pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-b2/out-0.05-06-0.01-300-run-b2//th1-pval-1e-01-06-th2-pval-1e-02-02-th3-pval-1e-01-01-run-b2/go_data/890-10-real-Schmidt-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 2,000 2,236E-06 5,142E-03 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 2,000 2,349E-06 2,701E-03 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 2,000 2,711E-06 2,078E-03 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 2,000 2,711E-06 1,559E-03 ! positive regulation of ligase activity GO:0051351 99 69 2,000 3,249E-06 1,495E-03 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 2,000 3,543E-06 1,358E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 3,844E-06 1,263E-03 ! regulation of ligase activity GO:0051340 114 75 2,000 4,182E-06 1,202E-03 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 2,000 5,083E-06 1,299E-03 GO:0010498|proteasomal protein catabolic process, ! interphase of mitotic cell cycle GO:0051329 156 86 2,000 6,323E-06 1,454E-03 ! interphase GO:0051325 159 88 2,000 6,777E-06 1,417E-03 ! cellular response to unfolded protein GO:0034620 19 16 1,000 2,192E-05 4,201E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! G2/M transition of mitotic cell cycle GO:0000086 33 21 1,000 3,831E-05 6,779E-03 ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 3,831E-05 6,294E-03 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 4,614E-05 7,075E-03 ! fat cell differentiation GO:0045444 37 24 1,000 5,032E-05 7,234E-03 ! DNA damage checkpoint GO:0000077 53 31 1,000 8,464E-05 0,01145195 ! mitotic cell cycle checkpoint GO:0007093 63 34 1,000 1,02E-04 0,0130397 ! DNA integrity checkpoint GO:0031570 57 34 1,000 1,02E-04 0,0123534 ! response to calcium ion GO:0051592 58 40 1,000 1,417E-04 0,01629466 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 1,000 1,639E-04 0,01795356 ! positive regulation of cell cycle GO:0045787 77 45 1,000 1,796E-04 0,01878001 ! response to UV GO:0009411 75 46 1,000 1,878E-04 0,01877571 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 1,000 2,31E-04 0,0221404 ! DNA damage response, signal transduction GO:0042770 96 56 1,000 2,787E-04 0,02564307 ! cell cycle checkpoint GO:0000075 108 64 1,000 3,642E-04 0,0322189 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 1,000 3,642E-04 0,0310256 ! response to metal ion GO:0010038 103 70 1,000 4,357E-04 0,0357895 ! positive regulation of phosphorylation GO:0042327 102 70 1,000 4,357E-04 0,03455538 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 1,000 4,609E-04 0,03533761 GO:0045937|positive regulation of phosphate metabolic process, ! response to inorganic substance GO:0010035 115 75 1,000 5,001E-04 0,03710226 ! response to unfolded protein GO:0006986 99 76 1,000 5,135E-04 0,03690579 ! positive regulation of protein modification process GO:0031401 107 78 1,000 5,408E-04 0,03769138 ! response to protein stimulus GO:0051789 111 81 1,000 5,831E-04 0,03944284 ! response to light stimulus GO:0009416 153 96 1,000 8,178E-04 0,05374106 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 2,286E-03 0,14606507 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 2,286E-03 0,14211737 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 2,286E-03 0,13837744 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 2,286E-03 0,1348293 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 2,286E-03 0,13145856 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 2,286E-03 0,12825226 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 2,286E-03 0,12519863 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 2,286E-03 0,12228704 ! sleep GO:0030431 11 5 0,000 2,286E-03 0,11950779 ! negative regulation of bone resorption GO:0045779 10 5 0,000 2,286E-03 0,11685206 ! nucleotide-sugar transport GO:0015780 8 5 0,000 2,286E-03 0,1143118 ! regulation of interferon-beta production GO:0032648 5 5 0,000 2,286E-03 0,11187963 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 2,286E-03 0,1095488 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 2,286E-03 0,10731311 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 2,286E-03 0,10516685 ! tongue development GO:0043586 6 5 0,000 2,286E-03 0,10310476 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 2,286E-03 0,10112197 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 2,286E-03 0,09921401 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 2,286E-03 0,09737671 ! cobalt ion transport GO:0006824 9 5 0,000 2,286E-03 0,09560623 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 2,286E-03 0,09389897 ! SMAD protein complex assembly GO:0007183 9 5 0,000 2,286E-03 0,09225162 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 2,286E-03 0,09066108 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 2,286E-03 0,08912445 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 2,286E-03 0,08763904 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 2,286E-03 0,08620234 ! embryonic camera-type eye development GO:0031076 8 5 0,000 2,286E-03 0,08481198 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 2,286E-03 0,08346576 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 2,286E-03 0,0821616 ! adaptation of signaling pathway GO:0022401 7 5 0,000 2,286E-03 0,08089758 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 2,286E-03 0,07967186 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 2,286E-03 0,07848273 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 2,286E-03 0,07732857 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 2,286E-03 0,07620786 ! positive regulation of histone modification GO:0031058 5 5 0,000 2,286E-03 0,07511918 ! malate metabolic process GO:0006108 7 5 0,000 2,286E-03 0,07406116 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 2,286E-03 0,07303254 ! behavioral response to pain GO:0048266 7 5 0,000 2,286E-03 0,07203209 ! clathrin coat assembly GO:0048268 11 5 0,000 2,286E-03 0,07105868 ! phototransduction, visible light GO:0007603 6 5 0,000 2,286E-03 0,07011123 ! regulation of dopamine uptake GO:0051584 9 5 0,000 2,286E-03 0,06918872 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 2,286E-03 0,06829016 ! mating behavior GO:0007617 6 5 0,000 2,286E-03 0,06741465 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 2,286E-03 0,0665613 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 2,286E-03 0,06572928 ! rhythmic behavior GO:0007622 12 5 0,000 2,286E-03 0,06491781 ! copulation GO:0007620 7 5 0,000 2,286E-03 0,06412613 ! glial cell fate commitment GO:0021781 12 5 0,000 2,286E-03 0,06335353 ! protein maturation by protein folding GO:0022417 12 5 0,000 2,286E-03 0,06259932 ! embryonic hemopoiesis GO:0035162 10 5 0,000 2,286E-03 0,06186285 ! regulation of potassium ion transport GO:0043266 9 5 0,000 2,286E-03 0,06114352 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 2,286E-03 0,06044072 ! apoptotic cell clearance GO:0043277 13 5 0,000 2,286E-03 0,05975389 ! lipoprotein particle clearance GO:0034381 9 5 0,000 2,286E-03 0,0590825 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 2,286E-03 0,05842603 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 2,286E-03 0,05778398 ! response to protozoan GO:0001562 9 5 0,000 2,286E-03 0,0571559 ! positive regulation of glycolysis GO:0045821 11 5 0,000 2,286E-03 0,05654132 ! lymph vessel development GO:0001945 7 5 0,000 2,286E-03 0,05593981 ! endochondral ossification GO:0001958 12 5 0,000 2,286E-03 0,05535097 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 2,286E-03 0,0547744 ! parathyroid gland development GO:0060017 8 5 0,000 2,286E-03 0,05420972 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 2,286E-03 0,05365656 ! anagen GO:0042640 6 5 0,000 2,286E-03 0,05311457 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 2,286E-03 0,05258343 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 2,286E-03 0,0520628 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 2,286E-03 0,05155238 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 2,286E-03 0,05105187 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 2,286E-03 0,05056099 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 2,286E-03 0,05007945 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 2,286E-03 0,04960701 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 2,286E-03 0,04914339 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 2,286E-03 0,04868836 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 2,286E-03 0,04824168 ! cardiac muscle fiber development GO:0048739 7 5 0,000 2,286E-03 0,04780311 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 2,286E-03 0,04737246 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 2,286E-03 0,04694949 ! neutrophil mediated immunity GO:0002446 6 5 0,000 2,286E-03 0,04653401 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 2,286E-03 0,04612581 ! ovulation GO:0030728 6 5 0,000 2,286E-03 0,04572472 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 2,286E-03 0,04533054 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 2,286E-03 0,0449431 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 2,286E-03 0,04456223 ! response to pH GO:0009268 9 5 0,000 2,286E-03 0,04418775 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 2,286E-03 0,04381952 ! proline biosynthetic process GO:0006561 6 5 0,000 2,286E-03 0,04345738 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 2,286E-03 0,04310117 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 2,286E-03 0,04275075 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 2,286E-03 0,04240599 ! polyol catabolic process GO:0046174 7 5 0,000 2,286E-03 0,04206674 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 2,286E-03 0,04173288 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 2,286E-03 0,04140427 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 2,286E-03 0,0410808 ! sister chromatid cohesion GO:0007062 9 5 0,000 2,286E-03 0,04076235 ! nerve growth factor processing GO:0032455 7 5 0,000 2,286E-03 0,04044879 ! urea metabolic process GO:0019627 6 5 0,000 2,286E-03 0,04014002 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 2,286E-03 0,03983593 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 2,286E-03 0,03953641 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 2,286E-03 0,03924136 ! neutrophil activation GO:0042119 5 5 0,000 2,286E-03 0,03895069 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 2,286E-03 0,03866428 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 2,286E-03 0,03838206 ! response to food GO:0032094 5 5 0,000 2,286E-03 0,03810393 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 2,286E-03 0,0378298 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 2,286E-03 0,03755959 ! paraxial mesoderm development GO:0048339 9 5 0,000 2,286E-03 0,03729321 ! forebrain neuron development GO:0021884 7 5 0,000 2,286E-03 0,03703058 ! melanosome organization GO:0032438 7 5 0,000 2,286E-03 0,03677163 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 2,286E-03 0,03651627 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 2,286E-03 0,03626443 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 2,286E-03 0,03601605 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 2,286E-03 0,03577104 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 2,286E-03 0,03552934 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 2,286E-03 0,03529089 ! nucleoside transport GO:0015858 6 5 0,000 2,286E-03 0,03505562 ! nucleoside salvage GO:0043174 7 5 0,000 2,286E-03 0,03482346 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 2,286E-03 0,03459436 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 2,286E-03 0,03436825 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 2,286E-03 0,03414508 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 2,286E-03 0,03392479 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 2,286E-03 0,03370732 ! early endosome to late endosome transport GO:0045022 11 5 0,000 2,286E-03 0,03349263 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 2,286E-03 0,03328065 ! depyrimidination GO:0045008 8 5 0,000 2,286E-03 0,03307134 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 2,286E-03 0,03286464 ! 5S class rRNA transcription GO:0042791 8 5 0,000 2,286E-03 0,03266051 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 2,286E-03 0,0324589 ! regulation of centrosome cycle GO:0046605 7 5 0,000 2,286E-03 0,03225977 ! neuronal ion channel clustering GO:0045161 7 5 0,000 2,286E-03 0,03206306 ! sodium ion homeostasis GO:0055078 6 5 0,000 2,286E-03 0,03186874 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 2,286E-03 0,03167676 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 2,286E-03 0,03148708 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 2,286E-03 0,03129966 ! monocyte differentiation GO:0030224 8 5 0,000 2,286E-03 0,03111445 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 2,286E-03 0,03093143 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 2,286E-03 0,03075054 ! centrosome duplication GO:0051298 5 5 0,000 2,286E-03 0,03057176 ! response to UV-C GO:0010225 6 5 0,000 2,286E-03 0,03039504 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 2,286E-03 0,03022036 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 2,286E-03 0,03004767 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 2,286E-03 0,02987695 ! regulation of dendrite development GO:0050773 12 5 0,000 2,286E-03 0,02970815 ! peptidyl-arginine modification GO:0018195 7 5 0,000 2,286E-03 0,02954125 ! positive regulation of organ growth GO:0046622 6 5 0,000 2,286E-03 0,02937622 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 2,286E-03 0,02921301 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 2,286E-03 0,02905162 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 2,286E-03 0,02889199 ! regulation of dopamine secretion GO:0014059 12 5 0,000 2,286E-03 0,02873411 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 2,286E-03 0,02857795 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 2,286E-03 0,02842347 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 2,286E-03 0,02827066 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 2,286E-03 0,02811948 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 2,286E-03 0,02796991 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 2,286E-03 0,02782192 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 2,286E-03 0,02767549 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 2,286E-03 0,02753059 ! neural tube patterning GO:0021532 6 5 0,000 2,286E-03 0,0273872 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 2,286E-03 0,0272453 ! histone demethylation GO:0016577 9 5 0,000 2,286E-03 0,02710486 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 2,286E-03 0,02696586 ! regulation of sterol transport GO:0032371 7 5 0,000 2,286E-03 0,02682828 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 2,286E-03 0,02669209 ! enteric nervous system development GO:0048484 8 5 0,000 2,286E-03 0,02655729 ! establishment of planar polarity GO:0001736 6 5 0,000 2,286E-03 0,02642383 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 2,286E-03 0,02629171 ! muscle cell proliferation GO:0033002 8 5 0,000 2,286E-03 0,02616091 ! transcription termination GO:0006353 8 5 0,000 2,286E-03 0,0260314 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 2,286E-03 0,02590317 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 2,286E-03 0,02577619 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 2,286E-03 0,02565045 ! regulation of respiratory burst GO:0060263 8 5 0,000 2,286E-03 0,02552593 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 2,286E-03 0,02540262 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 2,286E-03 0,02528049 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 2,286E-03 0,02515953 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 2,286E-03 0,02503973 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 2,286E-03 0,02492105 ! apical protein localization GO:0045176 6 5 0,000 2,286E-03 0,0248035 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 2,286E-03 0,02468705 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 2,286E-03 0,02457169 ! galactolipid metabolic process GO:0019374 7 5 0,000 2,286E-03 0,02445741 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 2,286E-03 0,02434418 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 2,286E-03 0,02423199 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 2,286E-03 0,02412084 ! triglyceride catabolic process GO:0019433 6 5 0,000 2,286E-03 0,0240107 ! glial cell migration GO:0008347 10 5 0,000 2,286E-03 0,02390156 ! determination of adult lifespan GO:0008340 8 5 0,000 2,286E-03 0,02379341 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 2,286E-03 0,02368623 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 2,286E-03 0,02358001 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 2,286E-03 0,02347474 ! somatic stem cell maintenance GO:0035019 13 5 0,000 2,286E-03 0,02337041 ! cerebellar cortex formation GO:0021697 6 5 0,000 2,286E-03 0,023267 ! neural plate development GO:0001840 6 5 0,000 2,286E-03 0,0231645 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 2,286E-03 0,02306291 ! regulation of sensory perception GO:0051931 6 5 0,000 2,286E-03 0,02296219 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 2,286E-03 0,02286236 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 2,286E-03 0,02276339 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 2,286E-03 0,02266527 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 2,286E-03 0,02256799 ! sensory cilium assembly GO:0035058 6 5 0,000 2,286E-03 0,02247155 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 2,286E-03 0,02237593 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 2,286E-03 0,02228111 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 2,286E-03 0,0221871 ! spindle assembly GO:0051225 5 5 0,000 2,286E-03 0,02209388 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 2,286E-03 0,02200143 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 2,286E-03 0,02190976 ! protein amino acid prenylation GO:0018346 9 5 0,000 2,286E-03 0,02181885 ! organ regeneration GO:0031100 7 5 0,000 2,286E-03 0,02172869 ! NAD biosynthetic process GO:0009435 7 5 0,000 2,286E-03 0,02163927 ! carnitine metabolic process GO:0009437 5 5 0,000 2,286E-03 0,02155058 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 2,286E-03 0,02146262 ! cellular anion homeostasis GO:0030002 6 5 0,000 2,286E-03 0,02137538 GO:0055081|anion homeostasis, ! tRNA transcription GO:0009304 11 6 0,000 2,743E-03 0,02554149 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 2,743E-03 0,0254385 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 2,743E-03 0,02533634 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 2,743E-03 0,02523499 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 2,743E-03 0,02513445 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 2,743E-03 0,02503471 ! regulation of helicase activity GO:0051095 11 6 0,000 2,743E-03 0,02493576 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 2,743E-03 0,02483759 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 2,743E-03 0,02474019 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 2,743E-03 0,02464355 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 2,743E-03 0,02454766 ! positive regulation of axon extension GO:0045773 8 6 0,000 2,743E-03 0,02445251 ! prostate gland development GO:0030850 9 6 0,000 2,743E-03 0,0243581 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 2,743E-03 0,02426441 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 2,743E-03 0,02417145 ! forebrain neuron differentiation GO:0021879 9 6 0,000 2,743E-03 0,02407919 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 2,743E-03 0,02398763 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 2,743E-03 0,02389677 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 2,743E-03 0,0238066 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 2,743E-03 0,0237171 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 2,743E-03 0,02362827 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 2,743E-03 0,0235401 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 2,743E-03 0,02345259 ! neuron adhesion GO:0007158 9 6 0,000 2,743E-03 0,02336573 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 2,743E-03 0,02327951 ! establishment of tissue polarity GO:0007164 7 6 0,000 2,743E-03 0,02319393 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 2,743E-03 0,02310897 ! signal peptide processing GO:0006465 8 6 0,000 2,743E-03 0,02302463 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 2,743E-03 0,0229409 ! mRNA stabilization GO:0048255 15 6 0,000 2,743E-03 0,02285778 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 2,743E-03 0,02277526 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 2,743E-03 0,02269334 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 2,743E-03 0,022612 ! opsonization GO:0008228 8 6 0,000 2,743E-03 0,02253124 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 2,743E-03 0,02245106 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 2,743E-03 0,02237145 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 2,743E-03 0,0222924 ! protein amino acid dealkylation GO:0008214 11 6 0,000 2,743E-03 0,0222139 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 2,743E-03 0,02213596 ! photoreceptor cell development GO:0042461 10 6 0,000 2,743E-03 0,02205856 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 2,743E-03 0,0219817 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 2,743E-03 0,02190537 ! mechanosensory behavior GO:0007638 8 6 0,000 2,743E-03 0,02182958 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 2,743E-03 0,0217543 ! negative regulation of endocytosis GO:0045806 8 6 0,000 2,743E-03 0,02167955 ! response to interferon-gamma GO:0034341 12 6 0,000 2,743E-03 0,0216053 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 2,743E-03 0,02153156 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 2,743E-03 0,02145833 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 2,743E-03 0,02138559 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 2,743E-03 0,02131334 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 2,743E-03 0,02124158 ! cGMP-mediated signaling GO:0019934 10 6 0,000 2,743E-03 0,02117029 ! activation of MAPKKK activity GO:0000185 10 6 0,000 2,743E-03 0,02109949 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 2,743E-03 0,02102916 ! thymic T cell selection GO:0045061 12 6 0,000 2,743E-03 0,0209593 ! protein lipoylation GO:0009249 10 6 0,000 2,743E-03 0,02088989 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 2,743E-03 0,02082095 ! pigment granule organization GO:0048753 11 6 0,000 2,743E-03 0,02075246 ! drug transport GO:0015893 6 6 0,000 2,743E-03 0,02068442 ! cysteine metabolic process GO:0006534 7 6 0,000 2,743E-03 0,02061682 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 2,743E-03 0,02054967 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 2,743E-03 0,02048295 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 2,743E-03 0,02041666 ! histidine metabolic process GO:0006547 6 6 0,000 2,743E-03 0,0203508 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 2,743E-03 0,02028536 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 2,743E-03 0,02022035 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 2,743E-03 0,02015574 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 2,743E-03 0,02009155 ! adenohypophysis development GO:0021984 10 6 0,000 2,743E-03 0,02002777 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 2,743E-03 0,01996439 ! hyperosmotic response GO:0006972 8 6 0,000 2,743E-03 0,01990141 ! microtubule nucleation GO:0007020 10 6 0,000 2,743E-03 0,01983883 ! ER overload response GO:0006983 7 6 0,000 2,743E-03 0,01977664 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 2,743E-03 0,01971484 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 2,743E-03 0,01965342 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 2,743E-03 0,01959238 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 2,743E-03 0,01953173 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 2,743E-03 0,01947144 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 2,743E-03 0,01941153 ! response to dietary excess GO:0002021 7 6 0,000 2,743E-03 0,01935199 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 2,743E-03 0,01929281 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 2,743E-03 0,01923399 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 2,743E-03 0,01917553 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 2,743E-03 0,01911742 ! glycerol ether catabolic process GO:0044269 8 6 0,000 2,743E-03 0,01905966 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 2,743E-03 0,01900225 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 2,743E-03 0,01894519 ! neuron apoptosis GO:0051402 8 6 0,000 2,743E-03 0,01888847 ! organic alcohol transport GO:0015850 9 6 0,000 2,743E-03 0,01883208 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 2,743E-03 0,01877604 ! T cell mediated immunity GO:0002456 12 6 0,000 2,743E-03 0,01872032 ! male sex determination GO:0030238 9 6 0,000 2,743E-03 0,01866493 ! carnitine transport GO:0015879 8 6 0,000 2,743E-03 0,01860988 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 2,743E-03 0,01855514 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 2,743E-03 0,01850073 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 2,743E-03 0,01844663 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 2,743E-03 0,01839285 ! positive regulation of exocytosis GO:0045921 6 6 0,000 2,743E-03 0,01833938 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 2,743E-03 0,01828623 ! parturition GO:0007567 12 6 0,000 2,743E-03 0,01823338 ! negative regulation of translational initiation GO:0045947 7 6 0,000 2,743E-03 0,01818083 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 2,743E-03 0,01812859 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 2,743E-03 0,01807664 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 2,743E-03 0,01802499 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 2,743E-03 0,01797364 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 2,743E-03 0,01792258 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 2,743E-03 0,01787181 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 2,743E-03 0,01782132 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 2,743E-03 0,01777112 ! macrophage differentiation GO:0030225 10 6 0,000 2,743E-03 0,0177212 ! astrocyte development GO:0014002 14 6 0,000 2,743E-03 0,01767156 ! hyaluronan metabolic process GO:0030212 6 6 0,000 2,743E-03 0,0176222 ! purine base biosynthetic process GO:0009113 14 6 0,000 2,743E-03 0,01757311 ! interaction with symbiont GO:0051702 8 6 0,000 2,743E-03 0,0175243 ! anterograde axon cargo transport GO:0008089 8 6 0,000 2,743E-03 0,01747576 ! skeletal muscle contraction GO:0003009 6 6 0,000 2,743E-03 0,01742748 ! eating behavior GO:0042755 6 6 0,000 2,743E-03 0,01737947 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 2,743E-03 0,01733172 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 2,743E-03 0,01728424 ! response to copper ion GO:0046688 9 6 0,000 2,743E-03 0,01723702 ! DNA topological change GO:0006265 8 6 0,000 2,743E-03 0,01719005 ! response to exogenous dsRNA GO:0043330 8 6 0,000 2,743E-03 0,01714334 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 2,743E-03 0,01709688 ! establishment of melanosome localization GO:0032401 9 6 0,000 2,743E-03 0,01705067 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 2,743E-03 0,01700471 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 2,743E-03 0,016959 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 2,743E-03 0,01691353 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 2,743E-03 0,01686831 ! nucleoside catabolic process GO:0009164 6 6 0,000 2,743E-03 0,01682333 ! gas homeostasis GO:0033483 11 6 0,000 2,743E-03 0,01677858 ! hair follicle maturation GO:0048820 7 6 0,000 2,743E-03 0,01673408 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 2,743E-03 0,01668981 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 2,743E-03 0,01664577 ! Schwann cell development GO:0014044 14 6 0,000 2,743E-03 0,01660197 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 2,743E-03 0,01655839 ! dendrite morphogenesis GO:0048813 9 6 0,000 2,743E-03 0,01651505 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 2,743E-03 0,01647193 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 2,743E-03 0,01642903 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 2,743E-03 0,01638636 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 2,743E-03 0,01634391 ! histone ubiquitination GO:0016574 7 6 0,000 2,743E-03 0,01630167 ! regulation of meiosis GO:0040020 10 6 0,000 2,743E-03 0,01625966 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 2,743E-03 0,01621786 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 2,743E-03 0,01617628 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 2,743E-03 0,01613491 ! regulation of mast cell activation GO:0033003 6 6 0,000 2,743E-03 0,01609374 ! membrane to membrane docking GO:0022614 12 6 0,000 2,743E-03 0,01605279 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 2,743E-03 0,01601205 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 2,743E-03 0,01597151 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 2,743E-03 0,01593118 ! receptor internalization GO:0031623 9 6 0,000 2,743E-03 0,01589105 ! neutrophil homeostasis GO:0001780 6 6 0,000 2,743E-03 0,01585113 ! coenzyme A metabolic process GO:0015936 9 6 0,000 2,743E-03 0,0158114 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 2,743E-03 0,01577187 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 2,743E-03 0,01573254 ! protein deubiquitination GO:0016579 8 6 0,000 2,743E-03 0,0156934 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 2,743E-03 0,01565446 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 2,743E-03 0,01561571 ! peptidyl-histidine modification GO:0018202 9 6 0,000 2,743E-03 0,01557716 ! axonal fasciculation GO:0007413 9 6 0,000 2,743E-03 0,01553879 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 2,743E-03 0,01550061 ! thiamin metabolic process GO:0006772 6 6 0,000 2,743E-03 0,01546262 ! midbrain development GO:0030901 6 6 0,000 2,743E-03 0,01542481 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 2,743E-03 0,01538719 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 2,743E-03 0,01534975 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 2,743E-03 0,01531249 ! progesterone metabolic process GO:0042448 8 6 0,000 2,743E-03 0,01527542 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 2,743E-03 0,01523852 ! glycolipid catabolic process GO:0019377 13 6 0,000 2,743E-03 0,0152018 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 2,743E-03 0,01516526 ! positive regulation of glucose import GO:0046326 6 6 0,000 2,743E-03 0,01512889 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 2,743E-03 0,0150927 ! adult feeding behavior GO:0008343 6 6 0,000 2,743E-03 0,01505668 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 2,743E-03 0,01502083 ! blastocyst growth GO:0001832 15 6 0,000 2,743E-03 0,01498515 ! pigment granule transport GO:0051904 12 6 0,000 2,743E-03 0,01494964 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 2,743E-03 0,0149143 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 2,743E-03 0,01487912 ! catecholamine transport GO:0051937 7 6 0,000 2,743E-03 0,01484411 ! organ or tissue specific immune response GO:0002251 7 6 0,000 2,743E-03 0,01480927 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 2,743E-03 0,01477459 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 2,743E-03 0,01474007 ! negative regulation of B cell activation GO:0050869 9 6 0,000 2,743E-03 0,01470571 ! protein prenylation GO:0018342 10 6 0,000 2,743E-03 0,01467151 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 2,743E-03 0,01463747 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 2,743E-03 0,01460358 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 2,743E-03 0,01456986 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 2,743E-03 0,01453629 ! positive regulation of coagulation GO:0050820 11 6 0,000 2,743E-03 0,01450287 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 3,199E-03 0,01687783 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 3,199E-03 0,0168392 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 3,199E-03 0,01680076 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 3,199E-03 0,01676249 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 3,199E-03 0,01672439 ! synaptonemal complex assembly GO:0007130 10 7 0,000 3,199E-03 0,01668647 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 3,199E-03 0,01664872 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 3,199E-03 0,01661113 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 3,199E-03 0,01657372 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 3,199E-03 0,01653648 ! reproductive behavior GO:0019098 12 7 0,000 3,199E-03 0,0164994 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 3,199E-03 0,01646249 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 3,199E-03 0,01642574 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 3,199E-03 0,01638916 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 3,199E-03 0,01635274 ! oligopeptide transport GO:0006857 11 7 0,000 3,199E-03 0,01631648 ! protein amino acid sulfation GO:0006477 9 7 0,000 3,199E-03 0,01628038 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 3,199E-03 0,01624444 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 3,199E-03 0,01620866 ! RNA methylation GO:0001510 11 7 0,000 3,199E-03 0,01617304 ! pericardium development GO:0060039 8 7 0,000 3,199E-03 0,01613757 ! macrophage chemotaxis GO:0048246 10 7 0,000 3,199E-03 0,01610226 ! fibril organization GO:0043206 13 7 0,000 3,199E-03 0,0160671 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 3,199E-03 0,0160321 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 3,199E-03 0,01599724 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 3,199E-03 0,01596254 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 3,199E-03 0,01592799 ! lipoprotein transport GO:0042953 9 7 0,000 3,199E-03 0,01589359 ! cerebral cortex cell migration GO:0021795 11 7 0,000 3,199E-03 0,01585934 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 3,199E-03 0,01582523 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 3,199E-03 0,01579127 ! estrogen metabolic process GO:0008210 14 7 0,000 3,199E-03 0,01575746 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 3,199E-03 0,01572379 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 3,199E-03 0,01569026 ! chemosensory behavior GO:0007635 9 7 0,000 3,199E-03 0,01565688 ! microtubule bundle formation GO:0001578 8 7 0,000 3,199E-03 0,01562364 ! T-helper 1 type immune response GO:0042088 11 7 0,000 3,199E-03 0,01559053 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 3,199E-03 0,01555757 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 3,199E-03 0,01552475 ! leukocyte degranulation GO:0043299 10 7 0,000 3,199E-03 0,01549207 ! bile acid and bile salt transport GO:0015721 9 7 0,000 3,199E-03 0,01545952 ! reflex GO:0060004 12 7 0,000 3,199E-03 0,01542711 ! positive regulation of isotype switching GO:0045830 15 7 0,000 3,199E-03 0,01539484 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 3,199E-03 0,0153627 ! protein-cofactor linkage GO:0018065 13 7 0,000 3,199E-03 0,01533069 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 3,199E-03 0,01529882 ! glycerolipid catabolic process GO:0046503 9 7 0,000 3,199E-03 0,01526708 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 3,199E-03 0,01523547 ! spinal cord patterning GO:0021511 7 7 0,000 3,199E-03 0,01520399 ! hemoglobin metabolic process GO:0020027 10 7 0,000 3,199E-03 0,01517264 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 3,199E-03 0,01514142 ! adrenal gland development GO:0030325 17 7 0,000 3,199E-03 0,01511033 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 3,199E-03 0,01507937 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 3,199E-03 0,01504853 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 3,199E-03 0,01501782 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 3,199E-03 0,01498724 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 3,199E-03 0,01495677 ! endosome organization GO:0007032 10 7 0,000 3,199E-03 0,01492643 ! thyroid hormone generation GO:0006590 11 7 0,000 3,199E-03 0,01489622 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 3,199E-03 0,01486613 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 3,199E-03 0,01483615 ! regulation of pigmentation during development GO:0048070 15 7 0,000 3,199E-03 0,0148063 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 3,199E-03 0,01477657 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 3,199E-03 0,01474696 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 3,199E-03 0,01471746 ! galactose metabolic process GO:0006012 10 7 0,000 3,199E-03 0,01468809 ! vesicle fusion GO:0006906 15 7 0,000 3,199E-03 0,01465883 ! intracellular pH reduction GO:0051452 10 7 0,000 3,199E-03 0,01462969 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 3,199E-03 0,01460066 ! organ growth GO:0035265 11 7 0,000 3,199E-03 0,01457175 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 3,199E-03 0,01454295 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 3,199E-03 0,01451427 ! Rac protein signal transduction GO:0016601 7 7 0,000 3,199E-03 0,01448569 ! retinol metabolic process GO:0042572 9 7 0,000 3,199E-03 0,01445723 ! behavioral fear response GO:0001662 13 7 0,000 3,199E-03 0,01442889 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 3,199E-03 0,01440065 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 3,199E-03 0,01437252 ! rRNA modification GO:0000154 12 7 0,000 3,199E-03 0,01434451 ! protein heterooligomerization GO:0051291 10 7 0,000 3,199E-03 0,0143166 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 3,199E-03 0,0142888 ! response to UV-B GO:0010224 11 7 0,000 3,199E-03 0,01426111 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 3,199E-03 0,01423353 ! protein retention in ER lumen GO:0006621 12 7 0,000 3,199E-03 0,01420605 ! intermediate filament organization GO:0045109 11 7 0,000 3,199E-03 0,01417868 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 3,199E-03 0,01415141 ! cardiac muscle cell development GO:0055013 9 7 0,000 3,199E-03 0,01412425 ! fibrinolysis GO:0042730 9 7 0,000 3,199E-03 0,01409719 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 3,199E-03 0,01407023 ! regulation of circadian rhythm GO:0042752 11 7 0,000 3,199E-03 0,01404338 ! B cell lineage commitment GO:0002326 17 7 0,000 3,199E-03 0,01401663 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 3,199E-03 0,01398999 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 3,199E-03 0,01396344 ! response to tropane GO:0014073 13 7 0,000 3,199E-03 0,01393699 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 3,199E-03 0,01391065 ! melanosome localization GO:0032400 10 7 0,000 3,199E-03 0,0138844 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 3,199E-03 0,01385825 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 3,199E-03 0,0138322 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 3,199E-03 0,01380625 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 3,199E-03 0,0137804 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 3,199E-03 0,01375464 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 3,199E-03 0,01372898 ! mast cell activation GO:0045576 9 7 0,000 3,199E-03 0,01370341 ! multicellular organismal aging GO:0010259 11 7 0,000 3,199E-03 0,01367794 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 3,199E-03 0,01365256 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 3,199E-03 0,01362728 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 3,199E-03 0,01360209 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 3,199E-03 0,013577 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 3,199E-03 0,01355199 ! establishment of nucleus localization GO:0040023 13 7 0,000 3,199E-03 0,01352708 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 3,199E-03 0,01350226 ! T cell lineage commitment GO:0002360 12 7 0,000 3,199E-03 0,01347753 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 3,199E-03 0,01345289 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 3,199E-03 0,01342834 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 3,199E-03 0,01340388 ! regulation of lipid transport GO:0032368 13 7 0,000 3,199E-03 0,01337951 ! response to tumor cell GO:0002347 12 7 0,000 3,199E-03 0,01335523 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 3,199E-03 0,01333104 ! neuroblast proliferation GO:0007405 13 7 0,000 3,199E-03 0,01330693 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 3,199E-03 0,01328291 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 3,199E-03 0,01325898 ! peptidyl-threonine modification GO:0018210 18 7 0,000 3,199E-03 0,01323513 ! diuresis GO:0030146 12 7 0,000 3,199E-03 0,01321137 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 3,199E-03 0,01318769 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 3,199E-03 0,0131641 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 3,199E-03 0,01314059 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 3,199E-03 0,01311717 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 3,199E-03 0,01309383 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 3,199E-03 0,01307057 ! melanin biosynthetic process GO:0042438 8 7 0,000 3,199E-03 0,0130474 ! regulation of synaptogenesis GO:0051963 10 7 0,000 3,199E-03 0,01302431 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 3,199E-03 0,01300129 ! dopamine biosynthetic process GO:0042416 15 7 0,000 3,199E-03 0,01297836 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 3,199E-03 0,01295551 ! lymph node development GO:0048535 9 7 0,000 3,199E-03 0,01293275 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 3,199E-03 0,01291006 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 3,199E-03 0,01288745 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 3,199E-03 0,01286492 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 3,199E-03 0,01284246 ! endosome to lysosome transport