pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-b2/out-0.05-06-0.01-300-run-b2//th1-pval-1e-01-06-th2-pval-1e-02-02-th3-pval-1e-01-01-run-b2/go_data/5203-6-real-Schmidt-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! spindle assembly GO:0051225 5 5 3,000 1,286E-12 2,958E-09 ! natural killer cell mediated immunity GO:0002228 13 9 3,000 3,234E-11 3,72E-08 GO:0042267|natural killer cell mediated cytotoxicity, ! leukocyte mediated cytotoxicity GO:0001909 17 11 3,000 8,464E-11 6,489E-08 ! cell killing GO:0001906 20 14 3,000 2,564E-10 1,474E-07 ! microtubule cytoskeleton organization GO:0000226 120 84 4,000 4,393E-09 2,021E-06 ! spindle organization GO:0007051 37 30 3,000 6,968E-09 2,671E-06 ! lymphocyte mediated immunity GO:0002449 88 62 3,000 1,398E-07 4,592E-05 ! leukocyte mediated immunity GO:0002443 99 71 3,000 2,424E-07 6,97E-05 ! regulation of centrosome cycle GO:0046605 7 5 1,000 5,947E-06 1,52E-03 ! positive regulation of protein ubiquitination GO:0031398 8 6 1,000 8,917E-06 2,051E-03 ! positive regulation of DNA repair GO:0045739 7 6 1,000 8,917E-06 1,864E-03 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 1,000 8,917E-06 1,709E-03 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 1,248E-05 2,208E-03 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 1,000 1,248E-05 2,05E-03 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 2,000 1,432E-05 2,195E-03 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 2,000 1,504E-05 2,162E-03 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 1,000 1,663E-05 2,25E-03 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 2,000 1,734E-05 2,216E-03 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 2,000 1,734E-05 2,099E-03 ! positive regulation of ligase activity GO:0051351 99 69 2,000 2,076E-05 2,388E-03 ! postreplication repair GO:0006301 11 9 1,000 2,137E-05 2,341E-03 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 2,000 2,263E-05 2,366E-03 ! regulation of ligase activity GO:0051340 114 75 2,000 2,668E-05 2,668E-03 ! negative regulation of lipid metabolic process GO:0045833 14 10 1,000 2,67E-05 2,559E-03 ! positive regulation of protein modification process GO:0031401 107 78 2,000 3,002E-05 2,762E-03 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 2,000 3,239E-05 2,865E-03 GO:0010498|proteasomal protein catabolic process, ! double-strand break repair via homologous recombination GO:0000724 16 11 1,000 3,262E-05 2,779E-03 GO:0000725|recombinational repair, ! interphase of mitotic cell cycle GO:0051329 156 86 2,000 4,023E-05 3,305E-03 ! interphase GO:0051325 159 88 2,000 4,31E-05 3,418E-03 ! regulation of DNA repair GO:0006282 15 13 1,000 4,622E-05 3,543E-03 ! regulation of lipid biosynthetic process GO:0046890 16 14 1,000 5,39E-05 3,999E-03 ! regulation of protein ubiquitination GO:0031396 19 15 1,000 6,216E-05 4,468E-03 ! negative regulation of cell cycle process GO:0010948 24 15 1,000 6,216E-05 4,332E-03 ! centrosome cycle GO:0007098 16 15 1,000 6,216E-05 4,205E-03 ! cellular response to unfolded protein GO:0034620 19 16 1,000 7,101E-05 4,666E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! regulation of fatty acid metabolic process GO:0019217 28 19 1,000 1,01E-04 6,456E-03 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 1,000 1,24E-04 7,707E-03 ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 1,24E-04 7,504E-03 ! microtubule organizing center organization GO:0031023 28 22 1,000 1,363E-04 8,039E-03 GO:0051297|centrosome organization, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 1,000 1,363E-04 7,838E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 1,000 1,492E-04 8,372E-03 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 1,492E-04 8,172E-03 ! fat cell differentiation GO:0045444 37 24 1,000 1,627E-04 8,704E-03 ! regulation of cellular ketone metabolic process GO:0010565 34 25 1,000 1,768E-04 9,241E-03 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 1,000 1,914E-04 9,785E-03 ! regulation of microtubule-based process GO:0032886 58 30 1,000 2,558E-04 0,01278815 ! positive regulation of DNA metabolic process GO:0051054 54 33 1,000 3,1E-04 0,01517107 ! androgen receptor signaling pathway GO:0030521 54 33 1,000 3,1E-04 0,01485501 ! response to calcium ion GO:0051592 58 40 1,000 4,565E-04 0,0214283 ! induction of apoptosis by intracellular signals GO:0008629 67 40 1,000 4,565E-04 0,02099973 ! double-strand break repair GO:0006302 67 40 1,000 4,565E-04 0,02058797 ! regulation of gene expression, epigenetic GO:0040029 72 42 1,000 5,035E-04 0,02226853 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 1,000 5,278E-04 0,02290367 ! positive regulation of cell cycle GO:0045787 77 45 1,000 5,781E-04 0,02462278 ! response to UV GO:0009411 75 46 1,000 6,041E-04 0,02526241 ! response to estrogen stimulus GO:0043627 74 47 1,000 6,307E-04 0,02590216 ! negative regulation of cytoskeleton organization GO:0051494 84 50 1,000 7,137E-04 0,02879808 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 1,000 7,425E-04 0,02944326 ! DNA damage response, signal transduction GO:0042770 96 56 1,000 8,948E-04 0,03488021 ! regulation of lipid metabolic process GO:0019216 84 56 1,000 8,948E-04 0,03429887 ! chromosome segregation GO:0007059 83 57 1,000 9,269E-04 0,03494739 ! steroid hormone receptor signaling pathway GO:0030518 96 58 1,000 9,595E-04 0,03559543 ! regulation of cellular response to stress GO:0080135 85 61 1,000 1,061E-03 0,03872824 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 1,000 1,131E-03 0,04064828 ! cell cycle checkpoint GO:0000075 108 64 1,000 1,167E-03 0,04129509 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 1,000 1,167E-03 0,04066941 ! response to metal ion GO:0010038 103 70 1,000 1,394E-03 0,04785991 ! positive regulation of phosphorylation GO:0042327 102 70 1,000 1,394E-03 0,04715609 ! steroid biosynthetic process GO:0006694 94 71 1,000 1,434E-03 0,04779784 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 1,000 1,474E-03 0,048439 GO:0045937|positive regulation of phosphate metabolic process, ! negative regulation of organelle organization GO:0010639 115 72 1,000 1,474E-03 0,04775676 ! response to steroid hormone stimulus GO:0048545 114 73 1,000 1,515E-03 0,04839791 ! response to inorganic substance GO:0010035 115 75 1,000 1,598E-03 0,05035895 ! response to unfolded protein GO:0006986 99 76 1,000 1,641E-03 0,05099776 ! regulation of cell cycle process GO:0010564 122 81 1,000 1,861E-03 0,05707275 ! response to protein stimulus GO:0051789 111 81 1,000 1,861E-03 0,05632179 ! regulation of DNA metabolic process GO:0051052 135 85 1,000 2,047E-03 0,0611404 ! DNA recombination GO:0006310 146 92 1,000 2,392E-03 0,07054488 ! regulation of cytoskeleton organization GO:0051493 154 93 1,000 2,444E-03 0,07115019 ! response to light stimulus GO:0009416 153 96 1,000 2,601E-03 0,07478967 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 3,998E-03 0,1135282 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 3,998E-03 0,11214371 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 3,998E-03 0,11079258 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 3,998E-03 0,10947362 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 3,998E-03 0,1081857 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 3,998E-03 0,10692773 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 3,998E-03 0,10569867 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 3,998E-03 0,10449755 ! sleep GO:0030431 11 5 0,000 3,998E-03 0,10332342 ! negative regulation of bone resorption GO:0045779 10 5 0,000 3,998E-03 0,10217538 ! nucleotide-sugar transport GO:0015780 8 5 0,000 3,998E-03 0,10105258 ! regulation of interferon-beta production GO:0032648 5 5 0,000 3,998E-03 0,09995418 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 3,998E-03 0,0988794 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 3,998E-03 0,09782749 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 3,998E-03 0,09679773 ! tongue development GO:0043586 6 5 0,000 3,998E-03 0,09578942 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 3,998E-03 0,0948019 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 3,998E-03 0,09383454 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 3,998E-03 0,09288671 ! cobalt ion transport GO:0006824 9 5 0,000 3,998E-03 0,09195784 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 3,998E-03 0,09104737 ! SMAD protein complex assembly GO:0007183 9 5 0,000 3,998E-03 0,09015475 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 3,998E-03 0,08927946 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 3,998E-03 0,088421 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 3,998E-03 0,0875789 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 3,998E-03 0,08675268 ! embryonic camera-type eye development GO:0031076 8 5 0,000 3,998E-03 0,08594191 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 3,998E-03 0,08514615 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 3,998E-03 0,084365 ! adaptation of signaling pathway GO:0022401 7 5 0,000 3,998E-03 0,08359804 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 3,998E-03 0,08284491 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 3,998E-03 0,08210522 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 3,998E-03 0,08137862 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 3,998E-03 0,08066478 ! positive regulation of histone modification GO:0031058 5 5 0,000 3,998E-03 0,07996334 ! malate metabolic process GO:0006108 7 5 0,000 3,998E-03 0,079274 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 3,998E-03 0,07859645 ! behavioral response to pain GO:0048266 7 5 0,000 3,998E-03 0,07793038 ! clathrin coat assembly GO:0048268 11 5 0,000 3,998E-03 0,0772755 ! phototransduction, visible light GO:0007603 6 5 0,000 3,998E-03 0,07663154 ! regulation of dopamine uptake GO:0051584 9 5 0,000 3,998E-03 0,07599822 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 3,998E-03 0,07537528 ! mating behavior GO:0007617 6 5 0,000 3,998E-03 0,07476248 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 3,998E-03 0,07415955 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 3,998E-03 0,07356628 ! rhythmic behavior GO:0007622 12 5 0,000 3,998E-03 0,07298242 ! copulation GO:0007620 7 5 0,000 3,998E-03 0,07240775 ! glial cell fate commitment GO:0021781 12 5 0,000 3,998E-03 0,07184207 ! protein maturation by protein folding GO:0022417 12 5 0,000 3,998E-03 0,07128515 ! embryonic hemopoiesis GO:0035162 10 5 0,000 3,998E-03 0,0707368 ! regulation of potassium ion transport GO:0043266 9 5 0,000 3,998E-03 0,07019683 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 3,998E-03 0,06966503 ! apoptotic cell clearance GO:0043277 13 5 0,000 3,998E-03 0,06914124 ! lipoprotein particle clearance GO:0034381 9 5 0,000 3,998E-03 0,06862526 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 3,998E-03 0,06811692 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 3,998E-03 0,06761606 ! response to protozoan GO:0001562 9 5 0,000 3,998E-03 0,06712251 ! positive regulation of glycolysis GO:0045821 11 5 0,000 3,998E-03 0,06663612 ! lymph vessel development GO:0001945 7 5 0,000 3,998E-03 0,06615672 ! endochondral ossification GO:0001958 12 5 0,000 3,998E-03 0,06568417 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 3,998E-03 0,06521833 ! parathyroid gland development GO:0060017 8 5 0,000 3,998E-03 0,06475905 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 3,998E-03 0,06430619 ! anagen GO:0042640 6 5 0,000 3,998E-03 0,06385961 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 3,998E-03 0,0634192 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 3,998E-03 0,06298483 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 3,998E-03 0,06255636 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 3,998E-03 0,06213368 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 3,998E-03 0,06171667 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 3,998E-03 0,06130523 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 3,998E-03 0,06089923 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 3,998E-03 0,06049858 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 3,998E-03 0,06010317 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 3,998E-03 0,05971289 ! cardiac muscle fiber development GO:0048739 7 5 0,000 3,998E-03 0,05932764 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 3,998E-03 0,05894734 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 3,998E-03 0,05857188 ! neutrophil mediated immunity GO:0002446 6 5 0,000 3,998E-03 0,05820117 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 3,998E-03 0,05783512 ! ovulation GO:0030728 6 5 0,000 3,998E-03 0,05747365 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 3,998E-03 0,05711667 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 3,998E-03 0,0567641 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 3,998E-03 0,05641586 ! response to pH GO:0009268 9 5 0,000 3,998E-03 0,05607186 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 3,998E-03 0,05573203 ! proline biosynthetic process GO:0006561 6 5 0,000 3,998E-03 0,05539629 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 3,998E-03 0,05506458 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 3,998E-03 0,05473681 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 3,998E-03 0,05441293 ! polyol catabolic process GO:0046174 7 5 0,000 3,998E-03 0,05409285 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 3,998E-03 0,05377652 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 3,998E-03 0,05346386 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 3,998E-03 0,05315482 ! sister chromatid cohesion GO:0007062 9 5 0,000 3,998E-03 0,05284934 ! nerve growth factor processing GO:0032455 7 5 0,000 3,998E-03 0,05254734 ! urea metabolic process GO:0019627 6 5 0,000 3,998E-03 0,05224878 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 3,998E-03 0,05195358 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 3,998E-03 0,05166171 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 3,998E-03 0,0513731 ! neutrophil activation GO:0042119 5 5 0,000 3,998E-03 0,05108769 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 3,998E-03 0,05080544 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 3,998E-03 0,05052629 ! response to food GO:0032094 5 5 0,000 3,998E-03 0,05025019 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 3,998E-03 0,04997709 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 3,998E-03 0,04970694 ! paraxial mesoderm development GO:0048339 9 5 0,000 3,998E-03 0,0494397 ! forebrain neuron development GO:0021884 7 5 0,000 3,998E-03 0,04917532 ! melanosome organization GO:0032438 7 5 0,000 3,998E-03 0,04891375 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 3,998E-03 0,04865494 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 3,998E-03 0,04839887 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 3,998E-03 0,04814547 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 3,998E-03 0,04789471 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 3,998E-03 0,04764655 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 3,998E-03 0,04740095 ! nucleoside transport GO:0015858 6 5 0,000 3,998E-03 0,04715787 ! nucleoside salvage GO:0043174 7 5 0,000 3,998E-03 0,04691727 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 3,998E-03 0,04667911 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 3,998E-03 0,04644336 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 3,998E-03 0,04620997 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 3,998E-03 0,04597892 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 3,998E-03 0,04575017 ! early endosome to late endosome transport GO:0045022 11 5 0,000 3,998E-03 0,04552369 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 3,998E-03 0,04529943 ! depyrimidination GO:0045008 8 5 0,000 3,998E-03 0,04507737 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 3,998E-03 0,04485749 ! 5S class rRNA transcription GO:0042791 8 5 0,000 3,998E-03 0,04463973 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 3,998E-03 0,04442408 ! neuronal ion channel clustering GO:0045161 7 5 0,000 3,998E-03 0,0442105 ! sodium ion homeostasis GO:0055078 6 5 0,000 3,998E-03 0,04399897 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 3,998E-03 0,04378945 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 3,998E-03 0,04358192 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 3,998E-03 0,04337634 ! monocyte differentiation GO:0030224 8 5 0,000 3,998E-03 0,0431727 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 3,998E-03 0,04297096 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 3,998E-03 0,04277109 ! centrosome duplication GO:0051298 5 5 0,000 3,998E-03 0,04257308 ! response to UV-C GO:0010225 6 5 0,000 3,998E-03 0,04237689 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 3,998E-03 0,0421825 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 3,998E-03 0,04198988 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 3,998E-03 0,04179902 ! regulation of dendrite development GO:0050773 12 5 0,000 3,998E-03 0,04160988 ! peptidyl-arginine modification GO:0018195 7 5 0,000 3,998E-03 0,04142245 ! positive regulation of organ growth GO:0046622 6 5 0,000 3,998E-03 0,0412367 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 3,998E-03 0,04105261 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 3,998E-03 0,04087015 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 3,998E-03 0,04068931 ! regulation of dopamine secretion GO:0014059 12 5 0,000 3,998E-03 0,04051006 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 3,998E-03 0,04033239 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 3,998E-03 0,04015626 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 3,998E-03 0,03998167 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 3,998E-03 0,03980859 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 3,998E-03 0,039637 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 3,998E-03 0,03946689 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 3,998E-03 0,03929822 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 3,998E-03 0,039131 ! neural tube patterning GO:0021532 6 5 0,000 3,998E-03 0,03896519 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 3,998E-03 0,03880078 ! histone demethylation GO:0016577 9 5 0,000 3,998E-03 0,03863775 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 3,998E-03 0,03847609 ! regulation of sterol transport GO:0032371 7 5 0,000 3,998E-03 0,03831577 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 3,998E-03 0,03815678 ! enteric nervous system development GO:0048484 8 5 0,000 3,998E-03 0,03799911 ! establishment of planar polarity GO:0001736 6 5 0,000 3,998E-03 0,03784273 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 3,998E-03 0,03768764 ! muscle cell proliferation GO:0033002 8 5 0,000 3,998E-03 0,03753381 ! transcription termination GO:0006353 8 5 0,000 3,998E-03 0,03738124 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 3,998E-03 0,0372299 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 3,998E-03 0,03707978 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 3,998E-03 0,03693086 ! regulation of respiratory burst GO:0060263 8 5 0,000 3,998E-03 0,03678314 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 3,998E-03 0,03663659 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 3,998E-03 0,03649121 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 3,998E-03 0,03634697 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 3,998E-03 0,03620388 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 3,998E-03 0,0360619 ! apical protein localization GO:0045176 6 5 0,000 3,998E-03 0,03592103 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 3,998E-03 0,03578126 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 3,998E-03 0,03564258 ! galactolipid metabolic process GO:0019374 7 5 0,000 3,998E-03 0,03550496 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 3,998E-03 0,0353684 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 3,998E-03 0,03523289 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 3,998E-03 0,03509841 ! triglyceride catabolic process GO:0019433 6 5 0,000 3,998E-03 0,03496496 ! glial cell migration GO:0008347 10 5 0,000 3,998E-03 0,03483252 ! determination of adult lifespan GO:0008340 8 5 0,000 3,998E-03 0,03470107 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 3,998E-03 0,03457062 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 3,998E-03 0,03444114 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 3,998E-03 0,03431263 ! somatic stem cell maintenance GO:0035019 13 5 0,000 3,998E-03 0,03418507 ! cerebellar cortex formation GO:0021697 6 5 0,000 3,998E-03 0,03405846 ! neural plate development GO:0001840 6 5 0,000 3,998E-03 0,03393278 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 3,998E-03 0,03380803 ! regulation of sensory perception GO:0051931 6 5 0,000 3,998E-03 0,03368419 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 3,998E-03 0,03356126 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 3,998E-03 0,03343922 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 3,998E-03 0,03331806 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 