0,08928248 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 1,000 0,0429127 0,09164323 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! lactation GO:0007595 10 9 0,000 0,04363249 0,09307254 ! embryonic pattern specification GO:0009880 10 9 0,000 0,04363249 0,09296495 ! positive regulation of cell size GO:0045793 9 9 0,000 0,04363249 0,0928576 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,04363249 0,09275049 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,04363249 0,09264364 ! negative regulation of cell cycle process GO:0010948 9 9 0,000 0,04363249 0,09253703 ! viral genome replication GO:0019079 9 9 0,000 0,04363249 0,09243067 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,04363249 0,09232455 ! copper ion transport GO:0006825 9 9 0,000 0,04363249 0,09221867 ! lipid phosphorylation GO:0046834 9 9 0,000 0,04363249 0,09211303 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,04363249 0,09200764 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,04363249 0,09190249 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,04363249 0,09179758 ! RNA polyadenylation GO:0043631 9 9 0,000 0,04363249 0,09169291 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,04363249 0,09158847 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,04363249 0,09148428 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,04363249 0,09138032 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,04363249 0,09127659 ! phospholipid efflux GO:0033700 9 9 0,000 0,04363249 0,09117311 ! response to alkaloid GO:0043279 10 9 0,000 0,04363249 0,09106985 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,04363249 0,09096683 GO:0042107|cytokine metabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 9 9 0,000 0,04363249 0,09086404 ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,04363249 0,09076149 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,04363249 0,09065916 ! response to ethanol GO:0045471 9 9 0,000 0,04363249 0,09055707 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,04363249 0,09045521 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,04363249 0,09035357 ! methionine metabolic process GO:0006555 9 9 0,000 0,04363249 0,09025216 ! glutamine metabolic process GO:0006541 9 9 0,000 0,04363249 0,09015099 ! cerebral cortex development GO:0021987 9 9 0,000 0,04363249 0,09005003 ! response to osmotic stress GO:0006970 9 9 0,000 0,04363249 0,08994931 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,04363249 0,0898488 ! central nervous system neuron development GO:0021954 10 9 0,000 0,04363249 0,08974853 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,04363249 0,08964847 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,04363249 0,08954864 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,04363249 0,08944903 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,04363249 0,08934964 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,04363249 0,08925048 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,04363249 0,08915153 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,04363249 0,0890528 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,04363249 0,08895429 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,04363249 0,088856 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,04363249 0,08875792 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,04363249 0,08866006 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,04363249 0,08856242 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,04363249 0,08846499 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,04363249 0,08836778 ! positive regulation of protein import into nucleus GO:0042307 9 9 0,000 0,04363249 0,08827078 ! DNA replication initiation GO:0006270 9 9 0,000 0,04363249 0,08817399 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,04363249 0,08807741 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,04363249 0,08798105 ! regulation of cellular pH GO:0030641 9 9 0,000 0,04363249 0,08788489 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,04363249 0,08778895 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,04363249 0,08769322 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,04363249 0,08759769 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,04363249 0,08750237 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,04363249 0,08740726 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,04363249 0,08731235 ! negative regulation of tissue remodeling GO:0034104 9 9 0,000 0,04363249 0,08721766 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,04363249 0,08712316 ! regulation of leukocyte migration GO:0002685 9 9 0,000 0,04363249 0,08702887 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,04363249 0,08693479 ! collagen catabolic process GO:0030574 9 9 0,000 0,04363249 0,08684091 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,04363249 0,08674723 ! purine base metabolic process GO:0006144 9 9 0,000 0,04363249 0,08665375 ! gas transport GO:0015669 9 9 0,000 0,04363249 0,08656047 ! cholesterol efflux GO:0033344 9 9 0,000 0,04363249 0,0864674 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,04363249 0,08637452 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,04363249 0,08628184 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,04363249 0,08618937 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,04363249 0,08609709 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 0,000 0,04363249 0,086005 ! defense response to virus GO:0051607 9 9 0,000 0,04363249 0,08591312 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,04363249 0,08582143 ! actin filament-based movement GO:0030048 9 9 0,000 0,04363249 0,08572993 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,04363249 0,08563864 ! response to radiation GO:0009314 70 68 1,000 0,04407857 0,08642213 ! regionalization GO:0003002 70 69 1,000 0,04525627 0,08863689 ! cell part morphogenesis GO:0032990 75 70 1,000 0,04644569 0,09086985 ! wound healing GO:0042060 74 70 1,000 0,04644569 0,09077349 ! calcium ion homeostasis GO:0055074 71 71 1,000 0,04764667 0,09302204 GO:0006874|cellular calcium ion homeostasis, ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,04836492 0,09432438 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,04836492 0,09422467 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,04836492 0,09412517 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,04836492 0,09402589 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,04836492 0,09392681 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,04836492 0,09382794 ! neuron maturation GO:0042551 10 10 0,000 0,04836492 0,09372927 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,04836492 0,09363082 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,04836492 0,09353257 GO:0045767|regulation of anti-apoptosis, ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,04836492 0,09343453 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,04836492 0,09333669 ! hormone secretion GO:0046879 10 10 0,000 0,04836492 0,09323906 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,04836492 0,09314163 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,04836492 0,0930444 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 0,000 0,04836492 0,09294738 ! cAMP metabolic process GO:0046058 10 10 0,000 0,04836492 0,09285056 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,04836492 0,09275394 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,04836492 0,09265752 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,04836492 0,09256131 ! glial cell development GO:0021782 10 10 0,000 0,04836492 0,09246529 ! phototransduction GO:0007602 11 10 0,000 0,04836492 0,09236947 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,04836492 0,09227385 ! apoptotic mitochondrial changes GO:0008637 11 10 0,000 0,04836492 0,09217843 ! fat cell differentiation GO:0045444 10 10 0,000 0,04836492 0,0920832 ! myoblast differentiation GO:0045445 10 10 0,000 0,04836492 0,09198817 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,04836492 0,09189334 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,04836492 0,0917987 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,04836492 0,09170426 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,04836492 0,09161001 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,04836492 0,09151595 ! protein polyubiquitination GO:0000209 10 10 0,000 0,04836492 0,09142209 ! glutamate metabolic process GO:0006536 11 10 0,000 0,04836492 0,09132842 ! plasma membrane organization GO:0007009 10 10 0,000 0,04836492 0,09123494 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,04836492 0,09114166 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-substrate junction assembly GO:0007044 11 10 0,000 0,04836492 0,09104856 ! lysosomal transport GO:0007041 10 10 0,000 0,04836492 0,09095565 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,04836492 0,09086293 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,04836492 0,09077041 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,04836492 0,09067807 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,04836492 0,09058591 ! exocrine system development GO:0035272 10 10 0,000 0,04836492 0,09049395 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,04836492 