pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-b2/out-0.05-06-0.01-300-run-b2//th1-pval-1e-01-06-th2-pval-1e-02-02-th3-pval-1e-01-01-run-b2/go_data/3178-4-real-Loi_GPL570-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! positive regulation of cell cycle GO:0045787 96 48 2,000 8,325E-07 2,034E-03 ! meiotic chromosome segregation GO:0045132 10 5 1,000 1,44E-06 1,759E-03 ! establishment of spindle localization GO:0051293 16 6 1,000 2,159E-06 1,758E-03 GO:0051653|spindle localization, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 4,028E-06 2,46E-03 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 1,000 1,723E-05 8,42E-03 ! negative regulation of cell cycle process GO:0010948 35 17 1,000 1,953E-05 7,951E-03 ! cellular response to unfolded protein GO:0034620 35 20 1,000 2,726E-05 9,514E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 1,000 3,313E-05 0,01011676 ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 4,657E-05 0,01264064 ! positive regulation of nuclear division GO:0051785 41 26 1,000 4,657E-05 0,01137658 GO:0045840|positive regulation of mitosis, ! regulation of chromosome organization GO:0033044 49 27 1,000 5,028E-05 0,01116722 ! fat cell differentiation GO:0045444 57 28 1,000 5,414E-05 0,01102157 ! base-excision repair GO:0006284 41 28 1,000 5,414E-05 0,01017375 ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 5,813E-05 0,01014456 ! spindle organization GO:0007051 50 32 1,000 7,097E-05 0,01155932 ! mitotic sister chromatid segregation GO:0000070 63 36 1,000 9,007E-05 0,01375218 ! sister chromatid segregation GO:0000819 65 37 1,000 9,519E-05 0,01367976 ! meiosis I GO:0007127 74 38 1,000 1,005E-04 0,01363447 ! cytokinesis GO:0000910 84 42 1,000 1,229E-04 0,01580571 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 1,000 1,476E-04 0,01803366 ! response to calcium ion GO:0051592 94 49 1,000 1,676E-04 0,01950151 ! response to UV GO:0009411 120 55 1,000 2,114E-04 0,02347457 ! regulation of DNA replication GO:0006275 105 56 1,000 2,192E-04 0,02328033 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 1,000 2,271E-04 0,02311639 ! nucleotide-excision repair GO:0006289 91 57 1,000 2,271E-04 0,02219174 ! positive regulation of organelle organization GO:0010638 108 58 1,000 2,352E-04 0,02209532 ! establishment of organelle localization GO:0051656 122 59 1,000 2,433E-04 0,02201858 ! regulation of mitosis GO:0007088 112 63 1,000 2,775E-04 0,02421343 GO:0051783|regulation of nuclear division, ! chromosome segregation GO:0007059 127 67 1,000 3,139E-04 0,02644308 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 1,000 3,233E-04 0,02633031 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 1,000 3,329E-04 0,02623567 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 1,000 3,625E-04 0,02767219 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 1,000 3,625E-04 0,02683364 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 1,000 3,829E-04 0,02750951 ! organelle localization GO:0051640 155 74 1,000 3,829E-04 0,02672353 ! phosphoinositide-mediated signaling GO:0048015 141 75 1,000 3,933E-04 0,02668701 ! positive regulation of ligase activity GO:0051351 130 77 1,000 4,145E-04 0,02736634 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 1,000 4,362E-04 0,02804508 ! negative regulation of organelle organization GO:0010639 181 80 1,000 4,473E-04 0,02802034 ! meiosis GO:0007126 143 81 1,000 4,585E-04 0,02800517 GO:0051327|M phase of meiotic cell cycle, ! positive regulation of phosphorylation GO:0042327 149 81 1,000 4,585E-04 0,02732212 ! meiotic cell cycle GO:0051321 144 82 1,000 4,699E-04 0,02733223 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 4,814E-04 0,02734962 GO:0045937|positive regulation of phosphate metabolic process, ! response to metal ion GO:0010038 158 84 1,000 4,93E-04 0,02737378 ! regulation of ligase activity GO:0051340 147 84 1,000 4,93E-04 0,02676548 ! response to inorganic substance GO:0010035 173 90 1,000 5,657E-04 0,03004129 ! positive regulation of protein modification process GO:0031401 156 90 1,000 5,657E-04 0,02940211 ! response to unfolded protein GO:0006986 139 90 1,000 5,657E-04 0,02878957 ! regulation of cell cycle process GO:0010564 161 90 1,000 5,657E-04 0,02820203 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 1,000 6,038E-04 0,02950201 GO:0010498|proteasomal protein catabolic process, ! response to protein stimulus GO:0051789 158 96 1,000 6,432E-04 0,03080934 ! regulation of DNA metabolic process GO:0051052 188 97 1,000 6,566E-04 0,03084605 ! interphase of mitotic cell cycle GO:0051329 224 98 1,000 6,701E-04 0,0308876 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 1,968E-03 0,08903151 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 1,968E-03 0,08741276 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 1,968E-03 0,08585181 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 1,968E-03 0,08434564 ! positive regulation of helicase activity GO:0051096 12 5 0,000 1,968E-03 0,08289141 ! neuron fate determination GO:0048664 7 5 0,000 1,968E-03 0,08148647 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 1,968E-03 0,08012836 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 1,968E-03 0,07881478 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 1,968E-03 0,07754357 ! polyol transport GO:0015791 12 5 0,000 1,968E-03 0,07631272 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 1,968E-03 0,07512034 ! response to superoxide GO:0000303 10 5 0,000 1,968E-03 0,07396464 ! negative regulation of bone resorption GO:0045779 10 5 0,000 1,968E-03 0,07284396 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 1,968E-03 0,07175674 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 1,968E-03 0,07070149 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 1,968E-03 0,06967684 ! female meiosis GO:0007143 10 5 0,000 1,968E-03 0,06868145 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 1,968E-03 0,06771411 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 1,968E-03 0,06677363 ! hypothalamus development GO:0021854 9 5 0,000 1,968E-03 0,06585893 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 1,968E-03 0,06496894 ! cobalt ion transport GO:0006824 11 5 0,000 1,968E-03 0,06410269 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 1,968E-03 0,06325923 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 1,968E-03 0,06243768 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 1,968E-03 0,0616372 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 1,968E-03 0,06085698 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 1,968E-03 0,06009627 ! embryonic camera-type eye development GO:0031076 12 5 0,000 1,968E-03 0,05935434 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 1,968E-03 0,05863051 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 1,968E-03 0,05792412 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 1,968E-03 0,05723454 ! transposition GO:0032196 9 5 0,000 1,968E-03 0,0565612 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 1,968E-03 0,05590351 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 1,968E-03 0,05526094 ! negative chemotaxis GO:0050919 16 5 0,000 1,968E-03 0,05463297 ! positive regulation of histone modification GO:0031058 6 5 0,000 1,968E-03 0,05401912 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 1,968E-03 0,05341891 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 1,968E-03 0,05283189 ! behavioral response to pain GO:0048266 10 5 0,000 1,968E-03 0,05225763 ! clathrin coat assembly GO:0048268 15 5 0,000 1,968E-03 0,05169572 ! Notch receptor processing GO:0007220 11 5 0,000 1,968E-03 0,05114576 ! regulation of dopamine uptake GO:0051584 9 5 0,000 1,968E-03 0,05060739 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 1,968E-03 0,05008023 ! micturition GO:0060073 9 5 0,000 1,968E-03 0,04956393 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 1,968E-03 0,04905818 ! copulation GO:0007620 9 5 0,000 1,968E-03 0,04856264 ! glial cell fate commitment GO:0021781 14 5 0,000 1,968E-03 0,04807702 ! protein maturation by protein folding GO:0022417 14 5 0,000 1,968E-03 0,04760101 ! bioluminescence GO:0008218 9 5 0,000 1,968E-03 0,04713433 ! spermidine metabolic process GO:0008216 7 5 0,000 1,968E-03 0,04667671 ! regulation of potassium ion transport GO:0043266 10 5 0,000 1,968E-03 0,0462279 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 1,968E-03 0,04578763 ! apoptotic cell clearance GO:0043277 23 5 0,000 1,968E-03 0,04535568 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 1,968E-03 0,04493179 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 1,968E-03 0,04451576 ! lipoprotein particle clearance GO:0034381 10 5 0,000 1,968E-03 0,04410735 ! grooming behavior GO:0007625 6 5 0,000 1,968E-03 0,04370638 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 1,968E-03 0,04331263 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 1,968E-03 0,04292591 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 1,968E-03 0,04254603 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 1,968E-03 0,04217282 ! response to protozoan GO:0001562 13 5 0,000 1,968E-03 0,0418061 ! positive regulation of glycolysis GO:0045821 13 5 0,000 1,968E-03 0,0414457 ! lymph vessel development GO:0001945 10 5 0,000 1,968E-03 0,04109147 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 1,968E-03 0,04074323 ! endochondral ossification GO:0001958 17 5 0,000 1,968E-03 0,04040085 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 1,968E-03 0,04006418 ! single strand break repair GO:0000012 8 5 0,000 1,968E-03 0,03973307 ! parathyroid gland development GO:0060017 14 5 0,000 1,968E-03 0,03940739 ! anagen GO:0042640 7 5 0,000 1,968E-03 0,03908701 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 1,968E-03 0,03877179 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 1,968E-03 0,03846161 ! cytokine secretion GO:0050663 15 5 0,000 1,968E-03 0,03815636 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 1,968E-03 0,03785592 ! ceramide catabolic process GO:0046514 7 5 0,000 1,968E-03 0,03756017 ! skeletal myofibril assembly GO:0014866 12 5 0,000 1,968E-03 0,037269 ! smooth muscle tissue development GO:0048745 32 5 0,000 1,968E-03 0,03698232 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 1,968E-03 0,03670001 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 1,968E-03 0,03642198 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 1,968E-03 0,03614813 ! cardiac muscle fiber development GO:0048739 12 5 0,000 1,968E-03 0,03587837 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 1,968E-03 0,0356126 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 1,968E-03 0,03535075 ! neutrophil mediated immunity GO:0002446 7 5 0,000 1,968E-03 0,03509271 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 1,968E-03 0,03483842 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 1,968E-03 0,03458778 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 1,968E-03 0,03434073 ! glycine biosynthetic process GO:0006545 7 5 0,000 1,968E-03 0,03409717 ! microvillus organization GO:0032528 8 5 0,000 1,968E-03 0,03385705 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 1,968E-03 0,03362029 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 1,968E-03 0,03338682 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 1,968E-03 0,03315656 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 1,968E-03 0,03292946 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 1,968E-03 0,03270545 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 1,968E-03 0,03248447 ! polyol catabolic process GO:0046174 9 5 0,000 1,968E-03 0,03226645 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 1,968E-03 0,03205134 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 1,968E-03 0,03183908 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 1,968E-03 0,03162962 ! muscle cell migration GO:0014812 8 5 0,000 1,968E-03 0,03142289 ! mitochondrial fission GO:0000266 8 5 0,000 1,968E-03 0,03121884 ! sister chromatid cohesion GO:0007062 15 5 0,000 1,968E-03 0,03101743 ! response to tumor necrosis factor GO:0034612 10 5 0,000 1,968E-03 0,0308186 ! mRNA transcription GO:0009299 10 5 0,000 1,968E-03 0,0306223 ! nerve growth factor processing GO:0032455 9 5 0,000 1,968E-03 0,03042849 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 1,968E-03 0,03023712 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 1,968E-03 0,03004814 ! anaerobic glycolysis GO:0019642 6 5 0,000 1,968E-03 0,0298615 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 1,968E-03 0,02967717 ! monocyte activation GO:0042117 10 5 0,000 1,968E-03 0,0294951 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 1,968E-03 0,02931525 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 1,968E-03 0,02913759 ! response to food GO:0032094 6 5 0,000 1,968E-03 0,02896206 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 1,968E-03 0,02878863 ! positive regulation of transporter activity GO:0032411 8 5 0,000 1,968E-03 0,02861727 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 1,968E-03 0,02844794 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 1,968E-03 0,0282806 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 1,968E-03 0,02811521 ! forebrain neuron development GO:0021884 13 5 0,000 1,968E-03 0,02795175 ! lipoprotein catabolic process GO:0042159 11 5 0,000 1,968E-03 0,02779018 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 1,968E-03 0,02763047 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 1,968E-03 0,02747258 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 1,968E-03 0,02731649 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 1,968E-03 0,02716216 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 1,968E-03 0,02700956 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 1,968E-03 0,02685867 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 1,968E-03 0,02670945 ! lipid glycosylation GO:0030259 7 5 0,000 1,968E-03 0,02656189 ! nucleobase transport GO:0015851 6 5 0,000 1,968E-03 0,02641594 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 1,968E-03 0,02627159 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 1,968E-03 0,02612881 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 1,968E-03 0,02598758 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 1,968E-03 0,02584786 ! basic amino acid transport GO:0015802 12 5 0,000 1,968E-03 0,02570963 ! cellular glucose homeostasis GO:0001678 6 5 0,000 1,968E-03 0,02557288 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 1,968E-03 0,02543757 ! actin nucleation GO:0045010 11 5 0,000 1,968E-03 0,02530369 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 1,968E-03 0,02517121 ! depurination GO:0045007 5 5 0,000 1,968E-03 0,02504011 ! depyrimidination GO:0045008 10 5 0,000 1,968E-03 0,02491037 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 1,968E-03 0,02478197 ! regulation of centrosome cycle GO:0046605 7 5 0,000 1,968E-03 0,02465488 ! G2/M transition checkpoint GO:0031576 8 5 0,000 1,968E-03 0,02452909 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 1,968E-03 0,02440458 ! zinc ion homeostasis GO:0055069 9 5 0,000 1,968E-03 0,02428132 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 1,968E-03 0,0241593 ! forebrain morphogenesis GO:0048853 13 5 0,000 1,968E-03 0,02403851 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 1,968E-03 0,02391891 ! activated T cell proliferation GO:0050798 16 5 0,000 1,968E-03 0,0238005 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 1,968E-03 0,02368326 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 1,968E-03 0,02356716 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 1,968E-03 0,0234522 ! positive regulation of organ growth GO:0046622 6 5 0,000 1,968E-03 0,02333836 ! gamma-delta T cell activation GO:0046629 6 5 0,000 1,968E-03 0,02322561 ! response to arsenic GO:0046685 11 5 0,000 1,968E-03 0,02311395 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 1,968E-03 0,02300336 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 1,968E-03 0,02289382 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 1,968E-03 0,02278532 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 1,968E-03 0,02267784 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 1,968E-03 0,02257137 ! response to mercury ion GO:0046689 8 5 0,000 1,968E-03 0,0224659 ! response to cadmium ion GO:0046686 7 5 0,000 1,968E-03 0,0223614 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 1,968E-03 0,02225788 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 1,968E-03 0,02215531 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 1,968E-03 0,02205368 ! bile acid biosynthetic process GO:0006699 7 5 0,000 1,968E-03 0,02195298 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 1,968E-03 0,02185319 ! ganglioside catabolic process GO:0006689 12 5 0,000 1,968E-03 0,02175431 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 1,968E-03 0,02165631 ! decidualization GO:0046697 11 5 0,000 1,968E-03 0,0215592 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 1,968E-03 0,02146295 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 1,968E-03 0,02136756 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 1,968E-03 0,02127302 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 1,968E-03 0,0211793 ! embryonic cleavage GO:0040016 6 5 0,000 1,968E-03 0,02108641 ! peroxisome fission GO:0016559 5 5 0,000 1,968E-03 0,02099433 ! histone demethylation GO:0016577 13 5 0,000 1,968E-03 0,02090305 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 1,968E-03 0,02081256 ! mitotic recombination GO:0006312 9 5 0,000 1,968E-03 0,02072285 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 1,968E-03 0,02063391 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 1,968E-03 0,02054573 ! metaphase plate congression GO:0051310 7 5 0,000 1,968E-03 0,0204583 ! regulation of sterol transport GO:0032371 7 5 0,000 1,968E-03 0,02037162 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 1,968E-03 0,02028566 ! enteric nervous system development GO:0048484 8 5 0,000 1,968E-03 0,02020043 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 1,968E-03 0,02011591 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 1,968E-03 0,02003209 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 1,968E-03 0,01994897 ! muscle cell proliferation GO:0033002 12 5 0,000 1,968E-03 0,01986654 ! skeletal muscle regeneration GO:0043403 8 5 0,000 1,968E-03 0,01978478 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 1,968E-03 0,0197037 ! B cell homeostasis GO:0001782 13 5 0,000 1,968E-03 0,01962327 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 1,968E-03 0,0195435 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 1,968E-03 0,01946438 ! metaphase GO:0051323 11 5 0,000 1,968E-03 0,01938589 ! melatonin biosynthetic process GO:0030187 7 5 0,000 1,968E-03 0,01930804 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 1,968E-03 0,01923081 ! cellular response to nutrient GO:0031670 8 5 0,000 1,968E-03 0,01915419 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 1,968E-03 0,01907818 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 1,968E-03 0,01900277 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 1,968E-03 0,01892796 ! regulation of hair follicle development GO:0051797 10 5 0,000 1,968E-03 0,01885373 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 1,968E-03 0,01878008 ! response to redox state GO:0051775 6 5 0,000 1,968E-03 0,01870701 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 1,968E-03 0,0186345 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 1,968E-03 0,01856255 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 1,968E-03 0,01849116 ! brown fat cell differentiation GO:0050873 7 5 0,000 1,968E-03 0,01842031 ! regulation of telomerase activity GO:0051972 7 5 0,000 1,968E-03 0,01835001 ! galactolipid metabolic process GO:0019374 7 5 0,000 1,968E-03 0,01828023 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 1,968E-03 0,01821099 ! porphyrin catabolic process GO:0006787 12 5 0,000 1,968E-03 0,01814227 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 1,968E-03 0,01807407 ! striatum development GO:0021756 14 5 0,000 1,968E-03 0,01800637 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 1,968E-03 0,01793919 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 1,968E-03 0,0178725 ! glial cell migration GO:0008347 10 5 0,000 1,968E-03 0,0178063 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 1,968E-03 0,0177406 ! neural plate morphogenesis GO:0001839 7 5 0,000 1,968E-03 0,01767537 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 1,968E-03 0,01761063 ! somatic stem cell maintenance GO:0035019 15 5 0,000 1,968E-03 0,01754636 ! T cell activation during immune response GO:0002286 9 5 0,000 1,968E-03 0,01748255 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 1,968E-03 0,01741921 ! negative regulation of lipase activity GO:0060192 8 5 0,000 1,968E-03 0,01735632 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 1,968E-03 0,01729389 ! neuroprotection GO:0043526 8 5 0,000 1,968E-03 0,01723191 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 1,968E-03 0,01717036 ! regulation of sensory perception GO:0051931 8 5 0,000 1,968E-03 0,01710926 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 1,968E-03 0,01704859 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 1,968E-03 0,01698835 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 1,968E-03 0,01692853 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 1,968E-03 0,01686913 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 1,968E-03 0,01681015 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 1,968E-03 0,01675157 ! sequestering of calcium ion GO:0051208 7 5 0,000 1,968E-03 0,01669341 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 1,968E-03 0,01663565 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 1,968E-03 0,01657828 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 1,968E-03 0,01652131 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 1,968E-03 0,01646473 ! spindle assembly GO:0051225 6 5 0,000 1,968E-03 0,01640854 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 1,968E-03 0,01635273 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 1,968E-03 0,01629729 ! protein palmitoylation GO:0018345 12 5 0,000 1,968E-03 0,01624224 ! drug metabolic process GO:0017144 7 5 0,000 1,968E-03 0,01618755 ! stem cell division GO:0017145 11 5 0,000 1,968E-03 0,01613323 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 1,968E-03 