pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-b2/out-0.05-06-0.01-300-run-b2//th1-pval-1e-01-06-th2-pval-1e-02-02-th3-pval-1e-01-01-run-b2/go_data/1894-2-real-Ivshina_GPL96-GPL97-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 1,727E-06 4,156E-03 ! cellular response to unfolded protein GO:0034620 33 19 1,000 1,053E-05 0,01267243 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 1,847E-05 0,01480975 ! fat cell differentiation GO:0045444 50 27 1,000 2,16E-05 0,0129921 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 2,326E-05 0,01119171 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 1,000 6,353E-05 0,02547563 ! response to calcium ion GO:0051592 81 47 1,000 6,635E-05 0,02280373 ! positive regulation of cell cycle GO:0045787 89 48 1,000 6,922E-05 0,02081803 ! response to UV GO:0009411 104 53 1,000 8,451E-05 0,02259117 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 1,000 9,782E-05 0,02353607 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 1,394E-04 0,0304949 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 1,436E-04 0,02878427 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 1,000 1,564E-04 0,02893695 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 1,564E-04 0,02687003 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 1,000 1,564E-04 0,02507869 ! positive regulation of ligase activity GO:0051351 124 77 1,000 1,789E-04 0,02689683 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 1,000 1,883E-04 0,02664858 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 1,883E-04 0,0251681 ! response to metal ion GO:0010038 140 80 1,000 1,931E-04 0,02445158 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 1,98E-04 0,02381391 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of ligase activity GO:0051340 142 84 1,000 2,129E-04 0,02439218 ! response to unfolded protein GO:0006986 131 85 1,000 2,18E-04 0,02384133 ! response to inorganic substance GO:0010035 153 86 1,000 2,232E-04 0,02334461 ! positive regulation of protein modification process GO:0031401 136 88 1,000 2,337E-04 0,02342461 ! response to protein stimulus GO:0051789 149 91 1,000 2,499E-04 0,02404653 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 2,61E-04 0,02414852 GO:0010498|proteasomal protein catabolic process, ! interphase of mitotic cell cycle GO:0051329 209 95 1,000 2,723E-04 0,02426416 ! regulation of Rho protein signal transduction GO:0035023 213 95 1,000 2,723E-04 0,02339758 ! interphase GO:0051325 213 98 1,000 2,897E-04 0,02403832 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 1,328E-03 0,10646841 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 1,328E-03 0,10303394 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 1,328E-03 0,09981413 ! positive regulation of helicase activity GO:0051096 11 5 0,000 1,328E-03 0,09678946 ! neuron fate determination GO:0048664 7 5 0,000 1,328E-03 0,09394271 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 1,328E-03 0,09125863 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 1,328E-03 0,08872367 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 1,328E-03 0,08632573 ! polyol transport GO:0015791 12 5 0,000 1,328E-03 0,08405401 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 1,328E-03 0,08189877 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 1,328E-03 0,0798513 ! response to superoxide GO:0000303 10 5 0,000 1,328E-03 0,07790371 ! negative regulation of bone resorption GO:0045779 10 5 0,000 1,328E-03 0,07604886 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 1,328E-03 0,07428028 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 1,328E-03 0,0725921 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 1,328E-03 0,07097894 ! female meiosis GO:0007143 7 5 0,000 1,328E-03 0,06943592 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 1,328E-03 0,06795856 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 1,328E-03 0,06654275 ! cobalt ion transport GO:0006824 11 5 0,000 1,328E-03 0,06518474 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 1,328E-03 0,06388104 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 1,328E-03 0,06262847 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 1,328E-03 0,06142408 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 1,328E-03 0,06026514 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 1,328E-03 0,05914911 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 1,328E-03 0,05807368 ! embryonic camera-type eye development GO:0031076 10 5 0,000 1,328E-03 0,05703665 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 1,328E-03 0,056036 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 1,328E-03 0,05506987 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 1,328E-03 0,05413648 ! adaptation of signaling pathway GO:0022401 7 5 0,000 1,328E-03 0,0532342 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 1,328E-03 0,05236151 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 1,328E-03 0,05151697 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 1,328E-03 0,05069924 ! negative chemotaxis GO:0050919 14 5 0,000 1,328E-03 0,04990707 ! positive regulation of histone modification GO:0031058 5 5 0,000 1,328E-03 0,04913926 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 1,328E-03 0,04839473 ! sensory perception of bitter taste GO:0050913 7 5 0,000 1,328E-03 0,04767242 ! behavioral response to pain GO:0048266 9 5 0,000 1,328E-03 0,04697136 ! clathrin coat assembly GO:0048268 14 5 0,000 1,328E-03 0,04629061 ! Notch receptor processing GO:0007220 8 5 0,000 1,328E-03 0,04562932 ! regulation of dopamine uptake GO:0051584 9 5 0,000 1,328E-03 0,04498665 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 1,328E-03 0,04436184 ! micturition GO:0060073 9 5 0,000 1,328E-03 0,04375414 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 1,328E-03 0,04316287 ! copulation GO:0007620 9 5 0,000 1,328E-03 0,04258736 ! glial cell fate commitment GO:0021781 13 5 0,000 1,328E-03 0,042027 ! protein maturation by protein folding GO:0022417 13 5 0,000 1,328E-03 0,0414812 ! spermidine metabolic process GO:0008216 7 5 0,000 1,328E-03 0,04094939 ! regulation of potassium ion transport GO:0043266 10 5 0,000 1,328E-03 0,04043104 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 1,328E-03 0,03992565 ! apoptotic cell clearance GO:0043277 20 5 0,000 1,328E-03 0,03943274 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 1,328E-03 0,03895186 ! lipoprotein particle clearance GO:0034381 10 5 0,000 1,328E-03 0,03848256 ! grooming behavior GO:0007625 6 5 0,000 1,328E-03 0,03802443 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 1,328E-03 0,03757708 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 1,328E-03 0,03714014 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 1,328E-03 0,03671324 ! response to protozoan GO:0001562 10 5 0,000 1,328E-03 0,03629605 ! positive regulation of glycolysis GO:0045821 14 5 0,000 1,328E-03 0,03588823 ! lymph vessel development GO:0001945 10 5 0,000 1,328E-03 0,03548947 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 1,328E-03 0,03509947 ! endochondral ossification GO:0001958 16 5 0,000 1,328E-03 0,03471796 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 1,328E-03 0,03434465 ! parathyroid gland development GO:0060017 13 5 0,000 1,328E-03 0,03397928 ! anagen GO:0042640 6 5 0,000 1,328E-03 0,0336216 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 1,328E-03 0,03327138 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 1,328E-03 0,03292837 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 1,328E-03 0,03259237 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 1,328E-03 0,03226315 ! dorsal spinal cord development GO:0021516 7 5 0,000 1,328E-03 0,03194052 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 1,328E-03 0,03162428 ! sphingoid catabolic process GO:0046521 6 5 0,000 1,328E-03 0,03131424 ! skeletal myofibril assembly GO:0014866 10 5 0,000 1,328E-03 0,03101022 ! smooth muscle tissue development GO:0048745 28 5 0,000 1,328E-03 0,03071204 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 1,328E-03 0,03041954 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 1,328E-03 0,03013257 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 1,328E-03 0,02985096 ! cardiac muscle fiber development GO:0048739 10 5 0,000 1,328E-03 0,02957456 ! transepithelial chloride transport GO:0030321 9 5 0,000 1,328E-03 0,02930323 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 1,328E-03 0,02903684 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 1,328E-03 0,02877524 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 1,328E-03 0,02851832 ! neutrophil mediated immunity GO:0002446 7 5 0,000 1,328E-03 0,02826595 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 1,328E-03 0,028018 ! histidine catabolic process GO:0006548 6 5 0,000 1,328E-03 0,02777437 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 1,328E-03 0,02753493 ! microvillus organization GO:0032528 7 5 0,000 1,328E-03 0,02729959 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 1,328E-03 0,02706824 ! L-serine biosynthetic process GO:0006564 6 5 0,000 1,328E-03 0,02684077 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 1,328E-03 0,0266171 ! tryptophan metabolic process GO:0006568 9 5 0,000 1,328E-03 0,02639713 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 1,328E-03 0,02618076 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 1,328E-03 0,0259679 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 1,328E-03 0,02575849 ! polyol catabolic process GO:0046174 7 5 0,000 1,328E-03 0,02555242 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 1,328E-03 0,02534962 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 1,328E-03 0,02515002 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 1,328E-03 0,02495353 ! muscle cell migration GO:0014812 8 5 0,000 1,328E-03 0,02476009 ! mitochondrial fission GO:0000266 8 5 0,000 1,328E-03 0,02456963 ! sister chromatid cohesion GO:0007062 12 5 0,000 1,328E-03 0,02438208 ! mRNA transcription GO:0009299 9 5 0,000 1,328E-03 0,02419737 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 1,328E-03 0,02401543 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 1,328E-03 0,02383621 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 1,328E-03 0,02365965 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 1,328E-03 0,02348568 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 1,328E-03 0,02331425 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 1,328E-03 0,02314531 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 1,328E-03 0,02297879 ! response to food GO:0032094 6 5 0,000 1,328E-03 0,02281466 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 1,328E-03 0,02265285 ! positive regulation of transporter activity GO:0032411 8 5 0,000 1,328E-03 0,02249333 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 1,328E-03 0,02233603 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 1,328E-03 0,02218092 ! paraxial mesoderm development GO:0048339 14 5 0,000 1,328E-03 0,02202795 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 1,328E-03 0,02187707 ! forebrain neuron development GO:0021884 13 5 0,000 1,328E-03 0,02172825 ! lipoprotein catabolic process GO:0042159 11 5 0,000 1,328E-03 0,02158143 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 1,328E-03 0,02143659 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 1,328E-03 0,02129368 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 1,328E-03 0,02115266 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 1,328E-03 0,0210135 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 1,328E-03 0,02087616 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 1,328E-03 0,0207406 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 1,328E-03 0,02060679 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 1,328E-03 0,02047469 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 1,328E-03 0,02034428 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 1,328E-03 0,02021552 ! basic amino acid transport GO:0015802 11 5 0,000 1,328E-03 0,02008838 ! cellular glucose homeostasis GO:0001678 5 5 0,000 1,328E-03 0,01996283 ! early endosome to late endosome transport GO:0045022 12 5 0,000 1,328E-03 0,01983883 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 1,328E-03 0,01971637 ! depyrimidination GO:0045008 10 5 0,000 1,328E-03 0,01959541 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 1,328E-03 0,01947593 ! regulation of centrosome cycle GO:0046605 7 5 0,000 1,328E-03 0,01935789 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 1,328E-03 0,01924128 ! zinc ion homeostasis GO:0055069 8 5 0,000 1,328E-03 0,01912606 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 1,328E-03 0,01901222 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 1,328E-03 0,01889972 ! forebrain morphogenesis GO:0048853 13 5 0,000 1,328E-03 0,01878854 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 1,328E-03 0,01867867 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 1,328E-03 0,01857007 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 1,328E-03 0,01846273 ! peptidyl-arginine modification GO:0018195 9 5 0,000 1,328E-03 0,01835662 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 1,328E-03 0,01825173 ! positive regulation of organ growth GO:0046622 6 5 0,000 1,328E-03 0,01814802 ! response to arsenic GO:0046685 10 5 0,000 1,328E-03 0,01804549 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 1,328E-03 0,01794411 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 1,328E-03 0,01784387 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 1,328E-03 0,01774473 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 1,328E-03 0,0176467 ! response to cadmium ion GO:0046686 7 5 0,000 1,328E-03 0,01754974 ! bile acid biosynthetic process GO:0006699 6 5 0,000 1,328E-03 0,01745384 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 1,328E-03 0,01735898 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 1,328E-03 0,01726515 ! decidualization GO:0046697 11 5 0,000 1,328E-03 0,01717232 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 1,328E-03 0,01708049 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 1,328E-03 0,01698964 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 1,328E-03 0,01689975 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 1,328E-03 0,0168108 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 1,328E-03 0,01672279 ! base conversion or substitution editing GO:0016553 5 5 0,000 1,328E-03 0,01663569 ! neural tube patterning GO:0021532 7 5 0,000 1,328E-03 0,01654949 ! embryonic cleavage GO:0040016 6 5 0,000 1,328E-03 0,01646419 ! peroxisome fission GO:0016559 5 5 0,000 1,328E-03 0,01637975 ! histone demethylation GO:0016577 10 5 0,000 1,328E-03 0,01629618 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 1,328E-03 0,01621346 ! mitotic recombination GO:0006312 9 5 0,000 1,328E-03 0,01613158 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 1,328E-03 0,01605051 ! metaphase plate congression GO:0051310 7 5 0,000 1,328E-03 0,01597026 ! regulation of sterol transport GO:0032371 7 5 0,000 1,328E-03 0,01589081 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 1,328E-03 0,01581214 ! enteric nervous system development GO:0048484 8 5 0,000 1,328E-03 0,01573425 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 1,328E-03 0,01565712 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 1,328E-03 0,01558074 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 1,328E-03 0,01550511 ! muscle cell proliferation GO:0033002 11 5 0,000 1,328E-03 0,0154302 ! skeletal muscle regeneration GO:0043403 8 5 0,000 1,328E-03 0,01535602 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 1,328E-03 0,01528255 ! plasminogen activation GO:0031639 5 5 0,000 1,328E-03 0,01520977 ! B cell homeostasis GO:0001782 13 5 0,000 1,328E-03 0,01513769 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 1,328E-03 0,01506628 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 1,328E-03 0,01499555 ! metaphase GO:0051323 8 5 0,000 1,328E-03 0,01492548 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 1,328E-03 0,01485606 ! cellular response to nutrient GO:0031670 8 5 0,000 1,328E-03 0,01478728 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 1,328E-03 0,01471913 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 1,328E-03 0,01465162 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 1,328E-03 0,01458471 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 1,328E-03 0,01451842 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 1,328E-03 0,01445272 ! response to redox state GO:0051775 5 5 0,000 1,328E-03 0,01438762 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 1,328E-03 0,0143231 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 1,328E-03 0,01425916 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 1,328E-03 0,01419579 ! regulation of telomerase activity GO:0051972 6 5 0,000 1,328E-03 0,01413297 ! galactolipid metabolic process GO:0019374 7 5 0,000 1,328E-03 0,01407071 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 1,328E-03 0,014009 ! porphyrin catabolic process GO:0006787 12 5 0,000 1,328E-03 0,01394783 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 1,328E-03 0,01388718 ! striatum development GO:0021756 9 5 0,000 1,328E-03 0,01382707 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 1,328E-03 0,01376747 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 1,328E-03 0,01370838 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 1,328E-03 0,0136498 ! glial cell migration GO:0008347 11 5 0,000 1,328E-03 0,01359171 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 1,328E-03 0,01353412 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 1,328E-03 0,01347701 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 1,328E-03 0,01342039 ! somatic stem cell maintenance GO:0035019 15 5 0,000 1,328E-03 0,01336424 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 1,328E-03 0,01330855 ! negative regulation of lipase activity GO:0060192 8 5 0,000 1,328E-03 0,01325333 ! neuroprotection GO:0043526 6 5 0,000 1,328E-03 0,01319856 ! neural plate development GO:0001840 8 5 0,000 1,328E-03 0,01314425 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 1,328E-03 0,01309038 ! regulation of sensory perception GO:0051931 7 5 0,000 1,328E-03 0,01303695 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 1,328E-03 0,01298395 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 1,328E-03 0,01293139 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 1,328E-03 0,01287924 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 1,328E-03 0,01282752 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 1,328E-03 0,01277621 ! sequestering of calcium ion GO:0051208 7 5 0,000 1,328E-03 0,01272531 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 1,328E-03 0,01267481 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 1,328E-03 0,01262471 ! spindle assembly GO:0051225 6 5 0,000 1,328E-03 0,01257501 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 1,328E-03 0,01252569 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 1,328E-03 0,01247677 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 1,328E-03 0,01242822 ! drug metabolic process GO:0017144 6 5 0,000 1,328E-03 0,01238005 ! stem cell division GO:0017145 11 5 0,000 1,328E-03 0,01233225 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 1,328E-03 0,01228482 ! organ regeneration GO:0031100 7 5 0,000 1,328E-03 0,01223775 ! carnitine metabolic process GO:0009437 7 5 0,000 1,328E-03 0,01219104 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 1,328E-03 0,01214469 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 1,328E-03 0,01209868 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 1,593E-03 0,01446195 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 1,593E-03 0,01440758 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 1,593E-03 0,01435362 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 1,593E-03 0,01430006 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 1,593E-03 0,0142469 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 1,593E-03 0,01419414 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 1,593E-03 0,01414176 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 1,593E-03 0,01408977 ! sleep GO:0030431 13 6 0,000 1,593E-03 0,01403816 ! response to oxygen radical GO:0000305 11 6 0,000 1,593E-03 0,01398692 ! positive regulation of axon extension GO:0045773 11 6 0,000 1,593E-03 0,01393606 ! myoblast cell fate commitment GO:0048625 16 6 0,000 1,593E-03 0,01388557 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 1,593E-03 0,01383544 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 1,593E-03 0,01378567 ! regulation of interferon-beta production GO:0032648 8 6 0,000 1,593E-03 0,01373626 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 1,593E-03 0,0136872 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 1,593E-03 0,0136385 ! forebrain regionalization GO:0021871 8 6 0,000 1,593E-03 0,01359013 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 1,593E-03 0,01354211 ! male meiosis GO:0007140 7 6 0,000 1,593E-03 0,01349443 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 1,593E-03 0,01344708 ! response to zinc ion GO:0010043 9 6 0,000 1,593E-03 0,01340006 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 1,593E-03 0,01335337 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 1,593E-03 0,013307 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 1,593E-03 0,01326096 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 1,593E-03 0,01321523 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 1,593E-03 0,01316982 ! malate metabolic process GO:0006108 11 6 0,000 1,593E-03 0,01312472 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 1,593E-03 0,01307992 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 1,593E-03 0,01303543 ! protein refolding GO:0042026 