pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-b2/out-0.05-06-0.01-300-run-b2//th1-pval-1e-01-06-th2-pval-1e-02-02-th3-pval-1e-01-01-run-b2/go_data/64837-8-real-Schmidt-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! polyol catabolic process GO:0046174 7 5 2,000 4,085E-09 9,394E-06 GO:0019405|alditol catabolic process, ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 3,000 6,293E-08 7,237E-05 ! cellular carbohydrate catabolic process GO:0044275 13 11 2,000 6,72E-08 5,152E-05 ! fructose metabolic process GO:0006000 20 16 2,000 2,275E-07 1,308E-04 ! alditol metabolic process GO:0019400 24 20 2,000 4,624E-07 2,127E-04 ! sperm motility GO:0030317 27 24 2,000 8,193E-07 3,141E-04 ! hexose biosynthetic process GO:0019319 35 29 2,000 1,476E-06 4,849E-04 ! monosaccharide biosynthetic process GO:0046364 38 32 2,000 2E-06 5,751E-04 ! polyol metabolic process GO:0019751 44 34 2,000 2,411E-06 6,161E-04 ! alcohol biosynthetic process GO:0046165 45 38 2,000 3,392E-06 7,803E-04 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 2,000 4,951E-06 1,035E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 1,248E-05 2,392E-03 ! carbohydrate biosynthetic process GO:0016051 97 77 2,000 2,888E-05 5,109E-03 ! alcohol catabolic process GO:0046164 104 80 2,000 3,239E-05 5,321E-03 ! interphase of mitotic cell cycle GO:0051329 156 86 2,000 4,023E-05 6,169E-03 ! interphase GO:0051325 159 88 2,000 4,31E-05 6,195E-03 ! carbohydrate catabolic process GO:0016052 121 93 2,000 5,085E-05 6,879E-03 ! cellular response to unfolded protein GO:0034620 19 16 1,000 7,101E-05 9,073E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 1,24E-04 0,01500827 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 1,492E-04 0,01716161 ! fat cell differentiation GO:0045444 37 24 1,000 1,627E-04 0,01782209 ! response to calcium ion GO:0051592 58 40 1,000 4,565E-04 0,04772667 ! positive regulation of cell cycle GO:0045787 77 45 1,000 5,781E-04 0,05781002 ! response to UV GO:0009411 75 46 1,000 6,041E-04 0,05789301 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 1,000 1,061E-03 0,09759515 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 1,000 1,096E-03 0,0969252 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 1,000 1,167E-03 0,09941411 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 1,000 1,204E-03 0,09886167 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 1,000 1,204E-03 0,09545265 ! positive regulation of ligase activity GO:0051351 99 69 1,000 1,355E-03 0,10388071 ! response to metal ion GO:0010038 103 70 1,000 1,394E-03 0,10343917 ! positive regulation of phosphorylation GO:0042327 102 70 1,000 1,394E-03 0,10020669 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 1,000 1,434E-03 0,09994094 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 1,000 1,474E-03 0,09972735 GO:0045937|positive regulation of phosphate metabolic process, ! response to inorganic substance GO:0010035 115 75 1,000 1,598E-03 0,10503439 ! regulation of ligase activity GO:0051340 114 75 1,000 1,598E-03 0,10211676 ! response to unfolded protein GO:0006986 99 76 1,000 1,641E-03 0,10199552 ! positive regulation of protein modification process GO:0031401 107 78 1,000 1,727E-03 0,10454723 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 1,000 1,816E-03 0,10709424 GO:0010498|proteasomal protein catabolic process, ! response to protein stimulus GO:0051789 111 81 1,000 1,861E-03 0,10701141 ! cell cycle arrest GO:0007050 150 86 1,000 2,095E-03 0,11750483 ! response to light stimulus GO:0009416 153 96 1,000 2,601E-03 0,14245651 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 3,998E-03 0,21385545 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 3,998E-03 0,2089951 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 3,998E-03 0,20435077 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 3,998E-03 0,19990836 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 3,998E-03 0,19565499 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 3,998E-03 0,19157884 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 3,998E-03 0,18766907 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 3,998E-03 0,18391569 ! sleep GO:0030431 11 5 0,000 3,998E-03 0,1803095 ! negative regulation of bone resorption GO:0045779 10 5 0,000 3,998E-03 0,17684201 ! nucleotide-sugar transport GO:0015780 8 5 0,000 3,998E-03 0,17350537 ! regulation of interferon-beta production GO:0032648 5 5 0,000 3,998E-03 0,17029231 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 3,998E-03 0,16719608 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 3,998E-03 0,16421044 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 3,998E-03 0,16132955 ! tongue development GO:0043586 6 5 0,000 3,998E-03 0,15854801 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 3,998E-03 0,15586075 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 3,998E-03 0,15326307 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 3,998E-03 0,15075057 ! cobalt ion transport GO:0006824 9 5 0,000 3,998E-03 0,1483191 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 3,998E-03 0,14596483 ! SMAD protein complex assembly GO:0007183 9 5 0,000 3,998E-03 0,14368413 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 3,998E-03 0,14147361 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 3,998E-03 0,13933007 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 3,998E-03 0,13725051 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 3,998E-03 0,13523212 ! embryonic camera-type eye development GO:0031076 8 5 0,000 3,998E-03 0,13327224 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 3,998E-03 0,13136835 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 3,998E-03 0,12951809 ! adaptation of signaling pathway GO:0022401 7 5 0,000 3,998E-03 0,12771923 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 3,998E-03 0,12596965 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 3,998E-03 0,12426736 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 3,998E-03 0,12261046 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 3,998E-03 0,12099716 ! positive regulation of histone modification GO:0031058 5 5 0,000 3,998E-03 0,11942577 ! malate metabolic process GO:0006108 7 5 0,000 3,998E-03 0,11789467 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 3,998E-03 0,11640234 ! behavioral response to pain GO:0048266 7 5 0,000 3,998E-03 0,11494731 ! clathrin coat assembly GO:0048268 11 5 0,000 3,998E-03 0,1135282 ! phototransduction, visible light GO:0007603 6 5 0,000 3,998E-03 0,11214371 ! regulation of dopamine uptake GO:0051584 9 5 0,000 3,998E-03 0,11079258 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 3,998E-03 0,10947362 ! mating behavior GO:0007617 6 5 0,000 3,998E-03 0,1081857 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 3,998E-03 0,10692773 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 3,998E-03 0,10569867 ! rhythmic behavior GO:0007622 12 5 0,000 3,998E-03 0,10449755 ! copulation GO:0007620 7 5 0,000 3,998E-03 0,10332342 ! glial cell fate commitment GO:0021781 12 5 0,000 3,998E-03 0,10217538 ! protein maturation by protein folding GO:0022417 12 5 0,000 3,998E-03 0,10105258 ! embryonic hemopoiesis GO:0035162 10 5 0,000 3,998E-03 0,09995418 ! regulation of potassium ion transport GO:0043266 9 5 0,000 3,998E-03 0,0988794 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 3,998E-03 0,09782749 ! apoptotic cell clearance GO:0043277 13 5 0,000 3,998E-03 0,09679773 ! lipoprotein particle clearance GO:0034381 9 5 0,000 3,998E-03 0,09578942 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 3,998E-03 0,0948019 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 3,998E-03 0,09383454 ! response to protozoan GO:0001562 9 5 0,000 3,998E-03 0,09288671 ! positive regulation of glycolysis GO:0045821 11 5 0,000 3,998E-03 0,09195784 ! lymph vessel development GO:0001945 7 5 0,000 3,998E-03 0,09104737 ! endochondral ossification GO:0001958 12 5 0,000 3,998E-03 0,09015475 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 3,998E-03 0,08927946 ! parathyroid gland development GO:0060017 8 5 0,000 3,998E-03 0,088421 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 3,998E-03 0,0875789 ! anagen GO:0042640 6 5 0,000 3,998E-03 0,08675268 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 3,998E-03 0,08594191 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 3,998E-03 0,08514615 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 3,998E-03 0,084365 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 3,998E-03 0,08359804 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 3,998E-03 0,08284491 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 3,998E-03 0,08210522 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 3,998E-03 0,08137862 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 3,998E-03 0,08066478 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 3,998E-03 0,07996334 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 3,998E-03 0,079274 ! cardiac muscle fiber development GO:0048739 7 5 0,000 3,998E-03 0,07859645 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 3,998E-03 0,07793038 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 3,998E-03 0,0772755 ! neutrophil mediated immunity GO:0002446 6 5 0,000 3,998E-03 0,07663154 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 3,998E-03 0,07599822 ! ovulation GO:0030728 6 5 0,000 3,998E-03 0,07537528 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 3,998E-03 0,07476248 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 3,998E-03 0,07415955 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 3,998E-03 0,07356628 ! response to pH GO:0009268 9 5 0,000 3,998E-03 0,07298242 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 3,998E-03 0,07240775 ! proline biosynthetic process GO:0006561 6 5 0,000 3,998E-03 0,07184207 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 3,998E-03 0,07128515 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 3,998E-03 0,0707368 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 3,998E-03 0,07019683 ! polyol biosynthetic process GO:0046173 5 5 0,000 3,998E-03 0,06966503 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 3,998E-03 0,06914124 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 3,998E-03 0,06862526 ! sister chromatid cohesion GO:0007062 9 5 0,000 3,998E-03 0,06811692 ! nerve growth factor processing GO:0032455 7 5 0,000 3,998E-03 0,06761606 ! urea metabolic process GO:0019627 6 5 0,000 3,998E-03 0,06712251 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 3,998E-03 0,06663612 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 3,998E-03 0,06615672 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 3,998E-03 0,06568417 ! neutrophil activation GO:0042119 5 5 0,000 3,998E-03 0,06521833 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 3,998E-03 0,06475905 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 3,998E-03 0,06430619 ! response to food GO:0032094 5 5 0,000 3,998E-03 0,06385961 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 3,998E-03 0,0634192 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 3,998E-03 0,06298483 ! paraxial mesoderm development GO:0048339 9 5 0,000 3,998E-03 0,06255636 ! forebrain neuron development GO:0021884 7 5 0,000 3,998E-03 0,06213368 ! melanosome organization GO:0032438 7 5 0,000 3,998E-03 0,06171667 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 3,998E-03 0,06130523 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 3,998E-03 0,06089923 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 3,998E-03 0,06049858 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 3,998E-03 0,06010317 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 3,998E-03 0,05971289 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 3,998E-03 0,05932764 ! nucleoside transport GO:0015858 6 5 0,000 3,998E-03 0,05894734 ! nucleoside salvage GO:0043174 7 5 0,000 3,998E-03 0,05857188 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 3,998E-03 0,05820117 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 3,998E-03 0,05783512 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 3,998E-03 0,05747365 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 3,998E-03 0,05711667 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 3,998E-03 0,0567641 ! early endosome to late endosome transport GO:0045022 11 5 0,000 3,998E-03 0,05641586 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 3,998E-03 0,05607186 ! depyrimidination GO:0045008 8 5 0,000 3,998E-03 0,05573203 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 3,998E-03 0,05539629 ! 5S class rRNA transcription GO:0042791 8 5 0,000 3,998E-03 0,05506458 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 3,998E-03 0,05473681 ! regulation of centrosome cycle GO:0046605 7 5 0,000 3,998E-03 0,05441293 ! neuronal ion channel clustering GO:0045161 7 5 0,000 3,998E-03 0,05409285 ! sodium ion homeostasis GO:0055078 6 5 0,000 3,998E-03 0,05377652 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 3,998E-03 0,05346386 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 3,998E-03 0,05315482 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 3,998E-03 0,05284934 ! monocyte differentiation GO:0030224 8 5 0,000 3,998E-03 0,05254734 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 3,998E-03 0,05224878 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 3,998E-03 0,05195358 ! centrosome duplication GO:0051298 5 5 0,000 3,998E-03 0,05166171 ! response to UV-C GO:0010225 6 5 0,000 3,998E-03 0,0513731 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 3,998E-03 0,05108769 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 3,998E-03 0,05080544 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 3,998E-03 0,05052629 ! regulation of dendrite development GO:0050773 12 5 0,000 3,998E-03 0,05025019 ! peptidyl-arginine modification GO:0018195 7 5 0,000 3,998E-03 0,04997709 ! positive regulation of organ growth GO:0046622 6 5 0,000 3,998E-03 0,04970694 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 3,998E-03 0,0494397 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 3,998E-03 0,04917532 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 3,998E-03 0,04891375 ! regulation of dopamine secretion GO:0014059 12 5 0,000 3,998E-03 0,04865494 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 3,998E-03 0,04839887 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 3,998E-03 0,04814547 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 3,998E-03 0,04789471 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 3,998E-03 0,04764655 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 3,998E-03 0,04740095 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 3,998E-03 0,04715787 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 3,998E-03 0,04691727 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 3,998E-03 0,04667911 ! neural tube patterning GO:0021532 6 5 0,000 3,998E-03 0,04644336 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 3,998E-03 0,04620997 ! histone demethylation GO:0016577 9 5 0,000 3,998E-03 0,04597892 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 3,998E-03 0,04575017 ! regulation of sterol transport GO:0032371 7 5 0,000 3,998E-03 0,04552369 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 3,998E-03 0,04529943 ! enteric nervous system development GO:0048484 8 5 0,000 3,998E-03 0,04507737 ! establishment of planar polarity GO:0001736 6 5 0,000 3,998E-03 0,04485749 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 3,998E-03 0,04463973 ! muscle cell proliferation GO:0033002 8 5 0,000 3,998E-03 0,04442408 ! transcription termination GO:0006353 8 5 0,000 3,998E-03 0,0442105 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 3,998E-03 0,04399897 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 3,998E-03 0,04378945 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 3,998E-03 0,04358192 ! regulation of respiratory burst GO:0060263 8 5 0,000 3,998E-03 0,04337634 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 3,998E-03 0,0431727 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 3,998E-03 0,04297096 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 3,998E-03 0,04277109 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 3,998E-03 0,04257308 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 3,998E-03 0,04237689 ! apical protein localization GO:0045176 6 5 0,000 3,998E-03 0,0421825 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 3,998E-03 0,04198988 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 3,998E-03 0,04179902 ! galactolipid metabolic process GO:0019374 7 5 0,000 3,998E-03 0,04160988 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 3,998E-03 0,04142245 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 3,998E-03 0,0412367 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 3,998E-03 0,04105261 ! triglyceride catabolic process GO:0019433 6 5 0,000 3,998E-03 0,04087015 ! glial cell migration GO:0008347 10 5 0,000 3,998E-03 0,04068931 ! determination of adult lifespan GO:0008340 8 5 0,000 3,998E-03 0,04051006 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 3,998E-03 0,04033239 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 3,998E-03 0,04015626 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 3,998E-03 0,03998167 ! somatic stem cell maintenance GO:0035019 13 5 0,000 3,998E-03 0,03980859 ! cerebellar cortex formation GO:0021697 6 5 0,000 3,998E-03 0,039637 ! neural plate development GO:0001840 6 5 0,000 3,998E-03 0,03946689 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 3,998E-03 0,03929822 ! regulation of sensory perception GO:0051931 6 5 0,000 3,998E-03 0,039131 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 3,998E-03 0,03896519 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 3,998E-03 0,03880078 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 3,998E-03 0,03863775 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 3,998E-03 0,03847609 ! sensory cilium assembly GO:0035058 6 5 0,000 3,998E-03 0,03831577 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 3,998E-03 0,03815678 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 3,998E-03 0,03799911 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 3,998E-03 0,03784273 ! spindle assembly GO:0051225 5 5 0,000 3,998E-03 0,03768764 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 3,998E-03 0,03753381 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 3,998E-03 0,03738124 ! protein amino acid prenylation GO:0018346 9 5 0,000 3,998E-03 0,0372299 ! organ regeneration GO:0031100 7 5 0,000 3,998E-03 0,03707978 ! NAD biosynthetic process GO:0009435 7 5 0,000 3,998E-03 0,03693086 ! carnitine metabolic process GO:0009437 5 5 0,000 3,998E-03 0,03678314 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 3,998E-03 0,03663659 ! cellular anion homeostasis GO:0030002 6 5 0,000 3,998E-03 0,03649121 GO:0055081|anion homeostasis, ! tRNA transcription GO:0009304 11 6 0,000 4,796E-03 0,04360016 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 4,796E-03 0,0434285 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 4,796E-03 0,04325819 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 4,796E-03 0,04308922 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 4,796E-03 0,04292156 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 4,796E-03 0,04275519 ! regulation of helicase activity GO:0051095 11 6 0,000 4,796E-03 0,04259011 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 4,796E-03 0,04242631 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 4,796E-03 0,04226375 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 4,796E-03 0,04210244 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 4,796E-03 0,04194236 ! positive regulation of axon extension GO:0045773 8 6 0,000 4,796E-03 0,04178348 ! prostate gland development GO:0030850 9 6 0,000 4,796E-03 0,04162581 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 4,796E-03 0,04146932 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 4,796E-03 0,04131401 ! forebrain neuron differentiation GO:0021879 9 6 0,000 4,796E-03 0,04115985 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 4,796E-03 0,04100684 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 4,796E-03 0,04085496 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 4,796E-03 0,04070421 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 4,796E-03 0,04055456 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 4,796E-03 0,04040601 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 4,796E-03 0,04025854 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 4,796E-03 0,04011214 ! neuron adhesion GO:0007158 9 6 0,000 4,796E-03 0,03996681 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 4,796E-03 0,03982253 ! establishment of tissue polarity GO:0007164 7 6 0,000 4,796E-03 0,03967928 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 4,796E-03 0,03953706 ! signal peptide processing GO:0006465 8 6 0,000 4,796E-03 0,03939586 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 4,796E-03 0,03925566 ! mRNA stabilization GO:0048255 15 6 0,000 4,796E-03 