pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-b2/out-0.05-06-0.01-300-run-b2//th1-pval-1e-01-06-th2-pval-1e-02-02-th3-pval-1e-01-01-run-b2/go_data/23759-2-real-Pawitan_GPL96-GPL97-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! negative regulation of protein ubiquitination GO:0031397 9 5 1,000 4,625E-06 0,01112725 ! activation of Ras GTPase activity GO:0032856 10 5 1,000 4,625E-06 5,564E-03 GO:0032862|activation of Rho GTPase activity, ! positive regulation of cell cycle GO:0045787 89 48 2,000 4,952E-06 3,972E-03 ! protein refolding GO:0042026 15 6 1,000 6,934E-06 4,171E-03 ! positive regulation of mitotic cell cycle GO:0045931 12 7 1,000 9,704E-06 4,67E-03 ! spindle checkpoint GO:0031577 15 7 1,000 9,704E-06 3,891E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 1,293E-05 4,445E-03 ! chaperone-mediated protein complex assembly GO:0051131 13 8 1,000 1,293E-05 3,89E-03 ! outer mitochondrial membrane organization GO:0007008 16 8 1,000 1,293E-05 3,457E-03 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! regulation of focal adhesion formation GO:0051893 22 8 1,000 1,293E-05 3,112E-03 ! establishment of chromosome localization GO:0051303 12 8 1,000 1,293E-05 2,829E-03 GO:0050000|chromosome localization, ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 1,000 1,662E-05 3,333E-03 ! regulation of phosphatase activity GO:0010921 28 10 1,000 2,077E-05 3,844E-03 ! regulation of stress fiber formation GO:0051492 30 10 1,000 2,077E-05 3,569E-03 ! positive regulation of Rho GTPase activity GO:0032321 24 10 1,000 2,077E-05 3,331E-03 ! regulation of actin filament bundle formation GO:0032231 33 11 1,000 2,537E-05 3,815E-03 ! response to unfolded protein GO:0006986 131 85 2,000 2,781E-05 3,937E-03 ! regulation of exit from mitosis GO:0007096 17 12 1,000 3,043E-05 4,068E-03 ! response to protein stimulus GO:0051789 149 91 2,000 3,412E-05 4,321E-03 ! positive regulation of Ras GTPase activity GO:0032320 35 13 1,000 3,595E-05 4,325E-03 ! interphase of mitotic cell cycle GO:0051329 209 95 2,000 3,88E-05 4,446E-03 ! positive regulation of GTPase activity GO:0043547 36 14 1,000 4,193E-05 4,585E-03 ! negative regulation of caspase activity GO:0043154 22 14 1,000 4,193E-05 4,386E-03 ! interphase GO:0051325 213 98 2,000 4,258E-05 4,269E-03 ! regulation of protein ubiquitination GO:0031396 25 16 1,000 5,524E-05 5,316E-03 ! protein polyubiquitination GO:0000209 34 16 1,000 5,524E-05 5,112E-03 ! regulation of dephosphorylation GO:0035303 43 16 1,000 5,524E-05 4,923E-03 ! negative regulation of peptidase activity GO:0010466 27 17 1,000 6,258E-05 5,377E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 6,258E-05 5,192E-03 ! cellular response to unfolded protein GO:0034620 33 19 1,000 7,862E-05 6,305E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 1,000 8,732E-05 6,777E-03 ! negative regulation of translation GO:0017148 29 20 1,000 8,732E-05 6,565E-03 ! regulation of Rho GTPase activity GO:0032319 43 21 1,000 9,647E-05 7,033E-03 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 1,161E-04 8,218E-03 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 1,161E-04 7,983E-03 GO:0010810|regulation of cell-substrate adhesion, ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 1,376E-04 9,195E-03 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 1,376E-04 8,947E-03 ! positive regulation of nuclear division GO:0051785 40 26 1,000 1,49E-04 9,433E-03 GO:0045840|positive regulation of mitosis, ! fat cell differentiation GO:0045444 50 27 1,000 1,608E-04 9,922E-03 ! mitochondrial membrane organization GO:0007006 57 27 1,000 1,608E-04 9,674E-03 ! negative regulation of protein modification process GO:0031400 60 28 1,000 1,731E-04 0,01016003 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 1,731E-04 9,918E-03 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 2,717E-04 0,015204 ! RNA export from nucleus GO:0006405 56 37 1,000 3,039E-04 0,0166175 ! cytokinesis GO:0000910 72 40 1,000 3,555E-04 0,01900547 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 1,000 4,705E-04 0,02460844 ! response to insulin stimulus GO:0032868 95 46 1,000 4,705E-04 0,02408486 ! response to calcium ion GO:0051592 81 47 1,000 4,912E-04 0,02462088 ! mitochondrial transport GO:0006839 82 48 1,000 5,123E-04 0,02515647 ! response to UV GO:0009411 104 53 1,000 6,246E-04 0,03005409 ! nuclear export GO:0051168 97 55 1,000 6,725E-04 0,03172603 ! positive regulation of organelle organization GO:0010638 100 56 1,000 6,971E-04 0,0322548 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 1,000 7,222E-04 0,03278322 ! establishment of organelle localization GO:0051656 109 59 1,000 7,735E-04 0,03446561 ! response to peptide hormone stimulus GO:0043434 122 61 1,000 8,266E-04 0,03616207 ! regulation of mitosis GO:0007088 105 63 1,000 8,815E-04 0,03787166 GO:0051783|regulation of nuclear division, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 1,026E-03 0,04330789 ! cell cycle checkpoint GO:0000075 137 69 1,000 1,056E-03 0,04381329 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 1,056E-03 0,04307069 ! regulation of caspase activity GO:0043281 122 72 1,000 1,149E-03 0,04608593 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 1,000 1,149E-03 0,04533042 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 1,149E-03 0,04459929 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 1,000 1,149E-03 0,04389136 ! regulation of actin cytoskeleton organization GO:0032956 149 74 1,000 1,213E-03 0,04561825 ! regulation of endopeptidase activity GO:0052548 125 74 1,000 1,213E-03 0,04491644 ! organelle localization GO:0051640 136 74 1,000 1,213E-03 0,04423588 ! regulation of actin filament-based process GO:0032970 152 77 1,000 1,313E-03 0,04714619 ! positive regulation of ligase activity GO:0051351 124 77 1,000 1,313E-03 0,04645286 ! regulation of peptidase activity GO:0052547 134 79 1,000 1,381E-03 0,04816427 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 1,000 1,381E-03 0,04747621 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 1,381E-03 0,04680753 ! response to metal ion GO:0010038 140 80 1,000 1,416E-03 0,04732108 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 1,451E-03 0,04783436 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of ligase activity GO:0051340 142 84 1,000 1,56E-03 0,05070684 ! response to inorganic substance GO:0010035 153 86 1,000 1,634E-03 0,05241221 ! mitochondrion organization GO:0007005 148 86 1,000 1,634E-03 0,05172257 ! positive regulation of protein modification process GO:0031401 136 88 1,000 1,71E-03 0,05342235 ! regulation of cell adhesion GO:0030155 212 89 1,000 1,748E-03 0,05392717 ! regulation of cell cycle process GO:0010564 149 90 1,000 1,787E-03 0,0544318 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 1,907E-03 0,05734312 GO:0010498|proteasomal protein catabolic process, ! regulation of Rho protein signal transduction GO:0035023 213 95 1,000 1,988E-03 0,05906123 ! protein ubiquitination GO:0016567 217 97 1,000 2,072E-03 0,0607856 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 3,482E-03 0,10092954 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 3,482E-03 0,09972799 ! positive regulation of helicase activity GO:0051096 11 5 0,000 3,482E-03 0,09855472 ! neuron fate determination GO:0048664 7 5 0,000 3,482E-03 0,09740874 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 3,482E-03 0,0962891 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 3,482E-03 0,0951949 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 3,482E-03 0,0941253 ! polyol transport GO:0015791 12 5 0,000 3,482E-03 0,09307946 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 3,482E-03 0,09205661 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 3,482E-03 0,09105599 ! response to superoxide GO:0000303 10 5 0,000 3,482E-03 0,0900769 ! negative regulation of bone resorption GO:0045779 10 5 0,000 3,482E-03 0,08911863 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 3,482E-03 0,08818054 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 3,482E-03 0,08726199 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 3,482E-03 0,08636239 ! female meiosis GO:0007143 7 5 0,000 3,482E-03 0,08548114 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 3,482E-03 0,08461769 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 3,482E-03 0,08377151 ! cobalt ion transport GO:0006824 11 5 0,000 3,482E-03 0,08294209 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 3,482E-03 0,08212894 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 3,482E-03 0,08133157 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 3,482E-03 0,08054953 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 3,482E-03 0,07978239 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 3,482E-03 0,07902973 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 3,482E-03 0,07829113 ! embryonic camera-type eye development GO:0031076 10 5 0,000 3,482E-03 0,07756622 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 3,482E-03 0,0768546 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 3,482E-03 0,07615592 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 3,482E-03 0,07546983 ! adaptation of signaling pathway GO:0022401 7 5 0,000 3,482E-03 0,07479599 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 3,482E-03 0,07413408 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 3,482E-03 0,07348378 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 3,482E-03 0,07284479 ! negative chemotaxis GO:0050919 14 5 0,000 3,482E-03 0,07221682 ! positive regulation of histone modification GO:0031058 5 5 0,000 3,482E-03 0,07159958 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 3,482E-03 0,07099281 ! sensory perception of bitter taste GO:0050913 7 5 0,000 3,482E-03 0,07039623 ! behavioral response to pain GO:0048266 9 5 0,000 3,482E-03 0,0698096 ! clathrin coat assembly GO:0048268 14 5 0,000 3,482E-03 0,06923266 ! Notch receptor processing GO:0007220 8 5 0,000 3,482E-03 0,06866518 ! regulation of dopamine uptake GO:0051584 9 5 0,000 3,482E-03 0,06810692 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 3,482E-03 0,06755767 ! micturition GO:0060073 9 5 0,000 3,482E-03 0,06701721 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 3,482E-03 0,06648533 ! copulation GO:0007620 9 5 0,000 3,482E-03 0,06596182 ! glial cell fate commitment GO:0021781 13 5 0,000 3,482E-03 0,0654465 ! protein maturation by protein folding GO:0022417 13 5 0,000 3,482E-03 0,06493916 ! spermidine metabolic process GO:0008216 7 5 0,000 3,482E-03 0,06443963 ! regulation of potassium ion transport GO:0043266 10 5 0,000 3,482E-03 0,06394772 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 3,482E-03 0,06346327 ! apoptotic cell clearance GO:0043277 20 5 0,000 3,482E-03 0,0629861 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 3,482E-03 0,06251606 ! lipoprotein particle clearance GO:0034381 10 5 0,000 3,482E-03 0,06205297 ! grooming behavior GO:0007625 6 5 0,000 3,482E-03 0,0615967 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 3,482E-03 0,06114709 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 3,482E-03 0,060704 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 3,482E-03 0,06026728 ! response to protozoan GO:0001562 10 5 0,000 3,482E-03 0,0598368 ! positive regulation of glycolysis GO:0045821 14 5 0,000 3,482E-03 0,05941242 ! lymph vessel development GO:0001945 10 5 0,000 3,482E-03 0,05899402 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 3,482E-03 0,05858148 ! endochondral ossification GO:0001958 16 5 0,000 3,482E-03 0,05817466 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 3,482E-03 0,05777346 ! parathyroid gland development GO:0060017 13 5 0,000 3,482E-03 0,05737775 ! anagen GO:0042640 6 5 0,000 3,482E-03 0,05698742 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 3,482E-03 0,05660237 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 3,482E-03 0,05622249 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 3,482E-03 0,05584768 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 3,482E-03 0,05547782 ! dorsal spinal cord development GO:0021516 7 5 0,000 3,482E-03 0,05511284 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 3,482E-03 0,05475262 ! sphingoid catabolic process GO:0046521 6 5 0,000 3,482E-03 0,05439709 ! skeletal myofibril assembly GO:0014866 10 5 0,000 3,482E-03 0,05404614 ! smooth muscle tissue development GO:0048745 28 5 0,000 3,482E-03 0,05369969 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 3,482E-03 0,05335765 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 3,482E-03 0,05301995 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 3,482E-03 0,05268649 ! cardiac muscle fiber development GO:0048739 10 5 0,000 3,482E-03 0,0523572 ! transepithelial chloride transport GO:0030321 9 5 0,000 3,482E-03 0,052032 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 3,482E-03 0,05171081 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 3,482E-03 0,05139357 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 3,482E-03 0,05108019 ! neutrophil mediated immunity GO:0002446 7 5 0,000 3,482E-03 0,05077061 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 3,482E-03 0,05046477 ! histidine catabolic process GO:0006548 6 5 0,000 3,482E-03 0,05016258 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 3,482E-03 0,049864 ! microvillus organization GO:0032528 7 5 0,000 3,482E-03 0,04956894 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 3,482E-03 0,04927736 ! L-serine biosynthetic process GO:0006564 6 5 0,000 3,482E-03 0,04898919 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 3,482E-03 0,04870437 ! tryptophan metabolic process GO:0006568 9 5 0,000 3,482E-03 0,04842284 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 3,482E-03 0,04814455 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 3,482E-03 0,04786944 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 3,482E-03 0,04759745 ! polyol catabolic process GO:0046174 7 5 0,000 3,482E-03 0,04732854 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 3,482E-03 0,04706265 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 3,482E-03 0,04679973 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 3,482E-03 0,04653973 ! muscle cell migration GO:0014812 8 5 0,000 3,482E-03 0,0462826 ! mitochondrial fission GO:0000266 8 5 0,000 3,482E-03 0,0460283 ! sister chromatid cohesion GO:0007062 12 5 0,000 3,482E-03 0,04577678 ! mRNA transcription GO:0009299 9 5 0,000 3,482E-03 0,045528 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 3,482E-03 0,0452819 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 3,482E-03 0,04503845 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 3,482E-03 0,0447976 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 3,482E-03 0,04455932 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 3,482E-03 0,04432355 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 3,482E-03 0,04409027 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 3,482E-03 0,04385943 ! response to food GO:0032094 6 5 0,000 3,482E-03 0,043631 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 3,482E-03 0,04340493 ! positive regulation of transporter activity GO:0032411 8 5 0,000 3,482E-03 0,04318119 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 3,482E-03 0,04295975 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 3,482E-03 0,04274057 ! paraxial mesoderm development GO:0048339 14 5 0,000 3,482E-03 0,04252361 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 3,482E-03 0,04230885 ! forebrain neuron development GO:0021884 13 5 0,000 3,482E-03 0,04209624 ! lipoprotein catabolic process GO:0042159 11 5 0,000 3,482E-03 0,04188576 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 3,482E-03 0,04167737 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 3,482E-03 0,04147105 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 3,482E-03 0,04126676 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 3,482E-03 0,04106447 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 3,482E-03 0,04086415 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 3,482E-03 0,04066578 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 3,482E-03 0,04046933 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 3,482E-03 0,04027477 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 3,482E-03 0,04008206 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 3,482E-03 0,0398912 ! basic amino acid transport GO:0015802 11 5 0,000 3,482E-03 0,03970214 ! cellular glucose homeostasis GO:0001678 5 5 0,000 3,482E-03 0,03951487 ! early endosome to late endosome transport GO:0045022 12 5 0,000 3,482E-03 0,03932935 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 3,482E-03 0,03914557 ! depyrimidination GO:0045008 10 5 0,000 3,482E-03 0,03896349 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 3,482E-03 0,03878311 ! regulation of centrosome cycle GO:0046605 7 5 0,000 3,482E-03 0,03860438 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 3,482E-03 0,0384273 ! zinc ion homeostasis GO:0055069 8 5 0,000 3,482E-03 0,03825183 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 3,482E-03 0,03807796 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 3,482E-03 0,03790566 ! forebrain morphogenesis GO:0048853 13 5 0,000 3,482E-03 0,03773492 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 3,482E-03 0,0375657 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 3,482E-03 0,037398 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 3,482E-03 0,03723178 ! peptidyl-arginine modification GO:0018195 9 5 0,000 3,482E-03 0,03706704 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 3,482E-03 0,03690375 ! positive regulation of organ growth GO:0046622 6 5 0,000 3,482E-03 0,03674189 ! response to arsenic GO:0046685 10 5 0,000 3,482E-03 0,03658145 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 3,482E-03 0,0364224 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 3,482E-03 0,03626472 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 3,482E-03 0,03610841 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 3,482E-03 0,03595344 ! response to cadmium ion GO:0046686 7 5 0,000 3,482E-03 0,03579979 ! bile acid biosynthetic process GO:0006699 6 5 0,000 3,482E-03 0,03564745 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 3,482E-03 0,0354964 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 3,482E-03 0,03534663 ! decidualization GO:0046697 11 5 0,000 3,482E-03 0,03519812 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 3,482E-03 0,03505084 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 3,482E-03 0,0349048 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 3,482E-03 0,03475996 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 3,482E-03 0,03461633 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 3,482E-03 0,03447387 ! base conversion or substitution editing GO:0016553 5 5 0,000 3,482E-03 0,03433259 ! neural tube patterning GO:0021532 7 5 0,000 3,482E-03 0,03419245 ! embryonic cleavage GO:0040016 6 5 0,000 3,482E-03 0,03405346 ! peroxisome fission GO:0016559 5 5 0,000 3,482E-03 0,03391559 ! histone demethylation GO:0016577 10 5 0,000 3,482E-03 0,03377884 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 3,482E-03 0,03364318 ! mitotic recombination GO:0006312 9 5 0,000 3,482E-03 0,03350861 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 3,482E-03 0,03337511 ! metaphase plate congression GO:0051310 7 5 0,000 3,482E-03 0,03324266 ! regulation of sterol transport GO:0032371 7 5 0,000 3,482E-03 0,03311127 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 3,482E-03 0,03298091 ! enteric nervous system development GO:0048484 8 5 0,000 3,482E-03 0,03285157 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 3,482E-03 0,03272325 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 3,482E-03 0,03259592 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 3,482E-03 0,03246958 ! muscle cell proliferation GO:0033002 11 5 0,000 3,482E-03 0,03234421 ! skeletal muscle regeneration GO:0043403 8 5 0,000 3,482E-03 0,03221981 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 3,482E-03 0,03209637 ! plasminogen activation GO:0031639 5 5 0,000 3,482E-03 0,03197386 ! B cell homeostasis GO:0001782 13 5 0,000 3,482E-03 0,03185229 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 3,482E-03 0,03173163 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 3,482E-03 0,03161189 ! metaphase GO:0051323 8 5 0,000 3,482E-03 0,03149305 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 3,482E-03 0,0313751 ! cellular response to nutrient GO:0031670 8 5 0,000 3,482E-03 0,03125803 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 3,482E-03 0,03114183 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 3,482E-03 0,03102649 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 3,482E-03 0,030912 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 3,482E-03 0,03079835 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 3,482E-03 0,03068554 ! response to redox state GO:0051775 5 5 0,000 3,482E-03 0,03057355 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 3,482E-03 0,03046237 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 3,482E-03 0,030352 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 3,482E-03 0,03024242 ! regulation of telomerase activity GO:0051972 6 5 0,000 3,482E-03 0,03013364 ! galactolipid metabolic process GO:0019374 7 5 0,000 3,482E-03 0,03002563 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 3,482E-03 0,0299184 ! porphyrin catabolic process GO:0006787 12 5 0,000 3,482E-03 0,02981193 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 3,482E-03 0,02970621 ! striatum development GO:0021756 9 5 0,000 3,482E-03 0,02960124 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 3,482E-03 0,02949701 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 3,482E-03 0,02939351 ! glial cell migration GO:0008347 11 5 0,000 3,482E-03 0,02929074 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 3,482E-03 0,02918868 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 3,482E-03 0,02908733 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 