pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-b2/out-0.05-06-0.01-300-run-b2//th1-pval-1e-01-06-th2-pval-1e-02-02-th3-pval-1e-01-01-run-b2/go_data/8812-10-real-IPC-NIBC-129-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 3,000 2,913E-09 7,116E-06 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 1,000 1,566E-06 1,913E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 2,922E-06 2,38E-03 ! regulation of vascular permeability GO:0043114 12 8 1,000 2,922E-06 1,785E-03 ! icosanoid secretion GO:0032309 15 9 1,000 3,757E-06 1,835E-03 GO:0050482|arachidonic acid secretion, ! interphase of mitotic cell cycle GO:0051329 224 98 2,000 4,391E-06 1,788E-03 ! acid secretion GO:0046717 20 11 1,000 5,737E-06 2,002E-03 ! thymus development GO:0048538 29 11 1,000 5,737E-06 1,752E-03 ! T cell homeostasis GO:0043029 28 12 1,000 6,883E-06 1,868E-03 ! lymphocyte homeostasis GO:0002260 33 15 1,000 1,094E-05 2,674E-03 ! long-chain fatty acid transport GO:0015909 32 18 1,000 1,594E-05 3,54E-03 ! G1 phase of mitotic cell cycle GO:0000080 39 19 1,000 1,781E-05 3,626E-03 ! cellular response to unfolded protein GO:0034620 35 20 1,000 1,979E-05 3,718E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! smooth muscle contraction GO:0006939 48 21 1,000 2,186E-05 3,815E-03 ! regulation of vasoconstriction GO:0019229 40 21 1,000 2,186E-05 3,561E-03 ! G1 phase GO:0051318 44 22 1,000 2,405E-05 3,671E-03 ! fatty acid transport GO:0015908 47 23 1,000 2,633E-05 3,784E-03 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 1,000 3,121E-05 4,236E-03 ! leukocyte homeostasis GO:0001776 50 25 1,000 3,121E-05 4,013E-03 ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 3,381E-05 4,129E-03 ! fat cell differentiation GO:0045444 57 28 1,000 3,93E-05 4,572E-03 ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 4,221E-05 4,687E-03 ! monocarboxylic acid transport GO:0015718 93 43 1,000 9,363E-05 9,945E-03 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 1,000 1,073E-04 0,01091746 ! positive regulation of cell cycle GO:0045787 96 48 1,000 1,168E-04 0,01141823 ! vascular process in circulatory system GO:0003018 85 48 1,000 1,168E-04 0,01097907 ! response to calcium ion GO:0051592 94 49 1,000 1,218E-04 0,01102026 ! response to UV GO:0009411 120 55 1,000 1,536E-04 0,0134038 ! regulation of DNA replication GO:0006275 105 56 1,000 1,593E-04 0,0134184 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 1,000 2,351E-04 0,01914401 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 1,000 2,421E-04 0,01907591 ! homeostasis of number of cells GO:0048872 131 69 1,000 2,421E-04 0,01847979 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 1,000 2,636E-04 0,01951289 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 1,000 2,636E-04 0,01893898 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 1,000 2,784E-04 0,01943427 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 1,000 2,937E-04 0,01992926 ! cytosolic calcium ion homeostasis GO:0051480 149 77 1,000 3,015E-04 0,01990398 ! positive regulation of ligase activity GO:0051351 130 77 1,000 3,015E-04 0,01938019 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 1,000 3,173E-04 0,01987612 ! positive regulation of phosphorylation GO:0042327 149 81 1,000 3,336E-04 0,02037167 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 3,502E-04 0,02086684 GO:0045937|positive regulation of phosphate metabolic process, ! response to metal ion GO:0010038 158 84 1,000 3,587E-04 0,02086293 ! regulation of ligase activity GO:0051340 147 84 1,000 3,587E-04 0,02037775 ! response to inorganic substance GO:0010035 173 90 1,000 4,116E-04 0,0228538 ! positive regulation of protein modification process GO:0031401 156 90 1,000 4,116E-04 0,02234593 ! response to unfolded protein GO:0006986 139 90 1,000 4,116E-04 0,02186015 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 1,000 4,394E-04 0,02284058 GO:0010498|proteasomal protein catabolic process, ! response to protein stimulus GO:0051789 158 96 1,000 4,681E-04 0,02382558 ! regulation of DNA metabolic process GO:0051052 188 97 1,000 4,779E-04 0,02382623 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 1,687E-03 0,08242702 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 1,687E-03 0,0808108 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 1,687E-03 0,07925675 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 1,687E-03 0,07776134 ! positive regulation of helicase activity GO:0051096 12 5 0,000 1,687E-03 0,07632131 ! neuron fate determination GO:0048664 7 5 0,000 1,687E-03 0,07493365 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 1,687E-03 0,07359555 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 1,687E-03 0,0723044 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 1,687E-03 0,07105777 ! polyol transport GO:0015791 12 5 0,000 1,687E-03 0,06985341 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 1,687E-03 0,06868918 ! response to superoxide GO:0000303 10 5 0,000 1,687E-03 0,06756313 ! negative regulation of bone resorption GO:0045779 10 5 0,000 1,687E-03 0,0664734 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 1,687E-03 0,06541827 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 1,687E-03 0,06439611 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 1,687E-03 0,0634054 ! female meiosis GO:0007143 10 5 0,000 1,687E-03 0,06244471 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 1,687E-03 0,0615127 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 1,687E-03 0,0606081 ! hypothalamus development GO:0021854 9 5 0,000 1,687E-03 0,05972972 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 1,687E-03 0,05887644 ! cobalt ion transport GO:0006824 11 5 0,000 1,687E-03 0,0580472 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 1,687E-03 0,05724099 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 1,687E-03 0,05645686 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 1,687E-03 0,05569393 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 1,687E-03 0,05495135 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 1,687E-03 0,0542283 ! embryonic camera-type eye development GO:0031076 12 5 0,000 1,687E-03 0,05352404 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 1,687E-03 0,05283783 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 1,687E-03 0,052169 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 1,687E-03 0,05151689 ! transposition GO:0032196 9 5 0,000 1,687E-03 0,05088088 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 1,687E-03 0,05026038 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 1,687E-03 0,04965483 ! negative chemotaxis GO:0050919 16 5 0,000 1,687E-03 0,0490637 ! positive regulation of histone modification GO:0031058 6 5 0,000 1,687E-03 0,04848648 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 1,687E-03 0,04792269 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 1,687E-03 0,04737185 ! behavioral response to pain GO:0048266 10 5 0,000 1,687E-03 0,04683353 ! clathrin coat assembly GO:0048268 15 5 0,000 1,687E-03 0,04630731 ! Notch receptor processing GO:0007220 11 5 0,000 1,687E-03 0,04579279 ! regulation of dopamine uptake GO:0051584 9 5 0,000 1,687E-03 0,04528957 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 1,687E-03 0,04479729 ! micturition GO:0060073 9 5 0,000 1,687E-03 0,0443156 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 1,687E-03 0,04384416 ! copulation GO:0007620 9 5 0,000 1,687E-03 0,04338264 ! glial cell fate commitment GO:0021781 14 5 0,000 1,687E-03 0,04293074 ! protein maturation by protein folding GO:0022417 14 5 0,000 1,687E-03 0,04248815 ! bioluminescence GO:0008218 9 5 0,000 1,687E-03 0,0420546 ! spermidine metabolic process GO:0008216 7 5 0,000 1,687E-03 0,04162981 ! regulation of potassium ion transport GO:0043266 10 5 0,000 1,687E-03 0,04121351 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 1,687E-03 0,04080545 ! apoptotic cell clearance GO:0043277 23 5 0,000 1,687E-03 0,0404054 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 1,687E-03 0,04001312 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 1,687E-03 0,03962837 ! lipoprotein particle clearance GO:0034381 10 5 0,000 1,687E-03 0,03925096 ! grooming behavior GO:0007625 6 5 0,000 1,687E-03 0,03888067 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 1,687E-03 0,0385173 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 1,687E-03 0,03816066 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 1,687E-03 0,03781056 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 1,687E-03 0,03746683 ! response to protozoan GO:0001562 13 5 0,000 1,687E-03 0,03712929 ! positive regulation of glycolysis GO:0045821 13 5 0,000 1,687E-03 0,03679778 ! lymph vessel development GO:0001945 10 5 0,000 1,687E-03 0,03647213 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 1,687E-03 0,0361522 ! endochondral ossification GO:0001958 17 5 0,000 1,687E-03 0,03583783 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 1,687E-03 0,03552889 ! single strand break repair GO:0000012 8 5 0,000 1,687E-03 0,03522522 ! parathyroid gland development GO:0060017 14 5 0,000 1,687E-03 0,0349267 ! anagen GO:0042640 7 5 0,000 1,687E-03 0,0346332 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 1,687E-03 0,03434459 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 1,687E-03 0,03406075 ! cytokine secretion GO:0050663 15 5 0,000 1,687E-03 0,03378156 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 1,687E-03 0,03350692 ! ceramide catabolic process GO:0046514 7 5 0,000 1,687E-03 0,0332367 ! skeletal myofibril assembly GO:0014866 12 5 0,000 1,687E-03 0,03297081 ! smooth muscle tissue development GO:0048745 32 5 0,000 1,687E-03 0,03270913 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 1,687E-03 0,03245158 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 1,687E-03 0,03219805 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 1,687E-03 0,03194846 ! cardiac muscle fiber development GO:0048739 12 5 0,000 1,687E-03 0,0317027 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 1,687E-03 0,03146069 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 1,687E-03 0,03122236 ! neutrophil mediated immunity GO:0002446 7 5 0,000 1,687E-03 0,0309876 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 1,687E-03 0,03075635 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 1,687E-03 0,03052853 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 1,687E-03 0,03030405 ! glycine biosynthetic process GO:0006545 7 5 0,000 1,687E-03 0,03008285 ! microvillus organization GO:0032528 8 5 0,000 1,687E-03 0,02986486 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 1,687E-03 0,02965001 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 1,687E-03 0,02943822 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 1,687E-03 0,02922944 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 1,687E-03 0,0290236 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 1,687E-03 0,02882064 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 1,687E-03 0,02862049 ! polyol catabolic process GO:0046174 9 5 0,000 1,687E-03 0,02842311 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 1,687E-03 0,02822843 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 1,687E-03 0,0280364 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 1,687E-03 0,02784697 ! muscle cell migration GO:0014812 8 5 0,000 1,687E-03 0,02766007 ! mitochondrial fission GO:0000266 8 5 0,000 1,687E-03 0,02747567 ! sister chromatid cohesion GO:0007062 15 5 0,000 1,687E-03 0,02729371 ! response to tumor necrosis factor GO:0034612 10 5 0,000 1,687E-03 0,02711415 ! mRNA transcription GO:0009299 10 5 0,000 1,687E-03 0,02693693 ! nerve growth factor processing GO:0032455 9 5 0,000 1,687E-03 0,02676202 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 1,687E-03 0,02658936 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 1,687E-03 0,02641892 ! anaerobic glycolysis GO:0019642 6 5 0,000 1,687E-03 0,02625064 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 1,687E-03 0,0260845 ! monocyte activation GO:0042117 10 5 0,000 1,687E-03 0,02592045 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 1,687E-03 0,02575844 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 1,687E-03 0,02559845 ! response to food GO:0032094 6 5 0,000 1,687E-03 0,02544044 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 1,687E-03 0,02528436 ! positive regulation of transporter activity GO:0032411 8 5 0,000 1,687E-03 0,02513019 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 1,687E-03 0,02497788 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 1,687E-03 0,02482742 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 1,687E-03 0,02467875 ! forebrain neuron development GO:0021884 13 5 0,000 1,687E-03 0,02453185 ! lipoprotein catabolic process GO:0042159 11 5 0,000 1,687E-03 0,02438669 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 1,687E-03 0,02424324 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 1,687E-03 0,02410147 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 1,687E-03 0,02396134 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 1,687E-03 0,02382284 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 1,687E-03 0,02368592 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 1,687E-03 0,02355058 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 1,687E-03 0,02341677 ! lipid glycosylation GO:0030259 7 5 0,000 1,687E-03 0,02328447 ! nucleobase transport GO:0015851 6 5 0,000 1,687E-03 0,02315366 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 1,687E-03 0,02302431 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 1,687E-03 0,02289639 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 1,687E-03 0,02276989 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 1,687E-03 0,02264479 ! basic amino acid transport GO:0015802 12 5 0,000 1,687E-03 0,02252104 ! cellular glucose homeostasis GO:0001678 6 5 0,000 1,687E-03 0,02239865 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 1,687E-03 0,02227757 ! actin nucleation GO:0045010 11 5 0,000 1,687E-03 0,0221578 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 1,687E-03 0,02203931 ! depurination GO:0045007 5 5 0,000 1,687E-03 0,02192208 ! depyrimidination GO:0045008 10 5 0,000 1,687E-03 0,02180609 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 1,687E-03 0,02169132 ! regulation of centrosome cycle GO:0046605 7 5 0,000 1,687E-03 0,02157775 ! G2/M transition checkpoint GO:0031576 8 5 0,000 1,687E-03 0,02146537 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 1,687E-03 0,02135415 ! zinc ion homeostasis GO:0055069 9 5 0,000 1,687E-03 0,02124408 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 1,687E-03 0,02113513 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 1,687E-03 0,0210273 ! forebrain morphogenesis GO:0048853 13 5 0,000 1,687E-03 0,02092056 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 1,687E-03 0,0208149 ! activated T cell proliferation GO:0050798 16 5 0,000 1,687E-03 0,02071031 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 1,687E-03 0,02060675 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 1,687E-03 0,02050423 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 1,687E-03 0,02040273 ! positive regulation of organ growth GO:0046622 6 5 0,000 1,687E-03 0,02030222 ! gamma-delta T cell activation GO:0046629 6 5 0,000 1,687E-03 0,0202027 ! response to arsenic GO:0046685 11 5 0,000 1,687E-03 0,02010415 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 1,687E-03 0,02000656 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 1,687E-03 0,01990991 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 1,687E-03 0,01981419 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 1,687E-03 0,01971938 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 1,687E-03 0,01962548 ! response to mercury ion GO:0046689 8 5 0,000 1,687E-03 0,01953247 ! response to cadmium ion GO:0046686 7 5 0,000 1,687E-03 0,01944033 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 1,687E-03 0,01934907 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 1,687E-03 0,01925865 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 1,687E-03 0,01916907 ! bile acid biosynthetic process GO:0006699 7 5 0,000 1,687E-03 0,01908033 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 1,687E-03 0,0189924 ! ganglioside catabolic process GO:0006689 12 5 0,000 1,687E-03 0,01890528 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 1,687E-03 0,01881895 ! decidualization GO:0046697 11 5 0,000 1,687E-03 0,01873341 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 1,687E-03 0,01864865 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 1,687E-03 0,01856464 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 1,687E-03 0,01848139 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 1,687E-03 0,01839889 ! embryonic cleavage GO:0040016 6 5 0,000 1,687E-03 0,01831712 ! peroxisome fission GO:0016559 5 5 0,000 1,687E-03 0,01823607 ! histone demethylation GO:0016577 13 5 0,000 1,687E-03 0,01815573 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 1,687E-03 0,0180761 ! mitotic recombination GO:0006312 9 5 0,000 1,687E-03 0,01799717 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 1,687E-03 0,01791892 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 1,687E-03 0,01784135 ! metaphase plate congression GO:0051310 7 5 0,000 1,687E-03 0,01776444 ! regulation of sterol transport GO:0032371 7 5 0,000 1,687E-03 0,0176882 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 1,687E-03 0,01761261 ! enteric nervous system development GO:0048484 8 5 0,000 1,687E-03 0,01753766 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 1,687E-03 0,01746335 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 1,687E-03 0,01738967 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 1,687E-03 0,0173166 ! muscle cell proliferation GO:0033002 12 5 0,000 1,687E-03 0,01724415 ! skeletal muscle regeneration GO:0043403 8 5 0,000 1,687E-03 0,0171723 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 1,687E-03 0,01710104 ! B cell homeostasis GO:0001782 13 5 0,000 1,687E-03 0,01703038 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 1,687E-03 0,01696029 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 1,687E-03 0,01689078 ! metaphase GO:0051323 11 5 0,000 1,687E-03 0,01682184 ! melatonin biosynthetic process GO:0030187 7 5 0,000 1,687E-03 0,01675346 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 1,687E-03 0,01668563 ! cellular response to nutrient GO:0031670 8 5 0,000 1,687E-03 0,01661835 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 1,687E-03 0,01655161 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 1,687E-03 0,0164854 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 1,687E-03 0,01641972 ! regulation of hair follicle development GO:0051797 10 5 0,000 1,687E-03 0,01635457 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 1,687E-03 0,01628992 ! response to redox state GO:0051775 6 5 0,000 1,687E-03 0,01622579 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 1,687E-03 0,01616216 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 1,687E-03 0,01609903 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 1,687E-03 0,01603638 ! brown fat cell differentiation GO:0050873 7 5 0,000 1,687E-03 0,01597423 ! regulation of telomerase activity GO:0051972 7 5 0,000 1,687E-03 0,01591255 ! galactolipid metabolic process GO:0019374 7 5 0,000 1,687E-03 0,01585135 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 1,687E-03 0,01579062 ! porphyrin catabolic process GO:0006787 12 5 0,000 1,687E-03 0,01573035 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 1,687E-03 0,01567054 ! striatum development GO:0021756 14 5 0,000 1,687E-03 0,01561118 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 1,687E-03 0,01555227 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 1,687E-03 0,0154938 ! glial cell migration GO:0008347 10 5 0,000 1,687E-03 0,01543577 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 1,687E-03 0,01537818 ! neural plate morphogenesis GO:0001839 7 5 0,000 1,687E-03 0,01532101 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 1,687E-03 0,01526426 ! somatic stem cell maintenance GO:0035019 15 5 0,000 1,687E-03 0,01520794 ! T cell activation during immune response GO:0002286 9 5 0,000 1,687E-03 0,01515203 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 1,687E-03 0,01509652 ! negative regulation of lipase activity GO:0060192 8 5 0,000 1,687E-03 0,01504143 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 1,687E-03 0,01498673 ! neuroprotection GO:0043526 8 5 0,000 1,687E-03 0,01493243 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 1,687E-03 0,01487852 ! regulation of sensory perception GO:0051931 8 5 0,000 1,687E-03 0,014825 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 1,687E-03 0,01477187 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 1,687E-03 0,01471911 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 1,687E-03 0,01466673 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 1,687E-03 0,01461472 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 1,687E-03 0,01456308 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 1,687E-03 0,0145118 ! sequestering of calcium ion GO:0051208 7 5 0,000 1,687E-03 0,01446088 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 1,687E-03 0,01441032 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 1,687E-03 0,01436011 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 1,687E-03 0,01431025 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 1,687E-03 0,01426073 ! spindle assembly GO:0051225 6 5 0,000 1,687E-03 0,01421155 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 1,687E-03 0,01416272 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 1,687E-03 0,01411422 ! protein palmitoylation GO:0018345 12 5 0,000 1,687E-03 0,01406604 ! drug metabolic process GO:0017144 7 5 0,000 1,687E-03 0,0140182 ! stem cell division GO:0017145 11 5 0,000 1,687E-03 0,01397068 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 1,687E-03 0,01392348 ! organ regeneration GO:0031100 7 5 0,000 1,687E-03 0,0138766 ! carnitine metabolic process GO:0009437 8 5 0,000 1,687E-03 0,01383004 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 1,687E-03 0,01378378 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 2,024E-03 0,01648285 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 2,024E-03 0,01642809 