pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-a2/out-0.05-06-0.01-300-run-a2//th1-pval-1e-01-11-th2-pval-1e-02-02-th3-pval-1e-01-02-run-a2/go_data/4486-5-real-Van-De-Vijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! phosphoinositide-mediated signaling GO:0048015 45 45 2,000 8,988E-06 0,01656449 ! UV protection GO:0009650 7 7 1,000 1,859E-05 0,01713158 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 1,000 6,885E-05 0,04229781 ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 1,000 6,885E-05 0,03172336 ! base-excision repair GO:0006284 14 14 1,000 8,029E-05 0,02959411 ! insulin receptor signaling pathway GO:0008286 17 15 1,000 9,259E-05 0,02844208 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 1,000 1,347E-04 0,03547191 ! single fertilization GO:0007338 21 20 1,000 1,671E-04 0,03850645 ! cellular response to insulin stimulus GO:0032869 23 21 1,000 1,847E-04 0,03781255 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 1,000 2,03E-04 0,03741626 ! fertilization GO:0009566 25 24 1,000 2,423E-04 0,04060162 ! double-strand break repair GO:0006302 27 26 1,000 2,851E-04 0,04378321 ! response to insulin stimulus GO:0032868 28 26 1,000 2,851E-04 0,04041527 ! response to UV GO:0009411 29 29 1,000 3,556E-04 0,0468135 ! regulation of DNA replication GO:0006275 32 31 1,000 4,069E-04 0,04999346 ! response to peptide hormone stimulus GO:0043434 36 34 1,000 4,902E-04 0,05646273 ! nucleotide-excision repair GO:0006289 40 39 1,000 6,459E-04 0,07002191 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 1,000 7,494E-04 0,07672953 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 1,000 8,226E-04 0,07978983 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 1,000 8,604E-04 0,07928742 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 1,000 8,991E-04 0,07890584 ! positive regulation of ligase activity GO:0051351 47 46 1,000 8,991E-04 0,07531921 ! cellular response to hormone stimulus GO:0032870 48 46 1,000 8,991E-04 0,07204447 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 1,000 9,789E-04 0,07517337 ! regulation of ligase activity GO:0051340 50 49 1,000 1,02E-03 0,0752008 ! regulation of DNA metabolic process GO:0051052 51 50 1,000 1,062E-03 0,07528473 ! response to light stimulus GO:0009416 53 52 1,000 1,149E-03 0,07839744 ! proteasomal protein catabolic process GO:0010498 62 61 1,000 1,578E-03 0,10387607 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! Ras protein signal transduction GO:0007265 69 67 1,000 1,901E-03 0,12082208 ! response to radiation GO:0009314 70 68 1,000 1,958E-03 0,12027541 ! negative regulation of signal transduction GO:0009968 71 71 1,000 2,133E-03 0,12678722 ! negative regulation of cell communication GO:0010648 76 76 1,000 2,44E-03 0,14052366 ! DNA replication GO:0006260 91 91 1,000 3,48E-03 0,19436783 ! anti-apoptosis GO:0006916 100 99 1,000 4,107E-03 0,22261022 ! response to hormone stimulus GO:0009725 102 100 1,000 4,189E-03 0,22055576 ! rRNA transcription GO:0009303 5 5 0,000 5,078E-03 0,25998287 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 5,078E-03 0,2529563 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 5,078E-03 0,24629956 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 5,078E-03 0,23998419 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 5,078E-03 0,23398458 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 5,078E-03 0,22827764 ! reproductive cellular process GO:0048610 5 5 0,000 5,078E-03 0,22284246 ! positive regulation of glucose metabolic process GO:0010907 5 5 0,000 5,078E-03 0,21766008 ! negative regulation of blood pressure GO:0045776 6 5 0,000 5,078E-03 0,21271326 ! prostate gland development GO:0030850 5 5 0,000 5,078E-03 0,20798629 ! metencephalon development GO:0022037 5 5 0,000 5,078E-03 0,20346485 ! water transport GO:0006833 5 5 0,000 5,078E-03 0,19913581 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 5,078E-03 0,19498715 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 5,078E-03 0,19100782 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 5,078E-03 0,18718766 ! glycerol metabolic process GO:0006071 5 5 0,000 5,078E-03 0,18351732 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 5,078E-03 0,17998814 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 5,078E-03 0,17659214 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 5,078E-03 0,17332191 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 5,078E-03 0,1701706 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 5,078E-03 0,16713184 ! filopodium assembly GO:0046847 7 5 0,000 5,078E-03 0,16419971 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 5,078E-03 0,16136868 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 5,078E-03 0,15863361 ! GTP metabolic process GO:0046039 5 5 0,000 5,078E-03 0,15598972 ! establishment of tissue polarity GO:0007164 5 5 0,000 5,078E-03 0,15343251 ! mRNA stabilization GO:0048255 5 5 0,000 5,078E-03 0,15095779 GO:0043489|RNA stabilization, ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 5,078E-03 0,14856164 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 5,078E-03 0,14624036 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 5,078E-03 0,14399051 ! social behavior GO:0035176 5 5 0,000 5,078E-03 0,14180884 ! macrophage chemotaxis GO:0048246 6 5 0,000 5,078E-03 0,13969229 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 5,078E-03 0,13763799 ! memory GO:0007613 5 5 0,000 5,078E-03 0,13564324 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 5,078E-03 0,13370547 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 5,078E-03 0,1318223 ! membrane hyperpolarization GO:0060081 5 5 0,000 5,078E-03 0,12999143 ! response to lipid GO:0033993 5 5 0,000 5,078E-03 0,12821073 ! erythrocyte maturation GO:0043249 5 5 0,000 5,078E-03 0,12647815 ! hippocampus development GO:0021766 6 5 0,000 5,078E-03 0,12479178 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 5,078E-03 0,12314978 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 5,078E-03 0,12155043 ! middle ear morphogenesis GO:0042474 5 5 0,000 5,078E-03 0,11999209 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 5,078E-03 0,11847321 ! mechanosensory behavior GO:0007638 5 5 0,000 5,078E-03 0,11699229 ! heart looping GO:0001947 5 5 0,000 5,078E-03 0,11554794 ! negative regulation of endocytosis GO:0045806 5 5 0,000 5,078E-03 0,11413882 ! response to interferon-gamma GO:0034341 5 5 0,000 5,078E-03 0,11276365 ! pseudouridine synthesis GO:0001522 5 5 0,000 5,078E-03 0,11142123 ! endocrine pancreas development GO:0031018 5 5 0,000 5,078E-03 0,11011039 ! pH reduction GO:0045851 5 5 0,000 5,078E-03 0,10883004 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 5,078E-03 0,10757912 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 5,078E-03 0,10635663 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 5,078E-03 0,10516161 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 5,078E-03 0,10399315 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 5,078E-03 0,10285037 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 5,078E-03 0,10173243 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 5,078E-03 0,10063853 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 5,078E-03 0,09956791 ! adrenal gland development GO:0030325 5 5 0,000 5,078E-03 0,09851982 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 5,078E-03 0,09749358 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 5,078E-03 0,09648849 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 5,078E-03 0,09550391 ! astrocyte differentiation GO:0048708 5 5 0,000 5,078E-03 0,09453922 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 5,078E-03 0,09359383 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 5,078E-03 0,09266716 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 5,078E-03 0,09175866 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 5,078E-03 0,0908678 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 5,078E-03 0,08999407 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 5,078E-03 0,08913698 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 5,078E-03 0,08829607 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 5,078E-03 0,08747087 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 5,078E-03 0,08666096 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 5,078E-03 0,0858659 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 5,078E-03 0,0850853 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 5,078E-03 0,08431877 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 5,078E-03 0,08356592 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 5,078E-03 0,0828264 ! response to ATP GO:0033198 5 5 0,000 5,078E-03 0,08209985 ! regulation of type I interferon production GO:0032479 5 5 0,000 5,078E-03 0,08138594 ! regulation of appetite GO:0032098 5 5 0,000 5,078E-03 0,08068434 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 5,078E-03 0,07999473 ! paraxial mesoderm development GO:0048339 5 5 0,000 5,078E-03 0,07931681 ! regulation of phospholipase A2 activity GO:0032429 5 5 0,000 5,078E-03 0,07865028 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 5,078E-03 0,07799486 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 5,078E-03 0,07735027 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 5,078E-03 0,07671626 ! receptor clustering GO:0043113 5 5 0,000 5,078E-03 0,07609255 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 5,078E-03 0,0754789 ! fear response GO:0042596 5 5 0,000 5,078E-03 0,07487507 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 5,078E-03 0,07428082 ! lens development in camera-type eye GO:0002088 5 5 0,000 5,078E-03 0,07369593 ! retinol metabolic process GO:0042572 5 5 0,000 5,078E-03 0,07312018 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 5,078E-03 0,07255336 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 5,078E-03 0,07199526 ! positive regulation of exocytosis GO:0045921 6 5 0,000 5,078E-03 0,07144567 ! parturition GO:0007567 5 5 0,000 5,078E-03 0,07090442 ! cellular glucose homeostasis GO:0001678 5 5 0,000 5,078E-03 0,0703713 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 5,078E-03 0,06984614 ! Schwann cell differentiation GO:0014037 5 5 0,000 5,078E-03 0,06932876 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 5,078E-03 0,06881899 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 5,078E-03 0,06831667 ! protein heterooligomerization GO:0051291 5 5 0,000 5,078E-03 0,06782162 ! regulation of gliogenesis GO:0014013 5 5 0,000 5,078E-03 0,06733369 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 5,078E-03 0,06685274 ! response to UV-B GO:0010224 5 5 0,000 5,078E-03 0,0663786 ! oligodendrocyte development GO:0014003 5 5 0,000 5,078E-03 0,06591115 ! hyaluronan metabolic process GO:0030212 5 5 0,000 5,078E-03 0,06545023 ! activated T cell proliferation GO:0050798 5 5 0,000 5,078E-03 0,06499572 ! interaction with symbiont GO:0051702 5 5 0,000 5,078E-03 0,06454747 ! cellular extravasation GO:0045123 5 5 0,000 5,078E-03 0,06410536 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 5,078E-03 0,06366927 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 5,078E-03 0,06323908 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 5,078E-03 0,06281465 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 5,078E-03 0,06239589 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 5,078E-03 0,06198267 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 5,078E-03 0,06157489 ! response to amine stimulus GO:0014075 5 5 0,000 5,078E-03 0,06117244 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 5,078E-03 0,06077522 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 5,078E-03 0,06038312 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 5,078E-03 0,05999605 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 5,078E-03 0,05961391 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 5,078E-03 0,0592366 ! neuron recognition GO:0008038 5 5 0,000 5,078E-03 0,05886405 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 5,078E-03 0,05849615 ! decidualization GO:0046697 5 5 0,000 5,078E-03 0,05813282 ! hair follicle maturation GO:0048820 5 5 0,000 5,078E-03 0,05777397 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 5,078E-03 0,05741953 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 5,078E-03 0,05706941 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 5,078E-03 0,05672353 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 5,078E-03 0,05638183 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 5,078E-03 0,05604421 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 5,078E-03 0,05571061 ! postreplication repair GO:0006301 5 5 0,000 5,078E-03 0,05538097 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 5,078E-03 0,0550552 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 5,078E-03 0,05473324 ! histone methylation GO:0016571 5 5 0,000 5,078E-03 0,05441502 ! DNA methylation GO:0006306 5 5 0,000 5,078E-03 0,05410048 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 5,078E-03 0,05378956 ! T cell lineage commitment GO:0002360 5 5 0,000 5,078E-03 0,05348219 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 5,078E-03 0,05317831 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 5,078E-03 0,05287787 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 5,078E-03 0,0525808 ! intracellular cholesterol transport GO:0032367 5 5 0,000 5,078E-03 0,05228706 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 5,078E-03 0,05199657 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 5,078E-03 0,0517093 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 5,078E-03 0,05142518 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 5,078E-03 0,05114417 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 5,078E-03 0,05086621 ! sterol catabolic process GO:0016127 5 5 0,000 5,078E-03 0,05059126 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 5,078E-03 0,05031926 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 5,078E-03 0,05005018 ! detection of biotic stimulus GO:0009595 5 5 0,000 5,078E-03 0,04978395 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 5,078E-03 0,04952055 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 5,078E-03 0,04925991 ! zymogen activation GO:0031638 5 5 0,000 5,078E-03 0,04900201 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 5,078E-03 0,04874679 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 5,078E-03 0,04849421 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 5,078E-03 0,04824424 ! peptidyl-lysine modification GO:0018205 5 5 0,000 5,078E-03 0,04799684 ! negative regulation of neuroblast proliferation GO:0007406 5 5 0,000 5,078E-03 0,04775196 ! peptidyl-histidine modification GO:0018202 5 5 0,000 5,078E-03 0,04750956 ! nucleosome positioning GO:0016584 5 5 0,000 5,078E-03 0,04726961 ! regulation of isotype switching GO:0045191 5 5 0,000 5,078E-03 0,04703208 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 5,078E-03 0,04679692 ! negative regulation of neurological system process GO:0031645 5 5 0,000 5,078E-03 0,0465641 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 5,078E-03 0,04633358 ! glutathione biosynthetic process GO:0006750 5 5 0,000 5,078E-03 0,04610534 ! NADPH regeneration GO:0006740 5 5 0,000 5,078E-03 0,04587933 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 5,078E-03 0,04565553 ! positive regulation of epidermis development GO:0045684 5 5 0,000 5,078E-03 0,0454339 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 5,078E-03 0,04521441 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 5,078E-03 0,04499703 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 5,078E-03 0,04478174 ! sarcomere organization GO:0045214 5 5 0,000 5,078E-03 0,04456849 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 5,078E-03 0,04435727 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 5,078E-03 0,04414803 ! negative regulation of glucose transport GO:0010829 5 5 0,000 5,078E-03 0,04394077 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 5,078E-03 0,04373544 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 5,078E-03 0,04353202 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 5,078E-03 0,04333048 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 5,078E-03 0,0431308 ! spleen development GO:0048536 5 5 0,000 5,078E-03 0,04293295 ! male genitalia development GO:0030539 5 5 0,000 5,078E-03 0,04273691 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 5,078E-03 0,04254265 ! quaternary ammonium group transport GO:0015697 5 5 0,000 5,078E-03 0,04235015 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 5,078E-03 0,04215938 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 5,078E-03 0,04197033 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 5,078E-03 0,04178296 ! removal of superoxide radicals GO:0019430 6 5 0,000 5,078E-03 0,04159726 ! myeloid cell homeostasis GO:0002262 5 5 0,000 5,078E-03 0,0414132 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 5,078E-03 0,04123076 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 5,078E-03 0,04104993 ! ATP catabolic process GO:0006200 5 5 0,000 5,078E-03 0,04087067 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 5,078E-03 0,04069297 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 5,078E-03 0,04051681 ! blastocyst formation GO:0001825 5 5 0,000 5,078E-03 0,04034217 ! regulation of fibrinolysis GO:0051917 5 5 0,000 5,078E-03 0,04016903 ! embryonic gut development