pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-b1/out-0.05-06-0.01-300-run-b1//th1-pval-1e-01-08-th2-pval-1e-02-02-th3-pval-1e-01-01-run-b1/go_data/8996-10-real-Ivshina_GPL96-GPL97-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! activation of caspase activity by cytochrome c GO:0008635 14 8 2,000 4,472E-09 1,076E-05 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 2,000 5,416E-08 6,516E-05 ! cell structure disassembly during apoptosis GO:0006921 30 21 2,000 1,058E-07 8,487E-05 ! apoptotic nuclear changes GO:0030262 32 22 2,000 1,225E-07 7,368E-05 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 2,000 1,609E-07 7,743E-05 ! nucleus organization GO:0006997 67 38 2,000 6,681E-07 2,679E-04 ! cellular component disassembly GO:0022411 86 48 2,000 1,366E-06 4,695E-04 ! activation of caspase activity GO:0006919 84 48 2,000 1,366E-06 4,108E-04 ! induction of apoptosis by extracellular signals GO:0008624 89 49 2,000 1,455E-06 3,889E-04 ! positive regulation of caspase activity GO:0043280 95 55 2,000 2,068E-06 4,976E-04 GO:0010952|positive regulation of peptidase activity, ! DNA catabolic process GO:0006308 86 59 2,000 2,56E-06 5,599E-04 ! regulation of caspase activity GO:0043281 122 72 2,000 4,679E-06 9,382E-04 ! regulation of endopeptidase activity GO:0052548 125 74 2,000 5,083E-06 9,408E-04 ! regulation of peptidase activity GO:0052547 134 79 2,000 6,193E-06 1,064E-03 ! cellular respiration GO:0045333 135 88 2,000 8,572E-06 1,375E-03 ! induction of apoptosis via death domain receptors GO:0008625 20 16 1,000 2,399E-05 3,607E-03 ! activation of pro-apoptotic gene products GO:0008633 47 23 1,000 5,048E-05 7,145E-03 ! response to heat GO:0009408 50 30 1,000 8,664E-05 0,01158095 ! response to temperature stimulus GO:0009266 76 49 1,000 2,33E-04 0,02951139 ! regulation of translational initiation GO:0006446 82 53 1,000 2,728E-04 0,03281662 ! response to unfolded protein GO:0006986 131 85 1,000 7,007E-04 0,08028479 ! response to protein stimulus GO:0051789 149 91 1,000 8,025E-04 0,08776549 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 2,322E-03 0,24292889 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 2,322E-03 0,23280685 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 2,322E-03 0,22349458 ! positive regulation of helicase activity GO:0051096 11 5 0,000 2,322E-03 0,21489863 ! neuron fate determination GO:0048664 7 5 0,000 2,322E-03 0,20693943 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 2,322E-03 0,19954873 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 2,322E-03 0,19266774 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 2,322E-03 0,18624548 ! polyol transport GO:0015791 12 5 0,000 2,322E-03 0,18023756 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 2,322E-03 0,17460514 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 2,322E-03 0,16931408 ! response to superoxide GO:0000303 10 5 0,000 2,322E-03 0,16433425 ! negative regulation of bone resorption GO:0045779 10 5 0,000 2,322E-03 0,15963899 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 2,322E-03 0,15520457 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 2,322E-03 0,15100985 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 2,322E-03 0,14703591 ! female meiosis GO:0007143 7 5 0,000 2,322E-03 0,14326576 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 2,322E-03 0,13968411 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 2,322E-03 0,13627718 ! cobalt ion transport GO:0006824 11 5 0,000 2,322E-03 0,13303249 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 2,322E-03 0,12993871 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 2,322E-03 0,12698556 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 2,322E-03 0,12416366 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 2,322E-03 0,12146445 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 2,322E-03 0,1188801 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 2,322E-03 0,11640343 ! embryonic camera-type eye development GO:0031076 10 5 0,000 2,322E-03 0,11402785 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 2,322E-03 0,11174729 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 2,322E-03 0,10955617 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 2,322E-03 0,10744932 ! adaptation of signaling pathway GO:0022401 7 5 0,000 2,322E-03 0,10542197 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 2,322E-03 0,10346971 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 2,322E-03 0,10158845 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 2,322E-03 0,09977437 ! negative chemotaxis GO:0050919 14 5 0,000 2,322E-03 0,09802394 ! positive regulation of histone modification GO:0031058 5 5 0,000 2,322E-03 0,09633387 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 2,322E-03 0,09470109 ! sensory perception of bitter taste GO:0050913 7 5 0,000 2,322E-03 0,09312274 ! behavioral response to pain GO:0048266 9 5 0,000 2,322E-03 0,09159614 ! clathrin coat assembly GO:0048268 14 5 0,000 2,322E-03 0,09011878 ! Notch receptor processing GO:0007220 8 5 0,000 2,322E-03 0,08868833 ! regulation of dopamine uptake GO:0051584 9 5 0,000 2,322E-03 0,08730257 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 2,322E-03 0,08595945 ! micturition GO:0060073 9 5 0,000 2,322E-03 0,08465704 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 2,322E-03 0,0833935 ! copulation GO:0007620 9 5 0,000 2,322E-03 0,08216712 ! glial cell fate commitment GO:0021781 13 5 0,000 2,322E-03 0,0809763 ! protein maturation by protein folding GO:0022417 13 5 0,000 2,322E-03 0,07981949 ! spermidine metabolic process GO:0008216 7 5 0,000 2,322E-03 0,07869527 ! regulation of potassium ion transport GO:0043266 10 5 0,000 2,322E-03 0,07760228 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 2,322E-03 0,07653924 ! apoptotic cell clearance GO:0043277 20 5 0,000 2,322E-03 0,07550493 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 2,322E-03 0,07449819 ! lipoprotein particle clearance GO:0034381 10 5 0,000 2,322E-03 0,07351795 ! grooming behavior GO:0007625 6 5 0,000 2,322E-03 0,07256318 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 2,322E-03 0,07163288 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 2,322E-03 0,07072613 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 2,322E-03 0,06984206 ! response to protozoan GO:0001562 10 5 0,000 2,322E-03 0,06897981 ! positive regulation of glycolysis GO:0045821 14 5 0,000 2,322E-03 0,06813859 ! lymph vessel development GO:0001945 10 5 0,000 2,322E-03 0,06731764 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 2,322E-03 0,06651624 ! endochondral ossification GO:0001958 16 5 0,000 2,322E-03 0,0657337 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 2,322E-03 0,06496935 ! parathyroid gland development GO:0060017 13 5 0,000 2,322E-03 0,06422258 ! anagen GO:0042640 6 5 0,000 2,322E-03 0,06349278 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 2,322E-03 0,06277938 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 2,322E-03 0,06208183 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 2,322E-03 0,06139961 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 2,322E-03 0,06073222 ! dorsal spinal cord development GO:0021516 7 5 0,000 2,322E-03 0,06007919 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 2,322E-03 0,05944005 ! sphingoid catabolic process GO:0046521 6 5 0,000 2,322E-03 0,05881436 ! skeletal myofibril assembly GO:0014866 10 5 0,000 2,322E-03 0,05820171 ! smooth muscle tissue development GO:0048745 28 5 0,000 2,322E-03 0,0576017 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 2,322E-03 0,05701392 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 2,322E-03 0,05643803 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 2,322E-03 0,05587364 ! cardiac muscle fiber development GO:0048739 10 5 0,000 2,322E-03 0,05532044 ! transepithelial chloride transport GO:0030321 9 5 0,000 2,322E-03 0,05477808 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 2,322E-03 0,05424626 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 2,322E-03 0,05372466 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 2,322E-03 0,053213 ! neutrophil mediated immunity GO:0002446 7 5 0,000 2,322E-03 0,05271099 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 2,322E-03 0,05221836 ! histidine catabolic process GO:0006548 6 5 0,000 2,322E-03 0,05173486 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 2,322E-03 0,05126022 ! microvillus organization GO:0032528 7 5 0,000 2,322E-03 0,05079422 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 2,322E-03 0,05033662 ! L-serine biosynthetic process GO:0006564 6 5 0,000 2,322E-03 0,04988718 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 2,322E-03 0,0494457 ! tryptophan metabolic process GO:0006568 9 5 0,000 2,322E-03 0,04901197 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 2,322E-03 0,04858578 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 2,322E-03 0,04816694 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 2,322E-03 0,04775525 ! polyol catabolic process GO:0046174 7 5 0,000 2,322E-03 0,04735055 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 2,322E-03 0,04695264 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 2,322E-03 0,04656137 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 2,322E-03 0,04617657 ! muscle cell migration GO:0014812 8 5 0,000 2,322E-03 0,04579807 ! mitochondrial fission GO:0000266 8 5 0,000 2,322E-03 0,04542573 ! sister chromatid cohesion GO:0007062 12 5 0,000 2,322E-03 0,04505939 ! mRNA transcription GO:0009299 9 5 0,000 2,322E-03 0,04469892 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 2,322E-03 0,04434416 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 2,322E-03 0,043995 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 2,322E-03 0,04365129 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 2,322E-03 0,0433129 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 2,322E-03 0,04297973 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 2,322E-03 0,04265164 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 2,322E-03 0,04232852 ! response to food GO:0032094 6 5 0,000 2,322E-03 0,04201026 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 2,322E-03 0,04169675 ! positive regulation of transporter activity GO:0032411 8 5 0,000 2,322E-03 0,04138789 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 2,322E-03 0,04108356 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 2,322E-03 0,04078368 ! paraxial mesoderm development GO:0048339 14 5 0,000 2,322E-03 0,04048815 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 2,322E-03 0,04019687 ! forebrain neuron development GO:0021884 13 5 0,000 2,322E-03 0,03990975 ! lipoprotein catabolic process GO:0042159 11 5 0,000 2,322E-03 0,0396267 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 2,322E-03 0,03934764 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 2,322E-03 0,03907248 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 2,322E-03 0,03880114 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 2,322E-03 0,03853355 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 2,322E-03 0,03826962 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 2,322E-03 0,03800928 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 2,322E-03 0,03775246 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 2,322E-03 0,03749909 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 2,322E-03 0,0372491 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 2,322E-03 0,03700241 ! basic amino acid transport GO:0015802 11 5 0,000 2,322E-03 0,03675898 ! cellular glucose homeostasis GO:0001678 5 5 0,000 2,322E-03 0,03651872 ! early endosome to late endosome transport GO:0045022 12 5 0,000 2,322E-03 0,03628159 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 2,322E-03 0,03604751 ! depyrimidination GO:0045008 10 5 0,000 2,322E-03 0,03581644 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 2,322E-03 0,03558831 ! regulation of centrosome cycle GO:0046605 7 5 0,000 2,322E-03 0,03536307 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 2,322E-03 0,03514066 ! zinc ion homeostasis GO:0055069 8 5 0,000 2,322E-03 0,03492103 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 2,322E-03 0,03470413 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 2,322E-03 0,0344899 ! forebrain morphogenesis GO:0048853 13 5 0,000 2,322E-03 0,03427831 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 2,322E-03 0,0340693 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 2,322E-03 0,03386282 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 2,322E-03 0,03365882 ! peptidyl-arginine modification GO:0018195 9 5 0,000 2,322E-03 0,03345727 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 2,322E-03 0,03325812 ! positive regulation of organ growth GO:0046622 6 5 0,000 2,322E-03 0,03306133 ! response to arsenic GO:0046685 10 5 0,000 2,322E-03 0,03286685 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 2,322E-03 0,03267465 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 2,322E-03 0,03248468 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 2,322E-03 0,0322969 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 2,322E-03 0,03211129 ! response to cadmium ion GO:0046686 7 5 0,000 2,322E-03 0,0319278 ! bile acid biosynthetic process GO:0006699 6 5 0,000 2,322E-03 0,03174639 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 2,322E-03 0,03156703 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 2,322E-03 0,03138969 ! decidualization GO:0046697 11 5 0,000 2,322E-03 0,03121433 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 2,322E-03 0,03104091 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 2,322E-03 0,03086942 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 2,322E-03 0,0306998 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 2,322E-03 0,03053205 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 2,322E-03 0,03036611 ! base conversion or substitution editing GO:0016553 5 5 0,000 2,322E-03 0,03020197 ! neural tube patterning GO:0021532 7 5 0,000 2,322E-03 0,03003959 ! embryonic cleavage GO:0040016 6 5 0,000 2,322E-03 0,02987895 ! peroxisome fission GO:0016559 5 5 0,000 2,322E-03 0,02972002 ! histone demethylation GO:0016577 10 5 0,000 2,322E-03 0,02956278 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 2,322E-03 0,02940718 ! mitotic recombination GO:0006312 9 5 0,000 2,322E-03 0,02925322 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 2,322E-03 0,02910086 ! metaphase plate congression GO:0051310 7 5 0,000 2,322E-03 0,02895008 ! regulation of sterol transport GO:0032371 7 5 0,000 2,322E-03 0,02880085 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 2,322E-03 0,02865315 ! enteric nervous system development GO:0048484 8 5 0,000 2,322E-03 0,02850696 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 2,322E-03 0,02836226 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 2,322E-03 0,02821901 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 2,322E-03 0,02807721 ! muscle cell proliferation GO:0033002 11 5 0,000 2,322E-03 0,02793682 ! skeletal muscle regeneration GO:0043403 8 5 0,000 2,322E-03 0,02779783 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 2,322E-03 0,02766022 ! plasminogen activation GO:0031639 5 5 0,000 2,322E-03 0,02752396 ! B cell homeostasis GO:0001782 13 5 0,000 2,322E-03 0,02738904 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 2,322E-03 0,02725544 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 2,322E-03 0,02712313 ! metaphase GO:0051323 8 5 0,000 2,322E-03 0,0269921 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 2,322E-03 0,02686233 ! cellular response to nutrient GO:0031670 8 5 0,000 2,322E-03 0,0267338 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 2,322E-03 0,0266065 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 2,322E-03 0,0264804 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 2,322E-03 0,02635549 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 2,322E-03 0,02623176 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 2,322E-03 0,02610918 ! response to redox state GO:0051775 5 5 0,000 2,322E-03 0,02598774 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 2,322E-03 0,02586743 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 2,322E-03 0,02574822 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 2,322E-03 0,02563011 ! regulation of telomerase activity GO:0051972 6 5 0,000 2,322E-03 0,02551308 ! galactolipid metabolic process GO:0019374 7 5 0,000 2,322E-03 0,02539711 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 2,322E-03 0,02528219 ! porphyrin catabolic process GO:0006787 12 5 0,000 2,322E-03 0,02516831 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 2,322E-03 0,02505545 ! striatum development GO:0021756 9 5 0,000 2,322E-03 0,02494359 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 2,322E-03 0,02483273 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 2,322E-03 0,02472285 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 2,322E-03 0,02461394 ! glial cell migration GO:0008347 11 5 0,000 2,322E-03 0,02450598 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 2,322E-03 0,02439897 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 2,322E-03 0,02429289 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 2,322E-03 0,02418773 ! somatic stem cell maintenance GO:0035019 15 5 0,000 2,322E-03 0,02408347 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 2,322E-03 0,02398011 ! negative regulation of lipase activity GO:0060192 8 5 0,000 2,322E-03 0,02387763 ! neuroprotection GO:0043526 6 5 0,000 2,322E-03 0,02377602 ! neural plate development GO:0001840 8 5 0,000 2,322E-03 0,02367527 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 2,322E-03 0,02357538 ! regulation of sensory perception GO:0051931 7 5 0,000 2,322E-03 0,02347632 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 2,322E-03 0,02337809 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 2,322E-03 0,02328069 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 2,322E-03 0,02318408 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 2,322E-03 0,02308828 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 2,322E-03 0,02299327 ! sequestering of calcium ion GO:0051208 7 5 0,000 2,322E-03 0,02289903 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 2,322E-03 0,02280557 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 2,322E-03 0,02271286 ! spindle assembly GO:0051225 6 5 0,000 2,322E-03 0,02262091 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 2,322E-03 0,0225297 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 2,322E-03 0,02243921 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 2,322E-03 0,02234946 ! drug metabolic process GO:0017144 6 5 0,000 2,322E-03 0,02226042 ! stem cell division GO:0017145 11 5 0,000 2,322E-03 0,02217208 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 2,322E-03 0,02208444 ! organ regeneration GO:0031100 7 5 0,000 2,322E-03 0,0219975 ! carnitine metabolic process GO:0009437 7 5 0,000 2,322E-03 0,02191123 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 2,322E-03 0,02182564 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 2,322E-03 0,02174072 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 2,786E-03 0,02598213 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 2,786E-03 0,02588182 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 2,786E-03 0,02578227 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 2,786E-03 0,02568349 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 2,786E-03 0,02558546 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 2,786E-03 0,02548818 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 2,786E-03 0,02539163 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 2,786E-03 0,02529581 ! sleep GO:0030431 13 6 0,000 2,786E-03 0,02520072 ! response to oxygen radical GO:0000305 11 6 0,000 2,786E-03 0,02510633 ! positive regulation of axon extension GO:0045773 11 6 0,000 2,786E-03 0,02501265 ! myoblast cell fate commitment GO:0048625 16 6 0,000 2,786E-03 0,02491967 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 2,786E-03 0,02482737 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 2,786E-03 0,02473576 ! regulation of interferon-beta production GO:0032648 8 6 0,000 2,786E-03 0,02464482 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 2,786E-03 0,02455454 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 2,786E-03 0,02446493 ! forebrain regionalization GO:0021871 8 6 0,000 2,786E-03 0,02437597 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 2,786E-03 0,02428765 ! male meiosis GO:0007140 7 6 0,000 2,786E-03 0,02419997 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 2,786E-03 0,02411292 ! response to zinc ion GO:0010043 9 6 0,000 2,786E-03 0,02402649 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 2,786E-03 0,02394068 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 2,786E-03 0,02385548 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 2,786E-03 0,02377089 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 2,786E-03 0,02368689 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 2,786E-03 0,02360349 ! malate metabolic process GO:0006108 11 6 0,000 2,786E-03 0,02352067 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 2,786E-03 0,02343843 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 2,786E-03 0,02335676 ! protein refolding GO:0042026 15 6 0,000 2,786E-03 0,02327566 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 2,786E-03 0,02319512 ! opsonization GO:0008228 8 6 0,000 2,786E-03 0,02311514 ! mating behavior GO:0007617 7 6 0,000 2,786E-03 0,02303571 ! neuron remodeling GO:0016322 15 6 0,000 2,786E-03 0,02295682 ! erythrocyte maturation GO:0043249 7 6 0,000 2,786E-03 0,02287847 ! embryonic hemopoiesis GO:0035162 14 6 0,000 2,786E-03 0,02280065 ! equilibrioception GO:0050957 14 6 0,000 2,786E-03 0,02272336 ! protein amino acid dealkylation GO:0008214 12 6 0,000 2,786E-03 0,02264659 