pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-b2/out-0.05-06-0.01-300-run-b2//th1-pval-1e-01-06-th2-pval-1e-02-02-th3-pval-1e-01-01-run-b2/go_data/2023-2-real-Zhang-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! alcohol catabolic process GO:0046164 104 80 6,000 3,556E-13 8,178E-10 ! carbohydrate catabolic process GO:0016052 121 93 6,000 1,054E-12 1,212E-09 ! glycolysis GO:0006096 53 44 4,000 3,417E-10 2,62E-07 ! glucose catabolic process GO:0006007 66 54 4,000 9,9E-10 5,692E-07 ! hexose catabolic process GO:0019320 82 64 4,000 2,374E-09 1,092E-06 ! monosaccharide catabolic process GO:0046365 91 71 4,000 4,039E-09 1,548E-06 ! polyol catabolic process GO:0046174 7 5 2,000 6,283E-09 2,064E-06 GO:0019405|alditol catabolic process, ! substrate-bound cell migration, cell extension GO:0006930 5 5 2,000 6,283E-09 1,806E-06 ! substrate-bound cell migration GO:0006929 10 9 2,000 5,266E-08 1,346E-05 ! cellular carbohydrate catabolic process GO:0044275 13 11 2,000 1,033E-07 2,376E-05 ! fructose metabolic process GO:0006000 20 16 2,000 3,497E-07 7,312E-05 ! alditol metabolic process GO:0019400 24 20 2,000 7,103E-07 1,361E-04 ! sperm motility GO:0030317 27 24 2,000 1,258E-06 2,226E-04 ! hexose biosynthetic process GO:0019319 35 29 2,000 2,265E-06 3,721E-04 ! monosaccharide biosynthetic process GO:0046364 38 32 2,000 3,07E-06 4,707E-04 ! polyol metabolic process GO:0019751 44 34 2,000 3,699E-06 5,318E-04 ! alcohol biosynthetic process GO:0046165 45 38 2,000 5,203E-06 7,04E-04 ! cell projection assembly GO:0030031 76 53 2,000 1,433E-05 1,831E-03 ! axon guidance GO:0007411 99 66 2,000 2,779E-05 3,364E-03 ! carbohydrate biosynthetic process GO:0016051 97 77 2,000 4,415E-05 5,077E-03 ! induction of apoptosis via death domain receptors GO:0008625 15 13 1,000 6,09E-05 6,67E-03 ! activation of pro-apoptotic gene products GO:0008633 36 21 1,000 1,633E-04 0,01706759 ! induction of apoptosis by extracellular signals GO:0008624 74 44 1,000 7,265E-04 0,07264536 ! activation of MAPK activity GO:0000187 84 59 1,000 1,303E-03 0,12491317 ! negative regulation of cell growth GO:0030308 106 62 1,000 1,438E-03 0,13232019 ! negative regulation of cell size GO:0045792 108 64 1,000 1,532E-03 0,13549665 ! negative regulation of growth GO:0045926 123 75 1,000 2,096E-03 0,17855142 ! positive regulation of MAP kinase activity GO:0043406 121 85 1,000 2,682E-03 0,22032267 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 1,000 3,476E-03 0,27566818 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 4,568E-03 0,35023544 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 4,568E-03 0,33893753 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 4,568E-03 0,32834573 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 4,568E-03 0,31839586 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 4,568E-03 0,30903127 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 4,568E-03 0,30020181 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 4,568E-03 0,29186287 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 4,568E-03 0,28397469 ! sleep GO:0030431 11 5 0,000 4,568E-03 0,27650167 ! negative regulation of bone resorption GO:0045779 10 5 0,000 4,568E-03 0,26941188 ! nucleotide-sugar transport GO:0015780 8 5 0,000 4,568E-03 0,26267658 ! regulation of interferon-beta production GO:0032648 5 5 0,000 4,568E-03 0,25626984 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 4,568E-03 0,25016817 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 4,568E-03 0,24435031 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 4,568E-03 0,23879689 ! tongue development GO:0043586 6 5 0,000 4,568E-03 0,2334903 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 4,568E-03 0,22841442 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 4,568E-03 0,22355454 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 4,568E-03 0,21889715 ! cobalt ion transport GO:0006824 9 5 0,000 4,568E-03 0,21442986 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 4,568E-03 0,21014127 ! SMAD protein complex assembly GO:0007183 9 5 0,000 4,568E-03 0,20602085 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 4,568E-03 0,20205891 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 4,568E-03 0,19824648 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 4,568E-03 0,19457525 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 4,568E-03 0,19103752 ! embryonic camera-type eye development GO:0031076 8 5 0,000 4,568E-03 0,18762613 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 4,568E-03 0,18433444 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 4,568E-03 0,18115626 ! adaptation of signaling pathway GO:0022401 7 5 0,000 4,568E-03 0,17808582 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 4,568E-03 0,17511772 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 4,568E-03 0,17224694 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 4,568E-03 0,16946876 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 4,568E-03 0,16677878 ! positive regulation of histone modification GO:0031058 5 5 0,000 4,568E-03 0,16417286 ! malate metabolic process GO:0006108 7 5 0,000 4,568E-03 0,16164713 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 4,568E-03 0,15919793 ! behavioral response to pain GO:0048266 7 5 0,000 4,568E-03 0,15682184 ! clathrin coat assembly GO:0048268 11 5 0,000 4,568E-03 0,15451564 ! phototransduction, visible light GO:0007603 6 5 0,000 4,568E-03 0,15227628 ! regulation of dopamine uptake GO:0051584 9 5 0,000 4,568E-03 0,1501009 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 4,568E-03 0,14798681 ! mating behavior GO:0007617 6 5 0,000 4,568E-03 0,14593144 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 4,568E-03 0,14393237 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 4,568E-03 0,14198734 ! rhythmic behavior GO:0007622 12 5 0,000 4,568E-03 0,14009418 ! copulation GO:0007620 7 5 0,000 4,568E-03 0,13825083 ! glial cell fate commitment GO:0021781 12 5 0,000 4,568E-03 0,13645537 ! protein maturation by protein folding GO:0022417 12 5 0,000 4,568E-03 0,13470594 ! embryonic hemopoiesis GO:0035162 10 5 0,000 4,568E-03 0,1330008 ! regulation of potassium ion transport GO:0043266 9 5 0,000 4,568E-03 0,13133829 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 4,568E-03 0,12971683 ! apoptotic cell clearance GO:0043277 13 5 0,000 4,568E-03 0,12813492 ! lipoprotein particle clearance GO:0034381 9 5 0,000 4,568E-03 0,12659112 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 4,568E-03 0,12508409 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 4,568E-03 0,12361251 ! response to protozoan GO:0001562 9 5 0,000 4,568E-03 0,12217516 ! positive regulation of glycolysis GO:0045821 11 5 0,000 4,568E-03 0,12077084 ! lymph vessel development GO:0001945 7 5 0,000 4,568E-03 0,11939845 ! endochondral ossification GO:0001958 12 5 0,000 4,568E-03 0,11805689 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 4,568E-03 0,11674515 ! parathyroid gland development GO:0060017 8 5 0,000 4,568E-03 0,11546223 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 4,568E-03 0,11420721 ! anagen GO:0042640 6 5 0,000 4,568E-03 0,11297918 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 4,568E-03 0,11177727 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 4,568E-03 0,11060067 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 4,568E-03 0,10944858 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 4,568E-03 0,10832024 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 4,568E-03 0,10721493 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 4,568E-03 0,10613195 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 4,568E-03 0,10507063 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 4,568E-03 0,10403033 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 4,568E-03 0,10301042 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 4,568E-03 0,10201032 ! cardiac muscle fiber development GO:0048739 7 5 0,000 4,568E-03 0,10102946 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 4,568E-03 0,10006727 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 4,568E-03 0,09912324 ! neutrophil mediated immunity GO:0002446 6 5 0,000 4,568E-03 0,09819685 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 4,568E-03 0,09728762 ! ovulation GO:0030728 6 5 0,000 4,568E-03 0,09639508 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 4,568E-03 0,09551876 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 4,568E-03 0,09465823 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 4,568E-03 0,09381307 ! response to pH GO:0009268 9 5 0,000 4,568E-03 0,09298286 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 4,568E-03 0,09216722 ! proline biosynthetic process GO:0006561 6 5 0,000 4,568E-03 0,09136577 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 4,568E-03 0,09057813 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 4,568E-03 0,08980396 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 4,568E-03 0,08904291 ! polyol biosynthetic process GO:0046173 5 5 0,000 4,568E-03 0,08829465 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 4,568E-03 0,08755886 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 4,568E-03 0,08683523 ! sister chromatid cohesion GO:0007062 9 5 0,000 4,568E-03 0,08612347 ! nerve growth factor processing GO:0032455 7 5 0,000 4,568E-03 0,08542328 ! urea metabolic process GO:0019627 6 5 0,000 4,568E-03 0,08473438 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 4,568E-03 0,08405651 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 4,568E-03 0,08338939 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 4,568E-03 0,08273278 ! neutrophil activation GO:0042119 5 5 0,000 4,568E-03 0,08208643 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 4,568E-03 0,0814501 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 4,568E-03 0,08082356 ! response to food GO:0032094 5 5 0,000 4,568E-03 0,08020659 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 4,568E-03 0,07959896 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 4,568E-03 0,07900048 ! paraxial mesoderm development GO:0048339 9 5 0,000 4,568E-03 0,07841092 ! forebrain neuron development GO:0021884 7 5 0,000 4,568E-03 0,0778301 ! melanosome organization GO:0032438 7 5 0,000 4,568E-03 0,07725782 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 4,568E-03 0,07669389 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 4,568E-03 0,07613814 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 4,568E-03 0,07559038 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 4,568E-03 0,07505045 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 4,568E-03 0,07451818 ! nucleoside transport GO:0015858 6 5 0,000 4,568E-03 0,0739934 ! nucleoside salvage GO:0043174 7 5 0,000 4,568E-03 0,07347597 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 4,568E-03 0,07296572 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 4,568E-03 0,07246251 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 4,568E-03 0,07196619 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 4,568E-03 0,07147662 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 4,568E-03 0,07099367 ! early endosome to late endosome transport GO:0045022 11 5 0,000 4,568E-03 0,0705172 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 4,568E-03 0,07004709 ! depyrimidination GO:0045008 8 5 0,000 4,568E-03 0,0695832 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 4,568E-03 0,06912542 ! 5S class rRNA transcription GO:0042791 8 5 0,000 4,568E-03 0,06867362 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 4,568E-03 0,06822768 ! regulation of centrosome cycle GO:0046605 7 5 0,000 4,568E-03 0,06778751 ! neuronal ion channel clustering GO:0045161 7 5 0,000 4,568E-03 0,06735297 ! sodium ion homeostasis GO:0055078 6 5 0,000 4,568E-03 0,06692397 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 4,568E-03 0,0665004 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 4,568E-03 0,06608216 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 4,568E-03 0,06566915 ! monocyte differentiation GO:0030224 8 5 0,000 4,568E-03 0,06526126 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 4,568E-03 0,06485842 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 4,568E-03 0,06446051 ! centrosome duplication GO:0051298 5 5 0,000 4,568E-03 0,06406746 ! response to UV-C GO:0010225 6 5 0,000 4,568E-03 0,06367917 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 4,568E-03 0,06329556 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 4,568E-03 0,06291655 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 4,568E-03 0,06254204 ! regulation of dendrite development GO:0050773 12 5 0,000 4,568E-03 0,06217197 ! peptidyl-arginine modification GO:0018195 7 5 0,000 4,568E-03 0,06180625 ! positive regulation of organ growth GO:0046622 6 5 0,000 4,568E-03 0,06144481 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 4,568E-03 0,06108758 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 4,568E-03 0,06073447 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 4,568E-03 0,06038542 ! regulation of dopamine secretion GO:0014059 12 5 0,000 4,568E-03 0,06004036 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 4,568E-03 0,05969922 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 4,568E-03 0,05936194 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 4,568E-03 0,05902845 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 4,568E-03 0,05869868 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 4,568E-03 0,05837257 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 4,568E-03 0,05805007 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 4,568E-03 0,05773112 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 4,568E-03 0,05741565 ! neural tube patterning GO:0021532 6 5 0,000 4,568E-03 0,05710361 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 4,568E-03 0,05679494 ! histone demethylation GO:0016577 9 5 0,000 4,568E-03 0,05648959 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 4,568E-03 0,0561875 ! regulation of sterol transport GO:0032371 7 5 0,000 4,568E-03 0,05588863 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 4,568E-03 0,05559293 ! enteric nervous system development GO:0048484 8 5 0,000 4,568E-03 0,05530033 ! establishment of planar polarity GO:0001736 6 5 0,000 4,568E-03 0,0550108 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 4,568E-03 0,05472429 ! muscle cell proliferation GO:0033002 8 5 0,000 4,568E-03 0,05444074 ! transcription termination GO:0006353 8 5 0,000 4,568E-03 0,05416012 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 4,568E-03 0,05388238 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 4,568E-03 0,05360747 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 4,568E-03 0,05333535 ! regulation of respiratory burst GO:0060263 8 5 0,000 4,568E-03 0,05306598 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 4,568E-03 0,05279931 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 4,568E-03 0,05253532 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 4,568E-03 0,05227395 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 4,568E-03 0,05201517 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 4,568E-03 0,05175893 ! apical protein localization GO:0045176 6 5 0,000 4,568E-03 0,05150521 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 4,568E-03 0,05125397 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 4,568E-03 0,05100516 ! galactolipid metabolic process GO:0019374 7 5 0,000 4,568E-03 0,05075876 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 4,568E-03 0,05051473 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 4,568E-03 0,05027303 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 4,568E-03 0,05003363 ! triglyceride catabolic process GO:0019433 6 5 0,000 4,568E-03 0,04979651 ! glial cell migration GO:0008347 10 5 0,000 4,568E-03 0,04956162 ! determination of adult lifespan GO:0008340 8 5 0,000 4,568E-03 0,04932894 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 4,568E-03 0,04909843 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 4,568E-03 0,04887006 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 4,568E-03 0,04864381 ! somatic stem cell maintenance GO:0035019 13 5 0,000 4,568E-03 0,04841965 ! cerebellar cortex formation GO:0021697 6 5 0,000 4,568E-03 0,04819754 ! neural plate development GO:0001840 6 5 0,000 4,568E-03 0,04797746 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 4,568E-03 0,04775938 ! regulation of sensory perception GO:0051931 6 5 0,000 4,568E-03 0,04754327 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 4,568E-03 0,04732911 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 4,568E-03 0,04711688 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 4,568E-03 0,04690653 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 4,568E-03 0,04669806 ! sensory cilium assembly GO:0035058 6 5 0,000 4,568E-03 0,04649143 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 4,568E-03 0,04628662 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 4,568E-03 0,04608361 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 4,568E-03 0,04588237 ! spindle assembly GO:0051225 5 5 0,000 4,568E-03 0,04568288 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 4,568E-03 0,04548512 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 4,568E-03 0,04528907 ! protein amino acid prenylation GO:0018346 9 5 0,000 4,568E-03 0,04509469 ! organ regeneration GO:0031100 7 5 0,000 4,568E-03 0,04490198 ! NAD biosynthetic process GO:0009435 7 5 0,000 4,568E-03 0,04471091 ! carnitine metabolic process GO:0009437 5 5 0,000 4,568E-03 0,04452145 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 4,568E-03 0,0443336 ! cellular anion homeostasis GO:0030002 6 5 0,000 4,568E-03 0,04414732 GO:0055081|anion homeostasis, ! tRNA transcription GO:0009304 11 6 0,000 5,48E-03 0,05273251 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 5,48E-03 0,05251279 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 5,48E-03 0,05229489 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 5,48E-03 0,0520788 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 5,48E-03 0,05186448 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 5,48E-03 0,05165192 ! regulation of helicase activity GO:0051095 11 6 0,000 5,48E-03 0,0514411 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 5,48E-03 0,05123199 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 5,48E-03 0,05102457 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 5,48E-03 0,05081883 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 5,48E-03 0,05061473 ! positive regulation of axon extension GO:0045773 8 6 0,000 5,48E-03 0,05041228 ! prostate gland development GO:0030850 9 6 0,000 5,48E-03 0,05021143 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 5,48E-03 0,05001218 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 5,48E-03 0,0498145 ! forebrain neuron differentiation GO:0021879 9 6 0,000 5,48E-03 0,04961838 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 5,48E-03 0,0494238 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 5,48E-03 0,04923074 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 5,48E-03 0,04903918 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 5,48E-03 0,0488491 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 5,48E-03 0,0486605 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 5,48E-03 0,04847334 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 5,48E-03 0,04828762 ! neuron adhesion GO:0007158 9 6 0,000 5,48E-03 0,04810332 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 5,48E-03 0,04792041 ! establishment of tissue polarity GO:0007164 7 6 0,000 5,48E-03 0,0477389 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 5,48E-03 0,04755875 ! signal peptide processing GO:0006465 8 6 0,000 5,48E-03 0,04737996 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 5,48E-03 0,0472025 ! mRNA stabilization GO:0048255 15 6 0,000 5,48E-03 0,04702638 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 5,48E-03 0,04685156 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 5,48E-03 0,04667803 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 5,48E-03 0,04650579 ! opsonization GO:0008228 8 6 0,000 5,48E-03 0,04633481 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 5,48E-03 0,04616509 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 5,48E-03 0,0459966 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 5,48E-03 0,04582934 ! protein amino acid dealkylation GO:0008214 11 6 0,000 5,48E-03 0,04566329 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 5,48E-03 0,04549844 ! photoreceptor cell development GO:0042461 10 6 0,000 5,48E-03 0,04533478 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 5,48E-03 0,04517229 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 5,48E-03 0,04501096 ! mechanosensory behavior GO:0007638 8 6 0,000 5,48E-03 0,04485078 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 5,48E-03 0,04469173 ! negative regulation of endocytosis GO:0045806 8 6 0,000 5,48E-03 0,04453381 ! response to interferon-gamma GO:0034341 12 6 0,000 5,48E-03 