15 6 0,000 1,593E-03 0,01299124 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 1,593E-03 0,01294736 ! opsonization GO:0008228 8 6 0,000 1,593E-03 0,01290376 ! mating behavior GO:0007617 7 6 0,000 1,593E-03 0,01286046 ! neuron remodeling GO:0016322 15 6 0,000 1,593E-03 0,01281745 ! erythrocyte maturation GO:0043249 7 6 0,000 1,593E-03 0,01277472 ! embryonic hemopoiesis GO:0035162 14 6 0,000 1,593E-03 0,01273228 ! equilibrioception GO:0050957 14 6 0,000 1,593E-03 0,01269012 ! protein amino acid dealkylation GO:0008214 12 6 0,000 1,593E-03 0,01264824 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 1,593E-03 0,01260664 ! photoreceptor cell development GO:0042461 10 6 0,000 1,593E-03 0,0125653 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 1,593E-03 0,01252424 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 1,593E-03 0,01248344 ! response to interferon-gamma GO:0034341 15 6 0,000 1,593E-03 0,01244291 ! toxin metabolic process GO:0009404 11 6 0,000 1,593E-03 0,01240264 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 1,593E-03 0,01236264 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 1,593E-03 0,01232288 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 1,593E-03 0,01228339 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 1,593E-03 0,01224414 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 1,593E-03 0,01220515 ! cGMP-mediated signaling GO:0019934 13 6 0,000 1,593E-03 0,0121664 ! activation of MAPKKK activity GO:0000185 12 6 0,000 1,593E-03 0,0121279 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 1,593E-03 0,01208964 ! thymic T cell selection GO:0045061 12 6 0,000 1,593E-03 0,01205163 ! protein lipoylation GO:0009249 10 6 0,000 1,593E-03 0,01201385 ! cysteine metabolic process GO:0006534 10 6 0,000 1,593E-03 0,0119763 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 1,593E-03 0,01193899 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 1,593E-03 0,01190192 ! glutamate catabolic process GO:0006538 10 6 0,000 1,593E-03 0,01186507 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 1,593E-03 0,01182845 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 1,593E-03 0,01179205 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 1,593E-03 0,01175588 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 1,593E-03 0,01171993 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 1,593E-03 0,0116842 ! hyperosmotic response GO:0006972 9 6 0,000 1,593E-03 0,01164868 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 1,593E-03 0,01161339 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 1,593E-03 0,0115783 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 1,593E-03 0,01154343 ! urea metabolic process GO:0019627 7 6 0,000 1,593E-03 0,01150876 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 1,593E-03 0,0114743 ! neutrophil activation GO:0042119 8 6 0,000 1,593E-03 0,01144005 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 1,593E-03 0,011406 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 1,593E-03 0,01137216 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 1,593E-03 0,01133851 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 1,593E-03 0,01130507 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 1,593E-03 0,01127182 ! neuron apoptosis GO:0051402 9 6 0,000 1,593E-03 0,01123876 ! nucleoside salvage GO:0043174 9 6 0,000 1,593E-03 0,0112059 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 1,593E-03 0,01117323 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 1,593E-03 0,01114075 ! T cell mediated immunity GO:0002456 16 6 0,000 1,593E-03 0,01110846 ! negative regulation of platelet activation GO:0010544 9 6 0,000 1,593E-03 0,01107635 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 1,593E-03 0,01104443 ! carnitine transport GO:0015879 10 6 0,000 1,593E-03 0,01101269 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 1,593E-03 0,01098114 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 1,593E-03 0,01094976 ! positive regulation of exocytosis GO:0045921 8 6 0,000 1,593E-03 0,01091857 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 1,593E-03 0,01088755 ! 5S class rRNA transcription GO:0042791 11 6 0,000 1,593E-03 0,01085671 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 1,593E-03 0,01082604 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 1,593E-03 0,01079554 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 1,593E-03 0,01076522 ! sodium ion homeostasis GO:0055078 11 6 0,000 1,593E-03 0,01073506 ! establishment of spindle localization GO:0051293 12 6 0,000 1,593E-03 0,01070508 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 1,593E-03 0,01067526 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 1,593E-03 0,0106456 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 1,593E-03 0,01061611 ! neural nucleus development GO:0048857 14 6 0,000 1,593E-03 0,01058679 ! response to UV-C GO:0010225 11 6 0,000 1,593E-03 0,01055762 ! astrocyte development GO:0014002 15 6 0,000 1,593E-03 0,01052862 ! protein targeting to lysosome GO:0006622 10 6 0,000 1,593E-03 0,01049977 ! purine base biosynthetic process GO:0009113 17 6 0,000 1,593E-03 0,01047109 ! interaction with symbiont GO:0051702 13 6 0,000 1,593E-03 0,01044255 ! regulation of dendrite development GO:0050773 16 6 0,000 1,593E-03 0,01041418 ! skeletal muscle contraction GO:0003009 6 6 0,000 1,593E-03 0,01038595 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 1,593E-03 0,01035788 ! response to copper ion GO:0046688 10 6 0,000 1,593E-03 0,01032997 ! response to exogenous dsRNA GO:0043330 10 6 0,000 1,593E-03 0,0103022 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 1,593E-03 0,01027458 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 1,593E-03 0,0102471 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 1,593E-03 0,01021978 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 1,593E-03 0,0101926 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 1,593E-03 0,01016556 ! regulation of dopamine secretion GO:0014059 14 6 0,000 1,593E-03 0,01013867 ! nucleoside catabolic process GO:0009164 7 6 0,000 1,593E-03 0,01011192 ! hair follicle maturation GO:0048820 7 6 0,000 1,593E-03 0,01008531 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 1,593E-03 0,01005884 ! Schwann cell development GO:0014044 15 6 0,000 1,593E-03 0,01003251 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 1,593E-03 0,01000631 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 1,593E-03 9,98E-03 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 1,593E-03 9,954E-03 ! subpallium development GO:0021544 10 6 0,000 1,593E-03 9,929E-03 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 1,593E-03 9,903E-03 ! histone ubiquitination GO:0016574 8 6 0,000 1,593E-03 9,877E-03 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 1,593E-03 9,852E-03 ! maintenance of organ identity GO:0048496 9 6 0,000 1,593E-03 9,827E-03 ! G2 phase GO:0051319 16 6 0,000 1,593E-03 9,802E-03 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 1,593E-03 9,777E-03 ! establishment of planar polarity GO:0001736 7 6 0,000 1,593E-03 9,752E-03 ! regulation of mast cell activation GO:0033003 12 6 0,000 1,593E-03 9,727E-03 ! membrane to membrane docking GO:0022614 14 6 0,000 1,593E-03 9,702E-03 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 1,593E-03 9,678E-03 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 1,593E-03 9,653E-03 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 1,593E-03 9,629E-03 ! receptor internalization GO:0031623 10 6 0,000 1,593E-03 9,605E-03 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 1,593E-03 9,581E-03 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 1,593E-03 9,557E-03 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 1,593E-03 9,533E-03 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 1,593E-03 9,51E-03 ! protein deubiquitination GO:0016579 14 6 0,000 1,593E-03 9,486E-03 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 1,593E-03 9,463E-03 ! protein destabilization GO:0031648 9 6 0,000 1,593E-03 9,439E-03 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 1,593E-03 9,416E-03 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 1,593E-03 9,393E-03 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 1,593E-03 9,37E-03 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 1,593E-03 9,347E-03 ! progesterone metabolic process GO:0042448 10 6 0,000 1,593E-03 9,325E-03 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 1,593E-03 9,302E-03 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 1,593E-03 9,279E-03 ! negative regulation of axon extension GO:0030517 21 6 0,000 1,593E-03 9,257E-03 ! removal of superoxide radicals GO:0019430 11 6 0,000 1,593E-03 9,235E-03 ! triglyceride catabolic process GO:0019433 10 6 0,000 1,593E-03 9,213E-03 ! determination of adult lifespan GO:0008340 15 6 0,000 1,593E-03 9,19E-03 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 1,593E-03 9,168E-03 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 1,593E-03 9,147E-03 ! cerebellar cortex formation GO:0021697 8 6 0,000 1,593E-03 9,125E-03 ! catecholamine transport GO:0051937 9 6 0,000 1,593E-03 9,103E-03 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 1,593E-03 9,082E-03 ! sensory cilium assembly GO:0035058 10 6 0,000 1,593E-03 9,06E-03 ! organ or tissue specific immune response GO:0002251 7 6 0,000 1,593E-03 9,039E-03 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 1,593E-03 9,017E-03 ! maternal placenta development GO:0001893 12 6 0,000 1,593E-03 8,996E-03 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 1,593E-03 8,975E-03 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 1,593E-03 8,954E-03 ! negative regulation of B cell activation GO:0050869 13 6 0,000 1,593E-03 8,933E-03 ! protein amino acid prenylation GO:0018346 16 6 0,000 1,593E-03 8,913E-03 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 1,593E-03 8,892E-03 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 1,593E-03 8,871E-03 ! positive regulation of coagulation GO:0050820 12 6 0,000 1,593E-03 8,851E-03 ! tRNA transcription GO:0009304 14 7 0,000 1,858E-03 0,010301 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 1,858E-03 0,01027732 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 1,858E-03 0,01025375 ! behavioral response to cocaine GO:0048148 14 7 0,000 1,858E-03 0,01023028 ! regulation of helicase activity GO:0051095 15 7 0,000 1,858E-03 0,01020693 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 1,858E-03 0,01018368 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 1,858E-03 0,01016053 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 1,858E-03 0,01013749 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 1,858E-03 0,01011456 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 1,858E-03 0,01009172 ! prostate gland development GO:0030850 13 7 0,000 1,858E-03 0,010069 ! nucleotide-sugar transport GO:0015780 12 7 0,000 1,858E-03 0,01004637 ! synaptonemal complex assembly GO:0007130 10 7 0,000 1,858E-03 0,01002384 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 1,858E-03 0,01000142 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 1,858E-03 9,979E-03 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 1,858E-03 9,957E-03 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 1,858E-03 9,935E-03 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 1,858E-03 9,913E-03 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 1,858E-03 9,891E-03 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 1,858E-03 9,869E-03 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 1,858E-03 9,847E-03 ! SMAD protein complex assembly GO:0007183 12 7 0,000 1,858E-03 9,826E-03 ! glycolipid transport GO:0046836 10 7 0,000 1,858E-03 9,804E-03 ! protein amino acid sulfation GO:0006477 10 7 0,000 1,858E-03 9,783E-03 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 1,858E-03 9,761E-03 ! neuron adhesion GO:0007158 12 7 0,000 1,858E-03 9,74E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 1,858E-03 9,719E-03 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 1,858E-03 9,698E-03 ! actin-myosin filament sliding GO:0033275 11 7 0,000 1,858E-03 9,677E-03 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 1,858E-03 9,656E-03 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 1,858E-03 9,635E-03 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 1,858E-03 9,614E-03 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 1,858E-03 9,594E-03 ! mRNA stabilization GO:0048255 18 7 0,000 1,858E-03 9,573E-03 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 1,858E-03 9,553E-03 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 1,858E-03 9,532E-03 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 1,858E-03 9,512E-03 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 1,858E-03 9,492E-03 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 1,858E-03 9,472E-03 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 1,858E-03 9,452E-03 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 1,858E-03 9,432E-03 ! lipoprotein transport GO:0042953 14 7 0,000 1,858E-03 9,412E-03 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 1,858E-03 9,392E-03 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 1,858E-03 9,372E-03 ! rhythmic behavior GO:0007622 15 7 0,000 1,858E-03 9,353E-03 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 1,858E-03 9,333E-03 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 1,858E-03 9,314E-03 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 1,858E-03 9,294E-03 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 1,858E-03 9,275E-03 ! regulation of odontogenesis GO:0042481 13 7 0,000 1,858E-03 9,256E-03 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 1,858E-03 9,237E-03 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 1,858E-03 9,218E-03 ! mechanosensory behavior GO:0007638 14 7 0,000 1,858E-03 9,199E-03 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 1,858E-03 9,18E-03 ! positive regulation of isotype switching GO:0045830 15 7 0,000 1,858E-03 9,161E-03 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 1,858E-03 9,142E-03 ! protein-cofactor linkage GO:0018065 13 7 0,000 1,858E-03 9,124E-03 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 1,858E-03 9,105E-03 ! spinal cord patterning GO:0021511 13 7 0,000 1,858E-03 9,087E-03 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 1,858E-03 9,068E-03 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 1,858E-03 9,05E-03 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 1,858E-03 9,032E-03 ! adrenal gland development GO:0030325 17 7 0,000 1,858E-03 9,013E-03 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 1,858E-03 8,995E-03 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 1,858E-03 8,977E-03 ! ovulation GO:0030728 9 7 0,000 1,858E-03 8,959E-03 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 1,858E-03 8,941E-03 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 1,858E-03 8,923E-03 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 1,858E-03 8,906E-03 ! microtubule nucleation GO:0007020 20 7 0,000 1,858E-03 8,888E-03 ! proline biosynthetic process GO:0006561 10 7 0,000 1,858E-03 8,87E-03 ! thyroid hormone generation GO:0006590 13 7 0,000 1,858E-03 8,853E-03 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 1,858E-03 8,835E-03 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 1,858E-03 8,818E-03 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 1,858E-03 8,8E-03 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 1,858E-03 8,783E-03 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 1,858E-03 8,766E-03 ! galactose metabolic process GO:0006012 13 7 0,000 1,858E-03 8,749E-03 ! vesicle fusion GO:0006906 17 7 0,000 1,858E-03 8,732E-03 ! response to dietary excess GO:0002021 8 7 0,000 1,858E-03 8,715E-03 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 1,858E-03 8,698E-03 ! intracellular pH reduction GO:0051452 11 7 0,000 1,858E-03 8,681E-03 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 1,858E-03 8,664E-03 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 1,858E-03 8,647E-03 ! organ growth GO:0035265 15 7 0,000 1,858E-03 8,631E-03 ! purine salvage GO:0043101 10 7 0,000 1,858E-03 8,614E-03 ! nucleoside transport GO:0015858 8 7 0,000 1,858E-03 8,597E-03 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 1,858E-03 8,581E-03 ! parturition GO:0007567 14 7 0,000 1,858E-03 8,564E-03 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 1,858E-03 8,548E-03 ! rRNA modification GO:0000154 14 7 0,000 1,858E-03 8,532E-03 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 1,858E-03 8,515E-03 ! spindle checkpoint GO:0031577 15 7 0,000 1,858E-03 8,499E-03 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 1,858E-03 8,483E-03 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 1,858E-03 8,467E-03 ! macrophage differentiation GO:0030225 11 7 0,000 1,858E-03 8,451E-03 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 1,858E-03 8,435E-03 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 1,858E-03 8,419E-03 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 1,858E-03 8,403E-03 ! hyaluronan metabolic process GO:0030212 8 7 0,000 1,858E-03 8,388E-03 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 1,858E-03 8,372E-03 ! anterograde axon cargo transport GO:0008089 18 7 0,000 1,858E-03 8,356E-03 ! fibrinolysis GO:0042730 10 7 0,000 1,858E-03 8,341E-03 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 1,858E-03 8,325E-03 ! eating behavior GO:0042755 7 7 0,000 1,858E-03 8,31E-03 ! B cell lineage commitment GO:0002326 21 7 0,000 1,858E-03 8,294E-03 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 1,858E-03 8,279E-03 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 1,858E-03 8,264E-03 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 1,858E-03 8,248E-03 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 1,858E-03 8,233E-03 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 1,858E-03 8,218E-03 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 1,858E-03 8,203E-03 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 1,858E-03 8,188E-03 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 1,858E-03 8,173E-03 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 1,858E-03 8,158E-03 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 1,858E-03 8,143E-03 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 1,858E-03 8,128E-03 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 1,858E-03 8,114E-03 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 1,858E-03 8,099E-03 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 1,858E-03 8,084E-03 ! regulation of meiosis GO:0040020 12 7 0,000 1,858E-03 8,07E-03 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 1,858E-03 8,055E-03 ! T cell lineage commitment GO:0002360 16 7 0,000 1,858E-03 8,041E-03 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 1,858E-03 8,026E-03 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 1,858E-03 8,012E-03 ! oxygen homeostasis GO:0032364 12 7 0,000 1,858E-03 7,998E-03 ! transcription termination GO:0006353 13 7 0,000 1,858E-03 7,983E-03 ! response to tumor cell GO:0002347 13 7 0,000 1,858E-03 7,969E-03 ! regulation of respiratory burst GO:0060263 11 7 0,000 1,858E-03 7,955E-03 ! coenzyme A metabolic process GO:0015936 12 7 0,000 1,858E-03 7,941E-03 ! anaphase GO:0051322 17 7 0,000 1,858E-03 7,927E-03 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 1,858E-03 7,913E-03 ! axonal fasciculation GO:0007413 18 7 0,000 1,858E-03 7,899E-03 ! negative regulation of nuclear division GO:0051784 14 7 0,000 1,858E-03 7,885E-03 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 1,858E-03 7,871E-03 ! peptidyl-threonine modification GO:0018210 25 7 0,000 1,858E-03 7,857E-03 ! diuresis GO:0030146 12 7 0,000 1,858E-03 7,843E-03 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 1,858E-03 7,829E-03 ! thiamin metabolic process GO:0006772 7 7 0,000 1,858E-03 7,816E-03 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 1,858E-03 7,802E-03 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 1,858E-03 7,789E-03 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 1,858E-03 7,775E-03 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 1,858E-03 7,762E-03 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 1,858E-03 7,748E-03 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 1,858E-03 7,735E-03 ! melanin biosynthetic process GO:0042438 8 7 0,000 1,858E-03 7,721E-03 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 1,858E-03 7,708E-03 ! dopamine biosynthetic process GO:0042416 18 7 0,000 1,858E-03 7,695E-03 ! glycolipid catabolic process GO:0019377 15 7 0,000 1,858E-03 7,682E-03 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 1,858E-03 7,668E-03 ! lymph node development GO:0048535 10 7 0,000 1,858E-03 7,655E-03 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 1,858E-03 7,642E-03 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 1,858E-03 7,629E-03 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 1,858E-03 7,616E-03 ! endosome to lysosome transport GO:0008333 11 7 0,000 1,858E-03 7,603E-03 ! protein modification by small protein removal GO:0070646 16 7 0,000 1,858E-03 7,59E-03 ! adult feeding behavior GO:0008343 9 7 0,000 1,858E-03 7,577E-03 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 1,858E-03 7,565E-03 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 1,858E-03 7,552E-03 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 1,858E-03 7,539E-03 ! muscle adaptation GO:0043500 14 7 0,000 1,858E-03 7,526E-03 ! embryonic heart tube development GO:0035050 10 7 0,000 1,858E-03 7,514E-03 ! retina homeostasis GO:0001895 12 7 0,000 1,858E-03 7,501E-03 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 1,858E-03 7,488E-03 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 1,858E-03 7,476E-03 