3,482E-03 0,02898668 ! somatic stem cell maintenance GO:0035019 15 5 0,000 3,482E-03 0,02888673 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 3,482E-03 0,02878746 ! negative regulation of lipase activity GO:0060192 8 5 0,000 3,482E-03 0,02868887 ! neuroprotection GO:0043526 6 5 0,000 3,482E-03 0,02859096 ! neural plate development GO:0001840 8 5 0,000 3,482E-03 0,02849371 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 3,482E-03 0,02839712 ! regulation of sensory perception GO:0051931 7 5 0,000 3,482E-03 0,02830119 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 3,482E-03 0,0282059 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 3,482E-03 0,02811125 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 3,482E-03 0,02801723 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 3,482E-03 0,02792384 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 3,482E-03 0,02783107 ! sequestering of calcium ion GO:0051208 7 5 0,000 3,482E-03 0,02773891 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 3,482E-03 0,02764736 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 3,482E-03 0,02755642 ! spindle assembly GO:0051225 6 5 0,000 3,482E-03 0,02746607 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 3,482E-03 0,02737631 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 3,482E-03 0,02728714 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 3,482E-03 0,02719854 ! drug metabolic process GO:0017144 6 5 0,000 3,482E-03 0,02711052 ! stem cell division GO:0017145 11 5 0,000 3,482E-03 0,02702307 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 3,482E-03 0,02693618 ! organ regeneration GO:0031100 7 5 0,000 3,482E-03 0,02684984 ! carnitine metabolic process GO:0009437 7 5 0,000 3,482E-03 0,02676406 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 3,482E-03 0,02667883 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 3,482E-03 0,02659413 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 4,177E-03 0,03180141 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 4,177E-03 0,03170109 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 4,177E-03 0,0316014 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 4,177E-03 0,03150234 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 4,177E-03 0,03140389 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 4,177E-03 0,03130606 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 4,177E-03 0,03120884 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 4,177E-03 0,03111221 ! sleep GO:0030431 13 6 0,000 4,177E-03 0,03101619 ! response to oxygen radical GO:0000305 11 6 0,000 4,177E-03 0,03092075 ! positive regulation of axon extension GO:0045773 11 6 0,000 4,177E-03 0,0308259 ! myoblast cell fate commitment GO:0048625 16 6 0,000 4,177E-03 0,03073164 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 4,177E-03 0,03063794 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 4,177E-03 0,03054482 ! regulation of interferon-beta production GO:0032648 8 6 0,000 4,177E-03 0,03045226 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 4,177E-03 0,03036026 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 4,177E-03 0,03026881 ! forebrain regionalization GO:0021871 8 6 0,000 4,177E-03 0,03017791 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 4,177E-03 0,03008756 ! male meiosis GO:0007140 7 6 0,000 4,177E-03 0,02999775 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 4,177E-03 0,02990847 ! response to zinc ion GO:0010043 9 6 0,000 4,177E-03 0,02981972 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 4,177E-03 0,02973149 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 4,177E-03 0,02964379 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 4,177E-03 0,0295566 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 4,177E-03 0,02946993 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 4,177E-03 0,02938376 ! malate metabolic process GO:0006108 11 6 0,000 4,177E-03 0,02929809 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 4,177E-03 0,02921292 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 4,177E-03 0,02912825 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 4,177E-03 0,02904406 ! opsonization GO:0008228 8 6 0,000 4,177E-03 0,02896036 ! mating behavior GO:0007617 7 6 0,000 4,177E-03 0,02887714 ! neuron remodeling GO:0016322 15 6 0,000 4,177E-03 0,0287944 ! erythrocyte maturation GO:0043249 7 6 0,000 4,177E-03 0,02871213 ! embryonic hemopoiesis GO:0035162 14 6 0,000 4,177E-03 0,02863033 ! equilibrioception GO:0050957 14 6 0,000 4,177E-03 0,02854899 ! protein amino acid dealkylation GO:0008214 12 6 0,000 4,177E-03 0,02846812 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 4,177E-03 0,0283877 ! photoreceptor cell development GO:0042461 10 6 0,000 4,177E-03 0,02830773 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 4,177E-03 0,02822822 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 4,177E-03 0,02814915 ! response to interferon-gamma GO:0034341 15 6 0,000 4,177E-03 0,02807052 ! toxin metabolic process GO:0009404 11 6 0,000 4,177E-03 0,02799233 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 4,177E-03 0,02791457 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 4,177E-03 0,02783724 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 4,177E-03 0,02776035 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 4,177E-03 0,02768387 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 4,177E-03 0,02760782 ! cGMP-mediated signaling GO:0019934 13 6 0,000 4,177E-03 0,02753218 ! activation of MAPKKK activity GO:0000185 12 6 0,000 4,177E-03 0,02745695 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 4,177E-03 0,02738214 ! thymic T cell selection GO:0045061 12 6 0,000 4,177E-03 0,02730773 ! protein lipoylation GO:0009249 10 6 0,000 4,177E-03 0,02723373 ! cysteine metabolic process GO:0006534 10 6 0,000 4,177E-03 0,02716012 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 4,177E-03 0,02708691 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 4,177E-03 0,0270141 ! glutamate catabolic process GO:0006538 10 6 0,000 4,177E-03 0,02694168 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 4,177E-03 0,02686964 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 4,177E-03 0,02679799 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 4,177E-03 0,02672672 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 4,177E-03 0,02665582 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 4,177E-03 0,0265853 ! hyperosmotic response GO:0006972 9 6 0,000 4,177E-03 0,02651516 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 4,177E-03 0,02644538 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 4,177E-03 0,02637597 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 4,177E-03 0,02630692 ! urea metabolic process GO:0019627 7 6 0,000 4,177E-03 0,02623824 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 4,177E-03 0,02616991 ! neutrophil activation GO:0042119 8 6 0,000 4,177E-03 0,02610193 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 4,177E-03 0,02603431 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 4,177E-03 0,02596704 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 4,177E-03 0,02590012 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 4,177E-03 0,02583353 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 4,177E-03 0,02576729 ! neuron apoptosis GO:0051402 9 6 0,000 4,177E-03 0,02570139 ! nucleoside salvage GO:0043174 9 6 0,000 4,177E-03 0,02563583 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 4,177E-03 0,0255706 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 4,177E-03 0,0255057 ! T cell mediated immunity GO:0002456 16 6 0,000 4,177E-03 0,02544113 ! negative regulation of platelet activation GO:0010544 9 6 0,000 4,177E-03 0,02537688 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 4,177E-03 0,02531296 ! carnitine transport GO:0015879 10 6 0,000 4,177E-03 0,02524936 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 4,177E-03 0,02518608 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 4,177E-03 0,02512311 ! positive regulation of exocytosis GO:0045921 8 6 0,000 4,177E-03 0,02506046 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 4,177E-03 0,02499812 ! 5S class rRNA transcription GO:0042791 11 6 0,000 4,177E-03 0,02493609 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 4,177E-03 0,02487437 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 4,177E-03 0,02481295 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 4,177E-03 0,02475183 ! sodium ion homeostasis GO:0055078 11 6 0,000 4,177E-03 0,02469102 ! establishment of spindle localization GO:0051293 12 6 0,000 4,177E-03 0,0246305 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 4,177E-03 0,02457028 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 4,177E-03 0,02451035 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 4,177E-03 0,02445072 ! neural nucleus development GO:0048857 14 6 0,000 4,177E-03 0,02439137 ! response to UV-C GO:0010225 11 6 0,000 4,177E-03 0,02433231 ! astrocyte development GO:0014002 15 6 0,000 4,177E-03 0,02427354 ! protein targeting to lysosome GO:0006622 10 6 0,000 4,177E-03 0,02421505 ! purine base biosynthetic process GO:0009113 17 6 0,000 4,177E-03 0,02415684 ! interaction with symbiont GO:0051702 13 6 0,000 4,177E-03 0,02409891 ! regulation of dendrite development GO:0050773 16 6 0,000 4,177E-03 0,02404126 ! skeletal muscle contraction GO:0003009 6 6 0,000 4,177E-03 0,02398388 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 4,177E-03 0,02392677 ! response to copper ion GO:0046688 10 6 0,000 4,177E-03 0,02386994 ! response to exogenous dsRNA GO:0043330 10 6 0,000 4,177E-03 0,02381338 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 4,177E-03 0,02375708 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 4,177E-03 0,02370105 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 4,177E-03 0,02364528 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 4,177E-03 0,02358978 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 4,177E-03 0,02353453 ! regulation of dopamine secretion GO:0014059 14 6 0,000 4,177E-03 0,02347954 ! nucleoside catabolic process GO:0009164 7 6 0,000 4,177E-03 0,02342481 ! hair follicle maturation GO:0048820 7 6 0,000 4,177E-03 0,02337034 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 4,177E-03 0,02331611 ! Schwann cell development GO:0014044 15 6 0,000 4,177E-03 0,02326214 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 4,177E-03 0,02320842 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 4,177E-03 0,02315494 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 4,177E-03 0,02310171 ! subpallium development GO:0021544 10 6 0,000 4,177E-03 0,02304873 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 4,177E-03 0,02299598 ! histone ubiquitination GO:0016574 8 6 0,000 4,177E-03 0,02294348 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 4,177E-03 0,02289122 ! maintenance of organ identity GO:0048496 9 6 0,000 4,177E-03 0,02283919 ! G2 phase GO:0051319 16 6 0,000 4,177E-03 0,0227874 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 4,177E-03 0,02273585 ! establishment of planar polarity GO:0001736 7 6 0,000 4,177E-03 0,02268453 ! regulation of mast cell activation GO:0033003 12 6 0,000 4,177E-03 0,02263343 ! membrane to membrane docking GO:0022614 14 6 0,000 4,177E-03 0,02258257 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 4,177E-03 0,02253194 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 4,177E-03 0,02248153 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 4,177E-03 0,02243135 ! receptor internalization GO:0031623 10 6 0,000 4,177E-03 0,02238139 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 4,177E-03 0,02233166 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 4,177E-03 0,02228214 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 4,177E-03 0,02223284 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 4,177E-03 0,02218376 ! protein deubiquitination GO:0016579 14 6 0,000 4,177E-03 0,0221349 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 4,177E-03 0,02208625 ! protein destabilization GO:0031648 9 6 0,000 4,177E-03 0,02203782 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 4,177E-03 0,0219896 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 4,177E-03 0,02194158 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 4,177E-03 0,02189378 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 4,177E-03 0,02184618 ! progesterone metabolic process GO:0042448 10 6 0,000 4,177E-03 0,0217988 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 4,177E-03 0,02175161 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 4,177E-03 0,02170463 ! negative regulation of axon extension GO:0030517 21 6 0,000 4,177E-03 0,02165786 ! removal of superoxide radicals GO:0019430 11 6 0,000 4,177E-03 0,02161128 ! triglyceride catabolic process GO:0019433 10 6 0,000 4,177E-03 0,0215649 ! determination of adult lifespan GO:0008340 15 6 0,000 4,177E-03 0,02151873 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 4,177E-03 0,02147275 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 4,177E-03 0,02142696 ! cerebellar cortex formation GO:0021697 8 6 0,000 4,177E-03 0,02138137 ! catecholamine transport GO:0051937 9 6 0,000 4,177E-03 0,02133598 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 4,177E-03 0,02129077 ! sensory cilium assembly GO:0035058 10 6 0,000 4,177E-03 0,02124576 ! organ or tissue specific immune response GO:0002251 7 6 0,000 4,177E-03 0,02120094 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 4,177E-03 0,02115631 ! maternal placenta development GO:0001893 12 6 0,000 4,177E-03 0,02111186 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 4,177E-03 0,0210676 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 4,177E-03 0,02102352 ! negative regulation of B cell activation GO:0050869 13 6 0,000 4,177E-03 0,02097963 ! protein amino acid prenylation GO:0018346 16 6 0,000 4,177E-03 0,02093593 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 4,177E-03 0,0208924 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 4,177E-03 0,02084906 ! positive regulation of coagulation GO:0050820 12 6 0,000 4,177E-03 0,02080589 ! tRNA transcription GO:0009304 14 7 0,000 4,871E-03 0,02421535 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 4,871E-03 0,02416542 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 4,871E-03 0,0241157 ! behavioral response to cocaine GO:0048148 14 7 0,000 4,871E-03 0,02406618 ! regulation of helicase activity GO:0051095 15 7 0,000 4,871E-03 0,02401686 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 4,871E-03 0,02396775 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 4,871E-03 0,02391883 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 4,871E-03 0,02387012 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 4,871E-03 0,0238216 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 4,871E-03 0,02377328 ! prostate gland development GO:0030850 13 7 0,000 4,871E-03 0,02372516 ! nucleotide-sugar transport GO:0015780 12 7 0,000 4,871E-03 0,02367723 ! synaptonemal complex assembly GO:0007130 10 7 0,000 4,871E-03 0,02362949 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 4,871E-03 0,02358195 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 4,871E-03 0,02353459 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 4,871E-03 0,02348743 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 4,871E-03 0,02344046 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 4,871E-03 0,02339367 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 4,871E-03 0,02334707 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 4,871E-03 0,02330065 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 4,871E-03 0,02325442 ! SMAD protein complex assembly GO:0007183 12 7 0,000 4,871E-03 0,02320837 ! glycolipid transport GO:0046836 10 7 0,000 4,871E-03 0,02316251 ! protein amino acid sulfation GO:0006477 10 7 0,000 4,871E-03 0,02311682 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 4,871E-03 0,02307131 ! neuron adhesion GO:0007158 12 7 0,000 4,871E-03 0,02302599 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 4,871E-03 0,02298084 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 4,871E-03 0,02293587 ! actin-myosin filament sliding GO:0033275 11 7 0,000 4,871E-03 0,02289107 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 4,871E-03 0,02284645 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 4,871E-03 0,022802 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 4,871E-03 0,02275772 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 4,871E-03 0,02271362 ! mRNA stabilization GO:0048255 18 7 0,000 4,871E-03 0,02266969 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 4,871E-03 0,02262592 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 4,871E-03 0,02258233 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 4,871E-03 0,0225389 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 4,871E-03 0,02249564 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 4,871E-03 0,02245254 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 4,871E-03 0,02240961 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 4,871E-03 0,02236685 ! lipoprotein transport GO:0042953 14 7 0,000 4,871E-03 0,02232424 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 4,871E-03 0,0222818 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 4,871E-03 0,02223952 ! rhythmic behavior GO:0007622 15 7 0,000 4,871E-03 0,0221974 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 4,871E-03 0,02215544 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 4,871E-03 0,02211364 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 4,871E-03 0,02207199 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 4,871E-03 0,0220305 ! regulation of odontogenesis GO:0042481 13 7 0,000 4,871E-03 0,02198917 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 4,871E-03 0,02194799 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 4,871E-03 0,02190697 ! mechanosensory behavior GO:0007638 14 7 0,000 4,871E-03 0,0218661 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 4,871E-03 0,02182538 ! positive regulation of isotype switching GO:0045830 15 7 0,000 4,871E-03 0,02178481 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 4,871E-03 0,02174439 ! protein-cofactor linkage GO:0018065 13 7 0,000 4,871E-03 0,02170413 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 4,871E-03 0,02166401 ! spinal cord patterning GO:0021511 13 7 0,000 4,871E-03 0,02162404 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 4,871E-03 0,02158421 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 4,871E-03 0,02154454 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 4,871E-03 0,02150501 ! adrenal gland development GO:0030325 17 7 0,000 4,871E-03 0,02146562 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 4,871E-03 0,02142638 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 4,871E-03 0,02138728 ! ovulation GO:0030728 9 7 0,000 4,871E-03 0,02134832 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 4,871E-03 0,02130951 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 4,871E-03 0,02127083 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 4,871E-03 0,0212323 ! microtubule nucleation GO:0007020 20 7 0,000 4,871E-03 0,0211939 ! proline biosynthetic process GO:0006561 10 7 0,000 4,871E-03 0,02115565 ! thyroid hormone generation GO:0006590 13 7 0,000 4,871E-03 0,02111753 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 4,871E-03 0,02107955 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 4,871E-03 0,0210417 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 4,871E-03 0,02100399 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 4,871E-03 0,02096642 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 4,871E-03 0,02092898 ! galactose metabolic process GO:0006012 13 7 0,000 4,871E-03 0,02089167 ! vesicle fusion GO:0006906 17 7 0,000 4,871E-03 0,0208545 ! response to dietary excess GO:0002021 8 7 0,000 4,871E-03 0,02081746 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 4,871E-03 0,02078055 ! intracellular pH reduction GO:0051452 11 7 0,000 4,871E-03 0,02074377 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 4,871E-03 0,02070712 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 4,871E-03 0,0206706 ! organ growth GO:0035265 15 7 0,000 4,871E-03 0,0206342 ! purine salvage GO:0043101 10 7 0,000 4,871E-03 0,02059794 ! nucleoside transport GO:0015858 8 7 0,000 4,871E-03 0,0205618 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 4,871E-03 0,02052579 ! parturition GO:0007567 14 7 0,000 4,871E-03 0,02048991 ! rRNA modification GO:0000154 14 7 0,000 4,871E-03 0,02045415 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 4,871E-03 0,02041852 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 4,871E-03 0,020383 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 4,871E-03 0,02034762 ! macrophage differentiation GO:0030225 11 7 0,000 4,871E-03 0,02031235 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 4,871E-03 0,02027721 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 4,871E-03 0,02024219 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 4,871E-03 0,02020729 ! hyaluronan metabolic process GO:0030212 8 7 0,000 4,871E-03 0,02017251 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 4,871E-03 0,02013785 ! anterograde axon cargo transport GO:0008089 18 7 0,000 4,871E-03 0,02010331 ! fibrinolysis GO:0042730 10 7 0,000 4,871E-03 0,02006888 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 4,871E-03 0,02003458 ! eating behavior GO:0042755 7 7 0,000 4,871E-03 0,02000039 ! B cell lineage commitment GO:0002326 21 7 0,000 4,871E-03 0,01996632 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 4,871E-03 0,01993236 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 4,871E-03 0,01989852 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 4,871E-03 0,01986479 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 4,871E-03 0,01983118 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 4,871E-03 