3,998E-03 0,03319778 ! sensory cilium assembly GO:0035058 6 5 0,000 3,998E-03 0,03307836 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 3,998E-03 0,0329598 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 3,998E-03 0,03284209 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 3,998E-03 0,03272521 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 3,998E-03 0,03260916 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 3,998E-03 0,03249394 ! protein amino acid prenylation GO:0018346 9 5 0,000 3,998E-03 0,03237952 ! organ regeneration GO:0031100 7 5 0,000 3,998E-03 0,03226591 ! NAD biosynthetic process GO:0009435 7 5 0,000 3,998E-03 0,03215309 ! carnitine metabolic process GO:0009437 5 5 0,000 3,998E-03 0,03204106 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 3,998E-03 0,03192981 ! cellular anion homeostasis GO:0030002 6 5 0,000 3,998E-03 0,03181932 GO:0055081|anion homeostasis, ! tRNA transcription GO:0009304 11 6 0,000 4,796E-03 0,03803738 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 4,796E-03 0,03790667 GO:0045346|regulation of MHC class II biosynthetic process, ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 4,796E-03 0,03777685 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 4,796E-03 0,03764792 GO:0030816|positive regulation of cAMP metabolic process, ! regulation of helicase activity GO:0051095 11 6 0,000 4,796E-03 0,03751986 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 4,796E-03 0,03739268 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 4,796E-03 0,03726635 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 4,796E-03 0,03714087 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 4,796E-03 0,03701624 ! positive regulation of axon extension GO:0045773 8 6 0,000 4,796E-03 0,03689244 ! prostate gland development GO:0030850 9 6 0,000 4,796E-03 0,03676947 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 4,796E-03 0,03664731 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 4,796E-03 0,03652596 ! forebrain neuron differentiation GO:0021879 9 6 0,000 4,796E-03 0,03640541 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 4,796E-03 0,03628566 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 4,796E-03 0,03616669 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 4,796E-03 0,0360485 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 4,796E-03 0,03593107 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 4,796E-03 0,03581441 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 4,796E-03 0,03569851 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 4,796E-03 0,03558335 ! neuron adhesion GO:0007158 9 6 0,000 4,796E-03 0,03546894 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 4,796E-03 0,03535526 ! establishment of tissue polarity GO:0007164 7 6 0,000 4,796E-03 0,0352423 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 4,796E-03 0,03513006 ! signal peptide processing GO:0006465 8 6 0,000 4,796E-03 0,03501854 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 4,796E-03 0,03490772 ! mRNA stabilization GO:0048255 15 6 0,000 4,796E-03 0,0347976 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 4,796E-03 0,03468817 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 4,796E-03 0,03457943 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 4,796E-03 0,03447137 ! opsonization GO:0008228 8 6 0,000 4,796E-03 0,03436399 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 4,796E-03 0,03425727 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 4,796E-03 0,03415121 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 4,796E-03 0,0340458 ! protein amino acid dealkylation GO:0008214 11 6 0,000 4,796E-03 0,03394105 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 4,796E-03 0,03383693 ! photoreceptor cell development GO:0042461 10 6 0,000 4,796E-03 0,03373345 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 4,796E-03 0,03363061 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 4,796E-03 0,03352839 ! mechanosensory behavior GO:0007638 8 6 0,000 4,796E-03 0,03342679 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 4,796E-03 0,0333258 ! negative regulation of endocytosis GO:0045806 8 6 0,000 4,796E-03 0,03322542 ! response to interferon-gamma GO:0034341 12 6 0,000 4,796E-03 0,03312564 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 4,796E-03 0,03302647 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 4,796E-03 0,03292788 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 4,796E-03 0,03282988 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 4,796E-03 0,03273246 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 4,796E-03 0,03263562 ! cGMP-mediated signaling GO:0019934 10 6 0,000 4,796E-03 0,03253935 ! activation of MAPKKK activity GO:0000185 10 6 0,000 4,796E-03 0,03244365 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 4,796E-03 0,0323485 ! thymic T cell selection GO:0045061 12 6 0,000 4,796E-03 0,03225392 ! protein lipoylation GO:0009249 10 6 0,000 4,796E-03 0,03215988 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 4,796E-03 0,03206639 ! pigment granule organization GO:0048753 11 6 0,000 4,796E-03 0,03197345 ! drug transport GO:0015893 6 6 0,000 4,796E-03 0,03188104 ! cysteine metabolic process GO:0006534 7 6 0,000 4,796E-03 0,03178916 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 4,796E-03 0,03169782 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 4,796E-03 0,03160699 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 4,796E-03 0,03151668 ! histidine metabolic process GO:0006547 6 6 0,000 4,796E-03 0,03142689 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 4,796E-03 0,03133761 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 4,796E-03 0,03124884 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 4,796E-03 0,03116056 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 4,796E-03 0,03107279 ! adenohypophysis development GO:0021984 10 6 0,000 4,796E-03 0,0309855 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 4,796E-03 0,03089871 ! hyperosmotic response GO:0006972 8 6 0,000 4,796E-03 0,0308124 ! microtubule nucleation GO:0007020 10 6 0,000 4,796E-03 0,03072657 ! ER overload response GO:0006983 7 6 0,000 4,796E-03 0,03064122 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 4,796E-03 0,03055634 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 4,796E-03 0,03047193 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 4,796E-03 0,03038799 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 4,796E-03 0,0303045 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 4,796E-03 0,03022148 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 4,796E-03 0,03013891 ! response to dietary excess GO:0002021 7 6 0,000 4,796E-03 0,03005678 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 4,796E-03 0,02997511 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 4,796E-03 0,02989387 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 4,796E-03 0,02981308 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 4,796E-03 0,02973272 ! glycerol ether catabolic process GO:0044269 8 6 0,000 4,796E-03 0,02965279 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 4,796E-03 0,0295733 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 4,796E-03 0,02949422 ! neuron apoptosis GO:0051402 8 6 0,000 4,796E-03 0,02941557 ! organic alcohol transport GO:0015850 9 6 0,000 4,796E-03 0,02933734 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 4,796E-03 0,02925952 ! T cell mediated immunity GO:0002456 12 6 0,000 4,796E-03 0,02918212 ! male sex determination GO:0030238 9 6 0,000 4,796E-03 0,02910512 ! carnitine transport GO:0015879 8 6 0,000 4,796E-03 0,02902853 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 4,796E-03 0,02895234 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 4,796E-03 0,02887654 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 4,796E-03 0,02880115 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 4,796E-03 0,02872614 ! positive regulation of exocytosis GO:0045921 6 6 0,000 4,796E-03 0,02865153 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 4,796E-03 0,0285773 ! parturition GO:0007567 12 6 0,000 4,796E-03 0,02850346 ! negative regulation of translational initiation GO:0045947 7 6 0,000 4,796E-03 0,02843 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 4,796E-03 0,02835691 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 4,796E-03 0,0282842 ! spindle checkpoint GO:0031577 14 6 0,000 4,796E-03 0,02821187 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 4,796E-03 0,0281399 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 4,796E-03 0,02806829 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 4,796E-03 0,02799705 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 4,796E-03 0,02792618 ! macrophage differentiation GO:0030225 10 6 0,000 4,796E-03 0,02785566 ! astrocyte development GO:0014002 14 6 0,000 4,796E-03 0,02778549 ! hyaluronan metabolic process GO:0030212 6 6 0,000 4,796E-03 0,02771568 ! purine base biosynthetic process GO:0009113 14 6 0,000 4,796E-03 0,02764621 ! interaction with symbiont GO:0051702 8 6 0,000 4,796E-03 0,0275771 ! anterograde axon cargo transport GO:0008089 8 6 0,000 4,796E-03 0,02750833 ! skeletal muscle contraction GO:0003009 6 6 0,000 4,796E-03 0,0274399 ! eating behavior GO:0042755 6 6 0,000 4,796E-03 0,02737181 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 4,796E-03 0,02730406 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 4,796E-03 0,02723664 ! response to copper ion GO:0046688 9 6 0,000 4,796E-03 0,02716956 ! DNA topological change GO:0006265 8 6 0,000 4,796E-03 0,0271028 ! response to exogenous dsRNA GO:0043330 8 6 0,000 4,796E-03 0,02703637 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 4,796E-03 0,02697027 ! establishment of melanosome localization GO:0032401 9 6 0,000 4,796E-03 0,02690449 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 4,796E-03 0,02683903 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 4,796E-03 0,02677388 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 4,796E-03 0,02670905 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 4,796E-03 0,02664454 ! nucleoside catabolic process GO:0009164 6 6 0,000 4,796E-03 0,02658034 ! gas homeostasis GO:0033483 11 6 0,000 4,796E-03 0,02651644 ! hair follicle maturation GO:0048820 7 6 0,000 4,796E-03 0,02645285 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 4,796E-03 0,02638957 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 4,796E-03 0,02632659 ! Schwann cell development GO:0014044 14 6 0,000 4,796E-03 0,0262639 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 4,796E-03 0,02620152 ! dendrite morphogenesis GO:0048813 9 6 0,000 4,796E-03 0,02613943 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 4,796E-03 0,02607764 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 4,796E-03 0,02601613 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 4,796E-03 0,02595492 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 4,796E-03 0,02589399 ! histone ubiquitination GO:0016574 7 6 0,000 4,796E-03 0,02583335 ! regulation of meiosis GO:0040020 10 6 0,000 4,796E-03 0,02577299 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 4,796E-03 0,02571291 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 4,796E-03 0,02565312 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 4,796E-03 0,0255936 ! regulation of mast cell activation GO:0033003 6 6 0,000 4,796E-03 0,02553435 ! membrane to membrane docking GO:0022614 12 6 0,000 4,796E-03 0,02547538 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 4,796E-03 0,02541668 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 4,796E-03 0,02535825 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 4,796E-03 0,02530009 ! receptor internalization GO:0031623 9 6 0,000 4,796E-03 0,0252422 ! neutrophil homeostasis GO:0001780 6 6 0,000 4,796E-03 0,02518457 ! coenzyme A metabolic process GO:0015936 9 6 0,000 4,796E-03 0,0251272 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 4,796E-03 0,02507009 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 4,796E-03 0,02501324 ! protein deubiquitination GO:0016579 8 6 0,000 4,796E-03 0,02495665 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 4,796E-03 0,02490032 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 4,796E-03 0,02484423 ! peptidyl-histidine modification GO:0018202 9 6 0,000 4,796E-03 0,0247884 ! axonal fasciculation GO:0007413 9 6 0,000 4,796E-03 0,02473282 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 4,796E-03 0,02467749 ! thiamin metabolic process GO:0006772 6 6 0,000 4,796E-03 0,02462241 ! midbrain development GO:0030901 6 6 0,000 4,796E-03 0,02456757 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 4,796E-03 0,02451298 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 4,796E-03 0,02445862 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 4,796E-03 0,02440451 ! progesterone metabolic process GO:0042448 8 6 0,000 4,796E-03 0,02435064 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 4,796E-03 0,024297 ! glycolipid catabolic process GO:0019377 13 6 0,000 4,796E-03 0,0242436 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 4,796E-03 0,02419044 ! positive regulation of glucose import GO:0046326 6 6 0,000 4,796E-03 0,0241375 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 4,796E-03 0,0240848 ! adult feeding behavior GO:0008343 6 6 0,000 4,796E-03 0,02403233 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 4,796E-03 0,02398009 ! blastocyst growth GO:0001832 15 6 0,000 4,796E-03 0,02392807 ! pigment granule transport GO:0051904 12 6 0,000 4,796E-03 0,02387628 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 4,796E-03 0,02382471 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 4,796E-03 0,02377336 ! catecholamine transport GO:0051937 7 6 0,000 4,796E-03 0,02372224 ! organ or tissue specific immune response GO:0002251 7 6 0,000 4,796E-03 0,02367133 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 4,796E-03 0,02362064 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 4,796E-03 0,02357017 ! negative regulation of B cell activation GO:0050869 9 6 0,000 4,796E-03 0,02351991 ! protein prenylation GO:0018342 10 6 0,000 4,796E-03 0,02346987 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 4,796E-03 0,02342004 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 4,796E-03 0,02337042 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 4,796E-03 0,02332101 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 4,796E-03 0,02327181 ! positive regulation of coagulation GO:0050820 11 6 0,000 4,796E-03 0,02322282 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 5,593E-03 0,02702632 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 5,593E-03 0,02696966 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 5,593E-03 0,02691324 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 5,593E-03 0,02685706 ! synaptonemal complex assembly GO:0007130 10 7 0,000 5,593E-03 0,0268011 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 5,593E-03 0,02674538 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 5,593E-03 0,0266899 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 5,593E-03 0,02663464 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 5,593E-03 0,02657961 ! reproductive behavior GO:0019098 12 7 0,000 5,593E-03 0,0265248 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 5,593E-03 0,02647023 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 5,593E-03 0,02641587 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 5,593E-03 0,02636174 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 5,593E-03 0,02630783 ! oligopeptide transport GO:0006857 11 7 0,000 5,593E-03 0,02625414 ! protein amino acid sulfation GO:0006477 9 7 0,000 5,593E-03 0,02620067 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 5,593E-03 0,02614742 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 5,593E-03 0,02609438 ! RNA methylation GO:0001510 11 7 0,000 5,593E-03 0,02604156 ! pericardium development GO:0060039 8 7 0,000 5,593E-03 0,02598895 ! macrophage chemotaxis GO:0048246 10 7 0,000 5,593E-03 0,02593655 ! fibril organization GO:0043206 13 7 0,000 5,593E-03 0,02588437 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 5,593E-03 0,02583239 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 5,593E-03 0,02578062 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 5,593E-03 0,02572906 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 5,593E-03 0,0256777 ! lipoprotein transport GO:0042953 9 7 0,000 5,593E-03 0,02562655 ! cerebral cortex cell migration GO:0021795 11 7 0,000 5,593E-03 0,02557561 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 5,593E-03 0,02552486 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 5,593E-03 0,02547432 ! estrogen metabolic process GO:0008210 14 7 0,000 5,593E-03 0,02542397 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 5,593E-03 0,02537383 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 5,593E-03 0,02532388 ! chemosensory behavior GO:0007635 9 7 0,000 5,593E-03 0,02527413 ! microtubule bundle formation GO:0001578 8 7 0,000 5,593E-03 0,02522457 ! T-helper 1 type immune response GO:0042088 11 7 0,000 5,593E-03 0,0251752 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 5,593E-03 0,02512603 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 5,593E-03 0,02507706 ! leukocyte degranulation GO:0043299 10 7 0,000 5,593E-03 0,02502827 ! bile acid and bile salt transport GO:0015721 9 7 0,000 5,593E-03 0,02497967 ! reflex GO:0060004 12 7 0,000 5,593E-03 0,02493126 ! positive regulation of isotype switching GO:0045830 15 7 0,000 5,593E-03 0,02488304 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 5,593E-03 0,024835 ! protein-cofactor linkage GO:0018065 13 7 0,000 5,593E-03 0,02478715 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 5,593E-03 0,02473948 ! glycerolipid catabolic process GO:0046503 9 7 0,000 5,593E-03 0,024692 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 5,593E-03 0,02464469 ! spinal cord patterning GO:0021511 7 7 0,000 5,593E-03 0,02459757 ! hemoglobin metabolic process GO:0020027 10 7 0,000 5,593E-03 0,02455063 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 5,593E-03 0,02450387 ! adrenal gland development GO:0030325 17 7 0,000 5,593E-03 0,02445728 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 5,593E-03 0,02441087 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 5,593E-03 0,02436464 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 5,593E-03 0,02431858 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 5,593E-03 0,0242727 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 5,593E-03 0,02422699 ! endosome organization GO:0007032 10 7 0,000 5,593E-03 0,02418145 ! thyroid hormone generation GO:0006590 11 7 0,000 5,593E-03 0,02413608 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 5,593E-03 0,02409088 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 5,593E-03 0,02404585 ! regulation of pigmentation during development GO:0048070 15 7 0,000 5,593E-03 0,02400099 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 5,593E-03 0,02395629 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 5,593E-03 0,02391177 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 5,593E-03 0,0238674 ! galactose metabolic process GO:0006012 10 7 0,000 5,593E-03 0,0238232 ! vesicle fusion GO:0006906 15 7 0,000 5,593E-03 0,02377917 ! intracellular pH reduction GO:0051452 10 7 0,000 5,593E-03 0,02373529 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 5,593E-03 0,02369158 ! organ growth GO:0035265 11 7 0,000 5,593E-03 0,02364803 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 5,593E-03 0,02360464 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 5,593E-03 0,02356141 ! Rac protein signal transduction GO:0016601 7 7 0,000 5,593E-03 0,02351834 ! retinol metabolic process GO:0042572 9 7 0,000 5,593E-03 0,02347542 ! behavioral fear response GO:0001662 13 7 0,000 5,593E-03 0,02343266 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 5,593E-03 0,02339005 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 5,593E-03 0,0233476 ! rRNA modification GO:0000154 12 7 0,000 5,593E-03 0,02330531 ! protein heterooligomerization GO:0051291 10 7 0,000 5,593E-03 0,02326316 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 5,593E-03 0,02322117 ! response to UV-B GO:0010224 11 7 0,000 5,593E-03 0,02317933 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 5,593E-03 0,02313764 ! protein retention in ER lumen GO:0006621 12 7 0,000 5,593E-03 0,0230961 ! intermediate filament organization GO:0045109 11 7 0,000 5,593E-03 0,02305471 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 5,593E-03 0,02301347 ! cardiac muscle cell development GO:0055013 9 7 0,000 5,593E-03 0,02297237 ! fibrinolysis GO:0042730 9 7 0,000 5,593E-03 0,02293143 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 5,593E-03 0,02289062 ! regulation of circadian rhythm GO:0042752 11 7 0,000 5,593E-03 0,02284996 ! B cell lineage commitment GO:0002326 17 7 0,000 5,593E-03 0,02280945 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 5,593E-03 0,02276908 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 5,593E-03 0,02272885 ! response to tropane GO:0014073 13 7 0,000 5,593E-03 0,02268876 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 5,593E-03 0,02264882 ! melanosome localization GO:0032400 10 7 0,000 5,593E-03 0,02260902 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 5,593E-03 0,02256935 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 5,593E-03 0,02252982 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 5,593E-03 0,02249044 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 5,593E-03 0,02245119 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 5,593E-03 0,02241207 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 5,593E-03 0,0223731 ! mast cell activation GO:0045576 9 7 0,000 5,593E-03 0,02233425 ! multicellular organismal aging GO:0010259 11 7 0,000 5,593E-03 0,02229555 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 5,593E-03 0,02225697 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 5,593E-03 0,02221853 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 5,593E-03 0,02218022 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 5,593E-03 0,02214205 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 5,593E-03 0,022104 ! establishment of nucleus localization GO:0040023 13 7 0,000 5,593E-03 0,02206609 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 5,593E-03 0,0220283 ! T cell lineage commitment GO:0002360 12 7 0,000 5,593E-03 0,02199065 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 5,593E-03 0,02195312 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 5,593E-03 0,02191572 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 5,593E-03 0,02187845 ! regulation of lipid transport GO:0032368 13 7 0,000 5,593E-03 0,02184131 ! response to tumor cell GO:0002347 12 7 0,000 5,593E-03 0,02180429 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 5,593E-03 0,02176739 ! neuroblast proliferation GO:0007405 13 7 0,000 5,593E-03 0,02173062 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 5,593E-03 0,02169398 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 5,593E-03 0,02165746 ! peptidyl-threonine modification GO:0018210 18 7 0,000 5,593E-03 0,02162106 ! diuresis GO:0030146 12 7 0,000 5,593E-03 0,02158478 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 5,593E-03 0,02154863 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 5,593E-03 0,02151259 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 5,593E-03 0,02147668 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 5,593E-03 0,02144088 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 5,593E-03 0,02140521 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 5,593E-03 0,02136965 ! melanin biosynthetic process GO:0042438 8 7 0,000 5,593E-03 0,02133421 ! regulation of synaptogenesis GO:0051963 10 7 0,000 5,593E-03 0,02129889 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 5,593E-03 0,02126369 ! dopamine biosynthetic process GO:0042416 15 7 0,000 5,593E-03 0,0212286 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 5,593E-03 0,02119362 ! lymph node development GO:0048535 9 7 0,000 5,593E-03 0,02115877 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 5,593E-03 0,02112402 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 5,593E-03 0,02108939 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 5,593E-03 0,02105488 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 5,593E-03 0,02102047 ! endosome to lysosome transport GO:0008333 10 7 0,000 5,593E-03 0,02098618 ! ATP catabolic process GO:0006200 10 7 0,000 5,593E-03 0,020952 ! establishment of pigment granule localization GO:0051905 13 7 0,000 5,593E-03 0,02091793 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 5,593E-03 0,02088398 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 5,593E-03 0,02085013 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 5,593E-03 0,02081639 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 5,593E-03 0,02078276 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 5,593E-03 0,02074924 ! muscle adaptation GO:0043500 12 7 0,000 5,593E-03 0,02071583 ! amino sugar catabolic process GO:0046348 9 7 0,000 5,593E-03 0,02068252 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 5,593E-03 0,02064933 ! retina homeostasis GO:0001895 9 7 0,000 5,593E-03 0,02061623 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 5,593E-03 0,02058325 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 5,593E-03 0,02055037 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 5,593E-03 0,02051759 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 5,593E-03 0,02048492 ! behavioral response to nicotine GO:0035095 11 7 0,000 5,593E-03 0,02045235 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 5,593E-03 0,02041989 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 5,593E-03 0,02038753 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 6,39E-03 0,02325452 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 6,39E-03 0,02321778 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 6,39E-03 0,02318116 ! axon extension GO:0048675 11 8 0,000 6,39E-03 0,02314465 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 6,39E-03 0,02310826 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 6,39E-03 0,02307199 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 6,39E-03 0,02303582 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 6,39E-03 0,02299977 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 6,39E-03 0,02296384 ! cell proliferation in forebrain GO:0021846 10 8 0,000 6,39E-03 0,02292801 ! positive regulation of B cell proliferation GO:0030890 11 8 0,000 6,39E-03 0,0228923 ! phosphate transport GO:0006817 10 8 0,000 6,39E-03 0,0228567 ! N-glycan processing GO:0006491 12 8 0,000 6,39E-03 0,0228212 ! Golgi to endosome transport GO:0006895 16 8 0,000 6,39E-03 0,02278582 ! UTP metabolic process GO:0046051 8 8 0,000 6,39E-03 0,02275055 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 6,39E-03 0,02271539 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 6,39E-03 0,02268033 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 6,39E-03 0,02264539 ! neurotransmitter uptake GO:0001504 10 8 0,000 6,39E-03 0,02261055 ! succinate metabolic process GO:0006105 14 8 0,000 6,39E-03 0,02257582 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 6,39E-03 0,02254119 ! smoothened signaling pathway GO:0007224 8 8 0,000 6,39E-03 0,02250667 ! membrane hyperpolarization GO:0060081 10 8 0,000 6,39E-03 0,02247226 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 6,39E-03 0,02243795 ! keratinocyte proliferation GO:0043616 12 8 0,000 6,39E-03 0,02240374 ! middle ear morphogenesis GO:0042474 9 8 0,000 6,39E-03 0,02236964 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 6,39E-03 0,02233565 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 6,39E-03 0,02230175 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 6,39E-03 0,02226796 ! ganglioside metabolic process GO:0001573 15 8 0,000 6,39E-03 0,02223427 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 6,39E-03 0,02220069 ! pseudouridine synthesis GO:0001522 9 8 0,000 6,39E-03 0,0221672 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 6,39E-03 0,02213382 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 6,39E-03 0,02210053 ! endothelial cell differentiation GO:0045446 14 8 0,000 6,39E-03 0,02206735 ! ceramide biosynthetic process GO:0046513 9 8 0,000 6,39E-03 0,02203427 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 6,39E-03 0,02200128 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 0,000 6,39E-03 0,02196839 ! astrocyte differentiation GO:0048708 16 8 0,000 6,39E-03 0,02193561 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 6,39E-03 0,02190291 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 6,39E-03 0,02187032 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 6,39E-03 0,02183782 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 6,39E-03 0,02180542 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 6,39E-03 0,02177312 ! melanin metabolic process GO:0006582 12 8 0,000 6,39E-03 0,02174091 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 6,39E-03 0,0217088 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 6,39E-03 0,02167678 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 6,39E-03 0,02164485 ! macrophage activation GO:0042116 12 8 0,000 6,39E-03 0,02161302 ! regulation of type I interferon production GO:0032479 8 8 0,000 6,39E-03 0,02158129 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 6,39E-03 0,02154964 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 6,39E-03 0,02151809 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 6,39E-03 0,02148663 ! regulation of vascular permeability GO:0043114 12 8 0,000 6,39E-03 0,02145526 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 6,39E-03 0,02142399 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 6,39E-03 0,0213928 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 6,39E-03 0,02136171 ! ruffle organization GO:0031529 11 8 0,000 6,39E-03 0,0213307 ! osteoblast development GO:0002076 13 8 0,000 6,39E-03 0,02129979 ! lens development in camera-type eye GO:0002088 10 8 0,000 6,39E-03 0,02126897 ! positive regulation of vasodilation GO:0045909 12 8 0,000 6,39E-03 0,02123823 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 6,39E-03 0,02120758 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 6,39E-03 0,02117703 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 6,39E-03 0,02114656 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 6,39E-03 0,02111617 ! Schwann cell differentiation GO:0014037 17 8 0,000 6,39E-03 0,02108588 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 6,39E-03 0,02105567 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 6,39E-03 0,02102554 ! regulation of gliogenesis GO:0014013 20 8 0,000 6,39E-03 0,02099551 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 6,39E-03 0,02096556 ! oligodendrocyte development GO:0014003 8 8 0,000 6,39E-03 0,02093569 ! segment specification GO:0007379 10 8 0,000 6,39E-03 0,02090591 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 6,39E-03 0,02087622 ! cellular extravasation GO:0045123 11 8 0,000 6,39E-03 0,0208466 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 6,39E-03 0,02081708 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 6,39E-03 0,02078763 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 6,39E-03 0,02075827 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 6,39E-03 0,02072899 ! snRNA metabolic process GO:0016073 10 8 0,000 6,39E-03 0,0206998 GO:0016180|snRNA processing, ! phosphoinositide 3-kinase cascade GO:0014065 23 8 0,000 6,39E-03 0,02067068 ! regulation of interleukin-4 production GO:0032673 16 8 0,000 6,39E-03 0,02064165 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 6,39E-03 0,0206127 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 6,39E-03 0,02058383 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 6,39E-03 0,02055504 ! nucleosome disassembly GO:0006337 12 8 0,000 6,39E-03 0,02052633 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 6,39E-03 0,02049771 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 6,39E-03 0,02046916 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 6,39E-03 0,02044069 ! icosanoid secretion GO:0032309 12 8 0,000 6,39E-03 0,0204123 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 6,39E-03 0,02038399 ! leukocyte activation during immune response GO:0002366 13 8 0,000 6,39E-03 0,02035576 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 6,39E-03 0,0203276 ! cerebellum morphogenesis GO:0021587 9 8 0,000 6,39E-03 0,02029952 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 6,39E-03 0,02027153 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 6,39E-03 0,0202436 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 6,39E-03 0,02021576 ! sterol catabolic process GO:0016127 9 8 0,000 6,39E-03 0,02018799 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 6,39E-03 0,0201603 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 6,39E-03 0,02013268 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 6,39E-03 0,02010514 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 6,39E-03 0,02007767 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 6,39E-03 0,02005028 ! prophase GO:0051324 11 8 0,000 6,39E-03 0,02002296 ! S phase GO:0051320 8 8 0,000 6,39E-03 0,01999572 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 6,39E-03 0,01996855 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 6,39E-03 0,01994146 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 6,39E-03 0,01991444 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 6,39E-03 0,01988749 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 6,39E-03 0,01986062 ! hormone catabolic process GO:0042447 13 8 0,000 6,39E-03 0,01983381 ! quaternary ammonium group transport GO:0015697 10 8 0,000 6,39E-03 0,01980708 ! myeloid cell homeostasis GO:0002262 8 8 0,000 6,39E-03 0,01978042 ! regulation of fibrinolysis GO:0051917 13 8 0,000 6,39E-03 0,01975384 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 6,39E-03 0,01972732 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 6,39E-03 0,01970088 ! regulation of telomere maintenance GO:0032204 10 8 0,000 6,39E-03 0,01967451 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 6,39E-03 0,0196482 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 6,39E-03 0,01962197 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 6,39E-03 0,01959581 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 6,39E-03 0,01956971 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 6,39E-03 0,01954369 ! lamellipodium assembly GO:0030032 9 8 0,000 6,39E-03 0,01951774 ! regulation of embryonic development GO:0045995 16 8 0,000 6,39E-03 0,01949185 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 6,39E-03 0,01946603 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 6,39E-03 0,01944029 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 6,39E-03 0,0194146 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 7,186E-03 0,02180451 ! regulation of developmental growth GO:0048638 13 9 0,000 7,186E-03 0,02177578 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 7,186E-03 0,02174713 ! telencephalon cell migration GO:0022029 16 9 0,000 7,186E-03 0,02171855 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 7,186E-03 0,02169005 ! pentose-phosphate shunt GO:0006098 12 9 0,000 7,186E-03 0,02166162 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 7,186E-03 0,02163327 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 7,186E-03 0,02160499 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 7,186E-03 0,02157679 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 7,186E-03 0,02154866 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 7,186E-03 0,0215206 ! GTP metabolic process GO:0046039 9 9 0,000 7,186E-03 0,02149261 ! elastic fiber assembly GO:0048251 13 9 0,000 7,186E-03 0,0214647 ! social behavior GO:0035176 14 9 0,000 7,186E-03 0,02143686 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 7,186E-03 0,02140909 ! artery development GO:0060840 19 9 0,000 7,186E-03 0,0213814 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 7,186E-03 0,02135377 ! regulation of glycolysis GO:0006110 15 9 0,000 7,186E-03 0,02132622 ! response to pain GO:0048265 16 9 0,000 7,186E-03 0,02129874 ! protein complex disassembly GO:0043241 17 9 0,000 7,186E-03 0,02127132 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 7,186E-03 0,02124398 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 7,186E-03 0,02121671 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 7,186E-03 0,02118951 ! lung alveolus development GO:0048286 17 9 0,000 7,186E-03 0,02116238 ! ciliary or flagellar motility GO:0001539 10 9 0,000 7,186E-03 0,02113532 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 7,186E-03 0,02110833 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 7,186E-03 0,0210814 ! regulation of exit from mitosis GO:0007096 12 9 0,000 7,186E-03 0,02105455 ! ventral spinal cord development GO:0021517 11 9 0,000 7,186E-03 0,02102776 ! protein targeting to ER GO:0045047 19 9 0,000 7,186E-03 0,02100104 ! T cell selection GO:0045058 18 9 0,000 7,186E-03 0,02097439 ! endoderm development GO:0007492 12 9 0,000 7,186E-03 0,02094781 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 7,186E-03 0,02092129 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 7,186E-03 0,02089484 ! arginine catabolic process GO:0006527 10 9 0,000 7,186E-03 0,02086846 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 7,186E-03 0,02084214 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 7,186E-03 0,02081589 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 7,186E-03 0,02078971 ! phosphagen metabolic process GO:0006599 12 9 0,000 7,186E-03 0,02076359 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 7,186E-03 0,02073754 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 7,186E-03 0,02071155 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 7,186E-03 0,02068563 ! regulation of stress fiber formation GO:0051492 20 9 0,000 7,186E-03 0,02065977 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 7,186E-03 0,02063398 ! mannose metabolic process GO:0006013 9 9 0,000 7,186E-03 0,02060825 ! substrate-bound cell migration GO:0006929 10 9 0,000 7,186E-03 0,02058259 ! receptor clustering GO:0043113 15 9 0,000 7,186E-03 0,02055699 ! epithelial cell development GO:0002064 10 9 0,000 7,186E-03 0,02053145 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 7,186E-03 0,02050598 ! retinoic acid metabolic process GO:0042573 11 9 0,000 7,186E-03 0,02048057 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 7,186E-03 0,02045522 ! positive regulation of translational initiation GO:0045948 10 9 0,000 7,186E-03 0,02042994 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 7,186E-03 0,02040471 ! motor axon guidance GO:0008045 14 9 0,000 7,186E-03 0,02037955 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 7,186E-03 0,02035446 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 7,186E-03 0,02032942 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 7,186E-03 0,02030445 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 7,186E-03 0,02027953 ! blastoderm segmentation GO:0007350 11 9 0,000 7,186E-03 0,02025468 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 7,186E-03 0,02022989 ! DNA ligation GO:0006266 14 9 0,000 7,186E-03 0,02020516 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 7,186E-03 0,02018049 ! response to amine stimulus GO:0014075 13 9 0,000 7,186E-03 0,02015588 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 7,186E-03 0,02013133 ! erythrocyte development GO:0048821 11 9 0,000 7,186E-03 0,02010684 ! renal water homeostasis GO:0003091 14 9 0,000 7,186E-03 0,0200824 ! mRNA cleavage GO:0006379 13 9 0,000 7,186E-03 0,02005803 ! hindbrain morphogenesis GO:0021575 12 9 0,000 7,186E-03 0,02003372 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 7,186E-03 0,02000947 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 7,186E-03 0,01998527 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 7,186E-03 0,01996113 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 7,186E-03 0,01993705 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 7,186E-03 0,01991303 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 7,186E-03 0,01988907 ! acid secretion GO:0046717 14 9 0,000 7,186E-03 0,01986517 ! musculoskeletal movement GO:0050881 11 9 0,000 7,186E-03 0,01984132 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 7,186E-03 0,01981753 ! methionine biosynthetic process GO:0009086 10 9 0,000 7,186E-03 0,01979379 ! purine base metabolic process GO:0006144 18 9 0,000 7,186E-03 0,01977012 ! oocyte differentiation GO:0009994 12 9 0,000 7,186E-03 0,0197465 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 7,186E-03 0,01972293 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 7,186E-03 0,01969943 ! spleen development GO:0048536 15 9 0,000 7,186E-03 0,01967597 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 7,186E-03 0,01965258 ! anterior/posterior axis specification GO:0009948 11 9 0,000 7,186E-03 0,01962924 ! regulation of RNA splicing GO:0043484 14 9 0,000 7,186E-03 0,01960595 ! detection of calcium ion GO:0005513 13 9 0,000 7,186E-03 0,01958272 ! blastocyst formation GO:0001825 12 9 0,000 7,186E-03 0,01955955 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 7,186E-03 0,01953643 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 7,186E-03 0,01951336 ! regulation of muscle adaptation GO:0043502 12 9 0,000 7,186E-03 0,01949035 ! regulation of amino acid transport GO:0051955 11 9 0,000 7,186E-03 0,0194674 ! positive regulation of amine transport GO:0051954 15 9 0,000 7,186E-03 0,01944449 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 7,186E-03 0,01942164 ! prepulse inhibition GO:0060134 14 9 0,000 7,186E-03 0,01939885 ! embryonic placenta development GO:0001892 12 9 0,000 7,186E-03 0,01937611 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 7,186E-03 0,01935342 ! insulin secretion GO:0030073 17 9 0,000 7,186E-03 0,01933078 ! sequestering of metal ion GO:0051238 11 9 0,000 7,186E-03 0,0193082 ! response to nicotine GO:0035094 16 9 0,000 7,186E-03 