pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-b2/out-0.05-06-0.01-300-run-b2//th1-pval-1e-01-06-th2-pval-1e-02-02-th3-pval-1e-01-01-run-b2/go_data/10726-0-real-Loi_GPL96-GPL97-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! spindle assembly GO:0051225 6 5 3,000 7,065E-13 1,7E-09 ! natural killer cell mediated immunity GO:0002228 18 10 3,000 2,961E-11 3,562E-08 GO:0042267|natural killer cell mediated cytotoxicity, ! leukocyte mediated cytotoxicity GO:0001909 26 12 3,000 6,974E-11 5,593E-08 ! cell killing GO:0001906 29 15 3,000 1,921E-10 1,155E-07 ! polyol catabolic process GO:0046174 7 5 2,000 2,502E-09 1,204E-06 GO:0019405|alditol catabolic process, ! spindle organization GO:0007051 46 32 3,000 5,023E-09 2,014E-06 ! cellular carbohydrate catabolic process GO:0044275 15 13 2,000 7,132E-08 2,451E-05 ! lymphocyte mediated immunity GO:0002449 114 64 3,000 8,756E-08 2,633E-05 ! fructose metabolic process GO:0006000 25 16 2,000 1,395E-07 3,728E-05 ! leukocyte mediated immunity GO:0002443 128 74 3,000 1,579E-07 3,799E-05 ! alditol metabolic process GO:0019400 38 24 2,000 5,024E-07 1,099E-04 ! sperm motility GO:0030317 31 25 2,000 5,706E-07 1,144E-04 ! hexose biosynthetic process GO:0019319 48 32 2,000 1,227E-06 2,271E-04 ! monosaccharide biosynthetic process GO:0046364 52 36 2,000 1,763E-06 3,03E-04 ! polyol metabolic process GO:0019751 66 41 2,000 2,627E-06 4,213E-04 ! alcohol biosynthetic process GO:0046165 59 42 2,000 2,828E-06 4,252E-04 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 2,000 7,162E-06 1,014E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 1,17E-05 1,564E-03 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 2,000 1,276E-05 1,616E-03 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 2,000 1,45E-05 1,745E-03 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 2,000 1,45E-05 1,662E-03 ! positive regulation of ligase activity GO:0051351 124 77 2,000 1,775E-05 1,942E-03 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 2,000 1,918E-05 2,006E-03 ! regulation of ligase activity GO:0051340 142 84 2,000 2,306E-05 2,311E-03 ! alcohol catabolic process GO:0046164 130 86 2,000 2,474E-05 2,381E-03 ! carbohydrate biosynthetic process GO:0016051 141 93 2,000 3,128E-05 2,895E-03 ! cellular response to unfolded protein GO:0034620 33 19 1,000 7,116E-05 6,341E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 1,245E-04 0,01070172 ! fat cell differentiation GO:0045444 50 27 1,000 1,456E-04 0,01207962 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 1,567E-04 0,01257019 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 1,000 4,261E-04 0,03307022 ! response to calcium ion GO:0051592 81 47 1,000 4,449E-04 0,03344731 ! positive regulation of cell cycle GO:0045787 89 48 1,000 4,64E-04 0,03383045 ! response to UV GO:0009411 104 53 1,000 5,657E-04 0,04003304 ! regulation of mitosis GO:0007088 105 63 1,000 7,986E-04 0,05489767 GO:0051783|regulation of nuclear division, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 9,296E-04 0,06213079 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 1,000 1,041E-03 0,06772104 ! steroid biosynthetic process GO:0006694 131 76 1,000 1,159E-03 0,07340652 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 1,252E-03 0,07722932 ! response to metal ion GO:0010038 140 80 1,000 1,283E-03 0,0771986 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 1,315E-03 0,07719173 GO:0045937|positive regulation of phosphate metabolic process, ! response to unfolded protein GO:0006986 131 85 1,000 1,447E-03 0,08289677 ! response to inorganic substance GO:0010035 153 86 1,000 1,481E-03 0,0828638 ! positive regulation of protein modification process GO:0031401 136 88 1,000 1,55E-03 0,08474611 ! regulation of cell cycle process GO:0010564 149 90 1,000 1,62E-03 0,08662537 ! response to protein stimulus GO:0051789 149 91 1,000 1,656E-03 0,08661208 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 1,729E-03 0,08848709 GO:0010498|proteasomal protein catabolic process, ! interphase of mitotic cell cycle GO:0051329 209 95 1,000 1,803E-03 0,09035909 ! interphase GO:0051325 213 98 1,000 1,917E-03 0,09411207 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 3,316E-03 0,15957539 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 3,316E-03 0,15644646 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 3,316E-03 0,15343787 ! positive regulation of helicase activity GO:0051096 11 5 0,000 3,316E-03 0,15054282 ! neuron fate determination GO:0048664 7 5 0,000 3,316E-03 0,14775499 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 3,316E-03 0,14506853 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 3,316E-03 0,14247802 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 3,316E-03 0,13997841 ! polyol transport GO:0015791 12 5 0,000 3,316E-03 0,13756499 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 3,316E-03 0,13523338 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 3,316E-03 0,13297949 ! response to superoxide GO:0000303 10 5 0,000 3,316E-03 0,1307995 ! negative regulation of bone resorption GO:0045779 10 5 0,000 3,316E-03 0,12868983 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 3,316E-03 0,12664713 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 3,316E-03 0,12466827 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 3,316E-03 0,1227503 ! female meiosis GO:0007143 7 5 0,000 3,316E-03 0,12089044 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 3,316E-03 0,11908611 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 3,316E-03 0,11733484 ! cobalt ion transport GO:0006824 11 5 0,000 3,316E-03 0,11563434 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 3,316E-03 0,11398242 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 3,316E-03 0,11237703 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 3,316E-03 0,11081624 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 3,316E-03 0,10929821 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 3,316E-03 0,10782121 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 3,316E-03 0,10638359 ! embryonic camera-type eye development GO:0031076 10 5 0,000 3,316E-03 0,10498381 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 3,316E-03 0,10362038 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 3,316E-03 0,10229191 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 3,316E-03 0,10099708 ! adaptation of signaling pathway GO:0022401 7 5 0,000 3,316E-03 0,09973462 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 3,316E-03 0,09850332 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 3,316E-03 0,09730206 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 3,316E-03 0,09612975 ! negative chemotaxis GO:0050919 14 5 0,000 3,316E-03 0,09498535 ! positive regulation of histone modification GO:0031058 5 5 0,000 3,316E-03 0,09386787 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 3,316E-03 0,09277639 ! sensory perception of bitter taste GO:0050913 7 5 0,000 3,316E-03 0,09170999 ! behavioral response to pain GO:0048266 9 5 0,000 3,316E-03 0,09066783 ! clathrin coat assembly GO:0048268 14 5 0,000 3,316E-03 0,08964909 ! Notch receptor processing GO:0007220 8 5 0,000 3,316E-03 0,08865299 ! regulation of dopamine uptake GO:0051584 9 5 0,000 3,316E-03 0,08767878 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 3,316E-03 0,08672575 ! micturition GO:0060073 9 5 0,000 3,316E-03 0,08579322 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 3,316E-03 0,08488052 ! copulation GO:0007620 9 5 0,000 3,316E-03 0,08398705 ! glial cell fate commitment GO:0021781 13 5 0,000 3,316E-03 0,08311218 ! protein maturation by protein folding GO:0022417 13 5 0,000 3,316E-03 0,08225535 ! spermidine metabolic process GO:0008216 7 5 0,000 3,316E-03 0,08141601 ! regulation of potassium ion transport GO:0043266 10 5 0,000 3,316E-03 0,08059363 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 3,316E-03 0,07978769 ! apoptotic cell clearance GO:0043277 20 5 0,000 3,316E-03 0,07899772 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 3,316E-03 0,07822323 ! lipoprotein particle clearance GO:0034381 10 5 0,000 3,316E-03 0,07746378 ! grooming behavior GO:0007625 6 5 0,000 3,316E-03 0,07671894 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 3,316E-03 0,07598828 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 3,316E-03 0,07527141 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 3,316E-03 0,07456794 ! response to protozoan GO:0001562 10 5 0,000 3,316E-03 0,07387749 ! positive regulation of glycolysis GO:0045821 14 5 0,000 3,316E-03 0,07319972 ! lymph vessel development GO:0001945 10 5 0,000 3,316E-03 0,07253427 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 3,316E-03 0,0718808 ! endochondral ossification GO:0001958 16 5 0,000 3,316E-03 0,07123901 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 3,316E-03 0,07060858 ! parathyroid gland development GO:0060017 13 5 0,000 3,316E-03 0,0699892 ! anagen GO:0042640 6 5 0,000 3,316E-03 0,0693806 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 3,316E-03 0,06878249 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 3,316E-03 0,06819461 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 3,316E-03 0,06761669 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 3,316E-03 0,06704848 ! dorsal spinal cord development GO:0021516 7 5 0,000 3,316E-03 0,06648974 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 3,316E-03 0,06594024 ! sphingoid catabolic process GO:0046521 6 5 0,000 3,316E-03 0,06539975 ! skeletal myofibril assembly GO:0014866 10 5 0,000 3,316E-03 0,06486804 ! smooth muscle tissue development GO:0048745 28 5 0,000 3,316E-03 0,06434491 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 3,316E-03 0,06383015 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 3,316E-03 0,06332357 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 3,316E-03 0,06282496 ! cardiac muscle fiber development GO:0048739 10 5 0,000 3,316E-03 0,06233414 ! transepithelial chloride transport GO:0030321 9 5 0,000 3,316E-03 0,06185092 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 3,316E-03 0,06137515 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 3,316E-03 0,06090664 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 3,316E-03 0,06044522 ! neutrophil mediated immunity GO:0002446 7 5 0,000 3,316E-03 0,05999075 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 3,316E-03 0,05954305 ! histidine catabolic process GO:0006548 6 5 0,000 3,316E-03 0,05910199 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 3,316E-03 0,05866742 ! microvillus organization GO:0032528 7 5 0,000 3,316E-03 0,05823919 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 3,316E-03 0,05781717 ! L-serine biosynthetic process GO:0006564 6 5 0,000 3,316E-03 0,05740122 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 3,316E-03 0,05699121 ! tryptophan metabolic process GO:0006568 9 5 0,000 3,316E-03 0,05658702 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 3,316E-03 0,05618852 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 3,316E-03 0,05579559 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 3,316E-03 0,05540812 ! polyol biosynthetic process GO:0046173 5 5 0,000 3,316E-03 0,055026 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 3,316E-03 0,0546491 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 3,316E-03 0,05427734 ! muscle cell migration GO:0014812 8 5 0,000 3,316E-03 0,0539106 ! mitochondrial fission GO:0000266 8 5 0,000 3,316E-03 0,05354879 ! sister chromatid cohesion GO:0007062 12 5 0,000 3,316E-03 0,0531918 ! mRNA transcription GO:0009299 9 5 0,000 3,316E-03 0,05283953 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 3,316E-03 0,0524919 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 3,316E-03 0,05214882 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 3,316E-03 0,05181019 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 3,316E-03 0,05147593 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 3,316E-03 0,05114596 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 3,316E-03 0,05082019 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 3,316E-03 0,05049854 ! response to food GO:0032094 6 5 0,000 3,316E-03 0,05018094 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 3,316E-03 0,04986731 ! positive regulation of transporter activity GO:0032411 8 5 0,000 3,316E-03 0,04955757 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 3,316E-03 0,04925166 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 3,316E-03 0,0489495 ! paraxial mesoderm development GO:0048339 14 5 0,000 3,316E-03 0,04865103 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 3,316E-03 0,04835618 ! forebrain neuron development GO:0021884 13 5 0,000 3,316E-03 0,04806488 ! lipoprotein catabolic process GO:0042159 11 5 0,000 3,316E-03 0,04777706 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 3,316E-03 0,04749267 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 3,316E-03 0,04721165 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 3,316E-03 0,04693394 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 3,316E-03 0,04665947 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 3,316E-03 0,04638819 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 3,316E-03 0,04612005 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 3,316E-03 0,045855 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 3,316E-03 0,04559297 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 3,316E-03 0,04533392 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 3,316E-03 0,04507779 ! basic amino acid transport GO:0015802 11 5 0,000 3,316E-03 0,04482455 ! cellular glucose homeostasis GO:0001678 5 5 0,000 3,316E-03 0,04457413 ! early endosome to late endosome transport GO:0045022 12 5 0,000 3,316E-03 0,0443265 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 3,316E-03 0,0440816 ! depyrimidination GO:0045008 10 5 0,000 3,316E-03 0,04383939 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 3,316E-03 0,04359983 ! regulation of centrosome cycle GO:0046605 7 5 0,000 3,316E-03 0,04336288 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 3,316E-03 0,04312848 ! zinc ion homeostasis GO:0055069 8 5 0,000 3,316E-03 0,04289661 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 3,316E-03 0,04266722 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 3,316E-03 0,04244026 ! forebrain morphogenesis GO:0048853 13 5 0,000 3,316E-03 0,04221571 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 3,316E-03 0,04199352 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 3,316E-03 0,04177366 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 3,316E-03 0,04155609 ! peptidyl-arginine modification GO:0018195 9 5 0,000 3,316E-03 0,04134077 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 3,316E-03 0,04112768 ! positive regulation of organ growth GO:0046622 6 5 0,000 3,316E-03 0,04091677 ! response to arsenic GO:0046685 10 5 0,000 3,316E-03 0,04070801 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 3,316E-03 0,04050137 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 3,316E-03 0,04029681 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 3,316E-03 0,04009432 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 3,316E-03 0,03989385 ! response to cadmium ion GO:0046686 7 5 0,000 3,316E-03 0,03969537 ! bile acid biosynthetic process GO:0006699 6 5 0,000 3,316E-03 0,03949886 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 3,316E-03 0,03930428 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 3,316E-03 0,03911161 ! decidualization GO:0046697 11 5 0,000 3,316E-03 0,03892083 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 3,316E-03 0,03873189 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 3,316E-03 0,03854478 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 3,316E-03 0,03835947 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 3,316E-03 0,03817593 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 3,316E-03 0,03799414 ! base conversion or substitution editing GO:0016553 5 5 0,000 3,316E-03 0,03781407 ! neural tube patterning GO:0021532 7 5 0,000 3,316E-03 0,0376357 ! embryonic cleavage GO:0040016 6 5 0,000 3,316E-03 0,03745901 ! peroxisome fission GO:0016559 5 5 0,000 3,316E-03 0,03728397 ! histone demethylation GO:0016577 10 5 0,000 3,316E-03 0,03711055 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 3,316E-03 0,03693875 ! mitotic recombination GO:0006312 9 5 0,000 3,316E-03 0,03676852 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 3,316E-03 0,03659986 ! metaphase plate congression GO:0051310 7 5 0,000 3,316E-03 0,03643274 ! regulation of sterol transport GO:0032371 7 5 0,000 3,316E-03 0,03626713 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 3,316E-03 0,03610303 ! enteric nervous system development GO:0048484 8 5 0,000 3,316E-03 0,0359404 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 3,316E-03 0,03577923 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 3,316E-03 0,03561951 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 3,316E-03 0,0354612 ! muscle cell proliferation GO:0033002 11 5 0,000 3,316E-03 0,03530429 ! skeletal muscle regeneration GO:0043403 8 5 0,000 3,316E-03 0,03514876 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 3,316E-03 0,0349946 ! plasminogen activation GO:0031639 5 5 0,000 3,316E-03 0,03484179 ! B cell homeostasis GO:0001782 13 5 0,000 3,316E-03 0,0346903 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 3,316E-03 0,03454013 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 3,316E-03 0,03439125 ! metaphase GO:0051323 8 5 0,000 3,316E-03 0,03424365 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 3,316E-03 0,0340973 ! cellular response to nutrient GO:0031670 8 5 0,000 3,316E-03 0,03395221 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 3,316E-03 0,03380834 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 3,316E-03 0,03366569 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 3,316E-03 0,03352424 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 3,316E-03 0,03338397 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 3,316E-03 0,03324487 ! response to redox state GO:0051775 5 5 0,000 3,316E-03 0,03310693 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 3,316E-03 0,03297012 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 3,316E-03 0,03283444 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 3,316E-03 0,03269987 ! regulation of telomerase activity GO:0051972 6 5 0,000 3,316E-03 0,03256641 ! galactolipid metabolic process GO:0019374 7 5 0,000 3,316E-03 0,03243402 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 3,316E-03 0,03230271 ! porphyrin catabolic process GO:0006787 12 5 0,000 3,316E-03 0,03217246 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 3,316E-03 0,03204325 ! striatum development GO:0021756 9 5 0,000 3,316E-03 0,03191508 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 3,316E-03 0,03178793 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 3,316E-03 0,03166178 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 3,316E-03 0,03153664 ! glial cell migration GO:0008347 11 5 0,000 3,316E-03 0,03141248 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 3,316E-03 0,03128929 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 3,316E-03 0,03116707 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 3,316E-03 0,03104579 ! somatic stem cell maintenance GO:0035019 15 5 0,000 3,316E-03 0,03092546 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 3,316E-03 0,03080606 ! negative regulation of lipase activity GO:0060192 8 5 0,000 3,316E-03 0,03068757 ! neuroprotection GO:0043526 6 5 0,000 3,316E-03 0,03057 ! neural plate development GO:0001840 8 5 0,000 3,316E-03 0,03045332 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 3,316E-03 0,03033753 ! regulation of sensory perception GO:0051931 7 5 0,000 3,316E-03 0,03022261 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 3,316E-03 0,03010856 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 3,316E-03 0,02999537 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 3,316E-03 0,02988303 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 3,316E-03 0,02977153 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 3,316E-03 0,02966085 ! sequestering of calcium ion GO:0051208 7 5 0,000 3,316E-03 0,029551 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 3,316E-03 0,02944195 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 3,316E-03 0,02933371 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 3,316E-03 0,02922626 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 3,316E-03 0,0291196 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 3,316E-03 0,02901371 ! drug metabolic process GO:0017144 6 5 0,000 3,316E-03 0,02890858 ! stem cell division GO:0017145 11 5 0,000 3,316E-03 0,02880422 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 3,316E-03 0,02870061 ! organ regeneration GO:0031100 7 5 0,000 3,316E-03 0,02859774 ! carnitine metabolic process GO:0009437 7 5 0,000 3,316E-03 0,0284956 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 3,316E-03 0,0283942 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 3,316E-03 0,02829351 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 3,978E-03 0,03382157 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 3,978E-03 0,03370248 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 3,978E-03 0,03358422 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 3,978E-03 0,0334668 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 3,978E-03 0,03335019 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 3,978E-03 0,03323439 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 3,978E-03 0,03311939 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 3,978E-03 0,03300519 ! sleep GO:0030431 13 6 0,000 3,978E-03 0,03289177 ! response to oxygen radical GO:0000305 11 6 0,000 3,978E-03 0,03277912 ! positive regulation of axon extension GO:0045773 11 6 0,000 3,978E-03 0,03266725 ! myoblast cell fate commitment