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 1,858E-03 7,463E-03 ! protein prenylation GO:0018342 18 7 0,000 1,858E-03 7,451E-03 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 1,858E-03 7,439E-03 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 1,858E-03 7,426E-03 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 1,858E-03 7,414E-03 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 2,123E-03 8,458E-03 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 2,123E-03 8,444E-03 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 2,123E-03 8,43E-03 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 2,123E-03 8,416E-03 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 2,123E-03 8,402E-03 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 2,123E-03 8,389E-03 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 2,123E-03 8,375E-03 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 2,123E-03 8,361E-03 ! neutral lipid catabolic process GO:0046461 13 8 0,000 2,123E-03 8,348E-03 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 2,123E-03 8,334E-03 ! meiotic prophase I GO:0007128 13 8 0,000 2,123E-03 8,32E-03 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 2,123E-03 8,307E-03 ! oligopeptide transport GO:0006857 15 8 0,000 2,123E-03 8,293E-03 ! UTP metabolic process GO:0046051 8 8 0,000 2,123E-03 8,28E-03 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 2,123E-03 8,267E-03 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 2,123E-03 8,253E-03 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 2,123E-03 8,24E-03 ! macrophage chemotaxis GO:0048246 12 8 0,000 2,123E-03 8,227E-03 ! succinate metabolic process GO:0006105 14 8 0,000 2,123E-03 8,213E-03 ! membrane hyperpolarization GO:0060081 10 8 0,000 2,123E-03 8,2E-03 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 2,123E-03 8,187E-03 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 2,123E-03 8,174E-03 ! T-helper 1 type immune response GO:0042088 12 8 0,000 2,123E-03 8,161E-03 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 2,123E-03 8,148E-03 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 2,123E-03 8,135E-03 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 2,123E-03 8,122E-03 ! ganglioside metabolic process GO:0001573 19 8 0,000 2,123E-03 8,109E-03 ! reflex GO:0060004 16 8 0,000 2,123E-03 8,096E-03 ! negative regulation of endocytosis GO:0045806 11 8 0,000 2,123E-03 8,083E-03 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 2,123E-03 8,071E-03 ! endothelial cell differentiation GO:0045446 17 8 0,000 2,123E-03 8,058E-03 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 2,123E-03 8,045E-03 ! glycerolipid catabolic process GO:0046503 13 8 0,000 2,123E-03 8,033E-03 ! hemoglobin metabolic process GO:0020027 13 8 0,000 2,123E-03 8,02E-03 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 2,123E-03 8,007E-03 ! pigment granule organization GO:0048753 16 8 0,000 2,123E-03 7,995E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 2,123E-03 7,982E-03 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 2,123E-03 7,97E-03 ! astrocyte differentiation GO:0048708 18 8 0,000 2,123E-03 7,957E-03 ! histidine metabolic process GO:0006547 16 8 0,000 2,123E-03 7,945E-03 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 2,123E-03 7,933E-03 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 2,123E-03 7,92E-03 ! glycine catabolic process GO:0006546 13 8 0,000 2,123E-03 7,908E-03 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 2,123E-03 7,896E-03 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 2,123E-03 7,884E-03 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 2,123E-03 7,872E-03 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 2,123E-03 7,86E-03 ! regulation of pigmentation during development GO:0048070 24 8 0,000 2,123E-03 7,847E-03 ! melanin metabolic process GO:0006582 15 8 0,000 2,123E-03 7,835E-03 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 2,123E-03 7,823E-03 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 2,123E-03 7,811E-03 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 2,123E-03 7,8E-03 ! macrophage activation GO:0042116 12 8 0,000 2,123E-03 7,788E-03 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 2,123E-03 7,776E-03 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 2,123E-03 7,764E-03 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 2,123E-03 7,752E-03 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 2,123E-03 7,74E-03 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 2,123E-03 7,729E-03 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 2,123E-03 7,717E-03 ! regulation of vascular permeability GO:0043114 12 8 0,000 2,123E-03 7,705E-03 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 2,123E-03 7,694E-03 ! osteoblast development GO:0002076 16 8 0,000 2,123E-03 7,682E-03 ! positive regulation of vasodilation GO:0045909 13 8 0,000 2,123E-03 7,671E-03 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 2,123E-03 7,659E-03 ! negative regulation of translational initiation GO:0045947 10 8 0,000 2,123E-03 7,648E-03 ! Schwann cell differentiation GO:0014037 19 8 0,000 2,123E-03 7,636E-03 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 2,123E-03 7,625E-03 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 2,123E-03 7,614E-03 ! response to UV-B GO:0010224 16 8 0,000 2,123E-03 7,602E-03 ! protein targeting to vacuole GO:0006623 12 8 0,000 2,123E-03 7,591E-03 ! protein retention in ER lumen GO:0006621 14 8 0,000 2,123E-03 7,58E-03 ! intermediate filament organization GO:0045109 12 8 0,000 2,123E-03 7,568E-03 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 2,123E-03 7,557E-03 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 2,123E-03 7,546E-03 ! cellular extravasation GO:0045123 12 8 0,000 2,123E-03 7,535E-03 ! cardiac muscle cell development GO:0055013 13 8 0,000 2,123E-03 7,524E-03 ! regulation of circadian rhythm GO:0042752 16 8 0,000 2,123E-03 7,513E-03 ! response to antibiotic GO:0046677 11 8 0,000 2,123E-03 7,502E-03 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 2,123E-03 7,491E-03 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 2,123E-03 7,48E-03 ! DNA topological change GO:0006265 12 8 0,000 2,123E-03 7,469E-03 ! response to tropane GO:0014073 15 8 0,000 2,123E-03 7,458E-03 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 2,123E-03 7,447E-03 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 2,123E-03 7,436E-03 ! melanosome transport GO:0032402 13 8 0,000 2,123E-03 7,425E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 0,000 2,123E-03 7,415E-03 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 2,123E-03 7,404E-03 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 2,123E-03 7,393E-03 ! mast cell activation GO:0045576 14 8 0,000 2,123E-03 7,383E-03 ! multicellular organismal aging GO:0010259 18 8 0,000 2,123E-03 7,372E-03 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 2,123E-03 7,361E-03 ! dendrite morphogenesis GO:0048813 13 8 0,000 2,123E-03 7,351E-03 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 2,123E-03 7,34E-03 ! nucleosome disassembly GO:0006337 14 8 0,000 2,123E-03 7,33E-03 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 2,123E-03 7,319E-03 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 2,123E-03 7,309E-03 ! leukocyte activation during immune response GO:0002366 13 8 0,000 2,123E-03 7,298E-03 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 2,123E-03 7,288E-03 ! establishment of chromosome localization GO:0051303 12 8 0,000 2,123E-03 7,277E-03 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 2,123E-03 7,267E-03 ! intracellular lipid transport GO:0032365 13 8 0,000 2,123E-03 7,257E-03 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 2,123E-03 7,246E-03 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 2,123E-03 7,236E-03 ! regulation of macrophage activation GO:0043030 15 8 0,000 2,123E-03 7,226E-03 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 2,123E-03 7,216E-03 ! positive regulation of epidermis development GO:0045684 13 8 0,000 2,123E-03 7,206E-03 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 2,123E-03 7,195E-03 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 2,123E-03 7,185E-03 ! hormone catabolic process GO:0042447 17 8 0,000 2,123E-03 7,175E-03 ! positive regulation of glucose import GO:0046326 8 8 0,000 2,123E-03 7,165E-03 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 2,123E-03 7,155E-03 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 2,123E-03 7,145E-03 ! ATP catabolic process GO:0006200 11 8 0,000 2,123E-03 7,135E-03 ! blastocyst growth GO:0001832 19 8 0,000 2,123E-03 7,125E-03 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 2,123E-03 7,115E-03 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 2,123E-03 7,105E-03 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 2,123E-03 7,095E-03 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 2,123E-03 7,086E-03 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 2,123E-03 7,076E-03 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 2,123E-03 7,066E-03 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 2,123E-03 7,056E-03 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 2,123E-03 7,046E-03 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 2,123E-03 7,037E-03 ! amino sugar catabolic process GO:0046348 10 8 0,000 2,123E-03 7,027E-03 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 2,123E-03 7,017E-03 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 2,123E-03 7,008E-03 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 2,123E-03 6,998E-03 ! behavioral response to nicotine GO:0035095 12 8 0,000 2,123E-03 6,989E-03 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 2,123E-03 6,979E-03 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 2,123E-03 6,97E-03 ! NAD biosynthetic process GO:0009435 13 8 0,000 2,123E-03 6,96E-03 ! regulation of developmental growth GO:0048638 15 9 0,000 2,388E-03 7,819E-03 ! axon extension GO:0048675 15 9 0,000 2,388E-03 7,808E-03 ! autophagic vacuole formation GO:0000045 15 9 0,000 2,388E-03 7,797E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 2,388E-03 7,787E-03 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 2,388E-03 7,776E-03 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 2,388E-03 7,766E-03 ! pentose-phosphate shunt GO:0006098 16 9 0,000 2,388E-03 7,755E-03 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 2,388E-03 7,745E-03 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 2,388E-03 7,734E-03 ! cell proliferation in forebrain GO:0021846 15 9 0,000 2,388E-03 7,724E-03 ! phosphate transport GO:0006817 19 9 0,000 2,388E-03 7,714E-03 ! reproductive behavior GO:0019098 19 9 0,000 2,388E-03 7,703E-03 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 2,388E-03 7,693E-03 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 2,388E-03 7,683E-03 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 2,388E-03 7,672E-03 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 2,388E-03 7,662E-03 ! GTP metabolic process GO:0046039 9 9 0,000 2,388E-03 7,652E-03 ! RNA methylation GO:0001510 15 9 0,000 2,388E-03 7,642E-03 ! elastic fiber assembly GO:0048251 15 9 0,000 2,388E-03 7,632E-03 ! induction of positive chemotaxis GO:0050930 15 9 0,000 2,388E-03 7,622E-03 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 2,388E-03 7,611E-03 ! artery development GO:0060840 24 9 0,000 2,388E-03 7,601E-03 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 2,388E-03 7,591E-03 ! regulation of glycolysis GO:0006110 21 9 0,000 2,388E-03 7,581E-03 ! cerebral cortex cell migration GO:0021795 15 9 0,000 2,388E-03 7,571E-03 ! keratinocyte proliferation GO:0043616 14 9 0,000 2,388E-03 7,561E-03 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 2,388E-03 7,551E-03 ! chemosensory behavior GO:0007635 20 9 0,000 2,388E-03 7,541E-03 ! microtubule bundle formation GO:0001578 21 9 0,000 2,388E-03 7,532E-03 ! middle ear morphogenesis GO:0042474 14 9 0,000 2,388E-03 7,522E-03 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 2,388E-03 7,512E-03 ! leukocyte degranulation GO:0043299 16 9 0,000 2,388E-03 7,502E-03 ! bile acid and bile salt transport GO:0015721 13 9 0,000 2,388E-03 7,492E-03 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 2,388E-03 7,483E-03 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 2,388E-03 7,473E-03 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 2,388E-03 7,463E-03 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 2,388E-03 7,453E-03 ! protein targeting to ER GO:0045047 22 9 0,000 2,388E-03 7,444E-03 ! ceramide biosynthetic process GO:0046513 19 9 0,000 2,388E-03 7,434E-03 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 2,388E-03 7,425E-03 ! T cell selection GO:0045058 23 9 0,000 2,388E-03 7,415E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 2,388E-03 7,405E-03 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 2,388E-03 7,396E-03 ! phosphagen metabolic process GO:0006599 12 9 0,000 2,388E-03 7,386E-03 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 2,388E-03 7,377E-03 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 2,388E-03 7,367E-03 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 2,388E-03 7,358E-03 ! regulation of type I interferon production GO:0032479 12 9 0,000 2,388E-03 7,349E-03 ! mannose metabolic process GO:0006013 13 9 0,000 2,388E-03 7,339E-03 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 2,388E-03 7,33E-03 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 2,388E-03 7,321E-03 ! Rac protein signal transduction GO:0016601 17 9 0,000 2,388E-03 7,311E-03 ! receptor clustering GO:0043113 18 9 0,000 2,388E-03 7,302E-03 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 2,388E-03 7,293E-03 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 2,388E-03 7,283E-03 ! ruffle organization GO:0031529 15 9 0,000 2,388E-03 7,274E-03 ! retinol metabolic process GO:0042572 18 9 0,000 2,388E-03 7,265E-03 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 2,388E-03 7,256E-03 ! behavioral fear response GO:0001662 22 9 0,000 2,388E-03 7,247E-03 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 2,388E-03 7,238E-03 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 2,388E-03 7,228E-03 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 2,388E-03 7,219E-03 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 2,388E-03 7,21E-03 ! protein heterooligomerization GO:0051291 16 9 0,000 2,388E-03 7,201E-03 ! oligodendrocyte development GO:0014003 10 9 0,000 2,388E-03 7,192E-03 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 2,388E-03 7,183E-03 ! segment specification GO:0007379 13 9 0,000 2,388E-03 7,174E-03 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 2,388E-03 7,165E-03 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 2,388E-03 7,156E-03 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 2,388E-03 7,148E-03 ! response to amine stimulus GO:0014075 13 9 0,000 2,388E-03 7,139E-03 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 2,388E-03 7,13E-03 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 2,388E-03 7,121E-03 ! erythrocyte development GO:0048821 15 9 0,000 2,388E-03 7,112E-03 ! gas homeostasis GO:0033483 16 9 0,000 2,388E-03 7,103E-03 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 2,388E-03 7,095E-03 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 2,388E-03 7,086E-03 ! renal water homeostasis GO:0003091 14 9 0,000 2,388E-03 7,077E-03 ! postreplication repair GO:0006301 22 9 0,000 2,388E-03 7,068E-03 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 2,388E-03 7,06E-03 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 2,388E-03 7,051E-03 ! icosanoid secretion GO:0032309 15 9 0,000 2,388E-03 7,042E-03 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 2,388E-03 7,034E-03 ! cerebellum morphogenesis GO:0021587 14 9 0,000 2,388E-03 7,025E-03 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 2,388E-03 7,017E-03 ! regulation of cell division GO:0051302 15 9 0,000 2,388E-03 7,008E-03 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 2,388E-03 7E-03 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 2,388E-03 6,991E-03 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 2,388E-03 6,983E-03 ! sterol catabolic process GO:0016127 11 9 0,000 2,388E-03 6,974E-03 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 2,388E-03 6,966E-03 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 2,388E-03 6,957E-03 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 2,388E-03 6,949E-03 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 2,388E-03 6,94E-03 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 2,388E-03 6,932E-03 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 2,388E-03 6,924E-03 ! musculoskeletal movement GO:0050881 14 9 0,000 2,388E-03 6,915E-03 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 2,388E-03 6,907E-03 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 2,388E-03 6,899E-03 ! regulation of synaptogenesis GO:0051963 15 9 0,000 2,388E-03 6,89E-03 ! purine base metabolic process GO:0006144 21 9 0,000 2,388E-03 6,882E-03 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 2,388E-03 6,874E-03 ! pigment granule transport GO:0051904 17 9 0,000 2,388E-03 6,866E-03 ! regulation of fibrinolysis GO:0051917 16 9 0,000 2,388E-03 6,858E-03 ! regulation of telomere maintenance GO:0032204 14 9 0,000 2,388E-03 6,849E-03 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 2,388E-03 6,841E-03 ! regulation of muscle adaptation GO:0043502 14 9 0,000 2,388E-03 6,833E-03 ! regulation of amino acid transport GO:0051955 11 9 0,000 2,388E-03 6,825E-03 ! mitochondrion localization GO:0051646 15 9 0,000 2,388E-03 6,817E-03 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 2,654E-03 7,564E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 2,654E-03 7,555E-03 ! negative regulation of blood pressure GO:0045776 26 10 0,000 2,654E-03 7,547E-03 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 2,654E-03 7,538E-03 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 2,654E-03 7,529E-03 ! regulation of phosphatase activity GO:0010921 28 10 0,000 2,654E-03 7,52E-03 ! synapsis GO:0007129 13 10 0,000 2,654E-03 7,511E-03 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 2,654E-03 7,502E-03 ! N-glycan processing GO:0006491 20 10 0,000 2,654E-03 7,493E-03 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 2,654E-03 7,485E-03 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 2,654E-03 7,476E-03 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 2,654E-03 7,467E-03 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 2,654E-03 7,458E-03 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 2,654E-03 7,45E-03 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 2,654E-03 7,441E-03 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 2,654E-03 7,432E-03 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 2,654E-03 7,424E-03 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 2,654E-03 7,415E-03 ! androgen metabolic process GO:0008209 17 10 0,000 2,654E-03 7,406E-03 ! phospholipid efflux GO:0033700 16 10 0,000 2,654E-03 7,398E-03 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 2,654E-03 7,389E-03 ! positive regulation of heart contraction GO:0045823 16 10 0,000 2,654E-03 7,381E-03 ! lung alveolus development GO:0048286 26 10 0,000 2,654E-03 7,372E-03 ! pathogenesis GO:0009405 13 10 0,000 2,654E-03 7,364E-03 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 2,654E-03 7,355E-03 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 2,654E-03 7,347E-03 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 2,654E-03 7,338E-03 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 2,654E-03 7,33E-03 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 2,654E-03 7,322E-03 ! endoderm development GO:0007492 16 10 0,000 2,654E-03 7,313E-03 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 2,654E-03 7,305E-03 ! arginine catabolic process GO:0006527 13 10 0,000 2,654E-03 7,296E-03 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 2,654E-03 7,288E-03 ! proline metabolic process GO:0006560 13 10 0,000 2,654E-03 7,28E-03 ! glucan biosynthetic process GO:0009250 14 10 0,000 2,654E-03 7,272E-03 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 2,654E-03 7,263E-03 ! polyamine biosynthetic process GO:0006596 12 10 0,000 2,654E-03 7,255E-03 ! V(D)J recombination GO:0033151 28 10 0,000 2,654E-03 7,247E-03 ! reverse cholesterol transport GO:0043691 16 10 0,000 2,654E-03 7,239E-03 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 2,654E-03 7,23E-03 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 2,654E-03 7,222E-03 ! B cell proliferation GO:0042100 18 10 0,000 2,654E-03 7,214E-03 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 2,654E-03 7,206E-03 ! regulation of sodium ion transport GO:0002028 21 10 0,000 2,654E-03 7,198E-03 ! multicellular organism growth GO:0035264 18 10 0,000 2,654E-03 7,19E-03 ! phagocytosis, engulfment GO:0006911 28 10 0,000 2,654E-03 7,182E-03 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 2,654E-03 7,173E-03 ! epithelial cell development GO:0002064 20 10 0,000 2,654E-03 7,165E-03 ! lens development in camera-type eye GO:0002088 16 10 0,000 2,654E-03 7,157E-03 ! retinoic acid metabolic process GO:0042573 14 10 0,000 2,654E-03 7,149E-03 ! macroautophagy GO:0016236 17 10 0,000 2,654E-03 7,141E-03 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 2,654E-03 7,133E-03 ! positive regulation of translational initiation GO:0045948 11 10 0,000 2,654E-03 7,125E-03 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 2,654E-03 7,117E-03 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 2,654E-03 7,11E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 2,654E-03 7,102E-03 ! copper ion homeostasis GO:0055070 13 10 0,000 2,654E-03 7,094E-03 ! regulation of