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 2,786E-03 0,02257034 ! photoreceptor cell development GO:0042461 10 6 0,000 2,786E-03 0,0224946 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 2,786E-03 0,02241937 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 2,786E-03 0,02234464 ! response to interferon-gamma GO:0034341 15 6 0,000 2,786E-03 0,0222704 ! toxin metabolic process GO:0009404 11 6 0,000 2,786E-03 0,02219666 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 2,786E-03 0,0221234 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 2,786E-03 0,02205063 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 2,786E-03 0,02197833 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 2,786E-03 0,02190651 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 2,786E-03 0,02183515 ! cGMP-mediated signaling GO:0019934 13 6 0,000 2,786E-03 0,02176426 ! activation of MAPKKK activity GO:0000185 12 6 0,000 2,786E-03 0,02169382 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 2,786E-03 0,02162384 ! thymic T cell selection GO:0045061 12 6 0,000 2,786E-03 0,02155431 ! protein lipoylation GO:0009249 10 6 0,000 2,786E-03 0,02148523 ! cysteine metabolic process GO:0006534 10 6 0,000 2,786E-03 0,02141658 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 2,786E-03 0,02134838 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 2,786E-03 0,0212806 ! glutamate catabolic process GO:0006538 10 6 0,000 2,786E-03 0,02121326 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 2,786E-03 0,02114634 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 2,786E-03 0,02107984 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 2,786E-03 0,02101376 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 2,786E-03 0,0209481 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 2,786E-03 0,02088284 ! hyperosmotic response GO:0006972 9 6 0,000 2,786E-03 0,02081798 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 2,786E-03 0,02075353 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 2,786E-03 0,02068948 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 2,786E-03 0,02062582 ! urea metabolic process GO:0019627 7 6 0,000 2,786E-03 0,02056255 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 2,786E-03 0,02049967 ! neutrophil activation GO:0042119 8 6 0,000 2,786E-03 0,02043717 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 2,786E-03 0,02037505 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 2,786E-03 0,0203133 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 2,786E-03 0,02025194 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 2,786E-03 0,02019094 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 2,786E-03 0,0201303 ! neuron apoptosis GO:0051402 9 6 0,000 2,786E-03 0,02007003 ! nucleoside salvage GO:0043174 9 6 0,000 2,786E-03 0,02001012 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 2,786E-03 0,01995057 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 2,786E-03 0,01989137 ! T cell mediated immunity GO:0002456 16 6 0,000 2,786E-03 0,01983252 ! negative regulation of platelet activation GO:0010544 9 6 0,000 2,786E-03 0,01977401 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 2,786E-03 0,01971585 ! carnitine transport GO:0015879 10 6 0,000 2,786E-03 0,01965804 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 2,786E-03 0,01960056 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 2,786E-03 0,01954341 ! positive regulation of exocytosis GO:0045921 8 6 0,000 2,786E-03 0,0194866 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 2,786E-03 0,01943012 ! 5S class rRNA transcription GO:0042791 11 6 0,000 2,786E-03 0,01937396 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 2,786E-03 0,01931813 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 2,786E-03 0,01926262 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 2,786E-03 0,01920742 ! sodium ion homeostasis GO:0055078 11 6 0,000 2,786E-03 0,01915254 ! establishment of spindle localization GO:0051293 12 6 0,000 2,786E-03 0,01909798 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 2,786E-03 0,01904372 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 2,786E-03 0,01898977 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 2,786E-03 0,01893613 ! neural nucleus development GO:0048857 14 6 0,000 2,786E-03 0,01888279 ! response to UV-C GO:0010225 11 6 0,000 2,786E-03 0,01882975 ! astrocyte development GO:0014002 15 6 0,000 2,786E-03 0,018777 ! protein targeting to lysosome GO:0006622 10 6 0,000 2,786E-03 0,01872455 ! purine base biosynthetic process GO:0009113 17 6 0,000 2,786E-03 0,0186724 ! interaction with symbiont GO:0051702 13 6 0,000 2,786E-03 0,01862053 ! regulation of dendrite development GO:0050773 16 6 0,000 2,786E-03 0,01856895 ! skeletal muscle contraction GO:0003009 6 6 0,000 2,786E-03 0,01851765 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 2,786E-03 0,01846664 ! response to copper ion GO:0046688 10 6 0,000 2,786E-03 0,01841591 ! response to exogenous dsRNA GO:0043330 10 6 0,000 2,786E-03 0,01836545 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 2,786E-03 0,01831527 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 2,786E-03 0,01826537 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 2,786E-03 0,01821574 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 2,786E-03 0,01816637 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 2,786E-03 0,01811727 ! regulation of dopamine secretion GO:0014059 14 6 0,000 2,786E-03 0,01806844 ! nucleoside catabolic process GO:0009164 7 6 0,000 2,786E-03 0,01801987 ! hair follicle maturation GO:0048820 7 6 0,000 2,786E-03 0,01797156 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 2,786E-03 0,0179235 ! Schwann cell development GO:0014044 15 6 0,000 2,786E-03 0,01787571 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 2,786E-03 0,01782817 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 2,786E-03 0,01778088 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 2,786E-03 0,01773384 ! subpallium development GO:0021544 10 6 0,000 2,786E-03 0,01768705 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 2,786E-03 0,0176405 ! histone ubiquitination GO:0016574 8 6 0,000 2,786E-03 0,0175942 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 2,786E-03 0,01754814 ! maintenance of organ identity GO:0048496 9 6 0,000 2,786E-03 0,01750233 ! G2 phase GO:0051319 16 6 0,000 2,786E-03 0,01745675 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 2,786E-03 0,0174114 ! establishment of planar polarity GO:0001736 7 6 0,000 2,786E-03 0,0173663 ! regulation of mast cell activation GO:0033003 12 6 0,000 2,786E-03 0,01732142 ! membrane to membrane docking GO:0022614 14 6 0,000 2,786E-03 0,01727678 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 2,786E-03 0,01723237 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 2,786E-03 0,01718818 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 2,786E-03 0,01714422 ! receptor internalization GO:0031623 10 6 0,000 2,786E-03 0,01710049 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 2,786E-03 0,01705697 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 2,786E-03 0,01701368 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 2,786E-03 0,01697061 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 2,786E-03 0,01692775 ! protein deubiquitination GO:0016579 14 6 0,000 2,786E-03 0,01688511 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 2,786E-03 0,01684269 ! protein destabilization GO:0031648 9 6 0,000 2,786E-03 0,01680048 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 2,786E-03 0,01675848 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 2,786E-03 0,01671668 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 2,786E-03 0,0166751 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 2,786E-03 0,01663372 ! progesterone metabolic process GO:0042448 10 6 0,000 2,786E-03 0,01659255 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 2,786E-03 0,01655158 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 2,786E-03 0,01651081 ! negative regulation of axon extension GO:0030517 21 6 0,000 2,786E-03 0,01647025 ! removal of superoxide radicals GO:0019430 11 6 0,000 2,786E-03 0,01642988 ! triglyceride catabolic process GO:0019433 10 6 0,000 2,786E-03 0,01638971 ! determination of adult lifespan GO:0008340 15 6 0,000 2,786E-03 0,01634973 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 2,786E-03 0,01630995 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 2,786E-03 0,01627037 ! cerebellar cortex formation GO:0021697 8 6 0,000 2,786E-03 0,01623097 ! catecholamine transport GO:0051937 9 6 0,000 2,786E-03 0,01619176 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 2,786E-03 0,01615275 ! sensory cilium assembly GO:0035058 10 6 0,000 2,786E-03 0,01611392 ! organ or tissue specific immune response GO:0002251 7 6 0,000 2,786E-03 0,01607528 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 2,786E-03 0,01603682 ! maternal placenta development GO:0001893 12 6 0,000 2,786E-03 0,01599855 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 2,786E-03 0,01596045 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 2,786E-03 0,01592254 ! negative regulation of B cell activation GO:0050869 13 6 0,000 2,786E-03 0,01588481 ! protein amino acid prenylation GO:0018346 16 6 0,000 2,786E-03 0,01584726 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 2,786E-03 0,01580988 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 2,786E-03 0,01577268 ! positive regulation of coagulation GO:0050820 12 6 0,000 2,786E-03 0,01573566 ! tRNA transcription GO:0009304 14 7 0,000 3,25E-03 0,01831132 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 3,25E-03 0,01826854 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 3,25E-03 0,01822596 ! behavioral response to cocaine GO:0048148 14 7 0,000 3,25E-03 0,01818357 ! regulation of helicase activity GO:0051095 15 7 0,000 3,25E-03 0,01814138 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 3,25E-03 0,01809939 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 3,25E-03 0,01805759 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 3,25E-03 0,01801598 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 3,25E-03 0,01797456 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 3,25E-03 0,01793334 ! prostate gland development GO:0030850 13 7 0,000 3,25E-03 0,0178923 ! nucleotide-sugar transport GO:0015780 12 7 0,000 3,25E-03 0,01785145 ! synaptonemal complex assembly GO:0007130 10 7 0,000 3,25E-03 0,01781079 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 3,25E-03 0,01777031 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 3,25E-03 0,01773001 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 3,25E-03 0,0176899 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 3,25E-03 0,01764997 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 3,25E-03 0,01761021 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 3,25E-03 0,01757064 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 3,25E-03 0,01753124 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 3,25E-03 0,01749202 ! SMAD protein complex assembly GO:0007183 12 7 0,000 3,25E-03 0,01745298 ! glycolipid transport GO:0046836 10 7 0,000 3,25E-03 0,01741411 ! protein amino acid sulfation GO:0006477 10 7 0,000 3,25E-03 0,01737541 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 3,25E-03 0,01733688 ! neuron adhesion GO:0007158 12 7 0,000 3,25E-03 0,01729853 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 3,25E-03 0,01726034 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 3,25E-03 0,01722232 ! actin-myosin filament sliding GO:0033275 11 7 0,000 3,25E-03 0,01718447 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 3,25E-03 0,01714679 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 3,25E-03 0,01710927 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 3,25E-03 0,01707191 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 3,25E-03 0,01703472 ! mRNA stabilization GO:0048255 18 7 0,000 3,25E-03 0,01699768 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 3,25E-03 0,01696081 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 3,25E-03 0,0169241 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 3,25E-03 0,01688755 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 3,25E-03 0,01685115 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 3,25E-03 0,01681491 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 3,25E-03 0,01677883 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 3,25E-03 0,0167429 ! lipoprotein transport GO:0042953 14 7 0,000 3,25E-03 0,01670713 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 3,25E-03 0,0166715 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 3,25E-03 0,01663603 ! rhythmic behavior GO:0007622 15 7 0,000 3,25E-03 0,01660071 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 3,25E-03 0,01656554 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 3,25E-03 0,01653052 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 3,25E-03 0,01649564 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 3,25E-03 0,01646092 ! regulation of odontogenesis GO:0042481 13 7 0,000 3,25E-03 0,01642633 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 3,25E-03 0,0163919 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 3,25E-03 0,0163576 ! mechanosensory behavior GO:0007638 14 7 0,000 3,25E-03 0,01632345 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 3,25E-03 0,01628945 ! positive regulation of isotype switching GO:0045830 15 7 0,000 3,25E-03 0,01625558 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 3,25E-03 0,01622186 ! protein-cofactor linkage GO:0018065 13 7 0,000 3,25E-03 0,01618827 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 3,25E-03 0,01615482 ! spinal cord patterning GO:0021511 13 7 0,000 3,25E-03 0,01612152 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 3,25E-03 0,01608834 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 3,25E-03 0,01605531 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 3,25E-03 0,01602241 ! adrenal gland development GO:0030325 17 7 0,000 3,25E-03 0,01598964 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 3,25E-03 0,01595701 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 3,25E-03 0,01592451 ! ovulation GO:0030728 9 7 0,000 3,25E-03 0,01589214 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 3,25E-03 0,01585991 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 3,25E-03 0,0158278 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 3,25E-03 0,01579583 ! microtubule nucleation GO:0007020 20 7 0,000 3,25E-03 0,01576398 ! proline biosynthetic process GO:0006561 10 7 0,000 3,25E-03 0,01573226 ! thyroid hormone generation GO:0006590 13 7 0,000 3,25E-03 0,01570067 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 3,25E-03 0,01566921 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 3,25E-03 0,01563787 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 3,25E-03 0,01560666 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 3,25E-03 0,01557557 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 3,25E-03 0,0155446 ! galactose metabolic process GO:0006012 13 7 0,000 3,25E-03 0,01551376 ! vesicle fusion GO:0006906 17 7 0,000 3,25E-03 0,01548304 ! response to dietary excess GO:0002021 8 7 0,000 3,25E-03 0,01545244 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 3,25E-03 0,01542196 ! intracellular pH reduction GO:0051452 11 7 0,000 3,25E-03 0,0153916 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 3,25E-03 0,01536137 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 3,25E-03 0,01533124 ! organ growth GO:0035265 15 7 0,000 3,25E-03 0,01530124 ! purine salvage GO:0043101 10 7 0,000 3,25E-03 0,01527136 ! nucleoside transport GO:0015858 8 7 0,000 3,25E-03 0,01524159 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 3,25E-03 0,01521194 ! parturition GO:0007567 14 7 0,000 3,25E-03 0,0151824 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 3,25E-03 0,01515297 ! rRNA modification GO:0000154 14 7 0,000 3,25E-03 0,01512366 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 3,25E-03 0,01509447 ! spindle checkpoint GO:0031577 15 7 0,000 3,25E-03 0,01506538 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 3,25E-03 0,01503641 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 3,25E-03 0,01500755 ! macrophage differentiation GO:0030225 11 7 0,000 3,25E-03 0,0149788 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 3,25E-03 0,01495016 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 3,25E-03 0,01492163 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 3,25E-03 0,01489321 ! hyaluronan metabolic process GO:0030212 8 7 0,000 3,25E-03 0,0148649 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 3,25E-03 0,01483669 ! anterograde axon cargo transport GO:0008089 18 7 0,000 3,25E-03 0,01480859 ! fibrinolysis GO:0042730 10 7 0,000 3,25E-03 0,0147806 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 3,25E-03 0,01475271 ! eating behavior GO:0042755 7 7 0,000 3,25E-03 0,01472492 ! B cell lineage commitment GO:0002326 21 7 0,000 3,25E-03 0,01469725 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 3,25E-03 0,01466967 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 3,25E-03 0,0146422 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 3,25E-03 0,01461483 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 3,25E-03 0,01458756 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 3,25E-03 0,0145604 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 3,25E-03 0,01453334 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 3,25E-03 0,01450637 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 3,25E-03 0,01447951 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 3,25E-03 0,01445274 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 3,25E-03 0,01442608 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 3,25E-03 0,01439951 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 3,25E-03 0,01437304 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 3,25E-03 0,01434667 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 3,25E-03 0,01432039 ! regulation of meiosis GO:0040020 12 7 0,000 3,25E-03 0,01429421 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 3,25E-03 0,01426813 ! T cell lineage commitment GO:0002360 16 7 0,000 3,25E-03 0,01424214 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 3,25E-03 0,01421625 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 3,25E-03 0,01419044 ! oxygen homeostasis GO:0032364 12 7 0,000 3,25E-03 0,01416474 ! transcription termination GO:0006353 13 7 0,000 3,25E-03 0,01413912 ! response to tumor cell GO:0002347 13 7 0,000 3,25E-03 0,0141136 ! regulation of respiratory burst GO:0060263 11 7 0,000 3,25E-03 0,01408817 ! coenzyme A metabolic process GO:0015936 12 7 0,000 3,25E-03 0,01406283 ! anaphase GO:0051322 17 7 0,000 3,25E-03 0,01403758 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 3,25E-03 0,01401243 ! axonal fasciculation GO:0007413 18 7 0,000 3,25E-03 0,01398736 ! negative regulation of nuclear division GO:0051784 14 7 0,000 3,25E-03 0,01396238 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 3,25E-03 0,0139375 ! peptidyl-threonine modification GO:0018210 25 7 0,000 3,25E-03 0,0139127 ! diuresis GO:0030146 12 7 0,000 3,25E-03 0,01388798 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 3,25E-03 0,01386336 ! thiamin metabolic process GO:0006772 7 7 0,000 3,25E-03 0,01383882 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 3,25E-03 0,01381437 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 3,25E-03 0,01379001 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 3,25E-03 0,01376573 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 3,25E-03 0,01374154 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 3,25E-03 0,01371743 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 3,25E-03 0,01369341 ! melanin biosynthetic process GO:0042438 8 7 0,000 3,25E-03 0,01366947 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 3,25E-03 0,01364561 ! dopamine biosynthetic process GO:0042416 18 7 0,000 3,25E-03 0,01362184 ! glycolipid catabolic process GO:0019377 15 7 0,000 3,25E-03 0,01359815 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 3,25E-03 0,01357454 ! lymph node development GO:0048535 10 7 0,000 3,25E-03 0,01355101 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 3,25E-03 0,01352757 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 3,25E-03 0,01350421 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 3,25E-03 0,01348092 ! endosome to lysosome transport GO:0008333 11 7 0,000 3,25E-03 0,01345772 ! protein modification by small protein removal GO:0070646 16 7 0,000 3,25E-03 0,0134346 ! adult feeding behavior GO:0008343 9 7 0,000 3,25E-03 0,01341155 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 3,25E-03 0,01338859 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 3,25E-03 0,0133657 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 3,25E-03 0,01334289 ! muscle adaptation GO:0043500 14 7 0,000 3,25E-03 0,01332016 ! embryonic heart tube development GO:0035050 10 7 0,000 3,25E-03 0,01329751 ! retina homeostasis GO:0001895 12 7 0,000 3,25E-03 0,01327493 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 3,25E-03 0,01325243 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 3,25E-03 0,01323001 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 3,25E-03 0,01320766 ! protein prenylation GO:0018342 18 7 0,000 3,25E-03 0,01318539 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 3,25E-03 0,01316319 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 3,25E-03 0,01314107 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 3,25E-03 0,01311902 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 3,713E-03 0,01496482 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 3,713E-03 0,01493979 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 0,000 3,713E-03 0,01491485 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 3,713E-03 0,01489 