0,01607927 ! organ regeneration GO:0031100 7 5 0,000 1,968E-03 0,01602567 ! carnitine metabolic process GO:0009437 8 5 0,000 1,968E-03 0,01597243 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 1,968E-03 0,01591954 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 2,361E-03 0,01903692 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 2,361E-03 0,0189743 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 2,361E-03 0,01891209 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 2,361E-03 0,01885028 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 2,361E-03 0,01878888 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 2,361E-03 0,01872788 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 2,361E-03 0,01866727 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 2,361E-03 0,01860706 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 2,361E-03 0,01854723 ! response to oxygen radical GO:0000305 11 6 0,000 2,361E-03 0,01848778 ! positive regulation of axon extension GO:0045773 13 6 0,000 2,361E-03 0,01842871 ! myoblast cell fate commitment GO:0048625 18 6 0,000 2,361E-03 0,01837002 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 2,361E-03 0,01831171 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 2,361E-03 0,01825376 ! regulation of interferon-beta production GO:0032648 8 6 0,000 2,361E-03 0,01819617 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 2,361E-03 0,01813895 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 2,361E-03 0,01808209 ! forebrain regionalization GO:0021871 9 6 0,000 2,361E-03 0,01802558 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 2,361E-03 0,01796943 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 2,361E-03 0,01791362 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 2,361E-03 0,01785816 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 2,361E-03 0,01780305 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 2,361E-03 0,01774827 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 2,361E-03 0,01769383 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 2,361E-03 0,01763972 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 2,361E-03 0,01758594 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 2,361E-03 0,01753248 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 2,361E-03 0,01747935 ! malate metabolic process GO:0006108 13 6 0,000 2,361E-03 0,01742655 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 2,361E-03 0,01737406 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 2,361E-03 0,01732188 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 2,361E-03 0,01727002 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 2,361E-03 0,01721847 ! protein refolding GO:0042026 15 6 0,000 2,361E-03 0,01716722 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 2,361E-03 0,01711628 ! opsonization GO:0008228 8 6 0,000 2,361E-03 0,01706564 ! mating behavior GO:0007617 7 6 0,000 2,361E-03 0,0170153 ! erythrocyte maturation GO:0043249 8 6 0,000 2,361E-03 0,01696526 ! embryonic hemopoiesis GO:0035162 16 6 0,000 2,361E-03 0,0169155 ! protein amino acid dealkylation GO:0008214 15 6 0,000 2,361E-03 0,01686604 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 2,361E-03 0,01681687 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 2,361E-03 0,01676799 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 2,361E-03 0,01671938 ! response to interferon-gamma GO:0034341 16 6 0,000 2,361E-03 0,01667106 ! toxin metabolic process GO:0009404 11 6 0,000 2,361E-03 0,01662302 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 2,361E-03 0,01657525 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 2,361E-03 0,01652776 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 2,361E-03 0,01648053 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 2,361E-03 0,01643358 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 2,361E-03 0,0163869 ! cGMP-mediated signaling GO:0019934 14 6 0,000 2,361E-03 0,01634047 ! dorsal spinal cord development GO:0021516 10 6 0,000 2,361E-03 0,01629431 ! activation of MAPKKK activity GO:0000185 12 6 0,000 2,361E-03 0,01624841 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 2,361E-03 0,01620277 ! thymic T cell selection GO:0045061 16 6 0,000 2,361E-03 0,01615739 ! sphingoid catabolic process GO:0046521 8 6 0,000 2,361E-03 0,01611225 ! protein lipoylation GO:0009249 10 6 0,000 2,361E-03 0,01606737 ! transepithelial chloride transport GO:0030321 12 6 0,000 2,361E-03 0,01602274 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 2,361E-03 0,01597836 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 2,361E-03 0,01593422 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 2,361E-03 0,01589032 ! glutamate catabolic process GO:0006538 12 6 0,000 2,361E-03 0,01584667 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 2,361E-03 0,01580325 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 2,361E-03 0,01576007 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 2,361E-03 0,01571713 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 2,361E-03 0,01567442 ! hyperosmotic response GO:0006972 10 6 0,000 2,361E-03 0,01563194 ! L-serine biosynthetic process GO:0006564 7 6 0,000 2,361E-03 0,01558969 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 2,361E-03 0,01554767 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 2,361E-03 0,01550588 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 2,361E-03 0,01546431 ! urea metabolic process GO:0019627 7 6 0,000 2,361E-03 0,01542296 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 2,361E-03 0,01538183 ! neutrophil activation GO:0042119 7 6 0,000 2,361E-03 0,01534092 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 2,361E-03 0,01530023 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 2,361E-03 0,01525975 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 2,361E-03 0,01521949 ! paraxial mesoderm development GO:0048339 16 6 0,000 2,361E-03 0,01517944 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 2,361E-03 0,0151396 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 2,361E-03 0,01509997 ! neuron apoptosis GO:0051402 15 6 0,000 2,361E-03 0,01506054 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 2,361E-03 0,01502132 ! T cell mediated immunity GO:0002456 17 6 0,000 2,361E-03 0,0149823 ! negative regulation of platelet activation GO:0010544 9 6 0,000 2,361E-03 0,01494349 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 2,361E-03 0,01490488 ! carnitine transport GO:0015879 10 6 0,000 2,361E-03 0,01486646 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 2,361E-03 0,01482824 ! positive regulation of exocytosis GO:0045921 11 6 0,000 2,361E-03 0,01479022 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 2,361E-03 0,0147524 ! early endosome to late endosome transport GO:0045022 16 6 0,000 2,361E-03 0,01471476 ! 5S class rRNA transcription GO:0042791 13 6 0,000 2,361E-03 0,01467732 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 2,361E-03 0,01464007 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 2,361E-03 0,01460301 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 2,361E-03 0,01456613 ! sodium ion homeostasis GO:0055078 12 6 0,000 2,361E-03 0,01452944 ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 2,361E-03 0,01449293 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 2,361E-03 0,01445661 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 2,361E-03 0,01442047 ! response to UV-C GO:0010225 14 6 0,000 2,361E-03 0,01438451 ! astrocyte development GO:0014002 16 6 0,000 2,361E-03 0,01434872 ! protein targeting to lysosome GO:0006622 12 6 0,000 2,361E-03 0,01431312 ! purine base biosynthetic process GO:0009113 17 6 0,000 2,361E-03 0,01427769 ! interaction with symbiont GO:0051702 14 6 0,000 2,361E-03 0,01424244 ! regulation of dendrite development GO:0050773 16 6 0,000 2,361E-03 0,01420736 ! peptidyl-arginine modification GO:0018195 13 6 0,000 2,361E-03 0,01417245 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 2,361E-03 0,01413771 ! response to copper ion GO:0046688 10 6 0,000 2,361E-03 0,01410315 ! response to exogenous dsRNA GO:0043330 13 6 0,000 2,361E-03 0,01406875 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 2,361E-03 0,01403452 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 2,361E-03 0,01400045 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 2,361E-03 0,01396655 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 2,361E-03 0,01393282 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 2,361E-03 0,01389925 ! regulation of dopamine secretion GO:0014059 14 6 0,000 2,361E-03 0,01386583 ! nucleoside catabolic process GO:0009164 10 6 0,000 2,361E-03 0,01383258 ! hair follicle maturation GO:0048820 8 6 0,000 2,361E-03 0,01379949 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 2,361E-03 0,01376656 ! Schwann cell development GO:0014044 15 6 0,000 2,361E-03 0,01373378 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 2,361E-03 0,01370116 ! response to pheromone GO:0019236 6 6 0,000 2,361E-03 0,01366869 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 2,361E-03 0,01363638 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 2,361E-03 0,01360421 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 2,361E-03 0,0135722 ! base conversion or substitution editing GO:0016553 6 6 0,000 2,361E-03 0,01354035 ! subpallium development GO:0021544 15 6 0,000 2,361E-03 0,01350863 ! neural tube patterning GO:0021532 8 6 0,000 2,361E-03 0,01347707 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 2,361E-03 0,01344566 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 2,361E-03 0,01341439 ! maintenance of organ identity GO:0048496 9 6 0,000 2,361E-03 0,01338326 ! G2 phase GO:0051319 16 6 0,000 2,361E-03 0,01335228 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 2,361E-03 0,01332145 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 2,361E-03 0,01329075 ! oxygen homeostasis GO:0032364 10 6 0,000 2,361E-03 0,0132602 ! establishment of planar polarity GO:0001736 7 6 0,000 2,361E-03 0,01322979 ! regulation of mast cell activation GO:0033003 13 6 0,000 2,361E-03 0,01319951 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 2,361E-03 0,01316938 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 2,361E-03 0,01313938 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 2,361E-03 0,01310952 ! receptor internalization GO:0031623 11 6 0,000 2,361E-03 0,01307979 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 2,361E-03 0,0130502 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 2,361E-03 0,01302074 ! neutrophil homeostasis GO:0001780 11 6 0,000 2,361E-03 0,01299141 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 2,361E-03 0,01296222 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 2,361E-03 0,01293315 ! protein deubiquitination GO:0016579 16 6 0,000 2,361E-03 0,01290422 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 2,361E-03 0,01287542 ! protein destabilization GO:0031648 9 6 0,000 2,361E-03 0,01284674 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 2,361E-03 0,01281819 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 2,361E-03 0,01278977 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 2,361E-03 0,01276148 ! regulation of viral transcription GO:0046782 11 6 0,000 2,361E-03 0,0127333 ! progesterone metabolic process GO:0042448 12 6 0,000 2,361E-03 0,01270526 ! negative regulation of axon extension GO:0030517 24 6 0,000 2,361E-03 0,01267733 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 2,361E-03 0,01264953 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 2,361E-03 0,01262185 ! triglyceride catabolic process GO:0019433 10 6 0,000 2,361E-03 0,01259429 ! determination of adult lifespan GO:0008340 17 6 0,000 2,361E-03 0,01256686 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 2,361E-03 0,01253954 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 2,361E-03 0,01251234 ! neural plate development GO:0001840 9 6 0,000 2,361E-03 0,01248525 ! catecholamine transport GO:0051937 9 6 0,000 2,361E-03 0,01245829 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 2,361E-03 0,01243144 ! sensory cilium assembly GO:0035058 10 6 0,000 2,361E-03 0,0124047 ! organ or tissue specific immune response GO:0002251 8 6 0,000 2,361E-03 0,01237808 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 2,361E-03 0,01235158 ! maternal placenta development GO:0001893 12 6 0,000 2,361E-03 0,01232519 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 2,361E-03 0,01229891 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 2,361E-03 0,01227274 ! negative regulation of B cell activation GO:0050869 14 6 0,000 2,361E-03 0,01224668 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 2,361E-03 0,01222074 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 2,361E-03 0,0121949 ! positive regulation of coagulation GO:0050820 13 6 0,000 2,361E-03 0,01216917 ! cellular anion homeostasis GO:0030002 11 6 0,000 2,361E-03 0,01214355 GO:0055081|anion homeostasis, ! tRNA transcription GO:0009304 17 7 0,000 2,754E-03 0,01413513 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 2,754E-03 0,0141055 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 2,754E-03 0,01407599 ! behavioral response to cocaine GO:0048148 14 7 0,000 2,754E-03 0,0140466 ! regulation of helicase activity GO:0051095 16 7 0,000 2,754E-03 0,01401734 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 2,754E-03 0,01398819 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 2,754E-03 0,01395917 ! sleep GO:0030431 16 7 0,000 2,754E-03 0,01393027 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 2,754E-03 0,01390149 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 2,754E-03 0,01387283 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 2,754E-03 0,01384428 ! prostate gland development GO:0030850 14 7 0,000 2,754E-03 0,01381585 ! nucleotide-sugar transport GO:0015780 11 7 0,000 2,754E-03 0,01378754 ! synaptonemal complex assembly GO:0007130 10 7 0,000 2,754E-03 0,01375935 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 2,754E-03 0,01373127 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 2,754E-03 0,0137033 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 2,754E-03 0,01367545 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 2,754E-03 0,01364771 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 2,754E-03 0,01362008 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 2,754E-03 0,01359257 ! SMAD protein complex assembly GO:0007183 13 7 0,000 2,754E-03 0,01356516 ! glycolipid transport GO:0046836 11 7 0,000 2,754E-03 0,01353787 ! protein amino acid sulfation GO:0006477 10 7 0,000 2,754E-03 0,01351069 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 2,754E-03 0,01348361 ! neuron adhesion GO:0007158 14 7 0,000 2,754E-03 0,01345664 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 2,754E-03 0,01342978 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 2,754E-03 0,01340303 ! establishment of tissue polarity GO:0007164 8 7 0,000 2,754E-03 0,01337638 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 2,754E-03 0,01334984 ! mRNA stabilization GO:0048255 18 7 0,000 2,754E-03 0,01332341 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 2,754E-03 0,01329708 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 2,754E-03 0,01327085 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 2,754E-03 0,01324473 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 2,754E-03 0,01321871 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 2,754E-03 0,01319279 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 2,754E-03 0,01316697 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 2,754E-03 0,01314125 ! lipoprotein transport GO:0042953 14 7 0,000 2,754E-03 0,01311564 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 2,754E-03 0,01309012 ! rhythmic behavior GO:0007622 17 7 0,000 2,754E-03 0,0130647 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 2,754E-03 0,01303938 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 2,754E-03 0,01301416 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 2,754E-03 0,01298904 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 2,754E-03 0,01296401 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 2,754E-03 0,01293908 ! regulation of odontogenesis GO:0042481 14 7 0,000 2,754E-03 0,01291424 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 2,754E-03 0,0128895 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 2,754E-03 0,01286486 ! mechanosensory behavior GO:0007638 16 7 0,000 2,754E-03 0,01284031 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 2,754E-03 0,01281585 ! positive regulation of isotype switching GO:0045830 17 7 0,000 2,754E-03 0,01279149 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 2,754E-03 0,01276721 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 2,754E-03 0,01274303 ! protein-cofactor linkage GO:0018065 13 7 0,000 2,754E-03 0,01271894 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 2,754E-03 0,01269495 ! spinal cord patterning GO:0021511 14 7 0,000 2,754E-03 0,01267104 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 2,754E-03 0,01264722 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 2,754E-03 0,01262349 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 2,754E-03 0,01259985 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 2,754E-03 0,0125763 ! adrenal gland development GO:0030325 17 7 0,000 2,754E-03 0,01255284 ! cysteine metabolic process GO:0006534 13 7 0,000 2,754E-03 0,01252946 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 2,754E-03 0,01250617 ! ovulation GO:0030728 10 7 0,000 2,754E-03 0,01248297 ! adenohypophysis development GO:0021984 11 7 0,000 2,754E-03 0,01245985 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 2,754E-03 0,01243682 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 2,754E-03 0,01241388 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 2,754E-03 0,01239102 ! microtubule nucleation GO:0007020 21 7 0,000 2,754E-03 0,01236824 ! proline biosynthetic process GO:0006561 10 7 0,000 2,754E-03 0,01234554 ! tryptophan metabolic process GO:0006568 11 7 0,000 2,754E-03 0,01232293 ! thyroid hormone generation GO:0006590 13 7 0,000 2,754E-03 0,0123004 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 2,754E-03 0,01227796 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 2,754E-03 0,01225559 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 2,754E-03 0,01223331 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 2,754E-03 0,01221111 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 2,754E-03 0,01218899 ! galactose metabolic process GO:0006012 13 7 0,000 2,754E-03 0,01216695 ! vesicle fusion GO:0006906 20 7 0,000 2,754E-03 0,01214498 ! response to dietary excess GO:0002021 8 7 0,000 2,754E-03 0,0121231 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 2,754E-03 0,0121013 ! intracellular pH reduction GO:0051452 13 7 0,000 2,754E-03 0,01207957 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 2,754E-03 0,01205792 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 2,754E-03 0,01203635 ! organ growth GO:0035265 15 7 0,000 2,754E-03 0,01201486 ! nucleoside transport GO:0015858 11 7 0,000 2,754E-03 0,01199344 ! nucleoside salvage GO:0043174 11 7 0,000 2,754E-03 0,0119721 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 2,754E-03 0,01195084 ! male sex determination GO:0030238 15 7 0,000 2,754E-03 0,01192965 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 2,754E-03 0,01190853 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 2,754E-03 0,01188749 ! parturition GO:0007567 16 7 0,000 2,754E-03 0,01186653 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 2,754E-03 0,01184564 ! rRNA modification GO:0000154 14 7 0,000 2,754E-03 0,01182482 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 2,754E-03 0,01180407 ! spindle checkpoint GO:0031577 16 7 0,000 2,754E-03 0,0117834 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 2,754E-03 0,0117628 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 2,754E-03 0,01174227 ! monocyte differentiation GO:0030224 16 7 0,000 2,754E-03 0,01172181 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 2,754E-03 0,01170143 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 2,754E-03 0,01168111 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 2,754E-03 0,01166087 ! hyaluronan metabolic process GO:0030212 9 7 0,000 2,754E-03 0,01164069 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 2,754E-03 0,01162059 ! anterograde axon cargo transport GO:0008089 18 7 0,000 2,754E-03 0,01160055 ! fibrinolysis GO:0042730 11 7 0,000 2,754E-03 0,01158059 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 2,754E-03 0,01156069 ! skeletal muscle contraction GO:0003009 8 7 0,000 2,754E-03 0,01154086 ! eating behavior GO:0042755 8 7 0,000 2,754E-03 0,0115211 ! B cell lineage commitment GO:0002326 21 7 0,000 2,754E-03 0,0115014 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 2,754E-03 0,01148178 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 2,754E-03 0,01146222 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 2,754E-03 0,01144272 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 2,754E-03 0,0114233 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 2,754E-03 0,01140393 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 2,754E-03 0,01138464 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 2,754E-03 0,01136541 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 2,754E-03 0,01134624 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 2,754E-03 0,01132714 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 2,754E-03 0,0113081 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 2,754E-03 0,01128913 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 2,754E-03 0,01127022 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 2,754E-03 0,01125137 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 2,754E-03 0,01123259 ! histone ubiquitination GO:0016574 9 7 0,000 2,754E-03 0,01121387 ! regulation of meiosis GO:0040020 12 7 0,000 2,754E-03 0,01119521 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 2,754E-03 0,01117661 ! T cell lineage commitment GO:0002360 16 7 0,000 2,754E-03 0,01115808 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 2,754E-03 0,0111396 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 2,754E-03 0,01112119 ! membrane to membrane docking GO:0022614 14 7 0,000 2,754E-03 0,01110284 ! transcription termination GO:0006353 14 7 0,000 2,754E-03 0,01108455 ! coenzyme A metabolic process GO:0015936 12 7 0,000 2,754E-03 0,01106632 ! anaphase GO:0051322 18 7 0,000 2,754E-03 0,01104815 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 2,754E-03 0,01103003 ! axonal fasciculation GO:0007413 19 7 0,000 2,754E-03 0,01101198 ! negative regulation of nuclear division GO:0051784 15 7 0,000 2,754E-03 0,01099399 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 2,754E-03 0,01097605 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 2,754E-03 0,01095818 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 2,754E-03 0,01094036 ! diuresis GO:0030146 12 7 0,000 2,754E-03 0,0109226 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 2,754E-03 0,0109049 ! thiamin metabolic process GO:0006772 7 7 0,000 2,754E-03 0,01088725 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 2,754E-03 0,01086966 ! antibiotic transport GO:0042891 9 7 0,000 2,754E-03 0,01085213 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 2,754E-03 0,01083466 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 2,754E-03 0,01081724 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 2,754E-03 0,01079987 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 2,754E-03 0,01078257 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 2,754E-03 0,01076531 ! melanin biosynthetic process GO:0042438 10 7 0,000 2,754E-03 0,01074812 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 2,754E-03 0,01073097 ! dopamine biosynthetic process GO:0042416 18 7 0,000 2,754E-03 0,01071389 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 2,754E-03 0,01069685 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 2,754E-03 0,01067987 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 2,754E-03 0,01066295 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 2,754E-03 0,01064608 ! endosome to lysosome transport GO:0008333 12 7 0,000 2,754E-03 0,01062926 ! protein modification by small protein removal GO:0070646 19 7 0,000 2,754E-03 0,01061249 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 2,754E-03 0,01059578 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 2,754E-03 0,01057912 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 2,754E-03 0,01056251 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 2,754E-03 0,01054596 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 2,754E-03 0,01052945 ! muscle adaptation GO:0043500 13 7 0,000 2,754E-03 0,010513 ! embryonic heart tube development GO:0035050 14 7 0,000 2,754E-03 0,0104966 ! retina homeostasis GO:0001895 12 7 0,000 2,754E-03 0,01048025 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 2,754E-03 0,01046395 ! protein amino acid prenylation GO:0018346 19 7 0,000 2,754E-03 0,0104477 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 2,754E-03 0,01043151 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 2,754E-03 0,01041536 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 3,147E-03 0,0118827 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 3,147E-03 0,01186436 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 3,147E-03 0,01184608 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 3,147E-03 0,01182785 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 3,147E-03 0,01180968 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 3,147E-03 0,01179157 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 3,147E-03 0,01177351 ! male meiosis GO:0007140 9 8 0,000 3,147E-03 0,01175551 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 3,147E-03 0,01173756 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 3,147E-03 0,01171967 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 3,147E-03 0,01170183 ! meiotic prophase I GO:0007128 14 8 0,000 3,147E-03 0,01168405 ! response to zinc ion GO:0010043 12 8 0,000 3,147E-03 0,01166632 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 3,147E-03 0,01164864 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 3,147E-03 0,01163102 ! oligopeptide transport GO:0006857 16 8 0,000 3,147E-03 0,01161345 ! actin-myosin filament sliding GO:0033275 13 8 0,000 3,147E-03 0,01159593 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 3,147E-03 0,01157847 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 3,147E-03 0,01156106 ! signal peptide processing GO:0006465 12 8 0,000 3,147E-03 0,0115437 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 3,147E-03 0,01152639 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 3,147E-03 0,01150914 ! macrophage chemotaxis GO:0048246 12 8 0,000 3,147E-03 0,01149193 ! succinate metabolic process GO:0006105 17 8 0,000 3,147E-03 0,01147478 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 3,147E-03 0,01145768 ! membrane hyperpolarization GO:0060081 11 8 0,000 3,147E-03 0,01144063 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 3,147E-03 0,01142363 ! estrogen metabolic process GO:0008210 17 8 0,000 3,147E-03 0,01140668 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 3,147E-03 0,01138978 ! T-helper 1 type immune response GO:0042088 12 8 0,000 3,147E-03 0,01137293 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 3,147E-03 0,01135614 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 3,147E-03 0,01133939 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 3,147E-03 0,01132269 ! reflex GO:0060004 17 8 0,000 3,147E-03 0,01130604 ! endothelial cell differentiation GO:0045446 17 8 0,000 3,147E-03 0,01128943 ! glycerolipid catabolic process GO:0046503 14 8 0,000 3,147E-03 0,01127288 ! hemoglobin metabolic process GO:0020027 14 8 0,000 3,147E-03 0,01125637 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 3,147E-03 0,01123992 ! pigment granule organization GO:0048753 17 8 0,000 3,147E-03 0,01122351 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 3,147E-03 0,01120715 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 3,147E-03 0,01119084 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 3,147E-03 0,01117457 ! astrocyte differentiation GO:0048708 19 8 0,000 3,147E-03 0,01115835 ! histidine catabolic process GO:0006548 10 8 0,000 3,147E-03 0,01114218 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 3,147E-03 0,01112606 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 3,147E-03 0,01110998 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 3,147E-03 0,01109395 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 3,147E-03 0,01107796 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 3,147E-03 0,01106202 ! regulation of pigmentation during development GO:0048070 25 8 0,000 3,147E-03 0,01104613 ! melanin metabolic process GO:0006582 17 8 0,000 3,147E-03 0,01103028 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 3,147E-03 0,01101448 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 3,147E-03 0,01099872 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 3,147E-03 0,01098301 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 3,147E-03 0,01096734 ! macrophage activation GO:0042116 13 8 0,000 3,147E-03 0,01095172 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 3,147E-03 0,01093614 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 3,147E-03 0,0109206 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 3,147E-03 0,01090511 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 3,147E-03 0,01088967 ! purine salvage GO:0043101 12 8 0,000 3,147E-03 0,01087426 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 3,147E-03 0,0108589 ! regulation of vascular permeability GO:0043114 12 8 0,000 3,147E-03 0,01084359 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 3,147E-03 0,01082832 ! osteoblast development GO:0002076 17 8 0,000 3,147E-03 0,01081309 ! positive regulation of vasodilation GO:0045909 14 8 0,000 3,147E-03 0,0107979 ! negative regulation of translational initiation GO:0045947 12 8 0,000 3,147E-03 0,01078275 ! Schwann cell differentiation GO:0014037 21 8 0,000 3,147E-03 0,01076765 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 3,147E-03 0,01075259 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 3,147E-03 0,01073758 ! response to UV-B GO:0010224 17 8 0,000 3,147E-03 0,0107226 ! protein targeting to vacuole GO:0006623 14 8 0,000 3,147E-03 0,01070767 ! protein retention in ER lumen GO:0006621 14 8 0,000 3,147E-03 0,01069277 ! intermediate filament organization GO:0045109 12 8 0,000 3,147E-03 0,01067792 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 3,147E-03 0,01066311 ! cellular extravasation GO:0045123 13 8 0,000 3,147E-03 0,01064834 ! cardiac muscle cell development GO:0055013 14 8 0,000 3,147E-03 0,01063362 ! response to antibiotic GO:0046677 11 8 0,000 3,147E-03 0,01061893 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 3,147E-03 0,01060428 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 3,147E-03 0,01058967 ! DNA topological change GO:0006265 12 8 0,000 3,147E-03 0,01057511 ! response to tropane GO:0014073 15 8 0,000 3,147E-03 0,01056058 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 3,147E-03 0,0105461 ! melanosome transport GO:0032402 13 8 0,000 3,147E-03 0,01053165 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 0,000 3,147E-03 0,01051724 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 3,147E-03 0,01050287 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 3,147E-03 0,01048855 ! mast cell activation GO:0045576 14 8 0,000 3,147E-03 0,01047426 ! multicellular organismal aging GO:0010259 20 8 0,000 3,147E-03 0,01046001 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 3,147E-03 0,01044579 ! gas homeostasis GO:0033483 14 8 0,000 3,147E-03 0,01043162 ! dendrite morphogenesis GO:0048813 14 8 0,000 3,147E-03 0,01041749 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 3,147E-03 0,01040339 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 3,147E-03 0,01038933 ! nucleosome disassembly GO:0006337 14 8 0,000 3,147E-03 0,01037531 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 3,147E-03 0,01036133 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 3,147E-03 0,01034738 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 3,147E-03 0,01033347 ! establishment of chromosome localization GO:0051303 14 8 0,000 3,147E-03 0,0103196 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 3,147E-03 0,01030577 ! intracellular lipid transport GO:0032365 16 8 0,000 3,147E-03 0,01029197 ! response to tumor cell GO:0002347 16 8 0,000 3,147E-03 0,01027821 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 3,147E-03 0,01026449 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 3,147E-03 0,01025081 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 3,147E-03 0,01023716 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 3,147E-03 0,01022354 ! positive regulation of epidermis development GO:0045684 13 8 0,000 3,147E-03 0,01020997 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 3,147E-03 0,01019642 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 3,147E-03 0,01018292 ! hormone catabolic process GO:0042447 17 8 0,000 3,147E-03 0,01016945 ! glycolipid catabolic process GO:0019377 16 8 0,000 3,147E-03 0,01015602 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 3,147E-03 0,01014262 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 3,147E-03 0,01012925 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 3,147E-03 0,01011593 ! positive regulation of glucose import GO:0046326 8 8 0,000 3,147E-03 0,01010263 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 3,147E-03 0,01008938 ! adult feeding behavior GO:0008343 10 8 0,000 3,147E-03 0,01007615 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 3,147E-03 0,01006296 ! ATP catabolic process GO:0006200 11 8 0,000 3,147E-03 0,01004981 ! blastocyst growth GO:0001832 19 8 0,000 3,147E-03 0,01003669 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 3,147E-03 0,0100236 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 3,147E-03 0,01001055 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 3,147E-03 9,998E-03 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 3,147E-03 9,985E-03 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 3,147E-03 9,972E-03 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 3,147E-03 9,959E-03 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 3,147E-03 9,946E-03 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 3,147E-03 9,933E-03 ! amino sugar catabolic process GO:0046348 11 8 0,000 3,147E-03 9,92E-03 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 3,147E-03 9,907E-03 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 3,147E-03 9,895E-03 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 3,147E-03 9,882E-03 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 3,147E-03 9,869E-03 ! behavioral response to nicotine GO:0035095 12 8 0,000 3,147E-03 9,857E-03 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 3,147E-03 9,844E-03 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 3,147E-03 9,831E-03 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 3,147E-03 9,819E-03 ! NAD biosynthetic process GO:0009435 17 8 0,000 3,147E-03 9,806E-03 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 3,147E-03 9,794E-03 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 3,147E-03 9,781E-03 ! axon extension GO:0048675 16 9 0,000 3,54E-03 0,01098797 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 3,54E-03 0,01097403 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 3,54E-03 0,01096012 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 3,54E-03 0,01094625 ! pentose-phosphate shunt GO:0006098 16 9 0,000 3,54E-03 0,01093241 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 3,54E-03 0,01091861 ! cell proliferation in forebrain GO:0021846 18 9 0,000 3,54E-03 0,01090484 ! neutral lipid catabolic process GO:0046461 14 9 0,000 3,54E-03 0,0108911 ! reproductive behavior GO:0019098 22 9 0,000 3,54E-03 0,0108774 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 3,54E-03 0,01086374 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 3,54E-03 0,01085011 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 3,54E-03 0,01083651 ! UTP metabolic process GO:0046051 10 9 0,000 3,54E-03 0,01082295 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 3,54E-03 0,01080942 ! induction of positive chemotaxis GO:0050930 17 9 0,000 3,54E-03 0,01079592 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 3,54E-03 0,01078246 ! artery development GO:0060840 25 9 0,000 3,54E-03 0,01076904 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 3,54E-03 0,01075564 ! regulation of glycolysis GO:0006110 20 9 0,000 3,54E-03 0,01074228 ! cerebral cortex cell migration GO:0021795 18 9 0,000 3,54E-03 0,01072895 ! equilibrioception GO:0050957 20 9 0,000 3,54E-03 0,01071566 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 3,54E-03 0,0107024 ! chemosensory behavior GO:0007635 21 9 0,000 3,54E-03 0,01068917 ! microtubule bundle formation GO:0001578 22 9 0,000 3,54E-03 0,01067597 ! middle ear morphogenesis GO:0042474 14 9 0,000 3,54E-03 0,01066281 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 3,54E-03 0,01064967 ! leukocyte degranulation GO:0043299 16 9 0,000 3,54E-03 0,01063658 ! ganglioside metabolic process GO:0001573 22 9 0,000 3,54E-03 0,01062351 ! negative regulation of endocytosis GO:0045806 12 9 0,000 3,54E-03 0,01061047 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 3,54E-03 0,01059747 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 3,54E-03 0,0105845 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 3,54E-03 0,01057156 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 3,54E-03 0,01055865 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 3,54E-03 0,01054578 ! protein targeting to ER GO:0045047 25 9 0,000 3,54E-03 0,01053293 ! ceramide biosynthetic process GO:0046513 20 9 0,000 3,54E-03 0,01052012 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 3,54E-03 0,01050733 ! T cell selection GO:0045058 27 9 0,000 3,54E-03 0,01049458 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 0,000 3,54E-03 0,01048186 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 3,54E-03 0,01046917 ! glycine catabolic process GO:0006546 15 9 0,000 3,54E-03 0,01045651 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 3,54E-03 0,01044388 ! endosome organization GO:0007032 20 9 0,000 3,54E-03 0,01043129 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 3,54E-03 0,01041872 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 3,54E-03 0,01040618 ! regulation of type I interferon production GO:0032479 12 9 0,000 3,54E-03 0,01039367 ! mannose metabolic process GO:0006013 13 9 0,000 3,54E-03 0,0103812 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 3,54E-03 0,01036875 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 3,54E-03 0,01035633 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 3,54E-03 0,01034394 ! Rac protein signal transduction GO:0016601 20 9 0,000 3,54E-03 0,01033158 ! receptor clustering GO:0043113 20 9 0,000 3,54E-03 0,01031926 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 3,54E-03 0,01030696 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 3,54E-03 0,01029469 ! retinol metabolic process GO:0042572 20 9 0,000 3,54E-03 0,01028244 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 3,54E-03 0,01027023 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 3,54E-03 0,01025805 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 3,54E-03 0,0102459 ! macrophage differentiation GO:0030225 15 9 0,000 3,54E-03 0,01023377 ! oligodendrocyte development GO:0014003 11 9 0,000 3,54E-03 0,01022167 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 3,54E-03 0,01020961 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 3,54E-03 0,01019757 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 3,54E-03 0,01018555 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 3,54E-03 0,01017357 ! response to amine stimulus GO:0014075 13 9 0,000 3,54E-03 0,01016162 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 3,54E-03 0,01014969 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 3,54E-03 0,01013779 ! erythrocyte development GO:0048821 17 9 0,000 3,54E-03 0,01012592 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 3,54E-03 0,01011408 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 3,54E-03 0,01010226 ! renal water homeostasis GO:0003091 15 9 0,000 3,54E-03 0,01009047 ! postreplication repair GO:0006301 25 9 0,000 3,54E-03 0,01007871 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 3,54E-03 0,01006698 ! icosanoid secretion GO:0032309 15 9 0,000 3,54E-03 0,01005527 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 3,54E-03 0,0100436 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 3,54E-03 0,01003194 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 3,54E-03 0,01002032 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 3,54E-03 0,01000872 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 3,54E-03 9,997E-03 ! sterol catabolic process GO:0016127 14 9 0,000 3,54E-03 9,986E-03 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 3,54E-03 9,974E-03 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 3,54E-03 9,963E-03 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 3,54E-03 9,951E-03 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 3,54E-03 9,94E-03 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 3,54E-03 9,928E-03 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 3,54E-03 9,917E-03 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 3,54E-03 9,906E-03 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 3,54E-03 9,894E-03 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 3,54E-03 9,883E-03 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 3,54E-03 9,872E-03 ! regulation of synaptogenesis GO:0051963 15 9 0,000 3,54E-03 9,86E-03 ! purine base metabolic process GO:0006144 25 9 0,000 3,54E-03 9,849E-03 ! pigment granule transport GO:0051904 17 9 0,000 3,54E-03 9,838E-03 ! regulation of telomere maintenance GO:0032204 17 9 0,000 3,54E-03 9,827E-03 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 3,54E-03 9,816E-03 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 3,54E-03 9,804E-03 ! regulation of muscle adaptation GO:0043502 14 9 0,000 3,54E-03 9,793E-03 ! regulation of amino acid transport GO:0051955 12 9 0,000 3,54E-03 9,782E-03 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 3,54E-03 9,771E-03 ! mitochondrion localization GO:0051646 18 9 0,000 3,54E-03 9,76E-03 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 3,932E-03 0,01083046 ! regulation of developmental growth GO:0048638 16 10 0,000 3,932E-03 0,01081826 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 0,000 3,932E-03 0,01080609 ! autophagic vacuole formation GO:0000045 17 10 0,000 3,932E-03 0,01079395 ! negative regulation of blood pressure GO:0045776 26 10 0,000 3,932E-03 0,01078184 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 3,932E-03 0,01076975 ! associative learning GO:0008306 21 10 0,000 3,932E-03 0,01075769 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 3,932E-03 0,01074566 ! regulation of phosphatase activity GO:0010921 28 10 0,000 3,932E-03 0,01073365 ! phosphate transport GO:0006817 24 10 0,000 3,932E-03 0,01072167 ! cell volume homeostasis GO:0006884 17 10 0,000 3,932E-03 0,01070972 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 3,932E-03 0,01069779 ! CTP metabolic process GO:0046036 11 10 0,000 3,932E-03 0,01068589 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 3,932E-03 0,01067402 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 3,932E-03 0,01066217 ! GTP metabolic process GO:0046039 11 10 0,000 3,932E-03 0,01065035 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 3,932E-03 0,01063856 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 3,932E-03 0,01062679 ! social behavior GO:0035176 29 10 0,000 3,932E-03 0,01061505 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 3,932E-03 0,01060333 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 3,932E-03 0,01059164 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 3,932E-03 0,01057997 ! androgen metabolic process GO:0008209 17 10 0,000 3,932E-03 0,01056834 ! phospholipid efflux GO:0033700 19 10 0,000 3,932E-03 0,01055672 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 3,932E-03 0,01054513 ! bile acid and bile salt transport GO:0015721 15 10 0,000 3,932E-03 0,01053357 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 3,932E-03 0,01052203 ! positive regulation of heart contraction GO:0045823 17 