GO:0048566 5 5 0,000 5,078E-03 0,03999736 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 5,078E-03 0,03982716 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 5,078E-03 0,0396584 ! activation of innate immune response GO:0002218 5 5 0,000 5,078E-03 0,03949107 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 5,078E-03 0,03932514 ! catecholamine transport GO:0051937 5 5 0,000 5,078E-03 0,0391606 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 5,078E-03 0,03899743 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 5,078E-03 0,03883562 ! muscle adaptation GO:0043500 5 5 0,000 5,078E-03 0,03867514 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 5,078E-03 0,03851598 ! embryonic heart tube development GO:0035050 5 5 0,000 5,078E-03 0,03835813 ! cardiac cell differentiation GO:0035051 6 5 0,000 5,078E-03 0,03820156 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 5,078E-03 0,03804627 ! defense response to fungus GO:0050832 5 5 0,000 5,078E-03 0,03789224 ! lysogeny GO:0030069 5 5 0,000 5,078E-03 0,03773945 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 5,078E-03 0,03758788 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 5,078E-03 0,03743753 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 5,078E-03 0,03728838 ! response to nicotine GO:0035094 5 5 0,000 5,078E-03 0,03714041 ! establishment of cell polarity GO:0030010 5 5 0,000 5,078E-03 0,03699361 ! mitochondrion localization GO:0051646 5 5 0,000 5,078E-03 0,03684797 ! nucleus localization GO:0051647 5 5 0,000 5,078E-03 0,03670346 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 5,078E-03 0,03656009 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 6,091E-03 0,04368235 ! axon extension GO:0048675 7 6 0,000 6,091E-03 0,04351303 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 6,091E-03 0,04334503 ! N-terminal protein amino acid modification GO:0031365 6 6 0,000 6,091E-03 0,04317832 GO:0018409|peptide or protein amino-terminal blocking, ! tRNA modification GO:0006400 6 6 0,000 6,091E-03 0,04301288 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 6,091E-03 0,04284871 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 6,091E-03 0,04268579 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 6,091E-03 0,0425241 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 6,091E-03 0,04236363 ! virus-host interaction GO:0019048 6 6 0,000 6,091E-03 0,04220437 ! regulation of S phase GO:0033261 6 6 0,000 6,091E-03 0,0420463 ! myotube differentiation GO:0014902 6 6 0,000 6,091E-03 0,04188941 ! regulation of B cell proliferation GO:0030888 6 6 0,000 6,091E-03 0,04173369 ! bone remodeling GO:0046849 6 6 0,000 6,091E-03 0,04157912 ! N-glycan processing GO:0006491 6 6 0,000 6,091E-03 0,04142569 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 6,091E-03 0,04127339 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 6,091E-03 0,04112221 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 6,091E-03 0,04097213 ! retina development in camera-type eye GO:0060041 6 6 0,000 6,091E-03 0,04082314 ! RNA methylation GO:0001510 6 6 0,000 6,091E-03 0,04067523 ! cartilage condensation GO:0001502 7 6 0,000 6,091E-03 0,04052839 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 6,091E-03 0,0403826 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 6,091E-03 0,04023786 GO:0050927|positive regulation of positive chemotaxis, ! succinate metabolic process GO:0006105 7 6 0,000 6,091E-03 0,04009415 ! artery development GO:0060840 6 6 0,000 6,091E-03 0,03995147 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 6,091E-03 0,0398098 ! bile acid metabolic process GO:0008206 6 6 0,000 6,091E-03 0,03966913 ! androgen metabolic process GO:0008209 6 6 0,000 6,091E-03 0,03952945 ! estrogen metabolic process GO:0008210 6 6 0,000 6,091E-03 0,03939075 ! limbic system development GO:0021761 7 6 0,000 6,091E-03 0,03925302 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 6,091E-03 0,03911625 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 0,000 6,091E-03 0,03898043 ! positive regulation of heart contraction GO:0045823 6 6 0,000 6,091E-03 0,03884555 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 6,091E-03 0,0387116 ! pathogenesis GO:0009405 6 6 0,000 6,091E-03 0,03857857 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 6,091E-03 0,03844645 ! positive regulation of cell growth GO:0030307 6 6 0,000 6,091E-03 0,03831523 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 6,091E-03 0,03818491 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 6,091E-03 0,03805547 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 6,091E-03 0,0379269 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 6,091E-03 0,0377992 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 6,091E-03 0,03767236 ! arginine metabolic process GO:0006525 6 6 0,000 6,091E-03 0,03754636 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 6,091E-03 0,03742121 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 6,091E-03 0,03729689 ! glutamate catabolic process GO:0006538 7 6 0,000 6,091E-03 0,03717339 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 6,091E-03 0,0370507 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 6,091E-03 0,03692882 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 6,091E-03 0,03680775 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 6,091E-03 0,03668746 ! ER overload response GO:0006983 6 6 0,000 6,091E-03 0,03656796 ! V(D)J recombination GO:0033151 6 6 0,000 6,091E-03 0,03644923 ! focal adhesion formation GO:0048041 7 6 0,000 6,091E-03 0,03633127 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 6,091E-03 0,03621407 ! negative regulation of T cell proliferation GO:0042130 6 6 0,000 6,091E-03 0,03609763 GO:0070667|negative regulation of mast cell proliferation, ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 6,091E-03 0,03598193 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 6,091E-03 0,03586697 ! regulation of heart rate GO:0002027 6 6 0,000 6,091E-03 0,03575275 ! lipid digestion GO:0044241 6 6 0,000 6,091E-03 0,03563925 ! asymmetric protein localization GO:0008105 6 6 0,000 6,091E-03 0,03552646 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 6,091E-03 0,03541439 ! phagocytosis, engulfment GO:0006911 6 6 0,000 6,091E-03 0,03530303 ! Rac protein signal transduction GO:0016601 6 6 0,000 6,091E-03 0,03519236 ! regulation of vascular permeability GO:0043114 6 6 0,000 6,091E-03 0,03508238 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 6,091E-03 0,03497309 ! ruffle organization GO:0031529 6 6 0,000 6,091E-03 0,03486448 ! peptidyl-serine phosphorylation GO:0018105 6 6 0,000 6,091E-03 0,03475654 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 6,091E-03 0,03464927 ! retinoic acid metabolic process GO:0042573 6 6 0,000 6,091E-03 0,03454265 ! neutral amino acid transport GO:0015804 6 6 0,000 6,091E-03 0,0344367 ! L-amino acid transport GO:0015807 6 6 0,000 6,091E-03 0,03433138 ! bone mineralization GO:0030282 6 6 0,000 6,091E-03 0,03422672 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 6,091E-03 0,03412268 ! negative regulation of ossification GO:0030279 6 6 0,000 6,091E-03 0,03401928 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 6,091E-03 0,0339165 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of bone resorption GO:0045124 6 6 0,000 6,091E-03 0,03381435 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 6,091E-03 0,0337128 ! purine base biosynthetic process GO:0009113 6 6 0,000 6,091E-03 0,03361186 ! G1 DNA damage checkpoint GO:0031571 6 6 0,000 6,091E-03 0,03351153 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 6,091E-03 0,03341179 ! regulation of phagocytosis GO:0050764 6 6 0,000 6,091E-03 0,03331265 ! regulation of organ growth GO:0046620 6 6 0,000 6,091E-03 0,03321409 ! regulation of circadian rhythm GO:0042752 6 6 0,000 6,091E-03 0,03311611 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 6,091E-03 0,03301871 ! response to dsRNA GO:0043331 6 6 0,000 6,091E-03 0,03292188 ! DNA unwinding during replication GO:0006268 6 6 0,000 6,091E-03 0,03282562 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 6,091E-03 0,03272992 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! regulation of T cell differentiation in the thymus GO:0033081 6 6 0,000 6,091E-03 0,03263478 ! genitalia development GO:0048806 6 6 0,000 6,091E-03 0,03254018 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 6,091E-03 0,03244614 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 6,091E-03 0,03235263 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 0,000 6,091E-03 0,03225966 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 6,091E-03 0,03216723 ! multicellular organismal aging GO:0010259 6 6 0,000 6,091E-03 0,03207532 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 6,091E-03 0,03198394 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 6,091E-03 0,03189308 ! erythrocyte development GO:0048821 6 6 0,000 6,091E-03 0,03180273 ! renal water homeostasis GO:0003091 6 6 0,000 6,091E-03 0,03171289 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 6,091E-03 0,03162356 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 6,091E-03 0,03153473 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 6,091E-03 0,03144639 ! ribosome assembly GO:0042255 6 6 0,000 6,091E-03 0,03135856 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 6,091E-03 0,03127121 ! diencephalon development GO:0021536 6 6 0,000 6,091E-03 0,03118434 ! fucose catabolic process GO:0019317 6 6 0,000 6,091E-03 0,03109796 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 6,091E-03 0,03101205 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 6,091E-03 0,03092662 ! regulation of lipid transport GO:0032368 6 6 0,000 6,091E-03 0,03084166 ! regulation of cell division GO:0051302 6 6 0,000 6,091E-03 0,03075716 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 6,091E-03 0,03067312 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 6,091E-03 0,03058954 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 6,091E-03 0,03050642 ! salivary gland morphogenesis GO:0007435 6 6 0,000 6,091E-03 0,03042375 ! neuroblast proliferation GO:0007405 6 6 0,000 6,091E-03 0,03034152 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 6,091E-03 0,03025974 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 6,091E-03 0,03017839 ! regulation of glucose transport GO:0010827 6 6 0,000 6,091E-03 0,03009749 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 6,091E-03 0,03001701 ! methionine biosynthetic process GO:0009086 6 6 0,000 6,091E-03 0,02993697 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 6,091E-03 0,02985735 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 6,091E-03 0,02977815 ! thymus development GO:0048538 6 6 0,000 6,091E-03 0,02969937 ! lymph node development GO:0048535 6 6 0,000 6,091E-03 0,02962101 ! organic cation transport GO:0015695 6 6 0,000 6,091E-03 0,02954306 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 6,091E-03 0,02946552 ! regulation of RNA splicing GO:0043484 6 6 0,000 6,091E-03 0,02938838 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 0,000 6,091E-03 0,02931165 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! positive regulation of JNK cascade GO:0046330 7 6 0,000 6,091E-03 0,02923532 ! sperm-egg recognition GO:0035036 7 6 0,000 6,091E-03 0,02915938 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 6,091E-03 0,02908384 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 6,091E-03 0,02900869 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 6,091E-03 0,02893392 ! alditol metabolic process GO:0019400 6 6 0,000 6,091E-03 0,02885954 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 6,091E-03 0,02878555 ! regulation of amino acid transport GO:0051955 6 6 0,000 6,091E-03 0,02871193 ! maternal placenta development GO:0001893 6 6 0,000 6,091E-03 0,02863868 ! regulation of embryonic development GO:0045995 6 6 0,000 6,091E-03 0,02856581 ! negative regulation of immune effector process GO:0002698 6 6 0,000 6,091E-03 0,02849331 ! localization within membrane GO:0051668 6 6 0,000 6,091E-03 0,02842117 ! respiratory burst GO:0045730 7 7 0,000 7,103E-03 0,03305988 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 7,103E-03 0,03297661 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 7,103E-03 0,03289375 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 7,103E-03 0,03281131 ! positive regulation of blood pressure GO:0045777 7 7 0,000 7,103E-03 0,03272928 ! positive regulation of cellular catabolic process GO:0031331 7 7 0,000 7,103E-03 0,03264766 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 7,103E-03 0,03256645 ! regulation of chemokine production GO:0032642 7 7 0,000 7,103E-03 0,03248564 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 7,103E-03 0,03240523 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 7,103E-03 0,03232522 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 7,103E-03 0,0322456 ! cellular protein complex disassembly GO:0043624 8 7 0,000 7,103E-03 0,03216637 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 7,103E-03 0,03208753 ! gene silencing by RNA GO:0031047 7 7 0,000 7,103E-03 0,03200908 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 7,103E-03 0,03193101 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 7,103E-03 0,03185332 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 7,103E-03 0,031776 ! keratinocyte proliferation GO:0043616 7 7 0,000 7,103E-03 0,03169906 ! axis specification GO:0009798 7 7 0,000 7,103E-03 0,03162249 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 7,103E-03 0,0315463 ! visual behavior GO:0007632 7 7 0,000 7,103E-03 0,03147046 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 7,103E-03 0,03139499 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 7,103E-03 0,03131989 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 7,103E-03 0,03124514 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 7,103E-03 0,03117074 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 7,103E-03 0,0310967 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 7,103E-03 0,03102302 ! endothelial cell differentiation GO:0045446 7 7 0,000 7,103E-03 0,03094968 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 7,103E-03 0,03087668 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 7,103E-03 0,03080403 ! digestive system development GO:0055123 7 7 0,000 7,103E-03 0,03073172 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 7,103E-03 0,03065975 ! regulation of exit from mitosis GO:0007096 7 7 0,000 7,103E-03 0,03058811 ! protein targeting to ER GO:0045047 8 7 0,000 7,103E-03 0,03051681 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 7,103E-03 0,03044584 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 7,103E-03 0,0303752 ! endoderm development GO:0007492 7 7 0,000 7,103E-03 0,03030489 ! regulation of defense response to virus GO:0050688 7 7 0,000 7,103E-03 0,0302349 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 7,103E-03 0,03016524 GO:0006688|glycosphingolipid biosynthetic process, ! regulation of mRNA processing GO:0050684 7 7 0,000 7,103E-03 0,03009589 ! response to hexose stimulus GO:0009746 7 7 0,000 7,103E-03 0,03002686 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 7,103E-03 0,02995815 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 7,103E-03 0,02988976 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 7,103E-03 0,02982167 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 0,000 7,103E-03 0,02975389 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! cardiac muscle tissue development GO:0048738 7 7 0,000 7,103E-03 0,02968642 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 7,103E-03 0,02961926 ! complement activation, alternative pathway GO:0006957 7 7 0,000 7,103E-03 0,0295524 ! arachidonic acid secretion GO:0050482 7 7 0,000 7,103E-03 0,02948584 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 7,103E-03 0,02941958 ! response to X-ray GO:0010165 7 7 0,000 7,103E-03 0,02935362 ! regulation of intracellular pH GO:0051453 7 7 0,000 7,103E-03 0,02928795 ! DNA integration GO:0015074 7 7 0,000 7,103E-03 0,02922257 ! myofibril assembly GO:0030239 7 7 0,000 7,103E-03 0,02915749 GO:0055002|striated muscle cell development, ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 0,000 7,103E-03 0,02909269 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 7,103E-03 0,02902819 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 7,103E-03 0,02896397 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 7,103E-03 0,02890003 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 7,103E-03 0,02883637 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 7,103E-03 0,02877299 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 7,103E-03 0,0287099 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 7,103E-03 0,02864707 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 7,103E-03 0,02858453 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 7,103E-03 0,02852225 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 7,103E-03 0,02846025 ! axon cargo transport GO:0008088 7 7 0,000 7,103E-03 0,02839851 ! eating behavior GO:0042755 7 7 0,000 7,103E-03 0,02833704 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 7,103E-03 0,02827584 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 7,103E-03 0,0282149 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 7,103E-03 0,02815422 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 