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 2,024E-03 0,0163737 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 2,024E-03 0,01631966 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 2,024E-03 0,01626597 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 2,024E-03 0,01621264 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 2,024E-03 0,01615966 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 2,024E-03 0,01610702 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 2,024E-03 0,01605473 ! response to oxygen radical GO:0000305 11 6 0,000 2,024E-03 0,01600277 ! positive regulation of axon extension GO:0045773 13 6 0,000 2,024E-03 0,01595115 ! myoblast cell fate commitment GO:0048625 18 6 0,000 2,024E-03 0,01589986 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 2,024E-03 0,0158489 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 2,024E-03 0,01579826 ! regulation of interferon-beta production GO:0032648 8 6 0,000 2,024E-03 0,01574795 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 2,024E-03 0,01569796 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 2,024E-03 0,01564828 ! forebrain regionalization GO:0021871 9 6 0,000 2,024E-03 0,01559891 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 2,024E-03 0,01554986 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 2,024E-03 0,01550112 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 2,024E-03 0,01545267 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 2,024E-03 0,01540454 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 2,024E-03 0,0153567 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 2,024E-03 0,01530915 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 2,024E-03 0,0152619 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 2,024E-03 0,01521494 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 2,024E-03 0,01516827 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 2,024E-03 0,01512188 ! malate metabolic process GO:0006108 13 6 0,000 2,024E-03 0,01507578 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 2,024E-03 0,01502996 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 2,024E-03 0,01498441 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 2,024E-03 0,01493914 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 2,024E-03 0,01489414 ! protein refolding GO:0042026 15 6 0,000 2,024E-03 0,01484942 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 2,024E-03 0,01480496 ! opsonization GO:0008228 8 6 0,000 2,024E-03 0,01476076 ! mating behavior GO:0007617 7 6 0,000 2,024E-03 0,01471683 ! erythrocyte maturation GO:0043249 8 6 0,000 2,024E-03 0,01467316 ! embryonic hemopoiesis GO:0035162 16 6 0,000 2,024E-03 0,01462975 ! protein amino acid dealkylation GO:0008214 15 6 0,000 2,024E-03 0,0145866 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 2,024E-03 0,01454369 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 2,024E-03 0,01450104 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 2,024E-03 0,01445864 ! response to interferon-gamma GO:0034341 16 6 0,000 2,024E-03 0,01441649 ! toxin metabolic process GO:0009404 11 6 0,000 2,024E-03 0,01437458 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 2,024E-03 0,01433292 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 2,024E-03 0,01429149 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 2,024E-03 0,01425031 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 2,024E-03 0,01420936 ! cGMP-mediated signaling GO:0019934 14 6 0,000 2,024E-03 0,01416864 ! dorsal spinal cord development GO:0021516 10 6 0,000 2,024E-03 0,01412816 ! activation of MAPKKK activity GO:0000185 12 6 0,000 2,024E-03 0,01408791 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 2,024E-03 0,01404789 ! thymic T cell selection GO:0045061 16 6 0,000 2,024E-03 0,01400809 ! sphingoid catabolic process GO:0046521 8 6 0,000 2,024E-03 0,01396852 ! protein lipoylation GO:0009249 10 6 0,000 2,024E-03 0,01392917 ! transepithelial chloride transport GO:0030321 12 6 0,000 2,024E-03 0,01389004 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 2,024E-03 0,01385114 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 2,024E-03 0,01381245 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 2,024E-03 0,01377397 ! glutamate catabolic process GO:0006538 12 6 0,000 2,024E-03 0,01373571 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 2,024E-03 0,01369766 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 2,024E-03 0,01365982 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 2,024E-03 0,01362219 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 2,024E-03 0,01358477 ! hyperosmotic response GO:0006972 10 6 0,000 2,024E-03 0,01354755 ! L-serine biosynthetic process GO:0006564 7 6 0,000 2,024E-03 0,01351054 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 2,024E-03 0,01347372 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 2,024E-03 0,01343711 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 2,024E-03 0,01340069 ! urea metabolic process GO:0019627 7 6 0,000 2,024E-03 0,01336448 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 2,024E-03 0,01332845 ! neutrophil activation GO:0042119 7 6 0,000 2,024E-03 0,01329262 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 2,024E-03 0,01325699 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 2,024E-03 0,01322154 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 2,024E-03 0,01318628 ! paraxial mesoderm development GO:0048339 16 6 0,000 2,024E-03 0,01315121 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 2,024E-03 0,01311633 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 2,024E-03 0,01308163 ! neuron apoptosis GO:0051402 15 6 0,000 2,024E-03 0,01304711 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 2,024E-03 0,01301278 ! T cell mediated immunity GO:0002456 17 6 0,000 2,024E-03 0,01297862 ! negative regulation of platelet activation GO:0010544 9 6 0,000 2,024E-03 0,01294465 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 2,024E-03 0,01291085 ! carnitine transport GO:0015879 10 6 0,000 2,024E-03 0,01287723 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 2,024E-03 0,01284378 ! positive regulation of exocytosis GO:0045921 11 6 0,000 2,024E-03 0,01281051 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 2,024E-03 0,01277741 ! early endosome to late endosome transport GO:0045022 16 6 0,000 2,024E-03 0,01274447 ! 5S class rRNA transcription GO:0042791 13 6 0,000 2,024E-03 0,01271171 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 2,024E-03 0,01267912 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 2,024E-03 0,01264669 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 2,024E-03 0,01261443 ! sodium ion homeostasis GO:0055078 12 6 0,000 2,024E-03 0,01258233 ! establishment of spindle localization GO:0051293 16 6 0,000 2,024E-03 0,0125504 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 2,024E-03 0,01251862 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 2,024E-03 0,01248701 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 2,024E-03 0,01245556 ! response to UV-C GO:0010225 14 6 0,000 2,024E-03 0,01242426 ! astrocyte development GO:0014002 16 6 0,000 2,024E-03 0,01239312 ! protein targeting to lysosome GO:0006622 12 6 0,000 2,024E-03 0,01236214 ! purine base biosynthetic process GO:0009113 17 6 0,000 2,024E-03 0,01233131 ! interaction with symbiont GO:0051702 14 6 0,000 2,024E-03 0,01230064 ! regulation of dendrite development GO:0050773 16 6 0,000 2,024E-03 0,01227011 ! peptidyl-arginine modification GO:0018195 13 6 0,000 2,024E-03 0,01223974 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 2,024E-03 0,01220952 ! response to copper ion GO:0046688 10 6 0,000 2,024E-03 0,01217945 ! response to exogenous dsRNA GO:0043330 13 6 0,000 2,024E-03 0,01214952 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 2,024E-03 0,01211974 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 2,024E-03 0,01209011 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 2,024E-03 0,01206062 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 2,024E-03 0,01203128 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 2,024E-03 0,01200208 ! regulation of dopamine secretion GO:0014059 14 6 0,000 2,024E-03 0,01197302 ! nucleoside catabolic process GO:0009164 10 6 0,000 2,024E-03 0,0119441 ! hair follicle maturation GO:0048820 8 6 0,000 2,024E-03 0,01191532 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 2,024E-03 0,01188667 ! Schwann cell development GO:0014044 15 6 0,000 2,024E-03 0,01185817 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 2,024E-03 0,0118298 ! response to pheromone GO:0019236 6 6 0,000 2,024E-03 0,01180157 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 2,024E-03 0,01177347 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 2,024E-03 0,0117455 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 2,024E-03 0,01171767 ! base conversion or substitution editing GO:0016553 6 6 0,000 2,024E-03 0,01168997 ! subpallium development GO:0021544 15 6 0,000 2,024E-03 0,0116624 ! neural tube patterning GO:0021532 8 6 0,000 2,024E-03 0,01163496 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 2,024E-03 0,01160764 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 2,024E-03 0,01158046 ! maintenance of organ identity GO:0048496 9 6 0,000 2,024E-03 0,0115534 ! G2 phase GO:0051319 16 6 0,000 2,024E-03 0,01152647 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 2,024E-03 0,01149966 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 2,024E-03 0,01147298 ! oxygen homeostasis GO:0032364 10 6 0,000 2,024E-03 0,01144643 ! establishment of planar polarity GO:0001736 7 6 0,000 2,024E-03 0,01141999 ! regulation of mast cell activation GO:0033003 13 6 0,000 2,024E-03 0,01139368 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 2,024E-03 0,01136748 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 2,024E-03 0,01134141 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 2,024E-03 0,01131546 ! receptor internalization GO:0031623 11 6 0,000 2,024E-03 0,01128963 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 2,024E-03 0,01126391 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 2,024E-03 0,01123831 ! neutrophil homeostasis GO:0001780 11 6 0,000 2,024E-03 0,01121283 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 2,024E-03 0,01118746 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 2,024E-03 0,0111622 ! protein deubiquitination GO:0016579 16 6 0,000 2,024E-03 0,01113706 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 2,024E-03 0,01111204 ! protein destabilization GO:0031648 9 6 0,000 2,024E-03 0,01108712 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 2,024E-03 0,01106232 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 2,024E-03 0,01103762 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 2,024E-03 0,01101304 ! regulation of viral transcription GO:0046782 11 6 0,000 2,024E-03 0,01098857 ! progesterone metabolic process GO:0042448 12 6 0,000 2,024E-03 0,0109642 ! negative regulation of axon extension GO:0030517 24 6 0,000 2,024E-03 0,01093995 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 2,024E-03 0,0109158 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 2,024E-03 0,01089175 ! triglyceride catabolic process GO:0019433 10 6 0,000 2,024E-03 0,01086782 ! determination of adult lifespan GO:0008340 17 6 0,000 2,024E-03 0,01084398 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 2,024E-03 0,01082025 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 2,024E-03 0,01079663 ! neural plate development GO:0001840 9 6 0,000 2,024E-03 0,01077311 ! catecholamine transport GO:0051937 9 6 0,000 2,024E-03 0,01074969 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 2,024E-03 0,01072637 ! sensory cilium assembly GO:0035058 10 6 0,000 2,024E-03 0,01070315 ! organ or tissue specific immune response GO:0002251 8 6 0,000 2,024E-03 0,01068003 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 2,024E-03 0,01065702 ! maternal placenta development GO:0001893 12 6 0,000 2,024E-03 0,0106341 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 2,024E-03 0,01061128 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 2,024E-03 0,01058856 ! negative regulation of B cell activation GO:0050869 14 6 0,000 2,024E-03 0,01056593 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 2,024E-03 0,0105434 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 2,024E-03 0,01052097 ! positive regulation of coagulation GO:0050820 13 6 0,000 2,024E-03 0,01049863 ! cellular anion homeostasis GO:0030002 11 6 0,000 2,024E-03 0,01047639 GO:0055081|anion homeostasis, ! tRNA transcription GO:0009304 17 7 0,000 2,361E-03 0,01219473 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 2,361E-03 0,012169 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 2,361E-03 0,01214338 ! behavioral response to cocaine GO:0048148 14 7 0,000 2,361E-03 0,01211787 ! regulation of helicase activity GO:0051095 16 7 0,000 2,361E-03 0,01209247 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 2,361E-03 0,01206717 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 2,361E-03 0,01204197 ! sleep GO:0030431 16 7 0,000 2,361E-03 0,01201689 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 2,361E-03 0,0119919 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 2,361E-03 0,01196702 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 2,361E-03 0,01194225 ! prostate gland development GO:0030850 14 7 0,000 2,361E-03 0,01191757 ! nucleotide-sugar transport GO:0015780 11 7 0,000 2,361E-03 0,011893 ! synaptonemal complex assembly GO:0007130 10 7 0,000 2,361E-03 0,01186853 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 2,361E-03 0,01184416 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 2,361E-03 0,01181989 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 2,361E-03 0,01179572 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 2,361E-03 0,01177164 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 2,361E-03 0,01174767 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 2,361E-03 0,01172379 ! SMAD protein complex assembly GO:0007183 13 7 0,000 2,361E-03 0,01170001 ! glycolipid transport GO:0046836 11 7 0,000 2,361E-03 0,01167633 ! protein amino acid sulfation GO:0006477 10 7 0,000 2,361E-03 0,01165274 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 2,361E-03 0,01162925 ! neuron adhesion GO:0007158 14 7 0,000 2,361E-03 0,01160585 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 2,361E-03 0,01158254 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 2,361E-03 0,01155933 ! establishment of tissue polarity GO:0007164 8 7 0,000 2,361E-03 0,01153621 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 2,361E-03 0,01151319 ! mRNA stabilization GO:0048255 18 7 0,000 2,361E-03 0,01149025 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 2,361E-03 0,01146741 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 2,361E-03 0,01144465 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 2,361E-03 0,01142199 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 2,361E-03 0,01139942 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 2,361E-03 0,01137693 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 2,361E-03 0,01135454 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 2,361E-03 0,01133223 ! lipoprotein transport GO:0042953 14 7 0,000 2,361E-03 0,01131001 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 2,361E-03 0,01128788 ! rhythmic behavior GO:0007622 17 7 0,000 2,361E-03 0,01126583 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 2,361E-03 0,01124387 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 2,361E-03 0,011222 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 2,361E-03 0,01120021 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 2,361E-03 0,0111785 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 2,361E-03 0,01115688 ! regulation of odontogenesis GO:0042481 14 7 0,000 2,361E-03 0,01113534 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 2,361E-03 0,01111388 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 2,361E-03 0,01109251 ! mechanosensory behavior GO:0007638 16 7 0,000 2,361E-03 0,01107122 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 2,361E-03 0,01105001 ! positive regulation of isotype switching GO:0045830 17 7 0,000 2,361E-03 0,01102888 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 2,361E-03 0,01100784 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 2,361E-03 0,01098687 ! protein-cofactor linkage GO:0018065 13 7 0,000 2,361E-03 0,01096598 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 2,361E-03 0,01094517 ! spinal cord patterning GO:0021511 14 7 0,000 2,361E-03 0,01092444 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 2,361E-03 0,01090379 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 2,361E-03 0,01088322 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 2,361E-03 0,01086272 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 2,361E-03 0,0108423 ! adrenal gland development GO:0030325 17 7 0,000 2,361E-03 0,01082196 ! cysteine metabolic process GO:0006534 13 7 0,000 2,361E-03 0,0108017 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 2,361E-03 0,01078151 ! ovulation GO:0030728 10 7 0,000 2,361E-03 0,01076139 ! adenohypophysis development GO:0021984 11 7 0,000 2,361E-03 0,01074135 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 2,361E-03 0,01072139 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 2,361E-03 0,0107015 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 2,361E-03 0,01068168 ! microtubule nucleation GO:0007020 21 7 0,000 2,361E-03 0,01066193 ! proline biosynthetic process GO:0006561 10 7 0,000 2,361E-03 0,01064226 ! tryptophan metabolic process GO:0006568 11 7 0,000 2,361E-03 0,01062266 ! thyroid hormone generation GO:0006590 13 7 0,000 2,361E-03 0,01060314 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 2,361E-03 0,01058368 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 2,361E-03 0,0105643 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 2,361E-03 0,01054498 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 2,361E-03 0,01052574 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 2,361E-03 0,01050657 ! galactose metabolic process GO:0006012 13 7 0,000 2,361E-03 0,01048747 ! vesicle fusion GO:0006906 20 7 0,000 2,361E-03 0,01046843 ! response to dietary excess GO:0002021 8 7 0,000 2,361E-03 0,01044947 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 2,361E-03 0,01043057 ! intracellular pH reduction GO:0051452 13 7 0,000 2,361E-03 0,01041174 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 2,361E-03 0,01039298 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 2,361E-03 0,01037429 ! organ growth GO:0035265 15 7 0,000 2,361E-03 0,01035567 ! nucleoside transport GO:0015858 11 7 0,000 2,361E-03 0,01033711 ! nucleoside salvage GO:0043174 11 7 0,000 2,361E-03 0,01031862 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 2,361E-03 0,01030019 ! male sex determination GO:0030238 15 7 0,000 2,361E-03 0,01028183 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 2,361E-03 0,01026353 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 2,361E-03 0,0102453 ! parturition GO:0007567 16 7 0,000 2,361E-03 0,01022714 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 2,361E-03 0,01020904 ! rRNA modification GO:0000154 14 7 0,000 2,361E-03 0,010191 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 2,361E-03 0,01017303 ! spindle checkpoint GO:0031577 16 7 0,000 2,361E-03 0,01015512 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 2,361E-03 0,01013727 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 2,361E-03 0,01011948 ! monocyte differentiation GO:0030224 16 7 0,000 2,361E-03 0,01010176 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 2,361E-03 0,0100841 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 2,361E-03 0,0100665 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 2,361E-03 0,01004897 ! hyaluronan metabolic process GO:0030212 9 7 0,000 2,361E-03 0,01003149 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 2,361E-03 0,01001407 ! anterograde axon cargo transport GO:0008089 18 7 0,000 2,361E-03 9,997E-03 ! fibrinolysis GO:0042730 11 7 0,000 2,361E-03 9,979E-03 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 2,361E-03 9,962E-03 ! skeletal muscle contraction GO:0003009 8 7 0,000 2,361E-03 9,945E-03 ! eating behavior GO:0042755 8 7 0,000 2,361E-03 9,928E-03 ! B cell lineage commitment GO:0002326 21 7 0,000 2,361E-03 9,911E-03 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 2,361E-03 9,894E-03 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 2,361E-03 9,877E-03 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 2,361E-03 9,86E-03 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 2,361E-03 9,843E-03 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 2,361E-03 9,826E-03 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 2,361E-03 9,81E-03 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 2,361E-03 9,793E-03 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 2,361E-03 9,776E-03 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 2,361E-03 9,76E-03 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 2,361E-03 9,743E-03 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 2,361E-03 9,727E-03 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 2,361E-03 9,711E-03 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 2,361E-03 9,694E-03 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 2,361E-03 9,678E-03 ! histone ubiquitination GO:0016574 9 7 0,000 2,361E-03 9,662E-03 ! regulation of meiosis GO:0040020 12 7 0,000 2,361E-03 9,646E-03 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 2,361E-03 9,63E-03 ! T cell lineage commitment GO:0002360 16 7 0,000 2,361E-03 9,614E-03 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 2,361E-03 9,598E-03 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 2,361E-03 9,582E-03 ! membrane to membrane docking GO:0022614 14 7 0,000 2,361E-03 9,566E-03 ! transcription termination GO:0006353 14 7 0,000 2,361E-03 9,55E-03 ! coenzyme A metabolic process GO:0015936 12 7 0,000 2,361E-03 9,534E-03 ! anaphase GO:0051322 18 7 0,000 2,361E-03 9,518E-03 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 2,361E-03 9,503E-03 ! axonal fasciculation GO:0007413 19 7 0,000 2,361E-03 9,487E-03 ! negative regulation of nuclear