0,01928567 ! establishment of cell polarity GO:0030010 12 9 0,000 7,186E-03 0,01926319 ! nucleus localization GO:0051647 15 9 0,000 7,186E-03 0,01924077 ! regulation of synapse organization GO:0050807 12 9 0,000 7,186E-03 0,01921839 ! localization within membrane GO:0051668 15 9 0,000 7,186E-03 0,01919607 ! negative regulation of muscle development GO:0048635 12 10 0,000 7,981E-03 0,02129631 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 7,981E-03 0,02127163 ! neuron fate specification GO:0048665 11 10 0,000 7,981E-03 0,02124701 ! negative regulation of blood pressure GO:0045776 22 10 0,000 7,981E-03 0,02122245 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 7,981E-03 0,02119794 ! thyroid gland development GO:0030878 19 10 0,000 7,981E-03 0,02117349 ! regulation of B cell proliferation GO:0030888 15 10 0,000 7,981E-03 0,0211491 ! regulation of phosphatase activity GO:0010921 21 10 0,000 7,981E-03 0,02112476 ! synapsis GO:0007129 13 10 0,000 7,981E-03 0,02110048 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 7,981E-03 0,02107626 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 7,981E-03 0,02105209 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 7,981E-03 0,02102797 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 7,981E-03 0,02100391 ! sulfate transport GO:0008272 12 10 0,000 7,981E-03 0,02097991 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 7,981E-03 0,02095596 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 7,981E-03 0,02093206 ! androgen metabolic process GO:0008209 13 10 0,000 7,981E-03 0,02090822 ! phospholipid efflux GO:0033700 16 10 0,000 7,981E-03 0,02088444 ! hippocampus development GO:0021766 19 10 0,000 7,981E-03 0,0208607 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 7,981E-03 0,02083703 ! blood vessel remodeling GO:0001974 21 10 0,000 7,981E-03 0,0208134 ! positive regulation of heart contraction GO:0045823 14 10 0,000 7,981E-03 0,02078983 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 7,981E-03 0,02076631 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 7,981E-03 0,02074285 GO:0010812|negative regulation of cell-substrate adhesion, ! pathogenesis GO:0009405 13 10 0,000 7,981E-03 0,02071943 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 7,981E-03 0,02069608 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 7,981E-03 0,02067277 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 7,981E-03 0,02064952 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 7,981E-03 0,02062631 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 7,981E-03 0,02060316 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 7,981E-03 0,02058007 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 7,981E-03 0,02055702 ! melanocyte differentiation GO:0030318 15 10 0,000 7,981E-03 0,02053403 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 7,981E-03 0,02051108 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 7,981E-03 0,02048819 ! reverse cholesterol transport GO:0043691 16 10 0,000 7,981E-03 0,02046535 ! response to X-ray GO:0010165 16 10 0,000 7,981E-03 0,02044256 ! B cell proliferation GO:0042100 14 10 0,000 7,981E-03 0,02041982 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 7,981E-03 0,02039713 ! regulation of sodium ion transport GO:0002028 15 10 0,000 7,981E-03 0,02037449 ! forebrain cell migration GO:0021885 17 10 0,000 7,981E-03 0,02035191 ! lipid digestion GO:0044241 15 10 0,000 7,981E-03 0,02032937 ! phagocytosis, engulfment GO:0006911 20 10 0,000 7,981E-03 0,02030688 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 7,981E-03 0,02028444 ! UV protection GO:0009650 14 10 0,000 7,981E-03 0,02026205 ! entry into host cell GO:0030260 20 10 0,000 7,981E-03 0,02023971 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 7,981E-03 0,02021742 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 7,981E-03 0,02019518 ! negative regulation of ossification GO:0030279 19 10 0,000 7,981E-03 0,02017299 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 7,981E-03 0,02015084 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 7,981E-03 0,02012875 ! regulation of bone resorption GO:0045124 24 10 0,000 7,981E-03 0,0201067 ! alpha-beta T cell activation GO:0046631 16 10 0,000 7,981E-03 0,0200847 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 7,981E-03 0,02006275 ! regulation of organ growth GO:0046620 11 10 0,000 7,981E-03 0,02004085 ! response to dsRNA GO:0043331 18 10 0,000 7,981E-03 0,020019 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 7,981E-03 0,01999719 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 7,981E-03 0,01997543 ! embryonic axis specification GO:0000578 12 10 0,000 7,981E-03 0,01995372 ! regulation of B cell differentiation GO:0045577 16 10 0,000 7,981E-03 0,01993205 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 7,981E-03 0,01991043 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 7,981E-03 0,01988886 ! cranial nerve development GO:0021545 12 10 0,000 7,981E-03 0,01986734 ! fucose catabolic process GO:0019317 16 10 0,000 7,981E-03 0,01984586 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 7,981E-03 0,01982443 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 7,981E-03 0,01980304 ! protein sumoylation GO:0016925 12 10 0,000 7,981E-03 0,0197817 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 7,981E-03 0,01976041 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 7,981E-03 0,01973916 ! zymogen activation GO:0031638 14 10 0,000 7,981E-03 0,01971796 ! salivary gland development GO:0007431 22 10 0,000 7,981E-03 0,0196968 ! negative regulation of neurological system process GO:0031645 19 10 0,000 7,981E-03 0,01967569 ! glutathione biosynthetic process GO:0006750 11 10 0,000 7,981E-03 0,01965462 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 7,981E-03 0,0196336 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 7,981E-03 0,01961263 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 7,981E-03 0,0195917 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 7,981E-03 0,01957081 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 7,981E-03 0,01954997 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 7,981E-03 0,01952917 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 7,981E-03 0,01950842 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 7,981E-03 0,01948771 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 7,981E-03 0,01946704 ! detection of bacterium GO:0016045 10 10 0,000 7,981E-03 0,01944642 ! embryonic gut development GO:0048566 11 10 0,000 7,981E-03 0,01942584 ! activation of innate immune response GO:0002218 10 10 0,000 7,981E-03 0,01940531 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 7,981E-03 0,01938481 ! cardiac cell differentiation GO:0035051 16 10 0,000 7,981E-03 0,01936437 ! developmental induction GO:0031128 13 10 0,000 7,981E-03 0,01934396 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 7,981E-03 0,0193236 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 7,981E-03 0,01930328 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 7,981E-03 0,019283 ! negative regulation of immune effector process GO:0002698 16 10 0,000 7,981E-03 0,01926277 ! rRNA transcription GO:0009303 17 11 0,000 8,776E-03 0,02115897 ! respiratory burst GO:0045730 14 11 0,000 8,776E-03 0,02113682 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 8,776E-03 0,02111471 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 8,776E-03 0,02109264 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 8,776E-03 0,02107062 ! virus-host interaction GO:0019048 17 11 0,000 8,776E-03 0,02104865 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 8,776E-03 0,02102673 ! filopodium assembly GO:0046847 19 11 0,000 8,776E-03 0,02100485 ! Golgi vesicle budding GO:0048194 17 11 0,000 8,776E-03 0,02098301 ! RNA polyadenylation GO:0043631 19 11 0,000 8,776E-03 0,02096122 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 8,776E-03 0,02093948 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 8,776E-03 0,02091778 ! mating GO:0007618 14 11 0,000 8,776E-03 0,02089613 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 8,776E-03 0,02087452 ! T cell proliferation GO:0042098 20 11 0,000 8,776E-03 0,02085295 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 8,776E-03 0,02083143 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 8,776E-03 0,02080996 ! bone resorption GO:0045453 16 11 0,000 8,776E-03 0,02078853 ! regulated secretory pathway GO:0045055 14 11 0,000 8,776E-03 0,02076714 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 8,776E-03 0,02074579 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 8,776E-03 0,0207245 ! regulation of mRNA processing GO:0050684 18 11 0,000 8,776E-03 0,02070324 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 8,776E-03 0,02068203 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 8,776E-03 0,02066086 ! syncytium formation GO:0006949 15 11 0,000 8,776E-03 0,02063973 ! plasma membrane organization GO:0007009 18 11 0,000 8,776E-03 0,02061865 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 8,776E-03 0,02059761 ! focal adhesion formation GO:0048041 24 11 0,000 8,776E-03 0,02057661 ! mitotic spindle organization GO:0007052 15 11 0,000 8,776E-03 0,02055566 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 8,776E-03 0,02053475 ! regulation of intracellular pH GO:0051453 17 11 0,000 8,776E-03 0,02051388 ! membrane protein proteolysis GO:0033619 18 11 0,000 8,776E-03 0,02049305 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 8,776E-03 0,02047227 ! adult heart development GO:0007512 11 11 0,000 8,776E-03 0,02045153 ! chondrocyte differentiation GO:0002062 17 11 0,000 8,776E-03 0,02043083 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 8,776E-03 0,02041017 ! temperature homeostasis GO:0001659 16 11 0,000 8,776E-03 0,02038955 ! L-glutamate transport GO:0015813 16 11 0,000 8,776E-03 0,02036898 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 8,776E-03 0,02034845 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 8,776E-03 0,02032795 ! protein targeting to peroxisome GO:0006625 20 11 0,000 8,776E-03 0,0203075 ! stem cell development GO:0048864 29 11 0,000 8,776E-03 0,02028709 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 8,776E-03 0,02026673 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 8,776E-03 0,0202464 ! regulation of phagocytosis GO:0050764 14 11 0,000 8,776E-03 0,02022611 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 8,776E-03 0,02020586 ! vasoconstriction GO:0042310 15 11 0,000 8,776E-03 0,02018566 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 8,776E-03 0,02016549 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 8,776E-03 0,02014537 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 8,776E-03 0,02012528 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 8,776E-03 0,02010524 ! ribosome assembly GO:0042255 13 11 0,000 8,776E-03 0,02008523 ! nitric oxide metabolic process GO:0046209 14 11 0,000 8,776E-03 0,02006527 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 8,776E-03 0,02004534 ! chromatin silencing GO:0006342 19 11 0,000 8,776E-03 0,02002545 ! nucleosome positioning GO:0016584 13 11 0,000 8,776E-03 0,02000561 ! T cell homeostasis GO:0043029 20 11 0,000 8,776E-03 0,0199858 ! regulation of isotype switching GO:0045191 19 11 0,000 8,776E-03 0,01996603 ! regulation of leukocyte migration GO:0002685 24 11 0,000 8,776E-03 0,0199463 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 8,776E-03 0,01992661 ! protein-chromophore linkage GO:0018298 13 11 0,000 8,776E-03 0,01990696 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 8,776E-03 0,01988735 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 8,776E-03 0,01986777 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 8,776E-03 0,01984824 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 8,776E-03 0,01982874 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 8,776E-03 0,01980928 ! male genitalia development GO:0030539 13 11 0,000 8,776E-03 0,01978986 ! cholesterol efflux GO:0033344 19 11 0,000 8,776E-03 0,01977048 ! digestive tract morphogenesis GO:0048546 15 11 0,000 8,776E-03 0,01975113 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 8,776E-03 0,01973183 ! negative regulation of glucose import GO:0046325 14 11 0,000 8,776E-03 0,01971256 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 8,776E-03 0,01969333 ! regulation of organic acid transport GO:0032890 17 11 0,000 8,776E-03 0,01967413 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 8,776E-03 0,01965497 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 8,776E-03 0,01963585 ! mRNA 3'-end processing GO:0031124 19 11 0,000 8,776E-03 0,01961677 ! lysogeny GO:0030069 18 11 0,000 8,776E-03 0,01959773 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 8,776E-03 0,01957872 ! acrosome reaction GO:0007340 13 11 0,000 8,776E-03 0,01955975 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 8,776E-03 0,01954081 ! lactation GO:0007595 20 12 0,000 9,571E-03 0,02128872 ! reproductive cellular process GO:0048610 14 12 0,000 9,571E-03 0,02126815 ! tRNA modification GO:0006400 14 12 0,000 9,571E-03 0,02124762 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 9,571E-03 0,02122713 ! positive regulation of blood pressure GO:0045777 16 12 0,000 9,571E-03 0,02120668 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 9,571E-03 0,02118627 ! 'de novo' protein folding GO:0006458 18 12 0,000 9,571E-03 0,0211659 ! dicarboxylic acid transport GO:0006835 22 12 0,000 9,571E-03 0,02114557 ! non-recombinational repair GO:0000726 19 12 0,000 9,571E-03 0,02112528 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 9,571E-03 0,02110502 ! peroxisomal transport GO:0043574 21 12 0,000 9,571E-03 0,02108481 ! cartilage condensation GO:0001502 18 12 0,000 9,571E-03 0,02106463 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 9,571E-03 0,02104449 ! cytokine biosynthetic process GO:0042089 16 12 0,000 9,571E-03 0,02102439 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 9,571E-03 0,02100433 ! heart looping GO:0001947 15 12 0,000 9,571E-03 0,02098431 ! palate development GO:0060021 15 12 0,000 9,571E-03 0,02096432 ! positive regulation of cell growth GO:0030307 16 12 0,000 9,571E-03 0,02094437 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 9,571E-03 0,02092447 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 9,571E-03 0,02090459 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 9,571E-03 0,02088476 ! arginine metabolic process GO:0006525 13 12 0,000 9,571E-03 0,02086496 ! glycoprotein catabolic process GO:0006516 19 12 0,000 9,571E-03 0,02084521 ! methionine metabolic process GO:0006555 13 12 0,000 9,571E-03 0,02082548 ! tyrosine metabolic process GO:0006570 14 12 0,000 9,571E-03 0,0208058 ! Golgi organization GO:0007030 18 12 0,000 9,571E-03 0,02078615 ! cell-cell junction assembly GO:0007043 18 12 0,000 9,571E-03 0,02076654 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 9,571E-03 0,02074697 ! monoamine transport GO:0015844 13 12 0,000 9,571E-03 0,02072744 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 9,571E-03 0,02070794 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 9,571E-03 0,02068847 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 9,571E-03 0,02066905 ! L-amino acid transport GO:0015807 20 12 0,000 9,571E-03 0,02064966 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 9,571E-03 0,02063031 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 9,571E-03 0,02061099 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 9,571E-03 0,02059171 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 9,571E-03 0,02057246 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 9,571E-03 0,02055326 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 9,571E-03 0,02053408 ! cerebellum development GO:0021549 13 12 0,000 9,571E-03 0,02051495 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 9,571E-03 0,02049584 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 9,571E-03 0,02047678 ! histone acetylation GO:0016573 23 12 0,000 9,571E-03 0,02045775 ! histone methylation GO:0016571 15 12 0,000 9,571E-03 0,02043875 ! autonomic nervous system development GO:0048483 23 12 0,000 9,571E-03 0,02041979 ! gland morphogenesis GO:0022612 23 12 0,000 9,571E-03 0,02040087 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 9,571E-03 0,02038198 ! peptidyl-lysine modification GO:0018205 18 12 0,000 9,571E-03 0,02036312 ! negative regulation of protein secretion GO:0050709 20 12 0,000 9,571E-03 0,0203443 ! response to gamma radiation GO:0010332 20 12 0,000 9,571E-03 0,02032552 ! regulation of epidermis development GO:0045682 17 12 0,000 9,571E-03 0,02030677 ! intestinal absorption GO:0050892 19 12 0,000 9,571E-03 0,02028805 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 9,571E-03 0,02026937 ! cAMP biosynthetic process GO:0006171 20 12 0,000 9,571E-03 0,02025072 ! regulation of mRNA stability GO:0043488 27 12 0,000 9,571E-03 0,02023211 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 9,571E-03 0,02021353 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 9,571E-03 0,02019499 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 9,571E-03 0,02017648 ! RNA 3'-end processing GO:0031123 20 12 0,000 9,571E-03 0,020158 ! microspike assembly GO:0030035 23 12 0,000 9,571E-03 0,02013956 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 9,571E-03 0,02012115 ! response to cold GO:0009409 14 12 0,000 9,571E-03 0,02010277 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 0,01036437 0,02175005 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,01036437 0,02173022 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,01036437 0,02171043 ! cGMP metabolic process GO:0046068 16 13 0,000 0,01036437 0,02169068 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,01036437 0,02167096 ! water transport GO:0006833 17 13 0,000 0,01036437 0,02165128 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,01036437 0,02163163 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,01036437 0,02161202 ! lipid localization GO:0010876 24 13 0,000 0,01036437 0,02159244 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,01036437 0,0215729 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,01036437 0,0215534 ! organelle fusion GO:0048284 28 13 0,000 0,01036437 0,02153393 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,01036437 0,02151449 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,01036437 0,02149509 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,01036437 0,02147573 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,01036437 0,0214564 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,01036437 0,0214371 ! response to hexose stimulus GO:0009746 19 13 0,000 0,01036437 0,02141784 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,01036437 0,02139861 ! glutamate metabolic process GO:0006536 18 13 0,000 0,01036437 0,02137942 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,01036437 0,02136027 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,01036437 0,02134114 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,01036437 0,02132205 ! NAD metabolic process GO:0019674 21 13 0,000 0,01036437 0,021303 ! exocrine system development GO:0035272 27 13 0,000 0,01036437 0,02128398 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,01036437 0,02126499 ! bone mineralization GO:0030282 15 13 0,000 0,01036437 0,02124604 ! regulation of exocytosis GO:0017157 17 13 0,000 0,01036437 0,02122712 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,01036437 0,02120824 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,01036437 0,02118938 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,01036437 0,02117057 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,01036437 0,02115178 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,01036437 0,02113303 ! genitalia development GO:0048806 15 13 0,000 0,01036437 0,02111431 ! regulation of cellular pH GO:0030641 20 13 0,000 0,01036437 0,02109563 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 0,01036437 0,02107697 ! cellular pigmentation GO:0033059 24 13 0,000 0,01036437 0,02105835 ! tissue regeneration GO:0042246 21 13 0,000 0,01036437 0,02103977 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,01036437 0,02102121 ! cofactor transport GO:0051181 19 13 0,000 0,01036437 0,02100269 ! NADP metabolic process GO:0006739 18 13 0,000 0,01036437 0,0209842 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,01036437 0,02096575 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,01036437 0,02094733 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,01036437 0,02092893 ! gas transport GO:0015669 18 13 0,000 0,01036437 0,02091058 ! regulation of RNA stability GO:0043487 28 13 0,000 0,01036437 0,02089225 ! heme biosynthetic process GO:0006783 20 13 0,000 0,01036437 0,02087396 ! regulation of axon extension GO:0030516 23 13 0,000 0,01036437 0,02085569 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,01036437 0,02083746 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,01036437 0,02081926 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,01036437 0,0208011 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,01036437 0,02078296 