0,01979768 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 4,871E-03 0,0197643 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 4,871E-03 0,01973102 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 4,871E-03 0,01969786 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 4,871E-03 0,01966481 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 4,871E-03 0,01963187 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 4,871E-03 0,01959904 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 4,871E-03 0,01956632 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 4,871E-03 0,01953371 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 4,871E-03 0,01950121 ! regulation of meiosis GO:0040020 12 7 0,000 4,871E-03 0,01946882 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 4,871E-03 0,01943653 ! T cell lineage commitment GO:0002360 16 7 0,000 4,871E-03 0,01940435 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 4,871E-03 0,01937228 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 4,871E-03 0,01934031 ! oxygen homeostasis GO:0032364 12 7 0,000 4,871E-03 0,01930845 ! transcription termination GO:0006353 13 7 0,000 4,871E-03 0,01927669 ! response to tumor cell GO:0002347 13 7 0,000 4,871E-03 0,01924504 ! regulation of respiratory burst GO:0060263 11 7 0,000 4,871E-03 0,01921349 ! coenzyme A metabolic process GO:0015936 12 7 0,000 4,871E-03 0,01918204 ! anaphase GO:0051322 17 7 0,000 4,871E-03 0,0191507 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 4,871E-03 0,01911946 ! axonal fasciculation GO:0007413 18 7 0,000 4,871E-03 0,01908832 ! negative regulation of nuclear division GO:0051784 14 7 0,000 4,871E-03 0,01905728 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 4,871E-03 0,01902634 ! peptidyl-threonine modification GO:0018210 25 7 0,000 4,871E-03 0,01899551 ! diuresis GO:0030146 12 7 0,000 4,871E-03 0,01896477 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 4,871E-03 0,01893413 ! thiamin metabolic process GO:0006772 7 7 0,000 4,871E-03 0,01890359 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 4,871E-03 0,01887315 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 4,871E-03 0,01884281 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 4,871E-03 0,01881256 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 4,871E-03 0,01878242 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 4,871E-03 0,01875236 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 4,871E-03 0,01872241 ! melanin biosynthetic process GO:0042438 8 7 0,000 4,871E-03 0,01869255 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 4,871E-03 0,01866278 ! dopamine biosynthetic process GO:0042416 18 7 0,000 4,871E-03 0,01863311 ! glycolipid catabolic process GO:0019377 15 7 0,000 4,871E-03 0,01860354 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 4,871E-03 0,01857405 ! lymph node development GO:0048535 10 7 0,000 4,871E-03 0,01854466 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 4,871E-03 0,01851537 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 4,871E-03 0,01848616 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 4,871E-03 0,01845705 ! endosome to lysosome transport GO:0008333 11 7 0,000 4,871E-03 0,01842803 ! protein modification by small protein removal GO:0070646 16 7 0,000 4,871E-03 0,0183991 ! adult feeding behavior GO:0008343 9 7 0,000 4,871E-03 0,01837026 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 4,871E-03 0,01834151 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 4,871E-03 0,01831286 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 4,871E-03 0,01828429 ! muscle adaptation GO:0043500 14 7 0,000 4,871E-03 0,01825581 ! embryonic heart tube development GO:0035050 10 7 0,000 4,871E-03 0,01822741 ! retina homeostasis GO:0001895 12 7 0,000 4,871E-03 0,01819911 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 4,871E-03 0,0181709 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 4,871E-03 0,01814277 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 4,871E-03 0,01811473 ! protein prenylation GO:0018342 18 7 0,000 4,871E-03 0,01808677 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 4,871E-03 0,0180589 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 4,871E-03 0,01803112 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 4,871E-03 0,01800342 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 5,565E-03 0,02053696 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 5,565E-03 0,02050551 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 5,565E-03 0,02047416 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 5,565E-03 0,0204429 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 5,565E-03 0,02041174 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 5,565E-03 0,02038067 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 5,565E-03 0,0203497 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 5,565E-03 0,02031882 ! neutral lipid catabolic process GO:0046461 13 8 0,000 5,565E-03 0,02028803 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 5,565E-03 0,02025734 ! meiotic prophase I GO:0007128 13 8 0,000 5,565E-03 0,02022674 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 5,565E-03 0,02019623 ! oligopeptide transport GO:0006857 15 8 0,000 5,565E-03 0,02016581 ! UTP metabolic process GO:0046051 8 8 0,000 5,565E-03 0,02013549 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 5,565E-03 0,02010526 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 5,565E-03 0,02007511 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 5,565E-03 0,02004506 ! macrophage chemotaxis GO:0048246 12 8 0,000 5,565E-03 0,0200151 ! succinate metabolic process GO:0006105 14 8 0,000 5,565E-03 0,01998523 ! membrane hyperpolarization GO:0060081 10 8 0,000 5,565E-03 0,01995544 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 5,565E-03 0,01992575 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 5,565E-03 0,01989614 ! T-helper 1 type immune response GO:0042088 12 8 0,000 5,565E-03 0,01986662 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 5,565E-03 0,01983719 GO:0032107|regulation of response to nutrient levels, ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 5,565E-03 0,01980784 ! ganglioside metabolic process GO:0001573 19 8 0,000 5,565E-03 0,01977858 ! reflex GO:0060004 16 8 0,000 5,565E-03 0,01974941 ! negative regulation of endocytosis GO:0045806 11 8 0,000 5,565E-03 0,01972033 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 5,565E-03 0,01969132 ! endothelial cell differentiation GO:0045446 17 8 0,000 5,565E-03 0,01966241 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 5,565E-03 0,01963358 ! glycerolipid catabolic process GO:0046503 13 8 0,000 5,565E-03 0,01960483 ! hemoglobin metabolic process GO:0020027 13 8 0,000 5,565E-03 0,01957617 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 5,565E-03 0,01954759 ! pigment granule organization GO:0048753 16 8 0,000 5,565E-03 0,0195191 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 5,565E-03 0,01949069 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 5,565E-03 0,01946236 ! astrocyte differentiation GO:0048708 18 8 0,000 5,565E-03 0,01943411 ! histidine metabolic process GO:0006547 16 8 0,000 5,565E-03 0,01940594 GO:0009075|histidine family amino acid metabolic process, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 5,565E-03 0,01937786 ! glycine catabolic process GO:0006546 13 8 0,000 5,565E-03 0,01934986 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 5,565E-03 0,01932193 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 5,565E-03 0,01929409 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 5,565E-03 0,01926633 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 5,565E-03 0,01923865 ! regulation of pigmentation during development GO:0048070 24 8 0,000 5,565E-03 0,01921105 ! melanin metabolic process GO:0006582 15 8 0,000 5,565E-03 0,01918353 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 5,565E-03 0,01915608 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 5,565E-03 0,01912872 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 5,565E-03 0,01910143 ! macrophage activation GO:0042116 12 8 0,000 5,565E-03 0,01907422 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 5,565E-03 0,01904709 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 5,565E-03 0,01902003 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 5,565E-03 0,01899305 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 5,565E-03 0,01896615 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 5,565E-03 0,01893932 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 5,565E-03 0,01891257 ! regulation of vascular permeability GO:0043114 12 8 0,000 5,565E-03 0,0188859 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 5,565E-03 0,0188593 ! osteoblast development GO:0002076 16 8 0,000 5,565E-03 0,01883277 ! positive regulation of vasodilation GO:0045909 13 8 0,000 5,565E-03 0,01880632 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 5,565E-03 0,01877995 ! negative regulation of translational initiation GO:0045947 10 8 0,000 5,565E-03 0,01875364 ! Schwann cell differentiation GO:0014037 19 8 0,000 5,565E-03 0,01872741 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 5,565E-03 0,01870126 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 5,565E-03 0,01867518 ! response to UV-B GO:0010224 16 8 0,000 5,565E-03 0,01864917 ! protein targeting to vacuole GO:0006623 12 8 0,000 5,565E-03 0,01862323 ! protein retention in ER lumen GO:0006621 14 8 0,000 5,565E-03 0,01859736 ! intermediate filament organization GO:0045109 12 8 0,000 5,565E-03 0,01857157 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 5,565E-03 0,01854585 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 5,565E-03 0,01852019 ! cellular extravasation GO:0045123 12 8 0,000 5,565E-03 0,01849461 ! cardiac muscle cell development GO:0055013 13 8 0,000 5,565E-03 0,0184691 ! regulation of circadian rhythm GO:0042752 16 8 0,000 5,565E-03 0,01844366 ! response to antibiotic GO:0046677 11 8 0,000 5,565E-03 0,0184183 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 5,565E-03 0,018393 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 5,565E-03 0,01836777 ! DNA topological change GO:0006265 12 8 0,000 5,565E-03 0,0183426 ! response to tropane GO:0014073 15 8 0,000 5,565E-03 0,01831751 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 5,565E-03 0,01829249 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 5,565E-03 0,01826753 ! melanosome transport GO:0032402 13 8 0,000 5,565E-03 0,01824264 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 0,000 5,565E-03 0,01821782 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 5,565E-03 0,01819307 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 5,565E-03 0,01816839 ! mast cell activation GO:0045576 14 8 0,000 5,565E-03 0,01814377 ! multicellular organismal aging GO:0010259 18 8 0,000 5,565E-03 0,01811922 ! dendrite morphogenesis GO:0048813 13 8 0,000 5,565E-03 0,01809473 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 5,565E-03 0,01807031 ! nucleosome disassembly GO:0006337 14 8 0,000 5,565E-03 0,01804596 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 5,565E-03 0,01802167 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 5,565E-03 0,01799745 ! leukocyte activation during immune response GO:0002366 13 8 0,000 5,565E-03 0,01797329 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 5,565E-03 0,0179492 ! mitochondrion morphogenesis GO:0070584 14 8 0,000 5,565E-03 0,01792517 ! intracellular lipid transport GO:0032365 13 8 0,000 5,565E-03 0,0179012 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 5,565E-03 0,0178773 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 5,565E-03 0,01785347 ! regulation of macrophage activation GO:0043030 15 8 0,000 5,565E-03 0,01782969 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 5,565E-03 0,01780599 ! positive regulation of epidermis development GO:0045684 13 8 0,000 5,565E-03 0,01778234 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 5,565E-03 0,01775875 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 5,565E-03 0,01773523 ! hormone catabolic process GO:0042447 17 8 0,000 5,565E-03 0,01771177 ! positive regulation of glucose import GO:0046326 8 8 0,000 5,565E-03 0,01768838 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 5,565E-03 0,01766504 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 5,565E-03 0,01764177 ! ATP catabolic process GO:0006200 11 8 0,000 5,565E-03 0,01761855 ! blastocyst growth GO:0001832 19 8 0,000 5,565E-03 0,0175954 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 5,565E-03 0,01757231 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 5,565E-03 0,01754928 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 5,565E-03 0,01752631 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 5,565E-03 0,0175034 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 5,565E-03 0,01748055 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 5,565E-03 0,01745776 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 5,565E-03 0,01743503 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 5,565E-03 0,01741235 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 5,565E-03 0,01738974 ! amino sugar catabolic process GO:0046348 10 8 0,000 5,565E-03 0,01736719 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 5,565E-03 0,01734469 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 5,565E-03 0,01732225 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 5,565E-03 0,01729987 ! behavioral response to nicotine GO:0035095 12 8 0,000 5,565E-03 0,01727755 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 5,565E-03 0,01725528 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 5,565E-03 0,01723308 ! NAD biosynthetic process GO:0009435 13 8 0,000 5,565E-03 0,01721093 ! regulation of developmental growth GO:0048638 15 9 0,000 6,259E-03 0,01933102 ! axon extension GO:0048675 15 9 0,000 6,259E-03 0,01930624 ! autophagic vacuole formation GO:0000045 15 9 0,000 6,259E-03 0,01928152 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 6,259E-03 0,01925686 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 6,259E-03 0,01923227 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 6,259E-03 0,01920774 ! pentose-phosphate shunt GO:0006098 16 9 0,000 6,259E-03 0,01918327 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 6,259E-03 0,01915886 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 6,259E-03 0,01913452 ! cell proliferation in forebrain GO:0021846 15 9 0,000 6,259E-03 0,01911023 ! phosphate transport GO:0006817 19 9 0,000 6,259E-03 0,01908601 ! reproductive behavior GO:0019098 19 9 0,000 6,259E-03 0,01906185 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 6,259E-03 0,01903776 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 6,259E-03 0,01901372 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 6,259E-03 0,01898974 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 6,259E-03 0,01896582 ! GTP metabolic process GO:0046039 9 9 0,000 6,259E-03 0,01894197 ! RNA methylation GO:0001510 15 9 0,000 6,259E-03 0,01891817 ! elastic fiber assembly GO:0048251 15 9 0,000 6,259E-03 0,01889443 ! induction of positive chemotaxis GO:0050930 15 9 0,000 6,259E-03 0,01887076 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 6,259E-03 0,01884714 ! artery development GO:0060840 24 9 0,000 6,259E-03 0,01882358 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 6,259E-03 0,01880008 ! regulation of glycolysis GO:0006110 21 9 0,000 6,259E-03 0,01877664 ! cerebral cortex cell migration GO:0021795 15 9 0,000 6,259E-03 0,01875326 ! keratinocyte proliferation GO:0043616 14 9 0,000 6,259E-03 0,01872993 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 6,259E-03 0,01870666 ! chemosensory behavior GO:0007635 20 9 0,000 6,259E-03 0,01868345 ! microtubule bundle formation GO:0001578 21 9 0,000 6,259E-03 0,0186603 ! middle ear morphogenesis GO:0042474 14 9 0,000 6,259E-03 0,01863721 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 6,259E-03 0,01861417 ! leukocyte degranulation GO:0043299 16 9 0,000 6,259E-03 0,01859119 ! bile acid and bile salt transport GO:0015721 13 9 0,000 6,259E-03 0,01856827 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 6,259E-03 0,0185454 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 6,259E-03 0,01852259 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 6,259E-03 0,01849983 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 6,259E-03 0,01847713 ! protein targeting to ER GO:0045047 22 9 0,000 6,259E-03 0,01845449 ! ceramide biosynthetic process GO:0046513 19 9 0,000 6,259E-03 0,0184319 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 6,259E-03 0,01840937 ! T cell selection GO:0045058 23 9 0,000 6,259E-03 0,01838689 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 6,259E-03 0,01836447 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 6,259E-03 0,0183421 ! phosphagen metabolic process GO:0006599 12 9 0,000 6,259E-03 0,01831979 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 6,259E-03 0,01829753 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 6,259E-03 0,01827532 ! regulation of type I interferon production GO:0032479 12 9 0,000 6,259E-03 0,01825317 ! mannose metabolic process GO:0006013 13 9 0,000 6,259E-03 0,01823107 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 6,259E-03 0,01820903 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 6,259E-03 0,01818703 ! Rac protein signal transduction GO:0016601 17 9 0,000 6,259E-03 0,0181651 ! receptor clustering GO:0043113 18 9 0,000 6,259E-03 0,01814321 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 6,259E-03 0,01812138 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 6,259E-03 0,0180996 ! ruffle organization GO:0031529 15 9 0,000 6,259E-03 0,01807787 ! retinol metabolic process GO:0042572 18 9 0,000 6,259E-03 0,01805619 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 6,259E-03 0,01803457 ! behavioral fear response GO:0001662 22 9 0,000 6,259E-03 0,018013 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 6,259E-03 0,01799147 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 6,259E-03 0,01797001 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 6,259E-03 0,01794859 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 6,259E-03 0,01792722 ! protein heterooligomerization GO:0051291 16 9 0,000 6,259E-03 0,0179059 ! oligodendrocyte development GO:0014003 10 9 0,000 6,259E-03 0,01788464 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 6,259E-03 0,01786342 ! segment specification GO:0007379 13 9 0,000 6,259E-03 0,01784226 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 6,259E-03 0,01782114 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 6,259E-03 0,01780008 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 6,259E-03 0,01777906 ! response to amine stimulus GO:0014075 13 9 0,000 6,259E-03 0,01775809 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 6,259E-03 0,01773718 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 6,259E-03 0,01771631 ! erythrocyte development GO:0048821 15 9 0,000 6,259E-03 0,01769549 ! gas homeostasis GO:0033483 16 9 0,000 6,259E-03 0,01767472 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 6,259E-03 0,017654 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 6,259E-03 0,01763333 ! renal water homeostasis GO:0003091 14 9 0,000 6,259E-03 0,01761271 ! postreplication repair GO:0006301 22 9 0,000 6,259E-03 0,01759213 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 6,259E-03 0,0175716 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 6,259E-03 0,01755112 ! icosanoid secretion GO:0032309 15 9 0,000 6,259E-03 0,01753069 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 6,259E-03 0,01751031 ! cerebellum morphogenesis GO:0021587 14 9 0,000 6,259E-03 0,01748997 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 6,259E-03 0,01746968 ! regulation of cell division GO:0051302 15 9 0,000 6,259E-03 0,01744944 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 6,259E-03 0,01742924 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 6,259E-03 0,01740909 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 6,259E-03 0,01738899 ! sterol catabolic process GO:0016127 11 9 0,000 6,259E-03 0,01736893 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 6,259E-03 0,01734892 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 6,259E-03 0,01732896 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 6,259E-03 0,01730904 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 6,259E-03 0,01728917 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 6,259E-03 0,01726934 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 6,259E-03 0,01724956 ! musculoskeletal movement GO:0050881 14 9 0,000 6,259E-03 0,01722982 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 6,259E-03 0,01721013 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 6,259E-03 0,01719048 ! regulation of synaptogenesis GO:0051963 15 9 0,000 6,259E-03 0,01717088 ! purine base metabolic process GO:0006144 21 9 0,000 6,259E-03 0,01715133 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 6,259E-03 0,01713181 ! pigment granule transport GO:0051904 17 9 0,000 6,259E-03 0,01711235 ! regulation of fibrinolysis GO:0051917 16 9 0,000 6,259E-03 0,01709292 ! regulation of telomere maintenance GO:0032204 14 9 0,000 6,259E-03 0,01707354 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 6,259E-03 0,01705421 ! regulation of muscle adaptation GO:0043502 14 9 0,000 6,259E-03 0,01703491 ! regulation of amino acid transport GO:0051955 11 9 0,000 6,259E-03 0,01701567 ! mitochondrion localization GO:0051646 15 9 0,000 6,259E-03 0,01699646 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 6,952E-03 0,01885741 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 6,952E-03 0,01883617 ! negative regulation of blood pressure GO:0045776 26 10 0,000 6,952E-03 0,01881498 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 6,952E-03 0,01879384 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 6,952E-03 0,01877275 ! synapsis