pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-b2/out-0.05-06-0.01-300-run-b2//th1-pval-1e-01-06-th2-pval-1e-02-02-th3-pval-1e-01-01-run-b2/go_data/11168-0-real-Ivshina_GPL96-GPL97-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! meiosis I GO:0007127 65 37 2,000 4,84E-07 1,165E-03 ! positive regulation of cell cycle GO:0045787 89 48 2,000 1,074E-06 1,293E-03 ! response to UV GO:0009411 104 53 2,000 1,453E-06 1,166E-03 ! meiotic chromosome segregation GO:0045132 7 5 1,000 1,719E-06 1,034E-03 ! mitotic recombination GO:0006312 9 5 1,000 1,719E-06 8,27E-04 ! B cell homeostasis GO:0001782 13 5 1,000 1,719E-06 6,892E-04 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 2,000 1,814E-06 6,234E-04 ! neuron apoptosis GO:0051402 9 6 1,000 2,577E-06 7,752E-04 ! establishment of spindle localization GO:0051293 12 6 1,000 2,577E-06 6,89E-04 GO:0051653|spindle localization, ! negative regulation of B cell activation GO:0050869 13 6 1,000 2,577E-06 6,201E-04 ! induction of apoptosis by oxidative stress GO:0008631 8 7 1,000 3,607E-06 7,891E-04 ! meiosis GO:0007126 121 74 2,000 4,001E-06 8,022E-04 GO:0051327|M phase of meiotic cell cycle, ! meiotic cell cycle GO:0051321 122 75 2,000 4,167E-06 7,712E-04 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 4,809E-06 8,264E-04 ! regulation of activated T cell proliferation GO:0046006 16 9 1,000 6,181E-06 9,915E-04 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 7,725E-06 1,162E-03 ! lysogeny GO:0030069 21 11 1,000 9,439E-06 1,336E-03 GO:0019047|provirus integration, ! regulation of B cell proliferation GO:0030888 20 12 1,000 1,132E-05 1,514E-03 ! T cell homeostasis GO:0043029 25 12 1,000 1,132E-05 1,434E-03 ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 1,132E-05 1,362E-03 GO:0042130|negative regulation of T cell proliferation, ! double-strand break repair via homologous recombination GO:0000724 19 13 1,000 1,338E-05 1,533E-03 GO:0000725|recombinational repair, ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 1,561E-05 1,707E-03 ! lymphocyte homeostasis GO:0002260 30 15 1,000 1,8E-05 1,883E-03 ! induction of apoptosis via death domain receptors GO:0008625 20 16 1,000 2,057E-05 2,062E-03 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 2,057E-05 1,98E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! negative regulation of cell cycle process GO:0010948 32 17 1,000 2,331E-05 2,157E-03 ! DNA integration GO:0015074 29 17 1,000 2,331E-05 2,077E-03 ! DNA unwinding during replication GO:0006268 27 17 1,000 2,331E-05 2,003E-03 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 1,000 2,331E-05 1,934E-03 ! cellular response to unfolded protein GO:0034620 33 19 1,000 2,929E-05 2,349E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 3,254E-05 2,525E-03 ! DNA duplex unwinding GO:0032508 31 20 1,000 3,254E-05 2,446E-03 GO:0032392|DNA geometric change, ! negative regulation of T cell activation GO:0050868 40 20 1,000 3,254E-05 2,372E-03 ! reciprocal meiotic recombination GO:0007131 39 21 1,000 3,595E-05 2,544E-03 ! cell structure disassembly during apoptosis GO:0006921 30 21 1,000 3,595E-05 2,471E-03 ! apoptotic nuclear changes GO:0030262 32 22 1,000 3,954E-05 2,642E-03 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 1,000 3,954E-05 2,571E-03 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 1,000 4,722E-05 2,99E-03 ! leukocyte homeostasis GO:0001776 44 24 1,000 4,722E-05 2,913E-03 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 5,131E-05 3,086E-03 ! initiation of viral infection GO:0019059 57 26 1,000 5,557E-05 3,261E-03 ! positive regulation of nuclear division GO:0051785 40 26 1,000 5,557E-05 3,184E-03 GO:0045840|positive regulation of mitosis, ! fat cell differentiation GO:0045444 50 27 1,000 6E-05 3,357E-03 ! regulation of chromosome organization GO:0033044 42 27 1,000 6E-05 3,281E-03 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 6E-05 3,208E-03 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 6,46E-05 3,379E-03 ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 7,431E-05 3,804E-03 ! regulation of B cell activation GO:0050864 50 30 1,000 7,431E-05 3,725E-03 ! spindle organization GO:0007051 46 32 1,000 8,469E-05 4,158E-03 ! mitotic sister chromatid segregation GO:0000070 57 36 1,000 1,075E-04 5,171E-03 ! negative regulation of cell activation GO:0050866 65 36 1,000 1,075E-04 5,07E-03 ! sister chromatid segregation GO:0000819 58 37 1,000 1,136E-04 5,255E-03 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 1,199E-04 5,441E-03 ! nucleus organization GO:0006997 67 38 1,000 1,199E-04 5,34E-03 ! cytokinesis GO:0000910 72 40 1,000 1,329E-04 5,815E-03 ! regulation of T cell proliferation GO:0042129 71 41 1,000 1,397E-04 6,002E-03 ! keratinocyte differentiation GO:0030216 62 41 1,000 1,397E-04 5,897E-03 ! double-strand break repair GO:0006302 81 44 1,000 1,611E-04 6,681E-03 ! induction of apoptosis by intracellular signals GO:0008629 93 45 1,000 1,685E-04 6,871E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 1,000 1,761E-04 7,062E-03 ! epidermal cell differentiation GO:0009913 68 46 1,000 1,761E-04 6,947E-03 ! response to calcium ion GO:0051592 81 47 1,000 1,839E-04 7,137E-03 ! protein homooligomerization GO:0051260 76 47 1,000 1,839E-04 7,023E-03 ! cellular component disassembly GO:0022411 86 48 1,000 1,918E-04 7,212E-03 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 1,918E-04 7,101E-03 ! induction of apoptosis by extracellular signals GO:0008624 89 49 1,000 2E-04 7,29E-03 ! DNA-dependent DNA replication GO:0006261 74 49 1,000 2E-04 7,181E-03 ! negative regulation of immune system process GO:0002683 95 50 1,000 2,082E-04 7,368E-03 ! viral infectious cycle GO:0019058 99 51 1,000 2,167E-04 7,556E-03 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 2,167E-04 7,448E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! positive regulation of organelle organization GO:0010638 100 56 1,000 2,614E-04 8,859E-03 ! DNA catabolic process GO:0006308 86 59 1,000 2,902E-04 9,698E-03 ! establishment of organelle localization GO:0051656 109 59 1,000 2,902E-04 9,566E-03 ! viral reproductive process GO:0022415 126 62 1,000 3,205E-04 0,0104214 ! regulation of mitosis GO:0007088 105 63 1,000 3,31E-04 0,01061699 GO:0051783|regulation of nuclear division, ! negative regulation of protein kinase activity GO:0006469 130 67 1,000 3,743E-04 0,01184984 ! chromosome segregation GO:0007059 113 67 1,000 3,743E-04 0,01169595 ! homeostasis of number of cells GO:0048872 114 67 1,000 3,743E-04 0,011546 ! negative regulation of kinase activity GO:0033673 131 68 1,000 3,856E-04 0,01174244 ! viral reproduction GO:0016032 134 68 1,000 3,856E-04 0,01159566 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 3,856E-04 0,0114525 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 3,97E-04 0,0116477 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 1,000 4,322E-04 0,01252829 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 4,322E-04 0,01237914 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 1,000 4,322E-04 0,0122335 ! negative regulation of transferase activity GO:0051348 140 72 1,000 4,322E-04 0,01209125 ! organelle localization GO:0051640 136 74 1,000 4,565E-04 0,01262417 ! positive regulation of ligase activity GO:0051351 124 77 1,000 4,942E-04 0,01351051 ! negative regulation of organelle organization GO:0010639 161 78 1,000 5,07E-04 0,01370692 ! protein oligomerization GO:0051259 139 78 1,000 5,07E-04 0,01355462 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 1,000 5,201E-04 0,01375052 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 5,201E-04 0,01360106 ! response to metal ion GO:0010038 140 80 1,000 5,333E-04 0,01379645 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 5,466E-04 0,01399183 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of ligase activity GO:0051340 142 84 1,000 5,877E-04 0,01488483 ! response to unfolded protein GO:0006986 131 85 1,000 6,017E-04 0,01508105 ! response to inorganic substance GO:0010035 153 86 1,000 6,159E-04 0,01527722 ! mitochondrion organization GO:0007005 148 86 1,000 6,159E-04 0,01512133 ! positive regulation of protein modification process GO:0031401 136 88 1,000 6,448E-04 0,01566946 ! regulation of cell cycle process GO:0010564 149 90 1,000 6,742E-04 0,01622215 ! response to protein stimulus GO:0051789 149 91 1,000 6,892E-04 0,01641847 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 7,197E-04 0,01697577 GO:0010498|proteasomal protein catabolic process, ! regulation of T cell activation GO:0050863 158 94 1,000 7,351E-04 0,01717223 ! interphase of mitotic cell cycle GO:0051329 209 95 1,000 7,508E-04 0,01736863 ! regulation of DNA metabolic process GO:0051052 178 97 1,000 7,825E-04 0,01793038 ! interphase GO:0051325 213 98 1,000 7,986E-04 0,01812684 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 2,157E-03 0,0484917 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 2,157E-03 0,0480427 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 2,157E-03 0,04760194 ! positive regulation of helicase activity GO:0051096 11 5 0,000 2,157E-03 0,0471692 ! neuron fate determination GO:0048664 7 5 0,000 2,157E-03 0,04674425 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 2,157E-03 0,04632689 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 2,157E-03 0,04591692 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 2,157E-03 0,04551414 ! polyol transport GO:0015791 12 5 0,000 2,157E-03 0,04511836 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 2,157E-03 0,04472941 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 2,157E-03 0,04434711 ! response to superoxide GO:0000303 10 5 0,000 2,157E-03 0,04397128 ! negative regulation of bone resorption GO:0045779 10 5 0,000 2,157E-03 0,04360178 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 2,157E-03 0,04323843 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 2,157E-03 0,04288109 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 2,157E-03 0,0425296 ! female meiosis GO:0007143 7 5 0,000 2,157E-03 0,04218383 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 2,157E-03 0,04184364 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 2,157E-03 0,04150889 ! cobalt ion transport GO:0006824 11 5 0,000 2,157E-03 0,04117946 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 2,157E-03 0,04085521 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 2,157E-03 0,04053603 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 2,157E-03 0,0402218 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 2,157E-03 0,0399124 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 2,157E-03 0,03960772 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 2,157E-03 0,03930766 ! embryonic camera-type eye development GO:0031076 10 5 0,000 2,157E-03 0,03901212 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 2,157E-03 0,03872098 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 2,157E-03 0,03843416 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 2,157E-03 0,03815156 ! adaptation of signaling pathway GO:0022401 7 5 0,000 2,157E-03 0,03787308 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 2,157E-03 0,03759863 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 2,157E-03 0,03732814 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 2,157E-03 0,03706151 ! negative chemotaxis GO:0050919 14 5 0,000 2,157E-03 0,03679866 ! positive regulation of histone modification GO:0031058 5 5 0,000 2,157E-03 0,03653952 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 2,157E-03 0,036284 ! sensory perception of bitter taste GO:0050913 7 5 0,000 2,157E-03 0,03603202 ! behavioral response to pain GO:0048266 9 5 0,000 2,157E-03 0,03578353 ! clathrin coat assembly GO:0048268 14 5 0,000 2,157E-03 0,03553844 ! Notch receptor processing GO:0007220 8 5 0,000 2,157E-03 0,03529668 ! regulation of dopamine uptake GO:0051584 9 5 0,000 2,157E-03 0,03505819 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 2,157E-03 0,0348229 ! micturition GO:0060073 9 5 0,000 2,157E-03 0,03459074 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 2,157E-03 0,03436167 ! copulation GO:0007620 9 5 0,000 2,157E-03 0,0341356 ! glial cell fate commitment GO:0021781 13 5 0,000 2,157E-03 0,03391249 ! protein maturation by protein folding GO:0022417 13 5 0,000 2,157E-03 0,03369228 ! spermidine metabolic process GO:0008216 7 5 0,000 2,157E-03 0,03347491 ! regulation of potassium ion transport GO:0043266 10 5 0,000 2,157E-03 0,03326033 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 2,157E-03 0,03304848 ! apoptotic cell clearance GO:0043277 20 5 0,000 2,157E-03 0,03283931 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 2,157E-03 0,03263278 ! lipoprotein particle clearance GO:0034381 10 5 0,000 2,157E-03 0,03242882 ! grooming behavior GO:0007625 6 5 0,000 2,157E-03 0,0322274 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 2,157E-03 0,03202847 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 2,157E-03 0,03183197 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 2,157E-03 0,03163788 ! response to protozoan GO:0001562 10 5 0,000 2,157E-03 0,03144613 ! positive regulation of glycolysis GO:0045821 14 5 0,000 2,157E-03 0,0312567 ! lymph vessel development GO:0001945 10 5 0,000 2,157E-03 0,03106953 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 2,157E-03 0,03088459 ! endochondral ossification GO:0001958 16 5 0,000 2,157E-03 0,03070184 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 2,157E-03 0,03052124 ! parathyroid gland development GO:0060017 13 5 0,000 2,157E-03 0,03034276 ! anagen GO:0042640 6 5 0,000 2,157E-03 0,03016635 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 2,157E-03 0,02999197 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 2,157E-03 0,02981961 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 2,157E-03 0,02964921 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 2,157E-03 0,02948075 ! dorsal spinal cord development GO:0021516 7 5 0,000 2,157E-03 0,02931419 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 2,157E-03 0,0291495 ! sphingoid catabolic process GO:0046521 6 5 0,000 2,157E-03 0,02898666 ! skeletal myofibril assembly GO:0014866 10 5 0,000 2,157E-03 0,02882562 ! smooth muscle tissue development GO:0048745 28 5 0,000 2,157E-03 0,02866636 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 2,157E-03 0,02850885 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 2,157E-03 0,02835307 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 2,157E-03 0,02819898 ! cardiac muscle fiber development GO:0048739 10 5 0,000 2,157E-03 0,02804655 ! transepithelial chloride transport GO:0030321 9 5 0,000 2,157E-03 0,02789576 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 2,157E-03 0,02774659 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 2,157E-03 0,027599 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 2,157E-03 0,02745297 ! neutrophil mediated immunity GO:0002446 7 5 0,000 2,157E-03 0,02730848 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 2,157E-03 0,02716551 ! histidine catabolic process GO:0006548 6 5 0,000 2,157E-03 0,02702402 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 2,157E-03 0,026884 ! microvillus organization GO:0032528 7 5 0,000 2,157E-03 0,02674542 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 2,157E-03 0,02660826 ! L-serine biosynthetic process GO:0006564 6 5 0,000 2,157E-03 0,02647251 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 2,157E-03 0,02633813 ! tryptophan metabolic process GO:0006568 9 5 0,000 2,157E-03 0,02620511 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 2,157E-03 0,02607343 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 2,157E-03 0,02594306 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 2,157E-03 0,02581399 ! polyol catabolic process GO:0046174 7 5 0,000 2,157E-03 0,0256862 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 2,157E-03 0,02555966 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 2,157E-03 0,02543437 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 2,157E-03 0,0253103 ! muscle cell migration GO:0014812 8 5 0,000 2,157E-03 0,02518743 ! mitochondrial fission GO:0000266 8 5 0,000 2,157E-03 0,02506576 ! sister chromatid cohesion GO:0007062 12 5 0,000 2,157E-03 0,02494525 ! mRNA transcription GO:0009299 9 5 0,000 2,157E-03 0,02482589 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 2,157E-03 0,02470767 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 2,157E-03 0,02459058 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 2,157E-03 0,02447458 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 2,157E-03 0,02435968 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 2,157E-03 0,02424585 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 2,157E-03 0,02413308 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 2,157E-03 0,02402135 ! response to food GO:0032094 6 5 0,000 2,157E-03 0,02391065 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 2,157E-03 0,02380097 ! positive regulation of transporter activity GO:0032411 8 5 0,000 2,157E-03 0,02369229 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 2,157E-03 0,0235846 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 2,157E-03 0,02347788 ! paraxial mesoderm development GO:0048339 14 5 0,000 2,157E-03 0,02337212 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 2,157E-03 0,02326732 ! forebrain neuron development GO:0021884 13 5 0,000 2,157E-03 0,02316344 ! lipoprotein catabolic process GO:0042159 11 5 0,000 2,157E-03 0,0230605 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 2,157E-03 0,02295846 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 2,157E-03 0,02285732 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 2,157E-03 0,02275707 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 2,157E-03 0,02265769 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 2,157E-03 0,02255918 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 2,157E-03 0,02246152 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 2,157E-03 0,02236471 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 2,157E-03 0,02226872 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 2,157E-03 0,02217355 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 2,157E-03 0,0220792 ! basic amino acid transport GO:0015802 11 5 0,000 2,157E-03 0,02198564 ! cellular glucose homeostasis GO:0001678 5 5 0,000 2,157E-03 0,02189288 ! early endosome to late endosome transport GO:0045022 12 5 0,000 2,157E-03 0,02180089 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 2,157E-03 0,02170967 ! depyrimidination GO:0045008 10 5 0,000 2,157E-03 0,02161921 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 2,157E-03 0,02152951 ! regulation of centrosome cycle GO:0046605 7 5 0,000 2,157E-03 0,02144054 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 2,157E-03 0,02135231 ! zinc ion homeostasis GO:0055069 8 5 0,000 2,157E-03 0,0212648 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 2,157E-03 0,02117801 ! forebrain morphogenesis GO:0048853 13 5 0,000 2,157E-03 0,02109192 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 2,157E-03 0,02100652 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 2,157E-03 0,02092182 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 2,157E-03 0,0208378 ! peptidyl-arginine modification GO:0018195 9 5 0,000 2,157E-03 0,02075445 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 2,157E-03 0,02067176 ! positive regulation of organ growth GO:0046622 6 5 0,000 2,157E-03 0,02058973 ! response to arsenic GO:0046685 10 5 0,000 2,157E-03 0,02050835 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 2,157E-03 0,0204276 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 2,157E-03 0,0203475 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 2,157E-03 0,02026801 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 2,157E-03 0,02018915 ! response to cadmium ion GO:0046686 7 5 0,000 2,157E-03 0,0201109 ! bile acid biosynthetic process GO:0006699 6 5 0,000 2,157E-03 0,02003325 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 2,157E-03 0,0199562 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 2,157E-03 0,01987974 ! decidualization GO:0046697 11 5 0,000 2,157E-03 0,01980386 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 2,157E-03 0,01972856 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 2,157E-03 0,01965383 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 2,157E-03 0,01957967 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 2,157E-03 0,01950606 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 2,157E-03 0,019433 ! base conversion or substitution editing GO:0016553 5 5 0,000 2,157E-03 0,01936049 ! neural tube patterning GO:0021532 7 5 0,000 2,157E-03 0,01928852 ! embryonic cleavage GO:0040016 6 5 0,000 2,157E-03 0,01921708 ! peroxisome fission GO:0016559 5 5 0,000 2,157E-03 0,01914617 ! histone demethylation GO:0016577 10 5 0,000 2,157E-03 0,01907578 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 2,157E-03 0,0190059 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 2,157E-03 0,01893654 ! metaphase plate congression GO:0051310 7 5 0,000 2,157E-03 0,01886768 ! regulation of sterol transport GO:0032371 7 5 0,000 2,157E-03 0,01879932 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 2,157E-03 0,01873145 ! enteric nervous system development GO:0048484 8 5 0,000 2,157E-03 0,01866407 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 2,157E-03 0,01859717 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 2,157E-03 0,01853076 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 2,157E-03 0,01846481 ! muscle cell proliferation GO:0033002 11 5 0,000 2,157E-03 0,01839933 ! skeletal muscle regeneration GO:0043403 8 5 0,000 2,157E-03 0,01833432 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 2,157E-03 0,01826976 ! plasminogen activation GO:0031639 5 5 0,000 2,157E-03 0,01820565 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 2,157E-03 0,018142 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 2,157E-03 0,01807879 ! metaphase GO:0051323 8 5 0,000 2,157E-03 0,01801601 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 