Study run-a2
Study informations
103 subnetworks in total page | file
306 genes associated page | file
Enriched GO terms page
General informations
General Index page
Study Index page
Subnetwork 6698-8-real
score
| Dataset | Score | P-val 1 | P-val 2 | P-val 3 |
|---|
| Desmedt | 0.1416 | 1.150e-02 | 8.776e-03 | 9.740e-02 |
|---|
| IPC-NIBC-129 | 0.2240 | 3.727e-02 | 5.431e-02 | 3.671e-01 |
|---|
| Ivshina_GPL96-GPL97 | 0.2431 | 3.682e-03 | 6.673e-03 | 1.520e-01 |
|---|
| Loi_GPL570 | 0.2842 | 3.598e-02 | 4.129e-02 | 1.673e-01 |
|---|
| Loi_GPL96-GPL97 | 0.1533 | 1.800e-05 | 1.450e-04 | 1.600e-04 |
|---|
| Parker_GPL1390 | 0.2856 | 2.020e-02 | 2.614e-02 | 2.315e-01 |
|---|
| Parker_GPL887 | 0.2020 | 5.101e-01 | 5.288e-01 | 5.749e-01 |
|---|
| Pawitan_GPL96-GPL97 | 0.2770 | 2.014e-01 | 1.433e-01 | 7.546e-01 |
|---|
| Schmidt | 0.3056 | 2.792e-02 | 3.300e-02 | 2.916e-01 |
|---|
| Sotiriou | 0.3681 | 4.750e-03 | 3.558e-03 | 1.216e-01 |
|---|
| Van-De-Vijver | 0.2783 | 6.120e-04 | 8.800e-04 | 4.205e-02 |
|---|
| Zhang | 0.2504 | 1.484e-01 | 9.985e-02 | 3.048e-01 |
|---|
| Zhou | 0.4478 | 1.402e-01 | 1.420e-01 | 6.350e-01 |
|---|
Expression data for subnetwork 6698-8-real in each dataset
Desmedt |
IPC-NIBC-129 |
Ivshina_GPL96-GPL97 |
Loi_GPL570 |
Loi_GPL96-GPL97 |
Parker_GPL1390 |
Parker_GPL887 |
Pawitan_GPL96-GPL97 |
Schmidt |
Sotiriou |
Van-De-Vijver |
Zhang |
Zhou |
Subnetwork structure for each dataset
- Desmedt
Score for each gene in subnetwork 6698-8-real in each dataset
| Gene Symbol | Links | Frequency | Frequency Rank | Subnetwork score rank | Global rank |
Desmedt | IPC-NIBC-129 | Ivshina_GPL96-GPL97 | Loi_GPL570 | Loi_GPL96-GPL97 | Parker_GPL1390 | Parker_GPL887 | Pawitan_GPL96-GPL97 | Schmidt | Sotiriou | Van-De-Vijver | Zhang | Zhou |
|---|
| irak1 |   | 5 | 40 | 42 | 36 | -0.016 | 0.242 | 0.007 | 0.133 | 0.108 | 0.303 | 0.257 | 0.133 | 0.177 | 0.084 | 0.199 | -0.026 | 0.081 |
|---|
| cttn | | 10 | 20 | 1 | 6 | 0.067 | 0.065 | 0.123 | 0.238 | 0.126 | 0.263 | -0.172 | 0.216 | 0.069 | 0.115 | undef | 0.025 | 0.279 |
|---|
| cdkn1a | | 44 | 7 | 1 | 4 | 0.115 | -0.020 | 0.065 | 0.082 | 0.099 | 0.124 | 0.055 | 0.087 | 0.068 | 0.144 | undef | -0.201 | 0.069 |
|---|
| reps2 | | 3 | 62 | 56 | 56 | -0.033 | -0.139 | 0.057 | 0.122 | 0.113 | -0.154 | 0.105 | -0.157 | 0.079 | 0.124 | 0.052 | 0.303 | 0.220 |
|---|
| prkci | | 14 | 15 | 31 | 26 | 0.065 | 0.104 | 0.012 | 0.170 | 0.112 | 0.088 | -0.103 | -0.170 | 0.196 | 0.128 | 0.049 | 0.124 | 0.149 |
|---|
| casp3 | | 2 | 78 | 103 | 102 | -0.051 | 0.158 | 0.146 | 0.160 | 0.074 | 0.210 | 0.252 | 0.202 | 0.070 | 0.073 | -0.058 | 0.059 | 0.305 |
|---|
| tsc1 | | 58 | 4 | 18 | 13 | 0.049 | 0.012 | -0.055 | 0.072 | 0.055 | -0.144 | -0.242 | -0.196 | 0.006 | 0.010 | 0.095 | -0.007 | 0.207 |
|---|
| cdc2 | | 96 | 1 | 1 | 1 | 0.073 | 0.247 | 0.206 | 0.172 | 0.247 | 0.153 | -0.131 | 0.282 | 0.226 | 0.221 | 0.162 | 0.297 | 0.336 |
|---|
| hras | | 14 | 15 | 42 | 34 | 0.049 | -0.030 | 0.094 | 0.210 | 0.160 | 0.195 | 0.022 | 0.245 | 0.086 | 0.208 | 0.180 | 0.003 | 0.197 |