7,103E-03 0,0280938 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 7,103E-03 0,02803365 ! cranial nerve development GO:0021545 7 7 0,000 7,103E-03 0,02797375 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 7,103E-03 0,0279141 ! induction of an organ GO:0001759 7 7 0,000 7,103E-03 0,02785471 ! leukocyte activation during immune response GO:0002366 7 7 0,000 7,103E-03 0,02779557 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 7,103E-03 0,02773668 ! autonomic nervous system development GO:0048483 7 7 0,000 7,103E-03 0,02767804 ! intracellular lipid transport GO:0032365 7 7 0,000 7,103E-03 0,02761965 ! detection of chemical stimulus GO:0009593 8 7 0,000 7,103E-03 0,0275615 ! platelet activation GO:0030168 8 7 0,000 7,103E-03 0,0275036 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 7,103E-03 0,02744594 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 7,103E-03 0,02738852 ! natural killer cell activation GO:0030101 7 7 0,000 7,103E-03 0,02733134 ! response to gamma radiation GO:0010332 8 7 0,000 7,103E-03 0,0272744 ! NADP metabolic process GO:0006739 7 7 0,000 7,103E-03 0,0272177 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 7,103E-03 0,02716123 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 7,103E-03 0,027105 ! ubiquinone metabolic process GO:0006743 7 7 0,000 7,103E-03 0,02704899 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 7,103E-03 0,02699322 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 7,103E-03 0,02693768 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 7,103E-03 0,02688237 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 7,103E-03 0,02682728 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 7,103E-03 0,02677242 ! regulation of ATPase activity GO:0043462 7 7 0,000 7,103E-03 0,02671778 ! cell-cell recognition GO:0009988 8 7 0,000 7,103E-03 0,02666337 ! hormone catabolic process GO:0042447 7 7 0,000 7,103E-03 0,02660917 ! dopamine metabolic process GO:0042417 7 7 0,000 7,103E-03 0,0265552 ! cAMP biosynthetic process GO:0006171 7 7 0,000 7,103E-03 0,02650144 ! oxygen transport GO:0015671 7 7 0,000 7,103E-03 0,0264479 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 7,103E-03 0,02639458 ! regulation of mRNA stability GO:0043488 7 7 0,000 7,103E-03 0,02634147 ! biogenic amine catabolic process GO:0042402 7 7 0,000 7,103E-03 0,02628858 ! regulation of axon extension GO:0030516 7 7 0,000 7,103E-03 0,0262359 ! cell killing GO:0001906 7 7 0,000 7,103E-03 0,02618343 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 7,103E-03 0,02613116 ! adult feeding behavior GO:0008343 7 7 0,000 7,103E-03 0,02607911 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 7,103E-03 0,02602726 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 7,103E-03 0,02597562 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 7,103E-03 0,02592418 ! negative regulation of T cell activation GO:0050868 7 7 0,000 7,103E-03 0,02587295 ! response to cold GO:0009409 7 7 0,000 7,103E-03 0,02582192 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 8,115E-03 0,02943983 ! negative regulation of muscle development GO:0048635 8 8 0,000 8,115E-03 0,02938199 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 8,115E-03 0,02932438 ! positive regulation of translation GO:0045727 8 8 0,000 8,115E-03 0,02926699 ! positive regulation of cell killing GO:0031343 8 8 0,000 8,115E-03 0,02920983 ! superoxide anion generation GO:0042554 8 8 0,000 8,115E-03 0,02915289 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 8,115E-03 0,02909618 ! cGMP metabolic process GO:0046068 8 8 0,000 8,115E-03 0,02903968 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 8,115E-03 0,0289834 ! 'de novo' protein folding GO:0006458 8 8 0,000 8,115E-03 0,02892734 ! dicarboxylic acid transport GO:0006835 8 8 0,000 8,115E-03 0,02887149 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 8,115E-03 0,02881587 ! negative regulation of bone remodeling GO:0046851 8 8 0,000 8,115E-03 0,02876045 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 8,115E-03 0,02870525 ! zinc ion transport GO:0006829 8 8 0,000 8,115E-03 0,02865026 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 8,115E-03 0,02859548 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 8,115E-03 0,02854091 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 8,115E-03 0,02848654 ! cardiac muscle contraction GO:0060048 8 8 0,000 8,115E-03 0,02843238 ! lipid localization GO:0010876 8 8 0,000 8,115E-03 0,02837843 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 8,115E-03 0,02832469 ! response to cAMP GO:0051591 8 8 0,000 8,115E-03 0,02827114 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 8,115E-03 0,0282178 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 8,115E-03 0,02816466 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 8,115E-03 0,02811172 ! negative regulation of ion transport GO:0043271 8 8 0,000 8,115E-03 0,02805898 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 8,115E-03 0,02800643 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 8,115E-03 0,02795408 ! sensory perception of taste GO:0050909 8 8 0,000 8,115E-03 0,02790193 ! organelle fusion GO:0048284 8 8 0,000 8,115E-03 0,02784997 ! pancreas development GO:0031016 8 8 0,000 8,115E-03 0,0277982 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 8,115E-03 0,02774663 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 8,115E-03 0,02769525 ! negative regulation of proteolysis GO:0045861 8 8 0,000 8,115E-03 0,02764406 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 8,115E-03 0,02759305 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 8,115E-03 0,02754224 ! sperm motility GO:0030317 8 8 0,000 8,115E-03 0,02749161 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 8,115E-03 0,02744116 ! DNA duplex unwinding GO:0032508 8 8 0,000 8,115E-03 0,02739091 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 8,115E-03 0,02734083 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 8,115E-03 0,02729094 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 8,115E-03 0,02724123 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 8,115E-03 0,0271917 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 8,115E-03 0,02714235 ! Golgi organization GO:0007030 8 8 0,000 8,115E-03 0,02709318 ! cell-cell junction assembly GO:0007043 8 8 0,000 8,115E-03 0,02704418 ! regulation of stress fiber formation GO:0051492 9 8 0,000 8,115E-03 0,02699537 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 8,115E-03 0,02694673 ! fructose metabolic process GO:0006000 8 8 0,000 8,115E-03 0,02689826 ! mannose metabolic process GO:0006013 9 8 0,000 8,115E-03 0,02684997 ! NAD metabolic process GO:0019674 8 8 0,000 8,115E-03 0,02680185 ! sex determination GO:0007530 8 8 0,000 8,115E-03 0,02675391 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 8,115E-03 0,02670613 ! plasma membrane fusion GO:0045026 8 8 0,000 8,115E-03 0,02665853 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 0,000 8,115E-03 0,02661109 ! response to fungus GO:0009620 8 8 0,000 8,115E-03 0,02656383 ! stem cell differentiation GO:0048863 8 8 0,000 8,115E-03 0,02651673 ! alpha-beta T cell activation GO:0046631 8 8 0,000 8,115E-03 0,0264698 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 8,115E-03 0,02642303 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 8,115E-03 0,02637643 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 8,115E-03 0,02632999 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 8,115E-03 0,02628372 ! regulation of vasodilation GO:0042312 8 8 0,000 8,115E-03 0,0262376 ! vasoconstriction GO:0042310 8 8 0,000 8,115E-03 0,02619165 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 8,115E-03 0,02614586 ! muscle cell development GO:0055001 8 8 0,000 8,115E-03 0,02610023 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 8,115E-03 0,02605476 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 8,115E-03 0,02600945 ! sensory perception of pain GO:0019233 8 8 0,000 8,115E-03 0,0259643 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 8,115E-03 0,0259193 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 8,115E-03 0,02587445 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 8,115E-03 0,02582977 ! chromatin silencing GO:0006342 8 8 0,000 8,115E-03 0,02578523 ! tissue regeneration GO:0042246 8 8 0,000 8,115E-03 0,02574085 ! salivary gland development GO:0007431 8 8 0,000 8,115E-03 0,02569662 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 8,115E-03 0,02565255 ! T cell homeostasis GO:0043029 8 8 0,000 8,115E-03 0,02560862 ! peptide biosynthetic process GO:0043043 9 8 0,000 8,115E-03 0,02556484 ! peptidyl-serine modification GO:0018209 8 8 0,000 8,115E-03 0,02552122 ! water homeostasis GO:0030104 8 8 0,000 8,115E-03 0,02547774 ! cofactor transport GO:0051181 8 8 0,000 8,115E-03 0,02543441 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 8,115E-03 0,02539123 ! acid secretion GO:0046717 8 8 0,000 8,115E-03 0,02534819 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 8,115E-03 0,0253053 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 8,115E-03 0,02526256 ! protein-chromophore linkage GO:0018298 9 8 0,000 8,115E-03 0,02521996 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 8,115E-03 0,0251775 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 8,115E-03 0,02513518 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 8,115E-03 0,02509301 ! regulation of RNA stability GO:0043487 8 8 0,000 8,115E-03 0,02505098 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 8,115E-03 0,02500909 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 0,000 8,115E-03 0,02496734 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 8,115E-03 0,02492572 ! release of cytochrome c from mitochondria GO:0001836 9 8 0,000 8,115E-03 0,02488425 ! regulation of organic acid transport GO:0032890 8 8 0,000 8,115E-03 0,02484291 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 8,115E-03 0,02480172 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 8,115E-03 0,02476065 ! regulation of multi-organism process GO:0043900 8 8 0,000 8,115E-03 0,02471973 ! positive regulation of amine transport GO:0051954 8 8 0,000 8,115E-03 0,02467893 ! developmental induction GO:0031128 8 8 0,000 8,115E-03 0,02463828 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 8,115E-03 0,02459775 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 8,115E-03 0,02455736 ! actin filament polymerization GO:0030041 9 8 0,000 8,115E-03 0,02451711 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 8,115E-03 0,02447698 ! peptide hormone processing GO:0016486 8 8 0,000 8,115E-03 0,02443698 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 8,115E-03 0,02439712 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 8,115E-03 0,02435738 ! lactation GO:0007595 10 9 0,000 9,125E-03 0,02734557 ! embryonic pattern specification GO:0009880 10 9 0,000 9,125E-03 0,02730118 ! positive regulation of cell size GO:0045793 9 9 0,000 9,125E-03 0,02725693 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 9,125E-03 0,02721283 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 9,125E-03 0,02716887 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 9,125E-03 0,02712505 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 9,125E-03 0,02708137 ! negative regulation of cell cycle process GO:0010948 9 9 0,000 9,125E-03 0,02703783 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 0,000 9,125E-03 0,02699443 ! viral genome replication GO:0019079 9 9 0,000 9,125E-03 0,02695117 ! phospholipid catabolic process GO:0009395 9 9 0,000 9,125E-03 0,02690805 ! copper ion transport GO:0006825 9 9 0,000 9,125E-03 0,02686506 ! lipid phosphorylation GO:0046834 9 9 0,000 9,125E-03 0,02682221 ! aminoglycan catabolic process GO:0006026 9 9 0,000 9,125E-03 0,0267795 ! Golgi vesicle budding GO:0048194 9 9 0,000 9,125E-03 0,02673693 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 9,125E-03 0,02669449 ! RNA polyadenylation GO:0043631 9 9 0,000 9,125E-03 0,02665218 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 9,125E-03 0,02661001 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 9,125E-03 0,02656798 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 9,125E-03 0,02652607 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 9,125E-03 0,0264843 ! phospholipid efflux GO:0033700 9 9 0,000 9,125E-03 0,02644265 ! response to alkaloid GO:0043279 10 9 0,000 9,125E-03 0,02640114 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 9,125E-03 0,02635976 ! cytokine biosynthetic process GO:0042089 9 9 0,000 9,125E-03 0,02631851 GO:0042107|cytokine metabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 9 9 0,000 9,125E-03 0,02627739 ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 9,125E-03 0,02623639 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 9,125E-03 0,02619553 ! response to ethanol GO:0045471 9 9 0,000 9,125E-03 0,02615479 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 0,000 9,125E-03 0,02611417 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 9,125E-03 0,02607369 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 9,125E-03 0,02603333 ! methionine metabolic process GO:0006555 9 9 0,000 9,125E-03 0,02599309 ! glutamine metabolic process GO:0006541 9 9 0,000 9,125E-03 0,02595298 ! cerebral cortex development GO:0021987 9 9 0,000 9,125E-03 0,02591299 ! response to osmotic stress GO:0006970 9 9 0,000 9,125E-03 0,02587312 ! pigmentation during development GO:0048066 9 9 0,000 9,125E-03 0,02583338 ! reverse cholesterol transport GO:0043691 9 9 0,000 9,125E-03 0,02579376 ! central nervous system neuron development GO:0021954 10 9 0,000 9,125E-03 0,02575426 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 9,125E-03 0,02571488 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 9,125E-03 0,02567562 ! substrate-bound cell migration GO:0006929 9 9 0,000 9,125E-03 0,02563648 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 9,125E-03 0,02559746 ! negative regulation of caspase activity GO:0043154 9 9 0,000 9,125E-03 0,02555855 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 9,125E-03 0,02551977 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 9,125E-03 0,0254811 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 9,125E-03 0,02544255 ! regulation of dephosphorylation GO:0035303 9 9 0,000 9,125E-03 0,02540412 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 9,125E-03 0,0253658 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 9,125E-03 0,0253276 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 9,125E-03 0,02528952 ! behavioral interaction between organisms GO:0051705 9 9 0,000 9,125E-03 0,02525154 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 9,125E-03 0,02521369 ! positive regulation of protein import into nucleus GO:0042307 9 9 0,000 9,125E-03 0,02517594 ! DNA replication initiation GO:0006270 9 9 0,000 9,125E-03 0,02513831 ! prostaglandin metabolic process GO:0006693 9 9 0,000 9,125E-03 0,02510079 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 9,125E-03 0,02506338 ! regulation of cellular pH GO:0030641 9 9 0,000 9,125E-03 0,02502608 ! histone acetylation GO:0016573 9 9 0,000 9,125E-03 0,0249889 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 9,125E-03 0,02495182 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 9,125E-03 0,02491486 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 9,125E-03 0,024878 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 9,125E-03 0,02484125 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 9,125E-03 0,02480461 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 9,125E-03 0,02476808 ! negative regulation of tissue remodeling GO:0034104 9 9 0,000 9,125E-03 0,02473166 ! negative regulation of protein secretion GO:0050709 9 9 0,000 9,125E-03 0,02469534 ! regulation of leukocyte migration GO:0002685 9 9 0,000 9,125E-03 0,02465913 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 9,125E-03 0,02462303 ! collagen catabolic process GO:0030574 9 9 0,000 9,125E-03 0,02458703 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 9,125E-03 0,02455114 ! purine base metabolic process GO:0006144 9 9 0,000 9,125E-03 0,02451535 ! gas transport GO:0015669 9 9 0,000 9,125E-03 0,02447966 ! cholesterol efflux GO:0033344 9 9 0,000 9,125E-03 0,02444408 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 9,125E-03 0,0244086 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 9,125E-03 0,02437323 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 9,125E-03 0,02433796 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 9,125E-03 0,02430279 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 0,000 9,125E-03 0,02426772 ! defense response to virus GO:0051607 9 9 0,000 9,125E-03 0,02423275 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 9,125E-03 0,02419788 ! actin filament-based movement GO:0030048 9 9 0,000 9,125E-03 0,02416312 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 9,125E-03 0,02412845 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,01013456 0,02675931 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,01013456 0,02672103 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,01013456 0,02668285 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,01013456 0,02664479 ! regulation of glucose metabolic process GO:0010906 10 10 0,000 0,01013456 0,02660683 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,01013456 0,02656899 