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 3,713E-03 0,01486522 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 3,713E-03 0,01484053 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 3,713E-03 0,01481592 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 3,713E-03 0,01479139 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 3,713E-03 0,01476694 ! neutral lipid catabolic process GO:0046461 13 8 0,000 3,713E-03 0,01474257 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 3,713E-03 0,01471828 ! meiotic prophase I GO:0007128 13 8 0,000 3,713E-03 0,01469407 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 3,713E-03 0,01466995 ! oligopeptide transport GO:0006857 15 8 0,000 3,713E-03 0,0146459 ! UTP metabolic process GO:0046051 8 8 0,000 3,713E-03 0,01462193 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 3,713E-03 0,01459803 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 3,713E-03 0,01457422 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 3,713E-03 0,01455048 ! macrophage chemotaxis GO:0048246 12 8 0,000 3,713E-03 0,01452683 ! succinate metabolic process GO:0006105 14 8 0,000 3,713E-03 0,01450324 ! membrane hyperpolarization GO:0060081 10 8 0,000 3,713E-03 0,01447974 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 3,713E-03 0,01445631 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 3,713E-03 0,01443295 ! T-helper 1 type immune response GO:0042088 12 8 0,000 3,713E-03 0,01440967 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 3,713E-03 0,01438647 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 3,713E-03 0,01436334 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 3,713E-03 0,01434028 ! ganglioside metabolic process GO:0001573 19 8 0,000 3,713E-03 0,0143173 ! reflex GO:0060004 16 8 0,000 3,713E-03 0,0142944 ! negative regulation of endocytosis GO:0045806 11 8 0,000 3,713E-03 0,01427156 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 3,713E-03 0,0142488 ! endothelial cell differentiation GO:0045446 17 8 0,000 3,713E-03 0,01422611 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 3,713E-03 0,01420349 ! glycerolipid catabolic process GO:0046503 13 8 0,000 3,713E-03 0,01418095 ! hemoglobin metabolic process GO:0020027 13 8 0,000 3,713E-03 0,01415847 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 3,713E-03 0,01413607 ! pigment granule organization GO:0048753 16 8 0,000 3,713E-03 0,01411374 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 3,713E-03 0,01409148 ! astrocyte differentiation GO:0048708 18 8 0,000 3,713E-03 0,01406929 ! histidine metabolic process GO:0006547 16 8 0,000 3,713E-03 0,01404717 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 3,713E-03 0,01402511 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 3,713E-03 0,01400313 ! glycine catabolic process GO:0006546 13 8 0,000 3,713E-03 0,01398122 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 3,713E-03 0,01395937 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 3,713E-03 0,01393759 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 3,713E-03 0,01391588 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 3,713E-03 0,01389424 ! regulation of pigmentation during development GO:0048070 24 8 0,000 3,713E-03 0,01387267 ! melanin metabolic process GO:0006582 15 8 0,000 3,713E-03 0,01385116 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 3,713E-03 0,01382972 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 3,713E-03 0,01380834 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 3,713E-03 0,01378703 ! macrophage activation GO:0042116 12 8 0,000 3,713E-03 0,01376579 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 3,713E-03 0,01374461 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 3,713E-03 0,0137235 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 3,713E-03 0,01370245 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 3,713E-03 0,01368147 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 3,713E-03 0,01366055 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 3,713E-03 0,01363969 ! regulation of vascular permeability GO:0043114 12 8 0,000 3,713E-03 0,0136189 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 3,713E-03 0,01359817 ! osteoblast development GO:0002076 16 8 0,000 3,713E-03 0,0135775 ! positive regulation of vasodilation GO:0045909 13 8 0,000 3,713E-03 0,0135569 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 3,713E-03 0,01353636 ! negative regulation of translational initiation GO:0045947 10 8 0,000 3,713E-03 0,01351588 ! Schwann cell differentiation GO:0014037 19 8 0,000 3,713E-03 0,01349546 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 3,713E-03 0,01347511 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 3,713E-03 0,01345482 ! response to UV-B GO:0010224 16 8 0,000 3,713E-03 0,01343458 ! protein targeting to vacuole GO:0006623 12 8 0,000 3,713E-03 0,01341441 ! protein retention in ER lumen GO:0006621 14 8 0,000 3,713E-03 0,0133943 ! intermediate filament organization GO:0045109 12 8 0,000 3,713E-03 0,01337425 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 3,713E-03 0,01335426 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 3,713E-03 0,01333432 ! cellular extravasation GO:0045123 12 8 0,000 3,713E-03 0,01331445 ! cardiac muscle cell development GO:0055013 13 8 0,000 3,713E-03 0,01329464 ! regulation of circadian rhythm GO:0042752 16 8 0,000 3,713E-03 0,01327488 ! response to antibiotic GO:0046677 11 8 0,000 3,713E-03 0,01325519 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 3,713E-03 0,01323555 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 3,713E-03 0,01321597 ! DNA topological change GO:0006265 12 8 0,000 3,713E-03 0,01319645 ! response to tropane GO:0014073 15 8 0,000 3,713E-03 0,01317699 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 3,713E-03 0,01315758 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 3,713E-03 0,01313823 ! melanosome transport GO:0032402 13 8 0,000 3,713E-03 0,01311894 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 0,000 3,713E-03 0,0130997 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 3,713E-03 0,01308052 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 3,713E-03 0,0130614 ! mast cell activation GO:0045576 14 8 0,000 3,713E-03 0,01304233 ! multicellular organismal aging GO:0010259 18 8 0,000 3,713E-03 0,01302332 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 3,713E-03 0,01300436 ! dendrite morphogenesis GO:0048813 13 8 0,000 3,713E-03 0,01298546 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 3,713E-03 0,01296661 ! nucleosome disassembly GO:0006337 14 8 0,000 3,713E-03 0,01294782 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 3,713E-03 0,01292908 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 3,713E-03 0,0129104 ! leukocyte activation during immune response GO:0002366 13 8 0,000 3,713E-03 0,01289177 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 3,713E-03 0,0128732 ! establishment of chromosome localization GO:0051303 12 8 0,000 3,713E-03 0,01285467 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 3,713E-03 0,0128362 ! intracellular lipid transport GO:0032365 13 8 0,000 3,713E-03 0,01281779 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 3,713E-03 0,01279942 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 3,713E-03 0,01278111 ! regulation of macrophage activation GO:0043030 15 8 0,000 3,713E-03 0,01276285 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 3,713E-03 0,01274465 ! positive regulation of epidermis development GO:0045684 13 8 0,000 3,713E-03 0,01272649 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 3,713E-03 0,01270839 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 3,713E-03 0,01269034 ! hormone catabolic process GO:0042447 17 8 0,000 3,713E-03 0,01267234 ! positive regulation of glucose import GO:0046326 8 8 0,000 3,713E-03 0,01265439 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 3,713E-03 0,01263649 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 3,713E-03 0,01261864 ! ATP catabolic process GO:0006200 11 8 0,000 3,713E-03 0,01260084 ! blastocyst growth GO:0001832 19 8 0,000 3,713E-03 0,01258309 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 3,713E-03 0,0125654 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 3,713E-03 0,01254775 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 3,713E-03 0,01253015 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 3,713E-03 0,0125126 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 3,713E-03 0,0124951 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 3,713E-03 0,01247765 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 3,713E-03 0,01246025 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 3,713E-03 0,01244289 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 3,713E-03 0,01242559 ! amino sugar catabolic process GO:0046348 10 8 0,000 3,713E-03 0,01240833 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 3,713E-03 0,01239112 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 3,713E-03 0,01237396 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 3,713E-03 0,01235684 ! behavioral response to nicotine GO:0035095 12 8 0,000 3,713E-03 0,01233978 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 3,713E-03 0,01232276 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 3,713E-03 0,01230578 ! NAD biosynthetic process GO:0009435 13 8 0,000 3,713E-03 0,01228885 ! regulation of developmental growth GO:0048638 15 9 0,000 4,176E-03 0,01380299 ! axon extension GO:0048675 15 9 0,000 4,176E-03 0,01378406 ! autophagic vacuole formation GO:0000045 15 9 0,000 4,176E-03 0,01376518 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 4,176E-03 0,01374635 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 4,176E-03 0,01372757 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 4,176E-03 0,01370884 ! pentose-phosphate shunt GO:0006098 16 9 0,000 4,176E-03 0,01369016 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 4,176E-03 0,01367154 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 4,176E-03 0,01365296 ! cell proliferation in forebrain GO:0021846 15 9 0,000 4,176E-03 0,01363443 ! phosphate transport GO:0006817 19 9 0,000 4,176E-03 0,01361596 ! reproductive behavior GO:0019098 19 9 0,000 4,176E-03 0,01359754 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 4,176E-03 0,01357916 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 4,176E-03 0,01356083 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 4,176E-03 0,01354256 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 4,176E-03 0,01352433 ! GTP metabolic process GO:0046039 9 9 0,000 4,176E-03 0,01350615 ! RNA methylation GO:0001510 15 9 0,000 4,176E-03 0,01348802 ! elastic fiber assembly GO:0048251 15 9 0,000 4,176E-03 0,01346994 ! induction of positive chemotaxis GO:0050930 15 9 0,000 4,176E-03 0,01345191 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 4,176E-03 0,01343393 ! artery development GO:0060840 24 9 0,000 4,176E-03 0,01341599 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 4,176E-03 0,0133981 ! regulation of glycolysis GO:0006110 21 9 0,000 4,176E-03 0,01338026 ! cerebral cortex cell migration GO:0021795 15 9 0,000 4,176E-03 0,01336247 ! keratinocyte proliferation GO:0043616 14 9 0,000 4,176E-03 0,01334473 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 4,176E-03 0,01332703 ! chemosensory behavior GO:0007635 20 9 0,000 4,176E-03 0,01330938 ! microtubule bundle formation GO:0001578 21 9 0,000 4,176E-03 0,01329177 ! middle ear morphogenesis GO:0042474 14 9 0,000 4,176E-03 0,01327421 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 4,176E-03 0,0132567 ! leukocyte degranulation GO:0043299 16 9 0,000 4,176E-03 0,01323923 ! bile acid and bile salt transport GO:0015721 13 9 0,000 4,176E-03 0,01322181 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 4,176E-03 0,01320444 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 4,176E-03 0,01318711 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 4,176E-03 0,01316983 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 4,176E-03 0,01315259 ! protein targeting to ER GO:0045047 22 9 0,000 4,176E-03 0,0131354 ! ceramide biosynthetic process GO:0046513 19 9 0,000 4,176E-03 0,01311825 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 4,176E-03 0,01310115 ! T cell selection GO:0045058 23 9 0,000 4,176E-03 0,01308409 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 4,176E-03 0,01306707 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 4,176E-03 0,0130501 ! phosphagen metabolic process GO:0006599 12 9 0,000 4,176E-03 0,01303318 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 4,176E-03 0,01301629 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 4,176E-03 0,01299945 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 4,176E-03 0,01298266 ! regulation of type I interferon production GO:0032479 12 9 0,000 4,176E-03 0,01296591 ! mannose metabolic process GO:0006013 13 9 0,000 4,176E-03 0,0129492 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 4,176E-03 0,01293253 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 4,176E-03 0,01291591 ! Rac protein signal transduction GO:0016601 17 9 0,000 4,176E-03 0,01289933 ! receptor clustering GO:0043113 18 9 0,000 4,176E-03 0,01288279 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 4,176E-03 0,0128663 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 4,176E-03 0,01284984 ! ruffle organization GO:0031529 15 9 0,000 4,176E-03 0,01283343 ! retinol metabolic process GO:0042572 18 9 0,000 4,176E-03 0,01281706 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 4,176E-03 0,01280074 ! behavioral fear response GO:0001662 22 9 0,000 4,176E-03 0,01278445 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 4,176E-03 0,01276821 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 4,176E-03 0,012752 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 4,176E-03 0,01273584 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 4,176E-03 0,01271972 ! protein heterooligomerization GO:0051291 16 9 0,000 4,176E-03 0,01270364 ! oligodendrocyte development GO:0014003 10 9 0,000 4,176E-03 0,0126876 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 4,176E-03 0,0126716 ! segment specification GO:0007379 13 9 0,000 4,176E-03 0,01265564 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 4,176E-03 0,01263972 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 4,176E-03 0,01262384 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 4,176E-03 0,012608 ! response to amine stimulus GO:0014075 13 9 0,000 4,176E-03 0,0125922 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 4,176E-03 0,01257644 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 4,176E-03 0,01256072 ! erythrocyte development GO:0048821 15 9 0,000 4,176E-03 0,01254504 ! gas homeostasis GO:0033483 16 9 0,000 4,176E-03 0,0125294 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 4,176E-03 0,0125138 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 4,176E-03 0,01249823 ! renal water homeostasis GO:0003091 14 9 0,000 4,176E-03 0,01248271 ! postreplication repair GO:0006301 22 9 0,000 4,176E-03 0,01246722 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 4,176E-03 0,01245177 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 4,176E-03 0,01243636 ! icosanoid secretion GO:0032309 15 9 0,000 4,176E-03 0,01242099 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 4,176E-03 0,01240565 ! cerebellum morphogenesis GO:0021587 14 9 0,000 4,176E-03 0,01239036 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 4,176E-03 0,0123751 ! regulation of cell division GO:0051302 15 9 0,000 4,176E-03 0,01235988 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 4,176E-03 0,01234469 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 4,176E-03 0,01232954 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 4,176E-03 0,01231443 ! sterol catabolic process GO:0016127 11 9 0,000 4,176E-03 0,01229936 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 4,176E-03 0,01228433 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 4,176E-03 0,01226933 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 4,176E-03 0,01225436 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 4,176E-03 0,01223944 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 4,176E-03 0,01222455 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 4,176E-03 0,01220969 ! musculoskeletal movement GO:0050881 14 9 0,000 4,176E-03 0,01219488 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 4,176E-03 0,0121801 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 4,176E-03 0,01216535 ! regulation of synaptogenesis GO:0051963 15 9 0,000 4,176E-03 0,01215064 ! purine base metabolic process GO:0006144 21 9 0,000 4,176E-03 0,01213596 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 4,176E-03 0,01212133 ! pigment granule transport GO:0051904 17 9 0,000 4,176E-03 0,01210672 ! regulation of fibrinolysis GO:0051917 16 9 0,000 4,176E-03 0,01209215 ! regulation of telomere maintenance GO:0032204 14 9 0,000 4,176E-03 0,01207762 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 4,176E-03 0,01206312 ! regulation of muscle adaptation GO:0043502 14 9 0,000 4,176E-03 0,01204866 ! regulation of amino acid transport GO:0051955 11 9 0,000 4,176E-03 0,01203423 ! mitochondrion localization GO:0051646 15 9 0,000 4,176E-03 0,01201983 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 4,64E-03 0,01333653 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 4,64E-03 0,01332062 ! negative regulation of blood pressure GO:0045776 26 10 0,000 4,64E-03 0,01330474 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 4,64E-03 0,0132889 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 4,64E-03 0,0132731 ! regulation of phosphatase activity GO:0010921 28 10 0,000 4,64E-03 0,01325734 ! synapsis GO:0007129 13 10 0,000 4,64E-03 0,01324161 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 4,64E-03 0,01322592 ! N-glycan processing GO:0006491 20 10 0,000 4,64E-03 0,01321027 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 4,64E-03 0,01319466 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 4,64E-03 0,01317908 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 4,64E-03 0,01316354 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 4,64E-03 0,01314803 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 4,64E-03 0,01313256 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 4,64E-03 0,01311713 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 4,64E-03 0,01310174 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 4,64E-03 0,01308638 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 4,64E-03 0,01307105 ! androgen metabolic process GO:0008209 17 10 0,000 4,64E-03 0,01305576 ! phospholipid efflux GO:0033700 16 10 0,000 4,64E-03 0,01304051 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 4,64E-03 0,0130253 ! positive regulation of heart contraction GO:0045823 16 10 0,000 4,64E-03 0,01301011 ! lung alveolus development GO:0048286 26 10 0,000 4,64E-03 0,01299497 ! pathogenesis GO:0009405 13 10 0,000 4,64E-03 0,01297986 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 4,64E-03 0,01296478 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 4,64E-03 0,01294974 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 4,64E-03 0,01293474 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 4,64E-03 0,01291977 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 4,64E-03 0,01290483 ! endoderm development GO:0007492 16 10 0,000 4,64E-03 0,01288993 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 4,64E-03 0,01287506 ! arginine catabolic process GO:0006527 13 10 0,000 4,64E-03 0,01286023 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 4,64E-03 0,01284543 ! proline metabolic process GO:0006560 13 10 0,000 4,64E-03 0,01283066 ! glucan biosynthetic process GO:0009250 14 10 0,000 4,64E-03 0,01281593 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 4,64E-03 0,01280124 ! polyamine biosynthetic process GO:0006596 12 10 0,000 4,64E-03 0,01278657 ! V(D)J recombination GO:0033151 28 10 0,000 4,64E-03 0,01277194 ! reverse cholesterol transport GO:0043691 16 10 0,000 4,64E-03 0,01275735 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 4,64E-03 0,01274278 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 4,64E-03 0,01272825 ! B cell proliferation GO:0042100 18 10 0,000 4,64E-03 0,01271376 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 4,64E-03 0,01269929 ! regulation of sodium ion transport GO:0002028 21 10 0,000 4,64E-03 0,01268486 ! multicellular organism growth GO:0035264 18 10 0,000 4,64E-03 0,01267046 ! phagocytosis, engulfment GO:0006911 28 10 0,000 4,64E-03 0,0126561 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 4,64E-03 0,01264176 ! epithelial cell development GO:0002064 20 10 0,000 4,64E-03 0,01262746 ! lens development in camera-type eye GO:0002088 16 10 0,000 4,64E-03 0,0126132 ! retinoic acid metabolic process GO:0042573 14 10 0,000 4,64E-03 0,01259896 ! macroautophagy GO:0016236 17 10 0,000 4,64E-03 0,01258476 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 4,64E-03 0,01257058 ! positive regulation of translational initiation GO:0045948 11 10 0,000 4,64E-03 0,01255644 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 4,64E-03 0,01254234 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 4,64E-03 0,01252826 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 4,64E-03 0,01251421 ! copper ion homeostasis GO:0055070 13 10 0,000 4,64E-03 0,0125002 ! regulation of bone resorption GO:0045124 25 10 0,000 4,64E-03 0,01248622 ! regulation of gliogenesis GO:0014013 23 10 0,000 4,64E-03 0,01247227 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 4,64E-03 0,01245835 ! alpha-beta T cell activation GO:0046631 23 10 0,000 4,64E-03 0,01244446 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 4,64E-03 0,0124306 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 4,64E-03 0,01241677 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 4,64E-03 0,01240298 ! blastoderm segmentation GO:0007350 18 10 0,000 4,64E-03 0,01238921 ! response to dsRNA GO:0043331 20 10 0,000 4,64E-03 0,01237547 ! DNA ligation GO:0006266 19 10 0,000 4,64E-03 0,01236177 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 4,64E-03 0,0123481 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 4,64E-03 0,01233445 ! melanosome localization GO:0032400 16 10 0,000 4,64E-03 0,01232084 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 4,64E-03 0,01230725 ! regulation of B cell differentiation GO:0045577 19 10 0,000 4,64E-03 0,0122937 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 4,64E-03 0,01228017 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 4,64E-03 0,01226668 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 4,64E-03 0,01225321 ! mRNA cleavage GO:0006379 17 10 0,000 4,64E-03 0,01223978 ! protein sumoylation GO:0016925 15 10 0,000 4,64E-03 0,01222637 ! hindbrain morphogenesis GO:0021575 19 10 0,000 4,64E-03 0,012213 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 4,64E-03 0,01219965 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 4,64E-03 0,01218633 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 4,64E-03 0,01217304 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 4,64E-03 0,01215978 ! salivary gland development GO:0007431 27 10 0,000 4,64E-03 0,01214655 ! prophase GO:0051324 15 10 0,000 4,64E-03 0,01213335 ! negative regulation of neurological system process GO:0031645 19 10 0,000 4,64E-03 0,01212017 ! apical protein localization GO:0045176 15 10 0,000 4,64E-03 0,01210703 ! ubiquinone metabolic process GO:0006743 15 10 0,000 4,64E-03 0,01209391 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 4,64E-03 0,01208082 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 4,64E-03 0,01206776 ! midbrain development GO:0030901 13 10 0,000 4,64E-03 0,01205473 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 4,64E-03 0,01204172 ! methionine biosynthetic process GO:0009086 19 10 0,000 4,64E-03 0,01202875 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 4,64E-03 0,0120158 ! quaternary ammonium group transport GO:0015697 21 10 0,000 4,64E-03 0,01200288 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 4,64E-03 0,01198999 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 4,64E-03 0,01197712 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 4,64E-03 0,01196429 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 4,64E-03 0,01195148 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 4,64E-03 0,01193869 ! oocyte development GO:0048599 17 10 0,000 4,64E-03 0,01192594 ! establishment of pigment granule localization GO:0051905 18 10 0,000 4,64E-03 0,01191321 ! blastocyst formation GO:0001825 17 10 0,000 4,64E-03 0,01190051 ! cerebellar cortex development GO:0021695 15 10 0,000 4,64E-03 0,01188784 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 4,64E-03 0,01187519 ! activation of innate immune response GO:0002218 12 10 0,000 4,64E-03 0,01186257 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 4,64E-03 0,01184998 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 4,64E-03 0,01183741 ! response to nicotine GO:0035094 20 10 0,000 4,64E-03 0,01182487 ! establishment of cell polarity GO:0030010 16 10 0,000 4,64E-03 0,01181236 ! negative regulation of immune effector process GO:0002698 20 10 0,000 4,64E-03 0,01179987 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 4,64E-03 0,01178741 ! localization within membrane GO:0051668 20 10 0,000 4,64E-03 0,01177498 ! negative regulation of muscle development GO:0048635 20 11 0,000 5,102E-03 0,01293604 ! respiratory burst GO:0045730 17 11 0,000 5,102E-03 0,01292242 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 5,102E-03 0,01290883 ! neuron fate specification GO:0048665 17 11 0,000 5,102E-03 0,01289527 ! telencephalon cell migration GO:0022029 20 11 0,000 5,102E-03 0,01288174 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 5,102E-03 0,01286824 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 5,102E-03 0,01285476 ! thyroid gland development GO:0030878 26 11 0,000 5,102E-03 0,01284132 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 5,102E-03 0,0128279 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 5,102E-03 0,01281451 ! Golgi vesicle budding GO:0048194 22 11 0,000 5,102E-03 0,01280114 ! response to pain GO:0048265 24 11 0,000 5,102E-03 0,01278781 ! detection of mechanical stimulus GO:0050982 22 11 0,000 5,102E-03 0,0127745 ! T cell proliferation GO:0042098 26 11 0,000 5,102E-03 0,01276122 ! blood vessel remodeling GO:0001974 29 11 0,000 5,102E-03 0,01274797 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 5,102E-03 0,01273475 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 5,102E-03 0,01272155 ! bone resorption GO:0045453 16 11 0,000 5,102E-03 0,01270838 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 5,102E-03 0,01269524 ! ventral spinal cord development GO:0021517 21 11 0,000 5,102E-03 0,01268213 ! negative regulation of proteolysis GO:0045861 25 11 0,000 5,102E-03 0,01266904 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 5,102E-03 0,01265598 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 5,102E-03 0,01264294 ! melanocyte differentiation GO:0030318 21 11 0,000 5,102E-03 0,01262994 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 5,102E-03 0,01261696 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 5,102E-03 0,012604 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 5,102E-03 0,01259107 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 5,102E-03 0,01257817 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 5,102E-03 0,0125653 ! lipid digestion GO:0044241 18 11 0,000 5,102E-03 0,01255245 ! substrate-bound cell migration GO:0006929 13 11 0,000 5,102E-03 0,01253963 ! UV protection GO:0009650 19 11 0,000 5,102E-03 0,01252683 ! adult heart development GO:0007512 14 11 0,000 5,102E-03 0,01251406 ! chondrocyte differentiation GO:0002062 24 11 0,000 5,102E-03 0,01250132 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 5,102E-03 0,0124886 ! temperature homeostasis GO:0001659 17 11 0,000 5,102E-03 0,01247591 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 5,102E-03 0,01246325 ! negative regulation of ossification GO:0030279 26 11 0,000 5,102E-03 0,01245061 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 5,102E-03 0,01243799 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 5,102E-03 0,0124254 ! regulation of organ growth GO:0046620 13 11 0,000 5,102E-03 0,01241284 ! pigment granule localization GO:0051875 20 11 0,000 5,102E-03 0,0124003 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 5,102E-03 0,01238779 ! vasoconstriction GO:0042310 18 11 0,000 5,102E-03 0,0123753 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 5,102E-03 0,01236284 ! embryonic axis specification GO:0000578 18 11 0,000 5,102E-03 0,0123504 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 5,102E-03 0,01233799 ! snRNA metabolic process GO:0016073 24 11 0,000 5,102E-03 0,0123256 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 5,102E-03 0,01231324 ! nitric oxide metabolic process GO:0046209 15 11 0,000 5,102E-03 0,0123009 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 5,102E-03 0,01228859 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 5,102E-03 0,0122763 ! zymogen activation GO:0031638 15 11 0,000 5,102E-03 0,01226403 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 5,102E-03 0,01225179 ! neuroblast proliferation GO:0007405 24 11 0,000 5,102E-03 0,01223958 ! nucleosome positioning GO:0016584 15 11 0,000 5,102E-03 0,01222739 ! regulation of isotype switching GO:0045191 22 11 0,000 5,102E-03 0,01221522 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 5,102E-03 0,01220308 ! glutathione biosynthetic process GO:0006750 13 11 0,000 5,102E-03 0,01219096 ! regulation of leukocyte migration GO:0002685 26 11 0,000 5,102E-03 0,01217887 ! acid secretion GO:0046717 18 11 0,000 5,102E-03 0,0121668 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 5,102E-03 0,01215475 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 5,102E-03 0,01214273 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 5,102E-03 0,01213073 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 5,102E-03 0,01211875 ! oocyte differentiation GO:0009994 18 11 0,000 5,102E-03 0,0121068 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 5,102E-03 0,01209487 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 5,102E-03 0,01208297 ! cholesterol efflux GO:0033344 19 11 0,000 5,102E-03 0,01207109 ! anterior/posterior axis specification GO:0009948 18 11 0,000 5,102E-03 0,01205923 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 5,102E-03 0,0120474 ! negative regulation of glucose import GO:0046325 17 11 0,000 5,102E-03 0,01203559 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 5,102E-03 0,0120238 ! embryonic gut development GO:0048566 15 11 0,000 5,102E-03 0,01201203 ! regulation of organic acid transport GO:0032890 18 11 0,000 5,102E-03 0,01200029 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 5,102E-03 0,01198857 ! cardiac cell differentiation GO:0035051 31 11 0,000 5,102E-03 0,01197688 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 5,102E-03 0,0119652 ! defense response to fungus GO:0050832 13 11 0,000 5,102E-03 0,01195355 ! developmental induction GO:0031128 19 11 0,000 5,102E-03 0,01194192 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 5,102E-03 0,01193032 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 5,102E-03 0,01191874 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 5,102E-03 0,01190717 ! sequestering of metal ion GO:0051238 14 11 0,000 5,102E-03 0,01189564 ! lamellipodium assembly GO:0030032 20 11 0,000 5,102E-03 0,01188412 ! regulation of embryonic development GO:0045995 27 11 0,000 5,102E-03 0,01187263 ! nucleus localization GO:0051647 19 11 0,000 5,102E-03 0,01186116 ! regulation of synapse organization GO:0050807 17 11 0,000 5,102E-03 0,01184971 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 5,565E-03 0,0129117 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 5,565E-03 0,01289926 ! positive regulation of blood pressure GO:0045777 17 12 0,000 5,565E-03 0,01288685 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 5,565E-03 0,01287446 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 5,565E-03 0,01286209 ! virus-host interaction GO:0019048 29 12 0,000 5,565E-03 0,01284975 ! regulation of B cell proliferation GO:0030888 20 12 0,000 5,565E-03 0,01283743 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 5,565E-03 0,01282513 ! cartilage condensation GO:0001502 20 12 0,000 5,565E-03 0,01281286 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 5,565E-03 0,01280061 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 5,565E-03 0,01278838 ! protein complex disassembly GO:0043241 27 12 0,000 5,565E-03 0,01277618 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 5,565E-03 0,012764 ! regulation of cell projection assembly GO:0060491 30 12 0,000 5,565E-03 0,01275184 ! hippocampus development GO:0021766 26 12 0,000 5,565E-03 0,01273971 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 5,565E-03 0,0127276 ! cytokine biosynthetic process GO:0042089 21 12 0,000 5,565E-03 0,01271551 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 5,565E-03 0,01270345 ! positive regulation of cell growth GO:0030307 22 12 0,000 5,565E-03 0,01269141 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 5,565E-03 0,01267939 ! regulation of exit from mitosis GO:0007096 17 12 0,000 5,565E-03 0,01266739 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 5,565E-03 0,01265542 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 5,565E-03 0,01264347 ! drug transport GO:0015893 16 12 0,000 5,565E-03 0,01263154 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 5,565E-03 0,01261964 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 5,565E-03 0,01260775 ! tyrosine metabolic process GO:0006570 16 12 0,000 5,565E-03 0,01259589 ! polyamine metabolic process GO:0006595 17 12 0,000 5,565E-03 0,01258406 ! focal adhesion formation GO:0048041 35 12 0,000 5,565E-03 0,01257224 ! mitotic spindle organization GO:0007052 21 12 0,000 5,565E-03 0,01256045 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 5,565E-03 0,01254867 ! forebrain cell migration GO:0021885 21 12 0,000 5,565E-03 0,01253692 ! asymmetric protein localization GO:0008105 20 12 0,000 5,565E-03 0,0125252 ! membrane protein proteolysis GO:0033619 25 12 0,000 5,565E-03 0,01251349 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 5,565E-03 0,01250181 ! entry into host cell GO:0030260 32 12 0,000 5,565E-03 0,01249014 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 5,565E-03 0,0124785 ! monoamine transport GO:0015844 18 12 0,000 5,565E-03 0,01246689 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 5,565E-03 0,01245529 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 5,565E-03 0,01244371 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 5,565E-03 0,01243216 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 5,565E-03 0,01242063 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 5,565E-03 0,01240912 ! protein targeting to peroxisome GO:0006625 23 12 0,000 5,565E-03 0,01239763 ! protein homotetramerization GO:0051289 21 12 0,000 5,565E-03 0,01238616 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 5,565E-03 0,01237471 ! regulation of phagocytosis GO:0050764 16 12 0,000 5,565E-03 0,01236328 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 5,565E-03 0,01235188 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 5,565E-03 0,01234049 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 5,565E-03 0,01232913 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 5,565E-03 0,01231779 ! cranial nerve development GO:0021545 20 12 0,000 5,565E-03 0,01230647 ! fucose catabolic process GO:0019317 22 12 0,000 5,565E-03 0,01229517 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 5,565E-03 0,01228389 ! histone acetylation GO:0016573 26 12 0,000 5,565E-03 0,01227263 ! histone methylation GO:0016571 26 12 0,000 5,565E-03 0,01226139 ! mRNA polyadenylation GO:0006378 23 12 0,000 5,565E-03 0,01225017 ! autonomic nervous system development GO:0048483 24 12 0,000 5,565E-03 0,01223897 ! gland morphogenesis GO:0022612 29 12 0,000 5,565E-03 0,01222779 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 5,565E-03 0,01221664 ! peptidyl-lysine modification GO:0018205 21 12 0,000 5,565E-03 0,0122055 ! T cell homeostasis GO:0043029 25 12 0,000 5,565E-03 0,01219439 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 5,565E-03 0,01218329 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 5,565E-03 0,01217221 ! spleen development GO:0048536 22 12 0,000 5,565E-03 0,01216116 ! digestive tract morphogenesis GO:0048546 26 12 0,000 5,565E-03 0,01215012 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 5,565E-03 0,01213911 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 5,565E-03 0,01212811 ! regulation of RNA splicing GO:0043484 20 12 0,000 5,565E-03 0,01211714 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 5,565E-03 0,01210618 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 5,565E-03 0,01209524 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 5,565E-03 0,01208433 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 5,565E-03 0,01207343 ! response to cold GO:0009409 17 12 0,000 5,565E-03 0,01206255 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 5,565E-03 0,0120517 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 5,565E-03 0,01204086 ! cGMP metabolic process GO:0046068 18 13 0,000 6,027E-03 0,01302973 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 6,027E-03 0,01301804 ! regulation of chemokine production GO:0032642 18 13 0,000 6,027E-03 0,01300636 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 6,027E-03 0,01299471 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 6,027E-03 0,01298307 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 6,027E-03 0,01297146 ! lipid localization GO:0010876 28 13 0,000 6,027E-03 0,01295987 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 6,027E-03 0,0129483 ! organelle fusion GO:0048284 32 13 0,000 6,027E-03 0,01293675 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 6,027E-03 0,01292522 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 6,027E-03 0,01291371 ! pseudouridine synthesis GO:0001522 17 13 0,000 6,027E-03 0,01290222 ! endocrine pancreas development GO:0031018 22 13 0,000 6,027E-03 0,01289075 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 6,027E-03 0,0128793 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 6,027E-03 0,01286787 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 6,027E-03 0,01285647 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 6,027E-03 0,01284508 ! methionine metabolic process GO:0006555 27 13 0,000 6,027E-03 0,01283371 ! plasma membrane organization GO:0007009 24 13 0,000 6,027E-03 0,01282236 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 6,027E-03 0,01281104 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 6,027E-03 0,01279973 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 6,027E-03 0,01278844 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 6,027E-03 0,01277717 ! cell-cell junction assembly GO:0007043 27 13 0,000 6,027E-03 0,01276593 ! response to X-ray GO:0010165 25 13 0,000 6,027E-03 0,0127547 ! cytokine metabolic process GO:0042107 22 13 0,000 6,027E-03 0,01274349 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 6,027E-03 0,0127323 ! exocrine system development GO:0035272 32 13 0,000 6,027E-03 0,01272113 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 6,027E-03 0,01270998 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 6,027E-03 0,01269886 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 6,027E-03 0,01268775 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 6,027E-03 0,01267665 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 6,027E-03 0,01266558 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 6,027E-03 0,01265453 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 6,027E-03 0,0126435 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 6,027E-03 0,01263248 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 6,027E-03 0,01262149 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 6,027E-03 0,01261052 ! regulation of cellular pH GO:0030641 22 13 0,000 6,027E-03 0,01259956 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 6,027E-03 0,01258862 ! ribosome assembly GO:0042255 17 13 0,000 6,027E-03 0,0125777 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 6,027E-03 0,0125668 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 6,027E-03 0,01255592 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 6,027E-03 0,01254506 ! chromatin silencing GO:0006342 26 13 0,000 6,027E-03 0,01253422 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 6,027E-03 0,0125234 ! regulation of epidermis development GO:0045682 19 13 0,000 6,027E-03 0,01251259 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 6,027E-03 0,0125018 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 6,027E-03 0,01249104 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 6,027E-03 0,01248029 ! regulation of mRNA stability GO:0043488 31 13 0,000 6,027E-03 0,01246956 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 6,027E-03 0,01245884 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 6,027E-03 0,01244815 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 6,027E-03 0,01243747 ! mRNA 3'-end processing GO:0031124 24 13 0,000 6,027E-03 0,01242681 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 6,027E-03 0,01241618 ! embryonic placenta development GO:0001892 23 13 0,000 6,027E-03 0,01240555 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 6,027E-03 0,01239495 ! insulin secretion GO:0030073 23 13 0,000 6,027E-03 0,01238437 ! actin filament polymerization GO:0030041 24 13 0,000 6,027E-03 0,0123738 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 6,027E-03 0,01236325 ! acrosome reaction GO:0007340 18 13 0,000 6,027E-03 0,01235272 ! rRNA transcription GO:0009303 25 14 0,000 6,49E-03 0,01328874 ! lactation GO:0007595 26 14 0,000 6,49E-03 0,01327744 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 6,49E-03 0,01326616 ! reproductive cellular process GO:0048610 20 14 0,000 6,49E-03 0,0132549 ! tRNA modification GO:0006400 20 14 0,000 6,49E-03 0,01324366 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 6,49E-03 0,01323243 ! regulation of S phase GO:0033261 23 14 0,000 6,49E-03 0,01322123 ! water transport GO:0006833 21 14 0,000 6,49E-03 0,01321004 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 6,49E-03 0,01319888 ! non-recombinational repair GO:0000726 25 14 0,000 6,49E-03 0,01318773 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 6,49E-03 0,0131766 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 6,49E-03 0,01316549 ! retina development in camera-type eye GO:0060041 27 14 0,000 6,49E-03 0,0131544 ! hair follicle morphogenesis GO:0031069 26 14 0,000 6,49E-03 0,01314332 ! RNA polyadenylation GO:0043631 30 14 0,000 6,49E-03 0,01313227 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 6,49E-03 0,01312123 ! palate development GO:0060021 31 14 0,000 6,49E-03 0,01311022 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 6,49E-03 0,01309922 ! regulated secretory pathway GO:0045055 23 14 0,000 6,49E-03 0,01308824 ! regulation of mRNA processing GO:0050684 24 14 0,000 6,49E-03 0,01307728 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 6,49E-03 0,01306633 ! arginine metabolic process GO:0006525 17 14 0,000 6,49E-03 0,01305541 ! regulation of heart rate GO:0002027 24 14 0,000 6,49E-03 0,0130445 ! organic alcohol transport GO:0015850 29 14 0,000 6,49E-03 0,01303361 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 6,49E-03 0,01302274 ! negative regulation of caspase activity GO:0043154 22 14 0,000 6,49E-03 0,01301189 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 6,49E-03 