|---|
| sprr1a | | 1 | 116 | 103 | 114 | 0.102 | 0.150 | 0.079 | 0.111 | 0.079 | 0.026 | 0.245 | 0.195 | 0.067 | -0.056 | -0.037 | -0.036 | -0.116 |
|---|
| sfn | | 61 | 3 | 1 | 2 | 0.077 | 0.137 | 0.111 | 0.172 | 0.112 | 0.119 | 0.141 | 0.219 | 0.100 | 0.147 | 0.158 | 0.079 | 0.181 |
|---|
| acta1 | | 9 | 22 | 1 | 7 | -0.003 | 0.098 | -0.008 | -0.030 | 0.119 | 0.174 | 0.376 | 0.024 | 0.182 | 0.214 | 0.100 | 0.048 | 0.201 |
|---|
| birc5 | | 5 | 40 | 103 | 89 | 0.101 | 0.216 | 0.190 | 0.134 | 0.223 | 0.149 | 0.166 | 0.202 | 0.236 | 0.241 | undef | 0.205 | 0.400 |
|---|
| map2k1 | | 10 | 20 | 54 | 44 | 0.154 | 0.096 | 0.093 | 0.013 | 0.095 | 0.045 | -0.223 | 0.207 | 0.082 | 0.096 | undef | undef | 0.230 |
|---|
| grb2 | | 9 | 22 | 1 | 7 | 0.084 | -0.013 | 0.086 | -0.031 | 0.162 | -0.038 | 0.003 | 0.065 | 0.158 | 0.127 | 0.149 | 0.194 | -0.005 |
|---|
GO Enrichment output for subnetwork 6698-8-real in each dataset
| Name | Accession Number | Link | P-val | Corrected P-val |
|---|
| keratinocyte differentiation | GO:0030216 |  | 7.063E-12 | 1.624E-08 |
|---|
| epidermal cell differentiation | GO:0009913 | | 1.662E-11 | 1.912E-08 |
|---|
| negative regulation of cyclin-dependent protein kinase activity | GO:0045736 | | 1.44E-07 | 1.104E-04 |
|---|
| induction of apoptosis by intracellular signals | GO:0008629 | | 2.87E-07 | 1.651E-04 |
|---|
| regulation of B cell proliferation | GO:0030888 | | 3.08E-07 | 1.417E-04 |
|---|
| regulation of cyclin-dependent protein kinase activity | GO:0000079 | | 7.766E-07 | 2.977E-04 |
|---|
| negative regulation of caspase activity | GO:0043154 | | 9.306E-07 | 3.058E-04 |
|---|
| release of cytochrome c from mitochondria | GO:0001836 | | 9.306E-07 | 2.676E-04 |
|---|
| negative regulation of protein kinase activity | GO:0006469 | | 1.221E-06 | 3.119E-04 |
|---|
| negative regulation of kinase activity | GO:0033673 | | 1.31E-06 | 3.012E-04 |
|---|
| negative regulation of transferase activity | GO:0051348 | | 1.606E-06 | 3.359E-04 |
|---|
IPC-NIBC-129 file
| Name | Accession Number | Link | P-val | Corrected P-val |
|---|
| keratinocyte differentiation | GO:0030216 | | 1.689E-12 | 4.126E-09 |
|---|
| epidermal cell differentiation | GO:0009913 | | 3.286E-12 | 4.013E-09 |
|---|
| induction of apoptosis by intracellular signals | GO:0008629 | | 5.995E-08 | 4.882E-05 |
|---|
| negative regulation of cyclin-dependent protein kinase activity | GO:0045736 | | 6.484E-08 | 3.96E-05 |
|---|
| regulation of B cell proliferation | GO:0030888 | | 1.187E-07 | 5.802E-05 |
|---|
| regulation of cyclin-dependent protein kinase activity | GO:0000079 | | 1.578E-07 | 6.426E-05 |
|---|
| negative regulation of caspase activity | GO:0043154 | | 1.962E-07 | 6.849E-05 |
|---|
| release of cytochrome c from mitochondria | GO:0001836 | | 1.962E-07 | 5.993E-05 |
|---|
| negative regulation of protein kinase activity | GO:0006469 | | 3.43E-07 | 9.31E-05 |
|---|
