pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-b2/out-0.05-06-0.01-300-run-b2//th1-pval-1e-01-06-th2-pval-1e-02-02-th3-pval-1e-01-01-run-b2/go_data/836-9-real-Sotiriou-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! positive regulation of cell cycle GO:0045787 77 45 2,000 2,592E-06 5,962E-03 ! response to UV GO:0009411 75 46 2,000 2,772E-06 3,188E-03 ! induction of apoptosis by oxidative stress GO:0008631 5 5 1,000 3,596E-06 2,757E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 2,000 3,796E-06 2,183E-03 ! neuron apoptosis GO:0051402 8 6 1,000 5,392E-06 2,48E-03 ! spindle checkpoint GO:0031577 14 6 1,000 5,392E-06 2,067E-03 ! establishment of chromosome localization GO:0051303 9 6 1,000 5,392E-06 1,772E-03 GO:0050000|chromosome localization, ! negative regulation of B cell activation GO:0050869 9 6 1,000 5,392E-06 1,55E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 7,546E-06 1,928E-03 ! positive regulation of mitotic cell cycle GO:0045931 11 7 1,000 7,546E-06 1,736E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 1,000 1,006E-05 2,103E-03 ! regulation of activated T cell proliferation GO:0046006 15 9 1,000 1,293E-05 2,478E-03 ! regulation of exit from mitosis GO:0007096 12 9 1,000 1,293E-05 2,287E-03 ! regulation of B cell proliferation GO:0030888 15 10 1,000 1,615E-05 2,654E-03 ! interphase of mitotic cell cycle GO:0051329 156 86 2,000 1,843E-05 2,826E-03 ! double-strand break repair via homologous recombination GO:0000724 16 11 1,000 1,974E-05 2,837E-03 GO:0000725|recombinational repair, ! T cell homeostasis GO:0043029 20 11 1,000 1,974E-05 2,67E-03 ! negative regulation of mast cell proliferation GO:0070667 17 11 1,000 1,974E-05 2,522E-03 GO:0042130|negative regulation of T cell proliferation, ! interphase GO:0051325 159 88 2,000 1,975E-05 2,391E-03 ! response to light stimulus GO:0009416 153 96 2,000 2,565E-05 2,949E-03 ! induction of apoptosis via death domain receptors GO:0008625 15 13 1,000 2,797E-05 3,063E-03 ! lymphocyte homeostasis GO:0002260 24 13 1,000 2,797E-05 2,924E-03 ! negative regulation of caspase activity GO:0043154 20 14 1,000 3,262E-05 3,262E-03 ! DNA unwinding during replication GO:0006268 21 14 1,000 3,262E-05 3,126E-03 ! release of cytochrome c from mitochondria GO:0001836 23 14 1,000 3,262E-05 3,001E-03 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 1,000 3,763E-05 3,328E-03 ! negative regulation of leukocyte proliferation GO:0070664 25 15 1,000 3,763E-05 3,205E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! cellular response to unfolded protein GO:0034620 19 16 1,000 4,299E-05 3,531E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! negative regulation of peptidase activity GO:0010466 23 17 1,000 4,87E-05 3,862E-03 ! DNA duplex unwinding GO:0032508 25 17 1,000 4,87E-05 3,734E-03 GO:0032392|DNA geometric change, ! apoptotic mitochondrial changes GO:0008637 29 18 1,000 5,477E-05 4,064E-03 ! negative regulation of T cell activation GO:0050868 25 18 1,000 5,477E-05 3,937E-03 ! reciprocal meiotic recombination GO:0007131 31 19 1,000 6,119E-05 4,265E-03 ! cell structure disassembly during apoptosis GO:0006921 24 19 1,000 6,119E-05 4,139E-03 ! apoptotic nuclear changes GO:0030262 24 19 1,000 6,119E-05 4,021E-03 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 1,000 7,51E-05 4,798E-03 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 1,000 7,51E-05 4,668E-03 ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 7,51E-05 4,545E-03 ! leukocyte homeostasis GO:0001776 33 22 1,000 8,258E-05 4,87E-03 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 9,041E-05 5,199E-03 ! fat cell differentiation GO:0045444 37 24 1,000 9,86E-05 5,531E-03 ! positive regulation of nuclear division GO:0051785 39 25 1,000 1,071E-04 5,867E-03 GO:0045840|positive regulation of mitosis, ! negative regulation of lymphocyte activation GO:0051250 37 25 1,000 1,071E-04 5,73E-03 ! negative regulation of leukocyte activation GO:0002695 39 27 1,000 1,253E-04 6,548E-03 ! regulation of B cell activation GO:0050864 42 28 1,000 1,348E-04 6,892E-03 ! negative regulation of cell activation GO:0050866 44 30 1,000 1,551E-04 7,754E-03 ! meiosis I GO:0007127 52 32 1,000 1,767E-04 8,647E-03 ! positive regulation of DNA metabolic process GO:0051054 54 33 1,000 1,88E-04 9,01E-03 ! nucleus organization GO:0006997 49 33 1,000 1,88E-04 8,826E-03 ! negative regulation of hydrolase activity GO:0051346 50 33 1,000 1,88E-04 8,65E-03 ! cytokinesis GO:0000910 52 33 1,000 1,88E-04 8,48E-03 ! keratinocyte differentiation GO:0030216 47 35 1,000 2,118E-04 9,366E-03 ! protein homooligomerization GO:0051260 52 35 1,000 2,118E-04 9,189E-03 ! regulation of T cell proliferation GO:0042129 58 38 1,000 2,499E-04 0,01064528 ! response to calcium ion GO:0051592 58 40 1,000 2,771E-04 0,01158856 ! induction of apoptosis by intracellular signals GO:0008629 67 40 1,000 2,771E-04 0,01138162 ! double-strand break repair GO:0006302 67 40 1,000 2,771E-04 0,01118194 ! epidermal cell differentiation GO:0009913 53 40 1,000 2,771E-04 0,01098915 ! cellular component disassembly GO:0022411 64 42 1,000 3,057E-04 0,01191655 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 1,000 3,205E-04 0,01228533 ! DNA-dependent DNA replication GO:0006261 59 43 1,000 3,205E-04 0,01208393 ! induction of apoptosis by extracellular signals GO:0008624 74 44 1,000 3,356E-04 0,01245089 ! regulation of mast cell proliferation GO:0070666 64 44 1,000 3,356E-04 0,01225326 ! negative regulation of immune system process GO:0002683 73 47 1,000 3,831E-04 0,01376891 ! regulation of leukocyte proliferation GO:0070663 71 47 1,000 3,831E-04 0,01355708 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! positive regulation of organelle organization GO:0010638 82 51 1,000 4,513E-04 0,0157262 ! establishment of organelle localization GO:0051656 85 52 1,000 4,692E-04 0,0161056 ! regulation of mitosis GO:0007088 84 54 1,000 5,06E-04 0,01711358 GO:0051783|regulation of nuclear division, ! DNA catabolic process GO:0006308 67 54 1,000 5,06E-04 0,01686556 ! negative regulation of protein kinase activity GO:0006469 99 57 1,000 5,637E-04 0,01852242 ! negative regulation of kinase activity GO:0033673 100 58 1,000 5,837E-04 0,01890724 ! meiosis GO:0007126 96 61 1,000 6,455E-04 0,02061983 GO:0051327|M phase of meiotic cell cycle, ! homeostasis of number of cells GO:0048872 84 61 1,000 6,455E-04 0,02033737 ! negative regulation of transferase activity GO:0051348 105 61 1,000 6,455E-04 0,02006254 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 1,000 6,455E-04 0,01979504 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 1,000 6,668E-04 0,0201788 ! meiotic cell cycle GO:0051321 97 62 1,000 6,668E-04 0,01991674 ! organelle localization GO:0051640 96 62 1,000 6,668E-04 0,01966139 ! cell cycle checkpoint GO:0000075 108 64 1,000 7,104E-04 0,02068153 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 1,000 7,104E-04 0,02042301 ! regulation of caspase activity GO:0043281 97 65 1,000 7,327E-04 0,02080407 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 1,000 7,327E-04 0,02055037 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 1,000 7,327E-04 0,02030277 ! protein oligomerization GO:0051259 100 65 1,000 7,327E-04 0,02006107 ! regulation of endopeptidase activity GO:0052548 99 67 1,000 7,783E-04 0,02105919 ! positive regulation of ligase activity GO:0051351 99 69 1,000 8,252E-04 0,02207005 ! response to metal ion GO:0010038 103 70 1,000 8,492E-04 0,02245032 ! positive regulation of phosphorylation GO:0042327 102 70 1,000 8,492E-04 0,0221952 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 1,000 8,735E-04 0,02257418 ! regulation of peptidase activity GO:0052547 106 72 1,000 8,982E-04 0,02295328 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 1,000 8,982E-04 0,02270105 GO:0045937|positive regulation of phosphate metabolic process, ! mitochondrion organization GO:0007005 104 73 1,000 9,232E-04 0,02307889 ! response to inorganic substance GO:0010035 115 75 1,000 9,741E-04 0,02409124 ! regulation of ligase activity GO:0051340 114 75 1,000 9,741E-04 0,02383495 ! response to unfolded protein GO:0006986 99 76 1,000 1E-03 0,02421315 ! positive regulation of protein modification process GO:0031401 107 78 1,000 1,053E-03 0,02522992 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 1,000 1,107E-03 0,02625724 GO:0010498|proteasomal protein catabolic process, ! regulation of cell cycle process GO:0010564 122 81 1,000 1,135E-03 0,02663812 ! response to protein stimulus GO:0051789 111 81 1,000 1,135E-03 0,02636904 ! regulation of DNA metabolic process GO:0051052 135 85 1,000 1,249E-03 0,02872476 ! regulation of T cell activation GO:0050863 128 89 1,000 1,368E-03 0,03115395 ! cell fate commitment GO:0045165 141 92 1,000 1,461E-03 0,03294152 ! DNA recombination GO:0006310 146 92 1,000 1,461E-03 0,0326217 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 3,142E-03 0,0694975 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 3,142E-03 0,06883562 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 3,142E-03 0,06818622 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 3,142E-03 0,06754897 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 3,142E-03 0,06692352 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 3,142E-03 0,06630954 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 3,142E-03 0,06570672 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 3,142E-03 0,06511477 ! sleep GO:0030431 11 5 0,000 3,142E-03 0,06453339 ! negative regulation of bone resorption GO:0045779 10 5 0,000 3,142E-03 0,0639623 ! nucleotide-sugar transport GO:0015780 8 5 0,000 3,142E-03 0,06340123 ! regulation of interferon-beta production GO:0032648 5 5 0,000 3,142E-03 0,06284991 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 3,142E-03 0,0623081 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 3,142E-03 0,06177555 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 3,142E-03 0,06125203 ! tongue development GO:0043586 6 5 0,000 3,142E-03 0,06073731 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 3,142E-03 0,06023116 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 3,142E-03 0,05973339 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 3,142E-03 0,05924377 ! cobalt ion transport GO:0006824 9 5 0,000 3,142E-03 0,05876211 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 3,142E-03 0,05828822 ! SMAD protein complex assembly GO:0007183 9 5 0,000 3,142E-03 0,05782192 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 3,142E-03 0,05736301 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 3,142E-03 0,05691134 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 3,142E-03 0,05646672 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 3,142E-03 0,05602899 ! embryonic camera-type eye development GO:0031076 8 5 0,000 3,142E-03 0,055598 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 3,142E-03 0,05517359 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 3,142E-03 0,0547556 ! adaptation of signaling pathway GO:0022401 7 5 0,000 3,142E-03 0,05434391 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 3,142E-03 0,05393836 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 3,142E-03 0,05353881 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 3,142E-03 0,05314515 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 3,142E-03 0,05275722 ! positive regulation of histone modification GO:0031058 5 5 0,000 3,142E-03 0,05237493 ! malate metabolic process GO:0006108 7 5 0,000 3,142E-03 0,05199813 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 3,142E-03 0,05162671 ! behavioral response to pain GO:0048266 7 5 0,000 3,142E-03 0,05126057 ! clathrin coat assembly GO:0048268 11 5 0,000 3,142E-03 0,05089958 ! phototransduction, visible light GO:0007603 6 5 0,000 3,142E-03 0,05054363 ! regulation of dopamine uptake GO:0051584 9 5 0,000 3,142E-03 0,05019264 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 3,142E-03 0,04984648 ! mating behavior GO:0007617 6 5 0,000 3,142E-03 0,04950507 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 3,142E-03 0,0491683 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 3,142E-03 0,04883608 ! rhythmic behavior GO:0007622 12 5 0,000 3,142E-03 0,04850832 ! copulation GO:0007620 7 5 0,000 3,142E-03 0,04818493 ! glial cell fate commitment GO:0021781 12 5 0,000 3,142E-03 0,04786583 ! protein maturation by protein folding GO:0022417 12 5 0,000 3,142E-03 0,04755092 ! embryonic hemopoiesis GO:0035162 10 5 0,000 3,142E-03 0,04724013 ! regulation of potassium ion transport GO:0043266 9 5 0,000 3,142E-03 0,04693337 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 3,142E-03 0,04663058 ! apoptotic cell clearance GO:0043277 13 5 0,000 3,142E-03 0,04633166 ! lipoprotein particle clearance GO:0034381 9 5 0,000 3,142E-03 0,04603656 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 3,142E-03 0,04574519 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 3,142E-03 0,04545748 ! response to protozoan GO:0001562 9 5 0,000 3,142E-03 0,04517337 ! positive regulation of glycolysis GO:0045821 11 5 0,000 3,142E-03 0,04489279 ! lymph vessel development GO:0001945 7 5 0,000 3,142E-03 0,04461568 ! endochondral ossification GO:0001958 12 5 0,000 3,142E-03 0,04434196 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 3,142E-03 0,04407158 ! parathyroid gland development GO:0060017 8 5 0,000 3,142E-03 0,04380448 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 3,142E-03 0,0435406 ! anagen GO:0042640 6 5 0,000 3,142E-03 0,04327988 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 3,142E-03 0,04302226 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 3,142E-03 0,04276769 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 3,142E-03 0,04251612 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 3,142E-03 0,04226748 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 3,142E-03 0,04202174 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 3,142E-03 0,04177884 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 3,142E-03 0,04153873 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 3,142E-03 0,04130137 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 3,142E-03 0,0410667 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 3,142E-03 0,04083469 ! cardiac muscle fiber development GO:0048739 7 5 0,000 3,142E-03 0,04060528 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 3,142E-03 0,04037843 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 3,142E-03 0,04015411 ! neutrophil mediated immunity GO:0002446 6 5 0,000 3,142E-03 0,03993226 ! ovulation GO:0030728 6 5 0,000 3,142E-03 0,03971286 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 3,142E-03 0,03949585 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 3,142E-03 0,03928119 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 3,142E-03 0,03906886 ! response to pH GO:0009268 9 5 0,000 3,142E-03 0,03885882 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 3,142E-03 0,03865101 ! proline biosynthetic process GO:0006561 6 5 0,000 3,142E-03 0,03844542 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 3,142E-03 0,03824201 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 3,142E-03 0,03804074 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 3,142E-03 0,03784157 ! polyol catabolic process GO:0046174 7 5 0,000 3,142E-03 0,03764448 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 3,142E-03 0,03744943 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 3,142E-03 0,03725639 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 3,142E-03 0,03706533 ! sister chromatid cohesion GO:0007062 9 5 0,000 3,142E-03 0,03687622 ! nerve growth factor processing GO:0032455 7 5 0,000 3,142E-03 0,03668903 ! urea metabolic process GO:0019627 6 5 0,000 3,142E-03 0,03650374 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 3,142E-03 0,0363203 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 3,142E-03 0,0361387 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 3,142E-03 0,0359589 ! neutrophil activation GO:0042119 5 5 0,000 3,142E-03 0,03578089 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 3,142E-03 0,03560463 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 3,142E-03 0,0354301 ! response to food GO:0032094 5 5 0,000 3,142E-03 0,03525727 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 3,142E-03 0,03508612 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 3,142E-03 0,03491662 ! paraxial mesoderm development GO:0048339 9 5 0,000 3,142E-03 0,03474875 ! forebrain neuron development GO:0021884 7 5 0,000 3,142E-03 0,03458249 ! melanosome organization GO:0032438 7 5 0,000 3,142E-03 0,03441781 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 3,142E-03 0,03425469 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 3,142E-03 0,03409311 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 3,142E-03 0,03393305 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 3,142E-03 0,03377448 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 3,142E-03 0,03361739 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 3,142E-03 0,03346176 ! nucleoside transport GO:0015858 6 5 0,000 3,142E-03 0,03330756 ! nucleoside salvage GO:0043174 7 5 0,000 3,142E-03 0,03315477 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 3,142E-03 0,03300338 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 3,142E-03 0,03285336 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 3,142E-03 0,0327047 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 3,142E-03 0,03255739 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 3,142E-03 0,03241139 ! early endosome to late endosome transport GO:0045022 11 5 0,000 3,142E-03 0,0322667 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 3,142E-03 0,03212329 ! depyrimidination GO:0045008 8 5 0,000 3,142E-03 0,03198115 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 3,142E-03 0,03184026 ! 5S class rRNA transcription GO:0042791 8 5 0,000 3,142E-03 0,03170061 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 3,142E-03 0,03156218 ! regulation of centrosome cycle GO:0046605 7 5 0,000 3,142E-03 0,03142496 ! neuronal ion channel clustering GO:0045161 7 5 0,000 3,142E-03 0,03128892 ! sodium ion homeostasis GO:0055078 6 5 0,000 3,142E-03 0,03115405 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 3,142E-03 0,03102034 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 3,142E-03 0,03088778 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 3,142E-03 0,03075634 ! monocyte differentiation GO:0030224 8 5 0,000 3,142E-03 0,03062602 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 3,142E-03 0,03049679 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 3,142E-03 0,03036865 ! centrosome duplication GO:0051298 5 5 0,000 3,142E-03 0,03024159 ! response to UV-C GO:0010225 6 5 0,000 3,142E-03 0,03011558 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 3,142E-03 0,02999062 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 3,142E-03 0,02986669 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 3,142E-03 0,02974378 ! regulation of dendrite development GO:0050773 12 5 0,000 3,142E-03 0,02962188 ! peptidyl-arginine modification GO:0018195 7 5 0,000 3,142E-03 0,02950098 ! positive regulation of organ growth GO:0046622 6 5 0,000 3,142E-03 0,02938106 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 3,142E-03 0,0292621 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 3,142E-03 0,02914411 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 3,142E-03 0,02902707 ! regulation of dopamine secretion GO:0014059 12 5 0,000 3,142E-03 0,02891096 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 3,142E-03 0,02879578 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 3,142E-03 0,02868151 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 3,142E-03 0,02856814 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 3,142E-03 0,02845567 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 3,142E-03 0,02834408 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 3,142E-03 0,02823336 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 3,142E-03 0,0281235 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 3,142E-03 0,0280145 ! neural tube patterning GO:0021532 6 5 0,000 3,142E-03 0,02790633 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 3,142E-03 0,027799 ! histone demethylation GO:0016577 9 5 0,000 3,142E-03 0,02769249 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 3,142E-03 0,02758679 ! regulation of sterol transport GO:0032371 7 5 0,000 3,142E-03 0,0274819 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 3,142E-03 0,0273778 ! enteric nervous system development GO:0048484 8 5 0,000 3,142E-03 0,02727449 ! establishment of planar polarity GO:0001736 6 5 0,000 3,142E-03 0,02717195 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 3,142E-03 0,02707019 ! muscle cell proliferation GO:0033002 8 5 0,000 3,142E-03 0,02696918 ! transcription termination GO:0006353 8 5 0,000 3,142E-03 0,02686892 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 3,142E-03 0,02676941 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 3,142E-03 0,02667063 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 3,142E-03 0,02657257 ! regulation of respiratory burst GO:0060263 8 5 0,000 3,142E-03 0,02647524 