2,157E-03 0,01795367 ! cellular response to nutrient GO:0031670 8 5 0,000 2,157E-03 0,01789176 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 2,157E-03 0,01783028 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 2,157E-03 0,01776922 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 2,157E-03 0,01770857 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 2,157E-03 0,01764834 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 2,157E-03 0,01758851 ! response to redox state GO:0051775 5 5 0,000 2,157E-03 0,01752909 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 2,157E-03 0,01747007 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 2,157E-03 0,01741145 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 2,157E-03 0,01735322 ! regulation of telomerase activity GO:0051972 6 5 0,000 2,157E-03 0,01729537 ! galactolipid metabolic process GO:0019374 7 5 0,000 2,157E-03 0,01723791 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 2,157E-03 0,01718083 ! porphyrin catabolic process GO:0006787 12 5 0,000 2,157E-03 0,01712413 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 2,157E-03 0,0170678 ! striatum development GO:0021756 9 5 0,000 2,157E-03 0,01701184 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 2,157E-03 0,01695625 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 2,157E-03 0,01690101 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 2,157E-03 0,01684614 ! glial cell migration GO:0008347 11 5 0,000 2,157E-03 0,01679162 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 2,157E-03 0,01673746 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 2,157E-03 0,01668364 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 2,157E-03 0,01663017 ! somatic stem cell maintenance GO:0035019 15 5 0,000 2,157E-03 0,01657703 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 2,157E-03 0,01652424 ! negative regulation of lipase activity GO:0060192 8 5 0,000 2,157E-03 0,01647178 ! neuroprotection GO:0043526 6 5 0,000 2,157E-03 0,01641966 ! neural plate development GO:0001840 8 5 0,000 2,157E-03 0,01636786 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 2,157E-03 0,01631639 ! regulation of sensory perception GO:0051931 7 5 0,000 2,157E-03 0,01626524 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 2,157E-03 0,01621441 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 2,157E-03 0,0161639 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 2,157E-03 0,0161137 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 2,157E-03 0,01606381 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 2,157E-03 0,01601423 ! sequestering of calcium ion GO:0051208 7 5 0,000 2,157E-03 0,01596496 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 2,157E-03 0,01591599 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 2,157E-03 0,01586731 ! spindle assembly GO:0051225 6 5 0,000 2,157E-03 0,01581894 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 2,157E-03 0,01577086 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 2,157E-03 0,01572307 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 2,157E-03 0,01567556 ! drug metabolic process GO:0017144 6 5 0,000 2,157E-03 0,01562835 ! stem cell division GO:0017145 11 5 0,000 2,157E-03 0,01558142 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 2,157E-03 0,01553477 ! organ regeneration GO:0031100 7 5 0,000 2,157E-03 0,01548839 ! carnitine metabolic process GO:0009437 7 5 0,000 2,157E-03 0,0154423 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 2,157E-03 0,01539647 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 2,157E-03 0,01535092 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 2,587E-03 0,01836311 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 2,587E-03 0,0183091 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 2,587E-03 0,01825541 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 2,587E-03 0,01820203 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 2,587E-03 0,01814896 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 2,587E-03 0,0180962 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 2,587E-03 0,01804375 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 2,587E-03 0,0179916 ! sleep GO:0030431 13 6 0,000 2,587E-03 0,01793975 ! response to oxygen radical GO:0000305 11 6 0,000 2,587E-03 0,0178882 ! positive regulation of axon extension GO:0045773 11 6 0,000 2,587E-03 0,01783694 ! myoblast cell fate commitment GO:0048625 16 6 0,000 2,587E-03 0,01778598 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 2,587E-03 0,01773531 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 2,587E-03 0,01768493 ! regulation of interferon-beta production GO:0032648 8 6 0,000 2,587E-03 0,01763483 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 2,587E-03 0,01758501 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 2,587E-03 0,01753548 ! forebrain regionalization GO:0021871 8 6 0,000 2,587E-03 0,01748622 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 2,587E-03 0,01743724 ! male meiosis GO:0007140 7 6 0,000 2,587E-03 0,01738853 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 2,587E-03 0,01734009 ! response to zinc ion GO:0010043 9 6 0,000 2,587E-03 0,01729193 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 2,587E-03 0,01724403 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 2,587E-03 0,01719639 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 2,587E-03 0,01714902 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 2,587E-03 0,01710191 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 2,587E-03 0,01705505 ! malate metabolic process GO:0006108 11 6 0,000 2,587E-03 0,01700845 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 2,587E-03 0,01696211 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 2,587E-03 0,01691602 ! protein refolding GO:0042026 15 6 0,000 2,587E-03 0,01687017 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 2,587E-03 0,01682458 ! opsonization GO:0008228 8 6 0,000 2,587E-03 0,01677923 ! mating behavior GO:0007617 7 6 0,000 2,587E-03 0,01673412 ! neuron remodeling GO:0016322 15 6 0,000 2,587E-03 0,01668926 ! erythrocyte maturation GO:0043249 7 6 0,000 2,587E-03 0,01664464 ! embryonic hemopoiesis GO:0035162 14 6 0,000 2,587E-03 0,01660025 ! equilibrioception GO:0050957 14 6 0,000 2,587E-03 0,0165561 ! protein amino acid dealkylation GO:0008214 12 6 0,000 2,587E-03 0,01651218 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 2,587E-03 0,0164685 ! photoreceptor cell development GO:0042461 10 6 0,000 2,587E-03 0,01642505 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 2,587E-03 0,01638183 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 2,587E-03 0,01633883 ! response to interferon-gamma GO:0034341 15 6 0,000 2,587E-03 0,01629606 ! toxin metabolic process GO:0009404 11 6 0,000 2,587E-03 0,01625351 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 2,587E-03 0,01621118 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 2,587E-03 0,01616907 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 2,587E-03 0,01612719 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 2,587E-03 0,01608551 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 2,587E-03 0,01604406 ! cGMP-mediated signaling GO:0019934 13 6 0,000 2,587E-03 0,01600281 ! activation of MAPKKK activity GO:0000185 12 6 0,000 2,587E-03 0,01596178 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 2,587E-03 0,01592096 ! thymic T cell selection GO:0045061 12 6 0,000 2,587E-03 0,01588034 ! protein lipoylation GO:0009249 10 6 0,000 2,587E-03 0,01583993 ! cysteine metabolic process GO:0006534 10 6 0,000 2,587E-03 0,01579973 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 2,587E-03 0,01575973 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 2,587E-03 0,01571993 ! glutamate catabolic process GO:0006538 10 6 0,000 2,587E-03 0,01568034 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 2,587E-03 0,01564094 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 2,587E-03 0,01560174 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 2,587E-03 0,01556273 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 2,587E-03 0,01552392 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 2,587E-03 0,01548531 ! hyperosmotic response GO:0006972 9 6 0,000 2,587E-03 0,01544688 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 2,587E-03 0,01540865 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 2,587E-03 0,0153706 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 2,587E-03 0,01533274 ! urea metabolic process GO:0019627 7 6 0,000 2,587E-03 0,01529507 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 2,587E-03 0,01525758 ! neutrophil activation GO:0042119 8 6 0,000 2,587E-03 0,01522028 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 2,587E-03 0,01518316 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 2,587E-03 0,01514621 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 2,587E-03 0,01510945 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 2,587E-03 0,01507287 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 2,587E-03 0,01503646 ! nucleoside salvage GO:0043174 9 6 0,000 2,587E-03 0,01500023 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 2,587E-03 0,01496417 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 2,587E-03 0,01492828 ! T cell mediated immunity GO:0002456 16 6 0,000 2,587E-03 0,01489257 ! negative regulation of platelet activation GO:0010544 9 6 0,000 2,587E-03 0,01485703 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 2,587E-03 0,01482165 ! carnitine transport GO:0015879 10 6 0,000 2,587E-03 0,01478645 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 2,587E-03 0,01475141 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 2,587E-03 0,01471653 ! positive regulation of exocytosis GO:0045921 8 6 0,000 2,587E-03 0,01468182 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 2,587E-03 0,01464728 ! 5S class rRNA transcription GO:0042791 11 6 0,000 2,587E-03 0,0146129 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 2,587E-03 0,01457867 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 2,587E-03 0,01454461 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 2,587E-03 0,01451071 ! sodium ion homeostasis GO:0055078 11 6 0,000 2,587E-03 0,01447696 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 2,587E-03 0,01444337 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 2,587E-03 0,01440994 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 2,587E-03 0,01437666 ! neural nucleus development GO:0048857 14 6 0,000 2,587E-03 0,01434353 ! response to UV-C GO:0010225 11 6 0,000 2,587E-03 0,01431056 ! astrocyte development GO:0014002 15 6 0,000 2,587E-03 0,01427774 ! protein targeting to lysosome GO:0006622 10 6 0,000 2,587E-03 0,01424507 ! purine base biosynthetic process GO:0009113 17 6 0,000 2,587E-03 0,01421254 ! interaction with symbiont GO:0051702 13 6 0,000 2,587E-03 0,01418017 ! regulation of dendrite development GO:0050773 16 6 0,000 2,587E-03 0,01414794 ! skeletal muscle contraction GO:0003009 6 6 0,000 2,587E-03 0,01411586 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 2,587E-03 0,01408392 ! response to copper ion GO:0046688 10 6 0,000 2,587E-03 0,01405213 ! response to exogenous dsRNA GO:0043330 10 6 0,000 2,587E-03 0,01402048 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 2,587E-03 0,01398897 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 2,587E-03 0,01395761 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 2,587E-03 0,01392638 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 2,587E-03 0,0138953 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 2,587E-03 0,01386435 ! regulation of dopamine secretion GO:0014059 14 6 0,000 2,587E-03 0,01383354 ! nucleoside catabolic process GO:0009164 7 6 0,000 2,587E-03 0,01380287 ! hair follicle maturation GO:0048820 7 6 0,000 2,587E-03 0,01377233 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 2,587E-03 0,01374193 ! Schwann cell development GO:0014044 15 6 0,000 2,587E-03 0,01371166 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 2,587E-03 0,01368152 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 2,587E-03 0,01365152 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 2,587E-03 0,01362165 ! subpallium development GO:0021544 10 6 0,000 2,587E-03 0,01359191 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 2,587E-03 0,0135623 ! histone ubiquitination GO:0016574 8 6 0,000 2,587E-03 0,01353281 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 2,587E-03 0,01350346 ! maintenance of organ identity GO:0048496 9 6 0,000 2,587E-03 0,01347423 ! G2 phase GO:0051319 16 6 0,000 2,587E-03 0,01344513 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 2,587E-03 0,01341615 ! establishment of planar polarity GO:0001736 7 6 0,000 2,587E-03 0,0133873 ! regulation of mast cell activation GO:0033003 12 6 0,000 2,587E-03 0,01335857 ! membrane to membrane docking GO:0022614 14 6 0,000 2,587E-03 0,01332997 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 2,587E-03 0,01330148 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 2,587E-03 0,01327312 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 2,587E-03 0,01324488 ! receptor internalization GO:0031623 10 6 0,000 2,587E-03 0,01321676 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 2,587E-03 0,01318876 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 2,587E-03 0,01316087 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 2,587E-03 0,01313311 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 2,587E-03 0,01310546 ! protein deubiquitination GO:0016579 14 6 0,000 2,587E-03 0,01307793 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 2,587E-03 0,01305051 ! protein destabilization GO:0031648 9 6 0,000 2,587E-03 0,01302321 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 2,587E-03 0,01299602 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 2,587E-03 0,01296895 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 2,587E-03 0,01294198 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 2,587E-03 0,01291513 ! progesterone metabolic process GO:0042448 10 6 0,000 2,587E-03 0,01288839 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 2,587E-03 0,01286176 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 2,587E-03 0,01283524 ! negative regulation of axon extension GO:0030517 21 6 0,000 2,587E-03 0,01280883 ! removal of superoxide radicals GO:0019430 11 6 0,000 2,587E-03 0,01278253 ! triglyceride catabolic process GO:0019433 10 6 0,000 2,587E-03 0,01275634 ! determination of adult lifespan GO:0008340 15 6 0,000 2,587E-03 0,01273025 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 2,587E-03 0,01270427 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 2,587E-03 0,0126784 ! cerebellar cortex formation GO:0021697 8 6 0,000 2,587E-03 0,01265263 ! catecholamine transport GO:0051937 9 6 0,000 2,587E-03 0,01262696 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 2,587E-03 0,0126014 ! sensory cilium assembly GO:0035058 10 6 0,000 2,587E-03 0,01257595 ! organ or tissue specific immune response GO:0002251 7 6 0,000 2,587E-03 0,01255059 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 2,587E-03 0,01252534 ! maternal placenta development GO:0001893 12 6 0,000 2,587E-03 0,01250019 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 2,587E-03 0,01247514 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 2,587E-03 0,01245019 ! protein amino acid prenylation GO:0018346 16 6 0,000 2,587E-03 0,01242534 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 2,587E-03 0,01240058 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 2,587E-03 0,01237593 ! positive regulation of coagulation GO:0050820 12 6 0,000 2,587E-03 0,01235138 ! tRNA transcription GO:0009304 14 7 0,000 3,018E-03 0,01437854 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 3,018E-03 0,01435012 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 3,018E-03 0,01432182 ! behavioral response to cocaine GO:0048148 14 7 0,000 3,018E-03 0,01429363 ! regulation of helicase activity GO:0051095 15 7 0,000 3,018E-03 0,01426555 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 3,018E-03 0,01423757 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 3,018E-03 0,01420971 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 3,018E-03 0,01418196 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 3,018E-03 0,01415431 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 3,018E-03 0,01412678 ! prostate gland development GO:0030850 13 7 0,000 3,018E-03 0,01409934 ! nucleotide-sugar transport GO:0015780 12 7 0,000 3,018E-03 0,01407202 ! synaptonemal complex assembly GO:0007130 10 7 0,000 3,018E-03 0,0140448 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 3,018E-03 0,01401769 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 3,018E-03 0,01399068 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 3,018E-03 0,01396377 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 3,018E-03 0,01393697 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 3,018E-03 0,01391027 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 3,018E-03 0,01388368 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 3,018E-03 0,01385718 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 3,018E-03 0,01383079 ! SMAD protein complex assembly GO:0007183 12 7 0,000 3,018E-03 0,01380449 ! glycolipid transport GO:0046836 10 7 0,000 3,018E-03 0,0137783 ! protein amino acid sulfation GO:0006477 10 7 0,000 3,018E-03 0,0137522 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 3,018E-03 0,01372621 ! neuron adhesion GO:0007158 12 7 0,000 3,018E-03 0,01370031 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 3,018E-03 0,01367451 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 3,018E-03 0,0136488 ! actin-myosin filament sliding GO:0033275 11 7 0,000 3,018E-03 0,01362319 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 3,018E-03 0,01359768 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 3,018E-03 0,01357227 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 3,018E-03 0,01354695 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 3,018E-03 0,01352172 ! mRNA stabilization GO:0048255 18 7 0,000 3,018E-03 0,01349658 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 3,018E-03 0,01347154 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 3,018E-03 0,0134466 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 3,018E-03 0,01342174 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 3,018E-03 0,01339698 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 3,018E-03 0,01337231 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 3,018E-03 0,01334773 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 3,018E-03 0,01332323 ! lipoprotein transport GO:0042953 14 7 0,000 3,018E-03 0,01329883 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 3,018E-03 0,01327452 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 3,018E-03 0,0132503 ! rhythmic behavior GO:0007622 15 7 0,000 3,018E-03 0,01322616 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 3,018E-03 0,01320211 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 3,018E-03 0,01317815 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 3,018E-03 0,01315428 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 3,018E-03 0,01313049 ! regulation of odontogenesis GO:0042481 13 7 0,000 3,018E-03 0,01310679 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 3,018E-03 0,01308318 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 3,018E-03 0,01305965 ! mechanosensory behavior GO:0007638 14 7 0,000 3,018E-03 0,0130362 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 3,018E-03 0,01301284 ! positive regulation of isotype switching GO:0045830 15 7 0,000 3,018E-03 0,01298956 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 3,018E-03 0,01296636 ! protein-cofactor linkage GO:0018065 13 7 0,000 3,018E-03 0,01294325 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 3,018E-03 0,01292022 ! spinal cord patterning GO:0021511 13 7 0,000 3,018E-03 0,01289727 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 3,018E-03 0,0128744 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 3,018E-03 0,01285162 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 3,018E-03 0,01282891 ! adrenal gland development GO:0030325 17 7 0,000 3,018E-03 0,01280628 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 3,018E-03 0,01278374 ! ovulation GO:0030728 9 7 0,000 3,018E-03 0,01276127 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 3,018E-03 0,01273888 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 3,018E-03 0,01271657 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 3,018E-03 0,01269434 ! microtubule nucleation GO:0007020 20 7 0,000 3,018E-03 0,01267219 ! proline biosynthetic process GO:0006561 10 7 0,000 3,018E-03 0,01265011 ! thyroid hormone generation GO:0006590 13 7 0,000 3,018E-03 0,01262811 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 3,018E-03 0,01260619 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 3,018E-03 0,01258434 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 3,018E-03 0,01256257 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 3,018E-03 0,01254087 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 3,018E-03 0,01251925 ! galactose metabolic process GO:0006012 13 7 0,000 3,018E-03 0,0124977 ! vesicle fusion GO:0006906 17 7 0,000 3,018E-03 0,01247622 ! response to dietary excess GO:0002021 8 7 0,000 3,018E-03 0,01245482 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 3,018E-03 0,0124335 ! intracellular pH reduction GO:0051452 11 7 0,000 3,018E-03 0,01241224 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 3,018E-03 0,01239106 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 3,018E-03 0,01236995 ! organ growth GO:0035265 15 7 0,000 3,018E-03 0,01234892 ! purine salvage GO:0043101 10 7 0,000 3,018E-03 0,01232795 ! nucleoside transport GO:0015858 8 7 0,000 3,018E-03 0,01230706 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 3,018E-03 0,01228623 ! parturition GO:0007567 14 7 0,000 3,018E-03 0,01226548 