GO:0007129 13 10 0,000 6,952E-03 0,0187517 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 6,952E-03 0,01873071 ! N-glycan processing GO:0006491 20 10 0,000 6,952E-03 0,01870975 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 6,952E-03 0,01868885 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 6,952E-03 0,01866799 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 6,952E-03 0,01864718 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 6,952E-03 0,01862641 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 6,952E-03 0,01860569 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 6,952E-03 0,01858502 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 6,952E-03 0,01856439 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 6,952E-03 0,01854381 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 6,952E-03 0,01852328 ! androgen metabolic process GO:0008209 17 10 0,000 6,952E-03 0,01850279 ! phospholipid efflux GO:0033700 16 10 0,000 6,952E-03 0,01848234 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 6,952E-03 0,01846194 ! positive regulation of heart contraction GO:0045823 16 10 0,000 6,952E-03 0,01844159 ! lung alveolus development GO:0048286 26 10 0,000 6,952E-03 0,01842128 ! pathogenesis GO:0009405 13 10 0,000 6,952E-03 0,01840101 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 6,952E-03 0,01838079 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 6,952E-03 0,01836061 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 6,952E-03 0,01834048 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 6,952E-03 0,01832039 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 6,952E-03 0,01830035 ! endoderm development GO:0007492 16 10 0,000 6,952E-03 0,01828035 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 6,952E-03 0,01826039 ! arginine catabolic process GO:0006527 13 10 0,000 6,952E-03 0,01824048 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 6,952E-03 0,01822061 ! proline metabolic process GO:0006560 13 10 0,000 6,952E-03 0,01820078 ! glucan biosynthetic process GO:0009250 14 10 0,000 6,952E-03 0,018181 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 6,952E-03 0,01816126 ! polyamine biosynthetic process GO:0006596 12 10 0,000 6,952E-03 0,01814156 ! V(D)J recombination GO:0033151 28 10 0,000 6,952E-03 0,01812191 ! reverse cholesterol transport GO:0043691 16 10 0,000 6,952E-03 0,01810229 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 6,952E-03 0,01808272 GO:0021952|central nervous system projection neuron axonogenesis, ! B cell proliferation GO:0042100 18 10 0,000 6,952E-03 0,0180632 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 6,952E-03 0,01804371 ! regulation of sodium ion transport GO:0002028 21 10 0,000 6,952E-03 0,01802427 ! multicellular organism growth GO:0035264 18 10 0,000 6,952E-03 0,01800487 ! phagocytosis, engulfment GO:0006911 28 10 0,000 6,952E-03 0,01798551 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 6,952E-03 0,01796619 ! epithelial cell development GO:0002064 20 10 0,000 6,952E-03 0,01794691 ! lens development in camera-type eye GO:0002088 16 10 0,000 6,952E-03 0,01792767 ! retinoic acid metabolic process GO:0042573 14 10 0,000 6,952E-03 0,01790848 ! macroautophagy GO:0016236 17 10 0,000 6,952E-03 0,01788933 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 6,952E-03 0,01787021 ! positive regulation of translational initiation GO:0045948 11 10 0,000 6,952E-03 0,01785114 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 6,952E-03 0,01783211 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 6,952E-03 0,01781312 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 6,952E-03 0,01779417 ! copper ion homeostasis GO:0055070 13 10 0,000 6,952E-03 0,01777526 ! regulation of bone resorption GO:0045124 25 10 0,000 6,952E-03 0,01775639 ! regulation of gliogenesis GO:0014013 23 10 0,000 6,952E-03 0,01773756 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 6,952E-03 0,01771877 ! alpha-beta T cell activation GO:0046631 23 10 0,000 6,952E-03 0,01770002 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 6,952E-03 0,01768131 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 6,952E-03 0,01766264 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 6,952E-03 0,01764401 ! blastoderm segmentation GO:0007350 18 10 0,000 6,952E-03 0,01762542 ! response to dsRNA GO:0043331 20 10 0,000 6,952E-03 0,01760686 ! DNA ligation GO:0006266 19 10 0,000 6,952E-03 0,01758835 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 6,952E-03 0,01756987 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 6,952E-03 0,01755144 ! melanosome localization GO:0032400 16 10 0,000 6,952E-03 0,01753304 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 6,952E-03 0,01751468 ! regulation of B cell differentiation GO:0045577 19 10 0,000 6,952E-03 0,01749636 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 6,952E-03 0,01747808 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 6,952E-03 0,01745983 ! mRNA cleavage GO:0006379 17 10 0,000 6,952E-03 0,01744163 ! protein sumoylation GO:0016925 15 10 0,000 6,952E-03 0,01742346 ! hindbrain morphogenesis GO:0021575 19 10 0,000 6,952E-03 0,01740533 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 6,952E-03 0,01738723 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 6,952E-03 0,01736918 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 6,952E-03 0,01735116 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 6,952E-03 0,01733318 ! salivary gland development GO:0007431 27 10 0,000 6,952E-03 0,01731524 ! prophase GO:0051324 15 10 0,000 6,952E-03 0,01729733 ! negative regulation of neurological system process GO:0031645 19 10 0,000 6,952E-03 0,01727946 ! apical protein localization GO:0045176 15 10 0,000 6,952E-03 0,01726163 ! ubiquinone metabolic process GO:0006743 15 10 0,000 6,952E-03 0,01724383 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 6,952E-03 0,01722608 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 6,952E-03 0,01720835 ! midbrain development GO:0030901 13 10 0,000 6,952E-03 0,01719067 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 6,952E-03 0,01717302 ! methionine biosynthetic process GO:0009086 19 10 0,000 6,952E-03 0,0171554 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 6,952E-03 0,01713783 ! quaternary ammonium group transport GO:0015697 21 10 0,000 6,952E-03 0,01712029 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 6,952E-03 0,01710278 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 6,952E-03 0,01708531 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 6,952E-03 0,01706788 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 6,952E-03 0,01705048 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 6,952E-03 0,01703312 ! oocyte development GO:0048599 17 10 0,000 6,952E-03 0,01701579 ! establishment of pigment granule localization GO:0051905 18 10 0,000 6,952E-03 0,0169985 ! blastocyst formation GO:0001825 17 10 0,000 6,952E-03 0,01698124 ! cerebellar cortex development GO:0021695 15 10 0,000 6,952E-03 0,01696402 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 6,952E-03 0,01694683 ! activation of innate immune response GO:0002218 12 10 0,000 6,952E-03 0,01692968 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 6,952E-03 0,01691256 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 6,952E-03 0,01689547 ! response to nicotine GO:0035094 20 10 0,000 6,952E-03 0,01687843 ! establishment of cell polarity GO:0030010 16 10 0,000 6,952E-03 0,01686141 ! negative regulation of immune effector process GO:0002698 20 10 0,000 6,952E-03 0,01684443 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 6,952E-03 0,01682748 ! localization within membrane GO:0051668 20 10 0,000 6,952E-03 0,01681057 ! negative regulation of muscle development GO:0048635 20 11 0,000 7,645E-03 0,01846693 ! respiratory burst GO:0045730 17 11 0,000 7,645E-03 0,01844841 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 7,645E-03 0,01842993 ! neuron fate specification GO:0048665 17 11 0,000 7,645E-03 0,01841148 ! telencephalon cell migration GO:0022029 20 11 0,000 7,645E-03 0,01839307 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 7,645E-03 0,01837469 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 7,645E-03 0,01835635 ! thyroid gland development GO:0030878 26 11 0,000 7,645E-03 0,01833805 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 7,645E-03 0,01831979 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 7,645E-03 0,01830156 ! Golgi vesicle budding GO:0048194 22 11 0,000 7,645E-03 0,01828337 ! response to pain GO:0048265 24 11 0,000 7,645E-03 0,01826521 ! detection of mechanical stimulus GO:0050982 22 11 0,000 7,645E-03 0,01824709 ! T cell proliferation GO:0042098 26 11 0,000 7,645E-03 0,01822901 ! blood vessel remodeling GO:0001974 29 11 0,000 7,645E-03 0,01821096 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 7,645E-03 0,01819294 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 7,645E-03 0,01817497 ! bone resorption GO:0045453 16 11 0,000 7,645E-03 0,01815703 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 7,645E-03 0,01813912 ! ventral spinal cord development GO:0021517 21 11 0,000 7,645E-03 0,01812125 ! negative regulation of proteolysis GO:0045861 25 11 0,000 7,645E-03 0,01810341 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 7,645E-03 0,01808561 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 7,645E-03 0,01806785 ! melanocyte differentiation GO:0030318 21 11 0,000 7,645E-03 0,01805012 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 7,645E-03 0,01803242 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 7,645E-03 0,01801476 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 7,645E-03 0,01799713 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 7,645E-03 0,01797954 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 7,645E-03 0,01796198 ! lipid digestion GO:0044241 18 11 0,000 7,645E-03 0,01794446 ! substrate-bound cell migration GO:0006929 13 11 0,000 7,645E-03 0,01792697 ! UV protection GO:0009650 19 11 0,000 7,645E-03 0,01790951 ! adult heart development GO:0007512 14 11 0,000 7,645E-03 0,01789209 ! chondrocyte differentiation GO:0002062 24 11 0,000 7,645E-03 0,0178747 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 7,645E-03 0,01785735 ! temperature homeostasis GO:0001659 17 11 0,000 7,645E-03 0,01784003 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 7,645E-03 0,01782274 ! negative regulation of ossification GO:0030279 26 11 0,000 7,645E-03 0,01780549 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 7,645E-03 0,01778827 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 7,645E-03 0,01777108 ! regulation of organ growth GO:0046620 13 11 0,000 7,645E-03 0,01775393 ! pigment granule localization GO:0051875 20 11 0,000 7,645E-03 0,01773681 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 7,645E-03 0,01771972 ! vasoconstriction GO:0042310 18 11 0,000 7,645E-03 0,01770266 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 7,645E-03 0,01768564 ! embryonic axis specification GO:0000578 18 11 0,000 7,645E-03 0,01766865 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 7,645E-03 0,0176517 ! snRNA metabolic process GO:0016073 24 11 0,000 7,645E-03 0,01763477 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 7,645E-03 0,01761788 ! nitric oxide metabolic process GO:0046209 15 11 0,000 7,645E-03 0,01760102 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 7,645E-03 0,01758419 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 7,645E-03 0,0175674 ! zymogen activation GO:0031638 15 11 0,000 7,645E-03 0,01755064 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 7,645E-03 0,01753391 ! neuroblast proliferation GO:0007405 24 11 0,000 7,645E-03 0,01751721 ! nucleosome positioning GO:0016584 15 11 0,000 7,645E-03 0,01750054 ! regulation of isotype switching GO:0045191 22 11 0,000 7,645E-03 0,0174839 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 7,645E-03 0,0174673 ! glutathione biosynthetic process GO:0006750 13 11 0,000 7,645E-03 0,01745073 ! regulation of leukocyte migration GO:0002685 26 11 0,000 7,645E-03 0,01743419 ! acid secretion GO:0046717 18 11 0,000 7,645E-03 0,01741768 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 7,645E-03 0,0174012 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 7,645E-03 0,01738475 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 7,645E-03 0,01736834 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 7,645E-03 0,01735195 ! oocyte differentiation GO:0009994 18 11 0,000 7,645E-03 0,0173356 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 7,645E-03 0,01731927 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 7,645E-03 0,01730298 ! cholesterol efflux GO:0033344 19 11 0,000 7,645E-03 0,01728672 ! anterior/posterior axis specification GO:0009948 18 11 0,000 7,645E-03 0,01727049 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 7,645E-03 0,01725428 ! negative regulation of glucose import GO:0046325 17 11 0,000 7,645E-03 0,01723811 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 7,645E-03 0,01722197 ! embryonic gut development GO:0048566 15 11 0,000 7,645E-03 0,01720586 ! regulation of organic acid transport GO:0032890 18 11 0,000 7,645E-03 0,01718978 ! cardiac cell differentiation GO:0035051 31 11 0,000 7,645E-03 0,01717373 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 7,645E-03 0,01715771 ! defense response to fungus GO:0050832 13 11 0,000 7,645E-03 0,01714172 ! developmental induction GO:0031128 19 11 0,000 7,645E-03 0,01712576 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 7,645E-03 0,01710983 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 7,645E-03 0,01709393 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 7,645E-03 0,01707806 ! sequestering of metal ion GO:0051238 14 11 0,000 7,645E-03 0,01706221 ! lamellipodium assembly GO:0030032 20 11 0,000 7,645E-03 0,0170464 ! regulation of embryonic development GO:0045995 27 11 0,000 7,645E-03 0,01703062 ! nucleus localization GO:0051647 19 11 0,000 7,645E-03 0,01701486 ! regulation of synapse organization GO:0050807 17 11 0,000 7,645E-03 0,01699914 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 8,337E-03 0,01852124 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 8,337E-03 0,01850416 ! positive regulation of blood pressure GO:0045777 17 12 0,000 8,337E-03 0,0184871 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 8,337E-03 0,01847008 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 8,337E-03 0,01845309 ! virus-host interaction GO:0019048 29 12 0,000 8,337E-03 0,01843613 ! regulation of B cell proliferation GO:0030888 20 12 0,000 8,337E-03 0,0184192 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 8,337E-03 0,0184023 ! cartilage condensation GO:0001502 20 12 0,000 8,337E-03 0,01838543 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 8,337E-03 0,0183686 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 8,337E-03 0,01835179 ! protein complex disassembly GO:0043241 27 12 0,000 8,337E-03 0,01833502 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 8,337E-03 0,01831827 ! regulation of cell projection assembly GO:0060491 30 12 0,000 8,337E-03 0,01830156 ! hippocampus development GO:0021766 26 12 0,000 8,337E-03 0,01828487 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 8,337E-03 0,01826822 ! cytokine biosynthetic process GO:0042089 21 12 0,000 8,337E-03 0,0182516 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 8,337E-03 0,01823501 ! positive regulation of cell growth GO:0030307 22 12 0,000 8,337E-03 0,01821844 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 8,337E-03 0,01820191 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 8,337E-03 0,01818541 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 8,337E-03 0,01816894 ! drug transport GO:0015893 16 12 0,000 8,337E-03 0,0181525 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 8,337E-03 0,01813608 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 8,337E-03 0,0181197 ! tyrosine metabolic process GO:0006570 16 12 0,000 8,337E-03 0,01810335 ! polyamine metabolic process GO:0006595 17 12 0,000 8,337E-03 0,01808702 ! focal adhesion formation GO:0048041 35 12 0,000 8,337E-03 0,01807073 ! mitotic spindle organization GO:0007052 21 12 0,000 8,337E-03 0,01805446 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 8,337E-03 0,01803823 ! forebrain cell migration GO:0021885 21 12 0,000 8,337E-03 0,01802202 ! asymmetric protein localization GO:0008105 20 12 0,000 8,337E-03 0,01800584 ! membrane protein proteolysis GO:0033619 25 12 0,000 8,337E-03 0,01798969 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 8,337E-03 0,01797357 ! entry into host cell GO:0030260 32 12 0,000 8,337E-03 0,01795748 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 8,337E-03 0,01794142 ! monoamine transport GO:0015844 18 12 0,000 8,337E-03 0,01792539 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 8,337E-03 0,01790938 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 8,337E-03 0,01789341 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 8,337E-03 0,01787746 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 8,337E-03 0,01786154 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 8,337E-03 0,01784565 ! protein targeting to peroxisome GO:0006625 23 12 0,000 8,337E-03 0,01782978 ! protein homotetramerization GO:0051289 21 12 0,000 8,337E-03 0,01781395 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 8,337E-03 0,01779814 ! regulation of phagocytosis GO:0050764 16 12 0,000 8,337E-03 0,01778236 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 8,337E-03 0,01776661 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 8,337E-03 0,01775089 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 8,337E-03 0,0177352 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 8,337E-03 0,01771953 ! cranial nerve development GO:0021545 20 12 0,000 8,337E-03 0,01770389 ! fucose catabolic process GO:0019317 22 12 0,000 8,337E-03 0,01768828 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 8,337E-03 0,01767269 ! histone acetylation GO:0016573 26 12 0,000 8,337E-03 0,01765714 ! histone methylation GO:0016571 26 12 0,000 8,337E-03 0,01764161 ! mRNA polyadenylation GO:0006378 23 12 0,000 8,337E-03 0,01762611 ! autonomic nervous system development GO:0048483 24 12 0,000 8,337E-03 0,01761063 ! gland morphogenesis GO:0022612 29 12 0,000 8,337E-03 0,01759518 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 8,337E-03 0,01757976 ! peptidyl-lysine modification GO:0018205 21 12 0,000 8,337E-03 0,01756437 ! T cell homeostasis GO:0043029 25 12 0,000 8,337E-03 0,017549 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 8,337E-03 0,01753366 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 8,337E-03 0,01751835 ! spleen development GO:0048536 22 12 0,000 8,337E-03 0,01750306 ! digestive tract morphogenesis GO:0048546 26 12 0,000 8,337E-03 0,0174878 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 8,337E-03 0,01747257 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 8,337E-03 0,01745736 ! regulation of RNA splicing GO:0043484 20 12 0,000 8,337E-03 0,01744218 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 8,337E-03 0,01742703 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 8,337E-03 0,0174119 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 8,337E-03 0,0173968 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 8,337E-03 0,01738172 ! response to cold GO:0009409 17 12 0,000 8,337E-03 0,01736667 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 8,337E-03 0,01735165 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 8,337E-03 0,01733665 ! cGMP metabolic process GO:0046068 18 13 0,000 9,029E-03 0,01875893 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 9,029E-03 0,01874274 ! regulation of chemokine production GO:0032642 18 13 0,000 9,029E-03 0,01872659 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 9,029E-03 0,01871046 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 9,029E-03 0,01869436 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 9,029E-03 0,01867828 ! lipid localization GO:0010876 28 13 0,000 9,029E-03 0,01866223 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 9,029E-03 0,01864622 ! organelle fusion GO:0048284 32 13 0,000 9,029E-03 0,01863022 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 9,029E-03 0,01861426 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 9,029E-03 0,01859832 ! pseudouridine synthesis GO:0001522 17 13 0,000 9,029E-03 0,01858241 ! endocrine pancreas development GO:0031018 22 13 0,000 9,029E-03 0,01856653 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 9,029E-03 0,01855068 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 9,029E-03 0,01853485 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 9,029E-03 0,01851905 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 9,029E-03 0,01850327 ! methionine metabolic process GO:0006555 27 13 0,000 9,029E-03 0,01848752 ! plasma membrane organization GO:0007009 24 13 0,000 9,029E-03 0,0184718 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 9,029E-03 0,01845611 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 9,029E-03 0,01844044 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 9,029E-03 0,0184248 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 9,029E-03 0,01840919 ! cell-cell junction assembly GO:0007043 27 13 0,000 9,029E-03 0,0183936 ! response to X-ray GO:0010165 25 13 0,000 9,029E-03 0,01837804 ! cytokine metabolic process GO:0042107 22 13 0,000 9,029E-03 0,0183625 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 9,029E-03 0,01834699 ! exocrine system development GO:0035272 32 13 0,000 9,029E-03 0,01833151 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 9,029E-03 0,01831606 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 9,029E-03 0,01830062 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 9,029E-03 0,01828522 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 9,029E-03 0,01826984 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 9,029E-03 0,01825449 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 