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 3,142E-03 0,02637861 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 3,142E-03 0,02628269 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 3,142E-03 0,02618746 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 3,142E-03 0,02609292 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 3,142E-03 0,02599906 ! apical protein localization GO:0045176 6 5 0,000 3,142E-03 0,02590588 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 3,142E-03 0,02581336 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 3,142E-03 0,02572149 ! galactolipid metabolic process GO:0019374 7 5 0,000 3,142E-03 0,02563028 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 3,142E-03 0,02553972 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 3,142E-03 0,02544979 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 3,142E-03 0,02536049 ! triglyceride catabolic process GO:0019433 6 5 0,000 3,142E-03 0,02527182 ! glial cell migration GO:0008347 10 5 0,000 3,142E-03 0,02518376 ! determination of adult lifespan GO:0008340 8 5 0,000 3,142E-03 0,02509632 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 3,142E-03 0,02500948 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 3,142E-03 0,02492324 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 3,142E-03 0,02483759 ! somatic stem cell maintenance GO:0035019 13 5 0,000 3,142E-03 0,02475253 ! cerebellar cortex formation GO:0021697 6 5 0,000 3,142E-03 0,02466805 ! neural plate development GO:0001840 6 5 0,000 3,142E-03 0,02458415 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 3,142E-03 0,02450081 ! regulation of sensory perception GO:0051931 6 5 0,000 3,142E-03 0,02441804 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 3,142E-03 0,02433582 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 3,142E-03 0,02425416 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 3,142E-03 0,02417304 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 3,142E-03 0,02409247 ! sensory cilium assembly GO:0035058 6 5 0,000 3,142E-03 0,02401242 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 3,142E-03 0,02393291 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 3,142E-03 0,02385393 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 3,142E-03 0,02377546 ! spindle assembly GO:0051225 5 5 0,000 3,142E-03 0,02369751 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 3,142E-03 0,02362006 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 3,142E-03 0,02354313 ! protein amino acid prenylation GO:0018346 9 5 0,000 3,142E-03 0,02346669 ! organ regeneration GO:0031100 7 5 0,000 3,142E-03 0,02339074 ! NAD biosynthetic process GO:0009435 7 5 0,000 3,142E-03 0,02331529 ! carnitine metabolic process GO:0009437 5 5 0,000 3,142E-03 0,02324032 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 3,142E-03 0,02316583 ! cellular anion homeostasis GO:0030002 6 5 0,000 3,142E-03 0,02309182 GO:0055081|anion homeostasis, ! tRNA transcription GO:0009304 11 6 0,000 3,77E-03 0,02761404 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 3,77E-03 0,02752637 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 3,77E-03 0,02743926 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 3,77E-03 0,0273527 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 3,77E-03 0,02726669 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 3,77E-03 0,02718121 ! regulation of helicase activity GO:0051095 11 6 0,000 3,77E-03 0,02709627 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 3,77E-03 0,02701186 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 3,77E-03 0,02692797 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 3,77E-03 0,02684461 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 3,77E-03 0,02676175 ! positive regulation of axon extension GO:0045773 8 6 0,000 3,77E-03 0,02667941 ! prostate gland development GO:0030850 9 6 0,000 3,77E-03 0,02659757 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 3,77E-03 0,02651623 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 3,77E-03 0,02643539 ! forebrain neuron differentiation GO:0021879 9 6 0,000 3,77E-03 0,02635504 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 3,77E-03 0,02627517 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 3,77E-03 0,02619579 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 3,77E-03 0,02611689 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 3,77E-03 0,02603846 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 3,77E-03 0,0259605 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 3,77E-03 0,02588301 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 3,77E-03 0,02580597 ! neuron adhesion GO:0007158 9 6 0,000 3,77E-03 0,0257294 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 3,77E-03 0,02565328 ! establishment of tissue polarity GO:0007164 7 6 0,000 3,77E-03 0,0255776 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 3,77E-03 0,02550237 ! signal peptide processing GO:0006465 8 6 0,000 3,77E-03 0,02542759 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 3,77E-03 0,02535324 ! mRNA stabilization GO:0048255 15 6 0,000 3,77E-03 0,02527932 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 3,77E-03 0,02520584 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 3,77E-03 0,02513278 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 3,77E-03 0,02506014 ! opsonization GO:0008228 8 6 0,000 3,77E-03 0,02498792 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 3,77E-03 0,02491611 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 3,77E-03 0,02484472 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 3,77E-03 0,02477374 ! protein amino acid dealkylation GO:0008214 11 6 0,000 3,77E-03 0,02470316 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 3,77E-03 0,02463298 ! photoreceptor cell development GO:0042461 10 6 0,000 3,77E-03 0,02456319 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 3,77E-03 0,02449381 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 3,77E-03 0,02442481 ! mechanosensory behavior GO:0007638 8 6 0,000 3,77E-03 0,0243562 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 3,77E-03 0,02428798 ! negative regulation of endocytosis GO:0045806 8 6 0,000 3,77E-03 0,02422013 ! response to interferon-gamma GO:0034341 12 6 0,000 3,77E-03 0,02415267 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 3,77E-03 0,02408558 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 3,77E-03 0,02401886 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 3,77E-03 0,02395251 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 3,77E-03 0,02388652 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 3,77E-03 0,0238209 ! cGMP-mediated signaling GO:0019934 10 6 0,000 3,77E-03 0,02375564 ! activation of MAPKKK activity GO:0000185 10 6 0,000 3,77E-03 0,02369073 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 3,77E-03 0,02362618 ! thymic T cell selection GO:0045061 12 6 0,000 3,77E-03 0,02356198 ! protein lipoylation GO:0009249 10 6 0,000 3,77E-03 0,02349812 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 3,77E-03 0,02343461 ! pigment granule organization GO:0048753 11 6 0,000 3,77E-03 0,02337145 ! drug transport GO:0015893 6 6 0,000 3,77E-03 0,02330862 ! cysteine metabolic process GO:0006534 7 6 0,000 3,77E-03 0,02324613 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 3,77E-03 0,02318398 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 3,77E-03 0,02312215 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 3,77E-03 0,02306066 ! histidine metabolic process GO:0006547 6 6 0,000 3,77E-03 0,02299949 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 3,77E-03 0,02293864 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 3,77E-03 0,02287812 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 3,77E-03 0,02281791 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 3,77E-03 0,02275802 ! adenohypophysis development GO:0021984 10 6 0,000 3,77E-03 0,02269845 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 3,77E-03 0,02263918 ! hyperosmotic response GO:0006972 8 6 0,000 3,77E-03 0,02258023 ! microtubule nucleation GO:0007020 10 6 0,000 3,77E-03 0,02252158 ! ER overload response GO:0006983 7 6 0,000 3,77E-03 0,02246323 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 3,77E-03 0,02240519 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 3,77E-03 0,02234744 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 3,77E-03 0,02228999 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 3,77E-03 0,02223284 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 3,77E-03 0,02217598 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 3,77E-03 0,02211941 ! response to dietary excess GO:0002021 7 6 0,000 3,77E-03 0,02206312 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 3,77E-03 0,02200713 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 3,77E-03 0,02195141 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 3,77E-03 0,02189598 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 3,77E-03 0,02184082 ! glycerol ether catabolic process GO:0044269 8 6 0,000 3,77E-03 0,02178595 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 3,77E-03 0,02173135 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 3,77E-03 0,02167702 ! organic alcohol transport GO:0015850 9 6 0,000 3,77E-03 0,02162296 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 3,77E-03 0,02156917 ! T cell mediated immunity GO:0002456 12 6 0,000 3,77E-03 0,02151565 ! male sex determination GO:0030238 9 6 0,000 3,77E-03 0,02146239 ! carnitine transport GO:0015879 8 6 0,000 3,77E-03 0,0214094 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 3,77E-03 0,02135667 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 3,77E-03 0,0213042 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 3,77E-03 0,02125198 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 3,77E-03 0,02120002 ! positive regulation of exocytosis GO:0045921 6 6 0,000 3,77E-03 0,02114831 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 3,77E-03 0,02109686 ! parturition GO:0007567 12 6 0,000 3,77E-03 0,02104565 ! negative regulation of translational initiation GO:0045947 7 6 0,000 3,77E-03 0,02099469 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 3,77E-03 0,02094398 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 3,77E-03 0,02089351 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 3,77E-03 0,02084329 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! regulation of collagen metabolic process GO:0010712 7 6 0,000 3,77E-03 0,0207933 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 3,77E-03 0,02074356 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 3,77E-03 0,02069405 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 3,77E-03 0,02064478 ! macrophage differentiation GO:0030225 10 6 0,000 3,77E-03 0,02059574 ! astrocyte development GO:0014002 14 6 0,000 3,77E-03 0,02054694 ! hyaluronan metabolic process GO:0030212 6 6 0,000 3,77E-03 0,02049836 ! purine base biosynthetic process GO:0009113 14 6 0,000 3,77E-03 0,02045002 ! interaction with symbiont GO:0051702 8 6 0,000 3,77E-03 0,0204019 ! anterograde axon cargo transport GO:0008089 8 6 0,000 3,77E-03 0,02035401 ! skeletal muscle contraction GO:0003009 6 6 0,000 3,77E-03 0,02030634 ! eating behavior GO:0042755 6 6 0,000 3,77E-03 0,0202589 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 3,77E-03 0,02021167 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 3,77E-03 0,02016467 ! response to copper ion GO:0046688 9 6 0,000 3,77E-03 0,02011788 ! DNA topological change GO:0006265 8 6 0,000 3,77E-03 0,02007131 ! response to exogenous dsRNA GO:0043330 8 6 0,000 3,77E-03 0,02002496 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 3,77E-03 0,01997882 ! establishment of melanosome localization GO:0032401 9 6 0,000 3,77E-03 0,01993289 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 3,77E-03 0,01988717 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 3,77E-03 0,01984166 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 3,77E-03 0,01979636 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 3,77E-03 0,01975127 ! nucleoside catabolic process GO:0009164 6 6 0,000 3,77E-03 0,01970638 ! gas homeostasis GO:0033483 11 6 0,000 3,77E-03 0,01966169 ! hair follicle maturation GO:0048820 7 6 0,000 3,77E-03 0,01961721 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 3,77E-03 0,01957293 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 3,77E-03 0,01952885 ! Schwann cell development GO:0014044 14 6 0,000 3,77E-03 0,01948496 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 3,77E-03 0,01944127 ! dendrite morphogenesis GO:0048813 9 6 0,000 3,77E-03 0,01939778 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 3,77E-03 0,01935448 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 3,77E-03 0,01931138 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 3,77E-03 0,01926846 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 3,77E-03 0,01922574 ! histone ubiquitination GO:0016574 7 6 0,000 3,77E-03 0,0191832 ! regulation of meiosis GO:0040020 10 6 0,000 3,77E-03 0,01914086 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 3,77E-03 0,01909869 GO:0000085|G2 phase of mitotic cell cycle, ! regulation of cell division GO:0051302 8 6 0,000 3,77E-03 0,01905672 ! regulation of mast cell activation GO:0033003 6 6 0,000 3,77E-03 0,01901493 ! membrane to membrane docking GO:0022614 12 6 0,000 3,77E-03 0,01897332 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 3,77E-03 0,01893189 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 3,77E-03 0,01889065 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 3,77E-03 0,01884958 ! receptor internalization GO:0031623 9 6 0,000 3,77E-03 0,01880869 ! neutrophil homeostasis GO:0001780 6 6 0,000 3,77E-03 0,01876798 ! coenzyme A metabolic process GO:0015936 9 6 0,000 3,77E-03 0,01872745 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 3,77E-03 0,01868709 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 3,77E-03 0,0186469 ! protein deubiquitination GO:0016579 8 6 0,000 3,77E-03 0,01860688 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 3,77E-03 0,01856704 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 3,77E-03 0,01852737 ! peptidyl-histidine modification GO:0018202 9 6 0,000 3,77E-03 0,01848786 ! axonal fasciculation GO:0007413 9 6 0,000 3,77E-03 0,01844853 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 3,77E-03 0,01840936 ! thiamin metabolic process GO:0006772 6 6 0,000 3,77E-03 0,01837035 ! midbrain development GO:0030901 6 6 0,000 3,77E-03 0,01833152 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 3,77E-03 0,01829284 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 3,77E-03 0,01825433 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 3,77E-03 0,01821598 ! progesterone metabolic process GO:0042448 8 6 0,000 3,77E-03 0,01817779 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 3,77E-03 0,01813976 ! glycolipid catabolic process GO:0019377 13 6 0,000 3,77E-03 0,01810189 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 3,77E-03 0,01806418 ! positive regulation of glucose import GO:0046326 6 6 0,000 3,77E-03 0,01802663 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 3,77E-03 0,01798923 ! adult feeding behavior GO:0008343 6 6 0,000 3,77E-03 0,01795198 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 3,77E-03 0,01791489 ! blastocyst growth GO:0001832 15 6 0,000 3,77E-03 0,01787795 ! pigment granule transport GO:0051904 12 6 0,000 3,77E-03 0,01784117 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 3,77E-03 0,01780453 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 3,77E-03 0,01776805 ! catecholamine transport GO:0051937 7 6 0,000 3,77E-03 0,01773171 ! organ or tissue specific immune response GO:0002251 7 6 0,000 3,77E-03 0,01769553 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 3,77E-03 0,01765949 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 3,77E-03 0,01762359 ! protein prenylation GO:0018342 10 6 0,000 3,77E-03 0,01758784 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 3,77E-03 0,01755224 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 3,77E-03 0,01751678 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 3,77E-03 0,01748147 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 3,77E-03 0,01744629 ! positive regulation of coagulation GO:0050820 11 6 0,000 3,77E-03 0,01741126 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 4,397E-03 0,02026663 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 4,397E-03 0,0202261 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 4,397E-03 0,02018573 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 4,397E-03 0,02014552 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 4,397E-03 0,02010547 ! synaptonemal complex assembly GO:0007130 10 7 0,000 4,397E-03 0,02006557 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 4,397E-03 0,02002584 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 4,397E-03 0,01998626 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 4,397E-03 0,01994684 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 4,397E-03 0,01990758 ! reproductive behavior GO:0019098 12 7 0,000 4,397E-03 0,01986847 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 4,397E-03 0,01982951 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 4,397E-03 0,0197907 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 4,397E-03 0,01975205 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 4,397E-03 0,01971355 ! oligopeptide transport GO:0006857 11 7 0,000 4,397E-03 0,01967519 ! protein amino acid sulfation GO:0006477 9 7 0,000 4,397E-03 0,01963699 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 4,397E-03 0,01959893 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 4,397E-03 0,01956102 ! RNA methylation GO:0001510 11 7 0,000 4,397E-03 0,01952326 ! pericardium development GO:0060039 8 7 0,000 4,397E-03 0,01948564 ! macrophage chemotaxis GO:0048246 10 7 0,000 4,397E-03 0,01944817 ! fibril organization GO:0043206 13 7 0,000 4,397E-03 0,01941084 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 4,397E-03 0,01937366 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 4,397E-03 0,01933661 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 4,397E-03 0,01929971 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 4,397E-03 0,01926295 ! lipoprotein transport GO:0042953 9 7 0,000 4,397E-03 0,01922633 ! cerebral cortex cell migration GO:0021795 11 7 0,000 4,397E-03 0,01918985 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 4,397E-03 0,0191535 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 4,397E-03 0,0191173 ! estrogen metabolic process GO:0008210 14 7 0,000 4,397E-03 0,01908123 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 4,397E-03 0,01904529 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 4,397E-03 0,01900949 ! chemosensory behavior GO:0007635 9 7 0,000 4,397E-03 0,01897383 ! microtubule bundle formation GO:0001578 8 7 0,000 4,397E-03 0,01893829 ! T-helper 1 type immune response GO:0042088 11 7 0,000 4,397E-03 0,0189029 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 4,397E-03 0,01886763 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 4,397E-03 0,01883249 ! leukocyte degranulation GO:0043299 10 7 0,000 4,397E-03 0,01879749 ! bile acid and bile salt transport GO:0015721 9 7 0,000 4,397E-03 0,01876261 ! reflex GO:0060004 12 7 0,000 4,397E-03 0,01872787 ! positive regulation of isotype switching GO:0045830 15 7 0,000 4,397E-03 0,01869325 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 4,397E-03 0,01865876 ! protein-cofactor linkage GO:0018065 13 7 0,000 4,397E-03 0,0186244 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 4,397E-03 0,01859016 ! glycerolipid catabolic process GO:0046503 9 7 0,000 4,397E-03 0,01855605 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 4,397E-03 0,01852207 ! spinal cord patterning GO:0021511 7 7 0,000 4,397E-03 0,01848821 ! hemoglobin metabolic process GO:0020027 10 7 0,000 4,397E-03 0,01845447 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 4,397E-03 0,01842086 ! adrenal gland development GO:0030325 17 7 0,000 4,397E-03 0,01838736 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 4,397E-03 0,01835399 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 4,397E-03 0,01832074 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 4,397E-03 0,01828761 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 4,397E-03 0,0182546 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 4,397E-03 0,01822171 ! endosome organization GO:0007032 10 7 0,000 4,397E-03 0,01818894 ! thyroid hormone generation GO:0006590 11 7 0,000 4,397E-03 0,01815628 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 4,397E-03 0,01812374 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 4,397E-03 0,01809132 ! regulation of pigmentation during development GO:0048070 15 7 0,000 4,397E-03 0,01805902 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 4,397E-03 0,01802683 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 4,397E-03 0,01799475 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 4,397E-03 0,01796279 ! galactose metabolic process GO:0006012 10 7 0,000 4,397E-03 0,01793094 ! vesicle fusion GO:0006906 