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 3,018E-03 0,01224479 ! rRNA modification GO:0000154 14 7 0,000 3,018E-03 0,01222418 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 3,018E-03 0,01220363 ! spindle checkpoint GO:0031577 15 7 0,000 3,018E-03 0,01218316 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 3,018E-03 0,01216275 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 3,018E-03 0,01214241 ! macrophage differentiation GO:0030225 11 7 0,000 3,018E-03 0,01212214 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 3,018E-03 0,01210194 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 3,018E-03 0,0120818 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 3,018E-03 0,01206173 ! hyaluronan metabolic process GO:0030212 8 7 0,000 3,018E-03 0,01204173 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 3,018E-03 0,01202179 ! anterograde axon cargo transport GO:0008089 18 7 0,000 3,018E-03 0,01200192 ! fibrinolysis GO:0042730 10 7 0,000 3,018E-03 0,01198212 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 3,018E-03 0,01196238 ! eating behavior GO:0042755 7 7 0,000 3,018E-03 0,0119427 ! B cell lineage commitment GO:0002326 21 7 0,000 3,018E-03 0,01192309 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 3,018E-03 0,01190355 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 3,018E-03 0,01188406 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 3,018E-03 0,01186464 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 3,018E-03 0,01184529 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 3,018E-03 0,011826 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 3,018E-03 0,01180677 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 3,018E-03 0,0117876 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 3,018E-03 0,0117685 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 3,018E-03 0,01174945 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 3,018E-03 0,01173047 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 3,018E-03 0,01171155 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 3,018E-03 0,01169269 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 3,018E-03 0,01167389 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 3,018E-03 0,01165516 ! regulation of meiosis GO:0040020 12 7 0,000 3,018E-03 0,01163648 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 3,018E-03 0,01161786 ! T cell lineage commitment GO:0002360 16 7 0,000 3,018E-03 0,0115993 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 3,018E-03 0,0115808 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 3,018E-03 0,01156236 ! oxygen homeostasis GO:0032364 12 7 0,000 3,018E-03 0,01154398 ! transcription termination GO:0006353 13 7 0,000 3,018E-03 0,01152566 ! response to tumor cell GO:0002347 13 7 0,000 3,018E-03 0,01150739 ! regulation of respiratory burst GO:0060263 11 7 0,000 3,018E-03 0,01148918 ! coenzyme A metabolic process GO:0015936 12 7 0,000 3,018E-03 0,01147103 ! anaphase GO:0051322 17 7 0,000 3,018E-03 0,01145294 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 3,018E-03 0,0114349 ! axonal fasciculation GO:0007413 18 7 0,000 3,018E-03 0,01141692 ! negative regulation of nuclear division GO:0051784 14 7 0,000 3,018E-03 0,011399 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 3,018E-03 0,01138113 ! peptidyl-threonine modification GO:0018210 25 7 0,000 3,018E-03 0,01136332 ! diuresis GO:0030146 12 7 0,000 3,018E-03 0,01134557 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 3,018E-03 0,01132787 ! thiamin metabolic process GO:0006772 7 7 0,000 3,018E-03 0,01131022 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 3,018E-03 0,01129263 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 3,018E-03 0,0112751 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 3,018E-03 0,01125762 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 3,018E-03 0,01124019 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 3,018E-03 0,01122282 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 3,018E-03 0,0112055 ! melanin biosynthetic process GO:0042438 8 7 0,000 3,018E-03 0,01118823 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 3,018E-03 0,01117102 ! dopamine biosynthetic process GO:0042416 18 7 0,000 3,018E-03 0,01115386 ! glycolipid catabolic process GO:0019377 15 7 0,000 3,018E-03 0,01113675 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 3,018E-03 0,0111197 ! lymph node development GO:0048535 10 7 0,000 3,018E-03 0,0111027 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 3,018E-03 0,01108574 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 3,018E-03 0,01106885 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 3,018E-03 0,011052 ! endosome to lysosome transport GO:0008333 11 7 0,000 3,018E-03 0,0110352 ! protein modification by small protein removal GO:0070646 16 7 0,000 3,018E-03 0,01101846 ! adult feeding behavior GO:0008343 9 7 0,000 3,018E-03 0,01100176 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 3,018E-03 0,01098512 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 3,018E-03 0,01096852 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 3,018E-03 0,01095198 ! muscle adaptation GO:0043500 14 7 0,000 3,018E-03 0,01093549 ! embryonic heart tube development GO:0035050 10 7 0,000 3,018E-03 0,01091904 ! retina homeostasis GO:0001895 12 7 0,000 3,018E-03 0,01090265 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 3,018E-03 0,0108863 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 3,018E-03 0,01087 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 3,018E-03 0,01085376 ! protein prenylation GO:0018342 18 7 0,000 3,018E-03 0,01083756 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 3,018E-03 0,0108214 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 3,018E-03 0,0108053 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 3,018E-03 0,01078925 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 3,448E-03 0,01230982 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 3,448E-03 0,01229158 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 3,448E-03 0,0122734 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 3,448E-03 0,01225527 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 3,448E-03 0,0122372 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 3,448E-03 0,01221917 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 3,448E-03 0,0122012 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 3,448E-03 0,01218329 ! neutral lipid catabolic process GO:0046461 13 8 0,000 3,448E-03 0,01216542 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 3,448E-03 0,01214761 ! meiotic prophase I GO:0007128 13 8 0,000 3,448E-03 0,01212985 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 3,448E-03 0,01211214 ! oligopeptide transport GO:0006857 15 8 0,000 3,448E-03 0,01209449 ! UTP metabolic process GO:0046051 8 8 0,000 3,448E-03 0,01207688 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 3,448E-03 0,01205933 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 3,448E-03 0,01204183 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 3,448E-03 0,01202438 ! macrophage chemotaxis GO:0048246 12 8 0,000 3,448E-03 0,01200697 ! succinate metabolic process GO:0006105 14 8 0,000 3,448E-03 0,01198962 ! membrane hyperpolarization GO:0060081 10 8 0,000 3,448E-03 0,01197232 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 3,448E-03 0,01195507 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 3,448E-03 0,01193787 ! T-helper 1 type immune response GO:0042088 12 8 0,000 3,448E-03 0,01192072 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 3,448E-03 0,01190361 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 3,448E-03 0,01188656 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 3,448E-03 0,01186955 ! ganglioside metabolic process GO:0001573 19 8 0,000 3,448E-03 0,0118526 ! reflex GO:0060004 16 8 0,000 3,448E-03 0,01183569 ! negative regulation of endocytosis GO:0045806 11 8 0,000 3,448E-03 0,01181883 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 3,448E-03 0,01180202 ! endothelial cell differentiation GO:0045446 17 8 0,000 3,448E-03 0,01178525 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 3,448E-03 0,01176854 ! glycerolipid catabolic process GO:0046503 13 8 0,000 3,448E-03 0,01175187 ! hemoglobin metabolic process GO:0020027 13 8 0,000 3,448E-03 0,01173525 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 3,448E-03 0,01171867 ! pigment granule organization GO:0048753 16 8 0,000 3,448E-03 0,01170214 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 3,448E-03 0,01168566 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 3,448E-03 0,01166922 ! astrocyte differentiation GO:0048708 18 8 0,000 3,448E-03 0,01165284 ! histidine metabolic process GO:0006547 16 8 0,000 3,448E-03 0,01163649 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 3,448E-03 0,01162019 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 3,448E-03 0,01160394 ! glycine catabolic process GO:0006546 13 8 0,000 3,448E-03 0,01158774 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 3,448E-03 0,01157157 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 3,448E-03 0,01155546 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 3,448E-03 0,01153939 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 3,448E-03 0,01152336 ! regulation of pigmentation during development GO:0048070 24 8 0,000 3,448E-03 0,01150738 ! melanin metabolic process GO:0006582 15 8 0,000 3,448E-03 0,01149144 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 3,448E-03 0,01147554 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 3,448E-03 0,01145969 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 3,448E-03 0,01144389 ! macrophage activation GO:0042116 12 8 0,000 3,448E-03 0,01142813 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 3,448E-03 0,01141241 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 3,448E-03 0,01139673 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 3,448E-03 0,0113811 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 3,448E-03 0,01136551 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 3,448E-03 0,01134996 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 3,448E-03 0,01133445 ! regulation of vascular permeability GO:0043114 12 8 0,000 3,448E-03 0,01131899 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 3,448E-03 0,01130357 ! osteoblast development GO:0002076 16 8 0,000 3,448E-03 0,01128819 ! positive regulation of vasodilation GO:0045909 13 8 0,000 3,448E-03 0,01127285 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 3,448E-03 0,01125756 ! negative regulation of translational initiation GO:0045947 10 8 0,000 3,448E-03 0,0112423 ! Schwann cell differentiation GO:0014037 19 8 0,000 3,448E-03 0,01122709 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 3,448E-03 0,01121192 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 3,448E-03 0,01119679 ! response to UV-B GO:0010224 16 8 0,000 3,448E-03 0,0111817 ! protein targeting to vacuole GO:0006623 12 8 0,000 3,448E-03 0,01116665 ! protein retention in ER lumen GO:0006621 14 8 0,000 3,448E-03 0,01115164 ! intermediate filament organization GO:0045109 12 8 0,000 3,448E-03 0,01113667 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 3,448E-03 0,01112174 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 3,448E-03 0,01110685 ! cellular extravasation GO:0045123 12 8 0,000 3,448E-03 0,011092 ! cardiac muscle cell development GO:0055013 13 8 0,000 3,448E-03 0,01107719 ! regulation of circadian rhythm GO:0042752 16 8 0,000 3,448E-03 0,01106243 ! response to antibiotic GO:0046677 11 8 0,000 3,448E-03 0,01104769 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 3,448E-03 0,011033 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 3,448E-03 0,01101835 ! DNA topological change GO:0006265 12 8 0,000 3,448E-03 0,01100374 ! response to tropane GO:0014073 15 8 0,000 3,448E-03 0,01098916 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 3,448E-03 0,01097463 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 3,448E-03 0,01096013 ! melanosome transport GO:0032402 13 8 0,000 3,448E-03 0,01094567 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 0,000 3,448E-03 0,01093125 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 3,448E-03 0,01091687 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 3,448E-03 0,01090252 ! mast cell activation GO:0045576 14 8 0,000 3,448E-03 0,01088821 ! multicellular organismal aging GO:0010259 18 8 0,000 3,448E-03 0,01087394 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 3,448E-03 0,01085971 ! dendrite morphogenesis GO:0048813 13 8 0,000 3,448E-03 0,01084551 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 3,448E-03 0,01083136 ! nucleosome disassembly GO:0006337 14 8 0,000 3,448E-03 0,01081723 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 3,448E-03 0,01080315 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 3,448E-03 0,0107891 ! leukocyte activation during immune response GO:0002366 13 8 0,000 3,448E-03 0,01077509 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 3,448E-03 0,01076111 ! establishment of chromosome localization GO:0051303 12 8 0,000 3,448E-03 0,01074717 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 3,448E-03 0,01073327 ! intracellular lipid transport GO:0032365 13 8 0,000 3,448E-03 0,0107194 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 3,448E-03 0,01070557 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 3,448E-03 0,01069178 ! regulation of macrophage activation GO:0043030 15 8 0,000 3,448E-03 0,01067802 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 3,448E-03 0,01066429 ! positive regulation of epidermis development GO:0045684 13 8 0,000 3,448E-03 0,0106506 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 3,448E-03 0,01063695 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 3,448E-03 0,01062333 ! hormone catabolic process GO:0042447 17 8 0,000 3,448E-03 0,01060974 ! positive regulation of glucose import GO:0046326 8 8 0,000 3,448E-03 0,01059619 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 3,448E-03 0,01058268 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 3,448E-03 0,0105692 ! ATP catabolic process GO:0006200 11 8 0,000 3,448E-03 0,01055575 ! blastocyst growth GO:0001832 19 8 0,000 3,448E-03 0,01054234 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 3,448E-03 0,01052896 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 3,448E-03 0,01051561 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 3,448E-03 0,0105023 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 3,448E-03 0,01048902 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 3,448E-03 0,01047578 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 3,448E-03 0,01046257 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 3,448E-03 0,01044939 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 3,448E-03 0,01043625 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 3,448E-03 0,01042314 ! amino sugar catabolic process GO:0046348 10 8 0,000 3,448E-03 0,01041006 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 3,448E-03 0,01039702 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 3,448E-03 0,010384 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 3,448E-03 0,01037102 ! behavioral response to nicotine GO:0035095 12 8 0,000 3,448E-03 0,01035808 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 3,448E-03 0,01034516 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 3,448E-03 0,01033228 ! NAD biosynthetic process GO:0009435 13 8 0,000 3,448E-03 0,01031943 ! regulation of developmental growth GO:0048638 15 9 0,000 3,879E-03 0,01159262 ! axon extension GO:0048675 15 9 0,000 3,879E-03 0,01157824 ! autophagic vacuole formation GO:0000045 15 9 0,000 3,879E-03 0,01156389 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 3,879E-03 0,01154958 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 3,879E-03 0,01153531 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 3,879E-03 0,01152106 ! pentose-phosphate shunt GO:0006098 16 9 0,000 3,879E-03 0,01150686 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 3,879E-03 0,01149269 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 3,879E-03 0,01147855 ! cell proliferation in forebrain GO:0021846 15 9 0,000 3,879E-03 0,01146445 ! phosphate transport GO:0006817 19 9 0,000 3,879E-03 0,01145038 ! reproductive behavior GO:0019098 19 9 0,000 3,879E-03 0,01143635 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 3,879E-03 0,01142235 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 3,879E-03 0,01140839 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 3,879E-03 0,01139446 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 3,879E-03 0,01138056 ! GTP metabolic process GO:0046039 9 9 0,000 3,879E-03 0,0113667 ! RNA methylation GO:0001510 15 9 0,000 3,879E-03 0,01135287 ! elastic fiber assembly GO:0048251 15 9 0,000 3,879E-03 0,01133908 ! induction of positive chemotaxis GO:0050930 15 9 0,000 3,879E-03 0,01132532 ! artery development GO:0060840 24 9 0,000 3,879E-03 0,01131159 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 3,879E-03 0,0112979 ! regulation of glycolysis GO:0006110 21 9 0,000 3,879E-03 0,01128423 ! cerebral cortex cell migration GO:0021795 15 9 0,000 3,879E-03 0,01127061 ! keratinocyte proliferation GO:0043616 14 9 0,000 3,879E-03 0,01125701 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 3,879E-03 0,01124345 ! chemosensory behavior GO:0007635 20 9 0,000 3,879E-03 0,01122992 ! microtubule bundle formation GO:0001578 21 9 0,000 3,879E-03 0,01121642 ! middle ear morphogenesis GO:0042474 14 9 0,000 3,879E-03 0,01120296 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 3,879E-03 0,01118952 ! leukocyte degranulation GO:0043299 16 9 0,000 3,879E-03 0,01117612 ! bile acid and bile salt transport GO:0015721 13 9 0,000 3,879E-03 0,01116275 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 3,879E-03 0,01114942 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 3,879E-03 0,01113611 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 3,879E-03 0,01112284 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 3,879E-03 0,0111096 ! protein targeting to ER GO:0045047 22 9 0,000 3,879E-03 0,01109639 ! ceramide biosynthetic process GO:0046513 19 9 0,000 3,879E-03 0,01108321 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 3,879E-03 0,01107006 ! T cell selection GO:0045058 23 9 0,000 3,879E-03 0,01105695 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 3,879E-03 0,01104386 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 3,879E-03 0,01103081 ! phosphagen metabolic process GO:0006599 12 9 0,000 3,879E-03 0,01101778 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 3,879E-03 0,01100479 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 3,879E-03 0,01099183 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 3,879E-03 0,0109789 ! regulation of type I interferon production GO:0032479 12 9 0,000 3,879E-03 0,010966 ! mannose metabolic process GO:0006013 13 9 0,000 3,879E-03 0,01095312 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 3,879E-03 0,01094028 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 3,879E-03 0,01092747 ! Rac protein signal transduction GO:0016601 17 9 0,000 3,879E-03 0,01091469 ! receptor clustering GO:0043113 18 9 0,000 3,879E-03 0,01090194 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 3,879E-03 0,01088922 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 3,879E-03 0,01087653 ! ruffle organization GO:0031529 15 9 0,000 3,879E-03 0,01086387 ! retinol metabolic process GO:0042572 18 9 0,000 3,879E-03 0,01085123 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 3,879E-03 0,01083863 ! behavioral fear response GO:0001662 22 9 0,000 3,879E-03 0,01082606 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 3,879E-03 0,01081351 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 3,879E-03 0,010801 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 3,879E-03 0,01078851 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 3,879E-03 0,01077605 ! protein heterooligomerization GO:0051291 16 9 0,000 3,879E-03 0,01076362 ! oligodendrocyte development GO:0014003 10 9 0,000 3,879E-03 0,01075122 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 3,879E-03 0,01073885 ! segment specification GO:0007379 13 9 0,000 3,879E-03 0,01072651 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 3,879E-03 0,01071419 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 3,879E-03 0,01070191 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 3,879E-03 0,01068965 ! response to amine stimulus GO:0014075 13 9 0,000 3,879E-03 0,01067742 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 3,879E-03 0,01066521 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 3,879E-03 0,01065304 ! erythrocyte development GO:0048821 15 9 0,000 3,879E-03 0,01064089 ! gas homeostasis GO:0033483 16 9 0,000 3,879E-03 0,01062877 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 3,879E-03 0,01061668 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 3,879E-03 0,01060462 ! renal water homeostasis GO:0003091 14 9 0,000 3,879E-03 0,01059258 ! postreplication repair GO:0006301 22 9 0,000 3,879E-03 0,01058057 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 3,879E-03 0,01056859 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 3,879E-03 0,01055663 ! icosanoid secretion GO:0032309 15 9 0,000 3,879E-03 0,0105447 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 3,879E-03 0,0105328 ! cerebellum morphogenesis GO:0021587 14 9 0,000 3,879E-03 0,01052093 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 3,879E-03 0,01050908 ! regulation of cell division GO:0051302 15 9 0,000 3,879E-03 0,01049726 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 3,879E-03 0,01048546 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 3,879E-03 0,01047369 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 3,879E-03 0,01046195 ! sterol catabolic process GO:0016127 11 9 0,000 3,879E-03 0,01045024 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 3,879E-03 0,01043855 