GO:0048625 16 6 0,000 3,978E-03 0,03255614 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 3,978E-03 0,03244578 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 3,978E-03 0,03233616 ! regulation of interferon-beta production GO:0032648 8 6 0,000 3,978E-03 0,03222729 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 3,978E-03 0,03211914 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 3,978E-03 0,03201172 ! forebrain regionalization GO:0021871 8 6 0,000 3,978E-03 0,03190501 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 3,978E-03 0,03179902 ! male meiosis GO:0007140 7 6 0,000 3,978E-03 0,03169372 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 3,978E-03 0,03158912 ! response to zinc ion GO:0010043 9 6 0,000 3,978E-03 0,03148521 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 3,978E-03 0,03138198 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 3,978E-03 0,03127942 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 3,978E-03 0,03117754 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 3,978E-03 0,03107631 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 3,978E-03 0,03097574 ! malate metabolic process GO:0006108 11 6 0,000 3,978E-03 0,03087582 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 3,978E-03 0,03077654 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 3,978E-03 0,0306779 ! protein refolding GO:0042026 15 6 0,000 3,978E-03 0,03057988 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 3,978E-03 0,0304825 ! opsonization GO:0008228 8 6 0,000 3,978E-03 0,03038573 ! mating behavior GO:0007617 7 6 0,000 3,978E-03 0,03028957 ! neuron remodeling GO:0016322 15 6 0,000 3,978E-03 0,03019402 ! erythrocyte maturation GO:0043249 7 6 0,000 3,978E-03 0,03009907 ! embryonic hemopoiesis GO:0035162 14 6 0,000 3,978E-03 0,03000471 ! equilibrioception GO:0050957 14 6 0,000 3,978E-03 0,02991095 ! protein amino acid dealkylation GO:0008214 12 6 0,000 3,978E-03 0,02981777 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 3,978E-03 0,02972517 ! photoreceptor cell development GO:0042461 10 6 0,000 3,978E-03 0,02963314 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 3,978E-03 0,02954168 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 3,978E-03 0,02945078 ! response to interferon-gamma GO:0034341 15 6 0,000 3,978E-03 0,02936044 ! toxin metabolic process GO:0009404 11 6 0,000 3,978E-03 0,02927065 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 3,978E-03 0,02918141 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 3,978E-03 0,02909272 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 3,978E-03 0,02900456 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 3,978E-03 0,02891693 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 3,978E-03 0,02882983 ! cGMP-mediated signaling GO:0019934 13 6 0,000 3,978E-03 0,02874326 ! activation of MAPKKK activity GO:0000185 12 6 0,000 3,978E-03 0,0286572 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 3,978E-03 0,02857165 ! thymic T cell selection GO:0045061 12 6 0,000 3,978E-03 0,02848662 ! protein lipoylation GO:0009249 10 6 0,000 3,978E-03 0,02840209 ! cysteine metabolic process GO:0006534 10 6 0,000 3,978E-03 0,02831806 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 3,978E-03 0,02823452 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 3,978E-03 0,02815148 ! glutamate catabolic process GO:0006538 10 6 0,000 3,978E-03 0,02806893 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 3,978E-03 0,02798685 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 3,978E-03 0,02790526 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 3,978E-03 0,02782414 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 3,978E-03 0,02774349 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 3,978E-03 0,02766331 ! hyperosmotic response GO:0006972 9 6 0,000 3,978E-03 0,02758358 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 3,978E-03 0,02750432 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 3,978E-03 0,02742551 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 3,978E-03 0,02734715 ! urea metabolic process GO:0019627 7 6 0,000 3,978E-03 0,02726924 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 3,978E-03 0,02719177 ! neutrophil activation GO:0042119 8 6 0,000 3,978E-03 0,02711474 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 3,978E-03 0,02703815 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 3,978E-03 0,02696198 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 3,978E-03 0,02688625 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 3,978E-03 0,02681094 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 3,978E-03 0,02673604 ! neuron apoptosis GO:0051402 9 6 0,000 3,978E-03 0,02666157 ! nucleoside salvage GO:0043174 9 6 0,000 3,978E-03 0,02658751 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 3,978E-03 0,02651386 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 3,978E-03 0,02644062 ! T cell mediated immunity GO:0002456 16 6 0,000 3,978E-03 0,02636778 ! negative regulation of platelet activation GO:0010544 9 6 0,000 3,978E-03 0,02629534 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 3,978E-03 0,0262233 ! carnitine transport GO:0015879 10 6 0,000 3,978E-03 0,02615165 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 3,978E-03 0,02608039 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 3,978E-03 0,02600952 ! positive regulation of exocytosis GO:0045921 8 6 0,000 3,978E-03 0,02593904 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 3,978E-03 0,02586893 ! 5S class rRNA transcription GO:0042791 11 6 0,000 3,978E-03 0,0257992 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 3,978E-03 0,02572985 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 3,978E-03 0,02566087 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 3,978E-03 0,02559226 ! sodium ion homeostasis GO:0055078 11 6 0,000 3,978E-03 0,02552401 ! establishment of spindle localization GO:0051293 12 6 0,000 3,978E-03 0,02545613 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 3,978E-03 0,0253886 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 3,978E-03 0,02532144 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 3,978E-03 0,02525463 ! neural nucleus development GO:0048857 14 6 0,000 3,978E-03 0,02518817 ! response to UV-C GO:0010225 11 6 0,000 3,978E-03 0,02512206 ! astrocyte development GO:0014002 15 6 0,000 3,978E-03 0,02505629 ! protein targeting to lysosome GO:0006622 10 6 0,000 3,978E-03 0,02499087 ! purine base biosynthetic process GO:0009113 17 6 0,000 3,978E-03 0,02492579 ! interaction with symbiont GO:0051702 13 6 0,000 3,978E-03 0,02486105 ! regulation of dendrite development GO:0050773 16 6 0,000 3,978E-03 0,02479664 ! skeletal muscle contraction GO:0003009 6 6 0,000 3,978E-03 0,02473257 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 3,978E-03 0,02466882 ! response to copper ion GO:0046688 10 6 0,000 3,978E-03 0,02460541 ! response to exogenous dsRNA GO:0043330 10 6 0,000 3,978E-03 0,02454232 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 3,978E-03 0,02447955 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 3,978E-03 0,0244171 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 3,978E-03 0,02435497 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 3,978E-03 0,02429316 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 3,978E-03 0,02423166 ! regulation of dopamine secretion GO:0014059 14 6 0,000 3,978E-03 0,02417046 ! nucleoside catabolic process GO:0009164 7 6 0,000 3,978E-03 0,02410958 ! hair follicle maturation GO:0048820 7 6 0,000 3,978E-03 0,024049 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 3,978E-03 0,02398873 ! Schwann cell development GO:0014044 15 6 0,000 3,978E-03 0,02392876 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 3,978E-03 0,02386909 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 3,978E-03 0,02380971 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 3,978E-03 0,02375063 ! subpallium development GO:0021544 10 6 0,000 3,978E-03 0,02369184 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 3,978E-03 0,02363334 ! histone ubiquitination GO:0016574 8 6 0,000 3,978E-03 0,02357513 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 3,978E-03 0,02351721 ! maintenance of organ identity GO:0048496 9 6 0,000 3,978E-03 0,02345957 ! G2 phase GO:0051319 16 6 0,000 3,978E-03 0,02340221 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 3,978E-03 0,02334513 ! establishment of planar polarity GO:0001736 7 6 0,000 3,978E-03 0,02328833 ! regulation of mast cell activation GO:0033003 12 6 0,000 3,978E-03 0,02323181 ! membrane to membrane docking GO:0022614 14 6 0,000 3,978E-03 0,02317555 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 3,978E-03 0,02311957 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 3,978E-03 0,02306386 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 3,978E-03 0,02300842 ! receptor internalization GO:0031623 10 6 0,000 3,978E-03 0,02295325 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 3,978E-03 0,02289833 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 3,978E-03 0,02284368 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 3,978E-03 0,0227893 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 3,978E-03 0,02273516 ! protein deubiquitination GO:0016579 14 6 0,000 3,978E-03 0,02268129 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 3,978E-03 0,02262767 ! protein destabilization GO:0031648 9 6 0,000 3,978E-03 0,0225743 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 3,978E-03 0,02252119 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 3,978E-03 0,02246832 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 3,978E-03 0,0224157 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 3,978E-03 0,02236333 ! progesterone metabolic process GO:0042448 10 6 0,000 3,978E-03 0,0223112 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 3,978E-03 0,02225931 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 3,978E-03 0,02220767 ! negative regulation of axon extension GO:0030517 21 6 0,000 3,978E-03 0,02215626 ! removal of superoxide radicals GO:0019430 11 6 0,000 3,978E-03 0,02210509 ! triglyceride catabolic process GO:0019433 10 6 0,000 3,978E-03 0,02205416 ! determination of adult lifespan GO:0008340 15 6 0,000 3,978E-03 0,02200346 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 3,978E-03 0,02195299 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 3,978E-03 0,02190275 ! cerebellar cortex formation GO:0021697 8 6 0,000 3,978E-03 0,02185275 ! catecholamine transport GO:0051937 9 6 0,000 3,978E-03 0,02180297 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 3,978E-03 0,02175342 ! sensory cilium assembly GO:0035058 10 6 0,000 3,978E-03 0,02170409 ! organ or tissue specific immune response GO:0002251 7 6 0,000 3,978E-03 0,02165499 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 3,978E-03 0,0216061 ! maternal placenta development GO:0001893 12 6 0,000 3,978E-03 0,02155744 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 3,978E-03 0,021509 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 3,978E-03 0,02146077 ! negative regulation of B cell activation GO:0050869 13 6 0,000 3,978E-03 0,02141276 ! protein amino acid prenylation GO:0018346 16 6 0,000 3,978E-03 0,02136496 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 3,978E-03 0,02131738 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 3,978E-03 0,02127001 ! positive regulation of coagulation GO:0050820 12 6 0,000 3,978E-03 0,02122285 ! tRNA transcription GO:0009304 14 7 0,000 4,64E-03 0,02469742 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 4,64E-03 0,0246429 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 4,64E-03 0,02458862 ! behavioral response to cocaine GO:0048148 14 7 0,000 4,64E-03 0,02453458 ! regulation of helicase activity GO:0051095 15 7 0,000 4,64E-03 0,02448078 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 4,64E-03 0,02442721 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 4,64E-03 0,02437387 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 4,64E-03 0,02432077 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 4,64E-03 0,0242679 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 4,64E-03 0,02421526 ! prostate gland development GO:0030850 13 7 0,000 4,64E-03 0,02416284 ! nucleotide-sugar transport GO:0015780 12 7 0,000 4,64E-03 0,02411066 ! synaptonemal complex assembly GO:0007130 10 7 0,000 4,64E-03 0,02405869 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 4,64E-03 0,02400695 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 4,64E-03 0,02395544 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 4,64E-03 0,02390414 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 4,64E-03 0,02385306 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 4,64E-03 0,0238022 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 4,64E-03 0,02375156 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 4,64E-03 0,02370113 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 4,64E-03 0,02365092 ! SMAD protein complex assembly GO:0007183 12 7 0,000 4,64E-03 0,02360092 ! glycolipid transport GO:0046836 10 7 0,000 4,64E-03 0,02355113 ! protein amino acid sulfation GO:0006477 10 7 0,000 4,64E-03 0,02350154 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 4,64E-03 0,02345217 ! neuron adhesion GO:0007158 12 7 0,000 4,64E-03 0,02340301 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 4,64E-03 0,02335405 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 4,64E-03 0,02330529 ! actin-myosin filament sliding GO:0033275 11 7 0,000 4,64E-03 0,02325674 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 4,64E-03 0,02320839 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 4,64E-03 0,02316024 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 4,64E-03 0,02311228 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 4,64E-03 0,02306453 ! mRNA stabilization GO:0048255 18 7 0,000 4,64E-03 0,02301698 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 4,64E-03 0,02296962 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 4,64E-03 0,02292245 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 4,64E-03 0,02287548 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 4,64E-03 0,0228287 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 4,64E-03 0,02278211 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 4,64E-03 0,02273571 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 4,64E-03 0,0226895 ! lipoprotein transport GO:0042953 14 7 0,000 4,64E-03 0,02264348 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 4,64E-03 0,02259764 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 4,64E-03 0,02255199 ! rhythmic behavior GO:0007622 15 7 0,000 4,64E-03 0,02250652 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 4,64E-03 0,02246123 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 4,64E-03 0,02241613 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 4,64E-03 0,02237121 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 4,64E-03 0,02232647 ! regulation of odontogenesis GO:0042481 13 7 0,000 4,64E-03 0,0222819 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 4,64E-03 0,02223752 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 4,64E-03 0,02219331 ! mechanosensory behavior GO:0007638 14 7 0,000 4,64E-03 0,02214927 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 4,64E-03 0,02210541 ! positive regulation of isotype switching GO:0045830 15 7 0,000 4,64E-03 0,02206173 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 4,64E-03 0,02201821 ! protein-cofactor linkage GO:0018065 13 7 0,000 4,64E-03 0,02197487 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 4,64E-03 0,0219317 ! spinal cord patterning GO:0021511 13 7 0,000 4,64E-03 0,02188869 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 4,64E-03 0,02184586 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 4,64E-03 0,02180319 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 4,64E-03 0,02176069 ! adrenal gland development GO:0030325 17 7 0,000 4,64E-03 0,02171835 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 4,64E-03 0,02167618 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 4,64E-03 0,02163417 ! ovulation GO:0030728 9 7 0,000 4,64E-03 0,02159233 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 4,64E-03 0,02155064 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 4,64E-03 0,02150912 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 4,64E-03 0,02146776 ! microtubule nucleation GO:0007020 20 7 0,000 4,64E-03 0,02142655 ! proline biosynthetic process GO:0006561 10 7 0,000 4,64E-03 0,0213855 ! thyroid hormone generation GO:0006590 13 7 0,000 4,64E-03 0,02134461 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 4,64E-03 0,02130388 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 4,64E-03 0,0212633 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 4,64E-03 0,02122288 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 4,64E-03 0,02118261 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 4,64E-03 0,02114249 ! galactose metabolic process GO:0006012 13 7 0,000 4,64E-03 0,02110252 ! vesicle fusion GO:0006906 17 7 0,000 4,64E-03 0,0210627 ! response to dietary excess GO:0002021 8 7 0,000 4,64E-03 0,02102304 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 4,64E-03 0,02098352 ! intracellular pH reduction GO:0051452 11 7 0,000 4,64E-03 0,02094415 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 4,64E-03 0,02090493 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 4,64E-03 0,02086586 ! organ growth GO:0035265 15 7 0,000 4,64E-03 0,02082693 ! purine salvage GO:0043101 10 7 0,000 4,64E-03 0,02078814 ! nucleoside transport GO:0015858 8 7 0,000 4,64E-03 0,0207495 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 4,64E-03 0,02071101 ! parturition GO:0007567 14 7 0,000 4,64E-03 0,02067265 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 4,64E-03 0,02063444 ! rRNA modification GO:0000154 14 7 0,000 4,64E-03 0,02059637 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 4,64E-03 0,02055844 ! spindle checkpoint GO:0031577 15 7 0,000 4,64E-03 0,02052065 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 4,64E-03 0,020483 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 4,64E-03 0,02044548 ! macrophage differentiation GO:0030225 11 7 0,000 4,64E-03 0,02040811 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 4,64E-03 0,02037086 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 4,64E-03 0,02033376 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 4,64E-03 0,02029679 ! hyaluronan metabolic process GO:0030212 8 7 0,000 4,64E-03 0,02025995 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 4,64E-03 0,02022325 ! anterograde axon cargo transport GO:0008089 18 7 0,000 4,64E-03 0,02018668 ! fibrinolysis GO:0042730 10 7 0,000 4,64E-03 0,02015024 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 4,64E-03 0,02011393 ! eating behavior GO:0042755 7 7 0,000 4,64E-03 0,02007776 ! B cell lineage commitment GO:0002326 21 7 0,000 4,64E-03 0,02004171 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 4,64E-03 0,02000579 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 4,64E-03 0,01997001 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 4,64E-03 0,01993435 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 4,64E-03 0,01989881 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 4,64E-03 0,0198634 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 4,64E-03 0,01982812 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 4,64E-03 0,01979297 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 4,64E-03 0,01975794 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 4,64E-03 0,01972303 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 4,64E-03 0,01968824 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 4,64E-03 0,01965358 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 4,64E-03 0,01961904 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 4,64E-03 0,01958462 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 4,64E-03 0,01955032 ! regulation of meiosis GO:0040020 12 7 0,000 4,64E-03 0,01951614 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 4,64E-03 0,01948208 ! T cell lineage commitment GO:0002360 16 7 0,000 4,64E-03 0,01944814 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 4,64E-03 0,01941432 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 4,64E-03 0,01938061 ! oxygen homeostasis GO:0032364 12 7 0,000 4,64E-03 0,01934703 ! transcription termination GO:0006353 13 7 0,000 4,64E-03 0,01931355 ! response to tumor cell GO:0002347 13 7 0,000 4,64E-03 0,0192802 ! regulation of respiratory burst GO:0060263 11 7 0,000 4,64E-03 0,01924695 ! coenzyme A metabolic process GO:0015936 12 7 0,000 4,64E-03 0,01921383 ! anaphase GO:0051322 17 7 0,000 4,64E-03 0,01918081 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 4,64E-03 0,01914791 ! axonal fasciculation GO:0007413 18 7 0,000 4,64E-03 0,01911513 ! negative regulation of nuclear division GO:0051784 14 7 0,000 4,64E-03 0,01908245 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 4,64E-03 0,01904989 ! peptidyl-threonine modification GO:0018210 25 7 0,000 4,64E-03 0,01901743 ! diuresis GO:0030146 12 7 0,000 4,64E-03 0,01898509 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 4,64E-03 0,01895286 ! thiamin metabolic process GO:0006772 7 7 0,000 4,64E-03 0,01892073 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 4,64E-03 0,01888872 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 4,64E-03 0,01885681 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 4,64E-03 0,01882501 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 4,64E-03 0,01879332 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 4,64E-03 0,01876174 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 4,64E-03 0,01873026 ! melanin biosynthetic process GO:0042438 8 7 0,000 4,64E-03 0,01869888 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 4,64E-03 