15 7 0,000 4,397E-03 0,0178992 ! intracellular pH reduction GO:0051452 10 7 0,000 4,397E-03 0,01786758 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 4,397E-03 0,01783607 ! organ growth GO:0035265 11 7 0,000 4,397E-03 0,01780466 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 4,397E-03 0,01777337 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 4,397E-03 0,01774219 ! Rac protein signal transduction GO:0016601 7 7 0,000 4,397E-03 0,01771112 ! retinol metabolic process GO:0042572 9 7 0,000 4,397E-03 0,01768016 ! behavioral fear response GO:0001662 13 7 0,000 4,397E-03 0,0176493 GO:0002209|behavioral defense response, ! negative regulation of muscle contraction GO:0045932 12 7 0,000 4,397E-03 0,01761855 ! rRNA modification GO:0000154 12 7 0,000 4,397E-03 0,01758791 ! protein heterooligomerization GO:0051291 10 7 0,000 4,397E-03 0,01755738 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 4,397E-03 0,01752695 ! response to UV-B GO:0010224 11 7 0,000 4,397E-03 0,01749663 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 4,397E-03 0,01746641 ! protein retention in ER lumen GO:0006621 12 7 0,000 4,397E-03 0,01743629 ! intermediate filament organization GO:0045109 11 7 0,000 4,397E-03 0,01740628 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 4,397E-03 0,01737637 ! cardiac muscle cell development GO:0055013 9 7 0,000 4,397E-03 0,01734657 ! fibrinolysis GO:0042730 9 7 0,000 4,397E-03 0,01731687 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 4,397E-03 0,01728726 ! regulation of circadian rhythm GO:0042752 11 7 0,000 4,397E-03 0,01725776 ! B cell lineage commitment GO:0002326 17 7 0,000 4,397E-03 0,01722836 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 4,397E-03 0,01719906 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 4,397E-03 0,01716986 ! response to tropane GO:0014073 13 7 0,000 4,397E-03 0,01714076 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 4,397E-03 0,01711176 ! melanosome localization GO:0032400 10 7 0,000 4,397E-03 0,01708285 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 4,397E-03 0,01705405 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 4,397E-03 0,01702534 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 4,397E-03 0,01699672 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 4,397E-03 0,0169682 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 4,397E-03 0,01693978 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 4,397E-03 0,01691145 ! mast cell activation GO:0045576 9 7 0,000 4,397E-03 0,01688322 ! multicellular organismal aging GO:0010259 11 7 0,000 4,397E-03 0,01685508 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 4,397E-03 0,01682704 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 4,397E-03 0,01679909 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 4,397E-03 0,01677123 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 4,397E-03 0,01674346 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 4,397E-03 0,01671578 ! establishment of nucleus localization GO:0040023 13 7 0,000 4,397E-03 0,0166882 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 4,397E-03 0,01666071 ! T cell lineage commitment GO:0002360 12 7 0,000 4,397E-03 0,01663331 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 4,397E-03 0,01660599 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 4,397E-03 0,01657877 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 4,397E-03 0,01655164 ! regulation of lipid transport GO:0032368 13 7 0,000 4,397E-03 0,01652459 ! response to tumor cell GO:0002347 12 7 0,000 4,397E-03 0,01649763 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 4,397E-03 0,01647076 ! neuroblast proliferation GO:0007405 13 7 0,000 4,397E-03 0,01644398 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 4,397E-03 0,01641729 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 4,397E-03 0,01639068 ! peptidyl-threonine modification GO:0018210 18 7 0,000 4,397E-03 0,01636416 ! diuresis GO:0030146 12 7 0,000 4,397E-03 0,01633772 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 4,397E-03 0,01631137 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 4,397E-03 0,0162851 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 4,397E-03 0,01625892 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 4,397E-03 0,01623282 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 4,397E-03 0,01620681 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 4,397E-03 0,01618088 ! melanin biosynthetic process GO:0042438 8 7 0,000 4,397E-03 0,01615503 ! regulation of synaptogenesis GO:0051963 10 7 0,000 4,397E-03 0,01612927 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 4,397E-03 0,01610358 ! dopamine biosynthetic process GO:0042416 15 7 0,000 4,397E-03 0,01607798 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 4,397E-03 0,01605246 ! lymph node development GO:0048535 9 7 0,000 4,397E-03 0,01602702 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 4,397E-03 0,01600166 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 4,397E-03 0,01597638 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 4,397E-03 0,01595118 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 4,397E-03 0,01592606 ! endosome to lysosome transport GO:0008333 10 7 0,000 4,397E-03 0,01590102 ! ATP catabolic process GO:0006200 10 7 0,000 4,397E-03 0,01587606 ! establishment of pigment granule localization GO:0051905 13 7 0,000 4,397E-03 0,01585117 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 4,397E-03 0,01582637 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 4,397E-03 0,01580164 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 4,397E-03 0,01577699 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 4,397E-03 0,01575241 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 4,397E-03 0,01572792 ! muscle adaptation GO:0043500 12 7 0,000 4,397E-03 0,01570349 ! amino sugar catabolic process GO:0046348 9 7 0,000 4,397E-03 0,01567915 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 4,397E-03 0,01565488 ! retina homeostasis GO:0001895 9 7 0,000 4,397E-03 0,01563068 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 4,397E-03 0,01560656 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 4,397E-03 0,01558251 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 4,397E-03 0,01555854 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 4,397E-03 0,01553464 ! behavioral response to nicotine GO:0035095 11 7 0,000 4,397E-03 0,01551081 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 4,397E-03 0,01548706 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 4,397E-03 0,01546338 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 5,024E-03 0,01764041 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 5,024E-03 0,01761352 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 11 8 0,000 5,024E-03 0,01758671 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 5,024E-03 0,01755998 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 5,024E-03 0,01753333 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 5,024E-03 0,01750677 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 5,024E-03 0,01748028 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 5,024E-03 0,01745388 ! cell proliferation in forebrain GO:0021846 10 8 0,000 5,024E-03 0,01742755 ! positive regulation of B cell proliferation GO:0030890 11 8 0,000 5,024E-03 0,0174013 ! phosphate transport GO:0006817 10 8 0,000 5,024E-03 0,01737514 ! N-glycan processing GO:0006491 12 8 0,000 5,024E-03 0,01734905 ! Golgi to endosome transport GO:0006895 16 8 0,000 5,024E-03 0,01732304 ! UTP metabolic process GO:0046051 8 8 0,000 5,024E-03 0,01729711 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 5,024E-03 0,01727125 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 5,024E-03 0,01724547 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 5,024E-03 0,01721977 ! neurotransmitter uptake GO:0001504 10 8 0,000 5,024E-03 0,01719415 ! succinate metabolic process GO:0006105 14 8 0,000 5,024E-03 0,0171686 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 5,024E-03 0,01714312 ! smoothened signaling pathway GO:0007224 8 8 0,000 5,024E-03 0,01711773 ! membrane hyperpolarization GO:0060081 10 8 0,000 5,024E-03 0,01709241 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 5,024E-03 0,01706716 ! keratinocyte proliferation GO:0043616 12 8 0,000 5,024E-03 0,01704199 ! middle ear morphogenesis GO:0042474 9 8 0,000 5,024E-03 0,01701689 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 5,024E-03 0,01699186 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 5,024E-03 0,01696691 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 5,024E-03 0,01694203 ! ganglioside metabolic process GO:0001573 15 8 0,000 5,024E-03 0,01691723 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 5,024E-03 0,01689249 ! pseudouridine synthesis GO:0001522 9 8 0,000 5,024E-03 0,01686783 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 5,024E-03 0,01684325 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 5,024E-03 0,01681873 ! endothelial cell differentiation GO:0045446 14 8 0,000 5,024E-03 0,01679428 ! ceramide biosynthetic process GO:0046513 9 8 0,000 5,024E-03 0,01676991 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 5,024E-03 0,0167456 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 0,000 5,024E-03 0,01672137 ! astrocyte differentiation GO:0048708 16 8 0,000 5,024E-03 0,01669721 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 5,024E-03 0,01667311 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 5,024E-03 0,01664909 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 5,024E-03 0,01662513 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 5,024E-03 0,01660124 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 5,024E-03 0,01657743 ! melanin metabolic process GO:0006582 12 8 0,000 5,024E-03 0,01655368 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 5,024E-03 0,01652999 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 5,024E-03 0,01650638 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 5,024E-03 0,01648283 ! macrophage activation GO:0042116 12 8 0,000 5,024E-03 0,01645935 ! regulation of type I interferon production GO:0032479 8 8 0,000 5,024E-03 0,01643594 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 5,024E-03 0,01641259 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 5,024E-03 0,01638931 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 5,024E-03 0,0163661 ! regulation of vascular permeability GO:0043114 12 8 0,000 5,024E-03 0,01634295 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 5,024E-03 0,01631987 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 5,024E-03 0,01629685 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 5,024E-03 0,0162739 ! ruffle organization GO:0031529 11 8 0,000 5,024E-03 0,01625101 ! osteoblast development GO:0002076 13 8 0,000 5,024E-03 0,01622818 ! lens development in camera-type eye GO:0002088 10 8 0,000 5,024E-03 0,01620542 ! positive regulation of vasodilation GO:0045909 12 8 0,000 5,024E-03 0,01618273 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 5,024E-03 0,01616009 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 5,024E-03 0,01613752 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 5,024E-03 0,01611502 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 5,024E-03 0,01609257 ! Schwann cell differentiation GO:0014037 17 8 0,000 5,024E-03 0,01607019 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 5,024E-03 0,01604787 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 5,024E-03 0,01602561 ! regulation of gliogenesis GO:0014013 20 8 0,000 5,024E-03 0,01600342 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 5,024E-03 0,01598128 ! oligodendrocyte development GO:0014003 8 8 0,000 5,024E-03 0,01595921 ! segment specification GO:0007379 10 8 0,000 5,024E-03 0,01593719 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 5,024E-03 0,01591524 ! cellular extravasation GO:0045123 11 8 0,000 5,024E-03 0,01589335 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 5,024E-03 0,01587152 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 5,024E-03 0,01584975 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 5,024E-03 0,01582804 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 5,024E-03 0,01580638 ! snRNA metabolic process GO:0016073 10 8 0,000 5,024E-03 0,01578479 GO:0016180|snRNA processing, ! phosphoinositide 3-kinase cascade GO:0014065 23 8 0,000 5,024E-03 0,01576326 ! regulation of interleukin-4 production GO:0032673 16 8 0,000 5,024E-03 0,01574178 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 5,024E-03 0,01572036 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 5,024E-03 0,015699 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 5,024E-03 0,0156777 ! nucleosome disassembly GO:0006337 12 8 0,000 5,024E-03 0,01565646 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 5,024E-03 0,01563527 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 5,024E-03 0,01561414 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 5,024E-03 0,01559307 ! icosanoid secretion GO:0032309 12 8 0,000 5,024E-03 0,01557206 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 5,024E-03 0,0155511 ! leukocyte activation during immune response GO:0002366 13 8 0,000 5,024E-03 0,0155302 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 5,024E-03 0,01550935 ! cerebellum morphogenesis GO:0021587 9 8 0,000 5,024E-03 0,01548856 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 5,024E-03 0,01546783 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 5,024E-03 0,01544715 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 5,024E-03 0,01542652 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 5,024E-03 0,01540595 ! sterol catabolic process GO:0016127 9 8 0,000 5,024E-03 0,01538544 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 5,024E-03 0,01536498 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 5,024E-03 0,01534458 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 5,024E-03 0,01532423 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 5,024E-03 0,01530393 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 5,024E-03 0,01528369 ! prophase GO:0051324 11 8 0,000 5,024E-03 0,0152635 ! S phase GO:0051320 8 8 0,000 5,024E-03 0,01524336 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 5,024E-03 0,01522328 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 5,024E-03 0,01520324 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 5,024E-03 0,01518327 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 5,024E-03 0,01516334 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 5,024E-03 0,01514347 ! hormone catabolic process GO:0042447 13 8 0,000 5,024E-03 0,01512365 ! quaternary ammonium group transport GO:0015697 10 8 0,000 5,024E-03 0,01510388 ! myeloid cell homeostasis GO:0002262 8 8 0,000 5,024E-03 0,01508416 ! regulation of fibrinolysis GO:0051917 13 8 0,000 5,024E-03 0,01506449 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 5,024E-03 0,01504488 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 5,024E-03 0,01502531 ! regulation of telomere maintenance GO:0032204 10 8 0,000 5,024E-03 0,0150058 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 5,024E-03 0,01498634 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 5,024E-03 0,01496693 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 5,024E-03 0,01494756 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 5,024E-03 0,01492825 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 5,024E-03 0,01490899 ! lamellipodium assembly GO:0030032 9 8 0,000 5,024E-03 0,01488978 ! regulation of embryonic development GO:0045995 16 8 0,000 5,024E-03 0,01487061 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 5,024E-03 0,0148515 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 5,024E-03 0,01483243 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 5,024E-03 0,01481342 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 5,65E-03 0,016639 ! regulation of developmental growth GO:0048638 13 9 0,000 5,65E-03 0,01661772 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 5,65E-03 0,0165965 ! telencephalon cell migration GO:0022029 16 9 0,000 5,65E-03 0,01657533 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 5,65E-03 0,01655421 ! pentose-phosphate shunt GO:0006098 12 9 0,000 5,65E-03 0,01653315 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 5,65E-03 0,01651214 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 5,65E-03 0,01649119 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 5,65E-03 0,01647029 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 5,65E-03 0,01644944 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 5,65E-03 0,01642864 ! GTP metabolic process GO:0046039 9 9 0,000 5,65E-03 0,0164079 ! elastic fiber assembly GO:0048251 13 9 0,000 5,65E-03 0,01638721 ! social behavior GO:0035176 14 9 0,000 5,65E-03 0,01636657 ! artery development GO:0060840 19 9 0,000 5,65E-03 0,01634598 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 5,65E-03 0,01632545 ! regulation of glycolysis GO:0006110 15 9 0,000 5,65E-03 0,01630497 ! response to pain GO:0048265 16 9 0,000 5,65E-03 0,01628453 ! protein complex disassembly GO:0043241 17 9 0,000 5,65E-03 0,01626415 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 5,65E-03 0,01624382 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 5,65E-03 0,01622354 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 5,65E-03 0,01620331 ! lung alveolus development GO:0048286 17 9 0,000 5,65E-03 0,01618314 ! ciliary or flagellar motility GO:0001539 10 9 0,000 5,65E-03 0,01616301 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 5,65E-03 0,01614293 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 5,65E-03 0,0161229 ! ventral spinal cord development GO:0021517 11 9 0,000 5,65E-03 0,01610292 ! protein targeting to ER GO:0045047 19 9 0,000 5,65E-03 0,01608299 ! T cell selection GO:0045058 18 9 0,000 5,65E-03 0,01606311 ! endoderm development GO:0007492 12 9 0,000 5,65E-03 0,01604328 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 5,65E-03 0,0160235 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 5,65E-03 0,01600377 ! arginine catabolic process GO:0006527 10 9 0,000 5,65E-03 0,01598408 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 5,65E-03 0,01596444 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 5,65E-03 0,01594486 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 5,65E-03 0,01592532 ! phosphagen metabolic process GO:0006599 12 9 0,000 5,65E-03 0,01590582 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 5,65E-03 0,01588638 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 5,65E-03 0,01586698 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 5,65E-03 0,01584763 ! regulation of stress fiber formation GO:0051492 20 9 0,000 5,65E-03 0,01582833 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 5,65E-03 0,01580907 ! mannose metabolic process GO:0006013 9 9 0,000 5,65E-03 0,01578986 ! substrate-bound cell migration GO:0006929 10 9 0,000 5,65E-03 0,0157707 ! receptor clustering GO:0043113 15 9 0,000 5,65E-03 0,01575159 ! epithelial cell development GO:0002064 10 9 0,000 5,65E-03 0,01573252 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 5,65E-03 0,01571349 ! retinoic acid metabolic process GO:0042573 11 9 0,000 5,65E-03 0,01569451 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 5,65E-03 0,01567558 ! positive regulation of translational initiation GO:0045948 10 9 0,000 5,65E-03 0,0156567 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 5,65E-03 0,01563786 ! motor axon guidance GO:0008045 14 9 0,000 5,65E-03 0,01561906 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 5,65E-03 0,01560031 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 5,65E-03 0,0155816 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 5,65E-03 0,01556294 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 5,65E-03 0,01554433 ! blastoderm segmentation GO:0007350 11 9 0,000 5,65E-03 0,01552576 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 5,65E-03 0,01550723 ! DNA ligation GO:0006266 14 9 0,000 5,65E-03 0,01548875 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 5,65E-03 0,01547031 ! response to amine stimulus GO:0014075 13 9 0,000 5,65E-03 0,01545191 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 5,65E-03 0,01543356 ! erythrocyte development GO:0048821 11 9 0,000 5,65E-03 0,01541525 ! renal water homeostasis GO:0003091 14 9 0,000 5,65E-03 0,01539699 ! postreplication repair GO:0006301 11 9 0,000 5,65E-03 0,01537877 ! mRNA cleavage GO:0006379 13 9 0,000 5,65E-03 0,01536059 ! hindbrain morphogenesis GO:0021575 12 9 0,000 5,65E-03 0,01534245 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 5,65E-03 0,01532436 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 5,65E-03 0,01530631 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 5,65E-03 0,0152883 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 5,65E-03 0,01527034 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 5,65E-03 0,01525242 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 5,65E-03 0,01523453 ! acid secretion GO:0046717 14 9 0,000 5,65E-03 0,0152167 ! musculoskeletal movement GO:0050881 