pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6070-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 9,000 3,881E-13 9,339E-10 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 5,000 8,242E-12 9,915E-09 GO:0010812|negative regulation of cell-substrate adhesion, ! regulation of cell-matrix adhesion GO:0001952 78 23 6,000 2,09E-11 1,676E-08 GO:0010810|regulation of cell-substrate adhesion, ! negative regulation of cell adhesion GO:0007162 81 35 6,000 5,44E-10 3,272E-07 ! regulation of cell adhesion GO:0030155 212 89 8,000 1,005E-09 4,836E-07 ! interphase of mitotic cell cycle GO:0051329 209 95 8,000 1,809E-09 7,254E-07 ! interphase GO:0051325 213 98 8,000 2,391E-09 8,217E-07 ! phospholipid dephosphorylation GO:0046839 12 5 3,000 3,539E-09 1,064E-06 ! muscle cell migration GO:0014812 8 5 3,000 3,539E-09 9,462E-07 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 6,000 4,127E-09 9,929E-07 ! nuclear migration GO:0007097 12 6 3,000 1,057E-08 2,313E-06 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 3,000 1,057E-08 2,12E-06 ! filopodium assembly GO:0046847 32 16 4,000 1,506E-08 2,787E-06 ! microspike assembly GO:0030035 36 17 4,000 2,124E-08 3,651E-06 ! regulation of lipid kinase activity GO:0043550 13 7 3,000 2,457E-08 3,942E-06 ! negative regulation of focal adhesion formation GO:0051895 20 7 3,000 2,457E-08 3,695E-06 ! regulation of protein stability GO:0031647 73 37 5,000 3,709E-08 5,249E-06 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 3,000 4,895E-08 6,543E-06 ! regulation of focal adhesion formation GO:0051893 22 8 3,000 4,895E-08 6,198E-06 ! establishment of nucleus localization GO:0040023 16 8 3,000 4,895E-08 5,889E-06 ! negative regulation of protein kinase activity GO:0006469 130 67 6,000 6,119E-08 7,01E-06 ! negative regulation of kinase activity GO:0033673 131 68 6,000 6,791E-08 7,427E-06 ! negative regulation of transferase activity GO:0051348 140 72 6,000 1,014E-07 1,061E-05 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 3,000 1,457E-07 1,46E-05 ! insulin receptor signaling pathway GO:0008286 64 26 4,000 2,174E-07 2,093E-05 ! nucleus localization GO:0051647 19 11 3,000 2,28E-07 2,109E-05 ! negative regulation of cell motion GO:0051271 134 55 5,000 4,28E-07 3,814E-05 ! negative regulation of protein kinase cascade GO:0010741 68 30 4,000 4,632E-07 3,98E-05 ! inner ear morphogenesis GO:0042472 47 31 4,000 5,5E-07 4,563E-05 ! cell projection assembly GO:0030031 120 66 5,000 1,28E-06 1,026E-04 ! cellular response to insulin stimulus GO:0032869 82 37 4,000 1,376E-06 1,068E-04 ! endothelial cell migration GO:0043542 28 17 3,000 1,604E-06 1,206E-04 ! inositol metabolic process GO:0006020 28 17 3,000 1,604E-06 1,17E-04 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 3,000 1,604E-06 1,135E-04 ! cardiac muscle tissue development GO:0048738 31 17 3,000 1,604E-06 1,103E-04 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 3,000 1,604E-06 1,072E-04 ! cell cycle checkpoint GO:0000075 137 69 5,000 1,667E-06 1,084E-04 ! negative regulation of cell size GO:0045792 134 69 5,000 1,667E-06 1,055E-04 ! ear morphogenesis GO:0042471 60 39 4,000 1,802E-06 1,112E-04 ! negative regulation of gliogenesis GO:0014014 18 6 2,000 2,748E-06 1,653E-04 GO:0045686|negative regulation of glial cell differentiation, ! positive regulation of pseudopodium assembly GO:0031274 14 6 2,000 2,748E-06 1,613E-04 GO:0031272|regulation of pseudopodium assembly, ! negative regulation of neuroblast proliferation GO:0007406 21 6 2,000 2,748E-06 1,574E-04 ! apoptotic mitochondrial changes GO:0008637 41 20 3,000 3,227E-06 1,805E-04 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 3,000 3,227E-06 1,764E-04 ! branching morphogenesis of a tube GO:0048754 97 45 4,000 3,729E-06 1,994E-04 ! negative regulation of cell migration GO:0030336 115 46 4,000 4,166E-06 2,179E-04 ! response to insulin stimulus GO:0032868 95 46 4,000 4,166E-06 2,133E-04 ! macrophage differentiation GO:0030225 11 7 2,000 4,79E-06 2,401E-04 ! positive regulation of cell cycle GO:0045787 89 48 4,000 5,16E-06 2,534E-04 ! negative regulation of transport GO:0051051 153 84 5,000 5,299E-06 2,55E-04 ! inner ear development GO:0048839 79 50 4,000 6,332E-06 2,987E-04 ! regulation of cell shape GO:0008360 125 51 4,000 6,991E-06 3,234E-04 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 2,000 7,635E-06 3,466E-04 ! Schwann cell differentiation GO:0014037 19 8 2,000 7,635E-06 3,402E-04 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 2,000 7,635E-06 3,34E-04 ! morphogenesis of a branching structure GO:0001763 111 52 4,000 7,702E-06 3,309E-04 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 3,000 8,255E-06 3,484E-04 ! negative regulation of cell development GO:0010721 73 25 3,000 8,255E-06 3,424E-04 GO:0050768|negative regulation of neurogenesis, ! regulation of neuron apoptosis GO:0043523 100 53 4,000 8,469E-06 3,453E-04 ! response to UV GO:0009411 104 53 4,000 8,469E-06 3,396E-04 ! positive regulation of MAP kinase activity GO:0043406 160 93 5,000 9,562E-06 3,771E-04 ! regulation of transcription factor import into nucleus GO:0042990 54 26 3,000 9,716E-06 3,771E-04 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 3,000 1,136E-05 4,338E-04 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 2,000 1,141E-05 4,289E-04 ! lipid modification GO:0030258 97 57 4,000 1,215E-05 4,498E-04 ! skeletal system morphogenesis GO:0048705 105 59 4,000 1,441E-05 5,252E-04 ! establishment of organelle localization GO:0051656 109 59 4,000 1,441E-05 5,174E-04 ! cellular response to extracellular stimulus GO:0031668 48 29 3,000 1,525E-05 5,396E-04 ! protein amino acid autophosphorylation GO:0046777 141 60 4,000 1,565E-05 5,457E-04 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 2,000 1,624E-05 5,58E-04 ! regulation of gliogenesis GO:0014013 23 10 2,000 1,624E-05 5,502E-04 GO:0045685|regulation of glial cell differentiation, ! response to peptide hormone stimulus GO:0043434 122 61 4,000 1,698E-05 5,673E-04 ! ear development GO:0043583 103 62 4,000 1,839E-05 6,061E-04 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 2,000 2,224E-05 7,231E-04 ! thymus development GO:0048538 27 11 2,000 2,224E-05 7,134E-04 ! metanephros development GO:0001656 74 32 3,000 2,281E-05 7,221E-04 ! regulation of protein import into nucleus GO:0042306 63 32 3,000 2,281E-05 7,127E-04 ! peripheral nervous system development GO:0007422 64 32 3,000 2,281E-05 7,036E-04 ! DNA damage checkpoint GO:0000077 71 33 3,000 2,585E-05 7,873E-04 ! negative regulation of protein transport GO:0051224 69 33 3,000 2,585E-05 7,774E-04 ! negative regulation of cell growth GO:0030308 132 67 4,000 2,688E-05 7,983E-04 ! placenta development GO:0001890 53 34 3,000 2,918E-05 8,561E-04 ! positive regulation of cellular catabolic process GO:0031331 31 12 2,000 2,954E-05 8,562E-04 ! regulation of B cell proliferation GO:0030888 20 12 2,000 2,954E-05 8,461E-04 ! regulation of cell projection assembly GO:0060491 30 12 2,000 2,954E-05 8,361E-04 ! negative regulation of mast cell proliferation GO:0070667 23 12 2,000 2,954E-05 8,264E-04 GO:0042130|negative regulation of T cell proliferation, ! embryonic skeletal system morphogenesis GO:0048704 59 35 3,000 3,281E-05 9,074E-04 ! DNA integrity checkpoint GO:0031570 75 36 3,000 3,676E-05 1,005E-03 ! phosphoinositide metabolic process GO:0030384 128 72 4,000 3,813E-05 1,031E-03 ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 2,000 3,825E-05 1,023E-03 ! regulation of monooxygenase activity GO:0032768 33 13 2,000 3,825E-05 1,011E-03 ! cytoplasmic sequestering of protein GO:0051220 24 13 2,000 3,825E-05 1E-03 ! meiosis I GO:0007127 65 37 3,000 4,105E-05 1,062E-03 ! negative regulation of DNA binding GO:0043392 68 37 3,000 4,105E-05 1,051E-03 ! organelle localization GO:0051640 136 74 4,000 4,353E-05 1,102E-03 ! actin cytoskeleton reorganization GO:0031532 33 14 2,000 4,85E-05 1,215E-03 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 2,000 4,85E-05 1,203E-03 GO:0060675|ureteric bud morphogenesis, ! negative regulation of protein import into nucleus GO:0042308 30 14 2,000 4,85E-05 1,191E-03 ! negative regulation of binding GO:0051100 72 40 3,000 5,612E-05 1,364E-03 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 2,000 6,039E-05 1,453E-03 ! polyol metabolic process GO:0019751 66 41 3,000 6,193E-05 1,475E-03 ! regulation of intracellular protein transport GO:0033157 80 42 3,000 6,818E-05 1,608E-03 ! cellular response to hormone stimulus GO:0032870 167 82 4,000 7,131E-05 1,666E-03 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 2,000 7,404E-05 1,713E-03 ! negative regulation of leukocyte proliferation GO:0070664 31 16 2,000 7,404E-05 1,697E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 2,000 7,404E-05 1,681E-03 ! negative regulation of growth GO:0045926 155 84 4,000 8,001E-05 1,799E-03 ! tube morphogenesis GO:0035239 176 86 4,000 8,95E-05 1,994E-03 ! regulation of protein transport GO:0051223 154 87 4,000 9,456E-05 2,087E-03 GO:0070201|regulation of establishment of protein localization, ! regulation of nucleocytoplasmic transport GO:0046822 85 46 3,000 9,78E-05 2,139E-03 ! regulation of gene-specific transcription GO:0032583 96 46 3,000 9,78E-05 2,12E-03 ! regulation of DNA binding GO:0051101 155 88 4,000 9,984E-05 2,145E-03 ! gland development GO:0048732 206 88 4,000 9,984E-05 2,126E-03 ! regulation of cell morphogenesis GO:0022604 215 89 4,000 1,053E-04 2,223E-03 ! regulation of mast cell proliferation GO:0070666 81 48 3,000 1,157E-04 2,42E-03 ! endocrine system development GO:0035270 104 49 3,000 1,254E-04 2,602E-03 ! embryonic skeletal system development GO:0048706 85 51 3,000 1,468E-04 3,018E-03 ! regulation of leukocyte proliferation GO:0070663 88 51 3,000 1,468E-04 2,993E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! cellular response to starvation GO:0009267 33 20 2,000 1,484E-04 3,001E-03 ! negative regulation of T cell activation GO:0050868 40 20 2,000 1,484E-04 2,976E-03 ! regulation of protein localization GO:0032880 176 97 4,000 1,582E-04 3,145E-03 ! regulation of angiogenesis GO:0045765 114 52 3,000 1,584E-04 3,123E-03 ! reciprocal meiotic recombination GO:0007131 39 21 2,000 1,725E-04 3,375E-03 ! negative regulation of intracellular transport GO:0032387 41 21 2,000 1,725E-04 3,347E-03 ! skeletal muscle tissue development GO:0007519 186 99 4,000 1,741E-04 3,351E-03 GO:0060538|skeletal muscle organ development, ! cell cycle arrest GO:0007050 213 100 4,000 1,825E-04 3,485E-03 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 1,99E-04 3,77E-03 ! ureteric bud development GO:0001657 43 22 2,000 1,99E-04 3,74E-03 ! skeletal muscle fiber development GO:0048741 111 56 3,000 2,114E-04 3,943E-03 ! muscle fiber development GO:0048747 112 57 3,000 2,264E-04 4,191E-03 ! regulation of intracellular transport GO:0032386 101 57 3,000 2,264E-04 4,159E-03 ! myeloid leukocyte differentiation GO:0002573 40 23 2,000 2,28E-04 4,155E-03 ! activation of pro-apoptotic gene products GO:0008633 47 23 2,000 2,28E-04 4,124E-03 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 2,000 2,28E-04 4,093E-03 ! protein import into nucleus, translocation GO:0000060 46 24 2,000 2,595E-04 4,626E-03 ! regulation of cellular catabolic process GO:0031329 52 24 2,000 2,595E-04 4,592E-03 ! negative regulation of phosphorylation GO:0042326 47 24 2,000 2,595E-04 4,558E-03 ! pallium development GO:0021543 49 24 2,000 2,595E-04 4,525E-03 ! regulation of oxidoreductase activity GO:0051341 46 24 2,000 2,595E-04 4,493E-03 ! protein tetramerization GO:0051262 52 24 2,000 2,595E-04 4,46E-03 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 2,673E-04 4,561E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 2,673E-04 4,528E-03 ! anagen GO:0042640 6 5 1,000 2,673E-04 4,497E-03 ! smooth muscle tissue development GO:0048745 28 5 1,000 2,673E-04 4,466E-03 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 1,000 2,673E-04 4,435E-03 ! microvillus organization GO:0032528 7 5 1,000 2,673E-04 4,404E-03 GO:0030033|microvillus assembly, ! response to food GO:0032094 6 5 1,000 2,673E-04 4,374E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 2,673E-04 4,345E-03 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 1,000 2,673E-04 4,316E-03 ! cellular glucose homeostasis GO:0001678 5 5 1,000 2,673E-04 4,287E-03 ! early endosome to late endosome transport GO:0045022 12 5 1,000 2,673E-04 4,259E-03 ! meiotic chromosome segregation GO:0045132 7 5 1,000 2,673E-04 4,23E-03 ! forebrain morphogenesis GO:0048853 13 5 1,000 2,673E-04 4,203E-03 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 1,000 2,673E-04 4,176E-03 GO:0022011|myelination in the peripheral nervous system, ! stem cell division GO:0017145 11 5 1,000 2,673E-04 4,149E-03 GO:0048103|somatic stem cell division, ! DNA damage response, signal transduction GO:0042770 128 60 3,000 2,762E-04 4,259E-03 ! kidney development GO:0001822 122 60 3,000 2,762E-04 4,232E-03 ! myelination GO:0042552 45 25 2,000 2,938E-04 4,474E-03 ! response to starvation GO:0042594 42 25 2,000 2,938E-04 4,446E-03 ! interaction with host GO:0051701 62 25 2,000 2,938E-04 4,418E-03 ! cellular response to nutrient levels GO:0031669 41 25 2,000 2,938E-04 4,391E-03 ! regulation of protein complex assembly GO:0043254 117 61 3,000 2,943E-04 4,372E-03 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 2,000 3,309E-04 4,884E-03 GO:0045936|negative regulation of phosphate metabolic process, ! positive regulation of nuclear division GO:0051785 40 26 2,000 3,309E-04 4,854E-03 GO:0045840|positive regulation of mitosis, ! regulation of lipid metabolic process GO:0019216 115 63 3,000 3,333E-04 4,86E-03 ! regulation of fibroblast proliferation GO:0048145 52 27 2,000 3,708E-04 5,374E-03 ! positive regulation of cell projection organization GO:0031346 58 27 2,000 3,708E-04 5,342E-03 ! negative regulation of lymphocyte activation GO:0051250 53 27 2,000 3,708E-04 5,31E-03 ! myeloid cell differentiation GO:0030099 111 65 3,000 3,758E-04 5,349E-03 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 1,000 3,995E-04 5,654E-03 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 1,000 3,995E-04 5,621E-03 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 1,000 3,995E-04 5,589E-03 ! male sex determination GO:0030238 15 6 1,000 3,995E-04 5,556E-03 ! establishment of spindle localization GO:0051293 12 6 1,000 3,995E-04 5,524E-03 GO:0051653|spindle localization, ! astrocyte development GO:0014002 15 6 1,000 3,995E-04 5,493E-03 ! purine base biosynthetic process GO:0009113 17 6 1,000 3,995E-04 5,462E-03 ! positive regulation of cytokine production during immune response GO:0002720 9 6 1,000 3,995E-04 5,431E-03 ! enucleate erythrocyte differentiation GO:0043353 12 6 1,000 3,995E-04 5,4E-03 ! hair follicle maturation GO:0048820 7 6 1,000 3,995E-04 5,37E-03 ! Schwann cell development GO:0014044 15 6 1,000 3,995E-04 5,34E-03 ! negative regulation of B cell activation GO:0050869 13 6 1,000 3,995E-04 5,311E-03 ! activation of MAPK activity GO:0000187 115 67 3,000 4,22E-04 5,578E-03 ! negative regulation of protein complex assembly GO:0031333 59 29 2,000 4,597E-04 6,044E-03 ! negative regulation of neuron apoptosis GO:0043524 56 29 2,000 4,597E-04 6,011E-03 ! urogenital system development GO:0001655 137 69 3,000 4,721E-04 6,14E-03 ! ensheathment of neurons GO:0007272 57 30 2,000 5,088E-04 6,582E-03 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 56 30 2,000 5,088E-04 6,547E-03 ! regulation of B cell activation GO:0050864 50 30 2,000 5,088E-04 6,512E-03 ! regulation of helicase activity GO:0051095 15 7 1,000 5,574E-04 7,096E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 5,574E-04 7,059E-03 ! adrenal gland development GO:0030325 17 7 1,000 5,574E-04 7,022E-03 ! regulation of granule cell precursor proliferation GO:0021936 13 7 1,000 5,574E-04 6,985E-03 GO:0021940|positive regulation of granule cell precursor proliferation, ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 5,574E-04 6,949E-03 ! fibrinolysis GO:0042730 10 7 1,000 5,574E-04 6,913E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 5,574E-04 6,878E-03 ! positive regulation of monooxygenase activity GO:0032770 12 7 1,000 5,574E-04 6,843E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 5,574E-04 6,808E-03 ! response to tumor cell GO:0002347 13 7 1,000 5,574E-04 6,773E-03 ! regulation of respiratory burst GO:0060263 11 7 1,000 5,574E-04 6,739E-03 ! negative regulation of transcription regulator activity GO:0090048 58 31 2,000 5,612E-04 6,751E-03 GO:0043433|negative regulation of transcription factor activity, ! regulation of transcription factor activity GO:0051090 126 74 3,000 6,158E-04 7,371E-03 GO:0090046|regulation of transcription regulator activity, ! meiosis GO:0007126 121 74 3,000 6,158E-04 7,335E-03 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of MAP kinase activity GO:0043407 69 32 2,000 6,169E-04 7,311E-03 ! positive regulation of catabolic process GO:0009896 64 32 2,000 6,169E-04 7,276E-03 ! cell-matrix adhesion GO:0007160 163 75 3,000 6,479E-04 7,604E-03 ! meiotic cell cycle GO:0051321 122 75 3,000 6,479E-04 7,567E-03 ! positive regulation of gene-specific transcription GO:0043193 65 33 2,000 6,76E-04 7,857E-03 ! cell fate specification GO:0001708 52 33 2,000 6,76E-04 7,819E-03 ! regulation of catabolic process GO:0009894 161 76 3,000 6,811E-04 7,841E-03 ! glial cell differentiation GO:0010001 63 34 2,000 7,386E-04 8,462E-03 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 2,000 7,386E-04 8,422E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 7,407E-04 8,406E-03 ! astrocyte differentiation GO:0048708 18 8 1,000 7,407E-04 8,366E-03 ! ER overload response GO:0006983 12 8 1,000 7,407E-04 8,327E-03 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 7,407E-04 8,289E-03 ! cerebral cortex neuron differentiation GO:0021895 16 8 1,000 7,407E-04 8,25E-03 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 1,000 7,407E-04 8,212E-03 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 1,000 7,407E-04 8,175E-03 ! negative regulation of secretion GO:0051048 63 35 2,000 8,048E-04 8,841E-03 ! telencephalon development GO:0021537 68 35 2,000 8,048E-04 8,801E-03 ! response to hypoxia GO:0001666 171 81 3,000 8,657E-04 9,425E-03 ! cell-substrate adhesion GO:0031589 171 81 3,000 8,657E-04 9,382E-03 ! regulation of neuron differentiation GO:0045664 167 81 3,000 8,657E-04 9,34E-03 ! maintenance of protein location in cell GO:0032507 86 36 2,000 8,746E-04 9,394E-03 ! negative regulation of cell activation GO:0050866 65 36 2,000 8,746E-04 9,352E-03 ! establishment or maintenance of cell polarity GO:0007163 83 37 2,000 9,481E-04 0,01009364 ! response to oxygen levels GO:0070482 176 83 3,000 9,485E-04 0,01005317 ! regulation of developmental growth GO:0048638 15 9 1,000 9,49E-04 0,01001479 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 9,49E-04 9,971E-03 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 1,000 9,49E-04 9,928E-03 GO:0010469|regulation of receptor activity, ! artery development GO:0060840 24 9 1,000 9,49E-04 9,885E-03 GO:0048844|artery morphogenesis, ! regulation of glycolysis GO:0006110 21 9 1,000 9,49E-04 9,842E-03 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 1,000 9,49E-04 9,8E-03 ! middle ear morphogenesis GO:0042474 14 9 1,000 9,49E-04 9,758E-03 ! receptor clustering GO:0043113 18 9 1,000 9,49E-04 9,716E-03 ! motor axon guidance GO:0008045 16 9 1,000 9,49E-04 9,675E-03 ! protein heterooligomerization GO:0051291 16 9 1,000 9,49E-04 9,634E-03 ! induction of an organ GO:0001759 14 9 1,000 9,49E-04 9,594E-03 ! regulation of macrophage differentiation GO:0045649 15 9 1,000 9,49E-04 9,554E-03 ! purine base metabolic process GO:0006144 21 9 1,000 9,49E-04 9,514E-03 ! carbohydrate homeostasis GO:0033500 53 38 2,000 1,025E-03 0,01023763 GO:0042593|glucose homeostasis, ! mitochondrion organization GO:0007005 148 86 3,000 1,083E-03 0,01076659 ! regulation of action potential in neuron GO:0019228 73 39 2,000 1,107E-03 0,01095764 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 1,000 1,182E-03 0,01165758 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 1,182E-03 0,01161 ! glucan biosynthetic process GO:0009250 14 10 1,000 1,182E-03 0,01156281 GO:0005978|glycogen biosynthetic process, ! nucleobase biosynthetic process GO:0046112 24 10 1,000 1,182E-03 0,01151599 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 1,182E-03 0,01146956 ! regulation of bone resorption GO:0045124 25 10 1,000 1,182E-03 0,0114235 ! brain morphogenesis GO:0048854 23 10 1,000 1,182E-03 0,0113778 ! positive regulation of phagocytosis GO:0050766 13 10 1,000 1,182E-03 0,01133247 ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 1,182E-03 0,0112875 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 1,182E-03 0,01124289 GO:0043470|regulation of carbohydrate catabolic process, ! localization within membrane GO:0051668 20 10 1,000 1,182E-03 0,01119862 ! maintenance of protein location GO:0045185 91 40 2,000 1,192E-03 0,0112457 ! cytokinesis GO:0000910 72 40 2,000 1,192E-03 0,01120177 ! gliogenesis GO:0042063 88 41 2,000 1,281E-03 0,01199332 ! regulation of T cell proliferation GO:0042129 71 41 2,000 1,281E-03 0,01194683 ! regulation of T cell differentiation GO:0045580 70 41 2,000 1,281E-03 0,01190071 ! ossification GO:0001503 188 90 3,000 1,282E-03 0,01186569 ! regulation of cell cycle process GO:0010564 149 90 3,000 1,282E-03 0,01182023 ! bone development GO:0060348 189 91 3,000 1,336E-03 0,01226708 ! thyroid gland development GO:0030878 26 11 1,000 1,44E-03 0,01317361 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 1,44E-03 0,01312371 ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 1,000 1,44E-03 0,01307419 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 1,000 1,44E-03 0,01302504 ! positive regulation of T cell mediated immunity GO:0002711 24 11 1,000 1,44E-03 0,01297626 ! neuroblast proliferation GO:0007405 24 11 1,000 1,44E-03 0,01292784 ! developmental induction GO:0031128 19 11 1,000 1,44E-03 0,01287978 GO:0045168|cell-cell signaling involved in cell fate specification, ! regulation of embryonic development GO:0045995 27 11 1,000 1,44E-03 0,01283208 ! regulation of epithelial cell proliferation GO:0050678 111 43 2,000 1,472E-03 0,01306739 ! regulation of T cell activation GO:0050863 158 94 3,000 1,506E-03 0,0133205 ! forebrain development GO:0030900 188 95 3,000 1,566E-03 0,01379953 ! maintenance of location in cell GO:0051651 97 44 2,000 1,574E-03 0,0138173 ! leukocyte differentiation GO:0002521 202 