0,01866761 ! dopamine biosynthetic process GO:0042416 18 7 0,000 4,64E-03 0,01863645 ! glycolipid catabolic process GO:0019377 15 7 0,000 4,64E-03 0,01860539 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 4,64E-03 0,01857443 ! lymph node development GO:0048535 10 7 0,000 4,64E-03 0,01854358 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 4,64E-03 0,01851283 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 4,64E-03 0,01848217 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 4,64E-03 0,01845163 ! endosome to lysosome transport GO:0008333 11 7 0,000 4,64E-03 0,01842118 ! protein modification by small protein removal GO:0070646 16 7 0,000 4,64E-03 0,01839083 ! adult feeding behavior GO:0008343 9 7 0,000 4,64E-03 0,01836058 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 4,64E-03 0,01833043 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 4,64E-03 0,01830038 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 4,64E-03 0,01827043 ! muscle adaptation GO:0043500 14 7 0,000 4,64E-03 0,01824058 ! embryonic heart tube development GO:0035050 10 7 0,000 4,64E-03 0,01821082 ! retina homeostasis GO:0001895 12 7 0,000 4,64E-03 0,01818116 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 4,64E-03 0,0181516 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 4,64E-03 0,01812213 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 4,64E-03 0,01809276 ! protein prenylation GO:0018342 18 7 0,000 4,64E-03 0,01806348 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 4,64E-03 0,0180343 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 4,64E-03 0,01800522 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 4,64E-03 0,01797622 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 5,301E-03 0,02050476 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 5,301E-03 0,02047184 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 5,301E-03 0,02043904 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 5,301E-03 0,02040633 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 5,301E-03 0,02037374 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 5,301E-03 0,02034124 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 5,301E-03 0,02030885 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 5,301E-03 0,02027656 ! neutral lipid catabolic process GO:0046461 13 8 0,000 5,301E-03 0,02024438 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 5,301E-03 0,0202123 ! meiotic prophase I GO:0007128 13 8 0,000 5,301E-03 0,02018031 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 5,301E-03 0,02014843 ! oligopeptide transport GO:0006857 15 8 0,000 5,301E-03 0,02011665 ! UTP metabolic process GO:0046051 8 8 0,000 5,301E-03 0,02008497 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 5,301E-03 0,02005339 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 5,301E-03 0,02002191 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 5,301E-03 0,01999053 ! macrophage chemotaxis GO:0048246 12 8 0,000 5,301E-03 0,01995925 ! succinate metabolic process GO:0006105 14 8 0,000 5,301E-03 0,01992806 ! membrane hyperpolarization GO:0060081 10 8 0,000 5,301E-03 0,01989697 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 5,301E-03 0,01986598 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 5,301E-03 0,01983508 ! T-helper 1 type immune response GO:0042088 12 8 0,000 5,301E-03 0,01980428 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 5,301E-03 0,01977358 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 5,301E-03 0,01974297 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 5,301E-03 0,01971246 ! ganglioside metabolic process GO:0001573 19 8 0,000 5,301E-03 0,01968204 ! reflex GO:0060004 16 8 0,000 5,301E-03 0,01965171 ! negative regulation of endocytosis GO:0045806 11 8 0,000 5,301E-03 0,01962147 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 5,301E-03 0,01959133 ! endothelial cell differentiation GO:0045446 17 8 0,000 5,301E-03 0,01956129 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 5,301E-03 0,01953133 ! glycerolipid catabolic process GO:0046503 13 8 0,000 5,301E-03 0,01950147 ! hemoglobin metabolic process GO:0020027 13 8 0,000 5,301E-03 0,01947169 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 5,301E-03 0,01944201 ! pigment granule organization GO:0048753 16 8 0,000 5,301E-03 0,01941242 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 5,301E-03 0,01938292 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 5,301E-03 0,0193535 ! astrocyte differentiation GO:0048708 18 8 0,000 5,301E-03 0,01932418 ! histidine metabolic process GO:0006547 16 8 0,000 5,301E-03 0,01929495 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 5,301E-03 0,0192658 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 5,301E-03 0,01923674 ! glycine catabolic process GO:0006546 13 8 0,000 5,301E-03 0,01920777 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 5,301E-03 0,01917889 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 5,301E-03 0,01915009 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 5,301E-03 0,01912138 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 5,301E-03 0,01909275 ! regulation of pigmentation during development GO:0048070 24 8 0,000 5,301E-03 0,01906421 ! melanin metabolic process GO:0006582 15 8 0,000 5,301E-03 0,01903576 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 5,301E-03 0,01900739 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 5,301E-03 0,01897911 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 5,301E-03 0,0189509 ! macrophage activation GO:0042116 12 8 0,000 5,301E-03 0,01892279 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 5,301E-03 0,01889475 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 5,301E-03 0,0188668 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 5,301E-03 0,01883893 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 5,301E-03 0,01881115 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 5,301E-03 0,01878344 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 5,301E-03 0,01875582 ! regulation of vascular permeability GO:0043114 12 8 0,000 5,301E-03 0,01872828 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 5,301E-03 0,01870082 ! osteoblast development GO:0002076 16 8 0,000 5,301E-03 0,01867344 ! positive regulation of vasodilation GO:0045909 13 8 0,000 5,301E-03 0,01864614 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 5,301E-03 0,01861892 ! negative regulation of translational initiation GO:0045947 10 8 0,000 5,301E-03 0,01859178 ! Schwann cell differentiation GO:0014037 19 8 0,000 5,301E-03 0,01856471 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 5,301E-03 0,01853773 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 5,301E-03 0,01851083 ! response to UV-B GO:0010224 16 8 0,000 5,301E-03 0,018484 ! protein targeting to vacuole GO:0006623 12 8 0,000 5,301E-03 0,01845725 ! protein retention in ER lumen GO:0006621 14 8 0,000 5,301E-03 0,01843058 ! intermediate filament organization GO:0045109 12 8 0,000 5,301E-03 0,01840398 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 5,301E-03 0,01837746 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 5,301E-03 0,01835102 ! cellular extravasation GO:0045123 12 8 0,000 5,301E-03 0,01832465 ! cardiac muscle cell development GO:0055013 13 8 0,000 5,301E-03 0,01829836 ! regulation of circadian rhythm GO:0042752 16 8 0,000 5,301E-03 0,01827215 ! response to antibiotic GO:0046677 11 8 0,000 5,301E-03 0,01824601 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 5,301E-03 0,01821994 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 5,301E-03 0,01819395 ! DNA topological change GO:0006265 12 8 0,000 5,301E-03 0,01816803 ! response to tropane GO:0014073 15 8 0,000 5,301E-03 0,01814219 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 5,301E-03 0,01811642 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 5,301E-03 0,01809072 ! melanosome transport GO:0032402 13 8 0,000 5,301E-03 0,0180651 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 0,000 5,301E-03 0,01803955 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 5,301E-03 0,01801407 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 5,301E-03 0,01798866 ! mast cell activation GO:0045576 14 8 0,000 5,301E-03 0,01796332 ! multicellular organismal aging GO:0010259 18 8 0,000 5,301E-03 0,01793806 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 5,301E-03 0,01791286 ! dendrite morphogenesis GO:0048813 13 8 0,000 5,301E-03 0,01788774 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 5,301E-03 0,01786269 ! nucleosome disassembly GO:0006337 14 8 0,000 5,301E-03 0,0178377 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 5,301E-03 0,01781279 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 5,301E-03 0,01778795 ! leukocyte activation during immune response GO:0002366 13 8 0,000 5,301E-03 0,01776317 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 5,301E-03 0,01773847 ! establishment of chromosome localization GO:0051303 12 8 0,000 5,301E-03 0,01771383 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 5,301E-03 0,01768926 ! intracellular lipid transport GO:0032365 13 8 0,000 5,301E-03 0,01766476 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 5,301E-03 0,01764033 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 5,301E-03 0,01761597 ! regulation of macrophage activation GO:0043030 15 8 0,000 5,301E-03 0,01759167 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 5,301E-03 0,01756744 ! positive regulation of epidermis development GO:0045684 13 8 0,000 5,301E-03 0,01754327 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 5,301E-03 0,01751917 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 5,301E-03 0,01749514 ! hormone catabolic process GO:0042447 17 8 0,000 5,301E-03 0,01747118 ! positive regulation of glucose import GO:0046326 8 8 0,000 5,301E-03 0,01744728 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 5,301E-03 0,01742344 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 5,301E-03 0,01739967 ! ATP catabolic process GO:0006200 11 8 0,000 5,301E-03 0,01737597 ! blastocyst growth GO:0001832 19 8 0,000 5,301E-03 0,01735232 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 5,301E-03 0,01732875 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 5,301E-03 0,01730524 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 5,301E-03 0,01728179 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 5,301E-03 0,0172584 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 5,301E-03 0,01723508 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 5,301E-03 0,01721182 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 5,301E-03 0,01718862 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 5,301E-03 0,01716549 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 5,301E-03 0,01714242 ! amino sugar catabolic process GO:0046348 10 8 0,000 5,301E-03 0,01711941 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 5,301E-03 0,01709646 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 5,301E-03 0,01707357 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 5,301E-03 0,01705075 ! behavioral response to nicotine GO:0035095 12 8 0,000 5,301E-03 0,01702798 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 5,301E-03 0,01700528 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 5,301E-03 0,01698263 ! NAD biosynthetic process GO:0009435 13 8 0,000 5,301E-03 0,01696005 ! regulation of developmental growth GO:0048638 15 9 0,000 5,962E-03 0,01904871 ! axon extension GO:0048675 15 9 0,000 5,962E-03 0,01902345 ! autophagic vacuole formation GO:0000045 15 9 0,000 5,962E-03 0,01899825 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 5,962E-03 0,01897312 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 5,962E-03 0,01894806 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 5,962E-03 0,01892306 ! pentose-phosphate shunt GO:0006098 16 9 0,000 5,962E-03 0,01889813 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 5,962E-03 0,01887326 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 5,962E-03 0,01884846 ! cell proliferation in forebrain GO:0021846 15 9 0,000 5,962E-03 0,01882373 ! phosphate transport GO:0006817 19 9 0,000 5,962E-03 0,01879906 ! reproductive behavior GO:0019098 19 9 0,000 5,962E-03 0,01877445 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 5,962E-03 0,01874991 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 5,962E-03 0,01872543 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 5,962E-03 0,01870102 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 5,962E-03 0,01867667 ! GTP metabolic process GO:0046039 9 9 0,000 5,962E-03 0,01865238 ! RNA methylation GO:0001510 15 9 0,000 5,962E-03 0,01862816 ! elastic fiber assembly GO:0048251 15 9 0,000 5,962E-03 0,01860399 ! induction of positive chemotaxis GO:0050930 15 9 0,000 5,962E-03 0,0185799 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 5,962E-03 0,01855586 ! artery development GO:0060840 24 9 0,000 5,962E-03 0,01853189 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 5,962E-03 0,01850797 ! regulation of glycolysis GO:0006110 21 9 0,000 5,962E-03 0,01848412 ! cerebral cortex cell migration GO:0021795 15 9 0,000 5,962E-03 0,01846033 ! keratinocyte proliferation GO:0043616 14 9 0,000 5,962E-03 0,01843661 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 5,962E-03 0,01841294 ! chemosensory behavior GO:0007635 20 9 0,000 5,962E-03 0,01838933 ! microtubule bundle formation GO:0001578 21 9 0,000 5,962E-03 0,01836579 ! middle ear morphogenesis GO:0042474 14 9 0,000 5,962E-03 0,0183423 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 5,962E-03 0,01831888 ! leukocyte degranulation GO:0043299 16 9 0,000 5,962E-03 0,01829551 ! bile acid and bile salt transport GO:0015721 13 9 0,000 5,962E-03 0,0182722 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 5,962E-03 0,01824896 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 5,962E-03 0,01822577 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 5,962E-03 0,01820264 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 5,962E-03 0,01817957 ! protein targeting to ER GO:0045047 22 9 0,000 5,962E-03 0,01815656 ! ceramide biosynthetic process GO:0046513 19 9 0,000 5,962E-03 0,0181336 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 5,962E-03 0,01811071 ! T cell selection GO:0045058 23 9 0,000 5,962E-03 0,01808787 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 5,962E-03 0,01806509 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 5,962E-03 0,01804236 ! phosphagen metabolic process GO:0006599 12 9 0,000 5,962E-03 0,0180197 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 5,962E-03 0,01799709 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 5,962E-03 0,01797454 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 5,962E-03 0,01795204 ! regulation of type I interferon production GO:0032479 12 9 0,000 5,962E-03 0,0179296 ! mannose metabolic process GO:0006013 13 9 0,000 5,962E-03 0,01790722 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 5,962E-03 0,01788489 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 5,962E-03 0,01786262 ! Rac protein signal transduction GO:0016601 17 9 0,000 5,962E-03 0,0178404 ! receptor clustering GO:0043113 18 9 0,000 5,962E-03 0,01781824 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 5,962E-03 0,01779613 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 5,962E-03 0,01777408 ! ruffle organization GO:0031529 15 9 0,000 5,962E-03 0,01775208 ! retinol metabolic process GO:0042572 18 9 0,000 5,962E-03 0,01773014 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 5,962E-03 0,01770825 ! behavioral fear response GO:0001662 22 9 0,000 5,962E-03 0,01768641 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 5,962E-03 0,01766463 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 5,962E-03 0,0176429 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 5,962E-03 0,01762123 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 5,962E-03 0,01759961 ! protein heterooligomerization GO:0051291 16 9 0,000 5,962E-03 0,01757804 ! oligodendrocyte development GO:0014003 10 9 0,000 5,962E-03 0,01755652 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 5,962E-03 0,01753506 ! segment specification GO:0007379 13 9 0,000 5,962E-03 0,01751365 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 5,962E-03 0,01749229 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 5,962E-03 0,01747099 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 5,962E-03 0,01744973 ! response to amine stimulus GO:0014075 13 9 0,000 5,962E-03 0,01742853 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 5,962E-03 0,01740738 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 5,962E-03 0,01738628 ! erythrocyte development GO:0048821 15 9 0,000 5,962E-03 0,01736523 ! gas homeostasis GO:0033483 16 9 0,000 5,962E-03 0,01734423 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 5,962E-03 0,01732329 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 5,962E-03 0,01730239 ! renal water homeostasis GO:0003091 14 9 0,000 5,962E-03 0,01728154 ! postreplication repair GO:0006301 22 9 0,000 5,962E-03 0,01726075 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 5,962E-03 0,01724 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 5,962E-03 0,0172193 ! icosanoid secretion GO:0032309 15 9 0,000 5,962E-03 0,01719866 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 5,962E-03 0,01717806 ! cerebellum morphogenesis GO:0021587 14 9 0,000 5,962E-03 0,01715751 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 5,962E-03 0,01713701 ! regulation of cell division GO:0051302 15 9 0,000 5,962E-03 0,01711656 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 5,962E-03 0,01709616 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 5,962E-03 0,01707581 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 5,962E-03 0,01705551 ! sterol catabolic process GO:0016127 11 9 0,000 5,962E-03 0,01703525 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 5,962E-03 0,01701504 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 5,962E-03 0,01699488 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 5,962E-03 0,01697477 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 5,962E-03 0,0169547 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 5,962E-03 0,01693469 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 5,962E-03 0,01691472 ! musculoskeletal movement GO:0050881 14 9 0,000 5,962E-03 0,01689479 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 5,962E-03 0,01687492 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 5,962E-03 0,01685509 ! regulation of synaptogenesis GO:0051963 15 9 0,000 5,962E-03 0,01683531 ! purine base metabolic process GO:0006144 21 9 0,000 5,962E-03 0,01681557 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 5,962E-03 0,01679588 ! pigment granule transport GO:0051904 17 9 0,000 5,962E-03 0,01677623 ! regulation of fibrinolysis GO:0051917 16 9 0,000 5,962E-03 0,01675664 ! regulation of telomere maintenance GO:0032204 14 9 0,000 5,962E-03 0,01673708 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 5,962E-03 0,01671758 ! regulation of muscle adaptation GO:0043502 14 9 0,000 5,962E-03 0,01669811 ! regulation of amino acid transport GO:0051955 11 9 0,000 5,962E-03 0,0166787 ! mitochondrion localization GO:0051646 15 9 0,000 5,962E-03 0,01665933 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 6,622E-03 0,01848306 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 6,622E-03 0,01846164 ! negative regulation of blood pressure GO:0045776 26 10 0,000 6,622E-03 0,01844028 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 6,622E-03 0,01841896 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 6,622E-03 0,01839769 ! regulation of phosphatase activity GO:0010921 28 10 0,000 6,622E-03 0,01837647 ! synapsis GO:0007129 13 10 0,000 6,622E-03 0,0183553 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 6,622E-03 0,01833418 ! N-glycan processing GO:0006491 20 10 0,000 6,622E-03 0,0183131 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 6,622E-03 0,01829208 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 6,622E-03 0,0182711 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 6,622E-03 0,01825017 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 6,622E-03 0,01822929 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 6,622E-03 0,01820846 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 6,622E-03 0,01818767 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 6,622E-03 0,01816693 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 6,622E-03 0,01814624 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 6,622E-03 0,0181256 ! androgen metabolic process GO:0008209 17 10 0,000 6,622E-03 0,018105 ! phospholipid efflux GO:0033700 16 10 0,000 6,622E-03 0,01808445 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 6,622E-03 0,01806394 ! positive regulation of heart contraction GO:0045823 16 10 0,000 6,622E-03 0,01804349 ! lung alveolus development GO:0048286 26 10 0,000 6,622E-03 0,01802307 ! pathogenesis GO:0009405 13 10 0,000 6,622E-03 0,01800271 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 6,622E-03 0,01798239 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 6,622E-03 0,01796212 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 6,622E-03 0,01794189 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 6,622E-03 0,01792171 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 6,622E-03 0,01790157 ! endoderm development GO:0007492 16 10 0,000 6,622E-03 0,01788148 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 6,622E-03 0,01786143 ! arginine catabolic process GO:0006527 13 10 0,000 6,622E-03 0,01784143 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 6,622E-03 0,01782147 ! proline metabolic process GO:0006560 13 10 0,000 6,622E-03 0,01780156 ! glucan biosynthetic process GO:0009250 14 10 0,000 6,622E-03 0,01778169 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 6,622E-03 0,01776187 ! polyamine