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,01013456 0,02653125 ! neuron maturation GO:0042551 10 10 0,000 0,01013456 0,02649361 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,01013456 0,02645609 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,01013456 0,02641867 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,01013456 0,02638135 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,01013456 0,02634414 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,01013456 0,02630704 ! hormone secretion GO:0046879 10 10 0,000 0,01013456 0,02627004 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,01013456 0,02623314 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,01013456 0,02619635 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 0,000 0,01013456 0,02615966 ! inositol metabolic process GO:0006020 10 10 0,000 0,01013456 0,02612307 ! cAMP metabolic process GO:0046058 10 10 0,000 0,01013456 0,02608659 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,01013456 0,0260502 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,01013456 0,02601392 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,01013456 0,02597774 ! glial cell development GO:0021782 10 10 0,000 0,01013456 0,02594166 ! phototransduction GO:0007602 11 10 0,000 0,01013456 0,02590568 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,01013456 0,0258698 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,01013456 0,02583402 ! apoptotic mitochondrial changes GO:0008637 11 10 0,000 0,01013456 0,02579834 ! fat cell differentiation GO:0045444 10 10 0,000 0,01013456 0,02576275 ! myoblast differentiation GO:0045445 10 10 0,000 0,01013456 0,02572727 ! centrosome cycle GO:0007098 10 10 0,000 0,01013456 0,02569188 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,01013456 0,02565659 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,01013456 0,02562139 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,01013456 0,0255863 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,01013456 0,0255513 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,01013456 0,02551639 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,01013456 0,02548158 ! protein polyubiquitination GO:0000209 10 10 0,000 0,01013456 0,02544686 ! glutamate metabolic process GO:0006536 11 10 0,000 0,01013456 0,02541224 ! plasma membrane organization GO:0007009 10 10 0,000 0,01013456 0,02537771 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,01013456 0,02534328 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-substrate junction assembly GO:0007044 11 10 0,000 0,01013456 0,02530894 ! lysosomal transport GO:0007041 10 10 0,000 0,01013456 0,02527469 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,01013456 0,02524054 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,01013456 0,02520647 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,01013456 0,0251725 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,01013456 0,02513862 ! exocrine system development GO:0035272 10 10 0,000 0,01013456 0,02510483 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,01013456 0,02507114 ! neuromuscular junction development GO:0007528 10 10 0,000 0,01013456 0,02503753 ! embryo implantation GO:0007566 11 10 0,000 0,01013456 0,02500401 ! regulation of protein binding GO:0043393 11 10 0,000 0,01013456 0,02497058 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,01013456 0,02493725 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,01013456 0,024904 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,01013456 0,02487083 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,01013456 0,02483776 ! protein export from nucleus GO:0006611 10 10 0,000 0,01013456 0,02480478 ! negative regulation of immune response GO:0050777 10 10 0,000 0,01013456 0,02477188 ! cytolysis GO:0019835 10 10 0,000 0,01013456 0,02473907 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,01013456 0,02470634 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,01013456 0,02467371 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,01013456 0,02464116 ! histone deacetylation GO:0016575 10 10 0,000 0,01013456 0,02460869 ! mRNA splice site selection GO:0006376 11 10 0,000 0,01013456 0,02457631 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,01013456 0,02454402 ! gland morphogenesis GO:0022612 10 10 0,000 0,01013456 0,02451181 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,01013456 0,02447968 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,01013456 0,02444764 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,01013456 0,02441568 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,01013456 0,02438381 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,01013456 0,02435202 ! regulation of epidermis development GO:0045682 10 10 0,000 0,01013456 0,02432031 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,01013456 0,02428868 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,01013456 0,02425714 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,01013456 0,02422568 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,01013456 0,0241943 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,01013456 0,024163 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,01013456 0,02413178 ! nerve development GO:0021675 10 10 0,000 0,01013456 0,02410064 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 0,01013456 0,02406958 ! gut development GO:0048565 10 10 0,000 0,01013456 0,02403861 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,01013456 0,02400771 ! positive regulation of neuron apoptosis GO:0043525 10 10 0,000 0,01013456 0,02397689 ! negative regulation of homeostatic process GO:0032845 10 10 0,000 0,01013456 0,02394615 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,01013456 0,02391549 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,01013456 0,02388491 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,01013456 0,0238544 ! protein stabilization GO:0050821 10 10 0,000 0,01013456 0,02382398 ! protein secretion GO:0009306 11 11 0,000 0,01114316 0,02616158 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,01114316 0,0261283 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,01114316 0,0260951 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,01114316 0,02606198 ! negative regulation of defense response GO:0031348 11 11 0,000 0,01114316 0,02602895 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,01114316 0,025996 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,01114316 0,02596314 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,01114316 0,02593035 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,01114316 0,02589765 ! skin development GO:0043588 11 11 0,000 0,01114316 0,02586504 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,01114316 0,0258325 ! signal complex assembly GO:0007172 11 11 0,000 0,01114316 0,02580005 ! microtubule-based transport GO:0010970 11 11 0,000 0,01114316 0,02576768 ! endothelial cell migration GO:0043542 11 11 0,000 0,01114316 0,02573539 ! peroxisomal transport GO:0043574 11 11 0,000 0,01114316 0,02570318 ! protein amino acid methylation GO:0006479 11 11 0,000 0,01114316 0,02567105 GO:0008213|protein amino acid alkylation, ! protein amino acid acetylation GO:0006473 11 11 0,000 0,01114316 0,025639 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 0,000 0,01114316 0,02560703 GO:0032388|positive regulation of intracellular transport, ! heart contraction GO:0060047 11 11 0,000 0,01114316 0,02557514 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,01114316 0,02554333 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,01114316 0,0255116 ! T cell proliferation GO:0042098 11 11 0,000 0,01114316 0,02547995 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,01114316 0,02544838 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,01114316 0,02541688 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,01114316 0,02538546 ! spinal cord development GO:0021510 11 11 0,000 0,01114316 0,02535412 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,01114316 0,02532286 ! smooth muscle contraction GO:0006939 11 11 0,000 0,01114316 0,02529168 ! cellular response to starvation GO:0009267 11 11 0,000 0,01114316 0,02526057 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 0,000 0,01114316 0,02522953 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,01114316 0,02519858 ! digestive system process GO:0022600 11 11 0,000 0,01114316 0,0251677 ! mitotic spindle organization GO:0007052 11 11 0,000 0,01114316 0,02513689 ! fucose metabolic process GO:0006004 11 11 0,000 0,01114316 0,02510616 ! membrane budding GO:0006900 11 11 0,000 0,01114316 0,02507551 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,01114316 0,02504493 ! monoamine transport GO:0015844 11 11 0,000 0,01114316 0,02501442 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,01114316 0,02498399 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,01114316 0,02495363 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 0,000 0,01114316 0,02492335 ! body fluid secretion GO:0007589 11 11 0,000 0,01114316 0,02489314 ! G1/S transition checkpoint GO:0031575 12 11 0,000 0,01114316 0,024863 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,01114316 0,02483294 ! intermediate filament-based process GO:0045103 11 11 0,000 0,01114316 0,02480295 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,01114316 0,02477303 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 11 11 0,000 0,01114316 0,02474318 ! membrane depolarization GO:0051899 11 11 0,000 0,01114316 0,02471341 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,01114316 0,0246837 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,01114316 0,02465407 ! regulation of monooxygenase activity GO:0032768 11 11 0,000 0,01114316 0,02462451 ! oogenesis GO:0048477 11 11 0,000 0,01114316 0,02459502 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,01114316 0,0245656 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,01114316 0,02453625 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 0,000 0,01114316 0,02450697 GO:0006109|regulation of carbohydrate metabolic process, ! vitamin transport GO:0051180 11 11 0,000 0,01114316 0,02447776 ! muscle maintenance GO:0046716 12 11 0,000 0,01114316 0,02444862 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,01114316 0,02441955 ! hindbrain development GO:0030902 11 11 0,000 0,01114316 0,02439055 ! steroid catabolic process GO:0006706 11 11 0,000 0,01114316 0,02436161 ! endocrine process GO:0050886 11 11 0,000 0,01114316 0,02433275 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,01114316 0,02430395 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,01114316 0,02427522 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,01114316 0,02424656 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,01114316 0,02421797 ! negative regulation of lymphocyte activation GO:0051250 11 11 0,000 0,01114316 0,02418945 ! positive regulation of protein catabolic process GO:0045732 12 12 0,000 0,01215087 0,02634595 ! translational initiation GO:0006413 12 12 0,000 0,01215087 0,02631499 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,01215087 0,02628411 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,01215087 0,02625329 ! initiation of viral infection GO:0019059 12 12 0,000 0,01215087 0,02622255 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,01215087 0,02619188 ! iron ion transport GO:0006826 13 12 0,000 0,01215087 0,02616128 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,01215087 0,02613076 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,01215087 0,0261003 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,01215087 0,02606992 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,01215087 0,0260396 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,01215087 0,02600936 ! collagen metabolic process GO:0032963 12 12 0,000 0,01215087 0,02597919 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,01215087 0,02594908 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,01215087 0,02591905 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,01215087 0,02588909 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,01215087 0,02585919 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,01215087 0,02582937 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,01215087 0,02579961 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,01215087 0,02576992 ! actomyosin structure organization GO:0031032 12 12 0,000 0,01215087 0,0257403 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,01215087 0,02571075 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,01215087 0,02568126 ! retinoid metabolic process GO:0001523 12 12 0,000 0,01215087 0,02565184 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,01215087 0,02562249 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,01215087 0,02559321 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,01215087 0,025564 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,01215087 0,02553485 ! acute-phase response GO:0006953 12 12 0,000 0,01215087 0,02550576 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,01215087 0,02547675 ! vacuolar transport GO:0007034 12 12 0,000 0,01215087 0,0254478 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,01215087 0,02541891 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,01215087 0,02539009 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,01215087 0,02536134 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,01215087 0,02533265 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,01215087 0,02530402 ! male gonad development GO:0008584 12 12 0,000 0,01215087 0,02527546 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,01215087 0,02524697 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,01215087 0,02521854 ! renal system process GO:0003014 12 12 0,000 0,01215087 0,02519017 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,01215087 0,02516186 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,01215087 0,02513362 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,01215087 0,02510545 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,01215087 0,02507733 ! pallium development GO:0021543 13 12 0,000 0,01215087 0,02504928 ! cell fate determination GO:0001709 12 12 0,000 0,01215087 0,0250213 ! regulation of chromosome organization GO:0033044 12 12 0,000 0,01215087 0,02499337 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,01215087 0,02496551 ! somitogenesis GO:0001756 13 12 0,000 0,01215087 0,02493771 ! G1 phase GO:0051318 13 12 0,000 0,01215087 0,02490997 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,01215087 0,02488229 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,01215087 0,02485467 ! detection of light stimulus GO:0009583 13 12 0,000 0,01215087 0,02482712 ! synaptogenesis GO:0007416 12 12 0,000 0,01215087 0,02479962 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,01215087 0,02477219 ! hormone transport GO:0009914 12 12 0,000 0,01215087 0,02474482 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,01215087 0,02471751 ! heme biosynthetic process GO:0006783 12 12 0,000 0,01215087 0,02469025 ! spermatid differentiation GO:0048515 13 12 0,000 0,01215087 0,02466306 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,01215087 0,02463593 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,01215087 0,02460886 ! neural tube closure GO:0001843 13 12 0,000 0,01215087 0,02458184 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 0,000 0,01215087 0,02455489 ! negative regulation of translation GO:0017148 12 12 0,000 0,01215087 0,024528 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,01215087 0,02450116 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 0,000 0,01215087 0,02447438 ! positive regulation of DNA replication GO:0045740 14 13 0,000 0,01315771 0,02647342 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 0,000 0,01315771 0,02644456 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,01315771 0,02641575 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,01315771 0,026387 ! phenol metabolic process GO:0018958 13 13 0,000 0,01315771 0,02635832 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,01315771 0,0263297 ! gluconeogenesis GO:0006094 13 13 0,000 0,01315771 0,02630115 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,01315771 0,02627265 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,01315771 0,02624422 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,01315771 0,02621585 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,01315771 0,02618753 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,01315771 0,02615928 ! regeneration GO:0031099 13 13 0,000 0,01315771 0,0261311 ! keratinization GO:0031424 13 13 0,000 0,01315771 0,02610297 ! post-embryonic development GO:0009791 14 13 0,000 0,01315771 0,0260749 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,01315771 0,02604689 ! patterning of blood vessels GO:0001569 13 13 0,000 0,01315771 0,02601895 ! vasculogenesis GO:0001570 13 13 0,000 0,01315771 0,02599106 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,01315771 0,02596323 ! regulation of innate immune response GO:0045088 13 13 0,000 0,01315771 0,02593546 ! mitochondrial membrane organization GO:0007006 13 13 0,000 0,01315771 0,02590775 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 0,000 0,01315771 0,0258801 ! negative regulation of DNA replication GO:0008156 13 13 0,000 0,01315771 0,02585251 