Study Desmedt-ER-neg
Study informations
165 subnetworks in total page | file
2310 genes associated page | file
Enriched GO terms page
General informations
General Index page
Study Index page
Subnetwork 6070
score
| Dataset | Score | P-val 1 | P-val 2 | P-val 3 | Fisher Score |
|---|
| IPC | 0.7618 | 3.045e-03 | 4.760e-04 | 7.488e-01 | 1.085e-06 |
|---|
| Loi | 0.2239 | 9.052e-02 | 1.422e-02 | 4.525e-01 | 5.824e-04 |
|---|
| Schmidt | 0.6744 | 0.000e+00 | 0.000e+00 | 4.383e-02 | 0.000e+00 |
|---|
| VanDeVijver | 0.7899 | 0.000e+00 | 0.000e+00 | 3.583e-03 | 0.000e+00 |
|---|
| Wang | 0.2590 | 3.049e-03 | 4.710e-02 | 4.113e-01 | 5.906e-05 |
|---|
Expression data for subnetwork 6070 in each dataset
IPC |
Loi |
Schmidt |
VanDeVijver |
Wang |
Subnetwork structure for each dataset
- IPC
Score for each gene in subnetwork 6070 in each dataset
| Gene Symbol | Links | Frequency | Frequency Rank | Subnetwork score rank | Global rank |
IPC | Loi | Schmidt | VanDeVijver | Wang |
|---|
| EP300 |   | 113 | 4 | 1 | 4 | -0.149 | 0.087 | 0.102 | 0.052 | 0.025 |
|---|
| CDC42EP3 | | 2 | 743 | 2284 | 2253 | -0.159 | 0.338 | -0.073 | undef | 0.220 |
|---|
| TFF3 | | 2 | 743 | 1396 | 1391 | 0.029 | 0.070 | -0.026 | 0.098 | -0.093 |
|---|
| NF1 | | 9 | 196 | 552 | 541 | 0.110 | -0.052 | -0.032 | 0.090 | -0.094 |
|---|
| SIX6 | | 2 | 743 | 727 | 734 | undef | -0.032 | 0.000 | 0.106 | 0.153 |
|---|
| JDP2 | | 4 | 440 | 2053 | 2008 | 0.062 | 0.045 | undef | undef | undef |
|---|
| EYA1 | | 8 | 222 | 1010 | 981 | 0.135 | -0.065 | 0.162 | 0.068 | -0.088 |
|---|
| TRAF2 | | 3 | 557 | 658 | 654 | 0.185 | -0.172 | -0.013 | undef | -0.092 |
|---|
| EGF | | 12 | 140 | 638 | 620 | -0.212 | 0.182 | -0.276 | -0.060 | 0.005 |
|---|
| CDC42SE1 | | 1 | 1195 | 2307 | 2307 | 0.220 | -0.105 | -0.050 | 0.139 | -0.148 |
|---|
| FOXA3 | | 12 | 140 | 318 | 322 | 0.192 | 0.289 | undef | -0.171 | undef |
|---|
| TP53 | | 85 | 7 | 1 | 6 | -0.167 | 0.148 | -0.027 | 0.252 | 0.147 |
|---|
| ERBB2 | | 141 | 1 | 1 | 1 | -0.103 | 0.092 | -0.090 | 0.267 | 0.046 |
|---|
| CHEK1 | | 18 | 86 | 141 | 136 | 0.189 | -0.134 | 0.119 | -0.088 | -0.054 |
|---|
| ID4 | | 35 | 34 | 236 | 223 | -0.179 | 0.137 | 0.241 | undef | 0.036 |
|---|
| HNRNPH1 | | 9 | 196 | 614 | 597 | -0.059 | 0.248 | 0.125 | 0.144 | -0.133 |
|---|
| CDKN1A | | 110 | 5 | 1 | 5 | 0.064 | 0.254 | 0.030 | undef | 0.082 |
|---|
| ERBB4 | | 3 | 557 | 1294 | 1276 | 0.078 | 0.008 | 0.029 | -0.063 | -0.053 |
|---|
| SIX4 | | 2 | 743 | 1893 | 1869 | 0.135 | -0.094 | undef | -0.001 | undef |
|---|
| RB1 | | 31 | 43 | 1 | 22 | 0.013 | -0.051 | 0.057 | 0.100 | -0.082 |
|---|
| SIX1 | | 2 | 743 | 727 | 734 | 0.133 | -0.134 | 0.005 | -0.084 | 0.068 |