96 3,000 1,627E-03 0,01423747 ! induction of apoptosis by intracellular signals GO:0008629 93 45 2,000 1,68E-03 0,01464115 ! virus-host interaction GO:0019048 29 12 1,000 1,722E-03 0,01495805 ! cartilage condensation GO:0001502 20 12 1,000 1,722E-03 0,01490424 ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 1,722E-03 0,01485082 ! hippocampus development GO:0021766 26 12 1,000 1,722E-03 0,01479778 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 1,722E-03 0,01474512 ! focal adhesion formation GO:0048041 35 12 1,000 1,722E-03 0,01469283 ! entry into host cell GO:0030260 32 12 1,000 1,722E-03 0,01464091 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! regulation of phagocytosis GO:0050764 16 12 1,000 1,722E-03 0,01458936 ! cranial nerve development GO:0021545 20 12 1,000 1,722E-03 0,01453817 ! histone acetylation GO:0016573 26 12 1,000 1,722E-03 0,01448734 ! autonomic nervous system development GO:0048483 24 12 1,000 1,722E-03 0,01443686 ! peptidyl-lysine modification GO:0018205 21 12 1,000 1,722E-03 0,01438673 ! T cell homeostasis GO:0043029 25 12 1,000 1,722E-03 0,01433695 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 1,000 1,722E-03 0,01428751 ! activation of caspase activity GO:0006919 84 48 2,000 2,024E-03 0,01673395 ! regulation of lymphocyte differentiation GO:0045619 81 48 2,000 2,024E-03 0,01667665 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 1,000 2,028E-03 0,01665524 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! response to X-ray GO:0010165 25 13 1,000 2,028E-03 0,01659859 ! cellular carbohydrate catabolic process GO:0044275 15 13 1,000 2,028E-03 0,01654233 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 2,028E-03 0,01648644 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of cytokine production during immune response GO:0002718 23 13 1,000 2,028E-03 0,01643093 ! regulation of cellular pH GO:0030641 22 13 1,000 2,028E-03 0,01637579 ! positive regulation of Ras GTPase activity GO:0032320 35 13 1,000 2,028E-03 0,01632103 ! embryonic placenta development GO:0001892 23 13 1,000 2,028E-03 0,01626662 ! regulation of action potential GO:0001508 95 49 2,000 2,148E-03 0,0171677 ! regulation of cell projection organization GO:0031344 121 50 2,000 2,276E-03 0,01813398 ! negative regulation of immune system process GO:0002683 95 50 2,000 2,276E-03 0,01807413 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 2,358E-03 0,01866405 ! positive regulation of GTPase activity GO:0043547 36 14 1,000 2,358E-03 0,01860285 ! response to gamma radiation GO:0010332 28 14 1,000 2,358E-03 0,01854206 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 2,358E-03 0,01848166 ! epithelial tube morphogenesis GO:0060562 98 51 2,000 2,409E-03 0,01882036 ! positive regulation of growth GO:0045927 90 52 2,000 2,547E-03 0,0198325 ! pituitary gland development GO:0021983 29 15 1,000 2,712E-03 0,02104651 ! G1/S transition checkpoint GO:0031575 40 15 1,000 2,712E-03 0,02097884 ! regulation of T cell mediated immunity GO:0002709 33 15 1,000 2,712E-03 0,0209116 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 2,712E-03 0,02084479 ! lymphocyte homeostasis GO:0002260 30 15 1,000 2,712E-03 0,0207784 ! positive regulation of caspase activity GO:0043280 95 55 2,000 2,989E-03 0,0228332 GO:0010952|positive regulation of peptidase activity, ! regulation of protein catabolic process GO:0042176 116 55 2,000 2,989E-03 0,02276094 ! aging GO:0007568 103 55 2,000 2,989E-03 0,02268914 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 3,089E-03 0,02336802 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 1,000 3,089E-03 0,02329476 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 1,000 3,089E-03 0,02322197 ! activation of MAPKK activity GO:0000186 35 16 1,000 3,089E-03 0,02314962 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 1,000 3,089E-03 0,02307773 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 3,089E-03 0,02300628 ! regulation of DNA replication GO:0006275 101 56 2,000 3,147E-03 0,02336663 ! positive regulation of organelle organization GO:0010638 100 56 2,000 3,147E-03 0,02329473 ! positive regulation of cell migration GO:0030335 126 57 2,000 3,309E-03 0,02442062 ! maintenance of location GO:0051235 118 57 2,000 3,309E-03 0,02434594 ! negative regulation of cell cycle process GO:0010948 32 17 1,000 3,488E-03 0,02558872 ! signal complex assembly GO:0007172 41 17 1,000 3,488E-03 0,02551094 ! glial cell development GO:0021782 27 17 1,000 3,488E-03 0,02543364 ! limbic system development GO:0021761 36 17 1,000 3,488E-03 0,0253568 ! regulation of survival gene product expression GO:0045884 33 17 1,000 3,488E-03 0,02528042 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 3,488E-03 0,0252045 ! nucleobase metabolic process GO:0009112 37 17 1,000 3,488E-03 0,02512904 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 1,000 3,488E-03 0,02505403 ! negative regulation of blood coagulation GO:0030195 24 17 1,000 3,488E-03 0,02497946 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 1,000 3,488E-03 0,02490534 ! integrin-mediated signaling pathway GO:0007229 135 59 2,000 3,648E-03 0,02597121 ! positive regulation of anti-apoptosis GO:0045768 39 18 1,000 3,911E-03 0,02775822 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 3,911E-03 0,02767658 ! protein amino acid ADP-ribosylation GO:0006471 33 18 1,000 3,911E-03 0,02759542 ! positive regulation of proteolysis GO:0045862 31 18 1,000 3,911E-03 0,02751473 ! glutamine metabolic process GO:0006541 29 18 1,000 3,911E-03 0,02743451 ! cell-substrate junction assembly GO:0007044 54 18 1,000 3,911E-03 0,02735476 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 3,911E-03 0,02727547 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 1,000 3,911E-03 0,02719664 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 3,911E-03 0,02711826 ! nerve development GO:0021675 28 18 1,000 3,911E-03 0,02704033 ! viral reproductive process GO:0022415 126 62 2,000 4,197E-03 0,02893094 ! positive regulation of angiogenesis GO:0045766 44 19 1,000 4,356E-03 0,02994642 ! lipid phosphorylation GO:0046834 35 19 1,000 4,356E-03 0,02986111 ! cerebral cortex development GO:0021987 36 19 1,000 4,356E-03 0,02977627 ! actin filament bundle formation GO:0051017 42 19 1,000 4,356E-03 0,02969192 ! neuromuscular junction development GO:0007528 34 19 1,000 4,356E-03 0,02960805 ! regulation of endothelial cell migration GO:0010594 44 19 1,000 4,356E-03 0,02952464 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 1,000 4,356E-03 0,02944171 ! visual learning GO:0008542 36 19 1,000 4,356E-03 0,02935924 ! G1 phase GO:0051318 40 19 1,000 4,356E-03 0,02927723 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 1,000 4,356E-03 0,02919568 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 1,000 4,356E-03 0,02911458 ! regulation of mitosis GO:0007088 105 63 2,000 4,39E-03 0,02925665 GO:0051783|regulation of nuclear division, ! positive regulation of cell motion GO:0051272 146 64 2,000 4,588E-03 0,03049497 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 1,000 4,824E-03 0,03197286 ! protein amino acid acetylation GO:0006473 39 20 1,000 4,824E-03 0,03188502 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 4,824E-03 0,03179767 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 4,824E-03 0,03171079 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of interleukin-2 production GO:0032663 35 20 1,000 4,824E-03 0,03162438 ! diencephalon development GO:0021536 34 20 1,000 4,824E-03 0,03153845 ! peptidyl-serine modification GO:0018209 43 20 1,000 4,824E-03 0,03145298 ! camera-type eye morphogenesis GO:0048593 42 20 1,000 4,824E-03 0,03136797 ! negative regulation of coagulation GO:0050819 29 20 1,000 4,824E-03 0,03128342 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 4,824E-03 0,03119932 ! actin filament organization GO:0007015 148 66 2,000 5,001E-03 0,03225998 ! developmental maturation GO:0021700 116 66 2,000 5,001E-03 0,03217373 ! lung development GO:0030324 144 67 2,000 5,216E-03 0,03346514 ! homeostasis of number of cells GO:0048872 114 67 2,000 5,216E-03 0,03337614 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 2,000 5,216E-03 0,03328761 ! axis specification GO:0009798 38 21 1,000 5,313E-03 0,03382052 ! cell structure disassembly during apoptosis GO:0006921 30 21 1,000 5,313E-03 0,03373128 ! cell aging GO:0007569 44 21 1,000 5,313E-03 0,03364251 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 1,000 5,313E-03 0,03355421 ! regulation of Rho GTPase activity GO:0032319 43 21 1,000 5,313E-03 0,03346638 ! collagen fibril organization GO:0030199 59 21 1,000 5,313E-03 0,033379 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 1,000 5,313E-03 0,03329207 ! viral reproduction GO:0016032 134 68 2,000 5,436E-03 0,03397155 ! positive regulation of protein catabolic process GO:0045732 38 22 1,000 5,825E-03 0,03630749 ! calcium-independent cell-cell adhesion GO:0016338 30 22 1,000 5,825E-03 0,03621368 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 5,825E-03 0,03612034 ! apoptotic nuclear changes GO:0030262 32 22 1,000 5,825E-03 0,03602749 ! positive regulation of adaptive immune response GO:0002821 39 22 1,000 5,825E-03 0,03593511 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 5,825E-03 0,0358432 ! positive regulation of B cell activation GO:0050871 38 22 1,000 5,825E-03 0,03575177 ! activation of JUN kinase activity GO:0007257 42 22 1,000 5,825E-03 0,0356608 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 1,000 5,825E-03 0,03557029 ! protein stabilization GO:0050821 39 22 1,000 5,825E-03 0,03548024 ! respiratory tube development GO:0030323 150 70 2,000 5,893E-03 0,03580335 ! regulation of MAPKKK cascade GO:0043408 142 71 2,000 6,13E-03 0,03714801 ! positive regulation of DNA replication GO:0045740 43 23 1,000 6,358E-03 0,03843515 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 6,358E-03 0,03833882 ! regulation of anti-apoptosis GO:0045767 53 23 1,000 6,358E-03 0,03824297 ! gluconeogenesis GO:0006094 33 23 1,000 6,358E-03 0,0381476 ! visual behavior GO:0007632 42 23 1,000 6,358E-03 0,03805271 ! sex determination GO:0007530 47 23 1,000 6,358E-03 0,03795828 ! negative regulation of catabolic process GO:0009895 50 23 1,000 6,358E-03 0,03786433 ! regulation of caspase activity GO:0043281 122 72 2,000 6,372E-03 0,03785408 ! respiratory system development GO:0060541 153 72 2,000 6,372E-03 0,03776084 ! regulation of endopeptidase activity GO:0052548 125 74 2,000 6,874E-03 0,04063397 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 6,912E-03 0,04076243 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 1,000 6,912E-03 0,04066277 ! spinal cord development GO:0021510 47 24 1,000 6,912E-03 0,04056359 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 1,000 6,912E-03 0,0404649 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukocyte homeostasis GO:0001776 44 24 1,000 6,912E-03 0,04036668 ! vasculogenesis GO:0001570 46 25 1,000 7,488E-03 0,04362175 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 7,488E-03 0,04351638 ! negative regulation of DNA replication GO:0008156 42 25 1,000 7,488E-03 0,04341152 ! receptor metabolic process GO:0043112 46 25 1,000 7,488E-03 0,04330717 ! osteoblast differentiation GO:0001649 60 25 1,000 7,488E-03 0,04320332 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 7,488E-03 0,04309996 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 1,000 7,488E-03 0,04299709 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 1,000 7,488E-03 0,04289472 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 1,000 7,488E-03 0,04279283 ! regulation of blood coagulation GO:0030193 40 25 1,000 7,488E-03 0,04269143 ! liver development GO:0001889 53 25 1,000 7,488E-03 0,0425905 ! positive regulation of lymphocyte activation GO:0051251 127 77 2,000 7,669E-03 0,0435187 ! protein oligomerization GO:0051259 139 78 2,000 7,946E-03 0,04498284 ! initiation of viral infection GO:0019059 57 26 1,000 8,084E-03 0,04565906 ! pyruvate metabolic process GO:0006090 38 26 1,000 8,084E-03 0,04555213 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 1,000 8,084E-03 0,0454457 ! molting cycle process GO:0022404 50 26 1,000 8,084E-03 0,04533977 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! regulation of endothelial cell proliferation GO:0001936 57 26 1,000 8,084E-03 0,04523432 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 8,084E-03 0,04512937 ! positive regulation of JUN kinase activity GO:0043507 51 26 1,000 8,084E-03 0,04502491 ! activation of protein kinase activity GO:0032147 147 79 2,000 8,228E-03 0,04572172 ! regulation of peptidase activity GO:0052547 134 79 2,000 8,228E-03 0,04561637 ! positive regulation of phosphorylation GO:0042327 129 79 2,000 8,228E-03 0,0455115 ! regulation of adenylate cyclase activity GO:0045761 156 80 2,000 8,517E-03 0,04699858 ! protein import into nucleus GO:0006606 158 80 2,000 8,517E-03 0,04689104 ! protein amino acid acylation GO:0043543 55 27 1,000 8,701E-03 0,04779783 ! mitochondrial membrane organization GO:0007006 57 27 1,000 8,701E-03 0,04768895 ! base-excision repair GO:0006284 41 27 1,000 8,701E-03 0,04758056 ! regulation of chromosome organization GO:0033044 42 27 1,000 8,701E-03 0,04747267 ! negative regulation of neuron differentiation GO:0045665 42 27 1,000 8,701E-03 0,04736527 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 2,000 8,811E-03 0,04785418 GO:0045937|positive regulation of phosphate metabolic process, ! nuclear import GO:0051170 161 81 2,000 8,811E-03 0,0477464 ! regulation of cAMP biosynthetic process GO:0030817 161 82 2,000 9,111E-03 0,04926208 ! regulation of cyclase activity GO:0031279 159 82 2,000 9,111E-03 0,04915163 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 9,339E-03 0,05026689 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 9,339E-03 0,05015468 ! regulation of JUN kinase activity GO:0043506 58 28 1,000 9,339E-03 0,05004298 ! regulation of lyase activity GO:0051339 160 83 2,000 9,417E-03 0,05035136 ! regulation of cAMP metabolic process GO:0030814 168 84 2,000 9,729E-03 0,05190445 ! regulation of pH GO:0006885 43 29 1,000 9,997E-03 0,05321186 ! regulation of production of molecular mediator of immune response GO:0002700 61 29 1,000 9,997E-03 0,0530944 ! cell fate determination GO:0001709 60 29 1,000 9,997E-03 0,05297745 ! regulation of coagulation GO:0050818 46 29 1,000 9,997E-03 0,05286102 ! positive regulation of cell activation GO:0050867 145 85 2,000 0,01004741 0,05301332 GO:0002696|positive regulation of leukocyte activation, ! cell junction assembly GO:0034329 78 30 1,000 0,01067427 0,0561976 ! positive regulation of multicellular organism growth GO:0040018 51 30 1,000 0,01067427 0,05607489 ! eye morphogenesis GO:0048592 60 30 1,000 0,01067427 0,05595273 ! response to heat GO:0009408 50 30 1,000 0,01067427 0,05583109 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 2,000 0,01070146 0,05585188 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! protein localization in nucleus GO:0034504 176 87 2,000 0,01070146 0,05573099 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 1,000 0,01137173 0,05909368 ! erythrocyte differentiation GO:0030218 55 31 1,000 0,01137173 0,05896633 ! mesoderm formation GO:0001707 69 31 1,000 0,01137173 0,05883952 ! positive regulation of immune effector process GO:0002699 67 31 1,000 0,01137173 0,05871325 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 2,000 0,01172783 0,06042218 ! spindle organization GO:0007051 46 32 1,000 0,01208872 0,0621484 ! pigment biosynthetic process GO:0046148 66 32 1,000 0,01208872 0,06201589 ! response to ionizing radiation GO:0010212 65 32 1,000 0,01208872 0,06188394 ! hexose biosynthetic process GO:0019319 48 32 1,000 0,01208872 0,06175255 ! regulation of nucleotide metabolic process GO:0006140 182 93 2,000 0,01280897 0,0652932 ! carbohydrate biosynthetic process GO:0016051 141 93 2,000 0,01280897 0,06515516 ! regulation of membrane potential GO:0042391 164 93 2,000 0,01280897 0,0650177 ! formation of primary germ layer GO:0001704 72 33 1,000 0,01282502 0,06496211 ! positive regulation of endocytosis GO:0045807 50 34 1,000 0,01358042 0,06864391 ! mesoderm morphogenesis GO:0048332 76 34 1,000 0,01358042 0,0685 ! regulation of DNA metabolic process GO:0051052 178 97 2,000 0,01433643 0,07216202 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 0,01435471 0,07210318 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 0,01435471 0,07195297 ! calcium-mediated signaling GO:0019722 62 35 1,000 0,01435471 0,07180338 ! mitotic sister chromatid segregation GO:0000070 57 36 1,000 0,01514766 0,07561257 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 1,000 0,01514766 0,07545603 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! cell junction organization GO:0034330 86 36 1,000 0,01514766 0,07530012 ! regulation of proteolysis GO:0030162 72 36 1,000 0,01514766 0,07514487 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 1,000 0,01514766 0,07499025 ! androgen receptor signaling pathway GO:0030521 74 36 1,000 0,01514766 0,07483626 ! monosaccharide biosynthetic process GO:0046364 52 36 1,000 0,01514766 0,07468291 ! sister chromatid segregation GO:0000819 58 37 1,000 0,01595906 0,07852248 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 0,01595906 0,07836223 ! glycogen metabolic process GO:0005977 61 37 1,000 0,01595906 0,07820264 ! pigment metabolic process GO:0042440 80 37 1,000 0,01595906 0,07804369 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 0,0167887 0,08193432 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 0,0167887 0,08176846 ! nucleus organization GO:0006997 67 38 1,000 0,0167887 0,08160327 ! erythrocyte homeostasis GO:0034101 64 38 1,000 0,0167887 0,08143875 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 0,0167887 0,08127489 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! glucan metabolic process GO:0044042 62 38 1,000 0,0167887 0,08111168 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 86 39 1,000 0,01763638 0,08503633 ! learning GO:0007612 77 39 1,000 0,01763638 0,08486625 ! segmentation GO:0035282 67 39 1,000 0,01763638 0,08469686 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 1,000 0,01763638 0,08452814 ! T cell differentiation GO:0030217 81 41 1,000 0,019385 0,09272426 ! dorsal/ventral pattern formation GO:0009953 68 41 1,000 0,019385 0,09254028 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,02028553 0,09664748 GO:0090047|positive regulation of transcription regulator activity, ! alcohol biosynthetic process GO:0046165 59 42 1,000 0,02028553 0,09645648 ! regulation of leukocyte mediated immunity GO:0002703 79 42 1,000 0,02028553 0,09626623 ! regulation of protein secretion GO:0050708 71 42 1,000 0,02028553 0,09607673 ! regulation of myeloid cell differentiation GO:0045637 98 42 1,000 0,02028553 0,09588797 ! epithelial cell differentiation GO:0030855 79 43 1,000 0,02120327 0,10002953 ! energy reserve metabolic process GO:0006112 74 43 1,000 0,02120327 0,09983378 ! glucose transport GO:0015758 65 43 1,000 0,02120327 0,09963879 ! striated muscle cell differentiation GO:0051146 82 43 1,000 0,02120327 0,09944457 ! phagocytosis GO:0006909 90 43 1,000 0,02120327 0,09925109 ! hexose transport GO:0008645 67 44 1,000 0,02213802 0,10342538 GO:0015749|monosaccharide transport, ! double-strand break repair GO:0006302 81 44 1,000 0,02213802 0,10322494 ! B cell differentiation GO:0030183 107 44 1,000 0,02213802 0,10302528 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 1,000 0,02213802 0,10282639 ! developmental growth GO:0048589 82 44 1,000 0,02213802 0,10262826 ! regulation of actin filament polymerization GO:0030833 87 45 1,000 0,02308957 0,10683368 ! polysaccharide biosynthetic process GO:0000271 70 45 1,000 0,02308957 0,10662863 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 1,000 0,02405774 0,11088683 ! pigmentation GO:0043473 100 46 1,000 0,02405774 0,11067481 ! positive regulation of protein transport GO:0051222 72 46 1,000 0,02405774 0,1104636 ! endosome transport GO:0016197 108 47 1,000 0,02504232 0,11476539 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,02504232 0,1145472 ! positive regulation of cyclase activity GO:0031281 103 47 1,000 0,02504232 0,11432985 ! regulation of adaptive immune response GO:0002819 84 47 1,000 0,02504232 0,11411331 ! JNK cascade GO:0007254 91 47 1,000 0,02504232 0,1138976 ! regulation of JNK cascade GO:0046328 94 47 1,000 0,02504232 0,1136827 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,02579637 0,11688524 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,02579637 0,11666553 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02579637 0,11644664 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,02579637 0,11622858 ! neuron fate determination GO:0048664 7 5 0,000 0,02579637 0,11601133 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02579637 0,11579489 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,02579637 0,11557926 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,02579637 0,11536442 ! polyol transport GO:0015791 12 5 0,000 0,02579637 0,11515039 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,02579637 0,11493715 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02579637 0,11472469 ! response to superoxide GO:0000303 10 5 0,000 0,02579637 0,11451303 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02579637 0,11430214 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,02579637 0,11409202 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,02579637 0,11388268 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02579637 0,1136741 ! female meiosis GO:0007143 7 5 0,000 0,02579637 0,11346629 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02579637 0,11325923 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02579637 0,11305293 ! cobalt ion transport GO:0006824 11 5 0,000 0,02579637 0,11284738 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,02579637 0,11264258 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,02579637 0,11243851 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,02579637 0,11223519 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02579637 0,1120326 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,02579637 0,11183074 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,02579637 0,1116296 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02579637 0,11142919 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,02579637 0,1112295 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,02579637 