11 9 0,000 5,65E-03 0,0151989 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 5,65E-03 0,01518114 ! methionine biosynthetic process GO:0009086 10 9 0,000 5,65E-03 0,01516343 ! purine base metabolic process GO:0006144 18 9 0,000 5,65E-03 0,01514576 ! oocyte differentiation GO:0009994 12 9 0,000 5,65E-03 0,01512812 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 5,65E-03 0,01511053 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 5,65E-03 0,01509298 ! spleen development GO:0048536 15 9 0,000 5,65E-03 0,01507547 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 5,65E-03 0,015058 ! anterior/posterior axis specification GO:0009948 11 9 0,000 5,65E-03 0,01504058 ! regulation of RNA splicing GO:0043484 14 9 0,000 5,65E-03 0,01502319 ! detection of calcium ion GO:0005513 13 9 0,000 5,65E-03 0,01500584 ! blastocyst formation GO:0001825 12 9 0,000 5,65E-03 0,01498853 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 5,65E-03 0,01497126 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 5,65E-03 0,01495404 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 5,65E-03 0,01493685 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 5,65E-03 0,0149197 ! regulation of amino acid transport GO:0051955 11 9 0,000 5,65E-03 0,01490259 ! positive regulation of amine transport GO:0051954 15 9 0,000 5,65E-03 0,01488552 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 5,65E-03 0,01486849 ! prepulse inhibition GO:0060134 14 9 0,000 5,65E-03 0,01485149 ! embryonic placenta development GO:0001892 12 9 0,000 5,65E-03 0,01483454 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 5,65E-03 0,01481763 ! insulin secretion GO:0030073 17 9 0,000 5,65E-03 0,01480075 ! sequestering of metal ion GO:0051238 11 9 0,000 5,65E-03 0,01478391 ! response to nicotine GO:0035094 16 9 0,000 5,65E-03 0,01476711 ! establishment of cell polarity GO:0030010 12 9 0,000 5,65E-03 0,01475035 ! nucleus localization GO:0051647 15 9 0,000 5,65E-03 0,01473363 ! regulation of synapse organization GO:0050807 12 9 0,000 5,65E-03 0,01471694 ! localization within membrane GO:0051668 15 9 0,000 5,65E-03 0,01470029 ! negative regulation of muscle development GO:0048635 12 10 0,000 6,276E-03 0,01631054 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 6,276E-03 0,01629213 ! neuron fate specification GO:0048665 11 10 0,000 6,276E-03 0,01627376 ! negative regulation of blood pressure GO:0045776 22 10 0,000 6,276E-03 0,01625543 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 6,276E-03 0,01623715 ! thyroid gland development GO:0030878 19 10 0,000 6,276E-03 0,0162189 ! regulation of phosphatase activity GO:0010921 21 10 0,000 6,276E-03 0,0162007 ! synapsis GO:0007129 13 10 0,000 6,276E-03 0,01618254 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 6,276E-03 0,01616442 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 6,276E-03 0,01614634 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 6,276E-03 0,0161283 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 6,276E-03 0,0161103 ! sulfate transport GO:0008272 12 10 0,000 6,276E-03 0,01609234 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 6,276E-03 0,01607442 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 6,276E-03 0,01605654 ! androgen metabolic process GO:0008209 13 10 0,000 6,276E-03 0,01603869 ! phospholipid efflux GO:0033700 16 10 0,000 6,276E-03 0,01602089 ! hippocampus development GO:0021766 19 10 0,000 6,276E-03 0,01600313 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 6,276E-03 0,01598541 ! blood vessel remodeling GO:0001974 21 10 0,000 6,276E-03 0,01596773 ! positive regulation of heart contraction GO:0045823 14 10 0,000 6,276E-03 0,01595008 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 6,276E-03 0,01593248 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 6,276E-03 0,01591491 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 6,276E-03 0,01589738 ! pathogenesis GO:0009405 13 10 0,000 6,276E-03 0,0158799 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 6,276E-03 0,01586245 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 6,276E-03 0,01584503 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 6,276E-03 0,01582766 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 6,276E-03 0,01581032 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 6,276E-03 0,01579303 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 6,276E-03 0,01577577 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 6,276E-03 0,01575854 ! melanocyte differentiation GO:0030318 15 10 0,000 6,276E-03 0,01574136 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 6,276E-03 0,01572421 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 6,276E-03 0,0157071 ! reverse cholesterol transport GO:0043691 16 10 0,000 6,276E-03 0,01569003 ! response to X-ray GO:0010165 16 10 0,000 6,276E-03 0,01567299 ! B cell proliferation GO:0042100 14 10 0,000 6,276E-03 0,01565599 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 6,276E-03 0,01563903 ! regulation of sodium ion transport GO:0002028 15 10 0,000 6,276E-03 0,01562211 ! forebrain cell migration GO:0021885 17 10 0,000 6,276E-03 0,01560522 ! lipid digestion GO:0044241 15 10 0,000 6,276E-03 0,01558836 ! phagocytosis, engulfment GO:0006911 20 10 0,000 6,276E-03 0,01557155 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 6,276E-03 0,01555477 ! UV protection GO:0009650 14 10 0,000 6,276E-03 0,01553803 ! entry into host cell GO:0030260 20 10 0,000 6,276E-03 0,01552132 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 6,276E-03 0,01550465 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 6,276E-03 0,01548801 ! negative regulation of ossification GO:0030279 19 10 0,000 6,276E-03 0,01547141 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 6,276E-03 0,01545485 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 6,276E-03 0,01543832 ! regulation of bone resorption GO:0045124 24 10 0,000 6,276E-03 0,01542182 ! alpha-beta T cell activation GO:0046631 16 10 0,000 6,276E-03 0,01540536 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 6,276E-03 0,01538894 ! regulation of organ growth GO:0046620 11 10 0,000 6,276E-03 0,01537255 ! response to dsRNA GO:0043331 18 10 0,000 6,276E-03 0,0153562 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 6,276E-03 0,01533988 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 6,276E-03 0,01532359 ! embryonic axis specification GO:0000578 12 10 0,000 6,276E-03 0,01530734 ! regulation of B cell differentiation GO:0045577 16 10 0,000 6,276E-03 0,01529113 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 6,276E-03 0,01527495 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 6,276E-03 0,0152588 ! cranial nerve development GO:0021545 12 10 0,000 6,276E-03 0,01524269 ! fucose catabolic process GO:0019317 16 10 0,000 6,276E-03 0,01522661 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 6,276E-03 0,01521056 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 6,276E-03 0,01519455 ! protein sumoylation GO:0016925 12 10 0,000 6,276E-03 0,01517858 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 6,276E-03 0,01516263 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 6,276E-03 0,01514672 ! zymogen activation GO:0031638 14 10 0,000 6,276E-03 0,01513084 ! salivary gland development GO:0007431 22 10 0,000 6,276E-03 0,015115 ! negative regulation of neurological system process GO:0031645 19 10 0,000 6,276E-03 0,01509919 ! glutathione biosynthetic process GO:0006750 11 10 0,000 6,276E-03 0,01508341 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 6,276E-03 0,01506767 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 6,276E-03 0,01505196 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 6,276E-03 0,01503628 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 6,276E-03 0,01502063 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 6,276E-03 0,01500502 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 6,276E-03 0,01498943 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 6,276E-03 0,01497389 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 6,276E-03 0,01495837 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 6,276E-03 0,01494288 ! detection of bacterium GO:0016045 10 10 0,000 6,276E-03 0,01492743 ! embryonic gut development GO:0048566 11 10 0,000 6,276E-03 0,01491201 ! activation of innate immune response GO:0002218 10 10 0,000 6,276E-03 0,01489662 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 6,276E-03 0,01488126 ! cardiac cell differentiation GO:0035051 16 10 0,000 6,276E-03 0,01486594 ! developmental induction GO:0031128 13 10 0,000 6,276E-03 0,01485064 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 6,276E-03 0,01483538 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 6,276E-03 0,01482015 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 6,276E-03 0,01480495 ! negative regulation of immune effector process GO:0002698 16 10 0,000 6,276E-03 0,01478978 ! rRNA transcription GO:0009303 17 11 0,000 6,902E-03 0,01624746 ! respiratory burst GO:0045730 14 11 0,000 6,902E-03 0,01623085 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 6,902E-03 0,01621427 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 6,902E-03 0,01619772 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 6,902E-03 0,01618121 ! virus-host interaction GO:0019048 17 11 0,000 6,902E-03 0,01616473 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 6,902E-03 0,01614829 ! filopodium assembly GO:0046847 19 11 0,000 6,902E-03 0,01613188 ! Golgi vesicle budding GO:0048194 17 11 0,000 6,902E-03 0,0161155 ! RNA polyadenylation GO:0043631 19 11 0,000 6,902E-03 0,01609916 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 6,902E-03 0,01608285 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 6,902E-03 0,01606657 ! mating GO:0007618 14 11 0,000 6,902E-03 0,01605032 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 6,902E-03 0,01603411 ! T cell proliferation GO:0042098 20 11 0,000 6,902E-03 0,01601793 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 6,902E-03 0,01600178 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 6,902E-03 0,01598567 ! bone resorption GO:0045453 16 11 0,000 6,902E-03 0,01596959 ! regulated secretory pathway GO:0045055 14 11 0,000 6,902E-03 0,01595354 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 6,902E-03 0,01593752 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 6,902E-03 0,01592153 ! regulation of mRNA processing GO:0050684 18 11 0,000 6,902E-03 0,01590558 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 6,902E-03 0,01588966 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 6,902E-03 0,01587377 ! syncytium formation GO:0006949 15 11 0,000 6,902E-03 0,01585791 ! plasma membrane organization GO:0007009 18 11 0,000 6,902E-03 0,01584208 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 6,902E-03 0,01582629 ! focal adhesion formation GO:0048041 24 11 0,000 6,902E-03 0,01581053 ! mitotic spindle organization GO:0007052 15 11 0,000 6,902E-03 0,01579479 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 6,902E-03 0,01577909 ! regulation of intracellular pH GO:0051453 17 11 0,000 6,902E-03 0,01576342 ! membrane protein proteolysis GO:0033619 18 11 0,000 6,902E-03 0,01574779 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 6,902E-03 0,01573218 ! adult heart development GO:0007512 11 11 0,000 6,902E-03 0,0157166 ! chondrocyte differentiation GO:0002062 17 11 0,000 6,902E-03 0,01570106 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 6,902E-03 0,01568554 ! temperature homeostasis GO:0001659 16 11 0,000 6,902E-03 0,01567006 ! L-glutamate transport GO:0015813 16 11 0,000 6,902E-03 0,0156546 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 6,902E-03 0,01563918 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 6,902E-03 0,01562379 ! protein targeting to peroxisome GO:0006625 20 11 0,000 6,902E-03 0,01560843 ! stem cell development GO:0048864 29 11 0,000 6,902E-03 0,01559309 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 6,902E-03 0,01557779 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 6,902E-03 0,01556252 ! regulation of phagocytosis GO:0050764 14 11 0,000 6,902E-03 0,01554728 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 6,902E-03 0,01553206 ! vasoconstriction GO:0042310 15 11 0,000 6,902E-03 0,01551688 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 6,902E-03 0,01550173 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 6,902E-03 0,0154866 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 6,902E-03 0,01547151 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 6,902E-03 0,01545644 ! ribosome assembly GO:0042255 13 11 0,000 6,902E-03 0,01544141 ! nitric oxide metabolic process GO:0046209 14 11 0,000 6,902E-03 0,0154264 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 6,902E-03 0,01541143 ! chromatin silencing GO:0006342 19 11 0,000 6,902E-03 0,01539648 ! nucleosome positioning GO:0016584 13 11 0,000 6,902E-03 0,01538156 ! regulation of isotype switching GO:0045191 19 11 0,000 6,902E-03 0,01536667 ! regulation of leukocyte migration GO:0002685 24 11 0,000 6,902E-03 0,01535181 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 6,902E-03 0,01533697 ! protein-chromophore linkage GO:0018298 13 11 0,000 6,902E-03 0,01532217 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 6,902E-03 0,01530739 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 6,902E-03 0,01529265 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 6,902E-03 0,01527793 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 6,902E-03 0,01526324 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 6,902E-03 0,01524858 ! male genitalia development GO:0030539 13 11 0,000 6,902E-03 0,01523394 ! cholesterol efflux GO:0033344 19 11 0,000 6,902E-03 0,01521934 ! digestive tract morphogenesis GO:0048546 15 11 0,000 6,902E-03 0,01520476 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 6,902E-03 0,01519021 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 6,902E-03 0,01517569 ! negative regulation of glucose import GO:0046325 14 11 0,000 6,902E-03 0,01516119 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 6,902E-03 0,01514673 ! regulation of organic acid transport GO:0032890 17 11 0,000 6,902E-03 0,01513229 ! defense response to fungus GO:0050832 12 11 0,000 6,902E-03 0,01511787 ! mRNA 3'-end processing GO:0031124 19 11 0,000 6,902E-03 0,01510349 ! lysogeny GO:0030069 18 11 0,000 6,902E-03 0,01508913 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 6,902E-03 0,0150748 ! acrosome reaction GO:0007340 13 11 0,000 6,902E-03 0,0150605 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 6,902E-03 0,01504623 ! lactation GO:0007595 20 12 0,000 7,527E-03 0,01639383 ! reproductive cellular process GO:0048610 14 12 0,000 7,527E-03 0,01637832 ! tRNA modification GO:0006400 14 12 0,000 7,527E-03 0,01636284 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 7,527E-03 0,01634739 ! positive regulation of blood pressure GO:0045777 16 12 0,000 7,527E-03 0,01633197 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 7,527E-03 0,01631658 ! 'de novo' protein folding GO:0006458 18 12 0,000 7,527E-03 0,01630121 ! dicarboxylic acid transport GO:0006835 22 12 0,000 7,527E-03 0,01628588 ! non-recombinational repair GO:0000726 19 12 0,000 7,527E-03 0,01627057 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 7,527E-03 0,01625529 ! peroxisomal transport GO:0043574 21 12 0,000 7,527E-03 0,01624005 ! cartilage condensation GO:0001502 18 12 0,000 7,527E-03 0,01622482 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 7,527E-03 0,01620963 ! cytokine biosynthetic process GO:0042089 16 12 0,000 7,527E-03 0,01619447 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 7,527E-03 0,01617933 ! heart looping GO:0001947 15 12 0,000 7,527E-03 0,01616423 ! palate development GO:0060021 15 12 0,000 7,527E-03 0,01614915 ! positive regulation of cell growth GO:0030307 16 12 0,000 7,527E-03 0,0161341 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 7,527E-03 0,01611908 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 7,527E-03 0,01610408 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 7,527E-03 0,01608912 ! arginine metabolic process GO:0006525 13 12 0,000 7,527E-03 0,01607418 ! glycoprotein catabolic process GO:0006516 19 12 0,000 7,527E-03 0,01605927 ! methionine metabolic process GO:0006555 13 12 0,000 7,527E-03 0,01604438 ! tyrosine metabolic process GO:0006570 14 12 0,000 7,527E-03 0,01602953 ! Golgi organization GO:0007030 18 12 0,000 7,527E-03 0,0160147 ! cell-cell junction assembly GO:0007043 18 12 0,000 7,527E-03 0,0159999 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 7,527E-03 0,01598512 ! monoamine transport GO:0015844 13 12 0,000 7,527E-03 0,01597038 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 7,527E-03 0,01595566 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 7,527E-03 0,01594097 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 7,527E-03 0,0159263 ! L-amino acid transport GO:0015807 20 12 0,000 7,527E-03 0,01591166 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 7,527E-03 0,01589705 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 7,527E-03 0,01588247 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 7,527E-03 0,01586791 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 7,527E-03 0,01585338 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 7,527E-03 0,01583887 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 7,527E-03 0,0158244 ! cerebellum development GO:0021549 13 12 0,000 7,527E-03 0,01580994 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 7,527E-03 0,01579552 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 7,527E-03 0,01578112 ! histone acetylation GO:0016573 23 12 0,000 7,527E-03 0,01576675 ! histone methylation GO:0016571 15 12 0,000 7,527E-03 0,0157524 ! autonomic nervous system development GO:0048483 23 12 0,000 7,527E-03 0,01573808 ! gland morphogenesis GO:0022612 23 12 0,000 7,527E-03 0,01572379 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 7,527E-03 0,01570952 ! peptidyl-lysine modification GO:0018205 18 12 0,000 7,527E-03 0,01569527 ! negative regulation of protein secretion GO:0050709 20 12 0,000 7,527E-03 0,01568106 ! response to gamma radiation GO:0010332 20 12 0,000 7,527E-03 0,01566687 ! regulation of epidermis development GO:0045682 17 12 0,000 7,527E-03 0,0156527 ! intestinal absorption GO:0050892 19 12 0,000 7,527E-03 0,01563856 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 7,527E-03 0,01562445 ! cAMP biosynthetic process GO:0006171 20 12 0,000 7,527E-03 0,01561036 ! regulation of mRNA stability GO:0043488 27 12 0,000 7,527E-03 0,0155963 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 7,527E-03 0,01558226 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 7,527E-03 0,01556824 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 7,527E-03 0,01555426 ! RNA 3'-end processing GO:0031123 20 12 0,000 7,527E-03 0,01554029 ! microspike assembly GO:0030035 23 12 0,000 7,527E-03 0,01552636 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 7,527E-03 0,01551244 ! response to cold GO:0009409 14 12 0,000 7,527E-03 0,01549856 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 8,152E-03 0,01677029 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 8,152E-03 0,0167553 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 8,152E-03 0,01674034 ! cGMP metabolic process GO:0046068 16 13 0,000 8,152E-03 0,01672541 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 8,152E-03 0,0167105 ! water transport GO:0006833 17 13 0,000 8,152E-03 0,01669562 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 8,152E-03 0,01668077 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 8,152E-03 0,01666594 ! lipid localization GO:0010876 24 13 0,000 8,152E-03 0,01665114 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 8,152E-03 0,01663637 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 8,152E-03 0,01662162 ! organelle fusion GO:0048284 28 13 0,000 8,152E-03 0,0166069 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 8,152E-03 0,0165922 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 8,152E-03 0,01657753 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 8,152E-03 0,01656288 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 8,152E-03 0,01654827 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 8,152E-03 0,01653367 ! response to hexose stimulus GO:0009746 19 13 0,000 8,152E-03 0,01651911 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! glutamate metabolic process GO:0006536 18 13 0,000 8,152E-03 0,01650456 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 8,152E-03 0,01649005 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 8,152E-03 0,01647556 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 8,152E-03 0,01646109 ! NAD metabolic process GO:0019674 21 13 0,000 8,152E-03 0,01644665 ! exocrine system development GO:0035272 27 13 0,000 8,152E-03 0,01643224 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 8,152E-03 0,01641785 ! bone mineralization GO:0030282 15 13 0,000 8,152E-03 0,01640349 ! regulation of exocytosis GO:0017157 17 13 0,000 8,152E-03 0,01638915 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 8,152E-03 0,01637483 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 