0,044377 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 5,48E-03 0,04422129 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 5,48E-03 0,04406667 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 5,48E-03 0,04391313 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 5,48E-03 0,04376066 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 5,48E-03 0,04360923 ! cGMP-mediated signaling GO:0019934 10 6 0,000 5,48E-03 0,04345886 ! activation of MAPKKK activity GO:0000185 10 6 0,000 5,48E-03 0,04330951 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 5,48E-03 0,04316119 ! thymic T cell selection GO:0045061 12 6 0,000 5,48E-03 0,04301389 ! protein lipoylation GO:0009249 10 6 0,000 5,48E-03 0,04286758 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 5,48E-03 0,04272227 ! pigment granule organization GO:0048753 11 6 0,000 5,48E-03 0,04257794 ! drug transport GO:0015893 6 6 0,000 5,48E-03 0,04243458 ! cysteine metabolic process GO:0006534 7 6 0,000 5,48E-03 0,04229218 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 5,48E-03 0,04215073 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 5,48E-03 0,04201023 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 5,48E-03 0,04187066 ! histidine metabolic process GO:0006547 6 6 0,000 5,48E-03 0,04173202 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 5,48E-03 0,04159429 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 5,48E-03 0,04145746 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 5,48E-03 0,04132154 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 5,48E-03 0,0411865 ! adenohypophysis development GO:0021984 10 6 0,000 5,48E-03 0,04105234 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 5,48E-03 0,04091905 ! hyperosmotic response GO:0006972 8 6 0,000 5,48E-03 0,04078663 ! microtubule nucleation GO:0007020 10 6 0,000 5,48E-03 0,04065506 ! ER overload response GO:0006983 7 6 0,000 5,48E-03 0,04052434 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 5,48E-03 0,04039445 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 5,48E-03 0,0402654 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 5,48E-03 0,04013716 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 5,48E-03 0,04000974 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 5,48E-03 0,03988313 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 5,48E-03 0,03975731 ! response to dietary excess GO:0002021 7 6 0,000 5,48E-03 0,03963229 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 5,48E-03 0,03950805 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 5,48E-03 0,03938459 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 5,48E-03 0,0392619 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 5,48E-03 0,03913997 ! glycerol ether catabolic process GO:0044269 8 6 0,000 5,48E-03 0,03901879 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 5,48E-03 0,03889836 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 5,48E-03 0,03877867 ! neuron apoptosis GO:0051402 8 6 0,000 5,48E-03 0,03865972 ! organic alcohol transport GO:0015850 9 6 0,000 5,48E-03 0,03854149 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 5,48E-03 0,03842399 ! T cell mediated immunity GO:0002456 12 6 0,000 5,48E-03 0,0383072 ! male sex determination GO:0030238 9 6 0,000 5,48E-03 0,03819112 ! carnitine transport GO:0015879 8 6 0,000 5,48E-03 0,03807574 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 5,48E-03 0,03796105 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 5,48E-03 0,03784705 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 5,48E-03 0,03773374 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 5,48E-03 0,0376211 ! positive regulation of exocytosis GO:0045921 6 6 0,000 5,48E-03 0,03750913 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 5,48E-03 0,03739783 ! parturition GO:0007567 12 6 0,000 5,48E-03 0,03728719 ! negative regulation of translational initiation GO:0045947 7 6 0,000 5,48E-03 0,03717719 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 5,48E-03 0,03706785 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 5,48E-03 0,03695915 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 5,48E-03 0,03685108 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 5,48E-03 0,03674364 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 5,48E-03 0,03663683 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 5,48E-03 0,03653063 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 5,48E-03 0,03642505 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 5,48E-03 0,03632008 ! macrophage differentiation GO:0030225 10 6 0,000 5,48E-03 0,03621571 ! astrocyte development GO:0014002 14 6 0,000 5,48E-03 0,03611194 ! hyaluronan metabolic process GO:0030212 6 6 0,000 5,48E-03 0,03600877 ! purine base biosynthetic process GO:0009113 14 6 0,000 5,48E-03 0,03590618 ! interaction with symbiont GO:0051702 8 6 0,000 5,48E-03 0,03580417 ! anterograde axon cargo transport GO:0008089 8 6 0,000 5,48E-03 0,03570274 ! skeletal muscle contraction GO:0003009 6 6 0,000 5,48E-03 0,03560189 ! eating behavior GO:0042755 6 6 0,000 5,48E-03 0,0355016 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 5,48E-03 0,03540188 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 5,48E-03 0,03530271 ! response to copper ion GO:0046688 9 6 0,000 5,48E-03 0,0352041 ! DNA topological change GO:0006265 8 6 0,000 5,48E-03 0,03510604 ! response to exogenous dsRNA GO:0043330 8 6 0,000 5,48E-03 0,03500852 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 5,48E-03 0,03491155 ! establishment of melanosome localization GO:0032401 9 6 0,000 5,48E-03 0,03481511 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 5,48E-03 0,0347192 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 5,48E-03 0,03462382 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 5,48E-03 0,03452896 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 5,48E-03 0,03443461 ! nucleoside catabolic process GO:0009164 6 6 0,000 5,48E-03 0,03434079 ! gas homeostasis GO:0033483 11 6 0,000 5,48E-03 0,03424747 ! hair follicle maturation GO:0048820 7 6 0,000 5,48E-03 0,03415466 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 5,48E-03 0,03406235 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 5,48E-03 0,03397054 ! Schwann cell development GO:0014044 14 6 0,000 5,48E-03 0,03387922 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 5,48E-03 0,03378839 ! dendrite morphogenesis GO:0048813 9 6 0,000 5,48E-03 0,03369804 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 5,48E-03 0,03360818 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 5,48E-03 0,0335188 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 5,48E-03 0,03342989 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 5,48E-03 0,03334145 ! histone ubiquitination GO:0016574 7 6 0,000 5,48E-03 0,03325348 ! regulation of meiosis GO:0040020 10 6 0,000 5,48E-03 0,03316597 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 5,48E-03 0,03307892 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 5,48E-03 0,03299233 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 5,48E-03 0,03290618 ! regulation of mast cell activation GO:0033003 6 6 0,000 5,48E-03 0,03282049 ! membrane to membrane docking GO:0022614 12 6 0,000 5,48E-03 0,03273524 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 5,48E-03 0,03265044 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 5,48E-03 0,03256607 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 5,48E-03 0,03248214 ! receptor internalization GO:0031623 9 6 0,000 5,48E-03 0,03239863 ! neutrophil homeostasis GO:0001780 6 6 0,000 5,48E-03 0,03231556 ! coenzyme A metabolic process GO:0015936 9 6 0,000 5,48E-03 0,03223291 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 5,48E-03 0,03215069 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 5,48E-03 0,03206888 ! protein deubiquitination GO:0016579 8 6 0,000 5,48E-03 0,03198748 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 5,48E-03 0,0319065 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 5,48E-03 0,03182593 ! peptidyl-histidine modification GO:0018202 9 6 0,000 5,48E-03 0,03174577 ! axonal fasciculation GO:0007413 9 6 0,000 5,48E-03 0,031666 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 5,48E-03 0,03158664 ! thiamin metabolic process GO:0006772 6 6 0,000 5,48E-03 0,03150767 ! midbrain development GO:0030901 6 6 0,000 5,48E-03 0,0314291 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 5,48E-03 0,03135092 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 5,48E-03 0,03127312 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 5,48E-03 0,03119571 ! progesterone metabolic process GO:0042448 8 6 0,000 5,48E-03 0,03111869 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 5,48E-03 0,03104204 ! glycolipid catabolic process GO:0019377 13 6 0,000 5,48E-03 0,03096577 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 5,48E-03 0,03088987 ! positive regulation of glucose import GO:0046326 6 6 0,000 5,48E-03 0,03081435 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 5,48E-03 0,03073919 ! adult feeding behavior GO:0008343 6 6 0,000 5,48E-03 0,0306644 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 5,48E-03 0,03058997 ! blastocyst growth GO:0001832 15 6 0,000 5,48E-03 0,03051591 ! pigment granule transport GO:0051904 12 6 0,000 5,48E-03 0,0304422 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 5,48E-03 0,03036884 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 5,48E-03 0,03029584 ! catecholamine transport GO:0051937 7 6 0,000 5,48E-03 0,03022319 ! organ or tissue specific immune response GO:0002251 7 6 0,000 5,48E-03 0,03015088 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 5,48E-03 0,03007892 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 5,48E-03 0,03000731 ! negative regulation of B cell activation GO:0050869 9 6 0,000 5,48E-03 0,02993603 ! protein prenylation GO:0018342 10 6 0,000 5,48E-03 0,02986509 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 5,48E-03 0,02979449 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 5,48E-03 0,02972422 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 5,48E-03 0,02965428 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 5,48E-03 0,02958467 ! positive regulation of coagulation GO:0050820 11 6 0,000 5,48E-03 0,02951538 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 0,000 6,39E-03 0,03433943 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 6,39E-03 0,03425938 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 6,39E-03 0,03417971 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 6,39E-03 0,03410041 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 6,39E-03 0,03402147 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 6,39E-03 0,0339429 ! synaptonemal complex assembly GO:0007130 10 7 0,000 6,39E-03 0,03386469 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 6,39E-03 0,03378684 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 6,39E-03 0,03370935 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 6,39E-03 0,03363221 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 6,39E-03 0,03355542 ! reproductive behavior GO:0019098 12 7 0,000 6,39E-03 0,03347899 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 6,39E-03 0,0334029 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 6,39E-03 0,03332715 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 6,39E-03 0,03325175 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 6,39E-03 0,03317669 ! oligopeptide transport GO:0006857 11 7 0,000 6,39E-03 0,03310197 ! protein amino acid sulfation GO:0006477 9 7 0,000 6,39E-03 0,03302758 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 6,39E-03 0,03295353 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 6,39E-03 0,03287981 ! RNA methylation GO:0001510 11 7 0,000 6,39E-03 0,03280642 ! pericardium development GO:0060039 8 7 0,000 6,39E-03 0,03273335 ! macrophage chemotaxis GO:0048246 10 7 0,000 6,39E-03 0,03266061 ! fibril organization GO:0043206 13 7 0,000 6,39E-03 0,03258819 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 6,39E-03 0,0325161 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 6,39E-03 0,03244432 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 6,39E-03 0,03237285 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 6,39E-03 0,0323017 ! lipoprotein transport GO:0042953 9 7 0,000 6,39E-03 0,03223087 ! cerebral cortex cell migration GO:0021795 11 7 0,000 6,39E-03 0,03216034 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 6,39E-03 0,03209012 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 6,39E-03 0,03202021 ! estrogen metabolic process GO:0008210 14 7 0,000 6,39E-03 0,0319506 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 6,39E-03 0,03188129 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 6,39E-03 0,03181228 ! chemosensory behavior GO:0007635 9 7 0,000 6,39E-03 0,03174357 ! microtubule bundle formation GO:0001578 8 7 0,000 6,39E-03 0,03167516 ! T-helper 1 type immune response GO:0042088 11 7 0,000 6,39E-03 0,03160704 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 6,39E-03 0,03153922 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 6,39E-03 0,03147168 ! leukocyte degranulation GO:0043299 10 7 0,000 6,39E-03 0,03140443 ! bile acid and bile salt transport GO:0015721 9 7 0,000 6,39E-03 0,03133747 ! reflex GO:0060004 12 7 0,000 6,39E-03 0,0312708 ! positive regulation of isotype switching GO:0045830 15 7 0,000 6,39E-03 0,03120441 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 6,39E-03 0,03113829 ! protein-cofactor linkage GO:0018065 13 7 0,000 6,39E-03 0,03107246 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 6,39E-03 0,03100691 ! glycerolipid catabolic process GO:0046503 9 7 0,000 6,39E-03 0,03094163 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 6,39E-03 0,03087663 ! spinal cord patterning GO:0021511 7 7 0,000 6,39E-03 0,0308119 ! hemoglobin metabolic process GO:0020027 10 7 0,000 6,39E-03 0,03074744 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 6,39E-03 0,03068325 ! adrenal gland development GO:0030325 17 7 0,000 6,39E-03 0,03061932 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 6,39E-03 0,03055567 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 6,39E-03 0,03049227 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 6,39E-03 0,03042914 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 6,39E-03 0,03036627 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 6,39E-03 0,03030366 ! endosome organization GO:0007032 10 7 0,000 6,39E-03 0,03024131 ! thyroid hormone generation GO:0006590 11 7 0,000 6,39E-03 0,03017921 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 6,39E-03 0,03011737 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 6,39E-03 0,03005578 ! regulation of pigmentation during development GO:0048070 15 7 0,000 6,39E-03 0,02999444 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 6,39E-03 0,02993335 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 6,39E-03 0,02987251 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 6,39E-03 0,02981192 ! galactose metabolic process GO:0006012 10 7 0,000 6,39E-03 0,02975157 ! vesicle fusion GO:0006906 15 7 0,000 6,39E-03 0,02969146 ! intracellular pH reduction GO:0051452 10 7 0,000 6,39E-03 0,0296316 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 6,39E-03 0,02957198 ! organ growth GO:0035265 11 7 0,000 6,39E-03 0,0295126 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 6,39E-03 0,02945346 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 6,39E-03 0,02939455 ! Rac protein signal transduction GO:0016601 7 7 0,000 6,39E-03 0,02933588 ! retinol metabolic process GO:0042572 9 7 0,000 6,39E-03 0,02927744 ! behavioral fear response GO:0001662 13 7 0,000 6,39E-03 0,02921923 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 6,39E-03 0,02916126 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 6,39E-03 0,02910352 ! rRNA modification GO:0000154 12 7 0,000 6,39E-03 0,029046 ! protein heterooligomerization GO:0051291 10 7 0,000 6,39E-03 0,02898871 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 6,39E-03 0,02893164 ! response to UV-B GO:0010224 11 7 0,000 6,39E-03 0,0288748 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 6,39E-03 0,02881819 ! protein retention in ER lumen GO:0006621 12 7 0,000 6,39E-03 0,02876179 ! intermediate filament organization GO:0045109 11 7 0,000 6,39E-03 0,02870562 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 6,39E-03 0,02864966 ! cardiac muscle cell development GO:0055013 9 7 0,000 6,39E-03 0,02859392 ! fibrinolysis GO:0042730 9 7 0,000 6,39E-03 0,0285384 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 6,39E-03 0,02848309 ! regulation of circadian rhythm GO:0042752 11 7 0,000 6,39E-03 0,028428 ! B cell lineage commitment GO:0002326 17 7 0,000 6,39E-03 0,02837312 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 6,39E-03 0,02831845 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 6,39E-03 0,02826399 ! response to tropane GO:0014073 13 7 0,000 6,39E-03 0,02820974 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 6,39E-03 0,0281557 ! melanosome localization GO:0032400 10 7 0,000 6,39E-03 0,02810186 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 6,39E-03 0,02804824 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 6,39E-03 0,02799481 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 6,39E-03 0,02794159 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 6,39E-03 0,02788857 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 6,39E-03 0,02783575 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 6,39E-03 0,02778313 ! mast cell activation GO:0045576 9 7 0,000 6,39E-03 0,02773071 ! multicellular organismal aging GO:0010259 11 7 0,000 6,39E-03 0,02767848 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 6,39E-03 0,02762646 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 6,39E-03 0,02757463 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 6,39E-03 0,02752299 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 6,39E-03 0,02747154 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 6,39E-03 0,02742029 ! establishment of nucleus localization GO:0040023 13 7 0,000 6,39E-03 0,02736923 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 6,39E-03 0,02731836 ! T cell lineage commitment GO:0002360 12 7 0,000 6,39E-03 0,02726767 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 6,39E-03 0,02721718 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 6,39E-03 0,02716687 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 6,39E-03 0,02711674 ! regulation of lipid transport GO:0032368 13 7 0,000 6,39E-03 0,02706681 ! response to tumor cell GO:0002347 12 7 0,000 6,39E-03 0,02701705 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 6,39E-03 0,02696748 ! neuroblast proliferation GO:0007405 13 7 0,000 6,39E-03 0,02691809 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 6,39E-03 0,02686888 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 6,39E-03 0,02681985 ! peptidyl-threonine modification GO:0018210 18 7 0,000 6,39E-03 0,02677099 ! diuresis GO:0030146 12 7 0,000 6,39E-03 0,02672232 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 6,39E-03 0,02667382 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 6,39E-03 0,0266255 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 6,39E-03 0,02657735 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 6,39E-03 0,02652938 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 6,39E-03 0,02648158 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 6,39E-03 0,02643395 ! melanin biosynthetic process GO:0042438 8 7 0,000 6,39E-03 0,02638649 ! regulation of synaptogenesis GO:0051963 10 7 0,000 6,39E-03 0,0263392 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 6,39E-03 0,02629208 ! dopamine biosynthetic process GO:0042416 15 7 0,000 6,39E-03 0,02624513 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 6,39E-03 0,02619835 ! lymph node development GO:0048535 9 7 0,000 6,39E-03 0,02615174 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 6,39E-03 0,02610528 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 6,39E-03 0,026059 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 6,39E-03 0,02601288 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 6,39E-03 0,02596692 ! endosome to lysosome transport GO:0008333 10 7 0,000 6,39E-03 0,02592112 ! ATP catabolic process GO:0006200 10 7 0,000 6,39E-03 0,02587548 ! establishment of pigment granule localization GO:0051905 13 7 0,000 6,39E-03 0,02583001 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 6,39E-03 0,02578469 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 6,39E-03 0,02573954 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 6,39E-03 0,02569454 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 6,39E-03 0,02564969 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 6,39E-03 0,02560501 ! muscle adaptation GO:0043500 12 7 0,000 6,39E-03 0,02556048 ! amino sugar catabolic process GO:0046348 9 7 0,000 6,39E-03 0,0255161 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 6,39E-03 0,02547188 ! retina