0,03911645 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 4,796E-03 0,03897823 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 4,796E-03 0,03884098 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 4,796E-03 0,0387047 ! opsonization GO:0008228 8 6 0,000 4,796E-03 0,03856937 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 4,796E-03 0,03843498 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 4,796E-03 0,03830153 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 4,796E-03 0,038169 ! protein amino acid dealkylation GO:0008214 11 6 0,000 4,796E-03 0,03803738 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 4,796E-03 0,03790667 ! photoreceptor cell development GO:0042461 10 6 0,000 4,796E-03 0,03777685 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 4,796E-03 0,03764792 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 4,796E-03 0,03751986 ! mechanosensory behavior GO:0007638 8 6 0,000 4,796E-03 0,03739268 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 4,796E-03 0,03726635 ! negative regulation of endocytosis GO:0045806 8 6 0,000 4,796E-03 0,03714087 ! response to interferon-gamma GO:0034341 12 6 0,000 4,796E-03 0,03701624 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 4,796E-03 0,03689244 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 4,796E-03 0,03676947 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 4,796E-03 0,03664731 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 4,796E-03 0,03652596 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 4,796E-03 0,03640541 ! cGMP-mediated signaling GO:0019934 10 6 0,000 4,796E-03 0,03628566 ! activation of MAPKKK activity GO:0000185 10 6 0,000 4,796E-03 0,03616669 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 4,796E-03 0,0360485 ! thymic T cell selection GO:0045061 12 6 0,000 4,796E-03 0,03593107 ! protein lipoylation GO:0009249 10 6 0,000 4,796E-03 0,03581441 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 4,796E-03 0,03569851 ! pigment granule organization GO:0048753 11 6 0,000 4,796E-03 0,03558335 ! drug transport GO:0015893 6 6 0,000 4,796E-03 0,03546894 ! cysteine metabolic process GO:0006534 7 6 0,000 4,796E-03 0,03535526 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 4,796E-03 0,0352423 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 4,796E-03 0,03513006 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 4,796E-03 0,03501854 ! histidine metabolic process GO:0006547 6 6 0,000 4,796E-03 0,03490772 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 4,796E-03 0,0347976 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 4,796E-03 0,03468817 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 4,796E-03 0,03457943 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 4,796E-03 0,03447137 ! adenohypophysis development GO:0021984 10 6 0,000 4,796E-03 0,03436399 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 4,796E-03 0,03425727 ! hyperosmotic response GO:0006972 8 6 0,000 4,796E-03 0,03415121 ! microtubule nucleation GO:0007020 10 6 0,000 4,796E-03 0,0340458 ! ER overload response GO:0006983 7 6 0,000 4,796E-03 0,03394105 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 4,796E-03 0,03383693 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 4,796E-03 0,03373345 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 4,796E-03 0,03363061 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 4,796E-03 0,03352839 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 4,796E-03 0,03342679 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 4,796E-03 0,0333258 ! response to dietary excess GO:0002021 7 6 0,000 4,796E-03 0,03322542 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 4,796E-03 0,03312564 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 4,796E-03 0,03302647 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 4,796E-03 0,03292788 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 4,796E-03 0,03282988 ! glycerol ether catabolic process GO:0044269 8 6 0,000 4,796E-03 0,03273246 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 4,796E-03 0,03263562 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 4,796E-03 0,03253935 ! neuron apoptosis GO:0051402 8 6 0,000 4,796E-03 0,03244365 ! organic alcohol transport GO:0015850 9 6 0,000 4,796E-03 0,0323485 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 4,796E-03 0,03225392 ! T cell mediated immunity GO:0002456 12 6 0,000 4,796E-03 0,03215988 ! male sex determination GO:0030238 9 6 0,000 4,796E-03 0,03206639 ! carnitine transport GO:0015879 8 6 0,000 4,796E-03 0,03197345 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 4,796E-03 0,03188104 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 4,796E-03 0,03178916 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 4,796E-03 0,03169782 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 4,796E-03 0,03160699 ! positive regulation of exocytosis GO:0045921 6 6 0,000 4,796E-03 0,03151668 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 4,796E-03 0,03142689 ! parturition GO:0007567 12 6 0,000 4,796E-03 0,03133761 ! negative regulation of translational initiation GO:0045947 7 6 0,000 4,796E-03 0,03124884 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 4,796E-03 0,03116056 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 4,796E-03 0,03107279 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 4,796E-03 0,0309855 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 4,796E-03 0,03089871 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 4,796E-03 0,0308124 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 4,796E-03 0,03072657 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 4,796E-03 0,03064122 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 4,796E-03 0,03055634 ! macrophage differentiation GO:0030225 10 6 0,000 4,796E-03 0,03047193 ! astrocyte development GO:0014002 14 6 0,000 4,796E-03 0,03038799 ! hyaluronan metabolic process GO:0030212 6 6 0,000 4,796E-03 0,0303045 ! purine base biosynthetic process GO:0009113 14 6 0,000 4,796E-03 0,03022148 ! interaction with symbiont GO:0051702 8 6 0,000 4,796E-03 0,03013891 ! anterograde axon cargo transport GO:0008089 8 6 0,000 4,796E-03 0,03005678 ! skeletal muscle contraction GO:0003009 6 6 0,000 4,796E-03 0,02997511 ! eating behavior GO:0042755 6 6 0,000 4,796E-03 0,02989387 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 4,796E-03 0,02981308 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 4,796E-03 0,02973272 ! response to copper ion GO:0046688 9 6 0,000 4,796E-03 0,02965279 ! DNA topological change GO:0006265 8 6 0,000 4,796E-03 0,0295733 ! response to exogenous dsRNA GO:0043330 8 6 0,000 4,796E-03 0,02949422 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 4,796E-03 0,02941557 ! establishment of melanosome localization GO:0032401 9 6 0,000 4,796E-03 0,02933734 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 4,796E-03 0,02925952 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 4,796E-03 0,02918212 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 4,796E-03 0,02910512 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 4,796E-03 0,02902853 ! nucleoside catabolic process GO:0009164 6 6 0,000 4,796E-03 0,02895234 ! gas homeostasis GO:0033483 11 6 0,000 4,796E-03 0,02887654 ! hair follicle maturation GO:0048820 7 6 0,000 4,796E-03 0,02880115 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 4,796E-03 0,02872614 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 4,796E-03 0,02865153 ! Schwann cell development GO:0014044 14 6 0,000 4,796E-03 0,0285773 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 4,796E-03 0,02850346 ! dendrite morphogenesis GO:0048813 9 6 0,000 4,796E-03 0,02843 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 4,796E-03 0,02835691 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 4,796E-03 0,0282842 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 4,796E-03 0,02821187 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 4,796E-03 0,0281399 ! histone ubiquitination GO:0016574 7 6 0,000 4,796E-03 0,02806829 ! regulation of meiosis GO:0040020 10 6 0,000 4,796E-03 0,02799705 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 4,796E-03 0,02792618 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 4,796E-03 0,02785566 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 4,796E-03 0,02778549 ! regulation of mast cell activation GO:0033003 6 6 0,000 4,796E-03 0,02771568 ! membrane to membrane docking GO:0022614 12 6 0,000 4,796E-03 0,02764621 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 4,796E-03 0,0275771 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 4,796E-03 0,02750833 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 4,796E-03 0,0274399 ! receptor internalization GO:0031623 9 6 0,000 4,796E-03 0,02737181 ! neutrophil homeostasis GO:0001780 6 6 0,000 4,796E-03 0,02730406 ! coenzyme A metabolic process GO:0015936 9 6 0,000 4,796E-03 0,02723664 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 4,796E-03 0,02716956 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 4,796E-03 0,0271028 ! protein deubiquitination GO:0016579 8 6 0,000 4,796E-03 0,02703637 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 4,796E-03 0,02697027 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 4,796E-03 0,02690449 ! peptidyl-histidine modification GO:0018202 9 6 0,000 4,796E-03 0,02683903 ! axonal fasciculation GO:0007413 9 6 0,000 4,796E-03 0,02677388 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 4,796E-03 0,02670905 ! thiamin metabolic process GO:0006772 6 6 0,000 4,796E-03 0,02664454 ! midbrain development GO:0030901 6 6 0,000 4,796E-03 0,02658034 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 4,796E-03 0,02651644 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 4,796E-03 0,02645285 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 4,796E-03 0,02638957 ! progesterone metabolic process GO:0042448 8 6 0,000 4,796E-03 0,02632659 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 4,796E-03 0,0262639 ! glycolipid catabolic process GO:0019377 13 6 0,000 4,796E-03 0,02620152 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 4,796E-03 0,02613943 ! positive regulation of glucose import GO:0046326 6 6 0,000 4,796E-03 0,02607764 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 4,796E-03 0,02601613 ! adult feeding behavior GO:0008343 6 6 0,000 4,796E-03 0,02595492 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 4,796E-03 0,02589399 ! blastocyst growth GO:0001832 15 6 0,000 4,796E-03 0,02583335 ! pigment granule transport GO:0051904 12 6 0,000 4,796E-03 0,02577299 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 4,796E-03 0,02571291 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 4,796E-03 0,02565312 ! catecholamine transport GO:0051937 7 6 0,000 4,796E-03 0,0255936 ! organ or tissue specific immune response GO:0002251 7 6 0,000 4,796E-03 0,02553435 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 4,796E-03 0,02547538 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 4,796E-03 0,02541668 ! negative regulation of B cell activation GO:0050869 9 6 0,000 4,796E-03 0,02535825 ! protein prenylation GO:0018342 10 6 0,000 4,796E-03 0,02530009 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 4,796E-03 0,0252422 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 4,796E-03 0,02518457 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 4,796E-03 0,0251272 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 4,796E-03 0,02507009 ! positive regulation of coagulation GO:0050820 11 6 0,000 4,796E-03 0,02501324 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 5,593E-03 0,02910527 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 5,593E-03 0,02903957 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 5,593E-03 0,02897417 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 5,593E-03 0,02890906 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 5,593E-03 0,02884424 ! synaptonemal complex assembly GO:0007130 10 7 0,000 5,593E-03 0,02877971 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 5,593E-03 0,02871547 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 5,593E-03 0,02865151 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 5,593E-03 0,02858784 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 5,593E-03 0,02852446 ! reproductive behavior GO:0019098 12 7 0,000 5,593E-03 0,02846135 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 5,593E-03 0,02839852 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 5,593E-03 0,02833597 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 5,593E-03 0,02827369 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 5,593E-03 0,02821169 ! oligopeptide transport GO:0006857 11 7 0,000 5,593E-03 0,02814996 ! protein amino acid sulfation GO:0006477 9 7 0,000 5,593E-03 0,02808849 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 5,593E-03 0,0280273 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 5,593E-03 0,02796637 ! RNA methylation GO:0001510 11 7 0,000 5,593E-03 0,0279057 ! pericardium development GO:0060039 8 7 0,000 5,593E-03 0,0278453 ! macrophage chemotaxis GO:0048246 10 7 0,000 5,593E-03 0,02778516 ! fibril organization GO:0043206 13 7 0,000 5,593E-03 0,02772528 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 5,593E-03 0,02766566 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 5,593E-03 0,02760629 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 5,593E-03 0,02754717 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 5,593E-03 0,02748831 ! lipoprotein transport GO:0042953 9 7 0,000 5,593E-03 0,0274297 ! cerebral cortex cell migration GO:0021795 11 7 0,000 5,593E-03 0,02737134 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 5,593E-03 0,02731323 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 5,593E-03 0,02725536 ! estrogen metabolic process GO:0008210 14 7 0,000 5,593E-03 0,02719774 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 5,593E-03 0,02714036 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 5,593E-03 0,02708322 ! chemosensory behavior GO:0007635 9 7 0,000 5,593E-03 0,02702632 ! microtubule bundle formation GO:0001578 8 7 0,000 5,593E-03 0,02696966 ! T-helper 1 type immune response GO:0042088 11 7 0,000 5,593E-03 0,02691324 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 5,593E-03 0,02685706 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 5,593E-03 0,0268011 ! leukocyte degranulation GO:0043299 10 7 0,000 5,593E-03 0,02674538 ! bile acid and bile salt transport GO:0015721 9 7 0,000 5,593E-03 0,0266899 ! reflex GO:0060004 12 7 0,000 5,593E-03 0,02663464 ! positive regulation of isotype switching GO:0045830 15 7 0,000 5,593E-03 0,02657961 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 5,593E-03 0,0265248 ! protein-cofactor linkage GO:0018065 13 7 0,000 5,593E-03 0,02647023 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 5,593E-03 0,02641587 ! glycerolipid catabolic process GO:0046503 9 7 0,000 5,593E-03 0,02636174 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 5,593E-03 0,02630783 ! spinal cord patterning GO:0021511 7 7 0,000 5,593E-03 0,02625414 ! hemoglobin metabolic process GO:0020027 10 7 0,000 5,593E-03 0,02620067 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 5,593E-03 0,02614742 ! adrenal gland development GO:0030325 17 7 0,000 5,593E-03 0,02609438 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 5,593E-03 0,02604156 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 5,593E-03 0,02598895 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 5,593E-03 0,02593655 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 5,593E-03 0,02588437 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 5,593E-03 0,02583239 ! endosome organization GO:0007032 10 7 0,000 5,593E-03 0,02578062 ! thyroid hormone generation GO:0006590 11 7 0,000 5,593E-03 0,02572906 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 5,593E-03 0,0256777 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 5,593E-03 0,02562655 ! regulation of pigmentation during development GO:0048070 15 7 0,000 5,593E-03 0,02557561 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 5,593E-03 0,02552486 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 5,593E-03 0,02547432 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 5,593E-03 0,02542397 ! galactose metabolic process GO:0006012 10 7 0,000 5,593E-03 0,02537383 ! vesicle fusion GO:0006906 15 7 0,000 5,593E-03 0,02532388 ! intracellular pH reduction GO:0051452 10 7 0,000 5,593E-03 0,02527413 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 5,593E-03 0,02522457 ! organ growth GO:0035265 11 7 0,000 5,593E-03 0,0251752 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 5,593E-03 0,02512603 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 5,593E-03 0,02507706 ! Rac protein signal transduction GO:0016601 7 7 0,000 5,593E-03 0,02502827 ! retinol metabolic process GO:0042572 9 7 0,000 5,593E-03 0,02497967 ! behavioral fear response GO:0001662 13 7 0,000 5,593E-03 0,02493126 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 5,593E-03 0,02488304 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 5,593E-03 0,024835 ! rRNA modification GO:0000154 12 7 0,000 5,593E-03 0,02478715 ! protein heterooligomerization GO:0051291 10 7 0,000 5,593E-03 0,02473948 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 5,593E-03 0,024692 ! response to UV-B GO:0010224 11 7 0,000 5,593E-03 0,02464469 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 5,593E-03 0,02459757 ! protein retention in ER lumen GO:0006621 12 7 0,000 5,593E-03 0,02455063 ! intermediate filament organization GO:0045109 11 7 0,000 5,593E-03 0,02450387 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 5,593E-03 0,02445728 ! cardiac muscle cell development GO:0055013 9 7 0,000 5,593E-03 0,02441087 ! fibrinolysis GO:0042730 9 7 0,000 5,593E-03 0,02436464 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 5,593E-03 0,02431858 ! regulation of circadian rhythm GO:0042752 11 7 0,000 5,593E-03 0,0242727 ! B cell lineage commitment GO:0002326 17 7 0,000 5,593E-03 0,02422699 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 5,593E-03 0,02418145 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 5,593E-03 0,02413608 ! response to tropane GO:0014073 13 7 0,000 5,593E-03 0,02409088 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 5,593E-03 0,02404585 ! melanosome localization GO:0032400 10 7 0,000 5,593E-03 0,02400099 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 5,593E-03 0,02395629 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 5,593E-03 0,02391177 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 5,593E-03 0,0238674 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 5,593E-03 0,0238232 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 5,593E-03 0,02377917 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 5,593E-03 0,02373529 ! mast cell activation GO:0045576 9 7 0,000 5,593E-03 0,02369158 ! multicellular organismal aging GO:0010259 11 7 0,000 5,593E-03 0,02364803 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 5,593E-03 0,02360464 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 5,593E-03 0,02356141 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 5,593E-03 0,02351834 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 5,593E-03 0,02347542 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 5,593E-03 0,02343266 ! establishment of nucleus localization GO:0040023 13 7 0,000 5,593E-03 0,02339005 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 5,593E-03 0,0233476 ! T cell lineage commitment GO:0002360 12 7 0,000 5,593E-03 0,02330531 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 5,593E-03 0,02326316 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 5,593E-03 0,02322117 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 5,593E-03 0,02317933 ! regulation of lipid transport GO:0032368 13 7 0,000 5,593E-03 0,02313764 ! response to tumor cell GO:0002347 12 7 0,000 5,593E-03 0,0230961 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 5,593E-03 0,02305471 ! neuroblast proliferation GO:0007405 13 7 0,000 5,593E-03 0,02301347 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 5,593E-03 0,02297237 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 5,593E-03 0,02293143 ! peptidyl-threonine modification GO:0018210 18 7 0,000 5,593E-03 0,02289062 ! diuresis GO:0030146 12 7 0,000 5,593E-03 0,02284996 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 5,593E-03 0,02280945 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 5,593E-03 0,02276908 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 5,593E-03 0,02272885 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 5,593E-03 0,02268876 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 5,593E-03 0,02264882 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 5,593E-03 0,02260902 ! melanin biosynthetic process GO:0042438 8 7 0,000 5,593E-03 0,02256935 ! regulation of synaptogenesis GO:0051963 10 7 0,000 5,593E-03 0,02252982 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 5,593E-03 0,02249044 ! dopamine biosynthetic process GO:0042416 15 7 0,000 5,593E-03 0,02245119 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 5,593E-03 0,02241207 ! lymph node development GO:0048535 9 7 0,000 5,593E-03 0,0223731 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 5,593E-03 0,02233425 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 5,593E-03 0,02229555 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 5,593E-03 0,02225697 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 5,593E-03 0,02221853 ! endosome to lysosome transport GO:0008333 10 7 0,000 5,593E-03 0,02218022 ! ATP catabolic process GO:0006200 10 7 0,000 5,593E-03 0,02214205 ! establishment of pigment granule localization GO:0051905 13 7 0,000 5,593E-03 0,022104 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 5,593E-03 0,02206609 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 5,593E-03 0,0220283 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 5,593E-03 0,02199065 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 5,593E-03 0,02195312 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 5,593E-03 0,02191572 ! muscle adaptation GO:0043500 12 7 0,000 5,593E-03 0,02187845 ! amino sugar catabolic process GO:0046348 9 7 0,000 5,593E-03 0,02184131 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 5,593E-03 0,02180429 ! retina homeostasis GO:0001895 9 7 0,000 5,593E-03 0,02176739 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 5,593E-03 0,02173062 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 5,593E-03 0,02169398 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 5,593E-03 0,02165746 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 5,593E-03 0,02162106 ! behavioral response to nicotine GO:0035095 11 7 0,000 5,593E-03 0,02158478 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 5,593E-03 0,02154863 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 5,593E-03 0,02151259 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 6,39E-03 0,02453565 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 6,39E-03 0,02449476 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 6,39E-03 0,024454 ! axon extension GO:0048675 11 8 0,000 6,39E-03 0,02441338 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 6,39E-03 0,0243729 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 6,39E-03 0,02433254 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 6,39E-03 0,02429232 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 6,39E-03 0,02425224 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 6,39E-03 0,02421228 ! cell proliferation in forebrain GO:0021846 10 8 0,000 6,39E-03 0,02417246 ! positive regulation of B cell proliferation GO:0030890 11 8 0,000 6,39E-03 0,02413277 ! phosphate transport GO:0006817 10 8 0,000 6,39E-03 0,02409321 ! N-glycan processing GO:0006491 12 8 0,000 6,39E-03 0,02405377 ! Golgi to endosome transport GO:0006895 16 8 0,000 6,39E-03 0,02401447 ! UTP metabolic process GO:0046051 8 8 0,000 6,39E-03 0,02397529 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 6,39E-03 0,02393625 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 6,39E-03 0,02389733 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 6,39E-03 0,02385853 ! neurotransmitter uptake GO:0001504 10 8 0,000 6,39E-03 0,02381986 ! succinate metabolic process GO:0006105 14 8 0,000 6,39E-03 0,02378132 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 6,39E-03 0,0237429 ! smoothened signaling pathway GO:0007224 8 8 0,000 6,39E-03 0,02370461 ! membrane hyperpolarization GO:0060081 10 8 0,000 6,39E-03 0,02366643 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 6,39E-03 0,02362839 ! keratinocyte proliferation GO:0043616 12 8 0,000 6,39E-03 0,02359046 ! middle ear morphogenesis GO:0042474 9 8 0,000 6,39E-03 0,02355265 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 6,39E-03 0,02351497 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 6,39E-03 0,02347741 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 6,39E-03 0,02343996 ! ganglioside metabolic process GO:0001573 15 8 0,000 6,39E-03 0,02340264 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 6,39E-03 0,02336543 ! pseudouridine synthesis GO:0001522 9 8 0,000 6,39E-03 0,02332834 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 6,39E-03 0,02329137 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 6,39E-03 0,02325452 ! endothelial cell differentiation GO:0045446 14 8 0,000 6,39E-03 0,02321778 ! ceramide biosynthetic process GO:0046513 9 8 0,000 6,39E-03 0,02318116 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 6,39E-03 0,02314465 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 0,000 6,39E-03 0,02310826 ! astrocyte differentiation GO:0048708 16 8 0,000 6,39E-03 0,02307199 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 6,39E-03 0,02303582 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 6,39E-03 0,02299977 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 6,39E-03 0,02296384 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 6,39E-03 0,02292801 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 6,39E-03 0,0228923 ! melanin metabolic process GO:0006582 12 8 0,000 6,39E-03 0,0228567 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 6,39E-03 0,0228212 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 6,39E-03 0,02278582 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 6,39E-03 0,02275055 ! macrophage activation GO:0042116 12 8 0,000 6,39E-03 0,02271539 ! regulation of type I interferon production GO:0032479 8 8 0,000 6,39E-03 0,02268033 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 6,39E-03 0,02264539 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 6,39E-03 0,02261055 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 6,39E-03 0,02257582 ! regulation of vascular permeability GO:0043114 12 8 0,000 6,39E-03 0,02254119 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 6,39E-03 0,02250667 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 6,39E-03 0,02247226 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 6,39E-03 0,02243795 ! ruffle organization GO:0031529 11 8 0,000 6,39E-03 0,02240374 ! osteoblast development GO:0002076 13 8 0,000 6,39E-03 0,02236964 ! lens development in camera-type eye GO:0002088 10 8 0,000 6,39E-03 0,02233565 ! positive regulation of vasodilation GO:0045909 12 8 0,000 6,39E-03 0,02230175 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 6,39E-03 0,02226796 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 6,39E-03 0,02223427 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 6,39E-03 0,02220069 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 6,39E-03 0,0221672 ! Schwann cell differentiation GO:0014037 17 8 0,000 6,39E-03 0,02213382 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 6,39E-03 0,02210053 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 6,39E-03 0,02206735 ! regulation of gliogenesis GO:0014013 20 8 0,000 6,39E-03 0,02203427 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 6,39E-03 0,02200128 ! oligodendrocyte development GO:0014003 8 8 0,000 6,39E-03 0,02196839 ! segment specification GO:0007379 10 8 0,000 6,39E-03 0,02193561 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 6,39E-03 0,02190291 ! cellular extravasation GO:0045123 11 8 0,000 6,39E-03 0,02187032 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 6,39E-03 0,02183782 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 6,39E-03 0,02180542 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 6,39E-03 0,02177312 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 6,39E-03 0,02174091 ! snRNA metabolic process GO:0016073 10 8 0,000 6,39E-03 0,0217088 GO:0016180|snRNA processing, ! phosphoinositide 3-kinase cascade GO:0014065 23 8 0,000 6,39E-03 0,02167678 ! regulation of interleukin-4 production GO:0032673 16 8 0,000 6,39E-03 0,02164485 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 6,39E-03 0,02161302 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 6,39E-03 0,02158129 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 6,39E-03 0,02154964 ! nucleosome disassembly GO:0006337 12 8 0,000 6,39E-03 0,02151809 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 6,39E-03 0,02148663 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 6,39E-03 0,02145526 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 6,39E-03 0,02142399 ! icosanoid secretion GO:0032309 12 8 0,000 6,39E-03 0,0213928 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 6,39E-03 0,02136171 ! leukocyte activation during immune response GO:0002366 13 8 0,000 6,39E-03 0,0213307 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 6,39E-03 0,02129979 ! cerebellum morphogenesis GO:0021587 9 8 0,000 6,39E-03 0,02126897 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 6,39E-03 0,02123823 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 6,39E-03 0,02120758 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 6,39E-03 0,02117703 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 6,39E-03 0,02114656 ! sterol catabolic process GO:0016127 9 8 0,000 6,39E-03 0,02111617 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 6,39E-03 0,02108588 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 6,39E-03 0,02105567 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 6,39E-03 0,02102554 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 6,39E-03 0,02099551 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 6,39E-03 0,02096556 ! prophase GO:0051324 11 8 0,000 6,39E-03 0,02093569 ! S phase GO:0051320 8 8 0,000 6,39E-03 0,02090591 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 6,39E-03 0,02087622 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 6,39E-03 0,0208466 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 6,39E-03 0,02081708 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 6,39E-03 0,02078763 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 6,39E-03 0,02075827 ! hormone catabolic process GO:0042447 13 8 0,000 6,39E-03 0,02072899 ! quaternary ammonium group transport GO:0015697 10 8 0,000 6,39E-03 0,0206998 ! myeloid cell homeostasis GO:0002262 8 8 0,000 6,39E-03 0,02067068 ! regulation of fibrinolysis GO:0051917 13 8 0,000 6,39E-03 0,02064165 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 6,39E-03 0,0206127 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 6,39E-03 0,02058383 ! regulation of telomere maintenance GO:0032204 10 8 0,000 6,39E-03 0,02055504 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 6,39E-03 0,02052633 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 6,39E-03 0,02049771 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 6,39E-03 0,02046916 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 6,39E-03 0,02044069 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 6,39E-03 0,0204123 ! lamellipodium assembly GO:0030032 9 8 0,000 6,39E-03 0,02038399 ! regulation of embryonic development GO:0045995 16 8 0,000 6,39E-03 0,02035576 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 6,39E-03 0,0203276 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 6,39E-03 0,02029952 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 6,39E-03 0,02027153 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 7,186E-03 0,02276559 ! regulation of developmental growth GO:0048638 13 9 0,000 7,186E-03 0,02273428 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 7,186E-03 0,02270305 ! telencephalon cell migration GO:0022029 16 9 0,000 7,186E-03 0,0226719 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 7,186E-03 0,02264085 ! pentose-phosphate shunt GO:0006098 12 9 0,000 7,186E-03 0,02260987 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 7,186E-03 0,02257899 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 7,186E-03 0,02254818 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 7,186E-03 0,02251746 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 7,186E-03 0,02248683 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 7,186E-03 0,02245628 ! GTP metabolic process GO:0046039 9 9 0,000 7,186E-03 0,02242581 ! elastic fiber assembly GO:0048251 13 9 0,000 7,186E-03 0,02239542 ! social behavior GO:0035176 14 9 0,000 7,186E-03 0,02236511 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 7,186E-03 0,02233489 ! artery development GO:0060840 19 9 0,000 7,186E-03 0,02230475 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 7,186E-03 0,02227469 ! regulation of glycolysis GO:0006110 15 9 0,000 7,186E-03 0,02224471 ! response to pain GO:0048265 16 9 0,000 7,186E-03 0,02221481 ! protein complex disassembly GO:0043241 17 9 0,000 7,186E-03 0,02218499 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 7,186E-03 0,02215525 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 7,186E-03 0,02212559 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 7,186E-03 0,02209601 ! lung alveolus development GO:0048286 17 9 0,000 7,186E-03 0,02206651 ! ciliary or flagellar motility GO:0001539 10 9 0,000 7,186E-03 0,02203709 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 7,186E-03 0,02200775 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 7,186E-03 0,02197848 ! regulation of exit from mitosis GO:0007096 12 9 0,000 7,186E-03 0,02194929 ! ventral spinal cord development GO:0021517 11 9 0,000 7,186E-03 0,02192018 ! protein targeting to ER GO:0045047 19 9 0,000 7,186E-03 0,02189115 ! T cell selection GO:0045058 18 9 0,000 7,186E-03 0,02186219 ! endoderm development GO:0007492 12 9 0,000 7,186E-03 0,02183331 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 7,186E-03 0,02180451 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 7,186E-03 0,02177578 ! arginine catabolic process GO:0006527 10 9 0,000 7,186E-03 0,02174713 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 7,186E-03 0,02171855 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 7,186E-03 0,02169005 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 7,186E-03 0,02166162 ! phosphagen metabolic process GO:0006599 12 9 0,000 7,186E-03 0,02163327 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 7,186E-03 0,02160499 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 7,186E-03 0,02157679 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 7,186E-03 0,02154866 ! regulation of stress fiber formation GO:0051492 20 9 0,000 7,186E-03 0,0215206 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 7,186E-03 0,02149261 ! mannose metabolic process GO:0006013 9 9 0,000 7,186E-03 0,0214647 ! substrate-bound cell migration GO:0006929 10 9 0,000 7,186E-03 0,02143686 ! receptor clustering GO:0043113 15 9 0,000 7,186E-03 0,02140909 ! epithelial cell development GO:0002064 10 9 0,000 7,186E-03 0,0213814 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 7,186E-03 0,02135377 ! retinoic acid metabolic process GO:0042573 11 9 0,000 7,186E-03 0,02132622 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 7,186E-03 0,02129874 ! positive regulation of translational initiation GO:0045948 10 9 0,000 7,186E-03 0,02127132 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 7,186E-03 0,02124398 ! motor axon guidance GO:0008045 14 9 0,000 7,186E-03 0,02121671 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 7,186E-03 0,02118951 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 7,186E-03 0,02116238 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 7,186E-03 0,02113532 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 7,186E-03 0,02110833 ! blastoderm segmentation GO:0007350 11 9 0,000 7,186E-03 0,0210814 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 7,186E-03 0,02105455 ! DNA ligation GO:0006266 14 9 0,000 7,186E-03 0,02102776 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 7,186E-03 0,02100104 ! response to amine stimulus GO:0014075 13 9 0,000 7,186E-03 0,02097439 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 7,186E-03 0,02094781 ! erythrocyte development GO:0048821 11 9 0,000 7,186E-03 0,02092129 ! renal water homeostasis GO:0003091 14 9 0,000 7,186E-03 0,02089484 ! postreplication repair GO:0006301 11 9 0,000 7,186E-03 0,02086846 ! mRNA cleavage GO:0006379 13 9 0,000 7,186E-03 0,02084214 ! hindbrain morphogenesis GO:0021575 12 9 0,000 7,186E-03 0,02081589 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 7,186E-03 0,02078971 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 7,186E-03 0,02076359 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 7,186E-03 0,02073754 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 7,186E-03 0,02071155 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 7,186E-03 0,02068563 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 7,186E-03 0,02065977 ! acid secretion GO:0046717 14 9 0,000 7,186E-03 0,02063398 ! musculoskeletal movement GO:0050881 11 9 0,000 7,186E-03 0,02060825 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 7,186E-03 0,02058259 ! methionine biosynthetic process GO:0009086 10 9 0,000 7,186E-03 0,02055699 ! purine base metabolic process GO:0006144 18 9 0,000 7,186E-03 0,02053145 ! oocyte differentiation GO:0009994 12 9 0,000 7,186E-03 0,02050598 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 7,186E-03 0,02048057 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 7,186E-03 0,02045522 ! spleen development GO:0048536 15 9 0,000 7,186E-03 0,02042994 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 7,186E-03 0,02040471 ! anterior/posterior axis specification GO:0009948 11 9 0,000 7,186E-03 0,02037955 ! regulation of RNA splicing GO:0043484 14 9 0,000 7,186E-03 0,02035446 ! detection of calcium ion GO:0005513 13 9 0,000 7,186E-03 0,02032942 ! blastocyst formation GO:0001825 12 9 0,000 7,186E-03 0,02030445 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 7,186E-03 0,02027953 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 7,186E-03 0,02025468 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 7,186E-03 0,02022989 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 7,186E-03 0,02020516 ! regulation of amino acid transport GO:0051955 11 9 0,000 7,186E-03 0,02018049 ! positive regulation of amine transport GO:0051954 15 9 0,000 7,186E-03 0,02015588 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 7,186E-03 0,02013133 ! prepulse inhibition GO:0060134 14 9 0,000 7,186E-03 0,02010684 ! embryonic placenta development GO:0001892 12 9 0,000 7,186E-03 0,0200824 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 7,186E-03 0,02005803 ! insulin secretion GO:0030073 17 9 0,000 7,186E-03 0,02003372 ! sequestering of metal ion GO:0051238 11 9 0,000 7,186E-03 0,02000947 ! response to nicotine GO:0035094 16 9 0,000 7,186E-03 0,01998527 ! establishment of cell polarity GO:0030010 12 9 0,000 7,186E-03 0,01996113 ! nucleus localization GO:0051647 15 9 0,000 7,186E-03 0,01993705 ! regulation of synapse organization GO:0050807 12 9 0,000 7,186E-03 0,01991303 ! localization within membrane GO:0051668 15 9 0,000 7,186E-03 0,01988907 ! negative regulation of muscle development GO:0048635 12 10 0,000 7,981E-03 0,02206421 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 7,981E-03 0,02203772 ! neuron fate specification GO:0048665 11 10 0,000 7,981E-03 0,02201129 ! negative regulation of blood pressure GO:0045776 22 10 0,000 7,981E-03 0,02198493 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 7,981E-03 0,02195864 ! thyroid gland development GO:0030878 19 10 0,000 7,981E-03 0,0219324 ! regulation of B cell proliferation GO:0030888 15 10 0,000 7,981E-03 0,02190623 ! regulation of phosphatase activity GO:0010921 21 10 0,000 7,981E-03 0,02188012 ! synapsis GO:0007129 13 10 0,000 7,981E-03 0,02185407 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 7,981E-03 0,02182808 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 7,981E-03 0,02180216 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 7,981E-03 0,0217763 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 7,981E-03 0,0217505 ! sulfate transport GO:0008272 12 10 0,000 7,981E-03 0,02172476 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 7,981E-03 0,02169908 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 7,981E-03 0,02167346 ! androgen metabolic process GO:0008209 13 10 0,000 7,981E-03 0,0216479 ! phospholipid efflux GO:0033700 16 10 0,000 7,981E-03 0,0216224 ! hippocampus development GO:0021766 19 10 0,000 7,981E-03 0,02159696 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 7,981E-03 0,02157159 ! blood vessel remodeling GO:0001974 21 10 0,000 7,981E-03 0,02154627 ! positive regulation of heart contraction GO:0045823 14 10 0,000 7,981E-03 0,02152101 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 7,981E-03 0,02149581 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 7,981E-03 0,02147067 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 7,981E-03 0,02144558 ! pathogenesis GO:0009405 13 10 0,000 7,981E-03 0,02142056 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 7,981E-03 0,02139559 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 7,981E-03 0,02137069 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 7,981E-03 0,02134584 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 7,981E-03 0,02132104 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 