8,152E-03 0,01636055 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 8,152E-03 0,01634628 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 8,152E-03 0,01633204 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 8,152E-03 0,01631783 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 8,152E-03 0,01630364 ! genitalia development GO:0048806 15 13 0,000 8,152E-03 0,01628947 ! regulation of cellular pH GO:0030641 20 13 0,000 8,152E-03 0,01627533 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 8,152E-03 0,01626122 ! cellular pigmentation GO:0033059 24 13 0,000 8,152E-03 0,01624713 ! tissue regeneration GO:0042246 21 13 0,000 8,152E-03 0,01623306 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 8,152E-03 0,01621902 ! cofactor transport GO:0051181 19 13 0,000 8,152E-03 0,016205 ! NADP metabolic process GO:0006739 18 13 0,000 8,152E-03 0,01619101 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 8,152E-03 0,01617704 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 8,152E-03 0,01616309 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 8,152E-03 0,01614917 ! gas transport GO:0015669 18 13 0,000 8,152E-03 0,01613527 ! regulation of RNA stability GO:0043487 28 13 0,000 8,152E-03 0,0161214 ! heme biosynthetic process GO:0006783 20 13 0,000 8,152E-03 0,01610755 ! regulation of axon extension GO:0030516 23 13 0,000 8,152E-03 0,01609372 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 8,152E-03 0,01607992 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 8,152E-03 0,01606614 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 8,152E-03 0,01605238 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 8,152E-03 0,01603865 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 8,152E-03 0,01602494 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 8,776E-03 0,01723797 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 8,776E-03 0,01722326 ! superoxide anion generation GO:0042554 18 14 0,000 8,776E-03 0,01720857 ! neuron maturation GO:0042551 21 14 0,000 8,776E-03 0,01719392 ! regulation of S phase GO:0033261 18 14 0,000 8,776E-03 0,01717928 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 8,776E-03 0,01716468 ! myotube differentiation GO:0014902 21 14 0,000 8,776E-03 0,01715009 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 8,776E-03 0,01713553 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 8,776E-03 0,017121 ! heterophilic cell adhesion GO:0007157 29 14 0,000 8,776E-03 0,01710649 ! inositol metabolic process GO:0006020 20 14 0,000 8,776E-03 0,01709201 ! aminoglycan catabolic process GO:0006026 18 14 0,000 8,776E-03 0,01707755 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 8,776E-03 0,01706311 ! retina development in camera-type eye GO:0060041 18 14 0,000 8,776E-03 0,0170487 ! cardiac muscle contraction GO:0060048 23 14 0,000 8,776E-03 0,01703431 ! gene silencing by RNA GO:0031047 20 14 0,000 8,776E-03 0,01701995 ! response to cAMP GO:0051591 19 14 0,000 8,776E-03 0,01700561 ! limbic system development GO:0021761 25 14 0,000 8,776E-03 0,01699129 ! startle response GO:0001964 21 14 0,000 8,776E-03 0,016977 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 8,776E-03 0,01696274 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 8,776E-03 0,0169485 ! activation of MAPKK activity GO:0000186 21 14 0,000 8,776E-03 0,01693428 ! regulation of defense response to virus GO:0050688 24 14 0,000 8,776E-03 0,01692008 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 8,776E-03 0,01690591 ! epidermis morphogenesis GO:0048730 29 14 0,000 8,776E-03 0,01689176 ! glycine metabolic process GO:0006544 22 14 0,000 8,776E-03 0,01687764 ! pituitary gland development GO:0021983 23 14 0,000 8,776E-03 0,01686354 ! cellular response to starvation GO:0009267 21 14 0,000 8,776E-03 0,01684946 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 8,776E-03 0,01683541 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 8,776E-03 0,01682138 ! regulation of heart rate GO:0002027 23 14 0,000 8,776E-03 0,01680738 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 8,776E-03 0,01679339 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 8,776E-03 0,01677943 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 8,776E-03 0,0167655 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 8,776E-03 0,01675158 ! G1/S transition checkpoint GO:0031575 33 14 0,000 8,776E-03 0,01673769 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 8,776E-03 0,01672383 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 8,776E-03 0,01670998 ! axon cargo transport GO:0008088 27 14 0,000 8,776E-03 0,01669616 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 8,776E-03 0,01668236 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 8,776E-03 0,01666859 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 8,776E-03 0,01665483 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 8,776E-03 0,0166411 ! mRNA splice site selection GO:0006376 26 14 0,000 8,776E-03 0,0166274 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 8,776E-03 0,01661371 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 8,776E-03 0,01660005 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 8,776E-03 0,01658641 ! sphingolipid catabolic process GO:0030149 23 14 0,000 8,776E-03 0,01657279 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 8,776E-03 0,01655919 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 8,776E-03 0,01654562 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 8,776E-03 0,01653207 ! muscle maintenance GO:0046716 19 14 0,000 8,776E-03 0,01651854 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 8,776E-03 0,01650504 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 8,776E-03 0,01649155 ! regulation of ATPase activity GO:0043462 18 14 0,000 8,776E-03 0,01647809 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 8,776E-03 0,01646465 ! cell killing GO:0001906 20 14 0,000 8,776E-03 0,01645123 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 8,776E-03 0,01643783 ! cilium assembly GO:0042384 20 14 0,000 8,776E-03 0,01642446 ! peptide hormone secretion GO:0030072 23 14 0,000 8,776E-03 0,0164111 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 9,401E-03 0,01756402 ! positive regulation of cell size GO:0045793 20 15 0,000 9,401E-03 0,01754976 ! metencephalon development GO:0022037 19 15 0,000 9,401E-03 0,01753553 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 9,401E-03 0,01752132 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 9,401E-03 0,01750713 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 9,401E-03 0,01749297 ! skin development GO:0043588 25 15 0,000 9,401E-03 0,01747883 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 9,401E-03 0,01746471 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 9,401E-03 0,01745061 ! lipid phosphorylation GO:0046834 23 15 0,000 9,401E-03 0,01743654 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 9,401E-03 0,01742249 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 9,401E-03 0,01740846 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 9,401E-03 0,01739446 ! bile acid metabolic process GO:0008206 22 15 0,000 9,401E-03 0,01738047 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 9,401E-03 0,01736651 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 9,401E-03 0,01735258 ! adult walking behavior GO:0007628 25 15 0,000 9,401E-03 0,01733866 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 9,401E-03 0,01732477 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 9,401E-03 0,0173109 ! myoblast differentiation GO:0045445 27 15 0,000 9,401E-03 0,01729705 ! centrosome cycle GO:0007098 16 15 0,000 9,401E-03 0,01728322 ! positive regulation of proteolysis GO:0045862 19 15 0,000 9,401E-03 0,01726942 ! regulation of survival gene product expression GO:0045884 20 15 0,000 9,401E-03 0,01725563 ! cardiac muscle tissue development GO:0048738 23 15 0,000 9,401E-03 0,01724187 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 9,401E-03 0,01722814 ! cerebral cortex development GO:0021987 29 15 0,000 9,401E-03 0,01721442 ! response to osmotic stress GO:0006970 22 15 0,000 9,401E-03 0,01720072 ! vesicle coating GO:0006901 25 15 0,000 9,401E-03 0,01718705 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 9,401E-03 0,0171734 ! DNA integration GO:0015074 22 15 0,000 9,401E-03 0,01715977 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 9,401E-03 0,01714616 ! peptide secretion GO:0002790 27 15 0,000 9,401E-03 0,01713258 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 9,401E-03 0,01711901 ! regulation of vasodilation GO:0042312 24 15 0,000 9,401E-03 0,01710547 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 9,401E-03 0,01709194 ! neuron recognition GO:0008038 22 15 0,000 9,401E-03 0,01707844 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 9,401E-03 0,01706496 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 9,401E-03 0,01705151 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 9,401E-03 0,01703807 ! peptide biosynthetic process GO:0043043 19 15 0,000 9,401E-03 0,01702465 ! biomineral formation GO:0031214 18 15 0,000 9,401E-03 0,01701126 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 9,401E-03 0,01699788 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 9,401E-03 0,01698453 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 9,401E-03 0,0169712 ! dopamine metabolic process GO:0042417 30 15 0,000 9,401E-03 0,01695789 ! organic cation transport GO:0015695 19 15 0,000 9,401E-03 0,0169446 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 9,401E-03 0,01693133 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 9,401E-03 0,01691808 ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 9,401E-03 0,01690486 ! defense response to virus GO:0051607 27 15 0,000 9,401E-03 0,01689165 ! peptide hormone processing GO:0016486 19 15 0,000 9,401E-03 0,01687846 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 9,401E-03 0,0168653 ! protein secretion GO:0009306 27 16 0,000 0,01002441 0,01797049 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,01002441 0,01795649 ! hormone secretion GO:0046879 25 16 0,000 0,01002441 0,01794252 ! bone remodeling GO:0046849 24 16 0,000 0,01002441 0,01792857 ! endothelial cell migration GO:0043542 22 16 0,000 0,01002441 0,01791464 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,01002441 0,01790073 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,01002441 0,01788684 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,01002441 0,01787298 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,01002441 0,01785913 ! glial cell development GO:0021782 24 16 0,000 0,01002441 0,01784531 ! patterning of blood vessels GO:0001569 24 16 0,000 0,01002441 0,01783151 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,01002441 0,01781773 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,01002441 0,01780397 ! protein polyubiquitination GO:0000209 26 16 0,000 0,01002441 0,01779023 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,01002441 0,01777651 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,01002441 0,01776282 ! fructose metabolic process GO:0006000 20 16 0,000 0,01002441 0,01774914 ! regulation of protein binding GO:0043393 27 16 0,000 0,01002441 0,01773549 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,01002441 0,01772186 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,01002441 0,01770825 ! protein export from nucleus GO:0006611 24 16 0,000 0,01002441 0,01769466 ! negative regulation of immune response GO:0050777 28 16 0,000 0,01002441 0,01768109 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,01002441 0,01766754 ! DNA replication initiation GO:0006270 25 16 0,000 0,01002441 0,01765401 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,01002441 0,0176405 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,01002441 0,01762702 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,01002441 0,01761355 ! diencephalon development GO:0021536 25 16 0,000 0,01002441 0,01760011 ! oogenesis GO:0048477 23 16 0,000 0,01002441 0,01758668 ! neural crest cell migration GO:0001755 24 16 0,000 0,01002441 0,01757328 ! G1 phase GO:0051318 27 16 0,000 0,01002441 0,01755989 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,01002441 0,01754653 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,01002441 0,01753319 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,01002441 0,01751986 ! steroid catabolic process GO:0006706 22 16 0,000 0,01002441 0,01750656 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,01002441 0,01749328 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,01002441 0,01748001 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,01002441 0,01746677 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,01002441 0,01745355 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,01002441 0,01744035 ! sperm-egg recognition GO:0035036 16 16 0,000 0,01002441 0,01742716 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,01002441 0,017414 ! nerve development GO:0021675 18 16 0,000 0,01002441 0,01740086 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,01002441 0,01738774 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,01002441 0,01737463 ! negative regulation of translation GO:0017148 22 16 0,000 0,01002441 0,01736155 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,01064789 0,0184275 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,01064789 0,01841364 ! negative regulation of defense response GO:0031348 19 17 0,000 0,01064789 0,01839981 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,01064789 0,018386 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,01064789 0,0183722 ! glycerol metabolic process GO:0006071 20 17 0,000 0,01064789 0,01835843 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,01064789 0,01834468 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,01064789 0,01833095 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,01064789 0,01831724 ! signal complex assembly GO:0007172 29 17 0,000 0,01064789 0,01830355 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,01064789 0,01828988 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,01064789 0,01827623 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,01064789 0,0182626 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,01064789 0,01824899 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,01064789 0,0182354 ! memory GO:0007613 25 17 0,000 0,01064789 0,01822184 ! keratinization GO:0031424 17 17 0,000 0,01064789 0,01820829 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,01064789 0,01819476 ! retinoid metabolic process GO:0001523 22 17 0,000 0,01064789 0,01818125 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,01064789 0,01816776 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,01064789 0,0181543 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,01064789 0,01814085 ! vacuolar transport GO:0007034 24 17 0,000 0,01064789 0,01812742 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,01064789 0,01811401 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 0,000 0,01064789 0,01810063 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,01064789 0,01808726 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,01064789 0,01807391 ! membrane budding GO:0006900 29 17 0,000 0,01064789 0,01806058 ! heme metabolic process GO:0042168 27 17 0,000 0,01064789 0,01804727 ! actin filament bundle formation GO:0051017 26 17 0,000 0,01064789 0,01803398 ! neuromuscular junction development GO:0007528 23 17 0,000 0,01064789 0,01802071 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,01064789 0,01800746 ! body fluid secretion GO:0007589 27 17 0,000 0,01064789 0,01799423 ! stem cell differentiation GO:0048863 36 17 0,000 0,01064789 0,01798102 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,01064789 0,01796783 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,01064789 0,01795465 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,01064789 0,0179415 ! sensory perception of pain GO:0019233 23 17 0,000 0,01064789 0,01792837 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,01064789 0,01791525 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,01064789 0,01790215 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,01064789 0,01788908 ! synaptogenesis GO:0007416 24 17 0,000 0,01064789 0,01787602 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,01064789 0,01786298 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,01064789 0,01784996 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,01064789 0,01783696 ! cell-cell junction organization GO:0045216 25 17 0,000 0,01064789 0,01782398 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,01064789 0,01781102 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,01064789 0,01779807 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,01064789 0,01778515 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,01064789 0,01777224 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,01064789 0,01775935 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,01064789 0,01774648 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,01127101 0,01877142 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,01127101 0,01875784 ! positive regulation of translation GO:0045727 28 18 0,000 0,01127101 0,01874428 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,01127101 0,01873073 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,01127101 0,01871721 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,01127101 0,0187037 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,01127101 0,01869022 ! cAMP metabolic process GO:0046058 33 18 0,000 0,01127101 0,01867675 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,01127101 0,01866331 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,01127101 0,01864988 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,01127101 0,01863647 ! axis specification GO:0009798 26 18 0,000 0,01127101 0,01862308 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,01127101 0,01860972 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,01127101 0,01859637 ! pancreas development GO:0031016 26 18 0,000 0,01127101 0,01858304 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,01127101 0,01856972 ! glutamine metabolic process GO:0006541 23 18 0,000 0,01127101 0,01855643 ! response to retinoic acid GO:0032526 25 18 0,000 0,01127101 0,01854316 ! pigmentation during development GO:0048066 31 18 0,000 0,01127101 0,0185299 ! central nervous system neuron development GO:0021954 30 18 0,000 0,01127101 0,01851667 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,01127101 0,01850345 ! fucose metabolic process GO:0006004 26 18 0,000 0,01127101 0,01849025 ! response to fungus GO:0009620 19 18 0,000 0,01127101 0,01847707 ! peptide cross-linking GO:0018149 31 18 0,000 0,01127101 0,01846391 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,01127101 0,01845077 ! heart process GO:0003015 27 18 0,000 0,01127101 0,01843765 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,01127101 0,01842454 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,01127101 0,01841146 ! visual learning GO:0008542 35 18 0,000 0,01127101 0,01839839 ! somitogenesis GO:0001756 24 18 0,000 0,01127101 0,01838534 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,01127101 0,01837231 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,01127101 0,0183593 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,01127101 0,01834631 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,01127101 0,01833333 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,01127101 0,01832038 ! vitamin transport GO:0051180 24 18 0,000 0,01127101 0,01830744 ! hormone transport GO:0009914 27 18 0,000 0,01127101 0,01829452 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,01127101 0,01828162 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,01127101 0,01826873 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,01127101 0,01825587 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,01127101 0,01824302 ! cell-cell recognition GO:0009988 20 18 0,000 0,01127101 0,01823019 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,01127101 0,01821738 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,01127101 0,01820459 ! regulation of glucose import GO:0046324 21 18 0,000 0,01127101 0,01819181 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,01127101 0,01817906 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,01127101 0,01816632 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,01127101 0,0181536 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,01189378 0,01914325 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,01189378 0,01912986 ! positive regulation of fibroblast proliferation GO:0048146 27 19 0,000 0,01189378 0,01911649 ! positive regulation of ossification GO:0045778 30 19 0,000 0,01189378 0,01910314 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,01189378 0,01908981 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,01189378 0,0190765 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,01189378 0,01906321 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,01189378 0,01904993 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,01189378 