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,01315771 0,02582498 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,01315771 0,02579751 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,01315771 0,02577009 ! autophagy GO:0006914 13 13 0,000 0,01315771 0,02574274 ! receptor metabolic process GO:0043112 14 13 0,000 0,01315771 0,02571544 ! actin filament bundle formation GO:0051017 13 13 0,000 0,01315771 0,0256882 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,01315771 0,02566101 ! ureteric bud development GO:0001657 13 13 0,000 0,01315771 0,02563389 ! cell aging GO:0007569 13 13 0,000 0,01315771 0,02560682 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 0,000 0,01315771 0,02557981 ! regulation of endothelial cell migration GO:0010594 13 13 0,000 0,01315771 0,02555285 ! response to endoplasmic reticulum stress GO:0034976 13 13 0,000 0,01315771 0,02552595 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,01315771 0,02549911 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,01315771 0,02547233 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,01315771 0,0254456 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,01315771 0,02541893 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,01315771 0,02539231 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,01315771 0,02536575 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,01315771 0,02533924 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,01315771 0,02531279 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,01315771 0,0252864 ! vasodilation GO:0042311 14 13 0,000 0,01315771 0,02526006 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,01315771 0,02523377 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,01315771 0,02520754 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,01315771 0,02518137 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 0,01315771 0,02515525 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 0,000 0,01315771 0,02512918 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,01315771 0,02510316 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,01315771 0,0250772 ! immunoglobulin production GO:0002377 13 13 0,000 0,01315771 0,0250513 GO:0002440|production of molecular mediator of immune response, ! negative regulation of intracellular transport GO:0032387 13 13 0,000 0,01315771 0,02502545 ! negative regulation of leukocyte activation GO:0002695 13 13 0,000 0,01315771 0,02499965 ! cell-cell junction organization GO:0045216 13 13 0,000 0,01315771 0,0249739 ! regulation of cell-substrate adhesion GO:0010810 14 13 0,000 0,01315771 0,02494821 GO:0001952|regulation of cell-matrix adhesion, ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,01315771 0,02492257 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,01315771 0,02489698 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,01315771 0,02487144 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,01315771 0,02484596 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,01315771 0,02482053 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,01315771 0,02479515 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,01315771 0,02476982 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,01315771 0,02474455 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,01315771 0,02471932 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,01315771 0,02469415 ! blastocyst development GO:0001824 13 13 0,000 0,01315771 0,02466903 ! telomere organization GO:0032200 13 13 0,000 0,01315771 0,02464396 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,01315771 0,02461894 ! regulation of amine transport GO:0051952 13 13 0,000 0,01315771 0,02459397 ! tissue homeostasis GO:0001894 13 13 0,000 0,01315771 0,02456905 GO:0048871|multicellular organismal homeostasis, ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,01315771 0,02454419 ! protein tetramerization GO:0051262 13 13 0,000 0,01315771 0,02451937 ! neuron fate commitment GO:0048663 14 14 0,000 0,01416366 0,02636731 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,01416366 0,0263407 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,01416366 0,02631415 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,01416366 0,02628765 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,01416366 0,0262612 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,01416366 0,02623481 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,01416366 0,02620847 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,01416366 0,02618218 ! protein amino acid acylation GO:0043543 14 14 0,000 0,01416366 0,02615594 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,01416366 0,02612976 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,01416366 0,02610363 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,01416366 0,02607756 ! vesicle docking GO:0048278 14 14 0,000 0,01416366 0,02605153 ! superoxide metabolic process GO:0006801 15 14 0,000 0,01416366 0,02602556 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,01416366 0,02599963 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,01416366 0,02597376 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,01416366 0,02594795 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,01416366 0,02592218 ! hair cycle GO:0042633 14 14 0,000 0,01416366 0,02589646 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,01416366 0,0258708 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 0,000 0,01416366 0,02584518 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,01416366 0,02581962 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,01416366 0,0257941 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,01416366 0,02576864 ! lysosome organization GO:0007040 14 14 0,000 0,01416366 0,02574323 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,01416366 0,02571786 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,01416366 0,02569255 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,01416366 0,02566729 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,01416366 0,02564208 ! primary neural tube formation GO:0014020 15 14 0,000 0,01416366 0,02561691 ! peptide cross-linking GO:0018149 14 14 0,000 0,01416366 0,0255918 ! regulation of behavior GO:0050795 14 14 0,000 0,01416366 0,02556673 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,01416366 0,02554172 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,01416366 0,02551675 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,01416366 0,02549183 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,01416366 0,02546696 ! formation of primary germ layer GO:0001704 14 14 0,000 0,01416366 0,02544214 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,01416366 0,02541736 ! collagen fibril organization GO:0030199 14 14 0,000 0,01416366 0,02539264 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,01416366 0,02536796 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,01416366 0,02534333 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,01416366 0,02531875 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,01416366 0,02529422 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,01416366 0,02526973 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,01416366 0,02524529 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,01416366 0,0252209 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,01416366 0,02519656 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,01416366 0,02517226 ! protein import into nucleus, translocation GO:0000060 15 15 0,000 0,01516874 0,02693255 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,01516874 0,02690663 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,01516874 0,02688076 ! positive regulation of ossification GO:0045778 15 15 0,000 0,01516874 0,02685494 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,01516874 0,02682916 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,01516874 0,02680344 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,01516874 0,02677777 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,01516874 0,02675214 ! response to vitamin GO:0033273 15 15 0,000 0,01516874 0,02672657 ! regulation of transcription factor import into nucleus GO:0042990 15 15 0,000 0,01516874 0,02670104 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,01516874 0,02667556 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,01516874 0,02665013 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,01516874 0,02662475 ! ovarian follicle development GO:0001541 15 15 0,000 0,01516874 0,02659942 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,01516874 0,02657413 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,01516874 0,0265489 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,01516874 0,02652371 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,01516874 0,02649857 ! ER-nuclear signaling pathway GO:0006984 15 15 0,000 0,01516874 0,02647347 ! heme metabolic process GO:0042168 15 15 0,000 0,01516874 0,02644843 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,01516874 0,02642343 ! chromosome condensation GO:0030261 15 15 0,000 0,01516874 0,02639848 ! response to starvation GO:0042594 15 15 0,000 0,01516874 0,02637357 ! response to ionizing radiation GO:0010212 16 15 0,000 0,01516874 0,02634872 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,01516874 0,02632391 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,01516874 0,02629914 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,01516874 0,02627443 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,01516874 0,02624975 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,01516874 0,02622513 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,01516874 0,02620055 ! phospholipid transport GO:0015914 15 15 0,000 0,01516874 0,02617602 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,01516874 0,02615153 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,01516874 0,02612709 ! glutathione metabolic process GO:0006749 16 15 0,000 0,01516874 0,0261027 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,01516874 0,02607835 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,01516874 0,02605404 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,01516874 0,02602978 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,01516874 0,02600557 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,01516874 0,0259814 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,01516874 0,02595728 ! negative regulation of cell activation GO:0050866 15 15 0,000 0,01516874 0,0259332 ! protein homooligomerization GO:0051260 15 15 0,000 0,01516874 0,02590916 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,01516874 0,02588517 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,01617294 0,02757329 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,01617294 0,02754781 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,01617294 0,02752237 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,01617294 0,02749698 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,01617294 0,02747164 ! learning GO:0007612 16 16 0,000 0,01617294 0,02744634 ! circadian rhythm GO:0007623 16 16 0,000 0,01617294 0,02742109 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,01617294 0,02739589 ! positive regulation of mitosis GO:0045840 16 16 0,000 0,01617294 0,02737073 GO:0051785|positive regulation of nuclear division, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 0,000 0,01617294 0,02734562 ! vacuole organization GO:0007033 16 16 0,000 0,01617294 0,02732055 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,01617294 0,02729554 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,01617294 0,02727056 ! vesicle targeting GO:0006903 17 16 0,000 0,01617294 0,02724564 ! segmentation GO:0035282 17 16 0,000 0,01617294 0,02722075 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,01617294 0,02719592 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,01617294 0,02717113 ! iron ion homeostasis GO:0055072 16 16 0,000 0,01617294 0,02714638 ! positive regulation of cell development GO:0010720 16 16 0,000 0,01617294 0,02712168 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,01617294 0,02709702 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,01617294 0,02707241 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,01617294 0,02704785 ! cell fate specification GO:0001708 16 16 0,000 0,01617294 0,02702332 ! pentose metabolic process GO:0019321 16 16 0,000 0,01617294 0,02699885 ! fatty acid transport GO:0015908 16 16 0,000 0,01617294 0,02697441 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,01617294 0,02695002 ! cellular response to nutrient levels GO:0031669 16 16 0,000 0,01617294 0,02692568 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,01617294 0,02690138 ! cofactor catabolic process GO:0051187 16 16 0,000 0,01617294 0,02687712 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,01617294 0,02685291 ! polyol metabolic process GO:0019751 16 16 0,000 0,01617294 0,02682874 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,01617294 0,02680461 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,01617294 0,02678053 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,01617294 0,02675649 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,01617294 0,02673249 GO:0001841|neural tube formation, ! positive regulation of catabolic process GO:0009896 16 16 0,000 0,01617294 0,02670854 ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,01617294 0,02668462 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,01617294 0,02666076 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,01617294 0,02663693 ! regulation of coagulation GO:0050818 17 16 0,000 0,01617294 0,02661315 ! regulation of fibroblast proliferation GO:0048145 17 17 0,000 0,01717626 0,02823893 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,01717626 0,02821377 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 0,000 0,01717626 0,02818864 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,01717626 0,02816356 ! positive regulation of cell adhesion GO:0045785 17 17 0,000 0,01717626 0,02813853 ! myelination GO:0042552 17 17 0,000 0,01717626 0,02811354 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,01717626 0,02808859 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,01717626 0,02806369 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,01717626 0,02803883 ! leukocyte adhesion GO:0007159 17 17 0,000 0,01717626 0,02801402 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,01717626 0,02798925 ! sensory perception of smell GO:0007608 17 17 0,000 0,01717626 0,02796453 ! glucose transport GO:0015758 17 17 0,000 0,01717626 0,02793985 ! cell junction assembly GO:0034329 18 17 0,000 0,01717626 0,02791521 ! tissue remodeling GO:0048771 17 17 0,000 0,01717626 0,02789061 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,01717626 0,02786606 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,01717626 0,02784155 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,01717626 0,02781709 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,01717626 0,02779266 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,01717626 0,02776828 ! neural crest cell development GO:0014032 19 17 0,000 0,01717626 0,02774395 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 0,01717626 0,02771965 ! negative regulation of cell development GO:0010721 18 17 0,000 0,01717626 0,0276954 GO:0050768|negative regulation of neurogenesis, ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,01717626 0,02767119 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,01717626 0,02764703 ! regulation of oxidoreductase activity GO:0051341 17 17 0,000 0,01717626 0,0276229 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,01717626 0,02759882 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,01717626 0,02757478 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,01717626 0,02755078 ! pigmentation GO:0043473 17 17 0,000 0,01717626 0,02752682 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,01717626 0,02750291 ! adult locomotory behavior GO:0008344 17 17 0,000 0,01717626 0,02747903 ! embryonic organ development GO:0048568 17 17 0,000 0,01717626 0,0274552 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,01717626 0,02743141 ! liver development GO:0001889 17 17 0,000 0,01717626 0,02740766 ! gene silencing GO:0016458 17 17 0,000 0,01717626 0,02738395 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,0181787 0,02895708 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,0181787 0,02893208 ! regulation of cellular catabolic process GO:0031329 18 18 0,000 0,0181787 0,02890712 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,0181787 0,0288822 ! meiosis I GO:0007127 18 18 0,000 0,0181787 0,02885732 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,0181787 0,02883248 ! membrane docking GO:0022406 18 18 0,000 0,0181787 0,02880769 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,0181787 0,02878294 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,0181787 0,02875824 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,0181787 0,02873357 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,0181787 0,02870895 ! hexose transport GO:0008645 18 18 0,000 0,0181787 0,02868437 GO:0015749|monosaccharide transport, ! cholesterol homeostasis GO:0042632 18 18 0,000 0,0181787 0,02865983 GO:0055092|sterol homeostasis, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 