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 3,879E-03 0,01042689 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 3,879E-03 0,01041525 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 3,879E-03 0,01040364 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 3,879E-03 0,01039205 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 3,879E-03 0,01038049 ! musculoskeletal movement GO:0050881 14 9 0,000 3,879E-03 0,01036896 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 3,879E-03 0,01035745 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 3,879E-03 0,01034597 ! regulation of synaptogenesis GO:0051963 15 9 0,000 3,879E-03 0,01033451 ! purine base metabolic process GO:0006144 21 9 0,000 3,879E-03 0,01032308 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 3,879E-03 0,01031167 ! pigment granule transport GO:0051904 17 9 0,000 3,879E-03 0,01030029 ! regulation of fibrinolysis GO:0051917 16 9 0,000 3,879E-03 0,01028893 ! regulation of telomere maintenance GO:0032204 14 9 0,000 3,879E-03 0,0102776 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 3,879E-03 0,01026629 ! regulation of muscle adaptation GO:0043502 14 9 0,000 3,879E-03 0,01025501 ! regulation of amino acid transport GO:0051955 11 9 0,000 3,879E-03 0,01024376 ! mitochondrion localization GO:0051646 15 9 0,000 3,879E-03 0,01023252 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 4,309E-03 0,01135476 ! negative regulation of blood pressure GO:0045776 26 10 0,000 4,309E-03 0,01134233 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 4,309E-03 0,01132994 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 4,309E-03 0,01131757 ! regulation of phosphatase activity GO:0010921 28 10 0,000 4,309E-03 0,01130523 ! synapsis GO:0007129 13 10 0,000 4,309E-03 0,01129291 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 4,309E-03 0,01128062 ! N-glycan processing GO:0006491 20 10 0,000 4,309E-03 0,01126836 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 4,309E-03 0,01125613 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 4,309E-03 0,01124392 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 4,309E-03 0,01123174 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 4,309E-03 0,01121958 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 4,309E-03 0,01120745 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 4,309E-03 0,01119535 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 4,309E-03 0,01118327 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 4,309E-03 0,01117122 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 4,309E-03 0,0111592 ! androgen metabolic process GO:0008209 17 10 0,000 4,309E-03 0,0111472 ! phospholipid efflux GO:0033700 16 10 0,000 4,309E-03 0,01113522 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 4,309E-03 0,01112328 ! positive regulation of heart contraction GO:0045823 16 10 0,000 4,309E-03 0,01111135 ! lung alveolus development GO:0048286 26 10 0,000 4,309E-03 0,01109946 ! pathogenesis GO:0009405 13 10 0,000 4,309E-03 0,01108759 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 4,309E-03 0,01107574 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 4,309E-03 0,01106392 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 4,309E-03 0,01105212 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 4,309E-03 0,01104035 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 4,309E-03 0,01102861 ! endoderm development GO:0007492 16 10 0,000 4,309E-03 0,01101689 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 4,309E-03 0,01100519 ! arginine catabolic process GO:0006527 13 10 0,000 4,309E-03 0,01099352 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 4,309E-03 0,01098188 ! proline metabolic process GO:0006560 13 10 0,000 4,309E-03 0,01097026 ! glucan biosynthetic process GO:0009250 14 10 0,000 4,309E-03 0,01095866 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 4,309E-03 0,01094709 ! polyamine biosynthetic process GO:0006596 12 10 0,000 4,309E-03 0,01093554 ! V(D)J recombination GO:0033151 28 10 0,000 4,309E-03 0,01092402 ! reverse cholesterol transport GO:0043691 16 10 0,000 4,309E-03 0,01091252 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 4,309E-03 0,01090104 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 4,309E-03 0,01088959 ! B cell proliferation GO:0042100 18 10 0,000 4,309E-03 0,01087817 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 4,309E-03 0,01086676 ! regulation of sodium ion transport GO:0002028 21 10 0,000 4,309E-03 0,01085539 ! multicellular organism growth GO:0035264 18 10 0,000 4,309E-03 0,01084403 ! phagocytosis, engulfment GO:0006911 28 10 0,000 4,309E-03 0,0108327 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 4,309E-03 0,01082139 ! epithelial cell development GO:0002064 20 10 0,000 4,309E-03 0,01081011 ! lens development in camera-type eye GO:0002088 16 10 0,000 4,309E-03 0,01079885 ! retinoic acid metabolic process GO:0042573 14 10 0,000 4,309E-03 0,01078761 ! macroautophagy GO:0016236 17 10 0,000 4,309E-03 0,0107764 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 4,309E-03 0,01076521 ! positive regulation of translational initiation GO:0045948 11 10 0,000 4,309E-03 0,01075404 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 4,309E-03 0,01074289 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 4,309E-03 0,01073177 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 4,309E-03 0,01072068 ! copper ion homeostasis GO:0055070 13 10 0,000 4,309E-03 0,0107096 ! regulation of bone resorption GO:0045124 25 10 0,000 4,309E-03 0,01069855 ! regulation of gliogenesis GO:0014013 23 10 0,000 4,309E-03 0,01068752 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 4,309E-03 0,01067651 ! alpha-beta T cell activation GO:0046631 23 10 0,000 4,309E-03 0,01066553 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 4,309E-03 0,01065457 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 4,309E-03 0,01064363 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 4,309E-03 0,01063271 ! blastoderm segmentation GO:0007350 18 10 0,000 4,309E-03 0,01062182 ! response to dsRNA GO:0043331 20 10 0,000 4,309E-03 0,01061094 ! DNA ligation GO:0006266 19 10 0,000 4,309E-03 0,01060009 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 4,309E-03 0,01058927 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 4,309E-03 0,01057846 ! melanosome localization GO:0032400 16 10 0,000 4,309E-03 0,01056768 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 4,309E-03 0,01055692 ! regulation of B cell differentiation GO:0045577 19 10 0,000 4,309E-03 0,01054618 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 4,309E-03 0,01053546 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 4,309E-03 0,01052476 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 4,309E-03 0,01051409 ! mRNA cleavage GO:0006379 17 10 0,000 4,309E-03 0,01050344 ! protein sumoylation GO:0016925 15 10 0,000 4,309E-03 0,01049281 ! hindbrain morphogenesis GO:0021575 19 10 0,000 4,309E-03 0,0104822 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 4,309E-03 0,01047161 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 4,309E-03 0,01046104 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 4,309E-03 0,0104505 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 4,309E-03 0,01043997 ! salivary gland development GO:0007431 27 10 0,000 4,309E-03 0,01042947 ! prophase GO:0051324 15 10 0,000 4,309E-03 0,01041899 ! negative regulation of neurological system process GO:0031645 19 10 0,000 4,309E-03 0,01040853 ! apical protein localization GO:0045176 15 10 0,000 4,309E-03 0,01039809 ! ubiquinone metabolic process GO:0006743 15 10 0,000 4,309E-03 0,01038767 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 4,309E-03 0,01037727 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 4,309E-03 0,01036689 ! midbrain development GO:0030901 13 10 0,000 4,309E-03 0,01035654 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 4,309E-03 0,0103462 ! methionine biosynthetic process GO:0009086 19 10 0,000 4,309E-03 0,01033589 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 4,309E-03 0,01032559 ! quaternary ammonium group transport GO:0015697 21 10 0,000 4,309E-03 0,01031532 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 4,309E-03 0,01030506 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 4,309E-03 0,01029483 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 4,309E-03 0,01028462 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 4,309E-03 0,01027442 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 4,309E-03 0,01026425 ! oocyte development GO:0048599 17 10 0,000 4,309E-03 0,0102541 ! establishment of pigment granule localization GO:0051905 18 10 0,000 4,309E-03 0,01024397 ! blastocyst formation GO:0001825 17 10 0,000 4,309E-03 0,01023385 ! cerebellar cortex development GO:0021695 15 10 0,000 4,309E-03 0,01022376 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 4,309E-03 0,01021369 ! activation of innate immune response GO:0002218 12 10 0,000 4,309E-03 0,01020363 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 4,309E-03 0,0101936 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 4,309E-03 0,01018359 ! response to nicotine GO:0035094 20 10 0,000 4,309E-03 0,01017359 ! establishment of cell polarity GO:0030010 16 10 0,000 4,309E-03 0,01016362 ! negative regulation of immune effector process GO:0002698 20 10 0,000 4,309E-03 0,01015367 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 4,309E-03 0,01014373 ! localization within membrane GO:0051668 20 10 0,000 4,309E-03 0,01013382 ! negative regulation of muscle development GO:0048635 20 11 0,000 4,739E-03 0,01113409 ! respiratory burst GO:0045730 17 11 0,000 4,739E-03 0,01112323 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 4,739E-03 0,01111239 ! neuron fate specification GO:0048665 17 11 0,000 4,739E-03 0,01110157 ! telencephalon cell migration GO:0022029 20 11 0,000 4,739E-03 0,01109077 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 4,739E-03 0,01107999 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 4,739E-03 0,01106923 ! thyroid gland development GO:0030878 26 11 0,000 4,739E-03 0,0110585 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 4,739E-03 0,01104778 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 4,739E-03 0,01103709 ! Golgi vesicle budding GO:0048194 22 11 0,000 4,739E-03 0,01102641 ! response to pain GO:0048265 24 11 0,000 4,739E-03 0,01101576 ! detection of mechanical stimulus GO:0050982 22 11 0,000 4,739E-03 0,01100513 ! T cell proliferation GO:0042098 26 11 0,000 4,739E-03 0,01099451 ! blood vessel remodeling GO:0001974 29 11 0,000 4,739E-03 0,01098392 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 4,739E-03 0,01097335 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 4,739E-03 0,0109628 ! bone resorption GO:0045453 16 11 0,000 4,739E-03 0,01095227 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 4,739E-03 0,01094176 ! ventral spinal cord development GO:0021517 21 11 0,000 4,739E-03 0,01093127 ! negative regulation of proteolysis GO:0045861 25 11 0,000 4,739E-03 0,0109208 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 4,739E-03 0,01091035 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 4,739E-03 0,01089991 ! melanocyte differentiation GO:0030318 21 11 0,000 4,739E-03 0,0108895 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 4,739E-03 0,01087911 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 4,739E-03 0,01086874 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 4,739E-03 0,01085839 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 4,739E-03 0,01084806 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 4,739E-03 0,01083775 ! lipid digestion GO:0044241 18 11 0,000 4,739E-03 0,01082746 ! substrate-bound cell migration GO:0006929 13 11 0,000 4,739E-03 0,01081718 ! UV protection GO:0009650 19 11 0,000 4,739E-03 0,01080693 ! adult heart development GO:0007512 14 11 0,000 4,739E-03 0,0107967 ! chondrocyte differentiation GO:0002062 24 11 0,000 4,739E-03 0,01078648 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 4,739E-03 0,01077629 ! temperature homeostasis GO:0001659 17 11 0,000 4,739E-03 0,01076611 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 4,739E-03 0,01075595 ! negative regulation of ossification GO:0030279 26 11 0,000 4,739E-03 0,01074582 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 4,739E-03 0,0107357 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 4,739E-03 0,0107256 ! regulation of organ growth GO:0046620 13 11 0,000 4,739E-03 0,01071552 ! pigment granule localization GO:0051875 20 11 0,000 4,739E-03 0,01070546 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 4,739E-03 0,01069541 ! vasoconstriction GO:0042310 18 11 0,000 4,739E-03 0,01068539 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 4,739E-03 0,01067538 ! embryonic axis specification GO:0000578 18 11 0,000 4,739E-03 0,0106654 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 4,739E-03 0,01065543 ! snRNA metabolic process GO:0016073 24 11 0,000 4,739E-03 0,01064548 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 4,739E-03 0,01063555 ! nitric oxide metabolic process GO:0046209 15 11 0,000 4,739E-03 0,01062564 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 4,739E-03 0,01061575 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 4,739E-03 0,01060587 ! zymogen activation GO:0031638 15 11 0,000 4,739E-03 0,01059601 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 4,739E-03 0,01058618 ! neuroblast proliferation GO:0007405 24 11 0,000 4,739E-03 0,01057636 ! nucleosome positioning GO:0016584 15 11 0,000 4,739E-03 0,01056655 ! regulation of isotype switching GO:0045191 22 11 0,000 4,739E-03 0,01055677 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 4,739E-03 0,010547 ! glutathione biosynthetic process GO:0006750 13 11 0,000 4,739E-03 0,01053726 ! regulation of leukocyte migration GO:0002685 26 11 0,000 4,739E-03 0,01052753 ! acid secretion GO:0046717 18 11 0,000 4,739E-03 0,01051781 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 4,739E-03 0,01050812 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 4,739E-03 0,01049844 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 4,739E-03 0,01048879 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 4,739E-03 0,01047915 ! oocyte differentiation GO:0009994 18 11 0,000 4,739E-03 0,01046952 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 4,739E-03 0,01045992 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 4,739E-03 0,01045033 ! cholesterol efflux GO:0033344 19 11 0,000 4,739E-03 0,01044076 ! anterior/posterior axis specification GO:0009948 18 11 0,000 4,739E-03 0,01043121 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 4,739E-03 0,01042167 ! negative regulation of glucose import GO:0046325 17 11 0,000 4,739E-03 0,01041216 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 4,739E-03 0,01040266 ! embryonic gut development GO:0048566 15 11 0,000 4,739E-03 0,01039317 ! regulation of organic acid transport GO:0032890 18 11 0,000 4,739E-03 0,01038371 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 4,739E-03 0,01037426 ! cardiac cell differentiation GO:0035051 31 11 0,000 4,739E-03 0,01036483 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 4,739E-03 0,01035541 ! defense response to fungus GO:0050832 13 11 0,000 4,739E-03 0,01034602 ! developmental induction GO:0031128 19 11 0,000 4,739E-03 0,01033664 GO:0045168|cell-cell signaling involved in cell fate specification, ! prepulse inhibition GO:0060134 18 11 0,000 4,739E-03 0,01032727 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 4,739E-03 0,01031793 ! sequestering of metal ion GO:0051238 14 11 0,000 4,739E-03 0,0103086 ! lamellipodium assembly GO:0030032 20 11 0,000 4,739E-03 0,01029929 ! regulation of embryonic development GO:0045995 27 11 0,000 4,739E-03 0,01028999 ! nucleus localization GO:0051647 19 11 0,000 4,739E-03 0,01028071 ! regulation of synapse organization GO:0050807 17 11 0,000 4,739E-03 0,01027145 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 5,168E-03 0,0111929 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 5,168E-03 0,01118284 ! positive regulation of blood pressure GO:0045777 17 12 0,000 5,168E-03 0,01117279 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 5,168E-03 0,01116276 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 5,168E-03 0,01115275 ! virus-host interaction GO:0019048 29 12 0,000 5,168E-03 0,01114276 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 5,168E-03 0,01113278 ! cartilage condensation GO:0001502 20 12 0,000 5,168E-03 0,01112282 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 5,168E-03 0,01111288 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 5,168E-03 0,01110296 ! protein complex disassembly GO:0043241 27 12 0,000 5,168E-03 0,01109306 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 5,168E-03 0,01108317 ! regulation of cell projection assembly GO:0060491 30 12 0,000 5,168E-03 0,0110733 ! hippocampus development GO:0021766 26 12 0,000 5,168E-03 0,01106345 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 5,168E-03 0,01105362 ! cytokine biosynthetic process GO:0042089 21 12 0,000 5,168E-03 0,0110438 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 5,168E-03 0,011034 ! positive regulation of cell growth GO:0030307 22 12 0,000 5,168E-03 0,01102422 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 5,168E-03 0,01101445 ! regulation of exit from mitosis GO:0007096 17 12 0,000 5,168E-03 0,01100471 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 5,168E-03 0,01099498 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 5,168E-03 0,01098526 ! drug transport GO:0015893 16 12 0,000 5,168E-03 0,01097557 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 5,168E-03 0,01096589 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 5,168E-03 0,01095623 ! tyrosine metabolic process GO:0006570 16 12 0,000 5,168E-03 0,01094658 ! polyamine metabolic process GO:0006595 17 12 0,000 5,168E-03 0,01093695 ! focal adhesion formation GO:0048041 35 12 0,000 5,168E-03 0,01092734 ! mitotic spindle organization GO:0007052 21 12 0,000 5,168E-03 0,01091775 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 5,168E-03 0,01090817 ! forebrain cell migration GO:0021885 21 12 0,000 5,168E-03 0,01089861 ! asymmetric protein localization GO:0008105 20 12 0,000 5,168E-03 0,01088907 ! membrane protein proteolysis GO:0033619 25 12 0,000 5,168E-03 0,01087954 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 5,168E-03 0,01087003 ! entry into host cell GO:0030260 32 12 0,000 5,168E-03 0,01086054 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 5,168E-03 0,01085106 ! monoamine transport GO:0015844 18 12 0,000 5,168E-03 0,0108416 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 5,168E-03 0,01083216 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 5,168E-03 0,01082273 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 5,168E-03 0,01081332 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 5,168E-03 0,01080392 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 5,168E-03 0,01079455 ! protein targeting to peroxisome GO:0006625 23 12 0,000 5,168E-03 0,01078518 ! protein homotetramerization GO:0051289 21 12 0,000 5,168E-03 0,01077584 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 5,168E-03 0,01076651 ! regulation of phagocytosis GO:0050764 16 12 0,000 5,168E-03 0,01075719 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 5,168E-03 0,0107479 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 5,168E-03 0,01073862 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 5,168E-03 0,01072935 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 5,168E-03 0,0107201 ! cranial nerve development GO:0021545 20 12 0,000 5,168E-03 0,01071087 ! fucose catabolic process GO:0019317 22 12 0,000 5,168E-03 0,01070165 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 5,168E-03 0,01069245 ! histone acetylation GO:0016573 26 12 0,000 5,168E-03 0,01068326 ! histone methylation GO:0016571 26 12 0,000 5,168E-03 0,01067409 ! mRNA polyadenylation GO:0006378 23 12 0,000 5,168E-03 0,01066494 ! autonomic nervous system development GO:0048483 24 12 0,000 5,168E-03 0,0106558 ! gland morphogenesis GO:0022612 29 12 0,000 5,168E-03 0,01064668 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 5,168E-03 0,01063757 ! peptidyl-lysine modification GO:0018205 21 12 0,000 5,168E-03 0,01062848 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 5,168E-03 0,0106194 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 5,168E-03 0,01061034 ! spleen development GO:0048536 22 12 0,000 5,168E-03 0,01060129 ! digestive tract morphogenesis GO:0048546 26 12 0,000 5,168E-03 0,01059226 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 5,168E-03 0,01058325 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 5,168E-03 0,01057425 ! regulation of RNA splicing GO:0043484 20 12 0,000 5,168E-03 0,01056527 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 5,168E-03 0,0105563 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 5,168E-03 0,01054734 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 5,168E-03 0,0105384 ! response to cold GO:0009409 17 12 0,000 5,168E-03 0,01052948 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 5,168E-03 0,01052057 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 5,168E-03 0,01051168 ! cGMP metabolic process GO:0046068 18 13 0,000 5,598E-03 0,01137577 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 5,598E-03 0,01136617 ! regulation of chemokine production GO:0032642 18 13 0,000 5,598E-03 0,01135659 ! peroxisomal transport GO:0043574 24 13 0,000 5,598E-03 0,01134702 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 5,598E-03 0,01133747 ! lipid localization GO:0010876 28 13 0,000 5,598E-03 0,01132793 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 5,598E-03 0,01131841 ! organelle fusion GO:0048284 32 13 0,000 5,598E-03 0,01130891 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 5,598E-03 0,01129942 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 5,598E-03 0,01128995 ! pseudouridine synthesis GO:0001522 17 13 0,000 5,598E-03 