pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-b1/out-0.05-06-0.01-300-run-b1//th1-pval-1e-01-08-th2-pval-1e-02-02-th3-pval-1e-01-01-run-b1/go_data/8772-10-real-Sotiriou-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! activation of pro-apoptotic gene products GO:0008633 36 21 2,000 3,264E-07 7,506E-04 ! induction of apoptosis by extracellular signals GO:0008624 74 44 2,000 3,221E-06 3,704E-03 ! regulation of hair follicle development GO:0051797 9 5 1,000 4,314E-06 3,308E-03 GO:0042634|regulation of hair cycle, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 2,000 8,696E-06 5E-03 ! positive regulation of epidermis development GO:0045684 11 7 1,000 9,053E-06 4,165E-03 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 2,000 9,135E-06 3,502E-03 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 2,000 1,054E-05 3,462E-03 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 2,000 1,054E-05 3,03E-03 ! positive regulation of ligase activity GO:0051351 99 69 2,000 1,262E-05 3,225E-03 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 2,000 1,376E-05 3,164E-03 ! regulation of ligase activity GO:0051340 114 75 2,000 1,623E-05 3,393E-03 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 2,000 1,971E-05 3,777E-03 GO:0010498|proteasomal protein catabolic process, ! regulation of epidermis development GO:0045682 17 12 1,000 2,84E-05 5,024E-03 ! induction of apoptosis via death domain receptors GO:0008625 15 13 1,000 3,355E-05 5,512E-03 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 2,000 3,513E-05 5,387E-03 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 1,000 6,568E-05 9,442E-03 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 1,000 9,005E-05 0,01218336 ! cytokine-mediated signaling pathway GO:0019221 76 54 1,000 6,06E-04 0,07742798 ! Golgi vesicle transport GO:0048193 138 85 1,000 1,494E-03 0,18084709 ! interphase of mitotic cell cycle GO:0051329 156 86 1,000 1,529E-03 0,17582827 ! interphase GO:0051325 159 88 1,000 1,6E-03 0,17524788 ! homophilic cell adhesion GO:0007156 149 100 1,000 2,06E-03 0,21532557 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 3,428E-03 0,34277847 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 3,428E-03 0,32849604 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 3,428E-03 0,3153562 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 3,428E-03 0,30322711 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 3,428E-03 0,29199648 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 3,428E-03 0,28156803 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 3,428E-03 0,27185879 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 3,428E-03 0,26279683 ! sleep GO:0030431 11 5 0,000 3,428E-03 0,25431951 ! negative regulation of bone resorption GO:0045779 10 5 0,000 3,428E-03 0,24637203 ! nucleotide-sugar transport GO:0015780 8 5 0,000 3,428E-03 0,23890621 ! regulation of interferon-beta production GO:0032648 5 5 0,000 3,428E-03 0,23187956 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 3,428E-03 0,22525443 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 3,428E-03 0,21899736 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 3,428E-03 0,21307851 ! tongue development GO:0043586 6 5 0,000 3,428E-03 0,20747118 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 3,428E-03 0,20215141 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 3,428E-03 0,19709762 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 3,428E-03 0,19229036 ! cobalt ion transport GO:0006824 9 5 0,000 3,428E-03 0,18771202 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 3,428E-03 0,18334663 ! SMAD protein complex assembly GO:0007183 9 5 0,000 3,428E-03 0,17917966 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 3,428E-03 0,17519789 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 3,428E-03 0,17138924 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 3,428E-03 0,16774266 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 3,428E-03 0,16424802 ! embryonic camera-type eye development GO:0031076 8 5 0,000 3,428E-03 0,16089602 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 3,428E-03 0,1576781 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 3,428E-03 0,15458637 ! adaptation of signaling pathway GO:0022401 7 5 0,000 3,428E-03 0,15161356 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 3,428E-03 0,14875292 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 3,428E-03 0,14599824 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 3,428E-03 0,14334373 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 3,428E-03 0,14078402 ! positive regulation of histone modification GO:0031058 5 5 0,000 3,428E-03 0,13831412 ! malate metabolic process GO:0006108 7 5 0,000 3,428E-03 0,13592939 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 3,428E-03 0,13362551 ! behavioral response to pain GO:0048266 7 5 0,000 3,428E-03 0,13139841 ! clathrin coat assembly GO:0048268 11 5 0,000 3,428E-03 0,12924434 ! phototransduction, visible light GO:0007603 6 5 0,000 3,428E-03 0,12715976 ! regulation of dopamine uptake GO:0051584 9 5 0,000 3,428E-03 0,12514135 