| negative regulation of kinase activity | GO:0033673 | | 3.636E-07 | 8.882E-05 |
|---|
| negative regulation of peptidase activity | GO:0010466 | | 3.66E-07 | 8.128E-05 |
|---|
Ivshina_GPL96-GPL97 file
| Name | Accession Number | Link | P-val | Corrected P-val |
|---|
| keratinocyte differentiation | GO:0030216 | | 2.015E-12 | 4.848E-09 |
|---|
| epidermal cell differentiation | GO:0009913 | | 4.184E-12 | 5.033E-09 |
|---|
| negative regulation of cyclin-dependent protein kinase activity | GO:0045736 | | 9.588E-08 | 7.69E-05 |
|---|
| induction of apoptosis by intracellular signals | GO:0008629 | | 1.005E-07 | 6.044E-05 |
|---|
| regulation of B cell proliferation | GO:0030888 | | 1.756E-07 | 8.448E-05 |
|---|
| regulation of cyclin-dependent protein kinase activity | GO:0000079 | | 2.643E-07 | 1.06E-04 |
|---|
| negative regulation of caspase activity | GO:0043154 | | 2.901E-07 | 9.971E-05 |
|---|
| release of cytochrome c from mitochondria | GO:0001836 | | 2.901E-07 | 8.725E-05 |
|---|
| negative regulation of protein kinase activity | GO:0006469 | | 5.094E-07 | 1.362E-04 |
|---|
| negative regulation of kinase activity | GO:0033673 | | 5.409E-07 | 1.301E-04 |
|---|
| negative regulation of peptidase activity | GO:0010466 | | 5.409E-07 | 1.183E-04 |
|---|
Loi_GPL570 file
| Name | Accession Number | Link | P-val | Corrected P-val |
|---|
| keratinocyte differentiation | GO:0030216 | | 1.689E-12 | 4.126E-09 |
|---|
| epidermal cell differentiation | GO:0009913 | | 3.286E-12 | 4.013E-09 |
|---|
| induction of apoptosis by intracellular signals | GO:0008629 | | 5.995E-08 | 4.882E-05 |
|---|
| negative regulation of cyclin-dependent protein kinase activity | GO:0045736 | | 6.484E-08 | 3.96E-05 |
|---|
| regulation of B cell proliferation | GO:0030888 | | 1.187E-07 | 5.802E-05 |
|---|
| regulation of cyclin-dependent protein kinase activity | GO:0000079 | | 1.578E-07 | 6.426E-05 |
|---|
| negative regulation of caspase activity | GO:0043154 | | 1.962E-07 | 6.849E-05 |
|---|
| release of cytochrome c from mitochondria | GO:0001836 | | 1.962E-07 | 5.993E-05 |
|---|
| negative regulation of protein kinase activity | GO:0006469 | | 3.43E-07 | 9.31E-05 |
|---|
| negative regulation of kinase activity | GO:0033673 | | 3.636E-07 | 8.882E-05 |
|---|
| negative regulation of peptidase activity | GO:0010466 | | 3.66E-07 | 8.128E-05 |
|---|
Loi_GPL96-GPL97 file
| Name | Accession Number | Link | P-val | Corrected P-val |
|---|
| keratinocyte differentiation | GO:0030216 | | 2.015E-12 | 4.848E-09 |
|---|
| epidermal cell differentiation | GO:0009913 | | 4.184E-12 | 5.033E-09 |
|---|
| negative regulation of cyclin-dependent protein kinase activity | GO:0045736 | | 9.588E-08 | 7.69E-05 |
|---|
| induction of apoptosis by intracellular signals | GO:0008629 | | 1.005E-07 | 6.044E-05 |
|---|
| regulation of B cell proliferation | GO:0030888 | | 1.756E-07 | 8.448E-05 |
|---|
| regulation of cyclin-dependent protein kinase activity | GO:0000079 | | 2.643E-07 | 1.06E-04 |
|---|