9,029E-03 0,01823916 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 9,029E-03 0,01822386 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 9,029E-03 0,01820858 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 9,029E-03 0,01819333 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 9,029E-03 0,01817811 ! regulation of cellular pH GO:0030641 22 13 0,000 9,029E-03 0,01816291 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 9,029E-03 0,01814774 ! ribosome assembly GO:0042255 17 13 0,000 9,029E-03 0,01813259 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 9,029E-03 0,01811747 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 9,029E-03 0,01810237 ! chromatin silencing GO:0006342 26 13 0,000 9,029E-03 0,0180873 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 9,029E-03 0,01807225 ! regulation of epidermis development GO:0045682 19 13 0,000 9,029E-03 0,01805722 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 9,029E-03 0,01804223 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 9,029E-03 0,01802725 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 9,029E-03 0,01801231 ! regulation of mRNA stability GO:0043488 31 13 0,000 9,029E-03 0,01799738 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 9,029E-03 0,01798248 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 9,029E-03 0,01796761 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 9,029E-03 0,01795276 ! mRNA 3'-end processing GO:0031124 24 13 0,000 9,029E-03 0,01793794 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 9,029E-03 0,01792314 ! embryonic placenta development GO:0001892 23 13 0,000 9,029E-03 0,01790836 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 9,029E-03 0,01789361 ! insulin secretion GO:0030073 23 13 0,000 9,029E-03 0,01787888 ! actin filament polymerization GO:0030041 24 13 0,000 9,029E-03 0,01786418 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 9,029E-03 0,0178495 ! acrosome reaction GO:0007340 18 13 0,000 9,029E-03 0,01783485 ! rRNA transcription GO:0009303 25 14 0,000 9,72E-03 0,01918463 ! lactation GO:0007595 26 14 0,000 9,72E-03 0,01916891 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 9,72E-03 0,01915321 ! reproductive cellular process GO:0048610 20 14 0,000 9,72E-03 0,01913754 ! tRNA modification GO:0006400 20 14 0,000 9,72E-03 0,01912189 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 9,72E-03 0,01910627 ! regulation of S phase GO:0033261 23 14 0,000 9,72E-03 0,01909067 ! water transport GO:0006833 21 14 0,000 9,72E-03 0,0190751 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 9,72E-03 0,01905955 ! non-recombinational repair GO:0000726 25 14 0,000 9,72E-03 0,01904403 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 9,72E-03 0,01902854 ! retina development in camera-type eye GO:0060041 27 14 0,000 9,72E-03 0,01901306 ! hair follicle morphogenesis GO:0031069 26 14 0,000 9,72E-03 0,01899762 ! RNA polyadenylation GO:0043631 30 14 0,000 9,72E-03 0,0189822 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 9,72E-03 0,0189668 ! palate development GO:0060021 31 14 0,000 9,72E-03 0,01895143 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 9,72E-03 0,01893609 ! regulated secretory pathway GO:0045055 23 14 0,000 9,72E-03 0,01892077 ! regulation of mRNA processing GO:0050684 24 14 0,000 9,72E-03 0,01890547 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 9,72E-03 0,0188902 ! arginine metabolic process GO:0006525 17 14 0,000 9,72E-03 0,01887496 ! regulation of heart rate GO:0002027 24 14 0,000 9,72E-03 0,01885973 ! organic alcohol transport GO:0015850 29 14 0,000 9,72E-03 0,01884454 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 9,72E-03 0,01882936 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 9,72E-03 0,01881422 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 9,72E-03 0,01879909 ! neutral amino acid transport GO:0015804 26 14 0,000 9,72E-03 0,01878399 ! L-amino acid transport GO:0015807 30 14 0,000 9,72E-03 0,01876892 ! bone mineralization GO:0030282 17 14 0,000 9,72E-03 0,01875386 ! stem cell development GO:0048864 43 14 0,000 9,72E-03 0,01873884 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 9,72E-03 0,01872383 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 9,72E-03 0,01870886 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 9,72E-03 0,0186939 ! cerebellum development GO:0021549 21 14 0,000 9,72E-03 0,01867897 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 9,72E-03 0,01866406 ! negative regulation of protein secretion GO:0050709 28 14 0,000 9,72E-03 0,01864918 ! response to gamma radiation GO:0010332 28 14 0,000 9,72E-03 0,01863432 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 9,72E-03 0,01861948 ! cofactor transport GO:0051181 26 14 0,000 9,72E-03 0,01860467 ! NADP metabolic process GO:0006739 24 14 0,000 9,72E-03 0,01858988 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 9,72E-03 0,01857511 ! protein-chromophore linkage GO:0018298 19 14 0,000 9,72E-03 0,01856037 ! intestinal absorption GO:0050892 25 14 0,000 9,72E-03 0,01854565 ! cAMP biosynthetic process GO:0006171 23 14 0,000 9,72E-03 0,01853096 ! oxygen transport GO:0015671 21 14 0,000 9,72E-03 0,01851629 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 9,72E-03 0,01850164 ! male genitalia development GO:0030539 24 14 0,000 9,72E-03 0,01848701 ! regulation of RNA stability GO:0043487 32 14 0,000 9,72E-03 0,01847241 ! regulation of axon extension GO:0030516 37 14 0,000 9,72E-03 0,01845783 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 9,72E-03 0,01844327 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 9,72E-03 0,01842874 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,01041072 0,01972299 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,01041072 0,01970747 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,01041072 0,01969198 ! superoxide anion generation GO:0042554 20 15 0,000 0,01041072 0,01967651 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,01041072 0,01966106 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,01041072 0,01964564 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,01041072 0,01963025 ! copper ion transport GO:0006825 20 15 0,000 0,01041072 0,01961487 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,01041072 0,01959952 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,01041072 0,0195842 ! sulfate transport GO:0008272 23 15 0,000 0,01041072 0,0195689 ! response to cAMP GO:0051591 22 15 0,000 0,01041072 0,01955362 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,01041072 0,01953837 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,01041072 0,01952314 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,01041072 0,01950794 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,01041072 0,01949276 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,01041072 0,0194776 ! response to hexose stimulus GO:0009746 22 15 0,000 0,01041072 0,01946247 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,01041072 0,01944735 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,01041072 0,01943227 ! pituitary gland development GO:0021983 29 15 0,000 0,01041072 0,0194172 ! vesicle coating GO:0006901 33 15 0,000 0,01041072 0,01940216 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,01041072 0,01938715 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,01041072 0,01937215 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,01041072 0,01935718 ! regulation of exocytosis GO:0017157 22 15 0,000 0,01041072 0,01934223 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,01041072 0,01932731 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,01041072 0,01931241 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,01041072 0,01929753 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,01041072 0,01928267 ! regulation of vasodilation GO:0042312 26 15 0,000 0,01041072 0,01926784 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,01041072 0,01925303 ! histone deacetylation GO:0016575 20 15 0,000 0,01041072 0,01923824 ! mRNA splice site selection GO:0006376 38 15 0,000 0,01041072 0,01922348 ! tissue regeneration GO:0042246 26 15 0,000 0,01041072 0,01920874 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,01041072 0,01919402 ! water homeostasis GO:0030104 27 15 0,000 0,01041072 0,01917932 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,01041072 0,01916465 ! muscle maintenance GO:0046716 26 15 0,000 0,01041072 0,01914999 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,01041072 0,01913536 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,01041072 0,01912076 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,01041072 0,01910617 ! dopamine metabolic process GO:0042417 35 15 0,000 0,01041072 0,01909161 ! heme biosynthetic process GO:0006783 29 15 0,000 0,01041072 0,01907707 ! cell killing GO:0001906 29 15 0,000 0,01041072 0,01906255 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,01041072 0,01904806 ! detection of bacterium GO:0016045 18 15 0,000 0,01041072 0,01903358 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,01041072 0,01901913 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,01041072 0,0190047 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,01041072 0,01899029 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,01041072 0,0189759 ! peptide hormone processing GO:0016486 23 15 0,000 0,01041072 0,01896154 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,01110109 0,02020364 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,01110109 0,02018837 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,01110109 0,02017312 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,01110109 0,0201579 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,01110109 0,02014269 ! bone remodeling GO:0046849 27 16 0,000 0,01110109 0,02012751 ! filopodium assembly GO:0046847 32 16 0,000 0,01110109 0,02011236 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,01110109 0,02009722 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,01110109 0,02008211 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,01110109 0,02006703 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,01110109 0,02005196 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,01110109 0,02003692 ! startle response GO:0001964 28 16 0,000 0,01110109 0,0200219 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,01110109 0,0200069 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,01110109 0,01999192 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,01110109 0,01997697 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,01110109 0,01996204 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,01110109 0,01994713 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,01110109 0,01993225 ! glutamate metabolic process GO:0006536 22 16 0,000 0,01110109 0,01991738 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,01110109 0,01990254 ! response to osmotic stress GO:0006970 25 16 0,000 0,01110109 0,01988772 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,01110109 0,01987293 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,01110109 0,01985815 ! fructose metabolic process GO:0006000 25 16 0,000 0,01110109 0,0198434 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,01110109 0,01982866 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 32 16 0,000 0,01110109 0,01981396 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,01110109 0,01979927 ! negative regulation of immune response GO:0050777 35 16 0,000 0,01110109 0,0197846 ! axon cargo transport GO:0008088 43 16 0,000 0,01110109 0,01976996 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,01110109 0,01975533 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,01110109 0,01974073 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,01110109 0,01972615 ! DNA replication initiation GO:0006270 27 16 0,000 0,01110109 0,0197116 ! neuron recognition GO:0008038 35 16 0,000 0,01110109 0,01969706 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,01110109 0,01968254 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,01110109 0,01966805 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,01110109 0,01965358 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,01110109 0,01963913 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,01110109 0,0196247 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,01110109 0,01961029 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,01110109 0,0195959 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,01110109 0,01958153 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,01110109 0,01956719 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,01110109 0,01955286 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,01110109 0,01953856 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,01110109 0,01952428 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,01110109 0,01951002 ! defense response to virus GO:0051607 37 16 0,000 0,01110109 0,01949577 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,01179099 0,02069229 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,01179099 0,02067721 ! metencephalon development GO:0022037 30 17 0,000 0,01179099 0,02066215 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,01179099 0,02064711 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,01179099 0,02063209 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,01179099 0,0206171 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,01179099 0,02060213 ! signal complex assembly GO:0007172 41 17 0,000 0,01179099 0,02058717 ! endothelial cell migration GO:0043542 28 17 0,000 0,01179099 0,02057225 ! inositol metabolic process GO:0006020 28 17 0,000 0,01179099 0,02055734 ! gene silencing by RNA GO:0031047 36 17 0,000 0,01179099 0,02054245 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,01179099 0,02052759 ! glial cell development GO:0021782 27 17 0,000 0,01179099 0,02051275 ! limbic system development GO:0021761 36 17 0,000 0,01179099 0,02049792 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,01179099 0,02048312 ! adult walking behavior GO:0007628 33 17 0,000 0,01179099 0,02046835 ! heart looping GO:0001947 30 17 0,000 0,01179099 0,02045359 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,01179099 0,02043885 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,01179099 0,02042414 ! myoblast differentiation GO:0045445 45 17 0,000 0,01179099 0,02040944 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,01179099 0,02039477 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,01179099 0,02038012 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,01179099 0,02036549 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,01179099 0,02035088 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,01179099 0,02033629 ! glycine metabolic process GO:0006544 28 17 0,000 0,01179099 0,02032172 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,01179099 0,02030718 ! NAD metabolic process GO:0019674 29 17 0,000 0,01179099 0,02029265 ! membrane budding GO:0006900 37 17 0,000 0,01179099 0,02027815 ! DNA integration GO:0015074 29 17 0,000 0,01179099 0,02026366 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,01179099 0,0202492 ! regulation of protein binding GO:0043393 33 17 0,000 0,01179099 0,02023476 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,01179099 0,02022033 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,01179099 0,02020593 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,01179099 0,02019155 ! genitalia development GO:0048806 30 17 0,000 0,01179099 0,02017719 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,01179099 0,02016285 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,01179099 0,02014853 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,01179099 0,02013423 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,01179099 0,02011995 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,01179099 0,02010569 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,01179099 0,02009145 ! steroid catabolic process GO:0006706 31 17 0,000 0,01179099 0,02007723 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,01179099 0,02006303 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,01179099 0,02004885 ! gas transport GO:0015669 25 17 0,000 0,01179099 0,02003469 ! organic cation transport GO:0015695 31 17 0,000 0,01179099 0,02002056 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,01179099 0,02000644 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,01179099 0,01999234 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,01179099 0,01997826 ! microspike assembly GO:0030035 36 17 0,000 0,01179099 0,0199642 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,01179099 0,01995016 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,01179099 0,01993614 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,01248044 0,02108704 ! neuron maturation GO:0042551 42 18 0,000 0,01248044 0,02107224 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,01248044 0,02105746 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,01248044 0,0210427 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,01248044 0,02102797 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,01248044 0,02101325 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,01248044 0,02099856 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,01248044 0,02098388 ! memory GO:0007613 31 18 0,000 0,01248044 0,02096923 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,01248044 0,0209546 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,01248044 0,02093999 ! patterning of blood vessels GO:0001569 39 18 0,000 0,01248044 0,02092539 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,01248044 0,02091082 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,01248044 0,02089627 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,01248044 0,02088174 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,01248044 0,02086723 ! glutamine metabolic process GO:0006541 29 18 0,000 0,01248044 0,02085274 ! response to retinoic acid GO:0032526 26 18 0,000 0,01248044 0,02083826 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,01248044 0,02082381 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,01248044 0,02080938 ! response to fungus GO:0009620 21 18 0,000 0,01248044 0,02079497 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,01248044 0,02078058 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,01248044 0,02076621 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,01248044 0,02075186 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,01248044 0,02073753 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,01248044 0,02072322 ! vitamin transport GO:0051180 27 18 0,000 0,01248044 0,02070892 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,01248044 0,02069465 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,01248044 0,0206804 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,01248044 0,02066617 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,01248044 0,02065195 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,01248044 0,02063776 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,01248044 0,02062358 ! nerve development GO:0021675 28 18 0,000 0,01248044 0,02060943 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,01248044 0,02059529 ! protein secretion GO:0009306 39 19 0,000 0,01316943 0,02171737 ! positive regulation of translation GO:0045727 30 19 0,000 0,01316943 0,0217025 ! negative regulation of defense response GO:0031348 25 19 0,000 0,01316943 0,02168764 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,01316943 0,02167281 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,01316943 0,021658 ! skin development GO:0043588 36 19 0,000 0,01316943 0,0216432 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,01316943 0,02162843 ! lipid phosphorylation GO:0046834 35 19 0,000 0,01316943 0,02161368 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,01316943 0,02159894 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,01316943 0,02158423 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,01316943 0,02156954 ! bile acid metabolic process GO:0008206 29 19 0,000 0,01316943 0,02155486 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,01316943 0,02154021 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,01316943 0,02152558 ! cerebral cortex development GO:0021987 36 19 0,000 0,01316943 0,02151096 ! pigmentation during development GO:0048066 41 19 0,000 0,01316943 0,02149637 ! response to vitamin A GO:0033189 27 19 0,000 0,01316943 0,0214818 ! heme metabolic process GO:0042168 36 19 0,000 0,01316943 0,02146724 ! actin filament bundle formation GO:0051017 42 19 0,000 0,01316943 0,02145271 ! neuromuscular junction development GO:0007528 34 19 0,000 0,01316943 0,02143819 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,01316943 0,0214237 ! plasma membrane fusion GO:0045026 28 19 0,000 0,01316943 0,02140922 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,01316943 0,02139477 ! peptide cross-linking GO:0018149 37 19 0,000 0,01316943 0,02138033 ! protein export from nucleus GO:0006611 36 19 0,000 0,01316943 0,02136591 ! heart process GO:0003015 30 19 0,000 0,01316943 0,02135152 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,01316943 0,02133714 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,01316943 0,02132278 ! visual learning GO:0008542 36 19 0,000 0,01316943 0,02130844 ! cellular pigmentation GO:0033059 36 19 0,000 0,01316943 0,02129412 ! G1 phase GO:0051318 40 19 0,000 0,01316943 0,02127982 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,01316943 0,02126554 ! cell-cell junction organization GO:0045216 35 19 0,000 0,01316943 0,02125127 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,01316943 0,02123703 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,01316943 0,02122281 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,01316943 0,0212086 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,01316943 0,02119441 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,01316943 