Study run-a2
Study informations
103 subnetworks in total page | file
306 genes associated page | file
Enriched GO terms page
General informations
General Index page
Study Index page
Subnetwork 4486-5-real
score
| Dataset | Score | P-val 1 | P-val 2 | P-val 3 |
| Desmedt | 0.1660 | 1.972e-02 | 1.616e-02 | 1.478e-01 |
| IPC-NIBC-129 | 0.2658 | 1.975e-02 | 2.946e-02 | 2.304e-01 |
| Ivshina_GPL96-GPL97 | 0.2167 | 7.915e-03 | 1.344e-02 | 2.391e-01 |
| Loi_GPL570 | 0.2137 | 9.724e-02 | 1.086e-01 | 3.618e-01 |
| Loi_GPL96-GPL97 | 0.1685 | 1.000e-06 | 1.100e-05 | 1.000e-06 |
| Parker_GPL1390 | 0.2506 | 5.990e-02 | 7.377e-02 | 4.341e-01 |
| Parker_GPL887 | 0.0165 | 4.417e-01 | 4.608e-01 | 4.928e-01 |
| Pawitan_GPL96-GPL97 | 0.4064 | 9.626e-01 | 9.531e-01 | 1.000e+00 |
| Schmidt | 0.2303 | 1.176e-02 | 1.310e-02 | 1.612e-01 |
| Sotiriou | 0.2782 | 2.129e-02 | 1.667e-02 | 2.860e-01 |
| Van-De-Vijver | 0.3241 | 1.980e-03 | 2.846e-03 | 9.191e-02 |
| Zhang | 0.3029 | 1.182e-01 | 7.501e-02 | 2.526e-01 |
| Zhou | 0.3821 | 4.336e-02 | 3.131e-02 | 2.806e-01 |
Expression data for subnetwork 4486-5-real in each dataset
Desmedt |
IPC-NIBC-129 |
Ivshina_GPL96-GPL97 |
Loi_GPL570 |
Loi_GPL96-GPL97 |
Parker_GPL1390 |
Parker_GPL887 |
Pawitan_GPL96-GPL97 |
Schmidt |
Sotiriou |
Van-De-Vijver |
Zhang |
Zhou |
Subnetwork structure for each dataset
- Desmedt

Score for each gene in subnetwork 4486-5-real in each dataset
| Gene Symbol | Links | Frequency | Frequency Rank | Subnetwork score rank | Global rank |
Desmedt | IPC-NIBC-129 | Ivshina_GPL96-GPL97 | Loi_GPL570 | Loi_GPL96-GPL97 | Parker_GPL1390 | Parker_GPL887 | Pawitan_GPL96-GPL97 | Schmidt | Sotiriou | Van-De-Vijver | Zhang | Zhou |
| pcna |  | 15 | 11 | 110 | 85 | 0.096 | 0.202 | 0.109 | 0.180 | 0.118 | 0.119 | 0.104 | 0.256 | 0.151 | 0.059 | 0.201 | 0.123 | 0.233 |
| fen1 |  | 9 | 22 | 133 | 112 | 0.045 | 0.194 | 0.169 | 0.196 | 0.136 | 0.252 | 0.033 | 0.332 | 0.221 | 0.144 | 0.242 | 0.056 | 0.114 |
| cttn |  | 10 | 20 | 1 | 6 | 0.067 | 0.065 | 0.123 | 0.238 | 0.126 | 0.263 | -0.172 | 0.216 | 0.069 | 0.115 | undef | 0.025 | 0.279 |
| tle1 |  | 47 | 6 | 1 | 3 | 0.062 | 0.235 | -0.032 | -0.177 | 0.033 | 0.085 | 0.339 | 0.068 | 0.126 | -0.027 | 0.170 | 0.068 | 0.025 |
| bat2 |  | 3 | 62 | 74 | 68 | 0.039 | 0.182 | -0.001 | -0.013 | 0.062 | undef | -0.335 | 0.109 | 0.186 | 0.099 | undef | 0.059 | 0.146 |
| ccnb1 |  | 42 | 8 | 56 | 39 | 0.082 | 0.246 | 0.212 | 0.224 | 0.256 | 0.099 | 0.126 | 0.351 | 0.129 | 0.249 | undef | 0.167 | 0.398 |
| mst1r |  | 1 | 116 | 229 | 233 | -0.069 | 0.101 | 0.052 | -0.112 | 0.050 | 0.025 | 0.005 | 0.065 | 0.073 | -0.041 | 0.144 | 0.267 | 0.308 |
| ccnd1 |  | 92 | 2 | 18 | 12 | 0.127 | -0.183 | 0.062 | 0.190 | 0.157 | -0.002 | -0.190 | 0.105 | -0.107 | 0.174 | undef | 0.144 | 0.290 |
| cdc2 |  | 96 | 1 | 1 | 1 | 0.073 | 0.247 | 0.206 | 0.172 | 0.247 | 0.153 | -0.131 | 0.282 | 0.226 | 0.221 | 0.162 | 0.297 | 0.336 |
| p4ha2 |  | 3 | 62 | 74 | 68 | 0.077 | 0.313 | 0.070 | 0.159 | 0.149 | 0.216 | 0.056 | 0.180 | 0.055 | 0.105 | 0.211 | 0.043 | 0.237 |
| grb2 |  | 9 | 22 | 1 | 7 | 0.084 | -0.013 | 0.086 | -0.031 | 0.162 | -0.038 | 0.003 | 0.065 | 0.158 | 0.127 | 0.149 | 0.194 | -0.005 |
GO Enrichment output for subnetwork 4486-5-real in each dataset
| Name | Accession Number | Link | P-val | Corrected P-val |