0,09040217 ! neuromuscular junction development GO:0007528 10 10 0,000 0,04836492 0,09031058 ! embryo implantation GO:0007566 11 10 0,000 0,04836492 0,09021917 ! regulation of protein binding GO:0043393 11 10 0,000 0,04836492 0,09012795 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,04836492 0,09003691 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,04836492 0,08994605 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,04836492 0,08985538 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,04836492 0,08976489 ! negative regulation of immune response GO:0050777 10 10 0,000 0,04836492 0,08967459 ! cytolysis GO:0019835 10 10 0,000 0,04836492 0,08958446 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,04836492 0,08949452 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,04836492 0,08940475 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,04836492 0,08931517 ! histone deacetylation GO:0016575 10 10 0,000 0,04836492 0,08922576 ! mRNA splice site selection GO:0006376 11 10 0,000 0,04836492 0,08913654 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,04836492 0,08904749 ! gland morphogenesis GO:0022612 10 10 0,000 0,04836492 0,08895862 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,04836492 0,08886993 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,04836492 0,08878141 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,04836492 0,08869307 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,04836492 0,08860491 ! regulation of epidermis development GO:0045682 10 10 0,000 0,04836492 0,08851692 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,04836492 0,08842911 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,04836492 0,08834147 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,04836492 0,088254 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,04836492 0,08816671 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,04836492 0,08807958 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 0,04836492 0,08799263 ! gut development GO:0048565 10 10 0,000 0,04836492 0,08790586 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,04836492 0,08781925 ! positive regulation of neuron apoptosis GO:0043525 10 10 0,000 0,04836492 0,08773281 ! negative regulation of homeostatic process GO:0032845 10 10 0,000 0,04836492 0,08764655 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,04836492 0,08756045 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,04836492 0,08747452 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,04836492 0,08738876 ! positive regulation of hydrolase activity GO:0051345 72 72 1,000 0,04885908 0,08819519 ! protein secretion GO:0009306 11 11 0,000 0,05307461 0,09571086 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,05307461 0,09561731 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,05307461 0,09552393 ! negative regulation of defense response GO:0031348 11 11 0,000 0,05307461 0,09543074 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,05307461 0,09533772 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,05307461 0,09524489 ! skin development GO:0043588 11 11 0,000 0,05307461 0,09515224 ! signal complex assembly GO:0007172 11 11 0,000 0,05307461 0,09505977 ! microtubule-based transport GO:0010970 11 11 0,000 0,05307461 0,09496748 ! peroxisomal transport GO:0043574 11 11 0,000 0,05307461 0,09487537 ! protein amino acid methylation GO:0006479 11 11 0,000 0,05307461 0,09478343 GO:0008213|protein amino acid alkylation, ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 0,000 0,05307461 0,09469168 GO:0032388|positive regulation of intracellular transport, ! heart contraction GO:0060047 11 11 0,000 0,05307461 0,0946001 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,05307461 0,0945087 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,05307461 0,09441747 ! T cell proliferation GO:0042098 11 11 0,000 0,05307461 0,09432643 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,05307461 0,09423555 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,05307461 0,09414485 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,05307461 0,09405433 ! spinal cord development GO:0021510 11 11 0,000 0,05307461 0,09396398 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,05307461 0,0938738 ! smooth muscle contraction GO:0006939 11 11 0,000 0,05307461 0,0937838 ! cellular response to starvation GO:0009267 11 11 0,000 0,05307461 0,09369397 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,05307461 0,09360431 ! digestive system process GO:0022600 11 11 0,000 0,05307461 0,09351482 ! fucose metabolic process GO:0006004 11 11 0,000 0,05307461 0,0934255 ! membrane budding GO:0006900 11 11 0,000 0,05307461 0,09333636 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,05307461 0,09324738 ! monoamine transport GO:0015844 11 11 0,000 0,05307461 0,09315857 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,05307461 0,09306994 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,05307461 0,09298147 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 0,000 0,05307461 0,09289317 ! body fluid secretion GO:0007589 11 11 0,000 0,05307461 0,09280503 ! G1/S transition checkpoint GO:0031575 12 11 0,000 0,05307461 0,09271707 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,05307461 0,09262926 ! intermediate filament-based process GO:0045103 11 11 0,000 0,05307461 0,09254163 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,05307461 0,09245416 GO:0060415|muscle tissue morphogenesis, ! membrane depolarization GO:0051899 11 11 0,000 0,05307461 0,09236686 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,05307461 0,09227972 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,05307461 0,09219275 ! oogenesis GO:0048477 11 11 0,000 0,05307461 0,09210594 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,05307461 0,09201929 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,05307461 0,0919328 ! vitamin transport GO:0051180 11 11 0,000 0,05307461 0,09184648 ! muscle maintenance GO:0046716 12 11 0,000 0,05307461 0,09176032 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,05307461 0,09167432 ! hindbrain development GO:0030902 11 11 0,000 0,05307461 0,09158849 ! steroid catabolic process GO:0006706 11 11 0,000 0,05307461 0,09150281 ! endocrine process GO:0050886 11 11 0,000 0,05307461 0,09141729 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,05307461 0,09133194 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,05307461 0,09124674 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,05307461 0,0911617 ! negative regulation of lymphocyte activation GO:0051250 11 11 0,000 0,05307461 0,09107682 ! cellular metal ion homeostasis GO:0006875 77 77 1,000 0,05508794 0,09444379 ! cell morphogenesis involved in differentiation GO:0000904 82 77 1,000 0,05508794 0,09435602 ! metal ion homeostasis GO:0055065 78 78 1,000 0,05636615 0,09645572 ! nuclear transport GO:0051169 79 79 1,000 0,05765486 0,09856949 GO:0006913|nucleocytoplasmic transport, ! positive regulation of protein catabolic process GO:0045732 12 12 0,000 0,05776168 0,09866058 ! translational initiation GO:0006413 12 12 0,000 0,05776168 0,09856923 ! initiation of viral infection GO:0019059 12 12 0,000 0,05776168 0,09847805 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,05776168 0,09838703 ! iron ion transport GO:0006826 13 12 0,000 0,05776168 0,09829618 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,05776168 0,09820551 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,05776168 0,09811499 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,05776168 0,09802465 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,05776168 0,09793447 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,05776168 0,09784446 ! collagen metabolic process GO:0032963 12 12 0,000 0,05776168 0,09775461 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,05776168 0,09766492 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,05776168 0,09757541 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,05776168 0,09748605 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,05776168 0,09739686 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,05776168 0,09730783 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,05776168 0,09721897 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,05776168 0,09713026 ! retinoid metabolic process GO:0001523 12 12 0,000 0,05776168 0,09704172 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,05776168 0,09695334 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,05776168 0,09686512 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,05776168 0,09677706 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,05776168 0,09668916 ! acute-phase response GO:0006953 12 12 0,000 0,05776168 0,09660142 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,05776168 0,09651384 ! vacuolar transport GO:0007034 12 12 0,000 0,05776168 0,09642642 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,05776168 0,09633916 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,05776168 0,09625205 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,05776168 0,0961651 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,05776168 0,09607831 ! male gonad development GO:0008584 12 12 0,000 0,05776168 