0,02118025 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,01316943 0,0211661 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,01316943 0,02115197 ! cilium assembly GO:0042384 37 19 0,000 0,01316943 0,02113786 ! peptide hormone secretion GO:0030072 31 19 0,000 0,01316943 0,02112377 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,01385796 0,02221336 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,01385796 0,02219857 ! positive regulation of ossification GO:0045778 47 20 0,000 0,01385796 0,0221838 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,01385796 0,02216905 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,01385796 0,02215432 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,01385796 0,02213961 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,01385796 0,02212492 ! cAMP metabolic process GO:0046058 36 20 0,000 0,01385796 0,02211025 ! response to vitamin GO:0033273 31 20 0,000 0,01385796 0,0220956 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,01385796 0,02208097 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,01385796 0,02206635 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,01385796 0,02205176 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,01385796 0,02203718 ! response to alkaloid GO:0043279 38 20 0,000 0,01385796 0,02202263 ! retinoid metabolic process GO:0001523 32 20 0,000 0,01385796 0,02200809 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,01385796 0,02199357 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,01385796 0,02197908 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,01385796 0,0219646 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,01385796 0,02195014 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,01385796 0,0219357 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,01385796 0,02192127 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,01385796 0,02190687 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,01385796 0,02189249 ! body fluid secretion GO:0007589 31 20 0,000 0,01385796 0,02187812 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,01385796 0,02186378 ! peptide secretion GO:0002790 35 20 0,000 0,01385796 0,02184945 ! stem cell differentiation GO:0048863 53 20 0,000 0,01385796 0,02183514 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,01385796 0,02182085 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,01385796 0,02180658 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,01385796 0,02179233 ! sensory perception of pain GO:0019233 30 20 0,000 0,01385796 0,02177809 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,01385796 0,02176388 ! diencephalon development GO:0021536 34 20 0,000 0,01385796 0,02174968 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,01385796 0,0217355 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,01385796 0,02172134 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,01385796 0,0217072 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,01385796 0,02169308 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,01385796 0,02167897 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,01385796 0,02166488 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,01385796 0,02165082 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,01385796 0,02163677 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,01385796 0,02162273 ! regulation of glucose import GO:0046324 29 20 0,000 0,01385796 0,02160872 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,01385796 0,02159473 ! actin filament-based movement GO:0030048 43 20 0,000 0,01385796 0,02158075 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,01385796 0,02156679 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,01385796 0,02155285 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,01385796 0,02153893 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,01385796 0,02152502 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,01385796 0,02151113 ! regulation of cell killing GO:0031341 42 21 0,000 0,01454604 0,02256465 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,01454604 0,02255011 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,01454604 0,02253559 ! hormone secretion GO:0046879 38 21 0,000 0,01454604 0,02252108 ! glycerol metabolic process GO:0006071 34 21 0,000 0,01454604 0,0225066 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,01454604 0,02249214 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,01454604 0,02247769 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,01454604 0,02246326 ! axis specification GO:0009798 38 21 0,000 0,01454604 0,02244885 ! ovarian follicle development GO:0001541 35 21 0,000 0,01454604 0,02243446 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,01454604 0,02242009 ! smooth muscle contraction GO:0006939 46 21 0,000 0,01454604 0,02240574 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,01454604 0,0223914 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,01454604 0,02237709 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,01454604 0,02236279 ! cell aging GO:0007569 44 21 0,000 0,01454604 0,02234851 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,01454604 0,02233425 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,01454604 0,02232 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,01454604 0,02230578 ! cytolysis GO:0019835 24 21 0,000 0,01454604 0,02229157 ! vasodilation GO:0042311 39 21 0,000 0,01454604 0,02227738 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,01454604 0,02226321 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,01454604 0,02224906 ! oogenesis GO:0048477 36 21 0,000 0,01454604 0,02223492 ! DNA modification GO:0006304 34 21 0,000 0,01454604 0,0222208 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,01454604 0,0222067 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,01454604 0,02219262 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,01454604 0,02217856 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,01454604 0,02216451 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,01454604 0,02215048 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,01454604 0,02213647 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,01454604 0,02212248 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,01454604 0,02210851 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,01454604 0,02209455 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,01454604 0,02208061 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,01454604 0,02206669 ! collagen catabolic process GO:0030574 28 21 0,000 0,01454604 0,02205278 ! sperm-egg recognition GO:0035036 21 21 0,000 0,01454604 0,02203889 ! gut development GO:0048565 39 21 0,000 0,01454604 0,02202503 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,01523365 0,02305168 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,01523365 0,02303719 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,01523365 0,02302272 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,01523365 0,02300827 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,01523365 0,02299383 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,01523365 0,02297942 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,01523365 0,02296502 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,01523365 0,02295064 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,01523365 0,02293628 ! regeneration GO:0031099 41 22 0,000 0,01523365 0,02292193 ! keratinization GO:0031424 28 22 0,000 0,01523365 0,02290761 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,01523365 0,0228933 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,01523365 0,02287901 ! sensory perception of taste GO:0050909 28 22 0,000 0,01523365 0,02286474 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,01523365 0,02285048 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,01523365 0,02283624 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,01523365 0,02282203 ! vacuolar transport GO:0007034 36 22 0,000 0,01523365 0,02280782 ! lysosome organization GO:0007040 41 22 0,000 0,01523365 0,02279364 ! central nervous system neuron development GO:0021954 46 22 0,000 0,01523365 0,02277947 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,01523365 0,02276532 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,01523365 0,02275119 ! fucose metabolic process GO:0006004 39 22 0,000 0,01523365 0,02273708 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,01523365 0,02272298 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,01523365 0,0227089 ! ureteric bud development GO:0001657 43 22 0,000 0,01523365 0,02269484 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,01523365 0,0226808 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,01523365 0,02266677 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,01523365 0,02265276 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,01523365 0,02263877 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,01523365 0,0226248 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,01523365 0,02261084 ! sarcomere organization GO:0045214 30 22 0,000 0,01523365 0,0225969 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,01523365 0,02258298 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,01523365 0,02256907 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,01523365 0,02255518 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,01523365 0,02254131 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,01523365 0,02252746 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,01523365 0,02251362 ! protein stabilization GO:0050821 39 22 0,000 0,01523365 0,0224998 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,01592081 0,02350029 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,01592081 0,02348589 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,01592081 0,0234715 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,01592081 0,02345712 ! gluconeogenesis GO:0006094 33 23 0,000 0,01592081 0,02344277 ! viral genome replication GO:0019079 41 23 0,000 0,01592081 0,02342843 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,01592081 0,02341411 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,01592081 0,0233998 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,01592081 0,02338552 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,01592081 0,02337125 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,01592081 0,023357 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,01592081 0,02334277 ! visual behavior GO:0007632 42 23 0,000 0,01592081 0,02332855 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,01592081 0,02331435 ! response to ethanol GO:0045471 46 23 0,000 0,01592081 0,02330017 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,01592081 0,02328601 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,01592081 0,02327186 ! peroxisome organization GO:0007031 37 23 0,000 0,01592081 0,02325773 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,01592081 0,02324362 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,01592081 0,02322952 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,01592081 0,02321544 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,01592081 0,02320138 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,01592081 0,02318734 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,01592081 0,02317331 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,01592081 0,0231593 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,01592081 0,02314531 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,01592081 0,02313133 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,01592081 0,02311737 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,01592081 0,02310343 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,01592081 0,0230895 ! fatty acid transport GO:0015908 44 23 0,000 0,01592081 0,02307559 ! platelet activation GO:0030168 37 23 0,000 0,01592081 0,0230617 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,01592081 0,02304782 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,01592081 0,02303396 ! hormone transport GO:0009914 40 23 0,000 0,01592081 0,02302012 ! cell-cell recognition GO:0009988 25 23 0,000 0,01592081 0,02300629 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,01592081 0,02299249 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,01592081 0,02297869 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,01592081 0,02296492 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,01592081 0,02295116 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,01592081 0,02293741 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,01660752 0,02391244 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,01660752 0,02389814 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,01660752 0,02388386 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,01660752 0,02386959 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,01660752 0,02385534 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,01660752 0,0238411 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,01660752 0,02382689 ! vesicle docking GO:0048278 47 24 0,000 0,01660752 0,02381269 ! spinal cord development GO:0021510 47 24 0,000 0,01660752 0,0237985 ! vacuole organization GO:0007033 43 24 0,000 0,01660752 0,02378434 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,01660752 0,02377019 ! digestive system process GO:0022600 39 24 0,000 0,01660752 0,02375606 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,01660752 0,02374194 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,01660752 0,02372784 ! regulation of behavior GO:0050795 43 24 0,000 0,01660752 0,02371376 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,01660752 0,0236997 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,01660752 0,02368565 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,01660752 0,02367162 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,01660752 0,0236576 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,01660752 0,0236436 ! membrane depolarization GO:0051899 39 24 0,000 0,01660752 0,02362962 ! pallium development GO:0021543 49 24 0,000 0,01660752 0,02361566 ! pentose metabolic process GO:0019321 35 24 0,000 0,01660752 0,02360171 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,01660752 0,02358777 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,01660752 0,02357386 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,01660752 0,02355996 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,01660752 0,02354608 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,01660752 0,02353221 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,01660752 0,02351836 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,01660752 0,02350452 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,01660752 0,02349071 ! regulation of amine transport GO:0051952 40 24 0,000 0,01660752 0,0234769 ! protein tetramerization GO:0051262 52 24 0,000 0,01660752 0,02346312 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,01729377 0,02441831 ! myelination GO:0042552 45 25 0,000 0,01729377 0,02440399 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,01729377 0,02438968 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,01729377 0,0243754 ! phototransduction GO:0007602 33 25 0,000 0,01729377 0,02436112 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,01729377 0,02434687 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,01729377 0,02433263 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,01729377 0,02431841 ! sperm motility GO:0030317 31 25 0,000 0,01729377 0,02430421 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,01729377 0,02429002 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,01729377 0,02427585 ! receptor metabolic process GO:0043112 46 25 0,000 0,01729377 0,02426169 ! chromosome condensation GO:0030261 45 25 0,000 0,01729377 0,02424755 ! response to starvation GO:0042594 42 25 0,000 0,01729377 0,02423343 ! osteoblast differentiation GO:0001649 60 25 0,000 0,01729377 0,02421933 ! neural crest cell development GO:0014032 54 25 0,000 0,01729377 0,02420524 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,01729377 0,02419116 ! negative regulation of cell development GO:0010721 73 25 0,000 0,01729377 0,02417711 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,01729377 0,02416307 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,01729377 0,02414904 ! interaction with host GO:0051701 62 25 0,000 0,01729377 0,02413504 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,01729377 0,02412104 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,01729377 0,02410707 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,01729377 0,02409311 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,01729377 0,02407917 ! immunoglobulin production GO:0002377 55 25 0,000 0,01729377 0,02406524 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,01729377 0,02405133 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,01729377 0,02403744 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,01729377 0,02402356 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,01729377 0,02400969 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,01729377 0,02399585 ! telomere organization GO:0032200 43 25 0,000 0,01729377 0,02398202 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,01729377 0,0239682 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,01729377 0,0239544 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,01797956 0,02489 ! embryonic pattern specification GO:0009880 44 26 0,000 0,01797956 0,02487568 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,01797956 0,02486139 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,01797956 0,02484711 ! initiation of viral infection GO:0019059 57 26 0,000 0,01797956 0,02483284 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,01797956 0,0248186 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,01797956 0,02480437 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,01797956 0,02479015 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,01797956 0,02477595 ! molting cycle process GO:0022404 50 26 0,000 0,01797956 0,02476177 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,01797956 0,02474761 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,01797956 0,02473346 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,01797956 0,02471932 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,01797956 0,02470521 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,01797956 0,0246911 GO:0051297|centrosome organization, ! insulin receptor signaling pathway GO:0008286 64 26 0,000 0,01797956 0,02467702 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,01797956 0,02466295 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,01797956 0,0246489 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,01797956 0,02463486 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,01797956 0,02462084 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,01797956 0,02460683 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,01797956 0,02459285 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,01797956 0,02457887 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,01797956 0,02456491 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,01797956 0,02455097 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,01797956 0,02453705 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,01797956 0,02452314 ! blastocyst development GO:0001824 49 26 0,000 0,01797956 0,02450924 ! leukocyte proliferation GO:0070661 52 26 0,000 0,01797956 0,02449537 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,01797956 0,0244815 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,01797956 0,02446766 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,01866489 0,02538594 ! neuron fate commitment GO:0048663 48 27 0,000 0,01866489 0,0253716 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,01866489 0,02535727 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,01866489 0,02534296 ! iron ion transport GO:0006826 59 27 0,000 0,01866489 0,02532867 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,01866489 0,02531439 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,01866489 0,02530013 ! protein amino acid acylation GO:0043543 55 27 0,000 0,01866489 0,02528588 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,01866489 0,02527166 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,01866489 0,02525744 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,01866489 0,02524324 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,01866489 0,02522906 ! autophagy GO:0006914 41 27 0,000 0,01866489 0,0252149 ! male gonad development GO:0008584 44 27 0,000 0,01866489 0,02520075 ! response to toxin GO:0009636 47 27 0,000 0,01866489 0,02518661 ! primary neural tube formation GO:0014020 51 27 0,000 0,01866489 0,0251725 ! base-excision repair GO:0006284 41 27 0,000 0,01866489 0,02515839 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,01866489 0,02514431 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,01866489 0,02513024 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,01866489 0,02511618 ! glutathione metabolic process GO:0006749 39 27 0,000 0,01866489 0,02510214 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,01866489 0,02508812 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,01866489 0,02507411 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,01866489 0,02506012 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,01866489 0,02504614 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,01934977 0,0259507 ! circadian rhythm GO:0007623 50 28 0,000 0,01934977 0,02593624 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,01934977 0,0259218 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,01934977 0,02590737 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,01934977 0,02589297 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,01934977 0,02587857 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,01934977 0,0258642 