| response to UV | GO:0009411 |  | 2.535E-05 | 0.05831021 |
| positive regulation of cyclin-dependent protein kinase activity | GO:0045737 |  | 3.163E-05 | 0.03637014 |
| anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | GO:0031145 |  | 5.938E-05 | 0.04552214 |
| positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle | GO:0051437 |  | 6.235E-05 | 0.03584839 |
| UV protection | GO:0009650 |  | 6.762E-05 | 0.03110314 |
| positive regulation of ubiquitin-protein ligase activity | GO:0051443 |  | 7.183E-05 | 0.02753452 |
| regulation of ubiquitin-protein ligase activity during mitotic cell cycle | GO:0051439 |  | 7.183E-05 | 0.02360101 |
| positive regulation of ligase activity | GO:0051351 |  | 8.588E-05 | 0.02469003 |
| phosphoinositide-mediated signaling | GO:0048015 |  | 9.353E-05 | 0.02390197 |
| regulation of ubiquitin-protein ligase activity | GO:0051438 |  | 9.353E-05 | 0.02151178 |
| regulation of ligase activity | GO:0051340 |  | 1.101E-04 | 0.02302916 |
IPC-NIBC-129 file
| Name | Accession Number | Link | P-val | Corrected P-val |
| response to UV | GO:0009411 |  | 7.871E-06 | 0.01922812 |
| positive regulation of cyclin-dependent protein kinase activity | GO:0045737 |  | 1.326E-05 | 0.01620161 |
| anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | GO:0031145 |  | 1.494E-05 | 0.01217 |
| positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle | GO:0051437 |  | 1.562E-05 | 9.538E-03 |
| positive regulation of ubiquitin-protein ligase activity | GO:0051443 |  | 1.775E-05 | 8.674E-03 |
| regulation of ubiquitin-protein ligase activity during mitotic cell cycle | GO:0051439 |  | 1.775E-05 | 7.228E-03 |
| phosphoinositide-mediated signaling | GO:0048015 |  | 2.007E-05 | 7.005E-03 |
| positive regulation of ligase activity | GO:0051351 |  | 2.172E-05 | 6.634E-03 |
| regulation of ubiquitin-protein ligase activity | GO:0051438 |  | 2.346E-05 | 6.368E-03 |
| UV protection | GO:0009650 |  | 2.602E-05 | 6.357E-03 |
| regulation of ligase activity | GO:0051340 |  | 2.82E-05 | 6.264E-03 |
Ivshina_GPL96-GPL97 file
| Name | Accession Number | Link | P-val | Corrected P-val |
| response to UV | GO:0009411 |  | 1.152E-05 | 0.02770657 |
| positive regulation of cyclin-dependent protein kinase activity | GO:0045737 |  | 1.847E-05 | 0.02221462 |
| anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | GO:0031145 |  | 2.443E-05 | 0.01959618 |
| positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle | GO:0051437 |  | 2.553E-05 | 0.01535678 |
| positive regulation of ubiquitin-protein ligase activity | GO:0051443 |  | 2.901E-05 | 0.01396152 |
| regulation of ubiquitin-protein ligase activity during mitotic cell cycle | GO:0051439 |  | 2.901E-05 | 0.0116346 |
| phosphoinositide-mediated signaling | GO:0048015 |  | 3.28E-05 | 0.01127244 |
| positive regulation of ligase activity | GO:0051351 |  | 3.549E-05 | 0.01067333 |
| UV protection | GO:0009650 |  | 3.622E-05 | 9.682E-03 |
| regulation of ubiquitin-protein ligase activity | GO:0051438 |  | 3.832E-05 | 9.221E-03 |
| regulation of ligase activity | GO:0051340 |  | 4.605E-05 | 0.01007252 |
Loi_GPL570 file
| Name | Accession Number | Link | P-val | Corrected P-val |
| response to UV | GO:0009411 |  | 7.871E-06 | 0.01922812 |
| positive regulation of cyclin-dependent protein kinase activity | GO:0045737 |  | 1.326E-05 | 0.01620161 |
| anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | GO:0031145 |  | 1.494E-05 | 0.01217 |
| positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle | GO:0051437 |  | 1.562E-05 | 9.538E-03 |
| positive regulation of ubiquitin-protein ligase activity | GO:0051443 |  | 1.775E-05 | 8.674E-03 |
| regulation of ubiquitin-protein ligase activity during mitotic cell cycle | GO:0051439 |  | 1.775E-05 | 7.228E-03 |
| phosphoinositide-mediated signaling | GO:0048015 |  | 2.007E-05 | 7.005E-03 |
| positive regulation of ligase activity | GO:0051351 |  | 2.172E-05 | 6.634E-03 |
| regulation of ubiquitin-protein ligase activity | GO:0051438 |  | 2.346E-05 | 6.368E-03 |
| UV protection | GO:0009650 |  | 2.602E-05 | 6.357E-03 |
| regulation of ligase activity | GO:0051340 |  | 2.82E-05 | 6.264E-03 |
Loi_GPL96-GPL97 file
| Name | Accession Number | Link | P-val | Corrected P-val |
| response to UV | GO:0009411 |  | 1.152E-05 | 0.02770657 |
| positive regulation of cyclin-dependent protein kinase activity | GO:0045737 |  | 1.847E-05 | 0.02221462 |
| anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | GO:0031145 |  | 2.443E-05 | 0.01959618 |
| positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle | GO:0051437 |  | 2.553E-05 | 0.01535678 |
| positive regulation of ubiquitin-protein ligase activity | GO:0051443 |  | 2.901E-05 | 0.01396152 |
| regulation of ubiquitin-protein ligase activity during mitotic cell cycle | GO:0051439 |  | 2.901E-05 | 0.0116346 |
| phosphoinositide-mediated signaling | GO:0048015 |  | 3.28E-05 | 0.01127244 |
| positive regulation of ligase activity | GO:0051351 |  | 3.549E-05 | 0.01067333 |
| UV protection | GO:0009650 |  | 3.622E-05 | 9.682E-03 |
| regulation of ubiquitin-protein ligase activity | GO:0051438 |  | 3.832E-05 | 9.221E-03 |
| regulation of ligase activity | GO:0051340 |  | 4.605E-05 | 0.01007252 |
Parker_GPL1390 file
| Name | Accession Number | Link | P-val | Corrected P-val |
| cyclin-dependent protein kinase holoenzyme complex | GO:0000307 |  | 1.259E-08 | 4.494E-05 |
| response to UV | GO:0009411 |  | 4.081E-06 | 7.286E-03 |
| MutLalpha complex binding | GO:0032405 |  | 4.142E-06 | 4.93E-03 |
| ribonuclease H activity | GO:0004523 |  | 4.142E-06 | 3.697E-03 |
| endodeoxyribonuclease activity. producing 5'-phosphomonoesters | GO:0016888 |  | 4.142E-06 | 2.958E-03 |
| 5'-3' exonuclease activity | GO:0008409 |  | 4.142E-06 | 2.465E-03 |
| positive regulation of cyclin-dependent protein kinase activity | GO:0045737 |  | 6.21E-06 | 3.168E-03 |
| insulin receptor substrate binding | GO:0043560 |  | 6.21E-06 | 2.772E-03 |
| DNA replication factor C complex | GO:0005663 |  | 6.21E-06 | 2.464E-03 |
| exodeoxyribonuclease activity | GO:0004529 |  | 6.21E-06 | 2.218E-03 |
| procollagen-proline dioxygenase activity | GO:0019798 |  | 6.21E-06 | 2.016E-03 |
Parker_GPL887 file
| Name | Accession Number | Link | P-val | Corrected P-val |
| cyclin-dependent protein kinase holoenzyme complex | GO:0000307 |  | 1.462E-08 | 5.334E-05 |
| response to UV | GO:0009411 |  | 3.65E-06 | 6.658E-03 |
| ribonuclease H activity | GO:0004523 |  | 4.447E-06 | 5.407E-03 |
| endodeoxyribonuclease activity. producing 5'-phosphomonoesters | GO:0016888 |  | 4.447E-06 | 4.055E-03 |
| 5'-3' exonuclease activity | GO:0008409 |  | 4.447E-06 | 3.244E-03 |
