pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-b2/out-0.05-06-0.01-300-run-b2//th1-pval-1e-01-06-th2-pval-1e-02-02-th3-pval-1e-01-01-run-b2/go_data/23139-2-real-IPC-NIBC-129-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! spindle assembly GO:0051225 6 5 3,000 4,499E-13 1,099E-09 ! natural killer cell mediated immunity GO:0002228 19 10 3,000 1,886E-11 2,304E-08 GO:0042267|natural killer cell mediated cytotoxicity, ! leukocyte mediated cytotoxicity GO:0001909 28 12 3,000 4,442E-11 3,617E-08 ! cell killing GO:0001906 32 15 3,000 1,223E-10 7,472E-08 ! polyol catabolic process GO:0046174 9 5 2,000 1,776E-09 8,677E-07 GO:0019405|alditol catabolic process, ! spindle organization GO:0007051 50 32 3,000 3,202E-09 1,304E-06 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 2,000 3,55E-09 1,239E-06 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 3,000 3,484E-08 1,064E-05 ! regulation of interleukin-12 production GO:0032655 19 12 2,000 3,897E-08 1,058E-05 ! cellular carbohydrate catabolic process GO:0044275 17 13 2,000 5,064E-08 1,237E-05 ! lymphocyte mediated immunity GO:0002449 122 65 3,000 5,953E-08 1,322E-05 ! fructose metabolic process GO:0006000 25 16 2,000 9,903E-08 2,016E-05 ! leukocyte mediated immunity GO:0002443 136 75 3,000 1,065E-07 2,001E-05 ! alditol metabolic process GO:0019400 44 26 2,000 4,581E-07 7,993E-05 ! sperm motility GO:0030317 37 28 2,000 5,767E-07 9,393E-05 ! hexose biosynthetic process GO:0019319 53 32 2,000 8,718E-07 1,331E-04 ! monosaccharide biosynthetic process GO:0046364 57 36 2,000 1,253E-06 1,801E-04 ! spermatid differentiation GO:0048515 73 41 2,000 1,867E-06 2,534E-04 ! alcohol biosynthetic process GO:0046165 65 42 2,000 2,01E-06 2,585E-04 ! polyol metabolic process GO:0019751 77 45 2,000 2,482E-06 3,032E-04 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 2,000 2,654E-06 3,088E-04 ! regulation of cytokine biosynthetic process GO:0042035 108 66 2,000 7,94E-06 8,817E-04 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 9,289E-06 9,866E-04 ! alcohol catabolic process GO:0046164 142 87 2,000 1,825E-05 1,857E-03 ! carbohydrate biosynthetic process GO:0016051 158 94 2,000 2,301E-05 2,249E-03 ! interphase of mitotic cell cycle GO:0051329 224 98 2,000 2,607E-05 2,45E-03 ! cellular response to unfolded protein GO:0034620 35 20 1,000 6,276E-05 5,679E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! activation of pro-apoptotic gene products GO:0008633 51 23 1,000 8,348E-05 7,284E-03 ! negative regulation of phosphorylation GO:0042326 52 24 1,000 9,104E-05 7,669E-03 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 1,000 1,071E-04 8,724E-03 GO:0045936|negative regulation of phosphate metabolic process, ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 1,071E-04 8,442E-03 ! fat cell differentiation GO:0045444 57 28 1,000 1,245E-04 9,505E-03 ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 1,337E-04 9,897E-03 ! female gamete generation GO:0007292 71 45 1,000 3,241E-04 0,02328924 ! positive regulation of cell cycle GO:0045787 96 48 1,000 3,689E-04 0,02574994 ! response to calcium ion GO:0051592 94 49 1,000 3,845E-04 0,02609068 ! response to UV GO:0009411 120 55 1,000 4,845E-04 0,0319873 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 1,000 7,397E-04 0,04755687 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 1,000 7,615E-04 0,04770369 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 1,000 8,288E-04 0,05062042 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 1,000 8,288E-04 0,04938578 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 1,000 8,752E-04 0,0509086 ! positive regulation of ligase activity GO:0051351 130 77 1,000 9,471E-04 0,05380939 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 1,000 9,966E-04 0,05533274 ! steroid biosynthetic process GO:0006694 146 79 1,000 9,966E-04 0,05410313 ! positive regulation of phosphorylation GO:0042327 149 81 1,000 1,047E-03 0,05561876 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 1,099E-03 0,05713329 GO:0045937|positive regulation of phosphate metabolic process, ! response to metal ion GO:0010038 158 84 1,000 1,126E-03 0,05728709 ! regulation of ligase activity GO:0051340 147 84 1,000 1,126E-03 0,05611796 ! response to inorganic substance GO:0010035 173 90 1,000 1,29E-03 0,0630487 ! positive regulation of protein modification process GO:0031401 156 90 1,000 1,29E-03 0,06181245 ! response to unfolded protein GO:0006986 139 90 1,000 1,29E-03 0,06062375 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 1,000 1,377E-03 0,06346658 GO:0010498|proteasomal protein catabolic process, ! response to protein stimulus GO:0051789 158 96 1,000 1,466E-03 0,06632663 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 2,951E-03 0,1310675 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 2,951E-03 0,12872701 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 2,951E-03 0,12646864 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 2,951E-03 0,12428814 ! positive regulation of helicase activity GO:0051096 12 5 0,000 2,951E-03 0,12218157 ! neuron fate determination GO:0048664 7 5 0,000 2,951E-03 0,12014521 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 2,951E-03 0,11817561 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 2,951E-03 0,11626955 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 2,951E-03 0,11442401 ! polyol transport GO:0015791 12 5 0,000 2,951E-03 0,11263613 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 2,951E-03 0,11090327 ! response to superoxide GO:0000303 10 5 0,000 2,951E-03 0,10922291 ! negative regulation of bone resorption GO:0045779 10 5 0,000 2,951E-03 0,10759272 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 2,951E-03 0,10601048 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 2,951E-03 0,10447409 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 2,951E-03 0,10298161 ! female meiosis GO:0007143 10 5 0,000 2,951E-03 0,10153116 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 2,951E-03 0,10012101 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 2,951E-03 0,09874948 ! hypothalamus development GO:0021854 9 5 0,000 2,951E-03 0,09741503 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 2,951E-03 0,09611617 ! cobalt ion transport GO:0006824 11 5 0,000 2,951E-03 0,09485148 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 2,951E-03 0,09361964 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 2,951E-03 0,09241939 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 2,951E-03 0,09124952 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 2,951E-03 0,0901089 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 2,951E-03 0,08899645 ! embryonic camera-type eye development GO:0031076 12 5 0,000 2,951E-03 0,08791113 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 2,951E-03 0,08685196 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 2,951E-03 0,085818 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 2,951E-03 0,08480838 ! transposition GO:0032196 9 5 0,000 2,951E-03 0,08382224 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 2,951E-03 0,08285876 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 2,951E-03 0,08191719 ! negative chemotaxis GO:0050919 16 5 0,000 2,951E-03 0,08099677 ! positive regulation of histone modification GO:0031058 6 5 0,000 2,951E-03 0,0800968 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 2,951E-03 0,07921662 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 2,951E-03 0,07835557 ! behavioral response to pain GO:0048266 10 5 0,000 2,951E-03 0,07751304 ! clathrin coat assembly GO:0048268 15 5 0,000 2,951E-03 0,07668843 ! Notch receptor processing GO:0007220 11 5 0,000 2,951E-03 0,07588118 ! regulation of dopamine uptake GO:0051584 9 5 0,000 2,951E-03 0,07509075 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 2,951E-03 0,07431662 ! micturition GO:0060073 9 5 0,000 2,951E-03 0,07355829 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 2,951E-03 0,07281528 ! copulation GO:0007620 9 5 0,000 2,951E-03 0,07208712 ! glial cell fate commitment GO:0021781 14 5 0,000 2,951E-03 0,07137339 ! protein maturation by protein folding GO:0022417 14 5 0,000 2,951E-03 0,07067365 ! bioluminescence GO:0008218 9 5 0,000 2,951E-03 0,0699875 ! spermidine metabolic process GO:0008216 7 5 0,000 2,951E-03 0,06931454 ! regulation of potassium ion transport GO:0043266 10 5 0,000 2,951E-03 0,0686544 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 2,951E-03 0,06800672 ! apoptotic cell clearance GO:0043277 23 5 0,000 2,951E-03 0,06737114 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 2,951E-03 0,06674734 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 2,951E-03 0,06613498 ! lipoprotein particle clearance GO:0034381 10 5 0,000 2,951E-03 0,06553375 ! grooming behavior GO:0007625 6 5 0,000 2,951E-03 0,06494335 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 2,951E-03 0,0643635 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 2,951E-03 0,06379391 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 2,951E-03 0,06323432 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 2,951E-03 0,06268446 ! response to protozoan GO:0001562 13 5 0,000 2,951E-03 0,06214407 ! positive regulation of glycolysis GO:0045821 13 5 0,000 2,951E-03 0,06161293 ! lymph vessel development GO:0001945 10 5 0,000 2,951E-03 0,06109078 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 2,951E-03 0,06057741 ! endochondral ossification GO:0001958 17 5 0,000 2,951E-03 0,0600726 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 2,951E-03 0,05957614 ! single strand break repair GO:0000012 8 5 0,000 2,951E-03 0,05908781 ! parathyroid gland development GO:0060017 14 5 0,000 2,951E-03 0,05860742 ! anagen GO:0042640 7 5 0,000 2,951E-03 0,05813478 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 2,951E-03 0,0576697 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 2,951E-03 0,057212 ! cytokine secretion GO:0050663 15 5 0,000 2,951E-03 0,05676151 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 2,951E-03 0,05631807 ! ceramide catabolic process GO:0046514 7 5 0,000 2,951E-03 0,05588149 ! skeletal myofibril assembly GO:0014866 12 5 0,000 2,951E-03 0,05545163 ! smooth muscle tissue development GO:0048745 32 5 0,000 2,951E-03 0,05502834 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 2,951E-03 0,05461146 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 2,951E-03 0,05420084 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 2,951E-03 0,05379636 ! cardiac muscle fiber development GO:0048739 12 5 0,000 2,951E-03 0,05339787 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 2,951E-03 0,05300524 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 2,951E-03 0,05261834 ! neutrophil mediated immunity GO:0002446 7 5 0,000 2,951E-03 0,05223705 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 2,951E-03 0,05186124 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 2,951E-03 0,0514908 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 2,951E-03 0,05112562 ! glycine biosynthetic process GO:0006545 7 5 0,000 2,951E-03 0,05076558 ! microvillus organization GO:0032528 8 5 0,000 2,951E-03 0,05041058 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 2,951E-03 0,0500605 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 2,951E-03 0,04971526 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 2,951E-03 0,04937474 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 2,951E-03 0,04903886 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 2,951E-03 0,04870752 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 2,951E-03 0,04838062 ! polyol biosynthetic process GO:0046173 6 5 0,000 2,951E-03 0,04805808 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 2,951E-03 0,04773982 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 2,951E-03 0,04742574 ! muscle cell migration GO:0014812 8 5 0,000 2,951E-03 0,04711577 ! mitochondrial fission GO:0000266 8 5 0,000 2,951E-03 0,04680982 ! sister chromatid cohesion GO:0007062 15 5 0,000 2,951E-03 0,04650782 ! response to tumor necrosis factor GO:0034612 10 5 0,000 2,951E-03 0,04620969 ! mRNA transcription GO:0009299 10 5 0,000 2,951E-03 0,04591537 ! nerve growth factor processing GO:0032455 9 5 0,000 2,951E-03 0,04562476 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 2,951E-03 0,04533781 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 2,951E-03 0,04505445 ! anaerobic glycolysis GO:0019642 6 5 0,000 2,951E-03 0,04477461 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 2,951E-03 0,04449822 ! monocyte activation GO:0042117 10 5 0,000 2,951E-03 0,04422523 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 2,951E-03 0,04395556 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 2,951E-03 0,04368917 ! response to food GO:0032094 6 5 0,000 2,951E-03 0,04342598 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 2,951E-03 0,04316594 ! positive regulation of transporter activity GO:0032411 8 5 0,000 2,951E-03 0,042909 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 2,951E-03 0,0426551 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 2,951E-03 0,04240419 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 2,951E-03 0,04215621 ! forebrain neuron development GO:0021884 13 5 0,000 2,951E-03 0,04191112 ! lipoprotein catabolic process GO:0042159 11 5 0,000 2,951E-03 0,04166886 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 2,951E-03 0,04142938 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 2,951E-03 0,04119264 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 2,951E-03 0,04095859 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 2,951E-03 0,04072719 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 2,951E-03 0,04049838 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 2,951E-03 0,04027214 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 2,951E-03 0,0400484 ! lipid glycosylation GO:0030259 7 5 0,000 2,951E-03 0,03982714 ! nucleobase transport GO:0015851 6 5 0,000 2,951E-03 0,03960831 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 2,951E-03 0,03939187 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 2,951E-03 0,03917778 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 2,951E-03 0,03896601 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 2,951E-03 0,03875652 ! basic amino acid transport GO:0015802 12 5 0,000 2,951E-03 0,03854926 ! cellular glucose homeostasis GO:0001678 6 5 0,000 2,951E-03 0,03834421 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 2,951E-03 0,03814134 ! actin nucleation GO:0045010 11 5 0,000 2,951E-03 0,03794059 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 2,951E-03 0,03774195 ! depurination GO:0045007 5 5 0,000 2,951E-03 0,03754538 ! depyrimidination GO:0045008 10 5 0,000 2,951E-03 0,03735084 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 2,951E-03 0,03715831 ! regulation of centrosome cycle GO:0046605 7 5 0,000 2,951E-03 0,03696776 ! G2/M transition checkpoint GO:0031576 8 5 0,000 2,951E-03 0,03677914 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 2,951E-03 0,03659245 ! zinc ion homeostasis GO:0055069 9 5 0,000 2,951E-03 0,03640764 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 2,951E-03 0,03622469 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 2,951E-03 0,03604356 ! forebrain morphogenesis GO:0048853 13 5 0,000 2,951E-03 0,03586424 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 2,951E-03 0,03568669 ! activated T cell proliferation GO:0050798 16 5 0,000 2,951E-03 0,0355109 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 2,951E-03 0,03533683 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 2,951E-03 0,03516445 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 2,951E-03 0,03499375 ! positive regulation of organ growth GO:0046622 6 5 0,000 2,951E-03 0,0348247 ! gamma-delta T cell activation GO:0046629 6 5 0,000 2,951E-03 0,03465727 ! response to arsenic GO:0046685 11 5 0,000 2,951E-03 0,03449145 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 2,951E-03 0,0343272 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 2,951E-03 0,03416451 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 2,951E-03 0,03400336 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 2,951E-03 0,03384372 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 2,951E-03 0,03368557 ! response to mercury ion GO:0046689 8 5 0,000 2,951E-03 0,03352889 ! response to cadmium ion GO:0046686 7 5 0,000 2,951E-03 0,03337367 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 2,951E-03 0,03321987 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 2,951E-03 0,03306749 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 2,951E-03 0,03291649 ! bile acid biosynthetic process GO:0006699 7 5 0,000 2,951E-03 0,03276687 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 2,951E-03 0,03261861 ! ganglioside catabolic process GO:0006689 12 5 0,000 2,951E-03 0,03247168 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 2,951E-03 0,03232606 ! decidualization GO:0046697 11 5 0,000 2,951E-03 0,03218175 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 2,951E-03 0,03203872 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 2,951E-03 0,03189696 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 2,951E-03 0,03175644 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 2,951E-03 0,03161716 ! embryonic cleavage GO:0040016 6 5 0,000 2,951E-03 0,03147909 ! peroxisome fission GO:0016559 5 5 0,000 2,951E-03 0,03134223 ! histone demethylation GO:0016577 13 5 0,000 2,951E-03 0,03120655 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 2,951E-03 0,03107204 ! mitotic recombination GO:0006312 9 5 0,000 2,951E-03 0,03093868 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 2,951E-03 0,03080646 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 2,951E-03 0,03067537 ! metaphase plate congression GO:0051310 7 5 0,000 2,951E-03 0,03054539 ! regulation of sterol transport GO:0032371 7 5 0,000 2,951E-03 0,03041651 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 2,951E-03 0,03028871 ! enteric nervous system development GO:0048484 8 5 0,000 2,951E-03 0,03016198 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 2,951E-03 0,0300363 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 2,951E-03 0,02991167 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 2,951E-03 0,02978807 ! muscle cell proliferation GO:0033002 12 5 0,000 2,951E-03 0,02966548 ! skeletal muscle regeneration GO:0043403 8 5 0,000 2,951E-03 0,0295439 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 2,951E-03 0,02942332 ! B cell homeostasis GO:0001782 13 5 0,000 2,951E-03 0,02930371 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 2,951E-03 0,02918507 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 2,951E-03 0,02906739 ! metaphase GO:0051323 11 5 0,000 2,951E-03 0,02895065 ! melatonin biosynthetic process GO:0030187 7 5 0,000 2,951E-03 0,02883485 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 2,951E-03 0,02871997 ! cellular response to nutrient GO:0031670 8 5 0,000 2,951E-03 0,028606 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 2,951E-03 0,02849293 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 2,951E-03 0,02838076 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 2,951E-03 0,02826946 ! regulation of hair follicle development GO:0051797 10 5 0,000 2,951E-03 0,02815903 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 2,951E-03 0,02804946 ! response to redox state GO:0051775 6 5 0,000 2,951E-03 0,02794075 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 2,951E-03 0,02783287 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 2,951E-03 0,02772582 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 2,951E-03 0,02761959 ! brown fat cell differentiation GO:0050873 7 5 0,000 2,951E-03 0,02751417 ! regulation of telomerase activity GO:0051972 7 5 0,000 2,951E-03 0,02740955 ! galactolipid metabolic process GO:0019374 7 5 0,000 2,951E-03 0,02730573 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 2,951E-03 0,02720269 ! porphyrin catabolic process GO:0006787 12 5 0,000 2,951E-03 0,02710042 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 2,951E-03 0,02699892 ! striatum development GO:0021756 14 5 0,000 2,951E-03 0,02689818 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 2,951E-03 0,02679819 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 2,951E-03 0,02669893 ! glial cell migration GO:0008347 10 5 0,000 2,951E-03 0,02660041 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 2,951E-03 0,02650262 ! neural plate morphogenesis GO:0001839 7 5 0,000 2,951E-03 0,02640554 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 2,951E-03 0,02630917 ! somatic stem cell maintenance GO:0035019 15 5 0,000 2,951E-03 0,0262135 ! T cell activation during immune response GO:0002286 9 5 0,000 2,951E-03 0,02611852 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 2,951E-03 0,02602423 ! negative regulation of lipase activity GO:0060192 8 5 0,000 2,951E-03 0,02593062 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 2,951E-03 0,02583768 ! neuroprotection GO:0043526 8 5 0,000 2,951E-03 0,0257454 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 2,951E-03 0,02565378 ! regulation of sensory perception GO:0051931 8 5 0,000 2,951E-03 0,02556281 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 2,951E-03 0,02547248 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 2,951E-03 0,02538279 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 2,951E-03 0,02529373 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 2,951E-03 0,02520529 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 2,951E-03 0,02511746 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 2,951E-03 0,02503025 ! sequestering of calcium ion GO:0051208 7 5 0,000 2,951E-03 0,02494364 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 2,951E-03 0,02485763 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 2,951E-03 0,02477221 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 2,951E-03 0,02468737 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 2,951E-03 0,02460311 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 2,951E-03 0,02451943 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 2,951E-03 0,02443631 ! protein palmitoylation GO:0018345 12 5 0,000 2,951E-03 0,02435376 ! drug metabolic process GO:0017144 7 5 0,000 2,951E-03 0,02427176 ! stem cell division GO:0017145 11 5 0,000 2,951E-03 0,02419031 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 