10 0,000 3,932E-03 0,01051052 ! lung alveolus development GO:0048286 26 10 0,000 3,932E-03 0,01049903 ! pathogenesis GO:0009405 17 10 0,000 3,932E-03 0,01048757 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 3,932E-03 0,01047614 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 3,932E-03 0,01046472 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 3,932E-03 0,01045334 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 3,932E-03 0,01044197 ! endoderm development GO:0007492 18 10 0,000 3,932E-03 0,01043064 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 3,932E-03 0,01041932 ! arginine catabolic process GO:0006527 17 10 0,000 3,932E-03 0,01040804 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 3,932E-03 0,01039677 ! proline metabolic process GO:0006560 13 10 0,000 3,932E-03 0,01038553 ! glucan biosynthetic process GO:0009250 14 10 0,000 3,932E-03 0,01037432 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 3,932E-03 0,01036312 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 3,932E-03 0,01035196 ! V(D)J recombination GO:0033151 34 10 0,000 3,932E-03 0,01034081 ! reverse cholesterol transport GO:0043691 19 10 0,000 3,932E-03 0,0103297 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 3,932E-03 0,0103186 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 3,932E-03 0,01030753 ! B cell proliferation GO:0042100 19 10 0,000 3,932E-03 0,01029648 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 3,932E-03 0,01028546 ! regulation of sodium ion transport GO:0002028 26 10 0,000 3,932E-03 0,01027446 ! multicellular organism growth GO:0035264 19 10 0,000 3,932E-03 0,01026348 ! phagocytosis, engulfment GO:0006911 33 10 0,000 3,932E-03 0,01025253 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 3,932E-03 0,0102416 ! ruffle organization GO:0031529 17 10 0,000 3,932E-03 0,01023069 ! epithelial cell development GO:0002064 21 10 0,000 3,932E-03 0,0102198 ! lens development in camera-type eye GO:0002088 17 10 0,000 3,932E-03 0,01020894 ! retinoic acid metabolic process GO:0042573 14 10 0,000 3,932E-03 0,01019811 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 3,932E-03 0,01018729 ! positive regulation of translational initiation GO:0045948 12 10 0,000 3,932E-03 0,0101765 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 3,932E-03 0,01016573 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 3,932E-03 0,01015499 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 3,932E-03 0,01014426 ! motor axon guidance GO:0008045 22 10 0,000 3,932E-03 0,01013356 ! copper ion homeostasis GO:0055070 13 10 0,000 3,932E-03 0,01012288 ! regulation of bone resorption GO:0045124 25 10 0,000 3,932E-03 0,01011223 ! protein heterooligomerization GO:0051291 17 10 0,000 3,932E-03 0,01010159 ! regulation of gliogenesis GO:0014013 23 10 0,000 3,932E-03 0,01009098 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 3,932E-03 0,0100804 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 3,932E-03 0,01006983 ! segment specification GO:0007379 15 10 0,000 3,932E-03 0,01005928 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 3,932E-03 0,01004876 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 3,932E-03 0,01003826 ! blastoderm segmentation GO:0007350 19 10 0,000 3,932E-03 0,01002778 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 3,932E-03 0,01001733 ! response to dsRNA GO:0043331 23 10 0,000 3,932E-03 0,01000689 ! DNA ligation GO:0006266 18 10 0,000 3,932E-03 9,996E-03 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 3,932E-03 9,986E-03 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 3,932E-03 9,976E-03 ! melanosome localization GO:0032400 16 10 0,000 3,932E-03 9,965E-03 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 3,932E-03 9,955E-03 ! regulation of B cell differentiation GO:0045577 24 10 0,000 3,932E-03 9,945E-03 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 3,932E-03 9,934E-03 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 3,932E-03 9,924E-03 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 3,932E-03 9,914E-03 ! induction of an organ GO:0001759 17 10 0,000 3,932E-03 9,904E-03 ! leukocyte activation during immune response GO:0002366 15 10 0,000 3,932E-03 9,894E-03 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 3,932E-03 9,883E-03 ! protein sumoylation GO:0016925 17 10 0,000 3,932E-03 9,873E-03 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 3,932E-03 9,863E-03 ! hindbrain morphogenesis GO:0021575 19 10 0,000 3,932E-03 9,853E-03 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 3,932E-03 9,843E-03 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 3,932E-03 9,833E-03 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 3,932E-03 9,823E-03 ! salivary gland development GO:0007431 28 10 0,000 3,932E-03 9,813E-03 ! ubiquinone metabolic process GO:0006743 17 10 0,000 3,932E-03 9,803E-03 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 3,932E-03 9,793E-03 ! midbrain development GO:0030901 14 10 0,000 3,932E-03 9,783E-03 ! musculoskeletal movement GO:0050881 16 10 0,000 3,932E-03 9,773E-03 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 3,932E-03 9,763E-03 ! methionine biosynthetic process GO:0009086 21 10 0,000 3,932E-03 9,753E-03 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 3,932E-03 9,743E-03 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 3,932E-03 9,733E-03 ! quaternary ammonium group transport GO:0015697 22 10 0,000 3,932E-03 9,723E-03 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 3,932E-03 9,713E-03 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 3,932E-03 9,704E-03 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 3,932E-03 9,694E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 3,932E-03 9,684E-03 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 3,932E-03 9,674E-03 ! establishment of pigment granule localization GO:0051905 18 10 0,000 3,932E-03 9,665E-03 ! blastocyst formation GO:0001825 18 10 0,000 3,932E-03 9,655E-03 ! regulation of fibrinolysis GO:0051917 20 10 0,000 3,932E-03 9,645E-03 ! cerebellar cortex development GO:0021695 16 10 0,000 3,932E-03 9,636E-03 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 3,932E-03 9,626E-03 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 3,932E-03 9,616E-03 ! response to nicotine GO:0035094 20 10 0,000 3,932E-03 9,607E-03 ! negative regulation of immune effector process GO:0002698 23 10 0,000 3,932E-03 9,597E-03 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 3,932E-03 9,587E-03 ! negative regulation of muscle development GO:0048635 27 11 0,000 4,325E-03 0,01053375 ! respiratory burst GO:0045730 17 11 0,000 4,325E-03 0,01052325 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 4,325E-03 0,01051278 ! neuron fate specification GO:0048665 18 11 0,000 4,325E-03 0,01050233 ! telencephalon cell migration GO:0022029 23 11 0,000 4,325E-03 0,0104919 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 4,325E-03 0,01048149 ! thyroid gland development GO:0030878 26 11 0,000 4,325E-03 0,01047111 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 4,325E-03 0,01046074 ! synapsis GO:0007129 14 11 0,000 4,325E-03 0,01045039 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 4,325E-03 0,01044007 ! Golgi vesicle budding GO:0048194 26 11 0,000 4,325E-03 0,01042976 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 4,325E-03 0,01041947 ! response to pain GO:0048265 27 11 0,000 4,325E-03 0,01040921 ! detection of mechanical stimulus GO:0050982 22 11 0,000 4,325E-03 0,01039896 ! keratinocyte proliferation GO:0043616 19 11 0,000 4,325E-03 0,01038874 ! blood vessel remodeling GO:0001974 30 11 0,000 4,325E-03 0,01037853 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 4,325E-03 0,01036835 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 4,325E-03 0,01035818 ! bone resorption GO:0045453 16 11 0,000 4,325E-03 0,01034804 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 4,325E-03 0,01033791 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 4,325E-03 0,01032781 ! negative regulation of proteolysis GO:0045861 25 11 0,000 4,325E-03 0,01031772 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 4,325E-03 0,01030766 ! melanocyte differentiation GO:0030318 20 11 0,000 4,325E-03 0,01029761 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 4,325E-03 0,01028758 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 4,325E-03 0,01027757 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 4,325E-03 0,01026759 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 4,325E-03 0,01025762 ! regulation of intracellular pH GO:0051453 21 11 0,000 4,325E-03 0,01024767 ! substrate-bound cell migration GO:0006929 14 11 0,000 4,325E-03 0,01023774 ! UV protection GO:0009650 20 11 0,000 4,325E-03 0,01022783 ! adult heart development GO:0007512 16 11 0,000 4,325E-03 0,01021794 ! chondrocyte differentiation GO:0002062 27 11 0,000 4,325E-03 0,01020806 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 4,325E-03 0,01019821 ! macroautophagy GO:0016236 19 11 0,000 4,325E-03 0,01018838 ! temperature homeostasis GO:0001659 18 11 0,000 4,325E-03 0,01017856 ! behavioral fear response GO:0001662 27 11 0,000 4,325E-03 0,01016876 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 4,325E-03 0,01015899 ! negative regulation of ossification GO:0030279 27 11 0,000 4,325E-03 0,01014923 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 4,325E-03 0,01013949 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 4,325E-03 0,01012977 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 4,325E-03 0,01012006 ! alpha-beta T cell activation GO:0046631 26 11 0,000 4,325E-03 0,01011038 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 4,325E-03 0,01010071 ! regulation of organ growth GO:0046620 14 11 0,000 4,325E-03 0,01009107 ! pigment granule localization GO:0051875 20 11 0,000 4,325E-03 0,01008144 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 4,325E-03 0,01007183 ! vasoconstriction GO:0042310 20 11 0,000 4,325E-03 0,01006223 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 4,325E-03 0,01005266 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 4,325E-03 0,0100431 ! embryonic axis specification GO:0000578 19 11 0,000 4,325E-03 0,01003357 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 4,325E-03 0,01002405 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 4,325E-03 0,01001455 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 4,325E-03 0,01000506 ! nitric oxide metabolic process GO:0046209 17 11 0,000 4,325E-03 9,996E-03 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 4,325E-03 9,986E-03 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 4,325E-03 9,977E-03 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 4,325E-03 9,967E-03 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 4,325E-03 9,958E-03 ! prophase GO:0051324 17 11 0,000 4,325E-03 9,949E-03 ! neuroblast proliferation GO:0007405 25 11 0,000 4,325E-03 9,939E-03 ! nucleosome positioning GO:0016584 15 11 0,000 4,325E-03 9,93E-03 ! regulation of isotype switching GO:0045191 24 11 0,000 4,325E-03 9,921E-03 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 4,325E-03 9,911E-03 ! negative regulation of neurological system process GO:0031645 21 11 0,000 4,325E-03 9,902E-03 ! apical protein localization GO:0045176 18 11 0,000 4,325E-03 9,893E-03 ! acid secretion GO:0046717 20 11 0,000 4,325E-03 9,883E-03 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 4,325E-03 9,874E-03 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 4,325E-03 9,865E-03 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 4,325E-03 9,856E-03 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 4,325E-03 9,847E-03 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 4,325E-03 9,837E-03 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 4,325E-03 9,828E-03 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 4,325E-03 9,819E-03 ! cholesterol efflux GO:0033344 21 11 0,000 4,325E-03 9,81E-03 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 4,325E-03 9,801E-03 ! oocyte development GO:0048599 20 11 0,000 4,325E-03 9,792E-03 ! negative regulation of glucose import GO:0046325 18 11 0,000 4,325E-03 9,783E-03 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 4,325E-03 9,774E-03 ! embryonic gut development GO:0048566 19 11 0,000 4,325E-03 9,765E-03 ! regulation of organic acid transport GO:0032890 19 11 0,000 4,325E-03 9,756E-03 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 4,325E-03 9,747E-03 ! activation of innate immune response GO:0002218 16 11 0,000 4,325E-03 9,738E-03 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 4,325E-03 9,729E-03 ! cardiac cell differentiation GO:0035051 36 11 0,000 4,325E-03 9,72E-03 ! lysogeny GO:0030069 22 11 0,000 4,325E-03 9,711E-03 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 4,325E-03 9,702E-03 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 4,325E-03 9,693E-03 ! sequestering of metal ion GO:0051238 15 11 0,000 4,325E-03 9,684E-03 ! regulation of embryonic development GO:0045995 35 11 0,000 4,325E-03 9,675E-03 ! nucleus localization GO:0051647 22 11 0,000 4,325E-03 9,666E-03 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 4,717E-03 0,01053357 ! positive regulation of blood pressure GO:0045777 18 12 0,000 4,717E-03 0,01052395 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 4,717E-03 0,01051435 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 4,717E-03 0,01050476 ! virus-host interaction GO:0019048 30 12 0,000 4,717E-03 0,0104952 ! regulation of B cell proliferation GO:0030888 22 12 0,000 4,717E-03 0,01048565 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 4,717E-03 0,01047611 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 4,717E-03 0,0104666 ! protein complex disassembly GO:0043241 28 12 0,000 4,717E-03 0,0104571 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 4,717E-03 0,01044762 ! regulation of cell projection assembly GO:0060491 33 12 0,000 4,717E-03 0,01043816 ! hippocampus development GO:0021766 29 12 0,000 4,717E-03 0,01042871 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 4,717E-03 0,01041928 ! cytokine biosynthetic process GO:0042089 23 12 0,000 4,717E-03 0,01040987 ! T cell proliferation GO:0042098 32 12 0,000 4,717E-03 0,01040047 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 4,717E-03 0,0103911 ! regulation of exit from mitosis GO:0007096 19 12 0,000 4,717E-03 0,01038173 ! ventral spinal cord development GO:0021517 25 12 0,000 4,717E-03 0,01037239 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 4,717E-03 0,01036306 ! drug transport GO:0015893 16 12 0,000 4,717E-03 0,01035375 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 4,717E-03 0,01034446 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 4,717E-03 0,01033518 ! tyrosine metabolic process GO:0006570 19 12 0,000 4,717E-03 0,01032592 ! polyamine metabolic process GO:0006595 18 12 0,000 4,717E-03 0,01031667 ! focal adhesion formation GO:0048041 37 12 0,000 4,717E-03 0,01030745 ! mitotic spindle organization GO:0007052 23 12 0,000 4,717E-03 0,01029824 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 4,717E-03 0,01028904 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 4,717E-03 0,01027986 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 4,717E-03 0,0102707 ! lipid digestion GO:0044241 21 12 0,000 4,717E-03 0,01026155 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 4,717E-03 0,01025242 ! entry into host cell GO:0030260 34 12 0,000 4,717E-03 0,01024331 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 4,717E-03 0,01023421 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 4,717E-03 0,01022513 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 4,717E-03 0,01021607 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 4,717E-03 0,01020702 ! protein targeting to peroxisome GO:0006625 27 12 0,000 4,717E-03 0,01019799 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 4,717E-03 0,01018897 ! regulation of phagocytosis GO:0050764 17 12 0,000 4,717E-03 0,01017997 ! snRNA metabolic process GO:0016073 30 12 0,000 4,717E-03 0,01017098 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 4,717E-03 0,01016202 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 4,717E-03 0,01015306 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 4,717E-03 0,01014412 ! cranial nerve development GO:0021545 23 12 0,000 4,717E-03 0,0101352 ! fucose catabolic process GO:0019317 25 12 0,000 4,717E-03 0,0101263 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 4,717E-03 0,01011741 ! histone acetylation GO:0016573 27 12 0,000 4,717E-03 0,01010853 ! mRNA polyadenylation GO:0006378 24 12 0,000 4,717E-03 0,01009967 ! autonomic nervous system development GO:0048483 24 12 0,000 4,717E-03 0,01009083 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 4,717E-03 0,010082 ! zymogen activation GO:0031638 18 12 0,000 4,717E-03 0,01007319 ! peptidyl-lysine modification GO:0018205 21 12 0,000 4,717E-03 0,01006439 ! T cell homeostasis GO:0043029 28 12 0,000 4,717E-03 0,01005561 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 4,717E-03 0,01004684 ! glutathione biosynthetic process GO:0006750 15 12 0,000 4,717E-03 0,01003809 ! regulation of leukocyte migration GO:0002685 29 12 0,000 4,717E-03 0,01002935 ! oocyte differentiation GO:0009994 21 12 0,000 4,717E-03 0,01002063 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 4,717E-03 0,01001192 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 4,717E-03 0,01000323 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 4,717E-03 9,995E-03 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 4,717E-03 9,986E-03 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 4,717E-03 9,977E-03 ! defense response to fungus GO:0050832 15 12 0,000 4,717E-03 9,969E-03 ! developmental induction GO:0031128 22 12 0,000 4,717E-03 9,96E-03 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 4,717E-03 9,951E-03 ! lamellipodium assembly GO:0030032 24 12 0,000 4,717E-03 9,943E-03 ! response to cold GO:0009409 17 12 0,000 4,717E-03 9,934E-03 ! establishment of cell polarity GO:0030010 21 12 0,000 4,717E-03 9,926E-03 ! regulation of synapse organization GO:0050807 18 12 0,000 4,717E-03 9,917E-03 ! localization within membrane GO:0051668 26 12 0,000 4,717E-03 9,909E-03 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 5,109E-03 0,01072316 ! cGMP metabolic process GO:0046068 18 13 0,000 5,109E-03 0,01071395 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 5,109E-03 0,01070476 ! regulation of chemokine production GO:0032642 18 13 0,000 5,109E-03 0,01069559 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 5,109E-03 0,01068643 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 5,109E-03 0,01067729 ! peroxisomal transport GO:0043574 28 13 0,000 5,109E-03 0,01066817 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 5,109E-03 0,01065906 ! cartilage condensation GO:0001502 22 13 0,000 5,109E-03 0,01064996 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 5,109E-03 0,01064088 ! organelle fusion GO:0048284 36 13 0,000 5,109E-03 0,01063182 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 5,109E-03 0,01062277 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 5,109E-03 0,01061374 ! pseudouridine synthesis GO:0001522 19 13 0,000 5,109E-03 0,01060472 ! endocrine pancreas development GO:0031018 25 13 0,000 5,109E-03 0,01059572 ! positive regulation of cell growth GO:0030307 24 13 0,000 5,109E-03 0,01058673 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 5,109E-03 0,01057776 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 5,109E-03 0,0105688 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 5,109E-03 0,01055986 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 5,109E-03 0,01055093 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 5,109E-03 0,01054202 ! methionine metabolic process GO:0006555 31 13 0,000 5,109E-03 0,01053313 ! plasma membrane organization GO:0007009 27 13 0,000 5,109E-03 0,01052424 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 5,109E-03 0,01051538 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 5,109E-03 0,01050653 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 5,109E-03 0,01049769 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 5,109E-03 0,01048887 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 5,109E-03 0,01048006 ! cytokine metabolic process GO:0042107 24 13 0,000 5,109E-03 0,01047127 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 5,109E-03 0,01046249 ! exocrine system development GO:0035272 34 13 0,000 5,109E-03 0,01045373 ! asymmetric protein localization GO:0008105 24 13 0,000 5,109E-03 0,01044498 ! membrane protein proteolysis GO:0033619 33 13 0,000 5,109E-03 0,01043625 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 5,109E-03 0,01042753 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 5,109E-03 0,01041883 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 5,109E-03 0,01041014 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 5,109E-03 0,01040146 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 5,109E-03 0,0103928 ! protein homotetramerization GO:0051289 24 13 0,000 5,109E-03 0,01038415 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 5,109E-03 0,01037552 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 5,109E-03 0,01036691 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 5,109E-03 0,0103583 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 5,109E-03 0,01034971 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 5,109E-03 0,01034114 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 5,109E-03 0,01033258 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 5,109E-03 0,01032403 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 5,109E-03 0,0103155 ! histone methylation GO:0016571 29 13 0,000 5,109E-03 0,01030698 ! chromatin silencing GO:0006342 29 13 0,000 5,109E-03 0,01029848 ! gland morphogenesis GO:0022612 31 13 0,000 5,109E-03 0,01028999 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 5,109E-03 0,01028151 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 5,109E-03 0,01027305 ! regulation of epidermis development GO:0045682 19 13 0,000 5,109E-03 0,0102646 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 5,109E-03 0,01025617 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 5,109E-03 0,01024775 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 5,109E-03 0,01023934 ! spleen development GO:0048536 24 13 0,000 5,109E-03 0,01023095 ! regulation of mRNA stability GO:0043488 32 13 0,000 5,109E-03 0,01022257 ! digestive tract morphogenesis GO:0048546 31 13 0,000 5,109E-03 0,0102142 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 5,109E-03 0,01020585 ! anterior/posterior axis specification GO:0009948 22 13 0,000 5,109E-03 0,01019751 ! regulation of RNA splicing GO:0043484 22 13 0,000 5,109E-03 0,01018919 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 5,109E-03 0,01018088 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 5,109E-03 0,01017258 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 5,109E-03 0,01016429 ! mRNA 3'-end processing GO:0031124 25 13 0,000 5,109E-03 0,01015602 ! insulin secretion GO:0030073 24 13 0,000 5,109E-03 0,01014777 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 5,109E-03 0,01013952 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 5,109E-03 0,01013129 ! acrosome reaction GO:0007340 19 13 0,000 5,109E-03 0,01012308 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 5,109E-03 0,01011487 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 5,109E-03 0,01010668 ! rRNA transcription GO:0009303 28 14 0,000 5,501E-03 0,01087333 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 5,501E-03 0,01086454 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 5,501E-03 0,01085576 ! water transport GO:0006833 21 14 0,000 5,501E-03 0,010847 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 5,501E-03 0,01083825 ! non-recombinational repair GO:0000726 29 14 0,000 5,501E-03 0,01082952 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 5,501E-03 0,0108208 ! retina development in camera-type eye GO:0060041 28 14 0,000 5,501E-03 0,01081209 ! hair follicle morphogenesis GO:0031069 27 14 0,000 5,501E-03 0,0108034 ! RNA polyadenylation GO:0043631 32 14 0,000 5,501E-03 0,01079472 ! lipid localization GO:0010876 32 14 0,000 5,501E-03 0,01078606 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 5,501E-03 0,01077741 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 5,501E-03 0,01076878 ! regulated secretory pathway GO:0045055 24 14 0,000 5,501E-03 0,01076015 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 5,501E-03 0,01075155 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 5,501E-03 0,01074295 ! arginine metabolic process GO:0006525 21 14 0,000 5,501E-03 0,01073437 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 5,501E-03 0,0107258 ! cell-cell junction assembly GO:0007043 32 14 0,000 5,501E-03 0,01071725 ! regulation of heart rate GO:0002027 25 14 0,000 5,501E-03 0,01070871 ! fear response GO:0042596 34 14 0,000 5,501E-03 0,01070018 ! organic alcohol transport GO:0015850 29 14 0,000 5,501E-03 0,01069167 ! negative regulation of caspase activity GO:0043154 23 14 0,000 5,501E-03 0,01068317 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 5,501E-03 0,01067469 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 5,501E-03 0,01066622 ! neutral amino acid transport GO:0015804 28 14 0,000 5,501E-03 0,01065776 ! bone mineralization GO:0030282 18 14 0,000 5,501E-03 0,01064931 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 5,501E-03 0,01064088 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 5,501E-03 0,01063246 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 5,501E-03 0,01062406 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 5,501E-03 0,01061567 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 5,501E-03 0,01060729 ! regulation of cellular pH GO:0030641 27 14 0,000 5,501E-03 0,01059892 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 5,501E-03 0,01059057 ! ribosome assembly GO:0042255 18 14 0,000 5,501E-03 0,01058223 ! cerebellum development GO:0021549 23 14 0,000 5,501E-03 0,0105739 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 5,501E-03 0,01056559 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 5,501E-03 0,01055729 ! negative regulation of protein secretion GO:0050709 30 14 0,000 5,501E-03 0,010549 ! response to gamma radiation GO:0010332 30 14 0,000 5,501E-03 0,01054073 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 5,501E-03 0,01053247 ! NADP metabolic process GO:0006739 24 14 0,000 5,501E-03 0,01052422 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 5,501E-03 0,01051599 ! oxygen transport GO:0015671 22 14 0,000 5,501E-03 0,01050777 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 5,501E-03 0,01049956 ! male genitalia development GO:0030539 26 14 0,000 5,501E-03 0,01049136 ! regulation of RNA stability GO:0043487 33 14 0,000 5,501E-03 0,01048318 ! regulation of axon extension GO:0030516 43 14 0,000 5,501E-03 0,01047501 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 5,501E-03 0,01046685 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 5,501E-03 0,0104587 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 5,501E-03 0,01045057 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 5,893E-03 0,01118629 ! lactation GO:0007595 30 15 0,000 5,893E-03 0,01117761 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 5,893E-03 0,01116894 ! reproductive cellular process GO:0048610 22 15 0,000 5,893E-03 0,01116028 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 5,893E-03 0,01115163 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 5,893E-03 0,011143 ! superoxide anion generation GO:0042554 22 15 0,000 5,893E-03 0,01113438 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 5,893E-03 0,01112578 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 5,893E-03 0,01111719 ! phospholipid catabolic process GO:0009395 27 15 0,000 5,893E-03 0,01110861 ! copper ion transport GO:0006825 22 15 0,000 5,893E-03 0,01110005 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 5,893E-03 0,01109149 ! cardiac muscle contraction GO:0060048 28 15 0,000 5,893E-03 0,01108296 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 5,893E-03 0,01107443 ! sulfate transport GO:0008272 27 15 0,000 5,893E-03 0,01106592 ! response to cAMP GO:0051591 25 15 0,000 5,893E-03 0,01105742 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 5,893E-03 0,01104893 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 5,893E-03 0,01104046 ! regulation of mRNA processing GO:0050684 26 15 0,000 5,893E-03 0,011032 ! response to hexose stimulus GO:0009746 25 15 0,000 5,893E-03 0,01102355 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 5,893E-03 0,01101512 ! glycoprotein catabolic process GO:0006516 33 15 0,000 5,893E-03 0,0110067 ! vesicle coating GO:0006901 38 15 0,000 5,893E-03 0,01099829 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 5,893E-03 0,01098989 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 5,893E-03 0,01098151 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 5,893E-03 0,01097314 ! regulation of exocytosis GO:0017157 26 15 0,000 5,893E-03 0,01096478 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 5,893E-03 0,01095644 ! G1/S transition checkpoint GO:0031575 37 15 0,000 5,893E-03 0,01094811 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 5,893E-03 0,01093979 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 5,893E-03 0,01093148 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 5,893E-03 0,01092319 ! regulation of vasodilation GO:0042312 27 15 0,000 5,893E-03 0,0109149 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 5,893E-03 0,01090664 ! histone deacetylation GO:0016575 24 15 0,000 5,893E-03 0,01089838 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 5,893E-03 0,01089014 ! water homeostasis GO:0030104 28 15 0,000 5,893E-03 0,0108819 ! cofactor transport GO:0051181 30 15 0,000 5,893E-03 0,01087369 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 5,893E-03 0,01086548 ! muscle maintenance GO:0046716 26 15 0,000 5,893E-03 0,01085728 ! protein-chromophore linkage GO:0018298 25 15 0,000 5,893E-03 0,0108491 ! intestinal absorption GO:0050892 31 15 0,000 5,893E-03 0,01084093 ! dopamine metabolic process GO:0042417 35 15 0,000 5,893E-03 0,01083278 ! cAMP biosynthetic process GO:0006171 25 15 0,000 5,893E-03 0,01082463 ! heme biosynthetic process GO:0006783 33 15 0,000 5,893E-03 0,0108165 ! cell killing GO:0001906 32 15 0,000 5,893E-03 0,01080838 ! lymphocyte homeostasis GO:0002260 33 15 0,000 5,893E-03 0,01080027 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 5,893E-03 0,01079217 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 5,893E-03 0,01078409 ! L-fucose metabolic process GO:0042354 33 15 0,000 5,893E-03 0,01077602 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 5,893E-03 0,01076796 ! actin filament polymerization GO:0030041 27 15 0,000 5,893E-03 0,01075991 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 5,893E-03 0,01075187 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 6,285E-03 0,01145801 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 6,285E-03 0,01144947 ! positive regulation of cell size GO:0045793 29 16 0,000 6,285E-03 0,01144094 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 6,285E-03 0,01143242 ! dicarboxylic acid transport GO:0006835 47 16 0,000 6,285E-03 0,01142391 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 6,285E-03 0,01141542 ! bone remodeling GO:0046849 28 16 0,000 6,285E-03 0,01140694 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 6,285E-03 0,01139847 ! heterophilic cell adhesion GO:0007157 43 16 0,000 6,285E-03 0,01139001 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 6,285E-03 0,01138157 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 6,285E-03 0,01137314 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 6,285E-03 0,01136472 ! positive regulation of ion transport GO:0043270 23 16 0,000 6,285E-03 0,01135631 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 6,285E-03 0,01134792 ! startle response GO:0001964 28 16 0,000 6,285E-03 0,01133954 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 6,285E-03 0,01133117 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 6,285E-03 0,01132281 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 6,285E-03 0,01131447 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 6,285E-03 0,01130614 ! protein polyubiquitination GO:0000209 41 16 0,000 6,285E-03 0,01129782 ! glutamate metabolic process GO:0006536 25 16 0,000 6,285E-03 0,01128951 ! pituitary gland development GO:0021983 30 16 0,000 6,285E-03 0,01128122 ! response to osmotic stress GO:0006970 27 16 0,000 6,285E-03 0,01127293 ! lysosomal transport GO:0007041 31 16 0,000 6,285E-03 0,01126466 ! fructose metabolic process GO:0006000 25 16 0,000 6,285E-03 0,01125641 ! L-amino acid transport GO:0015807 33 16 0,000 6,285E-03 0,01124816 ! stem cell development GO:0048864 46 16 0,000 6,285E-03 0,01123992 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 6,285E-03 0,0112317 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 6,285E-03 0,01122349 ! intermediate filament-based process GO:0045103 36 16 0,000 6,285E-03 0,01121529 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 6,285E-03 0,01120711 ! negative regulation of immune response GO:0050777 38 16 0,000 6,285E-03 0,01119893 ! axon cargo transport GO:0008088 46 16 0,000 6,285E-03 0,01119077 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 6,285E-03 0,01118262 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 6,285E-03 0,01117448 ! DNA replication initiation GO:0006270 28 16 0,000 6,285E-03 0,01116635 ! neuron recognition GO:0008038 40 16 0,000 6,285E-03 0,01115824 ! mRNA splice site selection GO:0006376 44 16 0,000 6,285E-03 0,01115014 ! tissue regeneration GO:0042246 27 16 0,000 6,285E-03 0,01114204 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 6,285E-03 0,01113396 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 6,285E-03 0,0111259 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 6,285E-03 0,01111784 ! biomineral formation GO:0031214 22 16 0,000 6,285E-03 0,0111098 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 6,285E-03 0,01110176 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 6,285E-03 0,01109374 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 6,285E-03 0,01108573 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 6,285E-03 0,01107773 ! regulation of ATPase activity GO:0043462 26 16 0,000 6,285E-03 0,01106975 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 6,285E-03 0,01106177 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 6,285E-03 0,01105381 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 6,285E-03 0,01104585 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 6,285E-03 0,01103791 ! peptide hormone processing GO:0016486 27 16 0,000 6,285E-03 0,01102998 ! positive regulation of cell killing GO:0031343 36 17 0,000 6,676E-03 0,0117088 ! metencephalon development GO:0022037 32 17 0,000 6,676E-03 0,0117004 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 6,676E-03 0,01169202 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 6,676E-03 0,01168364 ! signal complex assembly GO:0007172 47 17 0,000 6,676E-03 0,01167528 ! filopodium assembly GO:0046847 42 17 0,000 6,676E-03 0,01166693 ! endothelial cell migration GO:0043542 31 17 0,000 6,676E-03 0,01165859 ! gene silencing by RNA GO:0031047 38 17 0,000 6,676E-03 0,01165026 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 6,676E-03 0,01164194 ! glial cell development GO:0021782 28 17 0,000 6,676E-03 0,01163364 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 6,676E-03 0,01162535 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 6,676E-03 0,01161707 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 6,676E-03 0,0116088 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 6,676E-03 0,01160054 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 6,676E-03 0,0115923 ! myoblast differentiation GO:0045445 50 17 0,000 6,676E-03 0,01158407 ! activation of MAPKK activity GO:0000186 43 17 0,000 6,676E-03 0,01157584 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 6,676E-03 0,01156763 ! regulation of survival gene product expression GO:0045884 38 17 0,000 6,676E-03 0,01155944 ! cardiac muscle tissue development GO:0048738 34 17 0,000 6,676E-03 0,01155125 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 6,676E-03 0,01154307 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 6,676E-03 0,01153491 ! complement activation, alternative pathway GO:0006957 19 17 0,000 6,676E-03 0,01152676 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 6,676E-03 0,01151862 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 6,676E-03 0,01151049 ! membrane budding GO:0006900 42 17 0,000 6,676E-03 0,01150237 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 6,676E-03 0,01149427 ! regulation of protein binding GO:0043393 33 17 0,000 6,676E-03 0,01148617 ! nucleobase metabolic process GO:0009112 43 17 0,000 6,676E-03 0,01147809 ! DNA unwinding during replication GO:0006268 26 17 0,000 6,676E-03 0,01147002 ! genitalia development GO:0048806 32 17 0,000 6,676E-03 0,01146196 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 6,676E-03 0,01145391 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 6,676E-03 0,01144587 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 6,676E-03 0,01143784 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 6,676E-03 0,01142983 ! neutrophil chemotaxis GO:0030593 29 17 0,000 6,676E-03 0,01142182 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 6,676E-03 0,01141383 ! steroid catabolic process GO:0006706 34 17 0,000 6,676E-03 0,01140585 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 6,676E-03 0,01139788 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 6,676E-03 0,01138992 ! gas transport GO:0015669 26 17 0,000 6,676E-03 0,01138197 ! organic cation transport GO:0015695 32 17 0,000 6,676E-03 0,01137403 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 6,676E-03 0,01136611 ! RNA 3'-end processing GO:0031123 37 17 0,000 6,676E-03 0,01135819 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 6,676E-03 0,01135029 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 7,068E-03 0,0120074 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 7,068E-03 0,01199906 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 7,068E-03 0,01199072 ! limbic system development GO:0021761 40 18 0,000 7,068E-03 0,0119824 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 7,068E-03 0,01197409 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 7,068E-03 0,01196579 ! adult walking behavior GO:0007628 36 18 0,000 7,068E-03 0,01195751 ! patterning of blood vessels GO:0001569 43 18 0,000 7,068E-03 0,01194923 ! heart looping GO:0001947 34 18 0,000 7,068E-03 0,01194097 ! ciliary or flagellar motility GO:0001539 32 18 0,000 7,068E-03 0,01193272 ! regulation of viral genome replication GO:0045069 30 18 0,000 7,068E-03 0,01192448 ! centrosome cycle GO:0007098 26 18 0,000 7,068E-03 0,01191625 ! positive regulation of proteolysis GO:0045862 36 18 0,000 7,068E-03 0,01190803 ! regulation of defense response to virus GO:0050688 35 18 0,000 7,068E-03 0,01189982 ! epidermis morphogenesis GO:0048730 43 18 0,000 7,068E-03 0,01189163 ! glycine metabolic process GO:0006544 30 18 0,000 7,068E-03 0,01188344 ! glutamine metabolic process GO:0006541 29 18 0,000 7,068E-03 0,01187527 ! response to retinoic acid GO:0032526 31 18 0,000 7,068E-03 0,01186711 ! cell-substrate junction assembly GO:0007044 56 18 0,000 7,068E-03 0,01185896 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 0,000 7,068E-03 0,01185082 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 7,068E-03 0,01184269 ! DNA integration GO:0015074 32 18 0,000 7,068E-03 0,01183457 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 7,068E-03 0,01182647 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 7,068E-03 0,01181837 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 7,068E-03 0,01181029 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 7,068E-03 0,01180222 ! neural crest cell migration GO:0001755 41 18 0,000 7,068E-03 0,01179415 ! long-chain fatty acid transport GO:0015909 32 18 0,000 7,068E-03 0,0117861 ! sphingolipid catabolic process GO:0030149 32 18 0,000 7,068E-03 0,01177806 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 7,068E-03 0,01177003 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 7,068E-03 0,01176202 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 7,068E-03 0,01175401 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 7,068E-03 0,01174601 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 7,068E-03 0,01173803 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 7,068E-03 0,01173005 ! detection of bacterium GO:0016045 22 18 0,000 7,068E-03 0,01172209 ! nerve development GO:0021675 34 18 0,000 7,068E-03 0,01171414 ! defense response to virus GO:0051607 43 18 0,000 7,068E-03 0,0117062 ! microspike assembly GO:0030035 46 18 0,000 7,068E-03 0,01169827 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 7,068E-03 0,01169035 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 7,068E-03 0,01168244 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 7,459E-03 0,01232087 ! positive regulation of translation GO:0045727 31 19 0,000 7,459E-03 0,01231255 ! negative regulation of defense response GO:0031348 27 19 0,000 7,459E-03 0,01230423 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 7,459E-03 0,01229593 ! neuron maturation GO:0042551 46 19 0,000 7,459E-03 0,01228764 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 7,459E-03 0,01227936 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 7,459E-03 0,01227109 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 7,459E-03 0,01226283 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 7,459E-03 0,01225459 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 7,459E-03 0,01224635 ! inositol metabolic process GO:0006020 33 19 0,000 7,459E-03 0,01223812 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 7,459E-03 0,01222991 ! memory GO:0007613 34 19 0,000 7,459E-03 0,01222171 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 7,459E-03 0,01221352 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 7,459E-03 0,01220534 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 7,459E-03 0,01219717 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 7,459E-03 0,01218901 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 7,459E-03 0,01218086 ! cerebral cortex development GO:0021987 40 19 0,000 7,459E-03 0,01217272 ! pigmentation during development GO:0048066 42 19 0,000 7,459E-03 0,0121646 ! response to vitamin A GO:0033189 32 19 0,000 7,459E-03 0,01215648 ! heme metabolic process GO:0042168 40 19 0,000 7,459E-03 0,01214838 ! neuromuscular junction development GO:0007528 43 19 0,000 7,459E-03 0,01214029 ! response to lipopolysaccharide GO:0032496 34 19 0,000 7,459E-03 0,0121322 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 7,459E-03 0,01212413 ! response to fungus GO:0009620 26 19 0,000 7,459E-03 0,01211607 ! peptide cross-linking GO:0018149 39 19 0,000 7,459E-03 0,01210802 ! protein export from nucleus GO:0006611 40 19 0,000 7,459E-03 0,01209998 ! heart process GO:0003015 32 19 0,000 7,459E-03 0,01209195 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 7,459E-03 0,01208393 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 7,459E-03 0,01207592 ! visual learning GO:0008542 38 19 0,000 7,459E-03 0,01206793 ! cellular pigmentation GO:0033059 37 19 0,000 7,459E-03 0,01205994 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 7,459E-03 0,01205196 ! peptide biosynthetic process GO:0043043 26 19 0,000 7,459E-03 0,012044 ! vitamin transport GO:0051180 31 19 0,000 7,459E-03 0,01203604 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 7,459E-03 0,0120281 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 7,459E-03 0,01202016 ! proximal/distal pattern formation GO:0009954 33 19 0,000 7,459E-03 0,01201224 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 7,459E-03 0,01200433 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 7,459E-03 0,01199642 ! cilium assembly GO:0042384 38 19 0,000 7,459E-03 0,01198853 ! peptide hormone secretion GO:0030072 32 19 0,000 7,459E-03 0,01198065 ! protein secretion GO:0009306 45 20 0,000 7,85E-03 0,01260062 ! protein import into nucleus, docking GO:0000059 42 20 0,000 7,85E-03 0,01259235 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 7,85E-03 0,01258408 ! positive regulation of ossification GO:0045778 50 20 0,000 7,85E-03 0,01257583 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 7,85E-03 0,01256759 ! skin development GO:0043588 42 20 0,000 7,85E-03 0,01255936 ! phosphoinositide phosphorylation GO:0046854 40 20 0,000 