0,09599168 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,05776168 0,0959052 ! renal system process GO:0003014 12 12 0,000 0,05776168 0,09581887 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,05776168 0,09573271 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,05776168 0,09564669 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,05776168 0,09556083 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,05776168 0,09547513 ! pallium development GO:0021543 13 12 0,000 0,05776168 0,09538958 ! cell fate determination GO:0001709 12 12 0,000 0,05776168 0,09530418 ! regulation of chromosome organization GO:0033044 12 12 0,000 0,05776168 0,09521893 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,05776168 0,09513384 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,05776168 0,0950489 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,05776168 0,09496411 ! detection of light stimulus GO:0009583 13 12 0,000 0,05776168 0,09487947 ! synaptogenesis GO:0007416 12 12 0,000 0,05776168 0,09479499 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,05776168 0,09471065 ! hormone transport GO:0009914 12 12 0,000 0,05776168 0,09462646 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,05776168 0,09454242 ! heme biosynthetic process GO:0006783 12 12 0,000 0,05776168 0,09445853 ! spermatid differentiation GO:0048515 13 12 0,000 0,05776168 0,09437479 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,05776168 0,0942912 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,05776168 0,09420776 ! neural tube closure GO:0001843 13 12 0,000 0,05776168 0,09412446 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,05776168 0,09404131 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 0,000 0,05776168 0,09395831 ! tube development GO:0035295 83 81 1,000 0,06026331 0,09794117 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 0,000 0,06242622 0,10136698 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,06242622 0,10127775 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,06242622 0,10118868 ! phenol metabolic process GO:0018958 13 13 0,000 0,06242622 0,10109976 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! gluconeogenesis GO:0006094 13 13 0,000 0,06242622 0,101011 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,06242622 0,10092239 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,06242622 0,10083394 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,06242622 0,10074565 ! regeneration GO:0031099 13 13 0,000 0,06242622 0,1006575 ! keratinization GO:0031424 13 13 0,000 0,06242622 0,10056952 ! post-embryonic development GO:0009791 14 13 0,000 0,06242622 0,10048168 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,06242622 0,100394 ! patterning of blood vessels GO:0001569 13 13 0,000 0,06242622 0,10030647 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,06242622 0,1002191 ! regulation of innate immune response GO:0045088 13 13 0,000 0,06242622 0,10013188 ! mitochondrial membrane organization GO:0007006 13 13 0,000 0,06242622 0,10004481 ! negative regulation of DNA replication GO:0008156 13 13 0,000 0,06242622 0,09995789 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,06242622 0,09987112 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,06242622 0,0997845 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,06242622 0,09969803 ! autophagy GO:0006914 13 13 0,000 0,06242622 0,09961171 ! receptor metabolic process GO:0043112 14 13 0,000 0,06242622 0,09952554 ! actin filament bundle formation GO:0051017 13 13 0,000 0,06242622 0,09943952 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,06242622 0,09935365 ! ureteric bud development GO:0001657 13 13 0,000 0,06242622 0,09926793 ! cell aging GO:0007569 13 13 0,000 0,06242622 0,09918235 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 0,000 0,06242622 0,09909692 ! regulation of endothelial cell migration GO:0010594 13 13 0,000 0,06242622 0,09901164 ! response to endoplasmic reticulum stress GO:0034976 13 13 0,000 0,06242622 0,09892651 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,06242622 0,09884152 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,06242622 0,09875668 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of viral reproduction GO:0050792 13 13 0,000 0,06242622 0,09867198 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,06242622 0,09858743 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,06242622 0,09850302 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,06242622 0,09841876 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,06242622 0,09833464 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,06242622 0,09825066 ! vasodilation GO:0042311 14 13 0,000 0,06242622 0,09816683 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,06242622 0,09808314 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,06242622 0,0979996 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,06242622 0,09791619 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 0,06242622 0,09783293 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 0,000 0,06242622 0,09774981 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,06242622 0,09766683 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,06242622 0,09758399 ! immunoglobulin production GO:0002377 13 13 0,000 0,06242622 0,09750129 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,06242622 0,09741874 ! negative regulation of intracellular transport GO:0032387 13 13 0,000 0,06242622 0,09733632 ! negative regulation of leukocyte activation GO:0002695 13 13 0,000 0,06242622 0,09725404 ! cell-cell junction organization GO:0045216 13 13 0,000 0,06242622 0,0971719 ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,06242622 0,0970899 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,06242622 0,09700803 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,06242622 0,09692631 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,06242622 0,09684472 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,06242622 0,09676327 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,06242622 0,09668196 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,06242622 0,09660078 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,06242622 0,09651974 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,06242622 0,09643883 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,06242622 0,09635806 ! blastocyst development GO:0001824 13 13 0,000 0,06242622 0,09627743 ! telomere organization GO:0032200 13 13 0,000 0,06242622 0,09619693 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,06242622 0,09611656 ! regulation of amine transport GO:0051952 13 13 0,000 0,06242622 0,09603633 ! tissue homeostasis GO:0001894 13 13 0,000 0,06242622 0,09595624 GO:0048871|multicellular organismal homeostasis, ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,06242622 0,09587627 ! regulation of cellular localization GO:0060341 86 85 1,000 0,06560074 0,10066791 ! positive regulation of cell differentiation GO:0045597 87 85 1,000 0,06560074 0,10058416 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 1,000 0,06695948 0,10258215 ! organophosphate metabolic process GO:0019637 87 86 1,000 0,06695948 0,10249695 GO:0006644|phospholipid metabolic process, ! neuron fate commitment GO:0048663 14 14 0,000 0,06706835 0,1025784 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,06706835 0,10249334 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,06706835 0,10240843 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,06706835 0,10232365 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,06706835 0,10223902 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,06706835 0,10215452 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,06706835 0,10207017 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,06706835 0,10198595 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,06706835 0,10190187 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,06706835 0,10181793 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,06706835 0,10173413 ! vesicle docking GO:0048278 14 14 0,000 0,06706835 0,10165047 ! superoxide metabolic process GO:0006801 15 14 0,000 0,06706835 0,10156695 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,06706835 0,10148356 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,06706835 0,10140031 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,06706835 0,10131719 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,06706835 0,10123421 ! hair cycle GO:0042633 14 14 0,000 0,06706835 0,10115137 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,06706835 0,10106866 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,06706835 0,10098609 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,06706835 0,10090365 ! lysosome organization GO:0007040 14 14 0,000 0,06706835 0,10082135 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,06706835 0,10073918 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,06706835 0,10065714 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,06706835 0,10057524 GO:0045936|negative regulation of phosphate metabolic process, ! primary neural tube formation GO:0014020 15 14 0,000 0,06706835 0,10049347 ! peptide cross-linking GO:0018149 14 14 0,000 0,06706835 0,10041184 ! regulation of behavior GO:0050795 14 14 0,000 0,06706835 0,10033034 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,06706835 0,10024896 ! base-excision repair GO:0006284 14 14 0,000 0,06706835 0,10016773 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,06706835 0,10008662 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,06706835 0,10000564 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,06706835 0,0999248 ! formation of primary germ layer GO:0001704 14 14 0,000 0,06706835 0,09984408 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,06706835 0,0997635 ! collagen fibril organization GO:0030199 14 14 0,000 0,06706835 0,09968304 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,06706835 0,09960272 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,06706835 0,09952252 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,06706835 0,09944246 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,06706835 0,09936252 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,06706835 0,09928271 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,06706835 0,09920303 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,06706835 0,09912347 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,06706835 0,09904405 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,06706835 0,09896475 ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 1,000 0,07109229 0,10481847 ! protein import into nucleus, translocation GO:0000060 15 15 0,000 0,07168817 0,10561255 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,07168817 0,10552819 ! positive regulation of ossification GO:0045778 15 15 0,000 0,07168817 0,10544397 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,07168817 0,10535989 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,07168817 0,10527594 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,07168817 0,10519212 ! response to vitamin GO:0033273 15 15 0,000 0,07168817 0,10510843 ! regulation of transcription factor import into nucleus GO:0042990 15 15 0,000 0,07168817 0,10502488 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,07168817 0,10494146 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,07168817 0,10485817 ! ovarian follicle development GO:0001541 15 15 0,000 0,07168817 0,10477502 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,07168817 0,104692 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,07168817 0,1046091 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,07168817 0,10452634 ! ER-nuclear signaling pathway GO:0006984 15 15 0,000 0,07168817 0,10444371 ! heme metabolic process GO:0042168 15 15 0,000 0,07168817 0,10436122 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,07168817 0,10427885 ! chromosome condensation GO:0030261 15 15 0,000 0,07168817 0,10419661 ! response to starvation GO:0042594 15 15 0,000 0,07168817 0,1041145 ! response to ionizing radiation GO:0010212 16 15 0,000 0,07168817 0,10403252 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,07168817 0,10395067 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,07168817 0,10386895 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,07168817 0,10378735 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,07168817 0,10370589 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,07168817 0,10362455 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,07168817 0,10354334 ! phospholipid transport GO:0015914 15 15 0,000 0,07168817 0,10346225 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,07168817 0,1033813 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,07168817 0,10330047 ! glutathione metabolic process GO:0006749 16 15 0,000 0,07168817 0,10321976 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,07168817 0,10313919 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,07168817 0,10305874 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,07168817 0,10297841 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,07168817 0,10289821 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,07168817 0,10281813 ! negative regulation of cell activation GO:0050866 15 15 0,000 0,07168817 0,10273818 ! protein homooligomerization GO:0051260 15 15 0,000 0,07168817 0,10265835 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,07168817 0,10257865 ! regulation of Ras protein signal transduction GO:0046578 90 90 1,000 0,07248836 0,10364316 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 1,000 0,07389345 0,10557026 ! DNA replication GO:0006260 91 91 1,000 0,07389345 0,10548848 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,07628578 0,10881942 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,07628578 0,10873526 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,07628578 0,10865123 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,07628578 0,10856733 ! learning GO:0007612 16 16 0,000 0,07628578 0,10848356 ! circadian rhythm GO:0007623 16 16 0,000 0,07628578 0,10839992 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,07628578 0,10831641 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 0,000 0,07628578 0,10823302 ! vacuole organization GO:0007033 16 16 0,000 0,07628578 0,10814977 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,07628578 0,10806664 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,07628578 0,10798364 ! vesicle targeting GO:0006903 17 16 0,000 0,07628578 0,10790076 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,07628578 0,10781802 ! iron ion homeostasis GO:0055072 16 16 0,000 0,07628578 0,1077354 ! positive regulation of cell development GO:0010720 16 16 0,000 0,07628578 0,10765291 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,07628578 0,10757054 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,07628578 0,1074883 ! cell fate specification GO:0001708 16 16 0,000 0,07628578 0,10740619 ! pentose metabolic process GO:0019321 16 16 0,000 0,07628578 0,1073242 ! fatty acid transport GO:0015908 16 16 0,000 0,07628578 0,10724233 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,07628578 0,10716059 ! cellular response to nutrient levels GO:0031669 16 16 0,000 0,07628578 0,10707898 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,07628578 0,10699749 ! cofactor catabolic process GO:0051187 16 16 0,000 0,07628578 0,10691612 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,07628578 0,10683488 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,07628578 0,10675376 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,07628578 0,10667276 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,07628578 0,10659189 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,07628578 0,10651113 GO:0001841|neural tube formation, ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,07628578 0,1064305 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,07628578 0,10635 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,07628578 0,10626961 ! regulation of coagulation GO:0050818 17 16 0,000 0,07628578 0,10618935 ! pattern specification process GO:0007389 96 94 1,000 0,07816177 0,1087186 ! epidermis development GO:0008544 94 94 1,000 0,07816177 0,10863661 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,08086129 0,11230396 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 0,000 0,08086129 0,1122194 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,08086129 0,11213496 ! myelination GO:0042552 17 17 0,000 0,08086129 0,11205064 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,08086129 0,11196646 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,08086129 0,1118824 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,08086129 0,11179847 ! leukocyte adhesion GO:0007159 17 17 0,000 0,08086129 0,11171466 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,08086129 0,11163098 ! sensory perception of smell GO:0007608 17 17 0,000 0,08086129 0,11154742 ! glucose transport GO:0015758 17 17 0,000 0,08086129 0,11146399 ! cell junction assembly GO:0034329 18 17 0,000 0,08086129 0,11138069 ! tissue remodeling GO:0048771 17 17 0,000 0,08086129 0,1112975 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,08086129 0,11121445 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,08086129 0,11113151 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,08086129 0,1110487 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,08086129 0,11096601 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,08086129 0,11088345 ! neural crest cell development GO:0014032 19 17 0,000 0,08086129 0,11080101 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 0,08086129 0,11071869 ! negative regulation of cell development GO:0010721 18 17 0,000 0,08086129 0,11063649 GO:0050768|negative regulation of neurogenesis, ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,08086129 0,11055442 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,08086129 0,11047247 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,08086129 0,11039063 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,08086129 0,11030892 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,08086129 0,11022734 ! adult locomotory behavior GO:0008344 17 17 0,000 0,08086129 0,11014587 ! embryonic organ development GO:0048568 17 17 0,000 0,08086129 0,11006452 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,08086129 0,10998329 ! liver development