GO:0008333 10 7 0,000 3,199E-03 0,01282009 ! ATP catabolic process GO:0006200 10 7 0,000 3,199E-03 0,0127978 ! establishment of pigment granule localization GO:0051905 13 7 0,000 3,199E-03 0,01277558 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 3,199E-03 0,01275344 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 3,199E-03 0,01273137 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 3,199E-03 0,01270938 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 3,199E-03 0,01268747 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 3,199E-03 0,01266563 ! muscle adaptation GO:0043500 12 7 0,000 3,199E-03 0,01264387 ! amino sugar catabolic process GO:0046348 9 7 0,000 3,199E-03 0,01262218 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 3,199E-03 0,01260057 ! retina homeostasis GO:0001895 9 7 0,000 3,199E-03 0,01257903 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 3,199E-03 0,01255756 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 3,199E-03 0,01253617 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 3,199E-03 0,01251485 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 3,199E-03 0,0124936 ! behavioral response to nicotine GO:0035095 11 7 0,000 3,199E-03 0,01247243 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 3,199E-03 0,01245132 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 3,199E-03 0,01243029 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 3,656E-03 0,01417925 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 3,656E-03 0,01415538 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 3,656E-03 0,01413159 ! axon extension GO:0048675 11 8 0,000 3,656E-03 0,01410788 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 3,656E-03 0,01408425 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 3,656E-03 0,0140607 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 3,656E-03 0,01403722 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 3,656E-03 0,01401383 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 3,656E-03 0,01399051 ! cell proliferation in forebrain GO:0021846 10 8 0,000 3,656E-03 0,01396727 ! positive regulation of B cell proliferation GO:0030890 11 8 0,000 3,656E-03 0,01394411 ! phosphate transport GO:0006817 10 8 0,000 3,656E-03 0,01392102 ! N-glycan processing GO:0006491 12 8 0,000 3,656E-03 0,01389801 ! Golgi to endosome transport GO:0006895 16 8 0,000 3,656E-03 0,01387508 ! UTP metabolic process GO:0046051 8 8 0,000 3,656E-03 0,01385222 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 3,656E-03 0,01382943 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 3,656E-03 0,01380673 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 3,656E-03 0,01378409 ! neurotransmitter uptake GO:0001504 10 8 0,000 3,656E-03 0,01376153 ! succinate metabolic process GO:0006105 14 8 0,000 3,656E-03 0,01373905 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 3,656E-03 0,01371663 ! smoothened signaling pathway GO:0007224 8 8 0,000 3,656E-03 0,01369429 ! membrane hyperpolarization GO:0060081 10 8 0,000 3,656E-03 0,01367203 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 3,656E-03 0,01364983 ! keratinocyte proliferation GO:0043616 12 8 0,000 3,656E-03 0,01362771 ! middle ear morphogenesis GO:0042474 9 8 0,000 3,656E-03 0,01360566 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 3,656E-03 0,01358368 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 3,656E-03 0,01356177 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 3,656E-03 0,01353993 ! ganglioside metabolic process GO:0001573 15 8 0,000 3,656E-03 0,01351816 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 3,656E-03 0,01349646 ! pseudouridine synthesis GO:0001522 9 8 0,000 3,656E-03 0,01347483 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 3,656E-03 0,01345327 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 3,656E-03 0,01343178 ! endothelial cell differentiation GO:0045446 14 8 0,000 3,656E-03 0,01341036 ! ceramide biosynthetic process GO:0046513 9 8 0,000 3,656E-03 0,01338901 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 3,656E-03 0,01336772 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 0,000 3,656E-03 0,0133465 ! astrocyte differentiation GO:0048708 16 8 0,000 3,656E-03 0,01332535 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 3,656E-03 0,01330427 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 3,656E-03 0,01328325 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 3,656E-03 0,0132623 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 3,656E-03 0,01324141 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 3,656E-03 0,01322059 ! melanin metabolic process GO:0006582 12 8 0,000 3,656E-03 0,01319984 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 3,656E-03 0,01317915 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 3,656E-03 0,01315852 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 3,656E-03 0,01313796 ! macrophage activation GO:0042116 12 8 0,000 3,656E-03 0,01311747 ! regulation of type I interferon production GO:0032479 8 8 0,000 3,656E-03 0,01309703 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 3,656E-03 0,01307667 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 3,656E-03 0,01305636 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 3,656E-03 0,01303612 ! regulation of vascular permeability GO:0043114 12 8 0,000 3,656E-03 0,01301594 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 3,656E-03 0,01299582 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 3,656E-03 0,01297577 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 3,656E-03 0,01295577 ! ruffle organization GO:0031529 11 8 0,000 3,656E-03 0,01293584 ! osteoblast development GO:0002076 13 8 0,000 3,656E-03 0,01291597 ! lens development in camera-type eye GO:0002088 10 8 0,000 3,656E-03 0,01289616 ! positive regulation of vasodilation GO:0045909 12 8 0,000 3,656E-03 0,01287641 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 3,656E-03 0,01285672 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 3,656E-03 0,01283709 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 3,656E-03 0,01281752 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 3,656E-03 0,01279802 ! Schwann cell differentiation GO:0014037 17 8 0,000 3,656E-03 0,01277857 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 3,656E-03 0,01275918 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 3,656E-03 0,01273984 ! regulation of gliogenesis GO:0014013 20 8 0,000 3,656E-03 0,01272057 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 3,656E-03 0,01270135 ! oligodendrocyte development GO:0014003 8 8 0,000 3,656E-03 0,0126822 ! segment specification GO:0007379 10 8 0,000 3,656E-03 0,0126631 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 3,656E-03 0,01264405 ! cellular extravasation GO:0045123 11 8 0,000 3,656E-03 0,01262507 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 3,656E-03 0,01260614 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 3,656E-03 0,01258727 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 3,656E-03 0,01256846 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 3,656E-03 0,0125497 ! snRNA metabolic process GO:0016073 10 8 0,000 3,656E-03 0,01253099 GO:0016180|snRNA processing, ! phosphoinositide 3-kinase cascade GO:0014065 23 8 0,000 3,656E-03 0,01251235 ! regulation of interleukin-4 production GO:0032673 16 8 0,000 3,656E-03 0,01249375 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 3,656E-03 0,01247522 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 3,656E-03 0,01245674 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 3,656E-03 0,01243831 ! nucleosome disassembly GO:0006337 12 8 0,000 3,656E-03 0,01241994 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 3,656E-03 0,01240162 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 3,656E-03 0,01238335 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 3,656E-03 0,01236514 ! icosanoid secretion GO:0032309 12 8 0,000 3,656E-03 0,01234698 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 3,656E-03 0,01232888 ! leukocyte activation during immune response GO:0002366 13 8 0,000 3,656E-03 0,01231083 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 3,656E-03 0,01229283 ! cerebellum morphogenesis GO:0021587 9 8 0,000 3,656E-03 0,01227489 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 3,656E-03 0,01225699 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 3,656E-03 0,01223915 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 3,656E-03 0,01222136 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 3,656E-03 0,01220362 ! sterol catabolic process GO:0016127 9 8 0,000 3,656E-03 0,01218594 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 3,656E-03 0,0121683 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 3,656E-03 0,01215072 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 3,656E-03 0,01213318 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 3,656E-03 0,0121157 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 3,656E-03 0,01209827 ! prophase GO:0051324 11 8 0,000 3,656E-03 0,01208089 ! S phase GO:0051320 8 8 0,000 3,656E-03 0,01206355 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 3,656E-03 0,01204627 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 3,656E-03 0,01202904 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 3,656E-03 0,01201185 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 3,656E-03 0,01199472 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 3,656E-03 0,01197763 ! hormone catabolic process GO:0042447 13 8 0,000 3,656E-03 0,01196059 ! quaternary ammonium group transport GO:0015697 10 8 0,000 3,656E-03 0,0119436 ! myeloid cell homeostasis GO:0002262 8 8 0,000 3,656E-03 0,01192666 ! regulation of fibrinolysis GO:0051917 13 8 0,000 3,656E-03 0,01190977 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 3,656E-03 0,01189292 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 3,656E-03 0,01187612 ! regulation of telomere maintenance GO:0032204 10 8 0,000 3,656E-03 0,01185937 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 3,656E-03 0,01184267 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 3,656E-03 0,01182601 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 3,656E-03 0,01180941 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 3,656E-03 0,01179284 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 3,656E-03 0,01177633 ! lamellipodium assembly GO:0030032 9 8 0,000 3,656E-03 0,01175986 ! regulation of embryonic development GO:0045995 16 8 0,000 3,656E-03 0,01174343 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 3,656E-03 0,01172705 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 3,656E-03 0,01171072 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 3,656E-03 0,01169443 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 4,112E-03 0,01313533 ! regulation of developmental growth GO:0048638 13 9 0,000 4,112E-03 0,01311711 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 4,112E-03 0,01309895 ! telencephalon cell migration GO:0022029 16 9 0,000 4,112E-03 0,01308083 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 4,112E-03 0,01306276 ! pentose-phosphate shunt GO:0006098 12 9 0,000 4,112E-03 0,01304474 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 4,112E-03 0,01302678 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 4,112E-03 0,01300886 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 4,112E-03 0,01299099 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 4,112E-03 0,01297317 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 4,112E-03 0,0129554 ! GTP metabolic process GO:0046039 9 9 0,000 4,112E-03 0,01293767 ! elastic fiber assembly GO:0048251 13 9 0,000 4,112E-03 0,01292 ! social behavior GO:0035176 14 9 0,000 4,112E-03 0,01290237 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 4,112E-03 0,0128848 ! artery development GO:0060840 19 9 0,000 4,112E-03 0,01286727 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 4,112E-03 0,01284978 ! regulation of glycolysis GO:0006110 15 9 0,000 4,112E-03 0,01283235 ! response to pain GO:0048265 16 9 0,000 4,112E-03 0,01281496 ! protein complex disassembly GO:0043241 17 9 0,000 4,112E-03 0,01279762 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 4,112E-03 0,01278032 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 4,112E-03 0,01276308 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 4,112E-03 0,01274588 ! lung alveolus development GO:0048286 17 9 0,000 4,112E-03 0,01272872 ! ciliary or flagellar motility GO:0001539 10 9 0,000 4,112E-03 0,01271161 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 4,112E-03 0,01269455 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 4,112E-03 0,01267753 ! regulation of exit from mitosis GO:0007096 12 9 0,000 4,112E-03 0,01266056 ! ventral spinal cord development GO:0021517 11 9 0,000 4,112E-03 0,01264364 ! protein targeting to ER GO:0045047 19 9 0,000 4,112E-03 0,01262676 ! T cell selection GO:0045058 18 9 0,000 4,112E-03 0,01260992 ! endoderm development GO:0007492 12 9 0,000 4,112E-03 0,01259313 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 4,112E-03 0,01257638 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 4,112E-03 0,01255968 ! arginine catabolic process GO:0006527 10 9 0,000 4,112E-03 0,01254302 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 4,112E-03 0,01252641 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 4,112E-03 0,01250984 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 4,112E-03 0,01249332 ! phosphagen metabolic process GO:0006599 12 9 0,000 4,112E-03 0,01247683 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 4,112E-03 0,0124604 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 4,112E-03 0,012444 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 4,112E-03 0,01242765 ! regulation of stress fiber formation GO:0051492 20 9 0,000 4,112E-03 0,01241134 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 4,112E-03 0,01239507 ! mannose metabolic process GO:0006013 9 9 0,000 4,112E-03 0,01237885 ! substrate-bound cell migration GO:0006929 10 9 0,000 4,112E-03 0,01236267 ! receptor clustering GO:0043113 15 9 0,000 4,112E-03 0,01234653 ! epithelial cell development GO:0002064 10 9 0,000 4,112E-03 0,01233043 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 4,112E-03 0,01231437 ! retinoic acid metabolic process GO:0042573 11 9 0,000 4,112E-03 0,01229836 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 4,112E-03 0,01228239 ! positive regulation of translational initiation GO:0045948 10 9 0,000 4,112E-03 0,01226646 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 4,112E-03 0,01225057 ! motor axon guidance GO:0008045 14 9 0,000 4,112E-03 0,01223472 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 4,112E-03 0,01221891 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 4,112E-03 0,01220315 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 4,112E-03 0,01218742 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 4,112E-03 0,01217174 ! blastoderm segmentation GO:0007350 11 9 0,000 4,112E-03 0,01215609 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 4,112E-03 0,01214049 ! DNA ligation GO:0006266 14 9 0,000 4,112E-03 0,01212492 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 4,112E-03 0,0121094 ! response to amine stimulus GO:0014075 13 9 0,000 4,112E-03 0,01209391 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 4,112E-03 0,01207847 ! erythrocyte development GO:0048821 11 9 0,000 4,112E-03 0,01206306 ! renal water homeostasis GO:0003091 14 9 0,000 4,112E-03 0,01204769 ! postreplication repair GO:0006301 11 9 0,000 4,112E-03 0,01203237 ! mRNA cleavage GO:0006379 13 9 0,000 4,112E-03 0,01201708 ! hindbrain morphogenesis GO:0021575 12 9 0,000 4,112E-03 0,01200183 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 4,112E-03 0,01198662 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 4,112E-03 0,01197144 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 4,112E-03 0,01195631 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 4,112E-03 0,01194121 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 4,112E-03 0,01192615 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 4,112E-03 0,01191113 ! acid secretion GO:0046717 14 9 0,000 4,112E-03 0,01189615 ! musculoskeletal movement GO:0050881 11 9 0,000 4,112E-03 0,01188121 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 4,112E-03 0,0118663 ! methionine biosynthetic process GO:0009086 10 9 0,000 4,112E-03 0,01185143 ! purine base metabolic process GO:0006144 18 9 0,000 4,112E-03 0,0118366 ! oocyte differentiation GO:0009994 12 9 0,000 4,112E-03 0,0118218 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 4,112E-03 0,01180704 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 4,112E-03 0,01179232 ! spleen development GO:0048536 15 9 0,000 4,112E-03 0,01177763 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 4,112E-03 0,01176298 ! anterior/posterior axis specification GO:0009948 11 9 0,000 4,112E-03 0,01174837 ! regulation of RNA splicing GO:0043484 14 9 0,000 4,112E-03 0,0117338 ! detection of calcium ion GO:0005513 13 9 0,000 4,112E-03 0,01171926 ! blastocyst formation GO:0001825 12 9 0,000 4,112E-03 0,01170475 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 4,112E-03 0,01169028 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 4,112E-03 0,01167585 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 4,112E-03 0,01166145 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 4,112E-03 0,01164709 ! regulation of amino acid transport GO:0051955 11 9 0,000 4,112E-03 0,01163277 ! positive regulation of amine transport GO:0051954 15 9 0,000 4,112E-03 0,01161848 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 4,112E-03 0,01160422 ! prepulse inhibition GO:0060134 14 9 0,000 4,112E-03 0,01159 ! embryonic placenta development GO:0001892 12 9 0,000 4,112E-03 0,01157581 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 4,112E-03 0,01156166 ! insulin secretion GO:0030073 17 9 0,000 4,112E-03 0,01154755 ! sequestering of metal ion GO:0051238 11 9 0,000 4,112E-03 0,01153346 ! response to nicotine GO:0035094 16 9 0,000 4,112E-03 0,01151942 ! establishment of cell polarity GO:0030010 12 9 0,000 4,112E-03 0,0115054 ! nucleus localization GO:0051647 15 9 0,000 4,112E-03 0,01149142 ! regulation of synapse organization GO:0050807 12 9 0,000 4,112E-03 0,01147748 ! localization within membrane GO:0051668 15 9 0,000 4,112E-03 0,01146356 ! negative regulation of muscle development GO:0048635 12 10 0,000 4,568E-03 0,01271933 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 4,568E-03 0,01270395 ! neuron fate specification GO:0048665 11 10 0,000 4,568E-03 0,0126886 ! negative regulation of blood pressure GO:0045776 22 10 0,000 4,568E-03 0,0126733 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 4,568E-03 0,01265803 ! thyroid gland development GO:0030878 19 10 0,000 4,568E-03 0,0126428 ! regulation of B cell proliferation GO:0030888 15 10 0,000 4,568E-03 0,0126276 ! regulation of phosphatase activity GO:0010921 21 10 0,000 4,568E-03 0,01261244 ! synapsis GO:0007129 13 10 0,000 4,568E-03 0,01259732 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 4,568E-03 0,01258223 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 4,568E-03 0,01256718 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 4,568E-03 0,01255217 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 4,568E-03 0,01253719 ! sulfate transport GO:0008272 12 10 0,000 4,568E-03 0,01252224 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 4,568E-03 0,01250734 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 4,568E-03 0,01249247 ! androgen metabolic process GO:0008209 13 10 0,000 4,568E-03 0,01247763 ! phospholipid efflux GO:0033700 16 10 0,000 4,568E-03 0,01246283 ! hippocampus development GO:0021766 19 10 0,000 4,568E-03 0,01244806 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 4,568E-03 0,01243333 ! blood vessel remodeling GO:0001974 21 10 0,000 4,568E-03 0,01241863 ! positive regulation of heart contraction GO:0045823 14 10 0,000 4,568E-03 0,01240397 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 4,568E-03 0,01238934 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 4,568E-03 0,01237475 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 4,568E-03 0,01236019 ! pathogenesis GO:0009405 13 10 0,000 4,568E-03 0,01234567 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 4,568E-03 0,01233118 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 4,568E-03 0,01231672 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 4,568E-03 0,0123023 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 4,568E-03 0,01228791 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 4,568E-03 0,01227356 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 4,568E-03 0,01225923 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 4,568E-03 0,01224495 ! melanocyte differentiation GO:0030318 15 10 0,000 4,568E-03 0,01223069 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 4,568E-03 0,01221647 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 4,568E-03 0,01220228 ! reverse cholesterol transport GO:0043691 16 10 0,000 4,568E-03 0,01218812 ! response