0,01903667 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,01189378 0,01902344 ! regeneration GO:0031099 32 19 0,000 0,01189378 0,01901022 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,01189378 0,01899701 ! response to alkaloid GO:0043279 32 19 0,000 0,01189378 0,01898383 ! sensory perception of taste GO:0050909 23 19 0,000 0,01189378 0,01897067 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,01189378 0,01895752 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 0,000 0,01189378 0,01894439 ! smooth muscle contraction GO:0006939 36 19 0,000 0,01189378 0,01893128 ! peroxisome organization GO:0007031 29 19 0,000 0,01189378 0,01891819 ! digestive system process GO:0022600 30 19 0,000 0,01189378 0,01890511 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,01189378 0,01889206 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,01189378 0,01887902 ! response to vitamin A GO:0033189 26 19 0,000 0,01189378 0,018866 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,01189378 0,018853 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,01189378 0,01884001 ! response to starvation GO:0042594 30 19 0,000 0,01189378 0,01882705 ! sex determination GO:0007530 29 19 0,000 0,01189378 0,0188141 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,01189378 0,01880117 ! plasma membrane fusion GO:0045026 23 19 0,000 0,01189378 0,01878826 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,01189378 0,01877536 ! cytolysis GO:0019835 20 19 0,000 0,01189378 0,01876248 ! renal system process GO:0003014 35 19 0,000 0,01189378 0,01874962 ! vasodilation GO:0042311 33 19 0,000 0,01189378 0,01873678 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,01189378 0,01872396 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,01189378 0,01871115 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,01189378 0,01869836 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,01189378 0,01868559 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,01189378 0,01867283 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,01189378 0,0186601 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,01189378 0,01864738 ! sarcomere organization GO:0045214 23 19 0,000 0,01189378 0,01863467 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,01189378 0,01862199 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,01189378 0,01860932 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,01189378 0,01859667 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,01189378 0,01858404 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,01189378 0,01857142 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,01189378 0,01855882 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,01189378 0,01854624 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,01189378 0,01853367 ! protein stabilization GO:0050821 26 19 0,000 0,01189378 0,01852112 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,01251619 0,01947716 ! iron ion transport GO:0006826 37 20 0,000 0,01251619 0,01946399 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,01251619 0,01945084 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,01251619 0,01943771 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,01251619 0,01942459 ! response to vitamin GO:0033273 29 20 0,000 0,01251619 0,01941149 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,01251619 0,01939841 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,01251619 0,01938535 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,01251619 0,01937231 ! spinal cord development GO:0021510 31 20 0,000 0,01251619 0,01935928 ! response to ethanol GO:0045471 37 20 0,000 0,01251619 0,01934627 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,01251619 0,01933327 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 0,000 0,01251619 0,0193203 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,01251619 0,01930734 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,01251619 0,0192944 ! chromosome condensation GO:0030261 31 20 0,000 0,01251619 0,01928148 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,01251619 0,01926857 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,01251619 0,01925568 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,01251619 0,01924281 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,01251619 0,01922996 ! pallium development GO:0021543 38 20 0,000 0,01251619 0,01921712 ! DNA modification GO:0006304 28 20 0,000 0,01251619 0,0192043 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,01251619 0,0191915 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,01251619 0,01917871 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,01251619 0,01916594 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,01251619 0,01915319 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,01251619 0,01914046 ! positive regulation of B cell activation GO:0050871 31 20 0,000 0,01251619 0,01912774 ! collagen catabolic process GO:0030574 25 20 0,000 0,01251619 0,01911504 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,01251619 0,01910235 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,01251619 0,01908969 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,01251619 0,01907704 ! alditol metabolic process GO:0019400 24 20 0,000 0,01251619 0,0190644 ! actin filament-based movement GO:0030048 34 20 0,000 0,01251619 0,01905178 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,01313825 0,01998543 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,01313825 0,01997222 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,01313825 0,01995903 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,01313825 0,01994586 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,01313825 0,0199327 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,01313825 0,01991956 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,01313825 0,01990644 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,01313825 0,01989333 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,01313825 0,01988024 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,01313825 0,01986717 ! protein amino acid acylation GO:0043543 37 21 0,000 0,01313825 0,01985412 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,01313825 0,01984108 ! vesicle docking GO:0048278 27 21 0,000 0,01313825 0,01982807 ! phototransduction GO:0007602 25 21 0,000 0,01313825 0,01981506 ! dendrite development GO:0016358 35 21 0,000 0,01313825 0,01980208 ! visual behavior GO:0007632 39 21 0,000 0,01313825 0,01978911 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,01313825 0,01977616 ! ovarian follicle development GO:0001541 30 21 0,000 0,01313825 0,01976323 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,01313825 0,01975031 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,01313825 0,01973741 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,01313825 0,01972452 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,01313825 0,01971166 ! cell aging GO:0007569 32 21 0,000 0,01313825 0,01969881 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,01313825 0,01968598 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,01313825 0,01967316 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,01313825 0,01966036 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,01313825 0,01964758 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,01313825 0,01963481 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,01313825 0,01962206 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,01313825 0,01960933 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,01313825 0,01959661 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,01313825 0,01958391 ! fatty acid transport GO:0015908 30 21 0,000 0,01313825 0,01957123 ! immunoglobulin production GO:0002377 33 21 0,000 0,01313825 0,01955856 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,01313825 0,01954591 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,01313825 0,01953327 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,01313825 0,01952065 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,01313825 0,01950805 ! cellular response to extracellular stimulus GO:0031668 32 21 0,000 0,01313825 0,01949547 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,01313825 0,0194829 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,01313825 0,01947034 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,01313825 0,01945781 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,01313825 0,01944528 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,01313825 0,01943278 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,01313825 0,01942029 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,01313825 0,01940782 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,01313825 0,01939536 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,01313825 0,01938292 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,01313825 0,0193705 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,01375995 0,02027411 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,01375995 0,02026113 ! regulation of fibroblast proliferation GO:0048145 35 22 0,000 0,01375995 0,02024816 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,01375995 0,02023522 ! viral genome replication GO:0019079 29 22 0,000 0,01375995 0,02022229 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,01375995 0,02020937 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,01375995 0,02019648 ! leukocyte adhesion GO:0007159 38 22 0,000 0,01375995 0,0201836 ! molting cycle process GO:0022404 40 22 0,000 0,01375995 0,02017073 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,01375995 0,02015788 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,01375995 0,02014505 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,01375995 0,02013224 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,01375995 0,02011944 ! vasculogenesis GO:0001570 33 22 0,000 0,01375995 0,02010666 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,01375995 0,02009389 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,01375995 0,02008114 GO:0010810|regulation of cell-substrate adhesion, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,01375995 0,02006841 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,01375995 0,02005569 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,01375995 0,02004299 ! lysosome organization GO:0007040 37 22 0,000 0,01375995 0,0200303 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,01375995 0,02001763 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,01375995 0,02000498 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,01375995 0,01999234 ! regulation of behavior GO:0050795 38 22 0,000 0,01375995 0,01997972 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,01375995 0,01996712 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,01375995 0,01995453 ! membrane depolarization GO:0051899 35 22 0,000 0,01375995 0,01994195 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,01375995 0,01992939 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,01375995 0,01991685 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,01375995 0,01990433 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,01375995 0,01989182 ! blastocyst development GO:0001824 37 22 0,000 0,01375995 0,01987932 ! neural tube closure GO:0001843 33 22 0,000 0,01375995 0,01986684 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,01375995 0,01985438 ! protein tetramerization GO:0051262 39 22 0,000 0,01375995 0,01984193 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,01438129 0,02072492 ! neuron fate commitment GO:0048663 32 23 0,000 0,01438129 0,02071194 ! embryonic pattern specification GO:0009880 31 23 0,000 0,01438129 0,02069898 ! positive regulation of cell adhesion GO:0045785 37 23 0,000 0,01438129 0,02068603 ! myelination GO:0042552 35 23 0,000 0,01438129 0,0206731 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,01438129 0,02066019 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,01438129 0,0206473 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,01438129 0,02063441 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,01438129 0,02062155 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,01438129 0,0206087 ! vesicle targeting GO:0006903 32 23 0,000 0,01438129 0,02059587 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,01438129 0,02058305 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,01438129 0,02057025 ! osteoblast differentiation GO:0001649 40 23 0,000 0,01438129 0,02055747 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,01438129 0,0205447 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,01438129 0,02053195 ! interaction with host GO:0051701 37 23 0,000 0,01438129 0,02051921 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,01438129 0,02050649 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,01438129 0,02049378 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,01438129 0,02048109 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,01438129 0,02046842 ! negative regulation of phosphorylation GO:0042326 41 23 0,000 0,01438129 0,02045576 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,01438129 0,02044312 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,01438129 0,02043049 ! cell fate determination GO:0001709 45 23 0,000 0,01438129 0,02041788 ! pentose metabolic process GO:0019321 31 23 0,000 0,01438129 0,02040528 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,01438129 0,0203927 ! spermatid development GO:0007286 33 23 0,000 0,01438129 0,02038014 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,01438129 0,02036759 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,01438129 0,02035506 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,01438129 0,02034254 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,01438129 0,02033003 ! telomere organization GO:0032200 32 23 0,000 0,01438129 0,02031755 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,01438129 0,02030507 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,01438129 0,02029262 ! regulation of amine transport GO:0051952 38 23 0,000 0,01438129 0,02028018 ! liver development GO:0001889 40 23 0,000 0,01438129 0,02026775 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,01500228 0,02112997 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,01500228 0,02111704 ! initiation of viral infection GO:0019059 42 24 0,000 0,01500228 0,02110412 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,01500228 0,02109122 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,01500228 0,02107834 ! superoxide metabolic process GO:0006801 32 24 0,000 0,01500228 0,02106547 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,01500228 0,02105262 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! insulin receptor signaling pathway GO:0008286 40 24 0,000 0,01500228 0,02103978 ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,01500228 0,02102696 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,01500228 0,02101415 ! sperm motility GO:0030317 27 24 0,000 0,01500228 0,02100136 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,01500228 0,02098859 ! vacuole organization GO:0007033 39 24 0,000 0,01500228 0,02097583 ! receptor metabolic process GO:0043112 37 24 0,000 0,01500228 0,02096308 ! neural crest cell development GO:0014032 39 24 0,000 0,01500228 0,02095036 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,01500228 0,02093764 ! primary neural tube formation GO:0014020 35 24 0,000 0,01500228 0,02092495 ! negative regulation of cell development GO:0010721 56 24 0,000 0,01500228 0,02091226 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,01500228 0,0208996 ! base-excision repair GO:0006284 31 24 0,000 0,01500228 0,02088695 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,01500228 0,02087431 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,01500228 0,02086169 ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,01500228 0,02084909 ! glutathione metabolic process GO:0006749 29 24 0,000 0,01500228 0,0208365 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,01500228 0,02082392 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,01500228 0,02081136 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,01500228 0,02079882 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,01562291 0,0216462 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,01562291 0,02163317 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,01562291 0,02162015 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,01562291 0,02160715 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,01562291 0,02159416 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,01562291 0,02158119 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 0,000 0,01562291 0,02156824 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,01562291 0,0215553 ! peptide transport GO:0015833 43 25 0,000 0,01562291 0,02154238 ! male gonad development GO:0008584 33 25 0,000 0,01562291 0,02152947 ! iron ion homeostasis GO:0055072 39 25 0,000 0,01562291 0,02151658 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,01562291 0,0215037 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,01562291 0,02149084 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,01562291 0,021478 ! phospholipid transport GO:0015914 35 25 0,000 0,01562291 0,02146517 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,01562291 0,02145235 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,01562291 0,02143955 ! detection of light stimulus GO:0009583 30 25 0,000 0,01562291 0,02142677 ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,01562291 0,021414 ! leukocyte proliferation GO:0070661 39 25 0,000 0,01562291 0,02140124 GO:0032943|mononuclear cell proliferation, ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,01624318 0,02223769 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,01624318 0,02222446 ! translational initiation GO:0006413 43 26 0,000 0,01624318 0,02221125 ! regulation of pH GO:0006885 36 26 0,000 0,01624318 0,02219805 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 0,000 0,01624318 0,02218487 ! circadian rhythm GO:0007623 42 26 0,000 0,01624318 0,0221717 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,01624318 0,02215855 ! post-embryonic development GO:0009791 42 26 0,000 0,01624318 0,02214542 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,01624318 0,0221323 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,01624318 0,0221192 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,01624318 0,02210611 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,01624318 0,02209303 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,01624318 0,02207998 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,01624318 0,02206693 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,01624318 0,02205391 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,01624318 0,0220409 ! regulation of coagulation GO:0050818 39 26 0,000 0,01624318 0,0220279 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,0168631 0,02285512 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,0168631 0,02284166 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,0168631 0,02282821 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,0168631 0,02281479 ! membrane docking GO:0022406 39 27 0,000 0,0168631 0,02280137 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,0168631 0,02278798 ! catechol metabolic process GO:0009712 43 27 0,000 0,0168631 0,0227746 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,0168631 0,02276123 ! acute-phase response GO:0006953 42 27 0,000 0,0168631 0,02274788 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,0168631 0,02273455 ! myofibril assembly GO:0030239 36 27 0,000 0,0168631 0,02272123 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,0168631 0,02270793 ! response to ionizing radiation GO:0010212 47 27 0,000 0,0168631 0,02269464 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,0168631 0,02268137 ! natural killer cell activation GO:0030101 35 27 0,000 0,0168631 0,02266811 ! lipid oxidation GO:0034440 38 27 0,000 0,0168631 0,02265487 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,0168631 0,02264164 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,0168631 0,02262843 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,0168631 0,02261524 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,0168631 0,02260206 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,0168631 0,0225889 ! gene silencing GO:0016458 41 27 0,000 0,0168631 0,02257575 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,01748267 0,02339159 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,01748267 0,02337799 ! phenol metabolic process GO:0018958 44 28 0,000 0,01748267 0,0233644 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,01748267 0,02335083 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,01748267 0,02333728 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,01748267 0,02332374 ! cell junction assembly GO:0034329 56 28 0,000 0,01748267 0,02331022 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,01748267 0,02329672 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,01748267 0,02328323 