0,01300106 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 6,49E-03 0,01299024 ! neutral amino acid transport GO:0015804 26 14 0,000 6,49E-03 0,01297944 ! L-amino acid transport GO:0015807 30 14 0,000 6,49E-03 0,01296866 ! bone mineralization GO:0030282 17 14 0,000 6,49E-03 0,0129579 ! stem cell development GO:0048864 43 14 0,000 6,49E-03 0,01294716 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 6,49E-03 0,01293643 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 6,49E-03 0,01292572 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 6,49E-03 0,01291503 ! cerebellum development GO:0021549 21 14 0,000 6,49E-03 0,01290435 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 6,49E-03 0,0128937 ! negative regulation of protein secretion GO:0050709 28 14 0,000 6,49E-03 0,01288306 ! response to gamma radiation GO:0010332 28 14 0,000 6,49E-03 0,01287244 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 6,49E-03 0,01286184 ! cofactor transport GO:0051181 26 14 0,000 6,49E-03 0,01285125 ! NADP metabolic process GO:0006739 24 14 0,000 6,49E-03 0,01284068 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 6,49E-03 0,01283013 ! protein-chromophore linkage GO:0018298 19 14 0,000 6,49E-03 0,0128196 ! intestinal absorption GO:0050892 25 14 0,000 6,49E-03 0,01280908 ! cAMP biosynthetic process GO:0006171 23 14 0,000 6,49E-03 0,01279858 ! oxygen transport GO:0015671 21 14 0,000 6,49E-03 0,0127881 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 6,49E-03 0,01277763 ! male genitalia development GO:0030539 24 14 0,000 6,49E-03 0,01276719 ! regulation of RNA stability GO:0043487 32 14 0,000 6,49E-03 0,01275676 ! regulation of axon extension GO:0030516 37 14 0,000 6,49E-03 0,01274634 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 6,49E-03 0,01273595 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 6,49E-03 0,01272557 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 6,952E-03 0,01362049 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 6,952E-03 0,01360941 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 6,952E-03 0,01359835 ! superoxide anion generation GO:0042554 20 15 0,000 6,952E-03 0,0135873 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 6,952E-03 0,01357627 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 6,952E-03 0,01356526 ! phospholipid catabolic process GO:0009395 22 15 0,000 6,952E-03 0,01355427 ! copper ion transport GO:0006825 20 15 0,000 6,952E-03 0,01354329 ! heterophilic cell adhesion GO:0007157 39 15 0,000 6,952E-03 0,01353233 ! cardiac muscle contraction GO:0060048 26 15 0,000 6,952E-03 0,0135214 ! sulfate transport GO:0008272 23 15 0,000 6,952E-03 0,01351047 ! response to cAMP GO:0051591 22 15 0,000 6,952E-03 0,01349957 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 6,952E-03 0,01348868 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 6,952E-03 0,01347781 ! ciliary or flagellar motility GO:0001539 20 15 0,000 6,952E-03 0,01346696 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 6,952E-03 0,01345613 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 6,952E-03 0,01344531 ! response to hexose stimulus GO:0009746 22 15 0,000 6,952E-03 0,01343451 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 6,952E-03 0,01342373 ! glycoprotein catabolic process GO:0006516 26 15 0,000 6,952E-03 0,01341296 ! pituitary gland development GO:0021983 29 15 0,000 6,952E-03 0,01340222 ! vesicle coating GO:0006901 33 15 0,000 6,952E-03 0,01339149 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 6,952E-03 0,01338077 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 6,952E-03 0,01337008 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 6,952E-03 0,0133594 ! regulation of exocytosis GO:0017157 22 15 0,000 6,952E-03 0,01334874 ! G1/S transition checkpoint GO:0031575 40 15 0,000 6,952E-03 0,01333809 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 6,952E-03 0,01332746 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 6,952E-03 0,01331685 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 6,952E-03 0,01330626 ! regulation of vasodilation GO:0042312 26 15 0,000 6,952E-03 0,01329568 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 6,952E-03 0,01328512 ! histone deacetylation GO:0016575 20 15 0,000 6,952E-03 0,01327458 ! mRNA splice site selection GO:0006376 38 15 0,000 6,952E-03 0,01326405 ! tissue regeneration GO:0042246 26 15 0,000 6,952E-03 0,01325354 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 6,952E-03 0,01324305 ! water homeostasis GO:0030104 27 15 0,000 6,952E-03 0,01323257 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 6,952E-03 0,01322211 ! muscle maintenance GO:0046716 26 15 0,000 6,952E-03 0,01321166 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 6,952E-03 0,01320124 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 6,952E-03 0,01319082 ! regulation of ATPase activity GO:0043462 21 15 0,000 6,952E-03 0,01318043 ! dopamine metabolic process GO:0042417 35 15 0,000 6,952E-03 0,01317005 ! heme biosynthetic process GO:0006783 29 15 0,000 6,952E-03 0,01315969 ! cell killing GO:0001906 29 15 0,000 6,952E-03 0,01314934 ! lymphocyte homeostasis GO:0002260 30 15 0,000 6,952E-03 0,01313901 ! detection of bacterium GO:0016045 18 15 0,000 6,952E-03 0,0131287 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 6,952E-03 0,0131184 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 6,952E-03 0,01310812 ! L-fucose metabolic process GO:0042354 30 15 0,000 6,952E-03 0,01309786 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 6,952E-03 0,01308761 ! peptide hormone processing GO:0016486 23 15 0,000 6,952E-03 0,01307738 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 7,414E-03 0,0139353 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 7,414E-03 0,01392442 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 7,414E-03 0,01391356 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 7,414E-03 0,01390271 ! dicarboxylic acid transport GO:0006835 38 16 0,000 7,414E-03 0,01389189 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 7,414E-03 0,01388108 ! bone remodeling GO:0046849 27 16 0,000 7,414E-03 0,01387028 ! filopodium assembly GO:0046847 32 16 0,000 7,414E-03 0,0138595 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 7,414E-03 0,01384874 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 7,414E-03 0,013838 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 7,414E-03 0,01382727 ! positive regulation of ion transport GO:0043270 21 16 0,000 7,414E-03 0,01381656 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 7,414E-03 0,01380587 ! startle response GO:0001964 28 16 0,000 7,414E-03 0,01379519 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 7,414E-03 0,01378453 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 7,414E-03 0,01377389 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 7,414E-03 0,01376326 ! activation of MAPKK activity GO:0000186 35 16 0,000 7,414E-03 0,01375265 ! regulation of defense response to virus GO:0050688 27 16 0,000 7,414E-03 0,01374205 ! protein polyubiquitination GO:0000209 34 16 0,000 7,414E-03 0,01373147 ! glutamate metabolic process GO:0006536 22 16 0,000 7,414E-03 0,01372091 ! complement activation, alternative pathway GO:0006957 18 16 0,000 7,414E-03 0,01371036 ! response to osmotic stress GO:0006970 25 16 0,000 7,414E-03 0,01369983 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 7,414E-03 0,01368932 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 7,414E-03 0,01367882 ! fructose metabolic process GO:0006000 25 16 0,000 7,414E-03 0,01366834 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 7,414E-03 0,01365787 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 7,414E-03 0,01364742 ! intermediate filament-based process GO:0045103 32 16 0,000 7,414E-03 0,01363699 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 7,414E-03 0,01362657 ! negative regulation of immune response GO:0050777 35 16 0,000 7,414E-03 0,01361617 ! axon cargo transport GO:0008088 43 16 0,000 7,414E-03 0,01360578 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 7,414E-03 0,01359541 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 7,414E-03 0,01358506 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 7,414E-03 0,01357472 ! DNA replication initiation GO:0006270 27 16 0,000 7,414E-03 0,0135644 ! neuron recognition GO:0008038 35 16 0,000 7,414E-03 0,01355409 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 7,414E-03 0,0135438 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 7,414E-03 0,01353352 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 7,414E-03 0,01352326 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 7,414E-03 0,01351302 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 7,414E-03 0,01350279 ! sphingolipid catabolic process GO:0030149 27 16 0,000 7,414E-03 0,01349257 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 7,414E-03 0,01348238 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 7,414E-03 0,01347219 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 7,414E-03 0,01346202 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 7,414E-03 0,01345187 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 7,414E-03 0,01344173 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 7,414E-03 0,01343161 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 7,414E-03 0,01342151 ! defense response to virus GO:0051607 37 16 0,000 7,414E-03 0,01341142 ! positive regulation of cell killing GO:0031343 32 17 0,000 7,875E-03 0,01423585 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 7,875E-03 0,01422516 ! metencephalon development GO:0022037 30 17 0,000 7,875E-03 0,01421449 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 7,875E-03 0,01420384 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 7,875E-03 0,0141932 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 7,875E-03 0,01418257 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 7,875E-03 0,01417197 ! signal complex assembly GO:0007172 41 17 0,000 7,875E-03 0,01416137 ! endothelial cell migration GO:0043542 28 17 0,000 7,875E-03 0,0141508 ! inositol metabolic process GO:0006020 28 17 0,000 7,875E-03 0,01414024 ! gene silencing by RNA GO:0031047 36 17 0,000 7,875E-03 0,01412969 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 7,875E-03 0,01411916 ! glial cell development GO:0021782 27 17 0,000 7,875E-03 0,01410865 ! limbic system development GO:0021761 36 17 0,000 7,875E-03 0,01409815 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 7,875E-03 0,01408767 ! adult walking behavior GO:0007628 33 17 0,000 7,875E-03 0,01407721 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 7,875E-03 0,01406675 ! heart looping GO:0001947 30 17 0,000 7,875E-03 0,01405632 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 7,875E-03 0,0140459 ! regulation of viral genome replication GO:0045069 28 17 0,000 7,875E-03 0,0140355 ! myoblast differentiation GO:0045445 45 17 0,000 7,875E-03 0,01402511 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 7,875E-03 0,01401473 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 7,875E-03 0,01400437 ! regulation of survival gene product expression GO:0045884 33 17 0,000 7,875E-03 0,01399403 ! cardiac muscle tissue development GO:0048738 31 17 0,000 7,875E-03 0,0139837 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 7,875E-03 0,01397339 ! glycine metabolic process GO:0006544 28 17 0,000 7,875E-03 0,01396309 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 7,875E-03 0,01395281 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 7,875E-03 0,01394255 ! NAD metabolic process GO:0019674 29 17 0,000 7,875E-03 0,01393229 ! membrane budding GO:0006900 37 17 0,000 7,875E-03 0,01392206 ! DNA integration GO:0015074 29 17 0,000 7,875E-03 0,01391183 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 7,875E-03 0,01390163 ! regulation of protein binding GO:0043393 33 17 0,000 7,875E-03 0,01389144 ! nucleobase metabolic process GO:0009112 37 17 0,000 7,875E-03 0,01388126 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 7,875E-03 0,0138711 ! DNA unwinding during replication GO:0006268 27 17 0,000 7,875E-03 0,01386095 ! genitalia development GO:0048806 30 17 0,000 7,875E-03 0,01385082 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 7,875E-03 0,0138407 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 7,875E-03 0,0138306 ! neutrophil chemotaxis GO:0030593 27 17 0,000 7,875E-03 0,01382051 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 7,875E-03 0,01381044 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 7,875E-03 0,01380038 ! steroid catabolic process GO:0006706 31 17 0,000 7,875E-03 0,01379033 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 7,875E-03 0,0137803 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 7,875E-03 0,01377029 ! gas transport GO:0015669 25 17 0,000 7,875E-03 0,01376029 ! organic cation transport GO:0015695 31 17 0,000 7,875E-03 0,0137503 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 7,875E-03 0,01374033 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 7,875E-03 0,01373038 ! RNA 3'-end processing GO:0031123 34 17 0,000 7,875E-03 0,01372043 ! microspike assembly GO:0030035 36 17 0,000 7,875E-03 0,01371051 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 7,875E-03 0,01370059 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 7,875E-03 0,01369069 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 8,337E-03 0,01448244 ! neuron maturation GO:0042551 42 18 0,000 8,337E-03 0,01447199 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 8,337E-03 0,01446155 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 8,337E-03 0,01445114 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 8,337E-03 0,01444073 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 8,337E-03 0,01443034 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 8,337E-03 0,01441997 ! aminoglycan catabolic process GO:0006026 22 18 0,000 8,337E-03 0,01440961 ! memory GO:0007613 31 18 0,000 8,337E-03 0,01439926 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 8,337E-03 0,01438894 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 8,337E-03 0,01437862 ! patterning of blood vessels GO:0001569 39 18 0,000 8,337E-03 0,01436832 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 8,337E-03 0,01435804 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 8,337E-03 0,01434777 ! positive regulation of proteolysis GO:0045862 31 18 0,000 8,337E-03 0,01433751 ! epidermis morphogenesis GO:0048730 40 18 0,000 8,337E-03 0,01432727 ! glutamine metabolic process GO:0006541 29 18 0,000 8,337E-03 0,01431704 ! response to retinoic acid GO:0032526 26 18 0,000 8,337E-03 0,01430683 ! cell-substrate junction assembly GO:0007044 54 18 0,000 8,337E-03 0,01429663 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 8,337E-03 0,01428645 ! response to fungus GO:0009620 21 18 0,000 8,337E-03 0,01427628 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 8,337E-03 0,01426613 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 8,337E-03 0,01425599 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 8,337E-03 0,01424586 ! long-chain fatty acid transport GO:0015909 31 18 0,000 8,337E-03 0,01423575 ! peptide biosynthetic process GO:0043043 24 18 0,000 8,337E-03 0,01422566 ! vitamin transport GO:0051180 27 18 0,000 8,337E-03 0,01421557 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 8,337E-03 0,01420551 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 8,337E-03 0,01419545 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 8,337E-03 0,01418541 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 8,337E-03 0,01417539 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 8,337E-03 0,01416538 ! aromatic compound catabolic process GO:0019439 27 18 0,000 8,337E-03 0,01415538 ! nerve development GO:0021675 28 18 0,000 8,337E-03 0,0141454 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 8,337E-03 0,01413543 ! protein secretion GO:0009306 39 19 0,000 8,798E-03 0,01490701 ! positive regulation of translation GO:0045727 30 19 0,000 8,798E-03 0,01489652 ! negative regulation of defense response GO:0031348 25 19 0,000 8,798E-03 0,01488604 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 8,798E-03 0,01487558 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 8,798E-03 0,01486514 ! skin development GO:0043588 36 19 0,000 8,798E-03 0,0148547 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 8,798E-03 0,01484429 ! lipid phosphorylation GO:0046834 35 19 0,000 8,798E-03 0,01483388 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 8,798E-03 0,0148235 ! forelimb morphogenesis GO:0035136 32 19 0,000 8,798E-03 0,01481312 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 8,798E-03 0,01480276 ! bile acid metabolic process GO:0008206 29 19 0,000 8,798E-03 0,01479242 ! mitotic chromosome condensation GO:0007076 34 19 0,000 8,798E-03 0,01478209 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 8,798E-03 0,01477177 ! cerebral cortex development GO:0021987 36 19 0,000 8,798E-03 0,01476147 ! pigmentation during development GO:0048066 41 19 0,000 8,798E-03 0,01475119 ! cellular response to unfolded protein GO:0034620 33 19 0,000 8,798E-03 0,01474091 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 8,798E-03 0,01473066 ! heme metabolic process GO:0042168 36 19 0,000 8,798E-03 0,01472041 ! actin filament bundle formation GO:0051017 42 19 0,000 8,798E-03 0,01471018 ! neuromuscular junction development GO:0007528 34 19 0,000 8,798E-03 0,01469997 ! response to lipopolysaccharide GO:0032496 30 19 0,000 8,798E-03 0,01468977 ! plasma membrane fusion GO:0045026 28 19 0,000 8,798E-03 0,01467958 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 8,798E-03 0,01466941 ! peptide cross-linking GO:0018149 37 19 0,000 8,798E-03 0,01465925 ! protein export from nucleus GO:0006611 36 19 0,000 8,798E-03 0,0146491 ! heart process GO:0003015 30 19 0,000 8,798E-03 0,01463897 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 8,798E-03 0,01462885 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 8,798E-03 0,01461875 ! visual learning GO:0008542 36 19 0,000 8,798E-03 0,01460866 ! cellular pigmentation GO:0033059 36 19 0,000 8,798E-03 0,01459859 ! G1 phase GO:0051318 40 19 0,000 8,798E-03 0,01458853 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 8,798E-03 0,01457848 ! cell-cell junction organization GO:0045216 35 19 0,000 8,798E-03 0,01456845 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 8,798E-03 0,01455843 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 8,798E-03 0,01454842 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 8,798E-03 0,01453843 ! proximal/distal pattern formation GO:0009954 32 19 0,000 8,798E-03 0,01452845 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 8,798E-03 0,01451849 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 8,798E-03 0,01450854 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 8,798E-03 0,0144986 ! cilium assembly GO:0042384 37 19 0,000 8,798E-03 0,01448867 ! peptide hormone secretion GO:0030072 31 19 0,000 8,798E-03 0,01447876 ! protein import into nucleus, docking GO:0000059 41 20 0,000 9,259E-03 0,0152271 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 9,259E-03 0,0152167 ! positive regulation of ossification GO:0045778 47 20 0,000 9,259E-03 0,01520631 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 9,259E-03 0,01519594 ! protein amino acid deacetylation GO:0006476 29 20 0,000 9,259E-03 0,01518558 ! protein amino acid acetylation GO:0006473 39 20 0,000 9,259E-03 0,01517524 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 9,259E-03 0,01516491 ! cAMP metabolic process GO:0046058 36 20 0,000 9,259E-03 0,01515459 ! response to vitamin GO:0033273 31 20 0,000 9,259E-03 0,01514429 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 9,259E-03 0,015134 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 9,259E-03 0,01512373 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 9,259E-03 0,01511347 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 9,259E-03 0,01510322 ! response to alkaloid GO:0043279 38 20 0,000 9,259E-03 0,01509299 ! retinoid metabolic process GO:0001523 32 20 0,000 9,259E-03 0,01508277 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 9,259E-03 0,01507256 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 9,259E-03 0,01506237 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 9,259E-03 0,0150522 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 9,259E-03 0,01504203 ! DNA duplex unwinding GO:0032508 31 20 0,000 9,259E-03 0,01503188 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 9,259E-03 0,01502175 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 9,259E-03 0,01501162 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 9,259E-03 0,01500152 ! D-ribose metabolic process GO:0006014 29 20 0,000 9,259E-03 0,01499142 ! body fluid secretion GO:0007589 31 20 0,000 9,259E-03 0,01498134 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 9,259E-03 0,01497127 ! peptide secretion GO:0002790 35 20 0,000 9,259E-03 0,01496122 ! stem cell differentiation GO:0048863 53 20 0,000 9,259E-03 0,01495118 ! behavioral interaction between organisms GO:0051705 38 20 0,000 9,259E-03 0,01494115 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 9,259E-03 0,01493113 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 9,259E-03 0,01492113 ! sensory perception of pain GO:0019233 30 20 0,000 9,259E-03 0,01491115 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 9,259E-03 0,01490117 ! diencephalon development GO:0021536 34 20 0,000 9,259E-03 0,01489121 ! protein localization in mitochondrion GO:0070585 32 20 0,000 9,259E-03 0,01488126 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 9,259E-03 0,01487133 ! detection of chemical stimulus GO:0009593 37 20 0,000 9,259E-03 0,01486141 ! peptidyl-serine modification GO:0018209 43 20 0,000 9,259E-03 0,0148515 ! positive regulation of neurological system process GO:0031646 32 20 0,000 9,259E-03 0,01484161 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 