7,981E-03 0,02129631 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 7,981E-03 0,02127163 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 7,981E-03 0,02124701 ! melanocyte differentiation GO:0030318 15 10 0,000 7,981E-03 0,02122245 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 7,981E-03 0,02119794 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 7,981E-03 0,02117349 ! reverse cholesterol transport GO:0043691 16 10 0,000 7,981E-03 0,0211491 ! response to X-ray GO:0010165 16 10 0,000 7,981E-03 0,02112476 ! B cell proliferation GO:0042100 14 10 0,000 7,981E-03 0,02110048 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 7,981E-03 0,02107626 ! regulation of sodium ion transport GO:0002028 15 10 0,000 7,981E-03 0,02105209 ! forebrain cell migration GO:0021885 17 10 0,000 7,981E-03 0,02102797 ! lipid digestion GO:0044241 15 10 0,000 7,981E-03 0,02100391 ! phagocytosis, engulfment GO:0006911 20 10 0,000 7,981E-03 0,02097991 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 7,981E-03 0,02095596 ! UV protection GO:0009650 14 10 0,000 7,981E-03 0,02093206 ! entry into host cell GO:0030260 20 10 0,000 7,981E-03 0,02090822 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 7,981E-03 0,02088444 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 7,981E-03 0,0208607 ! negative regulation of ossification GO:0030279 19 10 0,000 7,981E-03 0,02083703 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 7,981E-03 0,0208134 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 7,981E-03 0,02078983 ! regulation of bone resorption GO:0045124 24 10 0,000 7,981E-03 0,02076631 ! alpha-beta T cell activation GO:0046631 16 10 0,000 7,981E-03 0,02074285 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 7,981E-03 0,02071943 ! regulation of organ growth GO:0046620 11 10 0,000 7,981E-03 0,02069608 ! response to dsRNA GO:0043331 18 10 0,000 7,981E-03 0,02067277 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 7,981E-03 0,02064952 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 7,981E-03 0,02062631 ! embryonic axis specification GO:0000578 12 10 0,000 7,981E-03 0,02060316 ! regulation of B cell differentiation GO:0045577 16 10 0,000 7,981E-03 0,02058007 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 7,981E-03 0,02055702 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 7,981E-03 0,02053403 ! cranial nerve development GO:0021545 12 10 0,000 7,981E-03 0,02051108 ! fucose catabolic process GO:0019317 16 10 0,000 7,981E-03 0,02048819 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 7,981E-03 0,02046535 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 7,981E-03 0,02044256 ! protein sumoylation GO:0016925 12 10 0,000 7,981E-03 0,02041982 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 7,981E-03 0,02039713 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 7,981E-03 0,02037449 ! zymogen activation GO:0031638 14 10 0,000 7,981E-03 0,02035191 ! salivary gland development GO:0007431 22 10 0,000 7,981E-03 0,02032937 ! negative regulation of neurological system process GO:0031645 19 10 0,000 7,981E-03 0,02030688 ! glutathione biosynthetic process GO:0006750 11 10 0,000 7,981E-03 0,02028444 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 7,981E-03 0,02026205 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 7,981E-03 0,02023971 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 7,981E-03 0,02021742 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 7,981E-03 0,02019518 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 7,981E-03 0,02017299 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 7,981E-03 0,02015084 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 7,981E-03 0,02012875 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 7,981E-03 0,0201067 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 7,981E-03 0,0200847 ! detection of bacterium GO:0016045 10 10 0,000 7,981E-03 0,02006275 ! embryonic gut development GO:0048566 11 10 0,000 7,981E-03 0,02004085 ! activation of innate immune response GO:0002218 10 10 0,000 7,981E-03 0,020019 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 7,981E-03 0,01999719 ! cardiac cell differentiation GO:0035051 16 10 0,000 7,981E-03 0,01997543 ! developmental induction GO:0031128 13 10 0,000 7,981E-03 0,01995372 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 7,981E-03 0,01993205 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 7,981E-03 0,01991043 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 7,981E-03 0,01988886 ! negative regulation of immune effector process GO:0002698 16 10 0,000 7,981E-03 0,01986734 ! rRNA transcription GO:0009303 17 11 0,000 8,776E-03 0,02182233 ! respiratory burst GO:0045730 14 11 0,000 8,776E-03 0,02179877 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 8,776E-03 0,02177525 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 8,776E-03 0,02175179 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 8,776E-03 0,02172837 ! virus-host interaction GO:0019048 17 11 0,000 8,776E-03 0,02170501 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 8,776E-03 0,0216817 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 8,776E-03 0,02165843 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 8,776E-03 0,02163522 ! Golgi vesicle budding GO:0048194 17 11 0,000 8,776E-03 0,02161205 ! RNA polyadenylation GO:0043631 19 11 0,000 8,776E-03 0,02158894 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 8,776E-03 0,02156587 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 8,776E-03 0,02154286 ! mating GO:0007618 14 11 0,000 8,776E-03 0,02151989 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 8,776E-03 0,02149697 ! T cell proliferation GO:0042098 20 11 0,000 8,776E-03 0,0214741 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 8,776E-03 0,02145128 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 8,776E-03 0,02142851 ! bone resorption GO:0045453 16 11 0,000 8,776E-03 0,02140579 ! regulated secretory pathway GO:0045055 14 11 0,000 8,776E-03 0,02138311 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 8,776E-03 0,02136049 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 8,776E-03 0,02133791 ! regulation of mRNA processing GO:0050684 18 11 0,000 8,776E-03 0,02131537 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 8,776E-03 0,02129289 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 8,776E-03 0,02127045 ! syncytium formation GO:0006949 15 11 0,000 8,776E-03 0,02124806 ! plasma membrane organization GO:0007009 18 11 0,000 8,776E-03 0,02122572 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 8,776E-03 0,02120342 ! focal adhesion formation GO:0048041 24 11 0,000 8,776E-03 0,02118117 ! mitotic spindle organization GO:0007052 15 11 0,000 8,776E-03 0,02115897 ! regulation of intracellular pH GO:0051453 17 11 0,000 8,776E-03 0,02113682 ! membrane protein proteolysis GO:0033619 18 11 0,000 8,776E-03 0,02111471 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 8,776E-03 0,02109264 ! adult heart development GO:0007512 11 11 0,000 8,776E-03 0,02107062 ! chondrocyte differentiation GO:0002062 17 11 0,000 8,776E-03 0,02104865 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 8,776E-03 0,02102673 ! temperature homeostasis GO:0001659 16 11 0,000 8,776E-03 0,02100485 ! L-glutamate transport GO:0015813 16 11 0,000 8,776E-03 0,02098301 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 8,776E-03 0,02096122 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 8,776E-03 0,02093948 ! protein targeting to peroxisome GO:0006625 20 11 0,000 8,776E-03 0,02091778 ! stem cell development GO:0048864 29 11 0,000 8,776E-03 0,02089613 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 8,776E-03 0,02087452 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 8,776E-03 0,02085295 ! regulation of phagocytosis GO:0050764 14 11 0,000 8,776E-03 0,02083143 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 8,776E-03 0,02080996 ! vasoconstriction GO:0042310 15 11 0,000 8,776E-03 0,02078853 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 8,776E-03 0,02076714 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 8,776E-03 0,02074579 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 8,776E-03 0,0207245 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 8,776E-03 0,02070324 ! ribosome assembly GO:0042255 13 11 0,000 8,776E-03 0,02068203 ! nitric oxide metabolic process GO:0046209 14 11 0,000 8,776E-03 0,02066086 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 8,776E-03 0,02063973 ! chromatin silencing GO:0006342 19 11 0,000 8,776E-03 0,02061865 ! nucleosome positioning GO:0016584 13 11 0,000 8,776E-03 0,02059761 ! T cell homeostasis GO:0043029 20 11 0,000 8,776E-03 0,02057661 ! regulation of isotype switching GO:0045191 19 11 0,000 8,776E-03 0,02055566 ! regulation of leukocyte migration GO:0002685 24 11 0,000 8,776E-03 0,02053475 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 8,776E-03 0,02051388 ! protein-chromophore linkage GO:0018298 13 11 0,000 8,776E-03 0,02049305 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 8,776E-03 0,02047227 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 8,776E-03 0,02045153 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 8,776E-03 0,02043083 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 8,776E-03 0,02041017 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 8,776E-03 0,02038955 ! male genitalia development GO:0030539 13 11 0,000 8,776E-03 0,02036898 ! cholesterol efflux GO:0033344 19 11 0,000 8,776E-03 0,02034845 ! digestive tract morphogenesis GO:0048546 15 11 0,000 8,776E-03 0,02032795 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 8,776E-03 0,0203075 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 8,776E-03 0,02028709 ! negative regulation of glucose import GO:0046325 14 11 0,000 8,776E-03 0,02026673 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 8,776E-03 0,0202464 ! regulation of organic acid transport GO:0032890 17 11 0,000 8,776E-03 0,02022611 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 8,776E-03 0,02020586 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 8,776E-03 0,02018566 ! mRNA 3'-end processing GO:0031124 19 11 0,000 8,776E-03 0,02016549 ! lysogeny GO:0030069 18 11 0,000 8,776E-03 0,02014537 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 8,776E-03 0,02012528 ! acrosome reaction GO:0007340 13 11 0,000 8,776E-03 0,02010524 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 8,776E-03 0,02008523 ! lactation GO:0007595 20 12 0,000 9,571E-03 0,02188125 ! reproductive cellular process GO:0048610 14 12 0,000 9,571E-03 0,02185952 ! tRNA modification GO:0006400 14 12 0,000 9,571E-03 0,02183783 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 9,571E-03 0,02181619 ! positive regulation of blood pressure GO:0045777 16 12 0,000 9,571E-03 0,02179459 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 9,571E-03 0,02177303 ! 'de novo' protein folding GO:0006458 18 12 0,000 9,571E-03 0,02175152 ! dicarboxylic acid transport GO:0006835 22 12 0,000 9,571E-03 0,02173005 ! non-recombinational repair GO:0000726 19 12 0,000 9,571E-03 0,02170862 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 9,571E-03 0,02168723 ! peroxisomal transport GO:0043574 21 12 0,000 9,571E-03 0,02166588 ! cartilage condensation GO:0001502 18 12 0,000 9,571E-03 0,02164458 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 9,571E-03 0,02162332 ! cytokine biosynthetic process GO:0042089 16 12 0,000 9,571E-03 0,0216021 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 9,571E-03 0,02158092 ! heart looping GO:0001947 15 12 0,000 9,571E-03 0,02155978 ! palate development GO:0060021 15 12 0,000 9,571E-03 0,02153869 ! positive regulation of cell growth GO:0030307 16 12 0,000 9,571E-03 0,02151763 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 9,571E-03 0,02149662 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 9,571E-03 0,02147565 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 9,571E-03 0,02145471 ! arginine metabolic process GO:0006525 13 12 0,000 9,571E-03 0,02143382 ! glycoprotein catabolic process GO:0006516 19 12 0,000 9,571E-03 0,02141297 ! methionine metabolic process GO:0006555 13 12 0,000 9,571E-03 0,02139216 ! tyrosine metabolic process GO:0006570 14 12 0,000 9,571E-03 0,0213714 ! Golgi organization GO:0007030 18 12 0,000 9,571E-03 0,02135067 ! cell-cell junction assembly GO:0007043 18 12 0,000 9,571E-03 0,02132998 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 9,571E-03 0,02130933 ! monoamine transport GO:0015844 13 12 0,000 9,571E-03 0,02128872 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 9,571E-03 0,02126815 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 9,571E-03 0,02124762 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 9,571E-03 0,02122713 ! L-amino acid transport GO:0015807 20 12 0,000 9,571E-03 0,02120668 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 9,571E-03 0,02118627 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 9,571E-03 0,0211659 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 9,571E-03 0,02114557 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 9,571E-03 0,02112528 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 9,571E-03 0,02110502 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 9,571E-03 0,02108481 ! cerebellum development GO:0021549 13 12 0,000 9,571E-03 0,02106463 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 9,571E-03 0,02104449 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 9,571E-03 0,02102439 ! histone acetylation GO:0016573 23 12 0,000 9,571E-03 0,02100433 ! histone methylation GO:0016571 15 12 0,000 9,571E-03 0,02098431 ! autonomic nervous system development GO:0048483 23 12 0,000 9,571E-03 0,02096432 ! gland morphogenesis GO:0022612 23 12 0,000 9,571E-03 0,02094437 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 9,571E-03 0,02092447 ! peptidyl-lysine modification GO:0018205 18 12 0,000 9,571E-03 0,02090459 ! negative regulation of protein secretion GO:0050709 20 12 0,000 9,571E-03 0,02088476 ! response to gamma radiation GO:0010332 20 12 0,000 9,571E-03 0,02086496 ! regulation of epidermis development GO:0045682 17 12 0,000 9,571E-03 0,02084521 ! intestinal absorption GO:0050892 19 12 0,000 9,571E-03 0,02082548 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 9,571E-03 0,0208058 ! cAMP biosynthetic process GO:0006171 20 12 0,000 9,571E-03 0,02078615 ! regulation of mRNA stability GO:0043488 27 12 0,000 9,571E-03 0,02076654 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 9,571E-03 0,02074697 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 9,571E-03 0,02072744 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 9,571E-03 0,02070794 ! RNA 3'-end processing GO:0031123 20 12 0,000 9,571E-03 0,02068847 ! microspike assembly GO:0030035 23 12 0,000 9,571E-03 0,02066905 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 9,571E-03 0,02064966 ! response to cold GO:0009409 14 12 0,000 9,571E-03 0,02063031 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 0,01036437 0,02232028 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,01036437 0,0222994 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,01036437 0,02227856 ! cGMP metabolic process GO:0046068 16 13 0,000 0,01036437 0,02225776 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,01036437 0,02223699 ! water transport GO:0006833 17 13 0,000 0,01036437 0,02221627 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,01036437 0,02219558 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,01036437 0,02217494 ! lipid localization GO:0010876 24 13 0,000 0,01036437 0,02215433 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,01036437 0,02213376 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,01036437 0,02211323 ! organelle fusion GO:0048284 28 13 0,000 0,01036437 0,02209273 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,01036437 0,02207227 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,01036437 0,02205186 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,01036437 0,02203148 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,01036437 0,02201113 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,01036437 0,02199083 ! response to hexose stimulus GO:0009746 19 13 0,000 0,01036437 0,02197056 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,01036437 0,02195033 ! glutamate metabolic process GO:0006536 18 13 0,000 0,01036437 0,02193013 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,01036437 0,02190998 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,01036437 0,02188986 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,01036437 0,02186978 ! NAD metabolic process GO:0019674 21 13 0,000 0,01036437 0,02184973 ! exocrine system development GO:0035272 27 13 0,000 0,01036437 0,02182972 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,01036437 0,02180975 ! bone mineralization GO:0030282 15 13 0,000 0,01036437 0,02178981 ! regulation of exocytosis GO:0017157 17 13 0,000 0,01036437 0,02176991 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,01036437 0,02175005 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,01036437 0,02173022 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,01036437 0,02171043 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,01036437 0,02169068 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,01036437 0,02167096 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,01036437 0,02165128 ! genitalia development GO:0048806 15 13 0,000 0,01036437 0,02163163 ! regulation of cellular pH GO:0030641 20 13 0,000 0,01036437 0,02161202 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 0,01036437 0,02159244 ! cellular pigmentation GO:0033059 24 13 0,000 0,01036437 0,0215729 ! tissue regeneration GO:0042246 21 13 0,000 0,01036437 0,0215534 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,01036437 0,02153393 ! cofactor transport GO:0051181 19 13 0,000 0,01036437 0,02151449 ! NADP metabolic process GO:0006739 18 13 0,000 0,01036437 0,02149509 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,01036437 0,02147573 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,01036437 0,0214564 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,01036437 0,0214371 ! gas transport GO:0015669 18 13 0,000 0,01036437 0,02141784 ! regulation of RNA stability GO:0043487 28 13 0,000 0,01036437 0,02139861 ! heme biosynthetic process GO:0006783 20 13 0,000 0,01036437 0,02137942 ! regulation of axon extension GO:0030516 23 13 0,000 0,01036437 0,02136027 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,01036437 0,02134114 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,01036437 0,02132205 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,01036437 0,021303 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,01036437 0,02128398 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,01036437 0,02126499 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,01036437 0,02124604 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,01115749 0,02285148 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,01115749 0,02283115 ! superoxide anion generation GO:0042554 18 14 0,000 0,01115749 0,02281086 ! neuron maturation GO:0042551 21 14 0,000 0,01115749 0,0227906 ! regulation of S phase GO:0033261 18 14 0,000 0,01115749 0,02277038 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,01115749 0,02275019 ! myotube differentiation GO:0014902 21 14 0,000 0,01115749 0,02273004 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 0,01115749 0,02270993 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,01115749 0,02268985 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,01115749 0,0226698 ! inositol metabolic process GO:0006020 20 14 0,000 0,01115749 0,02264979 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,01115749 0,02262982 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,01115749 0,02260988 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,01115749 0,02258998 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,01115749 0,02257011 ! gene silencing by RNA GO:0031047 20 14 0,000 0,01115749 0,02255028 ! response to cAMP GO:0051591 19 14 0,000 0,01115749 0,02253048 ! limbic system development GO:0021761 25 14 0,000 0,01115749 0,02251072 ! startle response GO:0001964 21 14 0,000 0,01115749 0,02249099 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,01115749 0,02247129 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,01115749 0,02245163 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,01115749 0,02243201 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,01115749 0,02241242 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,01115749 0,02239286 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,01115749 0,02237334 ! glycine metabolic process GO:0006544 22 14 0,000 0,01115749 0,02235385 ! pituitary gland development GO:0021983 23 14 0,000 0,01115749 0,02233439 ! cellular response to starvation GO:0009267 21 14 0,000 0,01115749 0,02231497 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,01115749 0,02229558 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,01115749 0,02227623 ! regulation of