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,01748267 0,02326975 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,01748267 0,0232563 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,01748267 0,02324285 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,01748267 0,02322943 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,01748267 0,02321601 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,01748267 0,02320262 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,01748267 0,02318924 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,01748267 0,02317587 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,01748267 0,02316252 ! mesoderm formation GO:0001707 46 28 0,000 0,01748267 0,02314919 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,01748267 0,02313587 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,01748267 0,02312256 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,01748267 0,02310927 ! ensheathment of neurons GO:0007272 43 28 0,000 0,01748267 0,023096 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,01748267 0,02308274 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,01748267 0,0230695 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,01748267 0,02305627 ! neural tube formation GO:0001841 41 28 0,000 0,01748267 0,02304306 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,01748267 0,02302986 ! placenta development GO:0001890 37 28 0,000 0,01748267 0,02301668 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,01810188 0,02381826 ! regulation of innate immune response GO:0045088 38 29 0,000 0,01810188 0,02380464 ! ovulation cycle process GO:0022602 41 29 0,000 0,01810188 0,02379104 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,01810188 0,02377745 ! protein targeting to membrane GO:0006612 53 29 0,000 0,01810188 0,02376388 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,01810188 0,02375032 ! mismatch repair GO:0006298 34 29 0,000 0,01810188 0,02373678 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,01810188 0,02372326 ! muscle cell development GO:0055001 38 29 0,000 0,01810188 0,02370975 ! formation of primary germ layer GO:0001704 48 29 0,000 0,01810188 0,02369625 ! telencephalon development GO:0021537 52 29 0,000 0,01810188 0,02368278 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,01810188 0,02366931 ! eye morphogenesis GO:0048592 51 29 0,000 0,01810188 0,02365586 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,01810188 0,02364243 ! tissue homeostasis GO:0001894 42 29 0,000 0,01810188 0,02362901 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,01872073 0,02442296 ! collagen metabolic process GO:0032963 40 30 0,000 0,01872073 0,02440912 ! organic anion transport GO:0015711 51 30 0,000 0,01872073 0,02439529 ! cholesterol transport GO:0030301 46 30 0,000 0,01872073 0,02438148 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,01872073 0,02436768 ! spliceosome assembly GO:0000245 49 30 0,000 0,01872073 0,02435389 ! spindle organization GO:0007051 37 30 0,000 0,01872073 0,02434013 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,01872073 0,02432638 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,01872073 0,02431264 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,01872073 0,02429892 ! ceramide metabolic process GO:0006672 43 30 0,000 0,01872073 0,02428521 ! ovulation cycle GO:0042698 43 30 0,000 0,01872073 0,02427153 ! hindbrain development GO:0030902 45 30 0,000 0,01872073 0,02425785 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,01872073 0,02424419 ! adult locomotory behavior GO:0008344 47 30 0,000 0,01872073 0,02423055 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,01872073 0,02421692 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,01872073 0,02420331 ! response to heat GO:0009408 41 30 0,000 0,01872073 0,02418971 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,01872073 0,02417613 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,01872073 0,02416256 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,01933923 0,02494685 ! negative regulation of secretion GO:0051048 49 31 0,000 0,01933923 0,02493287 ! mammary gland development GO:0030879 57 31 0,000 0,01933923 0,0249189 ! glial cell differentiation GO:0010001 55 31 0,000 0,01933923 0,02490495 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,01933923 0,02489101 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,01933923 0,02487709 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,01933923 0,02486318 ! odontogenesis GO:0042476 50 31 0,000 0,01933923 0,02484929 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,01933923 0,02483542 ! segmentation GO:0035282 41 31 0,000 0,01933923 0,02482156 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,01933923 0,02480772 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,01933923 0,02479389 ! metanephros development GO:0001656 58 31 0,000 0,01933923 0,02478008 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,01933923 0,02476628 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,01933923 0,0247525 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,01933923 0,02473873 ! cell fate specification GO:0001708 37 31 0,000 0,01933923 0,02472498 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,01933923 0,02471124 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,01933923 0,02469752 ! RNA modification GO:0009451 40 31 0,000 0,01933923 0,02468382 ! regulation of muscle development GO:0048634 48 32 0,000 0,01995738 0,02545867 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,01995738 0,02544455 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,01995738 0,02543046 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,01995738 0,02541638 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,01995738 0,02540231 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,01995738 0,02538826 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,01995738 0,02537423 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,01995738 0,02536021 ! peripheral nervous system development GO:0007422 53 32 0,000 0,01995738 0,0253462 ! regulation of protein stability GO:0031647 48 32 0,000 0,01995738 0,02533221 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,01995738 0,02531824 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,01995738 0,02530429 ! cytokine production GO:0001816 44 32 0,000 0,01995738 0,02529034 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,01995738 0,02527642 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,01995738 0,02526251 ! vesicle localization GO:0051648 47 32 0,000 0,01995738 0,02524861 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,02057517 0,02601589 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,02057517 0,02600159 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,02057517 0,02598731 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,02057517 0,02597305 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,02057517 0,0259588 ! sister chromatid segregation GO:0000819 46 33 0,000 0,02057517 0,02594457 ! ear morphogenesis GO:0042471 42 33 0,000 0,02057517 0,02593035 ! actomyosin structure organization GO:0031032 43 33 0,000 0,02057517 0,02591615 ! cell junction organization GO:0034330 63 33 0,000 0,02057517 0,02590197 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,02057517 0,0258878 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,02057517 0,02587364 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,02057517 0,02585951 GO:0042593|glucose homeostasis, ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,02057517 0,02584538 ! female gonad development GO:0008585 49 33 0,000 0,02057517 0,02583127 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,02057517 0,02581718 ! positive regulation of cell development GO:0010720 54 33 0,000 0,02057517 0,02580311 ! lipid homeostasis GO:0055088 55 33 0,000 0,02057517 0,02578904 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,02057517 0,025775 ! regulation of proteolysis GO:0030162 50 33 0,000 0,02057517 0,02576097 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,02057517 0,02574695 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,02057517 0,02573295 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,02057517 0,02571896 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,02119261 0,02647637 ! mRNA catabolic process GO:0006402 48 34 0,000 0,02119261 0,026462 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,02119261 0,02644764 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,02119261 0,0264333 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,02119261 0,02641897 ! feeding behavior GO:0007631 45 34 0,000 0,02119261 0,02640466 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,02119261 0,02639036 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,02119261 0,02637608 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,02119261 0,02636182 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,02119261 0,02634757 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,02119261 0,02633333 ! neuron migration GO:0001764 46 34 0,000 0,02119261 0,02631912 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,02119261 0,02630491 ! female gamete generation GO:0007292 43 34 0,000 0,02119261 0,02629072 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,02119261 0,02627655 ! polyol metabolic process GO:0019751 44 34 0,000 0,02119261 0,02626239 ! aerobic respiration GO:0009060 47 34 0,000 0,02119261 0,02624825 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,02119261 0,02623412 ! cellular response to insulin stimulus GO:0032869 52 34 0,000 0,02119261 0,02622001 ! embryonic organ development GO:0048568 45 34 0,000 0,02119261 0,02620592 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,02119261 0,02619183 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,02180969 0,02694001 ! Notch signaling pathway GO:0007219 56 35 0,000 0,02180969 0,02692555 ! regulation of intracellular protein transport GO:0033157 59 35 0,000 0,02180969 0,0269111 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,02180969 0,02689667 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,02180969 0,02688226 GO:0032313|regulation of Rab GTPase activity, ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,02180969 0,02686786 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,02180969 0,02685348 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,02180969 0,02683911 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,02180969 0,02682476 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,02180969 0,02681042 ! glycogen metabolic process GO:0005977 48 35 0,000 0,02180969 0,0267961 ! pigment metabolic process GO:0042440 61 35 0,000 0,02180969 0,02678179 ! positive regulation of leukocyte proliferation GO:0070665 50 35 0,000 0,02180969 0,0267675 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,02242642 0,02750975 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 0,000 0,02242642 0,02749508 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,02242642 0,02748043 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,02242642 0,0274658 ! negative regulation of binding GO:0051100 58 36 0,000 0,02242642 0,02745118 ! organic ether metabolic process GO:0018904 46 36 0,000 0,02242642 0,02743658 ! tissue remodeling GO:0048771 62 36 0,000 0,02242642 0,027422 ! neural tube development GO:0021915 50 36 0,000 0,02242642 0,02740743 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,02242642 0,02739287 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,02242642 0,02737833 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,02242642 0,02736381 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,02242642 0,0273493 ! glucan metabolic process GO:0044042 49 36 0,000 0,02242642 0,0273348 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,0230428 0,02807121 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,0230428 0,02805635 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,0230428 0,0280415 ! learning GO:0007612 67 37 0,000 0,0230428 0,02802667 ! ion transmembrane transport GO:0034220 56 37 0,000 0,0230428 0,02801186 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,0230428 0,02799706 ! regulation of protein secretion GO:0050708 51 37 0,000 0,0230428 0,02798228 ! amino acid activation GO:0043038 52 37 0,000 0,0230428 0,02796752 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,0230428 0,02795276 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,02365882 0,02868492 ! gliogenesis GO:0042063 71 38 0,000 0,02365882 0,02866981 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,02365882 0,02865471 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,02365882 0,02863963 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,02365882 0,02862456 ! phagocytosis GO:0006909 60 38 0,000 0,02365882 0,02860951 ! mesenchymal cell development GO:0014031 64 38 0,000 0,02365882 0,02859448 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 0,000 0,02365882 0,02857946 ! maintenance of location in cell GO:0051651 69 38 0,000 0,02365882 0,02856446 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,02427449 0,02929241 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,02427449 0,02927705 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,02427449 0,02926171 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,02427449 0,02924638 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,02427449 0,02923107 ! regulation of epithelial cell proliferation GO:0050678 71 39 0,000 0,02427449 0,02921577 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,02427449 0,02920049 ! male sex differentiation GO:0046661 53 39 0,000 0,02427449 0,02918523 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,02427449 0,02916998 ! chromatin remodeling GO:0006338 68 39 0,000 0,02427449 0,02915475 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,02427449 0,02913953 ! JNK cascade GO:0007254 54 39 0,000 0,02427449 0,02912433 ! developmental growth GO:0048589 62 39 0,000 0,02427449 0,02910914 ! cell growth GO:0016049 61 39 0,000 0,02427449 0,02909397 ! synapse organization GO:0050808 55 39 0,000 0,02427449 0,02907882 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,02488981 0,0298004 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,02488981 0,02978489 ! regulation of tube size GO:0035150 60 40 0,000 0,02488981 0,02976941 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,02488981 0,02975393 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,02488981 0,02973848 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,02488981 0,02972304 ! peptide metabolic process GO:0006518 56 40 0,000 0,02488981 0,02970761 ! inner ear development GO:0048839 57 40 0,000 0,02488981 0,0296922 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,02488981 0,02967681 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,02488981 0,02966143 ! B cell differentiation GO:0030183 62 40 0,000 0,02488981 0,02964607 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,02488981 0,02963073 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,02488981 0,0296154 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,02488981 0,02960009 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,02550478 0,03031575 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,02550478 0,0303001 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,02550478 0,03028445 ! glucose transport GO:0015758 52 41 0,000 0,02550478 0,03026883 ! endosome transport GO:0016197 71 41 0,000 0,02550478 0,03025322 ! striated muscle contraction GO:0006941 62 41 0,000 0,02550478 0,03023762 ! positive regulation of DNA binding GO:0043388 57 41 0,000 0,02550478 0,03022204 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,02550478 0,03020648 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,02550478 0,03019093 ! biopolymer methylation GO:0043414 62 41 0,000 0,02550478 0,0301754 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,02550478 0,03015989 ! mitochondrial transport GO:0006839 60 42 0,000 0,02611939 0,03087081 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,02611939 0,03085495 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 0,000 0,02611939 0,03083911 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,02611939 0,03082329 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,02611939 0,03080748 ! hexose transport GO:0008645 54 42 0,000 0,02611939 0,03079169 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,02611939 0,03077592 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,02611939 0,03076016 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,02611939 0,03074442 ! excretion GO:0007588 63 42 0,000 0,02611939 0,03072869 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,02611939 0,03071298 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,02611939 0,03069729 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,02611939 0,03068161 ! regulation of cell shape GO:0008360 78 42 0,000 0,02611939 0,03066595 ! positive regulation of binding GO:0051099 59 43 0,000 0,02673365 0,03137112 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,02673365 0,03135512 ! leukocyte migration GO:0050900 60 43 0,000 0,02673365 0,03133914 ! neuromuscular process GO:0050905 79 43 0,000 0,02673365 0,03132317 ! activation of caspase activity GO:0006919 65 43 0,000 0,02673365 0,03130723 ! tRNA processing GO:0008033 49 43 0,000 0,02673365 0,03129129 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,02673365 0,03127538 ! vesicle organization GO:0016050 79 43 0,000 0,02673365 0,03125948 ! response to insulin stimulus GO:0032868 63 43 0,000 0,02673365 0,03124359 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,02673365 0,03122772 ! methylation GO:0032259 64 43 0,000 0,02673365 0,03121187 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,02734756 0,03191242 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,02734756 0,03189624 ! glycolysis GO:0006096 53 44 0,000 0,02734756 0,03188007 ! regulation of action potential GO:0001508 71 44 0,000 0,02734756 0,03186392 ! regulation of ion transport GO:0043269 57 44 0,000 0,02734756 0,03184779 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,02734756 0,03183167 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,02734756 0,03181557 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,02734756 0,03179948 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,02734756 0,03178341 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,02734756 0,03176736 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,02734756 0,03175133 ! RNA catabolic process GO:0006401 64 45 0,000 0,02796111 0,0324473 ! positive regulation of defense response GO:0031349 59 45 0,000 0,02796111 0,03243094 ! regulation of translational initiation GO:0006446 64 45 0,000 0,02796111 0,03241459 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,02796111 0,03239826 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,02796111 0,03238195 ! cell recognition GO:0008037 58 45 0,000 0,02796111 0,03236565 ! cell maturation GO:0048469 60 45 0,000 0,02796111 0,03234937 ! protein amino acid autophosphorylation GO:0046777 80 45 0,000 0,02796111 0,03233311 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,02857431 0,03302559 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,02857431 0,033009 ! cell redox homeostasis GO:0045454 63 46 0,000 0,02857431 0,03299243 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,02857431 0,03297588 ! regulation of ossification GO:0030278 71 46 0,000 0,02857431 0,03295934 ! histone modification GO:0016570 68 46 0,000 0,02857431 0,03294282 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,02857431 0,03292631 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,02918717 0,03361566 ! viral infectious cycle GO:0019058 71 47 0,000 0,02918717 0,03359884 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,02918717 0,03358203 ! endocrine system development GO:0035270 83 47 0,000 0,02918717 0,03356524 ! covalent chromatin modification GO:0016569 75 47 0,000 0,02918717 0,03354847 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,02918717 0,03353171 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,02918717 0,03351497 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,02918717 0,03349824 ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,02918717 0,03348154 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,02918717 0,03346485 ! chloride transport GO:0006821 67 48 0,000 0,02979967 0,03415009 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,02979967 0,03413308 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 0,000 0,02979967 0,03411609 ! response to temperature stimulus GO:0009266 62 48 0,000 0,02979967 0,03409912 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,02979967 0,03408216 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,02979967 0,03406522 ! gastrulation GO:0007369 73 48 0,000 0,02979967 0,0340483 ! heart morphogenesis GO:0003007 65 48 0,000 0,02979967 0,0340314 ! regulation of DNA replication GO:0006275 75 48 0,000 0,02979967 0,03401451 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,02979967 0,03399763 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,02979967 0,03398078 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,02979967 0,03396394 ! regulation