to X-ray GO:0010165 16 10 0,000 4,568E-03 0,012174 ! B cell proliferation GO:0042100 14 10 0,000 4,568E-03 0,01215991 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 4,568E-03 0,01214585 ! regulation of sodium ion transport GO:0002028 15 10 0,000 4,568E-03 0,01213183 ! forebrain cell migration GO:0021885 17 10 0,000 4,568E-03 0,01211784 ! lipid digestion GO:0044241 15 10 0,000 4,568E-03 0,01210387 ! phagocytosis, engulfment GO:0006911 20 10 0,000 4,568E-03 0,01208995 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 4,568E-03 0,01207605 ! UV protection GO:0009650 14 10 0,000 4,568E-03 0,01206218 ! entry into host cell GO:0030260 20 10 0,000 4,568E-03 0,01204835 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 4,568E-03 0,01203455 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 4,568E-03 0,01202078 ! negative regulation of ossification GO:0030279 19 10 0,000 4,568E-03 0,01200704 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 4,568E-03 0,01199334 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 4,568E-03 0,01197966 ! regulation of bone resorption GO:0045124 24 10 0,000 4,568E-03 0,01196602 ! alpha-beta T cell activation GO:0046631 16 10 0,000 4,568E-03 0,0119524 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 4,568E-03 0,01193882 ! regulation of organ growth GO:0046620 11 10 0,000 4,568E-03 0,01192527 ! response to dsRNA GO:0043331 18 10 0,000 4,568E-03 0,01191175 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 4,568E-03 0,01189826 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 4,568E-03 0,0118848 ! embryonic axis specification GO:0000578 12 10 0,000 4,568E-03 0,01187137 ! regulation of B cell differentiation GO:0045577 16 10 0,000 4,568E-03 0,01185797 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 4,568E-03 0,0118446 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 4,568E-03 0,01183126 ! cranial nerve development GO:0021545 12 10 0,000 4,568E-03 0,01181796 ! fucose catabolic process GO:0019317 16 10 0,000 4,568E-03 0,01180468 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 4,568E-03 0,01179143 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 4,568E-03 0,01177821 ! protein sumoylation GO:0016925 12 10 0,000 4,568E-03 0,01176502 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 4,568E-03 0,01175186 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 4,568E-03 0,01173873 ! zymogen activation GO:0031638 14 10 0,000 4,568E-03 0,01172563 ! salivary gland development GO:0007431 22 10 0,000 4,568E-03 0,01171256 ! negative regulation of neurological system process GO:0031645 19 10 0,000 4,568E-03 0,01169951 ! glutathione biosynthetic process GO:0006750 11 10 0,000 4,568E-03 0,0116865 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 4,568E-03 0,01167351 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 4,568E-03 0,01166056 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 4,568E-03 0,01164763 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 4,568E-03 0,01163473 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 4,568E-03 0,01162186 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 4,568E-03 0,01160902 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 4,568E-03 0,01159621 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 4,568E-03 0,01158342 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 4,568E-03 0,01157066 ! detection of bacterium GO:0016045 10 10 0,000 4,568E-03 0,01155794 ! embryonic gut development GO:0048566 11 10 0,000 4,568E-03 0,01154523 ! activation of innate immune response GO:0002218 10 10 0,000 4,568E-03 0,01153256 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 4,568E-03 0,01151992 ! cardiac cell differentiation GO:0035051 16 10 0,000 4,568E-03 0,0115073 ! developmental induction GO:0031128 13 10 0,000 4,568E-03 0,01149471 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 4,568E-03 0,01148215 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 4,568E-03 0,01146961 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 4,568E-03 0,0114571 ! negative regulation of immune effector process GO:0002698 16 10 0,000 4,568E-03 0,01144462 ! rRNA transcription GO:0009303 17 11 0,000 5,024E-03 0,01257287 ! respiratory burst GO:0045730 14 11 0,000 5,024E-03 0,0125592 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 5,024E-03 0,01254557 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 5,024E-03 0,01253196 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 5,024E-03 0,01251838 ! virus-host interaction GO:0019048 17 11 0,000 5,024E-03 0,01250483 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 5,024E-03 0,01249131 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 5,024E-03 0,01247783 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 5,024E-03 0,01246436 ! Golgi vesicle budding GO:0048194 17 11 0,000 5,024E-03 0,01245093 ! RNA polyadenylation GO:0043631 19 11 0,000 5,024E-03 0,01243753 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 5,024E-03 0,01242416 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 5,024E-03 0,01241081 ! mating GO:0007618 14 11 0,000 5,024E-03 0,0123975 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 5,024E-03 0,01238421 ! T cell proliferation GO:0042098 20 11 0,000 5,024E-03 0,01237095 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 5,024E-03 0,01235772 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 5,024E-03 0,01234452 ! bone resorption GO:0045453 16 11 0,000 5,024E-03 0,01233134 ! regulated secretory pathway GO:0045055 14 11 0,000 5,024E-03 0,01231819 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 5,024E-03 0,01230508 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 5,024E-03 0,01229199 ! regulation of mRNA processing GO:0050684 18 11 0,000 5,024E-03 0,01227892 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 5,024E-03 0,01226589 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 5,024E-03 0,01225288 ! syncytium formation GO:0006949 15 11 0,000 5,024E-03 0,0122399 ! plasma membrane organization GO:0007009 18 11 0,000 5,024E-03 0,01222695 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 5,024E-03 0,01221402 ! focal adhesion formation GO:0048041 24 11 0,000 5,024E-03 0,01220113 ! mitotic spindle organization GO:0007052 15 11 0,000 5,024E-03 0,01218826 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 5,024E-03 0,01217541 ! regulation of intracellular pH GO:0051453 17 11 0,000 5,024E-03 0,0121626 ! membrane protein proteolysis GO:0033619 18 11 0,000 5,024E-03 0,01214981 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 5,024E-03 0,01213704 ! adult heart development GO:0007512 11 11 0,000 5,024E-03 0,01212431 ! chondrocyte differentiation GO:0002062 17 11 0,000 5,024E-03 0,0121116 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 5,024E-03 0,01209892 ! temperature homeostasis GO:0001659 16 11 0,000 5,024E-03 0,01208626 ! L-glutamate transport GO:0015813 16 11 0,000 5,024E-03 0,01207363 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 5,024E-03 0,01206103 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 5,024E-03 0,01204845 ! protein targeting to peroxisome GO:0006625 20 11 0,000 5,024E-03 0,0120359 ! stem cell development GO:0048864 29 11 0,000 5,024E-03 0,01202338 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 5,024E-03 0,01201088 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 5,024E-03 0,01199841 ! regulation of phagocytosis GO:0050764 14 11 0,000 5,024E-03 0,01198596 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 5,024E-03 0,01197354 ! vasoconstriction GO:0042310 15 11 0,000 5,024E-03 0,01196115 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 5,024E-03 0,01194878 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 5,024E-03 0,01193643 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 5,024E-03 0,01192411 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 5,024E-03 0,01191182 ! ribosome assembly GO:0042255 13 11 0,000 5,024E-03 0,01189955 ! nitric oxide metabolic process GO:0046209 14 11 0,000 5,024E-03 0,01188731 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 5,024E-03 0,01187509 ! chromatin silencing GO:0006342 19 11 0,000 5,024E-03 0,0118629 ! nucleosome positioning GO:0016584 13 11 0,000 5,024E-03 0,01185073 ! T cell homeostasis GO:0043029 20 11 0,000 5,024E-03 0,01183859 ! regulation of isotype switching GO:0045191 19 11 0,000 5,024E-03 0,01182648 ! regulation of leukocyte migration GO:0002685 24 11 0,000 5,024E-03 0,01181438 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 5,024E-03 0,01180231 ! protein-chromophore linkage GO:0018298 13 11 0,000 5,024E-03 0,01179027 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 5,024E-03 0,01177825 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 5,024E-03 0,01176626 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 5,024E-03 0,01175429 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 5,024E-03 0,01174234 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 5,024E-03 0,01173042 ! male genitalia development GO:0030539 13 11 0,000 5,024E-03 0,01171853 ! cholesterol efflux GO:0033344 19 11 0,000 5,024E-03 0,01170665 ! digestive tract morphogenesis GO:0048546 15 11 0,000 5,024E-03 0,0116948 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 5,024E-03 0,01168298 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 5,024E-03 0,01167118 ! negative regulation of glucose import GO:0046325 14 11 0,000 5,024E-03 0,0116594 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 5,024E-03 0,01164765 ! regulation of organic acid transport GO:0032890 17 11 0,000 5,024E-03 0,01163592 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 5,024E-03 0,01162421 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 5,024E-03 0,01161253 ! mRNA 3'-end processing GO:0031124 19 11 0,000 5,024E-03 0,01160087 ! lysogeny GO:0030069 18 11 0,000 5,024E-03 0,01158923 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 5,024E-03 0,01157762 ! acrosome reaction GO:0007340 13 11 0,000 5,024E-03 0,01156603 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 5,024E-03 0,01155447 ! lactation GO:0007595 20 12 0,000 5,479E-03 0,01258976 ! reproductive cellular process GO:0048610 14 12 0,000 5,479E-03 0,01257719 ! tRNA modification GO:0006400 14 12 0,000 5,479E-03 0,01256466 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 5,479E-03 0,01255214 ! positive regulation of blood pressure GO:0045777 16 12 0,000 5,479E-03 0,01253965 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 5,479E-03 0,01252719 ! 'de novo' protein folding GO:0006458 18 12 0,000 5,479E-03 0,01251475 ! dicarboxylic acid transport GO:0006835 22 12 0,000 5,479E-03 0,01250233 ! non-recombinational repair GO:0000726 19 12 0,000 5,479E-03 0,01248994 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 5,479E-03 0,01247757 ! peroxisomal transport GO:0043574 21 12 0,000 5,479E-03 0,01246523 ! cartilage condensation GO:0001502 18 12 0,000 5,479E-03 0,01245291 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 5,479E-03 0,01244062 ! cytokine biosynthetic process GO:0042089 16 12 0,000 5,479E-03 0,01242835 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 5,479E-03 0,01241611 ! heart looping GO:0001947 15 12 0,000 5,479E-03 0,01240389 ! palate development GO:0060021 15 12 0,000 5,479E-03 0,01239169 ! positive regulation of cell growth GO:0030307 16 12 0,000 5,479E-03 0,01237952 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 5,479E-03 0,01236737 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 5,479E-03 0,01235524 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 5,479E-03 0,01234314 ! arginine metabolic process GO:0006525 13 12 0,000 5,479E-03 0,01233107 ! glycoprotein catabolic process GO:0006516 19 12 0,000 5,479E-03 0,01231901 ! methionine metabolic process GO:0006555 13 12 0,000 5,479E-03 0,01230698 ! tyrosine metabolic process GO:0006570 14 12 0,000 5,479E-03 0,01229497 ! Golgi organization GO:0007030 18 12 0,000 5,479E-03 0,01228299 ! cell-cell junction assembly GO:0007043 18 12 0,000 5,479E-03 0,01227103 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 5,479E-03 0,01225909 ! monoamine transport GO:0015844 13 12 0,000 5,479E-03 0,01224718 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 5,479E-03 0,01223529 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 5,479E-03 0,01222342 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 5,479E-03 0,01221158 ! L-amino acid transport GO:0015807 20 12 0,000 5,479E-03 0,01219976 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 5,479E-03 0,01218796 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 5,479E-03 0,01217618 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 5,479E-03 0,01216443 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 5,479E-03 0,0121527 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 5,479E-03 0,01214099 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 5,479E-03 0,01212931 ! cerebellum development GO:0021549 13 12 0,000 5,479E-03 0,01211764 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 5,479E-03 0,012106 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 5,479E-03 0,01209438 ! histone acetylation GO:0016573 23 12 0,000 5,479E-03 0,01208279 ! histone methylation GO:0016571 15 12 0,000 5,479E-03 0,01207122 ! autonomic nervous system development GO:0048483 23 12 0,000 5,479E-03 0,01205966 ! gland morphogenesis GO:0022612 23 12 0,000 5,479E-03 0,01204813 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 5,479E-03 0,01203663 ! peptidyl-lysine modification GO:0018205 18 12 0,000 5,479E-03 0,01202514 ! negative regulation of protein secretion GO:0050709 20 12 0,000 5,479E-03 0,01201368 ! response to gamma radiation GO:0010332 20 12 0,000 5,479E-03 0,01200224 ! regulation of epidermis development GO:0045682 17 12 0,000 5,479E-03 0,01199082 ! intestinal absorption GO:0050892 19 12 0,000 5,479E-03 0,01197942 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 5,479E-03 0,01196804 ! cAMP biosynthetic process GO:0006171 20 12 0,000 5,479E-03 0,01195669 ! regulation of mRNA stability GO:0043488 27 12 0,000 5,479E-03 0,01194535 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 5,479E-03 0,01193404 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 5,479E-03 0,01192275 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 5,479E-03 0,01191148 ! RNA 3'-end processing GO:0031123 20 12 0,000 5,479E-03 0,01190024 ! microspike assembly GO:0030035 23 12 0,000 5,479E-03 0,01188901 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 5,479E-03 0,0118778 ! response to cold GO:0009409 14 12 0,000 5,479E-03 0,01186662 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 5,935E-03 0,01284084 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 5,935E-03 0,01282877 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 5,935E-03 0,01281673 ! cGMP metabolic process GO:0046068 16 13 0,000 5,935E-03 0,0128047 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 5,935E-03 0,0127927 ! water transport GO:0006833 17 13 0,000 5,935E-03 0,01278072 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 5,935E-03 0,01276877 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 5,935E-03 0,01275683 ! lipid localization GO:0010876 24 13 0,000 5,935E-03 0,01274492 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 5,935E-03 0,01273303 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 5,935E-03 0,01272117 ! organelle fusion GO:0048284 28 13 0,000 5,935E-03 0,01270932 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 5,935E-03 0,0126975 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 5,935E-03 0,0126857 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 5,935E-03 0,01267392 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 5,935E-03 0,01266216 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 5,935E-03 0,01265043 ! response to hexose stimulus GO:0009746 19 13 0,000 5,935E-03 0,01263872 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 5,935E-03 0,01262702 ! glutamate metabolic process GO:0006536 18 13 0,000 5,935E-03 0,01261535 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 5,935E-03 0,0126037 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 5,935E-03 0,01259208 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 5,935E-03 0,01258047 ! NAD metabolic process GO:0019674 21 13 0,000 5,935E-03 0,01256889 ! exocrine system development GO:0035272 27 13 0,000 5,935E-03 0,01255733 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 5,935E-03 0,01254578 ! bone mineralization GO:0030282 15 13 0,000 5,935E-03 0,01253426 ! regulation of exocytosis GO:0017157 17 13 0,000 5,935E-03 0,01252276 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 5,935E-03 0,01251129 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 5,935E-03 0,01249983 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 5,935E-03 0,01248839 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 5,935E-03 0,01247698 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 5,935E-03 0,01246558 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 5,935E-03 0,01245421 ! genitalia development GO:0048806 15 13 0,000 5,935E-03 0,01244286 ! regulation of cellular pH GO:0030641 20 13 0,000 5,935E-03 0,01243152 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 5,935E-03 0,01242021 ! cellular pigmentation GO:0033059 24 13 0,000 5,935E-03 0,01240892 ! tissue regeneration GO:0042246 21 13 0,000 5,935E-03 0,01239765 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 5,935E-03 0,0123864 ! cofactor transport GO:0051181 19 13 0,000 5,935E-03 0,01237517 ! NADP metabolic process GO:0006739 18 13 0,000 5,935E-03 0,01236396 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 5,935E-03 0,01235277 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 5,935E-03 0,0123416 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 5,935E-03 0,01233045 ! gas transport GO:0015669 18 13 0,000 5,935E-03 0,01231933 ! regulation of RNA stability GO:0043487 28 13 0,000 5,935E-03 0,01230822 ! heme biosynthetic process GO:0006783 20 13 0,000 5,935E-03 0,01229713 ! regulation of axon extension GO:0030516 23 13 0,000 5,935E-03 0,01228606 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 5,935E-03 0,01227501 ! lymphocyte homeostasis GO:0002260 24 13 0,000 5,935E-03 0,01226398 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 5,935E-03 0,01225297 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 5,935E-03 0,01224198 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 5,935E-03 0,01223101 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 5,935E-03 0,01222006 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 6,39E-03 0,01314567 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 6,39E-03 0,01313392 ! superoxide anion generation GO:0042554 18 14 0,000 6,39E-03 0,01312219 ! neuron maturation GO:0042551 21 14 0,000 6,39E-03 0,01311049 ! regulation of S phase GO:0033261 18 14 0,000 6,39E-03 0,0130988 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 6,39E-03 0,01308714 ! myotube differentiation GO:0014902 21 14 0,000 6,39E-03 0,01307549 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 6,39E-03 0,01306387 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 6,39E-03 0,01305227 ! heterophilic cell adhesion GO:0007157 29 14 0,000 6,39E-03 0,01304069 ! inositol metabolic process GO:0006020 20 14 0,000 6,39E-03 0,01302913 ! aminoglycan catabolic process GO:0006026 18 14 0,000 6,39E-03 0,01301759 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 6,39E-03 0,01300607 ! retina development in camera-type eye GO:0060041 18 14 0,000 6,39E-03 0,01299457 ! cardiac muscle contraction GO:0060048 23 14 0,000 6,39E-03 0,01298309 ! gene silencing by RNA GO:0031047 20 14 0,000 6,39E-03 0,01297163 ! response to cAMP GO:0051591 19 14 0,000 6,39E-03 0,01296019 ! limbic system development GO:0021761 25 14 0,000 6,39E-03 0,01294877 ! startle response GO:0001964 21 14 0,000 6,39E-03 0,01293737 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 6,39E-03 0,01292599 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 6,39E-03 0,01291464 ! activation of MAPKK activity GO:0000186 21 14 0,000 6,39E-03 0,0129033 ! regulation of defense response to virus GO:0050688 24 14 0,000 6,39E-03 0,01289198 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 6,39E-03 0,01288068 ! epidermis morphogenesis GO:0048730 29 14 0,000 6,39E-03 0,0128694 ! glycine metabolic process GO:0006544 22 14 0,000 6,39E-03 0,01285814 ! pituitary gland development GO:0021983 23 14 0,000 6,39E-03 0,0128469 ! cellular response to starvation GO:0009267 21 14 0,000 6,39E-03 0,01283568 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 6,39E-03 0,01282448 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 6,39E-03 0,0128133 ! regulation of heart rate GO:0002027 23 14 0,000 6,39E-03 0,01280214 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 6,39E-03 0,012791 ! negative regulation of caspase activity GO:0043154 20 14 0,000 6,39E-03 0,01277987 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 6,39E-03 0,01276877 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 6,39E-03 0,01275769 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 6,39E-03 0,01274662 ! G1/S transition checkpoint