0,11103052 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02579637 0,11083225 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02579637 0,11063469 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02579637 0,11043783 ! negative chemotaxis GO:0050919 14 5 0,000 0,02579637 0,11024167 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02579637 0,11004621 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02579637 0,10985143 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,02579637 0,10965735 ! behavioral response to pain GO:0048266 9 5 0,000 0,02579637 0,10946395 ! clathrin coat assembly GO:0048268 14 5 0,000 0,02579637 0,10927123 ! Notch receptor processing GO:0007220 8 5 0,000 0,02579637 0,10907919 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02579637 0,10888782 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02579637 0,10869713 ! micturition GO:0060073 9 5 0,000 0,02579637 0,1085071 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02579637 0,10831773 ! copulation GO:0007620 9 5 0,000 0,02579637 0,10812902 ! glial cell fate commitment GO:0021781 13 5 0,000 0,02579637 0,10794097 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,02579637 0,10775358 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02579637 0,10756683 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02579637 0,10738073 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02579637 0,10719527 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,02579637 0,10701045 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02579637 0,10682626 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02579637 0,10664271 ! grooming behavior GO:0007625 6 5 0,000 0,02579637 0,10645979 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02579637 0,1062775 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,02579637 0,10609583 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02579637 0,10591478 ! response to protozoan GO:0001562 10 5 0,000 0,02579637 0,10573434 ! lymph vessel development GO:0001945 10 5 0,000 0,02579637 0,10555452 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,02579637 0,10537531 ! endochondral ossification GO:0001958 16 5 0,000 0,02579637 0,10519671 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02579637 0,10501871 ! parathyroid gland development GO:0060017 13 5 0,000 0,02579637 0,10484132 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02579637 0,10466452 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02579637 0,10448832 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,02579637 0,10431271 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,02579637 0,10413768 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,02579637 0,10396325 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,02579637 0,1037894 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,02579637 0,10361613 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,02579637 0,10344343 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02579637 0,10327131 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02579637 0,10309977 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02579637 0,10292879 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,02579637 0,10275838 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,02579637 0,10258853 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02579637 0,10241924 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,02579637 0,10225051 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,02579637 0,10208234 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02579637 0,10191471 ! histidine catabolic process GO:0006548 6 5 0,000 0,02579637 0,10174764 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02579637 0,10158111 ! valine metabolic process GO:0006573 10 5 0,000 0,02579637 0,10141513 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,02579637 0,10124969 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02579637 0,10108479 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,02579637 0,10092042 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,02579637 0,10075659 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02579637 0,10059329 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,02579637 0,10043052 ! polyol catabolic process GO:0046174 7 5 0,000 0,02579637 0,10026827 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02579637 0,10010655 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02579637 0,09994535 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02579637 0,09978466 ! mitochondrial fission GO:0000266 8 5 0,000 0,02579637 0,09962449 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,02579637 0,09946484 ! mRNA transcription GO:0009299 9 5 0,000 0,02579637 0,0993057 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,02579637 0,09914706 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,02579637 0,09898893 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,02579637 0,09883131 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02579637 0,09867418 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02579637 0,09851756 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02579637 0,09836143 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02579637 0,09820579 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02579637 0,09805065 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02579637 0,09789599 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,02579637 0,09774183 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02579637 0,09758814 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,02579637 0,09743494 ! forebrain neuron development GO:0021884 13 5 0,000 0,02579637 0,09728223 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02579637 0,09712998 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02579637 0,09697822 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02579637 0,09682693 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02579637 0,09667611 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,02579637 0,09652575 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02579637 0,09637587 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,02579637 0,09622645 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,02579637 0,09607749 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02579637 0,095929 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,02579637 0,09578096 ! basic amino acid transport GO:0015802 11 5 0,000 0,02579637 0,09563337 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02579637 0,09548625 ! depyrimidination GO:0045008 10 5 0,000 0,02579637 0,09533957 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02579637 0,09519334 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02579637 0,09504756 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02579637 0,09490223 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,02579637 0,09475734 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,02579637 0,0946129 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02579637 0,09446889 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02579637 0,09432532 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,02579637 0,09418219 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,02579637 0,09403948 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02579637 0,09389722 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02579637 0,09375538 ! response to arsenic GO:0046685 10 5 0,000 0,02579637 0,09361397 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,02579637 0,09347298 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02579637 0,09333242 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,02579637 0,09319228 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,02579637 0,09305256 ! response to cadmium ion GO:0046686 7 5 0,000 0,02579637 0,09291326 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,02579637 0,09277438 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,02579637 0,09263591 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02579637 0,09249785 ! decidualization GO:0046697 11 5 0,000 0,02579637 0,09236021 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,02579637 0,09222297 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,02579637 0,09208614 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02579637 0,09194972 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02579637 0,0918137 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,02579637 0,09167808 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02579637 0,09154286 ! neural tube patterning GO:0021532 7 5 0,000 0,02579637 0,09140804 ! embryonic cleavage GO:0040016 6 5 0,000 0,02579637 0,09127362 ! peroxisome fission GO:0016559 5 5 0,000 0,02579637 0,09113959 ! histone demethylation GO:0016577 10 5 0,000 0,02579637 0,09100595 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,02579637 0,09087271 ! mitotic recombination GO:0006312 9 5 0,000 0,02579637 0,09073985 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02579637 0,09060739 ! metaphase plate congression GO:0051310 7 5 0,000 0,02579637 0,09047531 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02579637 0,09034361 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02579637 0,0902123 ! enteric nervous system development GO:0048484 8 5 0,000 0,02579637 0,09008136 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,02579637 0,08995081 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,02579637 0,08982064 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,02579637 0,08969084 ! muscle cell proliferation GO:0033002 11 5 0,000 0,02579637 0,08956141 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02579637 0,08943236 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,02579637 0,08930368 ! plasminogen activation GO:0031639 5 5 0,000 0,02579637 0,08917537 ! B cell homeostasis GO:0001782 13 5 0,000 0,02579637 0,08904743 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,02579637 0,08891986 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02579637 0,08879265 ! metaphase GO:0051323 8 5 0,000 0,02579637 0,0886658 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,02579637 0,08853932 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02579637 0,08841319 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02579637 0,08828743 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02579637 0,08816202 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02579637 0,08803696 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02579637 0,08791227 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,02579637 0,08778792 ! response to redox state GO:0051775 5 5 0,000 0,02579637 0,08766393 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,02579637 0,08754028 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,02579637 0,08741699 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02579637 0,08729404 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,02579637 0,08717143 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02579637 0,08704917 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,02579637 0,08692725 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02579637 0,08680568 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,02579637 0,08668444 ! striatum development GO:0021756 9 5 0,000 0,02579637 0,08656354 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,02579637 0,08644298 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,02579637 0,08632275 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02579637 0,08620286 ! glial cell migration GO:0008347 11 5 0,000 0,02579637 0,0860833 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02579637 0,08596407 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,02579637 0,08584517 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02579637 0,0857266 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02579637 0,08560836 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02579637 0,08549044 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02579637 0,08537285 ! neuroprotection GO:0043526 6 5 0,000 0,02579637 0,08525558 ! neural plate development GO:0001840 8 5 0,000 0,02579637 0,08513863 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,02579637 0,085022 ! regulation of sensory perception GO:0051931 7 5 0,000 0,02579637 0,08490569 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02579637 0,0847897 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02579637 0,08467402 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,02579637 0,08455866 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,02579637 0,08444362 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02579637 0,08432889 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02579637 0,08421446 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02579637 0,08410035 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02579637 0,08398655 ! spindle assembly GO:0051225 6 5 0,000 0,02579637 0,08387305 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,02579637 0,08375986 GO:0016226|iron-sulfur cluster assembly, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02579637 0,08364698 ! drug metabolic process GO:0017144 6 5 0,000 0,02579637 0,0835344 ! phospholipid scrambling GO:0017121 8 5 0,000 0,02579637 0,08342212 ! organ regeneration GO:0031100 7 5 0,000 0,02579637 0,08331015 ! carnitine metabolic process GO:0009437 7 5 0,000 0,02579637 0,08319847 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,02579637 0,08308709 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02579637 0,08297602 ! mitochondrial transport GO:0006839 82 48 1,000 0,02604312 0,08365788 ! cellular component disassembly GO:0022411 86 48 1,000 0,02604312 0,08354634 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 1,000 0,02604312 0,08343509 ! positive regulation of lyase activity GO:0051349 104 48 1,000 0,02604312 0,08332414 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 1,000 0,02705995 0,08646246 ! response to temperature stimulus GO:0009266 76 49 1,000 0,02705995 0,08634779 ! histone modification GO:0016570 91 50 1,000 0,0280926 0,08952425 ! positive regulation of cytokine production GO:0001819 86 50 1,000 0,0280926 0,08940583 ! positive regulation of binding GO:0051099 78 51 1,000 0,0291409 0,09261957 ! viral infectious cycle GO:0019058 99 51 1,000 0,0291409 0,09249738 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 1,000 0,0291409 0,09237551 ! covalent chromatin modification GO:0016569 101 52 1,000 0,03020466 0,09562159 ! cartilage development GO:0051216 90 52 1,000 0,03020466 0,09549594 ! synapse organization GO:0050808 85 52 1,000 0,03020466 0,09537061 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03087574 0,09736176 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03087574 0,09723432 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,03087574 0,09710722 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03087574 0,09698045 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03087574 0,09685401 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,03087574 0,09672789 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,03087574 0,09660211 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03087574 0,09647665 ! sleep GO:0030431 13 6 0,000 0,03087574 0,09635152 ! response to oxygen radical GO:0000305 11 6 0,000 0,03087574 0,09622671 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,03087574 0,09610223 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,03087574 0,09597807 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,03087574 0,09585422 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,03087574 0,0957307 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03087574 0,09560749 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03087574 0,0954846 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,03087574 0,09536203 ! forebrain regionalization GO:0021871 8 6 0,000 0,03087574 0,09523977 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03087574 0,09511783 ! male meiosis GO:0007140 7 6 0,000 0,03087574 0,09499619 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03087574 0,09487487 ! response to zinc ion GO:0010043 9 6 0,000 0,03087574 0,09475386 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03087574 0,09463315 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,03087574 0,09451275 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,03087574 0,09439266 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03087574 0,09427287 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03087574 0,09415339 ! malate metabolic process GO:0006108 11 6 0,000 0,03087574 0,09403421 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,03087574 0,09391533 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,03087574 0,09379675 ! protein refolding GO:0042026 15 6 0,000 0,03087574 0,09367846 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03087574 0,09356048 ! opsonization GO:0008228 8 6 0,000 0,03087574 0,0934428 ! mating behavior GO:0007617 7 6 0,000 0,03087574 0,09332541 ! neuron remodeling GO:0016322 15 6 0,000 0,03087574 0,09320831 ! erythrocyte maturation GO:0043249 7 6 0,000 0,03087574 0,09309151 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,03087574 0,092975 ! equilibrioception GO:0050957 14 6 0,000 0,03087574 0,09285878 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,03087574 0,09274285 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,03087574 0,09262721 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03087574 0,09251186 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,03087574 0,09239679 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03087574 0,09228202 ! response to interferon-gamma GO:0034341 15 6 0,000 0,03087574 0,09216752 ! toxin metabolic process GO:0009404 11 6 0,000 0,03087574 0,09205331 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03087574 0,09193938 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03087574 0,09182574 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,03087574 0,09171237 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,03087574 0,09159929 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,03087574 0,09148648 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03087574 0,09137395 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,03087574 0,0912617 ! thymic T cell selection GO:0045061 12 6 0,000 0,03087574 0,09114972 ! protein lipoylation GO:0009249 10 6 0,000 0,03087574 0,09103802 ! cysteine metabolic process GO:0006534 10 6 0,000 0,03087574 0,09092659 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,03087574 0,09081543 ! glutamate catabolic process GO:0006538 10 6 0,000 0,03087574 0,09070455 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,03087574 0,09059393 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! adenohypophysis development GO:0021984 10 6 0,000 0,03087574 0,09048358 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,03087574 0,09037351 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03087574 0,0902637 ! hyperosmotic response GO:0006972 9 6 0,000 0,03087574 0,09015415 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,03087574 0,09004488 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,03087574 0,08993586 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03087574 0,08982711 ! urea metabolic process GO:0019627 7 6 0,000 0,03087574 0,08971863 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03087574 0,0896104 ! neutrophil activation GO:0042119 8 6 0,000 0,03087574 0,08950244 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03087574 0,08939473 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,03087574 0,08928729 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03087574 0,0891801 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03087574 0,08907317 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03087574 0,08896649 ! neuron apoptosis GO:0051402 9 6 0,000 0,03087574 0,08886007 ! nucleoside salvage GO:0043174 9 6 0,000 0,03087574 0,08875391 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,03087574 0,088648 ! T cell mediated immunity GO:0002456 16 6 0,000 0,03087574 0,08854234 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03087574 0,08843693 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,03087574 0,08833177 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,03087574 0,08822687 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03087574 0,08812221 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,03087574 0,0880178 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,03087574 0,08791364 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,03087574 0,08780972 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03087574 0,08770605 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,03087574 0,08760262 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,03087574 0,08749944 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,03087574 0,0873965 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,03087574 0,0872938 ! monocyte differentiation GO:0030224 12 6 0,000 0,03087574 0,08719134 ! neural nucleus development GO:0048857 14 6 0,000 0,03087574 0,08708912 ! response to UV-C GO:0010225 11 6 0,000 0,03087574 0,08698715 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,03087574 0,08688541 ! interaction with symbiont GO:0051702 13 6 0,000 0,03087574 0,0867839 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03087574 0,08668264 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03087574 0,08658161 ! response to copper ion GO:0046688 10 6 0,000 0,03087574 0,08648082 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,03087574 0,08638026 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03087574 0,08627993 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03087574 0,08617984 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,03087574 0,08607998 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03087574 0,08598035 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,03087574 0,08588095 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03087574 0,08578178 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,03087574 0,08568284 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03087574 0,08558413 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,03087574 0,08548564 ! subpallium development GO:0021544 10 6 0,000 