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 3,428E-03 0,12318601 ! mating behavior GO:0007617 6 5 0,000 3,428E-03 0,12129084 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 3,428E-03 0,1194531 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 3,428E-03 0,11767022 ! rhythmic behavior GO:0007622 12 5 0,000 3,428E-03 0,11593978 ! copulation GO:0007620 7 5 0,000 3,428E-03 0,11425949 ! glial cell fate commitment GO:0021781 12 5 0,000 3,428E-03 0,11262721 ! protein maturation by protein folding GO:0022417 12 5 0,000 3,428E-03 0,11104091 ! embryonic hemopoiesis GO:0035162 10 5 0,000 3,428E-03 0,10949868 ! regulation of potassium ion transport GO:0043266 9 5 0,000 3,428E-03 0,1079987 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 3,428E-03 0,10653926 ! apoptotic cell clearance GO:0043277 13 5 0,000 3,428E-03 0,10511873 ! lipoprotein particle clearance GO:0034381 9 5 0,000 3,428E-03 0,10373559 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 3,428E-03 0,10238838 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 3,428E-03 0,1010757 ! response to protozoan GO:0001562 9 5 0,000 3,428E-03 0,09979626 ! positive regulation of glycolysis GO:0045821 11 5 0,000 3,428E-03 0,09854881 ! lymph vessel development GO:0001945 7 5 0,000 3,428E-03 0,09733216 ! endochondral ossification GO:0001958 12 5 0,000 3,428E-03 0,09614518 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 3,428E-03 0,09498681 ! parathyroid gland development GO:0060017 8 5 0,000 3,428E-03 0,09385601 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 3,428E-03 0,09275182 ! anagen GO:0042640 6 5 0,000 3,428E-03 0,09167331 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 3,428E-03 0,0906196 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 3,428E-03 0,08958983 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 3,428E-03 0,0885832 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 3,428E-03 0,08759894 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 3,428E-03 0,08663632 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 3,428E-03 0,08569462 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 3,428E-03 0,08477317 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 3,428E-03 0,08387133 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 3,428E-03 0,08298847 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 3,428E-03 0,08212401 ! cardiac muscle fiber development GO:0048739 7 5 0,000 3,428E-03 0,08127737 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 3,428E-03 0,08044801 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 3,428E-03 0,0796354 ! neutrophil mediated immunity GO:0002446 6 5 0,000 3,428E-03 0,07883905 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 3,428E-03 0,07805846 ! ovulation GO:0030728 6 5 0,000 3,428E-03 0,07729319 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 3,428E-03 0,07654277 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 3,428E-03 0,07580678 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 3,428E-03 0,07508481 ! response to pH GO:0009268 9 5 0,000 3,428E-03 0,07437646 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 3,428E-03 0,07368135 ! proline biosynthetic process GO:0006561 6 5 0,000 3,428E-03 0,07299912 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 3,428E-03 0,0723294 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 3,428E-03 0,07167186 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 3,428E-03 0,07102617 ! polyol catabolic process GO:0046174 7 5 0,000 3,428E-03 0,07039201 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 3,428E-03 0,06976907 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 3,428E-03 0,06915706 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 3,428E-03 0,06855569 ! sister chromatid cohesion GO:0007062 9 5 0,000 3,428E-03 0,0679647 ! nerve growth factor processing GO:0032455 7 5 0,000 3,428E-03 0,0673838 ! urea metabolic process GO:0019627 6 5 0,000 3,428E-03 0,06681275 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 3,428E-03 0,0662513 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 3,428E-03 0,06569921 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 3,428E-03 0,06515624 ! neutrophil activation GO:0042119 5 5 0,000 3,428E-03 0,06462217 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 3,428E-03 0,06409679 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 3,428E-03 0,06357988 ! response to food GO:0032094 5 5 0,000 3,428E-03 0,06307124 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 3,428E-03 0,06257067 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 3,428E-03 0,06207799 ! paraxial mesoderm development GO:0048339 9 5 0,000 3,428E-03 0,06159301 ! forebrain neuron development GO:0021884 7 5 0,000 3,428E-03 0,06111554 ! melanosome organization GO:0032438 7 5 0,000 3,428E-03 0,06064542 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 3,428E-03 0,06018248 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 3,428E-03 0,05972655 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 3,428E-03 0,05927748 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 3,428E-03 0,05883511 