homeostasis GO:0001895 9 7 0,000 6,39E-03 0,02542781 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 6,39E-03 0,02538389 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 6,39E-03 0,02534013 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 6,39E-03 0,02529651 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 6,39E-03 0,02525305 ! behavioral response to nicotine GO:0035095 11 7 0,000 6,39E-03 0,02520973 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 6,39E-03 0,02516657 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 6,39E-03 0,02512355 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 7,3E-03 0,02865134 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 7,3E-03 0,02860253 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 7,3E-03 0,02855388 ! axon extension GO:0048675 11 8 0,000 7,3E-03 0,02850541 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 7,3E-03 0,02845709 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 7,3E-03 0,02840894 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 7,3E-03 0,02836095 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 7,3E-03 0,02831313 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 7,3E-03 0,02826546 ! cell proliferation in forebrain GO:0021846 10 8 0,000 7,3E-03 0,02821796 ! positive regulation of B cell proliferation GO:0030890 11 8 0,000 7,3E-03 0,02817061 ! phosphate transport GO:0006817 10 8 0,000 7,3E-03 0,02812342 ! N-glycan processing GO:0006491 12 8 0,000 7,3E-03 0,02807639 ! Golgi to endosome transport GO:0006895 16 8 0,000 7,3E-03 0,02802952 ! UTP metabolic process GO:0046051 8 8 0,000 7,3E-03 0,02798281 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 7,3E-03 0,02793625 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 7,3E-03 0,02788984 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 7,3E-03 0,02784359 ! neurotransmitter uptake GO:0001504 10 8 0,000 7,3E-03 0,02779749 ! succinate metabolic process GO:0006105 14 8 0,000 7,3E-03 0,02775154 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 7,3E-03 0,02770575 ! smoothened signaling pathway GO:0007224 8 8 0,000 7,3E-03 0,02766011 ! membrane hyperpolarization GO:0060081 10 8 0,000 7,3E-03 0,02761461 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 7,3E-03 0,02756927 ! keratinocyte proliferation GO:0043616 12 8 0,000 7,3E-03 0,02752407 ! middle ear morphogenesis GO:0042474 9 8 0,000 7,3E-03 0,02747902 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 7,3E-03 0,02743412 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 7,3E-03 0,02738937 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 7,3E-03 0,02734476 ! ganglioside metabolic process GO:0001573 15 8 0,000 7,3E-03 0,0273003 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 7,3E-03 0,02725598 ! pseudouridine synthesis GO:0001522 9 8 0,000 7,3E-03 0,02721181 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 7,3E-03 0,02716777 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 7,3E-03 0,02712388 ! endothelial cell differentiation GO:0045446 14 8 0,000 7,3E-03 0,02708014 ! ceramide biosynthetic process GO:0046513 9 8 0,000 7,3E-03 0,02703653 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 7,3E-03 0,02699306 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 0,000 7,3E-03 0,02694973 ! astrocyte differentiation GO:0048708 16 8 0,000 7,3E-03 0,02690654 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 7,3E-03 0,02686349 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 7,3E-03 0,02682058 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 7,3E-03 0,02677781 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 7,3E-03 0,02673517 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 7,3E-03 0,02669266 ! melanin metabolic process GO:0006582 12 8 0,000 7,3E-03 0,02665029 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 7,3E-03 0,02660806 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 7,3E-03 0,02656596 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 7,3E-03 0,02652399 ! macrophage activation GO:0042116 12 8 0,000 7,3E-03 0,02648215 ! regulation of type I interferon production GO:0032479 8 8 0,000 7,3E-03 0,02644045 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 7,3E-03 0,02639887 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 7,3E-03 0,02635743 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 7,3E-03 0,02631612 ! regulation of vascular permeability GO:0043114 12 8 0,000 7,3E-03 0,02627494 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 7,3E-03 0,02623388 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 7,3E-03 0,02619295 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 7,3E-03 0,02615216 ! ruffle organization GO:0031529 11 8 0,000 7,3E-03 0,02611148 ! osteoblast development GO:0002076 13 8 0,000 7,3E-03 0,02607094 ! lens development in camera-type eye GO:0002088 10 8 0,000 7,3E-03 0,02603052 ! positive regulation of vasodilation GO:0045909 12 8 0,000 7,3E-03 0,02599022 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 7,3E-03 0,02595005 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 7,3E-03 0,02591001 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 7,3E-03 0,02587008 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 7,3E-03 0,02583028 ! Schwann cell differentiation GO:0014037 17 8 0,000 7,3E-03 0,02579061 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 7,3E-03 0,02575105 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 7,3E-03 0,02571161 ! regulation of gliogenesis GO:0014013 20 8 0,000 7,3E-03 0,0256723 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 7,3E-03 0,02563311 ! oligodendrocyte development GO:0014003 8 8 0,000 7,3E-03 0,02559403 ! segment specification GO:0007379 10 8 0,000 7,3E-03 0,02555507 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 7,3E-03 0,02551624 ! cellular extravasation GO:0045123 11 8 0,000 7,3E-03 0,02547752 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 7,3E-03 0,02543892 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 7,3E-03 0,02540043 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 7,3E-03 0,02536206 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 7,3E-03 0,02532381 ! snRNA metabolic process GO:0016073 10 8 0,000 7,3E-03 0,02528567 GO:0016180|snRNA processing, ! phosphoinositide 3-kinase cascade GO:0014065 23 8 0,000 7,3E-03 0,02524765 ! regulation of interleukin-4 production GO:0032673 16 8 0,000 7,3E-03 0,02520974 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 7,3E-03 0,02517194 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 7,3E-03 0,02513426 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 7,3E-03 0,02509669 ! nucleosome disassembly GO:0006337 12 8 0,000 7,3E-03 0,02505923 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 7,3E-03 0,02502188 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 7,3E-03 0,02498465 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 7,3E-03 0,02494752 ! icosanoid secretion GO:0032309 12 8 0,000 7,3E-03 0,02491051 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 7,3E-03 0,02487361 ! leukocyte activation during immune response GO:0002366 13 8 0,000 7,3E-03 0,02483681 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 7,3E-03 0,02480012 ! cerebellum morphogenesis GO:0021587 9 8 0,000 7,3E-03 0,02476355 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 7,3E-03 0,02472708 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 7,3E-03 0,02469071 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 7,3E-03 0,02465446 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 7,3E-03 0,0246183 ! sterol catabolic process GO:0016127 9 8 0,000 7,3E-03 0,02458226 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 7,3E-03 0,02454632 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 7,3E-03 0,02451049 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 7,3E-03 0,02447476 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 7,3E-03 0,02443913 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 7,3E-03 0,02440361 ! prophase GO:0051324 11 8 0,000 7,3E-03 0,02436819 ! S phase GO:0051320 8 8 0,000 7,3E-03 0,02433288 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 7,3E-03 0,02429766 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 7,3E-03 0,02426255 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 7,3E-03 0,02422754 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 7,3E-03 0,02419263 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 7,3E-03 0,02415782 ! hormone catabolic process GO:0042447 13 8 0,000 7,3E-03 0,02412311 ! quaternary ammonium group transport GO:0015697 10 8 0,000 7,3E-03 0,0240885 ! myeloid cell homeostasis GO:0002262 8 8 0,000 7,3E-03 0,02405399 ! regulation of fibrinolysis GO:0051917 13 8 0,000 7,3E-03 0,02401958 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 7,3E-03 0,02398526 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 7,3E-03 0,02395105 ! regulation of telomere maintenance GO:0032204 10 8 0,000 7,3E-03 0,02391693 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 7,3E-03 0,02388291 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 7,3E-03 0,02384898 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 7,3E-03 0,02381515 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 7,3E-03 0,02378142 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 7,3E-03 0,02374778 ! lamellipodium assembly GO:0030032 9 8 0,000 7,3E-03 0,02371424 ! regulation of embryonic development GO:0045995 16 8 0,000 7,3E-03 0,0236808 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 7,3E-03 0,02364744 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 7,3E-03 0,02361418 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 7,3E-03 0,02358102 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 8,209E-03 0,02648008 ! regulation of developmental growth GO:0048638 13 9 0,000 8,209E-03 0,02644299 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 8,209E-03 0,02640601 ! telencephalon cell migration GO:0022029 16 9 0,000 8,209E-03 0,02636913 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 8,209E-03 0,02633235 ! pentose-phosphate shunt GO:0006098 12 9 0,000 8,209E-03 0,02629568 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 8,209E-03 0,02625911 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 8,209E-03 0,02622263 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 8,209E-03 0,02618626 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 8,209E-03 0,02615 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 8,209E-03 0,02611383 ! GTP metabolic process GO:0046039 9 9 0,000 8,209E-03 0,02607776 ! elastic fiber assembly GO:0048251 13 9 0,000 8,209E-03 0,02604179 ! social behavior GO:0035176 14 9 0,000 8,209E-03 0,02600592 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 8,209E-03 0,02597015 ! artery development GO:0060840 19 9 0,000 8,209E-03 0,02593447 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 8,209E-03 0,0258989 ! regulation of glycolysis GO:0006110 15 9 0,000 8,209E-03 0,02586342 ! response to pain GO:0048265 16 9 0,000 8,209E-03 0,02582804 ! protein complex disassembly GO:0043241 17 9 0,000 8,209E-03 0,02579275 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 8,209E-03 0,02575757 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 8,209E-03 0,02572247 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 8,209E-03 0,02568748 ! lung alveolus development GO:0048286 17 9 0,000 8,209E-03 0,02565258 ! ciliary or flagellar motility GO:0001539 10 9 0,000 8,209E-03 0,02561777 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 8,209E-03 0,02558306 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 8,209E-03 0,02554844 ! regulation of exit from mitosis GO:0007096 12 9 0,000 8,209E-03 0,02551391 ! ventral spinal cord development GO:0021517 11 9 0,000 8,209E-03 0,02547948 ! protein targeting to ER GO:0045047 19 9 0,000 8,209E-03 0,02544514 ! T cell selection GO:0045058 18 9 0,000 8,209E-03 0,0254109 ! endoderm development GO:0007492 12 9 0,000 8,209E-03 0,02537674 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 8,209E-03 0,02534268 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 8,209E-03 0,02530871 ! arginine catabolic process GO:0006527 10 9 0,000 8,209E-03 0,02527483 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 8,209E-03 0,02524104 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 8,209E-03 0,02520734 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 8,209E-03 0,02517373 ! phosphagen metabolic process GO:0006599 12 9 0,000 8,209E-03 0,02514021 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 8,209E-03 0,02510678 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 8,209E-03 0,02507344 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 8,209E-03 0,02504018 ! regulation of stress fiber formation GO:0051492 20 9 0,000 8,209E-03 0,02500702 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 8,209E-03 0,02497394 ! mannose metabolic process GO:0006013 9 9 0,000 8,209E-03 0,02494095 ! receptor clustering GO:0043113 15 9 0,000 8,209E-03 0,02490804 ! epithelial cell development GO:0002064 10 9 0,000 8,209E-03 0,02487523 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 8,209E-03 0,0248425 ! retinoic acid metabolic process GO:0042573 11 9 0,000 8,209E-03 0,02480985 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 8,209E-03 0,02477729 ! positive regulation of translational initiation GO:0045948 10 9 0,000 8,209E-03 0,02474482 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 8,209E-03 0,02471243 ! motor axon guidance GO:0008045 14 9 0,000 8,209E-03 0,02468013 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 8,209E-03 0,02464791 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 8,209E-03 0,02461577 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 8,209E-03 0,02458372 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 8,209E-03 0,02455175 ! blastoderm segmentation GO:0007350 11 9 0,000 8,209E-03 0,02451987 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 8,209E-03 0,02448806 ! DNA ligation GO:0006266 14 9 0,000 8,209E-03 0,02445634 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 8,209E-03 0,0244247 ! response to amine stimulus GO:0014075 13 9 0,000 8,209E-03 0,02439315 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 8,209E-03 0,02436167 ! erythrocyte development GO:0048821 11 9 0,000 8,209E-03 0,02433028 ! renal water homeostasis GO:0003091 14 9 0,000 8,209E-03 0,02429897 ! postreplication repair GO:0006301 11 9 0,000 8,209E-03 0,02426773 ! mRNA cleavage GO:0006379 13 9 0,000 8,209E-03 0,02423658 ! hindbrain morphogenesis GO:0021575 12 9 0,000 8,209E-03 0,02420551 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 8,209E-03 0,02417452 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 8,209E-03 0,0241436 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 8,209E-03 0,02411277 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 8,209E-03 0,02408201 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 8,209E-03 0,02405133 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 8,209E-03 0,02402073 ! acid secretion GO:0046717 14 9 0,000 8,209E-03 0,02399021 ! musculoskeletal movement GO:0050881 11 9 0,000 8,209E-03 0,02395977 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 8,209E-03 0,0239294 ! methionine biosynthetic process GO:0009086 10 9 0,000 8,209E-03 0,02389911 ! purine base metabolic process GO:0006144 18 9 0,000 8,209E-03 0,0238689 ! oocyte differentiation GO:0009994 12 9 0,000 8,209E-03 0,02383876 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 8,209E-03 0,0238087 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 8,209E-03 0,02377871 ! spleen development GO:0048536 15 9 0,000 8,209E-03 0,0237488 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 8,209E-03 0,02371897 ! anterior/posterior axis specification GO:0009948 11 9 0,000 8,209E-03 0,02368921 ! regulation of RNA splicing GO:0043484 14 9 0,000 8,209E-03 0,02365952 ! detection of calcium ion GO:0005513 13 9 0,000 8,209E-03 0,02362991 ! blastocyst formation GO:0001825 12 9 0,000 8,209E-03 0,02360037 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 8,209E-03 0,02357091 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 8,209E-03 0,02354152 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 8,209E-03 0,0235122 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 8,209E-03 0,02348296 ! regulation of amino acid transport GO:0051955 11 9 0,000 8,209E-03 0,02345378 ! positive regulation of amine transport GO:0051954 15 9 0,000 8,209E-03 0,02342469 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 8,209E-03 0,02339566 ! prepulse inhibition GO:0060134 14 9 0,000 8,209E-03 0,0233667 ! embryonic placenta development GO:0001892 12 9 0,000 8,209E-03 0,02333782 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 8,209E-03 0,02330901 ! insulin secretion GO:0030073 17 9 0,000 8,209E-03 0,02328027 ! sequestering of metal ion GO:0051238 11 9 0,000 8,209E-03 0,0232516 ! response to nicotine GO:0035094 16 9 0,000 8,209E-03 0,023223 ! establishment of cell polarity GO:0030010 12 9 0,000 8,209E-03 0,02319447 ! nucleus localization GO:0051647 15 9 0,000 8,209E-03 0,02316601 ! regulation of synapse organization GO:0050807 12 9 0,000 8,209E-03 0,02313762 ! localization within membrane GO:0051668 15 9 0,000 8,209E-03 0,0231093 ! negative regulation of muscle development GO:0048635 12 10 0,000 9,117E-03 0,02563461 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 9,117E-03 0,02560331 ! neuron fate specification GO:0048665 11 10 0,000 9,117E-03 0,02557209 ! negative regulation of blood pressure GO:0045776 22 10 0,000 9,117E-03 0,02554094 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 9,117E-03 0,02550987 ! thyroid gland development GO:0030878 19 10 0,000 9,117E-03 0,02547888 ! regulation of B cell proliferation GO:0030888 15 10 0,000 9,117E-03 0,02544795 ! regulation of phosphatase activity GO:0010921 21 10 0,000 9,117E-03 0,02541711 ! synapsis GO:0007129 13 10 0,000 9,117E-03 0,02538634 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 9,117E-03 0,02535564 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 9,117E-03 0,02532502 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 9,117E-03 0,02529447 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 9,117E-03 0,02526399 ! sulfate transport GO:0008272 12 10 0,000 9,117E-03 0,02523359 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 9,117E-03 0,02520326 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 9,117E-03 0,02517301 ! androgen metabolic process GO:0008209 13 10 0,000 9,117E-03 0,02514282 ! phospholipid efflux GO:0033700 16 10 0,000 9,117E-03 0,02511271 ! hippocampus development GO:0021766 19 10 0,000 9,117E-03 0,02508267 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 9,117E-03 0,02505271 ! blood vessel remodeling GO:0001974 21 10 0,000 9,117E-03 0,02502281 ! positive regulation of heart contraction GO:0045823 14 10 0,000 9,117E-03 0,02499299 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 9,117E-03 0,02496323 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 9,117E-03 0,02493355 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 9,117E-03 0,02490394 ! pathogenesis GO:0009405 13 10 0,000 9,117E-03 0,02487439 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 9,117E-03 0,02484492 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 9,117E-03 0,02481552 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 9,117E-03 0,02478619 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 9,117E-03 0,02475692 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 9,117E-03 0,02472773 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 9,117E-03 0,0246986 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 9,117E-03 0,02466955 ! melanocyte differentiation GO:0030318 15 10 0,000 9,117E-03 0,02464056 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 9,117E-03 0,02461164 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 9,117E-03 0,02458278 ! reverse cholesterol transport GO:0043691 16 10 0,000 9,117E-03 0,024554 ! response to X-ray GO:0010165 16 10 0,000 9,117E-03 0,02452528 ! B cell proliferation GO:0042100 14 10 0,000 9,117E-03 0,02449663 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 9,117E-03 0,02446804 ! regulation of sodium ion transport GO:0002028 15 10 0,000 9,117E-03 0,02443953 ! forebrain cell migration GO:0021885 17 10 0,000 9,117E-03 0,02441108 ! lipid digestion GO:0044241 15 10 0,000 9,117E-03 0,02438269 ! phagocytosis, engulfment GO:0006911 20 10 0,000 9,117E-03 0,02435437 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 9,117E-03 0,02432612 ! UV protection GO:0009650 14 10 0,000 9,117E-03 0,02429793 ! entry into host cell GO:0030260 20 10 0,000 9,117E-03 0,02426981 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 9,117E-03 0,02424175 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 9,117E-03 0,02421376 ! negative regulation of ossification GO:0030279 19 10 0,000 9,117E-03 0,02418583 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 9,117E-03 0,02415797 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 