0,01128049 ! endocrine pancreas development GO:0031018 22 13 0,000 5,598E-03 0,01127106 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 5,598E-03 0,01126163 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 5,598E-03 0,01125222 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 5,598E-03 0,01124283 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 5,598E-03 0,01123345 ! methionine metabolic process GO:0006555 27 13 0,000 5,598E-03 0,01122409 ! plasma membrane organization GO:0007009 24 13 0,000 5,598E-03 0,01121475 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 5,598E-03 0,01120542 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 5,598E-03 0,0111961 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 5,598E-03 0,0111868 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 5,598E-03 0,01117752 ! cell-cell junction assembly GO:0007043 27 13 0,000 5,598E-03 0,01116825 ! response to X-ray GO:0010165 25 13 0,000 5,598E-03 0,011159 ! cytokine metabolic process GO:0042107 22 13 0,000 5,598E-03 0,01114976 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 5,598E-03 0,01114054 ! exocrine system development GO:0035272 32 13 0,000 5,598E-03 0,01113133 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 5,598E-03 0,01112214 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 5,598E-03 0,01111296 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 5,598E-03 0,0111038 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 5,598E-03 0,01109465 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 5,598E-03 0,01108552 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 5,598E-03 0,01107641 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 5,598E-03 0,01106731 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 5,598E-03 0,01105822 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 5,598E-03 0,01104915 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 5,598E-03 0,01104009 ! regulation of cellular pH GO:0030641 22 13 0,000 5,598E-03 0,01103105 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 5,598E-03 0,01102202 ! ribosome assembly GO:0042255 17 13 0,000 5,598E-03 0,01101301 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 5,598E-03 0,01100401 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 5,598E-03 0,01099503 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 5,598E-03 0,01098606 ! chromatin silencing GO:0006342 26 13 0,000 5,598E-03 0,01097711 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 5,598E-03 0,01096817 ! regulation of epidermis development GO:0045682 19 13 0,000 5,598E-03 0,01095924 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 5,598E-03 0,01095033 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 5,598E-03 0,01094144 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 5,598E-03 0,01093256 ! regulation of mRNA stability GO:0043488 31 13 0,000 5,598E-03 0,01092369 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 5,598E-03 0,01091484 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 5,598E-03 0,010906 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 5,598E-03 0,01089718 ! mRNA 3'-end processing GO:0031124 24 13 0,000 5,598E-03 0,01088837 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 5,598E-03 0,01087957 ! embryonic placenta development GO:0001892 23 13 0,000 5,598E-03 0,01087079 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 5,598E-03 0,01086202 ! insulin secretion GO:0030073 23 13 0,000 5,598E-03 0,01085327 ! actin filament polymerization GO:0030041 24 13 0,000 5,598E-03 0,01084453 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 5,598E-03 0,01083581 ! acrosome reaction GO:0007340 18 13 0,000 5,598E-03 0,0108271 ! rRNA transcription GO:0009303 25 14 0,000 6,027E-03 0,01164827 ! lactation GO:0007595 26 14 0,000 6,027E-03 0,01163892 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 6,027E-03 0,01162959 ! reproductive cellular process GO:0048610 20 14 0,000 6,027E-03 0,01162027 ! tRNA modification GO:0006400 20 14 0,000 6,027E-03 0,01161096 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 6,027E-03 0,01160167 ! regulation of S phase GO:0033261 23 14 0,000 6,027E-03 0,0115924 ! water transport GO:0006833 21 14 0,000 6,027E-03 0,01158314 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 6,027E-03 0,0115739 ! non-recombinational repair GO:0000726 25 14 0,000 6,027E-03 0,01156467 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 6,027E-03 0,01155545 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 6,027E-03 0,01154625 ! retina development in camera-type eye GO:0060041 27 14 0,000 6,027E-03 0,01153707 ! hair follicle morphogenesis GO:0031069 26 14 0,000 6,027E-03 0,0115279 ! RNA polyadenylation GO:0043631 30 14 0,000 6,027E-03 0,01151874 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 6,027E-03 0,0115096 ! palate development GO:0060021 31 14 0,000 6,027E-03 0,01150047 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 6,027E-03 0,01149136 ! regulated secretory pathway GO:0045055 23 14 0,000 6,027E-03 0,01148226 ! regulation of mRNA processing GO:0050684 24 14 0,000 6,027E-03 0,01147317 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 6,027E-03 0,0114641 ! arginine metabolic process GO:0006525 17 14 0,000 6,027E-03 0,01145505 ! regulation of heart rate GO:0002027 24 14 0,000 6,027E-03 0,01144601 ! organic alcohol transport GO:0015850 29 14 0,000 6,027E-03 0,01143698 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 6,027E-03 0,01142797 ! negative regulation of caspase activity GO:0043154 22 14 0,000 6,027E-03 0,01141897 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 6,027E-03 0,01140999 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 6,027E-03 0,01140102 ! neutral amino acid transport GO:0015804 26 14 0,000 6,027E-03 0,01139206 ! L-amino acid transport GO:0015807 30 14 0,000 6,027E-03 0,01138312 ! bone mineralization GO:0030282 17 14 0,000 6,027E-03 0,01137419 ! stem cell development GO:0048864 43 14 0,000 6,027E-03 0,01136528 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 6,027E-03 0,01135638 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 6,027E-03 0,01134749 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 6,027E-03 0,01133862 ! cerebellum development GO:0021549 21 14 0,000 6,027E-03 0,01132976 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 6,027E-03 0,01132092 ! negative regulation of protein secretion GO:0050709 28 14 0,000 6,027E-03 0,01131208 ! response to gamma radiation GO:0010332 28 14 0,000 6,027E-03 0,01130327 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 6,027E-03 0,01129446 ! cofactor transport GO:0051181 26 14 0,000 6,027E-03 0,01128568 ! NADP metabolic process GO:0006739 24 14 0,000 6,027E-03 0,0112769 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 6,027E-03 0,01126814 ! protein-chromophore linkage GO:0018298 19 14 0,000 6,027E-03 0,01125939 ! intestinal absorption GO:0050892 25 14 0,000 6,027E-03 0,01125065 ! cAMP biosynthetic process GO:0006171 23 14 0,000 6,027E-03 0,01124193 ! oxygen transport GO:0015671 21 14 0,000 6,027E-03 0,01123322 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 6,027E-03 0,01122453 ! male genitalia development GO:0030539 24 14 0,000 6,027E-03 0,01121585 ! regulation of RNA stability GO:0043487 32 14 0,000 6,027E-03 0,01120718 ! regulation of axon extension GO:0030516 37 14 0,000 6,027E-03 0,01119853 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 6,027E-03 0,01118989 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 6,457E-03 0,01197753 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 6,457E-03 0,01196831 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 6,457E-03 0,01195909 ! superoxide anion generation GO:0042554 20 15 0,000 6,457E-03 0,01194989 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 6,457E-03 0,01194071 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 6,457E-03 0,01193154 ! phospholipid catabolic process GO:0009395 22 15 0,000 6,457E-03 0,01192238 ! copper ion transport GO:0006825 20 15 0,000 6,457E-03 0,01191324 ! heterophilic cell adhesion GO:0007157 39 15 0,000 6,457E-03 0,01190411 ! cardiac muscle contraction GO:0060048 26 15 0,000 6,457E-03 0,01189499 ! sulfate transport GO:0008272 23 15 0,000 6,457E-03 0,01188589 ! response to cAMP GO:0051591 22 15 0,000 6,457E-03 0,01187681 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 6,457E-03 0,01186773 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 6,457E-03 0,01185867 ! ciliary or flagellar motility GO:0001539 20 15 0,000 6,457E-03 0,01184963 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 6,457E-03 0,0118406 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 6,457E-03 0,01183158 ! response to hexose stimulus GO:0009746 22 15 0,000 6,457E-03 0,01182257 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 6,457E-03 0,01181358 ! glycoprotein catabolic process GO:0006516 26 15 0,000 6,457E-03 0,01180461 ! pituitary gland development GO:0021983 29 15 0,000 6,457E-03 0,01179564 ! vesicle coating GO:0006901 33 15 0,000 6,457E-03 0,01178669 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 6,457E-03 0,01177776 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 6,457E-03 0,01176884 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 6,457E-03 0,01175993 ! regulation of exocytosis GO:0017157 22 15 0,000 6,457E-03 0,01175103 ! G1/S transition checkpoint GO:0031575 40 15 0,000 6,457E-03 0,01174215 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 6,457E-03 0,01173328 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 6,457E-03 0,01172442 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 6,457E-03 0,01171558 ! regulation of vasodilation GO:0042312 26 15 0,000 6,457E-03 0,01170675 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 6,457E-03 0,01169794 ! histone deacetylation GO:0016575 20 15 0,000 6,457E-03 0,01168914 ! mRNA splice site selection GO:0006376 38 15 0,000 6,457E-03 0,01168035 ! tissue regeneration GO:0042246 26 15 0,000 6,457E-03 0,01167157 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 6,457E-03 0,01166281 ! water homeostasis GO:0030104 27 15 0,000 6,457E-03 0,01165406 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 6,457E-03 0,01164532 ! muscle maintenance GO:0046716 26 15 0,000 6,457E-03 0,0116366 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 6,457E-03 0,01162789 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 6,457E-03 0,01161919 ! regulation of ATPase activity GO:0043462 21 15 0,000 6,457E-03 0,01161051 ! dopamine metabolic process GO:0042417 35 15 0,000 6,457E-03 0,01160184 ! heme biosynthetic process GO:0006783 29 15 0,000 6,457E-03 0,01159318 ! cell killing GO:0001906 29 15 0,000 6,457E-03 0,01158454 ! detection of bacterium GO:0016045 18 15 0,000 6,457E-03 0,0115759 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 6,457E-03 0,01156728 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 6,457E-03 0,01155868 ! L-fucose metabolic process GO:0042354 30 15 0,000 6,457E-03 0,01155008 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 6,457E-03 0,0115415 ! peptide hormone processing GO:0016486 23 15 0,000 6,457E-03 0,01153293 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 6,886E-03 0,01229022 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 6,886E-03 0,01228111 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 6,886E-03 0,01227202 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 6,886E-03 0,01226293 ! dicarboxylic acid transport GO:0006835 38 16 0,000 6,886E-03 0,01225386 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 6,886E-03 0,0122448 ! bone remodeling GO:0046849 27 16 0,000 6,886E-03 0,01223576 ! filopodium assembly GO:0046847 32 16 0,000 6,886E-03 0,01222673 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 6,886E-03 0,01221771 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 6,886E-03 0,01220871 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 6,886E-03 0,01219972 ! positive regulation of ion transport GO:0043270 21 16 0,000 6,886E-03 0,01219074 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 6,886E-03 0,01218178 ! startle response GO:0001964 28 16 0,000 6,886E-03 0,01217283 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 6,886E-03 0,01216389 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 6,886E-03 0,01215497 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 6,886E-03 0,01214606 ! activation of MAPKK activity GO:0000186 35 16 0,000 6,886E-03 0,01213716 ! regulation of defense response to virus GO:0050688 27 16 0,000 6,886E-03 0,01212827 ! protein polyubiquitination GO:0000209 34 16 0,000 6,886E-03 0,0121194 ! glutamate metabolic process GO:0006536 22 16 0,000 6,886E-03 0,01211054 ! complement activation, alternative pathway GO:0006957 18 16 0,000 6,886E-03 0,0121017 ! response to osmotic stress GO:0006970 25 16 0,000 6,886E-03 0,01209286 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 6,886E-03 0,01208404 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 6,886E-03 0,01207523 ! fructose metabolic process GO:0006000 25 16 0,000 6,886E-03 0,01206644 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 6,886E-03 0,01205766 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 6,886E-03 0,01204889 ! intermediate filament-based process GO:0045103 32 16 0,000 6,886E-03 0,01204013 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 6,886E-03 0,01203139 ! negative regulation of immune response GO:0050777 35 16 0,000 6,886E-03 0,01202266 ! axon cargo transport GO:0008088 43 16 0,000 6,886E-03 0,01201394 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 6,886E-03 0,01200523 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 6,886E-03 0,01199654 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 6,886E-03 0,01198786 ! DNA replication initiation GO:0006270 27 16 0,000 6,886E-03 0,01197919 ! neuron recognition GO:0008038 35 16 0,000 6,886E-03 0,01197054 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 6,886E-03 0,01196189 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 6,886E-03 0,01195326 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 6,886E-03 0,01194464 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 6,886E-03 0,01193604 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 6,886E-03 0,01192744 ! sphingolipid catabolic process GO:0030149 27 16 0,000 6,886E-03 0,01191886 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 6,886E-03 0,0119103 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 6,886E-03 0,01190174 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 6,886E-03 0,0118932 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 6,886E-03 0,01188466 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 6,886E-03 0,01187614 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 6,886E-03 0,01186764 ! defense response to virus GO:0051607 37 16 0,000 6,886E-03 0,01185914 ! positive regulation of cell killing GO:0031343 32 17 0,000 7,315E-03 0,01258882 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 7,315E-03 0,01257982 ! metencephalon development GO:0022037 30 17 0,000 7,315E-03 0,01257083 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 7,315E-03 0,01256186 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 7,315E-03 0,0125529 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 7,315E-03 0,01254395 ! signal complex assembly GO:0007172 41 17 0,000 7,315E-03 0,01253502 ! endothelial cell migration GO:0043542 28 17 0,000 7,315E-03 0,0125261 ! inositol metabolic process GO:0006020 28 17 0,000 7,315E-03 0,01251719 ! gene silencing by RNA GO:0031047 36 17 0,000 7,315E-03 0,01250829 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 7,315E-03 0,01249941 ! glial cell development GO:0021782 27 17 0,000 7,315E-03 0,01249054 ! limbic system development GO:0021761 36 17 0,000 7,315E-03 0,01248168 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 7,315E-03 0,01247283 ! adult walking behavior GO:0007628 33 17 0,000 7,315E-03 0,012464 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 7,315E-03 0,01245518 ! heart looping GO:0001947 30 17 0,000 7,315E-03 0,01244637 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 7,315E-03 0,01243757 ! regulation of viral genome replication GO:0045069 28 17 0,000 7,315E-03 0,01242879 ! myoblast differentiation GO:0045445 45 17 0,000 7,315E-03 0,01242002 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 7,315E-03 0,01241126 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 7,315E-03 0,01240251 ! regulation of survival gene product expression GO:0045884 33 17 0,000 7,315E-03 0,01239378 ! cardiac muscle tissue development GO:0048738 31 17 0,000 7,315E-03 0,01238506 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 7,315E-03 0,01237635 ! glycine metabolic process GO:0006544 28 17 0,000 7,315E-03 0,01236765 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 7,315E-03 0,01235897 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 7,315E-03 0,01235029 ! NAD metabolic process GO:0019674 29 17 0,000 7,315E-03 0,01234163 ! membrane budding GO:0006900 37 17 0,000 7,315E-03 0,01233298 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 7,315E-03 0,01232435 ! regulation of protein binding GO:0043393 33 17 0,000 7,315E-03 0,01231572 ! nucleobase metabolic process GO:0009112 37 17 0,000 7,315E-03 0,01230711 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 7,315E-03 0,01229851 ! genitalia development GO:0048806 30 17 0,000 7,315E-03 0,01228992 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 7,315E-03 0,01228134 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 7,315E-03 0,01227278 ! neutrophil chemotaxis GO:0030593 27 17 0,000 7,315E-03 0,01226423 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 7,315E-03 0,01225569 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 7,315E-03 0,01224716 ! steroid catabolic process GO:0006706 31 17 0,000 7,315E-03 0,01223864 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 7,315E-03 0,01223014 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 7,315E-03 0,01222164 ! gas transport GO:0015669 25 17 0,000 7,315E-03 0,01221316 ! organic cation transport GO:0015695 31 17 0,000 7,315E-03 0,01220469 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 7,315E-03 0,01219624 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 7,315E-03 0,01218779 ! RNA 3'-end processing GO:0031123 34 17 0,000 7,315E-03 0,01217935 ! microspike assembly GO:0030035 36 17 0,000 7,315E-03 0,01217093 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 7,315E-03 0,01216252 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 7,315E-03 0,01215412 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 7,743E-03 0,01285763 ! neuron maturation GO:0042551 42 18 0,000 7,743E-03 0,01284876 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 7,743E-03 0,01283991 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 7,743E-03 0,01283106 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 7,743E-03 0,01282223 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 7,743E-03 0,01281341 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 7,743E-03 0,01280461 ! aminoglycan catabolic process GO:0006026 22 18 0,000 7,743E-03 0,01279581 ! memory GO:0007613 31 18 0,000 7,743E-03 0,01278703 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 7,743E-03 0,01277826 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 7,743E-03 0,0127695 ! patterning of blood vessels GO:0001569 39 18 0,000 7,743E-03 0,01276076 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 7,743E-03 0,01275202 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 7,743E-03 0,0127433 ! positive regulation of proteolysis GO:0045862 31 18 0,000 7,743E-03 0,01273459 ! epidermis morphogenesis GO:0048730 40 18 0,000 7,743E-03 0,01272589 ! glutamine metabolic process GO:0006541 29 18 0,000 7,743E-03 0,0127172 ! response to retinoic acid GO:0032526 26 18 0,000 7,743E-03 0,01270853 ! cell-substrate junction assembly GO:0007044 54 18 0,000 7,743E-03 0,01269987 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 7,743E-03 0,01269121 ! response to fungus GO:0009620 21 18 0,000 7,743E-03 0,01268257 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 7,743E-03 0,01267395 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 7,743E-03 0,01266533 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 7,743E-03 0,01265673 ! long-chain fatty acid transport GO:0015909 31 18 0,000 7,743E-03 0,01264813 ! peptide biosynthetic process GO:0043043 24 18 0,000 7,743E-03 0,01263955 ! vitamin transport GO:0051180 27 18 0,000 7,743E-03 0,01263098 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 7,743E-03 0,01262243 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 7,743E-03 0,01261388 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 7,743E-03 0,01260535 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 7,743E-03 0,01259682 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 7,743E-03 0,01258831 ! aromatic compound catabolic process GO:0019439 27 18 0,000 7,743E-03 0,01257981 ! nerve development GO:0021675 28 18 0,000 7,743E-03 0,01257132 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 7,743E-03 0,01256285 ! protein secretion GO:0009306 39 19 0,000 8,172E-03 0,01324921 ! positive regulation of translation GO:0045727 30 19 0,000 8,172E-03 0,01324029 ! negative regulation of defense response GO:0031348 25 19 0,000 8,172E-03 0,01323138 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 8,172E-03 0,01322248 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 8,172E-03 0,01321359 ! skin development GO:0043588 36 19 0,000 8,172E-03 0,01320472 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 8,172E-03 0,01319586 ! lipid phosphorylation GO:0046834 35 19 0,000 8,172E-03 0,01318701 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 8,172E-03 0,01317817 ! forelimb morphogenesis GO:0035136 32 19 0,000 8,172E-03 0,01316934 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 8,172E-03 0,01316053 ! bile acid metabolic process GO:0008206 29 19 0,000 8,172E-03 0,01315172 ! mitotic chromosome condensation GO:0007076 34 19 0,000 8,172E-03 0,01314293 