biosynthetic process GO:0006596 12 10 0,000 6,622E-03 0,01774209 ! V(D)J recombination GO:0033151 28 10 0,000 6,622E-03 0,01772236 ! reverse cholesterol transport GO:0043691 16 10 0,000 6,622E-03 0,01770266 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 6,622E-03 0,01768302 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 6,622E-03 0,01766341 ! B cell proliferation GO:0042100 18 10 0,000 6,622E-03 0,01764385 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 6,622E-03 0,01762433 ! regulation of sodium ion transport GO:0002028 21 10 0,000 6,622E-03 0,01760486 ! multicellular organism growth GO:0035264 18 10 0,000 6,622E-03 0,01758543 ! phagocytosis, engulfment GO:0006911 28 10 0,000 6,622E-03 0,01756604 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 6,622E-03 0,01754669 ! epithelial cell development GO:0002064 20 10 0,000 6,622E-03 0,01752739 ! lens development in camera-type eye GO:0002088 16 10 0,000 6,622E-03 0,01750813 ! retinoic acid metabolic process GO:0042573 14 10 0,000 6,622E-03 0,01748891 ! macroautophagy GO:0016236 17 10 0,000 6,622E-03 0,01746973 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 6,622E-03 0,0174506 ! positive regulation of translational initiation GO:0045948 11 10 0,000 6,622E-03 0,01743151 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 6,622E-03 0,01741246 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 6,622E-03 0,01739345 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 6,622E-03 0,01737448 ! copper ion homeostasis GO:0055070 13 10 0,000 6,622E-03 0,01735555 ! regulation of bone resorption GO:0045124 25 10 0,000 6,622E-03 0,01733667 ! regulation of gliogenesis GO:0014013 23 10 0,000 6,622E-03 0,01731782 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 6,622E-03 0,01729902 ! alpha-beta T cell activation GO:0046631 23 10 0,000 6,622E-03 0,01728026 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 6,622E-03 0,01726154 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 6,622E-03 0,01724286 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 6,622E-03 0,01722421 ! blastoderm segmentation GO:0007350 18 10 0,000 6,622E-03 0,01720561 ! response to dsRNA GO:0043331 20 10 0,000 6,622E-03 0,01718705 ! DNA ligation GO:0006266 19 10 0,000 6,622E-03 0,01716853 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 6,622E-03 0,01715005 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 6,622E-03 0,01713161 ! melanosome localization GO:0032400 16 10 0,000 6,622E-03 0,01711321 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 6,622E-03 0,01709485 ! regulation of B cell differentiation GO:0045577 19 10 0,000 6,622E-03 0,01707653 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 6,622E-03 0,01705824 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 6,622E-03 0,01704 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 6,622E-03 0,01702179 ! mRNA cleavage GO:0006379 17 10 0,000 6,622E-03 0,01700363 ! protein sumoylation GO:0016925 15 10 0,000 6,622E-03 0,0169855 ! hindbrain morphogenesis GO:0021575 19 10 0,000 6,622E-03 0,01696741 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 6,622E-03 0,01694936 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 6,622E-03 0,01693135 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 6,622E-03 0,01691337 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 6,622E-03 0,01689544 ! salivary gland development GO:0007431 27 10 0,000 6,622E-03 0,01687754 ! prophase GO:0051324 15 10 0,000 6,622E-03 0,01685968 ! negative regulation of neurological system process GO:0031645 19 10 0,000 6,622E-03 0,01684186 ! apical protein localization GO:0045176 15 10 0,000 6,622E-03 0,01682407 ! ubiquinone metabolic process GO:0006743 15 10 0,000 6,622E-03 0,01680633 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 6,622E-03 0,01678862 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 6,622E-03 0,01677095 ! midbrain development GO:0030901 13 10 0,000 6,622E-03 0,01675331 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 6,622E-03 0,01673571 ! methionine biosynthetic process GO:0009086 19 10 0,000 6,622E-03 0,01671815 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 6,622E-03 0,01670063 ! quaternary ammonium group transport GO:0015697 21 10 0,000 6,622E-03 0,01668314 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 6,622E-03 0,01666569 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 6,622E-03 0,01664827 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 6,622E-03 0,0166309 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 6,622E-03 0,01661355 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 6,622E-03 0,01659625 ! oocyte development GO:0048599 17 10 0,000 6,622E-03 0,01657898 ! establishment of pigment granule localization GO:0051905 18 10 0,000 6,622E-03 0,01656174 ! blastocyst formation GO:0001825 17 10 0,000 6,622E-03 0,01654455 ! cerebellar cortex development GO:0021695 15 10 0,000 6,622E-03 0,01652738 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 6,622E-03 0,01651026 ! activation of innate immune response GO:0002218 12 10 0,000 6,622E-03 0,01649317 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of amine transport GO:0051954 16 10 0,000 6,622E-03 0,01647611 ! response to nicotine GO:0035094 20 10 0,000 6,622E-03 0,01645909 ! establishment of cell polarity GO:0030010 16 10 0,000 6,622E-03 0,0164421 ! negative regulation of immune effector process GO:0002698 20 10 0,000 6,622E-03 0,01642515 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 6,622E-03 0,01640824 ! localization within membrane GO:0051668 20 10 0,000 6,622E-03 0,01639136 ! negative regulation of muscle development GO:0048635 20 11 0,000 7,282E-03 0,01800628 ! respiratory burst GO:0045730 17 11 0,000 7,282E-03 0,0179878 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 7,282E-03 0,01796935 ! neuron fate specification GO:0048665 17 11 0,000 7,282E-03 0,01795094 ! telencephalon cell migration GO:0022029 20 11 0,000 7,282E-03 0,01793256 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 7,282E-03 0,01791423 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 7,282E-03 0,01789593 ! thyroid gland development GO:0030878 26 11 0,000 7,282E-03 0,01787767 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 7,282E-03 0,01785944 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 7,282E-03 0,01784126 ! Golgi vesicle budding GO:0048194 22 11 0,000 7,282E-03 0,01782311 ! response to pain GO:0048265 24 11 0,000 7,282E-03 0,01780499 ! detection of mechanical stimulus GO:0050982 22 11 0,000 7,282E-03 0,01778692 ! T cell proliferation GO:0042098 26 11 0,000 7,282E-03 0,01776888 ! blood vessel remodeling GO:0001974 29 11 0,000 7,282E-03 0,01775088 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 7,282E-03 0,01773291 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 7,282E-03 0,01771498 ! bone resorption GO:0045453 16 11 0,000 7,282E-03 0,01769708 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 7,282E-03 0,01767923 ! ventral spinal cord development GO:0021517 21 11 0,000 7,282E-03 0,01766141 ! negative regulation of proteolysis GO:0045861 25 11 0,000 7,282E-03 0,01764362 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 7,282E-03 0,01762587 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 7,282E-03 0,01760815 ! melanocyte differentiation GO:0030318 21 11 0,000 7,282E-03 0,01759048 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 7,282E-03 0,01757283 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 7,282E-03 0,01755522 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 7,282E-03 0,01753765 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 7,282E-03 0,01752011 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 7,282E-03 0,01750261 ! lipid digestion GO:0044241 18 11 0,000 7,282E-03 0,01748514 ! substrate-bound cell migration GO:0006929 13 11 0,000 7,282E-03 0,01746771 ! UV protection GO:0009650 19 11 0,000 7,282E-03 0,01745031 ! adult heart development GO:0007512 14 11 0,000 7,282E-03 0,01743295 ! chondrocyte differentiation GO:0002062 24 11 0,000 7,282E-03 0,01741562 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 7,282E-03 0,01739833 ! temperature homeostasis GO:0001659 17 11 0,000 7,282E-03 0,01738107 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 7,282E-03 0,01736384 ! negative regulation of ossification GO:0030279 26 11 0,000 7,282E-03 0,01734665 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 7,282E-03 0,01732949 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 7,282E-03 0,01731237 ! regulation of organ growth GO:0046620 13 11 0,000 7,282E-03 0,01729528 ! pigment granule localization GO:0051875 20 11 0,000 7,282E-03 0,01727822 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 7,282E-03 0,0172612 ! vasoconstriction GO:0042310 18 11 0,000 7,282E-03 0,01724421 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 7,282E-03 0,01722725 ! embryonic axis specification GO:0000578 18 11 0,000 7,282E-03 0,01721033 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 7,282E-03 0,01719344 ! snRNA metabolic process GO:0016073 24 11 0,000 7,282E-03 0,01717658 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 7,282E-03 0,01715976 ! nitric oxide metabolic process GO:0046209 15 11 0,000 7,282E-03 0,01714297 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 7,282E-03 0,01712621 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 7,282E-03 0,01710949 ! zymogen activation GO:0031638 15 11 0,000 7,282E-03 0,01709279 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 7,282E-03 0,01707613 ! neuroblast proliferation GO:0007405 24 11 0,000 7,282E-03 0,01705951 ! nucleosome positioning GO:0016584 15 11 0,000 7,282E-03 0,01704291 ! regulation of isotype switching GO:0045191 22 11 0,000 7,282E-03 0,01702635 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 7,282E-03 0,01700982 ! glutathione biosynthetic process GO:0006750 13 11 0,000 7,282E-03 0,01699332 ! regulation of leukocyte migration GO:0002685 26 11 0,000 7,282E-03 0,01697685 ! acid secretion GO:0046717 18 11 0,000 7,282E-03 0,01696042 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 7,282E-03 0,01694402 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 7,282E-03 0,01692765 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 7,282E-03 0,01691131 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 7,282E-03 0,016895 ! oocyte differentiation GO:0009994 18 11 0,000 7,282E-03 0,01687872 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 7,282E-03 0,01686248 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 7,282E-03 0,01684626 ! cholesterol efflux GO:0033344 19 11 0,000 7,282E-03 0,01683008 ! anterior/posterior axis specification GO:0009948 18 11 0,000 7,282E-03 0,01681393 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 7,282E-03 0,01679781 ! negative regulation of glucose import GO:0046325 17 11 0,000 7,282E-03 0,01678172 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 7,282E-03 0,01676566 ! embryonic gut development GO:0048566 15 11 0,000 7,282E-03 0,01674963 ! regulation of organic acid transport GO:0032890 18 11 0,000 7,282E-03 0,01673363 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 7,282E-03 0,01671767 ! cardiac cell differentiation GO:0035051 31 11 0,000 7,282E-03 0,01670173 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 7,282E-03 0,01668582 ! defense response to fungus GO:0050832 13 11 0,000 7,282E-03 0,01666995 ! developmental induction GO:0031128 19 11 0,000 7,282E-03 0,0166541 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 7,282E-03 0,01663828 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 7,282E-03 0,0166225 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 7,282E-03 0,01660674 ! sequestering of metal ion GO:0051238 14 11 0,000 7,282E-03 0,01659102 ! lamellipodium assembly GO:0030032 20 11 0,000 7,282E-03 0,01657532 ! regulation of embryonic development GO:0045995 27 11 0,000 7,282E-03 0,01655965 ! nucleus localization GO:0051647 19 11 0,000 7,282E-03 0,01654402 ! regulation of synapse organization GO:0050807 17 11 0,000 7,282E-03 0,01652841 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 7,941E-03 0,01800832 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 7,941E-03 0,01799136 ! positive regulation of blood pressure GO:0045777 17 12 0,000 7,941E-03 0,01797444 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 7,941E-03 0,01795754 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 7,941E-03 0,01794068 ! virus-host interaction GO:0019048 29 12 0,000 7,941E-03 0,01792385 ! regulation of B cell proliferation GO:0030888 20 12 0,000 7,941E-03 0,01790705 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 7,941E-03 0,01789029 ! cartilage condensation GO:0001502 20 12 0,000 7,941E-03 0,01787355 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 7,941E-03 0,01785685 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 7,941E-03 0,01784017 ! protein complex disassembly GO:0043241 27 12 0,000 7,941E-03 0,01782353 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 7,941E-03 0,01780692 ! regulation of cell projection assembly GO:0060491 30 12 0,000 7,941E-03 0,01779034 ! hippocampus development GO:0021766 26 12 0,000 7,941E-03 0,01777379 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 7,941E-03 0,01775727 ! cytokine biosynthetic process GO:0042089 21 12 0,000 7,941E-03 0,01774079 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 7,941E-03 0,01772433 ! positive regulation of cell growth GO:0030307 22 12 0,000 7,941E-03 0,0177079 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 7,941E-03 0,01769151 ! regulation of exit from mitosis GO:0007096 17 12 0,000 7,941E-03 0,01767514 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 7,941E-03 0,01765881 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 7,941E-03 0,0176425 ! drug transport GO:0015893 16 12 0,000 7,941E-03 0,01762622 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 7,941E-03 0,01760998 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 7,941E-03 0,01759376 ! tyrosine metabolic process GO:0006570 16 12 0,000 7,941E-03 0,01757758 ! polyamine metabolic process GO:0006595 17 12 0,000 7,941E-03 0,01756142 ! focal adhesion formation GO:0048041 35 12 0,000 7,941E-03 0,0175453 ! mitotic spindle organization GO:0007052 21 12 0,000 7,941E-03 0,0175292 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 7,941E-03 0,01751313 ! forebrain cell migration GO:0021885 21 12 0,000 7,941E-03 0,01749709 ! asymmetric protein localization GO:0008105 20 12 0,000 7,941E-03 0,01748109 ! membrane protein proteolysis GO:0033619 25 12 0,000 7,941E-03 0,01746511 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 7,941E-03 0,01744916 ! entry into host cell GO:0030260 32 12 0,000 7,941E-03 0,01743324 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 7,941E-03 0,01741734 ! monoamine transport GO:0015844 18 12 0,000 7,941E-03 0,01740148 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 7,941E-03 0,01738565 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 7,941E-03 0,01736984 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 7,941E-03 0,01735407 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 7,941E-03 0,01733832 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 7,941E-03 0,0173226 ! protein targeting to peroxisome GO:0006625 23 12 0,000 7,941E-03 0,01730691 ! protein homotetramerization GO:0051289 21 12 0,000 7,941E-03 0,01729125 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 7,941E-03 0,01727561 ! regulation of phagocytosis GO:0050764 16 12 0,000 7,941E-03 0,01726001 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 7,941E-03 0,01724443 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 7,941E-03 0,01722888 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 7,941E-03 0,01721336 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 7,941E-03 0,01719786 ! cranial nerve development GO:0021545 20 12 0,000 7,941E-03 0,0171824 ! fucose catabolic process GO:0019317 22 12 0,000 7,941E-03 0,01716696 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 7,941E-03 0,01715155 ! histone acetylation GO:0016573 26 12 0,000 7,941E-03 0,01713617 ! histone methylation GO:0016571 26 12 0,000 7,941E-03 0,01712081 ! mRNA polyadenylation GO:0006378 23 12 0,000 7,941E-03 0,01710549 ! autonomic nervous system development GO:0048483 24 12 0,000 7,941E-03 0,01709019 ! gland morphogenesis GO:0022612 29 12 0,000 7,941E-03 0,01707491 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 7,941E-03 0,01705967 ! peptidyl-lysine modification GO:0018205 21 12 0,000 7,941E-03 0,01704445 ! T cell homeostasis GO:0043029 25 12 0,000 7,941E-03 0,01702926 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 7,941E-03 0,01701409 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 7,941E-03 0,01699896 ! spleen development GO:0048536 22 12 0,000 7,941E-03 0,01698385 ! digestive tract morphogenesis GO:0048546 26 12 0,000 7,941E-03 0,01696876 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 7,941E-03 0,01695371 ! regulation of RNA splicing GO:0043484 20 12 0,000 7,941E-03 0,01693868 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 7,941E-03 0,01692367 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 7,941E-03 0,0169087 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 7,941E-03 0,01689375 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 7,941E-03 0,01687882 ! response to cold GO:0009409 17 12 0,000 7,941E-03 0,01686393 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 7,941E-03 0,01684905 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 7,941E-03 0,01683421 ! cGMP metabolic process GO:0046068 18 13 0,000 8,6E-03 0,01821526 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 8,6E-03 0,01819924 ! regulation of chemokine production GO:0032642 18 13 0,000 8,6E-03 0,01818325 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 8,6E-03 0,01816729 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 8,6E-03 0,01815135 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 8,6E-03 0,01813544 ! lipid localization GO:0010876 28 13 0,000 8,6E-03 0,01811956 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 8,6E-03 0,01810371 ! organelle fusion GO:0048284 32 13 0,000 8,6E-03 0,01808788 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 8,6E-03 0,01807209 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 8,6E-03 0,01805632 ! pseudouridine synthesis GO:0001522 17 13 0,000 8,6E-03 0,01804057 ! endocrine pancreas development GO:0031018 22 13 0,000 8,6E-03 0,01802486 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 8,6E-03 0,01800917 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 8,6E-03 0,01799351 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 8,6E-03 0,01797788 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 8,6E-03 0,01796227 ! methionine metabolic process GO:0006555 27 13 0,000 8,6E-03 0,0179467 ! plasma membrane organization GO:0007009 24 13 0,000 8,6E-03 0,01793114 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 8,6E-03 0,01791562 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 8,6E-03 0,01790012 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 8,6E-03 0,01788465 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 8,6E-03 0,01786921 ! cell-cell junction assembly GO:0007043 27 13 0,000 8,6E-03 0,01785379 ! response to X-ray GO:0010165 25 13 0,000 8,6E-03 0,0178384 ! cytokine metabolic process GO:0042107 22 13 0,000 8,6E-03 0,01782303 ! exocrine system development GO:0035272 32 13 0,000 8,6E-03 0,01780769 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 8,6E-03 0,01779238 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 8,6E-03 0,0177771 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 8,6E-03 0,01776184 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 8,6E-03 0,0177466 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 8,6E-03 0,0177314 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 8,6E-03 0,01771622 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 8,6E-03 0,01770106 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 8,6E-03 0,01768593 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 8,6E-03 0,01767083 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 8,6E-03 0,01765575 ! regulation of cellular pH GO:0030641 22 13 0,000 8,6E-03 0,0176407 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 8,6E-03 0,01762567 ! ribosome assembly GO:0042255 17 13 0,000 8,6E-03 0,01761067 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 8,6E-03 0,0175957 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 8,6E-03 0,01758075 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 8,6E-03 0,01756582 ! chromatin silencing GO:0006342 26 13 0,000 8,6E-03 0,01755092 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 8,6E-03 0,01753605 ! regulation of epidermis development GO:0045682 19 13 0,000 8,6E-03 0,0175212 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 8,6E-03 0,01750638 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 8,6E-03 0,01749158 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 8,6E-03 0,01747681 ! regulation of mRNA stability GO:0043488 31 13 0,000 8,6E-03 0,01746206 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 8,6E-03 0,01744734 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 8,6E-03 0,01743264 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 8,6E-03 0,01741796 ! mRNA 3'-end processing GO:0031124 24 13 0,000 8,6E-03 0,01740331 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 8,6E-03 0,01738869 ! embryonic placenta development GO:0001892 23 13 0,000 8,6E-03 0,01737409 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 8,6E-03 0,01735951 ! insulin secretion GO:0030073 23 13 0,000 8,6E-03 0,01734496 ! actin filament polymerization GO:0030041 24 13 0,000 8,6E-03 0,01733044 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 8,6E-03 0,01731593 ! acrosome reaction GO:0007340 18 13 0,000 8,6E-03 0,01730145 ! rRNA transcription GO:0009303 25 14 0,000 9,259E-03 0,0186109 ! lactation