9,117E-03 0,02413017 ! regulation of bone resorption GO:0045124 24 10 0,000 9,117E-03 0,02410243 ! alpha-beta T cell activation GO:0046631 16 10 0,000 9,117E-03 0,02407476 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 9,117E-03 0,02404715 ! regulation of organ growth GO:0046620 11 10 0,000 9,117E-03 0,0240196 ! response to dsRNA GO:0043331 18 10 0,000 9,117E-03 0,02399212 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 9,117E-03 0,0239647 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 9,117E-03 0,02393735 ! embryonic axis specification GO:0000578 12 10 0,000 9,117E-03 0,02391005 ! regulation of B cell differentiation GO:0045577 16 10 0,000 9,117E-03 0,02388282 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 9,117E-03 0,02385565 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 9,117E-03 0,02382854 ! cranial nerve development GO:0021545 12 10 0,000 9,117E-03 0,02380149 ! fucose catabolic process GO:0019317 16 10 0,000 9,117E-03 0,02377451 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 9,117E-03 0,02374758 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 9,117E-03 0,02372072 ! protein sumoylation GO:0016925 12 10 0,000 9,117E-03 0,02369391 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 9,117E-03 0,02366717 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 9,117E-03 0,02364049 ! zymogen activation GO:0031638 14 10 0,000 9,117E-03 0,02361387 ! salivary gland development GO:0007431 22 10 0,000 9,117E-03 0,02358731 ! negative regulation of neurological system process GO:0031645 19 10 0,000 9,117E-03 0,0235608 ! glutathione biosynthetic process GO:0006750 11 10 0,000 9,117E-03 0,02353436 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 9,117E-03 0,02350798 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 9,117E-03 0,02348165 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 9,117E-03 0,02345539 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 9,117E-03 0,02342918 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 9,117E-03 0,02340303 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 9,117E-03 0,02337694 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 9,117E-03 0,02335091 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 9,117E-03 0,02332493 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 9,117E-03 0,02329902 ! detection of bacterium GO:0016045 10 10 0,000 9,117E-03 0,02327316 ! embryonic gut development GO:0048566 11 10 0,000 9,117E-03 0,02324736 ! activation of innate immune response GO:0002218 10 10 0,000 9,117E-03 0,02322161 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 9,117E-03 0,02319592 ! cardiac cell differentiation GO:0035051 16 10 0,000 9,117E-03 0,02317029 ! developmental induction GO:0031128 13 10 0,000 9,117E-03 0,02314472 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 9,117E-03 0,0231192 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 9,117E-03 0,02309374 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 9,117E-03 0,02306833 ! negative regulation of immune effector process GO:0002698 16 10 0,000 9,117E-03 0,02304298 ! rRNA transcription GO:0009303 17 11 0,000 0,01002441 0,0253086 ! respiratory burst GO:0045730 14 11 0,000 0,01002441 0,02528085 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,01002441 0,02525316 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,01002441 0,02522554 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,01002441 0,02519797 ! virus-host interaction GO:0019048 17 11 0,000 0,01002441 0,02517046 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 0,01002441 0,02514301 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,01002441 0,02511562 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,01002441 0,02508829 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,01002441 0,02506102 ! RNA polyadenylation GO:0043631 19 11 0,000 0,01002441 0,02503381 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,01002441 0,02500666 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,01002441 0,02497957 ! mating GO:0007618 14 11 0,000 0,01002441 0,02495253 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,01002441 0,02492556 ! T cell proliferation GO:0042098 20 11 0,000 0,01002441 0,02489864 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,01002441 0,02487178 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,01002441 0,02484498 ! bone resorption GO:0045453 16 11 0,000 0,01002441 0,02481823 ! regulated secretory pathway GO:0045055 14 11 0,000 0,01002441 0,02479155 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,01002441 0,02476492 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,01002441 0,02473835 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,01002441 0,02471183 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,01002441 0,02468537 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,01002441 0,02465897 ! syncytium formation GO:0006949 15 11 0,000 0,01002441 0,02463263 ! plasma membrane organization GO:0007009 18 11 0,000 0,01002441 0,02460634 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,01002441 0,02458011 ! focal adhesion formation GO:0048041 24 11 0,000 0,01002441 0,02455393 ! mitotic spindle organization GO:0007052 15 11 0,000 0,01002441 0,02452781 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,01002441 0,02450174 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,01002441 0,02447573 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,01002441 0,02444978 ! adult heart development GO:0007512 11 11 0,000 0,01002441 0,02442388 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,01002441 0,02439803 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,01002441 0,02437224 ! temperature homeostasis GO:0001659 16 11 0,000 0,01002441 0,0243465 ! L-glutamate transport GO:0015813 16 11 0,000 0,01002441 0,02432082 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,01002441 0,02429519 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,01002441 0,02426962 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,01002441 0,0242441 ! stem cell development GO:0048864 29 11 0,000 0,01002441 0,02421863 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,01002441 0,02419322 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,01002441 0,02416786 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,01002441 0,02414255 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,01002441 0,0241173 ! vasoconstriction GO:0042310 15 11 0,000 0,01002441 0,0240921 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,01002441 0,02406695 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,01002441 0,02404186 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,01002441 0,02401681 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,01002441 0,02399182 ! ribosome assembly GO:0042255 13 11 0,000 0,01002441 0,02396688 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,01002441 0,02394199 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,01002441 0,02391716 ! chromatin silencing GO:0006342 19 11 0,000 0,01002441 0,02389237 ! nucleosome positioning GO:0016584 13 11 0,000 0,01002441 0,02386764 ! T cell homeostasis GO:0043029 20 11 0,000 0,01002441 0,02384296 ! regulation of isotype switching GO:0045191 19 11 0,000 0,01002441 0,02381833 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,01002441 0,02379375 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,01002441 0,02376922 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,01002441 0,02374474 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,01002441 0,02372031 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,01002441 0,02369593 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,01002441 0,0236716 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,01002441 0,02364732 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,01002441 0,02362309 ! male genitalia development GO:0030539 13 11 0,000 0,01002441 0,02359891 ! cholesterol efflux GO:0033344 19 11 0,000 0,01002441 0,02357478 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,01002441 0,0235507 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,01002441 0,02352667 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,01002441 0,02350269 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,01002441 0,02347876 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,01002441 0,02345487 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,01002441 0,02343104 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,01002441 0,02340725 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,01002441 0,02338351 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,01002441 0,02335982 ! lysogeny GO:0030069 18 11 0,000 0,01002441 0,02333617 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,01002441 0,02331258 ! acrosome reaction GO:0007340 13 11 0,000 0,01002441 0,02328903 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,01002441 0,02326553 ! lactation GO:0007595 20 12 0,000 0,01093103 0,02534412 ! reproductive cellular process GO:0048610 14 12 0,000 0,01093103 0,0253186 ! tRNA modification GO:0006400 14 12 0,000 0,01093103 0,02529313 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,01093103 0,02526771 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,01093103 0,02524234 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,01093103 0,02521702 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,01093103 0,02519176 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,01093103 0,02516654 ! non-recombinational repair GO:0000726 19 12 0,000 0,01093103 0,02514137 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,01093103 0,02511626 ! peroxisomal transport GO:0043574 21 12 0,000 0,01093103 0,02509119 ! cartilage condensation GO:0001502 18 12 0,000 0,01093103 0,02506617 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,01093103 0,02504121 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,01093103 0,02501629 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,01093103 0,02499142 ! heart looping GO:0001947 15 12 0,000 0,01093103 0,02496661 ! palate development GO:0060021 15 12 0,000 0,01093103 0,02494184 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,01093103 0,02491712 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,01093103 0,02489245 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,01093103 0,02486783 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,01093103 0,02484325 ! arginine metabolic process GO:0006525 13 12 0,000 0,01093103 0,02481873 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,01093103 0,02479425 ! methionine metabolic process GO:0006555 13 12 0,000 0,01093103 0,02476982 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,01093103 0,02474544 ! Golgi organization GO:0007030 18 12 0,000 0,01093103 0,02472111 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,01093103 0,02469683 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,01093103 0,02467259 ! monoamine transport GO:0015844 13 12 0,000 0,01093103 0,0246484 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01093103 0,02462426 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,01093103 0,02460017 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,01093103 0,02457612 ! L-amino acid transport GO:0015807 20 12 0,000 0,01093103 0,02455212 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,01093103 0,02452817 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,01093103 0,02450426 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,01093103 0,0244804 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,01093103 0,02445659 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,01093103 0,02443282 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,01093103 0,0244091 ! cerebellum development GO:0021549 13 12 0,000 0,01093103 0,02438542 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,01093103 0,02436179 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,01093103 0,02433821 ! histone acetylation GO:0016573 23 12 0,000 0,01093103 0,02431467 ! histone methylation GO:0016571 15 12 0,000 0,01093103 0,02429118 ! autonomic nervous system development GO:0048483 23 12 0,000 0,01093103 0,02426773 ! gland morphogenesis GO:0022612 23 12 0,000 0,01093103 0,02424433 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,01093103 0,02422097 ! peptidyl-lysine modification GO:0018205 18 12 0,000 0,01093103 0,02419766 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,01093103 0,0241744 ! response to gamma radiation GO:0010332 20 12 0,000 0,01093103 0,02415117 ! regulation of epidermis development GO:0045682 17 12 0,000 0,01093103 0,024128 ! intestinal absorption GO:0050892 19 12 0,000 0,01093103 0,02410486 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,01093103 0,02408177 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,01093103 0,02405873 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,01093103 0,02403573 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,01093103 0,02401277 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,01093103 0,02398986 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,01093103 0,02396699 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,01093103 0,02394416 ! microspike assembly GO:0030035 23 12 0,000 0,01093103 0,02392138 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,01093103 0,02389864 ! response to cold GO:0009409 14 12 0,000 0,01093103 0,02387595 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 0,01183688 0,02582999 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,01183688 0,02580551 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,01183688 0,02578107 ! cGMP metabolic process GO:0046068 16 13 0,000 0,01183688 0,02575668 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,01183688 0,02573234 ! water transport GO:0006833 17 13 0,000 0,01183688 0,02570804 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,01183688 0,02568379 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,01183688 0,02565958 ! lipid localization GO:0010876 24 13 0,000 0,01183688 0,02563542 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,01183688 0,0256113 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,01183688 0,02558723 ! organelle fusion GO:0048284 28 13 0,000 0,01183688 0,02556321 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,01183688 0,02553923 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,01183688 0,02551529 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,01183688 0,0254914 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,01183688 0,02546755 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,01183688 0,02544375 ! response to hexose stimulus GO:0009746 19 13 0,000 0,01183688 0,02541999 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! glutamate metabolic process GO:0006536 18 13 0,000 0,01183688 0,02539628 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,01183688 0,02537261 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,01183688 0,02534899 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,01183688 0,02532541 ! NAD metabolic process GO:0019674 21 13 0,000 0,01183688 0,02530187 ! exocrine system development GO:0035272 27 13 0,000 0,01183688 0,02527838 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,01183688 0,02525493 ! bone mineralization GO:0030282 15 13 0,000 0,01183688 0,02523152 ! regulation of exocytosis GO:0017157 17 13 0,000 0,01183688 0,02520816 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,01183688 0,02518484 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,01183688 0,02516157 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,01183688 0,02513833 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,01183688 0,02511514 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,01183688 0,02509199 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,01183688 0,02506889 ! genitalia development GO:0048806 15 13 0,000 0,01183688 0,02504583 ! regulation of cellular pH GO:0030641 20 13 0,000 0,01183688 0,02502281 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 0,01183688 0,02499983 ! cellular pigmentation GO:0033059 24 13 0,000 0,01183688 0,02497689 ! tissue regeneration GO:0042246 21 13 0,000 0,01183688 0,024954 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,01183688 0,02493115 ! cofactor transport GO:0051181 19 13 0,000 0,01183688 0,02490834 ! NADP metabolic process GO:0006739 18 13 0,000 0,01183688 0,02488557 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,01183688 0,02486284 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,01183688 0,02484016 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,01183688 0,02481752 ! gas transport GO:0015669 18 13 0,000 0,01183688 0,02479491 ! regulation of RNA stability GO:0043487 28 13 0,000 0,01183688 0,02477235 ! heme biosynthetic process GO:0006783 20 13 0,000 0,01183688 0,02474983 ! regulation of axon extension GO:0030516 23 13 0,000 0,01183688 0,02472735 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,01183688 0,02470491 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,01183688 0,02468252 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,01183688 0,02466016 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,01183688 0,02463784 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,01183688 0,02461556 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,01183688 0,02459333 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,01274194 0,02644988 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,01274194 0,02642603 ! superoxide anion generation GO:0042554 18 14 0,000 0,01274194 0,02640222 ! neuron maturation GO:0042551 21 14 0,000 0,01274194 0,02637846 ! regulation of S phase GO:0033261 18 14 0,000 0,01274194 0,02635474 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,01274194 0,02633106 ! myotube differentiation GO:0014902 21 14 0,000 0,01274194 0,02630742 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 0,01274194 0,02628383 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,01274194 0,02626028 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,01274194 0,02623677 ! inositol metabolic process GO:0006020 20 14 0,000 0,01274194 0,0262133 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,01274194 0,02618987 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,01274194 0,02616649 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,01274194 0,02614315 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,01274194 0,02611985 ! gene silencing by RNA GO:0031047 20 14 0,000 0,01274194 0,02609659 ! response to cAMP GO:0051591 19 14 0,000 0,01274194 0,02607337 ! limbic system development GO:0021761 25 14 0,000 0,01274194 0,02605019 ! startle response GO:0001964 21 14 0,000 0,01274194 0,02602706 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,01274194 0,02600396 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,01274194 0,02598091 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,01274194 0,0259579 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,01274194 0,02593493 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,01274194 0,025912 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,01274194 0,02588911 ! glycine metabolic process GO:0006544 22 14 0,000 0,01274194 0,02586626 ! pituitary gland development GO:0021983 23 14 0,000 0,01274194 0,02584345 ! cellular response to starvation GO:0009267 21 14 0,000 0,01274194 0,02582068 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,01274194 0,02579795 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,01274194 0,02577526 ! regulation of heart rate GO:0002027 23 14 0,000 0,01274194 0,02575261 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,01274194 0,02573 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,01274194 0,02570743 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,01274194 0,0256849 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,01274194 0,02566241 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,01274194 0,02563995 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,01274194 0,02561754 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,01274194 0,02559517 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,01274194 0,02557283 ! axon cargo transport GO:0008088 27 14 0,000 0,01274194 0,02555054 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,01274194 0,02552828 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,01274194 0,02550606 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,01274194 0,02548388 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,01274194 0,02546174 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,01274194 0,02543964 ! mRNA splice site selection GO:0006376 26 14 0,000 0,01274194 0,02541758 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,01274194 0,02539555 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,01274194 0,02537357 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,01274194 0,02535162 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,01274194 0,0253297 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,01274194 0,02530783 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,01274194 