GO:0031575 33 14 0,000 6,39E-03 0,01273558 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 6,39E-03 0,01272455 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 6,39E-03 0,01271354 ! axon cargo transport GO:0008088 27 14 0,000 6,39E-03 0,01270255 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 6,39E-03 0,01269159 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 6,39E-03 0,01268063 ! DNA unwinding during replication GO:0006268 21 14 0,000 6,39E-03 0,0126697 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 6,39E-03 0,01265879 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 6,39E-03 0,0126479 ! mRNA splice site selection GO:0006376 26 14 0,000 6,39E-03 0,01263702 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 6,39E-03 0,01262616 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 6,39E-03 0,01261533 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 6,39E-03 0,01260451 ! sphingolipid catabolic process GO:0030149 23 14 0,000 6,39E-03 0,01259371 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 6,39E-03 0,01258292 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 6,39E-03 0,01257216 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 6,39E-03 0,01256142 ! muscle maintenance GO:0046716 19 14 0,000 6,39E-03 0,01255069 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 6,39E-03 0,01253998 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 6,39E-03 0,01252929 ! regulation of ATPase activity GO:0043462 18 14 0,000 6,39E-03 0,01251862 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 6,39E-03 0,01250796 ! cell killing GO:0001906 20 14 0,000 6,39E-03 0,01249733 ! release of cytochrome c from mitochondria GO:0001836 23 14 0,000 6,39E-03 0,01248671 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 6,39E-03 0,01247611 ! cilium assembly GO:0042384 20 14 0,000 6,39E-03 0,01246553 ! peptide hormone secretion GO:0030072 23 14 0,000 6,39E-03 0,01245496 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 6,845E-03 0,01333063 ! positive regulation of cell size GO:0045793 20 15 0,000 6,845E-03 0,01331936 ! metencephalon development GO:0022037 19 15 0,000 6,845E-03 0,0133081 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 6,845E-03 0,01329686 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 6,845E-03 0,01328564 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 6,845E-03 0,01327443 ! skin development GO:0043588 25 15 0,000 6,845E-03 0,01326325 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 6,845E-03 0,01325209 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 6,845E-03 0,01324094 ! lipid phosphorylation GO:0046834 23 15 0,000 6,845E-03 0,01322981 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 6,845E-03 0,01321871 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 6,845E-03 0,01320762 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 6,845E-03 0,01319655 ! bile acid metabolic process GO:0008206 22 15 0,000 6,845E-03 0,01318549 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 6,845E-03 0,01317446 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 6,845E-03 0,01316344 ! adult walking behavior GO:0007628 25 15 0,000 6,845E-03 0,01315245 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 6,845E-03 0,01314147 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 6,845E-03 0,01313051 ! myoblast differentiation GO:0045445 27 15 0,000 6,845E-03 0,01311957 ! centrosome cycle GO:0007098 16 15 0,000 6,845E-03 0,01310864 ! positive regulation of proteolysis GO:0045862 19 15 0,000 6,845E-03 0,01309774 ! regulation of survival gene product expression GO:0045884 20 15 0,000 6,845E-03 0,01308685 ! cardiac muscle tissue development GO:0048738 23 15 0,000 6,845E-03 0,01307598 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 6,845E-03 0,01306513 ! cerebral cortex development GO:0021987 29 15 0,000 6,845E-03 0,01305429 ! response to osmotic stress GO:0006970 22 15 0,000 6,845E-03 0,01304348 ! vesicle coating GO:0006901 25 15 0,000 6,845E-03 0,01303268 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 6,845E-03 0,0130219 ! DNA integration GO:0015074 22 15 0,000 6,845E-03 0,01301114 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 6,845E-03 0,0130004 ! peptide secretion GO:0002790 27 15 0,000 6,845E-03 0,01298967 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 6,845E-03 0,01297896 ! regulation of vasodilation GO:0042312 24 15 0,000 6,845E-03 0,01296827 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 6,845E-03 0,0129576 ! neuron recognition GO:0008038 22 15 0,000 6,845E-03 0,01294694 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 6,845E-03 0,0129363 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 6,845E-03 0,01292568 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 6,845E-03 0,01291508 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 6,845E-03 0,01290449 ! peptide biosynthetic process GO:0043043 19 15 0,000 6,845E-03 0,01289392 ! biomineral formation GO:0031214 18 15 0,000 6,845E-03 0,01288337 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 6,845E-03 0,01287284 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 6,845E-03 0,01286232 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 6,845E-03 0,01285182 ! dopamine metabolic process GO:0042417 30 15 0,000 6,845E-03 0,01284134 ! organic cation transport GO:0015695 19 15 0,000 6,845E-03 0,01283087 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 6,845E-03 0,01282042 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 6,845E-03 0,01280999 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 6,845E-03 0,01279958 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 6,845E-03 0,01278918 ! defense response to virus GO:0051607 27 15 0,000 6,845E-03 0,0127788 ! peptide hormone processing GO:0016486 19 15 0,000 6,845E-03 0,01276843 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 6,845E-03 0,01275809 ! protein secretion GO:0009306 27 16 0,000 7,3E-03 0,01359489 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 7,3E-03 0,01358389 ! hormone secretion GO:0046879 25 16 0,000 7,3E-03 0,01357291 ! bone remodeling GO:0046849 24 16 0,000 7,3E-03 0,01356194 ! endothelial cell migration GO:0043542 22 16 0,000 7,3E-03 0,013551 ! protein amino acid deacetylation GO:0006476 20 16 0,000 7,3E-03 0,01354007 ! protein amino acid acetylation GO:0006473 28 16 0,000 7,3E-03 0,01352916 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 7,3E-03 0,01351826 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 7,3E-03 0,01350739 ! glial cell development GO:0021782 24 16 0,000 7,3E-03 0,01349653 ! patterning of blood vessels GO:0001569 24 16 0,000 7,3E-03 0,01348569 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 7,3E-03 0,01347487 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 7,3E-03 0,01346406 ! protein polyubiquitination GO:0000209 26 16 0,000 7,3E-03 0,01345327 ! complement activation, alternative pathway GO:0006957 16 16 0,000 7,3E-03 0,0134425 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 7,3E-03 0,01343175 ! fructose metabolic process GO:0006000 20 16 0,000 7,3E-03 0,01342101 ! regulation of protein binding GO:0043393 27 16 0,000 7,3E-03 0,01341029 ! regulation of dephosphorylation GO:0035303 33 16 0,000 7,3E-03 0,01339959 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 7,3E-03 0,0133889 ! protein export from nucleus GO:0006611 24 16 0,000 7,3E-03 0,01337823 ! negative regulation of immune response GO:0050777 28 16 0,000 7,3E-03 0,01336758 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 7,3E-03 0,01335695 ! DNA replication initiation GO:0006270 25 16 0,000 7,3E-03 0,01334633 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 7,3E-03 0,01333573 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 7,3E-03 0,01332515 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 7,3E-03 0,01331458 ! diencephalon development GO:0021536 25 16 0,000 7,3E-03 0,01330403 ! oogenesis GO:0048477 23 16 0,000 7,3E-03 0,01329349 ! neural crest cell migration GO:0001755 24 16 0,000 7,3E-03 0,01328298 ! G1 phase GO:0051318 27 16 0,000 7,3E-03 0,01327248 ! neutrophil chemotaxis GO:0030593 21 16 0,000 7,3E-03 0,01326199 ! protein localization in mitochondrion GO:0070585 22 16 0,000 7,3E-03 0,01325153 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 7,3E-03 0,01324108 ! steroid catabolic process GO:0006706 22 16 0,000 7,3E-03 0,01323064 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 7,3E-03 0,01322022 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 7,3E-03 0,01320982 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 7,3E-03 0,01319944 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 7,3E-03 0,01318907 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 7,3E-03 0,01317872 ! sperm-egg recognition GO:0035036 16 16 0,000 7,3E-03 0,01316838 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 7,3E-03 0,01315806 ! nerve development GO:0021675 18 16 0,000 7,3E-03 0,01314776 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 7,3E-03 0,01313747 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 7,3E-03 0,0131272 ! negative regulation of translation GO:0017148 22 16 0,000 7,3E-03 0,01311694 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 7,755E-03 0,01392308 ! positive regulation of cell killing GO:0031343 24 17 0,000 7,755E-03 0,01391222 ! negative regulation of defense response GO:0031348 19 17 0,000 7,755E-03 0,01390138 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 7,755E-03 0,01389055 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 7,755E-03 0,01387974 ! glycerol metabolic process GO:0006071 20 17 0,000 7,755E-03 0,01386895 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 7,755E-03 0,01385817 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 7,755E-03 0,01384741 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 7,755E-03 0,01383667 ! signal complex assembly GO:0007172 29 17 0,000 7,755E-03 0,01382595 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 7,755E-03 0,01381524 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 7,755E-03 0,01380454 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 7,755E-03 0,01379387 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 7,755E-03 0,01378321 ! forelimb morphogenesis GO:0035136 19 17 0,000 7,755E-03 0,01377256 ! memory GO:0007613 25 17 0,000 7,755E-03 0,01376194 ! keratinization GO:0031424 17 17 0,000 7,755E-03 0,01375133 ! negative regulation of ion transport GO:0043271 20 17 0,000 7,755E-03 0,01374073 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 7,755E-03 0,01373015 ! retinoid metabolic process GO:0001523 22 17 0,000 7,755E-03 0,01371959 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 7,755E-03 0,01370905 ! inactivation of MAPK activity GO:0000188 27 17 0,000 7,755E-03 0,01369852 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 7,755E-03 0,013688 ! DNA duplex unwinding GO:0032508 25 17 0,000 7,755E-03 0,01367751 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 7,755E-03 0,01366703 ! cell-substrate junction assembly GO:0007044 39 17 0,000 7,755E-03 0,01365656 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 0,000 7,755E-03 0,01364611 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 7,755E-03 0,01363568 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 7,755E-03 0,01362526 ! membrane budding GO:0006900 29 17 0,000 7,755E-03 0,01361486 ! heme metabolic process GO:0042168 27 17 0,000 7,755E-03 0,01360448 ! actin filament bundle formation GO:0051017 26 17 0,000 7,755E-03 0,01359411 ! neuromuscular junction development GO:0007528 23 17 0,000 7,755E-03 0,01358375 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 7,755E-03 0,01357342 ! body fluid secretion GO:0007589 27 17 0,000 7,755E-03 0,01356309 ! stem cell differentiation GO:0048863 36 17 0,000 7,755E-03 0,01355279 ! nucleobase metabolic process GO:0009112 31 17 0,000 7,755E-03 0,0135425 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 7,755E-03 0,01353222 ! behavioral interaction between organisms GO:0051705 25 17 0,000 7,755E-03 0,01352196 ! sensory perception of pain GO:0019233 23 17 0,000 7,755E-03 0,01351172 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 7,755E-03 0,01350149 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 7,755E-03 0,01349128 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 7,755E-03 0,01348108 ! synaptogenesis GO:0007416 24 17 0,000 7,755E-03 0,0134709 ! peptidyl-serine modification GO:0018209 27 17 0,000 7,755E-03 0,01346073 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 7,755E-03 0,01345058 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 7,755E-03 0,01344044 ! cell-cell junction organization GO:0045216 25 17 0,000 7,755E-03 0,01343032 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 7,755E-03 0,01342022 ! proximal/distal pattern formation GO:0009954 25 17 0,000 7,755E-03 0,01341013 ! aromatic compound catabolic process GO:0019439 22 17 0,000 7,755E-03 0,01340005 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 7,755E-03 0,01338999 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 7,755E-03 0,01337995 ! negative regulation of coagulation GO:0050819 23 17 0,000 7,755E-03 0,01336992 ! positive regulation of DNA replication GO:0045740 29 18 0,000 8,209E-03 0,01414295 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 8,209E-03 0,01413236 ! positive regulation of translation GO:0045727 28 18 0,000 8,209E-03 0,01412179 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 8,209E-03 0,01411124 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 8,209E-03 0,0141007 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 8,209E-03 0,01409018 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 8,209E-03 0,01407967 ! cAMP metabolic process GO:0046058 33 18 0,000 8,209E-03 0,01406918 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 8,209E-03 0,0140587 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 8,209E-03 0,01404824 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 8,209E-03 0,0140378 ! axis specification GO:0009798 26 18 0,000 8,209E-03 0,01402737 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 8,209E-03 0,01401695 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 8,209E-03 0,01400655 ! pancreas development GO:0031016 26 18 0,000 8,209E-03 0,01399617 ! apoptotic mitochondrial changes GO:0008637 29 18 0,000 8,209E-03 0,0139858 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 8,209E-03 0,01397545 ! glutamine metabolic process GO:0006541 23 18 0,000 8,209E-03 0,01396511 ! response to retinoic acid GO:0032526 25 18 0,000 8,209E-03 0,01395479 ! pigmentation during development GO:0048066 31 18 0,000 8,209E-03 0,01394449 ! central nervous system neuron development GO:0021954 30 18 0,000 8,209E-03 0,0139342 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 8,209E-03 0,01392392 ! fucose metabolic process GO:0006004 26 18 0,000 8,209E-03 0,01391366 ! response to fungus GO:0009620 19 18 0,000 8,209E-03 0,01390341 ! peptide cross-linking GO:0018149 31 18 0,000 8,209E-03 0,01389318 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 8,209E-03 0,01388297 ! heart process GO:0003015 27 18 0,000 8,209E-03 0,01387277 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 8,209E-03 0,01386258 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 8,209E-03 0,01385241 ! visual learning GO:0008542 35 18 0,000 8,209E-03 0,01384225 ! somitogenesis GO:0001756 24 18 0,000 8,209E-03 0,01383211 ! synaptic vesicle transport GO:0048489 33 18 0,000 8,209E-03 0,01382199 ! detection of chemical stimulus GO:0009593 26 18 0,000 8,209E-03 0,01381188 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 8,209E-03 0,01380178 ! cellular response to nutrient levels GO:0031669 27 18 0,000 8,209E-03 0,0137917 ! regulation of cytokine secretion GO:0050707 26 18 0,000 8,209E-03 0,01378163 ! vitamin transport GO:0051180 24 18 0,000 8,209E-03 0,01377158 ! hormone transport GO:0009914 27 18 0,000 8,209E-03 0,01376154 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 8,209E-03 0,01375152 ! activation of JUN kinase activity GO:0007257 23 18 0,000 8,209E-03 0,01374151 ! terpenoid metabolic process GO:0006721 24 18 0,000 8,209E-03 0,01373152 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 8,209E-03 0,01372154 ! cell-cell recognition GO:0009988 20 18 0,000 8,209E-03 0,01371157 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 8,209E-03 0,01370162 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 8,209E-03 0,01369169 ! regulation of glucose import GO:0046324 21 18 0,000 8,209E-03 0,01368176 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 8,209E-03 0,01367186 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 8,209E-03 0,01366196 ! negative regulation of T cell activation GO:0050868 25 18 0,000 8,209E-03 0,01365209 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 8,209E-03 0,01364222 ! protein import into nucleus, docking GO:0000059 30 19 0,000 8,663E-03 0,01438685 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 8,663E-03 0,01437647 ! positive regulation of fibroblast proliferation GO:0048146 27 19 0,000 8,663E-03 0,0143661 ! positive regulation of ossification GO:0045778 30 19 0,000 8,663E-03 0,01435575 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 8,663E-03 0,01434542 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 8,663E-03 0,01433509 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 8,663E-03 0,01432479 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 8,663E-03 0,0143145 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 8,663E-03 0,01430422 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 8,663E-03 0,01429396 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 8,663E-03 0,01428371 ! regeneration GO:0031099 32 19 0,000 8,663E-03 0,01427348 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 8,663E-03 0,01426327 ! response to alkaloid GO:0043279 32 19 0,000 8,663E-03 0,01425306 ! sensory perception of taste GO:0050909 23 19 0,000 8,663E-03 0,01424287 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 8,663E-03 0,0142327 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 0,000 8,663E-03 0,01422254 ! smooth muscle contraction GO:0006939 36 19 0,000 8,663E-03 0,0142124 ! peroxisome organization GO:0007031 29 19 0,000 8,663E-03 0,01420227 ! digestive system process GO:0022600 30 19 0,000 8,663E-03 0,01419215 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 8,663E-03 0,01418205 ! polysaccharide catabolic process GO:0000272 23 19 0,000 8,663E-03 0,01417196 ! response to vitamin A GO:0033189 26 19 0,000 8,663E-03 0,01416189 ! D-ribose metabolic process GO:0006014 25 19 0,000 8,663E-03 0,01415183 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 8,663E-03 0,01414179 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 8,663E-03 0,01413176 ! apoptotic nuclear changes GO:0030262 24 19 0,000 8,663E-03 0,01412174 ! response to starvation GO:0042594 30 19 0,000 8,663E-03 0,01411174 ! sex determination GO:0007530 29 19 0,000 8,663E-03 0,01410176 ! response to lipopolysaccharide GO:0032496 26 19 0,000 8,663E-03 0,01409178 ! plasma membrane fusion GO:0045026 23 19 0,000 8,663E-03 0,01408182 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 8,663E-03 0,01407188 ! cytolysis GO:0019835 20 19 0,000 8,663E-03 0,01406195 ! renal system process GO:0003014 35 19 0,000 8,663E-03 0,01405203 ! vasodilation GO:0042311 33 19 0,000 8,663E-03 0,01404213 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 8,663E-03 0,01403224 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 8,663E-03 0,01402237 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 8,663E-03 0,0140125 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 8,663E-03 0,01400266 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 8,663E-03 0,01399282 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 8,663E-03 0,013983 ! positive regulation of neurological system process GO:0031646 28 19 0,000 8,663E-03 0,0139732 ! sarcomere organization GO:0045214 23 19 0,000 8,663E-03 0,01396341 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 8,663E-03 0,01395363 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 8,663E-03 0,01394386 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 8,663E-03 0,01393411 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 8,663E-03 0,01392438 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 8,663E-03 0,01391465 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 8,663E-03 0,01390494 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 8,663E-03 0,01389525 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 8,663E-03 0,01388556 ! protein stabilization GO:0050821 26 19 0,000 8,663E-03 0,01387589 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 9,118E-03 0,01459312 ! iron ion transport GO:0006826 37 20 0,000 9,118E-03 0,01458297 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 9,118E-03 0,01457284 ! glucosamine metabolic process GO:0006041 25 20 0,000 9,118E-03 0,01456272 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 9,118E-03 0,01455261 ! response to vitamin GO:0033273 29 20 0,000 9,118E-03 0,01454252 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 9,118E-03 0,01453244 ! hindlimb