GO:0007595 26 14 0,000 9,259E-03 0,01859537 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 9,259E-03 0,01857986 ! reproductive cellular process GO:0048610 20 14 0,000 9,259E-03 0,01856438 ! tRNA modification GO:0006400 20 14 0,000 9,259E-03 0,01854892 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 9,259E-03 0,01853349 ! regulation of S phase GO:0033261 23 14 0,000 9,259E-03 0,01851808 ! water transport GO:0006833 21 14 0,000 9,259E-03 0,0185027 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 9,259E-03 0,01848735 ! non-recombinational repair GO:0000726 25 14 0,000 9,259E-03 0,01847202 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 9,259E-03 0,01845671 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 9,259E-03 0,01844143 ! retina development in camera-type eye GO:0060041 27 14 0,000 9,259E-03 0,01842618 ! hair follicle morphogenesis GO:0031069 26 14 0,000 9,259E-03 0,01841095 ! RNA polyadenylation GO:0043631 30 14 0,000 9,259E-03 0,01839575 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 9,259E-03 0,01838057 ! palate development GO:0060021 31 14 0,000 9,259E-03 0,01836542 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 9,259E-03 0,01835029 ! regulated secretory pathway GO:0045055 23 14 0,000 9,259E-03 0,01833519 ! regulation of mRNA processing GO:0050684 24 14 0,000 9,259E-03 0,01832011 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 9,259E-03 0,01830505 ! arginine metabolic process GO:0006525 17 14 0,000 9,259E-03 0,01829003 ! regulation of heart rate GO:0002027 24 14 0,000 9,259E-03 0,01827502 ! organic alcohol transport GO:0015850 29 14 0,000 9,259E-03 0,01826004 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 9,259E-03 0,01824509 ! negative regulation of caspase activity GO:0043154 22 14 0,000 9,259E-03 0,01823016 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 9,259E-03 0,01821525 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 9,259E-03 0,01820037 ! neutral amino acid transport GO:0015804 26 14 0,000 9,259E-03 0,01818551 ! L-amino acid transport GO:0015807 30 14 0,000 9,259E-03 0,01817068 ! bone mineralization GO:0030282 17 14 0,000 9,259E-03 0,01815587 ! stem cell development GO:0048864 43 14 0,000 9,259E-03 0,01814108 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 9,259E-03 0,01812632 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 9,259E-03 0,01811159 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 9,259E-03 0,01809687 ! cerebellum development GO:0021549 21 14 0,000 9,259E-03 0,01808218 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 9,259E-03 0,01806752 ! negative regulation of protein secretion GO:0050709 28 14 0,000 9,259E-03 0,01805288 ! response to gamma radiation GO:0010332 28 14 0,000 9,259E-03 0,01803826 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 9,259E-03 0,01802367 ! cofactor transport GO:0051181 26 14 0,000 9,259E-03 0,0180091 ! NADP metabolic process GO:0006739 24 14 0,000 9,259E-03 0,01799455 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 9,259E-03 0,01798002 ! protein-chromophore linkage GO:0018298 19 14 0,000 9,259E-03 0,01796552 ! intestinal absorption GO:0050892 25 14 0,000 9,259E-03 0,01795105 ! cAMP biosynthetic process GO:0006171 23 14 0,000 9,259E-03 0,01793659 ! oxygen transport GO:0015671 21 14 0,000 9,259E-03 0,01792216 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 9,259E-03 0,01790776 ! male genitalia development GO:0030539 24 14 0,000 9,259E-03 0,01789337 ! regulation of RNA stability GO:0043487 32 14 0,000 9,259E-03 0,01787901 ! regulation of axon extension GO:0030516 37 14 0,000 9,259E-03 0,01786468 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 9,259E-03 0,01785036 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 9,259E-03 0,01783607 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 9,917E-03 0,01908877 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 9,917E-03 0,01907351 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 9,917E-03 0,01905828 ! superoxide anion generation GO:0042554 20 15 0,000 9,917E-03 0,01904307 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 9,917E-03 0,01902788 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 9,917E-03 0,01901272 ! phospholipid catabolic process GO:0009395 22 15 0,000 9,917E-03 0,01899758 ! copper ion transport GO:0006825 20 15 0,000 9,917E-03 0,01898247 ! heterophilic cell adhesion GO:0007157 39 15 0,000 9,917E-03 0,01896738 ! cardiac muscle contraction GO:0060048 26 15 0,000 9,917E-03 0,01895231 ! sulfate transport GO:0008272 23 15 0,000 9,917E-03 0,01893727 ! response to cAMP GO:0051591 22 15 0,000 9,917E-03 0,01892225 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 9,917E-03 0,01890726 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 9,917E-03 0,01889229 ! ciliary or flagellar motility GO:0001539 20 15 0,000 9,917E-03 0,01887734 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 9,917E-03 0,01886242 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 9,917E-03 0,01884752 ! response to hexose stimulus GO:0009746 22 15 0,000 9,917E-03 0,01883265 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 9,917E-03 0,01881779 ! glycoprotein catabolic process GO:0006516 26 15 0,000 9,917E-03 0,01880296 ! pituitary gland development GO:0021983 29 15 0,000 9,917E-03 0,01878816 ! vesicle coating GO:0006901 33 15 0,000 9,917E-03 0,01877338 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 9,917E-03 0,01875862 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 9,917E-03 0,01874388 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 9,917E-03 0,01872917 ! regulation of exocytosis GO:0017157 22 15 0,000 9,917E-03 0,01871448 ! G1/S transition checkpoint GO:0031575 40 15 0,000 9,917E-03 0,01869981 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 9,917E-03 0,01868517 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 9,917E-03 0,01867055 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 9,917E-03 0,01865595 ! regulation of vasodilation GO:0042312 26 15 0,000 9,917E-03 0,01864138 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 9,917E-03 0,01862682 ! histone deacetylation GO:0016575 20 15 0,000 9,917E-03 0,01861229 ! mRNA splice site selection GO:0006376 38 15 0,000 9,917E-03 0,01859779 ! tissue regeneration GO:0042246 26 15 0,000 9,917E-03 0,0185833 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 9,917E-03 0,01856884 ! water homeostasis GO:0030104 27 15 0,000 9,917E-03 0,0185544 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 9,917E-03 0,01853999 ! muscle maintenance GO:0046716 26 15 0,000 9,917E-03 0,01852559 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 9,917E-03 0,01851122 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 9,917E-03 0,01849687 ! regulation of ATPase activity GO:0043462 21 15 0,000 9,917E-03 0,01848254 ! dopamine metabolic process GO:0042417 35 15 0,000 9,917E-03 0,01846824 ! heme biosynthetic process GO:0006783 29 15 0,000 9,917E-03 0,01845395 ! lymphocyte homeostasis GO:0002260 30 15 0,000 9,917E-03 0,01843969 ! detection of bacterium GO:0016045 18 15 0,000 9,917E-03 0,01842545 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 9,917E-03 0,01841124 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 9,917E-03 0,01839704 ! L-fucose metabolic process GO:0042354 30 15 0,000 9,917E-03 0,01838287 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 9,917E-03 0,01836872 ! peptide hormone processing GO:0016486 23 15 0,000 9,917E-03 0,01835459 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,01057509 0,01955701 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,01057509 0,01954199 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,01057509 0,01952699 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,01057509 0,01951202 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,01057509 0,01949707 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,01057509 0,01948214 ! bone remodeling GO:0046849 27 16 0,000 0,01057509 0,01946723 ! filopodium assembly GO:0046847 32 16 0,000 0,01057509 0,01945235 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,01057509 0,01943749 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,01057509 0,01942265 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,01057509 0,01940784 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,01057509 0,01939304 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,01057509 0,01937827 ! startle response GO:0001964 28 16 0,000 0,01057509 0,01936353 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,01057509 0,0193488 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,01057509 0,0193341 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,01057509 0,01931942 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,01057509 0,01930476 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,01057509 0,01929012 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,01057509 0,01927551 ! protein polyubiquitination GO:0000209 34 16 0,000 0,01057509 0,01926092 ! glutamate metabolic process GO:0006536 22 16 0,000 0,01057509 0,01924635 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,01057509 0,0192318 ! response to osmotic stress GO:0006970 25 16 0,000 0,01057509 0,01921728 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,01057509 0,01920277 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,01057509 0,01918829 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,01057509 0,01917383 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,01057509 0,01915939 ! intermediate filament-based process GO:0045103 32 16 0,000 0,01057509 0,01914498 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,01057509 0,01913058 ! negative regulation of immune response GO:0050777 35 16 0,000 0,01057509 0,01911621 ! axon cargo transport GO:0008088 43 16 0,000 0,01057509 0,01910186 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,01057509 0,01908753 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,01057509 0,01907322 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,01057509 0,01905893 ! DNA replication initiation GO:0006270 27 16 0,000 0,01057509 0,01904467 ! neuron recognition GO:0008038 35 16 0,000 0,01057509 0,01903042 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,01057509 0,0190162 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,01057509 0,019002 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,01057509 0,01898782 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,01057509 0,01897366 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,01057509 0,01895952 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,01057509 0,0189454 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,01057509 0,0189313 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,01057509 0,01891723 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,01057509 0,01890317 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,01057509 0,01888914 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,01057509 0,01887513 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,01057509 0,01886114 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,01057509 0,01884717 ! defense response to virus GO:0051607 37 16 0,000 0,01057509 0,01883321 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,0112325 0,01998919 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,0112325 0,01997442 ! metencephalon development GO:0022037 30 17 0,000 0,0112325 0,01995966 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,0112325 0,01994493 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,0112325 0,01993023 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,0112325 0,01991554 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,0112325 0,01990087 ! signal complex assembly GO:0007172 41 17 0,000 0,0112325 0,01988623 ! endothelial cell migration GO:0043542 28 17 0,000 0,0112325 0,01987161 ! inositol metabolic process GO:0006020 28 17 0,000 0,0112325 0,01985701 ! gene silencing by RNA GO:0031047 36 17 0,000 0,0112325 0,01984243 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,0112325 0,01982787 ! glial cell development GO:0021782 27 17 0,000 0,0112325 0,01981333 ! limbic system development GO:0021761 36 17 0,000 0,0112325 0,01979882 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,0112325 0,01978432 ! adult walking behavior GO:0007628 33 17 0,000 0,0112325 0,01976985 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,0112325 0,0197554 ! heart looping GO:0001947 30 17 0,000 0,0112325 0,01974097 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,0112325 0,01972656 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,0112325 0,01971217 ! myoblast differentiation GO:0045445 45 17 0,000 0,0112325 0,0196978 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,0112325 0,01968346 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,0112325 0,01966913 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,0112325 0,01965483 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,0112325 0,01964054 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,0112325 0,01962628 ! glycine metabolic process GO:0006544 28 17 0,000 0,0112325 0,01961204 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,0112325 0,01959781 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,0112325 0,01958361 ! NAD metabolic process GO:0019674 29 17 0,000 0,0112325 0,01956943 ! membrane budding GO:0006900 37 17 0,000 0,0112325 0,01955527 ! DNA integration GO:0015074 29 17 0,000 0,0112325 0,01954113 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,0112325 0,01952701 ! regulation of protein binding GO:0043393 33 17 0,000 0,0112325 0,01951291 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,0112325 0,01949884 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,0112325 0,01948478 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,0112325 0,01947074 ! genitalia development GO:0048806 30 17 0,000 0,0112325 0,01945672 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,0112325 0,01944272 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,0112325 0,01942875 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,0112325 0,01941479 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,0112325 0,01940085 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,0112325 0,01938693 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,0112325 0,01937304 ! steroid catabolic process GO:0006706 31 17 0,000 0,0112325 0,01935916 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,0112325 0,0193453 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,0112325 0,01933146 ! gas transport GO:0015669 25 17 0,000 0,0112325 0,01931765 ! organic cation transport GO:0015695 31 17 0,000 0,0112325 0,01930385 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,0112325 0,01929007 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,0112325 0,01927631 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,0112325 0,01926257 ! microspike assembly GO:0030035 36 17 0,000 0,0112325 0,01924885 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,0112325 0,01923515 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,0112325 0,01922147 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,01188948 0,02033127 ! neuron maturation GO:0042551 42 18 0,000 0,01188948 0,02031683 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,01188948 0,02030241 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,01188948 0,02028801 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,01188948 0,02027364 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,01188948 0,02025928 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,01188948 0,02024494 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,01188948 0,02023062 ! memory GO:0007613 31 18 0,000 0,01188948 0,02021632 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,01188948 0,02020205 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,01188948 0,02018779 ! patterning of blood vessels GO:0001569 39 18 0,000 0,01188948 0,02017355 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,01188948 0,02015934 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,01188948 0,02014514 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,01188948 0,02013096 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,01188948 0,02011681 ! glutamine metabolic process GO:0006541 29 18 0,000 0,01188948 0,02010267 ! response to retinoic acid GO:0032526 26 18 0,000 0,01188948 0,02008855 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,01188948 0,02007446 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,01188948 0,02006038 ! response to fungus GO:0009620 21 18 0,000 0,01188948 0,02004632 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,01188948 0,02003228 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,01188948 0,02001826 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,01188948 0,02000427 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,01188948 0,01999029 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,01188948 0,01997633 ! vitamin transport GO:0051180 27 18 0,000 0,01188948 0,01996239 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,01188948 0,01994847 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,01188948 0,01993456 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,01188948 0,01992068 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,01188948 0,01990682 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,01188948 0,01989298 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,01188948 0,01987915 ! nerve development GO:0021675 28 18 0,000 0,01188948 0,01986535 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,01188948 0,01985156 ! protein secretion GO:0009306 39 19 0,000 0,01254606 0,0209333 ! positive regulation of translation GO:0045727 30 19 0,000 0,01254606 0,02091879 ! negative regulation of defense response GO:0031348 25 19 0,000 0,01254606 0,0209043 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,01254606 0,02088984 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,01254606 0,02087539 ! skin development GO:0043588 36 19 0,000 0,01254606 0,02086096 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,01254606 0,02084656 ! lipid phosphorylation GO:0046834 35 19 0,000 0,01254606 0,02083217 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,01254606 0,0208178 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,01254606 0,02080346 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,01254606 0,02078913 ! bile acid metabolic process GO:0008206 29 19 0,000 0,01254606 0,02077482 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,01254606 0,02076053 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,01254606 0,02074627 ! cerebral cortex development GO:0021987 36 19 0,000 0,01254606 0,02073202 ! pigmentation during development GO:0048066 41 19 0,000 0,01254606 0,02071779 ! response to vitamin A GO:0033189 27 19 0,000 0,01254606 0,02070358 ! heme metabolic process GO:0042168 36 19 0,000 0,01254606 0,02068939 ! actin filament bundle formation GO:0051017 42 19 0,000 0,01254606 0,02067522 ! neuromuscular junction development GO:0007528 34 19 0,000 0,01254606 0,02066107 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,01254606 0,02064693 ! plasma membrane fusion GO:0045026 28 19 0,000 0,01254606 0,02063282 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,01254606 0,02061873 ! peptide cross-linking GO:0018149 37 19 0,000 0,01254606 0,02060465 ! protein export from nucleus GO:0006611 36 19 0,000 0,01254606 0,0205906 ! heart process GO:0003015 30 19 0,000 0,01254606 0,02057656 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,01254606 0,02056254 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,01254606 0,02054855 ! visual learning GO:0008542 36 19 0,000 0,01254606 0,02053457 ! cellular pigmentation GO:0033059 36 19 0,000 0,01254606 0,02052061 ! G1 phase GO:0051318 40 19 0,000 0,01254606 0,02050667 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,01254606 0,02049275 ! cell-cell junction organization GO:0045216 35 19 0,000 0,01254606 0,02047884 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,01254606 0,02046496 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,01254606 0,02045109 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,01254606 0,02043725 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,01254606 0,02042342 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,01254606 0,02040961 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,01254606 0,02039582 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,01254606 0,02038205 ! cilium assembly GO:0042384 37 19 0,000 0,01254606 0,0203683 ! peptide hormone secretion GO:0030072 31 19 0,000 0,01254606 0,02035456 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,01320222 0,02140467 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,01320222 0,02139026 ! positive regulation of ossification GO:0045778 47 20 0,000 0,01320222 0,02137586 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,01320222 0,02136149 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,01320222 0,02134713 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,01320222 0,0213328 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,01320222 0,02131848 ! cAMP metabolic process GO:0046058 36 20 0,000 0,01320222 0,02130418 ! response to vitamin GO:0033273 31 20 0,000 0,01320222 0,0212899 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,01320222 0,02127564 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,01320222 0,0212614 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,01320222 0,02124718 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,01320222 0,02123298 ! response to alkaloid GO:0043279 38 20 0,000 0,01320222 0,02121879 ! retinoid metabolic process GO:0001523 32 20 0,000 0,01320222 0,02120463 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,01320222 0,02119048 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,01320222 0,02117636 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,01320222 0,02116225 