0,02528599 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,01274194 0,0252642 ! muscle maintenance GO:0046716 19 14 0,000 0,01274194 0,02524244 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,01274194 0,02522071 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,01274194 0,02519903 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,01274194 0,02517738 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,01274194 0,02515577 ! cell killing GO:0001906 20 14 0,000 0,01274194 0,02513419 ! release of cytochrome c from mitochondria GO:0001836 23 14 0,000 0,01274194 0,02511265 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,01274194 0,02509115 ! cilium assembly GO:0042384 20 14 0,000 0,01274194 0,02506969 ! peptide hormone secretion GO:0030072 23 14 0,000 0,01274194 0,02504826 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,01364623 0,02680302 ! positive regulation of cell size GO:0045793 20 15 0,000 0,01364623 0,02678015 ! metencephalon development GO:0022037 19 15 0,000 0,01364623 0,02675732 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,01364623 0,02673453 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,01364623 0,02671177 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,01364623 0,02668906 ! skin development GO:0043588 25 15 0,000 0,01364623 0,02666638 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,01364623 0,02664375 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,01364623 0,02662115 ! lipid phosphorylation GO:0046834 23 15 0,000 0,01364623 0,02659859 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,01364623 0,02657607 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,01364623 0,02655358 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,01364623 0,02653114 ! bile acid metabolic process GO:0008206 22 15 0,000 0,01364623 0,02650873 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,01364623 0,02648636 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,01364623 0,02646402 ! adult walking behavior GO:0007628 25 15 0,000 0,01364623 0,02644173 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,01364623 0,02641947 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,01364623 0,02639725 ! myoblast differentiation GO:0045445 27 15 0,000 0,01364623 0,02637507 ! centrosome cycle GO:0007098 16 15 0,000 0,01364623 0,02635292 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,01364623 0,02633082 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,01364623 0,02630875 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,01364623 0,02628671 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,01364623 0,02626471 ! cerebral cortex development GO:0021987 29 15 0,000 0,01364623 0,02624275 ! response to osmotic stress GO:0006970 22 15 0,000 0,01364623 0,02622083 ! vesicle coating GO:0006901 25 15 0,000 0,01364623 0,02619894 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,01364623 0,02617709 ! DNA integration GO:0015074 22 15 0,000 0,01364623 0,02615528 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,01364623 0,0261335 ! peptide secretion GO:0002790 27 15 0,000 0,01364623 0,02611176 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,01364623 0,02609005 ! regulation of vasodilation GO:0042312 24 15 0,000 0,01364623 0,02606838 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,01364623 0,02604675 ! neuron recognition GO:0008038 22 15 0,000 0,01364623 0,02602515 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,01364623 0,02600359 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,01364623 0,02598206 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,01364623 0,02596057 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,01364623 0,02593912 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,01364623 0,0259177 ! biomineral formation GO:0031214 18 15 0,000 0,01364623 0,02589631 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,01364623 0,02587497 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,01364623 0,02585365 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,01364623 0,02583237 ! dopamine metabolic process GO:0042417 30 15 0,000 0,01364623 0,02581113 ! organic cation transport GO:0015695 19 15 0,000 0,01364623 0,02578992 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,01364623 0,02576875 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,01364623 0,02574761 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,01364623 0,0257265 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,01364623 0,02570543 ! defense response to virus GO:0051607 27 15 0,000 0,01364623 0,0256844 ! peptide hormone processing GO:0016486 19 15 0,000 0,01364623 0,0256634 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,01364623 0,02564243 ! protein secretion GO:0009306 27 16 0,000 0,01454974 0,02731789 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,01454974 0,02729561 ! hormone secretion GO:0046879 25 16 0,000 0,01454974 0,02727336 ! bone remodeling GO:0046849 24 16 0,000 0,01454974 0,02725115 ! endothelial cell migration GO:0043542 22 16 0,000 0,01454974 0,02722898 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,01454974 0,02720684 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,01454974 0,02718474 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,01454974 0,02716267 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,01454974 0,02714064 ! glial cell development GO:0021782 24 16 0,000 0,01454974 0,02711865 ! patterning of blood vessels GO:0001569 24 16 0,000 0,01454974 0,02709669 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,01454974 0,02707477 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,01454974 0,02705288 ! protein polyubiquitination GO:0000209 26 16 0,000 0,01454974 0,02703103 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,01454974 0,02700921 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,01454974 0,02698743 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,01454974 0,02696568 ! regulation of protein binding GO:0043393 27 16 0,000 0,01454974 0,02694397 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,01454974 0,0269223 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,01454974 0,02690065 ! protein export from nucleus GO:0006611 24 16 0,000 0,01454974 0,02687905 ! negative regulation of immune response GO:0050777 28 16 0,000 0,01454974 0,02685747 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,01454974 0,02683594 ! DNA replication initiation GO:0006270 25 16 0,000 0,01454974 0,02681443 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,01454974 0,02679296 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,01454974 0,02677153 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,01454974 0,02675013 ! diencephalon development GO:0021536 25 16 0,000 0,01454974 0,02672876 ! oogenesis GO:0048477 23 16 0,000 0,01454974 0,02670743 ! neural crest cell migration GO:0001755 24 16 0,000 0,01454974 0,02668613 ! G1 phase GO:0051318 27 16 0,000 0,01454974 0,02666487 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,01454974 0,02664364 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,01454974 0,02662244 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,01454974 0,02660128 ! steroid catabolic process GO:0006706 22 16 0,000 0,01454974 0,02658015 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,01454974 0,02655906 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,01454974 0,026538 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,01454974 0,02651697 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,01454974 0,02649597 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,01454974 0,02647501 ! sperm-egg recognition GO:0035036 16 16 0,000 0,01454974 0,02645408 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,01454974 0,02643319 ! nerve development GO:0021675 18 16 0,000 0,01454974 0,02641232 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,01454974 0,02639149 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,01454974 0,0263707 ! negative regulation of translation GO:0017148 22 16 0,000 0,01454974 0,02634993 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,01545248 0,02796279 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,01545248 0,02794081 ! negative regulation of defense response GO:0031348 19 17 0,000 0,01545248 0,02791886 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,01545248 0,02789695 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,01545248 0,02787507 ! glycerol metabolic process GO:0006071 20 17 0,000 0,01545248 0,02785322 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,01545248 0,02783141 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,01545248 0,02780963 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,01545248 0,02778789 ! signal complex assembly GO:0007172 29 17 0,000 0,01545248 0,02776618 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,01545248 0,0277445 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,01545248 0,02772286 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,01545248 0,02770125 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,01545248 0,02767968 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,01545248 0,02765814 ! memory GO:0007613 25 17 0,000 0,01545248 0,02763663 ! keratinization GO:0031424 17 17 0,000 0,01545248 0,02761516 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,01545248 0,02759372 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,01545248 0,02757231 ! retinoid metabolic process GO:0001523 22 17 0,000 0,01545248 0,02755094 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,01545248 0,0275296 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,01545248 0,02750829 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,01545248 0,02748701 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,01545248 0,02746577 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,01545248 0,02744456 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,01545248 0,02742339 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 0,000 0,01545248 0,02740224 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,01545248 0,02738113 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,01545248 0,02736005 ! membrane budding GO:0006900 29 17 0,000 0,01545248 0,02733901 ! heme metabolic process GO:0042168 27 17 0,000 0,01545248 0,02731799 ! actin filament bundle formation GO:0051017 26 17 0,000 0,01545248 0,02729701 ! neuromuscular junction development GO:0007528 23 17 0,000 0,01545248 0,02727606 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,01545248 0,02725514 ! body fluid secretion GO:0007589 27 17 0,000 0,01545248 0,02723426 ! stem cell differentiation GO:0048863 36 17 0,000 0,01545248 0,02721341 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,01545248 0,02719258 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,01545248 0,0271718 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,01545248 0,02715104 ! sensory perception of pain GO:0019233 23 17 0,000 0,01545248 0,02713031 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,01545248 0,02710962 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,01545248 0,02708895 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,01545248 0,02706832 ! synaptogenesis GO:0007416 24 17 0,000 0,01545248 0,02704772 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,01545248 0,02702715 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,01545248 0,02700662 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,01545248 0,02698611 ! cell-cell junction organization GO:0045216 25 17 0,000 0,01545248 0,02696564 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,01545248 0,02694519 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,01545248 0,02692478 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,01545248 0,0269044 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,01545248 0,02688405 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,01545248 0,02686373 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,01545248 0,02684344 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,01635444 0,02838885 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,01635444 0,02836744 ! positive regulation of translation GO:0045727 28 18 0,000 0,01635444 0,02834606 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,01635444 0,02832471 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,01635444 0,0283034 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,01635444 0,02828212 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,01635444 0,02826087 ! cAMP metabolic process GO:0046058 33 18 0,000 0,01635444 0,02823965 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,01635444 0,02821847 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,01635444 0,02819732 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,01635444 0,02817619 ! axis specification GO:0009798 26 18 0,000 0,01635444 0,0281551 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,01635444 0,02813405 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,01635444 0,02811302 ! pancreas development GO:0031016 26 18 0,000 0,01635444 0,02809202 ! apoptotic mitochondrial changes GO:0008637 29 18 0,000 0,01635444 0,02807106 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,01635444 0,02805013 ! glutamine metabolic process GO:0006541 23 18 0,000 0,01635444 0,02802923 ! response to retinoic acid GO:0032526 25 18 0,000 0,01635444 0,02800835 ! pigmentation during development GO:0048066 31 18 0,000 0,01635444 0,02798751 ! central nervous system neuron development GO:0021954 30 18 0,000 0,01635444 0,02796671 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,01635444 0,02794593 ! fucose metabolic process GO:0006004 26 18 0,000 0,01635444 0,02792518 ! response to fungus GO:0009620 19 18 0,000 0,01635444 0,02790447 ! peptide cross-linking GO:0018149 31 18 0,000 0,01635444 0,02788378 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,01635444 0,02786313 ! heart process GO:0003015 27 18 0,000 0,01635444 0,0278425 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,01635444 0,02782191 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,01635444 0,02780135 ! visual learning GO:0008542 35 18 0,000 0,01635444 0,02778081 ! somitogenesis GO:0001756 24 18 0,000 0,01635444 0,02776031 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,01635444 0,02773984 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,01635444 0,0277194 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,01635444 0,02769898 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,01635444 0,0276786 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,01635444 0,02765825 ! vitamin transport GO:0051180 24 18 0,000 0,01635444 0,02763793 ! hormone transport GO:0009914 27 18 0,000 0,01635444 0,02761764 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,01635444 0,02759737 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,01635444 0,02757714 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,01635444 0,02755694 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,01635444 0,02753676 ! cell-cell recognition GO:0009988 20 18 0,000 0,01635444 0,02751662 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,01635444 0,02749651 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,01635444 0,02747642 ! regulation of glucose import GO:0046324 21 18 0,000 0,01635444 0,02745637 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,01635444 0,02743634 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,01635444 0,02741634 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,01635444 0,02739637 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,01635444 0,02737643 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,01725563 0,02886396 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,01725563 0,02884299 ! positive regulation of fibroblast proliferation GO:0048146 27 19 0,000 0,01725563 0,02882204 ! positive regulation of ossification GO:0045778 30 19 0,000 0,01725563 0,02880112 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,01725563 0,02878024 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,01725563 0,02875938 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,01725563 0,02873856 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,01725563 0,02871776 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,01725563 0,028697 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,01725563 0,02867626 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,01725563 0,02865556 ! regeneration GO:0031099 32 19 0,000 0,01725563 0,02863488 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,01725563 0,02861424 ! response to alkaloid GO:0043279 32 19 0,000 0,01725563 0,02859362 ! sensory perception of taste GO:0050909 23 19 0,000 0,01725563 0,02857304 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,01725563 0,02855248 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 0,000 0,01725563 0,02853196 ! smooth muscle contraction GO:0006939 36 19 0,000 0,01725563 0,02851146 ! peroxisome organization GO:0007031 29 19 0,000 0,01725563 0,02849099 ! digestive system process GO:0022600 30 19 0,000 0,01725563 0,02847055 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,01725563 0,02845014 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,01725563 0,02842976 ! response to vitamin A GO:0033189 26 19 0,000 0,01725563 0,02840941 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,01725563 0,02838909 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,01725563 0,0283688 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,01725563 0,02834854 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,01725563 0,0283283 ! response to starvation GO:0042594 30 19 0,000 0,01725563 0,0283081 ! sex determination GO:0007530 29 19 0,000 0,01725563 0,02828792 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,01725563 0,02826777 ! plasma membrane fusion GO:0045026 23 19 0,000 0,01725563 0,02824765 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,01725563 0,02822756 ! cytolysis GO:0019835 20 19 0,000 0,01725563 0,0282075 ! renal system process GO:0003014 35 19 0,000 0,01725563 0,02818746 ! vasodilation GO:0042311 33 19 0,000 0,01725563 0,02816746 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,01725563 0,02814748 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,01725563 0,02812753 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,01725563 0,02810761 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,01725563 0,02808772 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,01725563 0,02806786 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,01725563 0,02804802 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,01725563 0,02802821 ! sarcomere organization GO:0045214 23 19 0,000 0,01725563 0,02800843 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,01725563 0,02798868 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,01725563 0,02796896 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,01725563 0,02794926 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,01725563 0,02792959 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,01725563 0,02790995 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,01725563 0,02789034 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,01725563 0,02787075 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,01725563 0,02785119 ! protein stabilization GO:0050821 26 19 0,000 0,01725563 0,02783166 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,01815604 0,02926342 ! iron ion transport GO:0006826 37 20 0,000 0,01815604 0,02924293 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,01815604 0,02922246 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,01815604 0,02920203 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,01815604 0,02918162 ! response to vitamin GO:0033273 29 20 0,000 0,01815604 0,02916124 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,01815604 0,02914089 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,01815604 0,02912057 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,01815604 0,02910028 ! spinal cord development GO:0021510 31 20 0,000 0,01815604 0,02908001 ! response to ethanol GO:0045471 37 20 0,000 0,01815604 0,02905978 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,01815604 0,02903957 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 0,000 0,01815604 0,02901939 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,01815604 0,02899924 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,01815604 0,02897911 ! chromosome condensation GO:0030261 31 20 0,000 0,01815604 0,02895902 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,01815604 0,02893895 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,01815604 0,02891891 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,01815604 0,02889889 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,01815604 0,02887891 ! pallium development GO:0021543 38 20 0,000 0,01815604 0,02885895 ! DNA modification GO:0006304 28 20 0,000 0,01815604 0,02883902 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,01815604 0,02881912 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,01815604 