GO:0001889 17 17 0,000 0,08086129 0,10990218 ! gene silencing GO:0016458 17 17 0,000 0,08086129 0,10982119 ! regulation of cell growth GO:0001558 97 96 1,000 0,08105036 0,10999691 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,0854148 0,11583478 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,0854148 0,11574961 ! meiosis I GO:0007127 18 18 0,000 0,0854148 0,11566456 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,0854148 0,11557964 ! membrane docking GO:0022406 18 18 0,000 0,0854148 0,11549484 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,0854148 0,11541017 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,0854148 0,11532562 GO:0070661|leukocyte proliferation, ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,0854148 0,11524119 ! hexose transport GO:0008645 18 18 0,000 0,0854148 0,11515689 GO:0015749|monosaccharide transport, ! cholesterol homeostasis GO:0042632 18 18 0,000 0,0854148 0,11507271 GO:0055092|sterol homeostasis, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 0,000 0,0854148 0,11498866 ! striated muscle contraction GO:0006941 18 18 0,000 0,0854148 0,11490472 ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,0854148 0,11482091 ! ceramide metabolic process GO:0006672 18 18 0,000 0,0854148 0,11473722 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,0854148 0,11465366 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,0854148 0,11457021 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,0854148 0,11448689 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,0854148 0,11440368 ! B cell differentiation GO:0030183 18 18 0,000 0,0854148 0,1143206 ! cellular response to extracellular stimulus GO:0031668 18 18 0,000 0,0854148 0,11423764 ! ensheathment of neurons GO:0007272 18 18 0,000 0,0854148 0,1141548 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 18 18 0,000 0,0854148 0,11407208 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,0854148 0,11398948 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,0854148 0,113907 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,0854148 0,11382463 ! ectoderm development GO:0007398 99 99 1,000 0,08544553 0,11378332 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 1,000 0,08692676 0,11567221 ! response to other organism GO:0051707 101 100 1,000 0,08692676 0,11558875 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,0899464 0,11951783 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,0899464 0,11943172 GO:0006956|complement activation, ! negative regulation of DNA metabolic process GO:0051053 19 19 0,000 0,0899464 0,11934573 ! regulation of pH GO:0006885 19 19 0,000 0,0899464 0,11925987 ! feeding behavior GO:0007631 19 19 0,000 0,0899464 0,11917414 ! regulation of endothelial cell proliferation GO:0001936 19 19 0,000 0,0899464 0,11908852 ! peroxisome organization GO:0007031 19 19 0,000 0,0899464 0,11900303 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,0899464 0,11891766 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,0899464 0,11883242 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,0899464 0,1187473 ! metanephros development GO:0001656 19 19 0,000 0,0899464 0,11866229 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,0899464 0,11857741 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,0899464 0,11849265 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,0899464 0,11840802 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,0899464 0,1183235 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,0899464 0,1182391 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,0899464 0,11815483 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,0899464 0,11807067 ! dorsal/ventral pattern formation GO:0009953 19 19 0,000 0,0899464 0,11798664 ! eye morphogenesis GO:0048592 19 19 0,000 0,0899464 0,11790272 ! regulation of cell shape GO:0008360 21 19 0,000 0,0899464 0,11781892 ! placenta development GO:0001890 19 19 0,000 0,0899464 0,11773524 ! vesicle localization GO:0051648 20 19 0,000 0,0899464 0,11765168 ! regulation of muscle development GO:0048634 21 20 0,000 0,09445622 0,12346298 ! negative regulation of binding GO:0051100 21 20 0,000 0,09445622 0,12337548 ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,09445622 0,12328811 ! neural tube development GO:0021915 21 20 0,000 0,09445622 0,12320086 ! nucleus organization GO:0006997 20 20 0,000 0,09445622 0,12311373 ! phagocytosis GO:0006909 21 20 0,000 0,09445622 0,12302672 ! positive regulation of gene-specific transcription GO:0043193 20 20 0,000 0,09445622 0,12293984 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,09445622 0,12285308 ! protein targeting to membrane GO:0006612 22 20 0,000 0,09445622 0,12276644 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,09445622 0,12267992 ! chromatin remodeling GO:0006338 20 20 0,000 0,09445622 0,12259353 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,09445622 0,12250725 ! lipid oxidation GO:0034440 20 20 0,000 0,09445622 0,1224211 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,09445622 0,12233507 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,09445622 0,12224916 ! RNA modification GO:0009451 20 20 0,000 0,09445622 0,12216337 ! single fertilization GO:0007338 21 20 0,000 0,09445622 0,12207771 ! regulation of B cell activation GO:0050864 20 20 0,000 0,09445622 0,12199216 ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,09894434 0,12769917 ! mRNA catabolic process GO:0006402 21 21 0,000 0,09894434 0,1276098 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,09894434 0,12752057 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! mammary gland development GO:0030879 23 21 0,000 0,09894434 0,12743145 ! protein amino acid lipidation GO:0006497 21 21 0,000 0,09894434 0,12734246 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,09894434 0,1272536 ! Notch signaling pathway GO:0007219 22 21 0,000 0,09894434 0,12716486 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,09894434 0,12707624 ! ear morphogenesis GO:0042471 21 21 0,000 0,09894434 0,12698775 ! organic anion transport GO:0015711 21 21 0,000 0,09894434 0,12689938 ! cholesterol transport GO:0030301 21 21 0,000 0,09894434 0,12681113 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,09894434 0,12672301 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,09894434 0,12663501 GO:0032313|regulation of Rab GTPase activity, ! regulation of protein import into nucleus GO:0042306 21 21 0,000 0,09894434 0,12654713 ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,09894434 0,12645937 ! regulation of action potential in neuron GO:0019228 21 21 0,000 0,09894434 0,12637173 ! regulation of proteolysis GO:0030162 21 21 0,000 0,09894434 0,12628422 ! negative regulation of hydrolase activity GO:0051346 21 21 0,000 0,09894434 0,12619682 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,09894434 0,12610955 ! negative regulation of protein transport GO:0051224 21 21 0,000 0,09894434 0,1260224 ! RNA export from nucleus GO:0006405 22 22 0,000 0,10341086 0,13162031 ! sister chromatid segregation GO:0000819 22 22 0,000 0,10341086 0,13152948 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,10341086 0,13143877 ! regulation of ion transport GO:0043269 22 22 0,000 0,10341086 0,13134818 ! odontogenesis GO:0042476 22 22 0,000 0,10341086 0,13125772 ! cell junction organization GO:0034330 23 22 0,000 0,10341086 0,13116739 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,10341086 0,13107718 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! embryonic skeletal system development GO:0048706 22 22 0,000 0,10341086 0,13098709 ! maintenance of protein location in cell GO:0032507 23 22 0,000 0,10341086 0,13089713 ! ovulation cycle process GO:0022602 22 22 0,000 0,10341086 0,13080729 ! cell chemotaxis GO:0060326 23 22 0,000 0,10341086 0,13071757 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,10341086 0,13062797 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,10341086 0,1305385 ! male sex differentiation GO:0046661 22 22 0,000 0,10341086 0,13044915 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,10341086 0,13035993 ! biopolymer methylation GO:0043414 22 22 0,000 0,10341086 0,13027082 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,10341086 0,13018184 ! detection of external stimulus GO:0009581 23 22 0,000 0,10341086 0,13009298 ! neuron migration GO:0001764 22 22 0,000 0,10341086 0,13000424 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,10341086 0,12991562 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,10341086 0,12982712 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,10341086 0,12973874 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,10341086 0,12965049 ! aerobic respiration GO:0009060 22 22 0,000 0,10341086 0,12956235 ! cytokine production GO:0001816 22 22 0,000 0,10341086 0,12947433 ! cytokinesis GO:0000910 23 22 0,000 0,10341086 0,12938643 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,10341086 0,12929865 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,10785589 0,13476502 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,10785589 0,13467372 ! viral infectious cycle GO:0019058 23 23 0,000 0,10785589 0,13458254 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,10785589 0,13449148 