division GO:0051784 15 7 0,000 2,361E-03 9,471E-03 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 2,361E-03 9,456E-03 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 2,361E-03 9,44E-03 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 2,361E-03 9,425E-03 ! diuresis GO:0030146 12 7 0,000 2,361E-03 9,41E-03 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 2,361E-03 9,394E-03 ! thiamin metabolic process GO:0006772 7 7 0,000 2,361E-03 9,379E-03 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 2,361E-03 9,364E-03 ! antibiotic transport GO:0042891 9 7 0,000 2,361E-03 9,349E-03 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 2,361E-03 9,334E-03 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 2,361E-03 9,318E-03 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 2,361E-03 9,303E-03 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 2,361E-03 9,288E-03 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 2,361E-03 9,273E-03 ! melanin biosynthetic process GO:0042438 10 7 0,000 2,361E-03 9,259E-03 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 2,361E-03 9,244E-03 ! dopamine biosynthetic process GO:0042416 18 7 0,000 2,361E-03 9,229E-03 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 2,361E-03 9,214E-03 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 2,361E-03 9,2E-03 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 2,361E-03 9,185E-03 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 2,361E-03 9,17E-03 ! endosome to lysosome transport GO:0008333 12 7 0,000 2,361E-03 9,156E-03 ! protein modification by small protein removal GO:0070646 19 7 0,000 2,361E-03 9,141E-03 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 2,361E-03 9,127E-03 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 2,361E-03 9,112E-03 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 2,361E-03 9,098E-03 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 2,361E-03 9,084E-03 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 2,361E-03 9,069E-03 ! muscle adaptation GO:0043500 13 7 0,000 2,361E-03 9,055E-03 ! embryonic heart tube development GO:0035050 14 7 0,000 2,361E-03 9,041E-03 ! retina homeostasis GO:0001895 12 7 0,000 2,361E-03 9,027E-03 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 2,361E-03 9,013E-03 ! protein amino acid prenylation GO:0018346 19 7 0,000 2,361E-03 8,999E-03 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 2,361E-03 8,985E-03 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 2,361E-03 8,971E-03 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 2,698E-03 0,01023463 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 2,698E-03 0,01021876 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 2,698E-03 0,01020294 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 2,698E-03 0,01018717 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 2,698E-03 0,01017145 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 2,698E-03 0,01015578 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 2,698E-03 0,01014016 ! male meiosis GO:0007140 9 8 0,000 2,698E-03 0,01012458 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 2,698E-03 0,01010905 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 2,698E-03 0,01009357 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 2,698E-03 0,01007814 ! meiotic prophase I GO:0007128 14 8 0,000 2,698E-03 0,01006275 ! response to zinc ion GO:0010043 12 8 0,000 2,698E-03 0,01004741 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 2,698E-03 0,01003212 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 2,698E-03 0,01001687 ! oligopeptide transport GO:0006857 16 8 0,000 2,698E-03 0,01000167 ! actin-myosin filament sliding GO:0033275 13 8 0,000 2,698E-03 9,987E-03 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 2,698E-03 9,971E-03 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 2,698E-03 9,956E-03 ! signal peptide processing GO:0006465 12 8 0,000 2,698E-03 9,941E-03 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 2,698E-03 9,926E-03 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 2,698E-03 9,911E-03 ! macrophage chemotaxis GO:0048246 12 8 0,000 2,698E-03 9,897E-03 ! succinate metabolic process GO:0006105 17 8 0,000 2,698E-03 9,882E-03 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 2,698E-03 9,867E-03 ! membrane hyperpolarization GO:0060081 11 8 0,000 2,698E-03 9,852E-03 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 2,698E-03 9,837E-03 ! estrogen metabolic process GO:0008210 17 8 0,000 2,698E-03 9,823E-03 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 2,698E-03 9,808E-03 ! T-helper 1 type immune response GO:0042088 12 8 0,000 2,698E-03 9,794E-03 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 2,698E-03 9,779E-03 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 2,698E-03 9,765E-03 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 2,698E-03 9,75E-03 ! reflex GO:0060004 17 8 0,000 2,698E-03 9,736E-03 ! endothelial cell differentiation GO:0045446 17 8 0,000 2,698E-03 9,721E-03 ! glycerolipid catabolic process GO:0046503 14 8 0,000 2,698E-03 9,707E-03 ! hemoglobin metabolic process GO:0020027 14 8 0,000 2,698E-03 9,693E-03 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 2,698E-03 9,679E-03 ! pigment granule organization GO:0048753 17 8 0,000 2,698E-03 9,664E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 2,698E-03 9,65E-03 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 2,698E-03 9,636E-03 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 2,698E-03 9,622E-03 ! astrocyte differentiation GO:0048708 19 8 0,000 2,698E-03 9,608E-03 ! histidine catabolic process GO:0006548 10 8 0,000 2,698E-03 9,594E-03 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 2,698E-03 9,58E-03 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 2,698E-03 9,566E-03 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 2,698E-03 9,552E-03 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 2,698E-03 9,538E-03 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 2,698E-03 9,525E-03 ! regulation of pigmentation during development GO:0048070 25 8 0,000 2,698E-03 9,511E-03 ! melanin metabolic process GO:0006582 17 8 0,000 2,698E-03 9,497E-03 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 2,698E-03 9,484E-03 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 2,698E-03 9,47E-03 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 2,698E-03 9,456E-03 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 2,698E-03 9,443E-03 ! macrophage activation GO:0042116 13 8 0,000 2,698E-03 9,429E-03 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 2,698E-03 9,416E-03 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 2,698E-03 9,402E-03 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 2,698E-03 9,389E-03 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 2,698E-03 9,376E-03 ! purine salvage GO:0043101 12 8 0,000 2,698E-03 9,362E-03 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 2,698E-03 9,349E-03 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 2,698E-03 9,336E-03 ! osteoblast development GO:0002076 17 8 0,000 2,698E-03 9,323E-03 ! positive regulation of vasodilation GO:0045909 14 8 0,000 2,698E-03 9,309E-03 ! negative regulation of translational initiation GO:0045947 12 8 0,000 2,698E-03 9,296E-03 ! Schwann cell differentiation GO:0014037 21 8 0,000 2,698E-03 9,283E-03 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 2,698E-03 9,27E-03 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 2,698E-03 9,257E-03 ! response to UV-B GO:0010224 17 8 0,000 2,698E-03 9,244E-03 ! protein targeting to vacuole GO:0006623 14 8 0,000 2,698E-03 9,231E-03 ! protein retention in ER lumen GO:0006621 14 8 0,000 2,698E-03 9,218E-03 ! intermediate filament organization GO:0045109 12 8 0,000 2,698E-03 9,205E-03 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 2,698E-03 9,193E-03 ! cellular extravasation GO:0045123 13 8 0,000 2,698E-03 9,18E-03 ! cardiac muscle cell development GO:0055013 14 8 0,000 2,698E-03 9,167E-03 ! response to antibiotic GO:0046677 11 8 0,000 2,698E-03 9,154E-03 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 2,698E-03 9,142E-03 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 2,698E-03 9,129E-03 ! DNA topological change GO:0006265 12 8 0,000 2,698E-03 9,116E-03 ! response to tropane GO:0014073 15 8 0,000 2,698E-03 9,104E-03 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 2,698E-03 9,091E-03 ! melanosome transport GO:0032402 13 8 0,000 2,698E-03 9,079E-03 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 0,000 2,698E-03 9,066E-03 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 2,698E-03 9,054E-03 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 2,698E-03 9,041E-03 ! mast cell activation GO:0045576 14 8 0,000 2,698E-03 9,029E-03 ! multicellular organismal aging GO:0010259 20 8 0,000 2,698E-03 9,017E-03 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 2,698E-03 9,004E-03 ! gas homeostasis GO:0033483 14 8 0,000 2,698E-03 8,992E-03 ! dendrite morphogenesis GO:0048813 14 8 0,000 2,698E-03 8,98E-03 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 2,698E-03 8,967E-03 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 2,698E-03 8,955E-03 ! nucleosome disassembly GO:0006337 14 8 0,000 2,698E-03 8,943E-03 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 2,698E-03 8,931E-03 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 2,698E-03 8,919E-03 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 2,698E-03 8,907E-03 ! establishment of chromosome localization GO:0051303 14 8 0,000 2,698E-03 8,895E-03 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 2,698E-03 8,883E-03 ! intracellular lipid transport GO:0032365 16 8 0,000 2,698E-03 8,871E-03 ! response to tumor cell GO:0002347 16 8 0,000 2,698E-03 8,859E-03 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 2,698E-03 8,847E-03 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 2,698E-03 8,835E-03 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 2,698E-03 8,823E-03 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 2,698E-03 8,812E-03 ! positive regulation of epidermis development GO:0045684 13 8 0,000 2,698E-03 8,8E-03 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 2,698E-03 8,788E-03 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 2,698E-03 8,776E-03 ! hormone catabolic process GO:0042447 17 8 0,000 2,698E-03 8,765E-03 ! glycolipid catabolic process GO:0019377 16 8 0,000 2,698E-03 8,753E-03 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 2,698E-03 8,742E-03 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 2,698E-03 8,73E-03 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 2,698E-03 8,718E-03 ! positive regulation of glucose import GO:0046326 8 8 0,000 2,698E-03 8,707E-03 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 2,698E-03 8,695E-03 ! adult feeding behavior GO:0008343 10 8 0,000 2,698E-03 8,684E-03 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 2,698E-03 8,673E-03 ! ATP catabolic process GO:0006200 11 8 0,000 2,698E-03 8,661E-03 ! blastocyst growth GO:0001832 19 8 0,000 2,698E-03 8,65E-03 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 2,698E-03 8,638E-03 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 2,698E-03 8,627E-03 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 2,698E-03 8,616E-03 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 2,698E-03 8,605E-03 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 2,698E-03 8,593E-03 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 2,698E-03 8,582E-03 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 2,698E-03 8,571E-03 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 2,698E-03 8,56E-03 ! amino sugar catabolic process GO:0046348 11 8 0,000 2,698E-03 8,549E-03 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 2,698E-03 8,538E-03 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 2,698E-03 8,527E-03 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 2,698E-03 8,516E-03 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 2,698E-03 8,505E-03 ! behavioral response to nicotine GO:0035095 12 8 0,000 2,698E-03 8,494E-03 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 2,698E-03 8,483E-03 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 2,698E-03 8,472E-03 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 2,698E-03 8,461E-03 ! NAD biosynthetic process GO:0009435 17 8 0,000 2,698E-03 8,45E-03 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 2,698E-03 8,439E-03 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 2,698E-03 8,429E-03 ! axon extension GO:0048675 16 9 0,000 3,035E-03 9,469E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 3,035E-03 9,456E-03 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 3,035E-03 9,444E-03 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 3,035E-03 9,432E-03 ! pentose-phosphate shunt GO:0006098 16 9 0,000 3,035E-03 9,42E-03 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 3,035E-03 9,408E-03 ! cell proliferation in forebrain GO:0021846 18 9 0,000 3,035E-03 9,397E-03 ! neutral lipid catabolic process GO:0046461 14 9 0,000 3,035E-03 9,385E-03 ! reproductive behavior GO:0019098 22 9 0,000 3,035E-03 9,373E-03 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 3,035E-03 9,361E-03 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 3,035E-03 9,349E-03 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 3,035E-03 9,337E-03 ! UTP metabolic process GO:0046051 10 9 0,000 3,035E-03 9,326E-03 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 3,035E-03 9,314E-03 ! induction of positive chemotaxis GO:0050930 17 9 0,000 3,035E-03 9,302E-03 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 3,035E-03 9,291E-03 ! artery development GO:0060840 25 9 0,000 3,035E-03 9,279E-03 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 3,035E-03 9,267E-03 ! regulation of glycolysis GO:0006110 20 9 0,000 3,035E-03 9,256E-03 ! cerebral cortex cell migration GO:0021795 18 9 0,000 3,035E-03 9,244E-03 ! equilibrioception GO:0050957 20 9 0,000 3,035E-03 9,233E-03 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 3,035E-03 9,221E-03 ! chemosensory behavior GO:0007635 21 9 0,000 3,035E-03 9,21E-03 ! microtubule bundle formation GO:0001578 22 9 0,000 3,035E-03 9,198E-03 ! middle ear morphogenesis GO:0042474 14 9 0,000 3,035E-03 9,187E-03 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 3,035E-03 9,176E-03 ! leukocyte degranulation GO:0043299 16 9 0,000 3,035E-03 9,164E-03 ! ganglioside metabolic process GO:0001573 22 9 0,000 3,035E-03 9,153E-03 ! negative regulation of endocytosis GO:0045806 12 9 0,000 3,035E-03 9,142E-03 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 3,035E-03 9,13E-03 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 3,035E-03 9,119E-03 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 3,035E-03 9,108E-03 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 3,035E-03 9,097E-03 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 3,035E-03 9,086E-03 ! protein targeting to ER GO:0045047 25 9 0,000 3,035E-03 9,074E-03 ! ceramide biosynthetic process GO:0046513 20 9 0,000 3,035E-03 9,063E-03 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 3,035E-03 9,052E-03 ! T cell selection GO:0045058 27 9 0,000 3,035E-03 9,041E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 0,000 3,035E-03 9,03E-03 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 3,035E-03 9,019E-03 ! glycine catabolic process GO:0006546 15 9 0,000 3,035E-03 9,008E-03 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 3,035E-03 8,997E-03 ! endosome organization GO:0007032 20 9 0,000 3,035E-03 8,986E-03 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 3,035E-03 8,976E-03 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 3,035E-03 8,965E-03 ! regulation of type I interferon production GO:0032479 12 9 0,000 3,035E-03 8,954E-03 ! mannose metabolic process GO:0006013 13 9 0,000 3,035E-03 8,943E-03 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 3,035E-03 8,932E-03 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 3,035E-03 8,922E-03 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 3,035E-03 8,911E-03 ! Rac protein signal transduction GO:0016601 20 9 0,000 3,035E-03 8,9E-03 ! receptor clustering GO:0043113 20 9 0,000 3,035E-03 8,889E-03 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 3,035E-03 8,879E-03 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 3,035E-03 8,868E-03 ! retinol metabolic process GO:0042572 20 9 0,000 3,035E-03 8,858E-03 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 3,035E-03 8,847E-03 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 3,035E-03 8,837E-03 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 3,035E-03 8,826E-03 ! macrophage differentiation GO:0030225 15 9 0,000 3,035E-03 8,816E-03 ! oligodendrocyte development GO:0014003 11 9 0,000 3,035E-03 8,805E-03 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 3,035E-03 8,795E-03 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 3,035E-03 8,784E-03 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 3,035E-03 8,774E-03 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 3,035E-03 8,763E-03 ! response to amine stimulus GO:0014075 13 9 0,000 3,035E-03 8,753E-03 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 3,035E-03 8,743E-03 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 3,035E-03 8,732E-03 ! erythrocyte development GO:0048821 17 9 0,000 3,035E-03 8,722E-03 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 3,035E-03 8,712E-03 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 3,035E-03 8,702E-03 ! renal water homeostasis GO:0003091 15 9 0,000 3,035E-03 8,691E-03 ! postreplication repair GO:0006301 25 9 0,000 3,035E-03 8,681E-03 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 3,035E-03 8,671E-03 ! cerebellum morphogenesis GO:0021587 14 9 0,000 3,035E-03 8,661E-03 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 3,035E-03 8,651E-03 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 3,035E-03 8,641E-03 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 3,035E-03 8,631E-03 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 3,035E-03 8,621E-03 ! sterol catabolic process GO:0016127 14 9 0,000 3,035E-03 8,611E-03 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 3,035E-03 8,601E-03 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 3,035E-03 8,591E-03 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 3,035E-03 8,581E-03 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 3,035E-03 8,571E-03 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 3,035E-03 8,561E-03 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 3,035E-03 8,551E-03 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 3,035E-03 8,541E-03 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 3,035E-03 8,531E-03 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 3,035E-03 8,522E-03 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 3,035E-03 8,512E-03 ! regulation of synaptogenesis GO:0051963 15 9 0,000 3,035E-03 8,502E-03 ! purine base metabolic process GO:0006144 25 9 0,000 3,035E-03 8,492E-03 ! pigment granule transport GO:0051904 17 9 0,000 3,035E-03 8,483E-03 ! regulation of telomere maintenance GO:0032204 17 9 0,000 3,035E-03 8,473E-03 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 3,035E-03 8,463E-03 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 3,035E-03 8,454E-03 ! regulation of muscle adaptation GO:0043502 14 9 0,000 3,035E-03 8,444E-03 ! regulation of amino acid transport GO:0051955 12 9 0,000 3,035E-03 8,434E-03 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 3,035E-03 8,425E-03 ! mitochondrion localization GO:0051646 18 9 0,000 3,035E-03 8,415E-03 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 3,371E-03 9,338E-03 ! regulation of developmental growth GO:0048638 16 10 0,000 3,371E-03 9,328E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 0,000 3,371E-03 9,317E-03 ! autophagic vacuole formation GO:0000045 17 10 0,000 3,371E-03 9,307E-03 ! negative regulation of blood pressure GO:0045776 26 10 0,000 3,371E-03 9,296E-03 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 3,371E-03 9,286E-03 ! associative learning GO:0008306 21 10 0,000 3,371E-03 9,275E-03 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 3,371E-03 9,265E-03 ! regulation of phosphatase activity GO:0010921 28 10 0,000 3,371E-03 9,254E-03 ! phosphate transport GO:0006817 24 10 0,000 3,371E-03 9,244E-03 ! cell volume homeostasis GO:0006884 17 10 0,000 3,371E-03 9,234E-03 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 3,371E-03 9,223E-03 ! CTP metabolic process GO:0046036 11 10 0,000 3,371E-03 9,213E-03 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 3,371E-03 9,203E-03 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 3,371E-03 9,192E-03 ! GTP metabolic process GO:0046039 11 10 0,000 3,371E-03 9,182E-03 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 3,371E-03 9,172E-03 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 3,371E-03 9,162E-03 ! social behavior GO:0035176 29 10 0,000 3,371E-03 9,151E-03 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 3,371E-03 9,141E-03 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 3,371E-03 9,131E-03 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 3,371E-03 9,121E-03 ! androgen metabolic process GO:0008209 17 10 0,000 3,371E-03 9,111E-03 ! phospholipid efflux GO:0033700 19 10 0,000 3,371E-03 9,101E-03 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 3,371E-03 9,091E-03 ! bile acid and bile salt transport GO:0015721 15 10 0,000 3,371E-03 9,081E-03 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 3,371E-03 9,071E-03 ! positive regulation of heart contraction GO:0045823 17 10 0,000 3,371E-03 9,061E-03 ! lung alveolus development GO:0048286 26 10 0,000 3,371E-03 9,051E-03 ! pathogenesis GO:0009405 17 10 0,000 3,371E-03 9,041E-03 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 3,371E-03 9,031E-03 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 3,371E-03 9,021E-03 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 3,371E-03 9,011E-03 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 3,371E-03 9,001E-03 ! endoderm development GO:0007492 18 10 0,000 3,371E-03 8,992E-03 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 3,371E-03 8,982E-03 ! arginine catabolic process GO:0006527 