0,02879924 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,01815604 0,02877939 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,01815604 0,02875957 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,01815604 0,02873978 ! positive regulation of B cell activation GO:0050871 31 20 0,000 0,01815604 0,02872001 ! collagen catabolic process GO:0030574 25 20 0,000 0,01815604 0,02870027 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,01815604 0,02868056 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,01815604 0,02866088 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,01815604 0,02864122 ! actin filament-based movement GO:0030048 34 20 0,000 0,01815604 0,02862159 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,01905568 0,03001923 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,01905568 0,02999868 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,01905568 0,02997816 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,01905568 0,02995767 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 0,000 0,01905568 0,02993721 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,01905568 0,02991677 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,01905568 0,02989636 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,01905568 0,02987599 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,01905568 0,02985563 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,01905568 0,02983531 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,01905568 0,02981501 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,01905568 0,02979475 ! protein amino acid acylation GO:0043543 37 21 0,000 0,01905568 0,0297745 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,01905568 0,02975429 ! vesicle docking GO:0048278 27 21 0,000 0,01905568 0,0297341 ! phototransduction GO:0007602 25 21 0,000 0,01905568 0,02971395 ! dendrite development GO:0016358 35 21 0,000 0,01905568 0,02969381 ! visual behavior GO:0007632 39 21 0,000 0,01905568 0,02967371 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,01905568 0,02965363 ! ovarian follicle development GO:0001541 30 21 0,000 0,01905568 0,02963358 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,01905568 0,02961356 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,01905568 0,02959357 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,01905568 0,0295736 ! cell aging GO:0007569 32 21 0,000 0,01905568 0,02955365 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,01905568 0,02953374 ! response to endoplasmic reticulum stress GO:0034976 25 21 0,000 0,01905568 0,02951385 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,01905568 0,02949399 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,01905568 0,02947416 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,01905568 0,02945435 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,01905568 0,02943457 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,01905568 0,02941481 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,01905568 0,02939508 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,01905568 0,02937538 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,01905568 0,02935571 ! fatty acid transport GO:0015908 30 21 0,000 0,01905568 0,02933606 ! immunoglobulin production GO:0002377 33 21 0,000 0,01905568 0,02931643 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,01905568 0,02929684 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,01905568 0,02927727 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,01905568 0,02925772 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,01905568 0,02923821 ! cellular response to extracellular stimulus GO:0031668 32 21 0,000 0,01905568 0,02921871 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,01905568 0,02919925 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,01905568 0,02917981 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,01905568 0,02916039 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,01905568 0,029141 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,01905568 0,02912164 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,01905568 0,0291023 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,01905568 0,02908299 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,01905568 0,02906371 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,01905568 0,02904445 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,01905568 0,02902521 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,01995455 0,03037423 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,01995455 0,03035414 ! regulation of fibroblast proliferation GO:0048145 35 22 0,000 0,01995455 0,03033408 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,01995455 0,03031404 ! viral genome replication GO:0019079 29 22 0,000 0,01995455 0,03029404 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,01995455 0,03027405 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,01995455 0,0302541 ! leukocyte adhesion GO:0007159 38 22 0,000 0,01995455 0,03023417 ! molting cycle process GO:0022404 40 22 0,000 0,01995455 0,03021426 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,01995455 0,03019438 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,01995455 0,03017453 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,01995455 0,03015471 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,01995455 0,03013491 ! vasculogenesis GO:0001570 33 22 0,000 0,01995455 0,03011513 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,01995455 0,03009539 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,01995455 0,03007566 GO:0010810|regulation of cell-substrate adhesion, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,01995455 0,03005597 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,01995455 0,0300363 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,01995455 0,03001665 ! lysosome organization GO:0007040 37 22 0,000 0,01995455 0,02999703 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,01995455 0,02997744 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,01995455 0,02995787 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,01995455 0,02993833 ! regulation of behavior GO:0050795 38 22 0,000 0,01995455 0,02991882 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,01995455 0,02989932 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,01995455 0,02987986 ! membrane depolarization GO:0051899 35 22 0,000 0,01995455 0,02986042 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,01995455 0,029841 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,01995455 0,02982161 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,01995455 0,02980225 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,01995455 0,02978291 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,01995455 0,02976359 ! blastocyst development GO:0001824 37 22 0,000 0,01995455 0,02974431 ! neural tube closure GO:0001843 33 22 0,000 0,01995455 0,02972504 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,01995455 0,0297058 ! protein tetramerization GO:0051262 39 22 0,000 0,01995455 0,02968659 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,02085264 0,03100264 ! neuron fate commitment GO:0048663 32 23 0,000 0,02085264 0,03098261 ! embryonic pattern specification GO:0009880 31 23 0,000 0,02085264 0,03096261 ! positive regulation of cell adhesion GO:0045785 37 23 0,000 0,02085264 0,03094263 ! myelination GO:0042552 35 23 0,000 0,02085264 0,03092268 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,02085264 0,03090276 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,02085264 0,03088286 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,02085264 0,03086299 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,02085264 0,03084314 ! ER-nuclear signaling pathway GO:0006984 27 23 0,000 0,02085264 0,03082332 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,02085264 0,03080352 ! vesicle targeting GO:0006903 32 23 0,000 0,02085264 0,03078375 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,02085264 0,030764 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,02085264 0,03074428 ! osteoblast differentiation GO:0001649 40 23 0,000 0,02085264 0,03072459 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,02085264 0,03070492 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,02085264 0,03068527 ! interaction with host GO:0051701 37 23 0,000 0,02085264 0,03066565 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,02085264 0,03064606 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,02085264 0,03062649 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,02085264 0,03060694 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,02085264 0,03058742 ! negative regulation of phosphorylation GO:0042326 41 23 0,000 0,02085264 0,03056793 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,02085264 0,03054846 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,02085264 0,03052901 ! cell fate determination GO:0001709 45 23 0,000 0,02085264 0,03050959 ! pentose metabolic process GO:0019321 31 23 0,000 0,02085264 0,0304902 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,02085264 0,03047083 ! spermatid development GO:0007286 33 23 0,000 0,02085264 0,03045148 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,02085264 0,03043216 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,02085264 0,03041286 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,02085264 0,03039359 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,02085264 0,03037434 ! telomere organization GO:0032200 32 23 0,000 0,02085264 0,03035511 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,02085264 0,03033591 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,02085264 0,03031674 ! regulation of amine transport GO:0051952 38 23 0,000 0,02085264 0,03029759 ! liver development GO:0001889 40 23 0,000 0,02085264 0,03027846 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,02174997 0,03156147 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,02174997 0,03154157 ! initiation of viral infection GO:0019059 42 24 0,000 0,02174997 0,03152169 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,02174997 0,03150184 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,02174997 0,03148202 ! superoxide metabolic process GO:0006801 32 24 0,000 0,02174997 0,03146222 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,02174997 0,03144244 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! insulin receptor signaling pathway GO:0008286 40 24 0,000 0,02174997 0,03142269 ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,02174997 0,03140296 ! fat cell differentiation GO:0045444 37 24 0,000 0,02174997 0,03138326 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,02174997 0,03136359 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,02174997 0,03134394 ! vacuole organization GO:0007033 39 24 0,000 0,02174997 0,03132431 ! receptor metabolic process GO:0043112 37 24 0,000 0,02174997 0,03130471 ! neural crest cell development GO:0014032 39 24 0,000 0,02174997 0,03128513 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,02174997 0,03126558 ! primary neural tube formation GO:0014020 35 24 0,000 0,02174997 0,03124605 ! negative regulation of cell development GO:0010721 56 24 0,000 0,02174997 0,03122654 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,02174997 0,03120706 ! base-excision repair GO:0006284 31 24 0,000 0,02174997 0,03118761 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,02174997 0,03116818 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,02174997 0,03114877 ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,02174997 0,03112939 ! glutathione metabolic process GO:0006749 29 24 0,000 0,02174997 0,03111003 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,02174997 0,03109069 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,02174997 0,03107138 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,02174997 0,03105209 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,02264652 0,03231203 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,02264652 0,032292 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,02264652 0,03227199 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,02264652 0,03225201 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,02264652 0,03223205 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,02264652 0,03221212 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 0,000 0,02264652 0,03219221 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,02264652 0,03217232 ! peptide transport GO:0015833 43 25 0,000 0,02264652 0,03215246 ! male gonad development GO:0008584 33 25 0,000 0,02264652 0,03213263 ! iron ion homeostasis GO:0055072 39 25 0,000 0,02264652 0,03211282 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,02264652 0,03209303 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,02264652 0,03207327 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,02264652 0,03205353 ! phospholipid transport GO:0015914 35 25 0,000 0,02264652 0,03203382 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,02264652 0,03201413 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,02264652 0,03199447 ! detection of light stimulus GO:0009583 30 25 0,000 0,02264652 0,03197483 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,02264652 0,03195521 GO:0045840|positive regulation of mitosis, ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,02264652 0,03193562 ! leukocyte proliferation GO:0070661 39 25 0,000 0,02264652 0,03191605 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,02264652 0,0318965 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,0235423 0,03313788 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,0235423 0,03311761 ! translational initiation GO:0006413 43 26 0,000 0,0235423 0,03309736 ! regulation of pH GO:0006885 36 26 0,000 0,0235423 0,03307715 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 0,000 0,0235423 0,03305695 ! circadian rhythm GO:0007623 42 26 0,000 0,0235423 0,03303678 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,0235423 0,03301664 ! post-embryonic development GO:0009791 42 26 0,000 0,0235423 0,03299652 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,0235423 0,03297642 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,0235423 0,03295635 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,0235423 0,03293631 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,0235423 0,03291629 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,0235423 0,03289629 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,0235423 0,03287631 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,0235423 0,03285636 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,0235423 0,03283644 ! regulation of coagulation GO:0050818 39 26 0,000 0,0235423 0,03281654 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,02443731 0,0340435 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,02443731 0,03402289 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,02443731 0,03400231 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,02443731 0,03398175 ! membrane docking GO:0022406 39 27 0,000 0,02443731 0,03396122 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,02443731 0,03394071 ! catechol metabolic process GO:0009712 43 27 0,000 0,02443731 0,03392023 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,02443731 0,03389977 ! acute-phase response GO:0006953 42 27 0,000 0,02443731 0,03387933 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,02443731 0,03385893 ! myofibril assembly GO:0030239 36 27 0,000 0,02443731 0,03383854 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,02443731 0,03381818 ! response to ionizing radiation GO:0010212 47 27 0,000 0,02443731 0,03379784 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,02443731 0,03377753 ! natural killer cell activation GO:0030101 35 27 0,000 0,02443731 0,03375725 ! lipid oxidation GO:0034440 38 27 0,000 0,02443731 0,03373698 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,02443731 0,03371675 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,02443731 0,03369653 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,02443731 0,03367634 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,02443731 0,03365618 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,02443731 0,03363604 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,02443731 0,03361592 ! gene silencing GO:0016458 41 27 0,000 0,02443731 0,03359583 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,02533155 0,0348044 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,02533155 0,03478363 ! phenol metabolic process GO:0018958 44 28 0,000 0,02533155 0,03476287 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,02533155 0,03474214 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,02533155 0,03472144 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,02533155 0,03470076 ! cell junction assembly GO:0034329 56 28 0,000 0,02533155 0,0346801 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,02533155 0,03465947 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,02533155 0,03463887 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,02533155 0,03461828 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,02533155 0,03459773 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,02533155 0,03457719 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,02533155 0,03455669 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,02533155 0,0345362 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,02533155 0,03451574 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,02533155 0,03449531 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,02533155 0,0344749 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,02533155 0,03445451 ! mesoderm formation GO:0001707 46 28 0,000 0,02533155 0,03443415 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,02533155 0,03441381 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,02533155 0,03439349 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,02533155 0,0343732 ! ensheathment of neurons GO:0007272 43 28 0,000 0,02533155 0,03435293 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,02533155 0,03433269 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,02533155 0,03431247 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,02533155 0,03429227 ! neural tube formation GO:0001841 41 28 0,000 0,02533155 0,0342721 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,02533155 0,03425195 ! placenta development GO:0001890 37 28 0,000 0,02533155 0,03423183 ! regulation of B cell activation GO:0050864 42 28 0,000 0,02533155 0,03421173 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,02622503 0,03539763 ! regulation of innate immune response GO:0045088 38 29 0,000 0,02622503 0,03537687 ! ovulation cycle process GO:0022602 41 29 0,000 0,02622503 0,03535613 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,02622503 0,03533542 ! protein targeting to membrane GO:0006612 53 29 0,000 0,02622503 0,03531473 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,02622503 0,03529407 ! mismatch repair GO:0006298 34 29 0,000 0,02622503 0,03527343 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,02622503 0,03525281 ! muscle cell development GO:0055001 38 29 0,000 0,02622503 0,03523222 ! formation of primary germ layer GO:0001704 48 29 0,000 0,02622503 0,03521165 ! telencephalon development GO:0021537 52 29 0,000 0,02622503 0,03519111 ! eye morphogenesis GO:0048592 51 29 0,000 0,02622503 0,03517059 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,02622503 0,0351501 ! tissue homeostasis GO:0001894 42 29 0,000 0,02622503 0,03512962 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,02711773 0,0363043 ! collagen metabolic process GO:0032963 40 30 0,000 0,02711773 0,03628318 ! organic anion transport GO:0015711 51 30 0,000 0,02711773 0,03626209 ! cholesterol transport GO:0030301 46 30 0,000 0,02711773 0,03624102 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,02711773 0,03621997 ! spliceosome assembly GO:0000245 49 30 0,000 0,02711773 0,03619895 ! spindle organization GO:0007051 37 30 0,000 0,02711773 0,03617795 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,02711773 0,03615698 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,02711773 0,03613603 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,02711773 0,03611511 ! ceramide metabolic process GO:0006672 43 30 0,000 0,02711773 0,03609421 ! ovulation cycle GO:0042698 43 30 0,000 0,02711773 0,03607333 ! hindbrain development GO:0030902 45 30 0,000 0,02711773 0,03605248 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,02711773 0,03603165 ! adult locomotory behavior GO:0008344 47 30 0,000 0,02711773 0,03601085 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,02711773 0,03599007 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,02711773 0,03596931 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,02711773 0,03594858 ! response to heat GO:0009408 41 30 0,000 0,02711773 0,03592787 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,02711773 