bone resorption GO:0045124 25 10 0,000 2,654E-03 7,086E-03 ! regulation of gliogenesis GO:0014013 23 10 0,000 2,654E-03 7,078E-03 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 2,654E-03 7,07E-03 ! alpha-beta T cell activation GO:0046631 23 10 0,000 2,654E-03 7,062E-03 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 2,654E-03 7,055E-03 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 2,654E-03 7,047E-03 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 2,654E-03 7,039E-03 ! blastoderm segmentation GO:0007350 18 10 0,000 2,654E-03 7,031E-03 ! response to dsRNA GO:0043331 20 10 0,000 2,654E-03 7,024E-03 ! DNA ligation GO:0006266 19 10 0,000 2,654E-03 7,016E-03 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 2,654E-03 7,008E-03 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 2,654E-03 7E-03 ! melanosome localization GO:0032400 16 10 0,000 2,654E-03 6,993E-03 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 2,654E-03 6,985E-03 ! regulation of B cell differentiation GO:0045577 19 10 0,000 2,654E-03 6,977E-03 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 2,654E-03 6,97E-03 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 2,654E-03 6,962E-03 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 2,654E-03 6,955E-03 ! mRNA cleavage GO:0006379 17 10 0,000 2,654E-03 6,947E-03 ! protein sumoylation GO:0016925 15 10 0,000 2,654E-03 6,94E-03 ! hindbrain morphogenesis GO:0021575 19 10 0,000 2,654E-03 6,932E-03 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 2,654E-03 6,925E-03 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 2,654E-03 6,917E-03 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 2,654E-03 6,91E-03 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 2,654E-03 6,902E-03 ! salivary gland development GO:0007431 27 10 0,000 2,654E-03 6,895E-03 ! prophase GO:0051324 15 10 0,000 2,654E-03 6,887E-03 ! negative regulation of neurological system process GO:0031645 19 10 0,000 2,654E-03 6,88E-03 ! apical protein localization GO:0045176 15 10 0,000 2,654E-03 6,872E-03 ! ubiquinone metabolic process GO:0006743 15 10 0,000 2,654E-03 6,865E-03 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 2,654E-03 6,858E-03 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 2,654E-03 6,85E-03 ! midbrain development GO:0030901 13 10 0,000 2,654E-03 6,843E-03 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 2,654E-03 6,836E-03 ! methionine biosynthetic process GO:0009086 19 10 0,000 2,654E-03 6,828E-03 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 2,654E-03 6,821E-03 ! quaternary ammonium group transport GO:0015697 21 10 0,000 2,654E-03 6,814E-03 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 2,654E-03 6,806E-03 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 2,654E-03 6,799E-03 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 2,654E-03 6,792E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 2,654E-03 6,785E-03 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 2,654E-03 6,777E-03 ! oocyte development GO:0048599 17 10 0,000 2,654E-03 6,77E-03 ! establishment of pigment granule localization GO:0051905 18 10 0,000 2,654E-03 6,763E-03 ! blastocyst formation GO:0001825 17 10 0,000 2,654E-03 6,756E-03 ! cerebellar cortex development GO:0021695 15 10 0,000 2,654E-03 6,749E-03 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 2,654E-03 6,742E-03 ! activation of innate immune response GO:0002218 12 10 0,000 2,654E-03 6,735E-03 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 2,654E-03 6,727E-03 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 2,654E-03 6,72E-03 ! response to nicotine GO:0035094 20 10 0,000 2,654E-03 6,713E-03 ! establishment of cell polarity GO:0030010 16 10 0,000 2,654E-03 6,706E-03 ! negative regulation of immune effector process GO:0002698 20 10 0,000 2,654E-03 6,699E-03 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 2,654E-03 6,692E-03 ! localization within membrane GO:0051668 20 10 0,000 2,654E-03 6,685E-03 ! negative regulation of muscle development GO:0048635 20 11 0,000 2,919E-03 7,345E-03 ! respiratory burst GO:0045730 17 11 0,000 2,919E-03 7,338E-03 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 2,919E-03 7,33E-03 ! neuron fate specification GO:0048665 17 11 0,000 2,919E-03 7,322E-03 ! telencephalon cell migration GO:0022029 20 11 0,000 2,919E-03 7,315E-03 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 2,919E-03 7,307E-03 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 2,919E-03 7,299E-03 ! thyroid gland development GO:0030878 26 11 0,000 2,919E-03 7,292E-03 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 2,919E-03 7,284E-03 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 2,919E-03 7,277E-03 ! Golgi vesicle budding GO:0048194 22 11 0,000 2,919E-03 7,269E-03 ! response to pain GO:0048265 24 11 0,000 2,919E-03 7,262E-03 ! detection of mechanical stimulus GO:0050982 22 11 0,000 2,919E-03 7,254E-03 ! T cell proliferation GO:0042098 26 11 0,000 2,919E-03 7,247E-03 ! blood vessel remodeling GO:0001974 29 11 0,000 2,919E-03 7,239E-03 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 2,919E-03 7,232E-03 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 2,919E-03 7,224E-03 ! bone resorption GO:0045453 16 11 0,000 2,919E-03 7,217E-03 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 2,919E-03 7,209E-03 ! ventral spinal cord development GO:0021517 21 11 0,000 2,919E-03 7,202E-03 ! negative regulation of proteolysis GO:0045861 25 11 0,000 2,919E-03 7,195E-03 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 2,919E-03 7,187E-03 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 2,919E-03 7,18E-03 ! melanocyte differentiation GO:0030318 21 11 0,000 2,919E-03 7,173E-03 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 2,919E-03 7,165E-03 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 2,919E-03 7,158E-03 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 2,919E-03 7,151E-03 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 2,919E-03 7,143E-03 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 2,919E-03 7,136E-03 ! lipid digestion GO:0044241 18 11 0,000 2,919E-03 7,129E-03 ! substrate-bound cell migration GO:0006929 13 11 0,000 2,919E-03 7,122E-03 ! UV protection GO:0009650 19 11 0,000 2,919E-03 7,115E-03 ! adult heart development GO:0007512 14 11 0,000 2,919E-03 7,107E-03 ! chondrocyte differentiation GO:0002062 24 11 0,000 2,919E-03 7,1E-03 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 2,919E-03 7,093E-03 ! temperature homeostasis GO:0001659 17 11 0,000 2,919E-03 7,086E-03 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 2,919E-03 7,079E-03 ! negative regulation of ossification GO:0030279 26 11 0,000 2,919E-03 7,072E-03 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 2,919E-03 7,064E-03 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 2,919E-03 7,057E-03 ! regulation of organ growth GO:0046620 13 11 0,000 2,919E-03 7,05E-03 ! pigment granule localization GO:0051875 20 11 0,000 2,919E-03 7,043E-03 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 2,919E-03 7,036E-03 ! vasoconstriction GO:0042310 18 11 0,000 2,919E-03 7,029E-03 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 2,919E-03 7,022E-03 ! embryonic axis specification GO:0000578 18 11 0,000 2,919E-03 7,015E-03 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 2,919E-03 7,008E-03 ! snRNA metabolic process GO:0016073 24 11 0,000 2,919E-03 7,001E-03 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 2,919E-03 6,994E-03 ! nitric oxide metabolic process GO:0046209 15 11 0,000 2,919E-03 6,987E-03 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 2,919E-03 6,98E-03 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 2,919E-03 6,973E-03 ! zymogen activation GO:0031638 15 11 0,000 2,919E-03 6,966E-03 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 2,919E-03 6,959E-03 ! neuroblast proliferation GO:0007405 24 11 0,000 2,919E-03 6,952E-03 ! nucleosome positioning GO:0016584 15 11 0,000 2,919E-03 6,946E-03 ! regulation of isotype switching GO:0045191 22 11 0,000 2,919E-03 6,939E-03 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 2,919E-03 6,932E-03 ! glutathione biosynthetic process GO:0006750 13 11 0,000 2,919E-03 6,925E-03 ! regulation of leukocyte migration GO:0002685 26 11 0,000 2,919E-03 6,918E-03 ! acid secretion GO:0046717 18 11 0,000 2,919E-03 6,911E-03 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 2,919E-03 6,905E-03 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 2,919E-03 6,898E-03 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 2,919E-03 6,891E-03 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 2,919E-03 6,884E-03 ! oocyte differentiation GO:0009994 18 11 0,000 2,919E-03 6,878E-03 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 2,919E-03 6,871E-03 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 2,919E-03 6,864E-03 ! cholesterol efflux GO:0033344 19 11 0,000 2,919E-03 6,857E-03 ! anterior/posterior axis specification GO:0009948 18 11 0,000 2,919E-03 6,851E-03 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 2,919E-03 6,844E-03 ! negative regulation of glucose import GO:0046325 17 11 0,000 2,919E-03 6,837E-03 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 2,919E-03 6,831E-03 ! embryonic gut development GO:0048566 15 11 0,000 2,919E-03 6,824E-03 ! regulation of organic acid transport GO:0032890 18 11 0,000 2,919E-03 6,817E-03 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 2,919E-03 6,811E-03 ! cardiac cell differentiation GO:0035051 31 11 0,000 2,919E-03 6,804E-03 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 2,919E-03 6,798E-03 ! defense response to fungus GO:0050832 13 11 0,000 2,919E-03 6,791E-03 ! developmental induction GO:0031128 19 11 0,000 2,919E-03 6,785E-03 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 2,919E-03 6,778E-03 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 2,919E-03 6,771E-03 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 2,919E-03 6,765E-03 ! sequestering of metal ion GO:0051238 14 11 0,000 2,919E-03 6,758E-03 ! lamellipodium assembly GO:0030032 20 11 0,000 2,919E-03 6,752E-03 ! regulation of embryonic development GO:0045995 27 11 0,000 2,919E-03 6,745E-03 ! nucleus localization GO:0051647 19 11 0,000 2,919E-03 6,739E-03 ! regulation of synapse organization GO:0050807 17 11 0,000 2,919E-03 6,733E-03 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 3,183E-03 7,337E-03 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 3,183E-03 7,33E-03 ! positive regulation of blood pressure GO:0045777 17 12 0,000 3,183E-03 7,323E-03 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 3,183E-03 7,316E-03 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 3,183E-03 7,309E-03 ! virus-host interaction GO:0019048 29 12 0,000 3,183E-03 7,302E-03 ! regulation of B cell proliferation GO:0030888 20 12 0,000 3,183E-03 7,295E-03 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 3,183E-03 7,288E-03 ! cartilage condensation GO:0001502 20 12 0,000 3,183E-03 7,281E-03 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 3,183E-03 7,274E-03 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 3,183E-03 7,267E-03 ! protein complex disassembly GO:0043241 27 12 0,000 3,183E-03 7,26E-03 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 3,183E-03 7,253E-03 ! regulation of cell projection assembly GO:0060491 30 12 0,000 3,183E-03 7,246E-03 ! hippocampus development GO:0021766 26 12 0,000 3,183E-03 7,24E-03 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 3,183E-03 7,233E-03 ! cytokine biosynthetic process GO:0042089 21 12 0,000 3,183E-03 7,226E-03 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 3,183E-03 7,219E-03 ! positive regulation of cell growth GO:0030307 22 12 0,000 3,183E-03 7,212E-03 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 3,183E-03 7,206E-03 ! regulation of exit from mitosis GO:0007096 17 12 0,000 3,183E-03 7,199E-03 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 3,183E-03 7,192E-03 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 3,183E-03 7,185E-03 ! drug transport GO:0015893 16 12 0,000 3,183E-03 7,179E-03 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 3,183E-03 7,172E-03 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 3,183E-03 7,165E-03 ! tyrosine metabolic process GO:0006570 16 12 0,000 3,183E-03 7,158E-03 ! polyamine metabolic process GO:0006595 17 12 0,000 3,183E-03 7,152E-03 ! focal adhesion formation GO:0048041 35 12 0,000 3,183E-03 7,145E-03 ! mitotic spindle organization GO:0007052 21 12 0,000 3,183E-03 7,138E-03 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 3,183E-03 7,132E-03 ! forebrain cell migration GO:0021885 21 12 0,000 3,183E-03 7,125E-03 ! asymmetric protein localization GO:0008105 20 12 0,000 3,183E-03 7,118E-03 ! membrane protein proteolysis GO:0033619 25 12 0,000 3,183E-03 7,112E-03 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 3,183E-03 7,105E-03 ! entry into host cell GO:0030260 32 12 0,000 3,183E-03 7,099E-03 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 3,183E-03 7,092E-03 ! monoamine transport GO:0015844 18 12 0,000 3,183E-03 7,086E-03 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 3,183E-03 7,079E-03 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 3,183E-03 7,072E-03 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 3,183E-03 7,066E-03 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 3,183E-03 7,059E-03 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 3,183E-03 7,053E-03 ! protein targeting to peroxisome GO:0006625 23 12 0,000 3,183E-03 7,046E-03 ! protein homotetramerization GO:0051289 21 12 0,000 3,183E-03 7,04E-03 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 3,183E-03 7,034E-03 ! regulation of phagocytosis GO:0050764 16 12 0,000 3,183E-03 7,027E-03 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 3,183E-03 7,021E-03 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 3,183E-03 7,014E-03 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 3,183E-03 7,008E-03 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 3,183E-03 7,001E-03 ! cranial nerve development GO:0021545 20 12 0,000 3,183E-03 6,995E-03 ! fucose catabolic process GO:0019317 22 12 0,000 3,183E-03 6,989E-03 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 3,183E-03 6,982E-03 ! histone acetylation GO:0016573 26 12 0,000 3,183E-03 6,976E-03 ! histone methylation GO:0016571 26 12 0,000 3,183E-03 6,97E-03 ! mRNA polyadenylation GO:0006378 23 12 0,000 3,183E-03 6,963E-03 ! autonomic nervous system development GO:0048483 24 12 0,000 3,183E-03 6,957E-03 ! gland morphogenesis GO:0022612 29 12 0,000 3,183E-03 6,951E-03 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 3,183E-03 6,944E-03 ! peptidyl-lysine modification GO:0018205 21 12 0,000 3,183E-03 6,938E-03 ! T cell homeostasis GO:0043029 25 12 0,000 3,183E-03 6,932E-03 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 3,183E-03 6,925E-03 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 3,183E-03 6,919E-03 ! spleen development GO:0048536 22 12 0,000 3,183E-03 6,913E-03 ! digestive tract morphogenesis GO:0048546 26 12 0,000 3,183E-03 6,907E-03 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 3,183E-03 6,9E-03 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 3,183E-03 6,894E-03 ! regulation of RNA splicing GO:0043484 20 12 0,000 3,183E-03 6,888E-03 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 3,183E-03 6,882E-03 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 3,183E-03 6,876E-03 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 3,183E-03 6,869E-03 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 3,183E-03 6,863E-03 ! response to cold GO:0009409 17 12 0,000 3,183E-03 6,857E-03 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 3,183E-03 6,851E-03 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 3,183E-03 6,845E-03 ! cGMP metabolic process GO:0046068 18 13 0,000 3,448E-03 7,408E-03 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 3,448E-03 7,401E-03 ! regulation of chemokine production GO:0032642 18 13 0,000 3,448E-03 7,395E-03 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 3,448E-03 7,388E-03 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 3,448E-03 7,382E-03 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 3,448E-03 7,375E-03 ! lipid localization GO:0010876 28 13 0,000 3,448E-03 7,368E-03 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 3,448E-03 7,362E-03 ! organelle fusion GO:0048284 32 13 0,000 3,448E-03 7,355E-03 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 3,448E-03 7,349E-03 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 3,448E-03 7,342E-03 ! pseudouridine synthesis GO:0001522 17 13 0,000 3,448E-03 7,336E-03 ! endocrine pancreas development GO:0031018 22 13 0,000 3,448E-03 7,329E-03 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 3,448E-03 7,323E-03 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 3,448E-03 7,316E-03 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 3,448E-03 7,31E-03 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 3,448E-03 7,304E-03 ! methionine metabolic process GO:0006555 27 13 0,000 3,448E-03 7,297E-03 ! plasma membrane organization GO:0007009 24 13 0,000 3,448E-03 7,291E-03 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 3,448E-03 7,284E-03 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 3,448E-03 7,278E-03 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 3,448E-03 7,272E-03 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 3,448E-03 7,265E-03 ! cell-cell junction assembly GO:0007043 27 13 0,000 3,448E-03 7,259E-03 ! response to X-ray GO:0010165 25 13 0,000 3,448E-03 7,252E-03 ! cytokine metabolic process GO:0042107 22 13 0,000 3,448E-03 7,246E-03 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 3,448E-03 7,24E-03 ! exocrine system development GO:0035272 32 13 0,000 3,448E-03 7,233E-03 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 3,448E-03 7,227E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 3,448E-03 7,221E-03 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 3,448E-03 7,215E-03 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 3,448E-03 7,208E-03 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 3,448E-03 7,202E-03 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 3,448E-03 7,196E-03 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 3,448E-03 7,19E-03 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 3,448E-03 7,183E-03 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 3,448E-03 7,177E-03 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 3,448E-03 7,171E-03 ! regulation of cellular pH GO:0030641 22 13 0,000 3,448E-03 7,165E-03 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 3,448E-03 7,159E-03 ! ribosome assembly GO:0042255 17 13 0,000 3,448E-03 7,152E-03 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 3,448E-03 7,146E-03 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 3,448E-03 7,14E-03 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 3,448E-03 7,134E-03 ! chromatin silencing GO:0006342 26 13 0,000 3,448E-03 7,128E-03 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 3,448E-03 7,122E-03 ! regulation of epidermis development GO:0045682 19 13 0,000 3,448E-03 7,116E-03 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 3,448E-03 7,11E-03 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 3,448E-03 7,103E-03 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 3,448E-03 7,097E-03 ! regulation of mRNA stability GO:0043488 31 13 0,000 3,448E-03 7,091E-03 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 3,448E-03 7,085E-03 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 3,448E-03 7,079E-03 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 3,448E-03 7,073E-03 ! mRNA 3'-end processing GO:0031124 24 13 0,000 3,448E-03 7,067E-03 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 3,448E-03 7,061E-03 ! embryonic placenta development GO:0001892 23 13 0,000 3,448E-03 7,055E-03 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 3,448E-03 7,049E-03 ! insulin secretion GO:0030073 23 13 0,000 3,448E-03 7,043E-03 ! actin filament polymerization GO:0030041 24 13 0,000 3,448E-03 7,037E-03 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 3,448E-03 7,031E-03 ! acrosome reaction GO:0007340 18 13 0,000 3,448E-03 7,025E-03 ! rRNA transcription GO:0009303 25 14 0,000 3,713E-03 7,558E-03 ! lactation GO:0007595 26 14 0,000 3,713E-03 7,552E-03 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 3,713E-03 7,546E-03 ! reproductive cellular process GO:0048610 20 14 0,000 3,713E-03 7,539E-03 ! tRNA modification GO:0006400 20 14 0,000 3,713E-03 7,533E-03 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 3,713E-03 7,527E-03 ! regulation of S phase GO:0033261 23 14 0,000 3,713E-03 7,52E-03 ! water transport GO:0006833 21 14 0,000 3,713E-03 7,514E-03 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 3,713E-03 7,508E-03 ! non-recombinational repair GO:0000726 25 14 0,000 3,713E-03 7,501E-03 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 3,713E-03 7,495E-03 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 3,713E-03 7,489E-03 ! retina development in camera-type eye GO:0060041 27 14 0,000 3,713E-03 7,482E-03 ! hair follicle morphogenesis GO:0031069 26 14 0,000 3,713E-03 7,476E-03 ! RNA polyadenylation GO:0043631 30 14 0,000 3,713E-03 7,47E-03 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 3,713E-03 7,464E-03 ! palate development GO:0060021 31 14 0,000 3,713E-03 7,457E-03 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 3,713E-03 7,451E-03 ! regulated secretory pathway GO:0045055 23 14 0,000 3,713E-03 7,445E-03 ! regulation of mRNA processing GO:0050684 24 14 0,000 3,713E-03 7,439E-03 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 3,713E-03 7,433E-03 ! arginine metabolic process GO:0006525 17 14 0,000 