2,951E-03 0,02410941 ! organ regeneration GO:0031100 7 5 0,000 2,951E-03 0,02402904 ! carnitine metabolic process GO:0009437 8 5 0,000 2,951E-03 0,02394921 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 2,951E-03 0,02386991 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 3,54E-03 0,02854133 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 3,54E-03 0,02844744 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 3,54E-03 0,02835417 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 3,54E-03 0,02826151 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 3,54E-03 0,02816945 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 3,54E-03 0,02807799 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 3,54E-03 0,02798713 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 3,54E-03 0,02789684 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 3,54E-03 0,02780714 ! response to oxygen radical GO:0000305 11 6 0,000 3,54E-03 0,02771802 ! positive regulation of axon extension GO:0045773 13 6 0,000 3,54E-03 0,02762946 ! myoblast cell fate commitment GO:0048625 18 6 0,000 3,54E-03 0,02754147 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 3,54E-03 0,02745404 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 3,54E-03 0,02736716 ! regulation of interferon-beta production GO:0032648 8 6 0,000 3,54E-03 0,02728083 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 3,54E-03 0,02719504 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 3,54E-03 0,02710979 ! forebrain regionalization GO:0021871 9 6 0,000 3,54E-03 0,02702507 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 3,54E-03 0,02694088 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 3,54E-03 0,02685721 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 3,54E-03 0,02677406 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 3,54E-03 0,02669143 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 3,54E-03 0,0266093 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 3,54E-03 0,02652767 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 3,54E-03 0,02644655 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 3,54E-03 0,02636592 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 3,54E-03 0,02628578 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 3,54E-03 0,02620613 ! malate metabolic process GO:0006108 13 6 0,000 3,54E-03 0,02612695 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 3,54E-03 0,02604826 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 3,54E-03 0,02597004 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 3,54E-03 0,02589228 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 3,54E-03 0,02581499 ! protein refolding GO:0042026 15 6 0,000 3,54E-03 0,02573816 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 3,54E-03 0,02566179 ! opsonization GO:0008228 8 6 0,000 3,54E-03 0,02558586 ! mating behavior GO:0007617 7 6 0,000 3,54E-03 0,02551039 ! erythrocyte maturation GO:0043249 8 6 0,000 3,54E-03 0,02543536 ! embryonic hemopoiesis GO:0035162 16 6 0,000 3,54E-03 0,02536077 ! protein amino acid dealkylation GO:0008214 15 6 0,000 3,54E-03 0,02528661 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 3,54E-03 0,02521289 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 3,54E-03 0,0251396 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 3,54E-03 0,02506673 ! response to interferon-gamma GO:0034341 16 6 0,000 3,54E-03 0,02499428 ! toxin metabolic process GO:0009404 11 6 0,000 3,54E-03 0,02492225 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 3,54E-03 0,02485064 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 3,54E-03 0,02477943 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 3,54E-03 0,02470863 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 3,54E-03 0,02463824 ! cGMP-mediated signaling GO:0019934 14 6 0,000 3,54E-03 0,02456824 ! dorsal spinal cord development GO:0021516 10 6 0,000 3,54E-03 0,02449865 ! activation of MAPKKK activity GO:0000185 12 6 0,000 3,54E-03 0,02442944 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 3,54E-03 0,02436062 ! thymic T cell selection GO:0045061 16 6 0,000 3,54E-03 0,0242922 ! sphingoid catabolic process GO:0046521 8 6 0,000 3,54E-03 0,02422415 ! protein lipoylation GO:0009249 10 6 0,000 3,54E-03 0,02415649 ! transepithelial chloride transport GO:0030321 12 6 0,000 3,54E-03 0,0240892 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 3,54E-03 0,02402228 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 3,54E-03 0,02395574 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 3,54E-03 0,02388956 ! glutamate catabolic process GO:0006538 12 6 0,000 3,54E-03 0,02382375 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 3,54E-03 0,0237583 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 3,54E-03 0,02369321 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 3,54E-03 0,02362847 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 3,54E-03 0,02356409 ! hyperosmotic response GO:0006972 10 6 0,000 3,54E-03 0,02350006 ! L-serine biosynthetic process GO:0006564 7 6 0,000 3,54E-03 0,02343637 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 3,54E-03 0,02337303 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 3,54E-03 0,02331003 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 3,54E-03 0,02324737 ! urea metabolic process GO:0019627 7 6 0,000 3,54E-03 0,02318505 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 3,54E-03 0,02312305 ! neutrophil activation GO:0042119 7 6 0,000 3,54E-03 0,02306139 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 3,54E-03 0,02300006 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 3,54E-03 0,02293905 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 3,54E-03 0,02287836 ! paraxial mesoderm development GO:0048339 16 6 0,000 3,54E-03 0,022818 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 3,54E-03 0,02275795 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 3,54E-03 0,02269822 ! neuron apoptosis GO:0051402 15 6 0,000 3,54E-03 0,0226388 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 3,54E-03 0,02257969 ! T cell mediated immunity GO:0002456 17 6 0,000 3,54E-03 0,02252089 ! negative regulation of platelet activation GO:0010544 9 6 0,000 3,54E-03 0,02246239 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 3,54E-03 0,0224042 ! carnitine transport GO:0015879 10 6 0,000 3,54E-03 0,02234631 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 3,54E-03 0,02228872 ! positive regulation of exocytosis GO:0045921 11 6 0,000 3,54E-03 0,02223142 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 3,54E-03 0,02217441 ! early endosome to late endosome transport GO:0045022 16 6 0,000 3,54E-03 0,0221177 ! 5S class rRNA transcription GO:0042791 13 6 0,000 3,54E-03 0,02206128 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 3,54E-03 0,02200514 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 3,54E-03 0,02194929 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 3,54E-03 0,02189373 ! sodium ion homeostasis GO:0055078 12 6 0,000 3,54E-03 0,02183844 ! establishment of spindle localization GO:0051293 16 6 0,000 3,54E-03 0,02178343 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 3,54E-03 0,0217287 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 3,54E-03 0,02167424 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 3,54E-03 0,02162005 ! response to UV-C GO:0010225 14 6 0,000 3,54E-03 0,02156614 ! astrocyte development GO:0014002 16 6 0,000 3,54E-03 0,02151249 ! protein targeting to lysosome GO:0006622 12 6 0,000 3,54E-03 0,02145911 ! purine base biosynthetic process GO:0009113 17 6 0,000 3,54E-03 0,02140599 ! interaction with symbiont GO:0051702 14 6 0,000 3,54E-03 0,02135314 ! regulation of dendrite development GO:0050773 16 6 0,000 3,54E-03 0,02130055 ! peptidyl-arginine modification GO:0018195 13 6 0,000 3,54E-03 0,02124821 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 3,54E-03 0,02119613 ! response to copper ion GO:0046688 10 6 0,000 3,54E-03 0,02114431 ! response to exogenous dsRNA GO:0043330 13 6 0,000 3,54E-03 0,02109274 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 3,54E-03 0,02104142 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 3,54E-03 0,02099034 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 3,54E-03 0,02093952 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 3,54E-03 0,02088894 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 3,54E-03 0,02083861 ! regulation of dopamine secretion GO:0014059 14 6 0,000 3,54E-03 0,02078851 ! nucleoside catabolic process GO:0009164 10 6 0,000 3,54E-03 0,02073866 ! hair follicle maturation GO:0048820 8 6 0,000 3,54E-03 0,02068905 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 3,54E-03 0,02063967 ! Schwann cell development GO:0014044 15 6 0,000 3,54E-03 0,02059053 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 3,54E-03 0,02054162 ! response to pheromone GO:0019236 6 6 0,000 3,54E-03 0,02049294 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 3,54E-03 0,0204445 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 3,54E-03 0,02039628 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 3,54E-03 0,02034829 ! base conversion or substitution editing GO:0016553 6 6 0,000 3,54E-03 0,02030052 ! subpallium development GO:0021544 15 6 0,000 3,54E-03 0,02025298 ! neural tube patterning GO:0021532 8 6 0,000 3,54E-03 0,02020566 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 3,54E-03 0,02015856 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 3,54E-03 0,02011168 ! maintenance of organ identity GO:0048496 9 6 0,000 3,54E-03 0,02006502 ! G2 phase GO:0051319 16 6 0,000 3,54E-03 0,02001857 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 3,54E-03 0,01997234 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 3,54E-03 0,01992632 ! oxygen homeostasis GO:0032364 10 6 0,000 3,54E-03 0,01988051 ! establishment of planar polarity GO:0001736 7 6 0,000 3,54E-03 0,01983491 ! regulation of mast cell activation GO:0033003 13 6 0,000 3,54E-03 0,01978952 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 3,54E-03 0,01974434 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 3,54E-03 0,01969937 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 3,54E-03 0,01965459 ! receptor internalization GO:0031623 11 6 0,000 3,54E-03 0,01961003 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 3,54E-03 0,01956566 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 3,54E-03 0,01952149 ! neutrophil homeostasis GO:0001780 11 6 0,000 3,54E-03 0,01947753 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 3,54E-03 0,01943376 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 3,54E-03 0,01939018 ! protein deubiquitination GO:0016579 16 6 0,000 3,54E-03 0,0193468 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 3,54E-03 0,01930362 ! protein destabilization GO:0031648 9 6 0,000 3,54E-03 0,01926063 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 3,54E-03 0,01921783 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 3,54E-03 0,01917521 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 3,54E-03 0,01913279 ! regulation of viral transcription GO:0046782 11 6 0,000 3,54E-03 0,01909056 ! progesterone metabolic process GO:0042448 12 6 0,000 3,54E-03 0,01904851 ! negative regulation of axon extension GO:0030517 24 6 0,000 3,54E-03 0,01900664 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 3,54E-03 0,01896496 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 3,54E-03 0,01892346 ! triglyceride catabolic process GO:0019433 10 6 0,000 3,54E-03 0,01888214 ! determination of adult lifespan GO:0008340 17 6 0,000 3,54E-03 0,01884101 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 3,54E-03 0,01880005 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 3,54E-03 0,01875927 ! neural plate development GO:0001840 9 6 0,000 3,54E-03 0,01871866 ! catecholamine transport GO:0051937 9 6 0,000 3,54E-03 0,01867823 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 3,54E-03 0,01863798 ! sensory cilium assembly GO:0035058 10 6 0,000 3,54E-03 0,0185979 ! organ or tissue specific immune response GO:0002251 8 6 0,000 3,54E-03 0,01855799 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 3,54E-03 0,01851825 ! maternal placenta development GO:0001893 12 6 0,000 3,54E-03 0,01847868 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 3,54E-03 0,01843928 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 3,54E-03 0,01840005 ! negative regulation of B cell activation GO:0050869 14 6 0,000 3,54E-03 0,01836098 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 3,54E-03 0,01832208 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 3,54E-03 0,01828334 ! positive regulation of coagulation GO:0050820 13 6 0,000 3,54E-03 0,01824477 ! cellular anion homeostasis GO:0030002 11 6 0,000 3,54E-03 0,01820636 GO:0055081|anion homeostasis, ! tRNA transcription GO:0009304 17 7 0,000 4,129E-03 0,02119017 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 4,129E-03 0,02114575 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 4,129E-03 0,02110151 ! behavioral response to cocaine GO:0048148 14 7 0,000 4,129E-03 0,02105746 ! regulation of helicase activity GO:0051095 16 7 0,000 4,129E-03 0,02101359 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 4,129E-03 0,0209699 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 4,129E-03 0,02092639 ! sleep GO:0030431 16 7 0,000 4,129E-03 0,02088307 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 4,129E-03 0,02083992 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 4,129E-03 0,02079695 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 4,129E-03 0,02075416 ! prostate gland development GO:0030850 14 7 0,000 4,129E-03 0,02071154 ! nucleotide-sugar transport GO:0015780 11 7 0,000 4,129E-03 0,0206691 ! synaptonemal complex assembly GO:0007130 10 7 0,000 4,129E-03 0,02062683 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 4,129E-03 0,02058474 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 4,129E-03 0,02054281 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 4,129E-03 0,02050106 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 4,129E-03 0,02045948 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 4,129E-03 0,02041806 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 4,129E-03 0,02037681 ! SMAD protein complex assembly GO:0007183 13 7 0,000 4,129E-03 0,02033573 ! glycolipid transport GO:0046836 11 7 0,000 4,129E-03 0,02029481 ! protein amino acid sulfation GO:0006477 10 7 0,000 4,129E-03 0,02025406 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 4,129E-03 0,02021347 ! neuron adhesion GO:0007158 14 7 0,000 4,129E-03 0,02017304 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 4,129E-03 0,02013278 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 4,129E-03 0,02009267 ! establishment of tissue polarity GO:0007164 8 7 0,000 4,129E-03 0,02005273 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 4,129E-03 0,02001294 ! mRNA stabilization GO:0048255 18 7 0,000 4,129E-03 0,01997331 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 4,129E-03 0,01993384 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 4,129E-03 0,01989452 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 4,129E-03 0,01985536 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 4,129E-03 0,01981635 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 4,129E-03 0,01977749 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 4,129E-03 0,01973879 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 4,129E-03 0,01970024 ! lipoprotein transport GO:0042953 14 7 0,000 4,129E-03 0,01966183 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 4,129E-03 0,01962358 ! rhythmic behavior GO:0007622 17 7 0,000 4,129E-03 0,01958548 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 4,129E-03 0,01954752 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 4,129E-03 0,01950971 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 4,129E-03 0,01947205 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 4,129E-03 0,01943453 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 4,129E-03 0,01939716 ! regulation of odontogenesis GO:0042481 14 7 0,000 4,129E-03 0,01935993 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 4,129E-03 0,01932284 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 4,129E-03 0,01928589 ! mechanosensory behavior GO:0007638 16 7 0,000 4,129E-03 0,01924909 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 4,129E-03 0,01921242 ! positive regulation of isotype switching GO:0045830 17 7 0,000 4,129E-03 0,0191759 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 4,129E-03 0,01913951 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 4,129E-03 0,01910326 ! protein-cofactor linkage GO:0018065 13 7 0,000 4,129E-03 0,01906715 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 4,129E-03 0,01903117 ! spinal cord patterning GO:0021511 14 7 0,000 4,129E-03 0,01899533 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 4,129E-03 0,01895963 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 4,129E-03 0,01892405 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 4,129E-03 0,01888862 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 4,129E-03 0,01885331 ! adrenal gland development GO:0030325 17 7 0,000 4,129E-03 0,01881814 ! cysteine metabolic process GO:0006534 13 7 0,000 4,129E-03 0,01878309 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 4,129E-03 0,01874818 ! ovulation GO:0030728 10 7 0,000 4,129E-03 0,0187134 ! adenohypophysis development GO:0021984 11 7 0,000 4,129E-03 0,01867874 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 4,129E-03 0,01864422 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 4,129E-03 0,01860982 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 4,129E-03 0,01857555 ! microtubule nucleation GO:0007020 21 7 0,000 4,129E-03 0,0185414 ! proline biosynthetic process GO:0006561 10 7 0,000 4,129E-03 0,01850738 ! tryptophan metabolic process GO:0006568 11 7 0,000 4,129E-03 0,01847348 ! thyroid hormone generation GO:0006590 13 7 0,000 4,129E-03 0,01843971 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 4,129E-03 0,01840606 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 4,129E-03 0,01837253 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 4,129E-03 0,01833913 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 4,129E-03 0,01830585 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 4,129E-03 0,01827268 ! galactose metabolic process GO:0006012 13 7 0,000 4,129E-03 0,01823964 ! vesicle fusion GO:0006906 20 7 0,000 4,129E-03 0,01820672 ! response to dietary excess GO:0002021 8 7 0,000 4,129E-03 0,01817391 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 4,129E-03 0,01814123 ! intracellular pH reduction GO:0051452 13 7 0,000 4,129E-03 0,01810866 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 4,129E-03 0,0180762 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 4,129E-03 0,01804387 ! organ growth GO:0035265 15 7 0,000 4,129E-03 0,01801164 ! nucleoside transport GO:0015858 11 7 0,000 4,129E-03 0,01797954 ! nucleoside salvage GO:0043174 11 7 0,000 4,129E-03 0,01794755 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 4,129E-03 0,01791567 ! male sex determination GO:0030238 15 7 0,000 4,129E-03 0,0178839 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 4,129E-03 0,01785225 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 4,129E-03 0,01782071 ! parturition GO:0007567 16 7 0,000 4,129E-03 0,01778928 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 4,129E-03 0,01775796 ! rRNA modification GO:0000154 14 7 0,000 4,129E-03 0,01772675 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 4,129E-03 0,01769565 ! spindle checkpoint GO:0031577 16 7 0,000 4,129E-03 0,01766466 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 4,129E-03 0,01763378 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 4,129E-03 0,017603 ! monocyte differentiation GO:0030224 16 7 0,000 4,129E-03 0,01757234 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 4,129E-03 0,01754178 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 4,129E-03 0,01751132 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 4,129E-03 0,01748097 ! hyaluronan metabolic process GO:0030212 9 7 0,000 4,129E-03 0,01745073 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 4,129E-03 0,01742059 ! anterograde axon cargo transport GO:0008089 18 7 0,000 4,129E-03 0,01739055 ! fibrinolysis GO:0042730 11 7 0,000 4,129E-03 0,01736062 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 4,129E-03 0,01733079 ! skeletal muscle contraction GO:0003009 8 7 0,000 4,129E-03 0,01730107 ! eating behavior GO:0042755 8 7 0,000 4,129E-03 0,01727144 ! B cell lineage commitment GO:0002326 21 7 0,000 4,129E-03 0,01724192 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 4,129E-03 0,01721249 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 4,129E-03 0,01718317 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 4,129E-03 0,01715395 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 4,129E-03 0,01712482 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 4,129E-03 0,0170958 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 4,129E-03 0,01706687 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 4,129E-03 0,01703804 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 4,129E-03 0,01700931 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 4,129E-03 0,01698068 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 4,129E-03 0,01695214 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 4,129E-03 0,01692369 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 4,129E-03 0,01689535 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 4,129E-03 0,01686709 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 4,129E-03 0,01683893 ! histone ubiquitination GO:0016574 9 7 0,000 4,129E-03 0,01681087 ! regulation of meiosis GO:0040020 12 7 0,000 4,129E-03 0,0167829 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 4,129E-03 0,01675502 ! T cell lineage commitment GO:0002360 16 7 0,000 4,129E-03 0,01672723 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 4,129E-03 0,01669954 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 4,129E-03 0,01667194 ! membrane to membrane docking GO:0022614 14 7 0,000 4,129E-03 0,01664442 ! transcription termination GO:0006353 14 7 0,000 4,129E-03 0,016617 ! coenzyme A metabolic process GO:0015936 12 7 0,000 4,129E-03 0,01658967 ! anaphase GO:0051322 18 7 0,000 4,129E-03 0,01656243 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 4,129E-03 0,01653528 ! axonal fasciculation GO:0007413 19 7 0,000 4,129E-03 0,01650822 ! negative regulation of nuclear division GO:0051784 15 7 0,000 4,129E-03 0,01648124 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 4,129E-03 0,01645436 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 4,129E-03 0,01642756 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 4,129E-03 0,01640085 ! diuresis GO:0030146 12 7 0,000 4,129E-03 0,01637422 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 4,129E-03 0,01634768 ! thiamin metabolic process GO:0006772 7 7 0,000 4,129E-03 0,01632123 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 4,129E-03 0,01629486 ! antibiotic transport GO:0042891 9 7 0,000 4,129E-03 0,01626858 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 4,129E-03 0,01624239 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 4,129E-03 0,01621627 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 4,129E-03 0,01619024 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 4,129E-03 0,0161643 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 4,129E-03 0,01613843 ! melanin biosynthetic process GO:0042438 10 7 0,000 4,129E-03 0,01611265 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 4,129E-03 0,01608696 ! dopamine biosynthetic process GO:0042416 18 7 0,000 4,129E-03 0,01606134 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 4,129E-03 0,0160358 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 4,129E-03 0,01601035 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 4,129E-03 0,01598498 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 4,129E-03 0,01595969 ! endosome to lysosome transport GO:0008333 12 7 0,000 4,129E-03 0,01593447 ! protein modification by small protein removal GO:0070646 19 7 0,000 4,129E-03 0,01590934 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 4,129E-03 0,01588429 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 4,129E-03 0,01585931 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 4,129E-03 0,01583441 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 4,129E-03 0,01580959 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 4,129E-03 0,01578485 ! muscle adaptation GO:0043500 13 7 0,000 4,129E-03 0,01576019 ! embryonic heart tube development GO:0035050 14 7 0,000 4,129E-03 0,0157356 ! retina homeostasis GO:0001895 12 7 0,000 4,129E-03 0,01571109 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 4,129E-03 0,01568666 ! protein amino acid prenylation GO:0018346 19 7 0,000 4,129E-03 0,0156623 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 4,129E-03 0,01563802 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 4,129E-03 0,01561381 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 4,717E-03 0,01781176 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 4,717E-03 0,01778428 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 4,717E-03 0,01775687 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 4,717E-03 0,01772956 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 4,717E-03 0,01770232 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 4,717E-03 0,01767517 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 4,717E-03 0,0176481 ! male meiosis GO:0007140 9 8 0,000 4,717E-03 0,01762112 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 4,717E-03 0,01759422 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 4,717E-03 0,01756739 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 4,717E-03 0,01754066 ! meiotic prophase I GO:0007128 14 8 0,000 4,717E-03 0,017514 ! response to zinc ion GO:0010043 12 8 0,000 4,717E-03 0,01748742 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 4,717E-03 0,01746093 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 4,717E-03 0,01743451 ! oligopeptide transport GO:0006857 16 8 0,000 4,717E-03 0,01740817 ! actin-myosin filament sliding GO:0033275 13 8 0,000 4,717E-03 0,01738192 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 4,717E-03 0,01735574 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 4,717E-03 0,01732964 ! signal peptide processing GO:0006465 12 8 0,000 4,717E-03 0,01730362 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 4,717E-03 0,01727768 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 4,717E-03 0,01725181 ! macrophage chemotaxis GO:0048246 12 8 0,000 4,717E-03 0,01722603 ! succinate metabolic process GO:0006105 17 8 0,000 4,717E-03 0,01720031 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 4,717E-03 0,01717468 ! membrane hyperpolarization GO:0060081 11 8 0,000 4,717E-03 0,01714912 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 4,717E-03 0,01712364 ! estrogen metabolic process GO:0008210 17 8 0,000 4,717E-03 0,01709824 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 4,717E-03 0,01707291 ! T-helper 1 type immune response GO:0042088 12 8 0,000 4,717E-03 0,01704765 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 4,717E-03 0,01702247 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 4,717E-03 0,01699736 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 4,717E-03 0,01697233 ! reflex GO:0060004 17 8 0,000 4,717E-03 0,01694737 ! endothelial cell differentiation GO:0045446 17 8 0,000 4,717E-03 0,01692248 ! glycerolipid catabolic process GO:0046503 14 8 0,000 4,717E-03 0,01689767 ! hemoglobin metabolic process GO:0020027 14 8 0,000 4,717E-03 0,01687293 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 4,717E-03 0,01684826 ! pigment granule organization GO:0048753 17 8 0,000 4,717E-03 0,01682367 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 4,717E-03 0,01679914 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 4,717E-03 0,01677469 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 4,717E-03 0,01675031 ! astrocyte differentiation GO:0048708 19 8 0,000 4,717E-03 0,016726 ! histidine catabolic process GO:0006548 10 8 0,000 4,717E-03 0,01670176 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 4,717E-03 0,01667758 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 4,717E-03 0,01665348 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 4,717E-03 0,01662945 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 4,717E-03 0,01660549 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 4,717E-03 0,0165816 ! regulation of pigmentation during development GO:0048070 25 8 0,000 4,717E-03 0,01655777 ! melanin metabolic process GO:0006582 17 8 0,000 4,717E-03 0,01653402 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 4,717E-03 0,01651033 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 4,717E-03 0,01648671 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 4,717E-03 0,01646316 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 4,717E-03 0,01643967 ! macrophage activation GO:0042116 13 8 0,000 4,717E-03 0,01641625 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 4,717E-03 0,0163929 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 4,717E-03 0,01636962 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 4,717E-03 0,0163464 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 4,717E-03 0,01632325 ! purine salvage GO:0043101 12 8 0,000 4,717E-03 0,01630016 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 4,717E-03 0,01627713 ! regulation of vascular permeability GO:0043114 12 8 0,000 4,717E-03 0,01625418 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 4,717E-03 0,01623128 ! osteoblast development GO:0002076 17 8 0,000 4,717E-03 0,01620845 ! positive regulation of vasodilation GO:0045909 14 8 0,000 4,717E-03 0,01618569 ! negative regulation of translational initiation GO:0045947 12 8 0,000 4,717E-03 0,01616299 ! Schwann cell differentiation GO:0014037 21 8 0,000 4,717E-03 0,01614035 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 4,717E-03 0,01611778 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 4,717E-03 0,01609527 ! response to UV-B GO:0010224 17 8 0,000 4,717E-03 0,01607282 ! protein targeting to vacuole GO:0006623 14 8 0,000 4,717E-03 0,01605043 ! protein retention in ER lumen GO:0006621 14 8 0,000 4,717E-03 0,01602811 ! intermediate filament organization GO:0045109 12 8 0,000 4,717E-03 0,01600585 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 4,717E-03 0,01598365 ! cellular extravasation GO:0045123 13 8 0,000 4,717E-03 0,01596151 ! cardiac muscle cell development GO:0055013 14 8 0,000 4,717E-03 0,01593943 ! response to antibiotic GO:0046677 11 8 0,000 4,717E-03 0,01591742 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 4,717E-03 0,01589546 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 4,717E-03 0,01587357 ! DNA topological change GO:0006265 12 8 0,000 4,717E-03 0,01585173 ! response to tropane GO:0014073 15 8 0,000 4,717E-03 0,01582996 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 4,717E-03 0,01580825 ! melanosome transport GO:0032402 13 8 0,000 4,717E-03 0,01578659 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 0,000 4,717E-03 0,01576499 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 4,717E-03 0,01574346 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 4,717E-03 0,01572198 ! mast cell activation GO:0045576 14 8 0,000 4,717E-03 0,01570056 ! multicellular organismal aging GO:0010259 20 8 0,000 4,717E-03 0,0156792 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 4,717E-03 0,0156579 ! gas homeostasis GO:0033483 14 8 0,000 4,717E-03 0,01563665 ! dendrite morphogenesis GO:0048813 14 8 0,000 4,717E-03 0,01561546 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 4,717E-03 0,01559433 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 4,717E-03 0,01557326 ! nucleosome disassembly GO:0006337 14 8 0,000 4,717E-03 0,01555224 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 4,717E-03 0,01553128 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 4,717E-03 0,01551038 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 4,717E-03 0,01548953 ! establishment of chromosome localization GO:0051303 14 8 0,000 4,717E-03 0,01546874 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 4,717E-03 0,015448 ! intracellular lipid transport GO:0032365 16 8 0,000 4,717E-03 0,01542732 ! response to tumor cell GO:0002347 16 8 0,000 4,717E-03 0,0154067 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 4,717E-03 0,01538613 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 4,717E-03 0,01536561 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 4,717E-03 0,01534515 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 4,717E-03 0,01532475 ! positive regulation of epidermis development GO:0045684 13 8 0,000 4,717E-03 0,0153044 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 4,717E-03 0,0152841 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 4,717E-03 0,01526386 ! hormone catabolic process GO:0042447 17 8 0,000 4,717E-03 0,01524367 ! glycolipid catabolic process GO:0019377 16 8 0,000 4,717E-03 0,01522353 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 4,717E-03 0,01520344 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 4,717E-03 0,01518341 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 4,717E-03 0,01516344 ! positive regulation of glucose import GO:0046326 8 8 0,000 4,717E-03 0,01514351 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 4,717E-03 0,01512364 ! adult feeding behavior GO:0008343 10 8 0,000 4,717E-03 0,01510382 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 4,717E-03 0,01508405 ! ATP catabolic process GO:0006200 11 8 0,000 4,717E-03 0,01506433 ! blastocyst growth GO:0001832 19 8 0,000 4,717E-03 0,01504466 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 4,717E-03 0,01502505 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 4,717E-03 0,01500548 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 4,717E-03 0,01498597 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 4,717E-03 0,01496651 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 4,717E-03 0,0149471 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 4,717E-03 0,01492773 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 4,717E-03 0,01490842 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 4,717E-03 0,01488916 ! amino sugar catabolic process GO:0046348 11 8 0,000 4,717E-03 0,01486995 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 4,717E-03 0,01485079 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 4,717E-03 0,01483167 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 4,717E-03 0,01481261 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 4,717E-03 0,0147936 ! behavioral response to nicotine GO:0035095 12 8 0,000 4,717E-03 0,01477463 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 4,717E-03 0,01475571 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 4,717E-03 0,01473684 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 4,717E-03 0,01471802 ! NAD biosynthetic process GO:0009435 17 8 0,000 4,717E-03 0,01469925 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 4,717E-03 0,01468052 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 4,717E-03 0,01466185 ! axon extension GO:0048675 16 9 0,000 5,305E-03 0,01646899 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 5,305E-03 0,01644809 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 5,305E-03 0,01642724 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 5,305E-03 0,01640645 ! pentose-phosphate shunt GO:0006098 16 9 0,000 5,305E-03 0,0163857 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 5,305E-03 0,01636501 ! cell proliferation in forebrain GO:0021846 18 9 0,000 5,305E-03 0,01634438 ! neutral lipid catabolic process GO:0046461 14 9 0,000 5,305E-03 0,01632379 ! reproductive behavior GO:0019098 22 9 0,000 5,305E-03 0,01630326 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 5,305E-03 0,01628278 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 5,305E-03 0,01626235 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 5,305E-03 0,01624197 ! UTP metabolic process GO:0046051 10 9 0,000 5,305E-03 0,01622164 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 5,305E-03 0,01620136 ! induction of positive chemotaxis GO:0050930 17 9 0,000 5,305E-03 0,01618114 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 5,305E-03 0,01616096 ! artery development GO:0060840 25 9 0,000 5,305E-03 0,01614084 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 5,305E-03 0,01612076 ! regulation of glycolysis GO:0006110 20 9 0,000 5,305E-03 0,01610074 ! cerebral cortex cell migration GO:0021795 18 9 0,000 5,305E-03 0,01608076 ! equilibrioception GO:0050957 20 9 0,000 5,305E-03 0,01606083 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 5,305E-03 0,01604096 ! chemosensory behavior GO:0007635 21 9 0,000 5,305E-03 0,01602113 ! microtubule bundle formation GO:0001578 22 9 0,000 5,305E-03 0,01600135 ! middle ear morphogenesis GO:0042474 14 9 0,000 5,305E-03 0,01598162 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 5,305E-03 0,01596194 ! leukocyte degranulation GO:0043299 16 9 0,000 5,305E-03 0,0159423 ! ganglioside metabolic process GO:0001573 22 9 0,000 5,305E-03 0,01592272 ! negative regulation of endocytosis GO:0045806 12 9 0,000 5,305E-03 0,01590318 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 5,305E-03 0,01588369 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 5,305E-03 0,01586425 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 5,305E-03 0,01584486 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 5,305E-03 0,01582551 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 5,305E-03 0,01580621 ! protein targeting to ER GO:0045047 25 9 0,000 5,305E-03 0,01578696 ! ceramide biosynthetic process GO:0046513 20 9 0,000 5,305E-03 0,01576775 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 5,305E-03 0,01574859 ! T cell selection GO:0045058 27 9 0,000 5,305E-03 0,01572948 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 0,000 5,305E-03 0,01571041 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 5,305E-03 0,01569139 ! glycine catabolic process GO:0006546 15 9 0,000 5,305E-03 0,01567242 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 5,305E-03 0,01565349 ! endosome organization GO:0007032 20 9 0,000 5,305E-03 0,01563461 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 5,305E-03 0,01561577 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 5,305E-03 0,01559698 ! regulation of type I interferon production GO:0032479 12 9 0,000 5,305E-03 0,01557824 ! mannose metabolic process GO:0006013 13 9 0,000 5,305E-03 0,01555953 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 5,305E-03 0,01554088 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 5,305E-03 0,01552227 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 5,305E-03 0,0155037 ! Rac protein signal transduction GO:0016601 20 9 0,000 5,305E-03 0,01548518 ! receptor clustering GO:0043113 20 9 0,000 5,305E-03 0,0154667 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 5,305E-03 0,01544826 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 5,305E-03 0,01542987 ! retinol metabolic process GO:0042572 20 9 0,000 5,305E-03 0,01541152 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 5,305E-03 0,01539322 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 5,305E-03 0,01537496 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 5,305E-03 0,01535674 ! macrophage differentiation GO:0030225 15 9 0,000 5,305E-03 0,01533857 ! oligodendrocyte development GO:0014003 11 9 0,000 5,305E-03 0,01532044 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 5,305E-03 0,01530235 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 5,305E-03 0,01528431 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 5,305E-03 0,0152663 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 5,305E-03 0,01524834 ! response to amine stimulus GO:0014075 13 9 0,000 5,305E-03 0,01523043 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 5,305E-03 0,01521255 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 5,305E-03 0,01519471 ! erythrocyte development GO:0048821 17 9 0,000 5,305E-03 0,01517692 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 5,305E-03 0,01515917 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 5,305E-03 0,01514146 ! renal water homeostasis GO:0003091 15 9 0,000 5,305E-03 0,01512379 ! postreplication repair GO:0006301 25 9 0,000 5,305E-03 0,01510617 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 5,305E-03 0,01508858 ! icosanoid secretion GO:0032309 15 9 0,000 5,305E-03 0,01507104 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 5,305E-03 0,01505353 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 5,305E-03 0,01503607 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 5,305E-03 0,01501865 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 5,305E-03 0,01500126 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 5,305E-03 0,01498392 ! sterol catabolic process GO:0016127 14 9 0,000 5,305E-03 0,01496662 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 5,305E-03 0,01494936 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 5,305E-03 0,01493213 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 5,305E-03 0,01491495 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 5,305E-03 0,01489781 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 5,305E-03 0,0148807 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 5,305E-03 0,01486364 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 5,305E-03 0,01484661 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 5,305E-03 0,01482962 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 5,305E-03 0,01481268 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 5,305E-03 0,01479577 ! regulation of synaptogenesis GO:0051963 15 9 0,000 5,305E-03 0,0147789 ! purine base metabolic process GO:0006144 25 9 0,000 5,305E-03 0,01476206 ! pigment granule transport GO:0051904 17 9 0,000 5,305E-03 0,01474527 ! regulation of telomere maintenance GO:0032204 17 9 0,000 5,305E-03 0,01472851 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 5,305E-03 0,0147118 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 5,305E-03 0,01469512 ! regulation of muscle adaptation GO:0043502 14 9 0,000 5,305E-03 0,01467847 ! regulation of amino acid transport GO:0051955 12 9 0,000 5,305E-03 0,01466187 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 5,305E-03 0,0146453 ! mitochondrion localization GO:0051646 18 9 0,000 5,305E-03 0,01462877 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 5,893E-03 0,0162313 ! regulation of developmental growth GO:0048638 16 10 0,000 5,893E-03 0,01621302 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 0,000 5,893E-03 0,01619478 ! autophagic vacuole formation GO:0000045 17 10 0,000 5,893E-03 0,01617659 ! negative regulation of blood pressure GO:0045776 26 10 0,000 5,893E-03 0,01615843 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 5,893E-03 0,01614032 ! associative learning GO:0008306 21 10 0,000 5,893E-03 0,01612224 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 5,893E-03 0,01610421 ! regulation of phosphatase activity GO:0010921 28 10 0,000 5,893E-03 0,01608622 ! phosphate transport GO:0006817 24 10 0,000 5,893E-03 0,01606826 ! cell volume homeostasis GO:0006884 17 10 0,000 5,893E-03 0,01605035 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 5,893E-03 0,01603248 ! CTP metabolic process GO:0046036 11 10 0,000 5,893E-03 0,01601464 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 5,893E-03 0,01599685 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 5,893E-03 0,01597909 ! GTP metabolic process GO:0046039 11 10 0,000 5,893E-03 0,01596138 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 5,893E-03 0,0159437 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 5,893E-03 0,01592607 ! social behavior GO:0035176 29 10 0,000 5,893E-03 0,01590847 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 5,893E-03 0,01589091 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 5,893E-03 0,01587339 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 5,893E-03 0,01585591 ! androgen metabolic process GO:0008209 17 10 0,000 5,893E-03 0,01583846 ! phospholipid efflux GO:0033700 19 10 0,000 5,893E-03 0,01582106 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 5,893E-03 0,01580369 ! bile acid and bile salt transport GO:0015721 15 10 0,000 5,893E-03 0,01578636 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 5,893E-03 0,01576907 ! positive regulation of heart contraction GO:0045823 17 10 