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 8,172E-03 0,01313415 ! cerebral cortex development GO:0021987 36 19 0,000 8,172E-03 0,01312538 ! pigmentation during development GO:0048066 41 19 0,000 8,172E-03 0,01311663 ! response to vitamin A GO:0033189 27 19 0,000 8,172E-03 0,01310788 ! heme metabolic process GO:0042168 36 19 0,000 8,172E-03 0,01309915 ! actin filament bundle formation GO:0051017 42 19 0,000 8,172E-03 0,01309043 ! neuromuscular junction development GO:0007528 34 19 0,000 8,172E-03 0,01308172 ! response to lipopolysaccharide GO:0032496 30 19 0,000 8,172E-03 0,01307302 ! plasma membrane fusion GO:0045026 28 19 0,000 8,172E-03 0,01306434 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 8,172E-03 0,01305566 ! peptide cross-linking GO:0018149 37 19 0,000 8,172E-03 0,013047 ! protein export from nucleus GO:0006611 36 19 0,000 8,172E-03 0,01303835 ! heart process GO:0003015 30 19 0,000 8,172E-03 0,01302971 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 8,172E-03 0,01302108 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 8,172E-03 0,01301246 ! visual learning GO:0008542 36 19 0,000 8,172E-03 0,01300385 ! cellular pigmentation GO:0033059 36 19 0,000 8,172E-03 0,01299526 ! G1 phase GO:0051318 40 19 0,000 8,172E-03 0,01298668 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 8,172E-03 0,0129781 ! cell-cell junction organization GO:0045216 35 19 0,000 8,172E-03 0,01296954 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 8,172E-03 0,01296099 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 8,172E-03 0,01295245 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 8,172E-03 0,01294393 ! proximal/distal pattern formation GO:0009954 32 19 0,000 8,172E-03 0,01293541 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 8,172E-03 0,01292691 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 8,172E-03 0,01291841 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 8,172E-03 0,01290993 ! cilium assembly GO:0042384 37 19 0,000 8,172E-03 0,01290146 ! peptide hormone secretion GO:0030072 31 19 0,000 8,172E-03 0,012893 ! protein import into nucleus, docking GO:0000059 41 20 0,000 8,6E-03 0,01355999 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 8,6E-03 0,01355111 ! positive regulation of ossification GO:0045778 47 20 0,000 8,6E-03 0,01354224 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 8,6E-03 0,01353338 ! protein amino acid deacetylation GO:0006476 29 20 0,000 8,6E-03 0,01352454 ! protein amino acid acetylation GO:0006473 39 20 0,000 8,6E-03 0,0135157 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 8,6E-03 0,01350688 ! cAMP metabolic process GO:0046058 36 20 0,000 8,6E-03 0,01349807 ! response to vitamin GO:0033273 31 20 0,000 8,6E-03 0,01348927 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 8,6E-03 0,01348048 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 8,6E-03 0,01347171 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 8,6E-03 0,01346294 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 8,6E-03 0,01345419 ! response to alkaloid GO:0043279 38 20 0,000 8,6E-03 0,01344544 ! retinoid metabolic process GO:0001523 32 20 0,000 8,6E-03 0,01343671 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 8,6E-03 0,01342799 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 8,6E-03 0,01341929 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 8,6E-03 0,01341059 ! cellular response to starvation GO:0009267 33 20 0,000 8,6E-03 0,0134019 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 8,6E-03 0,01339323 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 8,6E-03 0,01338457 ! D-ribose metabolic process GO:0006014 29 20 0,000 8,6E-03 0,01337591 ! body fluid secretion GO:0007589 31 20 0,000 8,6E-03 0,01336727 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 8,6E-03 0,01335864 ! peptide secretion GO:0002790 35 20 0,000 8,6E-03 0,01335003 ! stem cell differentiation GO:0048863 53 20 0,000 8,6E-03 0,01334142 ! behavioral interaction between organisms GO:0051705 38 20 0,000 8,6E-03 0,01333282 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 8,6E-03 0,01332424 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 8,6E-03 0,01331566 ! sensory perception of pain GO:0019233 30 20 0,000 8,6E-03 0,0133071 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 8,6E-03 0,01329855 ! diencephalon development GO:0021536 34 20 0,000 8,6E-03 0,01329001 ! protein localization in mitochondrion GO:0070585 32 20 0,000 8,6E-03 0,01328148 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 8,6E-03 0,01327296 ! detection of chemical stimulus GO:0009593 37 20 0,000 8,6E-03 0,01326445 ! peptidyl-serine modification GO:0018209 43 20 0,000 8,6E-03 0,01325595 ! positive regulation of neurological system process GO:0031646 32 20 0,000 8,6E-03 0,01324746 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 8,6E-03 0,01323899 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 8,6E-03 0,01323052 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 8,6E-03 0,01322207 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 8,6E-03 0,01321363 ! regulation of glucose import GO:0046324 29 20 0,000 8,6E-03 0,01320519 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 8,6E-03 0,01319677 ! actin filament-based movement GO:0030048 43 20 0,000 8,6E-03 0,01318836 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 8,6E-03 0,01317996 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 8,6E-03 0,01317157 ! negative regulation of translation GO:0017148 29 20 0,000 8,6E-03 0,01316319 ! negative regulation of coagulation GO:0050819 29 20 0,000 8,6E-03 0,01315482 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 8,6E-03 0,01314647 ! regulation of cell killing GO:0031341 42 21 0,000 9,029E-03 0,01379228 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 9,029E-03 0,01378353 ! hormone secretion GO:0046879 38 21 0,000 9,029E-03 0,01377479 ! glycerol metabolic process GO:0006071 34 21 0,000 9,029E-03 0,01376606 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 9,029E-03 0,01375734 ! hindlimb morphogenesis GO:0035137 43 21 0,000 9,029E-03 0,01374863 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 9,029E-03 0,01373994 ! axis specification GO:0009798 38 21 0,000 9,029E-03 0,01373125 ! ovarian follicle development GO:0001541 35 21 0,000 9,029E-03 0,01372258 ! inactivation of MAPK activity GO:0000188 39 21 0,000 9,029E-03 0,01371392 ! smooth muscle contraction GO:0006939 46 21 0,000 9,029E-03 0,01370526 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 9,029E-03 0,01369662 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 9,029E-03 0,01368799 ! cell aging GO:0007569 44 21 0,000 9,029E-03 0,01367937 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 9,029E-03 0,01367076 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 9,029E-03 0,01366216 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 9,029E-03 0,01365358 ! cytolysis GO:0019835 24 21 0,000 9,029E-03 0,013645 ! vasodilation GO:0042311 39 21 0,000 9,029E-03 0,01363644 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 9,029E-03 0,01362788 ! regulation of vasoconstriction GO:0019229 39 21 0,000 9,029E-03 0,01361934 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 9,029E-03 0,0136108 ! oogenesis GO:0048477 36 21 0,000 9,029E-03 0,01360228 ! DNA modification GO:0006304 34 21 0,000 9,029E-03 0,01359377 ! positive regulation of locomotion GO:0040017 39 21 0,000 9,029E-03 0,01358527 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 9,029E-03 0,01357678 ! detection of biotic stimulus GO:0009595 29 21 0,000 9,029E-03 0,0135683 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 9,029E-03 0,01355983 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 9,029E-03 0,01355137 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 9,029E-03 0,01354292 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 9,029E-03 0,01353448 ! vitamin A metabolic process GO:0006776 33 21 0,000 9,029E-03 0,01352605 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 9,029E-03 0,01351764 ! response to cytokine stimulus GO:0034097 63 21 0,000 9,029E-03 0,01350923 ! terpenoid metabolic process GO:0006721 37 21 0,000 9,029E-03 0,01350083 ! collagen catabolic process GO:0030574 28 21 0,000 9,029E-03 0,01349245 ! sperm-egg recognition GO:0035036 21 21 0,000 9,029E-03 0,01348407 ! gut development GO:0048565 39 21 0,000 9,029E-03 0,01347571 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 9,457E-03 0,01410585 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 9,457E-03 0,01409711 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 9,457E-03 0,01408838 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 9,457E-03 0,01407966 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 9,457E-03 0,01407095 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 9,457E-03 0,01406226 ! regulation of chemotaxis GO:0050920 40 22 0,000 9,457E-03 0,01405357 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 9,457E-03 0,0140449 ! glutamate signaling pathway GO:0007215 41 22 0,000 9,457E-03 0,01403623 ! regeneration GO:0031099 41 22 0,000 9,457E-03 0,01402758 ! keratinization GO:0031424 28 22 0,000 9,457E-03 0,01401894 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 9,457E-03 0,0140103 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 9,457E-03 0,01400168 ! sensory perception of taste GO:0050909 28 22 0,000 9,457E-03 0,01399307 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 9,457E-03 0,01398447 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 9,457E-03 0,01397588 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 9,457E-03 0,0139673 ! vacuolar transport GO:0007034 36 22 0,000 9,457E-03 0,01395873 ! lysosome organization GO:0007040 41 22 0,000 9,457E-03 0,01395017 ! central nervous system neuron development GO:0021954 46 22 0,000 9,457E-03 0,01394163 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 9,457E-03 0,01393309 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 9,457E-03 0,01392456 ! fucose metabolic process GO:0006004 39 22 0,000 9,457E-03 0,01391604 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 9,457E-03 0,01390754 ! ureteric bud development GO:0001657 43 22 0,000 9,457E-03 0,01389904 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 9,457E-03 0,01389056 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 9,457E-03 0,01388208 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 9,457E-03 0,01387362 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 9,457E-03 0,01386516 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 9,457E-03 0,01385672 ! regulation of cytokine secretion GO:0050707 37 22 0,000 9,457E-03 0,01384829 ! sarcomere organization GO:0045214 30 22 0,000 9,457E-03 0,01383986 ! positive regulation of B cell activation GO:0050871 38 22 0,000 9,457E-03 0,01383145 ! activation of JUN kinase activity GO:0007257 42 22 0,000 9,457E-03 0,01382305 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 9,457E-03 0,01381465 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 9,457E-03 0,01380627 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 9,457E-03 0,0137979 ! protein stabilization GO:0050821 39 22 0,000 9,457E-03 0,01378953 ! positive regulation of DNA replication GO:0045740 43 23 0,000 9,885E-03 0,01440473 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 9,885E-03 0,01439601 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 9,885E-03 0,0143873 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 9,885E-03 0,01437861 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 9,885E-03 0,01436992 ! gluconeogenesis GO:0006094 33 23 0,000 9,885E-03 0,01436124 ! viral genome replication GO:0019079 41 23 0,000 9,885E-03 0,01435257 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 9,885E-03 0,01434392 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 9,885E-03 0,01433527 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 9,885E-03 0,01432663 ! glucosamine metabolic process GO:0006041 30 23 0,000 9,885E-03 0,01431801 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 9,885E-03 0,01430939 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 9,885E-03 0,01430079 ! visual behavior GO:0007632 42 23 0,000 9,885E-03 0,0142922 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 9,885E-03 0,01428361 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 9,885E-03 0,01427504 ! response to ethanol GO:0045471 46 23 0,000 9,885E-03 0,01426647 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 9,885E-03 0,01425792 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 9,885E-03 0,01424938 ! peroxisome organization GO:0007031 37 23 0,000 9,885E-03 0,01424085 ! polysaccharide catabolic process GO:0000272 27 23 0,000 9,885E-03 0,01423232 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 9,885E-03 0,01422381 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 9,885E-03 0,01421531 ! barbed-end actin filament capping GO:0051016 50 23 0,000 9,885E-03 0,01420682 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 9,885E-03 0,01419834 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 9,885E-03 0,01418986 ! regulation of viral reproduction GO:0050792 38 23 0,000 9,885E-03 0,0141814 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 9,885E-03 0,01417295 ! leukotriene metabolic process GO:0006691 42 23 0,000 9,885E-03 0,01416451 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 9,885E-03 0,01415608 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 9,885E-03 0,01414766 ! synaptic vesicle transport GO:0048489 46 23 0,000 9,885E-03 0,01413925 ! fatty acid transport GO:0015908 44 23 0,000 9,885E-03 0,01413085 ! platelet activation GO:0030168 37 23 0,000 9,885E-03 0,01412245 ! regulation of bone mineralization GO:0030500 49 23 0,000 9,885E-03 0,01411407 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 9,885E-03 0,0141057 ! hormone transport GO:0009914 40 23 0,000 9,885E-03 0,01409734 ! cell-cell recognition GO:0009988 25 23 0,000 9,885E-03 0,01408899 ! negative regulation of cytokine production GO:0001818 40 23 0,000 9,885E-03 0,01408065 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 9,885E-03 0,01407232 ! negative regulation of catabolic process GO:0009895 50 23 0,000 9,885E-03 0,01406399 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 9,885E-03 0,01405568 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 9,885E-03 0,01404738 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,01031225 0,01464657 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,01031225 0,01463793 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,01031225 0,01462929 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,01031225 0,01462067 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,01031225 0,01461206 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,01031225 0,01460346 ! vesicle docking GO:0048278 47 24 0,000 0,01031225 0,01459487 ! spinal cord development GO:0021510 47 24 0,000 0,01031225 0,01458629 ! vacuole organization GO:0007033 43 24 0,000 0,01031225 0,01457772 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,01031225 0,01456916 ! digestive system process GO:0022600 39 24 0,000 0,01031225 0,01456061 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,01031225 0,01455207 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,01031225 0,01454354 ! regulation of behavior GO:0050795 43 24 0,000 0,01031225 0,01453502 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,01031225 0,01452651 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,01031225 0,01451801 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,01031225 0,01450952 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,01031225 0,01450104 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,01031225 0,01449257 ! membrane depolarization GO:0051899 39 24 0,000 0,01031225 0,01448411 ! pallium development GO:0021543 49 24 0,000 0,01031225 0,01447566 ! pentose metabolic process GO:0019321 35 24 0,000 0,01031225 0,01446722 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,01031225 0,01445879 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,01031225 0,01445037 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,01031225 0,01444196 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,01031225 0,01443356 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,01031225 0,01442516 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,01031225 0,01441678 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,01031225 0,01440841 ! regulation of amine transport GO:0051952 40 24 0,000 0,01031225 0,01440005 ! protein tetramerization GO:0051262 52 24 0,000 0,01031225 0,0143917 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,01073979 0,01497968 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,01073979 0,014971 ! myelination GO:0042552 45 25 0,000 0,01073979 0,01496233 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,01073979 0,01495367 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,01073979 0,01494502 ! phototransduction GO:0007602 33 25 0,000 0,01073979 0,01493638 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,01073979 0,01492775 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,01073979 0,01491914 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,01073979 0,01491053 ! sperm motility GO:0030317 31 25 0,000 0,01073979 0,01490193 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,01073979 0,01489334 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,01073979 0,01488476 ! receptor metabolic process GO:0043112 46 25 0,000 0,01073979 0,01487619 ! chromosome condensation GO:0030261 45 25 0,000 0,01073979 0,01486763 ! response to starvation GO:0042594 42 25 0,000 0,01073979 0,01485908 ! osteoblast differentiation GO:0001649 60 25 0,000 0,01073979 0,01485054 ! neural crest cell development GO:0014032 54 25 0,000 0,01073979 0,01484201 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,01073979 0,01483349 ! negative regulation of cell development GO:0010721 73 25 0,000 0,01073979 0,01482498 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,01073979 0,01481648 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,01073979 0,01480799 ! interaction with host GO:0051701 62 25 0,000 0,01073979 0,01479951 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,01073979 0,01479104 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,01073979 0,01478258 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,01073979 0,01477412 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,01073979 0,01476568 ! immunoglobulin production GO:0002377 55 25 0,000 0,01073979 0,01475725 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,01073979 0,01474883 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,01073979 0,01474041 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,01073979 0,01473201 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,01073979 0,01472361 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,01073979 0,01471523 ! telomere organization GO:0032200 43 25 0,000 0,01073979 0,01470685 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,01073979 0,01469849 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,01073979 0,01469013 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,01116716 0,01526602 ! embryonic pattern specification GO:0009880 44 26 0,000 0,01116716 0,01525735 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,01116716 0,01524869 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,01116716 0,01524004 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,01116716 0,0152314 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,01116716 0,01522277 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,01116716 0,01521415 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,01116716 0,01520554 ! molting cycle process GO:0022404 50 26 0,000 0,01116716 0,01519694 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,01116716 0,01518835 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,01116716 0,01517977 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,01116716 0,0151712 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,01116716 0,01516264 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,01116716 0,01515408 GO:0051297|centrosome organization, ! insulin receptor signaling pathway GO:0008286 64 26 0,000 0,01116716 0,01514554 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,01116716 0,01513701 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,01116716 0,01512849 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,01116716 0,01511997 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,01116716 0,01511147 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,01116716 0,01510297 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,01116716 0,01509449 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,01116716 0,01508601 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,01116716 0,01507755 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,01116716 0,01506909 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,01116716 0,01506065 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,01116716 0,01505221 ! blastocyst development GO:0001824 49 26 0,000 0,01116716 0,01504378 ! leukocyte proliferation GO:0070661 52 26 0,000 0,01116716 0,01503536 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,01116716 0,01502695 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,01116716 0,01501855 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,01159436 0,01558437 ! neuron fate commitment GO:0048663 48 27 0,000 0,01159436 0,01557567 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,01159436 0,01556698 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,01159436 0,0155583 ! iron ion transport GO:0006826 59 27 0,000 0,01159436 0,01554963 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,01159436 0,01554096 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,01159436 0,01553231 ! protein amino acid acylation GO:0043543 55 27 0,000 0,01159436 0,01552367 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,01159436 0,01551503 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,01159436 