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 3,428E-03 0,0583993 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 3,428E-03 0,05796989 ! nucleoside transport GO:0015858 6 5 0,000 3,428E-03 0,05754675 ! nucleoside salvage GO:0043174 7 5 0,000 3,428E-03 0,05712975 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 3,428E-03 0,05671874 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 3,428E-03 0,05631361 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 3,428E-03 0,05591422 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 3,428E-03 0,05552046 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 3,428E-03 0,0551322 ! early endosome to late endosome transport GO:0045022 11 5 0,000 3,428E-03 0,05474934 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 3,428E-03 0,05437176 ! depyrimidination GO:0045008 8 5 0,000 3,428E-03 0,05399935 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 3,428E-03 0,05363201 ! 5S class rRNA transcription GO:0042791 8 5 0,000 3,428E-03 0,05326963 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 3,428E-03 0,05291211 ! regulation of centrosome cycle GO:0046605 7 5 0,000 3,428E-03 0,05255937 ! neuronal ion channel clustering GO:0045161 7 5 0,000 3,428E-03 0,05221129 ! sodium ion homeostasis GO:0055078 6 5 0,000 3,428E-03 0,0518678 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 3,428E-03 0,05152879 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 3,428E-03 0,05119419 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 3,428E-03 0,0508639 ! monocyte differentiation GO:0030224 8 5 0,000 3,428E-03 0,05053785 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 3,428E-03 0,05021595 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 3,428E-03 0,04989813 ! centrosome duplication GO:0051298 5 5 0,000 3,428E-03 0,04958431 ! response to UV-C GO:0010225 6 5 0,000 3,428E-03 0,04927441 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 3,428E-03 0,04896835 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 3,428E-03 0,04866608 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 3,428E-03 0,04836751 ! regulation of dendrite development GO:0050773 12 5 0,000 3,428E-03 0,04807259 ! peptidyl-arginine modification GO:0018195 7 5 0,000 3,428E-03 0,04778124 ! positive regulation of organ growth GO:0046622 6 5 0,000 3,428E-03 0,0474934 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 3,428E-03 0,04720901 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 3,428E-03 0,04692801 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 3,428E-03 0,04665032 ! regulation of dopamine secretion GO:0014059 12 5 0,000 3,428E-03 0,04637591 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 3,428E-03 0,04610471 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 3,428E-03 0,04583666 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 3,428E-03 0,0455717 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 3,428E-03 0,0453098 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 3,428E-03 0,04505089 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 3,428E-03 0,04479491 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 3,428E-03 0,04454184 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 3,428E-03 0,0442916 ! neural tube patterning GO:0021532 6 5 0,000 3,428E-03 0,04404416 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 3,428E-03 0,04379947 ! histone demethylation GO:0016577 9 5 0,000 3,428E-03 0,04355749 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 3,428E-03 0,04331816 ! regulation of sterol transport GO:0032371 7 5 0,000 3,428E-03 0,04308145 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 3,428E-03 0,04284731 ! enteric nervous system development GO:0048484 8 5 0,000 3,428E-03 0,0426157 ! establishment of planar polarity GO:0001736 6 5 0,000 3,428E-03 0,04238659 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 3,428E-03 0,04215992 ! muscle cell proliferation GO:0033002 8 5 0,000 3,428E-03 0,04193566 ! transcription termination GO:0006353 8 5 0,000 3,428E-03 0,04171378 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 3,428E-03 0,04149424 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 3,428E-03 0,04127699 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 3,428E-03 0,041062 ! regulation of respiratory burst GO:0060263 8 5 0,000 3,428E-03 0,04084925 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 3,428E-03 0,04063868 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 3,428E-03 0,04043028 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 3,428E-03 0,040224 GO:0015991|ATP hydrolysis coupled proton transport, ! protein destabilization GO:0031648 6 5 0,000 3,428E-03 0,04001982 ! apical protein localization GO:0045176 6 5 0,000 3,428E-03 0,0398177 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 3,428E-03 0,03961761 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 3,428E-03 0,03941952 ! galactolipid metabolic process GO:0019374 7 5 0,000 3,428E-03 0,03922341 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 3,428E-03 0,03902923 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 3,428E-03 0,03883697 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 