9,259E-03 0,01483172 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 9,259E-03 0,01482186 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 9,259E-03 0,014812 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 9,259E-03 0,01480216 ! regulation of glucose import GO:0046324 29 20 0,000 9,259E-03 0,01479233 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 9,259E-03 0,01478252 ! actin filament-based movement GO:0030048 43 20 0,000 9,259E-03 0,01477271 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 9,259E-03 0,01476292 ! negative regulation of T cell activation GO:0050868 40 20 0,000 9,259E-03 0,01475315 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 9,259E-03 0,01474338 ! negative regulation of translation GO:0017148 29 20 0,000 9,259E-03 0,01473363 ! negative regulation of coagulation GO:0050819 29 20 0,000 9,259E-03 0,01472389 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 9,259E-03 0,01471417 ! regulation of cell killing GO:0031341 42 21 0,000 9,72E-03 0,01543635 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 9,72E-03 0,01542617 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 9,72E-03 0,015416 ! hormone secretion GO:0046879 38 21 0,000 9,72E-03 0,01540584 ! glycerol metabolic process GO:0006071 34 21 0,000 9,72E-03 0,0153957 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 9,72E-03 0,01538557 ! hindlimb morphogenesis GO:0035137 43 21 0,000 9,72E-03 0,01537546 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 9,72E-03 0,01536535 ! axis specification GO:0009798 38 21 0,000 9,72E-03 0,01535527 ! ovarian follicle development GO:0001541 35 21 0,000 9,72E-03 0,01534519 ! inactivation of MAPK activity GO:0000188 39 21 0,000 9,72E-03 0,01533513 ! smooth muscle contraction GO:0006939 46 21 0,000 9,72E-03 0,01532508 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 9,72E-03 0,01531504 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 9,72E-03 0,01530502 ! cell aging GO:0007569 44 21 0,000 9,72E-03 0,01529501 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 9,72E-03 0,01528501 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 9,72E-03 0,01527503 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 9,72E-03 0,01526506 ! cytolysis GO:0019835 24 21 0,000 9,72E-03 0,0152551 ! vasodilation GO:0042311 39 21 0,000 9,72E-03 0,01524516 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 9,72E-03 0,01523522 ! regulation of vasoconstriction GO:0019229 39 21 0,000 9,72E-03 0,01522531 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 9,72E-03 0,0152154 ! oogenesis GO:0048477 36 21 0,000 9,72E-03 0,01520551 ! DNA modification GO:0006304 34 21 0,000 9,72E-03 0,01519563 ! positive regulation of locomotion GO:0040017 39 21 0,000 9,72E-03 0,01518576 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 9,72E-03 0,0151759 ! detection of biotic stimulus GO:0009595 29 21 0,000 9,72E-03 0,01516606 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 9,72E-03 0,01515623 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 9,72E-03 0,01514642 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 9,72E-03 0,01513661 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 9,72E-03 0,01512682 ! vitamin A metabolic process GO:0006776 33 21 0,000 9,72E-03 0,01511705 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 9,72E-03 0,01510728 ! response to cytokine stimulus GO:0034097 63 21 0,000 9,72E-03 0,01509753 ! terpenoid metabolic process GO:0006721 37 21 0,000 9,72E-03 0,01508779 ! collagen catabolic process GO:0030574 28 21 0,000 9,72E-03 0,01507806 ! sperm-egg recognition GO:0035036 21 21 0,000 9,72E-03 0,01506834 ! gut development GO:0048565 39 21 0,000 9,72E-03 0,01505864 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,01018055 0,01576217 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,01018055 0,01575203 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,01018055 0,01574191 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,01018055 0,0157318 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,01018055 0,0157217 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,01018055 0,01571162 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,01018055 0,01570154 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,01018055 0,01569149 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,01018055 0,01568144 ! regeneration GO:0031099 41 22 0,000 0,01018055 0,01567141 ! keratinization GO:0031424 28 22 0,000 0,01018055 0,01566139 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,01018055 0,01565138 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,01018055 0,01564139 ! sensory perception of taste GO:0050909 28 22 0,000 0,01018055 0,0156314 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,01018055 0,01562143 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,01018055 0,01561148 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,01018055 0,01560153 ! vacuolar transport GO:0007034 36 22 0,000 0,01018055 0,0155916 ! lysosome organization GO:0007040 41 22 0,000 0,01018055 0,01558169 ! central nervous system neuron development GO:0021954 46 22 0,000 0,01018055 0,01557178 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,01018055 0,01556189 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,01018055 0,01555201 ! fucose metabolic process GO:0006004 39 22 0,000 0,01018055 0,01554214 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,01018055 0,01553228 ! ureteric bud development GO:0001657 43 22 0,000 0,01018055 0,01552244 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,01018055 0,01551261 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,01018055 0,01550279 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,01018055 0,01549299 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,01018055 0,01548319 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,01018055 0,01547341 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,01018055 0,01546364 ! sarcomere organization GO:0045214 30 22 0,000 0,01018055 0,01545389 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,01018055 0,01544414 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,01018055 0,01543441 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,01018055 0,01542469 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,01018055 0,01541498 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,01018055 0,01540529 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,01018055 0,01539561 ! protein stabilization GO:0050821 39 22 0,000 0,01018055 0,01538594 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,01064101 0,01607173 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,01064101 0,01606165 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,01064101 0,01605158 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,01064101 0,01604152 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,01064101 0,01603148 ! gluconeogenesis GO:0006094 33 23 0,000 0,01064101 0,01602145 ! viral genome replication GO:0019079 41 23 0,000 0,01064101 0,01601143 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,01064101 0,01600142 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,01064101 0,01599142 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,01064101 0,01598144 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,01064101 0,01597147 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,01064101 0,01596152 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,01064101 0,01595157 ! visual behavior GO:0007632 42 23 0,000 0,01064101 0,01594164 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,01064101 0,01593172 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,01064101 0,01592181 ! response to ethanol GO:0045471 46 23 0,000 0,01064101 0,01591191 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,01064101 0,01590203 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,01064101 0,01589216 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,01064101 0,0158823 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,01064101 0,01587246 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,01064101 0,01586262 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,01064101 0,0158528 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,01064101 0,01584299 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,01064101 0,01583319 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,01064101 0,01582341 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,01064101 0,01581363 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,01064101 0,01580387 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,01064101 0,01579412 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,01064101 0,01578438 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,01064101 0,01577466 ! fatty acid transport GO:0015908 44 23 0,000 0,01064101 0,01576494 ! platelet activation GO:0030168 37 23 0,000 0,01064101 0,01575524 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,01064101 0,01574555 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,01064101 0,01573588 ! hormone transport GO:0009914 40 23 0,000 0,01064101 0,01572621 ! cell-cell recognition GO:0009988 25 23 0,000 0,01064101 0,01571656 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,01064101 0,01570691 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,01064101 0,01569728 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,01064101 0,01568767 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,01064101 0,01567806 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,01064101 0,01566846 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,01110127 0,01633618 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,01110127 0,01632619 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,01110127 0,01631622 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,01110127 0,01630626 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,01110127 0,01629631 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,01110127 0,01628637 ! vesicle docking GO:0048278 47 24 0,000 0,01110127 0,01627645 ! spinal cord development GO:0021510 47 24 0,000 0,01110127 0,01626654 ! vacuole organization GO:0007033 43 24 0,000 0,01110127 0,01625664 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,01110127 0,01624675 ! digestive system process GO:0022600 39 24 0,000 0,01110127 0,01623687 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,01110127 0,01622701 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,01110127 0,01621715 ! regulation of behavior GO:0050795 43 24 0,000 0,01110127 0,01620731 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,01110127 0,01619749 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,01110127 0,01618767 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,01110127 0,01617786 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,01110127 0,01616807 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,01110127 0,01615829 ! membrane depolarization GO:0051899 39 24 0,000 0,01110127 0,01614852 ! pallium development GO:0021543 49 24 0,000 0,01110127 0,01613876 ! pentose metabolic process GO:0019321 35 24 0,000 0,01110127 0,01612902 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,01110127 0,01611928 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,01110127 0,01610956 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,01110127 0,01609985 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,01110127 0,01609015 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,01110127 0,01608047 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,01110127 0,01607079 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,01110127 0,01606113 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,01110127 0,01605147 ! regulation of amine transport GO:0051952 40 24 0,000 0,01110127 0,01604183 ! protein tetramerization GO:0051262 52 24 0,000 0,01110127 0,0160322 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,01156133 0,0166866 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,01156133 0,01667659 ! myelination GO:0042552 45 25 0,000 0,01156133 0,0166666 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,01156133 0,01665662 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,01156133 0,01664665 ! phototransduction GO:0007602 33 25 0,000 0,01156133 0,0166367 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,01156133 0,01662675 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,01156133 0,01661682 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,01156133 0,0166069 ! sperm motility GO:0030317 31 25 0,000 0,01156133 0,01659699 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,01156133 0,01658709 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,01156133 0,01657721 ! receptor metabolic process GO:0043112 46 25 0,000 0,01156133 0,01656734 ! chromosome condensation GO:0030261 45 25 0,000 0,01156133 0,01655747 ! response to starvation GO:0042594 42 25 0,000 0,01156133 0,01654762 ! osteoblast differentiation GO:0001649 60 25 0,000 0,01156133 0,01653779 ! response to endoplasmic reticulum stress GO:0034976 43 25 0,000 0,01156133 0,01652796 ! neural crest cell development GO:0014032 54 25 0,000 0,01156133 0,01651815 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,01156133 0,01650834 ! negative regulation of cell development GO:0010721 73 25 0,000 0,01156133 0,01649855 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,01156133 0,01648877 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,01156133 0,016479 ! interaction with host GO:0051701 62 25 0,000 0,01156133 0,01646925 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,01156133 0,0164595 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,01156133 0,01644977 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,01156133 0,01644005 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,01156133 0,01643033 ! immunoglobulin production GO:0002377 55 25 0,000 0,01156133 0,01642064 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,01156133 0,01641095 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,01156133 0,01640127 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,01156133 0,01639161 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,01156133 0,01638195 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,01156133 0,01637231 ! telomere organization GO:0032200 43 25 0,000 0,01156133 0,01636268 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,01156133 0,01635306 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,01156133 0,01634345 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,01202119 0,01698355 ! embryonic pattern specification GO:0009880 44 26 0,000 0,01202119 0,01697358 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,01202119 0,01696363 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,01202119 0,01695368 ! initiation of viral infection GO:0019059 57 26 0,000 0,01202119 0,01694375 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,01202119 0,01693383 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,01202119 0,01692392 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,01202119 0,01691403 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,01202119 0,01690414 ! molting cycle process GO:0022404 50 26 0,000 0,01202119 0,01689427 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,01202119 0,0168844 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,01202119 0,01687455 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,01202119 0,01686471 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,01202119 0,01685489 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,01202119 0,01684507 GO:0051297|centrosome organization, ! insulin receptor signaling pathway GO:0008286 64 26 0,000 0,01202119 0,01683526 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,01202119 0,01682547 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,01202119 0,01681569 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,01202119 0,01680592 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,01202119 0,01679616 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,01202119 0,01678641 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,01202119 0,01677667 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,01202119 0,01676695 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,01202119 0,01675723 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,01202119 0,01674753 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,01202119 0,01673784 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,01202119 0,01672816 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,01202119 0,01671849 ! blastocyst development GO:0001824 49 26 0,000 0,01202119 0,01670883 ! leukocyte proliferation GO:0070661 52 26 0,000 0,01202119 0,01669918 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,01202119 0,01668955 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,01202119 0,01667992 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,01248085 0,01730774 ! neuron fate commitment GO:0048663 48 27 0,000 0,01248085 0,01729777 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,01248085 0,01728781 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,01248085 0,01727787 ! iron ion transport GO:0006826 59 27 0,000 0,01248085 0,01726793 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,01248085 0,01725801 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,01248085 0,01724809 ! protein amino acid acylation GO:0043543 55 27 0,000 0,01248085 0,01723819 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,01248085 0,0172283 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,01248085 0,01721842 ! fat cell differentiation GO:0045444 50 27 0,000 0,01248085 0,01720856 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,01248085 0,0171987 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,01248085 0,01718886 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,01248085 0,01717902 ! autophagy GO:0006914 41 27 0,000 0,01248085 0,0171692 ! male gonad development GO:0008584 44 27 0,000 0,01248085 0,01715939 ! response to toxin GO:0009636 47 27 0,000 0,01248085 0,01714959 ! primary neural tube formation GO:0014020 51 27 0,000 0,01248085 0,0171398 ! base-excision repair GO:0006284 41 27 0,000 0,01248085 0,01713002 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,01248085 0,01712026 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,01248085 0,0171105 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,01248085 0,01710076 ! glutathione metabolic process GO:0006749 39 27 0,000 0,01248085 0,01709102 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,01248085 0,0170813 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,01248085 0,01707159 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,01248085 0,01706189 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,01248085 0,0170522 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,01294032 0,01766992 ! circadian rhythm GO:0007623 50 28 0,000 0,01294032 0,0176599 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,01294032 0,01764989 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,01294032 0,01763989 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,01294032 0,0176299 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,01294032 0,01761992 ! ER-nuclear signaling pathway GO:0006984 48 28 0,000 0,01294032 0,01760996 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,01294032 0,0176 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,01294032 0,01759006 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,01294032 0,01758012 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,01294032 0,0175702 ! synaptogenesis GO:0007416 42 28 0,000 0,01294032 0,01756029 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,01294032 0,0175504 ! lipid oxidation GO:0034440 43 28 0,000 0,01294032 0,01754051 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,01294032 0,01753063 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,01294032 0,01752077 ! translational initiation GO:0006413 65 29 0,000 0,01339958 0,01813239 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,01339958 0,0181222 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,01339958 0,01811202 ! regulation of pH GO:0006885 43 29 0,000 0,01339958 0,01810185 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,01339958 0,01809169 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,01339958 0,01808154 ! catechol metabolic process GO:0009712 54 29 0,000 0,01339958 0,01807141 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,01339958 0,01806128 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,01339958 0,01805117 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,01339958 0,01804107 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,01339958 0,01803098 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,01339958 0,0180209 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,01339958 0,01801083 ! cell fate determination GO:0001709 60 29 0,000 0,01339958 0,01800078 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,01339958 0,01799073 ! detection of light stimulus GO:0009583 38 29 0,000 0,01339958 0,0179807 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 0,01339958 0,01797068 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,01339958 0,01796066 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,01339958 0,01795066 ! tissue homeostasis GO:0001894 48 29 0,000 0,01339958 0,01794068 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,01339958 0,0179307 ! phenol metabolic process GO:0018958 55 30 0,000 0,01385865 0,01853469 ! zinc ion transport GO:0006829 45 30 0,000 0,01385865 0,01852439 ! membrane docking GO:0022406 61 30 0,000 0,01385865 0,01851411 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,01385865 0,01850383 ! cell junction assembly GO:0034329 78 30 0,000 0,01385865 0,01849357 ! regulation of innate immune response GO:0045088 51 30 0,000 0,01385865 0,01848332 ! acute-phase response GO:0006953 49 30 0,000 