|---|
| CDC42 | | 26 | 52 | 179 | 177 | 0.047 | 0.242 | -0.027 | 0.040 | -0.042 |
|---|
| CTGF | | 32 | 40 | 318 | 290 | -0.169 | 0.181 | 0.126 | 0.101 | 0.209 |
|---|
| PLAU | | 12 | 140 | 179 | 192 | 0.187 | 0.153 | 0.141 | 0.072 | 0.192 |
|---|
| PTEN | | 27 | 50 | 141 | 135 | 0.045 | 0.055 | 0.017 | 0.183 | -0.041 |
|---|
| GATA2 | | 1 | 1195 | 2307 | 2307 | 0.055 | 0.114 | -0.027 | undef | -0.063 |
|---|
| GNAZ | | 15 | 111 | 478 | 457 | 0.134 | -0.116 | 0.308 | 0.267 | 0.011 |
|---|
| GPRIN2 | | 16 | 104 | 179 | 190 | 0.084 | 0.078 | 0.012 | 0.054 | 0.114 |
|---|
| GMPS | | 7 | 256 | 318 | 328 | 0.083 | -0.022 | 0.044 | -0.019 | 0.151 |
|---|
| ERBB3 | | 3 | 557 | 1922 | 1888 | -0.171 | -0.007 | -0.141 | -0.019 | -0.098 |
|---|
| DLX4 | | 10 | 167 | 236 | 234 | 0.291 | 0.057 | -0.004 | undef | -0.059 |
|---|
| SPRY2 | | 1 | 1195 | 2307 | 2307 | -0.215 | 0.014 | 0.151 | -0.014 | -0.095 |
|---|
| CPSF6 | | 6 | 301 | 318 | 330 | 0.164 | 0.052 | 0.091 | 0.129 | -0.088 |
|---|
| SP1 | | 72 | 10 | 83 | 77 | 0.222 | -0.254 | 0.239 | 0.020 | 0.082 |
|---|
| MDFI | | 17 | 95 | 236 | 226 | -0.075 | -0.001 | 0.177 | 0.169 | -0.112 |
|---|
| AKT1 | | 16 | 104 | 236 | 227 | 0.045 | 0.126 | -0.099 | undef | -0.168 |
|---|
| PARP1 | | 29 | 45 | 83 | 84 | -0.036 | -0.162 | -0.089 | 0.238 | 0.012 |
|---|
| PIK3R1 | | 127 | 2 | 1 | 2 | -0.237 | 0.381 | 0.065 | undef | -0.002 |
|---|
| DLX3 | | 3 | 557 | 236 | 265 | 0.144 | -0.056 | undef | -0.015 | undef |
|---|
| EYA3 | | 9 | 196 | 318 | 324 | -0.034 | 0.053 | -0.020 | 0.188 | -0.142 |
|---|
| ACTN1 | | 18 | 86 | 318 | 313 | 0.016 | 0.347 | 0.068 | 0.100 | 0.314 |
|---|
| CDC42BPA | | 6 | 301 | 1268 | 1236 | -0.102 | 0.098 | 0.059 | 0.368 | 0.260 |
|---|
| PPFIA3 | | 2 | 743 | 2053 | 2031 | -0.037 | -0.042 | -0.144 | undef | 0.014 |
|---|
| FLNA | | 50 | 20 | 1 | 14 | 0.081 | 0.107 | 0.148 | 0.268 | 0.126 |
|---|
| RASA1 | | 2 | 743 | 1358 | 1360 | -0.079 | 0.146 | 0.127 | -0.056 | 0.149 |
|---|
| BAIAP2 | | 3 | 557 | 412 | 430 | -0.077 | -0.025 | 0.099 | 0.092 | -0.051 |
|---|
| EGFR | | 117 | 3 | 1 | 3 | -0.195 | 0.240 | -0.205 | -0.187 | 0.065 |
|---|
| TRIB3 | | 1 | 1195 | 2307 | 2307 | 0.119 | 0.133 | -0.046 | undef | 0.093 |
|---|
| INSR | | 96 | 6 | 236 | 221 | 0.063 | 0.173 | 0.135 | -0.014 | -0.072 |
|---|
| MST1R | | 5 | 360 | 236 | 242 | 0.124 | 0.083 | -0.212 | -0.001 | 0.026 |
|---|
| AKT3 | | 5 | 360 | 1083 | 1066 | 0.172 | -0.058 | 0.087 | 0.121 | 0.080 |
|---|
| GRB7 | | 58 | 18 | 1 | 12 | 0.021 | 0.115 | -0.072 | 0.229 | 0.129 |
|---|
| ROD1 | | 4 | 440 | 1564 | 1542 | 0.049 | 0.088 | 0.052 | 0.011 | -0.223 |
|---|
| KLF5 | | 76 | 9 | 1 | 7 | 0.077 | 0.117 | -0.007 | -0.110 | -0.006 |