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,01320222 0,02114816 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,01320222 0,02113409 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,01320222 0,02112004 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,01320222 0,021106 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,01320222 0,02109199 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,01320222 0,02107799 ! body fluid secretion GO:0007589 31 20 0,000 0,01320222 0,02106402 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,01320222 0,02105006 ! peptide secretion GO:0002790 35 20 0,000 0,01320222 0,02103612 ! stem cell differentiation GO:0048863 53 20 0,000 0,01320222 0,02102219 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,01320222 0,02100829 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,01320222 0,02099441 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,01320222 0,02098054 ! sensory perception of pain GO:0019233 30 20 0,000 0,01320222 0,02096669 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,01320222 0,02095286 ! diencephalon development GO:0021536 34 20 0,000 0,01320222 0,02093905 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,01320222 0,02092525 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,01320222 0,02091148 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,01320222 0,02089772 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,01320222 0,02088398 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,01320222 0,02087026 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,01320222 0,02085656 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,01320222 0,02084287 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,01320222 0,0208292 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,01320222 0,02081555 ! regulation of glucose import GO:0046324 29 20 0,000 0,01320222 0,02080192 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,01320222 0,02078831 ! actin filament-based movement GO:0030048 43 20 0,000 0,01320222 0,02077471 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,01320222 0,02076113 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,01320222 0,02074757 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,01320222 0,02073403 ! negative regulation of translation GO:0017148 29 20 0,000 0,01320222 0,02072051 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,01320222 0,020707 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,01320222 0,02069351 ! regulation of cell killing GO:0031341 42 21 0,000 0,01385796 0,0217072 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,01385796 0,02169308 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,01385796 0,02167897 ! hormone secretion GO:0046879 38 21 0,000 0,01385796 0,02166488 ! glycerol metabolic process GO:0006071 34 21 0,000 0,01385796 0,02165082 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,01385796 0,02163677 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,01385796 0,02162273 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,01385796 0,02160872 ! axis specification GO:0009798 38 21 0,000 0,01385796 0,02159473 ! ovarian follicle development GO:0001541 35 21 0,000 0,01385796 0,02158075 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,01385796 0,02156679 ! smooth muscle contraction GO:0006939 46 21 0,000 0,01385796 0,02155285 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,01385796 0,02153893 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,01385796 0,02152502 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,01385796 0,02151113 ! cell aging GO:0007569 44 21 0,000 0,01385796 0,02149726 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,01385796 0,02148341 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,01385796 0,02146958 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,01385796 0,02145576 ! cytolysis GO:0019835 24 21 0,000 0,01385796 0,02144197 ! vasodilation GO:0042311 39 21 0,000 0,01385796 0,02142819 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,01385796 0,02141442 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,01385796 0,02140068 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,01385796 0,02138695 ! oogenesis GO:0048477 36 21 0,000 0,01385796 0,02137324 ! DNA modification GO:0006304 34 21 0,000 0,01385796 0,02135955 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,01385796 0,02134588 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,01385796 0,02133222 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,01385796 0,02131858 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,01385796 0,02130496 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,01385796 0,02129135 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,01385796 0,02127776 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,01385796 0,02126419 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,01385796 0,02125064 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,01385796 0,02123711 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,01385796 0,02122359 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,01385796 0,02121009 ! collagen catabolic process GO:0030574 28 21 0,000 0,01385796 0,0211966 ! sperm-egg recognition GO:0035036 21 21 0,000 0,01385796 0,02118314 ! gut development GO:0048565 39 21 0,000 0,01385796 0,02116969 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,01451329 0,02215672 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,01451329 0,02214267 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,01451329 0,02212863 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,01451329 0,02211462 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,01451329 0,02210062 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,01451329 0,02208664 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,01451329 0,02207268 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,01451329 0,02205874 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,01451329 0,02204481 ! regeneration GO:0031099 41 22 0,000 0,01451329 0,0220309 ! keratinization GO:0031424 28 22 0,000 0,01451329 0,02201701 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,01451329 0,02200314 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,01451329 0,02198928 ! sensory perception of taste GO:0050909 28 22 0,000 0,01451329 0,02197545 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,01451329 0,02196162 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,01451329 0,02194782 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,01451329 0,02193403 ! vacuolar transport GO:0007034 36 22 0,000 0,01451329 0,02192027 ! lysosome organization GO:0007040 41 22 0,000 0,01451329 0,02190651 ! central nervous system neuron development GO:0021954 46 22 0,000 0,01451329 0,02189278 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,01451329 0,02187906 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,01451329 0,02186536 ! fucose metabolic process GO:0006004 39 22 0,000 0,01451329 0,02185168 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,01451329 0,02183801 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,01451329 0,02182436 ! ureteric bud development GO:0001657 43 22 0,000 0,01451329 0,02181073 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,01451329 0,02179712 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,01451329 0,02178352 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,01451329 0,02176994 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,01451329 0,02175638 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,01451329 0,02174283 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,01451329 0,0217293 ! sarcomere organization GO:0045214 30 22 0,000 0,01451329 0,02171579 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,01451329 0,02170229 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,01451329 0,02168881 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,01451329 0,02167535 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,01451329 0,0216619 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,01451329 0,02164847 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,01451329 0,02163506 ! protein stabilization GO:0050821 39 22 0,000 0,01451329 0,02162166 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,01516821 0,02258336 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,01516821 0,0225694 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,01516821 0,02255545 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,01516821 0,02254152 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,01516821 0,0225276 ! gluconeogenesis GO:0006094 33 23 0,000 0,01516821 0,0225137 ! viral genome replication GO:0019079 41 23 0,000 0,01516821 0,02249982 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,01516821 0,02248596 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,01516821 0,02247211 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,01516821 0,02245829 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,01516821 0,02244447 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,01516821 0,02243068 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,01516821 0,0224169 ! visual behavior GO:0007632 42 23 0,000 0,01516821 0,02240314 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,01516821 0,0223894 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,01516821 0,02237567 ! response to ethanol GO:0045471 46 23 0,000 0,01516821 0,02236196 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,01516821 0,02234826 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,01516821 0,02233459 ! peroxisome organization GO:0007031 37 23 0,000 0,01516821 0,02232093 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,01516821 0,02230728 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,01516821 0,02229366 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,01516821 0,02228005 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,01516821 0,02226645 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,01516821 0,02225287 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,01516821 0,02223931 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,01516821 0,02222577 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,01516821 0,02221224 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,01516821 0,02219873 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,01516821 0,02218524 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,01516821 0,02217176 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,01516821 0,0221583 ! fatty acid transport GO:0015908 44 23 0,000 0,01516821 0,02214485 ! platelet activation GO:0030168 37 23 0,000 0,01516821 0,02213142 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,01516821 0,02211801 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,01516821 0,02210461 ! hormone transport GO:0009914 40 23 0,000 0,01516821 0,02209123 ! cell-cell recognition GO:0009988 25 23 0,000 0,01516821 0,02207787 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,01516821 0,02206452 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,01516821 0,02205119 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,01516821 0,02203787 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,01516821 0,02202457 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,01516821 0,02201129 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,01582271 0,02294723 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,01582271 0,0229334 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,01582271 0,0229196 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,01582271 0,02290581 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,01582271 0,02289203 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,01582271 0,02287828 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,01582271 0,02286453 ! vesicle docking GO:0048278 47 24 0,000 0,01582271 0,02285081 ! spinal cord development GO:0021510 47 24 0,000 0,01582271 0,0228371 ! vacuole organization GO:0007033 43 24 0,000 0,01582271 0,02282341 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,01582271 0,02280974 ! digestive system process GO:0022600 39 24 0,000 0,01582271 0,02279608 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,01582271 0,02278244 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,01582271 0,02276881 ! regulation of behavior GO:0050795 43 24 0,000 0,01582271 0,0227552 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,01582271 0,02274161 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,01582271 0,02272803 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,01582271 0,02271447 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,01582271 0,02270092 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,01582271 0,0226874 ! membrane depolarization GO:0051899 39 24 0,000 0,01582271 0,02267388 ! pallium development GO:0021543 49 24 0,000 0,01582271 0,02266039 ! pentose metabolic process GO:0019321 35 24 0,000 0,01582271 0,02264691 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,01582271 0,02263344 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,01582271 0,02261999 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,01582271 0,02260656 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,01582271 0,02259315 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,01582271 0,02257975 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,01582271 0,02256636 GO:0033013|tetrapyrrole metabolic process, ! regulation of multi-organism process GO:0043900 36 24 0,000 0,01582271 0,02255299 ! regulation of amine transport GO:0051952 40 24 0,000 0,01582271 0,02253964 ! protein tetramerization GO:0051262 52 24 0,000 0,01582271 0,0225263 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,0164768 0,02344364 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,0164768 0,02342978 ! myelination GO:0042552 45 25 0,000 0,0164768 0,02341594 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,0164768 0,02340212 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,0164768 0,02338831 ! phototransduction GO:0007602 33 25 0,000 0,0164768 0,02337452 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,0164768 0,02336075 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,0164768 0,02334699 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,0164768 0,02333325 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,0164768 0,02331952 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,0164768 0,02330582 ! receptor metabolic process GO:0043112 46 25 0,000 0,0164768 0,02329212 ! chromosome condensation GO:0030261 45 25 0,000 0,0164768 0,02327845 ! response to starvation GO:0042594 42 25 0,000 0,0164768 0,02326478 ! osteoblast differentiation GO:0001649 60 25 0,000 0,0164768 0,02325114 ! neural crest cell development GO:0014032 54 25 0,000 0,0164768 0,02323751 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,0164768 0,0232239 ! negative regulation of cell development GO:0010721 73 25 0,000 0,0164768 0,0232103 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,0164768 0,02319672 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,0164768 0,02318315 ! interaction with host GO:0051701 62 25 0,000 0,0164768 0,0231696 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,0164768 0,02315607 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,0164768 0,02314255 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,0164768 0,02312905 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,0164768 0,02311556 ! immunoglobulin production GO:0002377 55 25 0,000 0,0164768 0,02310209 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,0164768 0,02308864 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,0164768 0,0230752 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,0164768 0,02306178 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,0164768 0,02304837 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,0164768 0,02303498 ! telomere organization GO:0032200 43 25 0,000 0,0164768 0,0230216 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,0164768 0,02300824 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,0164768 0,02299489 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,01713048 0,0238933 ! embryonic pattern specification GO:0009880 44 26 0,000 0,01713048 0,02387946 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,01713048 0,02386563 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,01713048 0,02385182 ! initiation of viral infection GO:0019059 57 26 0,000 0,01713048 0,02383802 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,01713048 0,02382424 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,01713048 0,02381048 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,01713048 0,02379673 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,01713048 0,023783 ! molting cycle process GO:0022404 50 26 0,000 0,01713048 0,02376929 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,01713048 0,02375559 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,01713048 0,0237419 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,01713048 0,02372823 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,01713048 0,02371458 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,01713048 0,02370094 GO:0051297|centrosome organization, ! insulin receptor signaling pathway GO:0008286 64 26 0,000 0,01713048 0,02368732 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,01713048 0,02367372 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,01713048 0,02366013 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,01713048 0,02364655 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,01713048 0,02363299 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,01713048 0,02361945 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,01713048 0,02360592 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,01713048 0,02359241 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,01713048 0,02357891 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,01713048 0,02356543 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,01713048 0,02355197 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,01713048 0,02353852 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,01713048 0,02352508 ! blastocyst development GO:0001824 49 26 0,000 0,01713048 0,02351166 ! leukocyte proliferation GO:0070661 52 26 0,000 0,01713048 0,02349826 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,01713048 0,02348487 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,01713048 0,02347149 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,01778375 0,0243527 ! neuron fate commitment GO:0048663 48 27 0,000 0,01778375 0,02433885 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,01778375 0,02432501 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,01778375 0,02431119 ! iron ion transport GO:0006826 59 27 0,000 0,01778375 0,02429739 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,01778375 0,0242836 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,01778375 0,02426982 ! protein amino acid acylation GO:0043543 55 27 0,000 0,01778375 0,02425606 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,01778375 0,02424232 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,01778375 0,02422859 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,01778375 0,02421488 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,01778375 0,02420119 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,01778375 0,0241875 ! autophagy GO:0006914 41 27 0,000 0,01778375 0,02417384 ! male gonad development GO:0008584 44 27 0,000 0,01778375 0,02416019 ! response to toxin GO:0009636 47 27 0,000 0,01778375 0,02414655 ! primary neural tube formation GO:0014020 51 27 0,000 0,01778375 0,02413294 ! base-excision repair GO:0006284 41 27 0,000 0,01778375 0,02411933 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,01778375 0,02410574 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,01778375 0,02409217 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,01778375 0,02407861 ! glutathione metabolic process GO:0006749 39 27 0,000 0,01778375 0,02406507 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,01778375 0,02405154 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,01778375 0,02403803 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,01778375 0,02402453 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,01778375 0,02401105 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,0184366 0,02487855 ! circadian rhythm GO:0007623 50 28 0,000 0,0184366 0,02486461 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,0184366 0,02485068 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,0184366 0,02483676 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,0184366 0,02482286 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,0184366 0,02480898 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,0184366 0,02479511 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,0184366 0,02478126 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,0184366 0,02476742 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,0184366 0,0247536 ! synaptogenesis GO:0007416 42 28 0,000 0,0184366 0,0247398 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,0184366 0,02472601 ! lipid oxidation GO:0034440 43 28 0,000 0,0184366 0,02471223 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,0184366 0,02469847 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,0184366 0,02468473 ! translational initiation GO:0006413 65 29 0,000 0,01908904 0,02554406 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,01908904 0,02552987 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,01908904 0,02551568 ! regulation of pH GO:0006885 43 29 0,000 0,01908904 0,02550152 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,01908904 0,02548736 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,01908904 0,02547323 ! catechol metabolic process GO:0009712 54 29 0,000 