3,428E-03 0,03864659 ! triglyceride catabolic process GO:0019433 6 5 0,000 3,428E-03 0,03845807 ! glial cell migration GO:0008347 10 5 0,000 3,428E-03 0,03827138 ! determination of adult lifespan GO:0008340 8 5 0,000 3,428E-03 0,0380865 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 3,428E-03 0,03790339 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 3,428E-03 0,03772203 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 3,428E-03 0,0375424 ! somatic stem cell maintenance GO:0035019 13 5 0,000 3,428E-03 0,03736448 ! cerebellar cortex formation GO:0021697 6 5 0,000 3,428E-03 0,03718823 ! neural plate development GO:0001840 6 5 0,000 3,428E-03 0,03701364 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 3,428E-03 0,03684068 ! regulation of sensory perception GO:0051931 6 5 0,000 3,428E-03 0,03666933 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 3,428E-03 0,03649956 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 3,428E-03 0,03633136 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 3,428E-03 0,0361647 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 3,428E-03 0,03599957 ! sensory cilium assembly GO:0035058 6 5 0,000 3,428E-03 0,03583593 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 3,428E-03 0,03567378 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 3,428E-03 0,03551309 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 3,428E-03 0,03535383 ! spindle assembly GO:0051225 5 5 0,000 3,428E-03 0,035196 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 3,428E-03 0,03503958 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 3,428E-03 0,03488453 ! protein amino acid prenylation GO:0018346 9 5 0,000 3,428E-03 0,03473086 ! organ regeneration GO:0031100 7 5 0,000 3,428E-03 0,03457853 ! NAD biosynthetic process GO:0009435 7 5 0,000 3,428E-03 0,03442753 ! carnitine metabolic process GO:0009437 5 5 0,000 3,428E-03 0,03427785 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 3,428E-03 0,03412946 ! cellular anion homeostasis GO:0030002 6 5 0,000 3,428E-03 0,03398235 GO:0055081|anion homeostasis, ! tRNA transcription GO:0009304 11 6 0,000 4,112E-03 0,04059103 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 4,112E-03 0,04041756 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 4,112E-03 0,04024557 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 4,112E-03 0,04007504 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 4,112E-03 0,03990595 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 4,112E-03 0,03973828 ! regulation of helicase activity GO:0051095 11 6 0,000 4,112E-03 0,03957201 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 4,112E-03 0,03940713 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 4,112E-03 0,03924361 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 4,112E-03 0,03908145 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 4,112E-03 0,03892062 ! positive regulation of axon extension GO:0045773 8 6 0,000 4,112E-03 0,03876111 ! prostate gland development GO:0030850 9 6 0,000 4,112E-03 0,0386029 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 4,112E-03 0,03844598 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 4,112E-03 0,03829032 ! forebrain neuron differentiation GO:0021879 9 6 0,000 4,112E-03 0,03813593 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 4,112E-03 0,03798277 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 4,112E-03 0,03783084 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 4,112E-03 0,03768012 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 4,112E-03 0,0375306 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 4,112E-03 0,03738225 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 4,112E-03 0,03723508 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 4,112E-03 0,03708906 ! neuron adhesion GO:0007158 9 6 0,000 4,112E-03 0,03694418 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 4,112E-03 0,03680043 ! establishment of tissue polarity GO:0007164 7 6 0,000 4,112E-03 0,03665779 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 4,112E-03 0,03651626 ! signal peptide processing GO:0006465 8 6 0,000 4,112E-03 0,03637581 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 4,112E-03 0,03623644 ! mRNA stabilization GO:0048255 15 6 0,000 4,112E-03 0,03609813 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 4,112E-03 0,03596087 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 4,112E-03 0,03582466 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 4,112E-03 0,03568947 ! opsonization GO:0008228 8 6 0,000 4,112E-03 0,0355553 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 4,112E-03 0,03542214 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 4,112E-03 0,03528996 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 4,112E-03 0,03515877 ! protein amino acid dealkylation GO:0008214 11 6 0,000 4,112E-03 0,03502856 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 4,112E-03 0,0348993 ! photoreceptor cell development GO:0042461 10 6 0,000 4,112E-03 0,03477099 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 4,112E-03 0,03464363 