heart rate GO:0002027 23 14 0,000 0,01115749 0,02225691 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,01115749 0,02223762 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,01115749 0,02221837 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,01115749 0,02219915 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,01115749 0,02217996 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,01115749 0,02216081 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,01115749 0,02214169 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,01115749 0,0221226 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,01115749 0,02210355 ! axon cargo transport GO:0008088 27 14 0,000 0,01115749 0,02208452 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,01115749 0,02206554 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,01115749 0,02204658 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,01115749 0,02202765 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,01115749 0,02200876 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,01115749 0,0219899 ! mRNA splice site selection GO:0006376 26 14 0,000 0,01115749 0,02197108 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,01115749 0,02195228 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,01115749 0,02193352 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,01115749 0,02191479 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,01115749 0,02189609 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,01115749 0,02187742 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,01115749 0,02185879 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,01115749 0,02184019 ! muscle maintenance GO:0046716 19 14 0,000 0,01115749 0,02182161 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,01115749 0,02180307 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,01115749 0,02178456 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,01115749 0,02176609 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,01115749 0,02174764 ! cell killing GO:0001906 20 14 0,000 0,01115749 0,02172923 ! release of cytochrome c from mitochondria GO:0001836 23 14 0,000 0,01115749 0,02171084 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,01115749 0,02169249 ! cilium assembly GO:0042384 20 14 0,000 0,01115749 0,02167417 ! peptide hormone secretion GO:0030072 23 14 0,000 0,01115749 0,02165588 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,01195001 0,02317455 ! positive regulation of cell size GO:0045793 20 15 0,000 0,01195001 0,02315503 ! metencephalon development GO:0022037 19 15 0,000 0,01195001 0,02313554 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,01195001 0,02311608 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,01195001 0,02309666 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,01195001 0,02307726 ! skin development GO:0043588 25 15 0,000 0,01195001 0,0230579 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,01195001 0,02303858 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,01195001 0,02301928 ! lipid phosphorylation GO:0046834 23 15 0,000 0,01195001 0,02300002 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,01195001 0,02298079 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,01195001 0,02296159 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,01195001 0,02294242 ! bile acid metabolic process GO:0008206 22 15 0,000 0,01195001 0,02292329 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,01195001 0,02290418 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,01195001 0,02288511 ! adult walking behavior GO:0007628 25 15 0,000 0,01195001 0,02286607 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,01195001 0,02284707 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,01195001 0,02282809 ! myoblast differentiation GO:0045445 27 15 0,000 0,01195001 0,02280915 ! centrosome cycle GO:0007098 16 15 0,000 0,01195001 0,02279023 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,01195001 0,02277135 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,01195001 0,0227525 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,01195001 0,02273368 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,01195001 0,02271489 ! cerebral cortex development GO:0021987 29 15 0,000 0,01195001 0,02269614 ! response to osmotic stress GO:0006970 22 15 0,000 0,01195001 0,02267741 ! vesicle coating GO:0006901 25 15 0,000 0,01195001 0,02265871 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,01195001 0,02264005 ! DNA integration GO:0015074 22 15 0,000 0,01195001 0,02262142 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,01195001 0,02260281 ! peptide secretion GO:0002790 27 15 0,000 0,01195001 0,02258424 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,01195001 0,0225657 ! regulation of vasodilation GO:0042312 24 15 0,000 0,01195001 0,02254719 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,01195001 0,02252871 ! neuron recognition GO:0008038 22 15 0,000 0,01195001 0,02251025 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,01195001 0,02249183 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,01195001 0,02247344 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,01195001 0,02245508 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,01195001 0,02243675 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,01195001 0,02241845 ! biomineral formation GO:0031214 18 15 0,000 0,01195001 0,02240018 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,01195001 0,02238194 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,01195001 0,02236373 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,01195001 0,02234555 ! dopamine metabolic process GO:0042417 30 15 0,000 0,01195001 0,02232739 ! organic cation transport GO:0015695 19 15 0,000 0,01195001 0,02230927 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,01195001 0,02229118 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,01195001 0,02227311 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,01195001 0,02225508 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,01195001 0,02223707 ! defense response to virus GO:0051607 27 15 0,000 0,01195001 0,0222191 ! peptide hormone processing GO:0016486 19 15 0,000 0,01195001 0,02220115 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,01195001 0,02218323 ! protein secretion GO:0009306 27 16 0,000 0,01274194 0,02363425 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,01274194 0,0236152 ! hormone secretion GO:0046879 25 16 0,000 0,01274194 0,02359619 ! bone remodeling GO:0046849 24 16 0,000 0,01274194 0,02357721 ! endothelial cell migration GO:0043542 22 16 0,000 0,01274194 0,02355825 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,01274194 0,02353933 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,01274194 0,02352044 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,01274194 0,02350158 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,01274194 0,02348275 ! glial cell development GO:0021782 24 16 0,000 0,01274194 0,02346395 ! patterning of blood vessels GO:0001569 24 16 0,000 0,01274194 0,02344517 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,01274194 0,02342643 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,01274194 0,02340772 ! protein polyubiquitination GO:0000209 26 16 0,000 0,01274194 0,02338904 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,01274194 0,02337039 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,01274194 0,02335177 ! regulation of protein binding GO:0043393 27 16 0,000 0,01274194 0,02333317 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,01274194 0,02331461 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,01274194 0,02329608 ! protein export from nucleus GO:0006611 24 16 0,000 0,01274194 0,02327758 ! negative regulation of immune response GO:0050777 28 16 0,000 0,01274194 0,0232591 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,01274194 0,02324066 ! DNA replication initiation GO:0006270 25 16 0,000 0,01274194 0,02322224 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,01274194 0,02320385 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,01274194 0,0231855 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,01274194 0,02316717 ! diencephalon development GO:0021536 25 16 0,000 0,01274194 0,02314887 ! oogenesis GO:0048477 23 16 0,000 0,01274194 0,0231306 ! neural crest cell migration GO:0001755 24 16 0,000 0,01274194 0,02311236 ! G1 phase GO:0051318 27 16 0,000 0,01274194 0,02309414 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,01274194 0,02307596 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,01274194 0,0230578 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,01274194 0,02303968 ! steroid catabolic process GO:0006706 22 16 0,000 0,01274194 0,02302158 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,01274194 0,02300351 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,01274194 0,02298546 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,01274194 0,02296745 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,01274194 0,02294947 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,01274194 0,02293151 ! sperm-egg recognition GO:0035036 16 16 0,000 0,01274194 0,02291358 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,01274194 0,02289568 ! nerve development GO:0021675 18 16 0,000 0,01274194 0,0228778 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,01274194 0,02285996 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,01274194 0,02284214 ! negative regulation of translation GO:0017148 22 16 0,000 0,01274194 0,02282435 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,01353329 0,024223 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,01353329 0,02420417 ! negative regulation of defense response GO:0031348 19 17 0,000 0,01353329 0,02418536 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,01353329 0,02416658 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,01353329 0,02414783 ! glycerol metabolic process GO:0006071 20 17 0,000 0,01353329 0,02412912 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,01353329 0,02411042 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,01353329 0,02409176 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,01353329 0,02407313 ! signal complex assembly GO:0007172 29 17 0,000 0,01353329 0,02405453 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,01353329 0,02403595 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,01353329 0,02401741 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,01353329 0,02399889 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,01353329 0,0239804 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,01353329 0,02396194 ! memory GO:0007613 25 17 0,000 0,01353329 0,02394351 ! keratinization GO:0031424 17 17 0,000 0,01353329 0,0239251 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,01353329 0,02390673 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,01353329 0,02388838 ! retinoid metabolic process GO:0001523 22 17 0,000 0,01353329 0,02387006 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,01353329 0,02385177 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,01353329 0,02383351 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,01353329 0,02381527 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,01353329 0,02379706 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,01353329 0,02377888 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,01353329 0,02376073 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 0,000 0,01353329 0,02374261 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,01353329 0,02372451 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,01353329 0,02370644 ! membrane budding GO:0006900 29 17 0,000 0,01353329 0,0236884 ! heme metabolic process GO:0042168 27 17 0,000 0,01353329 0,02367039 ! actin filament bundle formation GO:0051017 26 17 0,000 0,01353329 0,0236524 ! neuromuscular junction development GO:0007528 23 17 0,000 0,01353329 0,02363444 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,01353329 0,02361651 ! body fluid secretion GO:0007589 27 17 0,000 0,01353329 0,0235986 ! stem cell differentiation GO:0048863 36 17 0,000 0,01353329 0,02358073 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,01353329 0,02356288 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,01353329 0,02354505 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,01353329 0,02352726 ! sensory perception of pain GO:0019233 23 17 0,000 0,01353329 0,02350949 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,01353329 0,02349174 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,01353329 0,02347403 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,01353329 0,02345634 ! synaptogenesis GO:0007416 24 17 0,000 0,01353329 0,02343867 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,01353329 0,02342104 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,01353329 0,02340343 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,01353329 0,02338584 ! cell-cell junction organization GO:0045216 25 17 0,000 0,01353329 0,02336829 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,01353329 0,02335076 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,01353329 0,02333325 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,01353329 0,02331577 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,01353329 0,02329832 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,01353329 0,0232809 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,01353329 0,0232635 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,01432404 0,0246044 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,01432404 0,02458604 ! positive regulation of translation GO:0045727 28 18 0,000 0,01432404 0,02456771 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,01432404 0,0245494 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,01432404 0,02453112 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,01432404 0,02451287 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,01432404 0,02449464 ! cAMP metabolic process GO:0046058 33 18 0,000 0,01432404 0,02447644 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,01432404 0,02445827 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,01432404 0,02444013 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,01432404 0,02442201 ! axis specification GO:0009798 26 18 0,000 0,01432404 0,02440392 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,01432404 0,02438586 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,01432404 0,02436782 ! pancreas development GO:0031016 26 18 0,000 0,01432404 0,02434981 ! apoptotic mitochondrial changes GO:0008637 29 18 0,000 0,01432404 0,02433183 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,01432404 0,02431387 ! glutamine metabolic process GO:0006541 23 18 0,000 0,01432404 0,02429594 ! response to retinoic acid GO:0032526 25 18 0,000 0,01432404 0,02427804 ! pigmentation during development GO:0048066 31 18 0,000 0,01432404 0,02426016 ! central nervous system neuron development GO:0021954 30 18 0,000 0,01432404 0,02424231 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,01432404 0,02422448 ! fucose metabolic process GO:0006004 26 18 0,000 0,01432404 0,02420668 ! response to fungus GO:0009620 19 18 0,000 0,01432404 0,02418891 ! peptide cross-linking GO:0018149 31 18 0,000 0,01432404 0,02417116 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,01432404 0,02415344 ! heart process GO:0003015 27 18 0,000 0,01432404 0,02413575 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,01432404 0,02411808 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,01432404 0,02410044 ! visual learning GO:0008542 35 18 0,000 0,01432404 0,02408282 ! somitogenesis GO:0001756 24 18 0,000 0,01432404 0,02406523 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,01432404 0,02404766 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,01432404 0,02403012 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,01432404 0,02401261 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,01432404 0,02399512 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,01432404 0,02397765 ! vitamin transport GO:0051180 24 18 0,000 0,01432404 0,02396021 ! hormone transport GO:0009914 27 18 0,000 0,01432404 0,0239428 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,01432404 0,02392541 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,01432404 0,02390805 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,01432404 0,02389071 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,01432404 0,0238734 ! cell-cell recognition GO:0009988 20 18 0,000 0,01432404 0,02385612 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,01432404 0,02383885 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,01432404 0,02382162 ! regulation of glucose import GO:0046324 21 18 0,000 0,01432404 0,0238044 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,01432404 0,02378722 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,01432404 0,02377005 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,01432404 0,02375292 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,01432404 0,0237358 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,01511421 0,02502713 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,01511421 0,02500912 ! positive regulation of fibroblast proliferation GO:0048146 27 19 0,000 0,01511421 0,02499114 ! positive regulation of ossification GO:0045778 30 19 0,000 0,01511421 0,02497319 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,01511421 0,02495526 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,01511421 0,02493736 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,01511421 0,02491948 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,01511421 0,02490163 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,01511421 0,02488381 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,01511421 0,02486601 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,01511421 0,02484823 ! regeneration GO:0031099 32 19 0,000 0,01511421 0,02483048 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,01511421 0,02481276 ! response to alkaloid GO:0043279 32 19 0,000 0,01511421 0,02479506 ! sensory perception of taste GO:0050909 23 19 0,000 0,01511421 0,02477739 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,01511421 0,02475974 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 0,000 0,01511421 0,02474212 ! smooth muscle contraction GO:0006939 36 19 0,000 0,01511421 0,02472452 ! peroxisome organization GO:0007031 29 19 0,000 0,01511421 0,02470695 ! digestive system process GO:0022600 30 19 0,000 0,01511421 0,0246894 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,01511421 0,02467188 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,01511421 0,02465438 ! response to vitamin A GO:0033189 26 19 0,000 0,01511421 0,02463691 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,01511421 0,02461946 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,01511421 0,02460204 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,01511421 0,02458464 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,01511421 0,02456726 ! response to starvation GO:0042594 30 19 0,000 0,01511421 0,02454991 ! sex determination GO:0007530 29 19 0,000 0,01511421 0,02453259 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,01511421 0,02451529 ! plasma membrane fusion GO:0045026 23 19 0,000 0,01511421 0,02449801 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,01511421 0,02448076 ! cytolysis GO:0019835 20 19 0,000 0,01511421 0,02446353 ! renal system process GO:0003014 35 19 0,000 0,01511421 0,02444633 ! vasodilation GO:0042311 33 19 0,000 0,01511421 0,02442915 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,01511421 0,02441199 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,01511421 0,02439486 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,01511421 0,02437775 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,01511421 0,02436067 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,01511421 0,02434361 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,01511421 0,02432658 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,01511421 0,02430956 ! sarcomere organization GO:0045214 23 19 0,000 0,01511421 0,02429258 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,01511421 0,02427561 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,01511421 0,02425867 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,01511421 0,02424176 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,01511421 0,02422486 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,01511421 0,02420799 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,01511421 0,02419115 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,01511421 0,02417432 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,01511421 0,02415752 ! protein stabilization GO:0050821 26 19 0,000 0,01511421 0,02414075 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,01590379 0,02538425 ! iron ion transport GO:0006826 37 20 0,000 0,01590379 0,02536665 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,01590379 0,02534907 