0,000 5,893E-03 0,01575182 ! lung alveolus development GO:0048286 26 10 0,000 5,893E-03 0,01573461 ! pathogenesis GO:0009405 17 10 0,000 5,893E-03 0,01571743 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 5,893E-03 0,01570029 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 5,893E-03 0,01568318 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 5,893E-03 0,01566612 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 5,893E-03 0,01564909 ! endoderm development GO:0007492 18 10 0,000 5,893E-03 0,0156321 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 5,893E-03 0,01561514 ! arginine catabolic process GO:0006527 17 10 0,000 5,893E-03 0,01559823 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 5,893E-03 0,01558135 ! proline metabolic process GO:0006560 13 10 0,000 5,893E-03 0,0155645 ! glucan biosynthetic process GO:0009250 14 10 0,000 5,893E-03 0,01554769 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 5,893E-03 0,01553092 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 5,893E-03 0,01551418 ! V(D)J recombination GO:0033151 34 10 0,000 5,893E-03 0,01549749 ! reverse cholesterol transport GO:0043691 19 10 0,000 5,893E-03 0,01548082 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 5,893E-03 0,01546419 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 5,893E-03 0,0154476 ! B cell proliferation GO:0042100 19 10 0,000 5,893E-03 0,01543104 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 5,893E-03 0,01541452 ! regulation of sodium ion transport GO:0002028 26 10 0,000 5,893E-03 0,01539804 ! multicellular organism growth GO:0035264 19 10 0,000 5,893E-03 0,01538159 ! phagocytosis, engulfment GO:0006911 33 10 0,000 5,893E-03 0,01536517 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 5,893E-03 0,01534879 ! ruffle organization GO:0031529 17 10 0,000 5,893E-03 0,01533244 ! epithelial cell development GO:0002064 21 10 0,000 5,893E-03 0,01531613 ! lens development in camera-type eye GO:0002088 17 10 0,000 5,893E-03 0,01529986 ! retinoic acid metabolic process GO:0042573 14 10 0,000 5,893E-03 0,01528361 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 5,893E-03 0,01526741 ! positive regulation of translational initiation GO:0045948 12 10 0,000 5,893E-03 0,01525123 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 5,893E-03 0,01523509 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 5,893E-03 0,01521899 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 5,893E-03 0,01520292 ! motor axon guidance GO:0008045 22 10 0,000 5,893E-03 0,01518688 ! copper ion homeostasis GO:0055070 13 10 0,000 5,893E-03 0,01517088 ! regulation of bone resorption GO:0045124 25 10 0,000 5,893E-03 0,01515491 ! protein heterooligomerization GO:0051291 17 10 0,000 5,893E-03 0,01513897 ! regulation of gliogenesis GO:0014013 23 10 0,000 5,893E-03 0,01512307 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 5,893E-03 0,0151072 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 5,893E-03 0,01509137 ! segment specification GO:0007379 15 10 0,000 5,893E-03 0,01507556 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 5,893E-03 0,01505979 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 5,893E-03 0,01504406 ! blastoderm segmentation GO:0007350 19 10 0,000 5,893E-03 0,01502835 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 5,893E-03 0,01501268 ! response to dsRNA GO:0043331 23 10 0,000 5,893E-03 0,01499705 ! DNA ligation GO:0006266 18 10 0,000 5,893E-03 0,01498144 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 5,893E-03 0,01496587 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 5,893E-03 0,01495033 ! melanosome localization GO:0032400 16 10 0,000 5,893E-03 0,01493482 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 5,893E-03 0,01491934 ! regulation of B cell differentiation GO:0045577 24 10 0,000 5,893E-03 0,0149039 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 5,893E-03 0,01488848 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 5,893E-03 0,0148731 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 5,893E-03 0,01485775 ! induction of an organ GO:0001759 17 10 0,000 5,893E-03 0,01484244 ! leukocyte activation during immune response GO:0002366 15 10 0,000 5,893E-03 0,01482715 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 5,893E-03 0,0148119 ! protein sumoylation GO:0016925 17 10 0,000 5,893E-03 0,01479667 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 5,893E-03 0,01478148 ! hindbrain morphogenesis GO:0021575 19 10 0,000 5,893E-03 0,01476632 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 5,893E-03 0,01475119 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 5,893E-03 0,01473609 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 5,893E-03 0,01472103 ! salivary gland development GO:0007431 28 10 0,000 5,893E-03 0,01470599 ! ubiquinone metabolic process GO:0006743 17 10 0,000 5,893E-03 0,01469098 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 5,893E-03 0,01467601 ! midbrain development GO:0030901 14 10 0,000 5,893E-03 0,01466106 ! musculoskeletal movement GO:0050881 16 10 0,000 5,893E-03 0,01464615 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 5,893E-03 0,01463126 ! methionine biosynthetic process GO:0009086 21 10 0,000 5,893E-03 0,01461641 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 5,893E-03 0,01460159 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 5,893E-03 0,01458679 ! quaternary ammonium group transport GO:0015697 22 10 0,000 5,893E-03 0,01457203 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 5,893E-03 0,01455729 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 5,893E-03 0,01454259 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 5,893E-03 0,01452791 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 5,893E-03 0,01451327 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 5,893E-03 0,01449865 ! establishment of pigment granule localization GO:0051905 18 10 0,000 5,893E-03 0,01448407 ! blastocyst formation GO:0001825 18 10 0,000 5,893E-03 0,01446951 ! regulation of fibrinolysis GO:0051917 20 10 0,000 5,893E-03 0,01445498 ! cerebellar cortex development GO:0021695 16 10 0,000 5,893E-03 0,01444049 ! positive regulation of amine transport GO:0051954 17 10 0,000 5,893E-03 0,01442602 ! response to nicotine GO:0035094 20 10 0,000 5,893E-03 0,01441158 ! negative regulation of immune effector process GO:0002698 23 10 0,000 5,893E-03 0,01439716 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 5,893E-03 0,01438278 ! negative regulation of muscle development GO:0048635 27 11 0,000 6,481E-03 0,01580083 ! respiratory burst GO:0045730 17 11 0,000 6,481E-03 0,01578507 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 6,481E-03 0,01576935 ! neuron fate specification GO:0048665 18 11 0,000 6,481E-03 0,01575366 ! telencephalon cell migration GO:0022029 23 11 0,000 6,481E-03 0,015738 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 6,481E-03 0,01572237 ! thyroid gland development GO:0030878 26 11 0,000 6,481E-03 0,01570677 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 6,481E-03 0,01569121 ! synapsis GO:0007129 14 11 0,000 6,481E-03 0,01567567 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 6,481E-03 0,01566017 ! Golgi vesicle budding GO:0048194 26 11 0,000 6,481E-03 0,01564469 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 6,481E-03 0,01562925 ! response to pain GO:0048265 27 11 0,000 6,481E-03 0,01561383 ! detection of mechanical stimulus GO:0050982 22 11 0,000 6,481E-03 0,01559845 ! keratinocyte proliferation GO:0043616 19 11 0,000 6,481E-03 0,0155831 ! blood vessel remodeling GO:0001974 30 11 0,000 6,481E-03 0,01556778 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 6,481E-03 0,01555248 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 6,481E-03 0,01553722 ! bone resorption GO:0045453 16 11 0,000 6,481E-03 0,01552199 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 6,481E-03 0,01550678 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 6,481E-03 0,01549161 ! negative regulation of proteolysis GO:0045861 25 11 0,000 6,481E-03 0,01547647 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 6,481E-03 0,01546135 ! melanocyte differentiation GO:0030318 20 11 0,000 6,481E-03 0,01544627 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 6,481E-03 0,01543122 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 6,481E-03 0,01541619 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 6,481E-03 0,01540119 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 6,481E-03 0,01538623 ! regulation of intracellular pH GO:0051453 21 11 0,000 6,481E-03 0,01537129 ! substrate-bound cell migration GO:0006929 14 11 0,000 6,481E-03 0,01535638 ! UV protection GO:0009650 20 11 0,000 6,481E-03 0,0153415 ! adult heart development GO:0007512 16 11 0,000 6,481E-03 0,01532665 ! chondrocyte differentiation GO:0002062 27 11 0,000 6,481E-03 0,01531183 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 6,481E-03 0,01529703 ! macroautophagy GO:0016236 19 11 0,000 6,481E-03 0,01528227 ! temperature homeostasis GO:0001659 18 11 0,000 6,481E-03 0,01526753 ! behavioral fear response GO:0001662 27 11 0,000 6,481E-03 0,01525282 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 6,481E-03 0,01523814 ! negative regulation of ossification GO:0030279 27 11 0,000 6,481E-03 0,01522349 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 6,481E-03 0,01520886 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 6,481E-03 0,01519427 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 6,481E-03 0,0151797 ! alpha-beta T cell activation GO:0046631 26 11 0,000 6,481E-03 0,01516516 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 6,481E-03 0,01515065 ! regulation of organ growth GO:0046620 14 11 0,000 6,481E-03 0,01513616 ! pigment granule localization GO:0051875 20 11 0,000 6,481E-03 0,01512171 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 6,481E-03 0,01510728 ! vasoconstriction GO:0042310 20 11 0,000 6,481E-03 0,01509288 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 6,481E-03 0,0150785 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 6,481E-03 0,01506416 ! embryonic axis specification GO:0000578 19 11 0,000 6,481E-03 0,01504984 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 6,481E-03 0,01503554 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 6,481E-03 0,01502128 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 6,481E-03 0,01500704 ! nitric oxide metabolic process GO:0046209 17 11 0,000 6,481E-03 0,01499283 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 6,481E-03 0,01497864 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 6,481E-03 0,01496449 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 6,481E-03 0,01495036 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 6,481E-03 0,01493625 ! prophase GO:0051324 17 11 0,000 6,481E-03 0,01492217 ! neuroblast proliferation GO:0007405 25 11 0,000 6,481E-03 0,01490812 ! nucleosome positioning GO:0016584 15 11 0,000 6,481E-03 0,0148941 ! regulation of isotype switching GO:0045191 24 11 0,000 6,481E-03 0,0148801 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 6,481E-03 0,01486613 ! negative regulation of neurological system process GO:0031645 21 11 0,000 6,481E-03 0,01485218 ! apical protein localization GO:0045176 18 11 0,000 6,481E-03 0,01483826 ! acid secretion GO:0046717 20 11 0,000 6,481E-03 0,01482437 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 6,481E-03 0,0148105 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 6,481E-03 0,01479666 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 6,481E-03 0,01478285 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 6,481E-03 0,01476906 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 6,481E-03 0,01475529 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 6,481E-03 0,01474155 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 6,481E-03 0,01472784 ! cholesterol efflux GO:0033344 21 11 0,000 6,481E-03 0,01471415 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 6,481E-03 0,01470049 ! oocyte development GO:0048599 20 11 0,000 6,481E-03 0,01468685 ! negative regulation of glucose import GO:0046325 18 11 0,000 6,481E-03 0,01467324 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 6,481E-03 0,01465965 ! embryonic gut development GO:0048566 19 11 0,000 6,481E-03 0,01464609 ! regulation of organic acid transport GO:0032890 19 11 0,000 6,481E-03 0,01463256 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 6,481E-03 0,01461905 ! activation of innate immune response GO:0002218 16 11 0,000 6,481E-03 0,01460556 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 6,481E-03 0,0145921 ! cardiac cell differentiation GO:0035051 36 11 0,000 6,481E-03 0,01457866 ! lysogeny GO:0030069 22 11 0,000 6,481E-03 0,01456525 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 6,481E-03 0,01455186 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 6,481E-03 0,0145385 ! sequestering of metal ion GO:0051238 15 11 0,000 6,481E-03 0,01452516 ! regulation of embryonic development GO:0045995 35 11 0,000 6,481E-03 0,01451185 ! nucleus localization GO:0051647 22 11 0,000 6,481E-03 0,01449856 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 7,068E-03 0,0157977 ! positive regulation of blood pressure GO:0045777 18 12 0,000 7,068E-03 0,01578326 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 7,068E-03 0,01576884 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 7,068E-03 0,01575446 ! virus-host interaction GO:0019048 30 12 0,000 7,068E-03 0,01574009 ! regulation of B cell proliferation GO:0030888 22 12 0,000 7,068E-03 0,01572576 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 7,068E-03 0,01571145 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 7,068E-03 0,01569717 ! protein complex disassembly GO:0043241 28 12 0,000 7,068E-03 0,01568291 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 7,068E-03 0,01566868 ! regulation of cell projection assembly GO:0060491 33 12 0,000 7,068E-03 0,01565447 ! hippocampus development GO:0021766 29 12 0,000 7,068E-03 0,01564029 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 7,068E-03 0,01562614 ! cytokine biosynthetic process GO:0042089 23 12 0,000 7,068E-03 0,01561201 ! T cell proliferation GO:0042098 32 12 0,000 7,068E-03 0,01559791 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 7,068E-03 0,01558383 ! regulation of exit from mitosis GO:0007096 19 12 0,000 7,068E-03 0,01556978 ! ventral spinal cord development GO:0021517 25 12 0,000 7,068E-03 0,01555575 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 7,068E-03 0,01554175 ! drug transport GO:0015893 16 12 0,000 7,068E-03 0,01552777 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 7,068E-03 0,01551382 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 7,068E-03 0,0154999 ! tyrosine metabolic process GO:0006570 19 12 0,000 7,068E-03 0,01548599 ! polyamine metabolic process GO:0006595 18 12 0,000 7,068E-03 0,01547212 ! focal adhesion formation GO:0048041 37 12 0,000 7,068E-03 0,01545827 ! mitotic spindle organization GO:0007052 23 12 0,000 7,068E-03 0,01544444 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 7,068E-03 0,01543064 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 7,068E-03 0,01541686 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 7,068E-03 0,01540311 ! lipid digestion GO:0044241 21 12 0,000 7,068E-03 0,01538938 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 7,068E-03 0,01537568 ! entry into host cell GO:0030260 34 12 0,000 7,068E-03 0,015362 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 7,068E-03 0,01534834 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 7,068E-03 0,01533471 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 7,068E-03 0,0153211 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 7,068E-03 0,01530752 ! protein targeting to peroxisome GO:0006625 27 12 0,000 7,068E-03 0,01529396 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 7,068E-03 0,01528043 ! regulation of phagocytosis GO:0050764 17 12 0,000 7,068E-03 0,01526692 ! snRNA metabolic process GO:0016073 30 12 0,000 7,068E-03 0,01525343 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 7,068E-03 0,01523997 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 7,068E-03 0,01522653 ! cranial nerve development GO:0021545 23 12 0,000 7,068E-03 0,01521311 ! fucose catabolic process GO:0019317 25 12 0,000 7,068E-03 0,01519972 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 7,068E-03 0,01518635 ! histone acetylation GO:0016573 27 12 0,000 7,068E-03 0,01517301 ! mRNA polyadenylation GO:0006378 24 12 0,000 7,068E-03 0,01515969 ! autonomic nervous system development GO:0048483 24 12 0,000 7,068E-03 0,01514639 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 7,068E-03 0,01513311 ! zymogen activation GO:0031638 18 12 0,000 7,068E-03 0,01511986 ! peptidyl-lysine modification GO:0018205 21 12 0,000 7,068E-03 0,01510663 ! T cell homeostasis GO:0043029 28 12 0,000 7,068E-03 0,01509343 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 7,068E-03 0,01508025 ! glutathione biosynthetic process GO:0006750 15 12 0,000 7,068E-03 0,01506709 ! regulation of leukocyte migration GO:0002685 29 12 0,000 7,068E-03 0,01505395 ! oocyte differentiation GO:0009994 21 12 0,000 7,068E-03 0,01504084 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 7,068E-03 0,01502775 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 7,068E-03 0,01501468 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 7,068E-03 0,01500164 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 7,068E-03 0,01498861 ! defense response to fungus GO:0050832 15 12 0,000 7,068E-03 0,01497561 ! developmental induction GO:0031128 22 12 0,000 7,068E-03 0,01496264 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 7,068E-03 0,01494968 ! lamellipodium assembly GO:0030032 24 12 0,000 7,068E-03 0,01493675 ! response to cold GO:0009409 17 12 0,000 7,068E-03 0,01492384 ! establishment of cell polarity GO:0030010 21 12 0,000 7,068E-03 0,01491095 ! regulation of synapse organization GO:0050807 18 12 0,000 7,068E-03 0,01489809 ! localization within membrane GO:0051668 26 12 0,000 7,068E-03 0,01488524 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 7,655E-03 0,01610726 ! cGMP metabolic process GO:0046068 18 13 0,000 7,655E-03 0,0160934 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 7,655E-03 0,01607956 ! regulation of chemokine production GO:0032642 18 13 0,000 7,655E-03 0,01606575 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 7,655E-03 0,01605196 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 7,655E-03 0,01603819 ! peroxisomal transport GO:0043574 28 13 0,000 7,655E-03 0,01602445 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 7,655E-03 0,01601073 ! cartilage condensation GO:0001502 22 13 0,000 7,655E-03 0,01599703 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 7,655E-03 0,01598336 ! organelle fusion GO:0048284 36 13 0,000 7,655E-03 0,01596971 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 7,655E-03 0,01595608 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 7,655E-03 0,01594248 ! pseudouridine synthesis GO:0001522 19 13 0,000 7,655E-03 0,0159289 ! endocrine pancreas development GO:0031018 25 13 0,000 7,655E-03 0,01591535 ! positive regulation of cell growth GO:0030307 24 13 0,000 7,655E-03 0,01590181 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 7,655E-03 0,0158883 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 7,655E-03 0,01587481 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 7,655E-03 0,01586135 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 7,655E-03 0,01584791 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 7,655E-03 0,01583449 ! methionine metabolic process GO:0006555 31 13 0,000 7,655E-03 0,01582109 ! plasma membrane organization GO:0007009 27 13 0,000 7,655E-03 0,01580772 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 7,655E-03 0,01579437 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 7,655E-03 0,01578104 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 7,655E-03 0,01576773 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 7,655E-03 0,01575445 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 7,655E-03 0,01574119 ! cytokine metabolic process GO:0042107 24 13 0,000 7,655E-03 0,01572795 ! exocrine system development GO:0035272 34 13 0,000 7,655E-03 0,01571473 ! asymmetric protein localization GO:0008105 24 13 0,000 7,655E-03 0,01570154 ! membrane protein proteolysis GO:0033619 33 13 0,000 7,655E-03 0,01568837 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 7,655E-03 0,01567522 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 7,655E-03 0,01566209 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 7,655E-03 0,01564898 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 7,655E-03 0,0156359 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 7,655E-03 0,01562283 ! protein homotetramerization GO:0051289 24 13 0,000 7,655E-03 0,01560979 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 7,655E-03 0,01559677 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 7,655E-03 0,01558378 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 7,655E-03 0,0155708 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 7,655E-03 0,01555785 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 7,655E-03 0,01554491 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 7,655E-03 0,015532 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 7,655E-03 0,01551911 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 7,655E-03 0,01550625 ! histone methylation GO:0016571 29 13 0,000 7,655E-03 0,0154934 ! chromatin silencing GO:0006342 29 13 0,000 7,655E-03 0,01548057 ! gland morphogenesis GO:0022612 31 13 0,000 7,655E-03 0,01546777 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 7,655E-03 0,01545498 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 7,655E-03 0,01544222 ! regulation of epidermis development GO:0045682 19 13 0,000 7,655E-03 0,01542948 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 7,655E-03 0,01541676 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 7,655E-03 0,01540406 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 7,655E-03 0,01539138 ! spleen development GO:0048536 24 13 0,000 7,655E-03 0,01537873 ! regulation of mRNA stability GO:0043488 32 13 0,000 7,655E-03 0,01536609 ! digestive tract morphogenesis GO:0048546 31 13 0,000 7,655E-03 0,01535347 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 7,655E-03 