7,85E-03 0,01255114 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 7,85E-03 0,01254293 ! protein amino acid deacetylation GO:0006476 34 20 0,000 7,85E-03 0,01253474 ! protein amino acid acetylation GO:0006473 41 20 0,000 7,85E-03 0,01252655 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 0,000 7,85E-03 0,01251837 ! aminoglycan catabolic process GO:0006026 25 20 0,000 7,85E-03 0,01251021 ! response to vitamin GO:0033273 36 20 0,000 7,85E-03 0,01250205 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 7,85E-03 0,01249391 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 7,85E-03 0,01248577 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 7,85E-03 0,01247765 ! bile acid metabolic process GO:0008206 34 20 0,000 7,85E-03 0,01246954 ! response to alkaloid GO:0043279 38 20 0,000 7,85E-03 0,01246143 ! retinoid metabolic process GO:0001523 34 20 0,000 7,85E-03 0,01245334 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 7,85E-03 0,01244526 ! apoptotic mitochondrial changes GO:0008637 42 20 0,000 7,85E-03 0,01243719 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 7,85E-03 0,01242913 ! DNA duplex unwinding GO:0032508 30 20 0,000 7,85E-03 0,01242108 GO:0032392|DNA geometric change, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 7,85E-03 0,01241304 ! actin filament bundle formation GO:0051017 47 20 0,000 7,85E-03 0,01240501 ! body fluid secretion GO:0007589 33 20 0,000 7,85E-03 0,01239699 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 7,85E-03 0,01238898 ! peptide secretion GO:0002790 38 20 0,000 7,85E-03 0,01238098 ! behavioral interaction between organisms GO:0051705 47 20 0,000 7,85E-03 0,012373 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 7,85E-03 0,01236502 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 7,85E-03 0,01235705 ! protein localization in mitochondrion GO:0070585 39 20 0,000 7,85E-03 0,0123491 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 7,85E-03 0,01234115 ! cell-cell junction organization GO:0045216 43 20 0,000 7,85E-03 0,01233321 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 7,85E-03 0,01232529 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 7,85E-03 0,01231737 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 7,85E-03 0,01230946 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 7,85E-03 0,01230157 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 7,85E-03 0,01229368 ! regulation of glucose import GO:0046324 30 20 0,000 7,85E-03 0,01228581 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 7,85E-03 0,01227794 ! negative regulation of T cell activation GO:0050868 41 20 0,000 7,85E-03 0,01227009 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 7,85E-03 0,01226224 ! negative regulation of translation GO:0017148 32 20 0,000 7,85E-03 0,01225441 ! negative regulation of coagulation GO:0050819 30 20 0,000 7,85E-03 0,01224658 ! regulation of cell killing GO:0031341 46 21 0,000 8,241E-03 0,01284836 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 8,241E-03 0,01284016 ! hormone secretion GO:0046879 39 21 0,000 8,241E-03 0,01283198 ! lipid phosphorylation GO:0046834 43 21 0,000 8,241E-03 0,0128238 ! cAMP metabolic process GO:0046058 41 21 0,000 8,241E-03 0,01281564 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 8,241E-03 0,01280749 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 8,241E-03 0,01279935 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 8,241E-03 0,01279122 ! ovarian follicle development GO:0001541 39 21 0,000 8,241E-03 0,01278309 ! smooth muscle contraction GO:0006939 48 21 0,000 8,241E-03 0,01277498 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 0,000 8,241E-03 0,01276688 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 8,241E-03 0,01275879 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 8,241E-03 0,01275071 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 8,241E-03 0,01274264 ! plasma membrane fusion GO:0045026 33 21 0,000 8,241E-03 0,01273458 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 8,241E-03 0,01272653 ! prostaglandin metabolic process GO:0006693 43 21 0,000 8,241E-03 0,01271849 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 8,241E-03 0,01271046 ! sensory perception of pain GO:0019233 33 21 0,000 8,241E-03 0,01270244 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 8,241E-03 0,01269443 ! diencephalon development GO:0021536 36 21 0,000 8,241E-03 0,01268644 ! collagen fibril organization GO:0030199 62 21 0,000 8,241E-03 0,01267845 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 8,241E-03 0,01267047 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 8,241E-03 0,0126625 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 8,241E-03 0,01265454 ! vitamin A metabolic process GO:0006776 35 21 0,000 8,241E-03 0,01264659 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 8,241E-03 0,01263865 ! collagen catabolic process GO:0030574 29 21 0,000 8,241E-03 0,01263072 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 8,241E-03 0,0126228 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 8,241E-03 0,0126149 ! sperm-egg recognition GO:0035036 23 21 0,000 8,241E-03 0,012607 ! actin filament-based movement GO:0030048 47 21 0,000 8,241E-03 0,01259911 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 8,241E-03 0,01259123 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 8,632E-03 0,01318016 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 8,632E-03 0,01317192 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 8,632E-03 0,0131637 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 8,632E-03 0,01315549 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 8,632E-03 0,01314729 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 8,632E-03 0,0131391 ! microtubule-based transport GO:0010970 59 22 0,000 8,632E-03 0,01313092 ! hindlimb morphogenesis GO:0035137 47 22 0,000 8,632E-03 0,01312274 ! glutamate signaling pathway GO:0007215 48 22 0,000 8,632E-03 0,01311458 ! inactivation of MAPK activity GO:0000188 45 22 0,000 8,632E-03 0,01310643 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 8,632E-03 0,01309829 ! cellular response to starvation GO:0009267 37 22 0,000 8,632E-03 0,01309016 ! vacuolar transport GO:0007034 41 22 0,000 8,632E-03 0,01308204 ! central nervous system neuron development GO:0021954 47 22 0,000 8,632E-03 0,01307393 ! fucose metabolic process GO:0006004 44 22 0,000 8,632E-03 0,01306583 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 8,632E-03 0,01305774 ! D-ribose metabolic process GO:0006014 36 22 0,000 8,632E-03 0,01304966 ! apoptotic nuclear changes GO:0030262 34 22 0,000 8,632E-03 0,01304159 ! ureteric bud development GO:0001657 50 22 0,000 8,632E-03 0,01303353 ! cell aging GO:0007569 48 22 0,000 8,632E-03 0,01302548 ! stem cell differentiation GO:0048863 57 22 0,000 8,632E-03 0,01301744 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 8,632E-03 0,01300941 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 8,632E-03 0,01300139 ! cytolysis GO:0019835 27 22 0,000 8,632E-03 0,01299338 ! renal system process GO:0003014 42 22 0,000 8,632E-03 0,01298538 ! vasodilation GO:0042311 40 22 0,000 8,632E-03 0,01297739 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 8,632E-03 0,0129694 ! positive regulation of locomotion GO:0040017 44 22 0,000 8,632E-03 0,01296143 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 8,632E-03 0,01295347 ! detection of chemical stimulus GO:0009593 42 22 0,000 8,632E-03 0,01294552 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 8,632E-03 0,01293758 ! positive regulation of intracellular transport GO:0032388 42 22 0,000 8,632E-03 0,01292965 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 8,632E-03 0,01292172 ! peptidyl-serine modification GO:0018209 50 22 0,000 8,632E-03 0,01291381 ! regulation of cytokine secretion GO:0050707 41 22 0,000 8,632E-03 0,01290591 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 8,632E-03 0,01289801 ! sarcomere organization GO:0045214 32 22 0,000 8,632E-03 0,01289013 ! positive regulation of B cell activation GO:0050871 42 22 0,000 8,632E-03 0,01288225 ! response to cytokine stimulus GO:0034097 69 22 0,000 8,632E-03 0,01287439 ! activation of JUN kinase activity GO:0007257 47 22 0,000 8,632E-03 0,01286654 ! terpenoid metabolic process GO:0006721 40 22 0,000 8,632E-03 0,01285869 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 8,632E-03 0,01285085 ! gut development GO:0048565 44 22 0,000 8,632E-03 0,01284303 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 8,632E-03 0,01283521 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 8,632E-03 0,0128274 ! protein stabilization GO:0050821 41 22 0,000 8,632E-03 0,01281961 ! positive regulation of DNA replication GO:0045740 44 23 0,000 9,023E-03 0,01339173 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 9,023E-03 0,01338359 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 9,023E-03 0,01337547 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 9,023E-03 0,01336736 ! gluconeogenesis GO:0006094 38 23 0,000 9,023E-03 0,01335926 ! glycerol metabolic process GO:0006071 40 23 0,000 9,023E-03 0,01335117 ! viral genome replication GO:0019079 44 23 0,000 9,023E-03 0,01334309 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 9,023E-03 0,01333501 ! glucosamine metabolic process GO:0006041 31 23 0,000 9,023E-03 0,01332695 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 9,023E-03 0,0133189 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 9,023E-03 0,01331086 ! regeneration GO:0031099 42 23 0,000 9,023E-03 0,01330282 ! axis specification GO:0009798 43 23 0,000 9,023E-03 0,0132948 ! visual behavior GO:0007632 46 23 0,000 9,023E-03 0,01328679 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 9,023E-03 0,01327878 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 9,023E-03 0,01327079 ! response to ethanol GO:0045471 47 23 0,000 9,023E-03 0,0132628 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 9,023E-03 0,01325483 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 9,023E-03 0,01324686 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 9,023E-03 0,01323891 ! peroxisome organization GO:0007031 43 23 0,000 9,023E-03 0,01323096 ! lysosome organization GO:0007040 47 23 0,000 9,023E-03 0,01322302 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 9,023E-03 0,0132151 ! vesicle targeting GO:0006903 49 23 0,000 9,023E-03 0,01320718 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 9,023E-03 0,01319927 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 9,023E-03 0,01319137 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 9,023E-03 0,01318348 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 9,023E-03 0,0131756 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 9,023E-03 0,01316773 ! DNA modification GO:0006304 36 23 0,000 9,023E-03 0,01315987 ! fatty acid transport GO:0015908 47 23 0,000 9,023E-03 0,01315202 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 9,023E-03 0,01314417 ! regulation of bone mineralization GO:0030500 54 23 0,000 9,023E-03 0,01313634 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 9,023E-03 0,01312852 ! hormone transport GO:0009914 41 23 0,000 9,023E-03 0,0131207 ! cell-cell recognition GO:0009988 28 23 0,000 9,023E-03 0,0131129 ! negative regulation of cytokine production GO:0001818 41 23 0,000 9,023E-03 0,0131051 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 9,023E-03 0,01309731 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 9,023E-03 0,01308954 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 9,413E-03 0,01364805 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 9,413E-03 0,01363995 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 9,413E-03 0,01363187 ! regulation of cellular catabolic process GO:0031329 55 24 0,000 9,413E-03 0,01362379 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 9,413E-03 0,01361572 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 9,413E-03 0,01360767 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 9,413E-03 0,01359962 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 9,413E-03 0,01359158 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 9,413E-03 0,01358356 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 9,413E-03 0,01357554 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 9,413E-03 0,01356753 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 0,000 9,413E-03 0,01355953 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 9,413E-03 0,01355154 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 9,413E-03 0,01354356 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 9,413E-03 0,01353558 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 9,413E-03 0,01352762 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 9,413E-03 0,01351967 ! barbed-end actin filament capping GO:0051016 58 24 0,000 9,413E-03 0,01351173 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 9,413E-03 0,01350379 ! regulation of viral reproduction GO:0050792 41 24 0,000 9,413E-03 0,01349587 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 9,413E-03 0,01348795 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 52 24 0,000 9,413E-03 0,01348005 ! leukotriene metabolic process GO:0006691 47 24 0,000 9,413E-03 0,01347215 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 9,413E-03 0,01346426 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 9,413E-03 0,01345638 ! membrane depolarization GO:0051899 45 24 0,000 9,413E-03 0,01344851 ! pallium development GO:0021543 56 24 0,000 9,413E-03 0,01344065 ! oogenesis GO:0048477 44 24 0,000 9,413E-03 0,0134328 ! synaptic vesicle transport GO:0048489 52 24 0,000 9,413E-03 0,01342496 ! detection of biotic stimulus GO:0009595 34 24 0,000 9,413E-03 0,01341713 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 9,413E-03 0,01340931 ! platelet activation GO:0030168 41 24 0,000 9,413E-03 0,01340149 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 9,413E-03 0,01339369 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 9,413E-03 0,01338589 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 9,413E-03 0,0133781 ! porphyrin metabolic process GO:0006778 50 24 0,000 9,413E-03 0,01337032 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 9,413E-03 0,01336256 ! negative regulation of catabolic process GO:0009895 52 24 0,000 9,413E-03 0,0133548 ! regulation of amine transport GO:0051952 41 24 0,000 9,413E-03 0,01334705 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 9,413E-03 0,0133393 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 9,804E-03 0,01388452 ! positive regulation of fibroblast proliferation GO:0048146 48 25 0,000 9,804E-03 0,01387647 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 9,804E-03 0,01386844 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 0,000 9,804E-03 0,01386041 ! regulation of transmembrane transport GO:0034762 39 25 0,000 9,804E-03 0,01385239 ! leukocyte adhesion GO:0007159 55 25 0,000 9,804E-03 0,01384439 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 9,804E-03 0,01383639 ! phototransduction GO:0007602 37 25 0,000 9,804E-03 0,0138284 ! keratinization GO:0031424 37 25 0,000 9,804E-03 0,01382042 ! vasculogenesis GO:0001570 49 25 0,000 9,804E-03 0,01381245 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 9,804E-03 0,01380449 ! vacuole organization GO:0007033 49 25 0,000 9,804E-03 0,01379654 ! polysaccharide catabolic process GO:0000272 30 25 0,000 9,804E-03 0,01378859 ! negative regulation of DNA replication GO:0008156 45 25 0,000 9,804E-03 0,01378066 ! receptor metabolic process GO:0043112 53 25 0,000 9,804E-03 0,01377274 ! chromosome condensation GO:0030261 48 25 0,000 9,804E-03 0,01376482 ! regulation of insulin secretion GO:0050796 42 25 0,000 9,804E-03 0,01375691 ! regulation of behavior GO:0050795 48 25 0,000 9,804E-03 0,01374902 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 9,804E-03 0,01374113 ! interaction with host GO:0051701 66 25 0,000 9,804E-03 0,01373325 ! lymphocyte proliferation GO:0046651 55 25 0,000 9,804E-03 0,01372538 ! regulation of biomineral formation GO:0070167 56 25 0,000 9,804E-03 0,01371752 ! immunoglobulin production GO:0002377 62 25 0,000 9,804E-03 0,01370967 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 9,804E-03 0,01370182 ! leukocyte homeostasis GO:0001776 50 25 0,000 9,804E-03 0,01369399 ! cellular alkene metabolic process GO:0043449 48 25 0,000 9,804E-03 0,01368617 ! liver development GO:0001889 55 25 0,000 9,804E-03 0,01367835 ! protein tetramerization GO:0051262 57 25 0,000 9,804E-03 0,01367054 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,01019413 0,01420666 ! myelination GO:0042552 50 26 0,000 0,01019413 0,01419856 ! initiation of viral infection GO:0019059 60 26 0,000 0,01019413 0,01419047 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,01019413 0,01418239 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,01019413 0,01417431 ! molting cycle process GO:0022404 52 26 0,000 0,01019413 0,01416625 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,01019413 0,0141582 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,01019413 0,01415015 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,01019413 0,01414212 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,01019413 0,01413409 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,01019413 0,01412607 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,01019413 0,01411807 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,01019413 0,01411007 ! digestive system process GO:0022600 49 26 0,000 0,01019413 0,01410208 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,01019413 0,0140941 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,01019413 0,01408613 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 0,000 0,01019413 0,01407816 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,01019413 0,01407021 ! osteoblast differentiation GO:0001649 63 26 0,000 0,01019413 0,01406226 ! neural crest cell development GO:0014032 59 26 0,000 0,01019413 0,01405433 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,01019413 0,0140464 ! negative regulation of cell development GO:0010721 83 26 0,000 0,01019413 0,01403848 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,01019413 0,01403057 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,01019413 0,01402267 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,01019413 0,01401478 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,01019413 0,0140069 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,01019413 0,01399903 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,01019413 0,01399116 ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,01019413 0,01398331 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,01019413 0,01397546 ! blastocyst development GO:0001824 50 26 0,000 0,01019413 0,01396762 ! telomere organization GO:0032200 46 26 0,000 0,01019413 0,01395979 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,01019413 0,01395197 ! neural tube closure GO:0001843 58 26 0,000 0,01019413 0,01394416 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,01019413 0,01393636 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,01019413 0,01392856 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,01019413 0,01392078 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,01058428 0,01444548 ! embryonic pattern specification GO:0009880 49 27 0,000 0,01058428 0,01443741 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,01058428 0,01442935 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,01058428 0,01442131 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,01058428 0,01441327 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,01058428 0,01440524 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,01058428 0,01439722 ! iron ion transport GO:0006826 65 27 0,000 0,01058428 0,01438921 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,01058428 0,0143812 ! superoxide metabolic process GO:0006801 41 27 0,000 0,01058428 0,01437321 ! tube lumen formation GO:0035148 59 27 0,000 0,01058428 0,01436522 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,01058428 0,01435725 ! insulin receptor signaling pathway GO:0008286 66 27 0,000 0,01058428 0,01434928 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,01058428 0,01434132 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,01058428 0,01433337 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,01058428 0,01432543 ! response to starvation GO:0042594 47 27 0,000 0,01058428 0,0143175 ! response to toxin GO:0009636 49 27 0,000 0,01058428 0,01430957 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,01058428 0,01430166 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,01058428 0,01429375 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,01058428 0,01428586 ! leukocyte proliferation GO:0070661 59 27 0,000 0,01058428 0,01427797 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,01058428 0,01427009 ! regulation of fibroblast proliferation GO:0048145 56 28 0,000 0,01097429 0,01478775 ! neuron fate commitment GO:0048663 52 28 0,000 0,01097429 0,01477959 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 0,000 0,01097429 0,01477145 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,01097429 0,01476332 ! protein amino acid acylation GO:0043543 59 28 0,000 0,01097429 0,01475519 ! vesicle docking GO:0048278 55 28 0,000 0,01097429 0,01474708 ! circadian rhythm GO:0007623 56 28 0,000 0,01097429 0,01473897 ! dendrite development GO:0016358 67 28 0,000 0,01097429 0,01473087 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,01097429 0,01472278 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,01097429 0,0147147 ! sperm motility GO:0030317 37 28 0,000 0,01097429 0,01470663 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,01097429 0,01469857 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,01097429 0,01469051 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,01097429 0,01468247 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,01097429 0,01467443 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,01097429 0,0146664 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,01097429 0,01465838 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,01097429 0,01465037 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,01097429 0,01464237 ! glutathione metabolic process GO:0006749 42 28 0,000 0,01097429 0,01463438 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,01097429 0,0146264 ! lipid oxidation GO:0034440 48 28 0,000 0,01097429 0,01461842 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,01097429 0,01461045 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,01097429 0,0146025 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,01136415 0,01511302 ! translational initiation GO:0006413 66 29 0,000 0,01136415 0,0151048 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,01136415 0,01509658 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,01136415 0,01508838 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,01136415 0,01508018 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,01136415 0,015072 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,01136415 0,01506382 ! primary neural tube formation GO:0014020 61 29 0,000 0,01136415 0,01505565 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,01136415 0,01504749 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,01136415 0,01503934 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,01136415 0,0150312 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,01136415 0,01502306 ! somitogenesis GO:0001756 52 29 0,000 0,01136415 0,01501494 ! synaptogenesis GO:0007416 46 29 0,000 0,01136415 0,01500682 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,01136415 0,01499871 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,01136415 0,01499062 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,01136415 0,01498253 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,01136415 0,01497444 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,01175387 0,01547963 ! phenol metabolic process GO:0018958 56 30 0,000 0,01175387 0,01547128 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,01175387 0,01546295 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,01175387 0,01545463 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,01175387 0,01544632 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,01175387 0,01543801 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,01175387 0,01542972 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,01175387 0,01542143 ! acute-phase response GO:0006953 50 30 0,000 0,01175387 0,01541315 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,01175387 0,01540488 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,01175387 0,01539662 ! myofibril assembly GO:0030239 50 30 0,000 0,01175387 0,01538837 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,01175387 0,01538013 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,01175387 0,0153719 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,01175387 0,01536367 ! cell fate determination GO:0001709 64 30 0,000 0,01175387 0,01535546 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,01175387 0,01534725 ! phospholipid transport GO:0015914 65 30 0,000 0,01175387 0,01533905 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,01175387 0,01533086 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,01175387 0,01532268 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,01175387 0,01531451 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,01175387 0,01530635 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,01175387 0,01529819 GO:0048871|multicellular organismal homeostasis, ! regulation of B cell activation GO:0050864 55 30 0,000 0,01175387 0,01529005 ! regulation of coagulation GO:0050818 52 30 0,000 0,01175387 0,01528191 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,01214345 0,01578002 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,01214345 0,01577163 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,01214345 0,01576325 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,01214345 0,01575488 ! cell junction assembly GO:0034329 85 31 0,000 0,01214345 0,01574652 ! regulation of innate immune response GO:0045088 57 31 0,000 0,01214345 0,01573817 ! ovulation cycle process GO:0022602 55 31 0,000 0,01214345 0,01572982 ! peptide transport GO:0015833 60 31 0,000 0,01214345 0,01572148 ! male gonad development GO:0008584 56 31 0,000 0,01214345 0,01571316 ! iron ion homeostasis GO:0055072 60 31 0,000 0,01214345 0,01570484 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,01214345 0,01569653 ! detection of light stimulus GO:0009583 44 31 0,000 0,01214345 0,01568823 ! cellular response to extracellular stimulus GO:0031668 52 31 0,000 0,01214345 0,01567994 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,01214345 0,01567165 ! natural killer cell activation GO:0030101 50 31 0,000 0,01214345 0,01566338 ! ensheathment of neurons GO:0007272 64 31 0,000 0,01214345 0,01565511 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,01214345 0,01564686 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,01214345 0,01563861 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,01214345 0,01563037 ! eye morphogenesis GO:0048592 65 31 0,000 0,01214345 0,01562214 ! response to heat GO:0009408 54 31 0,000 0,01214345 0,01561392 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,01214345 0,0156057 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,01253288 0,0160977 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,01253288 0,01608924 ! collagen metabolic process GO:0032963 49 32 0,000 0,01253288 0,01608079 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,01253288 0,01607235 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,01253288 0,01606392 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,01253288 0,0160555 ! metanephros development GO:0001656 81 32 0,000 0,01253288 0,01604708 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,01253288 0,01603868 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,01253288 0,01603028 ! muscle cell development GO:0055001 52 32 0,000 0,01253288 0,01602189 ! mesoderm formation GO:0001707 73 32 0,000 0,01253288 0,01601351 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,01253288 0,01600514 ! ovulation cycle GO:0042698 57 32 0,000 0,01253288 0,01599678 ! peripheral nervous system development GO:0007422 68 32 0,000 0,01253288 0,01598842 ! BMP signaling pathway GO:0030509 71 32 0,000 0,01253288 0,01598008 ! hindbrain development GO:0030902 65 32 0,000 0,01253288 0,01597174 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,01253288 0,01596342 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,01253288 0,0159551 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,01253288 0,01594679 ! gene silencing GO:0016458 71 32 0,000 0,01253288 0,01593849 ! regulation of pH GO:0006885 56 33 0,000 0,01292217 0,01642501 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,01292217 0,01641647 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,01292217 0,01640794 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,01292217 0,01639941 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,01292217 0,0163909 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,01292217 0,01638239 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,01292217 0,0163739 ! response to ionizing radiation GO:0010212 74 33 0,000 0,01292217 0,01636541 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,01292217 0,01635693 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,01292217 0,01634846 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,01292217 0,01634 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,01292217 0,01633154 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,01292217 0,0163231 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,01292217 0,01631466 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,01292217 0,01630624 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,01331132 0,01678862 ! glial cell differentiation GO:0010001 67 34 0,000 0,01331132 0,01677996 ! post-embryonic development GO:0009791 76 34 0,000 0,01331132 0,01677131 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,01331132 0,01676266 ! cholesterol transport GO:0030301 62 34 0,000 0,01331132 0,01675403 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,01331132 0,0167454 ! spliceosome assembly GO:0000245 75 34 0,000 0,01331132 0,01673678 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,01331132 0,01672817 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,01331132 0,01671957 ! formation of primary germ layer GO:0001704 76 34 0,000 0,01331132 0,01671098 ! cell fate specification GO:0001708 56 34 0,000 0,01331132 0,0167024 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,01331132 0,01669382 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,01331132 0,01668526 ! adult locomotory behavior GO:0008344 62 34 0,000 0,01331132 0,0166767 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,01331132 0,01666815 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,01370033 0,01714647 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,01370033 0,01713769 ! negative regulation of secretion GO:0051048 68 35 0,000 0,01370033 0,01712892 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,01370033 0,01712016 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,01370033 0,0171114 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,01370033 0,01710266 ! membrane docking GO:0022406 69 35 0,000 0,01370033 0,01709393 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,01370033 0,0170852 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,01370033 0,01707648 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,01370033 0,01706778 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,01370033 0,01705908 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,01370033 0,01705039 ! ceramide metabolic process GO:0006672 72 35 0,000 0,01370033 0,0170417 ! telencephalon development GO:0021537 81 35 0,000 0,01370033 0,01703303 ! sterol transport GO:0015918 63 35 0,000 0,01370033 0,01702437 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,01370033 0,01701571 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,01370033 0,01700707 ! placenta development GO:0001890 53 35 0,000 0,01370033 0,01699843 ! vesicle localization GO:0051648 70 35 0,000 0,01370033 0,0169898 ! regulation of muscle development GO:0048634 82 36 0,000 0,0140892 0,01746317 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,0140892 0,01745431 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,0140892 0,01744547 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,0140892 0,01743663 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,0140892 0,0174278 ! positive regulation of cell development GO:0010720 85 36 0,000 0,0140892 0,01741898 ! protein targeting to membrane GO:0006612 75 36 0,000 0,0140892 0,01741017 ! regulation of proteolysis GO:0030162 77 36 0,000 0,0140892 0,01740137 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,0140892 0,01739257 ! aerobic respiration GO:0009060 56 36 0,000 0,0140892 0,01738379 ! cytokine production GO:0001816 68 36 0,000 0,0140892 0,01737501 ! embryonic organ development GO:0048568 67 36 0,000 0,0140892 0,01736625 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,0140892 0,01735749 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,0140892 0,01734874 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,01447792 0,01781841 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,01447792 0,01780944 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,01447792 0,01780048 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,01447792 0,01779153 ! odontogenesis GO:0042476 74 37 0,000 0,01447792 0,01778258 ! actomyosin structure organization GO:0031032 68 37 0,000 0,01447792 0,01777364 ! cell junction organization GO:0034330 96 37 0,000 0,01447792 0,01776472 ! tissue remodeling GO:0048771 78 37 0,000 0,01447792 0,0177558 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,01447792 0,01774689 ! female gonad development GO:0008585 71 37 0,000 0,01447792 0,01773799 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,01447792 0,0177291 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,01447792 0,01772022 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,01447792 0,01771134 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,01447792 0,01770248 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,0148665 0,01816851 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,0148665 0,01815943 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,0148665 0,01815035 ! organic anion transport GO:0015711 82 38 0,000 0,0148665 0,01814129 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,0148665 0,01813223 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,0148665 0,01812318 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,0148665 0,01811414 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,0148665 0,01810511 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,0148665 0,01809609 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,0148665 0,01808708 ! regulation of protein stability GO:0031647 77 38 0,000 0,0148665 0,01807808 ! spermatid development GO:0007286 69 38 0,000 0,0148665 0,01806908 ! glycogen metabolic process GO:0005977 63 38 0,000 0,0148665 0,0180601 ! pigment metabolic process GO:0042440 87 38 0,000 0,0148665 0,01805112 ! cellular response to insulin stimulus GO:0032869 85 38 0,000 0,0148665 0,01804215 ! neural tube formation GO:0001841 79 38 0,000 0,0148665 0,01803319 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,01525494 0,01849519 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,01525494 0,01848602 ! negative regulation of binding GO:0051100 71 39 0,000 0,01525494 0,01847685 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,01525494 0,01846769 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,01525494 0,01845855 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,01525494 0,01844941 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,01525494 0,01844028 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,01525494 0,01843116 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,01525494 0,01842205 ! positive regulation of leukocyte proliferation GO:0070665 70 39 0,000 0,01525494 0,01841295 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,01525494 0,01840386 ! glucan metabolic process GO:0044042 64 39 0,000 0,01525494 0,01839477 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,01564323 0,01885368 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 0,000 0,01564323 0,01884439 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,01564323 0,0188351 ! learning GO:0007612 82 40 0,000 0,01564323 0,01882582 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,01564323 0,01881655 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,01564323 0,01880729 ! lipid homeostasis GO:0055088 75 40 0,000 0,01564323 0,01879804 ! mismatch repair GO:0006298 58 40 0,000 0,01564323 0,0187888 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,01564323 0,01877956 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,01564323 0,01877034 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,01564323 0,01876113 ! RNA export from nucleus GO:0006405 61 41 0,000 0,01603138 0,01921721 ! mRNA catabolic process GO:0006402 79 41 0,000 0,01603138 0,01920778 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,01603138 0,01919837 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,01603138 0,01918896 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,01603138 0,01917956 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,01603138 0,01917018 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,01603138 0,0191608 ! gliogenesis GO:0042063 91 41 0,000 0,01603138 0,01915143 ! feeding behavior GO:0007631 69 41 0,000 0,01603138 0,01914207 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,01603138 0,01913272 ! mesenchymal cell development GO:0014031 94 41 0,000 0,01603138 0,01912337 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,01603138 0,01911404 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,01603138 0,01910472 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,01603138 0,0190954 ! spermatid differentiation GO:0048515 73 41 0,000 0,01603138 0,0190861 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,01603138 0,0190768 ! RNA modification GO:0009451 64 41 0,000 0,01603138 0,01906751 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,0164194 0,0195195 ! ear morphogenesis GO:0042471 64 42 0,000 0,0164194 0,01951001 ! organic ether metabolic process GO:0018904 59 42 0,000 0,0164194 0,01950053 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,0164194 0,01949105 ! regulation of intracellular protein transport GO:0033157 86 42 0,000 0,0164194 0,01948158 ! T cell differentiation GO:0030217 93 42 0,000 0,0164194 0,01947213 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,0164194 0,01946268 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,0164194 0,01945324 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,0164194 0,01944381 ! regulation of protein secretion GO:0050708 77 42 0,000 0,0164194 0,01943439 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,0164194 0,01942498 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,0164194 0,01941558 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,01680726 0,01986461 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 0,000 0,01680726 0,019855 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,01680726 0,01984541 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,01680726 0,01983582 ! regulation of tube size GO:0035150 76 43 0,000 0,01680726 0,01982624 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,01680726 0,01981667 ! glucose transport GO:0015758 66 43 0,000 0,01680726 0,01980711 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,01680726 0,01979756 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,01680726 0,01978802 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,01680726 0,01977849 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,01680726 0,01976897 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,01680726 0,01975945 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,01680726 0,01974995 ! segmentation GO:0035282 78 43 0,000 0,01680726 0,01974046 ! ion transmembrane transport GO:0034220 79 43 0,000 0,01680726 0,01973097 ! neuron migration GO:0001764 85 43 0,000 0,01680726 0,01972149 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,01680726 0,01971202 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,01719499 0,02015708 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,01719499 0,02014742 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,01719499 0,02013776 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,01719499 0,02012811 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,01719499 0,02011847 ! hexose transport GO:0008645 68 44 0,000 0,01719499 0,02010884 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,01719499 0,02009922 ! striated muscle contraction GO:0006941 85 44 0,000 0,01719499 0,02008961 ! phagocytosis GO:0006909 105 44 0,000 0,01719499 0,02008 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,01719499 0,02007041 ! double-strand break repair GO:0006302 85 44 0,000 0,01719499 0,02006082 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,01758258 0,02050321 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,01758258 0,02049343 ! regulation of epithelial cell proliferation GO:0050678 122 45 0,000 0,01758258 0,02048366 ! induction of apoptosis by intracellular signals GO:0008629 95 45 0,000 0,01758258 0,0204739 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,01758258 0,02046414 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,01758258 0,0204544 ! biopolymer methylation GO:0043414 91 45 0,000 0,01758258 0,02044466 ! B cell differentiation GO:0030183 124 45 0,000 0,01758258 0,02043494 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,01758258 0,02042522 ! female gamete generation GO:0007292 71 45 0,000 0,01758258 0,02041551 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,01758258 0,02040581 ! polyol metabolic process GO:0019751 77 45 0,000 0,01758258 0,02039612 ! developmental growth GO:0048589 88 45 0,000 0,01758258 0,02038644 ! maintenance of location in cell GO:0051651 101 45 0,000 0,01758258 0,02037677 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,01797002 0,02081591 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,01797002 0,02080605 ! glycolysis GO:0006096 71 46 0,000 0,01797002 0,02079619 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 0,000 0,01797002 0,02078634 ! regulation of gene-specific transcription GO:0032583 102 46 0,000 0,01797002 0,02077651 ! leukocyte migration GO:0050900 75 46 0,000 0,01797002 0,02076668 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,01797002 0,02075686 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,01797002 0,02074705 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,01797002 0,02073725 ! pigmentation GO:0043473 103 46 0,000 0,01797002 0,02072746 ! cell growth GO:0016049 90 46 0,000 0,01797002 0,02071768 ! positive regulation of protein transport GO:0051222 80 46 0,000 0,01797002 0,0207079 ! neural tube development GO:0021915 91 47 0,000 0,01835732 0,02114424 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,01835732 0,02113428 ! response to insulin stimulus GO:0032868 98 47 0,000 0,01835732 0,02112432 ! positive regulation of defense response GO:0031349 88 48 0,000 0,01874448 0,02155968 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,01874448 0,02154954 ! mitochondrial transport GO:0006839 94 48 0,000 0,01874448 0,0215394 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,01874448 0,02152927 ! cellular component disassembly GO:0022411 89 48 0,000 0,01874448 0,02151916 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,01874448 0,02150905 ! endosome transport GO:0016197 127 48 0,000 0,01874448 0,02149895 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,01874448 0,02148886 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,01874448 0,02147878 ! male sex differentiation GO:0046661 93 48 0,000 0,01874448 0,02146871 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,01874448 0,02145865 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,01874448 0,0214486 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,01874448 0,02143856 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,01874448 0,02142853 ! methylation GO:0032259 97 48 0,000 0,01874448 0,02141851 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,0191315 0,02185051 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,0191315 0,0218403 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,0191315 0,0218301 ! JNK cascade GO:0007254 106 49 0,000 0,0191315 0,02181991 ! regulation of mast cell proliferation GO:0070666 89 49 0,000 0,0191315 0,02180973 ! protein homooligomerization GO:0051260 84 49 0,000 0,0191315 0,02179956 ! regulation of action potential GO:0001508 102 50 0,000 0,01951837 0,02223002 ! regulation of ion transport GO:0043269 86 50 0,000 0,01951837 0,02221966 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,01951837 0,02220931 ! endocrine system development GO:0035270 109 50 0,000 0,01951837 0,02219897 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,01951837 0,02218864 ! activation of caspase activity GO:0006919 95 50 0,000 0,01951837 0,02217832 ! regulation of ossification GO:0030278 123 50 0,000 0,01951837 0,02216801 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,01951837 0,02215771 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,01951837 0,02214742 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,01951837 0,02213713 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,01951837 0,02212686 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,01951837 0,0221166 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,01990511 0,02254436 ! viral infectious cycle GO:0019058 104 51 0,000 0,01990511 0,02253391 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,01990511 0,02252347 ! peptide metabolic process GO:0006518 80 51 0,000 0,01990511 0,02251305 ! response to temperature stimulus GO:0009266 84 51 0,000 0,01990511 0,02250263 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,01990511 0,02249222 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,01990511 0,02248182 ! positive regulation of binding GO:0051099 88 52 0,000 0,0202917 0,02290787 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,0202917 0,02289729 ! Notch signaling pathway GO:0007219 111 52 0,000 0,0202917 0,02288671 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,0202917 0,02287615 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,0202917 0,0228656 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,0202917 0,02285506 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,0202917 0,02284453 ! excretion GO:0007588 87 52 0,000 0,0202917 0,022834 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,0202917 0,02282349 ! histone modification GO:0016570 104 52 0,000 0,0202917 0,02281299 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,0202917 0,0228025 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,0202917 0,02279201 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,0202917 0,02278154 ! amino acid activation GO:0043038 98 52 0,000 0,0202917 0,02277107 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,02067815 0,02319409 ! positive regulation of growth GO:0045927 96 53 0,000 0,02067815 0,02318344 ! inner ear development GO:0048839 89 53 0,000 0,02067815 0,02317281 ! chromatin remodeling GO:0006338 122 53 0,000 0,02067815 0,02316218 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,02067815 0,02315157 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,02067815 0,02314096 ! vesicle organization GO:0016050 127 53 0,000 0,02067815 0,02313037 ! regulation of leukocyte proliferation GO:0070663 97 53 0,000 0,02067815 0,02311978 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,02067815 0,02310921 ! cartilage development GO:0051216 99 53 0,000 0,02067815 0,02309864 ! synapse organization GO:0050808 102 53 0,000 0,02067815 0,02308808 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,02106446 0,02350867 ! regulation of translational initiation GO:0006446 87 54 0,000 0,02106446 0,02349794 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,02106446 0,02348721 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,02106446 0,0234765 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 0,000 0,02106446 0,02346579 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,02106446 0,02345509 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,02106446 0,02344441 ! membrane fusion GO:0006944 122 54 0,000 0,02106446 0,02343373 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,02106446 0,02342307 ! covalent chromatin modification GO:0016569 115 54 0,000 0,02106446 0,02341241 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,02106446 0,02340176 ! regulation of cell shape GO:0008360 142 54 0,000 0,02106446 0,02339113 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,02106446 0,0233805 ! RNA catabolic process GO:0006401 103 55 0,000 0,02145063 0,02379831 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,02145063 0,02378751 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,02145063 0,02377672 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,02145063 0,02376593 ! cell recognition GO:0008037 98 55 0,000 0,02145063 0,02375516 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,02145063 0,0237444 ! cell maturation GO:0048469 107 55 0,000 0,02145063 0,02373364 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,02145063 0,0237229 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,02145063 0,02371217 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,02183666 0,02412797 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,02183666 0,02411707 ! glucose catabolic process GO:0006007 88 56 0,000 0,02183666 0,02410617 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,02183666 0,02409528 ! RNA elongation GO:0006354 90 56 0,000 0,02183666 0,0240844 ! chloride transport GO:0006821 102 57 0,000 0,02222254 0,02449895 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,02222254 0,0244879 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,02222254 0,02447686 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 131 57 0,000 0,02222254 0,02446582 ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,02222254 0,0244548 ! heart morphogenesis GO:0003007 105 57 0,000 0,02222254 0,02444379 ! regulation of intracellular transport GO:0032386 108 57 0,000 0,02222254 0,02443279 ! regulation of actin filament length GO:0030832 118 58 0,000 0,02260828 0,02484572 ! positive regulation of cell migration GO:0030335 137 58 0,000 0,02260828 0,02483455 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,02260828 0,02482339 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,02260828 0,02481224 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,02260828 0,02480109 ! aging GO:0007568 112 58 0,000 0,02260828 0,02478996 ! gastrulation GO:0007369 122 58 0,000 0,02260828 0,02477884 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,02260828 0,02476773 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,02260828 0,02475663 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,02260828 0,02474554 ! maintenance of location GO:0051235 124 58 0,000 0,02260828 0,02473445 ! nuclear export GO:0051168 110 59 0,000 0,02299389 0,02514506 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,02337935 0,02555514 ! lipid modification GO:0030258 112 60 0,000 0,02337935 0,02554371 ! DNA catabolic process GO:0006308 94 60 0,000 0,02337935 0,0255323 ! regulation of endocytosis GO:0030100 104 60 0,000 0,02337935 0,02552089 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,02337935 0,02550949 ! adult behavior GO:0030534 104 60 0,000 0,02337935 0,0254981 ! kidney development GO:0001822 133 60 0,000 0,02337935 0,02548672 ! positive regulation of secretion GO:0051047 110 61 0,000 0,02376467 0,02589522 ! regulation of cellular component size GO:0032535 125 61 0,000 0,02376467 0,02588367 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,02376467 0,02587214 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,02376467 0,02586062 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,02376467 0,0258491 ! regulation of heart contraction GO:0008016 123 61 0,000 0,02376467 0,0258376 ! camera-type eye development GO:0043010 126 61 0,000 0,02376467 0,0258261 ! proton transport GO:0015992 117 61 0,000 0,02376467 0,02581462 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,02376467 0,02580315 ! viral reproductive process GO:0022415 132 62 0,000 0,02414985 0,02620972 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,02414985 0,02619808 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,02414985 0,02618645 ! tRNA processing GO:0008033 102 62 0,000 0,02414985 0,02617483 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,02414985 0,02616323 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,02453488 0,02656858 ! mesoderm development GO:0007498 128 63 0,000 0,02453488 0,02655681 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,02453488 0,02654505 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,02453488 0,0265333 ! hydrogen transport GO:0006818 121 64 0,000 0,02491978 0,02693762 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,02491978 0,02692571 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,02491978 0,0269138 ! protein amino acid autophosphorylation GO:0046777 157 64 0,000 0,02491978 0,02690191 ! response to peptide hormone stimulus GO:0043434 129 64 0,000 0,02491978 0,02689003 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,02530454 0,02729315 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,02530454 0,0272811 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,02530454 0,02726907 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,02530454 0,02725705 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,02530454 0,02724503 ! positive regulation of cell motion GO:0051272 157 65 0,000 0,02530454 0,02723303 ! ear development GO:0043583 114 66 0,000 0,02568915 0,02763478 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,02568915 0,02762262 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,02568915 0,02761047 ! gonad development GO:0008406 115 66 0,000 0,02568915 0,02759833 ! steroid hormone receptor signaling pathway GO:0030518 146 66 0,000 0,02568915 0,02758619 ! negative regulation of cell growth GO:0030308 142 67 0,000 0,02607362 0,02798676 ! activation of MAPK activity GO:0000187 124 67 0,000 0,02607362 0,02797447 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,02607362 0,02796219 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,02607362 0,02794992 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,02607362 0,02793766 ! secondary metabolic process GO:0019748 125 67 0,000 0,02607362 0,02792541 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,02607362 0,02791317 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,02645796 0,02831221 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,02645796 0,02829982 ! hexose catabolic process GO:0019320 113 68 0,000 0,02645796 0,02828743 ! extracellular matrix organization GO:0030198 146 68 0,000 0,02645796 0,02827506 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,02645796 0,0282627 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,02645796 0,02825034 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,02645796 0,028238 ! viral reproduction GO:0016032 142 68 0,000 0,02645796 0,02822567 ! regulation of lipase activity GO:0060191 137 68 0,000 0,02645796 0,02821335 ! adaptive immune response GO:0002250 126 68 0,000 0,02645796 0,02820104 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cell projection assembly GO:0030031 138 68 0,000 0,02645796 0,02818874 ! negative regulation of cell size GO:0045792 144 69 0,000 0,02684215 0,0285856 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,02684215 0,02857314 ! negative regulation of protein kinase activity GO:0006469 144 69 0,000 0,02684215 0,0285607 ! lung development GO:0030324 165 69 0,000 0,02684215 0,02854827 ! urogenital system development GO:0001655 149 69 0,000 0,02684215 0,02853584 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,02684215 0,02852343 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 0,000 0,02684215 0,02851103 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,02684215 0,02849864 ! developmental maturation GO:0021700 128 69 0,000 0,02684215 0,02848626 ! single fertilization GO:0007338 83 69 0,000 0,02684215 0,02847389 ! negative regulation of kinase activity GO:0033673 145 70 0,000 0,0272262 0,02886875 ! cell redox homeostasis GO:0045454 114 70 0,000 0,0272262 0,02885623 ! germ cell development GO:0007281 133 70 0,000 0,0272262 0,02884371 ! activation of immune response GO:0002253 120 70 0,000 0,0272262 0,02883121 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,0272262 0,02881872 ! cell cycle checkpoint GO:0000075 145 71 0,000 0,02761011 0,02921243 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,02761011 0,02919978 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,02761011 0,02918715 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 0,000 0,02761011 0,02917452 ! appendage morphogenesis GO:0035107 150 72 0,000 0,02799388 0,02956725 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,02799388 0,02955447 ! respiratory tube development GO:0030323 171 72 0,000 0,02799388 0,0295417 ! actin filament organization GO:0007015 167 72 0,000 0,02799388 0,02952895 ! B cell activation GO:0042113 179 72 0,000 0,02799388 0,0295162 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,02799388 0,02950347 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,02799388 0,02949075 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,02799388 0,02947804 ! appendage development GO:0048736 151 73 0,000 0,02837751 0,02986913 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,02837751 0,02985627 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,02837751 0,02984341 ! regulation of immune effector process GO:0002697 156 73 0,000 0,02837751 0,02983057 ! acute inflammatory response GO:0002526 118 74 0,000 0,028761 0,03022069 ! amino acid transport GO:0006865 148 74 0,000 0,028761 0,0302077 ! regulation of caspase activity GO:0043281 136 74 0,000 0,028761 0,03019472 ! negative regulation of transferase activity GO:0051348 155 74 0,000 0,028761 0,03018175 ! respiratory system development GO:0060541 175 74 0,000 0,028761 0,03016879 ! regulation of transcription factor activity GO:0051090 137 75 0,000 0,02914434 0,03055778 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 143 75 0,000 0,02914434 0,03054467 ! reproductive structure development GO:0048608 131 75 0,000 0,02914434 0,03053157 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,02914434 0,03051849 ! eye development GO:0001654 155 75 0,000 0,02914434 0,03050541 ! axon guidance GO:0007411 162 75 0,000 0,02914434 0,03049235 ! rhythmic process GO:0048511 142 75 0,000 0,02914434 0,03047929 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,02952755 0,03086684 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,02952755 0,03085364 ! learning or memory GO:0007611 161 76 0,000 0,02952755 0,03084045 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,02952755 0,03082727 ! regulation of blood pressure GO:0008217 134 76 0,000 0,02952755 0,0308141 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,02952755 0,03080094 ! amine catabolic process GO:0009310 136 77 0,000 0,02991062 0,03118721 ! neurotransmitter transport GO:0006836 142 77 0,000 0,02991062 0,03117391 ! phosphoinositide metabolic process GO:0030384 146 77 0,000 0,02991062 0,03116061 ! regulation of endopeptidase activity GO:0052548 141 77 0,000 0,02991062 0,03114733 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,02991062 0,03113406 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,02991062 0,0311208 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,02991062 0,03110755 ! regulation of catabolic process GO:0009894 173 77 0,000 0,02991062 0,03109431 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,03029354 0,031479 ! antigen processing and presentation GO:0019882 117 78 0,000 0,03029354 0,03146562 ! fertilization GO:0009566 99 78 0,000 0,03029354 0,03145224 ! positive regulation of lymphocyte activation GO:0051251 142 78 0,000 0,03029354 0,03143888 ! blood coagulation GO:0007596 151 79 0,000 0,03067633 0,03182262 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,03067633 0,03180911 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,03067633 0,03179562 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,03067633 0,03178213 ! protein oligomerization GO:0051259 149 79 0,000 0,03067633 0,03176866 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,03067633 0,0317552 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,03105898 0,03213769 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,03105898 0,03212408 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,03105898 0,03211049 ! muscle cell differentiation GO:0042692 178 81 0,000 0,03144148 0,03249219 ! response to hypoxia GO:0001666 178 81 0,000 0,03144148 0,03247845 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,03144148 0,03246472 ! regulation of peptidase activity GO:0052547 150 82 0,000 0,03182385 0,03284565 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,03182385 0,03283178 ! protein import into nucleus GO:0006606 174 82 0,000 0,03182385 0,03281792 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,03220607 0,03319807 ! exocytosis GO:0006887 153 83 0,000 0,03220607 0,03318407 ! response to drug GO:0042493 149 83 0,000 0,03220607 0,03317008 ! response to oxygen levels GO:0070482 183 83 0,000 0,03220607 0,0331561 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,03220607 0,03314214 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,03220607 0,03312818 ! nuclear import GO:0051170 177 83 0,000 0,03220607 0,03311424 ! inorganic anion transport GO:0015698 156 83 0,000 0,03220607 0,03310031 ! T cell activation GO:0042110 189 84 0,000 0,03258816 0,03347892 ! response to nutrient GO:0007584 135 84 0,000 0,03258816 0,03346485 ! digestion GO:0007586 130 84 0,000 0,03258816 0,03345078 ! hemostasis GO:0007599 165 85 0,000 0,0329701 0,03382863 ! negative regulation of transport GO:0051051 164 85 0,000 0,0329701 0,03381442 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,0329701 0,03380023 ! negative regulation of growth GO:0045926 168 85 0,000 0,0329701 0,03378606 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,0329701 0,03377189 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,0329701 0,03375774 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,0329701 0,03374359 ! cellular response to hormone stimulus GO:0032870 182 85 0,000 0,0329701 0,03372946 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,03335191 0,03410578 ! regulation of lyase activity GO:0051339 169 86 0,000 0,03335191 0,03409151 ! positive regulation of cell activation GO:0050867 161 86 0,000 0,03335191 0,03407725 GO:0002696|positive regulation of leukocyte activation, ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,03373357 0,03445281 ! mitochondrion organization GO:0007005 159 87 0,000 0,03373357 0,03443841 ! alcohol catabolic process GO:0046164 142 87 0,000 0,03373357 0,03442402 ! nucleosome assembly GO:0006334 126 87 0,000 0,03373357 0,03440965 ! regulation of protein transport GO:0051223 165 87 0,000 0,03373357 0,03439529 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 143 88 0,000 0,0341151 0,03476979 ! amine biosynthetic process GO:0009309 146 88 0,000 0,0341151 0,03475529 ! sensory perception of smell GO:0007608 117 88 0,000 0,0341151 0,0347408 ! chromatin assembly GO:0031497 128 88 0,000 0,0341151 0,03472632 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,0341151 0,03471186 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,03449648 0,03508531 ! regulation of DNA binding GO:0051101 167 89 0,000 0,03449648 0,0350707 ! tube morphogenesis GO:0035239 194 89 0,000 0,03449648 0,03505612 ! cellular defense response GO:0006968 123 89 0,000 0,03449648 0,03504154 ! protein localization in nucleus GO:0034504 192 89 0,000 0,03449648 0,03502698 ! regulation of neurological system process GO:0031644 175 89 0,000 0,03449648 0,03501242 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,03487773 0,03538467 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,03525883 0,03575647 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! ossification GO:0001503 205 91 0,000 0,03525883 0,03574163 ! gland development GO:0048732 220 91 0,000 0,03525883 0,0357268 ! defense response to bacterium GO:0042742 112 91 0,000 0,03525883 0,03571199 ! bone development GO:0060348 206 92 0,000 0,0356398 0,03608289 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,0356398 0,03606795 ! regulation of cell adhesion GO:0030155 241 92 0,000 0,0356398 0,03605301 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,03602062 0,03642317 ! amine transport GO:0015837 181 93 0,000 0,03602062 0,0364081 ! positive regulation of MAP kinase activity GO:0043406 174 93 0,000 0,03602062 0,03639305 ! vitamin metabolic process GO:0006766 153 93 0,000 0,03602062 0,036378 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,03640131 0,03674727 ! female pregnancy GO:0007565 166 94 0,000 0,03640131 0,03673209 ! sterol metabolic process GO:0016125 166 94 0,000 0,03640131 0,03671693 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,03640131 0,03670177 ! regulation of membrane potential GO:0042391 179 94 0,000 0,03640131 0,03668663 ! regulation of defense response GO:0031347 171 95 0,000 0,03678186 0,03705488 ! nucleosome organization GO:0034728 143 95 0,000 0,03678186 0,0370396 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,03678186 0,03702434 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,03678186 0,03700909 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,03678186 0,03699386 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,03678186 0,03697863 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,03678186 0,03696342 ! sex differentiation GO:0007548 171 96 0,000 0,03716226 0,03733035 ! regulation of T cell activation GO:0050863 175 96 0,000 0,03716226 0,03731501 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,03754253 0,03768135 ! transcription initiation GO:0006352 171 97 0,000 0,03754253 0,03766587 ! regulation of protein localization GO:0032880 188 97 0,000 0,03754253 0,03765041 ! leukocyte differentiation GO:0002521 232 98 0,000 0,03792266 0,03801603 ! forebrain development GO:0030900 210 98 0,000 0,03792266 0,03800043 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,03792266 0,03798485 ! skeletal muscle tissue development GO:0007519 223 100 0,000 0,0386825 0,03873006 GO:0060538|skeletal muscle organ development, ! mRNA transport GO:0051028 185 100 0,000 0,0386825 0,03871419 ! positive regulation of immune response GO:0050778 175 100 0,000 0,0386825 0,03869834 ! hormone metabolic process GO:0042445 171 100 0,000 0,0386825 0,0386825