0,000 0,0181787 0,02863534 ! striated muscle contraction GO:0006941 18 18 0,000 0,0181787 0,02861089 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,0181787 0,02858647 GO:0006639|acylglycerol metabolic process, ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,0181787 0,0285621 ! ceramide metabolic process GO:0006672 18 18 0,000 0,0181787 0,02853777 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,0181787 0,02851349 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,0181787 0,02848924 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,0181787 0,02846504 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,0181787 0,02844087 ! B cell differentiation GO:0030183 18 18 0,000 0,0181787 0,02841675 ! cellular response to extracellular stimulus GO:0031668 18 18 0,000 0,0181787 0,02839267 ! ensheathment of neurons GO:0007272 18 18 0,000 0,0181787 0,02836863 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 18 18 0,000 0,0181787 0,02834463 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,0181787 0,02832067 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,0181787 0,02829675 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 0,000 0,0181787 0,02827287 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,0181787 0,02824903 ! DNA damage checkpoint GO:0000077 19 19 0,000 0,01918027 0,02978032 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,01918027 0,02975525 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,01918027 0,02973022 GO:0006956|complement activation, ! negative regulation of DNA metabolic process GO:0051053 19 19 0,000 0,01918027 0,02970524 ! glial cell differentiation GO:0010001 19 19 0,000 0,01918027 0,0296803 ! regulation of pH GO:0006885 19 19 0,000 0,01918027 0,0296554 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,01918027 0,02963054 ! feeding behavior GO:0007631 19 19 0,000 0,01918027 0,02960572 ! regulation of endothelial cell proliferation GO:0001936 19 19 0,000 0,01918027 0,02958095 ! peroxisome organization GO:0007031 19 19 0,000 0,01918027 0,02955622 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,01918027 0,02953152 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,01918027 0,02950687 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,01918027 0,02948226 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 0,000 0,01918027 0,02945769 ! metanephros development GO:0001656 19 19 0,000 0,01918027 0,02943317 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,01918027 0,02940868 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,01918027 0,02938423 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,01918027 0,02935983 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,01918027 0,02933546 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,01918027 0,02931114 ! peripheral nervous system development GO:0007422 19 19 0,000 0,01918027 0,02928685 ! regulation of protein stability GO:0031647 19 19 0,000 0,01918027 0,02926261 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,01918027 0,02923841 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,01918027 0,02921424 ! dorsal/ventral pattern formation GO:0009953 19 19 0,000 0,01918027 0,02919012 ! eye morphogenesis GO:0048592 19 19 0,000 0,01918027 0,02916603 ! regulation of cell shape GO:0008360 21 19 0,000 0,01918027 0,02914199 ! placenta development GO:0001890 19 19 0,000 0,01918027 0,02911799 ! response to heat GO:0009408 19 19 0,000 0,01918027 0,02909402 ! vesicle localization GO:0051648 20 19 0,000 0,01918027 0,02907009 ! regulation of muscle development GO:0048634 21 20 0,000 0,02018096 0,03056163 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,02018096 0,03053654 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,02018096 0,03051149 ! negative regulation of binding GO:0051100 21 20 0,000 0,02018096 0,03048648 ! organic ether metabolic process GO:0018904 20 20 0,000 0,02018096 0,03046151 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,02018096 0,03043658 ! neural tube development GO:0021915 21 20 0,000 0,02018096 0,0304117 ! nucleus organization GO:0006997 20 20 0,000 0,02018096 0,03038685 ! phagocytosis GO:0006909 21 20 0,000 0,02018096 0,03036205 ! positive regulation of gene-specific transcription GO:0043193 20 20 0,000 0,02018096 0,03033728 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,02018096 0,03031256 ! protein targeting to membrane GO:0006612 22 20 0,000 0,02018096 0,03028787 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,02018096 0,03026323 ! chromatin remodeling GO:0006338 20 20 0,000 0,02018096 0,03023862 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,02018096 0,03021406 ! peptidyl-tyrosine modification GO:0018212 21 20 0,000 0,02018096 0,03018953 ! lipid oxidation GO:0034440 20 20 0,000 0,02018096 0,03016505 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,02018096 0,03014061 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,02018096 0,0301162 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,02018096 0,03009183 ! RNA modification GO:0009451 20 20 0,000 0,02018096 0,03006751 ! regulation of B cell activation GO:0050864 20 20 0,000 0,02018096 0,03004322 ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,02118077 0,03150619 ! mRNA catabolic process GO:0006402 21 21 0,000 0,02118077 0,03148078 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 0,000 0,02118077 0,03145541 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,02118077 0,03143009 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! mammary gland development GO:0030879 23 21 0,000 0,02118077 0,0314048 ! protein amino acid lipidation GO:0006497 21 21 0,000 0,02118077 0,03137955 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,02118077 0,03135435 ! Notch signaling pathway GO:0007219 22 21 0,000 0,02118077 0,03132919 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,02118077 0,03130406 ! ear morphogenesis GO:0042471 21 21 0,000 0,02118077 0,03127898 ! organic anion transport GO:0015711 21 21 0,000 0,02118077 0,03125394 ! cholesterol transport GO:0030301 21 21 0,000 0,02118077 0,03122893 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,02118077 0,03120397 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,02118077 0,03117905 GO:0032313|regulation of Rab GTPase activity, ! DNA integrity checkpoint GO:0031570 21 21 0,000 0,02118077 0,03115416 ! regulation of protein import into nucleus GO:0042306 21 21 0,000 0,02118077 0,03112932 ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,02118077 0,03110452 ! regulation of action potential in neuron GO:0019228 21 21 0,000 0,02118077 0,03107975 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,02118077 0,03105502 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,02118077 0,03103034 ! regulation of proteolysis GO:0030162 21 21 0,000 0,02118077 0,03100569 ! negative regulation of hydrolase activity GO:0051346 21 21 0,000 0,02118077 0,03098108 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,02118077 0,03095652 ! negative regulation of protein transport GO:0051224 21 21 0,000 0,02118077 0,03093199 ! positive regulation of transcription factor activity GO:0051091 22 22 0,000 0,02217971 0,03236517 GO:0090047|positive regulation of transcription regulator activity, ! RNA export from nucleus GO:0006405 22 22 0,000 0,02217971 0,03233957 ! positive regulation of DNA metabolic process GO:0051054 23 22 0,000 0,02217971 0,032314 ! sister chromatid segregation GO:0000819 22 22 0,000 0,02217971 0,03228848 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,02217971 0,03226299 ! regulation of ion transport GO:0043269 22 22 0,000 0,02217971 0,03223755 ! odontogenesis GO:0042476 22 22 0,000 0,02217971 0,03221215 ! cell junction organization GO:0034330 23 22 0,000 0,02217971 0,03218678 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,02217971 0,03216146 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,02217971 0,03213617 ! embryonic skeletal system development GO:0048706 22 22 0,000 0,02217971 0,03211093 ! maintenance of protein location in cell GO:0032507 23 22 0,000 0,02217971 0,03208573 ! ovulation cycle process GO:0022602 22 22 0,000 0,02217971 0,03206056 ! spindle organization GO:0007051 22 22 0,000 0,02217971 0,03203543 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,02217971 0,03201035 ! cell chemotaxis GO:0060326 23 22 0,000 0,02217971 0,0319853 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,02217971 0,03196029 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,02217971 0,03193532 ! male sex differentiation GO:0046661 22 22 0,000 0,02217971 0,03191039 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,02217971 0,0318855 ! biopolymer methylation GO:0043414 22 22 0,000 0,02217971 0,03186065 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,02217971 0,03183584 ! detection of external stimulus GO:0009581 23 22 0,000 0,02217971 0,03181106 ! neuron migration GO:0001764 22 22 0,000 0,02217971 0,03178633 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,02217971 0,03176163 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,02217971 0,03173697 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,02217971 0,03171235 ! aerobic respiration GO:0009060 22 22 0,000 0,02217971 0,03168776 ! cytokine production GO:0001816 22 22 0,000 0,02217971 0,03166322 ! cytokinesis GO:0000910 23 22 0,000 0,02217971 0,03163871 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,02217971 0,03161424 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,02317778 0,03301132 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,02317778 0,03298583 ! viral infectious cycle GO:0019058 23 23 0,000 0,02317778 0,03296038 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,02317778 0,03293497 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,02317778 0,03290959 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,02317778 0,03288426 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,02317778 0,03285896 ! mitotic cell cycle checkpoint GO:0007093 24 23 0,000 0,02317778 0,03283371 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,02317778 0,03280849 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,02317778 0,03278331 ! endocrine system development GO:0035270 23 23 0,000 0,02317778 0,03275817 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,02317778 0,03273307 ! positive regulation of growth GO:0045927 23 23 0,000 0,02317778 0,032708 ! female gonad development GO:0008585 23 23 0,000 0,02317778 0,03268298 ! monovalent inorganic cation homeostasis GO:0055067 23 23 0,000 0,02317778 0,03265799 ! lipid homeostasis GO:0055088 23 23 0,000 0,02317778 0,03263304 ! calcium-mediated signaling GO:0019722 23 23 0,000 0,02317778 0,03260813 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,02317778 0,03258326 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,02317778 0,03255842 ! cell projection assembly GO:0030031 25 23 0,000 0,02317778 0,03253363 ! mitochondrial transport GO:0006839 24 24 0,000 0,02417497 0,03390752 ! regulation of action potential GO:0001508 24 24 0,000 0,02417497 0,03388173 ! gliogenesis GO:0042063 24 24 0,000 0,02417497 0,03385599 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,02417497 0,03383028 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,02417497 0,03380461 ! glucose homeostasis GO:0042593 24 24 0,000 0,02417497 0,03377898 GO:0033500|carbohydrate homeostasis, ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,02417497 0,03375339 ! T cell differentiation GO:0030217 24 24 0,000 0,02417497 0,03372784 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,02417497 0,03370233 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,02417497 0,03367685 ! ovulation cycle GO:0042698 24 24 0,000 0,02417497 0,03365142 ! maintenance of protein location GO:0045185 25 24 0,000 0,02417497 0,03362602 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,02417497 0,03360066 ! androgen receptor signaling pathway GO:0030521 24 24 0,000 0,02417497 0,03357534 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,02417497 0,03355006 ! glucan metabolic process GO:0044042 25 24 0,000 0,02417497 0,03352481 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,0251713 0,03488022 ! negative regulation of secretion GO:0051048 26 25 0,000 0,0251713 0,03485402 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,0251713 0,03482785 ! regulation of gene-specific transcription GO:0032583 25 25 0,000 0,0251713 0,03480172 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,0251713 0,03477564 ! cellular component disassembly GO:0022411 26 25 0,000 0,0251713 0,03474959 ! endosome transport GO:0016197 25 25 0,000 0,0251713 0,03472358 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,0251713 0,03469761 ! regulation of intracellular protein transport GO:0033157 25 25 0,000 0,0251713 0,03467167 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,0251713 0,03464578 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,0251713 0,03461992 ! regulation of T cell proliferation GO:0042129 25 25 0,000 0,0251713 0,03459411 ! excretion GO:0007588 25 25 0,000 0,0251713 0,03456833 ! positive regulation of DNA binding GO:0043388 26 25 0,000 0,0251713 0,03454259 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,0251713 0,03451689 ! gastrulation GO:0007369 25 25 0,000 0,0251713 0,03449123 ! heart morphogenesis GO:0003007 25 25 0,000 0,0251713 0,0344656 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,0251713 0,03444001 ! regulation of endocytosis GO:0030100 25 25 0,000 0,0251713 0,03441446 ! negative regulation of immune system process GO:0002683 25 25 0,000 0,0251713 0,03438895 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,0251713 0,03436348 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,0251713 0,03433804 ! positive regulation of binding GO:0051099 27 26 0,000 0,02616674 0,03566961 ! positive regulation of defense response GO:0031349 26 26 0,000 0,02616674 0,03564324 ! glycolysis GO:0006096 26 26 0,000 0,02616674 0,03561692 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,02616674 0,03559063 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,02616674 0,03556439 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,02616674 0,03553818 ! negative regulation of cell migration GO:0030336 26 26 0,000 0,02616674 0,03551201 ! induction of apoptosis by intracellular signals GO:0008629 26 26 0,000 0,02616674 0,03548588 ! cellular defense response GO:0006968 26 26 0,000 0,02616674 0,03545979 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,02616674 0,03543373 ! regulation of T cell differentiation GO:0045580 26 26 0,000 0,02616674 0,03540772 ! regulation of protein secretion GO:0050708 26 26 0,000 0,02616674 0,03538174 ! germ cell development GO:0007281 27 26 0,000 0,02616674 0,0353558 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,02616674 0,0353299 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,02616674 0,03530403 ! maintenance of location in cell GO:0051651 27 26 0,000 0,02616674 0,03527821 ! synapse organization GO:0050808 26 26 0,000 0,02616674 0,03525242 ! chloride transport GO:0006821 27 27 0,000 0,02716132 0,03656561 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 0,000 0,02716132 0,03653892 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,02716132 0,03651227 ! energy reserve metabolic process GO:0006112 28 27 0,000 0,02716132 0,03648565 ! learning or memory GO:0007611 28 27 0,000 0,02716132 0,03645908 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,02716132 0,03643254 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,02716132 0,03640605 ! peptide metabolic process GO:0006518 29 27 0,000 0,02716132 0,03637959 ! activation of caspase activity GO:0006919 27 27 0,000 0,02716132 0,03635317 ! mesenchymal cell development GO:0014031 29 27 0,000 0,02716132 0,03632679 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! inner ear development GO:0048839 27 27 0,000 0,02716132 0,03630045 ! defense response to bacterium GO:0042742 27 27 0,000 0,02716132 0,03627414 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,02716132 0,03624788 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,02716132 0,03622165 ! cell growth GO:0016049 27 27 0,000 0,02716132 0,03619546 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,02815503 0,03749257 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,02815503 0,0374655 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,02815503 0,03743847 ! carbohydrate transport GO:0008643 28 28 0,000 0,02815503 0,03741148 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,02815503 0,03738452 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,02815503 0,03735761 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,02815503 0,03733073 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,02815503 0,03730389 ! histone modification GO:0016570 28 28 0,000 0,02815503 0,0372771 ! protein amino acid autophosphorylation GO:0046777 28 28 0,000 0,02815503 0,03725034 ! developmental growth GO:0048589 28 28 0,000 0,02815503 0,03722361 ! regulation of mast cell proliferation GO:0070666 28 28 0,000 0,02815503 0,03719693 ! cartilage development GO:0051216 29 28 0,000 0,02815503 0,03717028 ! positive regulation of cell cycle GO:0045787 29 29 0,000 0,02914786 0,03845348 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,02914786 0,03842598 ! viral reproductive process GO:0022415 29 29 0,000 0,02914786 0,03839851 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,02914786 0,03837108 ! leukocyte