0,01534088 ! anterior/posterior axis specification GO:0009948 22 13 0,000 7,655E-03 0,0153283 ! regulation of RNA splicing GO:0043484 22 13 0,000 7,655E-03 0,01531575 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 7,655E-03 0,01530322 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 7,655E-03 0,0152907 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 7,655E-03 0,01527821 ! mRNA 3'-end processing GO:0031124 25 13 0,000 7,655E-03 0,01526574 ! insulin secretion GO:0030073 24 13 0,000 7,655E-03 0,01525329 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 7,655E-03 0,01524086 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 7,655E-03 0,01522845 ! acrosome reaction GO:0007340 19 13 0,000 7,655E-03 0,01521605 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 7,655E-03 0,01520368 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 7,655E-03 0,01519133 ! rRNA transcription GO:0009303 28 14 0,000 8,241E-03 0,01634202 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 8,241E-03 0,01632877 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 8,241E-03 0,01631554 ! water transport GO:0006833 21 14 0,000 8,241E-03 0,01630233 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 8,241E-03 0,01628914 ! non-recombinational repair GO:0000726 29 14 0,000 8,241E-03 0,01627597 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 8,241E-03 0,01626282 ! retina development in camera-type eye GO:0060041 28 14 0,000 8,241E-03 0,0162497 ! hair follicle morphogenesis GO:0031069 27 14 0,000 8,241E-03 0,01623659 ! RNA polyadenylation GO:0043631 32 14 0,000 8,241E-03 0,01622351 ! lipid localization GO:0010876 32 14 0,000 8,241E-03 0,01621045 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 8,241E-03 0,0161974 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 8,241E-03 0,01618438 ! regulated secretory pathway GO:0045055 24 14 0,000 8,241E-03 0,01617138 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 8,241E-03 0,01615841 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 8,241E-03 0,01614545 ! arginine metabolic process GO:0006525 21 14 0,000 8,241E-03 0,01613251 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 8,241E-03 0,01611959 ! cell-cell junction assembly GO:0007043 32 14 0,000 8,241E-03 0,0161067 ! regulation of heart rate GO:0002027 25 14 0,000 8,241E-03 0,01609382 ! fear response GO:0042596 34 14 0,000 8,241E-03 0,01608097 ! organic alcohol transport GO:0015850 29 14 0,000 8,241E-03 0,01606813 ! negative regulation of caspase activity GO:0043154 23 14 0,000 8,241E-03 0,01605532 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 8,241E-03 0,01604253 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 8,241E-03 0,01602976 ! neutral amino acid transport GO:0015804 28 14 0,000 8,241E-03 0,016017 ! bone mineralization GO:0030282 18 14 0,000 8,241E-03 0,01600427 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 8,241E-03 0,01599156 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 8,241E-03 0,01597887 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 8,241E-03 0,0159662 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 8,241E-03 0,01595354 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 8,241E-03 0,01594091 ! regulation of cellular pH GO:0030641 27 14 0,000 8,241E-03 0,0159283 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 8,241E-03 0,01591571 ! ribosome assembly GO:0042255 18 14 0,000 8,241E-03 0,01590314 ! cerebellum development GO:0021549 23 14 0,000 8,241E-03 0,01589059 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 8,241E-03 0,01587805 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 8,241E-03 0,01586554 ! negative regulation of protein secretion GO:0050709 30 14 0,000 8,241E-03 0,01585305 ! response to gamma radiation GO:0010332 30 14 0,000 8,241E-03 0,01584058 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 8,241E-03 0,01582812 ! NADP metabolic process GO:0006739 24 14 0,000 8,241E-03 0,01581569 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 8,241E-03 0,01580328 ! oxygen transport GO:0015671 22 14 0,000 8,241E-03 0,01579088 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 8,241E-03 0,01577851 ! male genitalia development GO:0030539 26 14 0,000 8,241E-03 0,01576615 ! regulation of RNA stability GO:0043487 33 14 0,000 8,241E-03 0,01575381 ! regulation of axon extension GO:0030516 43 14 0,000 8,241E-03 0,0157415 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 8,241E-03 0,0157292 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 8,241E-03 0,01571692 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 8,241E-03 0,01570466 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 8,827E-03 0,01680858 ! lactation GO:0007595 30 15 0,000 8,827E-03 0,01679549 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 8,827E-03 0,01678242 ! reproductive cellular process GO:0048610 22 15 0,000 8,827E-03 0,01676937 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 8,827E-03 0,01675634 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 8,827E-03 0,01674333 ! superoxide anion generation GO:0042554 22 15 0,000 8,827E-03 0,01673034 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 8,827E-03 0,01671737 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 8,827E-03 0,01670442 ! phospholipid catabolic process GO:0009395 27 15 0,000 8,827E-03 0,01669149 ! copper ion transport GO:0006825 22 15 0,000 8,827E-03 0,01667858 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 8,827E-03 0,01666569 ! cardiac muscle contraction GO:0060048 28 15 0,000 8,827E-03 0,01665282 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 8,827E-03 0,01663998 ! sulfate transport GO:0008272 27 15 0,000 8,827E-03 0,01662715 ! response to cAMP GO:0051591 25 15 0,000 8,827E-03 0,01661434 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 8,827E-03 0,01660155 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 8,827E-03 0,01658878 ! regulation of mRNA processing GO:0050684 26 15 0,000 8,827E-03 0,01657602 ! response to hexose stimulus GO:0009746 25 15 0,000 8,827E-03 0,01656329 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 8,827E-03 0,01655058 ! glycoprotein catabolic process GO:0006516 33 15 0,000 8,827E-03 0,01653789 ! vesicle coating GO:0006901 38 15 0,000 8,827E-03 0,01652522 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 8,827E-03 0,01651256 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 8,827E-03 0,01649993 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 8,827E-03 0,01648731 ! regulation of exocytosis GO:0017157 26 15 0,000 8,827E-03 0,01647472 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 8,827E-03 0,01646214 ! G1/S transition checkpoint GO:0031575 37 15 0,000 8,827E-03 0,01644959 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 8,827E-03 0,01643705 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 8,827E-03 0,01642453 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 8,827E-03 0,01641203 ! regulation of vasodilation GO:0042312 27 15 0,000 8,827E-03 0,01639955 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 8,827E-03 0,01638709 ! histone deacetylation GO:0016575 24 15 0,000 8,827E-03 0,01637465 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 8,827E-03 0,01636222 ! water homeostasis GO:0030104 28 15 0,000 8,827E-03 0,01634982 ! cofactor transport GO:0051181 30 15 0,000 8,827E-03 0,01633743 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 8,827E-03 0,01632506 ! muscle maintenance GO:0046716 26 15 0,000 8,827E-03 0,01631271 ! protein-chromophore linkage GO:0018298 25 15 0,000 8,827E-03 0,01630038 ! intestinal absorption GO:0050892 31 15 0,000 8,827E-03 0,01628807 ! dopamine metabolic process GO:0042417 35 15 0,000 8,827E-03 0,01627578 ! cAMP biosynthetic process GO:0006171 25 15 0,000 8,827E-03 0,01626351 ! heme biosynthetic process GO:0006783 33 15 0,000 8,827E-03 0,01625125 ! lymphocyte homeostasis GO:0002260 33 15 0,000 8,827E-03 0,01623901 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 8,827E-03 0,01622679 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 8,827E-03 0,01621459 ! L-fucose metabolic process GO:0042354 33 15 0,000 8,827E-03 0,01620241 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 8,827E-03 0,01619025 ! actin filament polymerization GO:0030041 27 15 0,000 8,827E-03 0,0161781 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 8,827E-03 0,01616597 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 9,413E-03 0,01722595 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 9,413E-03 0,01721305 ! positive regulation of cell size GO:0045793 29 16 0,000 9,413E-03 0,01720018 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 9,413E-03 0,01718732 ! dicarboxylic acid transport GO:0006835 47 16 0,000 9,413E-03 0,01717449 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 9,413E-03 0,01716167 ! bone remodeling GO:0046849 28 16 0,000 9,413E-03 0,01714887 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 9,413E-03 0,01713609 ! heterophilic cell adhesion GO:0007157 43 16 0,000 9,413E-03 0,01712333 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 9,413E-03 0,01711059 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 9,413E-03 0,01709787 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 9,413E-03 0,01708517 ! positive regulation of ion transport GO:0043270 23 16 0,000 9,413E-03 0,01707248 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 9,413E-03 0,01705982 ! startle response GO:0001964 28 16 0,000 9,413E-03 0,01704717 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 9,413E-03 0,01703455 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 9,413E-03 0,01702194 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 9,413E-03 0,01700935 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 9,413E-03 0,01699678 ! protein polyubiquitination GO:0000209 41 16 0,000 9,413E-03 0,01698422 ! glutamate metabolic process GO:0006536 25 16 0,000 9,413E-03 0,01697169 ! pituitary gland development GO:0021983 30 16 0,000 9,413E-03 0,01695917 ! response to osmotic stress GO:0006970 27 16 0,000 9,413E-03 0,01694667 ! lysosomal transport GO:0007041 31 16 0,000 9,413E-03 0,01693419 ! L-amino acid transport GO:0015807 33 16 0,000 9,413E-03 0,01692173 ! stem cell development GO:0048864 46 16 0,000 9,413E-03 0,01690929 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 9,413E-03 0,01689687 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 9,413E-03 0,01688446 ! intermediate filament-based process GO:0045103 36 16 0,000 9,413E-03 0,01687207 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 9,413E-03 0,0168597 ! negative regulation of immune response GO:0050777 38 16 0,000 9,413E-03 0,01684735 ! axon cargo transport GO:0008088 46 16 0,000 9,413E-03 0,01683502 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 9,413E-03 0,0168227 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 9,413E-03 0,01681041 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 9,413E-03 0,01679813 ! DNA replication initiation GO:0006270 28 16 0,000 9,413E-03 0,01678587 ! neuron recognition GO:0008038 40 16 0,000 9,413E-03 0,01677362 ! mRNA splice site selection GO:0006376 44 16 0,000 9,413E-03 0,0167614 ! tissue regeneration GO:0042246 27 16 0,000 9,413E-03 0,01674919 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 9,413E-03 0,016737 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 9,413E-03 0,01672483 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 9,413E-03 0,01671267 ! biomineral formation GO:0031214 22 16 0,000 9,413E-03 0,01670053 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 9,413E-03 0,01668842 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 9,413E-03 0,01667631 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 9,413E-03 0,01666423 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 9,413E-03 0,01665216 ! regulation of ATPase activity GO:0043462 26 16 0,000 9,413E-03 0,01664011 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 9,413E-03 0,01662808 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 9,413E-03 0,01661607 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 9,413E-03 0,01660407 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 9,413E-03 0,01659209 ! peptide hormone processing GO:0016486 27 16 0,000 9,413E-03 0,01658013 ! positive regulation of cell killing GO:0031343 36 17 0,000 9,999E-03 0,01759875 ! metencephalon development GO:0022037 32 17 0,000 9,999E-03 0,01758608 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 9,999E-03 0,01757342 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 9,999E-03 0,01756079 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 9,999E-03 0,01754818 ! signal complex assembly GO:0007172 47 17 0,000 9,999E-03 0,01753558 ! filopodium assembly GO:0046847 42 17 0,000 9,999E-03 0,017523 ! endothelial cell migration GO:0043542 31 17 0,000 9,999E-03 0,01751044 ! gene silencing by RNA GO:0031047 38 17 0,000 9,999E-03 0,01749789 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 9,999E-03 0,01748537 ! glial cell development GO:0021782 28 17 0,000 9,999E-03 0,01747286 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 9,999E-03 0,01746037 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 9,999E-03 0,0174479 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 9,999E-03 0,01743545 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 9,999E-03 0,01742301 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 9,999E-03 0,01741059 ! myoblast differentiation GO:0045445 50 17 0,000 9,999E-03 0,01739819 ! activation of MAPKK activity GO:0000186 43 17 0,000 9,999E-03 0,01738581 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 9,999E-03 0,01737344 ! regulation of survival gene product expression GO:0045884 38 17 0,000 9,999E-03 0,01736109 ! cardiac muscle tissue development GO:0048738 34 17 0,000 9,999E-03 0,01734876 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 9,999E-03 0,01733645 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 9,999E-03 0,01732416 ! complement activation, alternative pathway GO:0006957 19 17 0,000 9,999E-03 0,01731188 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 9,999E-03 0,01729962 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 9,999E-03 0,01728737 ! membrane budding GO:0006900 42 17 0,000 9,999E-03 0,01727515 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 9,999E-03 0,01726294 ! regulation of protein binding GO:0043393 33 17 0,000 9,999E-03 0,01725075 ! nucleobase metabolic process GO:0009112 43 17 0,000 9,999E-03 0,01723857 ! DNA unwinding during replication GO:0006268 26 17 0,000 9,999E-03 0,01722642 ! genitalia development GO:0048806 32 17 0,000 9,999E-03 0,01721428 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 9,999E-03 0,01720215 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 9,999E-03 0,01719005 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 9,999E-03 0,01717796 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 9,999E-03 0,01716589 ! neutrophil chemotaxis GO:0030593 29 17 0,000 9,999E-03 0,01715383 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 9,999E-03 0,0171418 ! steroid catabolic process GO:0006706 34 17 0,000 9,999E-03 0,01712978 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 9,999E-03 0,01711777 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 9,999E-03 0,01710578 ! gas transport GO:0015669 26 17 0,000 9,999E-03 0,01709381 ! organic cation transport GO:0015695 32 17 0,000 9,999E-03 0,01708186 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 9,999E-03 0,01706992 ! RNA 3'-end processing GO:0031123 37 17 0,000 9,999E-03 0,017058 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 9,999E-03 0,0170461 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,01058399 0,01803116 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,01058399 0,01801859 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,01058399 0,01800604 ! limbic system development GO:0021761 40 18 0,000 0,01058399 0,01799351 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,01058399 0,017981 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,01058399 0,0179685 ! adult walking behavior GO:0007628 36 18 0,000 0,01058399 0,01795603 ! patterning of blood vessels GO:0001569 43 18 0,000 0,01058399 0,01794357 ! heart looping GO:0001947 34 18 0,000 0,01058399 0,01793112 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,01058399 0,0179187 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,01058399 0,01790629 ! centrosome cycle GO:0007098 26 18 0,000 0,01058399 0,01789389 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,01058399 0,01788152 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,01058399 0,01786916 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,01058399 0,01785682 ! glycine metabolic process GO:0006544 30 18 0,000 0,01058399 0,0178445 ! glutamine metabolic process GO:0006541 29 18 0,000 0,01058399 0,01783219 ! response to retinoic acid GO:0032526 31 18 0,000 0,01058399 0,0178199 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,01058399 0,01780763 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 0,000 0,01058399 0,01779537 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,01058399 0,01778313 ! DNA integration GO:0015074 32 18 0,000 0,01058399 0,01777091 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,01058399 0,01775871 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,01058399 0,01774652 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,01058399 0,01773435 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,01058399 0,01772219 ! neural crest cell migration GO:0001755 41 18 0,000 0,01058399 0,01771005 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,01058399 0,01769793 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,01058399 0,01768583 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,01058399 0,01767374 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,01058399 0,01766166 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,01058399 0,01764961 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,01058399 0,01763757 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,01058399 0,01762555 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,01058399 0,01761354 ! detection of bacterium GO:0016045 22 18 0,000 0,01058399 0,01760155 ! nerve development GO:0021675 34 18 0,000 0,01058399 0,01758958 ! defense response to virus GO:0051607 43 18 0,000 0,01058399 0,01757762 ! microspike assembly GO:0030035 46 18 0,000 0,01058399 0,01756568 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,01058399 0,01755375 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,01058399 0,01754184 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,01116885 0,01849864 ! positive regulation of translation GO:0045727 31 19 0,000 0,01116885 0,0184861 ! negative regulation of defense response GO:0031348 27 19 0,000 0,01116885 0,01847359 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,01116885 0,01846109 ! neuron maturation GO:0042551 46 19 0,000 0,01116885 0,01844861 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,01116885 0,01843614 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,01116885 0,01842369 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,01116885 0,01841126 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,01116885 0,01839885 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,01116885 0,01838645 ! inositol metabolic process GO:0006020 33 19 0,000 0,01116885 0,01837407 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,01116885 0,0183617 ! memory GO:0007613 34 19 0,000 0,01116885 0,01834935 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,01116885 0,01833702 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,01116885 0,01832471 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,01116885 0,01831241 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,01116885 0,01830013 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,01116885 0,01828786 ! cerebral cortex development GO:0021987 40 19 0,000 0,01116885 0,01827561 ! pigmentation during development GO:0048066 42 19 0,000 0,01116885 0,01826338 ! response to vitamin A GO:0033189 32 19 0,000 0,01116885 0,01825116 ! heme metabolic process GO:0042168 40 19 0,000 0,01116885 0,01823896 ! neuromuscular junction development GO:0007528 43 19 0,000 0,01116885 0,01822678 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,01116885 0,01821461 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,01116885 0,01820246 ! response to fungus GO:0009620 26 19 0,000 0,01116885 0,01819033 ! peptide cross-linking GO:0018149 39 19 0,000 0,01116885 0,01817821 ! protein export from nucleus GO:0006611 40 19 0,000 0,01116885 0,01816611 ! heart process GO:0003015 32 19 0,000 0,01116885 0,01815402 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,01116885 0,01814195 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,01116885 0,01812989 ! visual learning GO:0008542 38 19 0,000 0,01116885 0,01811786 ! cellular pigmentation GO:0033059 37 19 0,000 0,01116885 0,01810583 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,01116885 0,01809383 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,01116885 0,01808184 ! vitamin transport GO:0051180 31 19 0,000 0,01116885 0,01806986 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,01116885 0,0180579 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,01116885 0,01804596 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,01116885 0,01803403 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,01116885 0,01802212 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,01116885 0,01801022 ! cilium assembly GO:0042384 38 19 0,000 0,01116885 0,01799834 ! peptide hormone secretion GO:0030072 32 19 0,000 0,01116885 0,01798648 ! protein secretion GO:0009306 45 20 0,000 0,01175338 0,01891535 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,01175338 0,0189029 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,01175338 0,01889046 ! positive regulation of ossification GO:0045778 50 20 0,000 0,01175338 0,01887804 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,01175338 0,01886564 ! skin development GO:0043588 42 20 0,000 0,01175338 0,01885325 ! phosphoinositide phosphorylation GO:0046854 40 20 0,000 0,01175338 0,01884088 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,01175338 0,01882852 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,01175338 0,01881619 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,01175338 0,01880386 