| negative regulation of caspase activity | GO:0043154 | | 2.901E-07 | 9.971E-05 |
|---|
| release of cytochrome c from mitochondria | GO:0001836 | | 2.901E-07 | 8.725E-05 |
|---|
| negative regulation of protein kinase activity | GO:0006469 | | 5.094E-07 | 1.362E-04 |
|---|
| negative regulation of kinase activity | GO:0033673 | | 5.409E-07 | 1.301E-04 |
|---|
| negative regulation of peptidase activity | GO:0010466 | | 5.409E-07 | 1.183E-04 |
|---|
Parker_GPL1390 file
| Name | Accession Number | Link | P-val | Corrected P-val |
|---|
| keratinocyte differentiation | GO:0030216 | | 3.269E-10 | 1.167E-06 |
|---|
| protein serine/threonine kinase inhibitor activity | GO:0030291 | | 5.077E-10 | 9.065E-07 |
|---|
| epidermal cell differentiation | GO:0009913 | | 5.8E-10 | 6.903E-07 |
|---|
| protein kinase inhibitor activity | GO:0004860 | | 1.031E-08 | 9.201E-06 |
|---|
| kinase inhibitor activity | GO:0019210 | | 1.378E-08 | 9.841E-06 |
|---|
| cyclin-dependent protein kinase inhibitor activity | GO:0004861 | | 3.814E-08 | 2.27E-05 |
|---|
| negative regulation of cyclin-dependent protein kinase activity | GO:0045736 | | 5.717E-08 | 2.917E-05 |
|---|
| induction of apoptosis by intracellular signals | GO:0008629 | | 6.161E-08 | 2.75E-05 |
|---|
| cyclin-dependent protein kinase regulator activity | GO:0016538 | | 1.122E-07 | 4.451E-05 |
|---|
| regulation of cyclin-dependent protein kinase activity | GO:0000079 | | 1.145E-07 | 4.09E-05 |
|---|
| release of cytochrome c from mitochondria | GO:0001836 | | 2.471E-07 | 8.02E-05 |
|---|
Parker_GPL887 file
| Name | Accession Number | Link | P-val | Corrected P-val |
|---|
| protein serine/threonine kinase inhibitor activity | GO:0030291 | | 1.081E-09 | 3.943E-06 |
|---|
| keratinocyte differentiation | GO:0030216 | | 1.249E-09 | 2.278E-06 |
|---|
| epidermal cell differentiation | GO:0009913 | | 1.988E-09 | 2.418E-06 |
|---|
| protein kinase inhibitor activity | GO:0004860 | | 2.725E-08 | 2.485E-05 |
|---|
| kinase inhibitor activity | GO:0019210 | | 3.075E-08 | 2.243E-05 |
|---|
| induction of apoptosis by intracellular signals | GO:0008629 | | 5.925E-08 | 3.603E-05 |
|---|
| negative regulation of cyclin-dependent protein kinase activity | GO:0045736 | | 8.92E-08 | 4.648E-05 |
|---|
| cyclin-dependent protein kinase inhibitor activity | GO:0004861 | | 8.92E-08 | 4.067E-05 |
|---|
| negative regulation of caspase activity | GO:0043154 | | 1.226E-07 | 4.968E-05 |
|---|
| regulation of cyclin-dependent protein kinase activity | GO:0000079 | | 1.453E-07 | 5.302E-05 |
|---|
| midbody | GO:0030496 | | 1.633E-07 | 5.417E-05 |
|---|
Pawitan_GPL96-GPL97 file
| Name | Accession Number | Link | P-val | Corrected P-val |
|---|
| keratinocyte differentiation | GO:0030216 | | 2.015E-12 | 4.848E-09 |
|---|
| epidermal cell differentiation | GO:0009913 | | 4.184E-12 | 5.033E-09 |
|---|
| negative regulation of cyclin-dependent protein kinase activity | GO:0045736 | | 9.588E-08 | 7.69E-05 |
|---|