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 4,112E-03 0,03451719 ! mechanosensory behavior GO:0007638 8 6 0,000 4,112E-03 0,03439167 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 4,112E-03 0,03426707 ! negative regulation of endocytosis GO:0045806 8 6 0,000 4,112E-03 0,03414336 ! response to interferon-gamma GO:0034341 12 6 0,000 4,112E-03 0,03402054 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 4,112E-03 0,0338986 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 4,112E-03 0,03377754 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 4,112E-03 0,03365733 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 4,112E-03 0,03353798 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 4,112E-03 0,03341947 ! cGMP-mediated signaling GO:0019934 10 6 0,000 4,112E-03 0,0333018 ! activation of MAPKKK activity GO:0000185 10 6 0,000 4,112E-03 0,03318495 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 4,112E-03 0,03306892 ! thymic T cell selection GO:0045061 12 6 0,000 4,112E-03 0,03295369 ! protein lipoylation GO:0009249 10 6 0,000 4,112E-03 0,03283927 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 4,112E-03 0,03272564 ! pigment granule organization GO:0048753 11 6 0,000 4,112E-03 0,03261279 ! drug transport GO:0015893 6 6 0,000 4,112E-03 0,03250072 ! cysteine metabolic process GO:0006534 7 6 0,000 4,112E-03 0,03238942 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 4,112E-03 0,03227887 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 4,112E-03 0,03216908 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 4,112E-03 0,03206003 ! histidine metabolic process GO:0006547 6 6 0,000 4,112E-03 0,03195172 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 4,112E-03 0,03184414 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 4,112E-03 0,03173728 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 4,112E-03 0,03163114 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 4,112E-03 0,0315257 ! adenohypophysis development GO:0021984 10 6 0,000 4,112E-03 0,03142096 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 4,112E-03 0,03131692 ! hyperosmotic response GO:0006972 8 6 0,000 4,112E-03 0,03121356 ! microtubule nucleation GO:0007020 10 6 0,000 4,112E-03 0,03111089 ! ER overload response GO:0006983 7 6 0,000 4,112E-03 0,03100889 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 4,112E-03 0,03090755 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 4,112E-03 0,03080687 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 4,112E-03 0,03070685 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 4,112E-03 0,03060748 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 4,112E-03 0,03050874 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 4,112E-03 0,03041064 ! response to dietary excess GO:0002021 7 6 0,000 4,112E-03 0,03031317 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 4,112E-03 0,03021633 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 4,112E-03 0,0301201 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 4,112E-03 0,03002448 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 4,112E-03 0,02992946 ! glycerol ether catabolic process GO:0044269 8 6 0,000 4,112E-03 0,02983505 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 4,112E-03 0,02974123 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 4,112E-03 0,02964799 ! neuron apoptosis GO:0051402 8 6 0,000 4,112E-03 0,02955534 ! organic alcohol transport GO:0015850 9 6 0,000 4,112E-03 0,02946327 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 4,112E-03 0,02937177 ! T cell mediated immunity GO:0002456 12 6 0,000 4,112E-03 0,02928084 ! male sex determination GO:0030238 9 6 0,000 4,112E-03 0,02919046 ! carnitine transport GO:0015879 8 6 0,000 4,112E-03 0,02910065 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 4,112E-03 0,02901138 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 4,112E-03 0,02892266 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 4,112E-03 0,02883448 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 4,112E-03 0,02874684 ! positive regulation of exocytosis GO:0045921 6 6 0,000 4,112E-03 0,02865973 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 4,112E-03 0,02857314 ! parturition GO:0007567 12 6 0,000 4,112E-03 0,02848708 ! negative regulation of translational initiation GO:0045947 7 6 0,000 4,112E-03 0,02840153 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 4,112E-03 0,0283165 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 4,112E-03 0,02823197 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 4,112E-03 0,02814795 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 4,112E-03 0,02806442 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 4,112E-03 0,02798139 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 4,112E-03 0,02789885 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 4,112E-03 0,02781679 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 4,112E-03 0,02773522 ! macrophage differentiation GO:0030225 10 6 0,000 4,112E-03 0,02765412 ! astrocyte development GO:0014002 14 6 0,000 4,112E-03 0,0275735 ! hyaluronan metabolic process GO:0030212 