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,01590379 0,02533151 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,01590379 0,02531398 ! response to vitamin GO:0033273 29 20 0,000 0,01590379 0,02529648 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,01590379 0,025279 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,01590379 0,02526154 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,01590379 0,0252441 ! spinal cord development GO:0021510 31 20 0,000 0,01590379 0,02522669 ! response to ethanol GO:0045471 37 20 0,000 0,01590379 0,02520931 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,01590379 0,02519195 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 0,000 0,01590379 0,02517461 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,01590379 0,02515729 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,01590379 0,02514 ! chromosome condensation GO:0030261 31 20 0,000 0,01590379 0,02512274 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,01590379 0,0251055 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,01590379 0,02508828 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,01590379 0,02507108 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,01590379 0,02505391 ! pallium development GO:0021543 38 20 0,000 0,01590379 0,02503676 ! DNA modification GO:0006304 28 20 0,000 0,01590379 0,02501964 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,01590379 0,02500253 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,01590379 0,02498546 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,01590379 0,0249684 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,01590379 0,02495137 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,01590379 0,02493436 ! positive regulation of B cell activation GO:0050871 31 20 0,000 0,01590379 0,02491738 ! collagen catabolic process GO:0030574 25 20 0,000 0,01590379 0,02490041 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,01590379 0,02488347 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,01590379 0,02486656 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,01590379 0,02484966 ! actin filament-based movement GO:0030048 34 20 0,000 0,01590379 0,02483279 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,01669278 0,02604707 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,01669278 0,02602941 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,01669278 0,02601178 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,01669278 0,02599417 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 0,000 0,01669278 0,02597658 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,01669278 0,02595902 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,01669278 0,02594148 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,01669278 0,02592396 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,01669278 0,02590647 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,01669278 0,025889 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,01669278 0,02587155 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,01669278 0,02585413 ! protein amino acid acylation GO:0043543 37 21 0,000 0,01669278 0,02583673 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,01669278 0,02581936 ! vesicle docking GO:0048278 27 21 0,000 0,01669278 0,02580201 ! phototransduction GO:0007602 25 21 0,000 0,01669278 0,02578468 ! dendrite development GO:0016358 35 21 0,000 0,01669278 0,02576737 ! visual behavior GO:0007632 39 21 0,000 0,01669278 0,02575009 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,01669278 0,02573283 ! ovarian follicle development GO:0001541 30 21 0,000 0,01669278 0,0257156 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,01669278 0,02569838 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,01669278 0,02568119 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,01669278 0,02566403 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,01669278 0,02564688 ! cell aging GO:0007569 32 21 0,000 0,01669278 0,02562976 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,01669278 0,02561266 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,01669278 0,02559559 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,01669278 0,02557854 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,01669278 0,02556151 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,01669278 0,0255445 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,01669278 0,02552752 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,01669278 0,02551055 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,01669278 0,02549361 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,01669278 0,0254767 ! fatty acid transport GO:0015908 30 21 0,000 0,01669278 0,0254598 ! immunoglobulin production GO:0002377 33 21 0,000 0,01669278 0,02544293 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,01669278 0,02542608 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,01669278 0,02540925 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,01669278 0,02539245 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,01669278 0,02537567 ! cellular response to extracellular stimulus GO:0031668 32 21 0,000 0,01669278 0,02535891 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,01669278 0,02534217 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,01669278 0,02532545 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,01669278 0,02530876 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,01669278 0,02529208 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,01669278 0,02527543 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,01669278 0,02525881 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,01669278 0,0252422 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,01669278 0,02522561 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,01669278 0,02520905 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,01669278 0,02519251 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,01748118 0,02636506 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,01748118 0,02634778 ! regulation of fibroblast proliferation GO:0048145 35 22 0,000 0,01748118 0,02633052 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,01748118 0,02631329 ! viral genome replication GO:0019079 29 22 0,000 0,01748118 0,02629608 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,01748118 0,0262789 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,01748118 0,02626173 ! leukocyte adhesion GO:0007159 38 22 0,000 0,01748118 0,02624459 ! molting cycle process GO:0022404 40 22 0,000 0,01748118 0,02622747 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,01748118 0,02621037 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,01748118 0,0261933 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,01748118 0,02617624 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,01748118 0,02615921 ! vasculogenesis GO:0001570 33 22 0,000 0,01748118 0,0261422 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,01748118 0,02612522 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,01748118 0,02610825 GO:0010810|regulation of cell-substrate adhesion, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,01748118 0,02609131 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,01748118 0,02607439 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,01748118 0,02605749 ! lysosome organization GO:0007040 37 22 0,000 0,01748118 0,02604062 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,01748118 0,02602376 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,01748118 0,02600693 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,01748118 0,02599012 ! regulation of behavior GO:0050795 38 22 0,000 0,01748118 0,02597333 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,01748118 0,02595656 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,01748118 0,02593981 ! membrane depolarization GO:0051899 35 22 0,000 0,01748118 0,02592309 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,01748118 0,02590639 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,01748118 0,0258897 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,01748118 0,02587304 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,01748118 0,02585641 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,01748118 0,02583979 ! blastocyst development GO:0001824 37 22 0,000 0,01748118 0,02582319 ! neural tube closure GO:0001843 33 22 0,000 0,01748118 0,02580662 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,01748118 0,02579006 ! protein tetramerization GO:0051262 39 22 0,000 0,01748118 0,02577353 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,01826899 0,0269178 ! neuron fate commitment GO:0048663 32 23 0,000 0,01826899 0,02690057 ! embryonic pattern specification GO:0009880 31 23 0,000 0,01826899 0,02688336 ! positive regulation of cell adhesion GO:0045785 37 23 0,000 0,01826899 0,02686617 ! myelination GO:0042552 35 23 0,000 0,01826899 0,026849 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,01826899 0,02683186 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,01826899 0,02681473 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,01826899 0,02679763 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,01826899 0,02678055 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,01826899 0,02676349 ! vesicle targeting GO:0006903 32 23 0,000 0,01826899 0,02674646 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,01826899 0,02672944 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,01826899 0,02671245 ! osteoblast differentiation GO:0001649 40 23 0,000 0,01826899 0,02669548 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,01826899 0,02667853 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,01826899 0,0266616 ! interaction with host GO:0051701 37 23 0,000 0,01826899 0,0266447 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,01826899 0,02662781 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,01826899 0,02661095 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,01826899 0,02659411 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,01826899 0,02657728 ! negative regulation of phosphorylation GO:0042326 41 23 0,000 0,01826899 0,02656048 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,01826899 0,02654371 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,01826899 0,02652695 ! cell fate determination GO:0001709 45 23 0,000 0,01826899 0,02651021 ! pentose metabolic process GO:0019321 31 23 0,000 0,01826899 0,0264935 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,01826899 0,0264768 ! spermatid development GO:0007286 33 23 0,000 0,01826899 0,02646013 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,01826899 0,02644348 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,01826899 0,02642685 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,01826899 0,02641024 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,01826899 0,02639365 ! telomere organization GO:0032200 32 23 0,000 0,01826899 0,02637708 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,01826899 0,02636053 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,01826899 0,026344 ! regulation of amine transport GO:0051952 38 23 0,000 0,01826899 0,0263275 ! liver development GO:0001889 40 23 0,000 0,01826899 0,02631101 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,01905622 0,02742761 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,01905622 0,02741045 ! initiation of viral infection GO:0019059 42 24 0,000 0,01905622 0,02739332 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,01905622 0,02737621 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,01905622 0,02735912 ! superoxide metabolic process GO:0006801 32 24 0,000 0,01905622 0,02734205 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,01905622 0,02732501 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! insulin receptor signaling pathway GO:0008286 40 24 0,000 0,01905622 0,02730798 ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,01905622 0,02729098 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,01905622 0,027274 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,01905622 0,02725704 ! vacuole organization GO:0007033 39 24 0,000 0,01905622 0,0272401 ! receptor metabolic process GO:0043112 37 24 0,000 0,01905622 0,02722318 ! neural crest cell development GO:0014032 39 24 0,000 0,01905622 0,02720628 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,01905622 0,0271894 ! primary neural tube formation GO:0014020 35 24 0,000 0,01905622 0,02717254 ! negative regulation of cell development GO:0010721 56 24 0,000 0,01905622 0,02715571 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,01905622 0,02713889 ! base-excision repair GO:0006284 31 24 0,000 0,01905622 0,0271221 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,01905622 0,02710533 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,01905622 0,02708857 ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,01905622 0,02707184 ! glutathione metabolic process GO:0006749 29 24 0,000 0,01905622 0,02705513 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,01905622 0,02703844 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,01905622 0,02702177 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,01905622 0,02700512 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,01984287 0,02810258 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,01984287 0,02808529 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,01984287 0,02806802 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,01984287 0,02805076 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,01984287 0,02803353 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,01984287 0,02801632 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 0,000 0,01984287 0,02799914 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,01984287 0,02798197 ! peptide transport GO:0015833 43 25 0,000 0,01984287 0,02796482 ! male gonad development GO:0008584 33 25 0,000 0,01984287 0,0279477 ! iron ion homeostasis GO:0055072 39 25 0,000 0,01984287 0,0279306 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,01984287 0,02791351 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,01984287 0,02789645 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,01984287 0,02787941 ! phospholipid transport GO:0015914 35 25 0,000 0,01984287 0,02786239 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,01984287 0,02784539 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,01984287 0,02782841 ! detection of light stimulus GO:0009583 30 25 0,000 0,01984287 0,02781145 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,01984287 0,02779451 GO:0045840|positive regulation of mitosis, ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,01984287 0,0277776 ! leukocyte proliferation GO:0070661 39 25 0,000 0,01984287 0,0277607 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,01984287 0,02774383 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,02062892 0,02882535 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,02062892 0,02880785 ! translational initiation GO:0006413 43 26 0,000 0,02062892 0,02879037 ! regulation of pH GO:0006885 36 26 0,000 0,02062892 0,02877291 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 0,000 0,02062892 0,02875547 ! circadian rhythm GO:0007623 42 26 0,000 0,02062892 0,02873805 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,02062892 0,02872066 ! post-embryonic development GO:0009791 42 26 0,000 0,02062892 0,02870328 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,02062892 0,02868593 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,02062892 0,02866859 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,02062892 0,02865128 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,02062892 0,02863399 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,02062892 0,02861672 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,02062892 0,02859947 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,02062892 0,02858224 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,02062892 0,02856504 ! regulation of coagulation GO:0050818 39 26 0,000 0,02062892 0,02854785 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,0214144 0,02961702 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,0214144 0,02959922 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,0214144 0,02958145 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,0214144 0,02956369 ! membrane docking GO:0022406 39 27 0,000 0,0214144 0,02954596 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,0214144 0,02952824 ! catechol metabolic process GO:0009712 43 27 0,000 0,0214144 0,02951055 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,0214144 0,02949288 ! acute-phase response GO:0006953 42 27 0,000 0,0214144 0,02947523 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,0214144 0,0294576 ! myofibril assembly GO:0030239 36 27 0,000 0,0214144 0,02943999 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,0214144 0,02942241 ! response to ionizing radiation GO:0010212 47 27 0,000 0,0214144 0,02940484 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,0214144 0,0293873 ! natural killer cell activation GO:0030101 35 27 0,000 0,0214144 0,02936977 ! lipid oxidation GO:0034440 38 27 0,000 0,0214144 0,02935227 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,0214144 0,02933479 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,0214144 0,02931733 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,0214144 0,02929989 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,0214144 0,02928247 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,0214144 0,02926507 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,0214144 0,02924769 ! gene silencing GO:0016458 41 27 0,000 0,0214144 0,02923033 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,02219928 0,03028372 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,02219928 0,03026577 ! phenol metabolic process GO:0018958 44 28 0,000 0,02219928 0,03024784 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,02219928 0,03022993 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,02219928 0,03021204 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,02219928 0,03019417 ! cell junction assembly GO:0034329 56 28 0,000 0,02219928 0,03017633 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,02219928 0,0301585 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,02219928 0,0301407 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,02219928 0,03012292 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,02219928 0,03010516 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,02219928 0,03008742 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,02219928 0,0300697 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,02219928 0,030052 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,02219928 0,03003432 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,02219928 0,03001667 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,02219928 0,02999903 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,02219928 0,02998141 ! mesoderm formation GO:0001707 46 28 0,000 0,02219928 0,02996382 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,02219928 0,02994625 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,02219928 0,02992869 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,02219928 0,02991116 ! ensheathment of neurons GO:0007272 43 28 0,000 0,02219928 0,02989365 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,02219928 0,02987615 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,02219928 0,02985868 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,02219928 0,02984123 ! neural tube formation GO:0001841 41 28 0,000 0,02219928 0,0298238 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,02219928 0,02980639 ! placenta development GO:0001890 37 28 0,000 0,02219928 0,029789 ! regulation of B cell activation GO:0050864 42 28 0,000 0,02219928 0,02977163 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,02298358 0,0308055 ! regulation of innate immune response GO:0045088 38 29 0,000 0,02298358 0,03078756 ! ovulation cycle process GO:0022602 41 29 0,000 0,02298358 0,03076964 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,02298358 0,03075174 ! protein targeting to membrane GO:0006612 53 29 0,000 0,02298358 0,03073386 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,02298358 0,030716 ! mismatch repair GO:0006298 34 29 0,000 0,02298358 0,03069817 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,02298358 0,03068035 ! muscle cell development GO:0055001 38 29 0,000 0,02298358 0,03066255 ! formation of primary germ layer GO:0001704 48 29 0,000 0,02298358 0,03064478 ! telencephalon development GO:0021537 52 29 0,000 0,02298358 0,03062702 ! eye morphogenesis GO:0048592 51 29 0,000 0,02298358 0,03060929 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,02298358 0,03059158 ! tissue homeostasis GO:0001894 42 29 0,000 0,02298358 0,03057388 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,0237673 0,03159815 ! collagen metabolic process GO:0032963 40 30 0,000 0,0237673 0,03157989 ! organic anion