17 10 0,000 3,371E-03 8,972E-03 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 3,371E-03 8,962E-03 ! proline metabolic process GO:0006560 13 10 0,000 3,371E-03 8,953E-03 ! glucan biosynthetic process GO:0009250 14 10 0,000 3,371E-03 8,943E-03 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 3,371E-03 8,933E-03 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 3,371E-03 8,923E-03 ! V(D)J recombination GO:0033151 34 10 0,000 3,371E-03 8,914E-03 ! reverse cholesterol transport GO:0043691 19 10 0,000 3,371E-03 8,904E-03 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 3,371E-03 8,895E-03 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 3,371E-03 8,885E-03 ! B cell proliferation GO:0042100 19 10 0,000 3,371E-03 8,875E-03 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 3,371E-03 8,866E-03 ! regulation of sodium ion transport GO:0002028 26 10 0,000 3,371E-03 8,856E-03 ! multicellular organism growth GO:0035264 19 10 0,000 3,371E-03 8,847E-03 ! phagocytosis, engulfment GO:0006911 33 10 0,000 3,371E-03 8,837E-03 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 3,371E-03 8,828E-03 ! ruffle organization GO:0031529 17 10 0,000 3,371E-03 8,818E-03 ! epithelial cell development GO:0002064 21 10 0,000 3,371E-03 8,809E-03 ! lens development in camera-type eye GO:0002088 17 10 0,000 3,371E-03 8,799E-03 ! retinoic acid metabolic process GO:0042573 14 10 0,000 3,371E-03 8,79E-03 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 3,371E-03 8,781E-03 ! positive regulation of translational initiation GO:0045948 12 10 0,000 3,371E-03 8,771E-03 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 3,371E-03 8,762E-03 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 3,371E-03 8,753E-03 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 3,371E-03 8,743E-03 ! motor axon guidance GO:0008045 22 10 0,000 3,371E-03 8,734E-03 ! copper ion homeostasis GO:0055070 13 10 0,000 3,371E-03 8,725E-03 ! regulation of bone resorption GO:0045124 25 10 0,000 3,371E-03 8,716E-03 ! protein heterooligomerization GO:0051291 17 10 0,000 3,371E-03 8,706E-03 ! regulation of gliogenesis GO:0014013 23 10 0,000 3,371E-03 8,697E-03 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 3,371E-03 8,688E-03 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 3,371E-03 8,679E-03 ! segment specification GO:0007379 15 10 0,000 3,371E-03 8,67E-03 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 3,371E-03 8,661E-03 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 3,371E-03 8,652E-03 ! blastoderm segmentation GO:0007350 19 10 0,000 3,371E-03 8,643E-03 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 3,371E-03 8,633E-03 ! response to dsRNA GO:0043331 23 10 0,000 3,371E-03 8,624E-03 ! DNA ligation GO:0006266 18 10 0,000 3,371E-03 8,615E-03 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 3,371E-03 8,606E-03 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 3,371E-03 8,597E-03 ! melanosome localization GO:0032400 16 10 0,000 3,371E-03 8,588E-03 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 3,371E-03 8,58E-03 ! regulation of B cell differentiation GO:0045577 24 10 0,000 3,371E-03 8,571E-03 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 3,371E-03 8,562E-03 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 3,371E-03 8,553E-03 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 3,371E-03 8,544E-03 ! induction of an organ GO:0001759 17 10 0,000 3,371E-03 8,535E-03 ! leukocyte activation during immune response GO:0002366 15 10 0,000 3,371E-03 8,526E-03 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 3,371E-03 8,517E-03 ! protein sumoylation GO:0016925 17 10 0,000 3,371E-03 8,509E-03 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 3,371E-03 8,5E-03 ! hindbrain morphogenesis GO:0021575 19 10 0,000 3,371E-03 8,491E-03 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 3,371E-03 8,482E-03 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 3,371E-03 8,474E-03 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 3,371E-03 8,465E-03 ! salivary gland development GO:0007431 28 10 0,000 3,371E-03 8,456E-03 ! ubiquinone metabolic process GO:0006743 17 10 0,000 3,371E-03 8,448E-03 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 3,371E-03 8,439E-03 ! midbrain development GO:0030901 14 10 0,000 3,371E-03 8,43E-03 ! musculoskeletal movement GO:0050881 16 10 0,000 3,371E-03 8,422E-03 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 3,371E-03 8,413E-03 ! methionine biosynthetic process GO:0009086 21 10 0,000 3,371E-03 8,404E-03 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 3,371E-03 8,396E-03 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 3,371E-03 8,387E-03 ! quaternary ammonium group transport GO:0015697 22 10 0,000 3,371E-03 8,379E-03 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 3,371E-03 8,37E-03 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 3,371E-03 8,362E-03 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 3,371E-03 8,353E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 3,371E-03 8,345E-03 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 3,371E-03 8,336E-03 ! establishment of pigment granule localization GO:0051905 18 10 0,000 3,371E-03 8,328E-03 ! blastocyst formation GO:0001825 18 10 0,000 3,371E-03 8,32E-03 ! regulation of fibrinolysis GO:0051917 20 10 0,000 3,371E-03 8,311E-03 ! cerebellar cortex development GO:0021695 16 10 0,000 3,371E-03 8,303E-03 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 3,371E-03 8,294E-03 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 3,371E-03 8,286E-03 ! response to nicotine GO:0035094 20 10 0,000 3,371E-03 8,278E-03 ! negative regulation of immune effector process GO:0002698 23 10 0,000 3,371E-03 8,269E-03 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 3,371E-03 8,261E-03 ! negative regulation of muscle development GO:0048635 27 11 0,000 3,708E-03 9,077E-03 ! respiratory burst GO:0045730 17 11 0,000 3,708E-03 9,068E-03 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 3,708E-03 9,059E-03 ! neuron fate specification GO:0048665 18 11 0,000 3,708E-03 9,05E-03 ! telencephalon cell migration GO:0022029 23 11 0,000 3,708E-03 9,04E-03 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 3,708E-03 9,031E-03 ! thyroid gland development GO:0030878 26 11 0,000 3,708E-03 9,022E-03 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 3,708E-03 9,013E-03 ! synapsis GO:0007129 14 11 0,000 3,708E-03 9,005E-03 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 3,708E-03 8,996E-03 ! Golgi vesicle budding GO:0048194 26 11 0,000 3,708E-03 8,987E-03 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 3,708E-03 8,978E-03 ! response to pain GO:0048265 27 11 0,000 3,708E-03 8,969E-03 ! detection of mechanical stimulus GO:0050982 22 11 0,000 3,708E-03 8,96E-03 ! keratinocyte proliferation GO:0043616 19 11 0,000 3,708E-03 8,951E-03 ! blood vessel remodeling GO:0001974 30 11 0,000 3,708E-03 8,942E-03 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 3,708E-03 8,933E-03 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 3,708E-03 8,925E-03 ! bone resorption GO:0045453 16 11 0,000 3,708E-03 8,916E-03 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 3,708E-03 8,907E-03 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 3,708E-03 8,898E-03 ! negative regulation of proteolysis GO:0045861 25 11 0,000 3,708E-03 8,89E-03 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 3,708E-03 8,881E-03 ! melanocyte differentiation GO:0030318 20 11 0,000 3,708E-03 8,872E-03 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 3,708E-03 8,864E-03 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 3,708E-03 8,855E-03 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 3,708E-03 8,846E-03 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 3,708E-03 8,838E-03 ! regulation of intracellular pH GO:0051453 21 11 0,000 3,708E-03 8,829E-03 ! substrate-bound cell migration GO:0006929 14 11 0,000 3,708E-03 8,82E-03 ! UV protection GO:0009650 20 11 0,000 3,708E-03 8,812E-03 ! adult heart development GO:0007512 16 11 0,000 3,708E-03 8,803E-03 ! chondrocyte differentiation GO:0002062 27 11 0,000 3,708E-03 8,795E-03 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 3,708E-03 8,786E-03 ! macroautophagy GO:0016236 19 11 0,000 3,708E-03 8,778E-03 ! temperature homeostasis GO:0001659 18 11 0,000 3,708E-03 8,769E-03 ! behavioral fear response GO:0001662 27 11 0,000 3,708E-03 8,761E-03 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 3,708E-03 8,752E-03 ! negative regulation of ossification GO:0030279 27 11 0,000 3,708E-03 8,744E-03 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 3,708E-03 8,735E-03 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 3,708E-03 8,727E-03 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 3,708E-03 8,719E-03 ! alpha-beta T cell activation GO:0046631 26 11 0,000 3,708E-03 8,71E-03 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 3,708E-03 8,702E-03 ! regulation of organ growth GO:0046620 14 11 0,000 3,708E-03 8,693E-03 ! pigment granule localization GO:0051875 20 11 0,000 3,708E-03 8,685E-03 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 3,708E-03 8,677E-03 ! vasoconstriction GO:0042310 20 11 0,000 3,708E-03 8,668E-03 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 3,708E-03 8,66E-03 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 3,708E-03 8,652E-03 ! embryonic axis specification GO:0000578 19 11 0,000 3,708E-03 8,644E-03 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 3,708E-03 8,635E-03 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 3,708E-03 8,627E-03 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 3,708E-03 8,619E-03 ! nitric oxide metabolic process GO:0046209 17 11 0,000 3,708E-03 8,611E-03 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 3,708E-03 8,603E-03 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 3,708E-03 8,594E-03 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 3,708E-03 8,586E-03 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 3,708E-03 8,578E-03 ! prophase GO:0051324 17 11 0,000 3,708E-03 8,57E-03 ! neuroblast proliferation GO:0007405 25 11 0,000 3,708E-03 8,562E-03 ! nucleosome positioning GO:0016584 15 11 0,000 3,708E-03 8,554E-03 ! regulation of isotype switching GO:0045191 24 11 0,000 3,708E-03 8,546E-03 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 3,708E-03 8,538E-03 ! negative regulation of neurological system process GO:0031645 21 11 0,000 3,708E-03 8,53E-03 ! apical protein localization GO:0045176 18 11 0,000 3,708E-03 8,522E-03 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 3,708E-03 8,514E-03 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 3,708E-03 8,506E-03 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 3,708E-03 8,498E-03 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 3,708E-03 8,49E-03 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 3,708E-03 8,482E-03 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 3,708E-03 8,474E-03 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 21 11 0,000 3,708E-03 8,466E-03 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 3,708E-03 8,458E-03 ! oocyte development GO:0048599 20 11 0,000 3,708E-03 8,45E-03 ! negative regulation of glucose import GO:0046325 18 11 0,000 3,708E-03 8,442E-03 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 3,708E-03 8,434E-03 ! embryonic gut development GO:0048566 19 11 0,000 3,708E-03 8,427E-03 ! regulation of organic acid transport GO:0032890 19 11 0,000 3,708E-03 8,419E-03 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 3,708E-03 8,411E-03 ! activation of innate immune response GO:0002218 16 11 0,000 3,708E-03 8,403E-03 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 3,708E-03 8,395E-03 ! cardiac cell differentiation GO:0035051 36 11 0,000 3,708E-03 8,388E-03 ! lysogeny GO:0030069 22 11 0,000 3,708E-03 8,38E-03 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 3,708E-03 8,372E-03 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 3,708E-03 8,364E-03 ! sequestering of metal ion GO:0051238 15 11 0,000 3,708E-03 8,357E-03 ! regulation of embryonic development GO:0045995 35 11 0,000 3,708E-03 8,349E-03 ! nucleus localization GO:0051647 22 11 0,000 3,708E-03 8,341E-03 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 4,044E-03 9,09E-03 ! positive regulation of blood pressure GO:0045777 18 12 0,000 4,044E-03 9,081E-03 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 4,044E-03 9,073E-03 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 4,044E-03 9,065E-03 ! virus-host interaction GO:0019048 30 12 0,000 4,044E-03 9,056E-03 ! regulation of B cell proliferation GO:0030888 22 12 0,000 4,044E-03 9,048E-03 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 4,044E-03 9,04E-03 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 4,044E-03 9,032E-03 ! protein complex disassembly GO:0043241 28 12 0,000 4,044E-03 9,023E-03 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 4,044E-03 9,015E-03 ! regulation of cell projection assembly GO:0060491 33 12 0,000 4,044E-03 9,007E-03 ! hippocampus development GO:0021766 29 12 0,000 4,044E-03 8,999E-03 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 4,044E-03 8,99E-03 ! cytokine biosynthetic process GO:0042089 23 12 0,000 4,044E-03 8,982E-03 ! T cell proliferation GO:0042098 32 12 0,000 4,044E-03 8,974E-03 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 4,044E-03 8,966E-03 ! regulation of exit from mitosis GO:0007096 19 12 0,000 4,044E-03 8,958E-03 ! ventral spinal cord development GO:0021517 25 12 0,000 4,044E-03 8,95E-03 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 4,044E-03 8,942E-03 ! drug transport GO:0015893 16 12 0,000 4,044E-03 8,934E-03 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 4,044E-03 8,926E-03 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 4,044E-03 8,917E-03 ! tyrosine metabolic process GO:0006570 19 12 0,000 4,044E-03 8,909E-03 ! polyamine metabolic process GO:0006595 18 12 0,000 4,044E-03 8,901E-03 ! focal adhesion formation GO:0048041 37 12 0,000 4,044E-03 8,893E-03 ! mitotic spindle organization GO:0007052 23 12 0,000 4,044E-03 8,885E-03 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 4,044E-03 8,877E-03 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 4,044E-03 8,869E-03 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 4,044E-03 8,861E-03 ! lipid digestion GO:0044241 21 12 0,000 4,044E-03 8,854E-03 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 4,044E-03 8,846E-03 ! entry into host cell GO:0030260 34 12 0,000 4,044E-03 8,838E-03 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 4,044E-03 8,83E-03 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 4,044E-03 8,822E-03 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 4,044E-03 8,814E-03 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 4,044E-03 8,806E-03 ! protein targeting to peroxisome GO:0006625 27 12 0,000 4,044E-03 8,798E-03 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 4,044E-03 8,791E-03 ! regulation of phagocytosis GO:0050764 17 12 0,000 4,044E-03 8,783E-03 ! snRNA metabolic process GO:0016073 30 12 0,000 4,044E-03 8,775E-03 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 4,044E-03 8,767E-03 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 4,044E-03 8,759E-03 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 4,044E-03 8,752E-03 ! cranial nerve development GO:0021545 23 12 0,000 4,044E-03 8,744E-03 ! fucose catabolic process GO:0019317 25 12 0,000 4,044E-03 8,736E-03 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 4,044E-03 8,728E-03 ! histone acetylation GO:0016573 27 12 0,000 4,044E-03 8,721E-03 ! mRNA polyadenylation GO:0006378 24 12 0,000 4,044E-03 8,713E-03 ! autonomic nervous system development GO:0048483 24 12 0,000 4,044E-03 8,705E-03 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 4,044E-03 8,698E-03 ! zymogen activation GO:0031638 18 12 0,000 4,044E-03 8,69E-03 ! peptidyl-lysine modification GO:0018205 21 12 0,000 4,044E-03 8,682E-03 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 4,044E-03 8,675E-03 ! glutathione biosynthetic process GO:0006750 15 12 0,000 4,044E-03 8,667E-03 ! regulation of leukocyte migration GO:0002685 29 12 0,000 4,044E-03 8,66E-03 ! oocyte differentiation GO:0009994 21 12 0,000 4,044E-03 8,652E-03 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 4,044E-03 8,644E-03 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 4,044E-03 8,637E-03 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 4,044E-03 8,629E-03 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 4,044E-03 8,622E-03 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 4,044E-03 8,614E-03 ! defense response to fungus GO:0050832 15 12 0,000 4,044E-03 8,607E-03 ! developmental induction GO:0031128 22 12 0,000 4,044E-03 8,599E-03 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 4,044E-03 8,592E-03 ! lamellipodium assembly GO:0030032 24 12 0,000 4,044E-03 8,584E-03 ! response to cold GO:0009409 17 12 0,000 4,044E-03 8,577E-03 ! establishment of cell polarity GO:0030010 21 12 0,000 4,044E-03 8,569E-03 ! regulation of synapse organization GO:0050807 18 12 0,000 4,044E-03 8,562E-03 ! localization within membrane GO:0051668 26 12 0,000 4,044E-03 8,555E-03 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 4,381E-03 9,258E-03 ! cGMP metabolic process GO:0046068 18 13 0,000 4,381E-03 9,25E-03 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 4,381E-03 9,242E-03 ! regulation of chemokine production GO:0032642 18 13 0,000 4,381E-03 9,234E-03 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 4,381E-03 9,226E-03 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 4,381E-03 9,218E-03 ! peroxisomal transport GO:0043574 28 13 0,000 4,381E-03 9,21E-03 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 4,381E-03 9,202E-03 ! cartilage condensation GO:0001502 22 13 0,000 4,381E-03 9,194E-03 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 4,381E-03 9,186E-03 ! organelle fusion GO:0048284 36 13 0,000 4,381E-03 9,179E-03 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 4,381E-03 9,171E-03 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 4,381E-03 9,163E-03 ! pseudouridine synthesis GO:0001522 19 13 0,000 4,381E-03 9,155E-03 ! endocrine pancreas development GO:0031018 25 13 0,000 4,381E-03 9,147E-03 ! positive regulation of cell growth GO:0030307 24 13 0,000 4,381E-03 9,139E-03 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 4,381E-03 9,132E-03 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 4,381E-03 9,124E-03 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 4,381E-03 9,116E-03 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 4,381E-03 9,108E-03 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 4,381E-03 9,101E-03 ! methionine metabolic process GO:0006555 31 13 0,000 4,381E-03 9,093E-03 ! plasma membrane organization GO:0007009 27 13 0,000 4,381E-03 9,085E-03 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 4,381E-03 9,077E-03 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 4,381E-03 9,07E-03 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 4,381E-03 9,062E-03 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 4,381E-03 9,054E-03 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 4,381E-03 9,047E-03 ! cytokine metabolic process GO:0042107 24 13 0,000 4,381E-03 9,039E-03 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 4,381E-03 9,031E-03 ! exocrine system development GO:0035272 34 13 0,000 4,381E-03 9,024E-03 ! asymmetric protein localization GO:0008105 24 13 0,000 4,381E-03 9,016E-03 ! membrane protein proteolysis GO:0033619 33 13 0,000 4,381E-03 9,009E-03 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 4,381E-03 9,001E-03 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 4,381E-03 8,993E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 4,381E-03 8,986E-03 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 4,381E-03 8,978E-03 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 4,381E-03 8,971E-03 ! protein homotetramerization GO:0051289 24 13 0,000 4,381E-03 8,963E-03 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 4,381E-03 8,956E-03 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 4,381E-03 8,948E-03 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 4,381E-03 8,941E-03 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 4,381E-03 8,933E-03 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 4,381E-03 8,926E-03 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 4,381E-03 8,919E-03 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 4,381E-03 8,911E-03 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 4,381E-03 8,904E-03 ! histone methylation GO:0016571 29 13 0,000 4,381E-03 8,896E-03 ! chromatin silencing GO:0006342 29 13 0,000 4,381E-03 8,889E-03 ! gland morphogenesis GO:0022612 31 13 0,000 4,381E-03 8,882E-03 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 4,381E-03 8,874E-03 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 4,381E-03 8,867E-03 ! regulation of epidermis development GO:0045682 19 13 0,000 4,381E-03 8,859E-03 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 4,381E-03 8,852E-03 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 4,381E-03 8,845E-03 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 4,381E-03 8,838E-03 ! spleen development GO:0048536 24 13 0,000 4,381E-03 8,83E-03 ! regulation of mRNA stability GO:0043488 32 13 0,000 4,381E-03 8,823E-03 ! digestive tract morphogenesis GO:0048546 31 13 0,000 4,381E-03 8,816E-03 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 4,381E-03 8,808E-03 ! anterior/posterior axis specification GO:0009948 22 13 0,000 4,381E-03 8,801E-03 ! regulation of RNA splicing GO:0043484 22 13 0,000 4,381E-03 8,794E-03 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 4,381E-03 8,787E-03 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 4,381E-03 8,78E-03 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 4,381E-03 8,772E-03 ! mRNA 3'-end processing GO:0031124 25 13 0,000 4,381E-03 8,765E-03 ! insulin secretion GO:0030073 24 13 0,000 4,381E-03 8,758E-03 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 4,381E-03 8,751E-03 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 4,381E-03 8,744E-03 ! acrosome reaction GO:0007340 19 13 0,000 4,381E-03 8,737E-03 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 