migration GO:0050900 30 29 0,000 0,02914786 0,03834369 ! branching morphogenesis of a tube GO:0048754 29 29 0,000 0,02914786 0,03831634 ! regulation of epithelial cell proliferation GO:0050678 29 29 0,000 0,02914786 0,03828903 ! regulation of lymphocyte proliferation GO:0050670 29 29 0,000 0,02914786 0,03826176 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! antigen processing and presentation GO:0019882 29 29 0,000 0,02914786 0,03823453 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,02914786 0,03820734 ! tRNA processing GO:0008033 29 29 0,000 0,02914786 0,03818018 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,02914786 0,03815306 ! covalent chromatin modification GO:0016569 29 29 0,000 0,02914786 0,03812599 ! adult behavior GO:0030534 30 29 0,000 0,02914786 0,03809895 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,02914786 0,03807195 ! positive regulation of protein transport GO:0051222 29 29 0,000 0,02914786 0,03804498 ! transition metal ion transport GO:0000041 31 30 0,000 0,03013983 0,0393119 ! RNA catabolic process GO:0006401 30 30 0,000 0,03013983 0,03928409 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,03013983 0,03925633 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,03013983 0,03922861 ! positive regulation of peptidase activity GO:0010952 30 30 0,000 0,03013983 0,03920092 GO:0043280|positive regulation of caspase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,03013983 0,03917328 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,03013983 0,03914567 ! activation of phospholipase C activity GO:0007202 30 30 0,000 0,03013983 0,03911811 GO:0010863|positive regulation of phospholipase C activity, ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,03013983 0,03909058 ! positive regulation of response to external stimulus GO:0032103 30 30 0,000 0,03013983 0,03906309 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,03013983 0,03903564 ! skeletal system morphogenesis GO:0048705 31 30 0,000 0,03013983 0,03900822 ! response to temperature stimulus GO:0009266 30 30 0,000 0,03013983 0,03898085 ! regulation of ossification GO:0030278 30 30 0,000 0,03013983 0,03895351 ! vascular process in circulatory system GO:0003018 31 30 0,000 0,03013983 0,03892622 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,03013983 0,03889896 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,03013983 0,03887174 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,03013983 0,03884455 ! vesicle organization GO:0016050 30 30 0,000 0,03013983 0,03881741 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,03013983 0,0387903 ! establishment of organelle localization GO:0051656 31 30 0,000 0,03013983 0,03876323 ! regulation of translational initiation GO:0006446 31 31 0,000 0,03113093 0,04000997 ! skeletal muscle fiber development GO:0048741 31 31 0,000 0,03113093 0,03998209 ! membrane fusion GO:0006944 31 31 0,000 0,03113093 0,03995425 ! B cell activation GO:0042113 31 31 0,000 0,03113093 0,03992645 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,03113093 0,03989868 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,03113093 0,03987095 ! positive regulation of phospholipase activity GO:0010518 31 31 0,000 0,03113093 0,03984327 ! ion transmembrane transport GO:0034220 31 31 0,000 0,03113093 0,03981562 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! aging GO:0007568 32 31 0,000 0,03113093 0,039788 ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,03113093 0,03976043 ! digestion GO:0007586 31 31 0,000 0,03113093 0,0397329 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,03113093 0,0397054 ! regulation of heart contraction GO:0008016 31 31 0,000 0,03113093 0,03967794 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,03113093 0,03965052 ! camera-type eye development GO:0043010 31 31 0,000 0,03113093 0,03962314 ! extracellular matrix organization GO:0030198 31 31 0,000 0,03113093 0,03959579 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,03113093 0,03956848 ! regulation of intracellular transport GO:0032386 31 31 0,000 0,03113093 0,03954121 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,03113093 0,03951398 ! regulation of myeloid cell differentiation GO:0045637 32 31 0,000 0,03113093 0,03948679 ! negative regulation of cell motion GO:0051271 31 31 0,000 0,03113093 0,03945963 ! negative regulation of cell growth GO:0030308 32 32 0,000 0,03212116 0,0406868 ! cell redox homeostasis GO:0045454 32 32 0,000 0,03212116 0,04065886 ! muscle fiber development GO:0048747 32 32 0,000 0,03212116 0,04063095 ! glucose catabolic process GO:0006007 32 32 0,000 0,03212116 0,04060308 ! lipid modification GO:0030258 32 32 0,000 0,03212116 0,04057525 ! regulation of phospholipase activity GO:0010517 32 32 0,000 0,03212116 0,04054746 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,03212116 0,04051971 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,03212116 0,04049199 ! cell maturation GO:0048469 32 32 0,000 0,03212116 0,04046432 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 0,000 0,03212116 0,04043668 ! morphogenesis of a branching structure GO:0001763 32 32 0,000 0,03212116 0,04040908 ! nuclear export GO:0051168 32 32 0,000 0,03212116 0,04038151 ! regulation of lymphocyte differentiation GO:0045619 32 32 0,000 0,03212116 0,04035399 ! kidney development GO:0001822 32 32 0,000 0,03212116 0,0403265 ! positive regulation of lipase activity GO:0060193 32 32 0,000 0,03212116 0,04029904 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,03212116 0,04027163 ! maintenance of location GO:0051235 33 32 0,000 0,03212116 0,04024425 ! negative regulation of cell size GO:0045792 33 33 0,000 0,03311052 0,04145563 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,03311052 0,04142749 ! amino acid transport GO:0006865 33 33 0,000 0,03311052 0,04139938 ! activation of protein kinase activity GO:0032147 35 33 0,000 0,03311052 0,04137132 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,03311052 0,04134329 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,03311052 0,0413153 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,03311052 0,04128734 ! regulation of neuron differentiation GO:0045664 34 33 0,000 0,03311052 0,04125943 ! regulation of neuron apoptosis GO:0043523 34 33 0,000 0,03311052 0,04123155 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,03311052 0,04120371 ! regulation of actin filament length GO:0030832 34 34 0,000 0,03409902 0,04240519 ! regulation of angiogenesis GO:0045765 35 34 0,000 0,03409902 0,04237659 ! regulation of bone remodeling GO:0046850 34 34 0,000 0,03409902 0,04234804 ! response to metal ion GO:0010038 34 34 0,000 0,03409902 0,04231952 ! ear development GO:0043583 34 34 0,000 0,03409902 0,04229104 ! muscle cell differentiation GO:0042692 35 34 0,000 0,03409902 0,0422626 ! cellular polysaccharide metabolic process GO:0044264 35 34 0,000 0,03409902 0,0422342 ! regulation of protein catabolic process GO:0042176 35 34 0,000 0,03409902 0,04220583 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,03409902 0,04217751 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,03409902 0,04214922 ! regulation of lipid metabolic process GO:0019216 34 34 0,000 0,03409902 0,04212097 ! secondary metabolic process GO:0019748 34 34 0,000 0,03409902 0,04209276 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,03409902 0,04206458 ! viral reproduction GO:0016032 34 34 0,000 0,03409902 0,04203645 ! detection of stimulus GO:0051606 36 34 0,000 0,03409902 0,04200835 ! acute inflammatory response GO:0002526 35 35 0,000 0,03508665 0,04319618 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 0,000 0,03508665 0,04316735 ! regulation of cellular component size GO:0032535 35 35 0,000 0,03508665 0,04313855 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,03508665 0,04310979 ! mesoderm development GO:0007498 35 35 0,000 0,03508665 0,04308107 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,03508665 0,04305239 GO:0048609|reproductive process in a multicellular organism, ! regulation of cell morphogenesis GO:0022604 38 35 0,000 0,03508665 0,04302374 ! positive regulation of phosphorylation GO:0042327 35 35 0,000 0,03508665 0,04299514 ! regulation of tissue remodeling GO:0034103 35 35 0,000 0,03508665 0,04296657 ! inorganic anion transport GO:0015698 35 35 0,000 0,03508665 0,04293804 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,03508665 0,04290955 ! regulation of immune effector process GO:0002697 35 35 0,000 0,03508665 0,04288109 ! hydrogen transport GO:0006818 36 36 0,000 0,03607341 0,04405785 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,03607341 0,04402867 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,03607341 0,04399953 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,03607341 0,04397043 ! regulation of mitosis GO:0007088 37 36 0,000 0,03607341 0,04394137 GO:0051783|regulation of nuclear division, ! positive regulation of cell migration GO:0030335 36 36 0,000 0,03607341 0,04391235 ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,03607341 0,04388336 GO:0035113|embryonic appendage morphogenesis, ! positive regulation of phosphorus metabolic process GO:0010562 36 36 0,000 0,03607341 0,04385441 GO:0045937|positive regulation of phosphate metabolic process, ! female pregnancy GO:0007565 37 36 0,000 0,03607341 0,04382551 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,03607341 0,04379663 ! positive regulation of organelle organization GO:0010638 36 36 0,000 0,03607341 0,0437678 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,03607341 0,04373901 ! integrin-mediated signaling pathway GO:0007229 36 36 0,000 0,03607341 0,04371025 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,03607341 0,04368153 ! gonad development GO:0008406 36 36 0,000 0,03607341 0,04365285 ! regulation of lipase activity GO:0060191 36 36 0,000 0,03607341 0,04362421 ! activation of immune response GO:0002253 36 36 0,000 0,03607341 0,0435956 ! coagulation GO:0050817 39 36 0,000 0,03607341 0,04356703 GO:0007596|blood coagulation, ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,03705931 0,04472842 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! regulation of transcription factor activity GO:0051090 38 37 0,000 0,03705931 0,04469915 GO:0090046|regulation of transcription regulator activity, ! meiosis GO:0007126 37 37 0,000 0,03705931 0,04466992 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of protein kinase activity GO:0006469 37 37 0,000 0,03705931 0,04464072 ! response to drug GO:0042493 37 37 0,000 0,03705931 0,04461156 ! lung development GO:0030324 38 37 0,000 0,03705931 0,04458244 ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,03705931 0,04455336 ! eye development GO:0001654 37 37 0,000 0,03705931 0,04452432 ! negative regulation of growth GO:0045926 37 37 0,000 0,03705931 0,04449531 ! DNA damage response, signal transduction GO:0042770 37 37 0,000 0,03705931 0,04446634 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,03705931 0,04443741 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,03705931 0,04440852 ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,03705931 0,04437966 ! adaptive immune response GO:0002250 37 37 0,000 0,03705931 0,04435085 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of secretion GO:0051047 39 38 0,000 0,03804434 0,04550014 ! neurotransmitter transport GO:0006836 40 38 0,000 0,03804434 0,04547063 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,03804434 0,04544117 ! exocytosis GO:0006887 40 38 0,000 0,03804434 0,04541173 ! negative regulation of kinase activity GO:0033673 38 38 0,000 0,03804434 0,04538234 ! cell-matrix adhesion GO:0007160 39 38 0,000 0,03804434 0,04535299 ! chromosome segregation GO:0007059 38 38 0,000 0,03804434 0,04532367 ! urogenital system development GO:0001655 38 38 0,000 0,03804434 0,04529439 ! hexose catabolic process GO:0019320 38 38 0,000 0,03804434 0,04526515 ! RNA elongation GO:0006354 38 38 0,000 0,03804434 0,04523595 ! meiotic cell cycle GO:0051321 38 38 0,000 0,03804434 0,04520678 ! axon guidance GO:0007411 39 38 0,000 0,03804434 0,04517765 ! regulation of neurological system process GO:0031644 38 38 0,000 0,03804434 0,04514856 ! steroid hormone receptor signaling pathway GO:0030518 38 38 0,000 0,03804434 0,04511951 ! regulation of homeostatic process GO:0032844 38 38 0,000 0,03804434 0,04509049 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,03902851 0,04622721 ! hemostasis GO:0007599 42 39 0,000 0,03902851 0,04619752 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,03902851 0,04616787 ! activation of MAPK activity GO:0000187 39 39 0,000 0,03902851 0,04613826 ! respiratory tube development GO:0030323 40 39 0,000 0,03902851 0,04610868 ! response to unfolded protein GO:0006986 39 39 0,000 0,03902851 0,04607914 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,03902851 0,04604964 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,03902851 0,04602018 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,03902851 0,04599076 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,03902851 0,04596137 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,03902851 0,04593202 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,03902851 0,04590271 ! respiratory system development GO:0060541 40 39 0,000 0,03902851 0,04587343 ! developmental maturation GO:0021700 39 39 0,000 0,03902851 0,0458442 ! lymphocyte differentiation GO:0030098 39 39 0,000 0,03902851 0,045815 ! limb development GO:0060173 39 39 0,000 0,03902851 0,04578583 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! protein oligomerization GO:0051259 39 39 0,000 0,03902851 0,04575671 ! positive regulation of cell motion GO:0051272 39 39 0,000 0,03902851 0,04572762 ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,04001182 0,04684992 ! DNA catabolic process GO:0006308 41 40 0,000 0,04001182 0,04682018 ! negative regulation of transferase activity GO:0051348 40 40 0,000 0,04001182 0,04679047 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 0,000 0,04001182 0,0467608 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,04001182 0,04673116 ! organelle localization GO:0051640 41 40 0,000 0,04001182 0,04670157 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,04099426 0,04781799 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! cell cycle checkpoint GO:0000075 42 41 0,000 0,04099426 0,04778774 ! amine catabolic process GO:0009310 42 41 0,000 0,04099426 0,04775754 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,04099426 0,04772737 ! regulation of caspase activity GO:0043281 41 41 0,000 0,04099426 0,04769724 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,04099426 0,04766714 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,04099426 0,04763709 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,04099426 0,04760707 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,04099426 0,04757709 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,04197584 0,04868564 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,04197584 0,04865502 ! regulation of endopeptidase activity GO:0052548 42 42 0,000 0,04197584 0,04862444 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,04197584 0,04859389 ! cell-substrate adhesion GO:0031589 43 42 0,000 0,04197584 0,04856339 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,04197584 0,04853292 ! protein ubiquitination GO:0016567 43 42 0,000 0,04197584 0,04850249 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,04197584 0,0484721 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! response to protein stimulus GO:0051789 42 42 0,000 0,04197584 0,04844175 ! forebrain development GO:0030900 43 42 0,000 0,04197584 0,04841144 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,04197584 0,04838116 ! reproductive structure development GO:0048608 43 43 0,000 0,04295656 0,04948059 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,04295656 0,04944969 ! mitochondrion organization GO:0007005 44 43 0,000 0,04295656 0,04941882 ! alcohol catabolic process GO:0046164 43 43 0,000 0,04295656 0,04938799 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,04295656 0,0493572 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,04295656 0,04932645 ! humoral immune response GO:0006959 44 44 0,000 0,04393642 0,05042019 ! mRNA transport GO:0051028 44 44 0,000 0,04393642 0,05038882 ! protein import into nucleus GO:0006606 44 44 0,000 0,04393642 0,05035748 ! negative regulation of organelle organization GO:0010639 45 44 0,000 0,04393642 0,05032618 ! vitamin metabolic process GO:0006766 44 44 0,000 0,04393642 0,05029492 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,04393642 0,0502637 ! amine biosynthetic process GO:0009309 46 45 0,000 0,04491542 0,05135182 ! homophilic cell adhesion GO:0007156 45 45 0,000 0,04491542 0,05131998 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,04491542 0,05128818 ! regulation of DNA binding GO:0051101 47 45 0,000 0,04491542 0,05125642 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,04491542 0,05122471 ! nuclear import GO:0051170 45 45 0,000 0,04491542 0,05119303 ! Wnt receptor signaling pathway GO:0016055 46 45 0,000 0,04491542 0,05116139 ! protein processing GO:0016485 45 45 0,000 0,04491542 0,05112979 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,04589356 0,05221101 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,04589356 0,0521788 ! tube morphogenesis GO:0035239 47 46 0,000 0,04589356 0,05214663 ! regulation of peptidase