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,01036437 0,02076486 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,01036437 0,02074679 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,01115749 0,02231497 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,01115749 0,02229558 ! superoxide anion generation GO:0042554 18 14 0,000 0,01115749 0,02227623 ! neuron maturation GO:0042551 21 14 0,000 0,01115749 0,02225691 ! regulation of S phase GO:0033261 18 14 0,000 0,01115749 0,02223762 ! myotube differentiation GO:0014902 21 14 0,000 0,01115749 0,02221837 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 0,01115749 0,02219915 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,01115749 0,02217996 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,01115749 0,02216081 ! inositol metabolic process GO:0006020 20 14 0,000 0,01115749 0,02214169 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,01115749 0,0221226 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,01115749 0,02210355 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,01115749 0,02208452 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,01115749 0,02206554 ! gene silencing by RNA GO:0031047 20 14 0,000 0,01115749 0,02204658 ! response to cAMP GO:0051591 19 14 0,000 0,01115749 0,02202765 ! limbic system development GO:0021761 25 14 0,000 0,01115749 0,02200876 ! startle response GO:0001964 21 14 0,000 0,01115749 0,0219899 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,01115749 0,02197108 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,01115749 0,02195228 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,01115749 0,02193352 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,01115749 0,02191479 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,01115749 0,02189609 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,01115749 0,02187742 ! glycine metabolic process GO:0006544 22 14 0,000 0,01115749 0,02185879 ! pituitary gland development GO:0021983 23 14 0,000 0,01115749 0,02184019 ! cellular response to starvation GO:0009267 21 14 0,000 0,01115749 0,02182161 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,01115749 0,02180307 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,01115749 0,02178456 ! regulation of heart rate GO:0002027 23 14 0,000 0,01115749 0,02176609 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,01115749 0,02174764 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,01115749 0,02172923 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,01115749 0,02171084 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,01115749 0,02169249 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,01115749 0,02167417 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,01115749 0,02165588 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,01115749 0,02163762 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,01115749 0,02161939 ! axon cargo transport GO:0008088 27 14 0,000 0,01115749 0,02160119 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,01115749 0,02158303 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,01115749 0,02156489 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,01115749 0,02154678 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,01115749 0,02152871 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,01115749 0,02151066 ! mRNA splice site selection GO:0006376 26 14 0,000 0,01115749 0,02149264 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,01115749 0,02147466 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,01115749 0,0214567 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,01115749 0,02143878 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,01115749 0,02142088 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,01115749 0,02140302 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,01115749 0,02138518 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,01115749 0,02136738 ! muscle maintenance GO:0046716 19 14 0,000 0,01115749 0,0213496 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,01115749 0,02133185 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,01115749 0,02131413 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,01115749 0,02129645 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,01115749 0,02127879 ! release of cytochrome c from mitochondria GO:0001836 23 14 0,000 0,01115749 0,02126116 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,01115749 0,02124356 ! cilium assembly GO:0042384 20 14 0,000 0,01115749 0,02122599 ! peptide hormone secretion GO:0030072 23 14 0,000 0,01115749 0,02120844 ! positive regulation of cell size GO:0045793 20 15 0,000 0,01195001 0,02269614 ! metencephalon development GO:0022037 19 15 0,000 0,01195001 0,02267741 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,01195001 0,02265871 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,01195001 0,02264005 ! skin development GO:0043588 25 15 0,000 0,01195001 0,02262142 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,01195001 0,02260281 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,01195001 0,02258424 ! lipid phosphorylation GO:0046834 23 15 0,000 0,01195001 0,0225657 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,01195001 0,02254719 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,01195001 0,02252871 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,01195001 0,02251025 ! bile acid metabolic process GO:0008206 22 15 0,000 0,01195001 0,02249183 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,01195001 0,02247344 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,01195001 0,02245508 ! adult walking behavior GO:0007628 25 15 0,000 0,01195001 0,02243675 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,01195001 0,02241845 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,01195001 0,02240018 ! myoblast differentiation GO:0045445 27 15 0,000 0,01195001 0,02238194 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,01195001 0,02236373 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,01195001 0,02234555 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,01195001 0,02232739 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,01195001 0,02230927 ! cerebral cortex development GO:0021987 29 15 0,000 0,01195001 0,02229118 ! response to osmotic stress GO:0006970 22 15 0,000 0,01195001 0,02227311 ! vesicle coating GO:0006901 25 15 0,000 0,01195001 0,02225508 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,01195001 0,02223707 ! DNA integration GO:0015074 22 15 0,000 0,01195001 0,0222191 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,01195001 0,02220115 ! peptide secretion GO:0002790 27 15 0,000 0,01195001 0,02218323 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,01195001 0,02216534 ! regulation of vasodilation GO:0042312 24 15 0,000 0,01195001 0,02214748 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,01195001 0,02212965 ! neuron recognition GO:0008038 22 15 0,000 0,01195001 0,02211184 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,01195001 0,02209407 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,01195001 0,02207632 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,01195001 0,0220586 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,01195001 0,02204091 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,01195001 0,02202325 ! biomineral formation GO:0031214 18 15 0,000 0,01195001 0,02200562 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,01195001 0,02198802 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,01195001 0,02197044 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,01195001 0,02195289 ! dopamine metabolic process GO:0042417 30 15 0,000 0,01195001 0,02193537 ! organic cation transport GO:0015695 19 15 0,000 0,01195001 0,02191788 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,01195001 0,02190042 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,01195001 0,02188298 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,01195001 0,02186557 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,01195001 0,02184819 ! defense response to virus GO:0051607 27 15 0,000 0,01195001 0,02183083 ! peptide hormone processing GO:0016486 19 15 0,000 0,01195001 0,02181351 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,01195001 0,02179621 ! protein secretion GO:0009306 27 16 0,000 0,01274194 0,02322224 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,01274194 0,02320385 ! hormone secretion GO:0046879 25 16 0,000 0,01274194 0,0231855 ! bone remodeling GO:0046849 24 16 0,000 0,01274194 0,02316717 ! endothelial cell migration GO:0043542 22 16 0,000 0,01274194 0,02314887 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,01274194 0,0231306 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,01274194 0,02311236 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,01274194 0,02309414 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,01274194 0,02307596 ! glial cell development GO:0021782 24 16 0,000 0,01274194 0,0230578 ! patterning of blood vessels GO:0001569 24 16 0,000 0,01274194 0,02303968 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,01274194 0,02302158 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,01274194 0,02300351 ! protein polyubiquitination GO:0000209 26 16 0,000 0,01274194 0,02298546 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,01274194 0,02296745 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,01274194 0,02294947 ! fructose metabolic process GO:0006000 20 16 0,000 0,01274194 0,02293151 ! regulation of protein binding GO:0043393 27 16 0,000 0,01274194 0,02291358 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,01274194 0,02289568 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,01274194 0,0228778 ! protein export from nucleus GO:0006611 24 16 0,000 0,01274194 0,02285996 ! negative regulation of immune response GO:0050777 28 16 0,000 0,01274194 0,02284214 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,01274194 0,02282435 ! DNA replication initiation GO:0006270 25 16 0,000 0,01274194 0,02280659 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,01274194 0,02278886 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,01274194 0,02277115 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,01274194 0,02275347 ! diencephalon development GO:0021536 25 16 0,000 0,01274194 0,02273582 ! oogenesis GO:0048477 23 16 0,000 0,01274194 0,02271819 ! neural crest cell migration GO:0001755 24 16 0,000 0,01274194 0,02270059 ! G1 phase GO:0051318 27 16 0,000 0,01274194 0,02268302 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,01274194 0,02266548 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,01274194 0,02264797 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,01274194 0,02263048 ! steroid catabolic process GO:0006706 22 16 0,000 0,01274194 0,02261302 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,01274194 0,02259558 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,01274194 0,02257817 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,01274194 0,02256079 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,01274194 0,02254344 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,01274194 0,02252611 ! sperm-egg recognition GO:0035036 16 16 0,000 0,01274194 0,02250881 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,01274194 0,02249153 ! nerve development GO:0021675 18 16 0,000 0,01274194 0,02247428 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,01274194 0,02245706 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,01274194 0,02243987 ! negative regulation of translation GO:0017148 22 16 0,000 0,01274194 0,0224227 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,01353329 0,02379706 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,01353329 0,02377888 ! negative regulation of defense response GO:0031348 19 17 0,000 0,01353329 0,02376073 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,01353329 0,02374261 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,01353329 0,02372451 ! glycerol metabolic process GO:0006071 20 17 0,000 0,01353329 0,02370644 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,01353329 0,0236884 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,01353329 0,02367039 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,01353329 0,0236524 ! signal complex assembly GO:0007172 29 17 0,000 0,01353329 0,02363444 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,01353329 0,02361651 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,01353329 0,0235986 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,01353329 0,02358073 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,01353329 0,02356288 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,01353329 0,02354505 ! memory GO:0007613 25 17 0,000 0,01353329 0,02352726 ! keratinization GO:0031424 17 17 0,000 0,01353329 0,02350949 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,01353329 0,02349174 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,01353329 0,02347403 ! retinoid metabolic process GO:0001523 22 17 0,000 0,01353329 0,02345634 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,01353329 0,02343867 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,01353329 0,02342104 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,01353329 0,02340343 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,01353329 0,02338584 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,01353329 0,02336829 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,01353329 0,02335076 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 0,000 0,01353329 0,02333325 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,01353329 0,02331577 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,01353329 0,02329832 ! membrane budding GO:0006900 29 17 0,000 0,01353329 0,0232809 ! heme metabolic process GO:0042168 27 17 0,000 0,01353329 0,0232635 ! actin filament bundle formation GO:0051017 26 17 0,000 0,01353329 0,02324612 ! neuromuscular junction development GO:0007528 23 17 0,000 0,01353329 0,02322878 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,01353329 0,02321145 ! body fluid secretion GO:0007589 27 17 0,000 0,01353329 0,02319416 ! stem cell differentiation GO:0048863 36 17 0,000 0,01353329 0,02317689 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,01353329 0,02315964 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,01353329 0,02314242 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,01353329 0,02312523 ! sensory perception of pain GO:0019233 23 17 0,000 0,01353329 0,02310806 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,01353329 0,02309092 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,01353329 0,0230738 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,01353329 0,02305671 ! synaptogenesis GO:0007416 24 17 0,000 0,01353329 0,02303964 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,01353329 0,0230226 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,01353329 0,02300559 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,01353329 0,0229886 ! cell-cell junction organization GO:0045216 25 17 0,000 0,01353329 0,02297163 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,01353329 0,02295469 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,01353329 0,02293777 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,01353329 0,02292088 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,01353329 0,02290402 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,01353329 0,02288718 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,01353329 0,02287036 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,01432404 0,02418891 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,01432404 0,02417116 ! positive regulation of translation GO:0045727 28 18 0,000 0,01432404 0,02415344 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,01432404 0,02413575 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,01432404 0,02411808 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,01432404 0,02410044 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,01432404 0,02408282 ! cAMP metabolic process GO:0046058 33 18 0,000 0,01432404 0,02406523 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,01432404 0,02404766 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,01432404 0,02403012 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,01432404 0,02401261 ! axis specification GO:0009798 26 18 0,000 0,01432404 0,02399512 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,01432404 0,02397765 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,01432404 0,02396021 ! pancreas development GO:0031016 26 18 0,000 0,01432404 0,0239428 ! apoptotic mitochondrial changes GO:0008637 29 18 0,000 0,01432404 0,02392541 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,01432404 0,02390805 ! glutamine metabolic process GO:0006541 23 18 0,000 0,01432404 0,02389071 ! response to retinoic acid GO:0032526 25 18 0,000 0,01432404 0,0238734 ! pigmentation during development GO:0048066 31 18 0,000 0,01432404 0,02385612 ! central nervous system neuron development GO:0021954 30 18 0,000 0,01432404 0,02383885 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,01432404 0,02382162 ! fucose metabolic process GO:0006004 26 18 0,000 0,01432404 0,0238044 ! response to fungus GO:0009620 19 18 0,000 0,01432404 0,02378722 ! peptide cross-linking GO:0018149 31 18 0,000 0,01432404 0,02377005 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,01432404 0,02375292 ! heart process GO:0003015 27 18 0,000 0,01432404 0,0237358 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,01432404 0,02371871 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,01432404 0,02370165 ! visual learning GO:0008542 35 18 0,000 0,01432404 0,02368461 ! somitogenesis GO:0001756 24 18 0,000 0,01432404 0,0236676 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,01432404 0,02365061 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,01432404 0,02363364 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,01432404 0,0236167 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,01432404 0,02359978 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,01432404 0,02358289 ! vitamin transport GO:0051180 24 18 0,000 0,01432404 0,02356602 ! hormone transport GO:0009914 27 18 0,000 0,01432404 0,02354917 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,01432404 0,02353235 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,01432404 0,02351556 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,01432404 0,02349878 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,01432404 0,02348203 ! cell-cell recognition GO:0009988 20 18 0,000 0,01432404 0,02346531 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,01432404 0,02344861 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,01432404 0,02343193 ! regulation of glucose import GO:0046324 21 18 0,000 0,01432404 0,02341528 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,01432404 0,02339865 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,01432404 0,02338204 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,01432404 0,02336546 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,01432404 0,0233489 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,01511421 0,02461946 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,01511421 0,02460204 ! positive regulation of fibroblast proliferation GO:0048146 27 19 0,000 0,01511421 0,02458464 ! positive regulation of ossification GO:0045778 30 19 0,000 0,01511421 0,02456726 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,01511421 0,02454991 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,01511421 0,02453259 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,01511421 0,02451529 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,01511421 0,02449801 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,01511421 0,02448076 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,01511421 0,02446353 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,01511421 0,02444633 ! regeneration GO:0031099 32 19 0,000 0,01511421 0,02442915 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,01511421 0,02441199 ! response to alkaloid GO:0043279 32 19 0,000 0,01511421 0,02439486 ! sensory perception of taste GO:0050909 23 19 0,000 0,01511421 0,02437775 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,01511421 0,02436067 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 0,000 0,01511421 0,02434361 ! smooth muscle contraction GO:0006939 36 19 0,000 0,01511421 0,02432658 ! peroxisome organization GO:0007031 29 19 0,000 0,01511421 0,02430956 ! digestive system process GO:0022600 30 19 0,000 0,01511421 0,02429258 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,01511421 0,02427561 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,01511421 0,02425867 ! response to vitamin A GO:0033189 26 19 0,000 0,01511421 0,02424176 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,01511421 0,02422486 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,01511421 0,02420799 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,01511421 0,02419115 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,01511421 0,02417432 ! response to starvation