6 6 0,000 4,112E-03 0,02749334 ! purine base biosynthetic process GO:0009113 14 6 0,000 4,112E-03 0,02741365 ! interaction with symbiont GO:0051702 8 6 0,000 4,112E-03 0,02733442 ! anterograde axon cargo transport GO:0008089 8 6 0,000 4,112E-03 0,02725565 ! skeletal muscle contraction GO:0003009 6 6 0,000 4,112E-03 0,02717733 ! eating behavior GO:0042755 6 6 0,000 4,112E-03 0,02709946 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 4,112E-03 0,02702203 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 4,112E-03 0,02694504 ! response to copper ion GO:0046688 9 6 0,000 4,112E-03 0,02686849 ! DNA topological change GO:0006265 8 6 0,000 4,112E-03 0,02679238 ! response to exogenous dsRNA GO:0043330 8 6 0,000 4,112E-03 0,0267167 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 4,112E-03 0,02664144 ! establishment of melanosome localization GO:0032401 9 6 0,000 4,112E-03 0,0265666 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 4,112E-03 0,02649219 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 4,112E-03 0,02641818 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 4,112E-03 0,0263446 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 4,112E-03 0,02627142 ! nucleoside catabolic process GO:0009164 6 6 0,000 4,112E-03 0,02619864 ! gas homeostasis GO:0033483 11 6 0,000 4,112E-03 0,02612627 ! hair follicle maturation GO:0048820 7 6 0,000 4,112E-03 0,0260543 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 4,112E-03 0,02598272 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 4,112E-03 0,02591153 ! Schwann cell development GO:0014044 14 6 0,000 4,112E-03 0,02584074 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 4,112E-03 0,02577033 ! dendrite morphogenesis GO:0048813 9 6 0,000 4,112E-03 0,0257003 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 4,112E-03 0,02563065 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 4,112E-03 0,02556138 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 4,112E-03 0,02549248 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 4,112E-03 0,02542395 ! histone ubiquitination GO:0016574 7 6 0,000 4,112E-03 0,02535579 ! regulation of meiosis GO:0040020 10 6 0,000 4,112E-03 0,02528799 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 4,112E-03 0,02522056 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 4,112E-03 0,02515348 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 4,112E-03 0,02508676 ! regulation of mast cell activation GO:0033003 6 6 0,000 4,112E-03 0,0250204 ! membrane to membrane docking GO:0022614 12 6 0,000 4,112E-03 0,02495438 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 4,112E-03 0,02488871 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 4,112E-03 0,02482339 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 4,112E-03 0,0247584 ! receptor internalization GO:0031623 9 6 0,000 4,112E-03 0,02469376 ! neutrophil homeostasis GO:0001780 6 6 0,000 4,112E-03 0,02462945 ! coenzyme A metabolic process GO:0015936 9 6 0,000 4,112E-03 0,02456548 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 4,112E-03 0,02450184 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 4,112E-03 0,02443853 ! protein deubiquitination GO:0016579 8 6 0,000 4,112E-03 0,02437554 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 4,112E-03 0,02431288 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 4,112E-03 0,02425054 ! peptidyl-histidine modification GO:0018202 9 6 0,000 4,112E-03 0,02418852 ! axonal fasciculation GO:0007413 9 6 0,000 4,112E-03 0,02412681 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 4,112E-03 0,02406542 ! thiamin metabolic process GO:0006772 6 6 0,000 4,112E-03 0,02400434 ! midbrain development GO:0030901 6 6 0,000 4,112E-03 0,02394357 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 4,112E-03 0,02388311 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 4,112E-03 0,02382295 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 4,112E-03 0,02376309 ! progesterone metabolic process GO:0042448 8 6 0,000 4,112E-03 0,02370353 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 4,112E-03 0,02364428 ! glycolipid catabolic process GO:0019377 13 6 0,000 4,112E-03 0,02358531 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 4,112E-03 0,02352664 ! positive regulation of glucose import GO:0046326 6 6 0,000 4,112E-03 0,02346826 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 4,112E-03 0,02341017 ! adult feeding behavior GO:0008343 6 6 0,000 4,112E-03 0,02335237 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 4,112E-03 0,02329485 ! blastocyst growth GO:0001832 15 6 0,000 4,112E-03 0,02323762 ! pigment granule transport GO:0051904 12 6 0,000 4,112E-03 0,02318066 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 4,112E-03 0,02312399 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 4,112E-03 0,02306759 ! catecholamine transport GO:0051937 7 6 0,000 4,112E-03 0,02301146 ! organ or tissue specific immune response GO:0002251 7 6 0,000 4,112E-03 0,02295561 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 4,112E-03 0,02290002 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 4,112E-03 0,02284471 ! negative regulation of B cell activation GO:0050869 9 6 0,000 4,112E-03 0,02278966 ! protein prenylation GO:0018342 10 6 0,000 4,112E-03 0,02273488 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 4,112E-03 0,02268036 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 4,112E-03 0,0226261 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 4,112E-03 0,0225721 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 4,112E-03 0,02251836 ! positive regulation of coagulation GO:0050820 11 6 0,000 4,112E-03 0,02246487 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 0,000 4,796E-03 0,02613868 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 4,796E-03 0,02607689 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 4,796E-03 0,02601539 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 4,796E-03 0,02595418 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 4,796E-03 0,02589325 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 4,796E-03 0,02583261 ! synaptonemal complex assembly GO:0007130 10 7 0,000 4,796E-03 0,02577225 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 4,796E-03 0,02571218 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 4,796E-03 0,02565238 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 4,796E-03 0,02559286 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 4,796E-03 0,02553362 ! reproductive behavior GO:0019098 12 7 0,000 4,796E-03 0,02547465 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 4,796E-03 0,02541596 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 4,796E-03 0,02535753 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 4,796E-03 0,02529937 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 4,796E-03 0,02524148 ! oligopeptide transport GO:0006857 11 7 0,000 4,796E-03 0,02518385 ! protein amino acid sulfation GO:0006477 9 7 0,000 4,796E-03 0,02512648 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 4,796E-03 0,02506937 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 4,796E-03 0,02501253 ! RNA methylation GO:0001510 11 7 0,000 4,796E-03 0,02495594 ! pericardium development GO:0060039 8 7 0,000 4,796E-03 0,0248996 ! macrophage chemotaxis GO:0048246 10 7 0,000 4,796E-03 0,02484352 ! fibril organization GO:0043206 13 7 0,000 4,796E-03 0,0247877 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 4,796E-03 0,02473212 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 4,796E-03 0,02467679 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 4,796E-03 0,02462171 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 4,796E-03 0,02456687 ! lipoprotein transport GO:0042953 9 7 0,000 4,796E-03 0,02451228 ! cerebral cortex cell migration GO:0021795 11 7 0,000 4,796E-03 0,02445793 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 4,796E-03 0,02440382 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 4,796E-03 0,02434994 ! estrogen metabolic process GO:0008210 14 7 0,000 4,796E-03 0,02429631 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 4,796E-03 0,02424291 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 4,796E-03 0,02418975 ! chemosensory behavior GO:0007635 9 7 0,000 4,796E-03 0,02413682 ! microtubule bundle formation GO:0001578 8 7 0,000 4,796E-03 0,02408411 ! T-helper 1 type immune response GO:0042088 11 7 0,000 4,796E-03 0,02403164 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 4,796E-03 0,0239794 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 4,796E-03 0,02392739 ! leukocyte degranulation GO:0043299 10 7 0,000 4,796E-03 0,02387559 ! bile acid and bile salt transport GO:0015721 9 7 0,000 4,796E-03 0,02382403 ! reflex GO:0060004 12 7 0,000 4,796E-03 0,02377268 ! positive regulation of isotype switching GO:0045830 15 7 0,000 4,796E-03 0,02372156 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 4,796E-03 0,02367065 ! protein-cofactor linkage GO:0018065 13 7 0,000 4,796E-03 0,02361997 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 4,796E-03 0,0235695 ! glycerolipid catabolic process GO:0046503 9 7 0,000 4,796E-03 0,02351924 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 4,796E-03 0,0234692 ! spinal cord patterning GO:0021511 7 7 0,000 4,796E-03 0,02341937 ! hemoglobin metabolic process GO:0020027 10 7 0,000 4,796E-03 0,02336976 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 4,796E-03 0,02332035 ! adrenal gland development GO:0030325 17 7 0,000 4,796E-03 0,02327115 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 4,796E-03 0,02322216 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 4,796E-03 0,02317337 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 4,796E-03 0,02312479 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 4,796E-03 0,02307641 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 4,796E-03 0,02302824 ! endosome organization GO:0007032 10 7 0,000 4,796E-03 0,02298026 ! thyroid hormone generation GO:0006590 11 7 0,000 4,796E-03 0,02293248 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 4,796E-03 0,02288491 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 4,796E-03 0,02283753 ! regulation of pigmentation during development GO:0048070 15 7 0,000 4,796E-03 