0,03087574 0,08538738 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,03087574 0,08528935 ! histone ubiquitination GO:0016574 8 6 0,000 0,03087574 0,08519154 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,03087574 0,08509395 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03087574 0,08499659 ! G2 phase GO:0051319 16 6 0,000 0,03087574 0,08489945 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,03087574 0,08480254 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03087574 0,08470584 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,03087574 0,08460937 ! membrane to membrane docking GO:0022614 14 6 0,000 0,03087574 0,08451311 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03087574 0,08441707 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,03087574 0,08432125 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03087574 0,08422565 ! receptor internalization GO:0031623 10 6 0,000 0,03087574 0,08413026 ! neutrophil homeostasis GO:0001780 10 6 0,000 0,03087574 0,08403509 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03087574 0,08394014 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,03087574 0,0838454 ! protein deubiquitination GO:0016579 14 6 0,000 0,03087574 0,08375087 ! protein destabilization GO:0031648 9 6 0,000 0,03087574 0,08365656 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03087574 0,08356246 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,03087574 0,08346856 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,03087574 0,08337489 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,03087574 0,08328142 ! progesterone metabolic process GO:0042448 10 6 0,000 0,03087574 0,08318816 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,03087574 0,0830951 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,03087574 0,08300226 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,03087574 0,08290962 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,03087574 0,08281719 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03087574 0,08272497 ! determination of adult lifespan GO:0008340 15 6 0,000 0,03087574 0,08263295 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,03087574 0,08254114 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,03087574 0,08244953 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03087574 0,08235812 ! catecholamine transport GO:0051937 9 6 0,000 0,03087574 0,08226691 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,03087574 0,08217591 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03087574 0,08208511 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,03087574 0,08199451 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,03087574 0,0819041 ! maternal placenta development GO:0001893 12 6 0,000 0,03087574 0,0818139 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,03087574 0,0817239 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03087574 0,08163409 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,03087574 0,08154448 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03087574 0,08145507 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,03087574 0,08136585 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,03087574 0,08127683 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 1,000 0,03128368 0,08226069 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 1,000 0,03128368 0,08217088 ! cell maturation GO:0048469 100 53 1,000 0,03128368 0,08208127 ! regulation of protein polymerization GO:0032271 103 53 1,000 0,03128368 0,08199186 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,03237778 0,08476707 GO:0010863|positive regulation of phospholipase C activity, ! glutamine family amino acid metabolic process GO:0009064 78 54 1,000 0,03237778 0,08467493 ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 0,03348677 0,08748011 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,03348677 0,08738522 ! gastrulation GO:0007369 112 55 1,000 0,03348677 0,08729055 ! heart morphogenesis GO:0003007 97 55 1,000 0,03348677 0,08719608 ! regulation of multicellular organism growth GO:0040014 85 55 1,000 0,03348677 0,08710181 ! regulation of actin filament length GO:0030832 105 56 1,000 0,03461048 0,08992745 ! nucleotide-excision repair GO:0006289 83 56 1,000 0,03461048 0,08983044 ! regulation of bone remodeling GO:0046850 137 57 1,000 0,03574872 0,09268473 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,03574872 0,09258496 ! tRNA transcription GO:0009304 14 7 0,000 0,03592879 0,09295126 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,03592879 0,09285142 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,03592879 0,09275179 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03592879 0,09265238 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,03592879 0,09255318 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,03592879 0,09245419 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03592879 0,09235542 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,03592879 0,09225685 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03592879 0,0921585 ! prostate gland development GO:0030850 13 7 0,000 0,03592879 0,09206035 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,03592879 0,09196242 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03592879 0,09186469 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03592879 0,09176717 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,03592879 0,09166985 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03592879 0,09157274 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,03592879 0,09147584 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,03592879 0,09137914 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,03592879 0,09128265 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03592879 0,09118636 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,03592879 0,09109027 ! glycolipid transport GO:0046836 10 7 0,000 0,03592879 0,09099439 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03592879 0,09089871 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,03592879 0,09080323 ! neuron adhesion GO:0007158 12 7 0,000 0,03592879 0,09070794 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03592879 0,09061286 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,03592879 0,09051798 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03592879 0,0904233 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,03592879 0,09032881 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,03592879 0,09023452 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,03592879 0,09014043 ! mRNA stabilization GO:0048255 18 7 0,000 0,03592879 0,09004653 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,03592879 0,08995283 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,03592879 0,08985932 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,03592879 0,08976601 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,03592879 0,08967289 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,03592879 0,08957997 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,03592879 0,08948724 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03592879 0,0893947 ! lipoprotein transport GO:0042953 14 7 0,000 0,03592879 0,08930235 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,03592879 0,08921019 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,03592879 0,08911822 ! rhythmic behavior GO:0007622 15 7 0,000 0,03592879 0,08902644 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,03592879 0,08893485 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,03592879 0,08884344 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,03592879 0,08875223 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03592879 0,0886612 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,03592879 0,08857036 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03592879 0,0884797 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,03592879 0,08838923 ! mechanosensory behavior GO:0007638 14 7 0,000 0,03592879 0,08829895 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,03592879 0,08820885 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,03592879 0,08811893 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,03592879 0,0880292 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03592879 0,08793964 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03592879 0,08785027 ! spinal cord patterning GO:0021511 13 7 0,000 0,03592879 0,08776109 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,03592879 0,08767208 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03592879 0,08758325 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,03592879 0,08749461 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,03592879 0,08740614 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,03592879 0,08731785 ! ovulation GO:0030728 9 7 0,000 0,03592879 0,08722974 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,03592879 0,08714181 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,03592879 0,08705405 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,03592879 0,08696647 ! microtubule nucleation GO:0007020 20 7 0,000 0,03592879 0,08687907 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03592879 0,08679184 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03592879 0,08670478 ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,03592879 0,08661791 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,03592879 0,0865312 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03592879 0,08644467 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,03592879 0,08635831 ! galactose metabolic process GO:0006012 13 7 0,000 0,03592879 0,08627213 ! vesicle fusion GO:0006906 17 7 0,000 0,03592879 0,08618611 ! response to dietary excess GO:0002021 8 7 0,000 0,03592879 0,08610027 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03592879 0,0860146 ! intracellular pH reduction GO:0051452 11 7 0,000 0,03592879 0,0859291 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03592879 0,08584376 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,03592879 0,0857586 ! organ growth GO:0035265 15 7 0,000 0,03592879 0,08567361 ! purine salvage GO:0043101 10 7 0,000 0,03592879 0,08558878 ! nucleoside transport GO:0015858 8 7 0,000 0,03592879 0,08550413 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,03592879 0,08541963 ! parturition GO:0007567 14 7 0,000 0,03592879 0,08533531 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,03592879 0,08525115 ! rRNA modification GO:0000154 14 7 0,000 0,03592879 0,08516716 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,03592879 0,08508334 ! spindle checkpoint GO:0031577 15 7 0,000 0,03592879 0,08499968 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,03592879 0,08491618 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,03592879 0,08483285 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,03592879 0,08474968 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03592879 0,08466667 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,03592879 0,08458383 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,03592879 0,08450114 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03592879 0,08441862 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,03592879 0,08433626 ! eating behavior GO:0042755 7 7 0,000 0,03592879 0,08425406 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03592879 0,08417203 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,03592879 0,08409015 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,03592879 0,08400843 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03592879 0,08392686 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03592879 0,08384546 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,03592879 0,08376422 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,03592879 0,08368313 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,03592879 0,0836022 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,03592879 0,08352142 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03592879 0,0834408 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,03592879 0,08336034 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03592879 0,08328003 ! regulation of meiosis GO:0040020 12 7 0,000 0,03592879 0,08319988 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,03592879 0,08311988 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,03592879 0,08304003 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03592879 0,08296034 ! oxygen homeostasis GO:0032364 12 7 0,000 0,03592879 0,0828808 ! transcription termination GO:0006353 13 7 0,000 0,03592879 0,08280141 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03592879 0,08272217 ! anaphase GO:0051322 17 7 0,000 0,03592879 0,08264309 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,03592879 0,08256416 ! axonal fasciculation GO:0007413 18 7 0,000 0,03592879 0,08248537 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,03592879 0,08240674 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,03592879 0,08232826 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,03592879 0,08224992 ! diuresis GO:0030146 12 7 0,000 0,03592879 0,08217174 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03592879 0,0820937 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03592879 0,08201582 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03592879 0,08193808 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,03592879 0,08186048 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,03592879 0,08178304 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03592879 0,08170574 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,03592879 0,08162858 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,03592879 0,08155158 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,03592879 0,08147471 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,03592879 0,08139799 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03592879 0,08132142 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,03592879 0,08124499 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03592879 0,0811687 ! lymph node development GO:0048535 10 7 0,000 0,03592879 0,08109256 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,03592879 0,08101656 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,03592879 0,0809407 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,03592879 0,08086499 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,03592879 0,08078941 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,03592879 0,08071398 ! adult feeding behavior GO:0008343 9 7 0,000 0,03592879 0,08063869 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,03592879 0,08056353 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,03592879 0,08048852 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03592879 0,08041365 ! muscle adaptation GO:0043500 14 7 0,000 0,03592879 0,08033891 ! embryonic heart tube development GO:0035050 10 7 0,000 0,03592879 0,08026432 ! retina homeostasis GO:0001895 12 7 0,000 0,03592879 0,08018986 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,03592879 0,08011554 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,03592879 0,08004136 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,03592879 0,07996732 ! protein prenylation GO:0018342 18 7 0,000 0,03592879 0,07989341 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,03592879 0,07981964 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,03592879 0,07974601 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,03592879 0,07967251 ! regulation of tissue remodeling GO:0034103 140 58 1,000 0,03690132 0,08175374 ! regulation of endocytosis GO:0030100 91 58 1,000 0,03690132 0,08167853 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,03690132 0,08160346 ! regulation of cellular component size GO:0032535 109 59 1,000 0,03806808 0,08410634 ! DNA catabolic process GO:0006308 86 59 1,000 0,03806808 0,08402918 ! camera-type eye development GO:0043010 116 60 1,000 0,03924884 0,08655611 ! mesoderm development GO:0007498 119 61 1,000 0,04044343 0,08910887 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,04095566 0,09015492 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,04095566 0,09007251 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,04095566 0,08999026 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,04095566 0,08990815 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,04095566 0,08982619 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04095566 0,08974438 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04095566 0,08966272 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,04095566 0,08958121 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,04095566 0,08949985 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,04095566 0,08941863 ! meiotic prophase I GO:0007128 13 8 0,000 0,04095566 0,08933756 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04095566 0,08925664 ! oligopeptide transport GO:0006857 15 8 0,000 0,04095566 0,08917586 ! UTP metabolic process GO:0046051 8 8 0,000 0,04095566 0,08909523 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,04095566 0,08901475 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,04095566 0,08893441 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,04095566 0,08885422 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04095566 0,08877417 ! succinate metabolic process GO:0006105 14 8 0,000 0,04095566 0,08869427 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,04095566 0,08861451 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,04095566 0,08853489 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,04095566 0,08845541 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,04095566 0,08837608 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,04095566 0,08829689 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04095566 0,08821784 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04095566 0,08813894 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,04095566 0,08806017 ! reflex GO:0060004 16 8 0,000 0,04095566 0,08798154 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,04095566 0,08790306 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,04095566 0,08782471 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04095566 0,08774651 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,04095566 0,08766844 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,04095566 0,08759052 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,04095566 0,08751273 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,04095566 0,08743508 ! pigment granule organization GO:0048753 16 8 0,000 0,04095566 0,08735756 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,04095566 0,08728019 ! histidine metabolic process GO:0006547 16 8 0,000 0,04095566 0,08720295 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04095566 0,08712584 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,04095566 0,08704888 ! glycine catabolic process GO:0006546 13 8 0,000 0,04095566 0,08697205 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,04095566 0,08689535 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,04095566 0,08681879 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,04095566 0,08674237 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,04095566 0,08666608 ! melanin metabolic process GO:0006582 15 8 0,000 0,04095566 0,08658992 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,04095566 0,0865139 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,04095566 0,08643801 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,04095566 0,08636225 ! macrophage activation GO:0042116 12 8 0,000 0,04095566 0,08628663 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,04095566 0,08621114 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,04095566 0,08613578 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,04095566 0,08606055 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,04095566 0,08598545 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,04095566 0,08591049 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,04095566 0,08583565 ! osteoblast development GO:0002076 16 8 0,000 0,04095566 0,08576095 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,04095566 0,08568637 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,04095566 0,08561193 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,04095566 0,08553761 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,04095566 0,08546343 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04095566 0,08538937 ! response to UV-B GO:0010224 16 8 0,000 0,04095566 0,08531544 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,04095566 0,08524163 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04095566 0,08516796 ! intermediate filament organization GO:0045109 12 8 0,000 0,04095566 0,08509441 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,04095566 0,08502099 ! cellular extravasation GO:0045123 12 8 0,000 0,04095566 0,0849477 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,04095566 0,08487453 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,04095566 0,08480149 ! response to antibiotic GO:0046677 11 8 0,000 0,04095566 0,08472857 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,04095566 0,08465578 ! DNA topological change GO:0006265 12 8 0,000 0,04095566 0,08458312 ! response to tropane GO:0014073 15 8 0,000 0,04095566 0,08451057 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,04095566 0,08443816 ! melanosome transport GO:0032402 13 8 0,000 0,04095566 0,08436586 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,04095566 0,0842937 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04095566 0,08422165 ! mast cell activation GO:0045576 14 8 0,000 0,04095566 0,08414973 ! multicellular organismal aging GO:0010259 18 8 0,000 0,04095566 0,08407793 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,04095566 0,08400625 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,04095566 0,08393469 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04095566 0,08386326 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04095566 0,08379195 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,04095566 0,08372076 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04095566 0,08364969 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,04095566 0,08357874 