morphogenesis GO:0035137 32 20 0,000 9,118E-03 0,01452238 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 9,118E-03 0,01451233 ! spinal cord development GO:0021510 31 20 0,000 9,118E-03 0,01450229 ! response to ethanol GO:0045471 37 20 0,000 9,118E-03 0,01449227 ! multicellular organismal response to stress GO:0033555 32 20 0,000 9,118E-03 0,01448226 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 0,000 9,118E-03 0,01447226 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 9,118E-03 0,01446228 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 9,118E-03 0,01445232 ! chromosome condensation GO:0030261 31 20 0,000 9,118E-03 0,01444236 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 9,118E-03 0,01443242 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 9,118E-03 0,0144225 ! determination of left/right symmetry GO:0007368 23 20 0,000 9,118E-03 0,01441258 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 9,118E-03 0,01440269 ! pallium development GO:0021543 38 20 0,000 9,118E-03 0,0143928 ! DNA modification GO:0006304 28 20 0,000 9,118E-03 0,01438293 ! positive regulation of locomotion GO:0040017 35 20 0,000 9,118E-03 0,01437307 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 9,118E-03 0,01436323 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 9,118E-03 0,01435339 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 9,118E-03 0,01434358 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 9,118E-03 0,01433377 ! positive regulation of B cell activation GO:0050871 31 20 0,000 9,118E-03 0,01432398 ! collagen catabolic process GO:0030574 25 20 0,000 9,118E-03 0,0143142 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 9,118E-03 0,01430444 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 9,118E-03 0,01429469 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 9,118E-03 0,01428495 ! alditol metabolic process GO:0019400 24 20 0,000 9,118E-03 0,01427523 ! actin filament-based movement GO:0030048 34 20 0,000 9,118E-03 0,01426552 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 9,571E-03 0,01496561 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 9,571E-03 0,01495545 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 9,571E-03 0,01494529 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 9,571E-03 0,01493516 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 9,571E-03 0,01492503 ! determination of bilateral symmetry GO:0009855 25 21 0,000 9,571E-03 0,01491492 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 9,571E-03 0,01490482 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 9,571E-03 0,01489474 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 9,571E-03 0,01488466 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 9,571E-03 0,01487461 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 9,571E-03 0,01486456 ! protein amino acid acylation GO:0043543 37 21 0,000 9,571E-03 0,01485453 ! regulation of chemotaxis GO:0050920 36 21 0,000 9,571E-03 0,01484452 ! vesicle docking GO:0048278 27 21 0,000 9,571E-03 0,01483451 ! phototransduction GO:0007602 25 21 0,000 9,571E-03 0,01482452 ! dendrite development GO:0016358 35 21 0,000 9,571E-03 0,01481455 ! visual behavior GO:0007632 39 21 0,000 9,571E-03 0,01480459 ! regulation of DNA recombination GO:0000018 40 21 0,000 9,571E-03 0,01479464 ! ovarian follicle development GO:0001541 30 21 0,000 9,571E-03 0,0147847 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 9,571E-03 0,01477478 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 9,571E-03 0,01476487 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 9,571E-03 0,01475497 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 9,571E-03 0,01474509 ! cell aging GO:0007569 32 21 0,000 9,571E-03 0,01473522 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 9,571E-03 0,01472536 ! regulation of insulin secretion GO:0050796 26 21 0,000 9,571E-03 0,01471552 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 9,571E-03 0,01470569 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 9,571E-03 0,01469587 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 9,571E-03 0,01468607 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 9,571E-03 0,01467628 ! leukotriene metabolic process GO:0006691 28 21 0,000 9,571E-03 0,0146665 ! regulation of vasoconstriction GO:0019229 31 21 0,000 9,571E-03 0,01465674 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 9,571E-03 0,01464699 ! fatty acid transport GO:0015908 30 21 0,000 9,571E-03 0,01463725 ! immunoglobulin production GO:0002377 33 21 0,000 9,571E-03 0,01462752 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 9,571E-03 0,01461781 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 9,571E-03 0,01460811 ! positive regulation of protein secretion GO:0050714 26 21 0,000 9,571E-03 0,01459842 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 9,571E-03 0,01458875 ! cellular response to extracellular stimulus GO:0031668 32 21 0,000 9,571E-03 0,01457909 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 9,571E-03 0,01456944 ! regulation of bone mineralization GO:0030500 29 21 0,000 9,571E-03 0,0145598 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 9,571E-03 0,01455018 ! response to cytokine stimulus GO:0034097 47 21 0,000 9,571E-03 0,01454057 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 9,571E-03 0,01453097 ! porphyrin metabolic process GO:0006778 35 21 0,000 9,571E-03 0,01452138 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 9,571E-03 0,01451181 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 9,571E-03 0,01450225 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 9,571E-03 0,01449271 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 9,571E-03 0,01448317 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,01002527 0,01515984 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,01002527 0,01514988 ! regulation of fibroblast proliferation GO:0048145 35 22 0,000 0,01002527 0,01513993 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,01002527 0,01512999 ! viral genome replication GO:0019079 29 22 0,000 0,01002527 0,01512007 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,01002527 0,01511016 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,01002527 0,01510027 ! leukocyte adhesion GO:0007159 38 22 0,000 0,01002527 0,01509039 ! molting cycle process GO:0022404 40 22 0,000 0,01002527 0,01508052 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,01002527 0,01507066 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,01002527 0,01506082 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,01002527 0,01505099 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,01002527 0,01504117 ! vasculogenesis GO:0001570 33 22 0,000 0,01002527 0,01503136 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,01002527 0,01502157 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,01002527 0,01501179 GO:0010810|regulation of cell-substrate adhesion, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,01002527 0,01500202 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,01002527 0,01499227 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,01002527 0,01498253 ! lysosome organization GO:0007040 37 22 0,000 0,01002527 0,0149728 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,01002527 0,01496308 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,01002527 0,01495338 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,01002527 0,01494369 ! regulation of behavior GO:0050795 38 22 0,000 0,01002527 0,01493401 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,01002527 0,01492434 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,01002527 0,01491469 ! membrane depolarization GO:0051899 35 22 0,000 0,01002527 0,01490505 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,01002527 0,01489542 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,01002527 0,0148858 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,01002527 0,0148762 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,01002527 0,01486661 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,01002527 0,01485703 ! blastocyst development GO:0001824 37 22 0,000 0,01002527 0,01484746 ! neural tube closure GO:0001843 33 22 0,000 0,01002527 0,01483791 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,01002527 0,01482837 ! protein tetramerization GO:0051262 39 22 0,000 0,01002527 0,01481884 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,01047886 0,01547937 ! neuron fate commitment GO:0048663 32 23 0,000 0,01047886 0,01546944 ! embryonic pattern specification GO:0009880 31 23 0,000 0,01047886 0,01545951 ! positive regulation of cell adhesion GO:0045785 37 23 0,000 0,01047886 0,0154496 ! myelination GO:0042552 35 23 0,000 0,01047886 0,01543971 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,01047886 0,01542982 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,01047886 0,01541995 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,01047886 0,01541009 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,01047886 0,01540024 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,01047886 0,01539041 ! vesicle targeting GO:0006903 32 23 0,000 0,01047886 0,01538059 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,01047886 0,01537078 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,01047886 0,01536098 ! osteoblast differentiation GO:0001649 40 23 0,000 0,01047886 0,0153512 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,01047886 0,01534143 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,01047886 0,01533167 ! interaction with host GO:0051701 37 23 0,000 0,01047886 0,01532192 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,01047886 0,01531219 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,01047886 0,01530247 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,01047886 0,01529276 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,01047886 0,01528306 ! negative regulation of phosphorylation GO:0042326 41 23 0,000 0,01047886 0,01527337 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,01047886 0,0152637 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,01047886 0,01525404 ! cell fate determination GO:0001709 45 23 0,000 0,01047886 0,01524439 ! pentose metabolic process GO:0019321 31 23 0,000 0,01047886 0,01523476 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,01047886 0,01522513 ! spermatid development GO:0007286 33 23 0,000 0,01047886 0,01521552 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,01047886 0,01520592 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,01047886 0,01519633 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,01047886 0,01518676 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,01047886 0,01517719 ! telomere organization GO:0032200 32 23 0,000 0,01047886 0,01516764 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,01047886 0,0151581 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,01047886 0,01514857 ! regulation of amine transport GO:0051952 38 23 0,000 0,01047886 0,01513906 ! liver development GO:0001889 40 23 0,000 0,01047886 0,01512956 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,01093228 0,0157743 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,01093228 0,01576441 ! initiation of viral infection GO:0019059 42 24 0,000 0,01093228 0,01575453 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,01093228 0,01574467 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,01093228 0,01573482 ! superoxide metabolic process GO:0006801 32 24 0,000 0,01093228 0,01572498 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,01093228 0,01571515 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! insulin receptor signaling pathway GO:0008286 40 24 0,000 0,01093228 0,01570533 ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,01093228 0,01569553 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,01093228 0,01568574 ! sperm motility GO:0030317 27 24 0,000 0,01093228 0,01567596 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,01093228 0,01566619 ! vacuole organization GO:0007033 39 24 0,000 0,01093228 0,01565644 ! receptor metabolic process GO:0043112 37 24 0,000 0,01093228 0,01564669 ! neural crest cell development GO:0014032 39 24 0,000 0,01093228 0,01563696 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,01093228 0,01562724 ! primary neural tube formation GO:0014020 35 24 0,000 0,01093228 0,01561754 ! negative regulation of cell development GO:0010721 56 24 0,000 0,01093228 0,01560784 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,01093228 0,01559816 ! base-excision repair GO:0006284 31 24 0,000 0,01093228 0,01558849 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,01093228 0,01557883 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,01093228 0,01556919 ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,01093228 0,01555955 ! glutathione metabolic process GO:0006749 29 24 0,000 0,01093228 0,01554993 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,01093228 0,01554032 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,01093228 0,01553072 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,01093228 0,01552113 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,01138551 0,01615464 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,01138551 0,01614468 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,01138551 0,01613473 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,01138551 0,0161248 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,01138551 0,01611488 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,01138551 0,01610496 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 0,000 0,01138551 0,01609507 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,01138551 0,01608518 ! peptide transport GO:0015833 43 25 0,000 0,01138551 0,01607531 ! male gonad development GO:0008584 33 25 0,000 0,01138551 0,01606544 ! iron ion homeostasis GO:0055072 39 25 0,000 0,01138551 0,01605559 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,01138551 0,01604576 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,01138551 0,01603593 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,01138551 0,01602612 ! phospholipid transport GO:0015914 35 25 0,000 0,01138551 0,01601631 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,01138551 0,01600652 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,01138551 0,01599675 ! detection of light stimulus GO:0009583 30 25 0,000 0,01138551 0,01598698 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,01138551 0,01597723 GO:0045840|positive regulation of mitosis, ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,01138551 0,01596748 ! leukocyte proliferation GO:0070661 39 25 0,000 0,01138551 0,01595775 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,01138551 0,01594803 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,01183856 0,01657254 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,01183856 0,01656246 ! translational initiation GO:0006413 43 26 0,000 0,01183856 0,0165524 ! regulation of pH GO:0006885 36 26 0,000 0,01183856 0,01654234 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 0,000 0,01183856 0,0165323 ! circadian rhythm GO:0007623 42 26 0,000 0,01183856 0,01652226 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,01183856 0,01651224 ! post-embryonic development GO:0009791 42 26 0,000 0,01183856 0,01650224 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,01183856 0,01649224 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,01183856 0,01648226 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,01183856 0,01647229 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,01183856 0,01646233 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,01183856 0,01645238 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,01183856 0,01644245 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,01183856 0,01643252 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,01183856 0,01642261 ! regulation of coagulation GO:0050818 39 26 0,000 0,01183856 0,01641271 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,01229143 0,0170303 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,01229143 0,01702004 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,01229143 0,0170098 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,01229143 0,01699957 ! membrane docking GO:0022406 39 27 0,000 0,01229143 0,01698936 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,01229143 0,01697915 ! catechol metabolic process GO:0009712 43 27 0,000 0,01229143 0,01696896 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,01229143 0,01695878 ! acute-phase response GO:0006953 42 27 0,000 0,01229143 0,01694862 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,01229143 0,01693846 ! myofibril assembly GO:0030239 36 27 0,000 0,01229143 0,01692832 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,01229143 0,01691819 ! response to ionizing radiation GO:0010212 47 27 0,000 0,01229143 0,01690807 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,01229143 0,01689796 ! natural killer cell activation GO:0030101 35 27 0,000 0,01229143 0,01688787 ! lipid oxidation GO:0034440 38 27 0,000 0,01229143 0,01687779 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,01229143 0,01686772 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,01229143 0,01685766 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,01229143 0,01684761 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,01229143 0,01683758 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,01229143 0,01682755 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,01229143 0,01681754 ! gene silencing GO:0016458 41 27 0,000 0,01229143 0,01680754 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,01274412 0,0174162 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,01274412 0,01740586 ! phenol metabolic process GO:0018958 44 28 0,000 0,01274412 0,01739553 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,01274412 0,01738522 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,01274412 0,01737491 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,01274412 0,01736462 ! cell junction assembly GO:0034329 56 28 0,000 0,01274412 0,01735434 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,01274412 0,01734407 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,01274412 0,01733381 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,01274412 0,01732357 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,01274412 0,01731333 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,01274412 0,01730311 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,01274412 0,0172929 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,01274412 0,01728271 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,01274412 0,01727252 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,01274412 0,01726235 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,01274412 0,01725219 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,01274412 0,01724204 ! mesoderm formation GO:0001707 46 28 0,000 0,01274412 0,01723191 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,01274412 0,01722178 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,01274412 0,01721167 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,01274412 0,01720157 ! ensheathment of neurons GO:0007272 43 28 0,000 0,01274412 0,01719148 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,01274412 0,0171814 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,01274412 0,01717134 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,01274412 0,01716128 ! neural tube formation GO:0001841 41 28 0,000 0,01274412 0,01715124 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,01274412 0,01714121 ! placenta development GO:0001890 37 28 0,000 0,01274412 0,01713119 ! regulation of B cell activation GO:0050864 42 28 0,000 0,01274412 0,01712119 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,01319663 0,01771876 ! regulation of innate immune response GO:0045088 38 29 0,000 0,01319663 0,01770842 ! ovulation cycle process GO:0022602 41 29 0,000 0,01319663 0,0176981 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,01319663 0,01768778 ! protein targeting to membrane GO:0006612 53 29 0,000 0,01319663 0,01767748 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,01319663 0,01766719 ! mismatch repair GO:0006298 34 29 0,000 0,01319663 0,01765692 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,01319663 0,01764665 ! muscle cell development GO:0055001 38 29 0,000 0,01319663 0,0176364 ! formation of primary germ layer GO:0001704 48 29 0,000 0,01319663 0,01762615 ! telencephalon development GO:0021537 52 29 0,000 0,01319663 0,01761592 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,01319663 0,01760571 ! eye morphogenesis GO:0048592 51 29 0,000 0,01319663 0,0175955 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,01319663 0,01758531 ! tissue homeostasis GO:0001894 42 29 0,000 0,01319663 0,01757512 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,01364895 0,01816701 ! collagen metabolic process GO:0032963 40 30 0,000 0,01364895 0,0181565 ! organic anion transport GO:0015711 51 30 0,000 0,01364895 0,018146 ! cholesterol transport