|---|
| ITGB4 | | 35 | 34 | 1 | 20 | 0.021 | 0.313 | -0.134 | 0.080 | -0.114 |
|---|
| PDLIM5 | | 4 | 440 | 318 | 337 | -0.091 | 0.242 | -0.085 | -0.001 | 0.117 |
|---|
| EYA2 | | 13 | 124 | 318 | 316 | -0.034 | 0.113 | -0.142 | undef | -0.019 |
|---|
| CDKN2A | | 60 | 17 | 1 | 11 | 0.263 | -0.113 | 0.111 | undef | -0.105 |
|---|
| FGD1 | | 2 | 743 | 1274 | 1260 | 0.008 | -0.131 | -0.053 | 0.043 | -0.074 |
|---|
GO Enrichment output for subnetwork 6070 in each dataset
| Name | Accession Number | Link | P-val | Corrected P-val |
|---|
| regulation of cyclin-dependent protein kinase activity | GO:0000079 |  | 1.514E-13 | 3.698E-10 |
|---|
| negative regulation of cell-matrix adhesion | GO:0001953 | | 4.617E-12 | 5.64E-09 |
|---|
| regulation of cell-matrix adhesion | GO:0001952 | | 1.069E-11 | 8.704E-09 |
|---|
| negative regulation of cell adhesion | GO:0007162 | | 4.246E-10 | 2.593E-07 |
|---|
| regulation of cell adhesion | GO:0030155 | | 5.891E-10 | 2.878E-07 |
|---|
| interphase of mitotic cell cycle | GO:0051329 | | 1.042E-09 | 4.241E-07 |
|---|
| G1/S transition of mitotic cell cycle | GO:0000082 | | 2.13E-09 | 7.434E-07 |
|---|
| phospholipid dephosphorylation | GO:0046839 | | 2.399E-09 | 7.325E-07 |
|---|
| muscle cell migration | GO:0014812 | | 2.399E-09 | 6.511E-07 |
|---|
| nuclear migration | GO:0007097 | | 7.17E-09 | 1.752E-06 |
|---|
| negative regulation of protein kinase B signaling cascade | GO:0051898 | | 7.17E-09 | 1.592E-06 |
|---|
| Name | Accession Number | Link | P-val | Corrected P-val |
|---|
| regulation of cyclin-dependent protein kinase activity | GO:0000079 | | 3.881E-13 | 9.339E-10 |
|---|
| negative regulation of cell-matrix adhesion | GO:0001953 | | 8.242E-12 | 9.915E-09 |
|---|
| regulation of cell-matrix adhesion | GO:0001952 | | 2.09E-11 | 1.676E-08 |
|---|
| negative regulation of cell adhesion | GO:0007162 | | 5.44E-10 | 3.272E-07 |
|---|
| regulation of cell adhesion | GO:0030155 | | 1.005E-09 | 4.836E-07 |
|---|
| interphase of mitotic cell cycle | GO:0051329 | | 1.809E-09 | 7.254E-07 |
|---|
| interphase | GO:0051325 | | 2.391E-09 | 8.217E-07 |
|---|
| phospholipid dephosphorylation | GO:0046839 | | 3.539E-09 | 1.064E-06 |
|---|
| muscle cell migration | GO:0014812 | | 3.539E-09 | 9.462E-07 |
|---|
| G1/S transition of mitotic cell cycle | GO:0000082 | | 4.127E-09 | 9.929E-07 |
|---|
| nuclear migration | GO:0007097 | | 1.057E-08 | 2.313E-06 |
|---|
| Name | Accession Number | Link | P-val | Corrected P-val |
|---|
| regulation of cyclin-dependent protein kinase activity | GO:0000079 | | 1.694E-09 | 3.897E-06 |
|---|
| negative regulation of cell-matrix adhesion | GO:0001953 | | 3.156E-09 | 3.629E-06 |