3,713E-03 7,426E-03 ! regulation of heart rate GO:0002027 24 14 0,000 3,713E-03 7,42E-03 ! organic alcohol transport GO:0015850 29 14 0,000 3,713E-03 7,414E-03 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 3,713E-03 7,408E-03 ! negative regulation of caspase activity GO:0043154 22 14 0,000 3,713E-03 7,402E-03 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 3,713E-03 7,396E-03 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 3,713E-03 7,39E-03 ! neutral amino acid transport GO:0015804 26 14 0,000 3,713E-03 7,383E-03 ! L-amino acid transport GO:0015807 30 14 0,000 3,713E-03 7,377E-03 ! bone mineralization GO:0030282 17 14 0,000 3,713E-03 7,371E-03 ! stem cell development GO:0048864 43 14 0,000 3,713E-03 7,365E-03 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 3,713E-03 7,359E-03 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 3,713E-03 7,353E-03 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 3,713E-03 7,347E-03 ! cerebellum development GO:0021549 21 14 0,000 3,713E-03 7,341E-03 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 3,713E-03 7,335E-03 ! negative regulation of protein secretion GO:0050709 28 14 0,000 3,713E-03 7,329E-03 ! response to gamma radiation GO:0010332 28 14 0,000 3,713E-03 7,323E-03 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 3,713E-03 7,317E-03 ! cofactor transport GO:0051181 26 14 0,000 3,713E-03 7,311E-03 ! NADP metabolic process GO:0006739 24 14 0,000 3,713E-03 7,305E-03 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 3,713E-03 7,299E-03 ! protein-chromophore linkage GO:0018298 19 14 0,000 3,713E-03 7,293E-03 ! intestinal absorption GO:0050892 25 14 0,000 3,713E-03 7,287E-03 ! cAMP biosynthetic process GO:0006171 23 14 0,000 3,713E-03 7,281E-03 ! oxygen transport GO:0015671 21 14 0,000 3,713E-03 7,275E-03 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 3,713E-03 7,269E-03 ! male genitalia development GO:0030539 24 14 0,000 3,713E-03 7,263E-03 ! regulation of RNA stability GO:0043487 32 14 0,000 3,713E-03 7,258E-03 ! regulation of axon extension GO:0030516 37 14 0,000 3,713E-03 7,252E-03 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 3,713E-03 7,246E-03 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 3,713E-03 7,24E-03 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 3,978E-03 7,75E-03 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 3,978E-03 7,744E-03 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 3,978E-03 7,737E-03 ! superoxide anion generation GO:0042554 20 15 0,000 3,978E-03 7,731E-03 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 3,978E-03 7,725E-03 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 3,978E-03 7,719E-03 ! phospholipid catabolic process GO:0009395 22 15 0,000 3,978E-03 7,712E-03 ! copper ion transport GO:0006825 20 15 0,000 3,978E-03 7,706E-03 ! heterophilic cell adhesion GO:0007157 39 15 0,000 3,978E-03 7,7E-03 ! cardiac muscle contraction GO:0060048 26 15 0,000 3,978E-03 7,694E-03 ! sulfate transport GO:0008272 23 15 0,000 3,978E-03 7,688E-03 ! response to cAMP GO:0051591 22 15 0,000 3,978E-03 7,681E-03 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 3,978E-03 7,675E-03 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 3,978E-03 7,669E-03 ! ciliary or flagellar motility GO:0001539 20 15 0,000 3,978E-03 7,663E-03 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 3,978E-03 7,657E-03 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 3,978E-03 7,651E-03 ! response to hexose stimulus GO:0009746 22 15 0,000 3,978E-03 7,645E-03 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 3,978E-03 7,638E-03 ! glycoprotein catabolic process GO:0006516 26 15 0,000 3,978E-03 7,632E-03 ! pituitary gland development GO:0021983 29 15 0,000 3,978E-03 7,626E-03 ! vesicle coating GO:0006901 33 15 0,000 3,978E-03 7,62E-03 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 3,978E-03 7,614E-03 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 3,978E-03 7,608E-03 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 3,978E-03 7,602E-03 ! regulation of exocytosis GO:0017157 22 15 0,000 3,978E-03 7,596E-03 ! G1/S transition checkpoint GO:0031575 40 15 0,000 3,978E-03 7,59E-03 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 3,978E-03 7,584E-03 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 3,978E-03 7,578E-03 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 3,978E-03 7,572E-03 ! regulation of vasodilation GO:0042312 26 15 0,000 3,978E-03 7,566E-03 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 3,978E-03 7,56E-03 ! histone deacetylation GO:0016575 20 15 0,000 3,978E-03 7,554E-03 ! mRNA splice site selection GO:0006376 38 15 0,000 3,978E-03 7,548E-03 ! tissue regeneration GO:0042246 26 15 0,000 3,978E-03 7,542E-03 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 3,978E-03 7,536E-03 ! water homeostasis GO:0030104 27 15 0,000 3,978E-03 7,53E-03 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 3,978E-03 7,524E-03 ! muscle maintenance GO:0046716 26 15 0,000 3,978E-03 7,518E-03 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 3,978E-03 7,513E-03 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 3,978E-03 7,507E-03 ! regulation of ATPase activity GO:0043462 21 15 0,000 3,978E-03 7,501E-03 ! dopamine metabolic process GO:0042417 35 15 0,000 3,978E-03 7,495E-03 ! heme biosynthetic process GO:0006783 29 15 0,000 3,978E-03 7,489E-03 ! cell killing GO:0001906 29 15 0,000 3,978E-03 7,483E-03 ! lymphocyte homeostasis GO:0002260 30 15 0,000 3,978E-03 7,477E-03 ! detection of bacterium GO:0016045 18 15 0,000 3,978E-03 7,472E-03 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 3,978E-03 7,466E-03 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 3,978E-03 7,46E-03 ! L-fucose metabolic process GO:0042354 30 15 0,000 3,978E-03 7,454E-03 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 3,978E-03 7,448E-03 ! peptide hormone processing GO:0016486 23 15 0,000 3,978E-03 7,442E-03 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 4,243E-03 7,932E-03 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 4,243E-03 7,925E-03 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 4,243E-03 7,919E-03 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 4,243E-03 7,913E-03 ! dicarboxylic acid transport GO:0006835 38 16 0,000 4,243E-03 7,907E-03 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 4,243E-03 7,901E-03 ! bone remodeling GO:0046849 27 16 0,000 4,243E-03 7,895E-03 ! filopodium assembly GO:0046847 32 16 0,000 4,243E-03 7,889E-03 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 4,243E-03 7,883E-03 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 4,243E-03 7,876E-03 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 4,243E-03 7,87E-03 ! positive regulation of ion transport GO:0043270 21 16 0,000 4,243E-03 7,864E-03 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 4,243E-03 7,858E-03 ! startle response GO:0001964 28 16 0,000 4,243E-03 7,852E-03 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 4,243E-03 7,846E-03 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 4,243E-03 7,84E-03 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 4,243E-03 7,834E-03 ! activation of MAPKK activity GO:0000186 35 16 0,000 4,243E-03 7,828E-03 ! regulation of defense response to virus GO:0050688 27 16 0,000 4,243E-03 7,822E-03 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 4,243E-03 7,816E-03 ! protein polyubiquitination GO:0000209 34 16 0,000 4,243E-03 7,81E-03 ! glutamate metabolic process GO:0006536 22 16 0,000 4,243E-03 7,804E-03 ! complement activation, alternative pathway GO:0006957 18 16 0,000 4,243E-03 7,798E-03 ! response to osmotic stress GO:0006970 25 16 0,000 4,243E-03 7,792E-03 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 4,243E-03 7,786E-03 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 4,243E-03 7,78E-03 ! fructose metabolic process GO:0006000 25 16 0,000 4,243E-03 7,774E-03 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 4,243E-03 7,769E-03 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 4,243E-03 7,763E-03 ! intermediate filament-based process GO:0045103 32 16 0,000 4,243E-03 7,757E-03 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 4,243E-03 7,751E-03 ! negative regulation of immune response GO:0050777 35 16 0,000 4,243E-03 7,745E-03 ! axon cargo transport GO:0008088 43 16 0,000 4,243E-03 7,739E-03 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 4,243E-03 7,733E-03 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 4,243E-03 7,727E-03 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 4,243E-03 7,722E-03 ! DNA replication initiation GO:0006270 27 16 0,000 4,243E-03 7,716E-03 ! neuron recognition GO:0008038 35 16 0,000 4,243E-03 7,71E-03 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 4,243E-03 7,704E-03 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 4,243E-03 7,698E-03 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 4,243E-03 7,692E-03 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 4,243E-03 7,687E-03 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 4,243E-03 7,681E-03 ! sphingolipid catabolic process GO:0030149 27 16 0,000 4,243E-03 7,675E-03 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 4,243E-03 7,669E-03 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 4,243E-03 7,664E-03 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 4,243E-03 7,658E-03 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 4,243E-03 7,652E-03 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 4,243E-03 7,646E-03 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 4,243E-03 7,641E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 4,243E-03 7,635E-03 ! defense response to virus GO:0051607 37 16 0,000 4,243E-03 7,629E-03 ! positive regulation of cell killing GO:0031343 32 17 0,000 4,507E-03 8,099E-03 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 4,507E-03 8,093E-03 ! metencephalon development GO:0022037 30 17 0,000 4,507E-03 8,087E-03 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 4,507E-03 8,081E-03 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 4,507E-03 8,075E-03 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 4,507E-03 8,069E-03 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 4,507E-03 8,063E-03 ! signal complex assembly GO:0007172 41 17 0,000 4,507E-03 8,057E-03 ! endothelial cell migration GO:0043542 28 17 0,000 4,507E-03 8,051E-03 ! inositol metabolic process GO:0006020 28 17 0,000 4,507E-03 8,045E-03 ! gene silencing by RNA GO:0031047 36 17 0,000 4,507E-03 8,039E-03 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 4,507E-03 8,033E-03 ! glial cell development GO:0021782 27 17 0,000 4,507E-03 8,027E-03 ! limbic system development GO:0021761 36 17 0,000 4,507E-03 8,021E-03 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 4,507E-03 8,015E-03 ! adult walking behavior GO:0007628 33 17 0,000 4,507E-03 8,009E-03 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 4,507E-03 8,003E-03 ! heart looping GO:0001947 30 17 0,000 4,507E-03 7,998E-03 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 4,507E-03 7,992E-03 ! regulation of viral genome replication GO:0045069 28 17 0,000 4,507E-03 7,986E-03 ! myoblast differentiation GO:0045445 45 17 0,000 4,507E-03 7,98E-03 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 4,507E-03 7,974E-03 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 4,507E-03 7,968E-03 ! regulation of survival gene product expression GO:0045884 33 17 0,000 4,507E-03 7,962E-03 ! cardiac muscle tissue development GO:0048738 31 17 0,000 4,507E-03 7,956E-03 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 4,507E-03 7,951E-03 ! glycine metabolic process GO:0006544 28 17 0,000 4,507E-03 7,945E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 4,507E-03 7,939E-03 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 4,507E-03 7,933E-03 ! NAD metabolic process GO:0019674 29 17 0,000 4,507E-03 7,927E-03 ! membrane budding GO:0006900 37 17 0,000 4,507E-03 7,922E-03 ! DNA integration GO:0015074 29 17 0,000 4,507E-03 7,916E-03 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 4,507E-03 7,91E-03 ! regulation of protein binding GO:0043393 33 17 0,000 4,507E-03 7,904E-03 ! nucleobase metabolic process GO:0009112 37 17 0,000 4,507E-03 7,899E-03 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 4,507E-03 7,893E-03 ! DNA unwinding during replication GO:0006268 27 17 0,000 4,507E-03 7,887E-03 ! genitalia development GO:0048806 30 17 0,000 4,507E-03 7,881E-03 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 4,507E-03 7,876E-03 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 4,507E-03 7,87E-03 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 4,507E-03 7,864E-03 ! neutrophil chemotaxis GO:0030593 27 17 0,000 4,507E-03 7,858E-03 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 4,507E-03 7,853E-03 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 4,507E-03 7,847E-03 ! steroid catabolic process GO:0006706 31 17 0,000 4,507E-03 7,841E-03 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 4,507E-03 7,836E-03 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 4,507E-03 7,83E-03 ! gas transport GO:0015669 25 17 0,000 4,507E-03 7,824E-03 ! organic cation transport GO:0015695 31 17 0,000 4,507E-03 7,819E-03 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 4,507E-03 7,813E-03 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 4,507E-03 7,808E-03 ! RNA 3'-end processing GO:0031123 34 17 0,000 4,507E-03 7,802E-03 ! microspike assembly GO:0030035 36 17 0,000 4,507E-03 7,796E-03 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 4,507E-03 7,791E-03 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 4,507E-03 7,785E-03 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 4,772E-03 8,236E-03 ! neuron maturation GO:0042551 42 18 0,000 4,772E-03 8,23E-03 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 4,772E-03 8,224E-03 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 4,772E-03 8,218E-03 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 4,772E-03 8,213E-03 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 4,772E-03 8,207E-03 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 4,772E-03 8,201E-03 ! aminoglycan catabolic process GO:0006026 22 18 0,000 4,772E-03 8,195E-03 ! memory GO:0007613 31 18 0,000 4,772E-03 8,189E-03 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 4,772E-03 8,183E-03 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 4,772E-03 8,178E-03 ! patterning of blood vessels GO:0001569 39 18 0,000 4,772E-03 8,172E-03 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 4,772E-03 8,166E-03 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 4,772E-03 8,16E-03 ! positive regulation of proteolysis GO:0045862 31 18 0,000 4,772E-03 8,154E-03 ! epidermis morphogenesis GO:0048730 40 18 0,000 4,772E-03 8,148E-03 ! glutamine metabolic process GO:0006541 29 18 0,000 4,772E-03 8,143E-03 ! response to retinoic acid GO:0032526 26 18 0,000 4,772E-03 8,137E-03 ! cell-substrate junction assembly GO:0007044 54 18 0,000 4,772E-03 8,131E-03 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 4,772E-03 8,125E-03 ! response to fungus GO:0009620 21 18 0,000 4,772E-03 8,12E-03 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 4,772E-03 8,114E-03 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 4,772E-03 8,108E-03 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 4,772E-03 8,102E-03 ! long-chain fatty acid transport GO:0015909 31 18 0,000 4,772E-03 8,097E-03 ! peptide biosynthetic process GO:0043043 24 18 0,000 4,772E-03 8,091E-03 ! vitamin transport GO:0051180 27 18 0,000 4,772E-03 8,085E-03 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 4,772E-03 8,08E-03 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 4,772E-03 8,074E-03 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 4,772E-03 8,068E-03 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 4,772E-03 8,063E-03 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 4,772E-03 8,057E-03 ! aromatic compound catabolic process GO:0019439 27 18 0,000 4,772E-03 8,051E-03 ! nerve development GO:0021675 28 18 0,000 4,772E-03 8,046E-03 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 4,772E-03 8,04E-03 ! protein secretion GO:0009306 39 19 0,000 5,036E-03 8,48E-03 ! positive regulation of translation GO:0045727 30 19 0,000 5,036E-03 8,474E-03 ! negative regulation of defense response GO:0031348 25 19 0,000 5,036E-03 8,468E-03 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 5,036E-03 8,462E-03 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 5,036E-03 8,456E-03 ! skin development GO:0043588 36 19 0,000 5,036E-03 8,45E-03 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 5,036E-03 8,444E-03 ! lipid phosphorylation GO:0046834 35 19 0,000 5,036E-03 8,438E-03 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 5,036E-03 8,433E-03 ! forelimb morphogenesis GO:0035136 32 19 0,000 5,036E-03 8,427E-03 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 5,036E-03 8,421E-03 ! bile acid metabolic process GO:0008206 29 19 0,000 5,036E-03 8,415E-03 ! mitotic chromosome condensation GO:0007076 34 19 0,000 5,036E-03 8,409E-03 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 5,036E-03 8,403E-03 ! cerebral cortex development GO:0021987 36 19 0,000 5,036E-03 8,398E-03 ! pigmentation during development GO:0048066 41 19 0,000 5,036E-03 8,392E-03 ! response to vitamin A GO:0033189 27 19 0,000 5,036E-03 8,386E-03 ! heme metabolic process GO:0042168 36 19 0,000 5,036E-03 8,38E-03 ! actin filament bundle formation GO:0051017 42 19 0,000 5,036E-03 8,374E-03 ! neuromuscular junction development GO:0007528 34 19 0,000 5,036E-03 8,369E-03 ! response to lipopolysaccharide GO:0032496 30 19 0,000 5,036E-03 8,363E-03 ! plasma membrane fusion GO:0045026 28 19 0,000 5,036E-03 8,357E-03 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 5,036E-03 8,351E-03 ! peptide cross-linking GO:0018149 37 19 0,000 5,036E-03 8,346E-03 ! protein export from nucleus GO:0006611 36 19 0,000 5,036E-03 8,34E-03 ! heart process GO:0003015 30 19 0,000 5,036E-03 8,334E-03 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 5,036E-03 8,328E-03 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 5,036E-03 8,323E-03 ! visual learning GO:0008542 36 19 0,000 5,036E-03 8,317E-03 ! cellular pigmentation GO:0033059 36 19 0,000 5,036E-03 8,311E-03 ! G1 phase GO:0051318 40 19 0,000 5,036E-03 8,305E-03 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 5,036E-03 8,3E-03 ! cell-cell junction organization GO:0045216 35 19 0,000 5,036E-03 8,294E-03 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 5,036E-03 8,288E-03 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 5,036E-03 8,283E-03 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 5,036E-03 8,277E-03 ! proximal/distal pattern formation GO:0009954 32 19 0,000 5,036E-03 8,271E-03 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 5,036E-03 8,266E-03 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 5,036E-03 8,26E-03 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 5,036E-03 8,255E-03 ! cilium assembly GO:0042384 37 19 0,000 5,036E-03 8,249E-03 ! peptide hormone secretion GO:0030072 31 19 0,000 5,036E-03 8,243E-03 ! protein import into nucleus, docking GO:0000059 41 20 0,000 5,301E-03 8,67E-03 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 5,301E-03 8,664E-03 ! positive regulation of ossification GO:0045778 47 20 0,000 5,301E-03 8,658E-03 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 5,301E-03 8,653E-03 ! protein amino acid deacetylation GO:0006476 29 20 0,000 5,301E-03 8,647E-03 ! protein amino acid acetylation GO:0006473 39 20 0,000 5,301E-03 8,641E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 5,301E-03 8,635E-03 ! cAMP metabolic process GO:0046058 36 20 0,000 5,301E-03 8,629E-03 ! response to vitamin GO:0033273 31 20 0,000 5,301E-03 8,623E-03 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 5,301E-03 8,618E-03 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 5,301E-03 8,612E-03 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 5,301E-03 8,606E-03 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 5,301E-03 8,6E-03 ! response to alkaloid GO:0043279 38 20 0,000 5,301E-03 8,594E-03 ! retinoid metabolic process GO:0001523 32 20 0,000 5,301E-03 8,589E-03 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 5,301E-03 8,583E-03 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 5,301E-03 8,577E-03 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 5,301E-03 8,571E-03 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 5,301E-03 8,565E-03 ! DNA duplex unwinding GO:0032508 31 20 0,000 5,301E-03 8,56E-03 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 5,301E-03 8,554E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 5,301E-03 8,548E-03 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 5,301E-03 8,543E-03 ! D-ribose metabolic process GO:0006014 29 20 0,000 5,301E-03 8,537E-03 ! body fluid secretion GO:0007589 31 20 0,000 5,301E-03 8,531E-03 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 5,301E-03 8,525E-03 ! peptide secretion GO:0002790 35 20 0,000 5,301E-03 8,52E-03 ! stem cell differentiation GO:0048863 53 20 0,000 5,301E-03 8,514E-03 ! behavioral interaction between organisms GO:0051705 38 20 0,000 5,301E-03 8,508E-03 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 5,301E-03 8,503E-03 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 5,301E-03 8,497E-03 ! sensory perception of pain GO:0019233 30 20 0,000 5,301E-03 8,491E-03 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 5,301E-03 8,486E-03 ! diencephalon development GO:0021536 34 20 0,000 5,301E-03 8,48E-03 ! protein localization in mitochondrion GO:0070585 32 20 0,000 5,301E-03 8,474E-03 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 5,301E-03 8,469E-03 ! detection of chemical stimulus