| induction of apoptosis by intracellular signals | GO:0008629 | | 1.005E-07 | 6.044E-05 |
|---|
| regulation of B cell proliferation | GO:0030888 | | 1.756E-07 | 8.448E-05 |
|---|
| regulation of cyclin-dependent protein kinase activity | GO:0000079 | | 2.643E-07 | 1.06E-04 |
|---|
| negative regulation of caspase activity | GO:0043154 | | 2.901E-07 | 9.971E-05 |
|---|
| release of cytochrome c from mitochondria | GO:0001836 | | 2.901E-07 | 8.725E-05 |
|---|
| negative regulation of protein kinase activity | GO:0006469 | | 5.094E-07 | 1.362E-04 |
|---|
| negative regulation of kinase activity | GO:0033673 | | 5.409E-07 | 1.301E-04 |
|---|
| negative regulation of peptidase activity | GO:0010466 | | 5.409E-07 | 1.183E-04 |
|---|
| Name | Accession Number | Link | P-val | Corrected P-val |
|---|
| keratinocyte differentiation | GO:0030216 | | 7.063E-12 | 1.624E-08 |
|---|
| epidermal cell differentiation | GO:0009913 | | 1.662E-11 | 1.912E-08 |
|---|
| negative regulation of cyclin-dependent protein kinase activity | GO:0045736 | | 1.44E-07 | 1.104E-04 |
|---|
| induction of apoptosis by intracellular signals | GO:0008629 | | 2.87E-07 | 1.651E-04 |
|---|
| regulation of B cell proliferation | GO:0030888 | | 3.08E-07 | 1.417E-04 |
|---|
| regulation of cyclin-dependent protein kinase activity | GO:0000079 | | 7.766E-07 | 2.977E-04 |
|---|
| negative regulation of caspase activity | GO:0043154 | | 9.306E-07 | 3.058E-04 |
|---|
| release of cytochrome c from mitochondria | GO:0001836 | | 9.306E-07 | 2.676E-04 |
|---|
| negative regulation of protein kinase activity | GO:0006469 | | 1.221E-06 | 3.119E-04 |
|---|
| negative regulation of kinase activity | GO:0033673 | | 1.31E-06 | 3.012E-04 |
|---|
| negative regulation of transferase activity | GO:0051348 | | 1.606E-06 | 3.359E-04 |
|---|
Sotiriou file
| Name | Accession Number | Link | P-val | Corrected P-val |
|---|
| keratinocyte differentiation | GO:0030216 | | 7.063E-12 | 1.624E-08 |
|---|
| epidermal cell differentiation | GO:0009913 | | 1.662E-11 | 1.912E-08 |
|---|
| negative regulation of cyclin-dependent protein kinase activity | GO:0045736 | | 1.44E-07 | 1.104E-04 |
|---|
| induction of apoptosis by intracellular signals | GO:0008629 | | 2.87E-07 | 1.651E-04 |
|---|
| regulation of B cell proliferation | GO:0030888 | | 3.08E-07 | 1.417E-04 |
|---|
| regulation of cyclin-dependent protein kinase activity | GO:0000079 | | 7.766E-07 | 2.977E-04 |
|---|
| negative regulation of caspase activity | GO:0043154 | | 9.306E-07 | 3.058E-04 |
|---|
| release of cytochrome c from mitochondria | GO:0001836 | | 9.306E-07 | 2.676E-04 |
|---|
| negative regulation of protein kinase activity | GO:0006469 | | 1.221E-06 | 3.119E-04 |
|---|
| negative regulation of kinase activity | GO:0033673 | | 1.31E-06 | 3.012E-04 |
|---|
| negative regulation of transferase activity | GO:0051348 | | 1.606E-06 | 3.359E-04 |
|---|
Van-De-Vijver file
| Name | Accession Number | Link | P-val | Corrected P-val |
|---|
| keratinocyte differentiation | GO:0030216 | | 7.104E-08 | 1.309E-04 |