4,381E-03 8,729E-03 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 4,381E-03 8,722E-03 ! rRNA transcription GO:0009303 28 14 0,000 4,717E-03 9,384E-03 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 4,717E-03 9,377E-03 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 4,717E-03 9,369E-03 ! water transport GO:0006833 21 14 0,000 4,717E-03 9,361E-03 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 4,717E-03 9,354E-03 ! non-recombinational repair GO:0000726 29 14 0,000 4,717E-03 9,346E-03 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 4,717E-03 9,339E-03 ! retina development in camera-type eye GO:0060041 28 14 0,000 4,717E-03 9,331E-03 ! hair follicle morphogenesis GO:0031069 27 14 0,000 4,717E-03 9,323E-03 ! RNA polyadenylation GO:0043631 32 14 0,000 4,717E-03 9,316E-03 ! lipid localization GO:0010876 32 14 0,000 4,717E-03 9,308E-03 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 4,717E-03 9,301E-03 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 4,717E-03 9,293E-03 ! regulated secretory pathway GO:0045055 24 14 0,000 4,717E-03 9,286E-03 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 4,717E-03 9,278E-03 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 4,717E-03 9,271E-03 ! arginine metabolic process GO:0006525 21 14 0,000 4,717E-03 9,263E-03 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 4,717E-03 9,256E-03 ! cell-cell junction assembly GO:0007043 32 14 0,000 4,717E-03 9,249E-03 ! regulation of heart rate GO:0002027 25 14 0,000 4,717E-03 9,241E-03 ! fear response GO:0042596 34 14 0,000 4,717E-03 9,234E-03 ! organic alcohol transport GO:0015850 29 14 0,000 4,717E-03 9,226E-03 ! negative regulation of caspase activity GO:0043154 23 14 0,000 4,717E-03 9,219E-03 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 4,717E-03 9,212E-03 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 4,717E-03 9,204E-03 ! neutral amino acid transport GO:0015804 28 14 0,000 4,717E-03 9,197E-03 ! bone mineralization GO:0030282 18 14 0,000 4,717E-03 9,19E-03 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 4,717E-03 9,182E-03 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 4,717E-03 9,175E-03 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 4,717E-03 9,168E-03 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 4,717E-03 9,16E-03 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 4,717E-03 9,153E-03 ! regulation of cellular pH GO:0030641 27 14 0,000 4,717E-03 9,146E-03 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 4,717E-03 9,139E-03 ! ribosome assembly GO:0042255 18 14 0,000 4,717E-03 9,131E-03 ! cerebellum development GO:0021549 23 14 0,000 4,717E-03 9,124E-03 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 4,717E-03 9,117E-03 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 4,717E-03 9,11E-03 ! negative regulation of protein secretion GO:0050709 30 14 0,000 4,717E-03 9,102E-03 ! response to gamma radiation GO:0010332 30 14 0,000 4,717E-03 9,095E-03 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 4,717E-03 9,088E-03 ! NADP metabolic process GO:0006739 24 14 0,000 4,717E-03 9,081E-03 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 4,717E-03 9,074E-03 ! oxygen transport GO:0015671 22 14 0,000 4,717E-03 9,067E-03 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 4,717E-03 9,06E-03 ! male genitalia development GO:0030539 26 14 0,000 4,717E-03 9,052E-03 ! regulation of RNA stability GO:0043487 33 14 0,000 4,717E-03 9,045E-03 ! regulation of axon extension GO:0030516 43 14 0,000 4,717E-03 9,038E-03 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 4,717E-03 9,031E-03 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 4,717E-03 9,024E-03 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 4,717E-03 9,017E-03 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 5,053E-03 9,652E-03 ! lactation GO:0007595 30 15 0,000 5,053E-03 9,644E-03 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 5,053E-03 9,637E-03 ! reproductive cellular process GO:0048610 22 15 0,000 5,053E-03 9,629E-03 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 5,053E-03 9,622E-03 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 5,053E-03 9,614E-03 ! superoxide anion generation GO:0042554 22 15 0,000 5,053E-03 9,607E-03 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 5,053E-03 9,599E-03 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 5,053E-03 9,592E-03 ! phospholipid catabolic process GO:0009395 27 15 0,000 5,053E-03 9,585E-03 ! copper ion transport GO:0006825 22 15 0,000 5,053E-03 9,577E-03 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 5,053E-03 9,57E-03 ! cardiac muscle contraction GO:0060048 28 15 0,000 5,053E-03 9,562E-03 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 5,053E-03 9,555E-03 ! sulfate transport GO:0008272 27 15 0,000 5,053E-03 9,548E-03 ! response to cAMP GO:0051591 25 15 0,000 5,053E-03 9,54E-03 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 5,053E-03 9,533E-03 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 5,053E-03 9,525E-03 ! regulation of mRNA processing GO:0050684 26 15 0,000 5,053E-03 9,518E-03 ! response to hexose stimulus GO:0009746 25 15 0,000 5,053E-03 9,511E-03 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 5,053E-03 9,503E-03 ! glycoprotein catabolic process GO:0006516 33 15 0,000 5,053E-03 9,496E-03 ! vesicle coating GO:0006901 38 15 0,000 5,053E-03 9,489E-03 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 5,053E-03 9,482E-03 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 5,053E-03 9,474E-03 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 5,053E-03 9,467E-03 ! regulation of exocytosis GO:0017157 26 15 0,000 5,053E-03 9,46E-03 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 5,053E-03 9,452E-03 ! G1/S transition checkpoint GO:0031575 37 15 0,000 5,053E-03 9,445E-03 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 5,053E-03 9,438E-03 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 5,053E-03 9,431E-03 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 5,053E-03 9,424E-03 ! regulation of vasodilation GO:0042312 27 15 0,000 5,053E-03 9,416E-03 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 5,053E-03 9,409E-03 ! histone deacetylation GO:0016575 24 15 0,000 5,053E-03 9,402E-03 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 5,053E-03 9,395E-03 ! water homeostasis GO:0030104 28 15 0,000 5,053E-03 9,388E-03 ! cofactor transport GO:0051181 30 15 0,000 5,053E-03 9,381E-03 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 5,053E-03 9,374E-03 ! muscle maintenance GO:0046716 26 15 0,000 5,053E-03 9,366E-03 ! protein-chromophore linkage GO:0018298 25 15 0,000 5,053E-03 9,359E-03 ! intestinal absorption GO:0050892 31 15 0,000 5,053E-03 9,352E-03 ! dopamine metabolic process GO:0042417 35 15 0,000 5,053E-03 9,345E-03 ! cAMP biosynthetic process GO:0006171 25 15 0,000 5,053E-03 9,338E-03 ! heme biosynthetic process GO:0006783 33 15 0,000 5,053E-03 9,331E-03 ! cell killing GO:0001906 32 15 0,000 5,053E-03 9,324E-03 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 5,053E-03 9,317E-03 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 5,053E-03 9,31E-03 ! L-fucose metabolic process GO:0042354 33 15 0,000 5,053E-03 9,303E-03 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 5,053E-03 9,296E-03 ! actin filament polymerization GO:0030041 27 15 0,000 5,053E-03 9,289E-03 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 5,053E-03 9,282E-03 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 5,389E-03 9,892E-03 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 5,389E-03 9,884E-03 ! positive regulation of cell size GO:0045793 29 16 0,000 5,389E-03 9,877E-03 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 5,389E-03 9,869E-03 ! dicarboxylic acid transport GO:0006835 47 16 0,000 5,389E-03 9,862E-03 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 5,389E-03 9,855E-03 ! bone remodeling GO:0046849 28 16 0,000 5,389E-03 9,847E-03 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 5,389E-03 9,84E-03 ! heterophilic cell adhesion GO:0007157 43 16 0,000 5,389E-03 9,833E-03 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 5,389E-03 9,825E-03 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 5,389E-03 9,818E-03 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 5,389E-03 9,811E-03 ! positive regulation of ion transport GO:0043270 23 16 0,000 5,389E-03 9,803E-03 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 5,389E-03 9,796E-03 ! startle response GO:0001964 28 16 0,000 5,389E-03 9,789E-03 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 5,389E-03 9,781E-03 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 5,389E-03 9,774E-03 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 5,389E-03 9,767E-03 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 5,389E-03 9,76E-03 ! protein polyubiquitination GO:0000209 41 16 0,000 5,389E-03 9,753E-03 ! glutamate metabolic process GO:0006536 25 16 0,000 5,389E-03 9,745E-03 ! pituitary gland development GO:0021983 30 16 0,000 5,389E-03 9,738E-03 ! response to osmotic stress GO:0006970 27 16 0,000 5,389E-03 9,731E-03 ! lysosomal transport GO:0007041 31 16 0,000 5,389E-03 9,724E-03 ! fructose metabolic process GO:0006000 25 16 0,000 5,389E-03 9,717E-03 ! L-amino acid transport GO:0015807 33 16 0,000 5,389E-03 9,709E-03 ! stem cell development GO:0048864 46 16 0,000 5,389E-03 9,702E-03 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 5,389E-03 9,695E-03 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 5,389E-03 9,688E-03 ! intermediate filament-based process GO:0045103 36 16 0,000 5,389E-03 9,681E-03 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 5,389E-03 9,674E-03 ! negative regulation of immune response GO:0050777 38 16 0,000 5,389E-03 9,667E-03 ! axon cargo transport GO:0008088 46 16 0,000 5,389E-03 9,659E-03 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 5,389E-03 9,652E-03 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 5,389E-03 9,645E-03 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 5,389E-03 9,638E-03 ! DNA replication initiation GO:0006270 28 16 0,000 5,389E-03 9,631E-03 ! neuron recognition GO:0008038 40 16 0,000 5,389E-03 9,624E-03 ! mRNA splice site selection GO:0006376 44 16 0,000 5,389E-03 9,617E-03 ! tissue regeneration GO:0042246 27 16 0,000 5,389E-03 9,61E-03 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 5,389E-03 9,603E-03 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 5,389E-03 9,596E-03 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 5,389E-03 9,589E-03 ! biomineral formation GO:0031214 22 16 0,000 5,389E-03 9,582E-03 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 5,389E-03 9,575E-03 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 5,389E-03 9,568E-03 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 5,389E-03 9,561E-03 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 5,389E-03 9,554E-03 ! regulation of ATPase activity GO:0043462 26 16 0,000 5,389E-03 9,547E-03 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 5,389E-03 9,541E-03 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 5,389E-03 9,534E-03 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 5,389E-03 9,527E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 5,389E-03 9,52E-03 ! peptide hormone processing GO:0016486 27 16 0,000 5,389E-03 9,513E-03 ! positive regulation of cell killing GO:0031343 36 17 0,000 5,725E-03 0,01009863 ! metencephalon development GO:0022037 32 17 0,000 5,725E-03 0,01009134 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 5,725E-03 0,01008407 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 5,725E-03 0,0100768 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 5,725E-03 0,01006955 ! signal complex assembly GO:0007172 47 17 0,000 5,725E-03 0,0100623 ! filopodium assembly GO:0046847 42 17 0,000 5,725E-03 0,01005507 ! endothelial cell migration GO:0043542 31 17 0,000 5,725E-03 0,01004785 ! gene silencing by RNA GO:0031047 38 17 0,000 5,725E-03 0,01004063 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 5,725E-03 0,01003343 ! glial cell development GO:0021782 28 17 0,000 5,725E-03 0,01002624 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 5,725E-03 0,01001906 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 5,725E-03 0,01001188 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 5,725E-03 0,01000472 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 5,725E-03 9,998E-03 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 5,725E-03 9,99E-03 ! myoblast differentiation GO:0045445 50 17 0,000 5,725E-03 9,983E-03 ! activation of MAPKK activity GO:0000186 43 17 0,000 5,725E-03 9,976E-03 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 5,725E-03 9,969E-03 ! regulation of survival gene product expression GO:0045884 38 17 0,000 5,725E-03 9,962E-03 ! cardiac muscle tissue development GO:0048738 34 17 0,000 5,725E-03 9,955E-03 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 5,725E-03 9,948E-03 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 5,725E-03 9,941E-03 ! complement activation, alternative pathway GO:0006957 19 17 0,000 5,725E-03 9,934E-03 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 5,725E-03 9,927E-03 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 5,725E-03 9,92E-03 ! membrane budding GO:0006900 42 17 0,000 5,725E-03 9,913E-03 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 5,725E-03 9,906E-03 ! regulation of protein binding GO:0043393 33 17 0,000 5,725E-03 9,899E-03 ! nucleobase metabolic process GO:0009112 43 17 0,000 5,725E-03 9,892E-03 ! DNA unwinding during replication GO:0006268 26 17 0,000 5,725E-03 9,885E-03 ! genitalia development GO:0048806 32 17 0,000 5,725E-03 9,878E-03 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 5,725E-03 9,871E-03 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 5,725E-03 9,864E-03 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 5,725E-03 9,857E-03 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 5,725E-03 9,85E-03 ! neutrophil chemotaxis GO:0030593 29 17 0,000 5,725E-03 9,843E-03 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 5,725E-03 9,836E-03 ! steroid catabolic process GO:0006706 34 17 0,000 5,725E-03 9,829E-03 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 5,725E-03 9,822E-03 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 5,725E-03 9,815E-03 ! gas transport GO:0015669 26 17 0,000 5,725E-03 9,808E-03 ! organic cation transport GO:0015695 32 17 0,000 5,725E-03 9,801E-03 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 5,725E-03 9,795E-03 ! RNA 3'-end processing GO:0031123 37 17 0,000 5,725E-03 9,788E-03 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 5,725E-03 9,781E-03 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 6,061E-03 0,01034735 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 6,061E-03 0,01034012 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 6,061E-03 0,01033291 ! limbic system development GO:0021761 40 18 0,000 6,061E-03 0,0103257 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 6,061E-03 0,0103185 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 6,061E-03 0,01031132 ! adult walking behavior GO:0007628 36 18 0,000 6,061E-03 0,01030414 ! patterning of blood vessels GO:0001569 43 18 0,000 6,061E-03 0,01029698 ! heart looping GO:0001947 34 18 0,000 6,061E-03 0,01028982 ! ciliary or flagellar motility GO:0001539 32 18 0,000 6,061E-03 0,01028268 ! regulation of viral genome replication GO:0045069 30 18 0,000 6,061E-03 0,01027554 ! centrosome cycle GO:0007098 26 18 0,000 6,061E-03 0,01026841 ! positive regulation of proteolysis GO:0045862 36 18 0,000 6,061E-03 0,0102613 ! regulation of defense response to virus GO:0050688 35 18 0,000 6,061E-03 0,01025419 ! epidermis morphogenesis GO:0048730 43 18 0,000 6,061E-03 0,0102471 ! glycine metabolic process GO:0006544 30 18 0,000 6,061E-03 0,01024001 ! glutamine metabolic process GO:0006541 29 18 0,000 6,061E-03 0,01023293 ! response to retinoic acid GO:0032526 31 18 0,000 6,061E-03 0,01022587 ! cell-substrate junction assembly GO:0007044 56 18 0,000 6,061E-03 0,01021881 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 0,000 6,061E-03 0,01021176 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 6,061E-03 0,01020472 ! DNA integration GO:0015074 32 18 0,000 6,061E-03 0,0101977 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 6,061E-03 0,01019068 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 6,061E-03 0,01018367 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 6,061E-03 0,01017667 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 6,061E-03 0,01016968 ! neural crest cell migration GO:0001755 41 18 0,000 6,061E-03 0,0101627 ! sphingolipid catabolic process GO:0030149 32 18 0,000 6,061E-03 0,01015573 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 6,061E-03 0,01014877 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 6,061E-03 0,01014182 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 6,061E-03 0,01013488 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 6,061E-03 0,01012794 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 6,061E-03 0,01012102 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 6,061E-03 0,01011411 ! detection of bacterium GO:0016045 22 18 0,000 6,061E-03 0,0101072 ! nerve development GO:0021675 34 18 0,000 6,061E-03 0,01010031 ! defense response to virus GO:0051607 43 18 0,000 6,061E-03 0,01009342 ! microspike assembly GO:0030035 46 18 0,000 6,061E-03 0,01008655 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 6,061E-03 0,01007968 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 6,061E-03 0,01007283 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 6,397E-03 0,01062356 ! positive regulation of translation GO:0045727 31 19 0,000 6,397E-03 0,01061634 ! negative regulation of defense response GO:0031348 27 19 0,000 6,397E-03 0,01060913 ! neuron maturation GO:0042551 46 19 0,000 6,397E-03 0,01060193 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 6,397E-03 0,01059475 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 6,397E-03 0,01058757 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 6,397E-03 0,0105804 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 6,397E-03 0,01057324 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 6,397E-03 0,01056609 ! inositol metabolic process GO:0006020 33 19 0,000 6,397E-03 0,01055895 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 6,397E-03 0,01055182 ! memory GO:0007613 34 19 0,000 6,397E-03 0,0105447 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 6,397E-03 0,01053759 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 6,397E-03 0,01053049 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 6,397E-03 0,0105234 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 6,397E-03 0,01051632 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 6,397E-03 0,01050925 ! cerebral cortex development GO:0021987 40 19 0,000 6,397E-03 0,01050218 ! pigmentation during development GO:0048066 42 19 0,000 6,397E-03 0,01049513 ! response to vitamin A GO:0033189 32 19 0,000 6,397E-03 0,01048809 ! heme metabolic process GO:0042168 40 19 0,000 6,397E-03 0,01048105 ! neuromuscular junction development GO:0007528 43 19 0,000 6,397E-03 0,01047403 ! response to lipopolysaccharide GO:0032496 34 19 0,000 6,397E-03 0,01046701 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 6,397E-03 0,01046001 ! response to fungus GO:0009620 26 19 0,000 6,397E-03 0,01045301 ! peptide cross-linking GO:0018149 39 19 0,000 6,397E-03 0,01044602 ! protein export from nucleus GO:0006611 40 19 0,000 6,397E-03 0,01043905 ! heart process GO:0003015 32 19 0,000 6,397E-03 0,01043208 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 6,397E-03 0,01042512 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 6,397E-03 0,01041817 ! visual learning GO:0008542 38 19 0,000 6,397E-03 0,01041123 ! cellular pigmentation GO:0033059 37 19 0,000 6,397E-03 0,0104043 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 6,397E-03 0,01039737 ! peptide biosynthetic process GO:0043043 26 19 0,000 6,397E-03 0,01039046 ! vitamin transport GO:0051180 31 19 0,000 6,397E-03 0,01038356 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 6,397E-03 0,01037666 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 6,397E-03 0,01036978 ! proximal/distal pattern formation GO:0009954 33 19 0,000 6,397E-03 0,0103629 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 6,397E-03 0,01035603 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 6,397E-03 0,01034917 ! cilium assembly GO:0042384 38 19 0,000 6,397E-03 0,01034232 ! peptide hormone secretion GO:0030072 32 19 0,000 6,397E-03 0,01033548 ! protein secretion GO:0009306 45 20 0,000 6,732E-03 0,01087058 ! protein import into nucleus, docking GO:0000059 42 20 0,000 6,732E-03 0,0108634 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 6,732E-03 0,01085623 ! positive regulation of ossification GO:0045778 50 20 0,000 6,732E-03 0,01084907 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 6,732E-03 0,01084192 ! skin development GO:0043588 42 20 0,000 6,732E-03 0,01083478 ! phosphoinositide phosphorylation GO:0046854 40 20 0,000 6,732E-03 0,01082765 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 6,732E-03 0,01082052 ! protein amino acid deacetylation GO:0006476 34 20 0,000 6,732E-03 0,01081341 ! protein amino acid acetylation GO:0006473 41 20 0,000 6,732E-03 0,0108063 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 0,000 6,732E-03 0,01079921 ! aminoglycan catabolic process GO:0006026 25 20 0,000 6,732E-03 0,01079212 ! response to vitamin GO:0033273 36 20 0,000 6,732E-03 0,01078505 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 6,732E-03 0,01077798 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 6,732E-03 0,01077092 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 6,732E-03 0,01076387 ! bile acid metabolic process GO:0008206 34 20 0,000 6,732E-03 0,01075683 ! response to alkaloid GO:0043279 38 20 0,000 6,732E-03 0,0107498 ! retinoid metabolic process GO:0001523 34 20 0,000 6,732E-03 0,01074278 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 6,732E-03 0,01073577 ! apoptotic mitochondrial changes GO:0008637 42 20 0,000 6,732E-03 0,01072876 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 6,732E-03 0,01072177 ! DNA duplex unwinding GO:0032508 30 20 0,000 6,732E-03 0,01071478 