0,01550641 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,01159436 0,0154978 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,01159436 0,01548919 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,01159436 0,01548059 ! autophagy GO:0006914 41 27 0,000 0,01159436 0,01547201 ! male gonad development GO:0008584 44 27 0,000 0,01159436 0,01546343 ! response to toxin GO:0009636 47 27 0,000 0,01159436 0,01545486 ! primary neural tube formation GO:0014020 51 27 0,000 0,01159436 0,01544631 ! base-excision repair GO:0006284 41 27 0,000 0,01159436 0,01543776 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,01159436 0,01542922 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,01159436 0,01542069 ! glutathione metabolic process GO:0006749 39 27 0,000 0,01159436 0,01541217 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,01159436 0,01540366 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,01159436 0,01539516 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,01159436 0,01538667 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,01202139 0,01594458 ! circadian rhythm GO:0007623 50 28 0,000 0,01202139 0,01593579 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,01202139 0,01592702 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,01202139 0,01591825 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,01202139 0,01590949 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,01202139 0,01590075 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,01202139 0,01589201 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,01202139 0,01588328 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,01202139 0,01587457 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,01202139 0,01586586 ! synaptogenesis GO:0007416 42 28 0,000 0,01202139 0,01585716 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,01202139 0,01584847 ! lipid oxidation GO:0034440 43 28 0,000 0,01202139 0,01583979 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,01202139 0,01583112 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,01202139 0,01582246 ! translational initiation GO:0006413 65 29 0,000 0,01244825 0,01637533 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,01244825 0,01636638 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,01244825 0,01635744 ! regulation of pH GO:0006885 43 29 0,000 0,01244825 0,01634852 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,01244825 0,0163396 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,01244825 0,01633069 ! catechol metabolic process GO:0009712 54 29 0,000 0,01244825 0,01632179 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,01244825 0,0163129 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,01244825 0,01630402 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,01244825 0,01629515 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,01244825 0,01628629 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,01244825 0,01627743 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,01244825 0,01626859 ! cell fate determination GO:0001709 60 29 0,000 0,01244825 0,01625976 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,01244825 0,01625094 ! detection of light stimulus GO:0009583 38 29 0,000 0,01244825 0,01624213 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 0,01244825 0,01623332 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,01244825 0,01622453 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,01244825 0,01621574 ! tissue homeostasis GO:0001894 48 29 0,000 0,01244825 0,01620697 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,01244825 0,0161982 ! phenol metabolic process GO:0018958 55 30 0,000 0,01287493 0,01674437 ! zinc ion transport GO:0006829 45 30 0,000 0,01287493 0,01673533 ! membrane docking GO:0022406 61 30 0,000 0,01287493 0,01672629 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,01287493 0,01671726 ! cell junction assembly GO:0034329 78 30 0,000 0,01287493 0,01670825 ! regulation of innate immune response GO:0045088 51 30 0,000 0,01287493 0,01669924 ! acute-phase response GO:0006953 49 30 0,000 0,01287493 0,01669024 ! myofibril assembly GO:0030239 47 30 0,000 0,01287493 0,01668125 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,01287493 0,01667228 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,01287493 0,01666331 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,01287493 0,01665435 ! phospholipid transport GO:0015914 51 30 0,000 0,01287493 0,0166454 ! ensheathment of neurons GO:0007272 57 30 0,000 0,01287493 0,01663646 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,01287493 0,01662753 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,01287493 0,01661861 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,01287493 0,0166097 ! eye morphogenesis GO:0048592 60 30 0,000 0,01287493 0,0166008 ! response to heat GO:0009408 50 30 0,000 0,01287493 0,01659191 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,01330145 0,01713238 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,01330145 0,01712322 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,01330145 0,01711406 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,01330145 0,01710491 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,01330145 0,01709578 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,01330145 0,01708665 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,01330145 0,01707753 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,01330145 0,01706842 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,01330145 0,01705932 ! ovulation cycle process GO:0022602 49 31 0,000 0,01330145 0,01705023 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,01330145 0,01704116 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,01330145 0,01703209 ! peptide transport GO:0015833 55 31 0,000 0,01330145 0,01702303 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,01330145 0,01701398 ! iron ion homeostasis GO:0055072 54 31 0,000 0,01330145 0,01700494 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,01330145 0,01699591 ! mesoderm formation GO:0001707 69 31 0,000 0,01330145 0,01698688 ! natural killer cell activation GO:0030101 45 31 0,000 0,01330145 0,01697787 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,01330145 0,01696887 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,01330145 0,01695988 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,01330145 0,0169509 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,01330145 0,01694192 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,01330145 0,01693296 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,0137278 0,01746646 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,0137278 0,01745723 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,0137278 0,01744801 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,0137278 0,0174388 ! cholesterol transport GO:0030301 56 32 0,000 0,0137278 0,01742959 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,0137278 0,0174204 ! spliceosome assembly GO:0000245 67 32 0,000 0,0137278 0,01741122 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,0137278 0,01740205 ! metanephros development GO:0001656 74 32 0,000 0,0137278 0,01739288 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,0137278 0,01738373 ! response to ionizing radiation GO:0010212 65 32 0,000 0,0137278 0,01737458 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,0137278 0,01736545 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,0137278 0,01735632 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,0137278 0,01734721 ! muscle cell development GO:0055001 49 32 0,000 0,0137278 0,0173381 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,0137278 0,017329 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,0137278 0,01731992 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,0137278 0,01731084 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,0137278 0,01730177 ! ovulation cycle GO:0042698 51 32 0,000 0,0137278 0,01729271 ! peripheral nervous system development GO:0007422 64 32 0,000 0,0137278 0,01728366 ! BMP signaling pathway GO:0030509 64 32 0,000 0,0137278 0,01727462 ! hindbrain development GO:0030902 61 32 0,000 0,0137278 0,01726559 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,0137278 0,01725657 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,0137278 0,01724756 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,0137278 0,01723856 ! gene silencing GO:0016458 65 32 0,000 0,0137278 0,01722957 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,01415398 0,0177552 ! post-embryonic development GO:0009791 69 33 0,000 0,01415398 0,01774594 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,01415398 0,0177367 ! protein targeting to membrane GO:0006612 68 33 0,000 0,01415398 0,01772747 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,01415398 0,01771824 ! ceramide metabolic process GO:0006672 64 33 0,000 0,01415398 0,01770903 ! formation of primary germ layer GO:0001704 72 33 0,000 0,01415398 0,01769983 ! cell fate specification GO:0001708 52 33 0,000 0,01415398 0,01769063 ! sterol transport GO:0015918 57 33 0,000 0,01415398 0,01768145 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,01415398 0,01767227 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,01415398 0,0176631 ! adult locomotory behavior GO:0008344 59 33 0,000 0,01415398 0,01765395 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,01415398 0,0176448 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,01415398 0,01763566 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,01457998 0,01815706 ! glial cell differentiation GO:0010001 63 34 0,000 0,01457998 0,01814767 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,01457998 0,01813828 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,01457998 0,01812891 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,01457998 0,01811954 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,01457998 0,01811019 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,01457998 0,01810085 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,01457998 0,01809151 ! mismatch repair GO:0006298 46 34 0,000 0,01457998 0,01808218 ! spermatid development GO:0007286 63 34 0,000 0,01457998 0,01807287 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,01457998 0,01806356 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,01457998 0,01805427 ! placenta development GO:0001890 53 34 0,000 0,01457998 0,01804498 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,01457998 0,0180357 ! regulation of muscle development GO:0048634 70 35 0,000 0,01500582 0,01855293 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,01500582 0,0185434 ! negative regulation of secretion GO:0051048 63 35 0,000 0,01500582 0,01853388 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,01500582 0,01852437 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,01500582 0,01851487 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,01500582 0,01850538 ! odontogenesis GO:0042476 66 35 0,000 0,01500582 0,0184959 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,01500582 0,01848643 ! female gonad development GO:0008585 58 35 0,000 0,01500582 0,01847697 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,01500582 0,01846752 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,01500582 0,01845808 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,01500582 0,01844865 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,01500582 0,01843922 ! cytokine production GO:0001816 59 35 0,000 0,01500582 0,01842981 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,01500582 0,01842041 ! neural tube formation GO:0001841 67 35 0,000 0,01500582 0,01841102 ! vesicle localization GO:0051648 64 35 0,000 0,01500582 0,01840163 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,01543149 0,01891399 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,01543149 0,01890436 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,01543149 0,01889474 ! cell junction organization GO:0034330 86 36 0,000 0,01543149 0,01888513 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,01543149 0,01887552 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,01543149 0,01886593 ! positive regulation of cell development GO:0010720 80 36 0,000 0,01543149 0,01885635 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,01543149 0,01884678 ! regulation of proteolysis GO:0030162 72 36 0,000 0,01543149 0,01883722 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,01543149 0,01882767 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,01543149 0,01881812 ! aerobic respiration GO:0009060 55 36 0,000 0,01543149 0,01880859 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,01543149 0,01879907 ! embryonic organ development GO:0048568 57 36 0,000 0,01543149 0,01878955 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,01543149 0,01878005 ! RNA export from nucleus GO:0006405 56 37 0,000 0,01585698 0,01928812 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,01585698 0,01927838 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,01585698 0,01926864 ! actomyosin structure organization GO:0031032 62 37 0,000 0,01585698 0,01925891 ! organic anion transport GO:0015711 68 37 0,000 0,01585698 0,01924919 ! tissue remodeling GO:0048771 76 37 0,000 0,01585698 0,01923949 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,01585698 0,01922979 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,01585698 0,0192201 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,01585698 0,01921043 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,01585698 0,01920076 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,01585698 0,0191911 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,01585698 0,01918145 ! glycogen metabolic process GO:0005977 61 37 0,000 0,01585698 0,01917181 ! pigment metabolic process GO:0042440 80 37 0,000 0,01585698 0,01916218 ! spermatid differentiation GO:0048515 66 37 0,000 0,01585698 0,01915256 ! cellular response to insulin stimulus GO:0032869 82 37 0,000 0,01585698 0,01914295 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,01628231 0,01964656 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,01628231 0,01963671 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,01628231 0,01962688 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,01628231 0,01961705 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,01628231 0,01960723 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,01628231 0,01959742 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,01628231 0,01958762 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 67 38 0,000 0,01628231 0,01957783 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,01628231 0,01956805 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,01628231 0,01955828 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,01628231 0,01954852 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,01628231 0,01953877 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,01628231 0,01952903 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,01628231 0,0195193 ! glucan metabolic process GO:0044042 62 38 0,000 0,01628231 0,01950958 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,01670747 0,02000905 ! mammary gland development GO:0030879 86 39 0,000 0,01670747 0,01999909 ! learning GO:0007612 77 39 0,000 0,01670747 0,01998915 ! ear morphogenesis GO:0042471 60 39 0,000 0,01670747 0,01997921 ! organic ether metabolic process GO:0018904 55 39 0,000 0,01670747 0,01996929 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,01670747 0,01995937 ! segmentation GO:0035282 67 39 0,000 0,01670747 0,01994947 ! ion transmembrane transport GO:0034220 66 39 0,000 0,01670747 0,01993957 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,01670747 0,01992968 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,01670747 0,01991981 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,01670747 0,01990994 ! RNA modification GO:0009451 57 39 0,000 0,01670747 0,01990009 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,01670747 0,01989024 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,01713246 0,0203861 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,01713246 0,02037602 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,01713246 0,02036596 ! feeding behavior GO:0007631 59 40 0,000 0,01713246 0,0203559 ! negative regulation of binding GO:0051100 72 40 0,000 0,01713246 0,02034585 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,01713246 0,02033581 ! mesenchymal cell development GO:0014031 87 40 0,000 0,01713246 0,02032579 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,01713246 0,02031577 ! maintenance of protein location GO:0045185 91 40 0,000 0,01713246 0,02030576 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,01755728 0,02079902 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,01755728 0,02078878 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,01755728 0,02077856 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,01755728 0,02076834 ! gliogenesis GO:0042063 88 41 0,000 0,01755728 0,02075814 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,01755728 0,02074794 ! T cell differentiation GO:0030217 81 41 0,000 0,01755728 0,02073776 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,01755728 0,02072758 ! female gamete generation GO:0007292 61 41 0,000 0,01755728 0,02071742 ! polyol metabolic process GO:0019751 66 41 0,000 0,01755728 0,02070726 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,01755728 0,02069711 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,01798193 0,02118732 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,01798193 0,02117695 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,01798193 0,02116659 ! regulation of tube size GO:0035150 71 42 0,000 0,01798193 0,02115624 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,01798193 0,0211459 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,01798193 0,02113557 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,01798193 0,02112525 ! regulation of intracellular protein transport GO:0033157 80 42 0,000 0,01798193 0,02111494 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,01798193 0,02110464 ! neuron migration GO:0001764 79 42 0,000 0,01798193 0,02109435 ! regulation of protein secretion GO:0050708 71 42 0,000 0,01798193 0,02108407 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,01798193 0,0210738 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,01840641 0,02156077 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,01840641 0,02155028 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,01840641 0,02153979 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,01840641 0,02152932 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,01840641 0,02151886 ! glucose transport GO:0015758 65 43 0,000 0,01840641 0,02150841 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,01840641 0,02149797 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,01840641 0,02148754 ! neural tube development GO:0021915 77 43 0,000 0,01840641 0,02147712 ! regulation of epithelial cell proliferation GO:0050678 111 43 0,000 0,01840641 0,02146671 ! striated muscle contraction GO:0006941 77 43 0,000 0,01840641 0,02145631 ! phagocytosis GO:0006909 90 43 0,000 0,01840641 0,02144592 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,01840641 0,02143553 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,01883072 0,02191906 ! hexose transport GO:0008645 67 44 0,000 0,01883072 0,02190847 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,01883072 0,02189788 ! male sex differentiation GO:0046661 76 44 0,000 0,01883072 0,0218873 ! biopolymer methylation GO:0043414 84 44 0,000 0,01883072 0,02187673 ! B cell differentiation GO:0030183 107 44 0,000 0,01883072 0,02186617 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,01883072 0,02185562 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,01883072 0,02184509 ! developmental growth GO:0048589 82 44 0,000 0,01883072 0,02183456 ! maintenance of location in cell GO:0051651 97 44 0,000 0,01883072 0,02182404 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,01925486 0,02230486 ! glycolysis GO:0006096 65 45 0,000 0,01925486 0,02229412 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,01925486 0,0222834 ! leukocyte migration GO:0050900 68 45 0,000 0,01925486 0,02227269 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,01925486 0,02226198 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,01925486 0,02225129 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,01925486 0,02224061 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,01925486 0,02222994 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,01925486 0,02221928 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,01925486 0,02220862 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,01925486 0,02219798 ! cell growth GO:0016049 84 45 0,000 0,01925486 0,02218735 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,01967883 0,02266504 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 0,000 0,01967883 0,02265419 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,01967883 0,02264336 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,01967883 0,02263254 ! pigmentation GO:0043473 100 46 0,000 0,01967883 0,02262172 ! response to insulin stimulus GO:0032868 95 46 0,000 0,01967883 0,02261092 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,01967883 0,02260013 ! positive regulation of defense response GO:0031349 76 47 0,000 0,02010263 0,02307583 ! endosome transport GO:0016197 108 47 0,000 0,02010263 0,02306482 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,02010263 0,02305383 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,02010263 0,02304285 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,02010263 0,02303187 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,02010263 0,02302091 ! JNK cascade GO:0007254 91 47 0,000 0,02010263 0,02300996 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,02010263 0,02299902 ! methylation GO:0032259 90 47 0,000 0,02010263 0,02298809 ! mitochondrial