GO:0042594 30 19 0,000 0,01511421 0,02415752 ! sex determination GO:0007530 29 19 0,000 0,01511421 0,02414075 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,01511421 0,024124 ! plasma membrane fusion GO:0045026 23 19 0,000 0,01511421 0,02410727 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,01511421 0,02409056 ! cytolysis GO:0019835 20 19 0,000 0,01511421 0,02407388 ! renal system process GO:0003014 35 19 0,000 0,01511421 0,02405722 ! vasodilation GO:0042311 33 19 0,000 0,01511421 0,02404058 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,01511421 0,02402396 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,01511421 0,02400737 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,01511421 0,02399081 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,01511421 0,02397426 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,01511421 0,02395774 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,01511421 0,02394124 ! sarcomere organization GO:0045214 23 19 0,000 0,01511421 0,02392476 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,01511421 0,02390831 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,01511421 0,02389187 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,01511421 0,02387547 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,01511421 0,02385908 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,01511421 0,02384271 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,01511421 0,02382637 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,01511421 0,02381005 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,01511421 0,02379376 ! protein stabilization GO:0050821 26 19 0,000 0,01511421 0,02377748 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,01590379 0,02500253 ! iron ion transport GO:0006826 37 20 0,000 0,01590379 0,02498546 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,01590379 0,0249684 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,01590379 0,02495137 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,01590379 0,02493436 ! response to vitamin GO:0033273 29 20 0,000 0,01590379 0,02491738 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,01590379 0,02490041 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,01590379 0,02488347 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,01590379 0,02486656 ! spinal cord development GO:0021510 31 20 0,000 0,01590379 0,02484966 ! response to ethanol GO:0045471 37 20 0,000 0,01590379 0,02483279 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,01590379 0,02481595 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 0,000 0,01590379 0,02479912 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,01590379 0,02478232 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,01590379 0,02476554 ! chromosome condensation GO:0030261 31 20 0,000 0,01590379 0,02474879 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,01590379 0,02473205 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,01590379 0,02471534 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,01590379 0,02469865 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,01590379 0,02468199 ! pallium development GO:0021543 38 20 0,000 0,01590379 0,02466535 ! DNA modification GO:0006304 28 20 0,000 0,01590379 0,02464872 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,01590379 0,02463213 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,01590379 0,02461555 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,01590379 0,024599 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,01590379 0,02458246 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,01590379 0,02456595 ! positive regulation of B cell activation GO:0050871 31 20 0,000 0,01590379 0,02454947 ! collagen catabolic process GO:0030574 25 20 0,000 0,01590379 0,024533 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,01590379 0,02451656 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,01590379 0,02450014 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,01590379 0,02448374 ! alditol metabolic process GO:0019400 24 20 0,000 0,01590379 0,02446736 ! actin filament-based movement GO:0030048 34 20 0,000 0,01590379 0,02445101 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,01669278 0,02564688 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,01669278 0,02562976 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,01669278 0,02561266 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,01669278 0,02559559 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,01669278 0,02557854 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,01669278 0,02556151 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,01669278 0,0255445 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,01669278 0,02552752 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,01669278 0,02551055 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,01669278 0,02549361 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,01669278 0,0254767 ! protein amino acid acylation GO:0043543 37 21 0,000 0,01669278 0,0254598 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,01669278 0,02544293 ! vesicle docking GO:0048278 27 21 0,000 0,01669278 0,02542608 ! phototransduction GO:0007602 25 21 0,000 0,01669278 0,02540925 ! dendrite development GO:0016358 35 21 0,000 0,01669278 0,02539245 ! visual behavior GO:0007632 39 21 0,000 0,01669278 0,02537567 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,01669278 0,02535891 ! ovarian follicle development GO:0001541 30 21 0,000 0,01669278 0,02534217 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,01669278 0,02532545 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,01669278 0,02530876 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,01669278 0,02529208 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,01669278 0,02527543 ! cell aging GO:0007569 32 21 0,000 0,01669278 0,02525881 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,01669278 0,0252422 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,01669278 0,02522561 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,01669278 0,02520905 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,01669278 0,02519251 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,01669278 0,02517599 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,01669278 0,02515949 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,01669278 0,02514302 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,01669278 0,02512656 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,01669278 0,02511013 ! fatty acid transport GO:0015908 30 21 0,000 0,01669278 0,02509372 ! immunoglobulin production GO:0002377 33 21 0,000 0,01669278 0,02507732 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,01669278 0,02506096 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,01669278 0,02504461 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,01669278 0,02502828 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,01669278 0,02501198 ! cellular response to extracellular stimulus GO:0031668 32 21 0,000 0,01669278 0,02499569 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,01669278 0,02497943 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,01669278 0,02496319 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,01669278 0,02494697 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,01669278 0,02493077 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,01669278 0,02491459 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,01669278 0,02489843 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,01669278 0,0248823 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,01669278 0,02486618 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,01669278 0,02485009 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,01669278 0,02483401 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,01748118 0,02599012 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,01748118 0,02597333 ! regulation of fibroblast proliferation GO:0048145 35 22 0,000 0,01748118 0,02595656 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,01748118 0,02593981 ! viral genome replication GO:0019079 29 22 0,000 0,01748118 0,02592309 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,01748118 0,02590639 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,01748118 0,0258897 ! leukocyte adhesion GO:0007159 38 22 0,000 0,01748118 0,02587304 ! molting cycle process GO:0022404 40 22 0,000 0,01748118 0,02585641 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,01748118 0,02583979 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,01748118 0,02582319 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,01748118 0,02580662 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,01748118 0,02579006 ! vasculogenesis GO:0001570 33 22 0,000 0,01748118 0,02577353 ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,01748118 0,02575702 GO:0010810|regulation of cell-substrate adhesion, ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,01748118 0,02574053 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,01748118 0,02572406 ! lysosome organization GO:0007040 37 22 0,000 0,01748118 0,02570762 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,01748118 0,02569119 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,01748118 0,02567478 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,01748118 0,0256584 ! regulation of behavior GO:0050795 38 22 0,000 0,01748118 0,02564203 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,01748118 0,02562569 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,01748118 0,02560937 ! membrane depolarization GO:0051899 35 22 0,000 0,01748118 0,02559307 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,01748118 0,02557679 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,01748118 0,02556053 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,01748118 0,02554429 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,01748118 0,02552807 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,01748118 0,02551187 ! blastocyst development GO:0001824 37 22 0,000 0,01748118 0,02549569 ! neural tube closure GO:0001843 33 22 0,000 0,01748118 0,02547954 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,01748118 0,0254634 ! protein tetramerization GO:0051262 39 22 0,000 0,01748118 0,02544729 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,01826899 0,02657728 ! neuron fate commitment GO:0048663 32 23 0,000 0,01826899 0,02656048 ! embryonic pattern specification GO:0009880 31 23 0,000 0,01826899 0,02654371 ! positive regulation of cell adhesion GO:0045785 37 23 0,000 0,01826899 0,02652695 ! myelination GO:0042552 35 23 0,000 0,01826899 0,02651021 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,01826899 0,0264935 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,01826899 0,0264768 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,01826899 0,02646013 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,01826899 0,02644348 ! vesicle targeting GO:0006903 32 23 0,000 0,01826899 0,02642685 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,01826899 0,02641024 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,01826899 0,02639365 ! osteoblast differentiation GO:0001649 40 23 0,000 0,01826899 0,02637708 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,01826899 0,02636053 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,01826899 0,026344 ! interaction with host GO:0051701 37 23 0,000 0,01826899 0,0263275 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,01826899 0,02631101 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,01826899 0,02629455 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,01826899 0,0262781 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,01826899 0,02626168 ! negative regulation of phosphorylation GO:0042326 41 23 0,000 0,01826899 0,02624528 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,01826899 0,02622889 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,01826899 0,02621253 ! cell fate determination GO:0001709 45 23 0,000 0,01826899 0,02619619 ! pentose metabolic process GO:0019321 31 23 0,000 0,01826899 0,02617987 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,01826899 0,02616357 ! spermatid development GO:0007286 33 23 0,000 0,01826899 0,02614728 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,01826899 0,02613102 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,01826899 0,02611478 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,01826899 0,02609856 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,01826899 0,02608236 ! telomere organization GO:0032200 32 23 0,000 0,01826899 0,02606618 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,01826899 0,02605002 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,01826899 0,02603388 ! regulation of amine transport GO:0051952 38 23 0,000 0,01826899 0,02601776 ! liver development GO:0001889 40 23 0,000 0,01826899 0,02600166 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,01905622 0,02710533 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,01905622 0,02708857 ! initiation of viral infection GO:0019059 42 24 0,000 0,01905622 0,02707184 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,01905622 0,02705513 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,01905622 0,02703844 ! superoxide metabolic process GO:0006801 32 24 0,000 0,01905622 0,02702177 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,01905622 0,02700512 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! insulin receptor signaling pathway GO:0008286 40 24 0,000 0,01905622 0,02698849 ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,01905622 0,02697189 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,01905622 0,0269553 ! sperm motility GO:0030317 27 24 0,000 0,01905622 0,02693873 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,01905622 0,02692218 ! vacuole organization GO:0007033 39 24 0,000 0,01905622 0,02690566 ! receptor metabolic process GO:0043112 37 24 0,000 0,01905622 0,02688915 ! neural crest cell development GO:0014032 39 24 0,000 0,01905622 0,02687266 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,01905622 0,0268562 ! primary neural tube formation GO:0014020 35 24 0,000 0,01905622 0,02683975 ! negative regulation of cell development GO:0010721 56 24 0,000 0,01905622 0,02682333 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,01905622 0,02680692 ! base-excision repair GO:0006284 31 24 0,000 0,01905622 0,02679053 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,01905622 0,02677417 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,01905622 0,02675782 ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,01905622 0,0267415 ! glutathione metabolic process GO:0006749 29 24 0,000 0,01905622 0,02672519 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,01905622 0,02670891 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,01905622 0,02669264 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,01905622 0,02667639 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,01984287 0,0277607 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,01984287 0,02774383 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,01984287 0,02772697 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,01984287 0,02771014 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,01984287 0,02769332 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,01984287 0,02767653 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 0,000 0,01984287 0,02765975 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 43 25 0,000 0,01984287 0,027643 ! male gonad development GO:0008584 33 25 0,000 0,01984287 0,02762627 ! iron ion homeostasis GO:0055072 39 25 0,000 0,01984287 0,02760955 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,01984287 0,02759286 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,01984287 0,02757619 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,01984287 0,02755954 ! phospholipid transport GO:0015914 35 25 0,000 0,01984287 0,0275429 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,01984287 0,02752629 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,01984287 0,0275097 ! detection of light stimulus GO:0009583 30 25 0,000 0,01984287 0,02749313 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,01984287 0,02747658 GO:0045840|positive regulation of mitosis, ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,01984287 0,02746004 ! leukocyte proliferation GO:0070661 39 25 0,000 0,01984287 0,02744353 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,01984287 0,02742704 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,02062892 0,02849641 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,02062892 0,02847931 ! translational initiation GO:0006413 43 26 0,000 0,02062892 0,02846222 ! regulation of pH GO:0006885 36 26 0,000 0,02062892 0,02844516 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 0,000 0,02062892 0,02842812 ! circadian rhythm GO:0007623 42 26 0,000 0,02062892 0,02841109 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,02062892 0,02839409 ! post-embryonic development GO:0009791 42 26 0,000 0,02062892 0,02837711 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,02062892 0,02836015 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,02062892 0,0283432 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,02062892 0,02832628 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,02062892 0,02830938 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,02062892 0,0282925 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,02062892 0,02827564 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,02062892 0,0282588 ! regulation of coagulation GO:0050818 39 26 0,000 0,02062892 0,02824198 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,0214144 0,02929989 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,0214144 0,02928247 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,0214144 0,02926507 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,0214144 0,02924769 ! membrane docking GO:0022406 39 27 0,000 0,0214144 0,02923033 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,0214144 0,02921299 ! catechol metabolic process GO:0009712 43 27 0,000 0,0214144 0,02919568 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,0214144 0,02917838 ! acute-phase response GO:0006953 42 27 0,000 0,0214144 0,02916111 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,0214144 0,02914385 ! myofibril assembly GO:0030239 36 27 0,000 0,0214144 0,02912662 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,0214144 0,0291094 ! response to ionizing radiation GO:0010212 47 27 0,000 0,0214144 0,02909221 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,0214144 0,02907504 ! natural killer cell activation GO:0030101 35 27 0,000 0,0214144 0,02905788 ! lipid oxidation GO:0034440 38 27 0,000 0,0214144 0,02904075 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,0214144 0,02902364 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,0214144 0,02900654 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,0214144 0,02898947 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,0214144 0,02897242 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,0214144 0,02895538 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,0214144 0,02893837 ! gene silencing GO:0016458 41 27 0,000 0,0214144 0,02892138 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,02219928 0,02996382 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,02219928 0,02994625 ! phenol metabolic process GO:0018958 44 28 0,000 0,02219928 0,02992869 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,02219928 0,02991116 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,02219928 0,02989365 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,02219928 0,02987615 ! cell junction assembly GO:0034329 56 28 0,000 0,02219928 0,02985868 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,02219928 0,02984123 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,02219928 0,0298238 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,02219928 0,02980639 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,02219928 0,029789 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,02219928 0,02977163 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,02219928 0,02975428 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,02219928 0,02973695 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,02219928 0,02971964 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,02219928 0,02970236 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,02219928 0,02968509 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,02219928 0,02966784 ! mesoderm formation GO:0001707 46 28 0,000 0,02219928 0,02965061 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,02219928 0,0296334 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,02219928 0,02961621 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,02219928 0,02959904 ! ensheathment of neurons GO:0007272 43 28 0,000 0,02219928 0,02958189 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,02219928 0,02956476 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,02219928 