GO:0009593 37 20 0,000 5,301E-03 8,463E-03 ! peptidyl-serine modification GO:0018209 43 20 0,000 5,301E-03 8,458E-03 ! positive regulation of neurological system process GO:0031646 32 20 0,000 5,301E-03 8,452E-03 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 5,301E-03 8,446E-03 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 5,301E-03 8,441E-03 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 5,301E-03 8,435E-03 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 5,301E-03 8,43E-03 ! regulation of glucose import GO:0046324 29 20 0,000 5,301E-03 8,424E-03 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 5,301E-03 8,418E-03 ! actin filament-based movement GO:0030048 43 20 0,000 5,301E-03 8,413E-03 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 5,301E-03 8,407E-03 ! negative regulation of T cell activation GO:0050868 40 20 0,000 5,301E-03 8,402E-03 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 5,301E-03 8,396E-03 ! negative regulation of translation GO:0017148 29 20 0,000 5,301E-03 8,391E-03 ! negative regulation of coagulation GO:0050819 29 20 0,000 5,301E-03 8,385E-03 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 5,301E-03 8,38E-03 ! regulation of cell killing GO:0031341 42 21 0,000 5,565E-03 8,792E-03 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 5,565E-03 8,786E-03 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 5,565E-03 8,78E-03 ! hormone secretion GO:0046879 38 21 0,000 5,565E-03 8,775E-03 ! glycerol metabolic process GO:0006071 34 21 0,000 5,565E-03 8,769E-03 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 5,565E-03 8,763E-03 ! hindlimb morphogenesis GO:0035137 43 21 0,000 5,565E-03 8,757E-03 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 5,565E-03 8,752E-03 ! axis specification GO:0009798 38 21 0,000 5,565E-03 8,746E-03 ! ovarian follicle development GO:0001541 35 21 0,000 5,565E-03 8,74E-03 ! inactivation of MAPK activity GO:0000188 39 21 0,000 5,565E-03 8,735E-03 ! smooth muscle contraction GO:0006939 46 21 0,000 5,565E-03 8,729E-03 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 5,565E-03 8,723E-03 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 5,565E-03 8,718E-03 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 5,565E-03 8,712E-03 ! cell aging GO:0007569 44 21 0,000 5,565E-03 8,706E-03 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 5,565E-03 8,701E-03 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 5,565E-03 8,695E-03 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 5,565E-03 8,689E-03 ! cytolysis GO:0019835 24 21 0,000 5,565E-03 8,684E-03 ! vasodilation GO:0042311 39 21 0,000 5,565E-03 8,678E-03 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 5,565E-03 8,672E-03 ! regulation of vasoconstriction GO:0019229 39 21 0,000 5,565E-03 8,667E-03 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 5,565E-03 8,661E-03 ! oogenesis GO:0048477 36 21 0,000 5,565E-03 8,656E-03 ! DNA modification GO:0006304 34 21 0,000 5,565E-03 8,65E-03 ! positive regulation of locomotion GO:0040017 39 21 0,000 5,565E-03 8,644E-03 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 5,565E-03 8,639E-03 ! detection of biotic stimulus GO:0009595 29 21 0,000 5,565E-03 8,633E-03 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 5,565E-03 8,628E-03 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 5,565E-03 8,622E-03 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 5,565E-03 8,617E-03 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 5,565E-03 8,611E-03 ! vitamin A metabolic process GO:0006776 33 21 0,000 5,565E-03 8,605E-03 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 5,565E-03 8,6E-03 ! response to cytokine stimulus GO:0034097 63 21 0,000 5,565E-03 8,594E-03 ! terpenoid metabolic process GO:0006721 37 21 0,000 5,565E-03 8,589E-03 ! collagen catabolic process GO:0030574 28 21 0,000 5,565E-03 8,583E-03 ! sperm-egg recognition GO:0035036 21 21 0,000 5,565E-03 8,578E-03 ! gut development GO:0048565 39 21 0,000 5,565E-03 8,572E-03 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 5,83E-03 8,974E-03 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 5,83E-03 8,968E-03 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 5,83E-03 8,962E-03 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 5,83E-03 8,957E-03 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 5,83E-03 8,951E-03 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 5,83E-03 8,945E-03 ! regulation of chemotaxis GO:0050920 40 22 0,000 5,83E-03 8,94E-03 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 5,83E-03 8,934E-03 ! glutamate signaling pathway GO:0007215 41 22 0,000 5,83E-03 8,928E-03 ! regeneration GO:0031099 41 22 0,000 5,83E-03 8,922E-03 ! keratinization GO:0031424 28 22 0,000 5,83E-03 8,917E-03 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 5,83E-03 8,911E-03 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 5,83E-03 8,905E-03 ! sensory perception of taste GO:0050909 28 22 0,000 5,83E-03 8,9E-03 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 5,83E-03 8,894E-03 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 5,83E-03 8,889E-03 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 5,83E-03 8,883E-03 ! vacuolar transport GO:0007034 36 22 0,000 5,83E-03 8,877E-03 ! lysosome organization GO:0007040 41 22 0,000 5,83E-03 8,872E-03 ! central nervous system neuron development GO:0021954 46 22 0,000 5,83E-03 8,866E-03 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 5,83E-03 8,86E-03 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 5,83E-03 8,855E-03 ! fucose metabolic process GO:0006004 39 22 0,000 5,83E-03 8,849E-03 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 5,83E-03 8,844E-03 ! apoptotic nuclear changes GO:0030262 32 22 0,000 5,83E-03 8,838E-03 ! ureteric bud development GO:0001657 43 22 0,000 5,83E-03 8,833E-03 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 5,83E-03 8,827E-03 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 5,83E-03 8,821E-03 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 5,83E-03 8,816E-03 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 5,83E-03 8,81E-03 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 5,83E-03 8,805E-03 ! regulation of cytokine secretion GO:0050707 37 22 0,000 5,83E-03 8,799E-03 ! sarcomere organization GO:0045214 30 22 0,000 5,83E-03 8,794E-03 ! positive regulation of B cell activation GO:0050871 38 22 0,000 5,83E-03 8,788E-03 ! activation of JUN kinase activity GO:0007257 42 22 0,000 5,83E-03 8,783E-03 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 5,83E-03 8,777E-03 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 5,83E-03 8,772E-03 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 5,83E-03 8,766E-03 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 5,83E-03 8,761E-03 ! protein stabilization GO:0050821 39 22 0,000 5,83E-03 8,755E-03 ! positive regulation of DNA replication GO:0045740 43 23 0,000 6,094E-03 9,147E-03 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 6,094E-03 9,141E-03 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 6,094E-03 9,135E-03 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 6,094E-03 9,129E-03 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 6,094E-03 9,124E-03 ! gluconeogenesis GO:0006094 33 23 0,000 6,094E-03 9,118E-03 ! viral genome replication GO:0019079 41 23 0,000 6,094E-03 9,112E-03 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 6,094E-03 9,107E-03 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 6,094E-03 9,101E-03 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 6,094E-03 9,095E-03 ! glucosamine metabolic process GO:0006041 30 23 0,000 6,094E-03 9,09E-03 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 6,094E-03 9,084E-03 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 6,094E-03 9,079E-03 ! visual behavior GO:0007632 42 23 0,000 6,094E-03 9,073E-03 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 6,094E-03 9,067E-03 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 6,094E-03 9,062E-03 ! response to ethanol GO:0045471 46 23 0,000 6,094E-03 9,056E-03 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 6,094E-03 9,051E-03 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 6,094E-03 9,045E-03 ! peroxisome organization GO:0007031 37 23 0,000 6,094E-03 9,039E-03 ! polysaccharide catabolic process GO:0000272 27 23 0,000 6,094E-03 9,034E-03 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 6,094E-03 9,028E-03 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 6,094E-03 9,023E-03 ! barbed-end actin filament capping GO:0051016 50 23 0,000 6,094E-03 9,017E-03 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 6,094E-03 9,012E-03 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 6,094E-03 9,006E-03 ! regulation of viral reproduction GO:0050792 38 23 0,000 6,094E-03 9,001E-03 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 6,094E-03 8,995E-03 ! leukotriene metabolic process GO:0006691 42 23 0,000 6,094E-03 8,99E-03 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 6,094E-03 8,984E-03 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 6,094E-03 8,979E-03 ! synaptic vesicle transport GO:0048489 46 23 0,000 6,094E-03 8,973E-03 ! fatty acid transport GO:0015908 44 23 0,000 6,094E-03 8,968E-03 ! platelet activation GO:0030168 37 23 0,000 6,094E-03 8,962E-03 ! regulation of bone mineralization GO:0030500 49 23 0,000 6,094E-03 8,957E-03 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 6,094E-03 8,951E-03 ! hormone transport GO:0009914 40 23 0,000 6,094E-03 8,946E-03 ! cell-cell recognition GO:0009988 25 23 0,000 6,094E-03 8,94E-03 ! negative regulation of cytokine production GO:0001818 40 23 0,000 6,094E-03 8,935E-03 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 6,094E-03 8,929E-03 ! negative regulation of catabolic process GO:0009895 50 23 0,000 6,094E-03 8,924E-03 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 6,094E-03 8,918E-03 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 6,094E-03 8,913E-03 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 6,358E-03 9,294E-03 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 6,358E-03 9,288E-03 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 6,358E-03 9,283E-03 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 6,358E-03 9,277E-03 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 6,358E-03 9,271E-03 ! regulation of transmembrane transport GO:0034762 38 24 0,000 6,358E-03 9,266E-03 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 6,358E-03 9,26E-03 ! vesicle docking GO:0048278 47 24 0,000 6,358E-03 9,254E-03 ! spinal cord development GO:0021510 47 24 0,000 6,358E-03 9,249E-03 ! vacuole organization GO:0007033 43 24 0,000 6,358E-03 9,243E-03 ! multicellular organismal response to stress GO:0033555 49 24 0,000 6,358E-03 9,238E-03 ! digestive system process GO:0022600 39 24 0,000 6,358E-03 9,232E-03 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 6,358E-03 9,227E-03 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 6,358E-03 9,221E-03 ! regulation of behavior GO:0050795 43 24 0,000 6,358E-03 9,215E-03 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 6,358E-03 9,21E-03 ! lymphocyte proliferation GO:0046651 48 24 0,000 6,358E-03 9,204E-03 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 6,358E-03 9,199E-03 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 6,358E-03 9,193E-03 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 6,358E-03 9,188E-03 ! membrane depolarization GO:0051899 39 24 0,000 6,358E-03 9,182E-03 ! pallium development GO:0021543 49 24 0,000 6,358E-03 9,177E-03 ! pentose metabolic process GO:0019321 35 24 0,000 6,358E-03 9,171E-03 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 6,358E-03 9,166E-03 ! leukocyte homeostasis GO:0001776 44 24 0,000 6,358E-03 9,16E-03 ! cellular alkene metabolic process GO:0043449 43 24 0,000 6,358E-03 9,155E-03 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 6,358E-03 9,149E-03 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 6,358E-03 9,144E-03 ! porphyrin metabolic process GO:0006778 46 24 0,000 6,358E-03 9,138E-03 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 6,358E-03 9,133E-03 ! regulation of multi-organism process GO:0043900 36 24 0,000 6,358E-03 9,127E-03 ! regulation of amine transport GO:0051952 40 24 0,000 6,358E-03 9,122E-03 ! protein tetramerization GO:0051262 52 24 0,000 6,358E-03 9,117E-03 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 6,622E-03 9,49E-03 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 6,622E-03 9,484E-03 ! myelination GO:0042552 45 25 0,000 6,622E-03 9,478E-03 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 6,622E-03 9,473E-03 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 6,622E-03 9,467E-03 ! phototransduction GO:0007602 33 25 0,000 6,622E-03 9,462E-03 ! protein amino acid alkylation GO:0008213 53 25 0,000 6,622E-03 9,456E-03 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 6,622E-03 9,45E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 6,622E-03 9,445E-03 ! sperm motility GO:0030317 31 25 0,000 6,622E-03 9,439E-03 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 6,622E-03 9,434E-03 ! negative regulation of DNA replication GO:0008156 42 25 0,000 6,622E-03 9,428E-03 ! receptor metabolic process GO:0043112 46 25 0,000 6,622E-03 9,422E-03 ! chromosome condensation GO:0030261 45 25 0,000 6,622E-03 9,417E-03 ! response to starvation GO:0042594 42 25 0,000 6,622E-03 9,411E-03 ! osteoblast differentiation GO:0001649 60 25 0,000 6,622E-03 9,406E-03 ! neural crest cell development GO:0014032 54 25 0,000 6,622E-03 9,4E-03 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 6,622E-03 9,395E-03 ! negative regulation of cell development GO:0010721 73 25 0,000 6,622E-03 9,389E-03 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 6,622E-03 9,384E-03 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 6,622E-03 9,378E-03 ! interaction with host GO:0051701 62 25 0,000 6,622E-03 9,372E-03 ! regulation of biomineral formation GO:0070167 51 25 0,000 6,622E-03 9,367E-03 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 6,622E-03 9,361E-03 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 6,622E-03 9,356E-03 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 6,622E-03 9,35E-03 ! immunoglobulin production GO:0002377 55 25 0,000 6,622E-03 9,345E-03 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 6,622E-03 9,34E-03 ! positive regulation of protein secretion GO:0050714 36 25 0,000 6,622E-03 9,334E-03 ! regulation of blood coagulation GO:0030193 40 25 0,000 6,622E-03 9,329E-03 ! cellular response to nutrient levels GO:0031669 41 25 0,000 6,622E-03 9,323E-03 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 6,622E-03 9,318E-03 ! telomere organization GO:0032200 43 25 0,000 6,622E-03 9,312E-03 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 6,622E-03 9,307E-03 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 6,622E-03 9,301E-03 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 6,886E-03 9,667E-03 ! embryonic pattern specification GO:0009880 44 26 0,000 6,886E-03 9,661E-03 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 6,886E-03 9,655E-03 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 6,886E-03 9,65E-03 ! initiation of viral infection GO:0019059 57 26 0,000 6,886E-03 9,644E-03 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 6,886E-03 9,639E-03 ! pyruvate metabolic process GO:0006090 38 26 0,000 6,886E-03 9,633E-03 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 6,886E-03 9,627E-03 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 6,886E-03 9,622E-03 ! molting cycle process GO:0022404 50 26 0,000 6,886E-03 9,616E-03 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 6,886E-03 9,611E-03 ! macromolecular complex disassembly GO:0032984 53 26 0,000 6,886E-03 9,605E-03 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 6,886E-03 9,599E-03 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 6,886E-03 9,594E-03 ! microtubule organizing center organization GO:0031023 39 26 0,000 6,886E-03 9,588E-03 GO:0051297|centrosome organization, ! insulin receptor signaling pathway GO:0008286 64 26 0,000 6,886E-03 9,583E-03 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 6,886E-03 9,577E-03 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 6,886E-03 9,572E-03 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 6,886E-03 9,566E-03 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 6,886E-03 9,561E-03 ! cellular response to oxidative stress GO:0034599 39 26 0,000 6,886E-03 9,555E-03 ! response to estradiol stimulus GO:0032355 40 26 0,000 6,886E-03 9,55E-03 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 6,886E-03 9,544E-03 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 6,886E-03 9,539E-03 ! positive regulation of nuclear division GO:0051785 40 26 0,000 6,886E-03 9,533E-03 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 6,886E-03 9,528E-03 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 6,886E-03 9,522E-03 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 6,886E-03 9,517E-03 ! blastocyst development GO:0001824 49 26 0,000 6,886E-03 9,511E-03 ! leukocyte proliferation GO:0070661 52 26 0,000 6,886E-03 9,506E-03 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 6,886E-03 9,5E-03 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 6,886E-03 9,495E-03 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 7,15E-03 9,853E-03 ! neuron fate commitment GO:0048663 48 27 0,000 7,15E-03 9,848E-03 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 7,15E-03 9,842E-03 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 7,15E-03 9,836E-03 ! iron ion transport GO:0006826 59 27 0,000 7,15E-03 9,831E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 7,15E-03 9,825E-03 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 7,15E-03 9,82E-03 ! protein amino acid acylation GO:0043543 55 27 0,000 7,15E-03 9,814E-03 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 7,15E-03 9,808E-03 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 7,15E-03 9,803E-03 ! positive regulation of innate immune response GO:0045089 43 27 0,000 7,15E-03 9,797E-03 ! mitochondrial membrane organization GO:0007006 57 27 0,000 7,15E-03 9,792E-03 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 7,15E-03 9,786E-03 ! autophagy GO:0006914 41 27 0,000 7,15E-03 9,78E-03 ! male gonad development GO:0008584 44 27 0,000 7,15E-03 9,775E-03 ! response to toxin GO:0009636 47 27 0,000 7,15E-03 9,769E-03 ! primary neural tube formation GO:0014020 51 27 0,000 7,15E-03 9,764E-03 ! base-excision repair GO:0006284 41 27 0,000 7,15E-03 9,758E-03 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 7,15E-03 9,753E-03 ! glycolipid metabolic process GO:0006664 47 27 0,000 7,15E-03 9,747E-03 ! regulation of chromosome organization GO:0033044 42 27 0,000 7,15E-03 9,742E-03 ! glutathione metabolic process GO:0006749 39 27 0,000 7,15E-03 9,736E-03 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 7,15E-03 9,731E-03 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 7,15E-03 9,725E-03 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 7,15E-03 9,72E-03 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 7,15E-03 9,714E-03 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 7,414E-03 0,01006713 ! circadian rhythm GO:0007623 50 28 0,000 7,414E-03 0,01006145 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 7,414E-03 0,01005578 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 7,414E-03 0,01005012 ! negative regulation of protein modification process GO:0031400 60 28 0,000 7,414E-03 0,01004446 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 7,414E-03 0,0100388 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 7,414E-03 0,01003316 ! vitamin biosynthetic process GO:0009110 39 28 0,000 7,414E-03 0,01002752 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 7,414E-03 0,01002188 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 7,414E-03 0,01001626 ! synaptogenesis GO:0007416 42 28 0,000 7,414E-03 0,01001064 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 7,414E-03 0,01000502 ! lipid oxidation GO:0034440 43 28 0,000 7,414E-03 9,999E-03 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 7,414E-03 9,994E-03 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 7,414E-03 9,988E-03 ! translational initiation GO:0006413 65 29 0,000 7,678E-03 0,01033795 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 7,678E-03 0,01033217 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 7,678E-03 0,01032639 ! regulation of pH GO:0006885 43 29 0,000 7,678E-03 0,01032062 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 7,678E-03 0,01031486 ! amino sugar metabolic process GO:0006040 38 29 0,000 7,678E-03 0,0103091 ! catechol metabolic process GO:0009712 54 29 0,000 7,678E-03 0,01030335 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 7,678E-03 0,01029761 ! respiratory gaseous exchange GO:0007585 57 29 0,000 7,678E-03 0,01029187 ! regulation of peptide secretion GO:0002791 47 29 0,000 7,678E-03 0,01028614 ! immune response-activating signal transduction GO:0002757 47 29 0,000 7,678E-03 0,01028042 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 7,678E-03 0,0102747 ! response to organic cyclic substance GO:0014070 55 29 0,000 7,678E-03 0,01026899 ! cell fate determination GO:0001709 60 29 0,000 7,678E-03 0,01026329 ! sterol biosynthetic process GO:0016126 52 29 0,000 7,678E-03 0,01025759 ! detection of light stimulus GO:0009583 38 29 0,000 7,678E-03 0,01025189 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 7,678E-03 0,01024621 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 7,678E-03 0,01024053 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 7,678E-03 0,01023486 ! tissue homeostasis GO:0001894 48 29 0,000 7,678E-03 0,01022919 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 