0,01385865 0,01847308 ! myofibril assembly GO:0030239 47 30 0,000 0,01385865 0,01846285 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,01385865 0,01845263 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,01385865 0,01844243 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,01385865 0,01843223 ! phospholipid transport GO:0015914 51 30 0,000 0,01385865 0,01842205 ! ensheathment of neurons GO:0007272 57 30 0,000 0,01385865 0,01841188 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,01385865 0,01840172 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,01385865 0,01839157 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,01385865 0,01838143 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,01385865 0,0183713 ! eye morphogenesis GO:0048592 60 30 0,000 0,01385865 0,01836118 ! regulation of B cell activation GO:0050864 50 30 0,000 0,01385865 0,01835108 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,01431752 0,01894827 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,01431752 0,01893785 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,01431752 0,01892744 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,01431752 0,01891705 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,01431752 0,01890667 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,01431752 0,0188963 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,01431752 0,01888594 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,01431752 0,01887559 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,01431752 0,01886525 ! ovulation cycle process GO:0022602 49 31 0,000 0,01431752 0,01885492 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,01431752 0,01884461 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,01431752 0,01883431 ! peptide transport GO:0015833 55 31 0,000 0,01431752 0,01882401 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,01431752 0,01881373 ! iron ion homeostasis GO:0055072 54 31 0,000 0,01431752 0,01880346 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,01431752 0,01879321 ! mesoderm formation GO:0001707 69 31 0,000 0,01431752 0,01878296 ! natural killer cell activation GO:0030101 45 31 0,000 0,01431752 0,01877272 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,01431752 0,0187625 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,01431752 0,01875228 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,01431752 0,01874208 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,01431752 0,01873189 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,01431752 0,01872171 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,01477619 0,01931098 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,01477619 0,01930049 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,01477619 0,01929002 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,01477619 0,01927956 ! cholesterol transport GO:0030301 56 32 0,000 0,01477619 0,01926911 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,01477619 0,01925867 ! spliceosome assembly GO:0000245 67 32 0,000 0,01477619 0,01924824 ! spindle organization GO:0007051 46 32 0,000 0,01477619 0,01923783 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,01477619 0,01922742 ! metanephros development GO:0001656 74 32 0,000 0,01477619 0,01921703 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,01477619 0,01920665 ! response to ionizing radiation GO:0010212 65 32 0,000 0,01477619 0,01919628 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,01477619 0,01918592 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,01477619 0,01917557 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,01477619 0,01916523 ! muscle cell development GO:0055001 49 32 0,000 0,01477619 0,01915491 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,01477619 0,01914459 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,01477619 0,01913429 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,01477619 0,019124 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,01477619 0,01911371 ! ovulation cycle GO:0042698 51 32 0,000 0,01477619 0,01910344 ! peripheral nervous system development GO:0007422 64 32 0,000 0,01477619 0,01909318 ! BMP signaling pathway GO:0030509 64 32 0,000 0,01477619 0,01908293 ! hindbrain development GO:0030902 61 32 0,000 0,01477619 0,0190727 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,01477619 0,01906247 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,01477619 0,01905225 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,01477619 0,01904205 ! gene silencing GO:0016458 65 32 0,000 0,01477619 0,01903186 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,01523466 0,01961187 ! post-embryonic development GO:0009791 69 33 0,000 0,01523466 0,01960139 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,01523466 0,01959091 ! protein targeting to membrane GO:0006612 68 33 0,000 0,01523466 0,01958044 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,01523466 0,01956999 ! ceramide metabolic process GO:0006672 64 33 0,000 0,01523466 0,01955955 ! formation of primary germ layer GO:0001704 72 33 0,000 0,01523466 0,01954912 ! cell fate specification GO:0001708 52 33 0,000 0,01523466 0,01953869 ! sterol transport GO:0015918 57 33 0,000 0,01523466 0,01952828 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,01523466 0,01951789 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,01523466 0,0195075 ! adult locomotory behavior GO:0008344 59 33 0,000 0,01523466 0,01949712 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,01523466 0,01948676 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,01523466 0,0194764 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,01569293 0,02005162 ! glial cell differentiation GO:0010001 63 34 0,000 0,01569293 0,02004098 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,01569293 0,02003034 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,01569293 0,02001972 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,01569293 0,02000911 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,01569293 0,01999852 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,01569293 0,01998793 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,01569293 0,01997735 ! mismatch repair GO:0006298 46 34 0,000 0,01569293 0,01996679 ! spermatid development GO:0007286 63 34 0,000 0,01569293 0,01995624 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,01569293 0,01994569 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,01569293 0,01993516 ! placenta development GO:0001890 53 34 0,000 0,01569293 0,01992464 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,01569293 0,01991413 ! regulation of muscle development GO:0048634 70 35 0,000 0,01615101 0,02048462 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,01615101 0,02047383 ! negative regulation of secretion GO:0051048 63 35 0,000 0,01615101 0,02046305 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,01615101 0,02045228 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,01615101 0,02044152 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,01615101 0,02043077 ! odontogenesis GO:0042476 66 35 0,000 0,01615101 0,02042004 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,01615101 0,02040931 ! female gonad development GO:0008585 58 35 0,000 0,01615101 0,0203986 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,01615101 0,0203879 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,01615101 0,0203772 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,01615101 0,02036652 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,01615101 0,02035586 ! cytokine production GO:0001816 59 35 0,000 0,01615101 0,0203452 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,01615101 0,02033455 ! neural tube formation GO:0001841 67 35 0,000 0,01615101 0,02032392 ! vesicle localization GO:0051648 64 35 0,000 0,01615101 0,02031329 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,01660889 0,02087826 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,01660889 0,02086735 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,01660889 0,02085646 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,01660889 0,02084558 ! cell junction organization GO:0034330 86 36 0,000 0,01660889 0,02083471 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,01660889 0,02082386 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,01660889 0,02081301 ! positive regulation of cell development GO:0010720 80 36 0,000 0,01660889 0,02080218 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,01660889 0,02079135 ! regulation of proteolysis GO:0030162 72 36 0,000 0,01660889 0,02078054 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,01660889 0,02076974 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,01660889 0,02075895 ! aerobic respiration GO:0009060 55 36 0,000 0,01660889 0,02074817 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,01660889 0,02073741 ! embryonic organ development GO:0048568 57 36 0,000 0,01660889 0,02072665 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,01660889 0,02071591 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,01660889 0,02070517 ! RNA export from nucleus GO:0006405 56 37 0,000 0,01706657 0,02126471 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,01706657 0,02125371 ! meiosis I GO:0007127 65 37 0,000 0,01706657 0,02124271 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,01706657 0,02123173 ! sister chromatid segregation GO:0000819 58 37 0,000 0,01706657 0,02122076 ! actomyosin structure organization GO:0031032 62 37 0,000 0,01706657 0,02120979 ! organic anion transport GO:0015711 68 37 0,000 0,01706657 0,02119884 ! tissue remodeling GO:0048771 76 37 0,000 0,01706657 0,02118791 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,01706657 0,02117698 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,01706657 0,02116606 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,01706657 0,02115516 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,01706657 0,02114426 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,01706657 0,02113338 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,01706657 0,02112251 ! glycogen metabolic process GO:0005977 61 37 0,000 0,01706657 0,02111165 ! pigment metabolic process GO:0042440 80 37 0,000 0,01706657 0,0211008 ! spermatid differentiation GO:0048515 66 37 0,000 0,01706657 0,02108996 ! cellular response to insulin stimulus GO:0032869 82 37 0,000 0,01706657 0,02107914 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,01752405 0,02163308 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,01752405 0,02162198 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,01752405 0,0216109 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,01752405 0,02159983 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,01752405 0,02158877 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,01752405 0,02157772 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,01752405 0,02156668 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,01752405 0,02155566 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 67 38 0,000 0,01752405 0,02154464 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,01752405 0,02153364 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,01752405 0,02152265 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,01752405 0,02151167 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,01752405 0,0215007 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,01752405 0,02148974 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,01752405 0,02147879 ! glucan metabolic process GO:0044042 62 38 0,000 0,01752405 0,02146785 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,01798133 0,02201684 ! mammary gland development GO:0030879 86 39 0,000 0,01798133 0,02200564 ! learning GO:0007612 77 39 0,000 0,01798133 0,02199445 ! ear morphogenesis GO:0042471 60 39 0,000 0,01798133 0,02198328 ! organic ether metabolic process GO:0018904 55 39 0,000 0,01798133 0,02197211 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,01798133 0,02196096 ! segmentation GO:0035282 67 39 0,000 0,01798133 0,02194982 ! ion transmembrane transport GO:0034220 66 39 0,000 0,01798133 0,02193869 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,01798133 0,02192757 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,01798133 0,02191646 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,01798133 0,02190536 ! RNA modification GO:0009451 57 39 0,000 0,01798133 0,02189428 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,01798133 0,0218832 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,01843842 0,02242813 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,01843842 0,0224168 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,01843842 0,02240548 ! feeding behavior GO:0007631 59 40 0,000 0,01843842 0,02239417 ! negative regulation of binding GO:0051100 72 40 0,000 0,01843842 0,02238287 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,01843842 0,02237158 ! mesenchymal cell development GO:0014031 87 40 0,000 0,01843842 0,0223603 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,01843842 0,02234904 ! maintenance of protein location GO:0045185 91 40 0,000 0,01843842 0,02233779 ! cytokinesis GO:0000910 72 40 0,000 0,01843842 0,02232654 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,01889531 0,02286827 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,01889531 0,02285677 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,01889531 0,02284529 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,01889531 0,02283381 ! gliogenesis GO:0042063 88 41 0,000 0,01889531 0,02282235 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,01889531 0,0228109 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,01889531 0,02279946 ! T cell differentiation GO:0030217 81 41 0,000 0,01889531 0,02278803 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,01889531 0,02277661 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,01889531 0,02276521 ! female gamete generation GO:0007292 61 41 0,000 0,01889531 0,02275381 ! polyol metabolic process GO:0019751 66 41 0,000 0,01889531 0,02274243 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,01889531 0,02273106 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,019352 0,02326882 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,019352 0,0232572 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,019352 0,02324559 ! regulation of tube size GO:0035150 71 42 0,000 0,019352 0,02323399 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,019352 0,0232224 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,019352 0,02321083 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,019352 0,02319926 ! regulation of intracellular protein transport GO:0033157 80 42 0,000 0,019352 0,02318771 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,019352 0,02317617 ! neuron migration GO:0001764 79 42 0,000 0,019352 0,02316464 ! regulation of protein secretion GO:0050708 71 42 0,000 0,019352 0,02315312 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,019352 0,02314161 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,0198085 0,02367573 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,0198085 0,02366397 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,0198085 0,02365223 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,0198085 0,0236405 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,0198085 0,02362878 ! glucose transport GO:0015758 65 43 0,000 0,0198085 0,02361707 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,0198085 0,02360537 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,0198085 0,02359369 ! neural tube development GO:0021915 77 43 0,000 0,0198085 0,02358201 ! regulation of epithelial cell proliferation GO:0050678 111 43 0,000 0,0198085 0,02357035 ! striated muscle contraction GO:0006941 77 43 0,000 0,0198085 0,0235587 ! phagocytosis GO:0006909 90 43 0,000 0,0198085 0,02354706 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,0198085 0,02353543 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,02026479 0,02406569 ! hexose transport GO:0008645 67 44 0,000 0,02026479 0,02405382 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,02026479 0,02404196 ! male sex differentiation GO:0046661 76 44 0,000 0,02026479 0,02403011 ! double-strand break repair GO:0006302 81 44 0,000 0,02026479 0,02401827 ! biopolymer methylation GO:0043414 84 44 0,000 0,02026479 0,02400645 ! B cell differentiation GO:0030183 107 44 0,000 0,02026479 0,02399463 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,02026479 0,02398283 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,02026479 0,02397104 ! developmental growth GO:0048589 82 44 0,000 0,02026479 0,02395926 ! maintenance of location in cell GO:0051651 97 44 0,000 0,02026479 0,02394749 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,02072089 0,02447446 ! glycolysis GO:0006096 65 45 0,000 0,02072089 0,02446245 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,02072089 0,02445045 ! leukocyte migration GO:0050900 68 45 0,000 0,02072089 0,02443847 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,02072089 0,02442649 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,02072089 0,02441453 ! induction of apoptosis by intracellular signals GO:0008629 93 45 0,000 0,02072089 0,02440258 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,02072089 0,02439064 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,02072089 0,02437871 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,02072089 0,0243668 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,02072089 0,0243549 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,02072089 0,024343 ! cell growth GO:0016049 84 45 0,000 0,02072089 0,02433112 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 0,000 0,0211768 0,02485433 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,0211768 0,02484221 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 0,000 0,0211768 0,0248301 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,0211768 0,02481801 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,0211768 0,02480593 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,0211768 0,02479386 ! pigmentation GO:0043473 100 46 0,000 0,0211768 0,0247818 ! response to insulin stimulus GO:0032868 95 46 0,000 0,0211768 0,02476975 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,0211768 0,02475771 ! positive regulation of defense response GO:0031349 76 47 0,000 0,0216325 0,02527819 ! response to calcium ion GO:0051592 81 47 0,000 0,0216325 0,02526592 ! endosome transport GO:0016197 108 47 0,000 0,0216325 0,02525366 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,0216325 0,02524142 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,0216325 0,02522918 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,0216325 0,02521696 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,0216325 0,02520475 ! JNK cascade GO:0007254 91 47 0,000 0,0216325 0,02519255 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,0216325 0,02518036 ! methylation GO:0032259 90 47 0,000 0,0216325 0,02516818 ! protein homooligomerization GO:0051260 76 47 0,000 0,0216325 0,02515602 ! positive regulation of cell cycle GO:0045787 89 48 0,000 0,02208801 0,02567331 ! mitochondrial transport GO:0006839 82 48 0,000 0,02208801 0,02566092 ! Notch signaling pathway GO:0007219 96 48 0,000 0,02208801 0,02564853 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,02208801 0,02563616 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,02208801 0,0256238 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,02208801 0,02561145 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,02208801 0,02559911 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,02208801 0,02558679 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,02208801 0,02557447 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,02208801 0,02556217 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,02254332 0,02607656 ! regulation of action potential GO:0001508 95 49 0,000 0,02254332 0,02606402 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,02254332 0,02605151 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,02254332 0,026039 ! regulation of ion transport GO:0043269 77 49 0,000 0,02254332 0,0260265 ! peptide metabolic process GO:0006518 76 49 0,000 0,02254332 0,02601402 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,02254332 0,02600155 ! endocrine system development GO:0035270 104 49 0,000 0,02254332 0,02598909 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,02254332 0,02597665 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,02254332 0,02596421 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,02254332 0,02595179 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,02254332 0,02593938 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,02299844 0,0264504 ! neuromuscular process GO:0050905 99 50 0,000 0,02299844 0,02643776 ! regulation of ossification GO:0030278 117 50 0,000 0,02299844 0,02642514 ! inner ear development GO:0048839 79 50 0,000 0,02299844 0,02641253 ! histone modification GO:0016570 91 50 0,000 0,02299844 0,02639992 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,02299844 0,02638734 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,02299844 0,02637476 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,02299844 0,02636219 ! positive regulation of binding GO:0051099 78 51 0,000 0,02345336 0,02687085 ! viral infectious cycle GO:0019058 99 51 0,000 0,02345336 0,02685806 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,02345336 0,02684528 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,02345336 0,02683251 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,02345336 0,02681976 ! excretion GO:0007588 83 51 0,000 0,02345336 0,02680702 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,02345336 0,02679429 ! chromatin remodeling GO:0006338 109 51 0,000 0,02345336 0,02678157 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,02345336 0,02676887 