| RNA polymerase II carboxy-terminal domain kinase activity | GO:0008353 |  | 4.447E-06 | 2.704E-03 |
| epidermal growth factor receptor binding | GO:0005154 |  | 4.447E-06 | 2.317E-03 |
| positive regulation of cyclin-dependent protein kinase activity | GO:0045737 |  | 6.667E-06 | 3.04E-03 |
| MutLalpha complex binding | GO:0032405 |  | 6.667E-06 | 2.702E-03 |
| DNA replication factor C complex | GO:0005663 |  | 6.667E-06 | 2.432E-03 |
| insulin receptor substrate binding | GO:0043560 |  | 9.33E-06 | 3.094E-03 |
Pawitan_GPL96-GPL97 file
| Name | Accession Number | Link | P-val | Corrected P-val |
| response to UV | GO:0009411 |  | 1.152E-05 | 0.02770657 |
| positive regulation of cyclin-dependent protein kinase activity | GO:0045737 |  | 1.847E-05 | 0.02221462 |
| anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | GO:0031145 |  | 2.443E-05 | 0.01959618 |
| positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle | GO:0051437 |  | 2.553E-05 | 0.01535678 |
| positive regulation of ubiquitin-protein ligase activity | GO:0051443 |  | 2.901E-05 | 0.01396152 |
| regulation of ubiquitin-protein ligase activity during mitotic cell cycle | GO:0051439 |  | 2.901E-05 | 0.0116346 |
| phosphoinositide-mediated signaling | GO:0048015 |  | 3.28E-05 | 0.01127244 |
| positive regulation of ligase activity | GO:0051351 |  | 3.549E-05 | 0.01067333 |
| UV protection | GO:0009650 |  | 3.622E-05 | 9.682E-03 |
| regulation of ubiquitin-protein ligase activity | GO:0051438 |  | 3.832E-05 | 9.221E-03 |
| regulation of ligase activity | GO:0051340 |  | 4.605E-05 | 0.01007252 |
| Name | Accession Number | Link | P-val | Corrected P-val |
| response to UV | GO:0009411 |  | 2.535E-05 | 0.05831021 |
| positive regulation of cyclin-dependent protein kinase activity | GO:0045737 |  | 3.163E-05 | 0.03637014 |
| anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | GO:0031145 |  | 5.938E-05 | 0.04552214 |
| positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle | GO:0051437 |  | 6.235E-05 | 0.03584839 |
| UV protection | GO:0009650 |  | 6.762E-05 | 0.03110314 |
| positive regulation of ubiquitin-protein ligase activity | GO:0051443 |  | 7.183E-05 | 0.02753452 |
| regulation of ubiquitin-protein ligase activity during mitotic cell cycle | GO:0051439 |  | 7.183E-05 | 0.02360101 |
| positive regulation of ligase activity | GO:0051351 |  | 8.588E-05 | 0.02469003 |
| phosphoinositide-mediated signaling | GO:0048015 |  | 9.353E-05 | 0.02390197 |
| regulation of ubiquitin-protein ligase activity | GO:0051438 |  | 9.353E-05 | 0.02151178 |
| regulation of ligase activity | GO:0051340 |  | 1.101E-04 | 0.02302916 |
Sotiriou file
| Name | Accession Number | Link | P-val | Corrected P-val |
| response to UV | GO:0009411 |  | 2.535E-05 | 0.05831021 |
| positive regulation of cyclin-dependent protein kinase activity | GO:0045737 |  | 3.163E-05 | 0.03637014 |
| anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | GO:0031145 |  | 5.938E-05 | 0.04552214 |
| positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle | GO:0051437 |  | 6.235E-05 | 0.03584839 |
| UV protection | GO:0009650 |  | 6.762E-05 | 0.03110314 |
| positive regulation of ubiquitin-protein ligase activity | GO:0051443 |  | 7.183E-05 | 0.02753452 |
| regulation of ubiquitin-protein ligase activity during mitotic cell cycle | GO:0051439 |  | 7.183E-05 | 0.02360101 |