GO:0032392|DNA geometric change, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 6,732E-03 0,01070781 ! actin filament bundle formation GO:0051017 47 20 0,000 6,732E-03 0,01070084 ! body fluid secretion GO:0007589 33 20 0,000 6,732E-03 0,01069388 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 6,732E-03 0,01068694 ! peptide secretion GO:0002790 38 20 0,000 6,732E-03 0,01068 ! behavioral interaction between organisms GO:0051705 47 20 0,000 6,732E-03 0,01067307 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 6,732E-03 0,01066614 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 6,732E-03 0,01065923 ! protein localization in mitochondrion GO:0070585 39 20 0,000 6,732E-03 0,01065233 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 6,732E-03 0,01064543 ! cell-cell junction organization GO:0045216 43 20 0,000 6,732E-03 0,01063855 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 6,732E-03 0,01063167 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 6,732E-03 0,0106248 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 6,732E-03 0,01061794 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 6,732E-03 0,01061109 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 6,732E-03 0,01060425 ! regulation of glucose import GO:0046324 30 20 0,000 6,732E-03 0,01059742 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 6,732E-03 0,0105906 ! negative regulation of T cell activation GO:0050868 41 20 0,000 6,732E-03 0,01058378 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 6,732E-03 0,01057697 ! negative regulation of translation GO:0017148 32 20 0,000 6,732E-03 0,01057018 ! negative regulation of coagulation GO:0050819 30 20 0,000 6,732E-03 0,01056339 ! regulation of cell killing GO:0031341 46 21 0,000 7,068E-03 0,01108272 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 7,068E-03 0,01107561 ! hormone secretion GO:0046879 39 21 0,000 7,068E-03 0,01106851 ! lipid phosphorylation GO:0046834 43 21 0,000 7,068E-03 0,01106142 ! cAMP metabolic process GO:0046058 41 21 0,000 7,068E-03 0,01105434 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 7,068E-03 0,01104727 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 7,068E-03 0,01104021 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 7,068E-03 0,01103315 ! ovarian follicle development GO:0001541 39 21 0,000 7,068E-03 0,01102611 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 0,000 7,068E-03 0,01101907 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 7,068E-03 0,01101204 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 7,068E-03 0,01100502 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 7,068E-03 0,01099801 ! plasma membrane fusion GO:0045026 33 21 0,000 7,068E-03 0,01099101 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 7,068E-03 0,01098402 ! prostaglandin metabolic process GO:0006693 43 21 0,000 7,068E-03 0,01097704 GO:0006692|prostanoid metabolic process, ! sensory perception of pain GO:0019233 33 21 0,000 7,068E-03 0,01097007 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 7,068E-03 0,0109631 ! diencephalon development GO:0021536 36 21 0,000 7,068E-03 0,01095614 ! collagen fibril organization GO:0030199 62 21 0,000 7,068E-03 0,0109492 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 7,068E-03 0,01094226 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 7,068E-03 0,01093533 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 7,068E-03 0,01092841 ! vitamin A metabolic process GO:0006776 35 21 0,000 7,068E-03 0,01092149 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 7,068E-03 0,01091459 ! collagen catabolic process GO:0030574 29 21 0,000 7,068E-03 0,0109077 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 7,068E-03 0,01090081 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 7,068E-03 0,01089393 ! sperm-egg recognition GO:0035036 23 21 0,000 7,068E-03 0,01088706 ! actin filament-based movement GO:0030048 47 21 0,000 7,068E-03 0,0108802 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 7,068E-03 0,01087335 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 7,403E-03 0,0113822 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 7,403E-03 0,01137504 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 7,403E-03 0,01136789 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 7,403E-03 0,01136075 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 7,403E-03 0,01135362 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 7,403E-03 0,0113465 ! microtubule-based transport GO:0010970 59 22 0,000 7,403E-03 0,01133938 ! hindlimb morphogenesis GO:0035137 47 22 0,000 7,403E-03 0,01133228 ! glutamate signaling pathway GO:0007215 48 22 0,000 7,403E-03 0,01132518 ! inactivation of MAPK activity GO:0000188 45 22 0,000 7,403E-03 0,0113181 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 7,403E-03 0,01131102 ! cellular response to starvation GO:0009267 37 22 0,000 7,403E-03 0,01130395 ! vacuolar transport GO:0007034 41 22 0,000 7,403E-03 0,01129689 ! central nervous system neuron development GO:0021954 47 22 0,000 7,403E-03 0,01128984 ! fucose metabolic process GO:0006004 44 22 0,000 7,403E-03 0,01128279 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 7,403E-03 0,01127576 ! D-ribose metabolic process GO:0006014 36 22 0,000 7,403E-03 0,01126873 ! apoptotic nuclear changes GO:0030262 34 22 0,000 7,403E-03 0,01126172 ! ureteric bud development GO:0001657 50 22 0,000 7,403E-03 0,01125471 ! cell aging GO:0007569 48 22 0,000 7,403E-03 0,01124771 ! stem cell differentiation GO:0048863 57 22 0,000 7,403E-03 0,01124072 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 7,403E-03 0,01123374 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 7,403E-03 0,01122676 ! cytolysis GO:0019835 27 22 0,000 7,403E-03 0,0112198 ! renal system process GO:0003014 42 22 0,000 7,403E-03 0,01121284 ! vasodilation GO:0042311 40 22 0,000 7,403E-03 0,0112059 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 7,403E-03 0,01119896 ! positive regulation of locomotion GO:0040017 44 22 0,000 7,403E-03 0,01119203 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! detection of chemical stimulus GO:0009593 42 22 0,000 7,403E-03 0,01118511 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 7,403E-03 0,01117819 ! positive regulation of intracellular transport GO:0032388 42 22 0,000 7,403E-03 0,01117129 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 7,403E-03 0,01116439 ! peptidyl-serine modification GO:0018209 50 22 0,000 7,403E-03 0,01115751 ! regulation of cytokine secretion GO:0050707 41 22 0,000 7,403E-03 0,01115063 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 7,403E-03 0,01114376 ! sarcomere organization GO:0045214 32 22 0,000 7,403E-03 0,0111369 ! positive regulation of B cell activation GO:0050871 42 22 0,000 7,403E-03 0,01113004 ! response to cytokine stimulus GO:0034097 69 22 0,000 7,403E-03 0,0111232 ! activation of JUN kinase activity GO:0007257 47 22 0,000 7,403E-03 0,01111636 ! terpenoid metabolic process GO:0006721 40 22 0,000 7,403E-03 0,01110953 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 7,403E-03 0,01110271 ! gut development GO:0048565 44 22 0,000 7,403E-03 0,0110959 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 7,403E-03 0,0110891 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 7,403E-03 0,0110823 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 7,403E-03 0,01107552 ! protein stabilization GO:0050821 41 22 0,000 7,403E-03 0,01106874 ! positive regulation of DNA replication GO:0045740 44 23 0,000 7,739E-03 0,011563 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 7,739E-03 0,01155593 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 7,739E-03 0,01154887 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 7,739E-03 0,01154182 ! gluconeogenesis GO:0006094 38 23 0,000 7,739E-03 0,01153478 ! glycerol metabolic process GO:0006071 40 23 0,000 7,739E-03 0,01152774 ! viral genome replication GO:0019079 44 23 0,000 7,739E-03 0,01152072 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 7,739E-03 0,0115137 ! glucosamine metabolic process GO:0006041 31 23 0,000 7,739E-03 0,01150669 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 7,739E-03 0,0114997 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 7,739E-03 0,01149271 ! regeneration GO:0031099 42 23 0,000 7,739E-03 0,01148572 ! axis specification GO:0009798 43 23 0,000 7,739E-03 0,01147875 ! visual behavior GO:0007632 46 23 0,000 7,739E-03 0,01147178 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 7,739E-03 0,01146483 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 7,739E-03 0,01145788 ! response to ethanol GO:0045471 47 23 0,000 7,739E-03 0,01145094 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 7,739E-03 0,01144401 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 7,739E-03 0,01143708 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 7,739E-03 0,01143017 ! peroxisome organization GO:0007031 43 23 0,000 7,739E-03 0,01142326 ! lysosome organization GO:0007040 47 23 0,000 7,739E-03 0,01141636 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 7,739E-03 0,01140947 ! vesicle targeting GO:0006903 49 23 0,000 7,739E-03 0,01140259 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 7,739E-03 0,01139572 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 7,739E-03 0,01138886 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 7,739E-03 0,011382 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 7,739E-03 0,01137515 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 7,739E-03 0,01136831 ! DNA modification GO:0006304 36 23 0,000 7,739E-03 0,01136148 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 7,739E-03 0,01135465 ! regulation of bone mineralization GO:0030500 54 23 0,000 7,739E-03 0,01134784 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 7,739E-03 0,01134103 ! hormone transport GO:0009914 41 23 0,000 7,739E-03 0,01133423 ! cell-cell recognition GO:0009988 28 23 0,000 7,739E-03 0,01132744 ! negative regulation of cytokine production GO:0001818 41 23 0,000 7,739E-03 0,01132066 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 7,739E-03 0,01131388 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 7,739E-03 0,01130712 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 8,074E-03 0,01178986 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 8,074E-03 0,01178281 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 8,074E-03 0,01177578 ! regulation of cellular catabolic process GO:0031329 55 24 0,000 8,074E-03 0,01176875 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 8,074E-03 0,01176173 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 8,074E-03 0,01175472 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 8,074E-03 0,01174772 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 8,074E-03 0,01174073 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 8,074E-03 0,01173375 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 8,074E-03 0,01172677 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 8,074E-03 0,0117198 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 0,000 8,074E-03 0,01171284 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 8,074E-03 0,01170589 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 8,074E-03 0,01169895 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 8,074E-03 0,01169201 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 8,074E-03 0,01168509 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 8,074E-03 0,01167817 ! barbed-end actin filament capping GO:0051016 58 24 0,000 8,074E-03 0,01167126 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 8,074E-03 0,01166436 ! regulation of viral reproduction GO:0050792 41 24 0,000 8,074E-03 0,01165746 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 8,074E-03 0,01165058 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 52 24 0,000 8,074E-03 0,0116437 ! leukotriene metabolic process GO:0006691 47 24 0,000 8,074E-03 0,01163683 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 8,074E-03 0,01162997 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 8,074E-03 0,01162312 ! membrane depolarization GO:0051899 45 24 0,000 8,074E-03 0,01161627 ! pallium development GO:0021543 56 24 0,000 8,074E-03 0,01160943 ! oogenesis GO:0048477 44 24 0,000 8,074E-03 0,0116026 ! synaptic vesicle transport GO:0048489 52 24 0,000 8,074E-03 0,01159578 ! detection of biotic stimulus GO:0009595 34 24 0,000 8,074E-03 0,01158897 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 8,074E-03 0,01158217 ! platelet activation GO:0030168 41 24 0,000 8,074E-03 0,01157537 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 8,074E-03 0,01156858 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 8,074E-03 0,0115618 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 8,074E-03 0,01155502 ! porphyrin metabolic process GO:0006778 50 24 0,000 8,074E-03 0,01154826 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 8,074E-03 0,0115415 ! negative regulation of catabolic process GO:0009895 52 24 0,000 8,074E-03 0,01153475 ! regulation of amine transport GO:0051952 41 24 0,000 8,074E-03 0,01152801 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 8,074E-03 0,01152128 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 8,409E-03 0,01199247 ! positive regulation of fibroblast proliferation GO:0048146 48 25 0,000 8,409E-03 0,01198547 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 8,409E-03 0,01197849 ! regulation of transmembrane transport GO:0034762 39 25 0,000 8,409E-03 0,0119715 ! leukocyte adhesion GO:0007159 55 25 0,000 8,409E-03 0,01196453 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 8,409E-03 0,01195757 ! phototransduction GO:0007602 37 25 0,000 8,409E-03 0,01195061 ! keratinization GO:0031424 37 25 0,000 8,409E-03 0,01194366 ! vasculogenesis GO:0001570 49 25 0,000 8,409E-03 0,01193672 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 8,409E-03 0,01192979 ! vacuole organization GO:0007033 49 25 0,000 8,409E-03 0,01192287 ! polysaccharide catabolic process GO:0000272 30 25 0,000 8,409E-03 0,01191595 ! negative regulation of DNA replication GO:0008156 45 25 0,000 8,409E-03 0,01190904 ! receptor metabolic process GO:0043112 53 25 0,000 8,409E-03 0,01190214 ! chromosome condensation GO:0030261 48 25 0,000 8,409E-03 0,01189525 ! regulation of insulin secretion GO:0050796 42 25 0,000 8,409E-03 0,01188837 ! regulation of behavior GO:0050795 48 25 0,000 8,409E-03 0,01188149 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 8,409E-03 0,01187463 ! interaction with host GO:0051701 66 25 0,000 8,409E-03 0,01186777 ! lymphocyte proliferation GO:0046651 55 25 0,000 8,409E-03 0,01186091 ! regulation of biomineral formation GO:0070167 56 25 0,000 8,409E-03 0,01185407 ! immunoglobulin production GO:0002377 62 25 0,000 8,409E-03 0,01184723 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 8,409E-03 0,0118404 ! cellular alkene metabolic process GO:0043449 48 25 0,000 8,409E-03 0,01183358 ! liver development GO:0001889 55 25 0,000 8,409E-03 0,01182677 ! protein tetramerization GO:0051262 57 25 0,000 8,409E-03 0,01181997 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 8,744E-03 0,0122838 ! myelination GO:0042552 50 26 0,000 8,744E-03 0,01227674 ! initiation of viral infection GO:0019059 60 26 0,000 8,744E-03 0,01226969 ! pyruvate metabolic process GO:0006090 43 26 0,000 8,744E-03 0,01226264 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 8,744E-03 0,01225561 ! molting cycle process GO:0022404 52 26 0,000 8,744E-03 0,01224858 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 8,744E-03 0,01224156 ! protein amino acid alkylation GO:0008213 59 26 0,000 8,744E-03 0,01223455 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 8,744E-03 0,01222755 ! microtubule organizing center organization GO:0031023 42 26 0,000 8,744E-03 0,01222055 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 8,744E-03 0,01221356 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 8,744E-03 0,01220658 ! multicellular organismal response to stress GO:0033555 61 26 0,000 8,744E-03 0,01219961 ! digestive system process GO:0022600 49 26 0,000 8,744E-03 0,01219265 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 8,744E-03 0,01218569 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 8,744E-03 0,01217875 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 0,000 8,744E-03 0,01217181 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 8,744E-03 0,01216488 ! osteoblast differentiation GO:0001649 63 26 0,000 8,744E-03 0,01215795 ! neural crest cell development GO:0014032 59 26 0,000 8,744E-03 0,01215104 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 8,744E-03 0,01214413 ! negative regulation of cell development GO:0010721 83 26 0,000 8,744E-03 0,01213723 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 8,744E-03 0,01213034 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 8,744E-03 0,01212345 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 8,744E-03 0,01211658 ! response to estradiol stimulus GO:0032355 43 26 0,000 8,744E-03 0,01210971 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 8,744E-03 0,01210285 ! regulation of blood coagulation GO:0030193 46 26 0,000 8,744E-03 0,01209599 ! positive regulation of nuclear division GO:0051785 41 26 0,000 8,744E-03 0,01208915 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 8,744E-03 0,01208231 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 8,744E-03 0,01207548 ! blastocyst development GO:0001824 50 26 0,000 8,744E-03 0,01206866 ! telomere organization GO:0032200 46 26 0,000 8,744E-03 0,01206184 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 8,744E-03 0,01205504 ! neural tube closure GO:0001843 58 26 0,000 8,744E-03 0,01204824 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 8,744E-03 0,01204144 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 8,744E-03 0,01203466 ! regulation of multi-organism process GO:0043900 45 26 0,000 8,744E-03 0,01202788 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 9,079E-03 0,01248154 ! embryonic pattern specification GO:0009880 49 27 0,000 9,079E-03 0,01247452 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 9,079E-03 0,0124675 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 9,079E-03 0,0124605 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 9,079E-03 0,0124535 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 9,079E-03 0,01244651 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 9,079E-03 0,01243953 ! iron ion transport GO:0006826 65 27 0,000 9,079E-03 0,01243256 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 9,079E-03 0,0124256 ! superoxide metabolic process GO:0006801 41 27 0,000 9,079E-03 0,01241864 ! tube lumen formation GO:0035148 59 27 0,000 9,079E-03 0,01241169 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 9,079E-03 0,01240475 ! insulin receptor signaling pathway GO:0008286 66 27 0,000 9,079E-03 0,01239781 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 9,079E-03 0,01239089 ! mitochondrial membrane organization GO:0007006 60 27 0,000 9,079E-03 0,01238397 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 9,079E-03 0,01237706 ! response to starvation GO:0042594 47 27 0,000 9,079E-03 0,01237016 ! response to toxin GO:0009636 49 27 0,000 9,079E-03 0,01236326 ! cellular response to oxidative stress GO:0034599 43 27 0,000 9,079E-03 0,01235637 ! regulation of chromosome organization GO:0033044 49 27 0,000 9,079E-03 0,01234949 ! cellular response to nutrient levels GO:0031669 45 27 0,000 9,079E-03 0,01234262 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 9,079E-03 0,01233576 ! leukocyte proliferation GO:0070661 59 27 0,000 9,079E-03 0,0123289 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 9,079E-03 0,01232205 ! regulation of fibroblast proliferation GO:0048145 56 28 0,000 9,414E-03 0,01276935 ! neuron fate commitment GO:0048663 52 28 0,000 9,414E-03 0,01276227 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 0,000 9,414E-03 0,01275519 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 9,414E-03 0,01274812 ! protein amino acid acylation GO:0043543 59 28 0,000 9,414E-03 0,01274105 ! vesicle docking GO:0048278 55 28 0,000 9,414E-03 0,012734 ! circadian rhythm GO:0007623 56 28 0,000 9,414E-03 0,01272695 ! dendrite development GO:0016358 67 28 0,000 9,414E-03 0,01271991 ! negative regulation of protein modification process GO:0031400 66 28 0,000 9,414E-03 0,01271288 ! positive regulation of innate immune response GO:0045089 49 28 0,000 9,414E-03 0,01270586 ! sperm motility GO:0030317 37 28 0,000 9,414E-03 0,01269884 ! vitamin biosynthetic process GO:0009110 48 28 0,000 9,414E-03 0,01269183 ! base-excision repair GO:0006284 41 28 0,000 9,414E-03 0,01268483 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 9,414E-03 0,01267784 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 9,414E-03 0,01267086 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 9,414E-03 0,01266388 ! glycolipid metabolic process GO:0006664 50 28 0,000 9,414E-03 0,01265691 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 9,414E-03 0,01264995 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 9,414E-03 0,01264299 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 9,414E-03 0,01263605 ! glutathione metabolic process GO:0006749 42 28 0,000 9,414E-03 0,01262911 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 9,414E-03 0,01262218 ! lipid oxidation GO:0034440 48 28 0,000 9,414E-03 0,01261525 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 9,414E-03 0,01260834 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 9,414E-03 0,01260143 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 9,748E-03 0,01304231 ! translational initiation GO:0006413 66 29 0,000 9,748E-03 0,01303517 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 9,748E-03 0,01302804 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 9,748E-03 0,01302092 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 9,748E-03 0,01301381 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 9,748E-03 0,0130067 ! respiratory gaseous exchange GO:0007585 61 29 0,000 9,748E-03 0,0129996 ! primary neural tube formation GO:0014020 61 29 0,000 9,748E-03 0,01299251 ! regulation of peptide secretion GO:0002791 52 29 0,000 9,748E-03 0,01298542 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 9,748E-03 0,01297835 ! response to organic cyclic substance GO:0014070 58 29 0,000 9,748E-03 