GO:0030301 46 30 0,000 0,01364895 0,01813552 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,01364895 0,01812505 ! spliceosome assembly GO:0000245 49 30 0,000 0,01364895 0,01811459 ! spindle organization GO:0007051 37 30 0,000 0,01364895 0,01810414 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,01364895 0,01809371 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,01364895 0,01808329 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,01364895 0,01807288 ! ceramide metabolic process GO:0006672 43 30 0,000 0,01364895 0,01806248 ! ovulation cycle GO:0042698 43 30 0,000 0,01364895 0,01805209 ! hindbrain development GO:0030902 45 30 0,000 0,01364895 0,01804172 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,01364895 0,01803135 ! adult locomotory behavior GO:0008344 47 30 0,000 0,01364895 0,018021 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,01364895 0,01801066 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,01364895 0,01800034 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,01364895 0,01799002 ! response to heat GO:0009408 41 30 0,000 0,01364895 0,01797972 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,01364895 0,01796942 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,01364895 0,01795914 ! negative regulation of secretion GO:0051048 49 31 0,000 0,01410109 0,01854346 ! mammary gland development GO:0030879 57 31 0,000 0,01410109 0,01853287 ! glial cell differentiation GO:0010001 55 31 0,000 0,01410109 0,01852228 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,01410109 0,01851171 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,01410109 0,01850115 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,01410109 0,0184906 ! odontogenesis GO:0042476 50 31 0,000 0,01410109 0,01848007 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,01410109 0,01846954 ! segmentation GO:0035282 41 31 0,000 0,01410109 0,01845903 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,01410109 0,01844853 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,01410109 0,01843804 ! metanephros development GO:0001656 58 31 0,000 0,01410109 0,01842757 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,01410109 0,0184171 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,01410109 0,01840665 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,01410109 0,01839621 ! cell fate specification GO:0001708 37 31 0,000 0,01410109 0,01838578 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,01410109 0,01837536 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,01410109 0,01836496 ! RNA modification GO:0009451 40 31 0,000 0,01410109 0,01835456 ! regulation of muscle development GO:0048634 48 32 0,000 0,01455306 0,01893214 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,01455306 0,01892144 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,01455306 0,01891075 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,01455306 0,01890007 ! meiosis I GO:0007127 52 32 0,000 0,01455306 0,01888941 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,01455306 0,01887875 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,01455306 0,01886811 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,01455306 0,01885748 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,01455306 0,01884686 ! peripheral nervous system development GO:0007422 53 32 0,000 0,01455306 0,01883626 ! regulation of protein stability GO:0031647 48 32 0,000 0,01455306 0,01882566 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,01455306 0,01881508 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,01455306 0,01880451 ! cytokine production GO:0001816 44 32 0,000 0,01455306 0,01879395 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,01455306 0,01878341 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,01455306 0,01877287 ! vesicle localization GO:0051648 47 32 0,000 0,01455306 0,01876235 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,01500484 0,01933396 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,01500484 0,01932314 ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,01500484 0,01931232 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,01500484 0,01930152 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,01500484 0,01929073 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,01500484 0,01927996 ! sister chromatid segregation GO:0000819 46 33 0,000 0,01500484 0,01926919 ! ear morphogenesis GO:0042471 42 33 0,000 0,01500484 0,01925844 ! actomyosin structure organization GO:0031032 43 33 0,000 0,01500484 0,0192477 ! cell junction organization GO:0034330 63 33 0,000 0,01500484 0,01923697 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,01500484 0,01922625 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,01500484 0,01921555 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,01500484 0,01920485 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 0,000 0,01500484 0,01919417 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,01500484 0,0191835 ! female gonad development GO:0008585 49 33 0,000 0,01500484 0,01917285 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,01500484 0,0191622 ! positive regulation of cell development GO:0010720 54 33 0,000 0,01500484 0,01915157 ! lipid homeostasis GO:0055088 55 33 0,000 0,01500484 0,01914094 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,01500484 0,01913033 ! regulation of proteolysis GO:0030162 50 33 0,000 0,01500484 0,01911974 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,01500484 0,01910915 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,01500484 0,01909857 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,01500484 0,01908801 ! cytokinesis GO:0000910 52 33 0,000 0,01500484 0,01907746 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,01500484 0,01906692 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,01545644 0,01962993 ! mRNA catabolic process GO:0006402 48 34 0,000 0,01545644 0,0196191 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,01545644 0,01960828 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,01545644 0,01959747 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,01545644 0,01958667 ! feeding behavior GO:0007631 45 34 0,000 0,01545644 0,01957588 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,01545644 0,01956511 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,01545644 0,01955435 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,01545644 0,0195436 ! neuron migration GO:0001764 46 34 0,000 0,01545644 0,01953286 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,01545644 0,01952213 ! female gamete generation GO:0007292 43 34 0,000 0,01545644 0,01951142 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,01545644 0,01950071 ! polyol metabolic process GO:0019751 44 34 0,000 0,01545644 0,01949002 ! aerobic respiration GO:0009060 47 34 0,000 0,01545644 0,01947934 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,01545644 0,01946868 ! cellular response to insulin stimulus GO:0032869 52 34 0,000 0,01545644 0,01945802 ! embryonic organ development GO:0048568 45 34 0,000 0,01545644 0,01944738 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,01545644 0,01943674 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,01590785 0,01999348 ! Notch signaling pathway GO:0007219 56 35 0,000 0,01590785 0,01998256 ! regulation of intracellular protein transport GO:0033157 59 35 0,000 0,01590785 0,01997165 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,01590785 0,01996076 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,01590785 0,01994987 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,01590785 0,019939 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,01590785 0,01992814 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,01590785 0,01991729 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,01590785 0,01990646 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,01590785 0,01989563 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,01590785 0,01988482 ! glycogen metabolic process GO:0005977 48 35 0,000 0,01590785 0,01987402 ! pigment metabolic process GO:0042440 61 35 0,000 0,01590785 0,01986323 ! positive regulation of leukocyte proliferation GO:0070665 50 35 0,000 0,01590785 0,01985245 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! protein homooligomerization GO:0051260 52 35 0,000 0,01590785 0,01984168 ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,01635909 0,02039345 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 0,000 0,01635909 0,0203824 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,01635909 0,02037136 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,01635909 0,02036034 ! negative regulation of binding GO:0051100 58 36 0,000 0,01635909 0,02034933 ! organic ether metabolic process GO:0018904 46 36 0,000 0,01635909 0,02033833 ! tissue remodeling GO:0048771 62 36 0,000 0,01635909 0,02032734 ! neural tube development GO:0021915 50 36 0,000 0,01635909 0,02031637 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,01635909 0,0203054 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,01635909 0,02029445 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,01635909 0,02028351 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,01635909 0,02027258 ! glucan metabolic process GO:0044042 49 36 0,000 0,01635909 0,02026166 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,01681015 0,02080912 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,01681015 0,02079792 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,01681015 0,02078674 ! learning GO:0007612 67 37 0,000 0,01681015 0,02077557 ! ion transmembrane transport GO:0034220 56 37 0,000 0,01681015 0,02076441 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,01681015 0,02075327 ! regulation of protein secretion GO:0050708 51 37 0,000 0,01681015 0,02074214 ! amino acid activation GO:0043038 52 37 0,000 0,01681015 0,02073101 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,01681015 0,0207199 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,01726102 0,02126425 ! gliogenesis GO:0042063 71 38 0,000 0,01726102 0,02125287 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,01726102 0,02124149 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,01726102 0,02123014 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,01726102 0,02121879 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,01726102 0,02120745 ! phagocytosis GO:0006909 60 38 0,000 0,01726102 0,02119613 ! mesenchymal cell development GO:0014031 64 38 0,000 0,01726102 0,02118482 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 0,000 0,01726102 0,02117352 ! maintenance of location in cell GO:0051651 69 38 0,000 0,01726102 0,02116224 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,01771172 0,02170322 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,01771172 0,02169167 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,01771172 0,02168012 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,01771172 0,02166859 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,01771172 0,02165707 ! regulation of epithelial cell proliferation GO:0050678 71 39 0,000 0,01771172 0,02164556 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,01771172 0,02163407 ! male sex differentiation GO:0046661 53 39 0,000 0,01771172 0,02162259 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,01771172 0,02161111 ! chromatin remodeling GO:0006338 68 39 0,000 0,01771172 0,02159966 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,01771172 0,02158821 ! JNK cascade GO:0007254 54 39 0,000 0,01771172 0,02157677 ! developmental growth GO:0048589 62 39 0,000 0,01771172 0,02156535 ! cell growth GO:0016049 61 39 0,000 0,01771172 0,02155394 ! synapse organization GO:0050808 55 39 0,000 0,01771172 0,02154254 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,01816223 0,02207882 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,01816223 0,02206716 ! regulation of tube size GO:0035150 60 40 0,000 0,01816223 0,02205551 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,01816223 0,02204387 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,01816223 0,02203224 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,01816223 0,02202063 ! peptide metabolic process GO:0006518 56 40 0,000 0,01816223 0,02200903 ! induction of apoptosis by intracellular signals GO:0008629 67 40 0,000 0,01816223 0,02199744 ! inner ear development GO:0048839 57 40 0,000 0,01816223 0,02198586 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,01816223 0,02197429 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,01816223 0,02196274 ! double-strand break repair GO:0006302 67 40 0,000 0,01816223 0,0219512 ! B cell differentiation GO:0030183 62 40 0,000 0,01816223 0,02193967 ! epidermal cell differentiation GO:0009913 53 40 0,000 0,01816223 0,02192815 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,01816223 0,02191665 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,01816223 0,02190516 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,01816223 0,02189367 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,01861256 0,02242478 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,01861256 0,02241303 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,01861256 0,02240131 ! glucose transport GO:0015758 52 41 0,000 0,01861256 0,02238959 ! endosome transport GO:0016197 71 41 0,000 0,01861256 0,02237789 ! striated muscle contraction GO:0006941 62 41 0,000 0,01861256 0,02236619 ! positive regulation of DNA binding GO:0043388 57 41 0,000 0,01861256 0,02235452 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,01861256 0,02234285 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,01861256 0,02233119 ! biopolymer methylation GO:0043414 62 41 0,000 0,01861256 0,02231955 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,01861256 0,02230792 ! mitochondrial transport GO:0006839 60 42 0,000 0,01906272 0,02283554 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,01906272 0,02282366 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 0,000 0,01906272 0,02281178 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,01906272 0,02279992 ! cellular component disassembly GO:0022411 64 42 0,000 0,01906272 0,02278807 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,01906272 0,02277623 ! hexose transport GO:0008645 54 42 0,000 0,01906272 0,02276441 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,01906272 0,02275259 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,01906272 0,02274079 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,01906272 0,022729 ! excretion GO:0007588 63 42 0,000 0,01906272 0,02271723 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,01906272 0,02270546 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,01906272 0,02269371 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,01906272 0,02268197 ! regulation of cell shape GO:0008360 78 42 0,000 0,01906272 0,02267024 ! positive regulation of binding GO:0051099 59 43 0,000 0,01951269 0,02319337 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,01951269 0,02318139 ! leukocyte migration GO:0050900 60 43 0,000 0,01951269 0,02316943 ! neuromuscular process GO:0050905 79 43 0,000 0,01951269 0,02315747 ! activation of caspase activity GO:0006919 65 43 0,000 0,01951269 0,02314553 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,01951269 0,0231336 ! tRNA processing GO:0008033 49 43 0,000 0,01951269 0,02312168 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,01951269 0,02310977 ! vesicle organization GO:0016050 79 43 0,000 0,01951269 0,02309788 ! response to insulin stimulus GO:0032868 63 43 0,000 0,01951269 0,023086 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,01951269 0,02307413 ! methylation GO:0032259 64 43 0,000 0,01951269 0,02306227 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,01996248 0,02358177 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,01996248 0,02356966 ! glycolysis GO:0006096 53 44 0,000 0,01996248 0,02355757 ! regulation of action potential GO:0001508 71 44 0,000 0,01996248 0,02354549 ! regulation of ion transport GO:0043269 57 44 0,000 0,01996248 0,02353342 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,01996248 0,02352136 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,01996248 0,02350932 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,01996248 0,02349729 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,01996248 0,02348527 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,01996248 0,02347326 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,01996248 0,02346127 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,01996248 0,02344928 ! regulation of mast cell proliferation GO:0070666 64 44 0,000 0,01996248 0,02343731 ! RNA catabolic process GO:0006401 64 45 0,000 0,02041209 0,02395296 ! positive regulation of defense response GO:0031349 59 45 0,000 0,02041209 0,02394075 ! regulation of translational initiation GO:0006446 64 45 0,000 0,02041209 0,02392854 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,02041209 0,02391635 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,02041209 0,02390418 ! cell recognition GO:0008037 58 45 0,000 0,02041209 0,02389201 ! cell maturation GO:0048469 60 45 0,000 0,02041209 0,02387986 ! protein amino acid autophosphorylation GO:0046777 80 45 0,000 0,02041209 0,02386772 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,02086152 0,02438084 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,02086152 0,02436846 ! cell redox homeostasis GO:0045454 63 46 0,000 0,02086152 0,02435609 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,02086152 0,02434373 ! regulation of ossification GO:0030278 71 46 0,000 0,02086152 0,02433138 ! histone modification GO:0016570 68 46 0,000 0,02086152 0,02431905 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,02086152 0,02430673 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,02131077 0,0248176 ! viral infectious cycle GO:0019058 71 47 0,000 0,02131077 0,02480504 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,02131077 0,02479249 ! endocrine system development GO:0035270 83 47 0,000 0,02131077 0,02477996 ! covalent chromatin modification GO:0016569 75 47 0,000 0,02131077 0,02476744 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,02131077 0,02475493 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,02131077 0,02474243 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,02131077 0,02472995 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,02131077 0,02471748 ! regulation of leukocyte proliferation GO:0070663 71 47 0,000 0,02131077 0,02470502 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,02131077 0,02469258 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,02131077 0,02468014 ! chloride transport GO:0006821 67 48 0,000 0,02175983 0,02518753 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,02175983 0,02517486 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 0,000 0,02175983 0,0251622 ! response to temperature stimulus GO:0009266 62 48 0,000 0,02175983 0,02514956 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,02175983 0,02513693 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,02175983 0,02512431 ! gastrulation GO:0007369 73 48 0,000 0,02175983 0,0251117 ! heart morphogenesis GO:0003007 65 48 0,000 0,02175983 0,02509911 ! regulation of DNA replication GO:0006275 75 48 0,000 0,02175983 0,02508653 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,02175983 0,02507396 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,02175983 0,0250614 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,02175983 0,02504886 ! regulation of endocytosis GO:0030100 63 48 0,000 0,02175983 0,02503633 ! nuclear export GO:0051168 69 48 0,000 0,02175983 0,02502381 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,02175983 0,0250113 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,02175983 0,02499881 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,02220872 0,02550178 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,02220872 0,02548905 ! sensory perception of smell GO:0007608 61 49 0,000 0,02220872 0,02547634 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,02220872 0,02546364 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,02220872 0,02545095 ! RNA elongation GO:0006354 62 49 0,000 0,02220872 0,02543828 ! regulation of intracellular transport GO:0032386 78 49 0,000 0,02220872 0,02542562 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,02220872 0,02541297 ! germ cell development GO:0007281 68 49 0,000 0,02220872 0,02540033 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,02220872 0,02538771 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,02220872 0,02537509 ! cartilage development GO:0051216 70 49 0,000 0,02220872 0,02536249 ! maintenance of location GO:0051235 84 49 0,000 0,02220872 0,02534991 ! regulation of actin filament length GO:0030832 72 50 0,000 0,02265743 0,02584925 ! ear development GO:0043583 72 50 0,000 0,02265743 0,02583644 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,02265743 0,02582363 ! membrane fusion GO:0006944 80 50 0,000 0,02265743 0,02581084 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,02265743 0,02579807 ! lipid