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,04095566 0,08350791 ! intracellular lipid transport GO:0032365 13 8 0,000 0,04095566 0,0834372 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04095566 0,08336661 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,04095566 0,08329614 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,04095566 0,08322579 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,04095566 0,08315555 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,04095566 0,08308544 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,04095566 0,08301544 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,04095566 0,08294556 ! hormone catabolic process GO:0042447 17 8 0,000 0,04095566 0,0828758 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04095566 0,08280616 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,04095566 0,08273663 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,04095566 0,08266722 ! ATP catabolic process GO:0006200 11 8 0,000 0,04095566 0,08259793 ! blastocyst growth GO:0001832 19 8 0,000 0,04095566 0,08252875 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,04095566 0,08245969 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04095566 0,08239074 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,04095566 0,08232191 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04095566 0,0822532 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,04095566 0,0821846 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,04095566 0,08211611 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,04095566 0,08204773 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,04095566 0,08197948 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,04095566 0,08191133 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,04095566 0,0818433 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,04095566 0,08177538 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04095566 0,08170757 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,04095566 0,08163988 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04095566 0,08157229 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,04095566 0,08150482 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,04095566 0,08143746 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,04095566 0,08137021 ! regulation of homeostatic process GO:0032844 134 62 1,000 0,04165166 0,08268472 ! nucleoside monophosphate metabolic process GO:0009123 107 63 1,000 0,04287336 0,08503982 ! steroid hormone receptor signaling pathway GO:0030518 129 63 1,000 0,04287336 0,08496977 ! single fertilization GO:0007338 75 64 1,000 0,04410836 0,08734545 ! germ cell development GO:0007281 118 65 1,000 0,0453565 0,08974321 ! axon extension GO:0048675 15 9 0,000 0,04595649 0,09085565 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,04595649 0,09078105 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,04595649 0,09070658 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,04595649 0,09063223 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,04595649 0,09055801 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,04595649 0,0904839 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,04595649 0,09040991 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,04595649 0,09033605 ! phosphate transport GO:0006817 19 9 0,000 0,04595649 0,09026231 ! reproductive behavior GO:0019098 19 9 0,000 0,04595649 0,09018868 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,04595649 0,09011518 ! CTP metabolic process GO:0046036 9 9 0,000 0,04595649 0,0900418 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,04595649 0,08996853 ! GTP metabolic process GO:0046039 9 9 0,000 0,04595649 0,08989539 ! RNA methylation GO:0001510 15 9 0,000 0,04595649 0,08982236 ! elastic fiber assembly GO:0048251 15 9 0,000 0,04595649 0,08974945 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,04595649 0,08967666 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,04595649 0,08960399 ! regulation of histone modification GO:0031056 12 9 0,000 0,04595649 0,08953144 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,04595649 0,089459 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,04595649 0,08938668 ! chemosensory behavior GO:0007635 20 9 0,000 0,04595649 0,08931448 ! microtubule bundle formation GO:0001578 21 9 0,000 0,04595649 0,08924239 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,04595649 0,08917042 ! leukocyte degranulation GO:0043299 16 9 0,000 0,04595649 0,08909857 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,04595649 0,08902683 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,04595649 0,08895521 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,04595649 0,0888837 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,04595649 0,08881231 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,04595649 0,08874103 ! protein targeting to ER GO:0045047 22 9 0,000 0,04595649 0,08866987 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,04595649 0,08859882 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,04595649 0,08852788 ! T cell selection GO:0045058 23 9 0,000 0,04595649 0,08845706 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,04595649 0,08838635 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,04595649 0,08831575 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,04595649 0,08824527 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,04595649 0,0881749 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,04595649 0,08810464 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,04595649 0,08803449 ! mannose metabolic process GO:0006013 13 9 0,000 0,04595649 0,08796446 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,04595649 0,08789453 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,04595649 0,08782472 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,04595649 0,08775502 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,04595649 0,08768543 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,04595649 0,08761595 ! ruffle organization GO:0031529 15 9 0,000 0,04595649 0,08754658 ! retinol metabolic process GO:0042572 18 9 0,000 0,04595649 0,08747731 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,04595649 0,08740816 ! behavioral fear response GO:0001662 22 9 0,000 0,04595649 0,08733912 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,04595649 0,08727018 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,04595649 0,08720136 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,04595649 0,08713264 GO:0030204|chondroitin sulfate metabolic process, ! oligodendrocyte development GO:0014003 10 9 0,000 0,04595649 0,08706403 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,04595649 0,08699553 ! segment specification GO:0007379 13 9 0,000 0,04595649 0,08692714 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,04595649 0,08685886 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,04595649 0,08679068 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,04595649 0,08672261 ! response to amine stimulus GO:0014075 13 9 0,000 0,04595649 0,08665464 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,04595649 0,08658678 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,04595649 0,08651903 ! erythrocyte development GO:0048821 15 9 0,000 0,04595649 0,08645139 ! gas homeostasis GO:0033483 16 9 0,000 0,04595649 0,08638385 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,04595649 0,08631641 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,04595649 0,08624908 ! renal water homeostasis GO:0003091 14 9 0,000 0,04595649 0,08618186 ! postreplication repair GO:0006301 22 9 0,000 0,04595649 0,08611474 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,04595649 0,08604772 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,04595649 0,08598081 ! icosanoid secretion GO:0032309 15 9 0,000 0,04595649 0,085914 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,04595649 0,0858473 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,04595649 0,0857807 ! regulation of cell division GO:0051302 15 9 0,000 0,04595649 0,0857142 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,04595649 0,08564781 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,04595649 0,08558152 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,04595649 0,08551533 ! sterol catabolic process GO:0016127 11 9 0,000 0,04595649 0,08544925 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,04595649 0,08538326 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,04595649 0,08531738 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,04595649 0,0852516 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,04595649 0,08518592 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,04595649 0,08512034 ! musculoskeletal movement GO:0050881 14 9 0,000 0,04595649 0,08505486 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,04595649 0,08498949 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,04595649 0,08492421 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,04595649 0,08485904 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,04595649 0,08479396 ! pigment granule transport GO:0051904 17 9 0,000 0,04595649 0,08472898 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,04595649 0,08466411 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,04595649 0,08459933 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,04595649 0,08453465 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,04595649 0,08447007 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,04595649 0,08440559 ! mitochondrion localization GO:0051646 15 9 0,000 0,04595649 0,08434121 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 1,000 0,0466176 0,0854893 ! extracellular matrix organization GO:0030198 133 66 1,000 0,0466176 0,08542419 ! regulation of cellular response to stress GO:0080135 128 67 1,000 0,0478915 0,08769175 ! chromosome segregation GO:0007059 113 67 1,000 0,0478915 0,08762506 ! positive regulation of T cell activation GO:0050870 109 67 1,000 0,0478915 0,08755848 ! negative regulation of ligase activity GO:0051352 112 68 1,000 0,04917803 0,08984233 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 1,000 0,04917803 0,08977416 ! regulation of lipase activity GO:0060191 130 68 1,000 0,04917803 0,0897061 ! cAMP-mediated signaling GO:0019933 120 69 1,000 0,05047703 0,09200586 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,05093141 0,0927638 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,05093141 0,09269363 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,05093141 0,09262357 ! synapsis GO:0007129 13 10 0,000 0,05093141 0,09255361 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,05093141 0,09248376 ! N-glycan processing GO:0006491 20 10 0,000 0,05093141 0,09241401 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,05093141 0,09234437 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,05093141 0,09227483 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,05093141 0,0922054 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,05093141 0,09213607 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,05093141 0,09206685 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,05093141 0,09199773 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,05093141 0,09192871 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,05093141 0,0918598 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,05093141 0,09179099 ! androgen metabolic process GO:0008209 17 10 0,000 0,05093141 0,09172229 ! phospholipid efflux GO:0033700 16 10 0,000 0,05093141 0,09165369 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,05093141 0,09158518 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,05093141 0,09151679 ! lung alveolus development GO:0048286 26 10 0,000 0,05093141 0,09144849 ! pathogenesis GO:0009405 13 10 0,000 0,05093141 0,0913803 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,05093141 0,0913122 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,05093141 0,09124421 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,05093141 0,09117632 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,05093141 0,09110853 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,05093141 0,09104084 ! endoderm development GO:0007492 16 10 0,000 0,05093141 0,09097326 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,05093141 0,09090577 ! arginine catabolic process GO:0006527 13 10 0,000 0,05093141 0,09083838 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,05093141 0,09077109 ! proline metabolic process GO:0006560 13 10 0,000 0,05093141 0,09070391 ! L-serine metabolic process GO:0006563 18 10 0,000 0,05093141 0,09063682 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,05093141 0,09056983 ! V(D)J recombination GO:0033151 28 10 0,000 0,05093141 0,09050294 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,05093141 0,09043615 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,05093141 0,09036945 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,05093141 0,09030286 ! B cell proliferation GO:0042100 18 10 0,000 0,05093141 0,09023636 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,05093141 0,09016996 ! multicellular organism growth GO:0035264 18 10 0,000 0,05093141 0,09010366 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,05093141 0,09003746 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,05093141 0,08997135 ! epithelial cell development GO:0002064 20 10 0,000 0,05093141 0,08990534 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,05093141 0,08983943 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,05093141 0,08977361 ! macroautophagy GO:0016236 17 10 0,000 0,05093141 0,08970789 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,05093141 0,08964227 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,05093141 0,08957674 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,05093141 0,08951131 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,05093141 0,08944597 ! copper ion homeostasis GO:0055070 13 10 0,000 0,05093141 0,08938073 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,05093141 0,08931558 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,05093141 0,08925053 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,05093141 0,08918557 ! blastoderm segmentation GO:0007350 18 10 0,000 0,05093141 0,08912071 ! response to dsRNA GO:0043331 20 10 0,000 0,05093141 0,08905594 ! DNA ligation GO:0006266 19 10 0,000 0,05093141 0,08899127 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,05093141 0,08892669 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,05093141 0,0888622 ! melanosome localization GO:0032400 16 10 0,000 0,05093141 0,08879781 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,05093141 0,08873351 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,05093141 0,0886693 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,05093141 0,08860519 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,05093141 0,08854117 ! mRNA cleavage GO:0006379 17 10 0,000 0,05093141 0,08847724 ! protein sumoylation GO:0016925 15 10 0,000 0,05093141 0,0884134 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,05093141 0,08834966 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,05093141 0,08828601 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,05093141 0,08822245 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,05093141 0,08815898 ! salivary gland development GO:0007431 27 10 0,000 0,05093141 0,0880956 ! prophase GO:0051324 15 10 0,000 0,05093141 0,08803231 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,05093141 0,08796911 ! apical protein localization GO:0045176 15 10 0,000 0,05093141 0,08790601 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,05093141 0,08784299 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,05093141 0,08778007 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,05093141 0,08771723 ! midbrain development GO:0030901 13 10 0,000 0,05093141 0,08765449 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,05093141 0,08759183 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,05093141 0,08752927 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,05093141 0,08746679 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,05093141 0,08740441 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,05093141 0,08734211 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,05093141 0,0872799 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,05093141 0,08721778 ! detection of calcium ion GO:0005513 23 10 0,000 0,05093141 0,08715574 ! oocyte development GO:0048599 17 10 0,000 0,05093141 0,0870938 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,05093141 0,08703194 ! blastocyst formation GO:0001825 17 10 0,000 0,05093141 0,08697018 ! cerebellar cortex development GO:0021695 15 10 0,000 0,05093141 0,08690849 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,05093141 0,0868469 ! activation of innate immune response GO:0002218 12 10 0,000 0,05093141 0,08678539 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,05093141 0,08672398 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,05093141 0,08666264 ! response to nicotine GO:0035094 20 10 0,000 0,05093141 0,0866014 ! establishment of cell polarity GO:0030010 16 10 0,000 0,05093141 0,08654024 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,05093141 0,08647917 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,05093141 0,08641818 ! B cell activation GO:0042113 160 71 1,000 0,05311177 0,09005421 ! regulation of immune effector process GO:0002697 137 71 1,000 0,05311177 0,08999079 ! carbohydrate transport GO:0008643 110 72 1,000 0,0544472 0,09218857 ! learning or memory GO:0007611 147 73 1,000 0,05579444 0,09440325 ! axon guidance GO:0007411 139 73 1,000 0,05579444 0,09433691 ! fertilization GO:0009566 90 73 1,000 0,05579444 0,09427067 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,05588055 0,0943499 ! respiratory burst GO:0045730 17 11 0,000 0,05588055 0,09428374 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,05588055 0,09421767 ! neuron fate specification GO:0048665 17 11 0,000 0,05588055 0,09415169 ! telencephalon cell migration GO:0022029 20 11 0,000 0,05588055 0,0940858 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,05588055 0,09402001 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,05588055 0,0939543 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,05588055 0,09388869 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,05588055 0,09382317 ! response to pain GO:0048265 24 11 0,000 0,05588055 0,09375775 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,05588055 0,09369241 ! T cell proliferation GO:0042098 26 11 0,000 0,05588055 0,09362716 ! blood vessel remodeling GO:0001974 29 11 0,000 0,05588055 0,09356201 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,05588055 0,09349695 ! bone resorption GO:0045453 16 11 0,000 0,05588055 0,09343197 ! ventral spinal cord development GO:0021517 21 11 0,000 0,05588055 0,09336709 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,05588055 0,0933023 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,05588055 0,09323759 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,05588055 0,09317298 ! melanocyte differentiation GO:0030318 21 11 0,000 0,05588055 0,09310845 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,05588055 0,09304402 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,05588055 0,09297967 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,05588055 0,09291542 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! lipid digestion GO:0044241 18 11 0,000 0,05588055 0,09285125 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,05588055 0,09278717 ! UV protection GO:0009650 19 11 0,000 0,05588055 0,09272318 ! adult heart development GO:0007512 14 11 0,000 0,05588055 0,09265928 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,05588055 0,09259546 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,05588055 0,09253173 ! temperature homeostasis GO:0001659 17 11 0,000 0,05588055 0,09246809 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,05588055 0,09240454 ! negative regulation of ossification GO:0030279 26 11 0,000 0,05588055 0,09234108 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,05588055 0,0922777 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,05588055 0,09221441 ! regulation of organ growth GO:0046620 13 11 0,000 0,05588055 0,09215121 ! pigment granule localization GO:0051875 20 11 0,000 0,05588055 0,09208809 ! vasoconstriction GO:0042310 18 11 0,000 0,05588055 0,09202506 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,05588055 0,09196211 ! embryonic axis specification GO:0000578 18 11 0,000 0,05588055 0,09189925 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,05588055 0,09183648 ! snRNA metabolic process GO:0016073 24 11 0,000 0,05588055 0,09177379 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,05588055 0,09171119 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,05588055 0,09164868 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,05588055 0,09158625 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,05588055 0,0915239 ! zymogen activation GO:0031638 15 11 0,000 0,05588055 0,09146164 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,05588055 0,09139946 ! nucleosome positioning GO:0016584 15 11 0,000 0,05588055 0,09133737 ! regulation of isotype switching GO:0045191 22 11 0,000 0,05588055 0,09127536 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,05588055 0,09121344 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,05588055 0,0911516 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,05588055 0,09108984 ! acid secretion GO:0046717 18 11 0,000 0,05588055 0,09102817 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,05588055 0,09096658 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,05588055 0,09090508 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,05588055 0,09084365 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,05588055 0,09078232 ! oocyte differentiation GO:0009994 18 11 0,000 0,05588055 0,09072106 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,05588055 0,09065988 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 19 11 0,000 0,05588055 0,09059879 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,05588055 0,09053778 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,05588055 0,09047686 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,05588055 0,09041601 