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,02345336 0,02675618 ! vesicle organization GO:0016050 107 51 0,000 0,02345336 0,0267435 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,02345336 0,02673083 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 0,000 0,02345336 0,02671817 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,02345336 0,02670553 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,02390808 0,02721042 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,02390808 0,02719756 ! membrane fusion GO:0006944 110 52 0,000 0,02390808 0,0271847 ! positive regulation of growth GO:0045927 90 52 0,000 0,02390808 0,02717186 ! covalent chromatin modification GO:0016569 101 52 0,000 0,02390808 0,02715903 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,02390808 0,02714622 ! amino acid activation GO:0043038 92 52 0,000 0,02390808 0,02713341 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,02390808 0,02712062 ! synapse organization GO:0050808 85 52 0,000 0,02390808 0,02710784 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,0243626 0,02761018 ! RNA catabolic process GO:0006401 93 53 0,000 0,0243626 0,02759718 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,0243626 0,0275842 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,0243626 0,02757122 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,0243626 0,02755826 ! cell maturation GO:0048469 100 53 0,000 0,0243626 0,02754531 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,0243626 0,02753237 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,0243626 0,02751945 ! response to UV GO:0009411 104 53 0,000 0,0243626 0,02750653 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,02481693 0,02800635 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,02481693 0,02799322 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,02481693 0,0279801 ! cell recognition GO:0008037 85 54 0,000 0,02481693 0,027967 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,02481693 0,0279539 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,02481693 0,02794082 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,02481693 0,02792775 ! chloride transport GO:0006821 90 55 0,000 0,02527106 0,02842551 ! glucose catabolic process GO:0006007 82 55 0,000 0,02527106 0,02841223 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,02527106 0,02839896 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,02527106 0,0283857 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,02527106 0,02837246 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,02527106 0,02835922 ! aging GO:0007568 103 55 0,000 0,02527106 0,028346 ! gastrulation GO:0007369 112 55 0,000 0,02527106 0,02833279 ! heart morphogenesis GO:0003007 97 55 0,000 0,02527106 0,0283196 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,02527106 0,02830641 ! RNA elongation GO:0006354 79 55 0,000 0,02527106 0,02829324 ! nuclear export GO:0051168 97 55 0,000 0,02527106 0,02828008 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,02527106 0,02826693 ! regulation of actin filament length GO:0030832 105 56 0,000 0,025725 0,02876131 ! sensory perception of smell GO:0007608 80 56 0,000 0,025725 0,02874795 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,025725 0,02873461 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,025725 0,02872127 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,025725 0,02870795 ! regulation of DNA replication GO:0006275 101 56 0,000 0,025725 0,02869464 ! proton transport GO:0015992 94 56 0,000 0,025725 0,02868135 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,025725 0,02866806 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 0,000 0,02617874 0,0291602 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,02617874 0,02914671 ! muscle fiber development GO:0048747 112 57 0,000 0,02617874 0,02913323 ! positive regulation of cell migration GO:0030335 126 57 0,000 0,02617874 0,02911976 ! lipid modification GO:0030258 97 57 0,000 0,02617874 0,0291063 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,02617874 0,02909286 ! regulation of intracellular transport GO:0032386 101 57 0,000 0,02617874 0,02907943 ! maintenance of location GO:0051235 118 57 0,000 0,02617874 0,02906601 ! hydrogen transport GO:0006818 97 58 0,000 0,02663228 0,02955593 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,02663228 0,02954231 ! regulation of endocytosis GO:0030100 91 58 0,000 0,02663228 0,02952869 ! adult behavior GO:0030534 99 58 0,000 0,02663228 0,02951509 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,02663228 0,0295015 ! positive regulation of secretion GO:0051047 95 59 0,000 0,02708563 0,02998988 ! regulation of cellular component size GO:0032535 109 59 0,000 0,02708563 0,02997609 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,02708563 0,02996231 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,02708563 0,02994854 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,02708563 0,02993478 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,02708563 0,02992104 ! establishment of organelle localization GO:0051656 109 59 0,000 0,02708563 0,0299073 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,02753878 0,03039371 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,02753878 0,03037978 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,02753878 0,03036586 ! regulation of heart contraction GO:0008016 110 60 0,000 0,02753878 0,03035195 ! camera-type eye development GO:0043010 116 60 0,000 0,02753878 0,03033805 ! protein amino acid autophosphorylation GO:0046777 141 60 0,000 0,02753878 0,03032416 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,02753878 0,03031029 ! kidney development GO:0001822 122 60 0,000 0,02753878 0,03029643 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,02799173 0,03078067 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,02799173 0,03076661 ! mesoderm development GO:0007498 119 61 0,000 0,02799173 0,03075256 ! tRNA processing GO:0008033 89 61 0,000 0,02799173 0,03073852 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,02799173 0,0307245 ! response to peptide hormone stimulus GO:0043434 122 61 0,000 0,02799173 0,03071049 ! ear development GO:0043583 103 62 0,000 0,02844449 0,031193 ! viral reproductive process GO:0022415 126 62 0,000 0,02844449 0,03117879 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,02844449 0,03116459 ! gonad development GO:0008406 98 62 0,000 0,02844449 0,03115041 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,02844449 0,03113623 ! regulation of mitosis GO:0007088 105 63 0,000 0,02889705 0,03161724 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,02889705 0,03160287 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,02889705 0,03158851 ! detection of external stimulus GO:0009581 91 63 0,000 0,02889705 0,03157416 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,02889705 0,03155983 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,02889705 0,03154551 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,02934942 0,03202481 ! cell redox homeostasis GO:0045454 102 64 0,000 0,02934942 0,03201029 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,02934942 0,03199579 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,02934942 0,0319813 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,02934942 0,03196682 ! positive regulation of cell motion GO:0051272 146 64 0,000 0,02934942 0,03195236 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,02980159 0,03242995 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,02980159 0,03241529 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,02980159 0,03240065 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,02980159 0,03238601 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,02980159 0,03237139 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,03025357 0,03284751 ! actin filament organization GO:0007015 148 66 0,000 0,03025357 0,03283269 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,03025357 0,03281789 ! extracellular matrix organization GO:0030198 133 66 0,000 0,03025357 0,0328031 ! secondary metabolic process GO:0019748 116 66 0,000 0,03025357 0,03278833 ! developmental maturation GO:0021700 116 66 0,000 0,03025357 0,03277356 ! cell projection assembly GO:0030031 120 66 0,000 0,03025357 0,03275881 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,03070535 0,03323305 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,03070535 0,03321811 ! negative regulation of protein kinase activity GO:0006469 130 67 0,000 0,03070535 0,03320318 ! negative regulation of cell growth GO:0030308 132 67 0,000 0,03070535 0,03318826 ! activation of MAPK activity GO:0000187 115 67 0,000 0,03070535 0,03317336 ! lung development GO:0030324 144 67 0,000 0,03070535 0,03315847 ! chromosome segregation GO:0007059 113 67 0,000 0,03070535 0,03314359 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,03070535 0,03312873 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,03070535 0,03311388 ! hexose catabolic process GO:0019320 104 67 0,000 0,03070535 0,03309904 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,03070535 0,03308422 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,03070535 0,03306941 ! adaptive immune response GO:0002250 119 67 0,000 0,03070535 0,03305462 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,03070535 0,03303983 ! amino acid transport GO:0006865 125 68 0,000 0,03115693 0,03351076 ! negative regulation of kinase activity GO:0033673 131 68 0,000 0,03115693 0,03349579 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,03115693 0,03348083 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,03115693 0,03346588 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,03115693 0,03345095 ! viral reproduction GO:0016032 134 68 0,000 0,03115693 0,03343603 ! regulation of lipase activity GO:0060191 130 68 0,000 0,03115693 0,03342112 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,03115693 0,03340623 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,03115693 0,03339135 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,03160832 0,03386003 ! negative regulation of cell size GO:0045792 134 69 0,000 0,03160832 0,03384496 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,03160832 0,0338299 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,03160832 0,03381486 ! urogenital system development GO:0001655 137 69 0,000 0,03160832 0,03379983 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,03160832 0,03378482 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,03160832 0,03376981 ! antigen processing and presentation GO:0019882 104 69 0,000 0,03160832 0,03375483 ! appendage morphogenesis GO:0035107 135 70 0,000 0,03205952 0,03422147 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 0,000 0,03205952 0,0342063 ! amine catabolic process GO:0009310 117 71 0,000 0,03251052 0,03467212 ! reproductive structure development GO:0048608 113 71 0,000 0,03251052 0,03465676 ! appendage development GO:0048736 136 71 0,000 0,03251052 0,03464141 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,03251052 0,03462607 ! B cell activation GO:0042113 160 71 0,000 0,03251052 0,03461075 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,03251052 0,03459544 ! regulation of immune effector process GO:0002697 137 71 0,000 0,03251052 0,03458015 ! acute inflammatory response GO:0002526 113 72 0,000 0,03296132 0,03504416 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,03296132 0,03502868 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,03296132 0,03501322 ! carbohydrate transport GO:0008643 110 72 0,000 0,03296132 0,03499776 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,03296132 0,03498233 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,03296132 0,0349669 ! negative regulation of transferase activity GO:0051348 140 72 0,000 0,03296132 0,03495149 ! respiratory system development GO:0060541 153 72 0,000 0,03296132 0,03493609 ! learning or memory GO:0007611 147 73 0,000 0,03341193 0,03539811 ! regulation of blood pressure GO:0008217 125 73 0,000 0,03341193 0,03538253 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,03341193 0,03536696 ! axon guidance GO:0007411 139 73 0,000 0,03341193 0,03535141 ! fertilization GO:0009566 90 73 0,000 0,03341193 0,03533587 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,03386234 0,03579648 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,03386234 0,03578076 ! neurotransmitter transport GO:0006836 123 74 0,000 0,03386234 0,03576505 ! meiosis GO:0007126 121 74 0,000 0,03386234 0,03574936 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,03386234 0,03573368 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,03386234 0,03571802 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,03386234 0,03570236 ! eye development GO:0001654 143 74 0,000 0,03386234 0,03568673 ! organelle localization GO:0051640 136 74 0,000 0,03386234 0,0356711 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,03431256 0,03612955 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,03431256 0,03611374 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,03431256 0,03609795 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,03431256 0,03608218 ! meiotic cell cycle GO:0051321 122 75 0,000 0,03431256 0,03606641 ! rhythmic process GO:0048511 128 75 0,000 0,03431256 0,03605066 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,03431256 0,03603493 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,03476258 0,03649161 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,03476258 0,0364757 ! defense response to bacterium GO:0042742 89 76 0,000 0,03476258 0,0364598 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,03476258 0,03644391 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,03476258 0,03642804 ! regulation of catabolic process GO:0009894 161 76 0,000 0,03476258 0,03641218 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,03521241 0,03686731 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,03521241 0,03685127 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,03521241 0,03683525 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,03521241 0,03681924 ! blood coagulation GO:0007596 146 78 0,000 0,03566205 0,03727319 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,03566205 0,03725701 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,03566205 0,03724084 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,03566205 0,03722468 ! protein oligomerization GO:0051259 139 78 0,000 0,03566205 0,03720854 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,03611149 0,03766114 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,03611149 0,03764482 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,03611149 0,03762852 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,03611149 0,03761223 ! positive regulation of phosphorylation GO:0042327 129 79 0,000 0,03611149 0,03759595 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,03611149 0,03757969 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,03656073 0,03803075 ! response to metal ion GO:0010038 140 80 0,000 0,03656073 0,03801432 ! muscle cell differentiation GO:0042692 159 80 0,000 0,03656073 0,0379979 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,03656073 0,03798149 ! protein import into nucleus GO:0006606 158 80 0,000 0,03656073 0,0379651 ! inorganic anion transport GO:0015698 138 80 0,000 0,03656073 0,03794872 ! T cell activation GO:0042110 168 81 0,000 0,03700979 0,03839825 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 0,000 0,03700979 0,0383817 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 0,000 0,03700979 0,03836516 ! digestion GO:0007586 112 81 0,000 0,03700979 0,03834864 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,03700979 0,03833213 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,03700979 0,03831564 ! nuclear import GO:0051170 161 81 0,000 0,03700979 0,03829916 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,03700979 0,03828269 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,03745864 0,03873034 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,03745864 0,0387137 ! response to drug GO:0042493 143 82 0,000 0,03745864 0,03869708 ! response to nutrient GO:0007584 125 82 0,000 0,03745864 0,03868047 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,03745864 0,03866388 ! cellular response to hormone stimulus GO:0032870 167 82 0,000 0,03745864 0,0386473 ! response to oxygen levels GO:0070482 176 83 0,000 0,0379073 0,03909343 ! regulation of lyase activity GO:0051339 160 83 0,000 0,0379073 0,03907668 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,03835577 0,03952205 ! hemostasis GO:0007599 158 84 0,000 0,03835577 0,03950513 ! negative regulation of transport GO:0051051 153 84 0,000 0,03835577 0,03948823 ! negative regulation of growth GO:0045926 155 84 0,000 0,03835577 0,03947134 ! regulation of ligase activity GO:0051340 142 84 0,000 0,03835577 0,03945446 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,03835577 0,0394376 ! nucleosome assembly GO:0006334 122 85 0,000 0,03880405 0,03988148 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,03880405 0,03986445 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,03880405 0,03984743 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,03925213 0,04029037 ! response to inorganic substance GO:0010035 153 86 0,000 0,03925213 0,04027319 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,03925213 0,04025602 ! chromatin assembly GO:0031497 124 86 0,000 0,03925213 0,04023887 ! tube morphogenesis GO:0035239 176 86 0,000 0,03925213 0,04022173 ! mitochondrion organization GO:0007005 148 86 0,000 0,03925213 0,04020461 ! alcohol catabolic process GO:0046164 130 86 0,000 0,03925213 0,0401875 ! amine transport GO:0015837 155 86 0,000 0,03925213 0,0401704 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,03970001 0,04061149 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,03970001 0,04059423 ! protein localization in nucleus GO:0034504 176 87 0,000 0,03970001 0,04057699 ! regulation of protein transport GO:0051223 154 87 0,000 0,03970001 0,04055976 GO:0070201|regulation of establishment of protein localization, ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,04014771 0,04099974 ! regulation of DNA binding GO:0051101 155 88 0,000 0,04014771 0,04098234 ! gland development GO:0048732 206 88 0,000 0,04014771 0,04096496 ! regulation of neurological system process GO:0031644 148 88 0,000 0,04014771 0,0409476 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,04014771 0,04093025 ! cellular defense response GO:0006968 114 89 0,000 0,0405952 0,04136894 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,0405952 0,04135142 ! regulation of cell adhesion GO:0030155 212 89 0,000 0,0405952 0,04133392 ! ossification GO:0001503 188 90 0,000 0,04104251 0,04177169 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,04104251 0,04175403 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,04104251 0,04173638 ! sex differentiation GO:0007548 145 90 0,000 0,04104251 0,04171875 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,04104251 0,04170113 ! bone development GO:0060348 189 91 0,000 0,04148962 0,04213762 ! sterol metabolic process GO:0016125 152 91 0,000 0,04148962 0,04211984 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,04148962 0,04210208 ! regulation of defense response GO:0031347 149 92 0,000 0,04193654 0,04253765 ! nucleosome organization GO:0034728 138 92 0,000 0,04193654 0,04251973 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,04193654 0,04250182 ! vitamin metabolic process GO:0006766 139 92 0,000 0,04193654 0,04248392 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,04238326 0,0429184 GO:0010498|proteasomal protein catabolic process, ! positive regulation of MAP kinase activity GO:0043406 160 93 0,000 0,04238326 0,04290035 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,04238326 0,04288231 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,04238326 0,04286428 ! regulation of membrane potential GO:0042391 164 93 0,000 0,04238326 0,04284627 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,04238326 0,04282828 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,04282979 0,04326133 ! female pregnancy GO:0007565 164 94 0,000 0,04282979 0,04324317 ! transcription initiation GO:0006352 153 94 0,000 0,04282979 0,04322503 ! regulation of T cell activation GO:0050863 158 94 0,000 0,04282979 0,04320691 ! interphase of mitotic cell cycle GO:0051329 209 95 0,000 0,04327613 0,04363888 ! forebrain development GO:0030900 188 95 0,000 0,04327613 0,0436206 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,04327613 0,04360233 ! leukocyte differentiation GO:0002521 202 96 0,000 0,04372227 0,0440334 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,04372227 0,04401498 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,04372227 0,04399657 ! positive regulation of immune response GO:0050778 156 96 0,000 0,04372227 0,04397817 ! detection of stimulus GO:0051606 151 96 0,000 0,04372227 0,0439598 ! regulation of DNA metabolic process GO:0051052 178 97 0,000 0,04416822 0,04438962 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,04416822 0,04437108 ! protein ubiquitination GO:0016567 217 97 0,000 0,04416822 0,04435257 ! hormone metabolic process GO:0042445 157 97 0,000 0,04416822 0,04433406 ! regulation of protein localization GO:0032880 176 97 0,000 0,04416822 0,04431557 ! response to virus GO:0009615 160 98 0,000 0,04461398 0,04474416 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,04461398 0,04472552 ! interphase GO:0051325 213 98 0,000 0,04461398 0,04470689 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,04461398 0,04468828 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,04505955 0,0451158 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,04505955 0,04509703 ! skeletal muscle tissue development GO:0007519 186 99 0,000 0,04505955 0,04507828 GO:0060538|skeletal muscle organ development, ! cell cycle arrest GO:0007050 213 100 0,000 0,04550492 0,04550492