modification GO:0030258 73 50 0,000 0,02265743 0,0257853 ! positive regulation of growth GO:0045927 67 50 0,000 0,02265743 0,02577255 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,02265743 0,02575981 ! proton transport GO:0015992 75 50 0,000 0,02265743 0,02574708 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,02265743 0,02573437 ! positive regulation of secretion GO:0051047 71 51 0,000 0,02310596 0,02623085 ! hydrogen transport GO:0006818 77 51 0,000 0,02310596 0,02621791 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,02310596 0,02620498 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 0,000 0,02310596 0,02619207 ! positive regulation of cell migration GO:0030335 92 51 0,000 0,02310596 0,02617917 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,02310596 0,02616628 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,02310596 0,0261534 ! adult behavior GO:0030534 80 51 0,000 0,02310596 0,02614053 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,02310596 0,02612768 ! transition metal ion transport GO:0000041 74 52 0,000 0,02355431 0,02662158 ! regulation of cellular component size GO:0032535 74 52 0,000 0,02355431 0,0266085 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,02355431 0,02659544 ! aging GO:0007568 79 52 0,000 0,02355431 0,02658239 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,02355431 0,02656935 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,02355431 0,02655633 ! establishment of organelle localization GO:0051656 85 52 0,000 0,02355431 0,02654332 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,02400248 0,02703511 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,02400248 0,02702188 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,02400248 0,02700866 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,02400248 0,02699545 ! kidney development GO:0001822 90 53 0,000 0,02400248 0,02698225 ! single fertilization GO:0007338 59 53 0,000 0,02400248 0,02696907 ! cell projection assembly GO:0030031 76 53 0,000 0,02400248 0,0269559 ! amino acid transport GO:0006865 84 54 0,000 0,02445046 0,02744562 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,02445046 0,02743223 ! regulation of mitosis GO:0007088 84 54 0,000 0,02445046 0,02741885 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,02445046 0,02740549 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,02445046 0,02739214 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,02445046 0,0273788 ! DNA catabolic process GO:0006308 67 54 0,000 0,02445046 0,02736548 ! detection of external stimulus GO:0009581 66 54 0,000 0,02445046 0,02735217 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,02445046 0,02733887 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,02445046 0,02732559 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,02445046 0,02731232 ! exocytosis GO:0006887 74 55 0,000 0,02489827 0,02779904 ! mesoderm development GO:0007498 76 55 0,000 0,02489827 0,02778555 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,02489827 0,02777208 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,02489827 0,02775862 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,0253459 0,02824398 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,0253459 0,0282303 ! positive regulation of cell motion GO:0051272 99 56 0,000 0,0253459 0,02821664 ! negative regulation of protein kinase activity GO:0006469 99 57 0,000 0,02579335 0,02870087 ! carbohydrate transport GO:0008643 74 57 0,000 0,02579335 0,02868699 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,02579335 0,02867313 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 0,000 0,02579335 0,02865927 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,02579335 0,02864544 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,02579335 0,02863161 ! camera-type eye development GO:0043010 88 57 0,000 0,02579335 0,0286178 ! secondary metabolic process GO:0019748 84 57 0,000 0,02579335 0,028604 ! response to peptide hormone stimulus GO:0043434 84 57 0,000 0,02579335 0,02859022 ! developmental maturation GO:0021700 75 57 0,000 0,02579335 0,02857644 ! gonad development GO:0008406 79 57 0,000 0,02579335 0,02856269 ! negative regulation of kinase activity GO:0033673 100 58 0,000 0,02624062 0,02904399 ! viral reproductive process GO:0022415 87 58 0,000 0,02624062 0,02903002 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,02624062 0,02901607 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,02624062 0,02900212 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,02624062 0,02898819 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,0266877 0,02946794 ! activation of MAPK activity GO:0000187 84 59 0,000 0,0266877 0,0294538 ! lung development GO:0030324 94 59 0,000 0,0266877 0,02943967 ! actin filament organization GO:0007015 95 59 0,000 0,0266877 0,02942556 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,0266877 0,02941146 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,0266877 0,02939738 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,02713461 0,02987535 ! phosphoinositide metabolic process GO:0030384 87 60 0,000 0,02713461 0,02986106 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,02713461 0,02984678 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,02713461 0,02983251 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,02713461 0,02981826 ! regulation of heart contraction GO:0008016 91 60 0,000 0,02713461 0,02980402 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,02713461 0,02978979 ! fertilization GO:0009566 68 60 0,000 0,02713461 0,02977558 ! regulation of homeostatic process GO:0032844 105 60 0,000 0,02713461 0,02976138 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,02758134 0,03023694 ! meiosis GO:0007126 96 61 0,000 0,02758134 0,03022253 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 114 61 0,000 0,02758134 0,03020814 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,02758134 0,03019376 ! urogenital system development GO:0001655 101 61 0,000 0,02758134 0,0301794 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,02758134 0,03016505 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,02758134 0,03015071 ! extracellular matrix organization GO:0030198 103 61 0,000 0,02758134 0,03013638 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,02758134 0,03012207 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! negative regulation of transferase activity GO:0051348 105 61 0,000 0,02758134 0,03010778 ! amine catabolic process GO:0009310 90 62 0,000 0,02802789 0,03058072 ! neurotransmitter transport GO:0006836 81 62 0,000 0,02802789 0,03056622 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,02802789 0,03055173 ! negative regulation of cell growth GO:0030308 106 62 0,000 0,02802789 0,03053726 ! respiratory tube development GO:0030323 99 62 0,000 0,02802789 0,0305228 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,02802789 0,03050836 ! meiotic cell cycle GO:0051321 97 62 0,000 0,02802789 0,03049392 ! organelle localization GO:0051640 96 62 0,000 0,02802789 0,03047951 ! regulation of transcription factor activity GO:0051090 97 63 0,000 0,02847426 0,03095029 GO:0090046|regulation of transcription regulator activity, ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,02847426 0,03093567 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 0,000 0,02847426 0,03092106 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 0,000 0,02847426 0,03090647 ! viral reproduction GO:0016032 92 63 0,000 0,02847426 0,03089189 ! regulation of lipase activity GO:0060191 109 63 0,000 0,02847426 0,03087733 ! negative regulation of cell size GO:0045792 108 64 0,000 0,02892046 0,03134639 ! appendage morphogenesis GO:0035107 93 64 0,000 0,02892046 0,03133163 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,02892046 0,03131688 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,02892046 0,03130214 ! hexose catabolic process GO:0019320 82 64 0,000 0,02892046 0,03128742 ! respiratory system development GO:0060541 100 64 0,000 0,02892046 0,03127271 ! adaptive immune response GO:0002250 94 64 0,000 0,02892046 0,03125801 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 90 65 0,000 0,02936647 0,03172516 ! regulation of caspase activity GO:0043281 97 65 0,000 0,02936647 0,03171027 ! appendage development GO:0048736 94 65 0,000 0,02936647 0,03169539 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 0,000 0,02936647 0,03168052 ! defense response to bacterium GO:0042742 73 65 0,000 0,02936647 0,03166567 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,02936647 0,03165083 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,02936647 0,03163601 ! activation of immune response GO:0002253 83 65 0,000 0,02936647 0,0316212 ! protein oligomerization GO:0051259 100 65 0,000 0,02936647 0,0316064 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,0298123 0,03207123 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,0298123 0,03205624 ! antigen processing and presentation GO:0019882 96 66 0,000 0,0298123 0,03204126 ! axon guidance GO:0007411 99 66 0,000 0,0298123 0,03202629 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,0298123 0,03201134 ! regulation of immune effector process GO:0002697 101 66 0,000 0,0298123 0,0319964 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,03025795 0,03245956 ! regulation of endopeptidase activity GO:0052548 99 67 0,000 0,03025795 0,03244443 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,03025795 0,03242931 ! acute inflammatory response GO:0002526 92 68 0,000 0,03070343 0,03289142 ! learning or memory GO:0007611 123 68 0,000 0,03070343 0,03287611 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,03070343 0,03286081 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,03070343 0,03284553 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,03070343 0,03283026 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,03070343 0,032815 ! rhythmic process GO:0048511 105 68 0,000 0,03070343 0,03279976 ! inorganic anion transport GO:0015698 93 68 0,000 0,03070343 0,03278453 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,03114872 0,03324458 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,03114872 0,03322916 ! response to drug GO:0042493 108 69 0,000 0,03114872 0,03321375 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,03159384 0,03367277 ! humoral immune response GO:0006959 86 70 0,000 0,03159384 0,03365717 ! eye development GO:0001654 111 70 0,000 0,03159384 0,03364159 ! amine transport GO:0015837 101 70 0,000 0,03159384 0,03362602 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,03159384 0,03361047 ! regulation of catabolic process GO:0009894 106 70 0,000 0,03159384 0,03359493 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,03203878 0,0340523 ! muscle cell differentiation GO:0042692 104 71 0,000 0,03203878 0,03403658 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,03203878 0,03402086 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,03203878 0,03400516 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,03203878 0,03398948 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,03203878 0,03397381 ! regulation of peptidase activity GO:0052547 106 72 0,000 0,03248354 0,03442955 ! response to hypoxia GO:0001666 132 72 0,000 0,03248354 0,03441369 ! negative regulation of organelle organization GO:0010639 115 72 0,000 0,03248354 0,03439785 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,03248354 0,03438202 ! negative regulation of transport GO:0051051 116 73 0,000 0,03292812 0,03483655 ! regulation of blood pressure GO:0008217 107 73 0,000 0,03292812 0,03482054 ! tube morphogenesis GO:0035239 118 73 0,000 0,03292812 0,03480453 ! mitochondrion organization GO:0007005 104 73 0,000 0,03292812 0,03478855 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,03292812 0,03477257 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,03292812 0,03475662 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,03337252 0,03520954 ! response to oxygen levels GO:0070482 137 74 0,000 0,03337252 0,03519339 ! digestion GO:0007586 97 74 0,000 0,03337252 0,03517726 ! protein import into nucleus GO:0006606 118 74 0,000 0,03337252 0,03516115 ! cellular response to hormone stimulus GO:0032870 109 74 0,000 0,03337252 0,03514505 ! positive regulation of lymphocyte activation GO:0051251 108 74 0,000 0,03337252 0,03512896 ! blood coagulation GO:0007596 116 75 0,000 0,03381674 0,03558028 GO:0050817|coagulation, ! negative regulation of growth GO:0045926 123 75 0,000 0,03381674 0,03556401 ! response to nutrient GO:0007584 104 75 0,000 0,03381674 0,03554776 ! nuclear import GO:0051170 121 75 0,000 0,03381674 0,03553152 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,03381674 0,0355153 ! amine biosynthetic process GO:0009309 97 76 0,000 0,03426078 0,03596522 ! tRNA metabolic process GO:0006399 95 76 0,000 0,03426078 0,03594881 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,03426078 0,03593242 ! regulation of protein transport GO:0051223 114 76 0,000 0,03426078 0,03591604 GO:0070201|regulation of establishment of protein localization, ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,03470465 0,03636478 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,03470465 0,03634822 ! regulation of DNA binding GO:0051101 119 77 0,000 0,03470465 0,03633167 ! gland development GO:0048732 148 77 0,000 0,03470465 0,03631514 ! sex differentiation GO:0007548 105 77 0,000 0,03470465 0,03629863 ! protein ubiquitination GO:0016567 125 77 0,000 0,03470465 0,03628213 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,03470465 0,03626565 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,03470465 0,03624918 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,03470465 0,03623272 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,03514833 0,0366793 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,03514833 0,03666266 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,03559184 0,03710845 ! cellular respiration GO:0045333 107 79 0,000 0,03559184 0,03709163 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,03559184 0,03707483 ! T cell activation GO:0042110 134 79 0,000 0,03559184 0,03705805 ! regulation of lyase activity GO:0051339 133 79 0,000 0,03559184 0,03704128 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,03559184 0,03702453 ! chromatin assembly GO:0031497 102 80 0,000 0,03603517 0,03746876 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,03603517 0,03745183 ! protein localization in nucleus GO:0034504 133 80 0,000 0,03603517 0,03743491 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,03603517 0,03741801 ! forebrain development GO:0030900 131 80 0,000 0,03603517 0,03740112 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,03647832 0,037844 ! hemostasis GO:0007599 125 81 0,000 0,03647832 0,03782693 ! mRNA transport GO:0051028 121 81 0,000 0,03647832 0,03780989 ! regulation of cell cycle process GO:0010564 122 81 0,000 0,03647832 0,03779286 ! regulation of neurological system process GO:0031644 122 81 0,000 0,03647832 0,03777584 ! vitamin metabolic process GO:0006766 103 81 0,000 0,03647832 0,03775884 ! positive regulation of cell activation GO:0050867 120 81 0,000 0,03647832 0,03774185 GO:0002696|positive regulation of leukocyte activation, ! ossification GO:0001503 134 82 0,000 0,0369213 0,03818299 GO:0060348|bone development, ! detection of stimulus GO:0051606 108 82 0,000 0,0369213 0,03816583 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,03736409 0,0386062 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,03736409 0,03858887 ! regulation of cell adhesion GO:0030155 159 83 0,000 0,03736409 0,03857155 ! regulation of defense response GO:0031347 117 84 0,000 0,03780671 0,03901096 ! microtubule cytoskeleton organization GO:0000226 120 84 0,000 0,03780671 0,03899346 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,03780671 0,03897599 ! sterol metabolic process GO:0016125 120 84 0,000 0,03780671 0,03895852 ! regulation of DNA metabolic process GO:0051052 135 85 0,000 0,03824915 0,03939679 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,03824915 0,03937916 ! rRNA metabolic process GO:0016072 107 85 0,000 0,03824915 0,03936154 GO:0006364|rRNA processing, ! positive regulation of MAP kinase activity GO:0043406 121 85 0,000 0,03824915 0,03934393 ! transcription initiation GO:0006352 118 85 0,000 0,03824915 0,03932635 ! anterior/posterior pattern formation GO:0009952 124 85 0,000 0,03824915 0,03930877 ! regulation of protein localization GO:0032880 132 85 0,000 0,03824915 0,03929122 ! regulation of membrane potential GO:0042391 128 85 0,000 0,03824915 0,03927368 ! negative regulation of multicellular organismal process GO:0051241 133 85 0,000 0,03824915 0,03925615 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,03869141 0,03969234 ! cell cycle arrest GO:0007050 150 86 0,000 0,03869141 0,03967465 ! nucleosome organization GO:0034728 114 87 0,000 0,03913349 0,04011008 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,03913349 0,04009222 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,03913349 0,04007436 ! skeletal muscle tissue development GO:0007519 123 87 0,000 0,03913349 0,04005653 GO:0060538|skeletal muscle organ development, ! female pregnancy GO:0007565 130 87 0,000 0,03913349 0,04003871 ! Wnt receptor signaling pathway GO:0016055 130 87 0,000 0,03913349 0,04002091 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,03957539 0,04045485 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,03957539 0,04043687 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,03957539 0,04041892 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,03957539 0,04040098 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 0,000 0,03957539 0,04038305 ! regulation of neurogenesis GO:0050767 153 89 0,000 0,04001712 0,04081569 ! reproductive developmental process GO:0003006 127 89 0,000 0,04001712 0,0407976 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,04001712 0,04077952 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,04001712 0,04076146 ! regulation of T cell activation GO:0050863 128 89 0,000 0,04001712 0,04074342 ! leukocyte differentiation GO:0002521 143 90 0,000 0,04045867 0,04117475 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,04045867 0,04115654 ! hormone metabolic process GO:0042445 121 90 0,000 0,04045867 0,04113835 ! RNA localization GO:0006403 135 91 0,000 0,04090004 0,04156876 ! ATP metabolic process GO:0046034 137 91 0,000 0,04090004 0,04155039 ! response to virus GO:0009615 122 91 0,000 0,04090004 0,04153205 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,04134123 0,04196153 ! glycerophospholipid metabolic process GO:0006650 130 92 0,000 0,04134123 0,04194303 ! cell fate commitment GO:0045165 141 92 0,000 0,04134123 0,04192453 ! positive regulation of immune response GO:0050778 121 92 0,000 0,04134123 0,04190605 ! DNA recombination GO:0006310 146 92 0,000 0,04134123 0,04188759 ! sulfur metabolic process GO:0006790 118 92 0,000 0,04134123 0,04186915 ! regulation of cytoskeleton organization GO:0051493 154 93 0,000 0,04178225 0,04229717 ! peptidyl-amino acid modification GO:0018193 147 93 0,000 0,04178225 0,04227856 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,04178225 0,04225997 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,04178225 0,0422414 ! electron transport chain GO:0022900 123 94 0,000 0,04222309 0,04266832 ! response to oxidative stress GO:0006979 141 94 0,000 0,04222309 0,04264958 ! regulation of binding GO:0051098 151 95 0,000 0,04266375 0,04307578 ! angiogenesis GO:0001525 149 95 0,000 0,04266375 0,04305688 ! carboxylic acid transport GO:0046942 147 95 0,000 0,04266375 0,04303799 GO:0015849|organic acid transport, ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,04310423 0,04346328 ! in utero embryonic development GO:0001701 147 96 0,000 0,04310423 0,04344423 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,04310423 0,0434252 ! regulation of cellular component biogenesis GO:0044087 158 96 0,000 0,04310423 0,04340619 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,04310423 0,04338719 ! protein maturation GO:0051604 129 96 0,000 0,04310423 0,04336821 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,04354454 0,04379206 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,04354454 0,04377292 ! calcium ion transport GO:0006816 167 99 0,000 0,04442462 0,04463811 ! extracellular structure organization GO:0043062 156 99 0,000 0,04442462 0,04461861 ! protein import GO:0017038 156 99 0,000 0,04442462 0,04459914 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 0,000 0,04442462 0,04457968 ! regulation of translation GO:0006417 151 100 0,000 0,0448644 0,04500136 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,0448644 0,04498174 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,0448644 0,04496214 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,0448644 0,04494256 ! divalent metal ion transport GO:0070838 171 100 0,000 0,0448644 0,04492299 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,0448644 0,04490344 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,0448644 0,04488391 ! protein localization in organelle GO:0033365 161 100 0,000 0,0448644 0,0448644