0,01908904 0,02545911 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,01908904 0,025445 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,01908904 0,02543091 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,01908904 0,02541684 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,01908904 0,02540278 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,01908904 0,02538874 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,01908904 0,02537471 ! cell fate determination GO:0001709 60 29 0,000 0,01908904 0,0253607 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,01908904 0,0253467 ! detection of light stimulus GO:0009583 38 29 0,000 0,01908904 0,02533272 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 0,01908904 0,02531876 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,01908904 0,02530481 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,01908904 0,02529087 ! tissue homeostasis GO:0001894 48 29 0,000 0,01908904 0,02527696 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,01908904 0,02526305 ! phenol metabolic process GO:0018958 55 30 0,000 0,01974107 0,0261116 ! zinc ion transport GO:0006829 45 30 0,000 0,01974107 0,02609726 ! membrane docking GO:0022406 61 30 0,000 0,01974107 0,02608293 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,01974107 0,02606861 ! cell junction assembly GO:0034329 78 30 0,000 0,01974107 0,02605431 ! regulation of innate immune response GO:0045088 51 30 0,000 0,01974107 0,02604003 ! acute-phase response GO:0006953 49 30 0,000 0,01974107 0,02602576 ! myofibril assembly GO:0030239 47 30 0,000 0,01974107 0,02601151 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,01974107 0,02599727 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,01974107 0,02598305 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,01974107 0,02596884 ! phospholipid transport GO:0015914 51 30 0,000 0,01974107 0,02595465 ! ensheathment of neurons GO:0007272 57 30 0,000 0,01974107 0,02594047 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,01974107 0,02592631 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,01974107 0,02591217 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,01974107 0,02589804 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,01974107 0,02588393 ! eye morphogenesis GO:0048592 60 30 0,000 0,01974107 0,02586983 ! regulation of B cell activation GO:0050864 50 30 0,000 0,01974107 0,02585575 ! response to heat GO:0009408 50 30 0,000 0,01974107 0,02584168 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,02039268 0,02668015 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,02039268 0,02666565 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,02039268 0,02665117 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,02039268 0,0266367 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,02039268 0,02662224 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,02039268 0,02660781 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,02039268 0,02659339 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,02039268 0,02657898 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,02039268 0,02656459 ! ovulation cycle process GO:0022602 49 31 0,000 0,02039268 0,02655021 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,02039268 0,02653586 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,02039268 0,02652151 ! peptide transport GO:0015833 55 31 0,000 0,02039268 0,02650718 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,02039268 0,02649287 ! iron ion homeostasis GO:0055072 54 31 0,000 0,02039268 0,02647857 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,02039268 0,02646429 ! mesoderm formation GO:0001707 69 31 0,000 0,02039268 0,02645003 ! natural killer cell activation GO:0030101 45 31 0,000 0,02039268 0,02643577 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,02039268 0,02642154 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,02039268 0,02640732 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,02039268 0,02639311 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,02039268 0,02637892 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,02039268 0,02636475 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,02104389 0,02719205 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,02104389 0,02717745 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,02104389 0,02716287 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,02104389 0,02714831 ! cholesterol transport GO:0030301 56 32 0,000 0,02104389 0,02713376 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,02104389 0,02711923 ! spliceosome assembly GO:0000245 67 32 0,000 0,02104389 0,02710471 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,02104389 0,02709021 ! metanephros development GO:0001656 74 32 0,000 0,02104389 0,02707572 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,02104389 0,02706125 ! response to ionizing radiation GO:0010212 65 32 0,000 0,02104389 0,02704679 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,02104389 0,02703235 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,02104389 0,02701793 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,02104389 0,02700352 ! muscle cell development GO:0055001 49 32 0,000 0,02104389 0,02698912 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,02104389 0,02697474 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,02104389 0,02696038 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,02104389 0,02694603 ! ovulation cycle GO:0042698 51 32 0,000 0,02104389 0,0269317 ! peripheral nervous system development GO:0007422 64 32 0,000 0,02104389 0,02691738 ! BMP signaling pathway GO:0030509 64 32 0,000 0,02104389 0,02690308 ! hindbrain development GO:0030902 61 32 0,000 0,02104389 0,02688879 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,02104389 0,02687452 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,02104389 0,02686026 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,02104389 0,02684602 ! gene silencing GO:0016458 65 32 0,000 0,02104389 0,02683179 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,02169468 0,02764693 ! post-embryonic development GO:0009791 69 33 0,000 0,02169468 0,02763229 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,02169468 0,02761767 ! protein targeting to membrane GO:0006612 68 33 0,000 0,02169468 0,02760307 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,02169468 0,02758848 ! ceramide metabolic process GO:0006672 64 33 0,000 0,02169468 0,02757391 ! formation of primary germ layer GO:0001704 72 33 0,000 0,02169468 0,02755935 ! cell fate specification GO:0001708 52 33 0,000 0,02169468 0,0275448 ! sterol transport GO:0015918 57 33 0,000 0,02169468 0,02753028 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,02169468 0,02751576 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,02169468 0,02750127 ! adult locomotory behavior GO:0008344 59 33 0,000 0,02169468 0,02748678 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,02169468 0,02747232 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,02169468 0,02745787 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,02234506 0,02826615 ! glial cell differentiation GO:0010001 63 34 0,000 0,02234506 0,0282513 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,02234506 0,02823646 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,02234506 0,02822164 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,02234506 0,02820683 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,02234506 0,02819204 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,02234506 0,02817727 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,02234506 0,02816251 ! mismatch repair GO:0006298 46 34 0,000 0,02234506 0,02814776 ! spermatid development GO:0007286 63 34 0,000 0,02234506 0,02813303 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,02234506 0,02811832 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,02234506 0,02810362 ! placenta development GO:0001890 53 34 0,000 0,02234506 0,02808894 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,02234506 0,02807427 ! regulation of muscle development GO:0048634 70 35 0,000 0,02299504 0,02887581 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,02299504 0,02886075 ! negative regulation of secretion GO:0051048 63 35 0,000 0,02299504 0,0288457 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,02299504 0,02883067 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,02299504 0,02881565 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,02299504 0,02880065 ! odontogenesis GO:0042476 66 35 0,000 0,02299504 0,02878567 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,02299504 0,0287707 ! female gonad development GO:0008585 58 35 0,000 0,02299504 0,02875575 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,02299504 0,02874081 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,02299504 0,02872589 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,02299504 0,02871098 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,02299504 0,02869609 ! cytokine production GO:0001816 59 35 0,000 0,02299504 0,02868121 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,02299504 0,02866635 ! neural tube formation GO:0001841 67 35 0,000 0,02299504 0,02865151 ! vesicle localization GO:0051648 64 35 0,000 0,02299504 0,02863668 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,0236446 0,02943037 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,0236446 0,02941515 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,0236446 0,02939995 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,0236446 0,02938476 ! cell junction organization GO:0034330 86 36 0,000 0,0236446 0,02936959 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,0236446 0,02935444 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,0236446 0,0293393 ! positive regulation of cell development GO:0010720 80 36 0,000 0,0236446 0,02932418 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,0236446 0,02930907 ! regulation of proteolysis GO:0030162 72 36 0,000 0,0236446 0,02929398 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,0236446 0,0292789 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,0236446 0,02926384 ! aerobic respiration GO:0009060 55 36 0,000 0,0236446 0,02924879 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,0236446 0,02923376 ! embryonic organ development GO:0048568 57 36 0,000 0,0236446 0,02921875 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,0236446 0,02920375 ! RNA export from nucleus GO:0006405 56 37 0,000 0,02429375 0,02999013 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,02429375 0,02997475 ! meiosis I GO:0007127 65 37 0,000 0,02429375 0,02995938 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,02429375 0,02994404 ! sister chromatid segregation GO:0000819 58 37 0,000 0,02429375 0,0299287 ! actomyosin structure organization GO:0031032 62 37 0,000 0,02429375 0,02991339 ! organic anion transport GO:0015711 68 37 0,000 0,02429375 0,02989809 ! tissue remodeling GO:0048771 76 37 0,000 0,02429375 0,0298828 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,02429375 0,02986753 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,02429375 0,02985228 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,02429375 0,02983704 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,02429375 0,02982182 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,02429375 0,02980661 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,02429375 0,02979142 ! glycogen metabolic process GO:0005977 61 37 0,000 0,02429375 0,02977624 ! pigment metabolic process GO:0042440 80 37 0,000 0,02429375 0,02976108 ! spermatid differentiation GO:0048515 66 37 0,000 0,02429375 0,02974593 ! cellular response to insulin stimulus GO:0032869 82 37 0,000 0,02429375 0,0297308 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,02494249 0,03050922 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,02494249 0,03049371 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,02494249 0,03047823 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,02494249 0,03046276 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,02494249 0,0304473 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,02494249 0,03043186 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,02494249 0,03041644 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,02494249 0,03040103 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,02494249 0,03038563 ! lipid homeostasis GO:0055088 67 38 0,000 0,02494249 0,03037026 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,02494249 0,0303549 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,02494249 0,03033955 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,02494249 0,03032422 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,02494249 0,0303089 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,02494249 0,0302936 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,02494249 0,03027832 ! glucan metabolic process GO:0044042 62 38 0,000 0,02494249 0,03026305 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,02559082 0,03103403 ! mammary gland development GO:0030879 86 39 0,000 0,02559082 0,03101839 ! learning GO:0007612 77 39 0,000 0,02559082 0,03100278 ! ear morphogenesis GO:0042471 60 39 0,000 0,02559082 0,03098717 ! organic ether metabolic process GO:0018904 55 39 0,000 0,02559082 0,03097159 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,02559082 0,03095601 ! segmentation GO:0035282 67 39 0,000 0,02559082 0,03094046 ! ion transmembrane transport GO:0034220 66 39 0,000 0,02559082 0,03092492 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,02559082 0,03090939 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,02559082 0,03089389 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,02559082 0,03087839 ! RNA modification GO:0009451 57 39 0,000 0,02559082 0,03086291 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,02559082 0,03084745 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,02623874 0,03161263 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,02623874 0,0315968 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,02623874 0,031581 ! feeding behavior GO:0007631 59 40 0,000 0,02623874 0,03156521 ! negative regulation of binding GO:0051100 72 40 0,000 0,02623874 0,03154943 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,02623874 0,03153367 ! mesenchymal cell development GO:0014031 87 40 0,000 0,02623874 0,03151793 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,02623874 0,0315022 ! maintenance of protein location GO:0045185 91 40 0,000 0,02623874 0,03148649 ! cytokinesis GO:0000910 72 40 0,000 0,02623874 0,03147079 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,02688625 0,03223135 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,02688625 0,0322153 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,02688625 0,03219927 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,02688625 0,03218325 ! gliogenesis GO:0042063 88 41 0,000 0,02688625 0,03216724 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,02688625 0,03215126 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,02688625 0,03213528 ! T cell differentiation GO:0030217 81 41 0,000 0,02688625 0,03211933 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,02688625 0,03210339 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,02688625 0,03208746 ! female gamete generation GO:0007292 61 41 0,000 0,02688625 0,03207156 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,02688625 0,03205566 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,02753336 0,03281092 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,02753336 0,03279468 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,02753336 0,03277845 ! regulation of tube size GO:0035150 71 42 0,000 0,02753336 0,03276224 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,02753336 0,03274605 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,02753336 0,03272987 ! regulation of intracellular protein transport GO:0033157 80 42 0,000 0,02753336 0,03271371 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,02753336 0,03269756 ! neuron migration GO:0001764 79 42 0,000 0,02753336 0,03268143 ! regulation of protein secretion GO:0050708 71 42 0,000 0,02753336 0,03266531 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,02753336 0,03264921 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,02818005 0,03339961 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,02818005 0,03338316 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,02818005 0,03336673 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,02818005 0,03335032 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,02818005 0,03333393 ! glucose transport GO:0015758 65 43 0,000 0,02818005 0,03331754 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,02818005 0,03330118 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,02818005 0,03328483 ! neural tube development GO:0021915 77 43 0,000 0,02818005 0,0332685 ! regulation of epithelial cell proliferation GO:0050678 111 43 0,000 0,02818005 0,03325218 ! striated muscle contraction GO:0006941 77 43 0,000 0,02818005 0,03323588 ! phagocytosis GO:0006909 90 43 0,000 0,02818005 0,0332196 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,02818005 0,03320333 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,02882634 0,0339482 ! hexose transport GO:0008645 67 44 0,000 0,02882634 0,03393159 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,02882634 0,033915 ! male sex differentiation GO:0046661 76 44 0,000 0,02882634 0,03389842 ! double-strand break repair GO:0006302 81 44 0,000 0,02882634 0,03388186 ! biopolymer methylation GO:0043414 84 44 0,000 0,02882634 0,03386532 ! B cell differentiation GO:0030183 107 44 0,000 0,02882634 0,03384879 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,02882634 0,03383228 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,02882634 0,03381578 ! developmental growth GO:0048589 82 44 0,000 0,02882634 0,0337993 ! maintenance of location in cell GO:0051651 97 44 0,000 0,02882634 0,03378284 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,02947221 0,03452295 ! glycolysis GO:0006096 65 45 0,000 0,02947221 0,03450615 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,02947221 0,03448937 ! leukocyte migration GO:0050900 68 45 0,000 0,02947221 0,0344726 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,02947221 0,03445585 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,02947221 0,03443912 ! induction of apoptosis by intracellular signals GO:0008629 93 45 0,000 0,02947221 0,0344224 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,02947221 0,0344057 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,02947221 0,03438901 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,02947221 0,03437235 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,02947221 0,03435569 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,02947221 0,03433905 ! cell growth GO:0016049 84 45 0,000 0,02947221 0,03432243 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,03011768 0,03505716 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 0,000 0,03011768 0,03504021 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,03011768 0,03502327 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,03011768 0,03500635 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,03011768 0,03498945 ! pigmentation GO:0043473 100 46 0,000 0,03011768 0,03497256 ! response to insulin stimulus GO:0032868 95 46 0,000 0,03011768 0,03495569 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,03011768 0,03493884 ! positive regulation of defense response GO:0031349 76 47 0,000 0,03076275 0,03566996 ! endosome transport GO:0016197 108 47 0,000 0,03076275 0,03565278 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,03076275 0,03563561 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,03076275 0,03561846 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,03076275 0,03560133 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,03076275 0,03558421 ! JNK cascade GO:0007254 91 47 0,000 0,03076275 0,03556711 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,03076275 0,03555003 ! methylation GO:0032259 90 47 0,000 0,03076275 0,03553296 ! protein homooligomerization GO:0051260 76 47 0,000 0,03076275 0,03551591 ! mitochondrial transport GO:0006839 82 48 0,000 0,0314074 0,03624278 ! Notch signaling pathway GO:0007219 96 48 0,000 0,0314074 0,03622541 ! cellular component disassembly GO:0022411 86 48 0,000 0,0314074 0,03620805 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,0314074 0,03619071 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,0314074 0,03617339 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,0314074 0,03615608 ! activation of caspase activity GO:0006919 84 48 0,000 0,0314074 0,03613879 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,0314074 0,03612151 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,0314074 0,03610425 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,0314074 0,03608701 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,0314074 0,03606979 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,03205165 0,03679211 ! regulation of action potential GO:0001508 95 49 0,000 0,03205165 0,03677456 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,03205165 0,03675704 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,03205165 0,03673952 ! regulation of ion transport GO:0043269 77 49 0,000 0,03205165 0,03672203 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,03205165 0,03670455 ! peptide metabolic process GO:0006518 76 49 0,000 0,03205165 0,03668709 ! response to temperature stimulus GO:0009266 76 49 0,000 0,03205165 0,03666964 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,03205165 0,03665222 ! endocrine system development GO:0035270 104 49 0,000 0,03205165 0,0366348 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,03205165 0,03661741 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,03205165 