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 0,000 0,01175338 0,01879156 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,01175338 0,01877927 ! response to vitamin GO:0033273 36 20 0,000 0,01175338 0,01876699 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,01175338 0,01875473 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,01175338 0,01874249 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,01175338 0,01873027 ! bile acid metabolic process GO:0008206 34 20 0,000 0,01175338 0,01871806 ! response to alkaloid GO:0043279 38 20 0,000 0,01175338 0,01870586 ! retinoid metabolic process GO:0001523 34 20 0,000 0,01175338 0,01869368 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,01175338 0,01868152 ! apoptotic mitochondrial changes GO:0008637 42 20 0,000 0,01175338 0,01866938 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,01175338 0,01865724 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,01175338 0,01864513 GO:0032392|DNA geometric change, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,01175338 0,01863303 ! actin filament bundle formation GO:0051017 47 20 0,000 0,01175338 0,01862095 ! body fluid secretion GO:0007589 33 20 0,000 0,01175338 0,01860888 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,01175338 0,01859683 ! peptide secretion GO:0002790 38 20 0,000 0,01175338 0,01858479 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,01175338 0,01857277 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,01175338 0,01856076 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,01175338 0,01854877 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,01175338 0,0185368 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,01175338 0,01852484 ! cell-cell junction organization GO:0045216 43 20 0,000 0,01175338 0,01851289 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,01175338 0,01850097 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,01175338 0,01848905 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,01175338 0,01847716 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,01175338 0,01846527 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,01175338 0,01845341 ! regulation of glucose import GO:0046324 30 20 0,000 0,01175338 0,01844155 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,01175338 0,01842972 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,01175338 0,0184179 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,01175338 0,01840609 ! negative regulation of translation GO:0017148 32 20 0,000 0,01175338 0,0183943 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,01175338 0,01838252 ! regulation of cell killing GO:0031341 46 21 0,000 0,01233758 0,01928388 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,01233758 0,01927155 ! hormone secretion GO:0046879 39 21 0,000 0,01233758 0,01925924 ! lipid phosphorylation GO:0046834 43 21 0,000 0,01233758 0,01924694 ! cAMP metabolic process GO:0046058 41 21 0,000 0,01233758 0,01923465 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,01233758 0,01922239 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,01233758 0,01921014 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,01233758 0,0191979 ! ovarian follicle development GO:0001541 39 21 0,000 0,01233758 0,01918568 ! smooth muscle contraction GO:0006939 48 21 0,000 0,01233758 0,01917348 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 0,000 0,01233758 0,01916129 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,01233758 0,01914911 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,01233758 0,01913695 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,01233758 0,01912481 ! plasma membrane fusion GO:0045026 33 21 0,000 0,01233758 0,01911268 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,01233758 0,01910057 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,01233758 0,01908848 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,01233758 0,01907639 ! sensory perception of pain GO:0019233 33 21 0,000 0,01233758 0,01906433 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,01233758 0,01905228 ! diencephalon development GO:0021536 36 21 0,000 0,01233758 0,01904024 ! collagen fibril organization GO:0030199 62 21 0,000 0,01233758 0,01902822 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,01233758 0,01901622 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,01233758 0,01900423 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,01233758 0,01899225 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,01233758 0,01898029 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,01233758 0,01896835 ! collagen catabolic process GO:0030574 29 21 0,000 0,01233758 0,01895642 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,01233758 0,0189445 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,01233758 0,0189326 ! sperm-egg recognition GO:0035036 23 21 0,000 0,01233758 0,01892072 ! actin filament-based movement GO:0030048 47 21 0,000 0,01233758 0,01890885 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,01233758 0,01889699 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,01292145 0,01977889 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,01292145 0,0197665 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,01292145 0,01975413 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,01292145 0,01974178 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,01292145 0,01972944 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,01292145 0,01971712 ! microtubule-based transport GO:0010970 59 22 0,000 0,01292145 0,01970481 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,01292145 0,01969252 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,01292145 0,01968024 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,01292145 0,01966798 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,01292145 0,01965573 ! cellular response to starvation GO:0009267 37 22 0,000 0,01292145 0,0196435 ! vacuolar transport GO:0007034 41 22 0,000 0,01292145 0,01963128 ! central nervous system neuron development GO:0021954 47 22 0,000 0,01292145 0,01961908 ! fucose metabolic process GO:0006004 44 22 0,000 0,01292145 0,0196069 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,01292145 0,01959473 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,01292145 0,01958257 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,01292145 0,01957043 ! ureteric bud development GO:0001657 50 22 0,000 0,01292145 0,01955831 ! cell aging GO:0007569 48 22 0,000 0,01292145 0,01954619 ! stem cell differentiation GO:0048863 57 22 0,000 0,01292145 0,0195341 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,01292145 0,01952202 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,01292145 0,01950995 ! cytolysis GO:0019835 27 22 0,000 0,01292145 0,0194979 ! renal system process GO:0003014 42 22 0,000 0,01292145 0,01948587 ! vasodilation GO:0042311 40 22 0,000 0,01292145 0,01947385 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,01292145 0,01946184 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,01292145 0,01944985 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 0,01292145 0,01943787 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,01292145 0,01942591 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,01292145 0,01941396 ! positive regulation of intracellular transport GO:0032388 42 22 0,000 0,01292145 0,01940203 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,01292145 0,01939011 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,01292145 0,01937821 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,01292145 0,01936632 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,01292145 0,01935445 ! sarcomere organization GO:0045214 32 22 0,000 0,01292145 0,01934259 ! positive regulation of B cell activation GO:0050871 42 22 0,000 0,01292145 0,01933074 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,01292145 0,01931891 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,01292145 0,0193071 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,01292145 0,0192953 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,01292145 0,01928351 ! gut development GO:0048565 44 22 0,000 0,01292145 0,01927174 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,01292145 0,01925998 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,01292145 0,01924823 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,01292145 0,01923651 ! protein stabilization GO:0050821 41 22 0,000 0,01292145 0,01922479 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,01350499 0,02008077 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,01350499 0,02006855 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,01350499 0,02005635 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,01350499 0,02004417 ! gluconeogenesis GO:0006094 38 23 0,000 0,01350499 0,020032 ! glycerol metabolic process GO:0006071 40 23 0,000 0,01350499 0,02001984 ! viral genome replication GO:0019079 44 23 0,000 0,01350499 0,0200077 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,01350499 0,01999558 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,01350499 0,01998347 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,01350499 0,01997137 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,01350499 0,01995929 ! regeneration GO:0031099 42 23 0,000 0,01350499 0,01994722 ! axis specification GO:0009798 43 23 0,000 0,01350499 0,01993517 ! visual behavior GO:0007632 46 23 0,000 0,01350499 0,01992313 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,01350499 0,01991111 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 0,01350499 0,0198991 ! response to ethanol GO:0045471 47 23 0,000 0,01350499 0,0198871 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,01350499 0,01987512 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,01350499 0,01986316 ! peroxisome organization GO:0007031 43 23 0,000 0,01350499 0,0198512 ! lysosome organization GO:0007040 47 23 0,000 0,01350499 0,01983927 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,01350499 0,01982735 ! vesicle targeting GO:0006903 49 23 0,000 0,01350499 0,01981544 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,01350499 0,01980354 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,01350499 0,01979166 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,01350499 0,0197798 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,01350499 0,01976795 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,01350499 0,01975611 ! DNA modification GO:0006304 36 23 0,000 0,01350499 0,01974429 ! fatty acid transport GO:0015908 47 23 0,000 0,01350499 0,01973248 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,01350499 0,01972068 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,01350499 0,0197089 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,01350499 0,01969714 ! hormone transport GO:0009914 41 23 0,000 0,01350499 0,01968538 ! cell-cell recognition GO:0009988 28 23 0,000 0,01350499 0,01967365 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,01350499 0,01966192 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,01350499 0,01965021 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,01350499 0,01963851 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,01408821 0,02047442 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,01408821 0,02046225 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,01408821 0,02045009 ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,01408821 0,02043794 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,01408821 0,02042581 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,01408821 0,0204137 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,01408821 0,0204016 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,01408821 0,02038951 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,01408821 0,02037744 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,01408821 0,02036538 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,01408821 0,02035334 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 0,000 0,01408821 0,02034131 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,01408821 0,0203293 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,01408821 0,0203173 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,01408821 0,02030531 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,01408821 0,02029334 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,01408821 0,02028138 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,01408821 0,02026943 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,01408821 0,0202575 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,01408821 0,02024559 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,01408821 0,02023368 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,01408821 0,0202218 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,01408821 0,02020992 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,01408821 0,02019806 ! membrane depolarization GO:0051899 45 24 0,000 0,01408821 0,02018622 ! pallium development GO:0021543 56 24 0,000 0,01408821 0,02017438 ! oogenesis GO:0048477 44 24 0,000 0,01408821 0,02016256 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,01408821 0,02015076 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,01408821 0,02013897 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 0,01408821 0,02012719 ! platelet activation GO:0030168 41 24 0,000 0,01408821 0,02011543 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,01408821 0,02010368 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,01408821 0,02009194 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,01408821 0,02008022 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,01408821 0,02006851 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,01408821 0,02005682 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,01408821 0,02004514 ! regulation of amine transport GO:0051952 41 24 0,000 0,01408821 0,02003347 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,01408821 0,02002181 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,0146711 0,02083808 ! positive regulation of fibroblast proliferation GO:0048146 48 25 0,000 0,0146711 0,02082597 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,0146711 0,02081387 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 0,000 0,0146711 0,02080179 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,0146711 0,02078973 ! leukocyte adhesion GO:0007159 55 25 0,000 0,0146711 0,02077768 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,0146711 0,02076564 ! phototransduction GO:0007602 37 25 0,000 0,0146711 0,02075361 ! keratinization GO:0031424 37 25 0,000 0,0146711 0,0207416 ! vasculogenesis GO:0001570 49 25 0,000 0,0146711 0,02072961 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,0146711 0,02071762 ! vacuole organization GO:0007033 49 25 0,000 0,0146711 0,02070566 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,0146711 0,0206937 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,0146711 0,02068176 ! receptor metabolic process GO:0043112 53 25 0,000 0,0146711 0,02066983 ! chromosome condensation GO:0030261 48 25 0,000 0,0146711 0,02065792 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,0146711 0,02064602 ! regulation of behavior GO:0050795 48 25 0,000 0,0146711 0,02063413 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,0146711 0,02062226 ! interaction with host GO:0051701 66 25 0,000 0,0146711 0,0206104 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,0146711 0,02059856 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,0146711 0,02058673 ! immunoglobulin production GO:0002377 62 25 0,000 0,0146711 0,02057491 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,0146711 0,0205631 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,0146711 0,02055131 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,0146711 0,02053954 ! liver development GO:0001889 55 25 0,000 0,0146711 0,02052777 ! protein tetramerization GO:0051262 57 25 0,000 0,0146711 0,02051602 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,01525366 0,02131847 ! myelination GO:0042552 50 26 0,000 0,01525366 0,02130628 ! initiation of viral infection GO:0019059 60 26 0,000 0,01525366 0,0212941 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,01525366 0,02128194 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,01525366 0,0212698 ! molting cycle process GO:0022404 52 26 0,000 0,01525366 0,02125766 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,01525366 0,02124554 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,01525366 0,02123344 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,01525366 0,02122135 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,01525366 0,02120927 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,01525366 0,0211972 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,01525366 0,02118515 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,01525366 0,02117311 ! digestive system process GO:0022600 49 26 0,000 0,01525366 0,02116109 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,01525366 0,02114908 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,01525366 0,02113709 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,01525366 0,0211251 ! osteoblast differentiation GO:0001649 63 26 0,000 0,01525366 0,02111313 ! neural crest cell development GO:0014032 59 26 0,000 0,01525366 0,02110118 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,01525366 0,02108924 ! negative regulation of cell development GO:0010721 83 26 0,000 0,01525366 0,02107731 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,01525366 0,02106539 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,01525366 0,02105349 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,01525366 0,0210416 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,01525366 0,02102973 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,01525366 0,02101787 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,01525366 0,02100602 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,01525366 0,02099419 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,01525366 0,02098237 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,01525366 0,02097056 ! blastocyst development GO:0001824 50 26 0,000 0,01525366 0,02095876 ! telomere organization GO:0032200 46 26 0,000 0,01525366 0,02094698 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,01525366 0,02093521 ! neural tube closure GO:0001843 58 26 0,000 0,01525366 0,02092346 GO:0060606|tube closure, ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,01525366 0,02091172 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,01525366 0,02089999 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,01583589 0,02168558 ! embryonic pattern specification GO:0009880 49 27 0,000 0,01583589 0,02167343 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,01583589 0,02166129 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,01583589 0,02164917 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,01583589 0,02163706 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,01583589 0,02162497 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,01583589 0,02161289 ! iron ion transport GO:0006826 65 27 0,000 0,01583589 0,02160082 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,01583589 0,02158877 ! superoxide metabolic process GO:0006801 41 27 0,000 0,01583589 0,02157673 ! tube lumen formation GO:0035148 59 27 0,000 0,01583589 0,0215647 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,01583589 0,02155269 ! insulin receptor signaling pathway GO:0008286 66 27 0,000 0,01583589 0,02154069 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,01583589 0,0215287 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,01583589 0,02151673 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,01583589 0,02150476 ! response to starvation GO:0042594 47 27 0,000 0,01583589 0,02149282 ! response to toxin GO:0009636 49 27 0,000 0,01583589 0,02148088 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,01583589 0,02146896 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,01583589 0,02145706 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,01583589 0,02144516 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,01583589 0,02143328 ! leukocyte proliferation GO:0070661 59 27 0,000 0,01583589 0,02142141 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,01583589 0,02140956 ! regulation of fibroblast proliferation GO:0048145 56 28 0,000 0,01641779 0,02218399 ! neuron fate commitment GO:0048663 52 28 0,000 0,01641779 0,02217173 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 0,000 0,01641779 0,02215948 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,01641779 0,02214725 ! protein amino acid acylation GO:0043543 59 28 0,000 0,01641779 0,02213502 ! vesicle docking GO:0048278 55 28 0,000 0,01641779 0,02212281 ! circadian rhythm GO:0007623 56 28 0,000 0,01641779 0,02211062 ! dendrite development GO:0016358 67 28 0,000 0,01641779 0,02209844 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,01641779 0,02208627 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,01641779 0,02207411 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,01641779 0,02206197 ! base-excision repair GO:0006284 41 28 0,000 0,01641779 0,02204984 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,01641779 0,02203773 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,01641779 0,02202562 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,01641779 0,02201354 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,01641779 0,02200146 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,01641779 0,0219894 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,01641779 0,02197735 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,01641779 0,02196531 ! glutathione metabolic process GO:0006749 42 28 0,000 0,01641779 0,02195329 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,01641779 0,02194128 ! lipid oxidation GO:0034440 48 28 0,000 0,01641779 0,02192928 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,01641779 0,0219173 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,01641779 0,02190533 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,01699937 0,02266891 ! translational initiation GO:0006413 66 29 0,000 0,01699937 0,02265655 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,01699937 0,02264419 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,01699937 0,02263185 