0,01297128 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 9,748E-03 0,01296422 ! somitogenesis GO:0001756 52 29 0,000 9,748E-03 0,01295716 ! synaptogenesis GO:0007416 46 29 0,000 9,748E-03 0,01295012 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 9,748E-03 0,01294308 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 9,748E-03 0,01293605 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 9,748E-03 0,01292902 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 9,748E-03 0,01292201 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,01008296 0,01335828 ! phenol metabolic process GO:0018958 56 30 0,000 0,01008296 0,01335104 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,01008296 0,01334381 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,01008296 0,01333658 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,01008296 0,01332937 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,01008296 0,01332216 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,01008296 0,01331496 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,01008296 0,01330776 ! acute-phase response GO:0006953 50 30 0,000 0,01008296 0,01330058 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,01008296 0,0132934 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,01008296 0,01328623 ! myofibril assembly GO:0030239 50 30 0,000 0,01008296 0,01327907 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,01008296 0,01327191 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,01008296 0,01326477 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,01008296 0,01325763 ! cell fate determination GO:0001709 64 30 0,000 0,01008296 0,0132505 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,01008296 0,01324337 ! phospholipid transport GO:0015914 65 30 0,000 0,01008296 0,01323626 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,01008296 0,01322915 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,01008296 0,01322205 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,01008296 0,01321495 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,01008296 0,01320787 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,01008296 0,01320079 GO:0048871|multicellular organismal homeostasis, ! regulation of B cell activation GO:0050864 55 30 0,000 0,01008296 0,01319372 ! regulation of coagulation GO:0050818 52 30 0,000 0,01008296 0,01318665 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,01041745 0,01361681 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,01041745 0,01360953 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,01041745 0,01360226 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,01041745 0,01359499 ! cell junction assembly GO:0034329 85 31 0,000 0,01041745 0,01358773 ! regulation of innate immune response GO:0045088 57 31 0,000 0,01041745 0,01358048 ! ovulation cycle process GO:0022602 55 31 0,000 0,01041745 0,01357324 ! peptide transport GO:0015833 60 31 0,000 0,01041745 0,013566 ! male gonad development GO:0008584 56 31 0,000 0,01041745 0,01355878 ! iron ion homeostasis GO:0055072 60 31 0,000 0,01041745 0,01355156 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,01041745 0,01354435 ! detection of light stimulus GO:0009583 44 31 0,000 0,01041745 0,01353714 ! cellular response to extracellular stimulus GO:0031668 52 31 0,000 0,01041745 0,01352994 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,01041745 0,01352276 ! natural killer cell activation GO:0030101 50 31 0,000 0,01041745 0,01351557 ! ensheathment of neurons GO:0007272 64 31 0,000 0,01041745 0,0135084 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,01041745 0,01350123 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,01041745 0,01349407 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,01041745 0,01348692 ! eye morphogenesis GO:0048592 65 31 0,000 0,01041745 0,01347978 ! response to heat GO:0009408 54 31 0,000 0,01041745 0,01347264 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,01041745 0,01346552 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,01075183 0,01389039 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,01075183 0,01388305 ! collagen metabolic process GO:0032963 49 32 0,000 0,01075183 0,01387571 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,01075183 0,01386839 ! spindle organization GO:0007051 50 32 0,000 0,01075183 0,01386107 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,01075183 0,01385376 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,01075183 0,01384646 ! metanephros development GO:0001656 81 32 0,000 0,01075183 0,01383916 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,01075183 0,01383187 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,01075183 0,01382459 ! muscle cell development GO:0055001 52 32 0,000 0,01075183 0,01381732 ! mesoderm formation GO:0001707 73 32 0,000 0,01075183 0,01381006 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,01075183 0,0138028 ! ovulation cycle GO:0042698 57 32 0,000 0,01075183 0,01379555 ! peripheral nervous system development GO:0007422 68 32 0,000 0,01075183 0,01378831 ! BMP signaling pathway GO:0030509 71 32 0,000 0,01075183 0,01378107 ! hindbrain development GO:0030902 65 32 0,000 0,01075183 0,01377385 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,01075183 0,01376663 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,01075183 0,01375942 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,01075183 0,01375221 ! gene silencing GO:0016458 71 32 0,000 0,01075183 0,01374502 ! regulation of pH GO:0006885 56 33 0,000 0,01108611 0,01416494 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,01108611 0,01415754 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,01108611 0,01415014 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,01108611 0,01414275 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,01108611 0,01413537 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,01108611 0,014128 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,01108611 0,01412063 ! response to ionizing radiation GO:0010212 74 33 0,000 0,01108611 0,01411327 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,01108611 0,01410592 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,01108611 0,01409858 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,01108611 0,01409125 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,01108611 0,01408392 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,01108611 0,0140766 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,01108611 0,01406929 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,01108611 0,01406198 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,01142029 0,01447834 ! glial cell differentiation GO:0010001 67 34 0,000 0,01142029 0,01447083 ! post-embryonic development GO:0009791 76 34 0,000 0,01142029 0,01446333 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,01142029 0,01445584 ! cholesterol transport GO:0030301 62 34 0,000 0,01142029 0,01444835 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,01142029 0,01444087 ! spliceosome assembly GO:0000245 75 34 0,000 0,01142029 0,0144334 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,01142029 0,01442594 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,01142029 0,01441849 ! formation of primary germ layer GO:0001704 76 34 0,000 0,01142029 0,01441104 ! cell fate specification GO:0001708 56 34 0,000 0,01142029 0,0144036 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,01142029 0,01439617 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,01142029 0,01438874 ! adult locomotory behavior GO:0008344 62 34 0,000 0,01142029 0,01438132 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,01142029 0,01437391 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,01175436 0,01478677 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,01175436 0,01477916 ! negative regulation of secretion GO:0051048 68 35 0,000 0,01175436 0,01477156 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,01175436 0,01476396 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,01175436 0,01475638 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,01175436 0,0147488 ! membrane docking GO:0022406 69 35 0,000 0,01175436 0,01474123 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,01175436 0,01473366 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,01175436 0,01472611 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,01175436 0,01471856 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,01175436 0,01471102 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,01175436 0,01470349 ! ceramide metabolic process GO:0006672 72 35 0,000 0,01175436 0,01469596 ! telencephalon development GO:0021537 81 35 0,000 0,01175436 0,01468845 ! sterol transport GO:0015918 63 35 0,000 0,01175436 0,01468094 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,01175436 0,01467343 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,01175436 0,01466594 ! placenta development GO:0001890 53 35 0,000 0,01175436 0,01465845 ! vesicle localization GO:0051648 70 35 0,000 0,01175436 0,01465097 ! regulation of muscle development GO:0048634 82 36 0,000 0,01208833 0,01505956 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,01208833 0,01505189 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,01208833 0,01504422 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,01208833 0,01503656 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,01208833 0,01502891 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,01208833 0,01502126 ! positive regulation of cell development GO:0010720 85 36 0,000 0,01208833 0,01501362 ! protein targeting to membrane GO:0006612 75 36 0,000 0,01208833 0,015006 ! regulation of proteolysis GO:0030162 77 36 0,000 0,01208833 0,01499837 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,01208833 0,01499076 ! aerobic respiration GO:0009060 56 36 0,000 0,01208833 0,01498316 ! cytokine production GO:0001816 68 36 0,000 0,01208833 0,01497556 ! embryonic organ development GO:0048568 67 36 0,000 0,01208833 0,01496797 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,01208833 0,01496038 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,01208833 0,01495281 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,0124222 0,01535801 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,0124222 0,01535025 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,0124222 0,01534249 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,0124222 0,01533473 ! sister chromatid segregation GO:0000819 65 37 0,000 0,0124222 0,01532699 ! odontogenesis GO:0042476 74 37 0,000 0,0124222 0,01531925 ! actomyosin structure organization GO:0031032 68 37 0,000 0,0124222 0,01531152 ! cell junction organization GO:0034330 96 37 0,000 0,0124222 0,0153038 ! tissue remodeling GO:0048771 78 37 0,000 0,0124222 0,01529609 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,0124222 0,01528838 ! female gonad development GO:0008585 71 37 0,000 0,0124222 0,01528068 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,0124222 0,01527299 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,0124222 0,01526531 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,0124222 0,01525764 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,0124222 0,01524997 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,01275596 0,01565184 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,01275596 0,01564399 ! meiosis I GO:0007127 74 38 0,000 0,01275596 0,01563614 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,01275596 0,01562829 ! organic anion transport GO:0015711 82 38 0,000 0,01275596 0,01562046 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,01275596 0,01561264 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,01275596 0,01560482 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,01275596 0,01559701 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,01275596 0,0155892 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,01275596 0,01558141 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,01275596 0,01557362 ! regulation of protein stability GO:0031647 77 38 0,000 0,01275596 0,01556584 ! spermatid development GO:0007286 69 38 0,000 0,01275596 0,01555807 ! glycogen metabolic process GO:0005977 63 38 0,000 0,01275596 0,01555031 ! pigment metabolic process GO:0042440 87 38 0,000 0,01275596 0,01554255 ! cellular response to insulin stimulus GO:0032869 85 38 0,000 0,01275596 0,01553481 ! neural tube formation GO:0001841 79 38 0,000 0,01275596 0,01552707 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,01308962 0,01592527 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,01308962 0,01591735 ! negative regulation of binding GO:0051100 71 39 0,000 0,01308962 0,01590943 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,01308962 0,01590152 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,01308962 0,01589361 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,01308962 0,01588572 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,01308962 0,01587783 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,01308962 0,01586995 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,01308962 0,01586208 ! positive regulation of leukocyte proliferation GO:0070665 70 39 0,000 0,01308962 0,01585421 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,01308962 0,01584636 ! glucan metabolic process GO:0044042 64 39 0,000 0,01308962 0,01583851 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,01342318 0,01623407 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 0,000 0,01342318 0,01622604 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,01342318 0,01621802 ! learning GO:0007612 82 40 0,000 0,01342318 0,01621 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,01342318 0,01620199 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,01342318 0,01619399 ! lipid homeostasis GO:0055088 75 40 0,000 0,01342318 0,016186 ! mismatch repair GO:0006298 58 40 0,000 0,01342318 0,01617801 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,01342318 0,01617003 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,01342318 0,01616207 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,01342318 0,0161541 ! RNA export from nucleus GO:0006405 61 41 0,000 0,01375663 0,01654725 ! mRNA catabolic process GO:0006402 79 41 0,000 0,01375663 0,0165391 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,01375663 0,01653097 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,01375663 0,01652284 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,01375663 0,01651472 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,01375663 0,01650661 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,01375663 0,01649851 ! gliogenesis GO:0042063 91 41 0,000 0,01375663 0,01649041 ! feeding behavior GO:0007631 69 41 0,000 0,01375663 0,01648232 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,01375663 0,01647424 ! mesenchymal cell development GO:0014031 94 41 0,000 0,01375663 0,01646617 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,01375663 0,01645811 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,01375663 0,01645005 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,01375663 0,016442 ! spermatid differentiation GO:0048515 73 41 0,000 0,01375663 0,01643396 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,01375663 0,01642593 ! RNA modification GO:0009451 64 41 0,000 0,01375663 0,01641791 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,01408998 0,01680753 ! ear morphogenesis GO:0042471 64 42 0,000 0,01408998 0,01679933 ! organic ether metabolic process GO:0018904 59 42 0,000 0,01408998 0,01679114 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,01408998 0,01678295 ! regulation of intracellular protein transport GO:0033157 86 42 0,000 0,01408998 0,01677477 ! T cell differentiation GO:0030217 93 42 0,000 0,01408998 0,0167666 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,01408998 0,01675844 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,01408998 0,01675028 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,01408998 0,01674214 ! regulation of protein secretion GO:0050708 77 42 0,000 0,01408998 0,016734 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,01408998 0,01672586 ! cytokinesis GO:0000910 84 42 0,000 0,01408998 0,01671774 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,01408998 0,01670963 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,01442323 0,01709653 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 0,000 0,01442323 0,01708824 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,01442323 0,01707996 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,01442323 0,01707168 ! regulation of tube size GO:0035150 76 43 0,000 0,01442323 0,01706341 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,01442323 0,01705516 ! glucose transport GO:0015758 66 43 0,000 0,01442323 0,0170469 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,01442323 0,01703866 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,01442323 0,01703043 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,01442323 0,0170222 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,01442323 0,01701398 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,01442323 0,01700577 ! segmentation GO:0035282 78 43 0,000 0,01442323 0,01699756 ! ion transmembrane transport GO:0034220 79 43 0,000 0,01442323 0,01698937 ! neuron migration GO:0001764 85 43 0,000 0,01442323 0,01698118 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,01442323 0,016973 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,01475637 0,01735668 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,01475637 0,01734833 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,01475637 0,01733998 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,01475637 0,01733164 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,01475637 0,01732332 ! hexose transport GO:0008645 68 44 0,000 0,01475637 0,017315 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,01475637 0,01730668 ! striated muscle contraction GO:0006941 85 44 0,000 0,01475637 0,01729838 ! phagocytosis GO:0006909 105 44 0,000 0,01475637 0,01729008 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,01475637 0,01728179 ! double-strand break repair GO:0006302 85 44 0,000 0,01475637 0,01727351 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,01508941 0,0176549 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,01508941 0,01764645 ! regulation of epithelial cell proliferation GO:0050678 122 45 0,000 0,01508941 0,01763801 ! induction of apoptosis by intracellular signals GO:0008629 95 45 0,000 0,01508941 0,01762957 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,01508941 0,01762115 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,01508941 0,01761273 ! biopolymer methylation GO:0043414 91 45 0,000 0,01508941 0,01760432 ! B cell differentiation GO:0030183 124 45 0,000 0,01508941 0,01759591 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,01508941 0,01758752 ! female gamete generation GO:0007292 71 45 0,000 0,01508941 0,01757913 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,01508941 0,01757075 ! polyol metabolic process GO:0019751 77 45 0,000 0,01508941 0,01756238 ! developmental growth GO:0048589 88 45 0,000 0,01508941 0,01755402 ! maintenance of location in cell GO:0051651 101 45 0,000 0,01508941 0,01754566 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,01542235 0,01792426 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,01542235 0,01791574 ! glycolysis GO:0006096 71 46 0,000 0,01542235 0,01790723 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 0,000 0,01542235 0,01789872 ! regulation of gene-specific transcription GO:0032583 102 46 0,000 0,01542235 0,01789022 ! leukocyte migration GO:0050900 75 46 0,000 0,01542235 0,01788173 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,01542235 0,01787325 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,01542235 0,01786477 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,01542235 0,0178563 ! pigmentation GO:0043473 103 46 0,000 0,01542235 0,01784785 ! cell growth GO:0016049 90 46 0,000 0,01542235 0,01783939 ! positive regulation of protein transport GO:0051222 80 46 0,000 0,01542235 0,01783095 ! neural tube development GO:0021915 91 47 0,000 0,01575518 0,01820715 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,01575518 0,01819854 ! response to insulin stimulus GO:0032868 98 47 0,000 0,01575518 0,01818994 ! positive regulation of defense response GO:0031349 88 48 0,000 0,01608791 0,01856532 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,01608791 0,01855655 ! mitochondrial transport GO:0006839 94 48 0,000 0,01608791 0,01854779 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,01608791 0,01853905 ! cellular component disassembly GO:0022411 89 48 0,000 0,01608791 0,0185303 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,01608791 0,01852157 ! endosome transport GO:0016197 127 48 0,000 0,01608791 0,01851285 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,01608791 0,01850413 ! male sex differentiation GO:0046661 93 48 0,000 0,01608791 0,01849542 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,01608791 0,01848672 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,01608791 0,01847803 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,01608791 0,01846935 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,01608791 0,01846067 ! methylation GO:0032259 97 48 0,000 0,01608791 0,01845201 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,01642054 0,01882468 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,01642054 0,01881585 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,01642054 0,01880703 ! JNK cascade GO:0007254 106 49 0,000 0,01642054 0,01879821 ! regulation of mast cell proliferation GO:0070666 89 49 0,000 0,01642054 0,01878941 ! protein homooligomerization GO:0051260 84 49 0,000 0,01642054 0,01878061 ! regulation of action potential GO:0001508 102 50 0,000 0,01675307 0,01915196 ! regulation of ion transport GO:0043269 86 50 0,000 0,01675307 0,019143 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,01675307 0,01913405 ! endocrine system development GO:0035270 109 50 0,000 0,01675307 0,01912511 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,01675307 0,01911618 ! activation of caspase activity GO:0006919 95 50 0,000 0,01675307 0,01910726 ! regulation of ossification GO:0030278 123 50 0,000 0,01675307 