of endocytosis GO:0030100 63 48 0,000 0,02979967 0,03394712 ! nuclear export GO:0051168 69 48 0,000 0,02979967 0,03393031 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,02979967 0,03391352 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,02979967 0,03389675 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,03041181 0,03457596 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,03041181 0,03455888 ! sensory perception of smell GO:0007608 61 49 0,000 0,03041181 0,03454181 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,03041181 0,03452476 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,03041181 0,03450773 ! RNA elongation GO:0006354 62 49 0,000 0,03041181 0,03449072 ! regulation of intracellular transport GO:0032386 78 49 0,000 0,03041181 0,03447372 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,03041181 0,03445674 ! germ cell development GO:0007281 68 49 0,000 0,03041181 0,03443977 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,03041181 0,03442282 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,03041181 0,03440589 ! cartilage development GO:0051216 70 49 0,000 0,03041181 0,03438897 ! maintenance of location GO:0051235 84 49 0,000 0,03041181 0,03437208 ! regulation of actin filament length GO:0030832 72 50 0,000 0,03102361 0,03504632 ! ear development GO:0043583 72 50 0,000 0,03102361 0,03502912 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,03102361 0,03501193 ! membrane fusion GO:0006944 80 50 0,000 0,03102361 0,03499476 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,03102361 0,0349776 ! lipid modification GO:0030258 73 50 0,000 0,03102361 0,03496046 ! positive regulation of growth GO:0045927 67 50 0,000 0,03102361 0,03494334 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,03102361 0,03492624 ! proton transport GO:0015992 75 50 0,000 0,03102361 0,03490915 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,03102361 0,03489208 ! positive regulation of secretion GO:0051047 71 51 0,000 0,03163506 0,03556238 ! hydrogen transport GO:0006818 77 51 0,000 0,03163506 0,03554501 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,03163506 0,03552765 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 0,000 0,03163506 0,03551032 ! positive regulation of cell migration GO:0030335 92 51 0,000 0,03163506 0,03549299 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,03163506 0,03547569 ! adult behavior GO:0030534 80 51 0,000 0,03163506 0,0354584 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,03163506 0,03544113 ! transition metal ion transport GO:0000041 74 52 0,000 0,03224616 0,03610816 ! regulation of cellular component size GO:0032535 74 52 0,000 0,03224616 0,03609059 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,03224616 0,03607303 ! aging GO:0007568 79 52 0,000 0,03224616 0,0360555 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,03224616 0,03603798 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,03224616 0,03602047 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,0328569 0,03668489 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,0328569 0,03666709 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,0328569 0,03664931 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,0328569 0,03663154 ! kidney development GO:0001822 90 53 0,000 0,0328569 0,03661379 ! single fertilization GO:0007338 59 53 0,000 0,0328569 0,03659606 ! cell projection assembly GO:0030031 76 53 0,000 0,0328569 0,03657835 ! amino acid transport GO:0006865 84 54 0,000 0,0334673 0,03723985 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,0334673 0,03722185 ! glucose catabolic process GO:0006007 66 54 0,000 0,0334673 0,03720386 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,0334673 0,03718588 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,0334673 0,03716793 ! detection of external stimulus GO:0009581 66 54 0,000 0,0334673 0,03714999 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,0334673 0,03713207 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,0334673 0,03711417 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,0334673 0,03709628 ! exocytosis GO:0006887 74 55 0,000 0,03407734 0,03775428 ! mesoderm development GO:0007498 76 55 0,000 0,03407734 0,0377361 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,03407734 0,03771794 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,03407734 0,0376998 ! DNA damage response, signal transduction GO:0042770 96 56 0,000 0,03468703 0,03835586 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,03468703 0,03833742 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,03468703 0,03831901 ! positive regulation of cell motion GO:0051272 99 56 0,000 0,03468703 0,03830061 ! carbohydrate transport GO:0008643 74 57 0,000 0,03529638 0,03895474 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,03529638 0,03893605 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 0,000 0,03529638 0,03891739 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,03529638 0,03889874 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,03529638 0,03888011 ! camera-type eye development GO:0043010 88 57 0,000 0,03529638 0,0388615 ! secondary metabolic process GO:0019748 84 57 0,000 0,03529638 0,03884291 ! response to peptide hormone stimulus GO:0043434 84 57 0,000 0,03529638 0,03882433 ! developmental maturation GO:0021700 75 57 0,000 0,03529638 0,03880577 ! gonad development GO:0008406 79 57 0,000 0,03529638 0,03878723 ! viral reproductive process GO:0022415 87 58 0,000 0,03590537 0,03943761 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,03590537 0,03941879 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,03590537 0,03939998 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,03590537 0,03938119 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,03651402 0,04002967 ! activation of MAPK activity GO:0000187 84 59 0,000 0,03651402 0,0400106 ! lung development GO:0030324 94 59 0,000 0,03651402 0,03999155 ! actin filament organization GO:0007015 95 59 0,000 0,03651402 0,03997251 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,03651402 0,0399535 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,03651402 0,0399345 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,03712232 0,04058048 ! phosphoinositide metabolic process GO:0030384 87 60 0,000 0,03712232 0,0405612 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,03712232 0,04054194 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,03712232 0,0405227 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,03712232 0,04050348 ! regulation of heart contraction GO:0008016 91 60 0,000 0,03712232 0,04048427 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,03712232 0,04046508 ! fertilization GO:0009566 68 60 0,000 0,03712232 0,04044592 ! regulation of homeostatic process GO:0032844 105 60 0,000 0,03712232 0,04042677 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,03773026 0,04106938 ! cell-matrix adhesion GO:0007160 114 61 0,000 0,03773026 0,04104996 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,03773026 0,04103055 ! urogenital system development GO:0001655 101 61 0,000 0,03773026 0,04101116 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,03773026 0,04099178 ! extracellular matrix organization GO:0030198 103 61 0,000 0,03773026 0,04097243 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,03773026 0,04095309 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! amine catabolic process GO:0009310 90 62 0,000 0,03833786 0,04159296 ! neurotransmitter transport GO:0006836 81 62 0,000 0,03833786 0,04157335 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,03833786 0,04155376 ! negative regulation of cell growth GO:0030308 106 62 0,000 0,03833786 0,04153419 ! respiratory tube development GO:0030323 99 62 0,000 0,03833786 0,04151463 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,03833786 0,0414951 ! regulation of transcription factor activity GO:0051090 97 63 0,000 0,03894511 0,04213253 GO:0090046|regulation of transcription regulator activity, ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,03894511 0,04211272 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 0,000 0,03894511 0,04209293 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 0,000 0,03894511 0,04207316 ! viral reproduction GO:0016032 92 63 0,000 0,03894511 0,04205341 ! regulation of lipase activity GO:0060191 109 63 0,000 0,03894511 0,04203367 ! negative regulation of cell size GO:0045792 108 64 0,000 0,03955201 0,04266868 ! appendage morphogenesis GO:0035107 93 64 0,000 0,03955201 0,04264868 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,03955201 0,04262869 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,03955201 0,04260872 ! hexose catabolic process GO:0019320 82 64 0,000 0,03955201 0,04258878 ! respiratory system development GO:0060541 100 64 0,000 0,03955201 0,04256885 ! adaptive immune response GO:0002250 94 64 0,000 0,03955201 0,04254894 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 90 65 0,000 0,04015856 0,04318125 ! appendage development GO:0048736 94 65 0,000 0,04015856 0,04316107 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 0,000 0,04015856 0,04314091 ! defense response to bacterium GO:0042742 73 65 0,000 0,04015856 0,04312077 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,04015856 0,04310065 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,04015856 0,04308055 ! activation of immune response GO:0002253 83 65 0,000 0,04015856 0,04306047 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,04076477 0,04369011 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,04076477 0,04366976 ! antigen processing and presentation GO:0019882 96 66 0,000 0,04076477 0,04364943 ! axon guidance GO:0007411 99 66 0,000 0,04076477 0,04362911 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,04076477 0,04360882 ! regulation of immune effector process GO:0002697 101 66 0,000 0,04076477 0,04358855 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,04137062 0,04421582 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,04137062 0,04419528 ! acute inflammatory response GO:0002526 92 68 0,000 0,04197613 0,04482131 ! learning or memory GO:0007611 123 68 0,000 0,04197613 0,04480051 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,04197613 0,04477973 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,04197613 0,04475897 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,04197613 0,04473823 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,04197613 0,04471751 ! rhythmic process GO:0048511 105 68 0,000 0,04197613 0,04469681 ! inorganic anion transport GO:0015698 93 68 0,000 0,04197613 0,04467612 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,04258129 0,04529925 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,04258129 0,0452783 ! response to drug GO:0042493 108 69 0,000 0,04258129 0,04525738 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,04318611 0,045879 ! humoral immune response GO:0006959 86 70 0,000 0,04318611 0,04585782 ! eye development GO:0001654 111 70 0,000 0,04318611 0,04583666 ! amine transport GO:0015837 101 70 0,000 0,04318611 0,04581552 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,04318611 0,0457944 ! regulation of catabolic process GO:0009894 106 70 0,000 0,04318611 0,04577329 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,04379057 0,04639259 ! muscle cell differentiation GO:0042692 104 71 0,000 0,04379057 0,04637123 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,04379057 0,04634989 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,04379057 0,04632857 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,04379057 0,04630727 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,04379057 0,04628599 ! response to hypoxia GO:0001666 132 72 0,000 0,04439469 0,04690298 ! negative regulation of organelle organization GO:0010639 115 72 0,000 0,04439469 0,04688144 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,04439469 0,04685993 ! negative regulation of transport GO:0051051 116 73 0,000 0,04499846 0,04747544 ! regulation of blood pressure GO:0008217 107 73 0,000 0,04499846 0,04745367 ! tube morphogenesis GO:0035239 118 73 0,000 0,04499846 0,04743192 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,04499846 0,0474102 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,04499846 0,04738849 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,04560189 0,04800198 ! response to oxygen levels GO:0070482 137 74 0,000 0,04560189 0,04798003 ! digestion GO:0007586 97 74 0,000 0,04560189 0,04795809 ! protein import into nucleus GO:0006606 118 74 0,000 0,04560189 0,04793617 ! cellular response to hormone stimulus GO:0032870 109 74 0,000 0,04560189 0,04791427 ! positive regulation of lymphocyte activation GO:0051251 108 74 0,000 0,04560189 0,04789239 ! blood coagulation GO:0007596 116 75 0,000 0,04620496 0,04850361 GO:0050817|coagulation, ! negative regulation of growth GO:0045926 123 75 0,000 0,04620496 0,04848148 ! response to nutrient GO:0007584 104 75 0,000 0,04620496 0,04845938 ! nuclear import GO:0051170 121 75 0,000 0,04620496 0,04843729 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,04620496 0,04841522 ! amine biosynthetic process GO:0009309 97 76 0,000 0,04680769 0,04902445 ! tRNA metabolic process GO:0006399 95 76 0,000 0,04680769 0,04900214 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,04680769 0,04897984 ! regulation of protein transport GO:0051223 114 76 0,000 0,04680769 0,04895757 GO:0070201|regulation of establishment of protein localization, ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,04741008 0,04956508 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,04741008 0,04954256 ! regulation of DNA binding GO:0051101 119 77 0,000 0,04741008 0,04952006 ! gland development GO:0048732 148 77 0,000 0,04741008 0,04949759 ! sex differentiation GO:0007548 105 77 0,000 0,04741008 0,04947513 ! protein ubiquitination GO:0016567 125 77 0,000 0,04741008 0,04945269 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,04741008 0,04943027 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,04741008 0,04940788 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,04741008 0,0493855 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,04801212 0,04998998 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,04801212 0,04996736 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,04861381 0,05057068 ! cellular respiration GO:0045333 107 79 0,000 0,04861381 0,05054782 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,04861381 0,05052497 ! T cell activation GO:0042110 134 79 0,000 0,04861381 0,05050215 ! regulation of lyase activity GO:0051339 133 79 0,000 0,04861381 0,05047935 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,04861381 0,05045657 ! chromatin assembly GO:0031497 102 80 0,000 0,04921516 0,05105768 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,04921516 0,05103466 ! protein localization in nucleus GO:0034504 133 80 0,000 0,04921516 0,05101166 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,04921516 0,05098868 ! forebrain development GO:0030900 131 80 0,000 0,04921516 0,05096572 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,04981616 0,05156488 ! hemostasis GO:0007599 125 81 0,000 0,04981616 0,05154169 ! mRNA transport GO:0051028 121 81 0,000 0,04981616 0,05151851 ! regulation of neurological system process GO:0031644 122 81 0,000 0,04981616 0,05149536 ! vitamin metabolic process GO:0006766 103 81 0,000 0,04981616 0,05147222 ! positive regulation of cell activation GO:0050867 120 81 0,000 0,04981616 0,05144911 GO:0002696|positive regulation of leukocyte activation, ! ossification GO:0001503 134 82 0,000 0,05041682 0,05204609 GO:0060348|bone development, ! detection of stimulus GO:0051606 108 82 0,000 0,05041682 0,05202274 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,05101713 0,05261856 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,05101713 0,05259498 ! regulation of cell adhesion GO:0030155 159 83 0,000 0,05101713 0,05257141 ! regulation of defense response GO:0031347 117 84 0,000 0,05161709 0,05316584 ! microtubule cytoskeleton organization GO:0000226 120 84 0,000 0,05161709 0,05314204 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,05161709 0,05311826 ! sterol metabolic process GO:0016125 120 84 0,000 0,05161709 0,05309451 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,05221672 0,05368728 ! rRNA metabolic process GO:0016072 107 85 0,000 0,05221672 0,05366329 GO:0006364|rRNA processing, ! positive regulation of MAP kinase activity GO:0043406 121 85 0,000 0,05221672 0,05363932 ! transcription initiation GO:0006352 118 85 0,000 0,05221672 0,05361538 ! anterior/posterior pattern formation GO:0009952 124 85 0,000 0,05221672 0,05359145 ! regulation of protein localization GO:0032880 132 85 0,000 0,05221672 0,05356755 ! regulation of membrane potential GO:0042391 128 85 0,000 0,05221672 0,05354367 ! negative regulation of multicellular organismal process GO:0051241 133 85 0,000 0,05221672 0,05351981 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,05281599 0,05410993 ! cell cycle arrest GO:0007050 150 86 0,000 0,05281599 0,05408583 ! nucleosome organization GO:0034728 114 87 0,000 0,05341492 0,05467482 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,05341492 0,0546505 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,05341492 0,0546262 ! skeletal muscle tissue development GO:0007519 123 87 0,000 0,05341492 0,05460192 GO:0060538|skeletal muscle organ development, ! female pregnancy GO:0007565 130 87 0,000 0,05341492 0,05457767 ! Wnt receptor signaling pathway GO:0016055 130 87 0,000 0,05341492 0,05455343 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,05401351 0,05514029 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,05401351 0,05511583 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,05401351 0,05509139 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,05401351 0,05506697 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 0,000 0,05401351 0,05504257 ! regulation of neurogenesis GO:0050767 153 89 0,000 0,05461176 0,05562756 ! reproductive developmental process GO:0003006 127 89 0,000 0,05461176 0,05560294 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,05461176 0,05557834 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,05461176 0,05555375 ! leukocyte differentiation GO:0002521 143 90 0,000 0,05520966 0,05613714 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,05520966 0,05611233 ! hormone metabolic process GO:0042445 121 90 0,000 0,05520966 0,05608755 ! RNA localization GO:0006403 135 91 0,000 0,05580721 0,05666958 ! ATP metabolic process GO:0046034 137 91 0,000 0,05580721 0,05664457 ! response to virus GO:0009615 122 91 0,000 0,05580721 0,05661958 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,05640442 0,05720025 ! glycerophospholipid metabolic process GO:0006650 130 92 0,000 0,05640442 0,05717504 ! positive regulation of immune response GO:0050778 121 92 0,000 0,05640442 0,05714986 ! sulfur metabolic process GO:0006790 118 92 0,000 0,05640442 0,05712469 ! regulation of cytoskeleton organization GO:0051493 154 93 0,000 0,05700129 0,05770377 ! peptidyl-amino acid modification GO:0018193 147 93 0,000 0,05700129 0,05767839 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,05700129 0,05765302 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,05700129 0,05762768 ! electron transport chain GO:0022900 123 94 0,000 0,05759782 0,05820518 ! response to oxidative stress GO:0006979 141 94 0,000 0,05759782 0,05817962 ! regulation of binding GO:0051098 151 95 0,000 0,058194 0,05875602 ! angiogenesis GO:0001525 149 95 0,000 0,058194 0,05873023 ! carboxylic acid transport GO:0046942 147 95 0,000 0,058194 0,05870448 GO:0015849|organic acid transport, ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,05878984 0,05927954 ! in utero embryonic development GO:0001701 147 96 0,000 0,05878984 0,05925357 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,05878984 0,05922761 ! regulation of cellular component biogenesis GO:0044087 158 96 0,000 0,05878984 0,05920168 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,05878984 0,05917577 ! protein maturation GO:0051604 129 96 0,000 0,05878984 0,05914988 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,05938534 0,0597229 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,05938534 0,0596968 ! calcium ion transport GO:0006816 167 99 0,000 0,06057531 0,06086641 ! extracellular structure organization GO:0043062 156 99 0,000 0,06057531 0,06083983 ! protein import GO:0017038 156 99 0,000 0,06057531 0,06081327 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 0,000 0,06057531 0,06078674 ! regulation of translation GO:0006417 151 100 0,000 0,06116978 0,06135651 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,06116978 0,06132977 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,06116978 0,06130304 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,06116978 0,06127634 ! divalent metal ion transport GO:0070838 171 100 0,000 0,06116978 0,06124967 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,06116978 0,06122301 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,06116978 0,06119638 ! protein localization in organelle GO:0033365 161 100 0,000 0,06116978 0,06116978