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,10785589 0,13440055 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,10785589 0,13430974 ! mitotic cell cycle checkpoint GO:0007093 24 23 0,000 0,10785589 0,13421905 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,10785589 0,13412848 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,10785589 0,13403804 ! endocrine system development GO:0035270 23 23 0,000 0,10785589 0,13394771 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,10785589 0,13385751 ! female gonad development GO:0008585 23 23 0,000 0,10785589 0,13376744 ! monovalent inorganic cation homeostasis GO:0055067 23 23 0,000 0,10785589 0,13367748 ! lipid homeostasis GO:0055088 23 23 0,000 0,10785589 0,13358764 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,10785589 0,13349792 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,10785589 0,13340833 ! mitochondrial transport GO:0006839 24 24 0,000 0,11227953 0,13878684 ! regulation of action potential GO:0001508 24 24 0,000 0,11227953 0,13869382 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,11227953 0,13860092 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,11227953 0,13850815 ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,11227953 0,1384155 ! T cell differentiation GO:0030217 24 24 0,000 0,11227953 0,13832298 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,11227953 0,13823058 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,11227953 0,1381383 ! ovulation cycle GO:0042698 24 24 0,000 0,11227953 0,13804615 ! fertilization GO:0009566 25 24 0,000 0,11227953 0,13795412 ! maintenance of protein location GO:0045185 25 24 0,000 0,11227953 0,13786221 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,11227953 0,13777042 ! androgen receptor signaling pathway GO:0030521 24 24 0,000 0,11227953 0,13767876 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,11227953 0,13758722 ! glucan metabolic process GO:0044042 25 24 0,000 0,11227953 0,1374958 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,11668188 0,14279197 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,11668188 0,14269722 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,11668188 0,14260259 ! cellular component disassembly GO:0022411 26 25 0,000 0,11668188 0,14250809 ! endosome transport GO:0016197 25 25 0,000 0,11668188 0,14241371 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,11668188 0,14231946 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,11668188 0,14222533 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,11668188 0,14213133 ! regulation of T cell proliferation GO:0042129 25 25 0,000 0,11668188 0,14203745 ! excretion GO:0007588 25 25 0,000 0,11668188 0,1419437 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,11668188 0,14185007 ! gastrulation GO:0007369 25 25 0,000 0,11668188 0,14175656 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,11668188 0,14166318 ! negative regulation of immune system process GO:0002683 25 25 0,000 0,11668188 0,14156992 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,11668188 0,14147678 ! positive regulation of defense response GO:0031349 26 26 0,000 0,12106303 0,14669242 ! glycolysis GO:0006096 26 26 0,000 0,12106303 0,14659604 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,12106303 0,14649978 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,12106303 0,14640366 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,12106303 0,14630765 ! induction of apoptosis by intracellular signals GO:0008629 26 26 0,000 0,12106303 0,14621178 ! cellular defense response GO:0006968 26 26 0,000 0,12106303 0,14611603 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,12106303 0,1460204 ! regulation of T cell differentiation GO:0045580 26 26 0,000 0,12106303 0,1459249 ! double-strand break repair GO:0006302 27 26 0,000 0,12106303 0,14582952 ! regulation of protein secretion GO:0050708 26 26 0,000 0,12106303 0,14573427 ! germ cell development GO:0007281 27 26 0,000 0,12106303 0,14563915 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,12106303 0,14554414 GO:0035150|regulation of tube size, ! maintenance of location in cell GO:0051651 27 26 0,000 0,12106303 0,14544926 ! synapse organization GO:0050808 26 26 0,000 0,12106303 0,14535451 ! chloride transport GO:0006821 27 27 0,000 0,1254231 0,15049138 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,1254231 0,15039347 ! energy reserve metabolic process GO:0006112 28 27 0,000 0,1254231 0,15029569 ! learning or memory GO:0007611 28 27 0,000 0,1254231 0,15019803 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,1254231 0,1501005 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,1254231 0,15000309 ! peptide metabolic process GO:0006518 29 27 0,000 0,1254231 0,14990581 ! activation of caspase activity GO:0006919 27 27 0,000 0,1254231 0,14980866 ! mesenchymal cell development GO:0014031 29 27 0,000 0,1254231 0,14971164 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! inner ear development GO:0048839 27 27 0,000 0,1254231 0,14961473 ! defense response to bacterium GO:0042742 27 27 0,000 0,1254231 0,14951796 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,1254231 0,14942131 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,1254231 0,14932478 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,12976216 0,154391 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,12976216 0,15429139 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,12976216 0,15419192 ! carbohydrate transport GO:0008643 28 28 0,000 0,12976216 0,15409257 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,12976216 0,15399334 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,12976216 0,15389425 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,12976216 0,15379528 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,12976216 0,15369644 ! developmental growth GO:0048589 28 28 0,000 0,12976216 0,15359773 ! regulation of mast cell proliferation GO:0070666 28 28 0,000 0,12976216 0,15349914 ! cartilage development GO:0051216 29 28 0,000 0,12976216 0,15340068 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,13408033 0,15840388 ! leukocyte migration GO:0050900 30 29 0,000 0,13408033 0,1583024 ! branching morphogenesis of a tube GO:0048754 29 29 0,000 0,13408033 0,15820105 ! regulation of lymphocyte proliferation GO:0050670 29 29 0,000 0,13408033 0,15809984 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,13408033 0,15799875 ! tRNA processing GO:0008033 29 29 0,000 0,13408033 0,15789779 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,13408033 0,15779696 ! adult behavior GO:0030534 30 29 0,000 0,13408033 0,15769626 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,13408033 0,15759569 ! positive regulation of protein transport GO:0051222 29 29 0,000 0,13408033 0,15749525 ! transition metal ion transport GO:0000041 31 30 0,000 0,1383777 0,16243955 ! RNA catabolic process GO:0006401 30 30 0,000 0,1383777 0,16233615 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,1383777 0,16223288 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,1383777 0,16212975 ! positive regulation of peptidase activity GO:0010952 30 30 0,000 0,1383777 0,16202674 GO:0043280|positive regulation of caspase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,1383777 0,16192387 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,1383777 0,16182113 ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,1383777 0,16171851 ! positive regulation of response to external stimulus GO:0032103 30 30 0,000 0,1383777 0,16161603 ! skeletal system morphogenesis GO:0048705 31 30 0,000 0,1383777 0,16151368 ! vascular process in circulatory system GO:0003018 31 30 0,000 0,1383777 0,16141145 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,1383777 0,16130936 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,1383777 0,16120739 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,1383777 0,16110556 ! vesicle organization GO:0016050 30 30 0,000 0,1383777 0,16100385 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,1383777 0,16090227 ! skeletal muscle fiber development GO:0048741 31 31 0,000 0,14265436 0,16577048 ! membrane fusion GO:0006944 31 31 0,000 0,14265436 0,16566603 ! B cell activation GO:0042113 31 31 0,000 0,14265436 0,16556171 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,14265436 0,16545751 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,14265436 0,16535345 ! ion transmembrane transport GO:0034220 31 31 0,000 0,14265436 0,16524952 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,14265436 0,16514572 ! digestion GO:0007586 31 31 0,000 0,14265436 0,16504205 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,14265436 0,16493851 ! regulation of heart contraction GO:0008016 31 31 0,000 0,14265436 0,1648351 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,14265436 0,16473182 ! camera-type eye development GO:0043010 31 31 0,000 0,14265436 0,16462867 ! extracellular matrix organization GO:0030198 31 31 0,000 0,14265436 0,16452565 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,14265436 0,16442276 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,14265436 0,16431999 ! negative regulation of cell growth GO:0030308 32 32 0,000 0,14691042 0,16911674 ! cell redox homeostasis GO:0045454 32 32 0,000 0,14691042 0,16901118 ! muscle fiber development GO:0048747 32 32 0,000 0,14691042 0,16890574 ! glucose catabolic process GO:0006007 32 32 0,000 0,14691042 0,16880044 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,14691042 0,16869527 ! cell maturation GO:0048469 32 32 0,000 0,14691042 0,16859023 ! morphogenesis of a branching structure GO:0001763 32 32 0,000 0,14691042 0,16848532 ! regulation of lymphocyte differentiation GO:0045619 32 32 0,000 0,14691042 0,16838054 ! kidney development GO:0001822 32 32 0,000 0,14691042 0,16827589 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,14691042 0,16817137 ! negative regulation of cell size GO:0045792 33 33 0,000 0,15114597 0,17291249 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,15114597 0,17280523 ! amino acid transport GO:0006865 33 33 0,000 0,15114597 0,17269809 ! activation of protein kinase activity GO:0032147 35 33 0,000 0,15114597 0,17259109 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,15114597 0,17248423 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,15114597 0,17237749 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,15114597 0,17227089 ! regulation of actin filament length GO:0030832 34 34 0,000 0,15536111 0,17696571 ! ear development GO:0043583 34 34 0,000 0,15536111 0,17685641 ! cellular polysaccharide metabolic process GO:0044264 35 34 0,000 0,15536111 0,17674724 ! regulation of protein catabolic process GO:0042176 35 34 0,000 0,15536111 0,1766382 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,15536111 0,1765293 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,15536111 0,17642053 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,15536111 0,1763119 ! detection of stimulus GO:0051606 36 34 0,000 0,15536111 0,1762034 ! acute inflammatory response GO:0002526 35 35 0,000 0,15955593 0,18084967 ! regulation of cellular component size GO:0032535 35 35 0,000 0,15955593 0,18073852 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,15955593 0,1806275 ! mesoderm development GO:0007498 35 35 0,000 0,15955593 0,18051662 ! regulation of cell morphogenesis GO:0022604 38 35 0,000 0,15955593 0,18040587 ! inorganic anion transport GO:0015698 35 35 0,000 0,15955593 0,18029526 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,15955593 0,18018479 ! regulation of immune effector process GO:0002697 35 35 0,000 0,15955593 0,18007445 ! hydrogen transport GO:0006818 36 36 0,000 0,16373052 0,1846728 GO:0015992|proton transport, ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,16373052 0,18455985 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,16373052 0,18444703 ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,16373052 0,18433436 GO:0035113|embryonic appendage morphogenesis, ! female pregnancy GO:0007565 37 36 0,000 0,16373052 0,18422182 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,16373052 0,18410943 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,16373052 0,18399716 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,16373052 0,18388504 ! gonad development GO:0008406 36 36 0,000 0,16373052 0,18377305 ! activation of immune response GO:0002253 36 36 0,000 0,16373052 0,1836612 ! coagulation GO:0050817 39 36 0,000 0,16373052 0,18354948 GO:0007596|blood coagulation, ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,16788499 0,18809242 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! response to drug GO:0042493 37 37 0,000 0,16788499 0,18797815 ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,16788499 0,18786401 ! eye development GO:0001654 37 37 0,000 0,16788499 0,18775002 ! negative regulation of growth GO:0045926 37 37 0,000 0,16788499 0,18763616 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,16788499 0,18752244 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,16788499 0,18740886 ! adaptive immune response GO:0002250 37 37 0,000 0,16788499 0,18729542 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! neurotransmitter transport GO:0006836 40 38 0,000 0,17201942 0,19179176 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,17201942 0,19167581 ! exocytosis GO:0006887 40 38 0,000 0,17201942 0,19155999 ! hexose catabolic process GO:0019320 38 38 0,000 0,17201942 0,19144431 ! RNA elongation GO:0006354 38 38 0,000 0,17201942 0,19132878 ! axon guidance GO:0007411 39 38 0,000 0,17201942 0,19121338 ! regulation of neurological system process GO:0031644 38 38 0,000 0,17201942 0,19109812 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,17613391 0,19555108 ! hemostasis GO:0007599 42 39 0,000 0,17613391 0,19543335 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,17613391 0,19531576 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,17613391 0,19519831 ! nucleotide-excision repair GO:0006289 40 39 0,000 0,17613391 0,195081 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,17613391 0,19496384 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,17613391 0,19484681 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,17613391 0,19472993 ! developmental maturation GO:0021700 39 39 0,000 0,17613391 0,19461318 ! lymphocyte differentiation GO:0030098 39 39 0,000 0,17613391 0,19449658 ! limb development GO:0060173 39 39 0,000 0,17613391 0,19438011 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,18022855 0,1987799 ! DNA catabolic process GO:0006308 41 40 0,000 0,18022855 0,19866101 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,18430344 0,20303122 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! amine catabolic process GO:0009310 42 41 0,000 0,18430344 0,20290994 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,18430344 0,2027888 ! regulation of caspase activity GO:0043281 41 41 0,000 0,18430344 0,2026678 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,18430344 0,20254695 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,18430344 0,20242624 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,18430344 0,20230568 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,18430344 0,20218526 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,18835866 0,20651101 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,18835866 0,20638823 ! regulation of endopeptidase activity GO:0052548 42 42 0,000 0,18835866 0,2062656 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,18835866 0,20614312 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,18835866 0,20602078 ! protein ubiquitination GO:0016567 43 42 0,000 0,18835866 0,20589858 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,18835866 0,20577653 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! forebrain development GO:0030900 43 42 0,000 0,18835866 0,20565463 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,18835866 0,20553287 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 0,000 0,18835866 0,20541125 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,19239431 0,20968819 ! mitochondrion organization GO:0007005 44 43 0,000 0,19239431 0,20956426 ! alcohol catabolic process GO:0046164 43 43 0,000 0,19239431 0,20944047 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,19239431 0,20931684 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,19239431 0,20919335 ! humoral immune response GO:0006959 44 44 0,000 0,19641049 0,21343428 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 0,000 0,19641049 0,21330851 ! mRNA transport GO:0051028 44 44 0,000 0,19641049 0,21318288 ! protein import into nucleus GO:0006606 44 44 0,000 0,19641049 0,21305741 ! negative regulation of organelle organization GO:0010639 45 44 0,000 0,19641049 0,21293208 ! vitamin metabolic process GO:0006766 44 44 0,000 0,19641049 0,2128069 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,19641049 0,21268187 ! amine biosynthetic process GO:0009309 46 45 0,000 0,20040728 0,21688233 ! homophilic cell adhesion GO:0007156 45 45 0,000 0,20040728 0,21675506 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,20040728 0,21662793 ! phosphoinositide-mediated signaling GO:0048015 45 45 0,000 0,20040728 0,21650095 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 0,000 0,20040728 0,21637412 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,20040728 0,21624743 ! nuclear import GO:0051170 45 45 0,000 0,20040728 0,2161209 ! Wnt receptor signaling pathway GO:0016055 46 45 0,000 0,20040728 0,21599451 ! protein processing GO:0016485 45 45 0,000 0,20040728 0,21586827 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,20438477 0,22002403 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,20438477 0,21989558 ! tube morphogenesis GO:0035239 47 46 0,000 0,20438477 0,21976729 ! regulation of peptidase activity GO:0052547 46 46 0,000 0,20438477 0,21963914 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 0,000 0,20438477 0,21951115 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,20438477 0,2193833 ! positive regulation of ligase activity GO:0051351 47 46 0,000 0,20438477 0,21925561 ! regulation of membrane potential GO:0042391 46 46 0,000 0,20438477 0,21912806 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,20834305 0,22324201 ! regulation of blood pressure GO:0008217 48 47 0,000 0,20834305 0,22311229 ! amine transport GO:0015837 47 47 0,000 0,20834305 0,22298272 ! rhythmic process GO:0048511 47 47 0,000 0,20834305 0,22285331 ! calcium ion transport GO:0006816 48 48 0,000 0,21228222 0,22693511 ! actin filament organization GO:0007015 50 48 0,000 0,21228222 0,22680356 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 0,000 0,21228222 0,22667215 ! protein localization in nucleus GO:0034504 48 48 0,000 0,21228222 0,2265409 ! DNA recombination GO:0006310 48 48 0,000 0,21228222 0,2264098 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,21620236 0,23045746 ! divalent metal ion transport GO:0070838 49 49 0,000 0,21620236 0,23032425 ! response to nutrient GO:0007584 49 49 0,000 0,21620236 0,23019119 ! response to bacterium GO:0009617 50 49 0,000 0,21620236 0,23005829 ! regulation of ligase activity GO:0051340 50 49 0,000 0,21620236 0,22992554 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,21620236 0,22979294 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,21620236 0,22966049 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,22010357 0,23366986 ! chromatin assembly GO:0031497 50 50 0,000 0,22010357 0,23353533 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,22010357 0,23340096 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! T cell activation GO:0042110 51 50 0,000 0,22010357 0,23326675 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 0,000 0,22010357 0,23313269 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,22010357 0,23299878 ! transcription initiation GO:0006352 50 50 0,000 0,22010357 0,23286503 ! anatomical structure homeostasis GO:0060249 51 50 0,000 0,22010357 0,23273143 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,22398592 0,23670072 ! protein modification by small protein conjugation GO:0032446 52 51 0,000 0,22398592 0,23656507 ! positive regulation of immune response GO:0050778 51 51 0,000 0,22398592 0,23642958 ! rRNA metabolic process GO:0016072 51 51 0,000 0,22398592 0,23629425 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,22398592 0,23615907 ! ATP biosynthetic process GO:0006754 51 51 0,000 0,22398592 0,23602404 ! RNA localization GO:0006403 52 52 0,000 0,22784951 0,23995809 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,22784951 0,23982105 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 0,000 0,22784951 0,23968416 ! cell fate commitment GO:0045165 52 52 0,000 0,22784951 0,23954744 ! regulation of body fluid levels GO:0050878 55 52 0,000 0,22784951 0,23941086 ! sodium ion transport GO:0006814 53 53 0,000 0,23169444 0,24331216 ! tRNA metabolic process GO:0006399 53 53 0,000 0,23169444 0,2431736 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,23169444 0,2430352 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,23169444 0,24289695 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,23169444 0,24275887 ! regulation of T cell activation GO:0050863 53 53 0,000 0,23169444 0,24262093 ! sulfur metabolic process GO:0006790 55 54 0,000 0,23552077 0,24648767 ! negative regulation of multicellular organismal process GO:0051241 55 54 0,000 0,23552077 0,24634777 ! nucleosome organization GO:0034728 55 55 0,000 0,23932861 0,25018867 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,23932861 0,25004684 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! in utero embryonic development GO:0001701 55 55 0,000 0,23932861 0,24990517 ! protein modification by small protein conjugation or removal GO:0070647 56 55 0,000 0,23932861 0,24976366 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,24311803 0,25357472 ! extracellular structure organization GO:0043062 56 56 0,000 0,24311803 0,2534313 ! ATP metabolic process GO:0046034 57 57 0,000 0,24688913 0,25721689 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,24688913 0,25707157 ! innate immune response GO:0045087 58 58 0,000 0,25064199 0,26083184 ! carboxylic acid transport GO:0046942 59 59 0,000 0,2543767 0,26456899 GO:0015849|organic acid transport, ! sterol metabolic process GO:0016125 59 59 0,000 0,2543767 0,26441977 ! protein localization in organelle GO:0033365 59 59 0,000 0,2543767 0,26427072 ! immune effector process GO:0002252 59 59 0,000 0,2543767 0,26412184 ! protein polymerization GO:0051258 65 60 0,000 0,25809334 0,26782997 ! cellular respiration GO:0045333 62 61 0,000 0,26179199 0,27151528 ! proteasomal protein catabolic process GO:0010498 62 61 0,000 0,26179199 0,27136257 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,26179199 0,27121003 GO:0016054|organic acid catabolic process, ! lipid transport GO:0006869 62 62 0,000 0,26547275 0,2748687 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,26547275 0,27471436 ! morphogenesis of an epithelium GO:0002009 63 62 0,000 0,26547275 0,2745602 GO:0060429|epithelium development, ! protein import GO:0017038 62 62 0,000 0,26547275 0,27440621 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,26547275 0,2742524 ! regulation of lymphocyte activation GO:0051249 62 62 0,000 0,26547275 0,27409875 ! glucose metabolic process GO:0006006 63 63 0,000 0,26913569 0,27772513 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,26913569 0,27756971 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,26913569 0,27741447 ! regulation of response to external stimulus GO:0032101 65 64 0,000 0,2727809 0,28101464 ! regulation of cytoskeleton organization GO:0051493 66 64 0,000 0,2727809 0,28085765 ! anion transport GO:0006820 65 65 0,000 0,27640846 0,28443372 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,28001845 0,28798773 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,28001845 0,28782711 ! DNA packaging GO:0006323 66 66 0,000 0,28001845 0,28766667 ! polysaccharide metabolic process GO:0005976 69 66 0,000 0,28001845 0,28750641 ! Golgi vesicle transport GO:0048193 67 67 0,000 0,28361096 0,29103285 ! muscle contraction GO:0006936 67 67 0,000 0,28361096 0,2908709 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,28718607 0,29437371 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,28718607 0,29421008 ! response to nutrient levels GO:0031667 69 69 0,000 0,29074387 0,29768941 ! regulation of leukocyte activation GO:0002694 69 69 0,000 0,29074387 0,29752412 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,29428442 0,30098012 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,29780782 0,30441476 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,29780782 0,30424601 ! ribosome biogenesis GO:0042254 71 71 0,000 0,29780782 0,30407745 ! regulation of cell activation GO:0050865 71 71 0,000 0,29780782 0,30390908 ! secretion by cell GO:0032940 75 72 0,000 0,30131414 0,30731707 ! muscle system process GO:0003012 72 72 0,000 0,30131414 0,3071471 ! sensory organ development GO:0007423 72 72 0,000 0,30131414 0,30697731 ! response to extracellular stimulus GO:0009991 72 72 0,000 0,30131414 0,30680771 ! regulation of cytokine production GO:0001817 72 72 0,000 0,30131414 0,30663829 ! electron transport chain GO:0022900 75 74 0,000 0,30827587 0,3135499 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,30827587 0,31337696 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,31173144 0,31671502 ! response to oxidative stress GO:0006979 76 75 0,000 0,31173144 0,31654052 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,31173144 0,31636621 ! positive regulation of multicellular organismal process GO:0051240 76 76 0,000 0,31517025 0,31968012 ! microtubule-based movement GO:0007018 82 78 0,000 0,32199793 0,32642584 ! regulation of immune response GO:0050776 78 78 0,000 0,32199793 0,32624639 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,32875951 0,33291416 ! lymphocyte activation GO:0046649 82 81 0,000 0,33211571 0,33612809 ! lipid catabolic process GO:0016042 82 81 0,000 0,33211571 0,33594361 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,33877932 0,34249605 ! ncRNA processing GO:0034470 83 83 0,000 0,33877932 0,34230827 ! cellular amino acid derivative metabolic process GO:0006575 87 84 0,000 0,34208689 0,34546089 ! nitrogen compound biosynthetic process GO:0044271 86 85 0,000 0,34537839 0,34859385 ! positive regulation of response to stimulus GO:0048584 86 85 0,000 0,34537839 0,34840305 ! hexose metabolic process GO:0019318 87 86 0,000 0,3486539 0,35151485 ! male gamete generation GO:0048232 90 88 0,000 0,35515728 0,35787582 GO:0007283|spermatogenesis, ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,35515728 0,35768026 ! chemotaxis GO:0006935 90 89 0,000 0,35838529 0,36073408 GO:0042330|taxis, ! brain development GO:0007420 91 90 0,000 0,36159762 0,36376878 ! visual perception GO:0007601 93 92 0,000 0,36797551 0,36998301 GO:0050953|sensory perception of light stimulus, ! fatty acid metabolic process GO:0006631 93 92 0,000 0,36797551 0,36978127 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 0,000 0,36797551 0,36957976 ! positive regulation of immune system process GO:0002684 92 92 0,000 0,36797551 0,36937846 ! tissue morphogenesis GO:0048729 94 93 0,000 0,37114121 0,37235343 ! regulation of response to stress GO:0080134 97 94 0,000 0,37429153 0,37530973 ! cofactor metabolic process GO:0051186 95 94 0,000 0,37429153 0,37510565 ! endocytosis GO:0006897 99 98 0,000 0,38674032 0,38737087 GO:0010324|membrane invagination, ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,38674032 0,38716046 ! blood circulation GO:0008015 99 98 0,000 0,38674032 0,38695028 GO:0003013|circulatory system process, ! regulation of system process GO:0044057 98 98 0,000 0,38674032 0,38674032