|---|
| epidermal cell differentiation | GO:0009913 | | 1.089E-07 | 1.003E-04 |
|---|
| release of cytochrome c from mitochondria | GO:0001836 | | 1.696E-07 | 1.042E-04 |
|---|
| apoptotic mitochondrial changes | GO:0008637 | | 3.627E-07 | 1.671E-04 |
|---|
| striated muscle cell differentiation | GO:0051146 | | 1.369E-06 | 5.047E-04 |
|---|
| epidermal growth factor receptor signaling pathway | GO:0007173 | | 2.449E-06 | 7.524E-04 |
|---|
| induction of apoptosis by intracellular signals | GO:0008629 | | 7.75E-06 | 2.04E-03 |
|---|
| response to insulin stimulus | GO:0032868 | | 7.75E-06 | 1.785E-03 |
|---|
| epidermis development | GO:0008544 | | 1.002E-05 | 2.053E-03 |
|---|
| ectoderm development | GO:0007398 | | 1.232E-05 | 2.271E-03 |
|---|
| muscle cell differentiation | GO:0042692 | | 1.771E-05 | 2.968E-03 |
|---|
| Name | Accession Number | Link | P-val | Corrected P-val |
|---|
| keratinocyte differentiation | GO:0030216 | | 7.063E-12 | 1.624E-08 |
|---|
| epidermal cell differentiation | GO:0009913 | | 1.662E-11 | 1.912E-08 |
|---|
| negative regulation of cyclin-dependent protein kinase activity | GO:0045736 | | 1.44E-07 | 1.104E-04 |
|---|
| induction of apoptosis by intracellular signals | GO:0008629 | | 2.87E-07 | 1.651E-04 |
|---|
| regulation of B cell proliferation | GO:0030888 | | 3.08E-07 | 1.417E-04 |
|---|
| regulation of cyclin-dependent protein kinase activity | GO:0000079 | | 7.766E-07 | 2.977E-04 |
|---|
| negative regulation of caspase activity | GO:0043154 | | 9.306E-07 | 3.058E-04 |
|---|
| release of cytochrome c from mitochondria | GO:0001836 | | 9.306E-07 | 2.676E-04 |
|---|
| negative regulation of protein kinase activity | GO:0006469 | | 1.221E-06 | 3.119E-04 |
|---|
| negative regulation of kinase activity | GO:0033673 | | 1.31E-06 | 3.012E-04 |
|---|
| negative regulation of transferase activity | GO:0051348 | | 1.606E-06 | 3.359E-04 |
|---|
| Name | Accession Number | Link | P-val | Corrected P-val |
|---|
| keratinocyte differentiation | GO:0030216 | | 9.903E-12 | 2.35E-08 |
|---|
| epidermal cell differentiation | GO:0009913 | | 2.224E-11 | 2.639E-08 |
|---|
| negative regulation of cyclin-dependent protein kinase activity | GO:0045736 | | 1.393E-07 | 1.102E-04 |
|---|
| induction of apoptosis by intracellular signals | GO:0008629 | | 3.39E-07 | 2.011E-04 |
|---|
| regulation of B cell proliferation | GO:0030888 | | 7.08E-07 | 3.36E-04 |
|---|
| regulation of cyclin-dependent protein kinase activity | GO:0000079 | | 8.775E-07 | 3.471E-04 |
|---|
| negative regulation of caspase activity | GO:0043154 | | 9.003E-07 | 3.052E-04 |
|---|
| release of cytochrome c from mitochondria | GO:0001836 | | 1.124E-06 | 3.335E-04 |
|---|
| negative regulation of protein kinase activity | GO:0006469 | | 1.657E-06 | 4.37E-04 |
|---|
| negative regulation of peptidase activity | GO:0010466 | | 1.677E-06 | 3.98E-04 |
|---|
| negative regulation of kinase activity | GO:0033673 | | 1.768E-06 | 3.814E-04 |
|---|