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,01699937 0,02261953 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,01699937 0,02260721 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,01699937 0,02259491 ! primary neural tube formation GO:0014020 61 29 0,000 0,01699937 0,02258263 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,01699937 0,02257035 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,01699937 0,02255809 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,01699937 0,02254585 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,01699937 0,02253361 ! somitogenesis GO:0001756 52 29 0,000 0,01699937 0,02252139 ! synaptogenesis GO:0007416 46 29 0,000 0,01699937 0,02250919 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,01699937 0,02249699 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,01699937 0,02248481 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,01699937 0,02247265 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,01699937 0,02246049 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,01758061 0,02321591 ! phenol metabolic process GO:0018958 56 30 0,000 0,01758061 0,02320337 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,01758061 0,02319084 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,01758061 0,02317833 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,01758061 0,02316582 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,01758061 0,02315334 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,01758061 0,02314086 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,01758061 0,0231284 ! acute-phase response GO:0006953 50 30 0,000 0,01758061 0,02311595 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,01758061 0,02310352 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,01758061 0,0230911 ! myofibril assembly GO:0030239 50 30 0,000 0,01758061 0,02307869 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,01758061 0,02306629 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,01758061 0,02305391 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,01758061 0,02304154 ! cell fate determination GO:0001709 64 30 0,000 0,01758061 0,02302919 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,01758061 0,02301685 ! phospholipid transport GO:0015914 65 30 0,000 0,01758061 0,02300452 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,01758061 0,0229922 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,01758061 0,0229799 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,01758061 0,02296761 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,01758061 0,02295534 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,01758061 0,02294308 GO:0048871|multicellular organismal homeostasis, ! regulation of B cell activation GO:0050864 55 30 0,000 0,01758061 0,02293083 ! regulation of coagulation GO:0050818 52 30 0,000 0,01758061 0,02291859 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,01816153 0,02366327 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,01816153 0,02365065 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,01816153 0,02363805 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,01816153 0,02362547 ! cell junction assembly GO:0034329 85 31 0,000 0,01816153 0,02361289 ! regulation of innate immune response GO:0045088 57 31 0,000 0,01816153 0,02360033 ! ovulation cycle process GO:0022602 55 31 0,000 0,01816153 0,02358779 ! peptide transport GO:0015833 60 31 0,000 0,01816153 0,02357525 ! male gonad development GO:0008584 56 31 0,000 0,01816153 0,02356273 ! iron ion homeostasis GO:0055072 60 31 0,000 0,01816153 0,02355023 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,01816153 0,02353773 ! detection of light stimulus GO:0009583 44 31 0,000 0,01816153 0,02352525 ! cellular response to extracellular stimulus GO:0031668 52 31 0,000 0,01816153 0,02351279 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,01816153 0,02350033 ! natural killer cell activation GO:0030101 50 31 0,000 0,01816153 0,02348789 ! ensheathment of neurons GO:0007272 64 31 0,000 0,01816153 0,02347546 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,01816153 0,02346305 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,01816153 0,02345065 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,01816153 0,02343826 ! eye morphogenesis GO:0048592 65 31 0,000 0,01816153 0,02342588 ! response to heat GO:0009408 54 31 0,000 0,01816153 0,02341352 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,01816153 0,02340117 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,01874213 0,02413654 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,01874213 0,02412382 ! collagen metabolic process GO:0032963 49 32 0,000 0,01874213 0,02411112 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,01874213 0,02409843 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,01874213 0,02408575 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,01874213 0,02407309 ! metanephros development GO:0001656 81 32 0,000 0,01874213 0,02406044 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,01874213 0,0240478 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,01874213 0,02403518 ! muscle cell development GO:0055001 52 32 0,000 0,01874213 0,02402257 ! mesoderm formation GO:0001707 73 32 0,000 0,01874213 0,02400997 ! ovulation cycle GO:0042698 57 32 0,000 0,01874213 0,02399739 ! peripheral nervous system development GO:0007422 68 32 0,000 0,01874213 0,02398482 ! BMP signaling pathway GO:0030509 71 32 0,000 0,01874213 0,02397226 ! hindbrain development GO:0030902 65 32 0,000 0,01874213 0,02395971 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,01874213 0,02394718 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,01874213 0,02393467 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,01874213 0,02392216 ! gene silencing GO:0016458 71 32 0,000 0,01874213 0,02390967 ! regulation of pH GO:0006885 56 33 0,000 0,01932239 0,02463706 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,01932239 0,02462421 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,01932239 0,02461137 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,01932239 0,02459854 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,01932239 0,02458573 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,01932239 0,02457293 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,01932239 0,02456015 ! response to ionizing radiation GO:0010212 74 33 0,000 0,01932239 0,02454738 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,01932239 0,02453462 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,01932239 0,02452187 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,01932239 0,02450914 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,01932239 0,02449642 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,01932239 0,02448372 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,01932239 0,02447102 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,01932239 0,02445834 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,01990233 0,02517939 ! glial cell differentiation GO:0010001 67 34 0,000 0,01990233 0,02516635 ! post-embryonic development GO:0009791 76 34 0,000 0,01990233 0,02515334 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,01990233 0,02514033 ! cholesterol transport GO:0030301 62 34 0,000 0,01990233 0,02512734 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,01990233 0,02511436 ! spliceosome assembly GO:0000245 75 34 0,000 0,01990233 0,02510139 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,01990233 0,02508844 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,01990233 0,0250755 ! formation of primary germ layer GO:0001704 76 34 0,000 0,01990233 0,02506258 ! cell fate specification GO:0001708 56 34 0,000 0,01990233 0,02504966 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,01990233 0,02503677 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,01990233 0,02502388 ! adult locomotory behavior GO:0008344 62 34 0,000 0,01990233 0,02501101 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,01990233 0,02499815 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,02048195 0,02571295 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,02048195 0,02569974 ! negative regulation of secretion GO:0051048 68 35 0,000 0,02048195 0,02568655 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,02048195 0,02567337 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,02048195 0,0256602 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,02048195 0,02564705 ! membrane docking GO:0022406 69 35 0,000 0,02048195 0,02563391 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,02048195 0,02562078 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,02048195 0,02560767 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,02048195 0,02559457 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,02048195 0,02558149 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,02048195 0,02556842 ! ceramide metabolic process GO:0006672 72 35 0,000 0,02048195 0,02555536 ! telencephalon development GO:0021537 81 35 0,000 0,02048195 0,02554231 ! sterol transport GO:0015918 63 35 0,000 0,02048195 0,02552928 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,02048195 0,02551626 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,02048195 0,02550326 ! placenta development GO:0001890 53 35 0,000 0,02048195 0,02549027 ! vesicle localization GO:0051648 70 35 0,000 0,02048195 0,02547729 ! regulation of muscle development GO:0048634 82 36 0,000 0,02106123 0,02618452 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,02106123 0,0261712 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,02106123 0,0261579 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,02106123 0,02614461 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,02106123 0,02613133 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,02106123 0,02611807 ! positive regulation of cell development GO:0010720 85 36 0,000 0,02106123 0,02610481 ! protein targeting to membrane GO:0006612 75 36 0,000 0,02106123 0,02609158 ! regulation of proteolysis GO:0030162 77 36 0,000 0,02106123 0,02607835 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,02106123 0,02606514 ! aerobic respiration GO:0009060 56 36 0,000 0,02106123 0,02605194 ! cytokine production GO:0001816 68 36 0,000 0,02106123 0,02603876 ! embryonic organ development GO:0048568 67 36 0,000 0,02106123 0,02602559 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,02106123 0,02601243 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,02164019 0,02671399 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,02164019 0,0267005 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,02164019 0,02668702 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,02164019 0,02667356 ! sister chromatid segregation GO:0000819 65 37 0,000 0,02164019 0,0266601 ! odontogenesis GO:0042476 74 37 0,000 0,02164019 0,02664667 ! actomyosin structure organization GO:0031032 68 37 0,000 0,02164019 0,02663324 ! cell junction organization GO:0034330 96 37 0,000 0,02164019 0,02661983 ! tissue remodeling GO:0048771 78 37 0,000 0,02164019 0,02660644 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,02164019 0,02659305 ! female gonad development GO:0008585 71 37 0,000 0,02164019 0,02657968 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,02164019 0,02656633 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,02164019 0,02655298 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,02164019 0,02653965 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,02164019 0,02652634 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,02221883 0,02722196 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,02221883 0,02720832 ! meiosis I GO:0007127 74 38 0,000 0,02221883 0,02719468 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,02221883 0,02718107 ! organic anion transport GO:0015711 82 38 0,000 0,02221883 0,02716746 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,02221883 0,02715387 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,02221883 0,0271403 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,02221883 0,02712673 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,02221883 0,02711318 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,02221883 0,02709965 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,02221883 0,02708612 ! regulation of protein stability GO:0031647 77 38 0,000 0,02221883 0,02707261 ! spermatid development GO:0007286 69 38 0,000 0,02221883 0,02705912 ! glycogen metabolic process GO:0005977 63 38 0,000 0,02221883 0,02704564 ! pigment metabolic process GO:0042440 87 38 0,000 0,02221883 0,02703217 ! cellular response to insulin stimulus GO:0032869 85 38 0,000 0,02221883 0,02701871 ! neural tube formation GO:0001841 79 38 0,000 0,02221883 0,02700527 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,02279713 0,02769438 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,02279713 0,02768061 ! negative regulation of binding GO:0051100 71 39 0,000 0,02279713 0,02766686 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,02279713 0,02765313 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,02279713 0,0276394 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,02279713 0,02762569 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,02279713 0,027612 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,02279713 0,02759831 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,02279713 0,02758464 ! positive regulation of leukocyte proliferation GO:0070665 70 39 0,000 0,02279713 0,02757099 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,02279713 0,02755735 ! glucan metabolic process GO:0044042 64 39 0,000 0,02279713 0,02754372 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,02337512 0,02822808 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 0,000 0,02337512 0,02821413 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,02337512 0,0282002 ! learning GO:0007612 82 40 0,000 0,02337512 0,02818628 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,02337512 0,02817238 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,02337512 0,02815849 ! lipid homeostasis GO:0055088 75 40 0,000 0,02337512 0,02814461 ! mismatch repair GO:0006298 58 40 0,000 0,02337512 0,02813074 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,02337512 0,02811689 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,02337512 0,02810306 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,02337512 0,02808923 ! RNA export from nucleus GO:0006405 61 41 0,000 0,02395277 0,02876923 ! mRNA catabolic process GO:0006402 79 41 0,000 0,02395277 0,0287551 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,02395277 0,02874097 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,02395277 0,02872686 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,02395277 0,02871277 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,02395277 0,02869869 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,02395277 0,02868462 ! gliogenesis GO:0042063 91 41 0,000 0,02395277 0,02867056 ! feeding behavior GO:0007631 69 41 0,000 0,02395277 0,02865652 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,02395277 0,0286425 ! mesenchymal cell development GO:0014031 94 41 0,000 0,02395277 0,02862848 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,02395277 0,02861449 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,02395277 0,0286005 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,02395277 0,02858653 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,02395277 0,02857257 ! RNA modification GO:0009451 64 41 0,000 0,02395277 0,02855863 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,0245301 0,0292327 ! ear morphogenesis GO:0042471 64 42 0,000 0,0245301 0,02921845 ! organic ether metabolic process GO:0018904 59 42 0,000 0,0245301 0,02920421 ! regulation of intracellular protein transport GO:0033157 86 42 0,000 0,0245301 0,02918999 ! T cell differentiation GO:0030217 93 42 0,000 0,0245301 0,02917578 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,0245301 0,02916158 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,0245301 0,02914739 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,0245301 0,02913322 ! regulation of protein secretion GO:0050708 77 42 0,000 0,0245301 0,02911907 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,0245301 0,02910493 ! cytokinesis GO:0000910 84 42 0,000 0,0245301 0,0290908 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,0245301 0,02907668 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,02510711 0,0297462 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 0,000 0,02510711 0,02973178 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,02510711 0,02971738 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,02510711 0,02970299 ! regulation of tube size GO:0035150 76 43 0,000 0,02510711 0,02968861 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,02510711 0,02967425 ! glucose transport GO:0015758 66 43 0,000 0,02510711 0,0296599 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,02510711 0,02964556 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,02510711 0,02963124 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,02510711 0,02961693 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,02510711 0,02960264 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,02510711 0,02958836 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,02510711 0,02957409 ! segmentation GO:0035282 78 43 0,000 0,02510711 0,02955984 ! ion transmembrane transport GO:0034220 79 43 0,000 0,02510711 0,0295456 ! neuron migration GO:0001764 85 43 0,000 0,02510711 0,02953138 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,02510711 0,02951717 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,02568379 0,03018062 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,02568379 0,03016611 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,02568379 0,03015161 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,02568379 0,03013713 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,02568379 0,03012266 ! hexose transport GO:0008645 68 44 0,000 0,02568379 0,03010821 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,02568379 0,03009377 ! striated muscle contraction GO:0006941 85 44 0,000 0,02568379 0,03007934 ! phagocytosis GO:0006909 105 44 0,000 0,02568379 0,03006493 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,02568379 0,03005053 ! double-strand break repair GO:0006302 85 44 0,000 0,02568379 0,03003614 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,02626015 0,03069547 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,02626015 0,03068079 ! regulation of epithelial cell proliferation GO:0050678 122 45 0,000 0,02626015 0,03066613 ! induction of apoptosis by intracellular signals GO:0008629 95 45 0,000 0,02626015 0,03065148 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,02626015 0,03063684 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,02626015 0,03062221 ! biopolymer methylation GO:0043414 91 45 0,000 0,02626015 0,0306076 ! B cell differentiation GO:0030183 124 45 0,000 0,02626015 0,03059301 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,02626015 0,03057843 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,02626015 0,03056386 ! developmental growth GO:0048589 88 45 0,000 0,02626015 0,0305493 ! maintenance of location in cell GO:0051651 101 45 0,000 0,02626015 0,03053476 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,02683618 0,03118972 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,02683618 0,03117488 ! glycolysis GO:0006096 71 46 0,000 0,02683618 0,03116007 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 0,000 0,02683618 0,03114527 ! regulation of gene-specific transcription GO:0032583 102 46 0,000 0,02683618 0,03113048 ! leukocyte migration GO:0050900 75 46 0,000 0,02683618 0,0311157 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,02683618 0,03110094 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,02683618 0,03108619 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,02683618 0,03107146 ! pigmentation GO:0043473 103 46 0,000 0,02683618 0,03105674 ! cell growth GO:0016049 90 46 0,000 0,02683618 0,03104204 ! positive regulation of protein transport GO:0051222 80 46 0,000 0,02683618 0,03102735 ! neural tube development GO:0021915 91 47 0,000 0,02741188 0,03167797 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,02741188 0,031663 ! response to insulin stimulus GO:0032868 98 47 0,000 0,02741188 0,03164803 ! positive regulation of defense response GO:0031349 88 48 0,000 0,02798727 0,03229707 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,02798727 0,03228182 ! mitochondrial transport GO:0006839 94 48 0,000 0,02798727 0,03226659 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,02798727 0,03225137 ! cellular component disassembly GO:0022411 89 48 0,000 0,02798727 0,03223616 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,02798727 0,03222097 ! endosome transport GO:0016197 127 48 0,000 0,02798727 0,03220579 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,02798727 0,03219063 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,02798727 0,03217548 ! male sex differentiation GO:0046661 93 48 0,000 0,02798727 0,03216035 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,02798727 0,03214523 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,02798727 0,03213012 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,02798727 0,03211503 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,02798727 0,03209995 ! methylation GO:0032259 97 48 0,000 0,02798727 0,03208489 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,02856233 0,03272878 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,02856233 0,03271344 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,02856233 0,03269811 ! JNK cascade GO:0007254 106 49 0,000 0,02856233 0,03268279 ! regulation of mast cell proliferation GO:0070666 89 49 0,000 0,02856233 0,03266749 ! protein homooligomerization GO:0051260 84 49 0,000 0,02856233 0,0326522 ! regulation of action potential GO:0001508 102 50 0,000 0,02913706 0,03329366 ! regulation of ion transport GO:0043269 86 50 0,000 0,02913706 0,03327809 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,02913706 0,03326254 ! endocrine system development GO:0035270 109 50 0,000 0,02913706 0,033247 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,02913706 0,03323148 ! activation of caspase activity