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,05588055 0,09035525 ! embryonic gut development GO:0048566 15 11 0,000 0,05588055 0,09029457 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,05588055 0,09023397 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,05588055 0,09017345 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,05588055 0,09011301 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,05588055 0,09005265 ! defense response to fungus GO:0050832 13 11 0,000 0,05588055 0,08999238 ! lysogeny GO:0030069 21 11 0,000 0,05588055 0,08993218 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,05588055 0,08987206 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,05588055 0,08981203 ! sequestering of metal ion GO:0051238 14 11 0,000 0,05588055 0,08975208 ! lamellipodium assembly GO:0030032 20 11 0,000 0,05588055 0,0896922 ! regulation of synapse organization GO:0050807 17 11 0,000 0,05588055 0,08963241 ! regulation of actin cytoskeleton organization GO:0032956 149 74 1,000 0,05715335 0,0916129 ! eye development GO:0001654 143 74 1,000 0,05715335 0,09155191 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,05852377 0,09368476 ! regulation of vesicle-mediated transport GO:0060627 119 75 1,000 0,05852377 0,09362247 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,05852377 0,09356026 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,06080405 0,09714113 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,06080405 0,09707667 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,06080405 0,09701229 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,06080405 0,096948 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,06080405 0,0968838 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,06080405 0,09681968 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,06080405 0,09675565 ! protein complex disassembly GO:0043241 27 12 0,000 0,06080405 0,0966917 GO:0043624|cellular protein complex disassembly, ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,06080405 0,09662783 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,06080405 0,09656405 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,06080405 0,09650036 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,06080405 0,09643674 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,06080405 0,09637321 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,06080405 0,09630977 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,06080405 0,09624641 ! drug transport GO:0015893 16 12 0,000 0,06080405 0,09618313 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,06080405 0,09611993 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,06080405 0,09605682 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,06080405 0,09599379 ! polyamine metabolic process GO:0006595 17 12 0,000 0,06080405 0,09593085 ! mitotic spindle organization GO:0007052 21 12 0,000 0,06080405 0,09586798 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,06080405 0,0958052 ! forebrain cell migration GO:0021885 21 12 0,000 0,06080405 0,0957425 ! asymmetric protein localization GO:0008105 20 12 0,000 0,06080405 0,09567988 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,06080405 0,09561735 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,06080405 0,09555489 ! fear response GO:0042596 26 12 0,000 0,06080405 0,09549252 ! monoamine transport GO:0015844 18 12 0,000 0,06080405 0,09543023 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06080405 0,09536802 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,06080405 0,09530589 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,06080405 0,09524384 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,06080405 0,09518187 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,06080405 0,09511999 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,06080405 0,09505818 ! protein homotetramerization GO:0051289 21 12 0,000 0,06080405 0,09499645 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,06080405 0,09493481 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,06080405 0,09487324 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,06080405 0,09481176 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,06080405 0,09475035 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,06080405 0,09468902 ! fucose catabolic process GO:0019317 22 12 0,000 0,06080405 0,09462777 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,06080405 0,09456661 ! histone methylation GO:0016571 26 12 0,000 0,06080405 0,09450552 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,06080405 0,09444451 ! gland morphogenesis GO:0022612 29 12 0,000 0,06080405 0,09438357 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,06080405 0,09432272 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,06080405 0,09426194 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,06080405 0,09420125 ! spleen development GO:0048536 22 12 0,000 0,06080405 0,09414063 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,06080405 0,09408009 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,06080405 0,09401963 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,06080405 0,09395924 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,06080405 0,09389893 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,06080405 0,0938387 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,06080405 0,09377855 ! response to cold GO:0009409 17 12 0,000 0,06080405 0,09371847 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,06080405 0,09365848 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,06080405 0,09359855 ! regulation of actin filament-based process GO:0032970 152 77 1,000 0,06129851 0,09429938 ! blood coagulation GO:0007596 146 78 1,000 0,06270253 0,09639763 GO:0050817|coagulation, ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,06270253 0,09633607 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 1,000 0,06411744 0,09844708 ! muscle cell differentiation GO:0042692 159 80 1,000 0,0655431 0,10057188 ! cGMP metabolic process GO:0046068 18 13 0,000 0,06570203 0,10075149 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,06570203 0,10068732 ! regulation of chemokine production GO:0032642 18 13 0,000 0,06570203 0,10062322 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,06570203 0,10055921 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,06570203 0,10049529 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,06570203 0,10043144 ! lipid localization GO:0010876 28 13 0,000 0,06570203 0,10036767 GO:0019915|lipid storage, ! organelle fusion GO:0048284 32 13 0,000 0,06570203 0,10030399 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,06570203 0,10024038 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,06570203 0,10017686 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,06570203 0,10011342 ! endocrine pancreas development GO:0031018 22 13 0,000 0,06570203 0,10005005 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,06570203 0,09998677 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,06570203 0,09992357 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,06570203 0,09986045 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,06570203 0,0997974 ! methionine metabolic process GO:0006555 27 13 0,000 0,06570203 0,09973444 ! plasma membrane organization GO:0007009 24 13 0,000 0,06570203 0,09967155 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,06570203 0,09960875 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,06570203 0,09954602 ! Golgi organization GO:0007030 24 13 0,000 0,06570203 0,09948338 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,06570203 0,09942081 ! cytokine metabolic process GO:0042107 22 13 0,000 0,06570203 0,09935832 ! exocrine system development GO:0035272 32 13 0,000 0,06570203 0,09929591 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,06570203 0,09923357 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,06570203 0,09917132 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,06570203 0,09910914 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,06570203 0,09904705 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,06570203 0,09898502 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,06570203 0,09892308 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,06570203 0,09886122 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,06570203 0,09879943 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,06570203 0,09873772 ! ribosome assembly GO:0042255 17 13 0,000 0,06570203 0,09867608 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,06570203 0,09861453 ! chromatin silencing GO:0006342 26 13 0,000 0,06570203 0,09855305 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,06570203 0,09849164 ! regulation of epidermis development GO:0045682 19 13 0,000 0,06570203 0,09843031 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,06570203 0,09836906 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,06570203 0,09830789 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,06570203 0,09824679 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,06570203 0,09818577 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,06570203 0,09812482 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,06570203 0,09806395 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,06570203 0,09800315 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,06570203 0,09794243 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,06570203 0,09788179 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,06570203 0,09782122 ! insulin secretion GO:0030073 23 13 0,000 0,06570203 0,09776072 ! actin filament polymerization GO:0030041 24 13 0,000 0,06570203 0,0977003 ! acrosome reaction GO:0007340 18 13 0,000 0,06570203 0,09763995 ! T cell activation GO:0042110 168 81 1,000 0,06697936 0,09947675 ! digestion GO:0007586 112 81 1,000 0,06697936 0,09941538 ! response to drug GO:0042493 143 82 1,000 0,06842606 0,10150006 ! rRNA transcription GO:0009303 25 14 0,000 0,07057463 0,10462265 ! lactation GO:0007595 26 14 0,000 0,07057463 0,10455823 ! reproductive cellular process GO:0048610 20 14 0,000 0,07057463 0,10449388 ! tRNA modification GO:0006400 20 14 0,000 0,07057463 0,10442962 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,07057463 0,10436543 ! regulation of S phase GO:0033261 23 14 0,000 0,07057463 0,10430133 ! water transport GO:0006833 21 14 0,000 0,07057463 0,1042373 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,07057463 0,10417335 ! non-recombinational repair GO:0000726 25 14 0,000 0,07057463 0,10410948 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,07057463 0,10404569 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,07057463 0,10398197 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,07057463 0,10391834 ! RNA polyadenylation GO:0043631 30 14 0,000 0,07057463 0,10385478 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,07057463 0,1037913 ! palate development GO:0060021 31 14 0,000 0,07057463 0,10372789 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,07057463 0,10366457 ! regulated secretory pathway GO:0045055 23 14 0,000 0,07057463 0,10360132 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,07057463 0,10353815 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,07057463 0,10347505 ! arginine metabolic process GO:0006525 17 14 0,000 0,07057463 0,10341204 ! regulation of heart rate GO:0002027 24 14 0,000 0,07057463 0,10334909 ! organic alcohol transport GO:0015850 29 14 0,000 0,07057463 0,10328623 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,07057463 0,10322344 ! embryo implantation GO:0007566 30 14 0,000 0,07057463 0,10316073 ! neutral amino acid transport GO:0015804 26 14 0,000 0,07057463 0,1030981 ! L-amino acid transport GO:0015807 30 14 0,000 0,07057463 0,10303554 ! bone mineralization GO:0030282 17 14 0,000 0,07057463 0,10297305 ! stem cell development GO:0048864 43 14 0,000 0,07057463 0,10291064 GO:0019827|stem cell maintenance, ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,07057463 0,10284831 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,07057463 0,10278605 ! cerebellum development GO:0021549 21 14 0,000 0,07057463 0,10272387 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,07057463 0,10266177 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,07057463 0,10259974 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,07057463 0,10253778 ! cofactor transport GO:0051181 26 14 0,000 0,07057463 0,1024759 ! NADP metabolic process GO:0006739 24 14 0,000 0,07057463 0,10241409 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,07057463 0,10235236 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,07057463 0,1022907 ! intestinal absorption GO:0050892 25 14 0,000 0,07057463 0,10222912 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,07057463 0,10216761 ! oxygen transport GO:0015671 21 14 0,000 0,07057463 0,10210617 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,07057463 0,10204481 ! male genitalia development GO:0030539 24 14 0,000 0,07057463 0,10198352 ! regulation of RNA stability GO:0043487 32 14 0,000 0,07057463 0,10192231 ! regulation of axon extension GO:0030516 37 14 0,000 0,07057463 0,10186117 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,07057463 0,1018001 ! hemostasis GO:0007599 158 84 1,000 0,07135023 0,10285719 ! regulation of ligase activity GO:0051340 142 84 1,000 0,07135023 0,1027956 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,07542198 0,10859682 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,07542198 0,10853187 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,07542198 0,108467 ! superoxide anion generation GO:0042554 20 15 0,000 0,07542198 0,1084022 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,07542198 0,10833748 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,07542198 0,10827284 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,07542198 0,10820828 ! copper ion transport GO:0006825 20 15 0,000 0,07542198 0,10814379 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,07542198 0,10807938 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,07542198 0,10801505 ! sulfate transport GO:0008272 23 15 0,000 0,07542198 0,1079508 ! response to cAMP GO:0051591 22 15 0,000 0,07542198 0,10788662 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,07542198 0,10782251 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,07542198 0,10775848 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,07542198 0,10769453 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,07542198 0,10763066 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,07542198 0,10756686 ! response to hexose stimulus GO:0009746 22 15 0,000 0,07542198 0,10750313 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,07542198 0,10743948 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,07542198 0,10737591 ! vesicle coating GO:0006901 33 15 0,000 0,07542198 0,10731241 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,07542198 0,10724899 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,07542198 0,10718564 ! regulation of exocytosis GO:0017157 22 15 0,000 0,07542198 0,10712237 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,07542198 0,10705917 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,07542198 0,10699604 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,07542198 0,10693299 ! regulation of vasodilation GO:0042312 26 15 0,000 0,07542198 0,10687002 ! histone deacetylation GO:0016575 20 15 0,000 0,07542198 0,10680711 ! mRNA splice site selection GO:0006376 38 15 0,000 0,07542198 0,10674429 ! tissue regeneration GO:0042246 26 15 0,000 0,07542198 0,10668153 ! water homeostasis GO:0030104 27 15 0,000 0,07542198 0,10661885 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,07542198 0,10655625 ! muscle maintenance GO:0046716 26 15 0,000 0,07542198 0,10649371 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,07542198 0,10643125 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,07542198 0,10636887 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,07542198 0,10630655 ! dopamine metabolic process GO:0042417 35 15 0,000 0,07542198 0,10624431 ! heme biosynthetic process GO:0006783 29 15 0,000 0,07542198 0,10618215 ! cell killing GO:0001906 29 15 0,000 0,07542198 0,10612005 ! detection of bacterium GO:0016045 18 15 0,000 0,07542198 0,10605803 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,07542198 0,10599608 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,07542198 0,1059342 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,07542198 0,1058724 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,07542198 0,10581066 ! peptide hormone processing GO:0016486 23 15 0,000 0,07542198 0,105749 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,08024421 0,11244471 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,08024421 0,11237926 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,08024421 0,11231389 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,08024421 0,11224859 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,08024421 0,11218337 ! bone remodeling GO:0046849 27 16 0,000 0,08024421 0,11211822 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,08024421 0,11205315 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,08024421 0,11198815 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,08024421 0,11192323 ! startle response GO:0001964 28 16 0,000 0,08024421 0,11185838 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,08024421 0,11179361 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,08024421 0,11172892 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,08024421 0,1116643 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,08024421 0,11159975 ! protein polyubiquitination GO:0000209 34 16 0,000 0,08024421 0,11153528 ! glutamate metabolic process GO:0006536 22 16 0,000 0,08024421 0,11147088 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,08024421 0,11140656 ! response to osmotic stress GO:0006970 25 16 0,000 0,08024421 0,11134231 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,08024421 0,11127814 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,08024421 0,11121404 ! fructose metabolic process GO:0006000 25 16 0,000 0,08024421 0,11115001 ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,08024421 0,11108606 ! intermediate filament-based process GO:0045103 32 16 0,000 0,08024421 0,11102218 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,08024421 0,11095837 ! negative regulation of immune response GO:0050777 35 16 0,000 0,08024421 0,11089464 ! axon cargo transport GO:0008088 43 16 0,000 0,08024421 0,11083098 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,08024421 0,1107674 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,08024421 0,11070388 ! DNA replication initiation GO:0006270 27 16 0,000 0,08024421 0,11064044 ! neuron recognition GO:0008038 35 16 0,000 0,08024421 0,11057707 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,08024421 0,11051378 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,08024421 0,11045056 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,08024421 0,1103874 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,08024421 0,11032433 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,08024421 0,11026132 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,08024421 0,11019839 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,08024421 0,11013552 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,08024421 0,11007273 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,08024421 0,11001001 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,08024421 0,10994736 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,08024421 0,10988479 ! defense response to virus GO:0051607 37 16 0,000 0,08024421 0,10982228 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,08498842 0,11624909 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,08504145 0,11625553 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,08504145 0,11618951 ! metencephalon development GO:0022037 30 17 0,000 0,08504145 0,11612357 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,08504145 0,1160577 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,08504145 0,11599191 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,08504145 0,11592619 ! gene silencing by RNA GO:0031047 36 17 0,000 0,08504145 0,11586055 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,08504145 0,11579498 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,08504145 0,11572948 ! adult walking behavior GO:0007628 33 17 0,000 0,08504145 0,11566406 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,08504145 0,11559872 ! heart looping GO:0001947 30 17 0,000 0,08504145 0,11553344 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,08504145 0,11546824 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,08504145 0,11540312 ! myoblast differentiation GO:0045445 45 17 0,000 0,08504145 0,11533806 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,08504145 0,11527308 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,08504145 0,11520818 ! glycine metabolic process GO:0006544 28 17 0,000 0,08504145 0,11514335 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,08504145 0,11507859 ! NAD metabolic process GO:0019674 29 17 0,000 0,08504145 0,1150139 ! membrane budding GO:0006900 37 17 0,000 0,08504145 0,11494928 ! DNA integration GO:0015074 29 17 0,000 0,08504145 0,11488474 ! regulation of protein binding GO:0043393 33 17 0,000 0,08504145 0,11482027 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,08504145 0,11475588 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,08504145 0,11469155 ! genitalia development GO:0048806 30 17 0,000 0,08504145 0,1146273 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,08504145 0,11456312 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,08504145 0,11449901 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,08504145 0,11443497 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,08504145 0,114371 ! steroid catabolic process GO:0006706 31 17 0,000 0,08504145 0,11430711 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,08504145 0,11424329 ! gas transport GO:0015669 25 17 0,000 0,08504145 0,11417953 ! organic cation transport GO:0015695 31 17 0,000 0,08504145 0,11411585 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,08504145 0,11405224 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,08504145 0,11398871 