0,03660003 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,03205165 0,03658267 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,03205165 0,03656532 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,03269549 0,03728215 ! neuromuscular process GO:0050905 99 50 0,000 0,03269549 0,03726449 ! regulation of ossification GO:0030278 117 50 0,000 0,03269549 0,03724685 ! inner ear development GO:0048839 79 50 0,000 0,03269549 0,03722922 ! histone modification GO:0016570 91 50 0,000 0,03269549 0,03721161 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,03269549 0,03719401 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,03269549 0,03717644 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,03269549 0,03715888 ! positive regulation of binding GO:0051099 78 51 0,000 0,03333892 0,03787226 ! viral infectious cycle GO:0019058 99 51 0,000 0,03333892 0,03785438 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,03333892 0,03783653 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,03333892 0,03781869 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,03333892 0,03780087 ! excretion GO:0007588 83 51 0,000 0,03333892 0,03778306 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,03333892 0,03776527 ! chromatin remodeling GO:0006338 109 51 0,000 0,03333892 0,0377475 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,03333892 0,03772974 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,03333892 0,03771201 ! vesicle organization GO:0016050 107 51 0,000 0,03333892 0,03769428 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,03333892 0,03767658 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 0,000 0,03333892 0,03765889 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,03333892 0,03764122 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,03398194 0,03834923 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,03398194 0,03833125 ! membrane fusion GO:0006944 110 52 0,000 0,03398194 0,03831329 ! positive regulation of growth GO:0045927 90 52 0,000 0,03398194 0,03829534 ! covalent chromatin modification GO:0016569 101 52 0,000 0,03398194 0,03827741 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,03398194 0,0382595 ! amino acid activation GO:0043038 92 52 0,000 0,03398194 0,03824161 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,03398194 0,03822373 ! synapse organization GO:0050808 85 52 0,000 0,03398194 0,03820587 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,03462456 0,03891018 ! RNA catabolic process GO:0006401 93 53 0,000 0,03462456 0,03889202 ! regulation of translational initiation GO:0006446 82 53 0,000 0,03462456 0,03887387 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,03462456 0,03885574 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,03462456 0,03883762 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,03462456 0,03881953 ! cell maturation GO:0048469 100 53 0,000 0,03462456 0,03880144 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,03462456 0,03878338 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,03462456 0,03876533 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,03526678 0,03946598 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,03526678 0,03944764 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,03526678 0,03942931 ! cell recognition GO:0008037 85 54 0,000 0,03526678 0,03941099 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,03526678 0,0393927 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,03526678 0,03937442 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,03526678 0,03935615 ! chloride transport GO:0006821 90 55 0,000 0,03590859 0,0400538 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,03590859 0,04003524 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,03590859 0,0400167 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,03590859 0,03999817 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,03590859 0,03997967 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,03590859 0,03996117 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,03590859 0,0399427 ! aging GO:0007568 103 55 0,000 0,03590859 0,03992424 ! gastrulation GO:0007369 112 55 0,000 0,03590859 0,0399058 ! heart morphogenesis GO:0003007 97 55 0,000 0,03590859 0,03988738 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,03590859 0,03986897 ! RNA elongation GO:0006354 79 55 0,000 0,03590859 0,03985058 ! nuclear export GO:0051168 97 55 0,000 0,03590859 0,03983221 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,03590859 0,03981385 ! regulation of actin filament length GO:0030832 105 56 0,000 0,03654999 0,04050634 ! sensory perception of smell GO:0007608 80 56 0,000 0,03654999 0,04048769 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,03654999 0,04046906 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,03654999 0,04045045 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,03654999 0,04043185 ! regulation of DNA replication GO:0006275 101 56 0,000 0,03654999 0,04041327 ! proton transport GO:0015992 94 56 0,000 0,03654999 0,0403947 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,03654999 0,04037616 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,03719098 0,0410654 ! muscle fiber development GO:0048747 112 57 0,000 0,03719098 0,04104656 ! positive regulation of cell migration GO:0030335 126 57 0,000 0,03719098 0,04102774 ! lipid modification GO:0030258 97 57 0,000 0,03719098 0,04100894 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,03719098 0,04099015 ! regulation of intracellular transport GO:0032386 101 57 0,000 0,03719098 0,04097139 ! maintenance of location GO:0051235 118 57 0,000 0,03719098 0,04095264 ! hydrogen transport GO:0006818 97 58 0,000 0,03783158 0,04163896 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,03783158 0,04161992 ! regulation of endocytosis GO:0030100 91 58 0,000 0,03783158 0,0416009 ! adult behavior GO:0030534 99 58 0,000 0,03783158 0,0415819 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,03783158 0,04156291 ! positive regulation of secretion GO:0051047 95 59 0,000 0,03847176 0,04224695 ! regulation of cellular component size GO:0032535 109 59 0,000 0,03847176 0,04222767 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,03847176 0,04220842 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,03847176 0,04218918 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,03847176 0,04216996 ! DNA catabolic process GO:0006308 86 59 0,000 0,03847176 0,04215076 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,03847176 0,04213157 ! establishment of organelle localization GO:0051656 109 59 0,000 0,03847176 0,0421124 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,03911154 0,04279326 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,03911154 0,04277381 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,03911154 0,04275437 ! regulation of heart contraction GO:0008016 110 60 0,000 0,03911154 0,04273496 ! camera-type eye development GO:0043010 116 60 0,000 0,03911154 0,04271556 ! protein amino acid autophosphorylation GO:0046777 141 60 0,000 0,03911154 0,04269618 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,03911154 0,04267681 ! kidney development GO:0001822 122 60 0,000 0,03911154 0,04265747 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,03975092 0,04333517 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,03975092 0,04331554 ! mesoderm development GO:0007498 119 61 0,000 0,03975092 0,04329593 ! tRNA processing GO:0008033 89 61 0,000 0,03975092 0,04327634 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,03975092 0,04325677 ! response to peptide hormone stimulus GO:0043434 122 61 0,000 0,03975092 0,04323721 ! ear development GO:0043583 103 62 0,000 0,04038989 0,04391238 ! viral reproductive process GO:0022415 126 62 0,000 0,04038989 0,04389254 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,04038989 0,04387273 ! gonad development GO:0008406 98 62 0,000 0,04038989 0,04385293 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,04038989 0,04383315 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,04102846 0,04450608 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,04102846 0,04448602 ! detection of external stimulus GO:0009581 91 63 0,000 0,04102846 0,04446598 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,04102846 0,04444596 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,04102846 0,04442596 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,04166663 0,04509668 ! cell redox homeostasis GO:0045454 102 64 0,000 0,04166663 0,0450764 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,04166663 0,04505614 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,04166663 0,0450359 ! positive regulation of cell motion GO:0051272 146 64 0,000 0,04166663 0,04501568 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,04230439 0,04568419 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,04230439 0,04566369 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,04230439 0,04564321 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,04230439 0,04562276 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,04230439 0,04560232 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,04294175 0,04626863 ! actin filament organization GO:0007015 148 66 0,000 0,04294175 0,04624792 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,04294175 0,04622723 ! extracellular matrix organization GO:0030198 133 66 0,000 0,04294175 0,04620655 ! secondary metabolic process GO:0019748 116 66 0,000 0,04294175 0,0461859 ! developmental maturation GO:0021700 116 66 0,000 0,04294175 0,04616526 ! cell projection assembly GO:0030031 120 66 0,000 0,04294175 0,04614464 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,04357871 0,0468082 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,04357871 0,04678731 ! negative regulation of protein kinase activity GO:0006469 130 67 0,000 0,04357871 0,04676644 ! negative regulation of cell growth GO:0030308 132 67 0,000 0,04357871 0,04674559 ! activation of MAPK activity GO:0000187 115 67 0,000 0,04357871 0,04672476 ! lung development GO:0030324 144 67 0,000 0,04357871 0,04670395 ! chromosome segregation GO:0007059 113 67 0,000 0,04357871 0,04668316 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,04357871 0,04666238 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,04357871 0,04664162 ! hexose catabolic process GO:0019320 104 67 0,000 0,04357871 0,04662088 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,04357871 0,04660016 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,04357871 0,04657946 ! adaptive immune response GO:0002250 119 67 0,000 0,04357871 0,04655878 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,04357871 0,04653811 ! amino acid transport GO:0006865 125 68 0,000 0,04421526 0,04719695 ! negative regulation of kinase activity GO:0033673 131 68 0,000 0,04421526 0,04717602 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,04421526 0,0471551 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,04421526 0,04713421 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,04421526 0,04711334 ! viral reproduction GO:0016032 134 68 0,000 0,04421526 0,04709248 ! regulation of lipase activity GO:0060191 130 68 0,000 0,04421526 0,04707164 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,04421526 0,04705083 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,04485141 0,04770667 ! negative regulation of cell size GO:0045792 134 69 0,000 0,04485141 0,04768559 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,04485141 0,04766453 ! urogenital system development GO:0001655 137 69 0,000 0,04485141 0,04764349 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,04485141 0,04762246 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,04485141 0,04760145 ! antigen processing and presentation GO:0019882 104 69 0,000 0,04485141 0,04758047 ! appendage morphogenesis GO:0035107 135 70 0,000 0,04548716 0,04823363 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 0,000 0,04548716 0,04821238 ! amine catabolic process GO:0009310 117 71 0,000 0,04612251 0,04886427 ! reproductive structure development GO:0048608 113 71 0,000 0,04612251 0,04884276 ! appendage development GO:0048736 136 71 0,000 0,04612251 0,04882127 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,04612251 0,0487998 ! B cell activation GO:0042113 160 71 0,000 0,04612251 0,04877835 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,04612251 0,04875692 ! regulation of immune effector process GO:0002697 137 71 0,000 0,04612251 0,04873551 ! acute inflammatory response GO:0002526 113 72 0,000 0,04675745 0,04938474 ! regulation of caspase activity GO:0043281 122 72 0,000 0,04675745 0,04936307 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,04675745 0,04934142 ! carbohydrate transport GO:0008643 110 72 0,000 0,04675745 0,04931978 ! negative regulation of transferase activity GO:0051348 140 72 0,000 0,04675745 0,04929817 ! respiratory system development GO:0060541 153 72 0,000 0,04675745 0,04927658 ! learning or memory GO:0007611 147 73 0,000 0,04739199 0,04992344 ! regulation of blood pressure GO:0008217 125 73 0,000 0,04739199 0,04990159 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,04739199 0,04987976 ! axon guidance GO:0007411 139 73 0,000 0,04739199 0,04985795 ! fertilization GO:0009566 90 73 0,000 0,04739199 0,04983616 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,04802614 0,05048095 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,04802614 0,0504589 ! neurotransmitter transport GO:0006836 123 74 0,000 0,04802614 0,05043688 ! meiosis GO:0007126 121 74 0,000 0,04802614 0,05041487 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,04802614 0,05039288 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,04802614 0,05037092 ! regulation of endopeptidase activity GO:0052548 125 74 0,000 0,04802614 0,05034897 ! eye development GO:0001654 143 74 0,000 0,04802614 0,05032704 ! organelle localization GO:0051640 136 74 0,000 0,04802614 0,05030513 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,04865988 0,05094676 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,04865988 0,0509246 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,04865988 0,05090246 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,04865988 0,05088034 ! meiotic cell cycle GO:0051321 122 75 0,000 0,04865988 0,05085824 ! rhythmic process GO:0048511 128 75 0,000 0,04865988 0,05083615 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,04865988 0,05081409 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,04929322 0,05145314 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,04929322 0,05143082 ! defense response to bacterium GO:0042742 89 76 0,000 0,04929322 0,05140853 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,04929322 0,05138626 ! regulation of catabolic process GO:0009894 161 76 0,000 0,04929322 0,051364 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,04992616 0,05200101 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,04992616 0,05197851 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,04992616 0,05195603 ! blood coagulation GO:0007596 146 78 0,000 0,0505587 0,05259154 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,0505587 0,05256881 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,0505587 0,0525461 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,0505587 0,05252341 ! protein oligomerization GO:0051259 139 78 0,000 0,0505587 0,05250074 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,05119083 0,05313423 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,05119083 0,05311132 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,05119083 0,05308843 ! regulation of peptidase activity GO:0052547 134 79 0,000 0,05119083 0,05306555 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,05119083 0,0530427 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,05182257 0,05367418 ! muscle cell differentiation GO:0042692 159 80 0,000 0,05182257 0,05365108 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,05182257 0,05362801 ! protein import into nucleus GO:0006606 158 80 0,000 0,05182257 0,05360495 ! inorganic anion transport GO:0015698 138 80 0,000 0,05182257 0,05358191 ! T cell activation GO:0042110 168 81 0,000 0,05245391 0,05421139 ! response to hypoxia GO:0001666 171 81 0,000 0,05245391 0,05418811 ! digestion GO:0007586 112 81 0,000 0,05245391 0,05416486 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,05245391 0,05414162 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,05245391 0,0541184 ! nuclear import GO:0051170 161 81 0,000 0,05245391 0,05409521 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,05245391 0,05407203 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,05308485 0,054699 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,05308485 0,05467558 ! response to drug GO:0042493 143 82 0,000 0,05308485 0,05465219 ! response to nutrient GO:0007584 125 82 0,000 0,05308485 0,05462881 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,05308485 0,05460545 ! cellular response to hormone stimulus GO:0032870 167 82 0,000 0,05308485 0,05458212 ! response to oxygen levels GO:0070482 176 83 0,000 0,0537154 0,05520685 ! regulation of lyase activity GO:0051339 160 83 0,000 0,0537154 0,05518328 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,05434554 0,05580681 ! hemostasis GO:0007599 158 84 0,000 0,05434554 0,055783 ! negative regulation of transport GO:0051051 153 84 0,000 0,05434554 0,05575922 ! negative regulation of growth GO:0045926 155 84 0,000 0,05434554 0,05573545 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,05434554 0,0557117 ! nucleosome assembly GO:0006334 122 85 0,000 0,05497528 0,05633327 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,05497528 0,05630929 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,05497528 0,05628533 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,05560463 0,05690546 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,05560463 0,05688126 ! chromatin assembly GO:0031497 124 86 0,000 0,05560463 0,05685709 ! tube morphogenesis GO:0035239 176 86 0,000 0,05560463 0,05683294 ! mitochondrion organization GO:0007005 148 86 0,000 0,05560463 0,0568088 ! amine transport GO:0015837 155 86 0,000 0,05560463 0,05678469 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,05623357 0,05740262 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,05623357 0,05737828 ! protein localization in nucleus GO:0034504 176 87 0,000 0,05623357 0,05735395 ! regulation of protein transport GO:0051223 154 87 0,000 0,05623357 0,05732965 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 135 88 0,000 0,05686212 0,0579459 ! regulation of DNA binding GO:0051101 155 88 0,000 0,05686212 0,05792137 ! gland development GO:0048732 206 88 0,000 0,05686212 0,05789685 ! regulation of neurological system process GO:0031644 148 88 0,000 0,05686212 0,05787236 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,05686212 0,05784789 ! cellular defense response GO:0006968 114 89 0,000 0,05749027 0,05846221 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,05749027 0,05843752 ! regulation of cell adhesion GO:0030155 212 89 0,000 0,05749027 0,05841284 ! ossification GO:0001503 188 90 0,000 0,05811803 0,05902574 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,05811803 0,05900083 ! sex differentiation GO:0007548 145 90 0,000 0,05811803 0,05897595 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,05811803 0,05895109 ! bone development GO:0060348 189 91 0,000 0,05874538 0,05956232 ! sterol metabolic process GO:0016125 152 91 0,000 0,05874538 0,05953723 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,05874538 0,05951217 ! regulation of defense response GO:0031347 149 92 0,000 0,05937234 0,06012199 ! nucleosome organization GO:0034728 138 92 0,000 0,05937234 0,0600967 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,05937234 0,06007143 ! vitamin metabolic process GO:0006766 139 92 0,000 0,05937234 0,06004618 ! positive regulation of MAP kinase activity GO:0043406 160 93 0,000 0,05999891 0,06065436 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,05999891 0,06062888 ! regulation of membrane potential GO:0042391 164 93 0,000 0,05999891 0,06060343 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,05999891 0,060578 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,06062507 0,06118453 ! female pregnancy GO:0007565 164 94 0,000 0,06062507 0,06115888 ! transcription initiation GO:0006352 153 94 0,000 0,06062507 0,06113325 ! regulation of T cell activation GO:0050863 158 94 0,000 0,06062507 0,06110764 ! forebrain development GO:0030900 188 95 0,000 0,06125084 0,06171253 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,06125084 0,0616867 ! leukocyte differentiation GO:0002521 202 96 0,000 0,06187622 0,06229045 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,06187622 0,0622644 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,06187622 0,06223837 ! positive regulation of immune response GO:0050778 156 96 0,000 0,06187622 0,06221236 ! detection of stimulus GO:0051606 151 96 0,000 0,06187622 0,06218637 ! regulation of DNA metabolic process GO:0051052 178 97 0,000 0,0625012 0,06278826 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,0625012 0,06276205 ! protein ubiquitination GO:0016567 217 97 0,000 0,0625012 0,06273587 ! hormone metabolic process GO:0042445 157 97 0,000 0,0625012 0,06270971 ! regulation of protein localization GO:0032880 176 97 0,000 0,0625012 0,06268357 ! response to virus GO:0009615 160 98 0,000 0,06312578 0,06328359 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,06312578 0,06325724 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,06312578 0,0632309 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,06374997 0,06382955 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,06374997 0,063803 ! skeletal muscle tissue development GO:0007519 186 99 0,000 0,06374997 0,06377647 GO:0060538|skeletal muscle organ development, ! cell cycle arrest GO:0007050 213 100 0,000 0,06437376 0,06437376