0,03590719 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,02711773 0,03588653 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,02800967 0,03704557 ! negative regulation of secretion GO:0051048 49 31 0,000 0,02800967 0,03702428 ! mammary gland development GO:0030879 57 31 0,000 0,02800967 0,03700301 ! glial cell differentiation GO:0010001 55 31 0,000 0,02800967 0,03698177 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,02800967 0,03696055 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,02800967 0,03693936 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,02800967 0,03691819 ! odontogenesis GO:0042476 50 31 0,000 0,02800967 0,03689705 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,02800967 0,03687593 ! segmentation GO:0035282 41 31 0,000 0,02800967 0,03685483 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,02800967 0,03683376 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,02800967 0,03681271 ! metanephros development GO:0001656 58 31 0,000 0,02800967 0,03679169 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,02800967 0,03677069 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,02800967 0,03674971 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,02800967 0,03672876 ! cell fate specification GO:0001708 37 31 0,000 0,02800967 0,03670783 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,02800967 0,03668693 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,02800967 0,03666605 ! RNA modification GO:0009451 40 31 0,000 0,02800967 0,03664519 ! regulation of muscle development GO:0048634 48 32 0,000 0,02890084 0,03778962 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,02890084 0,03776815 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,02890084 0,0377467 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,02890084 0,03772528 ! meiosis I GO:0007127 52 32 0,000 0,02890084 0,03770388 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,02890084 0,03768251 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,02890084 0,03766116 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,02890084 0,03763983 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,02890084 0,03761853 ! peripheral nervous system development GO:0007422 53 32 0,000 0,02890084 0,03759725 ! regulation of protein stability GO:0031647 48 32 0,000 0,02890084 0,037576 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,02890084 0,03755477 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,02890084 0,03753356 ! cytokine production GO:0001816 44 32 0,000 0,02890084 0,03751238 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,02890084 0,03749123 ! vesicle localization GO:0051648 47 32 0,000 0,02890084 0,03747009 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,02979125 0,03860275 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,02979125 0,03858101 ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,02979125 0,0385593 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,02979125 0,03853761 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,02979125 0,03851595 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,02979125 0,03849431 ! sister chromatid segregation GO:0000819 46 33 0,000 0,02979125 0,0384727 ! ear morphogenesis GO:0042471 42 33 0,000 0,02979125 0,03845111 ! actomyosin structure organization GO:0031032 43 33 0,000 0,02979125 0,03842954 ! cell junction organization GO:0034330 63 33 0,000 0,02979125 0,038408 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,02979125 0,03838649 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,02979125 0,03836499 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,02979125 0,03834352 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 0,000 0,02979125 0,03832208 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,02979125 0,03830066 ! female gonad development GO:0008585 49 33 0,000 0,02979125 0,03827926 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,02979125 0,03825789 ! positive regulation of cell development GO:0010720 54 33 0,000 0,02979125 0,03823654 ! lipid homeostasis GO:0055088 55 33 0,000 0,02979125 0,03821521 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,02979125 0,03819391 ! regulation of proteolysis GO:0030162 50 33 0,000 0,02979125 0,03817263 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,02979125 0,03815138 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,02979125 0,03813015 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,02979125 0,03810894 ! cytokinesis GO:0000910 52 33 0,000 0,02979125 0,03808776 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,02979125 0,0380666 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,03068089 0,03918159 ! mRNA catabolic process GO:0006402 48 34 0,000 0,03068089 0,03915985 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,03068089 0,03913813 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,03068089 0,03911644 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,03068089 0,03909476 ! feeding behavior GO:0007631 45 34 0,000 0,03068089 0,03907312 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,03068089 0,03905149 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,03068089 0,0390299 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,03068089 0,03900832 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,03068089 0,03898677 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,03068089 0,03896524 ! neuron migration GO:0001764 46 34 0,000 0,03068089 0,03894374 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,03068089 0,03892226 ! female gamete generation GO:0007292 43 34 0,000 0,03068089 0,0389008 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,03068089 0,03887937 ! aerobic respiration GO:0009060 47 34 0,000 0,03068089 0,03885796 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,03068089 0,03883657 ! cellular response to insulin stimulus GO:0032869 52 34 0,000 0,03068089 0,03881521 ! embryonic organ development GO:0048568 45 34 0,000 0,03068089 0,03879387 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,03068089 0,03877256 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,03156977 0,03987395 ! Notch signaling pathway GO:0007219 56 35 0,000 0,03156977 0,03985207 ! regulation of intracellular protein transport GO:0033157 59 35 0,000 0,03156977 0,03983021 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,03156977 0,03980837 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,03156977 0,03978656 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,03156977 0,03976477 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,03156977 0,039743 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,03156977 0,03972126 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,03156977 0,03969954 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,03156977 0,03967785 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,03156977 0,03965618 ! glycogen metabolic process GO:0005977 48 35 0,000 0,03156977 0,03963453 ! pigment metabolic process GO:0042440 61 35 0,000 0,03156977 0,03961291 ! positive regulation of leukocyte proliferation GO:0070665 50 35 0,000 0,03156977 0,03959131 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! protein homooligomerization GO:0051260 52 35 0,000 0,03156977 0,03956974 ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,03245788 0,04066074 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 0,000 0,03245788 0,04063861 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,03245788 0,0406165 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,03245788 0,04059441 ! negative regulation of binding GO:0051100 58 36 0,000 0,03245788 0,04057235 ! organic ether metabolic process GO:0018904 46 36 0,000 0,03245788 0,04055031 ! tissue remodeling GO:0048771 62 36 0,000 0,03245788 0,0405283 ! neural tube development GO:0021915 50 36 0,000 0,03245788 0,04050631 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,03245788 0,04048434 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,03245788 0,0404624 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,03245788 0,04044048 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,03245788 0,04041858 ! glucan metabolic process GO:0044042 49 36 0,000 0,03245788 0,04039671 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,03334523 0,04147865 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,03334523 0,04145623 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,03334523 0,04143383 ! learning GO:0007612 67 37 0,000 0,03334523 0,04141146 ! ion transmembrane transport GO:0034220 56 37 0,000 0,03334523 0,04138911 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,03334523 0,04136679 ! regulation of protein secretion GO:0050708 51 37 0,000 0,03334523 0,04134449 ! amino acid activation GO:0043038 52 37 0,000 0,03334523 0,04132221 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,03334523 0,04129996 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,03423181 0,04237522 ! gliogenesis GO:0042063 71 38 0,000 0,03423181 0,04235243 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,03423181 0,04232966 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,03423181 0,04230691 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,03423181 0,04228419 ! phagocytosis GO:0006909 60 38 0,000 0,03423181 0,0422615 ! mesenchymal cell development GO:0014031 64 38 0,000 0,03423181 0,04223882 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 0,000 0,03423181 0,04221618 ! maintenance of location in cell GO:0051651 69 38 0,000 0,03423181 0,04219355 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,03511763 0,04326222 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,03511763 0,04323906 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,03511763 0,04321592 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,03511763 0,04319281 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,03511763 0,04316973 ! regulation of epithelial cell proliferation GO:0050678 71 39 0,000 0,03511763 0,04314667 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,03511763 0,04312363 ! male sex differentiation GO:0046661 53 39 0,000 0,03511763 0,04310062 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,03511763 0,04307763 ! chromatin remodeling GO:0006338 68 39 0,000 0,03511763 0,04305467 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,03511763 0,04303173 ! JNK cascade GO:0007254 54 39 0,000 0,03511763 0,04300882 ! developmental growth GO:0048589 62 39 0,000 0,03511763 0,04298593 ! cell growth GO:0016049 61 39 0,000 0,03511763 0,04296306 ! synapse organization GO:0050808 55 39 0,000 0,03511763 0,04294022 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,0360027 0,04399904 ! response to calcium ion GO:0051592 58 40 0,000 0,0360027 0,04397568 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,0360027 0,04395234 ! regulation of tube size GO:0035150 60 40 0,000 0,0360027 0,04392902 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,0360027 0,04390573 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,0360027 0,04388246 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,0360027 0,04385922 ! peptide metabolic process GO:0006518 56 40 0,000 0,0360027 0,043836 ! induction of apoptosis by intracellular signals GO:0008629 67 40 0,000 0,0360027 0,0438128 ! inner ear development GO:0048839 57 40 0,000 0,0360027 0,04378964 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,0360027 0,04376649 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,0360027 0,04374337 ! double-strand break repair GO:0006302 67 40 0,000 0,0360027 0,04372027 ! B cell differentiation GO:0030183 62 40 0,000 0,0360027 0,0436972 ! epidermal cell differentiation GO:0009913 53 40 0,000 0,0360027 0,04367416 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,0360027 0,04365113 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,0360027 0,04362813 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,0360027 0,04360516 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,036887 0,04465268 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,036887 0,04462919 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,036887 0,04460573 ! glucose transport GO:0015758 52 41 0,000 0,036887 0,04458229 ! endosome transport GO:0016197 71 41 0,000 0,036887 0,04455887 ! striated muscle contraction GO:0006941 62 41 0,000 0,036887 0,04453548 ! positive regulation of DNA binding GO:0043388 57 41 0,000 0,036887 0,04451211 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,036887 0,04448877 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,036887 0,04446546 ! biopolymer methylation GO:0043414 62 41 0,000 0,036887 0,04444216 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,036887 0,0444189 ! mitochondrial transport GO:0006839 60 42 0,000 0,03777053 0,04545904 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,03777053 0,04543527 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 0,000 0,03777053 0,04541152 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,03777053 0,04538779 ! cellular component disassembly GO:0022411 64 42 0,000 0,03777053 0,04536409 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,03777053 0,04534041 ! hexose transport GO:0008645 54 42 0,000 0,03777053 0,04531676 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,03777053 0,04529313 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,03777053 0,04526953 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,03777053 0,04524595 ! excretion GO:0007588 63 42 0,000 0,03777053 0,0452224 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,03777053 0,04519887 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,03777053 0,04517537 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,03777053 0,04515189 ! regulation of cell shape GO:0008360 78 42 0,000 0,03777053 0,04512843 ! positive regulation of binding GO:0051099 59 43 0,000 0,03865331 0,0461592 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 0,000 0,03865331 0,04613525 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,03865331 0,04611132 ! leukocyte migration GO:0050900 60 43 0,000 0,03865331 0,04608741 ! neuromuscular process GO:0050905 79 43 0,000 0,03865331 0,04606353 ! activation of caspase activity GO:0006919 65 43 0,000 0,03865331 0,04603968 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,03865331 0,04601585 ! tRNA processing GO:0008033 49 43 0,000 0,03865331 0,04599204 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,03865331 0,04596826 ! vesicle organization GO:0016050 79 43 0,000 0,03865331 0,04594451 ! response to insulin stimulus GO:0032868 63 43 0,000 0,03865331 0,04592078 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,03865331 0,04589707 ! methylation GO:0032259 64 43 0,000 0,03865331 0,04587339 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,03953533 0,04689596 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,03953533 0,04687179 ! regulation of action potential GO:0001508 71 44 0,000 0,03953533 0,04684764 ! regulation of ion transport GO:0043269 57 44 0,000 0,03953533 0,04682352 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,03953533 0,04679942 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,03953533 0,04677534 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,03953533 0,04675129 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,03953533 0,04672727 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,03953533 0,04670327 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,03953533 0,0466793 ! regulation of mast cell proliferation GO:0070666 64 44 0,000 0,03953533 0,04665535 ! positive regulation of cell cycle GO:0045787 77 45 0,000 0,0404166 0,04767086 ! RNA catabolic process GO:0006401 64 45 0,000 0,0404166 0,04764642 ! positive regulation of defense response GO:0031349 59 45 0,000 0,0404166 0,04762201 ! regulation of translational initiation GO:0006446 64 45 0,000 0,0404166 0,04759763 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,0404166 0,04757327 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,0404166 0,04754894 ! cell recognition GO:0008037 58 45 0,000 0,0404166 0,04752463 ! cell maturation GO:0048469 60 45 0,000 0,0404166 0,04750034 ! protein amino acid autophosphorylation GO:0046777 80 45 0,000 0,0404166 0,04747608 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,0412971 0,04848562 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,0412971 0,04846088 ! cell redox homeostasis GO:0045454 63 46 0,000 0,0412971 0,04843617 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,0412971 0,04841148 ! regulation of ossification GO:0030278 71 46 0,000 0,0412971 0,04838682 ! histone modification GO:0016570 68 46 0,000 0,0412971 0,04836218 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,0412971 0,04833757 ! response to UV GO:0009411 75 46 0,000 0,0412971 0,04831298 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,04217684 0,0493171 ! viral infectious cycle GO:0019058 71 47 0,000 0,04217684 0,04929204 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,04217684 0,04926701 ! endocrine system development GO:0035270 83 47 0,000 0,04217684 0,049242 ! covalent chromatin modification GO:0016569 75 47 0,000 0,04217684 0,04921702 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,04217684 0,04919206 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,04217684 0,04916713 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,04217684 0,04914222 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,04217684 0,04911734 ! regulation of leukocyte proliferation GO:0070663 71 47 0,000 0,04217684 0,04909248 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,04217684 0,04906765 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,04217684 0,04904284 ! chloride transport GO:0006821 67 48 0,000 0,04305583 0,05003962 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,04305583 0,05001435 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 0,000 0,04305583 0,0499891 ! response to temperature stimulus GO:0009266 62 48 0,000 0,04305583 0,04996388 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,04305583 0,04993869 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,04305583 0,04991352 ! gastrulation GO:0007369 73 48 0,000 0,04305583 0,04988837 ! heart morphogenesis GO:0003007 65 48 0,000 0,04305583 0,04986325 ! regulation of DNA replication GO:0006275 75 48 0,000 0,04305583 0,04983816 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,04305583 0,04981309 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,04305583 0,04978804 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,04305583 0,04976302 ! regulation of endocytosis GO:0030100 63 48 0,000 0,04305583 0,04973803 ! nuclear export GO:0051168 69 48 0,000 0,04305583 0,04971306 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,04305583 0,04968812 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,04305583 0,0496632 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,04393407 0,0506508 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,04393407 0,05062543 ! sensory perception of smell GO:0007608 61 49 0,000 0,04393407 0,05060008 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,04393407 0,05057475 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,04393407 0,05054945 ! RNA elongation GO:0006354 62 49 0,000 0,04393407 0,05052418 ! regulation of intracellular transport GO:0032386 78 49 0,000 0,04393407 0,05049893 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,04393407 0,0504737 ! germ cell development GO:0007281 68 49 0,000 0,04393407 0,0504485 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,04393407 0,05042333 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,04393407 0,05039818 ! cartilage development GO:0051216 70 49 0,000 0,04393407 0,05037306 ! maintenance of location GO:0051235 84 49 0,000 0,04393407 0,05034796 ! regulation of actin filament length GO:0030832 72 50 0,000 0,04481154 0,05132796 ! ear development GO:0043583 72 50 0,000 0,04481154 0,05130241 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,04481154 0,05127689 ! membrane fusion GO:0006944 80 50 0,000 0,04481154 0,05125139 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,04481154 0,05122592 ! lipid modification GO:0030258 73 50 0,000 0,04481154 0,05120047 ! positive regulation of growth GO:0045927 67 50 0,000 0,04481154 0,05117505 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,04481154 0,05114965 ! proton transport GO:0015992 75 50 0,000 0,04481154 0,05112428 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,04481154 0,05109893 ! positive regulation of secretion GO:0051047 71 51 0,000 0,04568826 0,05207285 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 0,000 0,04568826 0,05204706 ! hydrogen transport GO:0006818 77 51 0,000 0,04568826 0,05202129 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,04568826 0,05199555 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 0,000 0,04568826 0,05196984 ! positive regulation of cell migration GO:0030335 92 51 0,000 0,04568826 0,05194415 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,04568826 0,05191848 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,04568826 0,05189284 ! adult behavior