0,01909834 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,01675307 0,01908943 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,01675307 0,01908053 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,01675307 0,01907164 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,01675307 0,01906276 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,01675307 0,01905388 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,01708549 0,01942292 ! viral infectious cycle GO:0019058 104 51 0,000 0,01708549 0,01941388 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,01708549 0,01940486 ! peptide metabolic process GO:0006518 80 51 0,000 0,01708549 0,01939584 ! response to temperature stimulus GO:0009266 84 51 0,000 0,01708549 0,01938683 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,01708549 0,01937783 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,01708549 0,01936884 ! positive regulation of binding GO:0051099 88 52 0,000 0,01741781 0,01973641 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,01741781 0,01972726 ! Notch signaling pathway GO:0007219 111 52 0,000 0,01741781 0,01971812 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,01741781 0,01970899 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,01741781 0,01969986 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,01741781 0,01969075 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,01741781 0,01968164 ! excretion GO:0007588 87 52 0,000 0,01741781 0,01967254 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,01741781 0,01966345 ! histone modification GO:0016570 104 52 0,000 0,01741781 0,01965437 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,01741781 0,01964529 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,01741781 0,01963623 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,01741781 0,01962717 ! amino acid activation GO:0043038 98 52 0,000 0,01741781 0,01961812 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,01775002 0,01998309 ! positive regulation of growth GO:0045927 96 53 0,000 0,01775002 0,01997388 ! inner ear development GO:0048839 89 53 0,000 0,01775002 0,01996469 ! chromatin remodeling GO:0006338 122 53 0,000 0,01775002 0,0199555 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,01775002 0,01994632 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,01775002 0,01993715 ! vesicle organization GO:0016050 127 53 0,000 0,01775002 0,01992799 ! regulation of leukocyte proliferation GO:0070663 97 53 0,000 0,01775002 0,01991883 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,01775002 0,01990969 ! cartilage development GO:0051216 99 53 0,000 0,01775002 0,01990055 ! synapse organization GO:0050808 102 53 0,000 0,01775002 0,01989142 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,01808213 0,02025431 ! regulation of translational initiation GO:0006446 87 54 0,000 0,01808213 0,02024503 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,01808213 0,02023576 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,01808213 0,02022649 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 0,000 0,01808213 0,02021723 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,01808213 0,02020798 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,01808213 0,02019874 ! membrane fusion GO:0006944 122 54 0,000 0,01808213 0,02018951 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,01808213 0,02018029 ! covalent chromatin modification GO:0016569 115 54 0,000 0,01808213 0,02017107 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,01808213 0,02016187 ! regulation of cell shape GO:0008360 142 54 0,000 0,01808213 0,02015267 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,01808213 0,02014348 ! RNA catabolic process GO:0006401 103 55 0,000 0,01841414 0,02050399 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,01841414 0,02049465 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,01841414 0,02048532 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,01841414 0,02047599 ! cell recognition GO:0008037 98 55 0,000 0,01841414 0,02046668 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,01841414 0,02045737 ! cell maturation GO:0048469 107 55 0,000 0,01841414 0,02044807 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,01841414 0,02043878 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,01841414 0,0204295 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,01874605 0,02078829 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,01874605 0,02077886 ! glucose catabolic process GO:0006007 88 56 0,000 0,01874605 0,02076943 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,01874605 0,02076002 ! RNA elongation GO:0006354 90 56 0,000 0,01874605 0,02075061 ! chloride transport GO:0006821 102 57 0,000 0,01907785 0,02110833 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,01907785 0,02109878 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,01907785 0,02108923 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 131 57 0,000 0,01907785 0,02107969 ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,01907785 0,02107016 ! heart morphogenesis GO:0003007 105 57 0,000 0,01907785 0,02106064 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,01907785 0,02105113 ! regulation of intracellular transport GO:0032386 108 57 0,000 0,01907785 0,02104162 ! regulation of actin filament length GO:0030832 118 58 0,000 0,01940955 0,02139781 ! positive regulation of cell migration GO:0030335 137 58 0,000 0,01940955 0,02138816 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,01940955 0,02137851 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,01940955 0,02136888 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,01940955 0,02135925 ! aging GO:0007568 112 58 0,000 0,01940955 0,02134964 ! gastrulation GO:0007369 122 58 0,000 0,01940955 0,02134003 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,01940955 0,02133043 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,01940955 0,02132084 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,01940955 0,02131125 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,01940955 0,02130168 ! maintenance of location GO:0051235 124 58 0,000 0,01940955 0,02129212 ! nuclear export GO:0051168 110 59 0,000 0,01974115 0,02164616 ! establishment of organelle localization GO:0051656 122 59 0,000 0,01974115 0,02163644 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,02007265 0,0219899 ! lipid modification GO:0030258 112 60 0,000 0,02007265 0,02198004 ! DNA catabolic process GO:0006308 94 60 0,000 0,02007265 0,0219702 ! regulation of endocytosis GO:0030100 104 60 0,000 0,02007265 0,02196036 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,02007265 0,02195053 ! adult behavior GO:0030534 104 60 0,000 0,02007265 0,02194071 ! kidney development GO:0001822 133 60 0,000 0,02007265 0,02193089 ! positive regulation of secretion GO:0051047 110 61 0,000 0,02040404 0,022283 ! regulation of cellular component size GO:0032535 125 61 0,000 0,02040404 0,02227304 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,02040404 0,02226309 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,02040404 0,02225316 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,02040404 0,02224323 ! regulation of heart contraction GO:0008016 123 61 0,000 0,02040404 0,0222333 ! camera-type eye development GO:0043010 126 61 0,000 0,02040404 0,02222339 ! proton transport GO:0015992 117 61 0,000 0,02040404 0,02221349 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,02040404 0,02220359 ! viral reproductive process GO:0022415 132 62 0,000 0,02073533 0,02255406 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,02073533 0,02254402 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,02073533 0,02253399 ! tRNA processing GO:0008033 102 62 0,000 0,02073533 0,02252397 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,02073533 0,02251396 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,02106652 0,02286339 ! regulation of mitosis GO:0007088 112 63 0,000 0,02106652 0,02285324 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 0,000 0,02106652 0,0228431 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,02106652 0,02283296 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,02106652 0,02282284 ! hydrogen transport GO:0006818 121 64 0,000 0,0213976 0,02317125 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,0213976 0,02316098 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,0213976 0,02315073 ! protein amino acid autophosphorylation GO:0046777 157 64 0,000 0,0213976 0,02314048 ! response to peptide hormone stimulus GO:0043434 129 64 0,000 0,0213976 0,02313024 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,02172858 0,02347763 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,02172858 0,02346725 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,02172858 0,02345688 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,02172858 0,02344652 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,02172858 0,02343617 ! positive regulation of cell motion GO:0051272 157 65 0,000 0,02172858 0,02342583 ! ear development GO:0043583 114 66 0,000 0,02205946 0,02377206 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,02205946 0,02376158 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,02205946 0,02375111 ! gonad development GO:0008406 115 66 0,000 0,02205946 0,02374065 ! steroid hormone receptor signaling pathway GO:0030518 146 66 0,000 0,02205946 0,02373019 ! negative regulation of cell growth GO:0030308 142 67 0,000 0,02239024 0,02407542 ! activation of MAPK activity GO:0000187 124 67 0,000 0,02239024 0,02406483 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,02239024 0,02405424 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 0,000 0,02239024 0,02404367 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,02239024 0,02403311 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,02239024 0,02402255 ! secondary metabolic process GO:0019748 125 67 0,000 0,02239024 0,02401201 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,02239024 0,02400147 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,02272091 0,02434526 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,02272091 0,02433458 ! hexose catabolic process GO:0019320 113 68 0,000 0,02272091 0,02432392 ! extracellular matrix organization GO:0030198 146 68 0,000 0,02272091 0,02431327 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,02272091 0,02430262 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,02272091 0,02429199 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,02272091 0,02428136 ! viral reproduction GO:0016032 142 68 0,000 0,02272091 0,02427074 ! regulation of lipase activity GO:0060191 137 68 0,000 0,02272091 0,02426013 ! adaptive immune response GO:0002250 126 68 0,000 0,02272091 0,02424954 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cell projection assembly GO:0030031 138 68 0,000 0,02272091 0,02423895 ! negative regulation of cell size GO:0045792 144 69 0,000 0,02305148 0,02458087 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,02305148 0,02457015 ! negative regulation of protein kinase activity GO:0006469 144 69 0,000 0,02305148 0,02455943 ! lung development GO:0030324 165 69 0,000 0,02305148 0,02454872 ! urogenital system development GO:0001655 149 69 0,000 0,02305148 0,02453803 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 0,000 0,02305148 0,02452734 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,02305148 0,02451666 ! developmental maturation GO:0021700 128 69 0,000 0,02305148 0,02450599 ! single fertilization GO:0007338 83 69 0,000 0,02305148 0,02449533 ! negative regulation of kinase activity GO:0033673 145 70 0,000 0,02338195 0,0248357 ! cell redox homeostasis GO:0045454 114 70 0,000 0,02338195 0,02482491 ! germ cell development GO:0007281 133 70 0,000 0,02338195 0,02481412 ! activation of immune response GO:0002253 120 70 0,000 0,02338195 0,02480335 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,02338195 0,02479258 ! cell cycle checkpoint GO:0000075 145 71 0,000 0,02371232 0,02513197 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,02371232 0,02512107 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,02371232 0,02511018 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 0,000 0,02371232 0,0250993 ! appendage morphogenesis GO:0035107 150 72 0,000 0,02404258 0,02543786 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,02404258 0,02542685 ! respiratory tube development GO:0030323 171 72 0,000 0,02404258 0,02541585 ! actin filament organization GO:0007015 167 72 0,000 0,02404258 0,02540486 ! B cell activation GO:0042113 179 72 0,000 0,02404258 0,02539387 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,02404258 0,0253829 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,02404258 0,02537193 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,02404258 0,02536098 ! appendage development GO:0048736 151 73 0,000 0,02437274 0,02569815 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,02437274 0,02568706 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,02437274 0,02567599 ! regulation of immune effector process GO:0002697 156 73 0,000 0,02437274 0,02566492 ! acute inflammatory response GO:0002526 118 74 0,000 0,0247028 0,02600127 ! amino acid transport GO:0006865 148 74 0,000 0,0247028 0,02599007 ! regulation of caspase activity GO:0043281 136 74 0,000 0,0247028 0,02597888 ! negative regulation of transferase activity GO:0051348 155 74 0,000 0,0247028 0,02596771 ! respiratory system development GO:0060541 175 74 0,000 0,0247028 0,02595654 ! organelle localization GO:0051640 155 74 0,000 0,0247028 0,02594538 ! regulation of transcription factor activity GO:0051090 137 75 0,000 0,02503276 0,02628063 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 143 75 0,000 0,02503276 0,02626934 ! reproductive structure development GO:0048608 131 75 0,000 0,02503276 0,02625806 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,02503276 0,02624679 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,02503276 0,02623553 ! eye development GO:0001654 155 75 0,000 0,02503276 0,02622428 ! axon guidance GO:0007411 162 75 0,000 0,02503276 0,02621304 ! rhythmic process GO:0048511 142 75 0,000 0,02503276 0,02620181 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,02536261 0,0265357 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,02536261 0,02652434 ! learning or memory GO:0007611 161 76 0,000 0,02536261 0,02651299 ! regulation of blood pressure GO:0008217 134 76 0,000 0,02536261 0,02650165 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,02536261 0,02649032 ! amine catabolic process GO:0009310 136 77 0,000 0,02569237 0,02682327 ! neurotransmitter transport GO:0006836 142 77 0,000 0,02569237 0,02681181 ! phosphoinositide metabolic process GO:0030384 146 77 0,000 0,02569237 0,02680036 ! regulation of endopeptidase activity GO:0052548 141 77 0,000 0,02569237 0,02678892 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,02569237 0,0267775 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,02569237 0,02676608 ! regulation of catabolic process GO:0009894 173 77 0,000 0,02569237 0,02675467 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,02602202 0,0270864 ! antigen processing and presentation GO:0019882 117 78 0,000 0,02602202 0,02707487 ! fertilization GO:0009566 99 78 0,000 0,02602202 0,02706334 ! positive regulation of lymphocyte activation GO:0051251 142 78 0,000 0,02602202 0,02705182 ! blood coagulation GO:0007596 151 79 0,000 0,02635156 0,02738276 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,02635156 0,02737112 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,02635156 0,02735949 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,02635156 0,02734786 ! protein oligomerization GO:0051259 149 79 0,000 0,02635156 0,02733625 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,02635156 0,02732465 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,02668101 0,02765452 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,02668101 0,02764279 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,02668101 0,02763107 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,02668101 0,02761937 ! meiosis GO:0007126 143 81 0,000 0,02701035 0,02794845 GO:0051327|M phase of meiotic cell cycle, ! muscle cell differentiation GO:0042692 178 81 0,000 0,02701035 0,02793662 ! response to hypoxia GO:0001666 178 81 0,000 0,02701035 0,0279248 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,02701035 0,02791298 ! regulation of peptidase activity GO:0052547 150 82 0,000 0,02733959 0,02824128 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,02733959 0,02822934 ! protein import into nucleus GO:0006606 174 82 0,000 0,02733959 0,02821742 ! meiotic cell cycle GO:0051321 144 82 0,000 0,02733959 0,0282055 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,02766873 0,02853302 ! exocytosis GO:0006887 153 83 0,000 0,02766873 0,02852098 ! response to drug GO:0042493 149 83 0,000 0,02766873 0,02850895 ! response to oxygen levels GO:0070482 183 83 0,000 0,02766873 0,02849693 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,02766873 0,02848492 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,02766873 0,02847292 ! nuclear import GO:0051170 177 83 0,000 0,02766873 0,02846093 ! inorganic anion transport GO:0015698 156 83 0,000 0,02766873 0,02844895 ! T cell activation GO:0042110 189 84 0,000 0,02799777 0,02877516 ! response to nutrient GO:0007584 135 84 0,000 0,02799777 0,02876306 ! digestion GO:0007586 130 84 0,000 0,02799777 0,02875097 ! hemostasis GO:0007599 165 85 0,000 0,0283267 0,02907653 ! negative regulation of transport GO:0051051 164 85 0,000 0,0283267 0,02906432 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,0283267 0,02905211 ! negative regulation of growth GO:0045926 168 85 0,000 0,0283267 0,02903992 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,0283267 0,02902774 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,0283267 0,02901557 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,0283267 0,02900341 ! cellular response to hormone stimulus GO:0032870 182 85 0,000 0,0283267 0,02899126 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,02865554 0,02931553 ! regulation of lyase activity GO:0051339 169 86 0,000 0,02865554 0,02930325 ! positive regulation of cell activation GO:0050867 161 86 0,000 0,02865554 0,02929099 GO:0002696|positive regulation of leukocyte activation, ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,02898427 0,02961462 ! mitochondrion organization GO:0007005 159 87 0,000 0,02898427 0,02960224 ! alcohol catabolic process GO:0046164 142 87 0,000 0,02898427 0,02958987 ! nucleosome assembly GO:0006334 126 87 0,000 0,02898427 0,02957751 ! regulation of protein transport GO:0051223 165 87 0,000 0,02898427 0,02956516 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 143 88 0,000 0,0293129 0,0298879 ! amine biosynthetic process GO:0009309 146 88 0,000 0,0293129 0,02987543 ! sensory perception of smell GO:0007608 117 88 0,000 0,0293129 0,02986297 ! chromatin assembly GO:0031497 128 88 0,000 0,0293129 0,02985052 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,0293129 0,02983809 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,02964142 0,03015993 ! regulation of DNA binding GO:0051101 167 89 0,000 0,02964142 0,03014738 ! tube morphogenesis GO:0035239 194 89 0,000 0,02964142 0,03013483 ! cellular defense response GO:0006968 123 89 0,000 0,02964142 0,03012229 ! protein localization in nucleus GO:0034504 192 89 0,000 0,02964142 0,03010977 ! regulation of neurological system process GO:0031644 175 89 0,000 0,02964142 0,03009726 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,02996985 0,03041809 ! regulation of cell cycle process GO:0010564 161 90 0,000 0,02996985 0,03040546 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,03029817 0,03072579 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! ossification GO:0001503 205 91 0,000 0,03029817 0,03071304 ! gland development GO:0048732 220 91 0,000 0,03029817 0,0307003 ! defense response to bacterium GO:0042742 112 91 0,000 0,03029817 0,03068758 ! bone development GO:0060348 206 92 0,000 0,03062639 0,03100716 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,03062639 0,03099431 ! regulation of cell adhesion GO:0030155 241 92 0,000 0,03062639 0,03098148 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,03095451 0,03130044 ! amine transport GO:0015837 181 93 0,000 0,03095451 0,03128749 ! positive regulation of MAP kinase activity GO:0043406 174 93 0,000 0,03095451 0,03127455 ! vitamin metabolic process GO:0006766 153 93 0,000 0,03095451 0,03126162 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,03128253 0,03157984 ! female pregnancy GO:0007565 166 94 0,000 0,03128253 0,0315668 ! sterol metabolic process GO:0016125 166 94 0,000 0,03128253 0,03155376 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,03128253 0,03154074 ! regulation of membrane potential GO:0042391 179 94 0,000 0,03128253 0,03152773 ! regulation of defense response GO:0031347 171 95 0,000 0,03161044 0,03184508 ! nucleosome organization GO:0034728 143 95 0,000 0,03161044 0,03183195 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,03161044 0,03181884 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,03161044 0,03180573 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,03161044 0,03179264 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,03161044 0,03177955 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,03161044 0,03176648 ! sex differentiation GO:0007548 171 96 0,000 0,03193826 0,03208272 ! regulation of T cell activation GO:0050863 175 96 0,000 0,03193826 0,03206953 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,03226597 0,03238528 ! transcription initiation GO:0006352 171 97 0,000 0,03226597 0,03237198 ! regulation of protein localization GO:0032880 188 97 0,000 0,03226597 0,03235869 ! leukocyte differentiation GO:0002521 232 98 0,000 0,03259358 0,03267383 ! forebrain development GO:0030900 210 98 0,000 0,03259358 0,03266043 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,03259358 0,03264703 ! skeletal muscle tissue development GO:0007519 223 100 0,000 0,0332485 0,03328938 GO:0060538|skeletal muscle organ development, ! mRNA transport GO:0051028 185 100 0,000 0,0332485 0,03327574 ! positive regulation of immune response GO:0050778 175 100 0,000 0,0332485 0,03326211 ! hormone metabolic process GO:0042445 171 100 0,000 0,0332485 0,0332485