transport GO:0006839 82 48 0,000 0,02052627 0,02346138 ! Notch signaling pathway GO:0007219 96 48 0,000 0,02052627 0,02345024 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,02052627 0,02343911 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,02052627 0,02342799 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,02052627 0,02341688 ! activation of caspase activity GO:0006919 84 48 0,000 0,02052627 0,02340578 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,02052627 0,02339469 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,02052627 0,02338362 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,02052627 0,02337255 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,02094973 0,02384345 ! regulation of action potential GO:0001508 95 49 0,000 0,02094973 0,02383218 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,02094973 0,02382091 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,02094973 0,02380966 ! regulation of ion transport GO:0043269 77 49 0,000 0,02094973 0,02379842 ! peptide metabolic process GO:0006518 76 49 0,000 0,02094973 0,02378719 ! response to temperature stimulus GO:0009266 76 49 0,000 0,02094973 0,02377597 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,02094973 0,02376476 ! endocrine system development GO:0035270 104 49 0,000 0,02094973 0,02375356 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,02094973 0,02374237 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,02094973 0,02373119 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,02094973 0,02372003 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,02137303 0,02418791 ! neuromuscular process GO:0050905 99 50 0,000 0,02137303 0,02417654 ! regulation of ossification GO:0030278 117 50 0,000 0,02137303 0,02416518 ! inner ear development GO:0048839 79 50 0,000 0,02137303 0,02415383 ! histone modification GO:0016570 91 50 0,000 0,02137303 0,02414249 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,02137303 0,02413116 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,02137303 0,02411984 ! positive regulation of binding GO:0051099 78 51 0,000 0,02179615 0,02458582 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,02179615 0,0245743 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,02179615 0,02456279 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,02179615 0,02455129 ! excretion GO:0007588 83 51 0,000 0,02179615 0,0245398 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,02179615 0,02452832 ! chromatin remodeling GO:0006338 109 51 0,000 0,02179615 0,02451685 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,02179615 0,0245054 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,02179615 0,02449395 ! vesicle organization GO:0016050 107 51 0,000 0,02179615 0,02448252 ! regulation of cell shape GO:0008360 125 51 0,000 0,02179615 0,02447109 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,02179615 0,02445968 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,02221911 0,0249227 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,02221911 0,02491108 ! membrane fusion GO:0006944 110 52 0,000 0,02221911 0,02489948 ! positive regulation of growth GO:0045927 90 52 0,000 0,02221911 0,02488789 ! covalent chromatin modification GO:0016569 101 52 0,000 0,02221911 0,02487631 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,02221911 0,02486474 ! amino acid activation GO:0043038 92 52 0,000 0,02221911 0,02485318 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,02221911 0,02484163 ! synapse organization GO:0050808 85 52 0,000 0,02221911 0,02483009 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,0226419 0,02529081 ! RNA catabolic process GO:0006401 93 53 0,000 0,0226419 0,02527908 ! regulation of translational initiation GO:0006446 82 53 0,000 0,0226419 0,02526735 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,0226419 0,02525564 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,0226419 0,02524394 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,0226419 0,02523224 ! cell maturation GO:0048469 100 53 0,000 0,0226419 0,02522056 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,0226419 0,02520889 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,0226419 0,02519723 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,02306452 0,02565568 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,02306452 0,02564383 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,02306452 0,02563198 ! cell recognition GO:0008037 85 54 0,000 0,02306452 0,02562015 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,02306452 0,02560832 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,02306452 0,02559651 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,02306452 0,02558471 ! chloride transport GO:0006821 90 55 0,000 0,02348697 0,02604132 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,02348697 0,02602932 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,02348697 0,02601734 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,02348697 0,02600536 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,02348697 0,0259934 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,02348697 0,02598145 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,02348697 0,02596951 ! aging GO:0007568 103 55 0,000 0,02348697 0,02595758 ! gastrulation GO:0007369 112 55 0,000 0,02348697 0,02594566 ! heart morphogenesis GO:0003007 97 55 0,000 0,02348697 0,02593376 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,02348697 0,02592186 ! RNA elongation GO:0006354 79 55 0,000 0,02348697 0,02590998 ! nuclear export GO:0051168 97 55 0,000 0,02348697 0,0258981 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,02348697 0,02588624 ! regulation of actin filament length GO:0030832 105 56 0,000 0,02390926 0,02633959 ! sensory perception of smell GO:0007608 80 56 0,000 0,02390926 0,02632754 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,02390926 0,02631549 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,02390926 0,02630346 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,02390926 0,02629144 ! regulation of DNA replication GO:0006275 101 56 0,000 0,02390926 0,02627943 ! proton transport GO:0015992 94 56 0,000 0,02390926 0,02626743 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,02433137 0,02671898 ! muscle fiber development GO:0048747 112 57 0,000 0,02433137 0,02670679 ! positive regulation of cell migration GO:0030335 126 57 0,000 0,02433137 0,02669461 ! lipid modification GO:0030258 97 57 0,000 0,02433137 0,02668244 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,02433137 0,02667029 ! regulation of intracellular transport GO:0032386 101 57 0,000 0,02433137 0,02665814 ! maintenance of location GO:0051235 118 57 0,000 0,02433137 0,02664601 ! hydrogen transport GO:0006818 97 58 0,000 0,02475332 0,02709576 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,02475332 0,02708344 ! regulation of endocytosis GO:0030100 91 58 0,000 0,02475332 0,02707113 ! adult behavior GO:0030534 99 58 0,000 0,02475332 0,02705883 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,02475332 0,02704654 ! positive regulation of secretion GO:0051047 95 59 0,000 0,02517509 0,0274949 ! regulation of cellular component size GO:0032535 109 59 0,000 0,02517509 0,02748243 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,02517509 0,02746997 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,02517509 0,02745751 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,02517509 0,02744507 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,02517509 0,02743264 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,0255967 0,02787943 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,0255967 0,02786682 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,0255967 0,02785421 ! regulation of heart contraction GO:0008016 110 60 0,000 0,0255967 0,02784162 ! camera-type eye development GO:0043010 116 60 0,000 0,0255967 0,02782904 ! protein amino acid autophosphorylation GO:0046777 141 60 0,000 0,0255967 0,02781647 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,0255967 0,02780391 ! kidney development GO:0001822 122 60 0,000 0,0255967 0,02779137 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,02601814 0,0282362 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,02601814 0,02822347 ! mesoderm development GO:0007498 119 61 0,000 0,02601814 0,02821075 ! tRNA processing GO:0008033 89 61 0,000 0,02601814 0,02819804 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,02601814 0,02818535 ! response to peptide hormone stimulus GO:0043434 122 61 0,000 0,02601814 0,02817266 ! ear development GO:0043583 103 62 0,000 0,02643942 0,02861594 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,02643942 0,02860307 ! gonad development GO:0008406 98 62 0,000 0,02643942 0,02859022 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,02643942 0,02857737 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,02686052 0,02901949 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,02686052 0,02900647 ! detection of external stimulus GO:0009581 91 63 0,000 0,02686052 0,02899345 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,02686052 0,02898045 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,02686052 0,02896746 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,02728146 0,02940824 ! cell redox homeostasis GO:0045454 102 64 0,000 0,02728146 0,02939507 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,02728146 0,02938191 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,02728146 0,02936876 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,02728146 0,02935563 ! positive regulation of cell motion GO:0051272 146 64 0,000 0,02728146 0,0293425 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,02770222 0,02978175 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,02770222 0,02976845 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,02770222 0,02975516 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,02770222 0,02974188 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,02770222 0,02972861 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,02812282 0,03016652 ! actin filament organization GO:0007015 148 66 0,000 0,02812282 0,03015308 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,02812282 0,03013965 ! extracellular matrix organization GO:0030198 133 66 0,000 0,02812282 0,03012623 ! secondary metabolic process GO:0019748 116 66 0,000 0,02812282 0,03011282 ! developmental maturation GO:0021700 116 66 0,000 0,02812282 0,03009943 ! cell projection assembly GO:0030031 120 66 0,000 0,02812282 0,03008604 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,02854326 0,03052226 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,02854326 0,0305087 ! negative regulation of cell growth GO:0030308 132 67 0,000 0,02854326 0,03049515 ! activation of MAPK activity GO:0000187 115 67 0,000 0,02854326 0,03048161 ! lung development GO:0030324 144 67 0,000 0,02854326 0,03046809 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,02854326 0,03045458 ! hexose catabolic process GO:0019320 104 67 0,000 0,02854326 0,03044108 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,02854326 0,03042759 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,02854326 0,03041412 ! adaptive immune response GO:0002250 119 67 0,000 0,02854326 0,03040065 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,02854326 0,0303872 ! amino acid transport GO:0006865 125 68 0,000 0,02896352 0,03082098 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,02896352 0,03080735 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,02896352 0,03079374 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,02896352 0,03078014 ! regulation of lipase activity GO:0060191 130 68 0,000 0,02896352 0,03076655 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,02896352 0,03075297 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,02938362 0,03118526 ! negative regulation of cell size GO:0045792 134 69 0,000 0,02938362 0,03117151 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,02938362 0,03115777 ! urogenital system development GO:0001655 137 69 0,000 0,02938362 0,03114404 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,02938362 0,03113033 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,02938362 0,03111663 ! antigen processing and presentation GO:0019882 104 69 0,000 0,02938362 0,03110294 ! appendage morphogenesis GO:0035107 135 70 0,000 0,02980355 0,03153357 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 0,000 0,02980355 0,03151971 ! amine catabolic process GO:0009310 117 71 0,000 0,03022331 0,03194959 ! reproductive structure development GO:0048608 113 71 0,000 0,03022331 0,03193556 ! appendage development GO:0048736 136 71 0,000 0,03022331 0,03192154 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,03022331 0,03190754 ! B cell activation GO:0042113 160 71 0,000 0,03022331 0,03189354 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,03022331 0,03187956 ! regulation of immune effector process GO:0002697 137 71 0,000 0,03022331 0,03186559 ! acute inflammatory response GO:0002526 113 72 0,000 0,0306429 0,03229383 ! regulation of caspase activity GO:0043281 122 72 0,000 0,0306429 0,03227969 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,0306429 0,03226556 ! carbohydrate transport GO:0008643 110 72 0,000 0,0306429 0,03225145 ! respiratory system development GO:0060541 153 72 0,000 0,0306429 0,03223735 ! learning or memory GO:0007611 147 73 0,000 0,03106232 0,03266432 ! regulation of blood pressure GO:0008217 125 73 0,000 0,03106232 0,03265005 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,03106232 0,03263579 ! axon guidance GO:0007411 139 73 0,000 0,03106232 0,03262154 ! fertilization GO:0009566 90 73 0,000 0,03106232 0,03260731 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,03148158 0,03303301 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,03148158 0,03301861 ! neurotransmitter transport GO:0006836 123 74 0,000 0,03148158 0,03300422 ! exocytosis GO:0006887 133 74 0,000 0,03148158 0,03298985 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,03148158 0,03297548 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,03148158 0,03296114 ! regulation of endopeptidase activity GO:0052548 125 74 0,000 0,03148158 0,0329468 ! eye development GO:0001654 143 74 0,000 0,03148158 0,03293247 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,03190067 0,03335638 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,03190067 0,03334189 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,03190067 0,03332741 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,03190067 0,03331294 ! rhythmic process GO:0048511 128 75 0,000 0,03190067 0,03329849 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,03190067 0,03328405 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,0323196 0,03370652 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,0323196 0,03369192 ! defense response to bacterium GO:0042742 89 76 0,000 0,0323196 0,03367733 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,0323196 0,03366275 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,0323196 0,03364818 ! regulation of catabolic process GO:0009894 161 76 0,000 0,0323196 0,03363363 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,03273835 0,03405468 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,03273835 0,03403996 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,03273835 0,03402526 ! blood coagulation GO:0007596 146 78 0,000 0,03315694 0,03444542 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,03315694 0,03443056 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,03315694 0,0344157 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,03357536 0,03483498 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,03357536 0,03481997 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,03357536 0,03480496 ! regulation of peptidase activity GO:0052547 134 79 0,000 0,03357536 0,03478998 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,03357536 0,034775 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,03399362 0,03519305 ! muscle cell differentiation GO:0042692 159 80 0,000 0,03399362 0,03517791 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,03399362 0,03516279 ! protein import into nucleus GO:0006606 158 80 0,000 0,03399362 0,03514768 ! inorganic anion transport GO:0015698 138 80 0,000 0,03399362 0,03513258 ! T cell activation GO:0042110 168 81 0,000 0,0344117 0,0355494 ! response to hypoxia GO:0001666 171 81 0,000 0,0344117 0,03553415 ! digestion GO:0007586 112 81 0,000 0,0344117 0,0355189 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,0344117 0,03550367 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,0344117 0,03548845 ! nuclear import GO:0051170 161 81 0,000 0,0344117 0,03547325 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,0344117 0,03545806 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,03482962 0,03587332 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,03482962 0,03585797 ! response to drug GO:0042493 143 82 0,000 0,03482962 0,03584263 ! response to nutrient GO:0007584 125 82 0,000 0,03482962 0,03582731 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,03482962 0,035812 ! cellular response to hormone stimulus GO:0032870 167 82 0,000 0,03482962 0,0357967 ! response to oxygen levels GO:0070482 176 83 0,000 0,03524738 0,03621058 ! regulation of lyase activity GO:0051339 160 83 0,000 0,03524738 0,03619513 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,03566496 0,03660832 ! hemostasis GO:0007599 158 84 0,000 0,03566496 0,03659271 ! negative regulation of transport GO:0051051 153 84 0,000 0,03566496 0,03657711 ! negative regulation of growth GO:0045926 155 84 0,000 0,03566496 0,03656153 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,03566496 0,03654595 ! nucleosome assembly GO:0006334 122 85 0,000 0,03608238 0,03695794 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,03608238 0,03694222 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,03608238 0,0369265 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,03649964 0,03733764 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,03649964 0,03732177 ! chromatin assembly GO:0031497 124 86 0,000 0,03649964 0,03730591 ! tube morphogenesis GO:0035239 176 86 0,000 0,03649964 0,03729007 ! alcohol catabolic process GO:0046164 130 86 0,000 0,03649964 0,03727425 ! amine transport GO:0015837 155 86 0,000 0,03649964 0,03725843 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,03691672 0,03766821 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,03691672 0,03765224 ! protein localization in nucleus GO:0034504 176 87 0,000 0,03691672 0,03763628 ! regulation of protein transport GO:0051223 154 87 0,000 0,03691672 0,03762034 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 135 88 0,000 0,03733364 0,0380291 ! regulation of DNA binding GO:0051101 155 88 0,000 0,03733364 0,03801301 ! gland development GO:0048732 206 88 0,000 0,03733364 0,03799693 ! regulation of neurological system process GO:0031644 148 88 0,000 0,03733364 0,03798086 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,03733364 0,03796481 ! cellular defense response GO:0006968 114 89 0,000 0,03775039 0,03837239 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,03775039 0,03835618 ! regulation of cell adhesion GO:0030155 212 89 0,000 0,03775039 0,03833999 ! ossification GO:0001503 188 90 0,000 0,03816698 0,03874673 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,03816698 0,03873039 ! sex differentiation GO:0007548 145 90 0,000 0,03816698 0,03871406 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,03816698 0,03869775 ! bone development GO:0060348 189 91 0,000 0,0385834 0,03910348 ! sterol metabolic process GO:0016125 152 91 0,000 0,0385834 0,03908701 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,0385834 0,03907056 ! regulation of defense response GO:0031347 149 92 0,000 0,03899965 0,03947546 ! nucleosome organization GO:0034728 138 92 0,000 0,03899965 0,03945886 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,03899965 0,03944227 ! vitamin metabolic process GO:0006766 139 92 0,000 0,03899965 0,0394257 ! positive regulation of MAP kinase activity GO:0043406 160 93 0,000 0,03941574 0,0398296 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,03941574 0,03981287 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,03941574 0,03979617 ! regulation of membrane potential GO:0042391 164 93 0,000 0,03941574 0,03977947 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,03941574 0,03976279 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,03983166 0,04016554 ! female pregnancy GO:0007565 164 94 0,000 0,03983166 0,04014871 ! transcription initiation GO:0006352 153 94 0,000 0,03983166 0,0401319 ! forebrain development GO:0030900 188 95 0,000 0,04024741 0,04053381 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,04024741 0,04051685 ! leukocyte differentiation GO:0002521 202 96 0,000 0,040663 0,0409181 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,040663 0,04090099 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,040663 0,0408839 ! positive regulation of immune response GO:0050778 156 96 0,000 0,040663 0,04086683 ! detection of stimulus GO:0051606 151 96 0,000 0,040663 0,04084976 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,04107842 0,04124987 ! protein ubiquitination GO:0016567 217 97 0,000 0,04107842 0,04123266 ! hormone metabolic process GO:0042445 157 97 0,000 0,04107842 0,04121547 ! regulation of protein localization GO:0032880 176 97 0,000 0,04107842 0,04119828 ! response to virus GO:0009615 160 98 0,000 0,04149368 0,04159741 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,04149368 0,04158009 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,04149368 0,04156278 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,04190877 0,04196109 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,04190877 0,04194363 ! skeletal muscle tissue development GO:0007519 186 99 0,000 0,04190877 0,04192619 GO:0060538|skeletal muscle organ development, ! cell cycle arrest GO:0007050 213 100 0,000 0,04232369 0,04232369