transport GO:0015711 51 30 0,000 0,0237673 0,03156166 ! cholesterol transport GO:0030301 46 30 0,000 0,0237673 0,03154345 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,0237673 0,03152526 ! spliceosome assembly GO:0000245 49 30 0,000 0,0237673 0,03150709 ! spindle organization GO:0007051 37 30 0,000 0,0237673 0,03148894 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,0237673 0,03147081 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,0237673 0,0314527 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,0237673 0,03143461 ! ceramide metabolic process GO:0006672 43 30 0,000 0,0237673 0,03141655 ! ovulation cycle GO:0042698 43 30 0,000 0,0237673 0,0313985 ! hindbrain development GO:0030902 45 30 0,000 0,0237673 0,03138048 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,0237673 0,03136248 ! adult locomotory behavior GO:0008344 47 30 0,000 0,0237673 0,03134449 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,0237673 0,03132653 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,0237673 0,03130859 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,0237673 0,03129067 ! response to heat GO:0009408 41 30 0,000 0,0237673 0,03127277 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,0237673 0,03125489 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,0237673 0,03123703 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,02455044 0,03224786 ! negative regulation of secretion GO:0051048 49 31 0,000 0,02455044 0,03222945 ! mammary gland development GO:0030879 57 31 0,000 0,02455044 0,03221107 ! glial cell differentiation GO:0010001 55 31 0,000 0,02455044 0,0321927 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,02455044 0,03217436 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,02455044 0,03215604 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,02455044 0,03213774 ! odontogenesis GO:0042476 50 31 0,000 0,02455044 0,03211946 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,02455044 0,0321012 ! segmentation GO:0035282 41 31 0,000 0,02455044 0,03208296 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,02455044 0,03206474 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,02455044 0,03204654 ! metanephros development GO:0001656 58 31 0,000 0,02455044 0,03202836 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,02455044 0,03201021 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,02455044 0,03199207 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,02455044 0,03197395 ! cell fate specification GO:0001708 37 31 0,000 0,02455044 0,03195586 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,02455044 0,03193778 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,02455044 0,03191973 ! RNA modification GO:0009451 40 31 0,000 0,02455044 0,0319017 ! regulation of muscle development GO:0048634 48 32 0,000 0,02533299 0,03289998 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,02533299 0,03288142 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,02533299 0,03286287 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,02533299 0,03284435 ! meiosis I GO:0007127 52 32 0,000 0,02533299 0,03282584 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,02533299 0,03280736 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,02533299 0,0327889 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,02533299 0,03277046 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,02533299 0,03275204 ! peripheral nervous system development GO:0007422 53 32 0,000 0,02533299 0,03273364 ! regulation of protein stability GO:0031647 48 32 0,000 0,02533299 0,03271526 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,02533299 0,0326969 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,02533299 0,03267856 ! cytokine production GO:0001816 44 32 0,000 0,02533299 0,03266024 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,02533299 0,03264194 ! vesicle localization GO:0051648 47 32 0,000 0,02533299 0,03262367 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,02611496 0,03361186 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,02611496 0,03359306 ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,02611496 0,03357429 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,02611496 0,03355553 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,02611496 0,03353679 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,02611496 0,03351808 ! sister chromatid segregation GO:0000819 46 33 0,000 0,02611496 0,03349938 ! ear morphogenesis GO:0042471 42 33 0,000 0,02611496 0,03348071 ! actomyosin structure organization GO:0031032 43 33 0,000 0,02611496 0,03346206 ! cell junction organization GO:0034330 63 33 0,000 0,02611496 0,03344343 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,02611496 0,03342482 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,02611496 0,03340623 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,02611496 0,03338766 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 0,000 0,02611496 0,03336911 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,02611496 0,03335058 ! female gonad development GO:0008585 49 33 0,000 0,02611496 0,03333207 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,02611496 0,03331359 ! positive regulation of cell development GO:0010720 54 33 0,000 0,02611496 0,03329512 ! lipid homeostasis GO:0055088 55 33 0,000 0,02611496 0,03327667 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,02611496 0,03325825 ! regulation of proteolysis GO:0030162 50 33 0,000 0,02611496 0,03323984 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,02611496 0,03322146 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,02611496 0,03320309 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,02611496 0,03318475 ! cytokinesis GO:0000910 52 33 0,000 0,02611496 0,03316643 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,02611496 0,03314812 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,02689634 0,03412112 ! mRNA catabolic process GO:0006402 48 34 0,000 0,02689634 0,03410231 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,02689634 0,03408352 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,02689634 0,03406475 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,02689634 0,034046 ! feeding behavior GO:0007631 45 34 0,000 0,02689634 0,03402727 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,02689634 0,03400857 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,02689634 0,03398988 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,02689634 0,03397122 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,02689634 0,03395257 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,02689634 0,03393395 ! neuron migration GO:0001764 46 34 0,000 0,02689634 0,03391534 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,02689634 0,03389676 ! female gamete generation GO:0007292 43 34 0,000 0,02689634 0,03387819 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,02689634 0,03385965 ! aerobic respiration GO:0009060 47 34 0,000 0,02689634 0,03384113 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,02689634 0,03382263 ! cellular response to insulin stimulus GO:0032869 52 34 0,000 0,02689634 0,03380414 ! embryonic organ development GO:0048568 45 34 0,000 0,02689634 0,03378568 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,02689634 0,03376724 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,02767714 0,03472855 ! Notch signaling pathway GO:0007219 56 35 0,000 0,02767714 0,03470961 ! regulation of intracellular protein transport GO:0033157 59 35 0,000 0,02767714 0,0346907 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,02767714 0,0346718 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,02767714 0,03465293 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,02767714 0,03463407 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,02767714 0,03461524 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,02767714 0,03459643 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,02767714 0,03457764 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,02767714 0,03455887 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,02767714 0,03454011 ! glycogen metabolic process GO:0005977 48 35 0,000 0,02767714 0,03452138 ! pigment metabolic process GO:0042440 61 35 0,000 0,02767714 0,03450267 ! positive regulation of leukocyte proliferation GO:0070665 50 35 0,000 0,02767714 0,03448398 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! protein homooligomerization GO:0051260 52 35 0,000 0,02767714 0,03446531 ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,02845736 0,03541772 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 0,000 0,02845736 0,03539856 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,02845736 0,03537943 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,02845736 0,03536031 ! negative regulation of binding GO:0051100 58 36 0,000 0,02845736 0,03534122 ! organic ether metabolic process GO:0018904 46 36 0,000 0,02845736 0,03532215 ! tissue remodeling GO:0048771 62 36 0,000 0,02845736 0,0353031 ! neural tube development GO:0021915 50 36 0,000 0,02845736 0,03528406 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,02845736 0,03526505 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,02845736 0,03524606 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,02845736 0,03522709 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,02845736 0,03520814 ! glucan metabolic process GO:0044042 49 36 0,000 0,02845736 0,03518921 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,029237 0,03613386 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,029237 0,03611445 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,029237 0,03609507 ! learning GO:0007612 67 37 0,000 0,029237 0,0360757 ! ion transmembrane transport GO:0034220 56 37 0,000 0,029237 0,03605636 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,029237 0,03603704 ! regulation of protein secretion GO:0050708 51 37 0,000 0,029237 0,03601773 ! amino acid activation GO:0043038 52 37 0,000 0,029237 0,03599845 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,029237 0,03597919 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,03001606 0,03691815 ! gliogenesis GO:0042063 71 38 0,000 0,03001606 0,03689842 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,03001606 0,03687871 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,03001606 0,03685902 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,03001606 0,03683935 ! phagocytosis GO:0006909 60 38 0,000 0,03001606 0,0368197 ! mesenchymal cell development GO:0014031 64 38 0,000 0,03001606 0,03680008 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 0,000 0,03001606 0,03678047 ! maintenance of location in cell GO:0051651 69 38 0,000 0,03001606 0,03676089 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,03079454 0,03769422 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,03079454 0,03767417 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,03079454 0,03765414 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,03079454 0,03763414 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,03079454 0,03761415 ! regulation of epithelial cell proliferation GO:0050678 71 39 0,000 0,03079454 0,03759419 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,03079454 0,03757424 ! male sex differentiation GO:0046661 53 39 0,000 0,03079454 0,03755432 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,03079454 0,03753442 ! chromatin remodeling GO:0006338 68 39 0,000 0,03079454 0,03751454 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,03079454 0,03749468 ! JNK cascade GO:0007254 54 39 0,000 0,03079454 0,03747484 ! developmental growth GO:0048589 62 39 0,000 0,03079454 0,03745502 ! cell growth GO:0016049 61 39 0,000 0,03079454 0,03743522 ! synapse organization GO:0050808 55 39 0,000 0,03079454 0,03741545 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,03157244 0,03834034 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,03157244 0,03832011 ! regulation of tube size GO:0035150 60 40 0,000 0,03157244 0,0382999 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,03157244 0,03827971 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,03157244 0,03825954 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,03157244 0,0382394 ! peptide metabolic process GO:0006518 56 40 0,000 0,03157244 0,03821927 ! induction of apoptosis by intracellular signals GO:0008629 67 40 0,000 0,03157244 0,03819916 ! inner ear development GO:0048839 57 40 0,000 0,03157244 0,03817908 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,03157244 0,03815902 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,03157244 0,03813898 ! double-strand break repair GO:0006302 67 40 0,000 0,03157244 0,03811896 ! B cell differentiation GO:0030183 62 40 0,000 0,03157244 0,03809896 ! epidermal cell differentiation GO:0009913 53 40 0,000 0,03157244 0,03807898 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,03157244 0,03805902 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,03157244 0,03803908 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,03157244 0,03801917 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,03234976 0,03893482 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,03234976 0,03891446 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,03234976 0,03889412 ! glucose transport GO:0015758 52 41 0,000 0,03234976 0,03887379 ! endosome transport GO:0016197 71 41 0,000 0,03234976 0,0388535 ! striated muscle contraction GO:0006941 62 41 0,000 0,03234976 0,03883322 ! positive regulation of DNA binding GO:0043388 57 41 0,000 0,03234976 0,03881296 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,03234976 0,03879272 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,03234976 0,03877251 ! biopolymer methylation GO:0043414 62 41 0,000 0,03234976 0,03875231 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,03234976 0,03873214 ! mitochondrial transport GO:0006839 60 42 0,000 0,0331265 0,03964149 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,0331265 0,03962088 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 0,000 0,0331265 0,03960028 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,0331265 0,03957971 ! cellular component disassembly GO:0022411 64 42 0,000 0,0331265 0,03955916 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,0331265 0,03953863 ! hexose transport GO:0008645 54 42 0,000 0,0331265 0,03951812 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,0331265 0,03949764 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,0331265 0,03947717 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,0331265 0,03945673 ! excretion GO:0007588 63 42 0,000 0,0331265 0,03943631 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,0331265 0,0394159 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,0331265 0,03939552 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,0331265 0,03937516 ! regulation of cell shape GO:0008360 78 42 0,000 0,0331265 0,03935483 ! positive regulation of binding GO:0051099 59 43 0,000 0,03390266 0,04025612 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,03390266 0,04023535 ! leukocyte migration GO:0050900 60 43 0,000 0,03390266 0,0402146 ! neuromuscular process GO:0050905 79 43 0,000 0,03390266 0,04019387 ! activation of caspase activity GO:0006919 65 43 0,000 0,03390266 0,04017316 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,03390266 0,04015248 ! tRNA processing GO:0008033 49 43 0,000 0,03390266 0,04013181 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,03390266 0,04011117 ! vesicle organization GO:0016050 79 43 0,000 0,03390266 0,04009055 ! response to insulin stimulus GO:0032868 63 43 0,000 0,03390266 0,04006994 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,03390266 0,04004936 ! methylation GO:0032259 64 43 0,000 0,03390266 0,0400288 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,03467824 0,04092352 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,03467824 0,04090254 ! glycolysis GO:0006096 53 44 0,000 0,03467824 0,04088157 ! regulation of action potential GO:0001508 71 44 0,000 0,03467824 0,04086063 ! regulation of ion transport GO:0043269 57 44 0,000 0,03467824 0,04083971 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,03467824 0,04081881 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,03467824 0,04079793 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,03467824 0,04077707 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,03467824 0,04075623 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,03467824 0,04073542 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,03467824 0,04071462 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,03467824 0,04069385 ! regulation of mast cell proliferation GO:0070666 64 44 0,000 0,03467824 0,0406731 ! RNA catabolic process GO:0006401 64 45 0,000 0,03545324 0,04156088 ! positive regulation of defense response GO:0031349 59 45 0,000 0,03545324 0,04153971 ! regulation of translational initiation GO:0006446 64 45 0,000 0,03545324 0,04151856 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,03545324 0,04149743 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,03545324 0,04147632 ! cell recognition GO:0008037 58 45 0,000 0,03545324 0,04145524 ! cell maturation GO:0048469 60 45 0,000 0,03545324 0,04143417 ! protein amino acid autophosphorylation GO:0046777 80 45 0,000 0,03545324 0,04141313 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,03622767 0,04229626 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,03622767 0,0422748 ! cell redox homeostasis GO:0045454 63 46 0,000 0,03622767 0,04225336 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,03622767 0,04223195 ! regulation of ossification GO:0030278 71 46 0,000 0,03622767 0,04221055 ! histone modification GO:0016570 68 46 0,000 0,03622767 0,04218918 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,03622767 0,04216783 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,03700151 0,04304678 ! viral infectious cycle GO:0019058 71 47 0,000 0,03700151 0,04302502 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,03700151 0,04300328 ! endocrine system development GO:0035270 83 47 0,000 0,03700151 0,04298156 ! covalent chromatin modification GO:0016569 75 47 0,000 0,03700151 0,04295986 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,03700151 0,04293819 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,03700151 0,04291653 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,03700151 0,0428949 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,03700151 0,04287329 ! regulation of leukocyte proliferation GO:0070663 71 47 0,000 0,03700151 0,0428517 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,03700151 0,04283014 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,03700151 0,04280859 ! chloride transport GO:0006821 67 48 0,000 0,03777479 0,04368125 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,03777479 0,0436593 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 0,000 0,03777479 0,04363737 ! response to temperature stimulus GO:0009266 62 48 0,000 0,03777479 0,04361547 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,03777479 0,04359358 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,03777479 0,04357172 ! gastrulation GO:0007369 73 48 0,000 0,03777479 0,04354988 ! heart morphogenesis GO:0003007 65 48 0,000 0,03777479 0,04352806 ! regulation of DNA replication GO:0006275 75 48 0,000 0,03777479 0,04350626 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,03777479 0,04348449 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,03777479 0,04346273 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,03777479 0,043441 ! regulation of endocytosis GO:0030100 63 48 0,000 0,03777479 0,04341929 ! nuclear export GO:0051168 69 48 0,000 0,03777479 0,04339761 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,03777479 0,04337594 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,03777479 0,04335429 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,03854748 0,04421905 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,03854748 0,04419701 ! sensory perception of smell GO:0007608 61 49 0,000 0,03854748 0,04417499 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,03854748 0,04415299 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,03854748 0,04413101 ! RNA elongation GO:0006354 62 49 0,000 0,03854748 0,04410906 ! regulation of intracellular transport GO:0032386 78 49 0,000 0,03854748 0,04408712 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,03854748 0,04406521 ! germ cell development GO:0007281 68 49 0,000 0,03854748 0,04404332 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,03854748 0,04402145 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,03854748 0,0439996 ! cartilage development GO:0051216 70 49 0,000 0,03854748 0,04397778 ! maintenance of location GO:0051235 84 49 0,000 0,03854748 0,04395598 ! regulation of actin filament length GO:0030832 72 50 0,000 0,0393196 0,04481421 ! ear development GO:0043583 72 50 0,000 0,0393196 0,04479201 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,0393196 0,04476984 ! membrane fusion GO:0006944 80 50 0,000 0,0393196 0,04474769 