| positive regulation of ligase activity | GO:0051351 |  | 8.588E-05 | 0.02469003 |
| phosphoinositide-mediated signaling | GO:0048015 |  | 9.353E-05 | 0.02390197 |
| regulation of ubiquitin-protein ligase activity | GO:0051438 |  | 9.353E-05 | 0.02151178 |
| regulation of ligase activity | GO:0051340 |  | 1.101E-04 | 0.02302916 |
Van-De-Vijver file
| Name | Accession Number | Link | P-val | Corrected P-val |
| phosphoinositide-mediated signaling | GO:0048015 |  | 8.988E-06 | 0.01656449 |
| UV protection | GO:0009650 |  | 1.859E-05 | 0.01713158 |
| nucleotide-excision repair. DNA gap filling | GO:0006297 |  | 6.885E-05 | 0.04229781 |
| negative regulation of Wnt receptor signaling pathway | GO:0030178 |  | 6.885E-05 | 0.03172336 |
| base-excision repair | GO:0006284 |  | 8.029E-05 | 0.02959411 |
| insulin receptor signaling pathway | GO:0008286 |  | 9.259E-05 | 0.02844208 |
| epidermal growth factor receptor signaling pathway | GO:0007173 |  | 1.347E-04 | 0.03547191 |
| single fertilization | GO:0007338 |  | 1.671E-04 | 0.03850645 |
| cellular response to insulin stimulus | GO:0032869 |  | 1.847E-04 | 0.03781255 |
| regulation of Wnt receptor signaling pathway | GO:0030111 |  | 2.03E-04 | 0.03741626 |
| fertilization | GO:0009566 |  | 2.423E-04 | 0.04060162 |
| Name | Accession Number | Link | P-val | Corrected P-val |
| response to UV | GO:0009411 |  | 2.535E-05 | 0.05831021 |
| positive regulation of cyclin-dependent protein kinase activity | GO:0045737 |  | 3.163E-05 | 0.03637014 |
| anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | GO:0031145 |  | 5.938E-05 | 0.04552214 |
| positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle | GO:0051437 |  | 6.235E-05 | 0.03584839 |
| UV protection | GO:0009650 |  | 6.762E-05 | 0.03110314 |
| positive regulation of ubiquitin-protein ligase activity | GO:0051443 |  | 7.183E-05 | 0.02753452 |
| regulation of ubiquitin-protein ligase activity during mitotic cell cycle | GO:0051439 |  | 7.183E-05 | 0.02360101 |
| positive regulation of ligase activity | GO:0051351 |  | 8.588E-05 | 0.02469003 |
| phosphoinositide-mediated signaling | GO:0048015 |  | 9.353E-05 | 0.02390197 |
| regulation of ubiquitin-protein ligase activity | GO:0051438 |  | 9.353E-05 | 0.02151178 |
| regulation of ligase activity | GO:0051340 |  | 1.101E-04 | 0.02302916 |
| Name | Accession Number | Link | P-val | Corrected P-val |
| response to UV | GO:0009411 |  | 2.119E-05 | 0.05028748 |
| positive regulation of cyclin-dependent protein kinase activity | GO:0045737 |  | 2.677E-05 | 0.03176494 |
| UV protection | GO:0009650 |  | 5.725E-05 | 0.04528274 |
| anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | GO:0031145 |  | 5.895E-05 | 0.03497402 |
| positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle | GO:0051437 |  | 7.031E-05 | 0.03336908 |
| positive regulation of ubiquitin-protein ligase activity | GO:0051443 |  | 7.971E-05 | 0.03152378 |
| regulation of ubiquitin-protein ligase activity during mitotic cell cycle | GO:0051439 |  | 7.971E-05 | 0.02702038 |
| phosphoinositide-mediated signaling | GO:0048015 |  | 8.989E-05 | 0.02666306 |
| positive regulation of ligase activity | GO:0051351 |  | 8.989E-05 | 0.02370049 |
| regulation of ubiquitin-protein ligase activity | GO:0051438 |  | 1.009E-04 | 0.02393996 |
| regulation of ligase activity | GO:0051340 |  | 1.127E-04 | 0.02431782 |