GO:0006919 95 50 0,000 0,02913706 0,03321598 ! regulation of ossification GO:0030278 123 50 0,000 0,02913706 0,03320048 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,02913706 0,03318501 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,02913706 0,03316954 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,02913706 0,03315409 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,02913706 0,03313866 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,02913706 0,03312324 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,02971147 0,03376052 ! viral infectious cycle GO:0019058 104 51 0,000 0,02971147 0,03374483 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,02971147 0,03372915 ! peptide metabolic process GO:0006518 80 51 0,000 0,02971147 0,03371348 ! response to temperature stimulus GO:0009266 84 51 0,000 0,02971147 0,03369783 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,02971147 0,03368219 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,02971147 0,03366657 ! positive regulation of binding GO:0051099 88 52 0,000 0,03028556 0,03430117 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,03028556 0,03428527 ! Notch signaling pathway GO:0007219 111 52 0,000 0,03028556 0,03426939 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,03028556 0,03425353 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,03028556 0,03423767 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,03028556 0,03422184 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,03028556 0,03420602 ! excretion GO:0007588 87 52 0,000 0,03028556 0,03419021 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,03028556 0,03417442 ! histone modification GO:0016570 104 52 0,000 0,03028556 0,03415864 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,03028556 0,03414288 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,03028556 0,03412713 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,03028556 0,03411139 ! amino acid activation GO:0043038 98 52 0,000 0,03028556 0,03409568 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,03085932 0,03472562 ! positive regulation of growth GO:0045927 96 53 0,000 0,03085932 0,03470963 ! inner ear development GO:0048839 89 53 0,000 0,03085932 0,03469366 ! chromatin remodeling GO:0006338 122 53 0,000 0,03085932 0,0346777 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,03085932 0,03466176 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,03085932 0,03464583 ! vesicle organization GO:0016050 127 53 0,000 0,03085932 0,03462991 ! regulation of leukocyte proliferation GO:0070663 97 53 0,000 0,03085932 0,03461401 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,03085932 0,03459813 ! cartilage development GO:0051216 99 53 0,000 0,03085932 0,03458226 ! synapse organization GO:0050808 102 53 0,000 0,03085932 0,0345664 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,03143276 0,03519259 ! regulation of translational initiation GO:0006446 87 54 0,000 0,03143276 0,03517647 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,03143276 0,03516036 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,03143276 0,03514427 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 0,000 0,03143276 0,03512819 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,03143276 0,03511213 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,03143276 0,03509608 ! membrane fusion GO:0006944 122 54 0,000 0,03143276 0,03508005 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,03143276 0,03506403 ! covalent chromatin modification GO:0016569 115 54 0,000 0,03143276 0,03504803 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,03143276 0,03503204 ! regulation of cell shape GO:0008360 142 54 0,000 0,03143276 0,03501607 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,03143276 0,03500011 ! RNA catabolic process GO:0006401 103 55 0,000 0,03200588 0,03562203 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,03200588 0,03560581 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,03200588 0,0355896 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,03200588 0,03557341 ! cell recognition GO:0008037 98 55 0,000 0,03200588 0,03555723 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,03200588 0,03554107 ! cell maturation GO:0048469 107 55 0,000 0,03200588 0,03552492 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,03200588 0,03550879 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,03200588 0,03549267 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,03257867 0,03611148 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,03257867 0,0360951 ! glucose catabolic process GO:0006007 88 56 0,000 0,03257867 0,03607874 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,03257867 0,03606239 ! regulation of DNA replication GO:0006275 105 56 0,000 0,03257867 0,03604606 ! RNA elongation GO:0006354 90 56 0,000 0,03257867 0,03602974 ! chloride transport GO:0006821 102 57 0,000 0,03315114 0,03664626 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,03315114 0,03662969 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,03315114 0,03661313 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 131 57 0,000 0,03315114 0,03659658 ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,03315114 0,03658005 ! heart morphogenesis GO:0003007 105 57 0,000 0,03315114 0,03656354 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,03315114 0,03654704 ! regulation of intracellular transport GO:0032386 108 57 0,000 0,03315114 0,03653055 ! regulation of actin filament length GO:0030832 118 58 0,000 0,03372329 0,03714427 ! positive regulation of cell migration GO:0030335 137 58 0,000 0,03372329 0,03712753 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,03372329 0,03711081 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,03372329 0,0370941 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,03372329 0,03707741 ! aging GO:0007568 112 58 0,000 0,03372329 0,03706073 ! gastrulation GO:0007369 122 58 0,000 0,03372329 0,03704406 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,03372329 0,03702741 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,03372329 0,03701078 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,03372329 0,03699416 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,03372329 0,03697756 ! maintenance of location GO:0051235 124 58 0,000 0,03372329 0,03696097 ! nuclear export GO:0051168 110 59 0,000 0,03429512 0,03757084 ! establishment of organelle localization GO:0051656 122 59 0,000 0,03429512 0,037554 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,03486662 0,0381627 ! lipid modification GO:0030258 112 60 0,000 0,03486662 0,03814561 ! DNA catabolic process GO:0006308 94 60 0,000 0,03486662 0,03812854 ! regulation of endocytosis GO:0030100 104 60 0,000 0,03486662 0,03811148 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,03486662 0,03809443 ! adult behavior GO:0030534 104 60 0,000 0,03486662 0,0380774 ! kidney development GO:0001822 133 60 0,000 0,03486662 0,03806039 ! positive regulation of secretion GO:0051047 110 61 0,000 0,0354378 0,03866661 ! regulation of cellular component size GO:0032535 125 61 0,000 0,0354378 0,03864935 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,0354378 0,0386321 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,0354378 0,03861487 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,0354378 0,03859766 ! regulation of heart contraction GO:0008016 123 61 0,000 0,0354378 0,03858046 ! camera-type eye development GO:0043010 126 61 0,000 0,0354378 0,03856327 ! proton transport GO:0015992 117 61 0,000 0,0354378 0,0385461 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,0354378 0,03852895 ! viral reproductive process GO:0022415 132 62 0,000 0,03600866 0,03913219 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,03600866 0,03911479 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,03600866 0,0390974 ! tRNA processing GO:0008033 102 62 0,000 0,03600866 0,03908003 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,03600866 0,03906268 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,0365792 0,03966399 ! regulation of mitosis GO:0007088 112 63 0,000 0,0365792 0,0396464 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 0,000 0,0365792 0,03962882 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,0365792 0,03961125 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,0365792 0,0395937 ! hydrogen transport GO:0006818 121 64 0,000 0,03714941 0,0401931 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,03714941 0,04017531 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,03714941 0,04015753 ! protein amino acid autophosphorylation GO:0046777 157 64 0,000 0,03714941 0,04013977 ! response to peptide hormone stimulus GO:0043434 129 64 0,000 0,03714941 0,04012202 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,03771931 0,04071952 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,03771931 0,04070153 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,03771931 0,04068356 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,03771931 0,04066561 ! positive regulation of cell motion GO:0051272 157 65 0,000 0,03771931 0,04064767 ! ear development GO:0043583 114 66 0,000 0,03828888 0,04124327 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,03828888 0,04122509 ! gonad development GO:0008406 115 66 0,000 0,03828888 0,04120693 ! steroid hormone receptor signaling pathway GO:0030518 146 66 0,000 0,03828888 0,04118879 ! negative regulation of cell growth GO:0030308 142 67 0,000 0,03885813 0,04178276 ! activation of MAPK activity GO:0000187 124 67 0,000 0,03885813 0,04176437 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,03885813 0,04174601 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 0,000 0,03885813 0,04172766 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,03885813 0,04170932 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,03885813 0,04169101 ! secondary metabolic process GO:0019748 125 67 0,000 0,03885813 0,0416727 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,03885813 0,04165442 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,03942707 0,04224575 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,03942707 0,04222723 ! hexose catabolic process GO:0019320 113 68 0,000 0,03942707 0,04220873 ! extracellular matrix organization GO:0030198 146 68 0,000 0,03942707 0,04219024 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,03942707 0,04217177 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,03942707 0,04215331 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,03942707 0,04213487 ! viral reproduction GO:0016032 142 68 0,000 0,03942707 0,04211645 ! regulation of lipase activity GO:0060191 137 68 0,000 0,03942707 0,04209804 ! adaptive immune response GO:0002250 126 68 0,000 0,03942707 0,04207965 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cell projection assembly GO:0030031 138 68 0,000 0,03942707 0,04206128 ! negative regulation of cell size GO:0045792 144 69 0,000 0,03999568 0,04264925 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,03999568 0,04263064 ! negative regulation of protein kinase activity GO:0006469 144 69 0,000 0,03999568 0,04261205 ! lung development GO:0030324 165 69 0,000 0,03999568 0,04259348 ! urogenital system development GO:0001655 149 69 0,000 0,03999568 0,04257492 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,03999568 0,04255637 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 0,000 0,03999568 0,04253785 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,03999568 0,04251934 ! developmental maturation GO:0021700 128 69 0,000 0,03999568 0,04250084 ! single fertilization GO:0007338 83 69 0,000 0,03999568 0,04248236 ! negative regulation of kinase activity GO:0033673 145 70 0,000 0,04056397 0,04306726 ! cell redox homeostasis GO:0045454 114 70 0,000 0,04056397 0,04304855 ! germ cell development GO:0007281 133 70 0,000 0,04056397 0,04302986 ! activation of immune response GO:0002253 120 70 0,000 0,04056397 0,04301118 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,04056397 0,04299252 ! cell cycle checkpoint GO:0000075 145 71 0,000 0,04113194 0,04357559 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,04113194 0,04355671 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,04113194 0,04353783 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 0,000 0,04113194 0,04351898 ! appendage morphogenesis GO:0035107 150 72 0,000 0,04169959 0,04410047 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,04169959 0,04408139 ! respiratory tube development GO:0030323 171 72 0,000 0,04169959 0,04406232 ! actin filament organization GO:0007015 167 72 0,000 0,04169959 0,04404327 ! B cell activation GO:0042113 179 72 0,000 0,04169959 0,04402424 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,04169959 0,04400522 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,04169959 0,04398622 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,04169959 0,04396724 ! appendage development GO:0048736 151 73 0,000 0,04226691 0,04454619 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,04226691 0,04452698 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,04226691 0,04450779 ! regulation of immune effector process GO:0002697 156 73 0,000 0,04226691 0,04448861 ! acute inflammatory response GO:0002526 118 74 0,000 0,04283392 0,04506601 ! amino acid transport GO:0006865 148 74 0,000 0,04283392 0,04504661 ! regulation of caspase activity GO:0043281 136 74 0,000 0,04283392 0,04502723 ! negative regulation of transferase activity GO:0051348 155 74 0,000 0,04283392 0,04500786 ! respiratory system development GO:0060541 175 74 0,000 0,04283392 0,04498851 ! organelle localization GO:0051640 155 74 0,000 0,04283392 0,04496918 ! regulation of transcription factor activity GO:0051090 137 75 0,000 0,04340061 0,04554454 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 143 75 0,000 0,04340061 0,04552499 ! reproductive structure development GO:0048608 131 75 0,000 0,04340061 0,04550545 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,04340061 0,04548593 ! eye development GO:0001654 155 75 0,000 0,04340061 0,04546642 ! axon guidance GO:0007411 162 75 0,000 0,04340061 0,04544694 ! rhythmic process GO:0048511 142 75 0,000 0,04340061 0,04542746 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,04396698 0,04600057 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,04396698 0,04598088 ! learning or memory GO:0007611 161 76 0,000 0,04396698 0,04596121 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,04396698 0,04594155 ! regulation of blood pressure GO:0008217 134 76 0,000 0,04396698 0,04592191 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,04396698 0,04590228 ! amine catabolic process GO:0009310 136 77 0,000 0,04453304 0,04647339 ! neurotransmitter transport GO:0006836 142 77 0,000 0,04453304 0,04645355 ! phosphoinositide metabolic process GO:0030384 146 77 0,000 0,04453304 0,04643372 ! regulation of endopeptidase activity GO:0052548 141 77 0,000 0,04453304 0,04641391 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,04453304 0,04639412 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,04453304 0,04637434 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,04453304 0,04635458 ! regulation of catabolic process GO:0009894 173 77 0,000 0,04453304 0,04633484 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,04509877 0,04690349 ! antigen processing and presentation GO:0019882 117 78 0,000 0,04509877 0,04688353 ! fertilization GO:0009566 99 78 0,000 0,04509877 0,04686358 ! positive regulation of lymphocyte activation GO:0051251 142 78 0,000 0,04509877 0,04684366 ! blood coagulation GO:0007596 151 79 0,000 0,04566418 0,04741079 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,04566418 0,04739065 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,04566418 0,04737053 ! protein oligomerization GO:0051259 149 79 0,000 0,04566418 0,04735042 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,04566418 0,04733033 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,04622927 0,04789572 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,04622927 0,04787542 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,04622927 0,04785513 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,04622927 0,04783486 ! meiosis GO:0007126 143 81 0,000 0,04679405 0,04839876 GO:0051327|M phase of meiotic cell cycle, ! muscle cell differentiation GO:0042692 178 81 0,000 0,04679405 0,04837827 ! response to hypoxia GO:0001666 178 81 0,000 0,04679405 0,04835781 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,04679405 0,04833736 ! regulation of peptidase activity GO:0052547 150 82 0,000 0,04735851 0,04889976 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,04735851 0,0488791 ! protein import into nucleus GO:0006606 174 82 0,000 0,04735851 0,04885846 ! meiotic cell cycle GO:0051321 144 82 0,000 0,04735851 0,04883783 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,04792264 0,04939874 ! exocytosis GO:0006887 153 83 0,000 0,04792264 0,04937791 ! response to drug GO:0042493 149 83 0,000 0,04792264 0,04935709 ! response to oxygen levels GO:0070482 183 83 0,000 0,04792264 0,04933629 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,04792264 0,04931551 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,04792264 0,04929474 ! nuclear import GO:0051170 177 83 0,000 0,04792264 0,049274 ! inorganic anion transport GO:0015698 156 83 0,000 0,04792264 0,04925327 ! T cell activation GO:0042110 189 84 0,000 0,04848646 0,04981179 ! response to nutrient GO:0007584 135 84 0,000 0,04848646 0,04979085 ! digestion GO:0007586 130 84 0,000 0,04848646 0,04976993 ! hemostasis GO:0007599 165 85 0,000 0,04904997 0,0503272 ! negative regulation of transport GO:0051051 164 85 0,000 0,04904997 0,05030607 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,04904997 0,05028496 ! negative regulation of growth GO:0045926 168 85 0,000 0,04904997 0,05026387 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,04904997 0,05024279 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,04904997 0,05022174 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,04904997 0,0502007 ! cellular response to hormone stimulus GO:0032870 182 85 0,000 0,04904997 0,05017968 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,04961315 0,05073459 ! regulation of lyase activity GO:0051339 169 86 0,000 0,04961315 0,05071336 ! positive regulation of cell activation GO:0050867 161 86 0,000 0,04961315 0,05069215 GO:0002696|positive regulation of leukocyte activation, ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,05017602 0,05124582 ! mitochondrion organization GO:0007005 159 87 0,000 0,05017602 0,05122441 ! nucleosome assembly GO:0006334 126 87 0,000 0,05017602 0,05120301 ! regulation of protein transport GO:0051223 165 87 0,000 0,05017602 0,05118163 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 143 88 0,000 0,05073857 0,05173385 ! amine biosynthetic process GO:0009309 146 88 0,000 0,05073857 0,05171227 ! sensory perception of smell GO:0007608 117 88 0,000 0,05073857 0,05169071 ! chromatin assembly GO:0031497 128 88 0,000 0,05073857 0,05166916 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,05073857 0,05164763 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,0513008 0,05219819 ! regulation of DNA binding GO:0051101 167 89 0,000 0,0513008 0,05217646 ! tube morphogenesis GO:0035239 194 89 0,000 0,0513008 0,05215474 ! cellular defense response GO:0006968 123 89 0,000 0,0513008 0,05213305 ! protein localization in nucleus GO:0034504 192 89 0,000 0,0513008 0,05211137 ! regulation of neurological system process GO:0031644 175 89 0,000 0,0513008 0,05208971 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,05186271 0,05263839 ! regulation of cell cycle process GO:0010564 161 90 0,000 0,05186271 0,05261653 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,05242431 0,05316421 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! ossification GO:0001503 205 91 0,000 0,05242431 0,05314215 ! gland development GO:0048732 220 91 0,000 0,05242431 0,05312011 ! defense response to bacterium GO:0042742 112 91 0,000 0,05242431 0,05309809 ! bone development GO:0060348 206 92 0,000 0,05298559 0,05364434 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,05298559 0,05362212 ! regulation of cell adhesion GO:0030155 241 92 0,000 0,05298559 0,05359992 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,05354655 0,05414496 ! amine transport GO:0015837 181 93 0,000 0,05354655 0,05412256 ! positive regulation of MAP kinase activity GO:0043406 174 93 0,000 0,05354655 0,05410018 ! vitamin metabolic process GO:0006766 153 93 0,000 0,05354655 0,05407781 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,0541072 0,05462144 ! female pregnancy GO:0007565 166 94 0,000 0,0541072 0,05459888 ! sterol metabolic process GO:0016125 166 94 0,000 0,0541072 0,05457634 ! regulation of membrane potential GO:0042391 179 94 0,000 0,0541072 0,05455382 ! regulation of defense response GO:0031347 171 95 0,000 0,05466753 0,05509603 ! nucleosome organization GO:0034728 143 95 0,000 0,05466753 0,05507331 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,05466753 0,05505061 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,05466753 0,05502793 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,05466753 0,05500527 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,05466753 0,05498262 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,05466753 0,05495999 ! sex differentiation GO:0007548 171 96 0,000 0,05522755 0,05550017 ! regulation of T cell activation GO:0050863 175 96 0,000 0,05522755 0,05547734 ! regulation of DNA metabolic process GO:0051052 188 97 0,000 0,05578725 0,05601654 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,05578725 0,05599353 ! transcription initiation GO:0006352 171 97 0,000 0,05578725 0,05597053 ! regulation of protein localization GO:0032880 188 97 0,000 0,05578725 0,05594756 ! leukocyte differentiation GO:0002521 232 98 0,000 0,05634663 0,05648536 ! forebrain development GO:0030900 210 98 0,000 0,05634663 0,05646219 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,05634663 0,05643904 ! skeletal muscle tissue development GO:0007519 223 100 0,000 0,05746445 0,05753511 GO:0060538|skeletal muscle organ development, ! mRNA transport GO:0051028 185 100 0,000 0,05746445 0,05751153 ! positive regulation of immune response GO:0050778 175 100 0,000 0,05746445 0,05748798 ! hormone metabolic process GO:0042445 171 100 0,000 0,05746445 0,05746445