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,08504145 0,11392524 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,08504145 0,11386184 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,08504145 0,11379851 ! regulation of Rho protein signal transduction GO:0035023 213 95 1,000 0,0881191 0,11785134 ! positive regulation of immune response GO:0050778 156 96 1,000 0,08969727 0,11989534 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,08981382 0,11998449 ! neuron maturation GO:0042551 42 18 0,000 0,08981382 0,1199179 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,08981382 0,11985139 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,08981382 0,11978496 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,08981382 0,11971859 ! memory GO:0007613 31 18 0,000 0,08981382 0,1196523 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,08981382 0,11958609 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,08981382 0,11951994 ! patterning of blood vessels GO:0001569 39 18 0,000 0,08981382 0,11945388 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,08981382 0,11938788 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,08981382 0,11932195 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,08981382 0,1192561 ! response to retinoic acid GO:0032526 26 18 0,000 0,08981382 0,11919033 ! response to fungus GO:0009620 21 18 0,000 0,08981382 0,11912462 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,08981382 0,11905899 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,08981382 0,11899343 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,08981382 0,11892794 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,08981382 0,11886252 ! vitamin transport GO:0051180 27 18 0,000 0,08981382 0,11879717 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,08981382 0,1187319 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,08981382 0,1186667 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,08981382 0,11860157 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,08981382 0,11853651 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,08981382 0,11847152 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,08981382 0,11840661 ! protein ubiquitination GO:0016567 217 97 1,000 0,09128381 0,12027867 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 1,000 0,09448152 0,12442394 ! protein secretion GO:0009306 39 19 0,000 0,09456146 0,1244611 ! positive regulation of translation GO:0045727 30 19 0,000 0,09456146 0,12439305 ! negative regulation of defense response GO:0031348 25 19 0,000 0,09456146 0,12432507 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,09456146 0,12425717 ! skin development GO:0043588 36 19 0,000 0,09456146 0,12418935 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,09456146 0,12412159 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,09456146 0,12405392 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,09456146 0,12398631 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,09456146 0,12391878 ! bile acid metabolic process GO:0008206 29 19 0,000 0,09456146 0,12385132 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,09456146 0,12378394 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,09456146 0,12371663 ! pigmentation during development GO:0048066 41 19 0,000 0,09456146 0,12364939 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,09456146 0,12358223 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,09456146 0,12351514 ! heme metabolic process GO:0042168 36 19 0,000 0,09456146 0,12344812 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,09456146 0,12338117 ! plasma membrane fusion GO:0045026 28 19 0,000 0,09456146 0,1233143 ! peptide cross-linking GO:0018149 37 19 0,000 0,09456146 0,1232475 ! protein export from nucleus GO:0006611 36 19 0,000 0,09456146 0,12318077 ! heart process GO:0003015 30 19 0,000 0,09456146 0,12311411 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,09456146 0,12304753 GO:0006692|prostanoid metabolic process, ! cellular pigmentation GO:0033059 36 19 0,000 0,09456146 0,12298102 ! cell-cell junction organization GO:0045216 35 19 0,000 0,09456146 0,12291458 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,09456146 0,12284821 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,09456146 0,12278191 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,09456146 0,12271569 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,09456146 0,12264953 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,09456146 0,12258345 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,09456146 0,12251744 ! cilium assembly GO:0042384 37 19 0,000 0,09456146 0,1224515 ! peptide hormone secretion GO:0030072 31 19 0,000 0,09456146 0,12238563 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,0992845 0,1284293 ! positive regulation of ossification GO:0045778 47 20 0,000 0,0992845 0,12836029 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,0992845 0,12829135 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,0992845 0,12822249 ! cAMP metabolic process GO:0046058 36 20 0,000 0,0992845 0,1281537 ! response to vitamin GO:0033273 31 20 0,000 0,0992845 0,12808499 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,0992845 0,12801635 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,0992845 0,12794778 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,0992845 0,12787928 ! response to alkaloid GO:0043279 38 20 0,000 0,0992845 0,12781086 ! retinoid metabolic process GO:0001523 32 20 0,000 0,0992845 0,12774251 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,0992845 0,12767424 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,0992845 0,12760604 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,0992845 0,12753791 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,0992845 0,12746985 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,0992845 0,12740187 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,0992845 0,12733396 ! body fluid secretion GO:0007589 31 20 0,000 0,0992845 0,12726612 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,0992845 0,12719835 ! peptide secretion GO:0002790 35 20 0,000 0,0992845 0,12713066 ! stem cell differentiation GO:0048863 53 20 0,000 0,0992845 0,12706303 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,0992845 0,12699548 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,0992845 0,126928 ! sensory perception of pain GO:0019233 30 20 0,000 0,0992845 0,1268606 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,0992845 0,12679326 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,0992845 0,126726 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,0992845 0,1266588 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,0992845 0,12659168 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,0992845 0,12652463 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,0992845 0,12645765 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,0992845 0,12639074 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,0992845 0,1263239 ! regulation of glucose import GO:0046324 29 20 0,000 0,0992845 0,12625714 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,0992845 0,12619044 ! actin filament-based movement GO:0030048 43 20 0,000 0,0992845 0,12612381 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,0992845 0,12605726 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,0992845 0,12599077 ! negative regulation of translation GO:0017148 29 20 0,000 0,0992845 0,12592435 ! regulation of cell killing GO:0031341 42 21 0,000 0,10398305 0,13181413 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,10398305 0,13174472 ! hormone secretion GO:0046879 38 21 0,000 0,10398305 0,13167538 ! glycerol metabolic process GO:0006071 34 21 0,000 0,10398305 0,13160611 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,10398305 0,13153692 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,10398305 0,1314678 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,10398305 0,13139875 ! ovarian follicle development GO:0001541 35 21 0,000 0,10398305 0,13132977 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,10398305 0,13126087 ! smooth muscle contraction GO:0006939 46 21 0,000 0,10398305 0,13119204 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,10398305 0,13112328 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,10398305 0,13105459 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,10398305 0,13098598 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,10398305 0,13091743 ! cytolysis GO:0019835 24 21 0,000 0,10398305 0,13084896 ! vasodilation GO:0042311 39 21 0,000 0,10398305 0,13078056 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,10398305 0,13071224 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,10398305 0,13064398 ! oogenesis GO:0048477 36 21 0,000 0,10398305 0,13057579 ! DNA modification GO:0006304 34 21 0,000 0,10398305 0,13050768 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,10398305 0,13043963 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! detection of biotic stimulus GO:0009595 29 21 0,000 0,10398305 0,13037166 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,10398305 0,13030376 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,10398305 0,13023593 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,10398305 0,13016817 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,10398305 0,13010048 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,10398305 0,13003286 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,10398305 0,12996531 ! collagen catabolic process GO:0030574 28 21 0,000 0,10398305 0,12989783 ! sperm-egg recognition GO:0035036 21 21 0,000 0,10398305 0,12983042 ! gut development GO:0048565 39 21 0,000 0,10398305 0,12976308 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,10865725 0,13552584 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,10865725 0,13545562 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,10865725 0,13538547 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,10865725 0,13531539 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,10865725 0,13524539 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,10865725 0,13517546 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,10865725 0,1351056 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,10865725 0,13503582 ! regeneration GO:0031099 41 22 0,000 0,10865725 0,1349661 ! keratinization GO:0031424 28 22 0,000 0,10865725 0,13489646 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,10865725 0,13482689 ! sensory perception of taste GO:0050909 28 22 0,000 0,10865725 0,13475739 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,10865725 0,13468796 ! vacuolar transport GO:0007034 36 22 0,000 0,10865725 0,13461861 ! lysosome organization GO:0007040 41 22 0,000 0,10865725 0,13454932 ! central nervous system neuron development GO:0021954 46 22 0,000 0,10865725 0,13448011 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,10865725 0,13441097 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,10865725 0,1343419 ! fucose metabolic process GO:0006004 39 22 0,000 0,10865725 0,1342729 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,10865725 0,13420397 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,10865725 0,13413511 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,10865725 0,13406633 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,10865725 0,13399761 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,10865725 0,13392896 ! sarcomere organization GO:0045214 30 22 0,000 0,10865725 0,13386039 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,10865725 0,13379188 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,10865725 0,13372345 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,10865725 0,13365508 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,11330722 0,13930361 ! viral genome replication GO:0019079 41 23 0,000 0,11330722 0,13923246 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,11330722 0,13916139 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,11330722 0,13909039 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,11330722 0,13901946 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,11330722 0,13894861 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,11330722 0,13887782 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,11330722 0,13880711 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,11330722 0,13873647 ! response to ethanol GO:0045471 46 23 0,000 0,11330722 0,1386659 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,11330722 0,13859541 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,11330722 0,13852498 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,11330722 0,13845463 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,11330722 0,13838435 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,11330722 0,13831414 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,11330722 0,138244 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 38 23 0,000 0,11330722 0,13817393 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,11330722 0,13810393 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,11330722 0,13803401 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,11330722 0,13796415 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,11330722 0,13789437 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,11330722 0,13782465 ! fatty acid transport GO:0015908 44 23 0,000 0,11330722 0,13775501 ! platelet activation GO:0030168 37 23 0,000 0,11330722 0,13768544 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,11330722 0,13761593 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,11330722 0,1375465 ! hormone transport GO:0009914 40 23 0,000 0,11330722 0,13747714 ! cell-cell recognition GO:0009988 25 23 0,000 0,11330722 0,13740784 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,11330722 0,13733862 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,11330722 0,13726947 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,11330722 0,13720038 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,11330722 0,13713137 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,11793308 0,14265812 GO:0016444|somatic cell DNA recombination, ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,11793308 0,14258643 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,11793308 0,14251481 ! vesicle docking GO:0048278 47 24 0,000 0,11793308 0,14244327 ! vacuole organization GO:0007033 43 24 0,000 0,11793308 0,1423718 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,11793308 0,1423004 ! digestive system process GO:0022600 39 24 0,000 0,11793308 0,14222907 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,11793308 0,14215781 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,11793308 0,14208663 ! regulation of behavior GO:0050795 43 24 0,000 0,11793308 0,14201551 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,11793308 0,14194447 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,11793308 0,1418735 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,11793308 0,1418026 ! membrane depolarization GO:0051899 39 24 0,000 0,11793308 0,14173176 ! pentose metabolic process GO:0019321 35 24 0,000 0,11793308 0,14166101 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,11793308 0,14159032 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,11793308 0,1415197 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,11793308 0,14144915 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,11793308 0,14137867 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,11793308 0,14130826 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,11793308 0,14123793 ! regulation of amine transport GO:0051952 40 24 0,000 0,11793308 0,14116766 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,12253497 0,14660325 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,12253497 0,14653038 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,12253497 0,14645759 ! phototransduction GO:0007602 33 25 0,000 0,12253497 0,14638487 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,12253497 0,14631222 GO:0006479|protein amino acid methylation, ! sperm motility GO:0030317 31 25 0,000 0,12253497 0,14623965 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,12253497 0,14616714 ! chromosome condensation GO:0030261 45 25 0,000 0,12253497 0,14609471 ! neural crest cell development GO:0014032 54 25 0,000 0,12253497 0,14602235 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,12253497 0,14595006 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,12253497 0,14587785 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,12253497 0,1458057 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,12253497 0,14573363 ! immunoglobulin production GO:0002377 55 25 0,000 0,12253497 0,14566162 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,12253497 0,14558969 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,12253497 0,14551783 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,12253497 0,14544604 ! telomere organization GO:0032200 43 25 0,000 0,12253497 0,14537432 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,12253497 0,14530267 GO:0060606|tube closure, ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,12711299 0,15065707 ! embryonic pattern specification GO:0009880 44 26 0,000 0,12711299 0,1505829 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,12711299 0,15050879 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,12711299 0,15043476 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,12711299 0,1503608 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,12711299 0,15028691 ! tube lumen formation GO:0035148 50 26 0,000 0,12711299 0,1502131 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,12711299 0,15013935 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,12711299 0,15006568 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,12711299 0,14999209 GO:0051297|centrosome organization, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,12711299 0,14991856 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,12711299 0,14984511 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,12711299 0,14977172 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,12711299 0,14969842 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,12711299 0,14962518 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,12711299 0,14955201 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,12711299 0,14947892 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,12711299 0,14940589 ! blastocyst development GO:0001824 49 26 0,000 0,12711299 0,14933294 ! leukocyte proliferation GO:0070661 52 26 0,000 0,12711299 0,14926006 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,12711299 0,14918725 ! neuron fate commitment GO:0048663 48 27 0,000 0,13166729 0,15445709 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,13166729 0,15438182 ! iron ion transport GO:0006826 59 27 0,000 0,13166729 0,15430662 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,13166729 0,1542315 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,13166729 0,15415644 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,13166729 0,15408147 ! fat cell differentiation GO:0045444 50 27 0,000 0,13166729 0,15400656 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,13166729 0,15393173 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,13166729 0,15385697 ! autophagy GO:0006914 41 27 0,000 0,13166729 0,15378228 ! male gonad development GO:0008584 44 27 0,000 0,13166729 0,15370766 ! response to toxin GO:0009636 47 27 0,000 0,13166729 0,15363312 ! primary neural tube formation GO:0014020 51 27 0,000 0,13166729 0,15355865 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,13166729 0,15348425 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,13166729 0,15340992 ! glutathione metabolic process GO:0006749 39 27 0,000 0,13166729 0,15333567 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,13166729 0,15326149 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,13166729 0,15318738 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,13619797 0,15838198 ! circadian rhythm GO:0007623 50 28 0,000 0,13619797 0,15830547 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,13619797 0,15822903 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,13619797 0,15815266 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,13619797 0,15807637 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,13619797 0,15800015 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,13619797 0,15792401 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,13619797 0,15784794 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,13619797 0,15777194 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,13619797 0,15769601 ! synaptogenesis GO:0007416 42 28 0,000 0,13619797 0,15762016 ! lipid oxidation GO:0034440 43 28 0,000 0,13619797 0,15754438 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,13619797 0,15746868 ! translational initiation GO:0006413 65 29 0,000 0,14070516 0,16260164 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,14070516 0,16252358 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,14070516 0,1624456 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,14070516 0,16236768 ! catechol metabolic process GO:0009712 54 29 0,000 0,14070516 0,16228985 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,14070516 0,16221208 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,14070516 0,1621344 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,14070516 0,16205678 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,14070516 0,16197924 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 55 29 0,000 0,14070516 0,16190178 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,14070516 0,16182439 ! detection of light stimulus GO:0009583 38 29 0,000 0,14070516 0,16174707 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,14070516 0,16166983 ! tissue homeostasis GO:0001894 48 29 0,000 0,14070516 0,16159266 GO:0048871|multicellular organismal homeostasis, ! phenol metabolic process GO:0018958 55 30 0,000 0,14518899 0,16666255 ! zinc ion transport GO:0006829 45 30 0,000 0,14518899 0,16658307 ! membrane docking GO:0022406 61 30 0,000 0,14518899 0,16650367 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,14518899 0,16642435 ! regulation of innate immune response GO:0045088 51 30 0,000 0,14518899 0,1663451 ! acute-phase response GO:0006953 49 30 0,000 0,14518899 0,16626592 ! myofibril assembly GO:0030239 47 30 0,000 0,14518899 0,16618682 GO:0055002|striated muscle cell development, ! determination of left/right symmetry GO:0007368 47 30 0,000 0,14518899 0,1661078 ! phospholipid transport GO:0015914 51 30 0,000 0,14518899 0,16602885 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,14518899 0,16594998 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,14518899 0,16587118 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,14518899 0,16579245 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,14964956 0,17080495 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,14964956 0,17072397 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,14964956 0,17064305 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,14964956 0,17056222 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,14964956 0,17048146 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,14964956 0,17040078 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,14964956 0,17032017 ! ovulation cycle process GO:0022602 49 31 0,000 0,14964956 0,17023964 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,14964956 0,17015919 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,14964956 0,17007881 ! peptide transport GO:0015833 55 31 0,000 0,14964956 0,16999851 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,14964956 0,16991828 ! iron ion homeostasis GO:0055072 54 31 0,000 0,14964956 0,16983813 ! natural killer cell activation GO:0030101 45 31 0,000 0,14964956 0,16975806 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,14964956 0,16967806 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,14964956 0,16959814 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,14964956 0,16951829 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,15408701 0,17446275 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,15408701 0,17438069 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,15408701 0,1742987 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,15408701 0,1742168 ! cholesterol transport GO:0030301 56 32 0,000 0,15408701 0,17413497 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,15408701 0,17405321 ! spliceosome assembly GO:0000245 67 32 0,000 0,15408701 0,17397154 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,15408701 0,17388993 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,15408701 0,17380841 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,15408701 0,17372696 ! muscle cell development GO:0055001 49 32 0,000 0,15408701 0,17364559 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,15408701 0,1735643 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,15408701 0,17348308 ! ovulation cycle GO:0042698 51 32 0,000 0,15408701 0,17340194 ! BMP signaling pathway GO:0030509 64 32 0,000 0,15408701 0,17332087 ! hindbrain development GO:0030902 61 32 0,000 0,15408701 0,17323988 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,15408701 0,17315896 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,15408701 0,17307812 ! gene silencing GO:0016458 65 32 0,000 0,15408701 0,17299736 ! post-embryonic development GO:0009791 69 33 0,000 0,15850145 0,17787056 ! protein targeting to membrane GO:0006612 68 33 0,000 0,15850145 0,17778763 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,15850145 0,17770479 ! ceramide metabolic process GO:0006672 64 33 0,000 0,15850145 0,17762202 ! sterol transport GO:0015918 57 33 0,000 0,15850145 0,17753933 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,15850145 0,17745671 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,15850145 0,17737418 ! adult locomotory behavior GO:0008344 59 33 0,000 0,15850145 0,17729171 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,15850145 0,17720933 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,16289299 0,18203462 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,16289299 0,18195011 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,16289299 0,18186568 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,16289299 0,18178133 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,16289299 0,18169705 ! mismatch repair GO:0006298 46 34 0,000 0,16289299 0,18161285 ! spermatid development GO:0007286 63 34 0,000 0,16289299 0,18152873 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,16289299 0,18144469 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,16289299 0,18136073 ! regulation of muscle development GO:0048634 70 35 0,000 0,16726176 0,18613867 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,16726176 0,18605261 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,16726176 0,18596664 ! odontogenesis GO:0042476 66 35 0,000 0,16726176 0,18588074 ! female gonad development GO:0008585 58 35 0,000 0,16726176 0,18579492 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,16726176 0,18570919 GO:0006639|acylglycerol metabolic process, ! cytokine production GO:0001816 59 35 0,000 0,16726176 0,18562353 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,16726176 0,18553795 ! neural tube formation GO:0001841 67 35 0,000 0,16726176 0,18545244 ! vesicle localization GO:0051648 64 35 0,000 0,16726176 0,18536702 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,17160788 0,19009602 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,17160788 0,19000854 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,17160788 0,18992114 ! positive regulation of cell development GO:0010720 80 36 0,000 0,17160788 0,18983382 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,17160788 0,18974658 ! aerobic respiration GO:0009060 55 36 0,000 0,17160788 0,18965942 ! embryonic organ development GO:0048568 57 36 0,000 0,17160788 0,18957234 ! RNA export from nucleus GO:0006405 56 37 0,000 0,17593146 0,19425934 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,17593146 0,19417023 ! actomyosin structure organization GO:0031032 62 37 0,000 0,17593146 0,1940812 ! organic anion transport GO:0015711 68 37 0,000 0,17593146 0,19399225 ! tissue remodeling GO:0048771 76 37 0,000 0,17593146 0,19390339 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,17593146 0,1938146 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,17593146 0,1937259 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,17593146 0,19363728 GO:0015986|ATP synthesis coupled proton transport, ! spermatid differentiation GO:0048515 66 37 0,000 0,17593146 0,19354874 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,18023262 0,19818998 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,18023262 0,19809944 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,18023262 0,19800898 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,18023262 0,19791861 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,18023262 0,19782832 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 67 38 0,000 0,18023262 0,19773811 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,18023262 0,19764798 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,18023262 0,19755794 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,18023262 0,19746798 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,18023262 0,19737809 ! mRNA catabolic process GO:0006402 71 39 0,000 0,18451146 0,20197206 ! organic ether metabolic process GO:0018904 55 39 0,000 0,18451146 0,20188021 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,18451146 0,20178845 ! ion transmembrane transport GO:0034220 66 39 0,000 0,18451146 0,20169677 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,18451146 0,20160517 ! RNA modification GO:0009451 57 39 0,000 0,18451146 0,20151366 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,18451146 0,20142222 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,18876812 0,20597555 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,18876812 0,20588218 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,18876812 0,2057889 ! feeding behavior GO:0007631 59 40 0,000 0,18876812 0,2056957 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,18876812 0,20560258 ! mesenchymal cell development GO:0014031 87 40 0,000 0,18876812 0,20550955 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,18876812 0,2054166 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,1930027 0,2099297 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,1930027 0,20983484 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,1930027 0,20974006 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,1930027 0,20964537 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,1930027 0,20955076 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,1930027 0,20945624 ! female gamete generation GO:0007292 61 41 0,000 0,1930027 0,20936181 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,19721531 0,21383508 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,19721531 0,21373876 ! regulation of tube size GO:0035150 71 42 0,000 0,19721531 0,21364252 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,19721531 0,21354637 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,19721531 0,21345031 ! neuron migration GO:0001764 79 42 0,000 0,19721531 0,21335433 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,20140608 0,21779012 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,20140608 0,21769228 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,20140608 0,21759453 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,20140608 0,21749687 ! neural tube development GO:0021915 77 43 0,000 0,20140608 0,21739929 ! striated muscle contraction GO:0006941 77 43 0,000 0,20140608 0,2173018 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,20140608 0,2172044 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,2055751 0,22160112 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,2055751 0,22150188 ! male sex differentiation GO:0046661 76 44 0,000 0,2055751 0,22140273 ! biopolymer methylation GO:0043414 84 44 0,000 0,2055751 0,22130366 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,2055751 0,22120469 ! glycolysis GO:0006096 65 45 0,000 0,2097225 0,22556653 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,2097225 0,22546574 ! leukocyte migration GO:0050900 68 45 0,000 0,2097225 0,22536504 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,2097225 0,22526443 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,2097225 0,22516391 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,2097225 0,22506348 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,2097225 0,22496314 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,2097225 0,22486289 ! cell growth GO:0016049 84 45 0,000 0,2097225 0,22476273 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,21384838 0,22908246 ! positive regulation of defense response GO:0031349 76 47 0,000 0,21795286 0,23337543 ! response to calcium ion GO:0051592 81 47 0,000 0,21795286 0,23327161 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,21795286 0,23316789 ! methylation GO:0032259 90 47 0,000 0,21795286 0,23306426 ! protein homooligomerization GO:0051260 76 47 0,000 0,21795286 0,23296072 ! Notch signaling pathway GO:0007219 96 48 0,000 0,22203605 0,23721968 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,22203605 0,23711439 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,22203605 0,2370092 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,22203605 0,23690409 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,22609805 0,24113116 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,22609805 0,24102433 ! regulation of ion transport GO:0043269 77 49 0,000 0,22609805 0,24091758 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,22609805 0,24081094 ! peptide metabolic process GO:0006518 76 49 0,000 0,22609805 0,24070438 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,22609805 0,24059792 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,22609805 0,24049156 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,22609805 0,24038529 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,22609805 0,24027911 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,22609805 0,24017303 ! neuromuscular process GO:0050905 99 50 0,000 0,23013898 0,24435762 ! regulation of ossification GO:0030278 117 50 0,000 0,23013898 0,24424984 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,23013898 0,24414214 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,23415894 0,24829723 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,23415894 0,24818784 ! excretion GO:0007588 83 51 0,000 0,23415894 0,24807856 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,23415894 0,24796937 ! chromatin remodeling GO:0006338 109 51 0,000 0,23415894 0,24786027 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,23415894 0,24775128 ! vesicle organization GO:0016050 107 51 0,000 0,23415894 0,24764238 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,23815804 0,25176109 ! membrane fusion GO:0006944 110 52 0,000 0,23815804 0,25165053 ! amino acid activation GO:0043038 92 52 0,000 0,23815804 0,25154006 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 76 53 0,000 0,24213639 0,25562973 ! RNA catabolic process GO:0006401 93 53 0,000 0,24213639 0,25551762 ! regulation of translational initiation GO:0006446 82 53 0,000 0,24213639 0,2554056 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,24213639 0,25529367 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,2460941 0,25935279 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,2460941 0,25923924 ! cell recognition GO:0008037 85 54 0,000 0,2460941 0,25912578 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,2460941 0,25901243 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,2460941 0,25889918 ! chloride transport GO:0006821 90 55 0,000 0,25003128 0,26292625 ! glucose catabolic process GO:0006007 82 55 0,000 0,25003128 0,26281138 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,25003128 0,26269662 ! RNA elongation GO:0006354 79 55 0,000 0,25003128 0,26258195 ! nuclear export GO:0051168 97 55 0,000 0,25003128 0,26246739 ! sensory perception of smell GO:0007608 80 56 0,000 0,25394802 0,26646268 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,25394802 0,26634653 ! proton transport GO:0015992 94 56 0,000 0,25394802 0,26623047 ! hydrogen transport GO:0006818 97 58 0,000 0,26172063 0,27425951 ! adult behavior GO:0030534 99 58 0,000 0,26172063 0,27414011 ! positive regulation of secretion GO:0051047 95 59 0,000 0,26557671 0,27805812 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,26557671 0,27793717 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,26557671 0,27781633 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,26941277 0,28170671 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,26941277 0,28158433 ! regulation of heart contraction GO:0008016 110 60 0,000 0,26941277 0,28146206 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,26941277 0,2813399 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,27322893 0,28520122 ! tRNA processing GO:0008033 89 61 0,000 0,27322893 0,28507754 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,27322893 0,28495397 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,27702528 0,28878805 ! gonad development GO:0008406 98 62 0,000 0,27702528 0,28866298 ! detection of external stimulus GO:0009581 91 63 0,000 0,28080192 0,29247161 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,28080192 0,29234506 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,28455896 0,2961284 ! cell redox homeostasis GO:0045454 102 64 0,000 0,28455896 0,29600037 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,28455896 0,29587246 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,28455896 0,29574465 GO:0048609|reproductive process in a multicellular organism, ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,2882965 0,29949973 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,2882965 0,29937047 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,2882965 0,29924132 GO:0035113|embryonic appendage morphogenesis, ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,29201464 0,30296991 ! secondary metabolic process GO:0019748 116 66 0,000 0,29201464 0,30283932 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,29571347 0,30654314 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,29571347 0,30641112 ! hexose catabolic process GO:0019320 104 67 0,000 0,29571347 0,30627922 ! adaptive immune response GO:0002250 119 67 0,000 0,29571347 0,30614743 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,29571347 0,30601575 ! amino acid transport GO:0006865 125 68 0,000 0,29939311 0,30969038 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,29939311 0,30955729 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,29939311 0,30942432 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,29939311 0,30929146 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,30305364 0,31293865 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,30305364 0,3128044 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,30305364 0,31267026 ! antigen processing and presentation GO:0019882 104 69 0,000 0,30305364 0,31253624 ! appendage morphogenesis GO:0035107 135 70 0,000 0,30669516 0,3161562 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,31031778 0,31975357 ! reproductive structure development GO:0048608 113 71 0,000 0,31031778 0,31961669 ! appendage development GO:0048736 136 71 0,000 0,31031778 0,31947993 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,31031778 0,31934328 ! acute inflammatory response GO:0002526 113 72 0,000 0,31392159 0,32291379 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,31392159 0,32277579 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,31392159 0,32263791 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,31392159 0,32250015 ! regulation of blood pressure GO:0008217 125 73 0,000 0,31750669 0,32604401 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,31750669 0,32590491 ! transition metal ion transport GO:0000041 126 74 0,000 0,32107318 0,32942519 ! neurotransmitter transport GO:0006836 123 74 0,000 0,32107318 0,32928477 ! exocytosis GO:0006887 133 74 0,000 0,32107318 0,32914447 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,32107318 0,32900429 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,32462114 0,33249828 ! rhythmic process GO:0048511 128 75 0,000 0,32462114 0,3323568 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,32815068 0,33582754 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,32815068 0,33568476 ! defense response to bacterium GO:0042742 89 76 0,000 0,32815068 0,33554209 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,32815068 0,33539955 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,32815068 0,33525713 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,3316619 0,33870056 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,3316619 0,33855686 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,33515488 0,34197737 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,33515488 0,3418324 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,33862971 0,34523012 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,33862971 0,3450839 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,33862971 0,3449378 ! response to metal ion GO:0010038 140 80 0,000 0,34208651 0,34831153 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,34208651 0,34816419 ! inorganic anion transport GO:0015698 138 80 0,000 0,34208651 0,34801697 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,34552535 0,35136686 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,34894633 0,35469576 ! response to nutrient GO:0007584 125 82 0,000 0,34894633 0,35454597 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,35573507 0,36129108 ! response to unfolded protein GO:0006986 131 85 0,000 0,35910302 0,36455775 ! nucleosome assembly GO:0006334 122 85 0,000 0,35910302 0,36440399 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,35910302 0,36425036 ! amine biosynthetic process GO:0009309 138 86 0,000 0,36245347 0,36749391 ! response to inorganic substance GO:0010035 153 86 0,000 0,36245347 0,36733911 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,36245347 0,36718444 ! chromatin assembly GO:0031497 124 86 0,000 0,36245347 0,3670299 ! alcohol catabolic process GO:0046164 130 86 0,000 0,36245347 0,3668755 ! amine transport GO:0015837 155 86 0,000 0,36245347 0,36672122 ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,36578652 0,36993794 ! cellular respiration GO:0045333 135 88 0,000 0,36910226 0,37313447 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,36910226 0,37297775 ! regulation of neurological system process GO:0031644 148 88 0,000 0,36910226 0,37282117 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,36910226 0,37266472 ! cellular defense response GO:0006968 114 89 0,000 0,37240077 0,37583735 ! sex differentiation GO:0007548 145 90 0,000 0,37568214 0,37899003 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,37568214 0,37883119 ! sterol metabolic process GO:0016125 152 91 0,000 0,37894646 0,3819628 ! response to protein stimulus GO:0051789 149 91 0,000 0,37894646 0,38180285 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,37894646 0,38164303 ! regulation of defense response GO:0031347 149 92 0,000 0,38219383 0,38475245 ! nucleosome organization GO:0034728 138 92 0,000 0,38219383 0,38459153 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,38219383 0,38443075 ! vitamin metabolic process GO:0006766 139 92 0,000 0,38219383 0,3842701 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,38542432 0,38735628 GO:0010498|proteasomal protein catabolic process, ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,38863803 0,39042301 ! female pregnancy GO:0007565 164 94 0,000 0,38863803 0,39026006 ! transcription initiation GO:0006352 153 94 0,000 0,38863803 0,39009725 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,39501544 0,39633326 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,39501544 0,39616805 ! detection of stimulus GO:0051606 151 96 0,000 0,39501544 0,39600298 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,39817931 0,39900851 ! hormone metabolic process GO:0042445 157 97 0,000 0,39817931 0,39884239 ! response to virus GO:0009615 160 98 0,000 0,40132674 0,40182777 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,40132674 0,40166062 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,40132674 0,40149361 GO:0016054|organic acid catabolic process, ! Golgi vesicle transport GO:0048193 207 99 0,000 0,40445781 0,40445781