activity GO:0052547 46 46 0,000 0,04589356 0,0521145 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,04589356 0,05208241 ! regulation of membrane potential GO:0042391 46 46 0,000 0,04589356 0,05205036 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,04687085 0,05312606 ! regulation of blood pressure GO:0008217 48 47 0,000 0,04687085 0,05309341 ! sex differentiation GO:0007548 47 47 0,000 0,04687085 0,05306079 ! amine transport GO:0015837 47 47 0,000 0,04687085 0,05302822 ! rhythmic process GO:0048511 47 47 0,000 0,04687085 0,05299569 ! regulation of catabolic process GO:0009894 48 47 0,000 0,04687085 0,05296319 ! calcium ion transport GO:0006816 48 48 0,000 0,04784727 0,05403341 ! actin filament organization GO:0007015 50 48 0,000 0,04784727 0,05400032 ! regulation of cell cycle process GO:0010564 50 48 0,000 0,04784727 0,05396727 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,04784727 0,05393426 ! protein localization in nucleus GO:0034504 48 48 0,000 0,04784727 0,0539013 ! DNA recombination GO:0006310 48 48 0,000 0,04784727 0,05386837 ! leukocyte differentiation GO:0002521 50 49 0,000 0,04882284 0,05493314 ! ossification GO:0001503 50 49 0,000 0,04882284 0,05489963 GO:0060348|bone development, ! gland development GO:0048732 51 49 0,000 0,04882284 0,05486615 ! cell cycle arrest GO:0007050 49 49 0,000 0,04882284 0,05483272 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,04882284 0,05479932 ! divalent metal ion transport GO:0070838 49 49 0,000 0,04882284 0,05476597 ! skeletal muscle tissue development GO:0007519 50 49 0,000 0,04882284 0,05473266 GO:0060538|skeletal muscle organ development, ! response to nutrient GO:0007584 49 49 0,000 0,04882284 0,05469938 ! response to bacterium GO:0009617 50 49 0,000 0,04882284 0,05466615 ! positive regulation of MAP kinase activity GO:0043406 50 49 0,000 0,04882284 0,05463296 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,04882284 0,05459981 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,04882284 0,0545667 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,04979755 0,05562235 ! negative regulation of transport GO:0051051 51 50 0,000 0,04979755 0,05558866 ! chromatin assembly GO:0031497 50 50 0,000 0,04979755 0,05555501 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,04979755 0,0555214 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! T cell activation GO:0042110 51 50 0,000 0,04979755 0,05548783 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 0,000 0,04979755 0,05545431 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,04979755 0,05542082 ! regulation of neurogenesis GO:0050767 51 50 0,000 0,04979755 0,05538737 ! transcription initiation GO:0006352 50 50 0,000 0,04979755 0,05535397 ! anatomical structure homeostasis GO:0060249 51 50 0,000 0,04979755 0,0553206 ! anterior/posterior pattern formation GO:0009952 51 50 0,000 0,04979755 0,05528728 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,0507714 0,05633455 ! protein modification by small protein conjugation GO:0032446 52 51 0,000 0,0507714 0,05630066 ! positive regulation of immune response GO:0050778 51 51 0,000 0,0507714 0,0562668 ! rRNA metabolic process GO:0016072 51 51 0,000 0,0507714 0,05623299 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,0507714 0,05619921 ! interphase of mitotic cell cycle GO:0051329 52 51 0,000 0,0507714 0,05616548 GO:0051325|interphase, ! ATP biosynthetic process GO:0006754 51 51 0,000 0,0507714 0,05613179 ! protein maturation GO:0051604 51 51 0,000 0,0507714 0,05609813 ! RNA localization GO:0006403 52 52 0,000 0,0517444 0,05713896 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,0517444 0,05710474 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 0,000 0,0517444 0,05707057 ! cell fate commitment GO:0045165 52 52 0,000 0,0517444 0,05703644 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,0517444 0,05700235 ! regulation of body fluid levels GO:0050878 55 52 0,000 0,0517444 0,05696829 ! sodium ion transport GO:0006814 53 53 0,000 0,05271654 0,05800393 ! tRNA metabolic process GO:0006399 53 53 0,000 0,05271654 0,05796932 ! response to hypoxia GO:0001666 53 53 0,000 0,05271654 0,05793475 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,05271654 0,05790023 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,05271654 0,05786574 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,05271654 0,0578313 ! regulation of T cell activation GO:0050863 53 53 0,000 0,05271654 0,0577969 ! regulation of protein transport GO:0051223 53 53 0,000 0,05271654 0,05776253 GO:0070201|regulation of establishment of protein localization, ! protein amino acid dephosphorylation GO:0006470 55 54 0,000 0,05368783 0,05879184 ! response to oxygen levels GO:0070482 55 54 0,000 0,05368783 0,05875693 ! response to virus GO:0009615 54 54 0,000 0,05368783 0,05872206 ! hormone metabolic process GO:0042445 55 54 0,000 0,05368783 0,05868723 ! sulfur metabolic process GO:0006790 55 54 0,000 0,05368783 0,05865244 ! negative regulation of multicellular organismal process GO:0051241 55 54 0,000 0,05368783 0,05861769 ! nucleosome organization GO:0034728 55 55 0,000 0,05465826 0,0596419 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,05465826 0,05960661 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! microtubule cytoskeleton organization GO:0000226 55 55 0,000 0,05465826 0,05957136 ! in utero embryonic development GO:0001701 55 55 0,000 0,05465826 0,05953616 ! regulation of cell adhesion GO:0030155 56 55 0,000 0,05465826 0,05950099 ! protein modification by small protein conjugation or removal GO:0070647 56 55 0,000 0,05465826 0,05946587 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,05562784 0,06048502 ! reproductive developmental process GO:0003006 56 56 0,000 0,05562784 0,06044936 ! extracellular structure organization GO:0043062 56 56 0,000 0,05562784 0,06041374 ! regulation of nervous system development GO:0051960 57 56 0,000 0,05562784 0,06037816 ! regulation of binding GO:0051098 60 57 0,000 0,05659657 0,06139346 ! ATP metabolic process GO:0046034 57 57 0,000 0,05659657 0,06135734 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,05659657 0,06132127 ! regulation of protein localization GO:0032880 58 57 0,000 0,05659657 0,06128524 ! innate immune response GO:0045087 58 58 0,000 0,05756445 0,0622967 ! dephosphorylation GO:0016311 60 59 0,000 0,05853147 0,06330605 ! carboxylic acid transport GO:0046942 59 59 0,000 0,05853147 0,06326892 GO:0015849|organic acid transport, ! peptidyl-amino acid modification GO:0018193 61 59 0,000 0,05853147 0,06323183 ! regulation of cell development GO:0060284 60 59 0,000 0,05853147 0,06319479 ! sterol metabolic process GO:0016125 59 59 0,000 0,05853147 0,06315779 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,05853147 0,06312084 ! protein localization in organelle GO:0033365 59 59 0,000 0,05853147 0,06308392 ! immune effector process GO:0002252 59 59 0,000 0,05853147 0,06304705 ! potassium ion transport GO:0006813 60 60 0,000 0,05949765 0,06405033 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 0,000 0,05949765 0,06401294 ! protein polymerization GO:0051258 65 60 0,000 0,05949765 0,06397559 ! cellular respiration GO:0045333 62 61 0,000 0,06046297 0,06497566 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 0,000 0,06046297 0,0649378 ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,06046297 0,06489998 GO:0016054|organic acid catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,06046297 0,0648622 ! lipid transport GO:0006869 62 62 0,000 0,06142745 0,06585852 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,06142745 0,06582023 ! morphogenesis of an epithelium GO:0002009 63 62 0,000 0,06142745 0,06578198 GO:0060429|epithelium development, ! axonogenesis GO:0007409 66 62 0,000 0,06142745 0,06574378 ! regulation of cellular component biogenesis GO:0044087 63 62 0,000 0,06142745 0,06570562 ! protein import GO:0017038 62 62 0,000 0,06142745 0,06566751 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,06142745 0,06562944 ! regulation of lymphocyte activation GO:0051249 62 62 0,000 0,06142745 0,06559142 ! regulation of secretion GO:0051046 65 63 0,000 0,06239108 0,06658179 ! negative regulation of cellular component organization GO:0051129 65 63 0,000 0,06239108 0,06654326 ! glucose metabolic process GO:0006006 63 63 0,000 0,06239108 0,06650477 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,06239108 0,06646633 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,06239108 0,06642793 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,06335386 0,06741406 ! regulation of response to external stimulus GO:0032101 65 64 0,000 0,06335386 0,06737516 ! angiogenesis GO:0001525 65 64 0,000 0,06335386 0,06733631 ! regulation of cytoskeleton organization GO:0051493 66 64 0,000 0,06335386 0,0672975 ! positive regulation of protein metabolic process GO:0051247 64 64 0,000 0,06335386 0,06725873 ! anion transport GO:0006820 65 65 0,000 0,06431579 0,06824064 ! positive regulation of cellular component organization GO:0051130 65 65 0,000 0,06431579 0,06820138 ! regulation of hormone levels GO:0010817 66 65 0,000 0,06431579 0,06816216 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,06527687 0,06914096 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,06527687 0,06910125 ! DNA packaging GO:0006323 66 66 0,000 0,06527687 0,06906158 ! regulation of MAP kinase activity GO:0043405 67 66 0,000 0,06527687 0,06902196 ! polysaccharide metabolic process GO:0005976 69 66 0,000 0,06527687 0,06898238 ! negative regulation of protein metabolic process GO:0051248 66 66 0,000 0,06527687 0,06894285 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 0,000 0,06623711 0,06991695 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! Golgi vesicle transport GO:0048193 67 67 0,000 0,06623711 0,06987693 ! muscle contraction GO:0006936 67 67 0,000 0,06623711 0,06983695 ! striated muscle tissue development GO:0014706 69 67 0,000 0,06623711 0,06979702 ! negative regulation of cell differentiation GO:0045596 68 67 0,000 0,06623711 0,06975714 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,0671965 0,0707271 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,0671965 0,07068673 ! regulation of cell size GO:0008361 68 68 0,000 0,0671965 0,07064641 ! regulation of translation GO:0006417 69 69 0,000 0,06815505 0,07161332 ! sensory perception of sound GO:0007605 71 69 0,000 0,06815505 0,07157251 GO:0050954|sensory perception of mechanical stimulus, ! regionalization GO:0003002 70 69 0,000 0,06815505 0,07153175 ! response to nutrient levels GO:0031667 69 69 0,000 0,06815505 0,07149104 ! regulation of leukocyte activation GO:0002694 69 69 0,000 0,06815505 0,07145037 ! regulation of mitotic cell cycle GO:0007346 72 69 0,000 0,06815505 0,07140975 ! positive regulation of transport GO:0051050 71 70 0,000 0,06911275 0,07237205 ! cell part morphogenesis GO:0032990 75 70 0,000 0,06911275 0,07233095 ! wound healing GO:0042060 74 70 0,000 0,06911275 0,0722899 ! growth GO:0040007 70 70 0,000 0,06911275 0,07224889 ! muscle tissue development GO:0060537 72 70 0,000 0,06911275 0,07220794 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,06911275 0,07216703 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,07006961 0,07312474 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,07006961 0,07308336 ! regulation of cell migration GO:0030334 71 71 0,000 0,07006961 0,07304202 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,07006961 0,07300073 GO:0006874|cellular calcium ion homeostasis, ! ribosome biogenesis GO:0042254 71 71 0,000 0,07006961 0,07295949 ! regulation of cell activation GO:0050865 71 71 0,000 0,07006961 0,07291829 ! secretion by cell GO:0032940 75 72 0,000 0,07102563 0,07387146 ! muscle system process GO:0003012 72 72 0,000 0,07102563 0,0738298 ! positive regulation of hydrolase activity GO:0051345 72 72 0,000 0,07102563 0,07378818 ! sensory organ development GO:0007423 72 72 0,000 0,07102563 0,07374661 ! response to extracellular stimulus GO:0009991 72 72 0,000 0,07102563 0,07370508 ! regulation of cytokine production GO:0001817 72 72 0,000 0,07102563 0,07366361 ! electron transport chain GO:0022900 75 74 0,000 0,07293513 0,07560149 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,07293513 0,07555899 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,07388862 0,07650378 ! response to oxidative stress GO:0006979 76 75 0,000 0,07388862 0,07646083 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,07388862 0,07641792 ! positive regulation of multicellular organismal process GO:0051240 76 76 0,000 0,07484127 0,07735977 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,07579308 0,07829969 ! cell morphogenesis involved in differentiation GO:0000904 82 77 0,000 0,07579308 0,07825583 ! regulation of protein modification process GO:0031399 79 78 0,000 0,07674405 0,07919333 ! microtubule-based movement GO:0007018 82 78 0,000 0,07674405 0,07914901 ! positive regulation of protein kinase cascade GO:0010740 79 78 0,000 0,07674405 0,07910475 ! metal ion homeostasis GO:0055065 78 78 0,000 0,07674405 0,07906053 ! regulation of immune response GO:0050776 78 78 0,000 0,07674405 0,07901636 ! regulation of locomotion GO:0040012 79 79 0,000 0,07769418 0,07994996 ! nuclear transport GO:0051169 79 79 0,000 0,07769418 0,07990534 GO:0006913|nucleocytoplasmic transport, ! regulation of cell motion GO:0051270 79 79 0,000 0,07769418 0,07986078 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,07864347 0,08079148 ! neuron projection development GO:0031175 85 80 0,000 0,07864347 0,08074648 ! MAPKKK cascade GO:0000165 82 81 0,000 0,07959193 0,08167479 ! tube development GO:0035295 83 81 0,000 0,07959193 0,08162934 ! lymphocyte activation GO:0046649 82 81 0,000 0,07959193 0,08158394 ! lipid catabolic process GO:0016042 82 81 0,000 0,07959193 0,08153859 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,08148633 0,08343295 ! ncRNA processing GO:0034470 83 83 0,000 0,08148633 0,08338662 ! blood vessel morphogenesis GO:0048514 84 83 0,000 0,08148633 0,08334035 ! cellular amino acid derivative metabolic process GO:0006575 87 84 0,000 0,08243228 0,08426106 ! regulation of cellular localization GO:0060341 86 85 0,000 0,08337739 0,08517989 ! nitrogen compound biosynthetic process GO:0044271 86 85 0,000 0,08337739 0,0851327 ! positive regulation of cell differentiation GO:0045597 87 85 0,000 0,08337739 0,08508556 ! positive regulation of response to stimulus GO:0048584 86 85 0,000 0,08337739 0,08503848 ! positive regulation of protein kinase activity GO:0045860 89 86 0,000 0,08432166 0,085954 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 0,000 0,08432166 0,08590648 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,08432166 0,08585902 GO:0006644|phospholipid metabolic process, ! hexose metabolic process GO:0019318 87 86 0,000 0,08432166 0,08581161 ! heart development GO:0007507 90 87 0,000 0,08526511 0,08672384 ! male gamete generation GO:0048232 90 88 0,000 0,08620772 0,08763421 GO:0007283|spermatogenesis, ! positive regulation of transferase activity GO:0051347 91 88 0,000 0,08620772 0,0875859 GO:0033674|positive regulation of kinase activity, ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,08620772 0,08753764 ! chemotaxis GO:0006935 90 89 0,000 0,08714949 0,08844522 GO:0042330|taxis, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 0,000 0,08714949 0,08839654 ! regulation of Ras protein signal transduction GO:0046578 90 90 0,000 0,08809044 0,0893018 ! brain development GO:0007420 91 90 0,000 0,08809044 0,08925271 ! negative regulation of cell cycle GO:0045786 92 91 0,000 0,08903055 0,09015566 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 0,000 0,08903055 0,09010615 ! visual perception GO:0007601 93 92 0,000 0,08996983 0,09100681 GO:0050953|sensory perception of light stimulus, ! fatty acid metabolic process GO:0006631 93 92 0,000 0,08996983 0,09095688 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 0,000 0,08996983 0,09090702 ! positive regulation of immune system process GO:0002684 92 92 0,000 0,08996983 0,0908572 ! tissue morphogenesis GO:0048729 94 93 0,000 0,09090828 0,09175464 ! regulation of response to stress GO:0080134 97 94 0,000 0,09184591 0,09265025 ! blood vessel development GO:0001568 95 94 0,000 0,09184591 0,09259956 ! pattern specification process GO:0007389 96 94 0,000 0,09184591 0,09254894 ! epidermis development GO:0008544 94 94 0,000 0,09184591 0,09249836 ! cofactor metabolic process GO:0051186 95 94 0,000 0,09184591 0,09244784 ! regulation of cell growth GO:0001558 97 96 0,000 0,09371866 0,09428138 ! vasculature development GO:0001944 97 96 0,000 0,09371866 0,09422995 ! endocytosis GO:0006897 99 98 0,000 0,09558811 0,09605719 GO:0010324|membrane invagination, ! posttranscriptional regulation of gene expression GO:0010608 98 98 0,000 0,09558811 0,09600484 ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,09558811 0,09595255 ! blood circulation GO:0008015 99 98 0,000 0,09558811 0,09590032 GO:0003013|circulatory system process, ! regulation of system process GO:0044057 98 98 0,000 0,09558811 0,09584814 ! ectoderm development GO:0007398 99 99 0,000 0,09652159 0,09673154 ! muscle organ development GO:0007517 102 100 0,000 0,09745425 0,09761314 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 0,000 0,09745425 0,09756012 ! response to other organism GO:0051707 101 100 0,000 0,09745425 0,09750716 ! hemopoiesis GO:0030097 104 100 0,000 0,09745425 0,09745425