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,01934977 0,02584984 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,01934977 0,02583549 ! synaptogenesis GO:0007416 42 28 0,000 0,01934977 0,02582116 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,01934977 0,02580685 ! lipid oxidation GO:0034440 43 28 0,000 0,01934977 0,02579255 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,01934977 0,02577827 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,01934977 0,025764 ! translational initiation GO:0006413 65 29 0,000 0,0200342 0,02666055 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,0200342 0,02664581 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,0200342 0,02663109 ! regulation of pH GO:0006885 43 29 0,000 0,0200342 0,02661639 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,0200342 0,0266017 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,0200342 0,02658703 ! catechol metabolic process GO:0009712 54 29 0,000 0,0200342 0,02657237 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,0200342 0,02655773 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,0200342 0,0265431 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,0200342 0,0265285 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,0200342 0,0265139 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,0200342 0,02649933 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,0200342 0,02648477 ! cell fate determination GO:0001709 60 29 0,000 0,0200342 0,02647022 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,0200342 0,0264557 ! detection of light stimulus GO:0009583 38 29 0,000 0,0200342 0,02644118 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 0,0200342 0,02642669 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,0200342 0,02641221 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,0200342 0,02639774 ! tissue homeostasis GO:0001894 48 29 0,000 0,0200342 0,02638329 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,0200342 0,02636886 ! phenol metabolic process GO:0018958 55 30 0,000 0,02071817 0,02725419 ! zinc ion transport GO:0006829 45 30 0,000 0,02071817 0,0272393 ! membrane docking GO:0022406 61 30 0,000 0,02071817 0,02722442 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,02071817 0,02720956 ! cell junction assembly GO:0034329 78 30 0,000 0,02071817 0,02719471 ! regulation of innate immune response GO:0045088 51 30 0,000 0,02071817 0,02717989 ! acute-phase response GO:0006953 49 30 0,000 0,02071817 0,02716507 ! myofibril assembly GO:0030239 47 30 0,000 0,02071817 0,02715028 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,02071817 0,0271355 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,02071817 0,02712073 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,02071817 0,02710599 ! phospholipid transport GO:0015914 51 30 0,000 0,02071817 0,02709126 ! ensheathment of neurons GO:0007272 57 30 0,000 0,02071817 0,02707654 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,02071817 0,02706184 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,02071817 0,02704716 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,02071817 0,02703249 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,02071817 0,02701784 ! eye morphogenesis GO:0048592 60 30 0,000 0,02071817 0,0270032 ! regulation of B cell activation GO:0050864 50 30 0,000 0,02071817 0,02698858 ! response to heat GO:0009408 50 30 0,000 0,02071817 0,02697398 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,02140168 0,02784881 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,02140168 0,02783376 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,02140168 0,02781872 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,02140168 0,0278037 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,02140168 0,02778869 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,02140168 0,0277737 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,02140168 0,02775873 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,02140168 0,02774378 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,02140168 0,02772884 ! ovulation cycle process GO:0022602 49 31 0,000 0,02140168 0,02771391 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,02140168 0,027699 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,02140168 0,02768411 ! peptide transport GO:0015833 55 31 0,000 0,02140168 0,02766924 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,02140168 0,02765438 ! iron ion homeostasis GO:0055072 54 31 0,000 0,02140168 0,02763953 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,02140168 0,0276247 ! mesoderm formation GO:0001707 69 31 0,000 0,02140168 0,02760989 ! natural killer cell activation GO:0030101 45 31 0,000 0,02140168 0,02759509 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,02140168 0,02758031 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,02140168 0,02756555 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,02140168 0,0275508 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,02140168 0,02753607 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,02140168 0,02752135 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,02208474 0,02838456 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,02208474 0,0283694 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,02208474 0,02835426 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,02208474 0,02833914 ! cholesterol transport GO:0030301 56 32 0,000 0,02208474 0,02832404 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,02208474 0,02830895 ! spliceosome assembly GO:0000245 67 32 0,000 0,02208474 0,02829387 ! spindle organization GO:0007051 46 32 0,000 0,02208474 0,02827881 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,02208474 0,02826377 ! metanephros development GO:0001656 74 32 0,000 0,02208474 0,02824875 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,02208474 0,02823374 ! response to ionizing radiation GO:0010212 65 32 0,000 0,02208474 0,02821874 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,02208474 0,02820376 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,02208474 0,0281888 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,02208474 0,02817386 ! muscle cell development GO:0055001 49 32 0,000 0,02208474 0,02815892 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,02208474 0,02814401 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,02208474 0,02812911 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,02208474 0,02811423 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,02208474 0,02809936 ! ovulation cycle GO:0042698 51 32 0,000 0,02208474 0,02808451 ! peripheral nervous system development GO:0007422 64 32 0,000 0,02208474 0,02806967 ! BMP signaling pathway GO:0030509 64 32 0,000 0,02208474 0,02805485 ! hindbrain development GO:0030902 61 32 0,000 0,02208474 0,02804005 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,02208474 0,02802526 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,02208474 0,02801049 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,02208474 0,02799573 ! gene silencing GO:0016458 65 32 0,000 0,02208474 0,02798099 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,02276735 0,02883065 ! post-embryonic development GO:0009791 69 33 0,000 0,02276735 0,02881549 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,02276735 0,02880034 ! protein targeting to membrane GO:0006612 68 33 0,000 0,02276735 0,0287852 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,02276735 0,02877009 ! ceramide metabolic process GO:0006672 64 33 0,000 0,02276735 0,02875498 ! formation of primary germ layer GO:0001704 72 33 0,000 0,02276735 0,0287399 ! cell fate specification GO:0001708 52 33 0,000 0,02276735 0,02872483 ! sterol transport GO:0015918 57 33 0,000 0,02276735 0,02870977 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,02276735 0,02869473 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,02276735 0,02867971 ! adult locomotory behavior GO:0008344 59 33 0,000 0,02276735 0,0286647 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,02276735 0,02864971 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,02276735 0,02863473 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,0234495 0,02947727 ! glial cell differentiation GO:0010001 63 34 0,000 0,0234495 0,02946188 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,0234495 0,0294465 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,0234495 0,02943114 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,0234495 0,0294158 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,0234495 0,02940047 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,0234495 0,02938516 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,0234495 0,02936986 ! mismatch repair GO:0006298 46 34 0,000 0,0234495 0,02935458 ! spermatid development GO:0007286 63 34 0,000 0,0234495 0,02933931 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,0234495 0,02932407 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,0234495 0,02930883 ! placenta development GO:0001890 53 34 0,000 0,0234495 0,02929362 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,0234495 0,02927841 ! regulation of muscle development GO:0048634 70 35 0,000 0,0241312 0,03011394 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,0241312 0,03009833 ! negative regulation of secretion GO:0051048 63 35 0,000 0,0241312 0,03008273 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,0241312 0,03006715 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,0241312 0,03005159 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,0241312 0,03003604 ! odontogenesis GO:0042476 66 35 0,000 0,0241312 0,03002051 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,0241312 0,030005 ! female gonad development GO:0008585 58 35 0,000 0,0241312 0,0299895 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,0241312 0,02997402 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,0241312 0,02995855 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,0241312 0,0299431 ! cytokine production GO:0001816 59 35 0,000 0,0241312 0,02992767 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,0241312 0,02991225 ! neural tube formation GO:0001841 67 35 0,000 0,0241312 0,02989684 ! vesicle localization GO:0051648 64 35 0,000 0,0241312 0,02988146 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,02481245 0,03070923 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,02481245 0,03069344 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,02481245 0,03067767 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,02481245 0,03066192 ! cell junction organization GO:0034330 86 36 0,000 0,02481245 0,03064618 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,02481245 0,03063045 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,02481245 0,03061474 ! positive regulation of cell development GO:0010720 80 36 0,000 0,02481245 0,03059905 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,02481245 0,03058338 ! regulation of proteolysis GO:0030162 72 36 0,000 0,02481245 0,03056772 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,02481245 0,03055207 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,02481245 0,03053644 ! aerobic respiration GO:0009060 55 36 0,000 0,02481245 0,03052083 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,02481245 0,03050524 ! embryonic organ development GO:0048568 57 36 0,000 0,02481245 0,03048966 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,02481245 0,03047409 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,02481245 0,03045855 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,02549324 0,0312783 ! meiosis I GO:0007127 65 37 0,000 0,02549324 0,03126235 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,02549324 0,03124643 ! sister chromatid segregation GO:0000819 58 37 0,000 0,02549324 0,03123052 ! actomyosin structure organization GO:0031032 62 37 0,000 0,02549324 0,03121462 ! organic anion transport GO:0015711 68 37 0,000 0,02549324 0,03119875 ! tissue remodeling GO:0048771 76 37 0,000 0,02549324 0,03118289 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,02549324 0,03116704 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,02549324 0,03115121 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,02549324 0,0311354 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,02549324 0,0311196 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,02549324 0,03110382 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,02549324 0,03108806 ! glycogen metabolic process GO:0005977 61 37 0,000 0,02549324 0,03107231 ! pigment metabolic process GO:0042440 80 37 0,000 0,02549324 0,03105658 ! spermatid differentiation GO:0048515 66 37 0,000 0,02549324 0,03104086 ! cellular response to insulin stimulus GO:0032869 82 37 0,000 0,02549324 0,03102516 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,02617358 0,03183703 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,02617358 0,03182094 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,02617358 0,03180487 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,02617358 0,03178881 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,02617358 0,03177277 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,02617358 0,03175675 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,02617358 0,03174074 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,02617358 0,03172475 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,02617358 0,03170878 ! lipid homeostasis GO:0055088 67 38 0,000 0,02617358 0,03169282 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,02617358 0,03167688 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,02617358 0,03166095 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,02617358 0,03164504 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,02617358 0,03162915 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,02617358 0,03161327 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,02617358 0,03159741 ! glucan metabolic process GO:0044042 62 38 0,000 0,02617358 0,03158156 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,02685347 0,03238569 ! mammary gland development GO:0030879 86 39 0,000 0,02685347 0,03236946 ! learning GO:0007612 77 39 0,000 0,02685347 0,03235325 ! ear morphogenesis GO:0042471 60 39 0,000 0,02685347 0,03233706 ! organic ether metabolic process GO:0018904 55 39 0,000 0,02685347 0,03232088 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,02685347 0,03230472 ! segmentation GO:0035282 67 39 0,000 0,02685347 0,03228858 ! ion transmembrane transport GO:0034220 66 39 0,000 0,02685347 0,03227245 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,02685347 0,03225634 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,02685347 0,03224024 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,02685347 0,03222416 ! RNA modification GO:0009451 57 39 0,000 0,02685347 0,0322081 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,02685347 0,03219205 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,02753291 0,03299012 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,02753291 0,0329737 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,02753291 0,0329573 ! feeding behavior GO:0007631 59 40 0,000 0,02753291 0,03294091 ! negative regulation of binding GO:0051100 72 40 0,000 0,02753291 0,03292454 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,02753291 0,03290818 ! mesenchymal cell development GO:0014031 87 40 0,000 0,02753291 0,03289184 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,02753291 0,03287552 ! maintenance of protein location GO:0045185 91 40 0,000 0,02753291 0,03285921 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,02821189 0,03365285 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,02821189 0,03363618 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,02821189 0,03361952 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,02821189 0,03360287 ! gliogenesis GO:0042063 88 41 0,000 0,02821189 0,03358625 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,02821189 0,03356964 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,02821189 0,03355304 ! T cell differentiation GO:0030217 81 41 0,000 0,02821189 0,03353647 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,02821189 0,0335199 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,02821189 0,03350336 ! female gamete generation GO:0007292 61 41 0,000 0,02821189 0,03348683 ! polyol metabolic process GO:0019751 66 41 0,000 0,02821189 0,03347032 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,02821189 0,03345382 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,02889042 0,03424155 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,02889042 0,0342247 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,02889042 0,03420785 ! regulation of tube size GO:0035150 71 42 0,000 0,02889042 0,03419103 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,02889042 0,03417422 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,02889042 0,03415742 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,02889042 0,03414065 ! regulation of intracellular protein transport GO:0033157 80 42 0,000 0,02889042 0,03412389 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,02889042 0,03410714 ! neuron migration GO:0001764 79 42 0,000 0,02889042 0,03409042 ! regulation of protein secretion GO:0050708 71 42 0,000 0,02889042 0,0340737 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,02889042 0,03405701 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,0295685 0,03483929 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,0295685 0,03482223 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,0295685 0,0348052 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,0295685 0,03478818 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,0295685 0,03477117 ! glucose transport GO:0015758 65 43 0,000 0,0295685 0,03475419 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,0295685 0,03473722 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,0295685 0,03472026 ! neural tube development GO:0021915 77 43 0,000 0,0295685 0,03470333 ! regulation of epithelial cell proliferation GO:0050678 111 43 0,000 0,0295685 0,03468641 ! striated muscle contraction GO:0006941 77 43 0,000 0,0295685 0,0346695 ! phagocytosis GO:0006909 90 43 0,000 0,0295685 0,03465262 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,0295685 0,03463575 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,03024613 0,03541226 ! hexose transport GO:0008645 67 44 0,000 0,03024613 0,03539504 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,03024613 0,03537783 ! male sex differentiation GO:0046661 76 44 0,000 0,03024613 0,03536064 ! double-strand break repair GO:0006302 81 44 0,000 0,03024613 0,03534347 ! biopolymer methylation GO:0043414 84 44 0,000 0,03024613 0,03532631 ! B cell differentiation GO:0030183 107 44 0,000 0,03024613 0,03530917 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,03024613 0,03529205 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,03024613 0,03527494 ! developmental growth GO:0048589 82 44 0,000 0,03024613 0,03525785 ! maintenance of location in cell GO:0051651 97 44 0,000 0,03024613 0,03524077 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,03092331 0,03601234 ! glycolysis GO:0006096 65 45 0,000 0,03092331 0,03599492 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,03092331 0,03597751 ! leukocyte migration GO:0050900 68 45 0,000 0,03092331 0,03596012 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,03092331 0,03594275 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,03092331 0,0359254 ! induction of apoptosis by intracellular signals GO:0008629 93 45 0,000 0,03092331 0,03590806 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,03092331 0,03589074 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,03092331 0,03587343 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,03092331 0,03585614 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,03092331 0,03583887 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,03092331 0,03582162 ! cell growth GO:0016049 84 45 0,000 0,03092331 0,03580438 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,03160004 0,03657033 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 0,000 0,03160004 0,03655274 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,03160004 0,03653518 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,03160004 0,03651763 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,03160004 0,0365001 ! pigmentation GO:0043473 100 46 0,000 0,03160004 0,03648258 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,03160004 0,03646509 ! positive regulation of defense response GO:0031349 76 47 0,000 0,03227632 0,03722763 ! endosome transport GO:0016197 108 47 0,000 0,03227632 0,03720979 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,03227632 0,03719197 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,03227632 0,03717417 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,03227632 0,03715638 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,03227632 0,03713861 ! JNK cascade GO:0007254 91 47 0,000 0,03227632 0,03712086 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,03227632 0,03710312 ! methylation GO:0032259 90 47 0,000 0,03227632 0,0370854 ! protein homooligomerization GO:0051260 76 47 0,000 0,03227632 0,0370677 ! Notch signaling pathway GO:0007219 96 48 0,000 0,03295215 0,0378258 ! cellular component disassembly GO:0022411 86 48 0,000 0,03295215 0,03780776 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,03295215 0,03778974 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,03295215 0,03777174 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,03295215 0,03775375 ! activation of caspase activity GO:0006919 84 48 0,000 0,03295215 0,03773578 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,03295215 0,03771783 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,03295215 0,0376999 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,03295215 0,03768198 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,03295215 0,03766408 