0,02954766 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,02219928 0,02953057 ! neural tube formation GO:0001841 41 28 0,000 0,02219928 0,0295135 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,02219928 0,02949645 ! placenta development GO:0001890 37 28 0,000 0,02219928 0,02947942 ! regulation of B cell activation GO:0050864 42 28 0,000 0,02219928 0,02946241 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,02298358 0,03048572 ! regulation of innate immune response GO:0045088 38 29 0,000 0,02298358 0,03046815 ! ovulation cycle process GO:0022602 41 29 0,000 0,02298358 0,0304506 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,02298358 0,03043307 ! protein targeting to membrane GO:0006612 53 29 0,000 0,02298358 0,03041556 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,02298358 0,03039807 ! mismatch repair GO:0006298 34 29 0,000 0,02298358 0,0303806 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,02298358 0,03036315 ! muscle cell development GO:0055001 38 29 0,000 0,02298358 0,03034572 ! formation of primary germ layer GO:0001704 48 29 0,000 0,02298358 0,03032831 ! telencephalon development GO:0021537 52 29 0,000 0,02298358 0,03031092 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,02298358 0,03029355 ! eye morphogenesis GO:0048592 51 29 0,000 0,02298358 0,0302762 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,02298358 0,03025887 ! tissue homeostasis GO:0001894 42 29 0,000 0,02298358 0,03024156 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,0237673 0,03125489 ! collagen metabolic process GO:0032963 40 30 0,000 0,0237673 0,03123703 ! organic anion transport GO:0015711 51 30 0,000 0,0237673 0,03121919 ! cholesterol transport GO:0030301 46 30 0,000 0,0237673 0,03120137 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,0237673 0,03118357 ! spliceosome assembly GO:0000245 49 30 0,000 0,0237673 0,03116579 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,0237673 0,03114803 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,0237673 0,03113029 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,0237673 0,03111258 ! ceramide metabolic process GO:0006672 43 30 0,000 0,0237673 0,03109488 ! ovulation cycle GO:0042698 43 30 0,000 0,0237673 0,0310772 ! hindbrain development GO:0030902 45 30 0,000 0,0237673 0,03105954 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,0237673 0,03104191 ! adult locomotory behavior GO:0008344 47 30 0,000 0,0237673 0,03102429 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,0237673 0,03100669 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,0237673 0,03098911 ! response to heat GO:0009408 41 30 0,000 0,0237673 0,03097156 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,0237673 0,03095402 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,0237673 0,0309365 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,02455044 0,03193778 ! negative regulation of secretion GO:0051048 49 31 0,000 0,02455044 0,03191973 ! mammary gland development GO:0030879 57 31 0,000 0,02455044 0,0319017 ! glial cell differentiation GO:0010001 55 31 0,000 0,02455044 0,03188368 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,02455044 0,03186569 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,02455044 0,03184772 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,02455044 0,03182977 ! odontogenesis GO:0042476 50 31 0,000 0,02455044 0,03181183 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,02455044 0,03179392 ! segmentation GO:0035282 41 31 0,000 0,02455044 0,03177603 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,02455044 0,03175816 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,02455044 0,03174031 ! metanephros development GO:0001656 58 31 0,000 0,02455044 0,03172247 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,02455044 0,03170466 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,02455044 0,03168687 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,02455044 0,0316691 ! cell fate specification GO:0001708 37 31 0,000 0,02455044 0,03165135 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,02455044 0,03163362 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,02455044 0,0316159 ! RNA modification GO:0009451 40 31 0,000 0,02455044 0,03159821 ! regulation of muscle development GO:0048634 48 32 0,000 0,02533299 0,03258718 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,02533299 0,03256896 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,02533299 0,03255077 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,02533299 0,03253259 ! meiosis I GO:0007127 52 32 0,000 0,02533299 0,03251444 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,02533299 0,0324963 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,02533299 0,03247819 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,02533299 0,0324601 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,02533299 0,03244202 ! peripheral nervous system development GO:0007422 53 32 0,000 0,02533299 0,03242397 ! regulation of protein stability GO:0031647 48 32 0,000 0,02533299 0,03240593 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,02533299 0,03238792 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,02533299 0,03236993 ! cytokine production GO:0001816 44 32 0,000 0,02533299 0,03235195 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,02533299 0,032334 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,02533299 0,03231607 ! vesicle localization GO:0051648 47 32 0,000 0,02533299 0,03229815 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,02611496 0,03327667 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,02611496 0,03325825 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,02611496 0,03323984 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,02611496 0,03322146 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,02611496 0,03320309 ! sister chromatid segregation GO:0000819 46 33 0,000 0,02611496 0,03318475 ! ear morphogenesis GO:0042471 42 33 0,000 0,02611496 0,03316643 ! actomyosin structure organization GO:0031032 43 33 0,000 0,02611496 0,03314812 ! cell junction organization GO:0034330 63 33 0,000 0,02611496 0,03312984 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,02611496 0,03311157 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,02611496 0,03309333 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,02611496 0,03307511 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 0,000 0,02611496 0,03305691 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,02611496 0,03303872 ! female gonad development GO:0008585 49 33 0,000 0,02611496 0,03302056 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,02611496 0,03300242 ! positive regulation of cell development GO:0010720 54 33 0,000 0,02611496 0,03298429 ! lipid homeostasis GO:0055088 55 33 0,000 0,02611496 0,03296619 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,02611496 0,03294811 ! regulation of proteolysis GO:0030162 50 33 0,000 0,02611496 0,03293004 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,02611496 0,032912 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,02611496 0,03289397 ! cytokinesis GO:0000910 52 33 0,000 0,02611496 0,03287597 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,02611496 0,03285799 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,02689634 0,03382263 ! mRNA catabolic process GO:0006402 48 34 0,000 0,02689634 0,03380414 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,02689634 0,03378568 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,02689634 0,03376724 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,02689634 0,03374882 ! feeding behavior GO:0007631 45 34 0,000 0,02689634 0,03373042 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,02689634 0,03371203 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,02689634 0,03369367 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,02689634 0,03367533 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,02689634 0,03365701 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,02689634 0,03363871 ! neuron migration GO:0001764 46 34 0,000 0,02689634 0,03362043 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,02689634 0,03360216 ! female gamete generation GO:0007292 43 34 0,000 0,02689634 0,03358392 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,02689634 0,0335657 ! polyol metabolic process GO:0019751 44 34 0,000 0,02689634 0,0335475 ! aerobic respiration GO:0009060 47 34 0,000 0,02689634 0,03352931 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,02689634 0,03351115 ! cellular response to insulin stimulus GO:0032869 52 34 0,000 0,02689634 0,03349301 ! embryonic organ development GO:0048568 45 34 0,000 0,02689634 0,03347488 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,02689634 0,03345678 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,02767714 0,03440942 ! Notch signaling pathway GO:0007219 56 35 0,000 0,02767714 0,03439083 ! regulation of intracellular protein transport GO:0033157 59 35 0,000 0,02767714 0,03437226 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,02767714 0,03435371 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,02767714 0,03433518 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,02767714 0,03431667 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,02767714 0,03429818 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,02767714 0,03427971 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,02767714 0,03426126 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,02767714 0,03424283 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,02767714 0,03422442 ! glycogen metabolic process GO:0005977 48 35 0,000 0,02767714 0,03420603 ! pigment metabolic process GO:0042440 61 35 0,000 0,02767714 0,03418766 ! positive regulation of leukocyte proliferation GO:0070665 50 35 0,000 0,02767714 0,03416931 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! protein homooligomerization GO:0051260 52 35 0,000 0,02767714 0,03415098 ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,02845736 0,03509487 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 0,000 0,02845736 0,03507607 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,02845736 0,03505728 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,02845736 0,03503851 ! negative regulation of binding GO:0051100 58 36 0,000 0,02845736 0,03501976 ! organic ether metabolic process GO:0018904 46 36 0,000 0,02845736 0,03500104 ! tissue remodeling GO:0048771 62 36 0,000 0,02845736 0,03498233 ! neural tube development GO:0021915 50 36 0,000 0,02845736 0,03496364 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,02845736 0,03494498 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,02845736 0,03492633 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,02845736 0,0349077 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,02845736 0,03488909 ! glucan metabolic process GO:0044042 49 36 0,000 0,02845736 0,03487051 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,029237 0,03580677 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,029237 0,03578771 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,029237 0,03576868 ! learning GO:0007612 67 37 0,000 0,029237 0,03574966 ! ion transmembrane transport GO:0034220 56 37 0,000 0,029237 0,03573066 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,029237 0,03571169 ! regulation of protein secretion GO:0050708 51 37 0,000 0,029237 0,03569273 ! amino acid activation GO:0043038 52 37 0,000 0,029237 0,0356738 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,029237 0,03565488 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,03001606 0,03658556 ! gliogenesis GO:0042063 71 38 0,000 0,03001606 0,03656618 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,03001606 0,03654682 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,03001606 0,03652748 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,03001606 0,03650817 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,03001606 0,03648887 ! phagocytosis GO:0006909 60 38 0,000 0,03001606 0,0364696 ! mesenchymal cell development GO:0014031 64 38 0,000 0,03001606 0,03645034 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 0,000 0,03001606 0,03643111 ! maintenance of location in cell GO:0051651 69 38 0,000 0,03001606 0,03641189 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,03079454 0,03733656 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,03079454 0,03731688 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,03079454 0,03729723 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,03079454 0,0372776 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,03079454 0,03725799 ! regulation of epithelial cell proliferation GO:0050678 71 39 0,000 0,03079454 0,0372384 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,03079454 0,03721884 ! male sex differentiation GO:0046661 53 39 0,000 0,03079454 0,03719929 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,03079454 0,03717976 ! chromatin remodeling GO:0006338 68 39 0,000 0,03079454 0,03716025 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,03079454 0,03714077 ! JNK cascade GO:0007254 54 39 0,000 0,03079454 0,0371213 ! developmental growth GO:0048589 62 39 0,000 0,03079454 0,03710186 ! cell growth GO:0016049 61 39 0,000 0,03079454 0,03708243 ! synapse organization GO:0050808 55 39 0,000 0,03079454 0,03706303 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,03157244 0,0379794 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,03157244 0,03795955 ! regulation of tube size GO:0035150 60 40 0,000 0,03157244 0,03793971 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,03157244 0,0379199 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,03157244 0,03790011 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,03157244 0,03788034 ! peptide metabolic process GO:0006518 56 40 0,000 0,03157244 0,03786059 ! inner ear development GO:0048839 57 40 0,000 0,03157244 0,03784086 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,03157244 0,03782115 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,03157244 0,03780146 ! B cell differentiation GO:0030183 62 40 0,000 0,03157244 0,0377818 ! epidermal cell differentiation GO:0009913 53 40 0,000 0,03157244 0,03776215 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,03157244 0,03774252 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,03157244 0,03772291 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,03157244 0,03770333 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,03234976 0,03861154 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,03234976 0,03859152 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,03234976 0,03857151 ! glucose transport GO:0015758 52 41 0,000 0,03234976 0,03855152 ! endosome transport GO:0016197 71 41 0,000 0,03234976 0,03853156 ! striated muscle contraction GO:0006941 62 41 0,000 0,03234976 0,03851162 ! positive regulation of DNA binding GO:0043388 57 41 0,000 0,03234976 0,03849169 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,03234976 0,03847179 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,03234976 0,03845191 ! biopolymer methylation GO:0043414 62 41 0,000 0,03234976 0,03843205 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,03234976 0,03841221 ! mitochondrial transport GO:0006839 60 42 0,000 0,0331265 0,03931421 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,0331265 0,03929394 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 0,000 0,0331265 0,03927368 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,0331265 0,03925345 ! cellular component disassembly GO:0022411 64 42 0,000 0,0331265 0,03923324 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,0331265 0,03921304 ! hexose transport GO:0008645 54 42 0,000 0,0331265 0,03919287 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,0331265 0,03917272 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,0331265 0,03915259 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,0331265 0,03913248 ! excretion GO:0007588 63 42 0,000 0,0331265 0,03911239 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,0331265 0,03909233 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,0331265 0,03907228 ! regulation of cell shape GO:0008360 78 42 0,000 0,0331265 0,03905225 ! positive regulation of binding GO:0051099 59 43 0,000 0,03390266 0,03994678 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,03390266 0,03992632 ! leukocyte migration GO:0050900 60 43 0,000 0,03390266 0,03990589 ! neuromuscular process GO:0050905 79 43 0,000 0,03390266 0,03988548 ! activation of caspase activity GO:0006919 65 43 0,000 0,03390266 0,03986509 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,03390266 0,03984472 ! tRNA processing GO:0008033 49 43 0,000 0,03390266 0,03982437 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,03390266 0,03980404 ! vesicle organization GO:0016050 79 43 0,000 0,03390266 0,03978373 ! response to insulin stimulus GO:0032868 63 43 0,000 0,03390266 0,03976344 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,03390266 0,03974318 ! methylation GO:0032259 64 43 0,000 0,03390266 0,03972293 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,03467824 0,04061097 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,03467824 0,0405903 ! glycolysis GO:0006096 53 44 0,000 0,03467824 0,04056966 ! regulation of action potential GO:0001508 71 44 0,000 0,03467824 0,04054903 ! regulation of ion transport GO:0043269 57 44 0,000 0,03467824 0,04052843 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,03467824 0,04050785 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,03467824 0,04048728 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,03467824 0,04046674 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,03467824 0,04044622 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,03467824 0,04042572 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,03467824 0,04040524 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,03467824 0,04038478 ! regulation of mast cell proliferation GO:0070666 64 44 0,000 0,03467824 0,04036435 ! RNA catabolic process GO:0006401 64 45 0,000 0,03545324 0,04124555 ! positive regulation of defense response GO:0031349 59 45 0,000 0,03545324 0,0412247 ! regulation of translational initiation GO:0006446 64 45 0,000 0,03545324 0,04120387 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,03545324 0,04118306 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,03545324 0,04116227 ! cell recognition GO:0008037 58 45 0,000 0,03545324 0,0411415 ! cell maturation GO:0048469 60 45 0,000 0,03545324 0,04112075 ! protein amino acid autophosphorylation GO:0046777 80 45 0,000 0,03545324 0,04110003 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,03622767 0,04197664 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,03622767 0,04195551 ! cell redox homeostasis GO:0045454 63 46 0,000 0,03622767 0,04193439 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,03622767 0,0419133 ! regulation of ossification GO:0030278 71 46 0,000 0,03622767 0,04189222 ! histone modification GO:0016570 68 46 0,000 0,03622767 0,04187117 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,03622767 0,04185014 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,03700151 0,04272263 ! viral infectious cycle GO:0019058 71 47 0,000 0,03700151 0,0427012 ! endocrine system development GO:0035270 83 47 0,000 0,03700151 0,04267978 ! covalent chromatin modification GO:0016569 75 47 0,000 0,03700151 0,04265839 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,03700151 0,04263702 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,03700151 0,04261567 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,03700151 0,04259434 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,03700151 0,04257303 ! regulation of leukocyte proliferation GO:0070663 71 47 0,000 0,03700151 0,04255174 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,03700151 0,04253048 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,03700151 0,04250923 ! chloride transport GO:0006821 67 48 0,000 0,03777479 0,04337594 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,03777479 0,04335429 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 0,000 0,03777479 0,04333267 ! response to temperature stimulus GO:0009266 62 48 0,000 0,03777479 0,04331107 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,03777479 0,04328949 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,03777479 0,04326793 ! gastrulation GO:0007369 73 48 0,000 0,03777479 0,04324639 ! heart morphogenesis GO:0003007 65 48 0,000 0,03777479 0,04322488 ! regulation of DNA replication GO:0006275 75 48 0,000 0,03777479 0,04320338 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,03777479 0,04318191 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,03777479 0,04316046 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,03777479 0,04313903 ! regulation of endocytosis GO:0030100 63 48 0,000 0,03777479 0,04311762 ! nuclear export GO:0051168 69 48 0,000 0,03777479 0,04309623 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,03777479 0,04307487 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,03777479 0,04305352 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,03854748 0,04391243 