7,678E-03 0,01022353 ! phenol metabolic process GO:0018958 55 30 0,000 7,942E-03 0,01056899 ! zinc ion transport GO:0006829 45 30 0,000 7,942E-03 0,01056314 ! membrane docking GO:0022406 61 30 0,000 7,942E-03 0,01055731 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 7,942E-03 0,01055148 ! cell junction assembly GO:0034329 78 30 0,000 7,942E-03 0,01054565 ! regulation of innate immune response GO:0045088 51 30 0,000 7,942E-03 0,01053984 ! acute-phase response GO:0006953 49 30 0,000 7,942E-03 0,01053403 ! myofibril assembly GO:0030239 47 30 0,000 7,942E-03 0,01052822 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 7,942E-03 0,01052243 ! determination of left/right symmetry GO:0007368 47 30 0,000 7,942E-03 0,01051663 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 7,942E-03 0,01051085 ! phospholipid transport GO:0015914 51 30 0,000 7,942E-03 0,01050507 ! ensheathment of neurons GO:0007272 57 30 0,000 7,942E-03 0,0104993 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 7,942E-03 0,01049353 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 7,942E-03 0,01048777 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 7,942E-03 0,01048202 ! neurotransmitter secretion GO:0007269 48 30 0,000 7,942E-03 0,01047627 ! eye morphogenesis GO:0048592 60 30 0,000 7,942E-03 0,01047053 ! regulation of B cell activation GO:0050864 50 30 0,000 7,942E-03 0,0104648 ! response to heat GO:0009408 50 30 0,000 7,942E-03 0,01045907 ! alkaloid metabolic process GO:0009820 53 31 0,000 8,206E-03 0,01080054 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 8,206E-03 0,01079464 ! mRNA export from nucleus GO:0006406 48 31 0,000 8,206E-03 0,01078874 ! determination of bilateral symmetry GO:0009855 49 31 0,000 8,206E-03 0,01078284 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 8,206E-03 0,01077696 ! inner ear morphogenesis GO:0042472 47 31 0,000 8,206E-03 0,01077108 ! cholesterol homeostasis GO:0042632 53 31 0,000 8,206E-03 0,01076521 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 8,206E-03 0,01075934 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 8,206E-03 0,01075348 ! ovulation cycle process GO:0022602 49 31 0,000 8,206E-03 0,01074763 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 8,206E-03 0,01074178 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 8,206E-03 0,01073594 ! peptide transport GO:0015833 55 31 0,000 8,206E-03 0,0107301 ! triglyceride metabolic process GO:0006641 43 31 0,000 8,206E-03 0,01072427 ! iron ion homeostasis GO:0055072 54 31 0,000 8,206E-03 0,01071845 ! erythrocyte differentiation GO:0030218 55 31 0,000 8,206E-03 0,01071264 ! mesoderm formation GO:0001707 69 31 0,000 8,206E-03 0,01070683 ! natural killer cell activation GO:0030101 45 31 0,000 8,206E-03 0,01070102 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 8,206E-03 0,01069523 ! fatty acid catabolic process GO:0009062 48 31 0,000 8,206E-03 0,01068944 ! myeloid leukocyte activation GO:0002274 49 31 0,000 8,206E-03 0,01068365 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 8,206E-03 0,01067787 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 8,206E-03 0,0106721 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 8,47E-03 0,01100913 ! response to hydrogen peroxide GO:0042542 50 32 0,000 8,47E-03 0,01100319 ! proteoglycan metabolic process GO:0006029 63 32 0,000 8,47E-03 0,01099725 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 8,47E-03 0,01099132 ! cholesterol transport GO:0030301 56 32 0,000 8,47E-03 0,01098539 ! GPI anchor metabolic process GO:0006505 56 32 0,000 8,47E-03 0,01097947 ! spliceosome assembly GO:0000245 67 32 0,000 8,47E-03 0,01097356 ! spindle organization GO:0007051 46 32 0,000 8,47E-03 0,01096766 ! pigment biosynthetic process GO:0046148 66 32 0,000 8,47E-03 0,01096176 ! metanephros development GO:0001656 74 32 0,000 8,47E-03 0,01095586 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 8,47E-03 0,01094998 ! response to ionizing radiation GO:0010212 65 32 0,000 8,47E-03 0,01094409 ! response to mechanical stimulus GO:0009612 57 32 0,000 8,47E-03 0,01093822 ! regulation of axonogenesis GO:0050770 75 32 0,000 8,47E-03 0,01093235 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 8,47E-03 0,01092649 ! muscle cell development GO:0055001 49 32 0,000 8,47E-03 0,01092063 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 8,47E-03 0,01091479 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 8,47E-03 0,01090894 ! hexose biosynthetic process GO:0019319 48 32 0,000 8,47E-03 0,01090311 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 8,47E-03 0,01089728 ! ovulation cycle GO:0042698 51 32 0,000 8,47E-03 0,01089145 ! peripheral nervous system development GO:0007422 64 32 0,000 8,47E-03 0,01088563 ! BMP signaling pathway GO:0030509 64 32 0,000 8,47E-03 0,01087982 ! hindbrain development GO:0030902 61 32 0,000 8,47E-03 0,01087402 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 8,47E-03 0,01086822 ! regulation of calcium ion transport GO:0051924 53 32 0,000 8,47E-03 0,01086242 ! positive regulation of catabolic process GO:0009896 64 32 0,000 8,47E-03 0,01085664 ! gene silencing GO:0016458 65 32 0,000 8,47E-03 0,01085085 ! DNA damage checkpoint GO:0000077 71 33 0,000 8,733E-03 0,01118269 ! post-embryonic development GO:0009791 69 33 0,000 8,733E-03 0,01117674 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 8,733E-03 0,0111708 ! protein targeting to membrane GO:0006612 68 33 0,000 8,733E-03 0,01116486 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 8,733E-03 0,01115893 ! ceramide metabolic process GO:0006672 64 33 0,000 8,733E-03 0,01115301 ! formation of primary germ layer GO:0001704 72 33 0,000 8,733E-03 0,01114709 ! cell fate specification GO:0001708 52 33 0,000 8,733E-03 0,01114118 ! sterol transport GO:0015918 57 33 0,000 8,733E-03 0,01113528 ! leukocyte chemotaxis GO:0030595 50 33 0,000 8,733E-03 0,01112938 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 8,733E-03 0,01112349 ! adult locomotory behavior GO:0008344 59 33 0,000 8,733E-03 0,0111176 ! negative regulation of protein transport GO:0051224 69 33 0,000 8,733E-03 0,01111173 ! establishment of vesicle localization GO:0051650 61 33 0,000 8,733E-03 0,01110585 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 8,997E-03 0,01143502 ! glial cell differentiation GO:0010001 63 34 0,000 8,997E-03 0,01142898 ! xenobiotic metabolic process GO:0006805 51 34 0,000 8,997E-03 0,01142295 ! positive regulation of endocytosis GO:0045807 50 34 0,000 8,997E-03 0,01141693 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 8,997E-03 0,01141091 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 8,997E-03 0,0114049 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 8,997E-03 0,01139889 ! mesoderm morphogenesis GO:0048332 76 34 0,000 8,997E-03 0,01139289 ! mismatch repair GO:0006298 46 34 0,000 8,997E-03 0,0113869 ! spermatid development GO:0007286 63 34 0,000 8,997E-03 0,01138091 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 8,997E-03 0,01137493 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 8,997E-03 0,01136896 ! placenta development GO:0001890 53 34 0,000 8,997E-03 0,01136299 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 8,997E-03 0,01135703 ! regulation of muscle development GO:0048634 70 35 0,000 9,26E-03 0,01168357 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 9,26E-03 0,01167745 ! negative regulation of secretion GO:0051048 63 35 0,000 9,26E-03 0,01167133 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 9,26E-03 0,01166522 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 9,26E-03 0,01165911 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 9,26E-03 0,01165302 ! odontogenesis GO:0042476 66 35 0,000 9,26E-03 0,01164693 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 9,26E-03 0,01164084 ! female gonad development GO:0008585 58 35 0,000 9,26E-03 0,01163476 ! neutral lipid metabolic process GO:0006638 50 35 0,000 9,26E-03 0,01162869 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 9,26E-03 0,01162262 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 9,26E-03 0,01161656 ! calcium-mediated signaling GO:0019722 62 35 0,000 9,26E-03 0,01161051 ! cytokine production GO:0001816 59 35 0,000 9,26E-03 0,01160446 ! regulation of microtubule-based process GO:0032886 78 35 0,000 9,26E-03 0,01159842 ! neural tube formation GO:0001841 67 35 0,000 9,26E-03 0,01159239 ! vesicle localization GO:0051648 64 35 0,000 9,26E-03 0,01158636 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 9,524E-03 0,01190982 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 9,524E-03 0,01190363 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 9,524E-03 0,01189745 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 9,524E-03 0,01189128 ! cell junction organization GO:0034330 86 36 0,000 9,524E-03 0,01188511 ! sphingoid metabolic process GO:0046519 70 36 0,000 9,524E-03 0,01187895 ! maintenance of protein location in cell GO:0032507 86 36 0,000 9,524E-03 0,01187279 ! positive regulation of cell development GO:0010720 80 36 0,000 9,524E-03 0,01186665 ! DNA integrity checkpoint GO:0031570 75 36 0,000 9,524E-03 0,0118605 ! regulation of proteolysis GO:0030162 72 36 0,000 9,524E-03 0,01185437 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 9,524E-03 0,01184824 ! hormone biosynthetic process GO:0042446 57 36 0,000 9,524E-03 0,01184212 ! aerobic respiration GO:0009060 55 36 0,000 9,524E-03 0,011836 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 9,524E-03 0,01182989 ! embryonic organ development GO:0048568 57 36 0,000 9,524E-03 0,01182378 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 9,524E-03 0,01181769 ! negative regulation of cell activation GO:0050866 65 36 0,000 9,524E-03 0,01181159 ! RNA export from nucleus GO:0006405 56 37 0,000 9,787E-03 0,01213203 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 9,787E-03 0,01212578 ! meiosis I GO:0007127 65 37 0,000 9,787E-03 0,01211954 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 9,787E-03 0,01211331 ! sister chromatid segregation GO:0000819 58 37 0,000 9,787E-03 0,01210708 ! actomyosin structure organization GO:0031032 62 37 0,000 9,787E-03 0,01210086 ! organic anion transport GO:0015711 68 37 0,000 9,787E-03 0,01209464 ! tissue remodeling GO:0048771 76 37 0,000 9,787E-03 0,01208844 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 9,787E-03 0,01208223 ! negative regulation of DNA binding GO:0043392 68 37 0,000 9,787E-03 0,01207604 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 9,787E-03 0,01206985 ! glycerol ether metabolic process GO:0006662 53 37 0,000 9,787E-03 0,01206366 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 9,787E-03 0,01205749 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 9,787E-03 0,01205132 ! glycogen metabolic process GO:0005977 61 37 0,000 9,787E-03 0,01204515 ! pigment metabolic process GO:0042440 80 37 0,000 9,787E-03 0,01203899 ! spermatid differentiation GO:0048515 66 37 0,000 9,787E-03 0,01203284 ! cellular response to insulin stimulus GO:0032869 82 37 0,000 9,787E-03 0,0120267 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,01005067 0,012344 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,01005067 0,01233771 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,01005067 0,01233141 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,01005067 0,01232513 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,01005067 0,01231885 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,01005067 0,01231258 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,01005067 0,01230631 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,01005067 0,01230005 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,01005067 0,0122938 ! lipid homeostasis GO:0055088 67 38 0,000 0,01005067 0,01228755 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,01005067 0,01228131 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,01005067 0,01227508 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,01005067 0,01226885 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,01005067 0,01226263 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,01005067 0,01225641 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,01005067 0,0122502 ! glucan metabolic process GO:0044042 62 38 0,000 0,01005067 0,012244 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,01031396 0,01255839 ! mammary gland development GO:0030879 86 39 0,000 0,01031396 0,01255204 ! learning GO:0007612 77 39 0,000 0,01031396 0,0125457 ! ear morphogenesis GO:0042471 60 39 0,000 0,01031396 0,01253936 ! organic ether metabolic process GO:0018904 55 39 0,000 0,01031396 0,01253302 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,01031396 0,0125267 ! segmentation GO:0035282 67 39 0,000 0,01031396 0,01252038 ! ion transmembrane transport GO:0034220 66 39 0,000 0,01031396 0,01251406 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,01031396 0,01250775 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,01031396 0,01250145 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,01031396 0,01249516 ! RNA modification GO:0009451 57 39 0,000 0,01031396 0,01248887 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,01031396 0,01248259 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,01057719 0,01279473 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,01057719 0,0127883 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,01057719 0,01278188 ! feeding behavior GO:0007631 59 40 0,000 0,01057719 0,01277546 ! negative regulation of binding GO:0051100 72 40 0,000 0,01057719 0,01276905 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,01057719 0,01276265 ! mesenchymal cell development GO:0014031 87 40 0,000 0,01057719 0,01275625 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,01057719 0,01274986 ! maintenance of protein location GO:0045185 91 40 0,000 0,01057719 0,01274348 ! cytokinesis GO:0000910 72 40 0,000 0,01057719 0,0127371 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,01084036 0,01304748 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,01084036 0,01304096 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,01084036 0,01303444 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,01084036 0,01302793 ! gliogenesis GO:0042063 88 41 0,000 0,01084036 0,01302142 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,01084036 0,01301493 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,01084036 0,01300843 ! T cell differentiation GO:0030217 81 41 0,000 0,01084036 0,01300195 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,01084036 0,01299547 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,01084036 0,012989 ! female gamete generation GO:0007292 61 41 0,000 0,01084036 0,01298253 ! polyol metabolic process GO:0019751 66 41 0,000 0,01084036 0,01297607 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,01084036 0,01296962 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,01110347 0,01327781 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,01110347 0,01327121 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,01110347 0,01326462 ! regulation of tube size GO:0035150 71 42 0,000 0,01110347 0,01325804 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,01110347 0,01325146 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,01110347 0,01324489 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,01110347 0,01323833 ! regulation of intracellular protein transport GO:0033157 80 42 0,000 0,01110347 0,01323177 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,01110347 0,01322522 ! neuron migration GO:0001764 79 42 0,000 0,01110347 0,01321868 ! regulation of protein secretion GO:0050708 71 42 0,000 0,01110347 0,01321214 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,01110347 0,01320561 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,01136652 0,01351178 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,01136652 0,01350511 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,01136652 0,01349844 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,01136652 0,01349178 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,01136652 0,01348513 ! glucose transport GO:0015758 65 43 0,000 0,01136652 0,01347848 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,01136652 0,01347184 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,01136652 0,01346521 ! neural tube development GO:0021915 77 43 0,000 0,01136652 0,01345859 ! regulation of epithelial cell proliferation GO:0050678 111 43 0,000 0,01136652 0,01345197 ! striated muscle contraction GO:0006941 77 43 0,000 0,01136652 0,01344535 ! phagocytosis GO:0006909 90 43 0,000 0,01136652 0,01343874 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,01136652 0,01343214 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,01162951 0,01373618 ! hexose transport GO:0008645 67 44 0,000 0,01162951 0,01372944 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,01162951 0,0137227 ! male sex differentiation GO:0046661 76 44 0,000 0,01162951 0,01371598 ! double-strand break repair GO:0006302 81 44 0,000 0,01162951 0,01370926 ! biopolymer methylation GO:0043414 84 44 0,000 0,01162951 0,01370254 ! B cell differentiation GO:0030183 107 44 0,000 0,01162951 0,01369584 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,01162951 0,01368913 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,01162951 0,01368244 ! developmental growth GO:0048589 82 44 0,000 0,01162951 0,01367575 ! maintenance of location in cell GO:0051651 97 44 0,000 0,01162951 0,01366907 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,01189243 0,01397128 ! glycolysis GO:0006096 65 45 0,000 0,01189243 0,01396447 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,01189243 0,01395765 ! leukocyte migration GO:0050900 68 45 0,000 0,01189243 0,01395085 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,01189243 0,01394405 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,01189243 0,01393726 ! induction of apoptosis by intracellular signals GO:0008629 93 45 0,000 0,01189243 0,01393047 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,01189243 0,01392369 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,01189243 0,01391692 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,01189243 0,01391016 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,01189243 0,0139034 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,01189243 0,01389664 ! cell growth GO:0016049 84 45 0,000 0,01189243 0,0138899 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,0121553 0,01419003 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 0,000 0,0121553 0,01418314 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,0121553 0,01417627 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,0121553 0,0141694 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,0121553 0,01416254 ! pigmentation GO:0043473 100 46 0,000 0,0121553 0,01415568 ! response to insulin stimulus GO:0032868 95 46 0,000 0,0121553 0,01414884 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,0121553 0,01414199 ! positive regulation of defense response GO:0031349 76 47 0,000 0,0124181 0,01444077 ! endosome transport GO:0016197 108 47 0,000 0,0124181 0,01443379 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,0124181 0,01442682 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,0124181 0,01441986 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,0124181 0,0144129 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,0124181 0,01440595 ! JNK cascade GO:0007254 91 47 0,000 0,0124181 0,01439901 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,0124181 0,01439207 ! methylation GO:0032259 90 47 0,000 0,0124181 0,01438515 ! protein homooligomerization GO:0051260 76 47 0,000 0,0124181 0,01437822 ! mitochondrial transport GO:0006839 82 48 0,000 0,01268084 0,01467538 ! Notch signaling pathway GO:0007219 96 48 0,000 0,01268084 0,01466832 ! cellular component disassembly GO:0022411 86 48 0,000 0,01268084 0,01466127 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,01268084 0,01465423 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,01268084 0,01464719 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,01268084 0,01464017 ! activation of caspase activity GO:0006919 84 48 0,000 0,01268084 0,01463314 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,01268084 0,01462613 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,01268084 0,01461912 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,01268084 0,01461212 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,01268084 0,01460512 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,01294352 0,01490053 ! regulation of action potential GO:0001508 95 49 0,000 0,01294352 0,01489341 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,01294352 0,01488629 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,01294352 0,01487918 ! regulation of ion transport GO:0043269 77 49 0,000 0,01294352 0,01487207 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,01294352 0,01486497 ! peptide metabolic process GO:0006518 76 49 0,000 0,01294352 0,01485788 ! response to temperature stimulus GO:0009266 76 49 0,000 0,01294352 0,01485079 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,01294352 0,01484372 ! endocrine system development GO:0035270 104 49 0,000 0,01294352 0,01483664 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,01294352 0,01482958 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,01294352 0,01482252 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,01294352 0,01481547 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,01294352 0,01480842 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,01320614 0,0151017 ! neuromuscular process GO:0050905 99 50 0,000 0,01320614 0,01509453 ! regulation of ossification GO:0030278 117 50 0,000 0,01320614 0,01508736 ! inner ear development GO:0048839 79 50 0,000 0,01320614 0,0150802 ! histone modification GO:0016570 91 50 