|---|
| regulation of cell-matrix adhesion | GO:0001952 | | 5.683E-09 | 4.357E-06 |
|---|
| filopodium assembly | GO:0046847 | | 5.754E-09 | 3.309E-06 |
|---|
| nuclear migration | GO:0007097 | | 9.811E-09 | 4.513E-06 |
|---|
| microspike assembly | GO:0030035 | | 9.811E-09 | 3.761E-06 |
|---|
| G1/S transition of mitotic cell cycle | GO:0000082 | | 1.406E-08 | 4.619E-06 |
|---|
| regulation of lipid kinase activity | GO:0043550 | | 6.796E-08 | 1.954E-05 |
|---|
| establishment of nucleus localization | GO:0040023 | | 6.796E-08 | 1.737E-05 |
|---|
| negative regulation of cell adhesion | GO:0007162 | | 7.941E-08 | 1.826E-05 |
|---|
| regulation of cell adhesion | GO:0030155 | | 8.771E-08 | 1.834E-05 |
|---|
VanDeVijver file
| Name | Accession Number | Link | P-val | Corrected P-val |
|---|
| filopodium assembly | GO:0046847 | | 6.585E-09 | 1.214E-05 |
|---|
| muscle cell migration | GO:0014812 | | 6.585E-09 | 6.068E-06 |
|---|
| muscle tissue development | GO:0060537 | | 8.327E-09 | 5.116E-06 |
|---|
| heart development | GO:0007507 | | 4.77E-08 | 2.198E-05 |
|---|
| regulation of MAP kinase activity | GO:0043405 | | 1.325E-07 | 4.885E-05 |
|---|
| muscle organ development | GO:0007517 | | 1.432E-07 | 4.397E-05 |
|---|
| striated muscle tissue development | GO:0014706 | | 1.473E-07 | 3.879E-05 |
|---|
| cell projection assembly | GO:0030031 | | 2.324E-07 | 5.353E-05 |
|---|
| regulation of anatomical structure morphogenesis | GO:0022603 | | 8.339E-07 | 1.708E-04 |
|---|
| regulation of cell-substrate adhesion | GO:0010810 | | 9.081E-07 | 1.674E-04 |
|---|
| regulation of cell adhesion | GO:0030155 | | 9.585E-07 | 1.606E-04 |
|---|
| Name | Accession Number | Link | P-val | Corrected P-val |
|---|
| regulation of cyclin-dependent protein kinase activity | GO:0000079 | | 1.694E-09 | 3.897E-06 |
|---|
| negative regulation of cell-matrix adhesion | GO:0001953 | | 3.156E-09 | 3.629E-06 |
|---|
| regulation of cell-matrix adhesion | GO:0001952 | | 5.683E-09 | 4.357E-06 |
|---|
| filopodium assembly | GO:0046847 | | 5.754E-09 | 3.309E-06 |
|---|
| nuclear migration | GO:0007097 | | 9.811E-09 | 4.513E-06 |
|---|
| microspike assembly | GO:0030035 | | 9.811E-09 | 3.761E-06 |
|---|
| G1/S transition of mitotic cell cycle | GO:0000082 | | 1.406E-08 | 4.619E-06 |
|---|
| regulation of lipid kinase activity | GO:0043550 | | 6.796E-08 | 1.954E-05 |
|---|
| establishment of nucleus localization | GO:0040023 | | 6.796E-08 | 1.737E-05 |
|---|
| negative regulation of cell adhesion | GO:0007162 | | 7.941E-08 | 1.826E-05 |
|---|
| regulation of cell adhesion | GO:0030155 | | 8.771E-08 | 1.834E-05 |
|---|