GO:0030534 80 51 0,000 0,04568826 0,05186723 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,04568826 0,05184164 ! transition metal ion transport GO:0000041 74 52 0,000 0,04656423 0,05280953 ! regulation of cellular component size GO:0032535 74 52 0,000 0,04656423 0,05278351 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,04656423 0,0527575 ! aging GO:0007568 79 52 0,000 0,04656423 0,05273153 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,04656423 0,05270558 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,04656423 0,05267965 ! establishment of organelle localization GO:0051656 85 52 0,000 0,04656423 0,05265375 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,04743945 0,05361706 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,04743945 0,05359073 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,04743945 0,05356442 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,04743945 0,05353814 ! kidney development GO:0001822 90 53 0,000 0,04743945 0,05351188 ! single fertilization GO:0007338 59 53 0,000 0,04743945 0,05348565 ! amino acid transport GO:0006865 84 54 0,000 0,04831391 0,05444487 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,04831391 0,05441821 ! regulation of mitosis GO:0007088 84 54 0,000 0,04831391 0,05439157 GO:0051783|regulation of nuclear division, ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,04831391 0,05436496 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,04831391 0,05433838 ! DNA catabolic process GO:0006308 67 54 0,000 0,04831391 0,05431182 ! detection of external stimulus GO:0009581 66 54 0,000 0,04831391 0,05428529 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,04831391 0,05425878 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,04831391 0,0542323 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,04831391 0,05420585 ! exocytosis GO:0006887 74 55 0,000 0,04918761 0,0551592 ! mesoderm development GO:0007498 76 55 0,000 0,04918761 0,05513232 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,04918761 0,05510546 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,04918761 0,05507863 ! DNA damage response, signal transduction GO:0042770 96 56 0,000 0,05006057 0,05602886 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,05006057 0,05600161 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,05006057 0,05597438 ! positive regulation of cell motion GO:0051272 99 56 0,000 0,05006057 0,05594719 ! negative regulation of protein kinase activity GO:0006469 99 57 0,000 0,05093277 0,05689431 ! carbohydrate transport GO:0008643 74 57 0,000 0,05093277 0,05686669 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,05093277 0,0568391 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 0,000 0,05093277 0,05681153 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,05093277 0,05678399 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,05093277 0,05675648 ! camera-type eye development GO:0043010 88 57 0,000 0,05093277 0,056729 ! secondary metabolic process GO:0019748 84 57 0,000 0,05093277 0,05670154 ! response to peptide hormone stimulus GO:0043434 84 57 0,000 0,05093277 0,05667411 ! developmental maturation GO:0021700 75 57 0,000 0,05093277 0,0566467 ! gonad development GO:0008406 79 57 0,000 0,05093277 0,05661932 ! negative regulation of kinase activity GO:0033673 100 58 0,000 0,05180423 0,05756025 ! viral reproductive process GO:0022415 87 58 0,000 0,05180423 0,05753246 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,05180423 0,05750469 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,05180423 0,05747695 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,05180423 0,05744924 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,05267493 0,05838667 ! lung development GO:0030324 94 59 0,000 0,05267493 0,05835854 ! actin filament organization GO:0007015 95 59 0,000 0,05267493 0,05833045 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,05267493 0,05830238 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,05267493 0,05827433 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,05354488 0,05920828 ! phosphoinositide metabolic process GO:0030384 87 60 0,000 0,05354488 0,05917983 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,05354488 0,05915141 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,05354488 0,05912301 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,05354488 0,05909464 ! regulation of heart contraction GO:0008016 91 60 0,000 0,05354488 0,0590663 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,05354488 0,05903798 ! fertilization GO:0009566 68 60 0,000 0,05354488 0,05900969 ! regulation of homeostatic process GO:0032844 105 60 0,000 0,05354488 0,05898143 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,05441409 0,0599102 ! meiosis GO:0007126 96 61 0,000 0,05441409 0,05988153 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 114 61 0,000 0,05441409 0,05985289 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,05441409 0,05982428 ! urogenital system development GO:0001655 101 61 0,000 0,05441409 0,0597957 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,05441409 0,05976715 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,05441409 0,05973862 ! extracellular matrix organization GO:0030198 103 61 0,000 0,05441409 0,05971012 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,05441409 0,05968164 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! negative regulation of transferase activity GO:0051348 105 61 0,000 0,05441409 0,05965319 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 0,000 0,05441409 0,05962477 ! amine catabolic process GO:0009310 90 62 0,000 0,05528254 0,06054755 ! neurotransmitter transport GO:0006836 81 62 0,000 0,05528254 0,06051873 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,05528254 0,06048994 ! respiratory tube development GO:0030323 99 62 0,000 0,05528254 0,06046118 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,05528254 0,06043244 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 0,000 0,05528254 0,06040373 ! meiotic cell cycle GO:0051321 97 62 0,000 0,05528254 0,06037505 ! organelle localization GO:0051640 96 62 0,000 0,05528254 0,06034639 ! regulation of transcription factor activity GO:0051090 97 63 0,000 0,05615025 0,06126451 GO:0090046|regulation of transcription regulator activity, ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,05615025 0,06123546 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 0,000 0,05615025 0,06120644 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 0,000 0,05615025 0,06117744 ! viral reproduction GO:0016032 92 63 0,000 0,05615025 0,06114848 ! regulation of lipase activity GO:0060191 109 63 0,000 0,05615025 0,06111954 ! cell cycle checkpoint GO:0000075 108 64 0,000 0,05701721 0,06203387 ! appendage morphogenesis GO:0035107 93 64 0,000 0,05701721 0,06200453 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,05701721 0,06197523 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,05701721 0,06194596 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 0,000 0,05701721 0,06191671 ! respiratory system development GO:0060541 100 64 0,000 0,05701721 0,06188749 ! adaptive immune response GO:0002250 94 64 0,000 0,05701721 0,0618583 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 90 65 0,000 0,05788343 0,06276845 ! regulation of caspase activity GO:0043281 97 65 0,000 0,05788343 0,06273887 ! appendage development GO:0048736 94 65 0,000 0,05788343 0,06270932 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 0,000 0,05788343 0,0626798 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 0,000 0,05788343 0,0626503 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 0,000 0,05788343 0,06262083 ! defense response to bacterium GO:0042742 73 65 0,000 0,05788343 0,06259139 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,05788343 0,06256198 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,05788343 0,06253259 ! activation of immune response GO:0002253 83 65 0,000 0,05788343 0,06250323 ! protein oligomerization GO:0051259 100 65 0,000 0,05788343 0,0624739 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,0587489 0,06337827 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,0587489 0,06334855 ! antigen processing and presentation GO:0019882 96 66 0,000 0,0587489 0,06331887 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,0587489 0,06328921 ! regulation of immune effector process GO:0002697 101 66 0,000 0,0587489 0,06325958 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,05961362 0,06416066 ! regulation of endopeptidase activity GO:0052548 99 67 0,000 0,05961362 0,06413065 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,05961362 0,06410067 ! acute inflammatory response GO:0002526 92 68 0,000 0,0604776 0,06499929 ! learning or memory GO:0007611 123 68 0,000 0,0604776 0,06496893 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,0604776 0,0649386 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,0604776 0,06490829 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,0604776 0,06487802 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,0604776 0,06484777 ! rhythmic process GO:0048511 105 68 0,000 0,0604776 0,06481756 ! inorganic anion transport GO:0015698 93 68 0,000 0,0604776 0,06478737 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,06134083 0,06568152 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,06134083 0,06565096 ! response to drug GO:0042493 108 69 0,000 0,06134083 0,06562043 ! positive regulation of ligase activity GO:0051351 99 69 0,000 0,06134083 0,06558992 ! response to metal ion GO:0010038 103 70 0,000 0,06220332 0,06648125 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,06220332 0,06645037 ! humoral immune response GO:0006959 86 70 0,000 0,06220332 0,06641952 ! eye development GO:0001654 111 70 0,000 0,06220332 0,0663887 ! amine transport GO:0015837 101 70 0,000 0,06220332 0,0663579 ! positive regulation of phosphorylation GO:0042327 102 70 0,000 0,06220332 0,06632714 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,06220332 0,06629641 ! regulation of catabolic process GO:0009894 106 70 0,000 0,06220332 0,0662657 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,06306507 0,06715262 ! muscle cell differentiation GO:0042692 104 71 0,000 0,06306507 0,06712155 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,06306507 0,0670905 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 0,000 0,06306507 0,06705948 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,06306507 0,06702849 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,06306507 0,06699753 ! regulation of peptidase activity GO:0052547 106 72 0,000 0,06392608 0,06788087 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 0,000 0,06392608 0,06784955 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 132 72 0,000 0,06392608 0,06781825 ! negative regulation of organelle organization GO:0010639 115 72 0,000 0,06392608 0,06778699 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,06392608 0,06775575 ! negative regulation of transport GO:0051051 116 73 0,000 0,06478634 0,06863592 ! regulation of blood pressure GO:0008217 107 73 0,000 0,06478634 0,06860432 ! tube morphogenesis GO:0035239 118 73 0,000 0,06478634 0,06857275 ! mitochondrion organization GO:0007005 104 73 0,000 0,06478634 0,0685412 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,06478634 0,06850969 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,06478634 0,06847821 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,06564586 0,06935484 ! response to oxygen levels GO:0070482 137 74 0,000 0,06564586 0,06932299 ! digestion GO:0007586 97 74 0,000 0,06564586 0,06929118 ! protein import into nucleus GO:0006606 118 74 0,000 0,06564586 0,06925939 ! cellular response to hormone stimulus GO:0032870 109 74 0,000 0,06564586 0,06922764 ! positive regulation of lymphocyte activation GO:0051251 108 74 0,000 0,06564586 0,06919591 ! blood coagulation GO:0007596 116 75 0,000 0,06650464 0,07006902 GO:0050817|coagulation, ! response to inorganic substance GO:0010035 115 75 0,000 0,06650464 0,07003694 ! response to nutrient GO:0007584 104 75 0,000 0,06650464 0,07000489 ! regulation of ligase activity GO:0051340 114 75 0,000 0,06650464 0,06997286 ! nuclear import GO:0051170 121 75 0,000 0,06650464 0,06994087 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,06650464 0,0699089 ! amine biosynthetic process GO:0009309 97 76 0,000 0,06736268 0,07077852 ! tRNA metabolic process GO:0006399 95 76 0,000 0,06736268 0,0707462 ! response to unfolded protein GO:0006986 99 76 0,000 0,06736268 0,07071391 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,06736268 0,07068165 ! regulation of protein transport GO:0051223 114 76 0,000 0,06736268 0,07064942 GO:0070201|regulation of establishment of protein localization, ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,06821999 0,07151594 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,06821999 0,07148336 ! regulation of DNA binding GO:0051101 119 77 0,000 0,06821999 0,0714508 ! gland development GO:0048732 148 77 0,000 0,06821999 0,07141828 ! sex differentiation GO:0007548 105 77 0,000 0,06821999 0,07138579 ! protein ubiquitination GO:0016567 125 77 0,000 0,06821999 0,07135333 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,06821999 0,07132089 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,06821999 0,07128849 ! positive regulation of protein modification process GO:0031401 107 78 0,000 0,06907655 0,0721508 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,06907655 0,07211805 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,06907655 0,07208533 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,06993237 0,07294533 ! cellular respiration GO:0045333 107 79 0,000 0,06993237 0,07291227 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,06993237 0,07287923 ! T cell activation GO:0042110 134 79 0,000 0,06993237 0,07284622 ! regulation of lyase activity GO:0051339 133 79 0,000 0,06993237 0,07281324 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,06993237 0,0727803 ! chromatin assembly GO:0031497 102 80 0,000 0,07078746 0,07363689 GO:0006334|nucleosome assembly, ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 0,000 0,07078746 0,0736036 GO:0010498|proteasomal protein catabolic process, ! protein localization in nucleus GO:0034504 133 80 0,000 0,07078746 0,07357034 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,07078746 0,07353711 ! forebrain development GO:0030900 131 80 0,000 0,07078746 0,07350391 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,07164181 0,07435747 ! hemostasis GO:0007599 125 81 0,000 0,07164181 0,07432393 ! mRNA transport GO:0051028 121 81 0,000 0,07164181 0,07429043 ! regulation of cell cycle process GO:0010564 122 81 0,000 0,07164181 0,07425695 ! response to protein stimulus GO:0051789 111 81 0,000 0,07164181 0,0742235 ! regulation of neurological system process GO:0031644 122 81 0,000 0,07164181 0,07419008 ! vitamin metabolic process GO:0006766 103 81 0,000 0,07164181 0,07415669 ! positive regulation of cell activation GO:0050867 120 81 0,000 0,07164181 0,07412333 GO:0002696|positive regulation of leukocyte activation, ! ossification GO:0001503 134 82 0,000 0,07249542 0,07497279 GO:0060348|bone development, ! detection of stimulus GO:0051606 108 82 0,000 0,07249542 0,07493909 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,0733483 0,07578665 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,0733483 0,07575262 ! regulation of cell adhesion GO:0030155 159 83 0,000 0,0733483 0,07571862 ! regulation of defense response GO:0031347 117 84 0,000 0,07420044 0,07656394 ! microtubule cytoskeleton organization GO:0000226 120 84 0,000 0,07420044 0,07652961 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,07420044 0,0764953 ! sterol metabolic process GO:0016125 120 84 0,000 0,07420044 0,07646103 ! regulation of DNA metabolic process GO:0051052 135 85 0,000 0,07505185 0,07730374 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,07505185 0,07726914 ! rRNA metabolic process GO:0016072 107 85 0,000 0,07505185 0,07723457 GO:0006364|rRNA processing, ! transcription initiation GO:0006352 118 85 0,000 0,07505185 0,07720003 ! anterior/posterior pattern formation GO:0009952 124 85 0,000 0,07505185 0,07716552 ! regulation of protein localization GO:0032880 132 85 0,000 0,07505185 0,07713104 ! regulation of membrane potential GO:0042391 128 85 0,000 0,07505185 0,07709659 ! negative regulation of multicellular organismal process GO:0051241 133 85 0,000 0,07505185 0,07706217 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,07590253 0,07790085 ! cell cycle arrest GO:0007050 150 86 0,000 0,07590253 0,07786611 ! interphase of mitotic cell cycle GO:0051329 156 86 0,000 0,07590253 0,07783139 ! nucleosome organization GO:0034728 114 87 0,000 0,07675247 0,07866786 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,07675247 0,07863282 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,07675247 0,07859781 ! skeletal muscle tissue development GO:0007519 123 87 0,000 0,07675247 0,07856283 GO:0060538|skeletal muscle organ development, ! female pregnancy GO:0007565 130 87 0,000 0,07675247 0,07852788 ! Wnt receptor signaling pathway GO:0016055 130 87 0,000 0,07675247 0,07849296 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,07760167 0,07932615 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,07760167 0,07929091 ! interphase GO:0051325 159 88 0,000 0,07760167 0,07925571 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,07760167 0,07922053 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,07760167 0,07918538 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 0,000 0,07760167 0,07915027 ! regulation of neurogenesis GO:0050767 153 89 0,000 0,07845015 0,0799802 ! reproductive developmental process GO:0003006 127 89 0,000 0,07845015 0,07994477 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,07845015 0,07990936 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,07845015 0,07987399 ! regulation of T cell activation GO:0050863 128 89 0,000 0,07845015 0,07983865 ! leukocyte differentiation GO:0002521 143 90 0,000 0,07929789 0,0806657 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,07929789 0,08063004 ! hormone metabolic process GO:0042445 121 90 0,000 0,07929789 0,08059441 ! RNA localization GO:0006403 135 91 0,000 0,0801449 0,08141929 ! ATP metabolic process GO:0046034 137 91 0,000 0,0801449 0,08138335 ! response to virus GO:0009615 122 91 0,000 0,0801449 0,08134743 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,08099118 0,08217015 ! glycerophospholipid metabolic process GO:0006650 130 92 0,000 0,08099118 0,08213392 ! cell fate commitment GO:0045165 141 92 0,000 0,08099118 0,08209772 ! positive regulation of immune response GO:0050778 121 92 0,000 0,08099118 0,08206155 ! DNA recombination GO:0006310 146 92 0,000 0,08099118 0,08202542 ! sulfur metabolic process GO:0006790 118 92 0,000 0,08099118 0,08198932 ! regulation of cytoskeleton organization GO:0051493 154 93 0,000 0,08183674 0,08280884 ! peptidyl-amino acid modification GO:0018193 147 93 0,000 0,08183674 0,08277242 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,08183674 0,08273604 ! electron transport chain GO:0022900 123 94 0,000 0,08268156 0,08355342 ! response to oxidative stress GO:0006979 141 94 0,000 0,08268156 0,08351673 ! regulation of binding GO:0051098 151 95 0,000 0,08352565 0,08433231 ! angiogenesis GO:0001525 149 95 0,000 0,08352565 0,0842953 ! carboxylic acid transport GO:0046942 147 95 0,000 0,08352565 0,08425833 GO:0015849|organic acid transport, ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,08436902 0,08507178 ! in utero embryonic development GO:0001701 147 96 0,000 0,08436902 0,0850345 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,08436902 0,08499726 ! regulation of cellular component biogenesis GO:0044087 158 96 0,000 0,08436902 0,08496004 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,08436902 0,08492286 ! protein maturation GO:0051604 129 96 0,000 0,08436902 0,08488571 ! response to light stimulus GO:0009416 153 96 0,000 0,08436902 0,0848486 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,08521165 0,08565857 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! calcium ion transport GO:0006816 167 99 0,000 0,08689475 0,08731233 ! extracellular structure organization GO:0043062 156 99 0,000 0,08689475 0,0872742 ! protein import GO:0017038 156 99 0,000 0,08689475 0,08723611 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 0,000 0,08689475 0,08719805 ! regulation of translation GO:0006417 151 100 0,000 0,08773521 0,08800304 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,08773521 0,08796468 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,08773521 0,08792635 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,08773521 0,08788806 ! divalent metal ion transport GO:0070838 171 100 0,000 0,08773521 0,08784979 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,08773521 0,08781157 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,08773521 0,08777337 ! protein localization in organelle GO:0033365 161 100 0,000 0,08773521 0,08773521