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,03362753 0,03841778 ! regulation of action potential GO:0001508 95 49 0,000 0,03362753 0,03839955 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,03362753 0,03838133 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,03362753 0,03836313 ! regulation of ion transport GO:0043269 77 49 0,000 0,03362753 0,03834495 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,03362753 0,03832679 ! peptide metabolic process GO:0006518 76 49 0,000 0,03362753 0,03830864 ! response to temperature stimulus GO:0009266 76 49 0,000 0,03362753 0,03829051 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,03362753 0,0382724 ! endocrine system development GO:0035270 104 49 0,000 0,03362753 0,0382543 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,03362753 0,03823622 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,03362753 0,03821816 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,03362753 0,03820012 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,03362753 0,03818209 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,03430246 0,03893006 ! neuromuscular process GO:0050905 99 50 0,000 0,03430246 0,03891171 ! regulation of ossification GO:0030278 117 50 0,000 0,03430246 0,03889337 ! inner ear development GO:0048839 79 50 0,000 0,03430246 0,03887505 ! histone modification GO:0016570 91 50 0,000 0,03430246 0,03885675 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,03430246 0,03883846 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,03430246 0,03882019 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,03430246 0,03880194 ! positive regulation of binding GO:0051099 78 51 0,000 0,03497695 0,0395463 ! viral infectious cycle GO:0019058 99 51 0,000 0,03497695 0,03952773 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,03497695 0,03950917 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,03497695 0,03949063 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,03497695 0,03947211 ! excretion GO:0007588 83 51 0,000 0,03497695 0,0394536 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,03497695 0,03943511 ! chromatin remodeling GO:0006338 109 51 0,000 0,03497695 0,03941664 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,03497695 0,03939819 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,03497695 0,03937975 ! vesicle organization GO:0016050 107 51 0,000 0,03497695 0,03936133 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,03497695 0,03934293 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 0,000 0,03497695 0,03932455 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,03497695 0,03930618 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,03565098 0,04004494 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,03565098 0,04002625 ! membrane fusion GO:0006944 110 52 0,000 0,03565098 0,04000758 ! positive regulation of growth GO:0045927 90 52 0,000 0,03565098 0,03998893 ! covalent chromatin modification GO:0016569 101 52 0,000 0,03565098 0,0399703 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,03565098 0,03995168 ! amino acid activation GO:0043038 92 52 0,000 0,03565098 0,03993308 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,03565098 0,0399145 ! synapse organization GO:0050808 85 52 0,000 0,03565098 0,03989593 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,03632456 0,04063082 ! RNA catabolic process GO:0006401 93 53 0,000 0,03632456 0,04061194 ! regulation of translational initiation GO:0006446 82 53 0,000 0,03632456 0,04059308 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,03632456 0,04057423 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,03632456 0,04055541 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,03632456 0,0405366 ! cell maturation GO:0048469 100 53 0,000 0,03632456 0,0405178 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,03632456 0,04049903 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,03632456 0,04048027 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,0369977 0,04121133 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,0369977 0,04119226 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,0369977 0,0411732 ! cell recognition GO:0008037 85 54 0,000 0,0369977 0,04115417 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,0369977 0,04113515 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,0369977 0,04111615 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,0369977 0,04109717 ! chloride transport GO:0006821 90 55 0,000 0,03767039 0,04182508 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,03767039 0,04180579 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,03767039 0,04178652 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,03767039 0,04176726 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,03767039 0,04174802 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,03767039 0,0417288 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,03767039 0,0417096 ! aging GO:0007568 103 55 0,000 0,03767039 0,04169041 ! gastrulation GO:0007369 112 55 0,000 0,03767039 0,04167125 ! heart morphogenesis GO:0003007 97 55 0,000 0,03767039 0,04165209 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,03767039 0,04163296 ! RNA elongation GO:0006354 79 55 0,000 0,03767039 0,04161385 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,03767039 0,04159475 ! regulation of actin filament length GO:0030832 105 56 0,000 0,03834263 0,0423176 ! sensory perception of smell GO:0007608 80 56 0,000 0,03834263 0,0422982 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,03834263 0,04227881 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,03834263 0,04225945 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,03834263 0,0422401 ! regulation of DNA replication GO:0006275 101 56 0,000 0,03834263 0,04222076 ! proton transport GO:0015992 94 56 0,000 0,03834263 0,04220145 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,03901443 0,04292122 ! muscle fiber development GO:0048747 112 57 0,000 0,03901443 0,0429016 ! positive regulation of cell migration GO:0030335 126 57 0,000 0,03901443 0,042882 ! lipid modification GO:0030258 97 57 0,000 0,03901443 0,04286242 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,03901443 0,04284286 ! regulation of intracellular transport GO:0032386 101 57 0,000 0,03901443 0,04282332 ! maintenance of location GO:0051235 118 57 0,000 0,03901443 0,04280379 ! hydrogen transport GO:0006818 97 58 0,000 0,03968577 0,0435205 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,03968577 0,04350067 ! regulation of endocytosis GO:0030100 91 58 0,000 0,03968577 0,04348086 ! adult behavior GO:0030534 99 58 0,000 0,03968577 0,04346107 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,03968577 0,0434413 ! positive regulation of secretion GO:0051047 95 59 0,000 0,04035667 0,0441556 ! regulation of cellular component size GO:0032535 109 59 0,000 0,04035667 0,04413553 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,04035667 0,04411547 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,04035667 0,04409544 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,04035667 0,04407542 ! DNA catabolic process GO:0006308 86 59 0,000 0,04035667 0,04405542 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,04035667 0,04403544 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,04102713 0,04474672 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,04102713 0,04472645 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,04102713 0,04470619 ! regulation of heart contraction GO:0008016 110 60 0,000 0,04102713 0,04468595 ! camera-type eye development GO:0043010 116 60 0,000 0,04102713 0,04466573 ! protein amino acid autophosphorylation GO:0046777 141 60 0,000 0,04102713 0,04464553 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,04102713 0,04462535 ! kidney development GO:0001822 122 60 0,000 0,04102713 0,04460518 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,04169714 0,04531315 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,04169714 0,04529269 ! mesoderm development GO:0007498 119 61 0,000 0,04169714 0,04527225 ! tRNA processing GO:0008033 89 61 0,000 0,04169714 0,04525183 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,04169714 0,04523143 ! ear development GO:0043583 103 62 0,000 0,0423667 0,04593703 ! viral reproductive process GO:0022415 126 62 0,000 0,0423667 0,04591634 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,0423667 0,04589567 ! gonad development GO:0008406 98 62 0,000 0,0423667 0,04587501 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,0423667 0,04585437 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,04303581 0,04655763 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,04303581 0,0465367 ! detection of external stimulus GO:0009581 91 63 0,000 0,04303581 0,0465158 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,04303581 0,04649491 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,04303581 0,04647404 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,04370449 0,04717496 ! cell redox homeostasis GO:0045454 102 64 0,000 0,04370449 0,04715381 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,04370449 0,04713267 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,04370449 0,04711156 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,04370449 0,04709046 ! positive regulation of cell motion GO:0051272 146 64 0,000 0,04370449 0,04706938 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,04437271 0,04776767 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,04437271 0,04774631 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,04437271 0,04772496 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,04437271 0,04770364 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,04437271 0,04768233 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,04504049 0,04837832 ! actin filament organization GO:0007015 148 66 0,000 0,04504049 0,04835673 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,04504049 0,04833516 ! extracellular matrix organization GO:0030198 133 66 0,000 0,04504049 0,04831361 ! secondary metabolic process GO:0019748 116 66 0,000 0,04504049 0,04829208 ! developmental maturation GO:0021700 116 66 0,000 0,04504049 0,04827057 ! cell projection assembly GO:0030031 120 66 0,000 0,04504049 0,04824908 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,04570783 0,04894216 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,04570783 0,04892039 ! negative regulation of protein kinase activity GO:0006469 130 67 0,000 0,04570783 0,04889864 ! negative regulation of cell growth GO:0030308 132 67 0,000 0,04570783 0,04887691 ! activation of MAPK activity GO:0000187 115 67 0,000 0,04570783 0,04885519 ! lung development GO:0030324 144 67 0,000 0,04570783 0,0488335 ! chromosome segregation GO:0007059 113 67 0,000 0,04570783 0,04881182 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,04570783 0,04879017 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,04570783 0,04876853 ! hexose catabolic process GO:0019320 104 67 0,000 0,04570783 0,04874691 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,04570783 0,04872532 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,04570783 0,04870374 ! adaptive immune response GO:0002250 119 67 0,000 0,04570783 0,04868218 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,04570783 0,04866064 ! amino acid transport GO:0006865 125 68 0,000 0,04637472 0,04934878 ! negative regulation of kinase activity GO:0033673 131 68 0,000 0,04637472 0,04932696 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,04637472 0,04930516 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,04637472 0,04928339 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,04637472 0,04926163 ! viral reproduction GO:0016032 134 68 0,000 0,04637472 0,04923989 ! regulation of lipase activity GO:0060191 130 68 0,000 0,04637472 0,04921817 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,04637472 0,04919647 ! negative regulation of cell size GO:0045792 134 69 0,000 0,04704117 0,04988147 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,04704117 0,0498595 ! urogenital system development GO:0001655 137 69 0,000 0,04704117 0,04983754 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,04704117 0,04981561 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,04704117 0,04979369 ! antigen processing and presentation GO:0019882 104 69 0,000 0,04704117 0,04977179 ! appendage morphogenesis GO:0035107 135 70 0,000 0,04770718 0,05045427 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 0,000 0,04770718 0,0504321 ! amine catabolic process GO:0009310 117 71 0,000 0,04837274 0,05111323 ! reproductive structure development GO:0048608 113 71 0,000 0,04837274 0,05109079 ! appendage development GO:0048736 136 71 0,000 0,04837274 0,05106837 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,04837274 0,05104597 ! B cell activation GO:0042113 160 71 0,000 0,04837274 0,05102359 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,04837274 0,05100123 ! regulation of immune effector process GO:0002697 137 71 0,000 0,04837274 0,05097889 ! acute inflammatory response GO:0002526 113 72 0,000 0,04903786 0,05165722 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,04903786 0,05163461 ! carbohydrate transport GO:0008643 110 72 0,000 0,04903786 0,05161203 ! negative regulation of transferase activity GO:0051348 140 72 0,000 0,04903786 0,05158946 ! respiratory system development GO:0060541 153 72 0,000 0,04903786 0,05156691 ! learning or memory GO:0007611 147 73 0,000 0,04970254 0,05224303 ! regulation of blood pressure GO:0008217 125 73 0,000 0,04970254 0,05222022 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,04970254 0,05219743 ! axon guidance GO:0007411 139 73 0,000 0,04970254 0,05217465 ! fertilization GO:0009566 90 73 0,000 0,04970254 0,0521519 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,05036677 0,05282583 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,05036677 0,05280281 ! neurotransmitter transport GO:0006836 123 74 0,000 0,05036677 0,05277981 ! meiosis GO:0007126 121 74 0,000 0,05036677 0,05275683 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,05036677 0,05273388 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,05036677 0,05271094 ! eye development GO:0001654 143 74 0,000 0,05036677 0,05268802 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,05103056 0,05335921 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,05103056 0,05333603 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,05103056 0,05331287 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,05103056 0,05328973 ! meiotic cell cycle GO:0051321 122 75 0,000 0,05103056 0,05326661 ! rhythmic process GO:0048511 128 75 0,000 0,05103056 0,05324351 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,05103056 0,05322043 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,05169391 0,05388889 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,05169391 0,05386555 ! defense response to bacterium GO:0042742 89 76 0,000 0,05169391 0,05384223 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,05169391 0,05381893 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,05169391 0,05379565 ! regulation of catabolic process GO:0009894 161 76 0,000 0,05169391 0,0537724 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,05235682 0,05443842 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,05235682 0,05441491 ! blood coagulation GO:0007596 146 78 0,000 0,05301929 0,05507962 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,05301929 0,05505585 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,05301929 0,0550321 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,05301929 0,05500837 ! protein oligomerization GO:0051259 139 78 0,000 0,05301929 0,05498466 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,05368131 0,05564724 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,05368131 0,05562327 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,05368131 0,05559933 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,05368131 0,0555754 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,0543429 0,05623613 ! muscle cell differentiation GO:0042692 159 80 0,000 0,0543429 0,05621196 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,0543429 0,0561878 ! protein import into nucleus GO:0006606 158 80 0,000 0,0543429 0,05616367 ! inorganic anion transport GO:0015698 138 80 0,000 0,0543429 0,05613955 ! T cell activation GO:0042110 168 81 0,000 0,05500404 0,05679817 ! response to hypoxia GO:0001666 171 81 0,000 0,05500404 0,0567738 ! digestion GO:0007586 112 81 0,000 0,05500404 0,05674945 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,05500404 0,05672513 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,05500404 0,05670083 ! nuclear import GO:0051170 161 81 0,000 0,05500404 0,05667654 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,05500404 0,05665228 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,05566475 0,05730825 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,05566475 0,05728374 ! response to drug GO:0042493 143 82 0,000 0,05566475 0,05725925 ! response to nutrient GO:0007584 125 82 0,000 0,05566475 0,05723478 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,05566475 0,05721033 ! cellular response to hormone stimulus GO:0032870 167 82 0,000 0,05566475 0,0571859 ! response to oxygen levels GO:0070482 176 83 0,000 0,05632501 0,05783951 ! regulation of lyase activity GO:0051339 160 83 0,000 0,05632501 0,05781484 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,05698484 0,05846717 ! hemostasis GO:0007599 158 84 0,000 0,05698484 0,05844225 ! negative regulation of transport GO:0051051 153 84 0,000 0,05698484 0,05841735 ! negative regulation of growth GO:0045926 155 84 0,000 0,05698484 0,05839247 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,05698484 0,05836761 ! nucleosome assembly GO:0006334 122 85 0,000 0,05764422 0,05901787 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,05764422 0,05899277 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,05764422 0,05896769 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,05830317 0,05961641 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,05830317 0,05959109 ! chromatin assembly GO:0031497 124 86 0,000 0,05830317 0,05956578 ! tube morphogenesis GO:0035239 176 86 0,000 0,05830317 0,0595405 ! alcohol catabolic process GO:0046164 130 86 0,000 0,05830317 0,05951524 ! amine transport GO:0015837 155 86 0,000 0,05830317 0,05949 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,05896167 0,06013641 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,05896167 0,06011093 ! protein localization in nucleus GO:0034504 176 87 0,000 0,05896167 0,06008547 ! regulation of protein transport GO:0051223 154 87 0,000 0,05896167 0,06006003 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 135 88 0,000 0,05961974 0,06070466 ! regulation of DNA binding GO:0051101 155 88 0,000 0,05961974 0,06067898 ! gland development GO:0048732 206 88 0,000 0,05961974 0,06065332 ! regulation of neurological system process GO:0031644 148 88 0,000 0,05961974 0,06062769 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,05961974 0,06060207 ! cellular defense response GO:0006968 114 89 0,000 0,06027737 0,06124466 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,06027737 0,06121881 ! ossification GO:0001503 188 90 0,000 0,06093457 0,06186015 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,06093457 0,06183406 ! sex differentiation GO:0007548 145 90 0,000 0,06093457 0,061808 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,06093457 0,06178195 ! bone development GO:0060348 189 91 0,000 0,06159132 0,06242153 ! sterol metabolic process GO:0016125 152 91 0,000 0,06159132 0,06239525 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,06159132 0,06236899 ! regulation of defense response GO:0031347 149 92 0,000 0,06224764 0,06300708 ! nucleosome organization GO:0034728 138 92 0,000 0,06224764 0,06298058 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,06224764 0,06295411 ! vitamin metabolic process GO:0006766 139 92 0,000 0,06224764 0,06292765 ! positive regulation of MAP kinase activity GO:0043406 160 93 0,000 0,06290352 0,06356399 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,06290352 0,06353731 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,06290352 0,06351064 ! regulation of membrane potential GO:0042391 164 93 0,000 0,06290352 0,063484 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,06290352 0,06345739 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,06355896 0,06409173 ! female pregnancy GO:0007565 164 94 0,000 0,06355896 0,06406488 ! transcription initiation GO:0006352 153 94 0,000 0,06355896 0,06403805 ! regulation of T cell activation GO:0050863 158 94 0,000 0,06355896 0,06401124 ! forebrain development GO:0030900 188 95 0,000 0,06421397 0,06464385 ! leukocyte differentiation GO:0002521 202 96 0,000 0,06486854 0,06527549 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,06486854 0,0652482 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,06486854 0,06522094 ! positive regulation of immune response GO:0050778 156 96 0,000 0,06486854 0,06519369 ! detection of stimulus GO:0051606 151 96 0,000 0,06486854 0,06516647 ! regulation of DNA metabolic process GO:0051052 178 97 0,000 0,06552267 0,06579614 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,06552267 0,06576869 ! hormone metabolic process GO:0042445 157 97 0,000 0,06552267 0,06574126 ! regulation of protein localization GO:0032880 176 97 0,000 0,06552267 0,06571386 ! response to virus GO:0009615 160 98 0,000 0,06617637 0,06634181 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,06617637 0,06631418 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,06617637 0,06628657 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,06682963 0,06691307 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,06682963 0,06688523 ! skeletal muscle tissue development GO:0007519 186 99 0,000 0,06682963 0,06685742 GO:0060538|skeletal muscle organ development, ! cell cycle arrest GO:0007050 213 100 0,000 0,06748246 0,06748246