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,0393196 0,04472556 ! lipid modification GO:0030258 73 50 0,000 0,0393196 0,04470345 ! positive regulation of growth GO:0045927 67 50 0,000 0,0393196 0,04468136 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,0393196 0,0446593 ! proton transport GO:0015992 75 50 0,000 0,0393196 0,04463725 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,0393196 0,04461523 ! positive regulation of secretion GO:0051047 71 51 0,000 0,04009114 0,04546826 ! hydrogen transport GO:0006818 77 51 0,000 0,04009114 0,04544585 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,04009114 0,04542346 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 0,000 0,04009114 0,04540109 ! positive regulation of cell migration GO:0030335 92 51 0,000 0,04009114 0,04537875 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,04009114 0,04535643 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,04009114 0,04533413 ! adult behavior GO:0030534 80 51 0,000 0,04009114 0,04531185 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,04009114 0,0452896 ! transition metal ion transport GO:0000041 74 52 0,000 0,04086211 0,04613787 ! regulation of cellular component size GO:0032535 74 52 0,000 0,04086211 0,04611523 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,04086211 0,04609262 ! aging GO:0007568 79 52 0,000 0,04086211 0,04607002 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,04086211 0,04604745 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,04086211 0,0460249 ! establishment of organelle localization GO:0051656 85 52 0,000 0,04086211 0,04600237 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,0416325 0,04684675 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,0416325 0,04682384 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,0416325 0,04680095 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,0416325 0,04677809 ! kidney development GO:0001822 90 53 0,000 0,0416325 0,04675525 ! single fertilization GO:0007338 59 53 0,000 0,0416325 0,04673243 ! cell projection assembly GO:0030031 76 53 0,000 0,0416325 0,04670963 ! amino acid transport GO:0006865 84 54 0,000 0,04240232 0,04755014 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,04240232 0,04752696 ! regulation of mitosis GO:0007088 84 54 0,000 0,04240232 0,04750381 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,04240232 0,04748069 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,04240232 0,04745758 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,04240232 0,0474345 ! DNA catabolic process GO:0006308 67 54 0,000 0,04240232 0,04741144 ! detection of external stimulus GO:0009581 66 54 0,000 0,04240232 0,0473884 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,04240232 0,04736538 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,04240232 0,04734239 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,04240232 0,04731942 ! exocytosis GO:0006887 74 55 0,000 0,04317156 0,0481545 ! mesoderm development GO:0007498 76 55 0,000 0,04317156 0,04813116 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,04317156 0,04810784 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,04317156 0,04808455 ! DNA damage response, signal transduction GO:0042770 96 56 0,000 0,04394023 0,048917 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,04394023 0,04889334 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,04394023 0,04886969 ! positive regulation of cell motion GO:0051272 99 56 0,000 0,04394023 0,04884607 ! negative regulation of protein kinase activity GO:0006469 99 57 0,000 0,04470832 0,04967592 ! carbohydrate transport GO:0008643 74 57 0,000 0,04470832 0,04965193 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,04470832 0,04962797 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 0,000 0,04470832 0,04960403 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,04470832 0,04958011 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,04470832 0,04955621 ! camera-type eye development GO:0043010 88 57 0,000 0,04470832 0,04953234 ! secondary metabolic process GO:0019748 84 57 0,000 0,04470832 0,0495085 ! response to peptide hormone stimulus GO:0043434 84 57 0,000 0,04470832 0,04948467 ! developmental maturation GO:0021700 75 57 0,000 0,04470832 0,04946087 ! gonad development GO:0008406 79 57 0,000 0,04470832 0,04943709 ! negative regulation of kinase activity GO:0033673 100 58 0,000 0,04547585 0,05026163 ! viral reproductive process GO:0022415 87 58 0,000 0,04547585 0,05023749 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,04547585 0,05021337 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,04547585 0,05018927 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,04547585 0,0501652 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,0462428 0,05098678 ! activation of MAPK activity GO:0000187 84 59 0,000 0,0462428 0,05096235 ! lung development GO:0030324 94 59 0,000 0,0462428 0,05093795 ! actin filament organization GO:0007015 95 59 0,000 0,0462428 0,05091356 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,0462428 0,0508892 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,0462428 0,05086487 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,04700917 0,05168313 ! phosphoinositide metabolic process GO:0030384 87 60 0,000 0,04700917 0,05165843 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,04700917 0,05163376 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,04700917 0,05160912 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,04700917 0,0515845 ! regulation of heart contraction GO:0008016 91 60 0,000 0,04700917 0,0515599 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,04700917 0,05153532 ! fertilization GO:0009566 68 60 0,000 0,04700917 0,05151077 ! regulation of homeostatic process GO:0032844 105 60 0,000 0,04700917 0,05148624 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,04777498 0,05230007 ! meiosis GO:0007126 96 61 0,000 0,04777498 0,05227519 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 114 61 0,000 0,04777498 0,05225034 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,04777498 0,0522255 ! urogenital system development GO:0001655 101 61 0,000 0,04777498 0,05220069 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,04777498 0,05217591 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,04777498 0,05215114 ! extracellular matrix organization GO:0030198 103 61 0,000 0,04777498 0,0521264 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,04777498 0,05210169 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! negative regulation of transferase activity GO:0051348 105 61 0,000 0,04777498 0,05207699 ! amine catabolic process GO:0009310 90 62 0,000 0,04854022 0,05288607 ! neurotransmitter transport GO:0006836 81 62 0,000 0,04854022 0,05286103 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,04854022 0,05283601 ! negative regulation of cell growth GO:0030308 106 62 0,000 0,04854022 0,05281102 ! respiratory tube development GO:0030323 99 62 0,000 0,04854022 0,05278605 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,04854022 0,0527611 ! meiotic cell cycle GO:0051321 97 62 0,000 0,04854022 0,05273618 ! organelle localization GO:0051640 96 62 0,000 0,04854022 0,05271128 ! regulation of transcription factor activity GO:0051090 97 63 0,000 0,04930488 0,05351639 GO:0090046|regulation of transcription regulator activity, ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,04930488 0,05349114 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 0,000 0,04930488 0,05346592 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 0,000 0,04930488 0,05344073 ! viral reproduction GO:0016032 92 63 0,000 0,04930488 0,05341555 ! regulation of lipase activity GO:0060191 109 63 0,000 0,04930488 0,05339041 ! cell cycle checkpoint GO:0000075 108 64 0,000 0,05006897 0,0541923 ! negative regulation of cell size GO:0045792 108 64 0,000 0,05006897 0,05416681 ! appendage morphogenesis GO:0035107 93 64 0,000 0,05006897 0,05414134 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,05006897 0,0541159 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,05006897 0,05409048 ! hexose catabolic process GO:0019320 82 64 0,000 0,05006897 0,05406509 ! respiratory system development GO:0060541 100 64 0,000 0,05006897 0,05403972 ! adaptive immune response GO:0002250 94 64 0,000 0,05006897 0,05401437 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 90 65 0,000 0,05083249 0,05481235 ! regulation of caspase activity GO:0043281 97 65 0,000 0,05083249 0,05478666 ! appendage development GO:0048736 94 65 0,000 0,05083249 0,054761 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 0,000 0,05083249 0,05473536 ! defense response to bacterium GO:0042742 73 65 0,000 0,05083249 0,05470975 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,05083249 0,05468416 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,05083249 0,0546586 ! activation of immune response GO:0002253 83 65 0,000 0,05083249 0,05463305 ! protein oligomerization GO:0051259 100 65 0,000 0,05083249 0,05460754 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,05159545 0,05540127 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,05159545 0,05537542 ! antigen processing and presentation GO:0019882 96 66 0,000 0,05159545 0,05534959 ! axon guidance GO:0007411 99 66 0,000 0,05159545 0,05532379 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,05159545 0,05529801 ! regulation of immune effector process GO:0002697 101 66 0,000 0,05159545 0,05527225 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,05235783 0,05606285 ! regulation of endopeptidase activity GO:0052548 99 67 0,000 0,05235783 0,05603677 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,05235783 0,0560107 ! acute inflammatory response GO:0002526 92 68 0,000 0,05311964 0,05679925 ! learning or memory GO:0007611 123 68 0,000 0,05311964 0,05677285 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,05311964 0,05674648 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,05311964 0,05672014 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,05311964 0,05669382 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,05311964 0,05666752 ! rhythmic process GO:0048511 105 68 0,000 0,05311964 0,05664125 ! inorganic anion transport GO:0015698 93 68 0,000 0,05311964 0,056615 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,05388089 0,05739974 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,05388089 0,05737317 ! response to drug GO:0042493 108 69 0,000 0,05388089 0,05734662 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,05464157 0,05812933 ! humoral immune response GO:0006959 86 70 0,000 0,05464157 0,05810245 ! eye development GO:0001654 111 70 0,000 0,05464157 0,0580756 ! amine transport GO:0015837 101 70 0,000 0,05464157 0,05804878 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,05464157 0,05802198 ! regulation of catabolic process GO:0009894 106 70 0,000 0,05464157 0,0579952 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,05540167 0,05877484 ! muscle cell differentiation GO:0042692 104 71 0,000 0,05540167 0,05874774 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,05540167 0,05872067 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,05540167 0,05869362 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,05540167 0,0586666 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,05540167 0,0586396 ! regulation of peptidase activity GO:0052547 106 72 0,000 0,05616122 0,05941619 ! response to hypoxia GO:0001666 132 72 0,000 0,05616122 0,05938887 ! negative regulation of organelle organization GO:0010639 115 72 0,000 0,05616122 0,05936158 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,05616122 0,05933431 ! negative regulation of transport GO:0051051 116 73 0,000 0,05692019 0,06010856 ! regulation of blood pressure GO:0008217 107 73 0,000 0,05692019 0,06008097 ! tube morphogenesis GO:0035239 118 73 0,000 0,05692019 0,06005341 ! mitochondrion organization GO:0007005 104 73 0,000 0,05692019 0,06002588 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,05692019 0,05999837 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,05692019 0,05997088 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,0576786 0,06074211 ! response to oxygen levels GO:0070482 137 74 0,000 0,0576786 0,06071431 ! digestion GO:0007586 97 74 0,000 0,0576786 0,06068654 ! protein import into nucleus GO:0006606 118 74 0,000 0,0576786 0,06065879 ! cellular response to hormone stimulus GO:0032870 109 74 0,000 0,0576786 0,06063107 ! positive regulation of lymphocyte activation GO:0051251 108 74 0,000 0,0576786 0,06060337 ! blood coagulation GO:0007596 116 75 0,000 0,05843644 0,0613716 GO:0050817|coagulation, ! negative regulation of growth GO:0045926 123 75 0,000 0,05843644 0,06134359 ! response to nutrient GO:0007584 104 75 0,000 0,05843644 0,06131561 ! nuclear import GO:0051170 121 75 0,000 0,05843644 0,06128765 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,05843644 0,06125971 ! amine biosynthetic process GO:0009309 97 76 0,000 0,05919371 0,0620253 ! tRNA metabolic process GO:0006399 95 76 0,000 0,05919371 0,06199706 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,05919371 0,06196884 ! regulation of protein transport GO:0051223 114 76 0,000 0,05919371 0,06194065 GO:0070201|regulation of establishment of protein localization, ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,05995042 0,06270395 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,05995042 0,06267544 ! regulation of DNA binding GO:0051101 119 77 0,000 0,05995042 0,06264697 ! gland development GO:0048732 148 77 0,000 0,05995042 0,06261852 ! sex differentiation GO:0007548 105 77 0,000 0,05995042 0,06259009 ! protein ubiquitination GO:0016567 125 77 0,000 0,05995042 0,0625617 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,05995042 0,06253332 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,05995042 0,06250498 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,06070657 0,06326466 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,06070657 0,06323601 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,06146215 0,06399409 ! cellular respiration GO:0045333 107 79 0,000 0,06146215 0,06396513 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,06146215 0,0639362 ! T cell activation GO:0042110 134 79 0,000 0,06146215 0,0639073 ! regulation of lyase activity GO:0051339 133 79 0,000 0,06146215 0,06387842 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,06146215 0,06384957 ! chromatin assembly GO:0031497 102 80 0,000 0,06221716 0,06460473 GO:0006334|nucleosome assembly, ! protein localization in nucleus GO:0034504 133 80 0,000 0,06221716 0,06457558 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,06221716 0,06454645 ! forebrain development GO:0030900 131 80 0,000 0,06221716 0,06451735 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,06297161 0,06527026 ! hemostasis GO:0007599 125 81 0,000 0,06297161 0,06524086 ! mRNA transport GO:0051028 121 81 0,000 0,06297161 0,06521149 ! regulation of cell cycle process GO:0010564 122 81 0,000 0,06297161 0,06518214 ! regulation of neurological system process GO:0031644 122 81 0,000 0,06297161 0,06515282 ! vitamin metabolic process GO:0006766 103 81 0,000 0,06297161 0,06512352 ! positive regulation of cell activation GO:0050867 120 81 0,000 0,06297161 0,06509425 GO:0002696|positive regulation of leukocyte activation, ! ossification GO:0001503 134 82 0,000 0,0637255 0,06584396 GO:0060348|bone development, ! detection of stimulus GO:0051606 108 82 0,000 0,0637255 0,06581439 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,06447883 0,06656252 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,06447883 0,06653266 ! regulation of cell adhesion GO:0030155 159 83 0,000 0,06447883 0,06650283 ! regulation of defense response GO:0031347 117 84 0,000 0,06523159 0,06724906 ! microtubule cytoskeleton organization GO:0000226 120 84 0,000 0,06523159 0,06721893 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,06523159 0,06718883 ! sterol metabolic process GO:0016125 120 84 0,000 0,06523159 0,06715875 ! regulation of DNA metabolic process GO:0051052 135 85 0,000 0,06598379 0,06790278 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,06598379 0,06787241 ! rRNA metabolic process GO:0016072 107 85 0,000 0,06598379 0,06784207 GO:0006364|rRNA processing, ! positive regulation of MAP kinase activity GO:0043406 121 85 0,000 0,06598379 0,06781176 ! transcription initiation GO:0006352 118 85 0,000 0,06598379 0,06778147 ! anterior/posterior pattern formation GO:0009952 124 85 0,000 0,06598379 0,06775121 ! regulation of protein localization GO:0032880 132 85 0,000 0,06598379 0,06772098 ! regulation of membrane potential GO:0042391 128 85 0,000 0,06598379 0,06769077 ! negative regulation of multicellular organismal process GO:0051241 133 85 0,000 0,06598379 0,06766059 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,06673542 0,06840084 ! nucleosome organization GO:0034728 114 87 0,000 0,0674865 0,06913984 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,0674865 0,06910906 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,0674865 0,0690783 ! skeletal muscle tissue development GO:0007519 123 87 0,000 0,0674865 0,06904757 GO:0060538|skeletal muscle organ development, ! female pregnancy GO:0007565 130 87 0,000 0,0674865 0,06901687 ! Wnt receptor signaling pathway GO:0016055 130 87 0,000 0,0674865 0,0689862 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,06823701 0,0697224 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,06823701 0,06969144 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,06823701 0,06966051 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,06823701 0,06962961 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 0,000 0,06823701 0,06959873 ! regulation of neurogenesis GO:0050767 153 89 0,000 0,06898697 0,07033246 ! reproductive developmental process GO:0003006 127 89 0,000 0,06898697 0,07030129 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,06898697 0,07027016 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,06898697 0,07023905 ! regulation of T cell activation GO:0050863 128 89 0,000 0,06898697 0,07020797 ! leukocyte differentiation GO:0002521 143 90 0,000 0,06973636 0,07093924 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,06973636 0,07090788 ! hormone metabolic process GO:0042445 121 90 0,000 0,06973636 0,07087655 ! RNA localization GO:0006403 135 91 0,000 0,07048519 0,07160598 ! ATP metabolic process GO:0046034 137 91 0,000 0,07048519 0,07157437 ! response to virus GO:0009615 122 91 0,000 0,07048519 0,07154278 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,07123346 0,07227039 ! glycerophospholipid metabolic process GO:0006650 130 92 0,000 0,07123346 0,07223852 ! cell fate commitment GO:0045165 141 92 0,000 0,07123346 0,07220668 ! positive regulation of immune response GO:0050778 121 92 0,000 0,07123346 0,07217487 ! DNA recombination GO:0006310 146 92 0,000 0,07123346 0,07214309 ! sulfur metabolic process GO:0006790 118 92 0,000 0,07123346 0,07211134 ! regulation of cytoskeleton organization GO:0051493 154 93 0,000 0,07198118 0,07283621 ! peptidyl-amino acid modification GO:0018193 147 93 0,000 0,07198118 0,07280418 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,07198118 0,07277218 ! electron transport chain GO:0022900 123 94 0,000 0,07272833 0,07349524 ! response to oxidative stress GO:0006979 141 94 0,000 0,07272833 0,07346296 ! regulation of binding GO:0051098 151 95 0,000 0,07347493 0,07418452 ! angiogenesis GO:0001525 149 95 0,000 0,07347493 0,07415197 ! carboxylic acid transport GO:0046942 147 95 0,000 0,07347493 0,07411944 GO:0015849|organic acid transport, ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,07422096 0,0748392 ! in utero embryonic development GO:0001701 147 96 0,000 0,07422096 0,0748064 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,07422096 0,07477364 ! regulation of cellular component biogenesis GO:0044087 158 96 0,000 0,07422096 0,0747409 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,07422096 0,07470819 ! protein maturation GO:0051604 129 96 0,000 0,07422096 0,07467551 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,07496644 0,07539257 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,07496644 0,07535962 ! calcium ion transport GO:0006816 167 99 0,000 0,07645573 0,07682314 ! extracellular structure organization GO:0043062 156 99 0,000 0,07645573 0,0767896 ! protein import GO:0017038 156 99 0,000 0,07645573 0,07675608 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 0,000 0,07645573 0,07672259 ! regulation of translation GO:0006417 151 100 0,000 0,07719954 0,07743521 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,07719954 0,07740146 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,07719954 0,07736773 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,07719954 0,07733403 ! divalent metal ion transport GO:0070838 171 100 0,000 0,07719954 0,07730036 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,07719954 0,07726673 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,07719954 0,07723312 ! protein localization in organelle GO:0033365 161 100 0,000 0,07719954 0,07719954