0,000 0,01320614 0,01507304 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,01320614 0,0150659 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,01320614 0,01505876 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,01320614 0,01505162 ! positive regulation of binding GO:0051099 78 51 0,000 0,0134687 0,01534361 ! viral infectious cycle GO:0019058 99 51 0,000 0,0134687 0,01533634 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,0134687 0,01532909 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,0134687 0,01532184 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,0134687 0,0153146 ! excretion GO:0007588 83 51 0,000 0,0134687 0,01530737 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,0134687 0,01530014 ! chromatin remodeling GO:0006338 109 51 0,000 0,0134687 0,01529292 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,0134687 0,0152857 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,0134687 0,0152785 ! vesicle organization GO:0016050 107 51 0,000 0,0134687 0,0152713 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,0134687 0,0152641 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 0,000 0,0134687 0,01525692 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,0134687 0,01524974 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,0137312 0,01553963 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,0137312 0,01553233 ! membrane fusion GO:0006944 110 52 0,000 0,0137312 0,01552503 ! positive regulation of growth GO:0045927 90 52 0,000 0,0137312 0,01551774 ! covalent chromatin modification GO:0016569 101 52 0,000 0,0137312 0,01551045 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,0137312 0,01550317 ! amino acid activation GO:0043038 92 52 0,000 0,0137312 0,0154959 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,0137312 0,01548864 ! synapse organization GO:0050808 85 52 0,000 0,0137312 0,01548138 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,01399363 0,01576988 ! RNA catabolic process GO:0006401 93 53 0,000 0,01399363 0,01576249 ! regulation of translational initiation GO:0006446 82 53 0,000 0,01399363 0,01575512 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,01399363 0,01574775 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,01399363 0,01574039 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,01399363 0,01573303 ! cell maturation GO:0048469 100 53 0,000 0,01399363 0,01572568 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,01399363 0,01571834 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,01399363 0,01571101 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,01425601 0,01599812 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,01425601 0,01599066 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,01425601 0,01598321 ! cell recognition GO:0008037 85 54 0,000 0,01425601 0,01597576 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,01425601 0,01596832 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,01425601 0,01596089 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,01425601 0,01595347 ! chloride transport GO:0006821 90 55 0,000 0,01451832 0,01623946 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,01451832 0,01623192 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,01451832 0,01622438 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,01451832 0,01621685 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,01451832 0,01620932 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,01451832 0,0162018 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,01451832 0,01619429 ! aging GO:0007568 103 55 0,000 0,01451832 0,01618679 ! gastrulation GO:0007369 112 55 0,000 0,01451832 0,01617929 ! heart morphogenesis GO:0003007 97 55 0,000 0,01451832 0,0161718 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,01451832 0,01616432 ! RNA elongation GO:0006354 79 55 0,000 0,01451832 0,01615684 ! nuclear export GO:0051168 97 55 0,000 0,01451832 0,01614937 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,01451832 0,01614191 ! regulation of actin filament length GO:0030832 105 56 0,000 0,01478058 0,0164259 ! sensory perception of smell GO:0007608 80 56 0,000 0,01478058 0,01641831 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,01478058 0,01641074 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,01478058 0,01640317 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,01478058 0,01639561 ! regulation of DNA replication GO:0006275 101 56 0,000 0,01478058 0,01638805 ! proton transport GO:0015992 94 56 0,000 0,01478058 0,0163805 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,01478058 0,01637296 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,01504277 0,01665573 ! muscle fiber development GO:0048747 112 57 0,000 0,01504277 0,01664807 ! positive regulation of cell migration GO:0030335 126 57 0,000 0,01504277 0,01664042 ! lipid modification GO:0030258 97 57 0,000 0,01504277 0,01663277 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,01504277 0,01662513 ! regulation of intracellular transport GO:0032386 101 57 0,000 0,01504277 0,01661749 ! maintenance of location GO:0051235 118 57 0,000 0,01504277 0,01660987 ! hydrogen transport GO:0006818 97 58 0,000 0,0153049 0,01689156 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,0153049 0,01688381 ! regulation of endocytosis GO:0030100 91 58 0,000 0,0153049 0,01687607 ! adult behavior GO:0030534 99 58 0,000 0,0153049 0,01686834 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,0153049 0,01686062 ! positive regulation of secretion GO:0051047 95 59 0,000 0,01556697 0,01714148 ! regulation of cellular component size GO:0032535 109 59 0,000 0,01556697 0,01713364 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,01556697 0,0171258 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,01556697 0,01711798 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,01556697 0,01711016 ! DNA catabolic process GO:0006308 86 59 0,000 0,01556697 0,01710234 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,01556697 0,01709454 ! establishment of organelle localization GO:0051656 109 59 0,000 0,01556697 0,01708674 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,01582898 0,0173664 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,01582898 0,01735849 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,01582898 0,01735058 ! regulation of heart contraction GO:0008016 110 60 0,000 0,01582898 0,01734268 ! camera-type eye development GO:0043010 116 60 0,000 0,01582898 0,01733479 ! protein amino acid autophosphorylation GO:0046777 141 60 0,000 0,01582898 0,0173269 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,01582898 0,01731902 ! kidney development GO:0001822 122 60 0,000 0,01582898 0,01731115 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,01609093 0,01758963 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,01609093 0,01758164 ! mesoderm development GO:0007498 119 61 0,000 0,01609093 0,01757366 ! tRNA processing GO:0008033 89 61 0,000 0,01609093 0,01756569 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,01609093 0,01755772 ! response to peptide hormone stimulus GO:0043434 122 61 0,000 0,01609093 0,01754976 ! ear development GO:0043583 103 62 0,000 0,01635281 0,01782731 ! viral reproductive process GO:0022415 126 62 0,000 0,01635281 0,01781924 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,01635281 0,01781117 ! gonad development GO:0008406 98 62 0,000 0,01635281 0,01780311 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,01635281 0,01779506 ! regulation of mitosis GO:0007088 105 63 0,000 0,01661464 0,0180718 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,01661464 0,01806363 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,01661464 0,01805548 ! detection of external stimulus GO:0009581 91 63 0,000 0,01661464 0,01804732 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,01661464 0,01803918 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,01661464 0,01803104 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,01687641 0,01830687 ! cell redox homeostasis GO:0045454 102 64 0,000 0,01687641 0,01829862 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,01687641 0,01829037 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,01687641 0,01828214 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,01687641 0,01827391 ! positive regulation of cell motion GO:0051272 146 64 0,000 0,01687641 0,01826569 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,01713811 0,0185406 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,01713811 0,01853227 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,01713811 0,01852394 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,01713811 0,01851562 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,01713811 0,01850731 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,01739975 0,01878143 ! actin filament organization GO:0007015 148 66 0,000 0,01739975 0,01877301 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,01739975 0,01876459 ! extracellular matrix organization GO:0030198 133 66 0,000 0,01739975 0,01875618 ! secondary metabolic process GO:0019748 116 66 0,000 0,01739975 0,01874778 ! developmental maturation GO:0021700 116 66 0,000 0,01739975 0,01873939 ! cell projection assembly GO:0030031 120 66 0,000 0,01739975 0,01873101 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,01766133 0,0190041 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,01766133 0,01899561 ! negative regulation of protein kinase activity GO:0006469 130 67 0,000 0,01766133 0,01898712 ! negative regulation of cell growth GO:0030308 132 67 0,000 0,01766133 0,01897864 ! activation of MAPK activity GO:0000187 115 67 0,000 0,01766133 0,01897017 ! lung development GO:0030324 144 67 0,000 0,01766133 0,0189617 ! chromosome segregation GO:0007059 113 67 0,000 0,01766133 0,01895324 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,01766133 0,01894479 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,01766133 0,01893635 ! hexose catabolic process GO:0019320 104 67 0,000 0,01766133 0,01892792 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,01766133 0,01891949 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,01766133 0,01891107 ! adaptive immune response GO:0002250 119 67 0,000 0,01766133 0,01890266 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,01766133 0,01889425 ! amino acid transport GO:0006865 125 68 0,000 0,01792286 0,01916551 ! negative regulation of kinase activity GO:0033673 131 68 0,000 0,01792286 0,01915699 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,01792286 0,01914849 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,01792286 0,01913999 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,01792286 0,01913149 ! viral reproduction GO:0016032 134 68 0,000 0,01792286 0,01912301 ! regulation of lipase activity GO:0060191 130 68 0,000 0,01792286 0,01911453 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,01792286 0,01910607 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,01818432 0,0193762 ! negative regulation of cell size GO:0045792 134 69 0,000 0,01818432 0,01936762 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,01818432 0,01935905 ! urogenital system development GO:0001655 137 69 0,000 0,01818432 0,01935049 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,01818432 0,01934194 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,01818432 0,01933339 ! antigen processing and presentation GO:0019882 104 69 0,000 0,01818432 0,01932485 ! appendage morphogenesis GO:0035107 135 70 0,000 0,01844571 0,01959399 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 0,000 0,01844571 0,01958534 ! amine catabolic process GO:0009310 117 71 0,000 0,01870705 0,01985407 ! reproductive structure development GO:0048608 113 71 0,000 0,01870705 0,01984531 ! appendage development GO:0048736 136 71 0,000 0,01870705 0,01983657 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,01870705 0,01982783 ! B cell activation GO:0042113 160 71 0,000 0,01870705 0,0198191 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,01870705 0,01981037 ! regulation of immune effector process GO:0002697 137 71 0,000 0,01870705 0,01980166 ! acute inflammatory response GO:0002526 113 72 0,000 0,01896833 0,02006939 ! regulation of caspase activity GO:0043281 122 72 0,000 0,01896833 0,02006057 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,01896833 0,02005176 ! carbohydrate transport GO:0008643 110 72 0,000 0,01896833 0,02004295 ! negative regulation of transferase activity GO:0051348 140 72 0,000 0,01896833 0,02003415 ! respiratory system development GO:0060541 153 72 0,000 0,01896833 0,02002536 ! learning or memory GO:0007611 147 73 0,000 0,01922955 0,02029223 ! regulation of blood pressure GO:0008217 125 73 0,000 0,01922955 0,02028334 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,01922955 0,02027445 ! axon guidance GO:0007411 139 73 0,000 0,01922955 0,02026557 ! fertilization GO:0009566 90 73 0,000 0,01922955 0,02025669 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,0194907 0,02052281 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,0194907 0,02051384 ! neurotransmitter transport GO:0006836 123 74 0,000 0,0194907 0,02050487 ! meiosis GO:0007126 121 74 0,000 0,0194907 0,02049591 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,0194907 0,02048695 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,0194907 0,020478 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,0194907 0,02046907 ! regulation of endopeptidase activity GO:0052548 125 74 0,000 0,0194907 0,02046014 ! eye development GO:0001654 143 74 0,000 0,0194907 0,02045121 ! organelle localization GO:0051640 136 74 0,000 0,0194907 0,0204423 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,0197518 0,02070711 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,0197518 0,02069809 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,0197518 0,02068908 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,0197518 0,02068008 ! meiotic cell cycle GO:0051321 122 75 0,000 0,0197518 0,02067109 ! rhythmic process GO:0048511 128 75 0,000 0,0197518 0,0206621 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,0197518 0,02065312 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,02001283 0,02091697 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,02001283 0,02090789 ! defense response to bacterium GO:0042742 89 76 0,000 0,02001283 0,02089882 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,02001283 0,02088975 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,02001283 0,02088069 ! regulation of catabolic process GO:0009894 161 76 0,000 0,02001283 0,02087164 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,02027381 0,02113465 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,02027381 0,0211255 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,02027381 0,02111635 ! blood coagulation GO:0007596 146 78 0,000 0,02053472 0,02137885 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,02053472 0,02136961 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,02053472 0,02136037 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,02053472 0,02135114 ! protein oligomerization GO:0051259 139 78 0,000 0,02053472 0,02134191 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,02079557 0,02160369 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,02079557 0,02159436 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,02079557 0,02158505 ! regulation of peptidase activity GO:0052547 134 79 0,000 0,02079557 0,02157574 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,02079557 0,02156644 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,02105636 0,02182749 ! muscle cell differentiation GO:0042692 159 80 0,000 0,02105636 0,02181809 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,02105636 0,0218087 ! protein import into nucleus GO:0006606 158 80 0,000 0,02105636 0,02179931 ! inorganic anion transport GO:0015698 138 80 0,000 0,02105636 0,02178994 ! T cell activation GO:0042110 168 81 0,000 0,02131709 0,02205027 ! response to hypoxia GO:0001666 171 81 0,000 0,02131709 0,02204079 ! digestion GO:0007586 112 81 0,000 0,02131709 0,02203132 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,02131709 0,02202186 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,02131709 0,02201241 ! nuclear import GO:0051170 161 81 0,000 0,02131709 0,02200297 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,02131709 0,02199353 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,02157776 0,02225293 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,02157776 0,0222434 ! response to drug GO:0042493 143 82 0,000 0,02157776 0,02223387 ! response to nutrient GO:0007584 125 82 0,000 0,02157776 0,02222435 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,02157776 0,02221484 ! cellular response to hormone stimulus GO:0032870 167 82 0,000 0,02157776 0,02220534 ! response to oxygen levels GO:0070482 176 83 0,000 0,02183837 0,02246392 ! regulation of lyase activity GO:0051339 160 83 0,000 0,02183837 0,02245432 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,02209892 0,02271251 ! hemostasis GO:0007599 158 84 0,000 0,02209892 0,02270281 ! negative regulation of transport GO:0051051 153 84 0,000 0,02209892 0,02269312 ! negative regulation of growth GO:0045926 155 84 0,000 0,02209892 0,02268344 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,02209892 0,02267377 ! nucleosome assembly GO:0006334 122 85 0,000 0,0223594 0,02293125 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,0223594 0,02292148 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,0223594 0,02291172 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,02261983 0,02316871 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,02261983 0,02315885 ! chromatin assembly GO:0031497 124 86 0,000 0,02261983 0,023149 ! tube morphogenesis GO:0035239 176 86 0,000 0,02261983 0,02313916 ! mitochondrion organization GO:0007005 148 86 0,000 0,02261983 0,02312933 ! alcohol catabolic process GO:0046164 130 86 0,000 0,02261983 0,0231195 ! amine transport GO:0015837 155 86 0,000 0,02261983 0,02310969 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,02288019 0,02336577 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,02288019 0,02335585 ! protein localization in nucleus GO:0034504 176 87 0,000 0,02288019 0,02334595 ! regulation of protein transport GO:0051223 154 87 0,000 0,02288019 0,02333605 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 135 88 0,000 0,0231405 0,02359154 ! regulation of DNA binding GO:0051101 155 88 0,000 0,0231405 0,02358155 ! gland development GO:0048732 206 88 0,000 0,0231405 0,02357157 ! regulation of neurological system process GO:0031644 148 88 0,000 0,0231405 0,02356159 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,0231405 0,02355163 ! cellular defense response GO:0006968 114 89 0,000 0,02340074 0,02380642 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,02340074 0,02379636 ! regulation of cell adhesion GO:0030155 212 89 0,000 0,02340074 0,02378631 ! ossification GO:0001503 188 90 0,000 0,02366093 0,02404062 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,02366093 0,02403047 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,02366093 0,02402033 ! sex differentiation GO:0007548 145 90 0,000 0,02366093 0,0240102 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,02366093 0,02400008 ! bone development GO:0060348 189 91 0,000 0,02392105 0,02425371 ! sterol metabolic process GO:0016125 152 91 0,000 0,02392105 0,02424349 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,02392105 0,02423328 ! regulation of defense response GO:0031347 149 92 0,000 0,02418111 0,02448643 ! nucleosome organization GO:0034728 138 92 0,000 0,02418111 0,02447613 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,02418111 0,02446584 ! vitamin metabolic process GO:0006766 139 92 0,000 0,02418111 0,02445555 ! positive regulation of MAP kinase activity GO:0043406 160 93 0,000 0,02444111 0,02470812 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,02444111 0,02469774 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,02444111 0,02468737 ! regulation of membrane potential GO:0042391 164 93 0,000 0,02444111 0,02467701 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,02444111 0,02466666 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,02470106 0,02491855 ! female pregnancy GO:0007565 164 94 0,000 0,02470106 0,02490811 ! transcription initiation GO:0006352 153 94 0,000 0,02470106 0,02489767 ! regulation of T cell activation GO:0050863 158 94 0,000 0,02470106 0,02488724 ! forebrain development GO:0030900 188 95 0,000 0,02496094 0,02513856 ! leukocyte differentiation GO:0002521 202 96 0,000 0,02522076 0,0253896 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,02522076 0,02537898 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,02522076 0,02536837 ! positive regulation of immune response GO:0050778 156 96 0,000 0,02522076 0,02535777 ! detection of stimulus GO:0051606 151 96 0,000 0,02522076 0,02534718 ! regulation of DNA metabolic process GO:0051052 178 97 0,000 0,02548052 0,02559755 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,02548052 0,02558686 ! protein ubiquitination GO:0016567 217 97 0,000 0,02548052 0,02557619 ! hormone metabolic process GO:0042445 157 97 0,000 0,02548052 0,02556552 ! regulation of protein localization GO:0032880 176 97 0,000 0,02548052 0,02555486 ! response to virus GO:0009615 160 98 0,000 0,02574021 0,02580456 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,02574021 0,02579382 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,02574021 0,02578308 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,02599985 0,02603231 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,02599985 0,02602148 ! skeletal muscle tissue development GO:0007519 186 99 0,000 0,02599985 0,02601066 GO:0060538|skeletal muscle organ development, ! cell cycle arrest GO:0007050 213 100 0,000 0,02625943 0,02625943