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,03854748 0,04389069 ! sensory perception of smell GO:0007608 61 49 0,000 0,03854748 0,04386898 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,03854748 0,04384728 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,03854748 0,04382561 ! RNA elongation GO:0006354 62 49 0,000 0,03854748 0,04380395 ! regulation of intracellular transport GO:0032386 78 49 0,000 0,03854748 0,04378232 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,03854748 0,04376071 ! germ cell development GO:0007281 68 49 0,000 0,03854748 0,04373912 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,03854748 0,04371756 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,03854748 0,04369601 ! cartilage development GO:0051216 70 49 0,000 0,03854748 0,04367448 ! maintenance of location GO:0051235 84 49 0,000 0,03854748 0,04365298 ! regulation of actin filament length GO:0030832 72 50 0,000 0,0393196 0,04450545 ! ear development GO:0043583 72 50 0,000 0,0393196 0,04448356 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,0393196 0,04446169 ! membrane fusion GO:0006944 80 50 0,000 0,0393196 0,04443984 ! lipid modification GO:0030258 73 50 0,000 0,0393196 0,04441801 ! positive regulation of growth GO:0045927 67 50 0,000 0,0393196 0,04439621 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,0393196 0,04437442 ! proton transport GO:0015992 75 50 0,000 0,0393196 0,04435266 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,0393196 0,04433092 ! positive regulation of secretion GO:0051047 71 51 0,000 0,04009114 0,04517865 ! hydrogen transport GO:0006818 77 51 0,000 0,04009114 0,04515652 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,04009114 0,04513442 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 0,000 0,04009114 0,04511234 ! positive regulation of cell migration GO:0030335 92 51 0,000 0,04009114 0,04509028 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,04009114 0,04506824 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,04009114 0,04504622 ! adult behavior GO:0030534 80 51 0,000 0,04009114 0,04502423 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,04009114 0,04500226 ! transition metal ion transport GO:0000041 74 52 0,000 0,04086211 0,04584529 ! regulation of cellular component size GO:0032535 74 52 0,000 0,04086211 0,04582294 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,04086211 0,04580061 ! aging GO:0007568 79 52 0,000 0,04086211 0,0457783 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,04086211 0,04575601 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,04086211 0,04573375 ! establishment of organelle localization GO:0051656 85 52 0,000 0,04086211 0,0457115 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,0416325 0,04655068 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,0416325 0,04652806 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,0416325 0,04650546 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,0416325 0,04648289 ! kidney development GO:0001822 90 53 0,000 0,0416325 0,04646033 ! single fertilization GO:0007338 59 53 0,000 0,0416325 0,0464378 ! cell projection assembly GO:0030031 76 53 0,000 0,0416325 0,04641529 ! amino acid transport GO:0006865 84 54 0,000 0,04240232 0,04725064 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,04240232 0,04722776 ! regulation of mitosis GO:0007088 84 54 0,000 0,04240232 0,0472049 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,04240232 0,04718206 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,04240232 0,04715925 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,04240232 0,04713646 ! DNA catabolic process GO:0006308 67 54 0,000 0,04240232 0,04711368 ! detection of external stimulus GO:0009581 66 54 0,000 0,04240232 0,04709094 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,04240232 0,04706821 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,04240232 0,0470455 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,04240232 0,04702282 ! exocytosis GO:0006887 74 55 0,000 0,04317156 0,04785281 ! mesoderm development GO:0007498 76 55 0,000 0,04317156 0,04782976 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,04317156 0,04780673 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,04317156 0,04778373 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,04394023 0,04861112 ! positive regulation of cell motion GO:0051272 99 56 0,000 0,04394023 0,04858775 ! negative regulation of protein kinase activity GO:0006469 99 57 0,000 0,04470832 0,04941333 ! carbohydrate transport GO:0008643 74 57 0,000 0,04470832 0,0493896 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,04470832 0,04936589 GO:0048609|reproductive process in a multicellular organism, ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,04470832 0,0493422 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,04470832 0,04931854 ! camera-type eye development GO:0043010 88 57 0,000 0,04470832 0,04929489 ! secondary metabolic process GO:0019748 84 57 0,000 0,04470832 0,04927127 ! response to peptide hormone stimulus GO:0043434 84 57 0,000 0,04470832 0,04924768 ! developmental maturation GO:0021700 75 57 0,000 0,04470832 0,0492241 ! gonad development GO:0008406 79 57 0,000 0,04470832 0,04920055 ! negative regulation of kinase activity GO:0033673 100 58 0,000 0,04547585 0,05002126 ! viral reproductive process GO:0022415 87 58 0,000 0,04547585 0,04999735 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,04547585 0,04997346 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,04547585 0,04994959 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,0462428 0,05076775 ! activation of MAPK activity GO:0000187 84 59 0,000 0,0462428 0,05074353 ! lung development GO:0030324 94 59 0,000 0,0462428 0,05071933 ! actin filament organization GO:0007015 95 59 0,000 0,0462428 0,05069515 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,0462428 0,050671 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,0462428 0,05064687 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,04700917 0,05146173 ! phosphoinositide metabolic process GO:0030384 87 60 0,000 0,04700917 0,05143725 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,04700917 0,05141279 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,04700917 0,05138836 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,04700917 0,05136394 ! regulation of heart contraction GO:0008016 91 60 0,000 0,04700917 0,05133955 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,04700917 0,05131519 ! fertilization GO:0009566 68 60 0,000 0,04700917 0,05129085 ! regulation of homeostatic process GO:0032844 105 60 0,000 0,04700917 0,05126653 ! meiosis GO:0007126 96 61 0,000 0,04777498 0,05207699 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 114 61 0,000 0,04777498 0,05205232 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,04777498 0,05202768 ! urogenital system development GO:0001655 101 61 0,000 0,04777498 0,05200306 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,04777498 0,05197846 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,04777498 0,05195388 ! extracellular matrix organization GO:0030198 103 61 0,000 0,04777498 0,05192933 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,04777498 0,0519048 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! negative regulation of transferase activity GO:0051348 105 61 0,000 0,04777498 0,05188029 ! amine catabolic process GO:0009310 90 62 0,000 0,04854022 0,05268641 ! neurotransmitter transport GO:0006836 81 62 0,000 0,04854022 0,05266155 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,04854022 0,05263673 ! negative regulation of cell growth GO:0030308 106 62 0,000 0,04854022 0,05261192 ! respiratory tube development GO:0030323 99 62 0,000 0,04854022 0,05258714 ! meiotic cell cycle GO:0051321 97 62 0,000 0,04854022 0,05256238 ! organelle localization GO:0051640 96 62 0,000 0,04854022 0,05253764 ! regulation of transcription factor activity GO:0051090 97 63 0,000 0,04930488 0,05334018 GO:0090046|regulation of transcription regulator activity, ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,04930488 0,0533151 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 0,000 0,04930488 0,05329005 ! viral reproduction GO:0016032 92 63 0,000 0,04930488 0,05326502 ! regulation of lipase activity GO:0060191 109 63 0,000 0,04930488 0,05324001 ! negative regulation of cell size GO:0045792 108 64 0,000 0,05006897 0,05403972 ! appendage morphogenesis GO:0035107 93 64 0,000 0,05006897 0,05401437 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,05006897 0,05398905 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,05006897 0,05396375 ! hexose catabolic process GO:0019320 82 64 0,000 0,05006897 0,05393847 ! respiratory system development GO:0060541 100 64 0,000 0,05006897 0,05391322 ! adaptive immune response GO:0002250 94 64 0,000 0,05006897 0,05388799 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 90 65 0,000 0,05083249 0,05468416 ! regulation of caspase activity GO:0043281 97 65 0,000 0,05083249 0,0546586 ! appendage development GO:0048736 94 65 0,000 0,05083249 0,05463305 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 0,000 0,05083249 0,05460754 ! defense response to bacterium GO:0042742 73 65 0,000 0,05083249 0,05458204 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,05083249 0,05455657 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,05083249 0,05453113 ! activation of immune response GO:0002253 83 65 0,000 0,05083249 0,0545057 ! protein oligomerization GO:0051259 100 65 0,000 0,05083249 0,05448031 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,05159545 0,05527225 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,05159545 0,05524652 ! antigen processing and presentation GO:0019882 96 66 0,000 0,05159545 0,05522081 ! axon guidance GO:0007411 99 66 0,000 0,05159545 0,05519513 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,05159545 0,05516947 ! regulation of immune effector process GO:0002697 101 66 0,000 0,05159545 0,05514383 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,05235783 0,05593266 ! regulation of endopeptidase activity GO:0052548 99 67 0,000 0,05235783 0,05590669 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,05235783 0,05588075 ! acute inflammatory response GO:0002526 92 68 0,000 0,05311964 0,05666752 ! learning or memory GO:0007611 123 68 0,000 0,05311964 0,05664125 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,05311964 0,056615 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,05311964 0,05658878 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,05311964 0,05656258 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,05311964 0,05653641 ! rhythmic process GO:0048511 105 68 0,000 0,05311964 0,05651026 ! inorganic anion transport GO:0015698 93 68 0,000 0,05311964 0,05648413 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,05388089 0,05726712 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,05388089 0,05724067 ! response to drug GO:0042493 108 69 0,000 0,05388089 0,05721424 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,05464157 0,0579952 ! humoral immune response GO:0006959 86 70 0,000 0,05464157 0,05796845 ! eye development GO:0001654 111 70 0,000 0,05464157 0,05794172 ! amine transport GO:0015837 101 70 0,000 0,05464157 0,05791502 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,05464157 0,05788835 ! regulation of catabolic process GO:0009894 106 70 0,000 0,05464157 0,05786169 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,05540167 0,0586396 ! muscle cell differentiation GO:0042692 104 71 0,000 0,05540167 0,05861263 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,05540167 0,05858568 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,05540167 0,05855876 ! regulation of peptidase activity GO:0052547 106 72 0,000 0,05616122 0,05933431 ! response to hypoxia GO:0001666 132 72 0,000 0,05616122 0,05930707 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,05616122 0,05927985 ! negative regulation of transport GO:0051051 116 73 0,000 0,05692019 0,06005341 ! regulation of blood pressure GO:0008217 107 73 0,000 0,05692019 0,06002588 ! tube morphogenesis GO:0035239 118 73 0,000 0,05692019 0,05999837 ! mitochondrion organization GO:0007005 104 73 0,000 0,05692019 0,05997088 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,05692019 0,05994342 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,0576786 0,06071431 ! response to oxygen levels GO:0070482 137 74 0,000 0,0576786 0,06068654 ! digestion GO:0007586 97 74 0,000 0,0576786 0,06065879 ! protein import into nucleus GO:0006606 118 74 0,000 0,0576786 0,06063107 ! cellular response to hormone stimulus GO:0032870 109 74 0,000 0,0576786 0,06060337 ! positive regulation of lymphocyte activation GO:0051251 108 74 0,000 0,0576786 0,0605757 ! blood coagulation GO:0007596 116 75 0,000 0,05843644 0,06134359 GO:0050817|coagulation, ! negative regulation of growth GO:0045926 123 75 0,000 0,05843644 0,06131561 ! response to nutrient GO:0007584 104 75 0,000 0,05843644 0,06128765 ! nuclear import GO:0051170 121 75 0,000 0,05843644 0,06125971 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,05843644 0,0612318 ! amine biosynthetic process GO:0009309 97 76 0,000 0,05919371 0,06199706 ! tRNA metabolic process GO:0006399 95 76 0,000 0,05919371 0,06196884 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,05919371 0,06194065 ! regulation of protein transport GO:0051223 114 76 0,000 0,05919371 0,06191248 GO:0070201|regulation of establishment of protein localization, ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,05995042 0,06267544 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,05995042 0,06264697 ! regulation of DNA binding GO:0051101 119 77 0,000 0,05995042 0,06261852 ! gland development GO:0048732 148 77 0,000 0,05995042 0,06259009 ! sex differentiation GO:0007548 105 77 0,000 0,05995042 0,0625617 ! protein ubiquitination GO:0016567 125 77 0,000 0,05995042 0,06253332 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,05995042 0,06250498 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,05995042 0,06247665 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,05995042 0,06244836 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,06070657 0,06320738 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,06070657 0,06317878 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,06146215 0,0639362 ! cellular respiration GO:0045333 107 79 0,000 0,06146215 0,0639073 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,06146215 0,06387842 ! T cell activation GO:0042110 134 79 0,000 0,06146215 0,06384957 ! regulation of lyase activity GO:0051339 133 79 0,000 0,06146215 0,06382074 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,06146215 0,06379194 ! chromatin assembly GO:0031497 102 80 0,000 0,06221716 0,06454645 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,06221716 0,06451735 ! protein localization in nucleus GO:0034504 133 80 0,000 0,06221716 0,06448827 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,06221716 0,06445922 ! forebrain development GO:0030900 131 80 0,000 0,06221716 0,0644302 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,06297161 0,06518214 ! hemostasis GO:0007599 125 81 0,000 0,06297161 0,06515282 ! mRNA transport GO:0051028 121 81 0,000 0,06297161 0,06512352 ! regulation of neurological system process GO:0031644 122 81 0,000 0,06297161 0,06509425 ! vitamin metabolic process GO:0006766 103 81 0,000 0,06297161 0,06506501 ! positive regulation of cell activation GO:0050867 120 81 0,000 0,06297161 0,06503579 GO:0002696|positive regulation of leukocyte activation, ! ossification GO:0001503 134 82 0,000 0,0637255 0,06578485 GO:0060348|bone development, ! detection of stimulus GO:0051606 108 82 0,000 0,0637255 0,06575534 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,06447883 0,06650283 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,06447883 0,06647302 ! regulation of cell adhesion GO:0030155 159 83 0,000 0,06447883 0,06644324 ! regulation of defense response GO:0031347 117 84 0,000 0,06523159 0,06718883 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,06523159 0,06715875 ! sterol metabolic process GO:0016125 120 84 0,000 0,06523159 0,0671287 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,06598379 0,06787241 ! rRNA metabolic process GO:0016072 107 85 0,000 0,06598379 0,06784207 GO:0006364|rRNA processing, ! positive regulation of MAP kinase activity GO:0043406 121 85 0,000 0,06598379 0,06781176 ! transcription initiation GO:0006352 118 85 0,000 0,06598379 0,06778147 ! anterior/posterior pattern formation GO:0009952 124 85 0,000 0,06598379 0,06775121 ! regulation of protein localization GO:0032880 132 85 0,000 0,06598379 0,06772098 ! regulation of membrane potential GO:0042391 128 85 0,000 0,06598379 0,06769077 ! negative regulation of multicellular organismal process GO:0051241 133 85 0,000 0,06598379 0,06766059 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,06673542 0,06840084 ! cell cycle arrest GO:0007050 150 86 0,000 0,06673542 0,06837037 ! nucleosome organization GO:0034728 114 87 0,000 0,0674865 0,06910906 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,0674865 0,0690783 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,0674865 0,06904757 ! skeletal muscle tissue development GO:0007519 123 87 0,000 0,0674865 0,06901687 GO:0060538|skeletal muscle organ development, ! female pregnancy GO:0007565 130 87 0,000 0,0674865 0,0689862 ! Wnt receptor signaling pathway GO:0016055 130 87 0,000 0,0674865 0,06895555 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,06823701 0,06969144 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,06823701 0,06966051 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,06823701 0,06962961 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,06823701 0,06959873 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 0,000 0,06823701 0,06956788 ! regulation of neurogenesis GO:0050767 153 89 0,000 0,06898697 0,07030129 ! reproductive developmental process GO:0003006 127 89 0,000 0,06898697 0,07027016 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,06898697 0,07023905 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,06898697 0,07020797 ! regulation of T cell activation GO:0050863 128 89 0,000 0,06898697 0,07017692 ! leukocyte differentiation GO:0002521 143 90 0,000 0,06973636 0,07090788 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,06973636 0,07087655 ! hormone metabolic process GO:0042445 121 90 0,000 0,06973636 0,07084524 ! RNA localization GO:0006403 135 91 0,000 0,07048519 0,07157437 ! ATP metabolic process GO:0046034 137 91 0,000 0,07048519 0,07154278 ! response to virus GO:0009615 122 91 0,000 0,07048519 0,07151122 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,07123346 0,07223852 ! glycerophospholipid metabolic process GO:0006650 130 92 0,000 0,07123346 0,07220668 ! cell fate commitment GO:0045165 141 92 0,000 0,07123346 0,07217487 ! positive regulation of immune response GO:0050778 121 92 0,000 0,07123346 0,07214309 ! sulfur metabolic process GO:0006790 118 92 0,000 0,07123346 0,07211134 ! peptidyl-amino acid modification GO:0018193 147 93 0,000 0,07198118 0,07283621 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,07198118 0,07280418 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,07198118 0,07277218 ! electron transport chain GO:0022900 123 94 0,000 0,07272833 0,07349524 ! response to oxidative stress GO:0006979 141 94 0,000 0,07272833 0,07346296 ! regulation of binding GO:0051098 151 95 0,000 0,07347493 0,07418452 ! angiogenesis GO:0001525 149 95 0,000 0,07347493 0,07415197 ! carboxylic acid transport GO:0046942 147 95 0,000 0,07347493 0,07411944 GO:0015849|organic acid transport, ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,07422096 0,0748392 ! in utero embryonic development GO:0001701 147 96 0,000 0,07422096 0,0748064 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,07422096 0,07477364 ! regulation of cellular component biogenesis GO:0044087 158 96 0,000 0,07422096 0,0747409 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,07422096 0,07470819 ! protein maturation GO:0051604 129 96 0,000 0,07422096 0,07467551 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,07496644 0,07539257 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,07496644 0,07535962 ! calcium ion transport GO:0006816 167 99 0,000 0,07645573 0,07682314 ! extracellular structure organization GO:0043062 156 99 0,000 0,07645573 0,0767896 ! protein import GO:0017038 156 99 0,000 0,07645573 0,07675608 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 0,000 0,07645573 0,07672259 ! regulation of translation GO:0006417 151 100 0,000 0,07719954 0,07743521 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,07719954 0,07740146 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,07719954 0,07736773 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,07719954 0,07733403 ! divalent metal ion transport GO:0070838 171 100 0,000 0,07719954 0,07730036 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,07719954 0,07726673 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,07719954 0,07723312 ! protein localization in organelle GO:0033365 161 100 0,000 0,07719954 0,07719954