0,02279034 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 4,796E-03 0,02274335 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 4,796E-03 0,02269655 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 4,796E-03 0,02264995 ! galactose metabolic process GO:0006012 10 7 0,000 4,796E-03 0,02260353 ! vesicle fusion GO:0006906 15 7 0,000 4,796E-03 0,02255731 ! intracellular pH reduction GO:0051452 10 7 0,000 4,796E-03 0,02251127 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 4,796E-03 0,02246543 ! organ growth GO:0035265 11 7 0,000 4,796E-03 0,02241977 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 4,796E-03 0,02237429 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 4,796E-03 0,022329 ! Rac protein signal transduction GO:0016601 7 7 0,000 4,796E-03 0,02228389 ! retinol metabolic process GO:0042572 9 7 0,000 4,796E-03 0,02223896 ! behavioral fear response GO:0001662 13 7 0,000 4,796E-03 0,02219421 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 4,796E-03 0,02214965 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 4,796E-03 0,02210526 ! rRNA modification GO:0000154 12 7 0,000 4,796E-03 0,02206105 ! protein heterooligomerization GO:0051291 10 7 0,000 4,796E-03 0,02201702 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 4,796E-03 0,02197316 ! response to UV-B GO:0010224 11 7 0,000 4,796E-03 0,02192947 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 4,796E-03 0,02188596 ! protein retention in ER lumen GO:0006621 12 7 0,000 4,796E-03 0,02184262 ! intermediate filament organization GO:0045109 11 7 0,000 4,796E-03 0,02179946 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 4,796E-03 0,02175646 ! cardiac muscle cell development GO:0055013 9 7 0,000 4,796E-03 0,02171363 ! fibrinolysis GO:0042730 9 7 0,000 4,796E-03 0,02167097 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 4,796E-03 0,02162848 ! regulation of circadian rhythm GO:0042752 11 7 0,000 4,796E-03 0,02158615 ! B cell lineage commitment GO:0002326 17 7 0,000 4,796E-03 0,02154399 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 4,796E-03 0,021502 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 4,796E-03 0,02146016 ! response to tropane GO:0014073 13 7 0,000 4,796E-03 0,02141849 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 4,796E-03 0,02137699 ! melanosome localization GO:0032400 10 7 0,000 4,796E-03 0,02133564 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 4,796E-03 0,02129445 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 4,796E-03 0,02125342 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 4,796E-03 0,02121255 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 4,796E-03 0,02117183 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 4,796E-03 0,02113127 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 4,796E-03 0,02109087 ! mast cell activation GO:0045576 9 7 0,000 4,796E-03 0,02105062 ! multicellular organismal aging GO:0010259 11 7 0,000 4,796E-03 0,02101052 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 4,796E-03 0,02097058 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 4,796E-03 0,02093079 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 4,796E-03 0,02089115 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 4,796E-03 0,02085165 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 4,796E-03 0,02081231 ! establishment of nucleus localization GO:0040023 13 7 0,000 4,796E-03 0,02077312 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 4,796E-03 0,02073407 ! T cell lineage commitment GO:0002360 12 7 0,000 4,796E-03 0,02069517 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 4,796E-03 0,02065641 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 4,796E-03 0,0206178 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 4,796E-03 0,02057934 ! regulation of lipid transport GO:0032368 13 7 0,000 4,796E-03 0,02054101 ! response to tumor cell GO:0002347 12 7 0,000 4,796E-03 0,02050283 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 4,796E-03 0,0204648 ! neuroblast proliferation GO:0007405 13 7 0,000 4,796E-03 0,0204269 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 4,796E-03 0,02038914 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 4,796E-03 0,02035152 ! peptidyl-threonine modification GO:0018210 18 7 0,000 4,796E-03 0,02031404 ! diuresis GO:0030146 12 7 0,000 4,796E-03 0,0202767 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 4,796E-03 0,02023949 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 4,796E-03 0,02020243 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 4,796E-03 0,02016549 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 4,796E-03 0,02012869 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 4,796E-03 0,02009203 ! melanin biosynthetic process GO:0042438 8 7 0,000 4,796E-03 0,0200555 ! regulation of synaptogenesis GO:0051963 10 7 0,000 4,796E-03 0,0200191 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 4,796E-03 0,01998283 ! dopamine biosynthetic process GO:0042416 15 7 0,000 4,796E-03 0,0199467 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 4,796E-03 0,01991069 ! lymph node development GO:0048535 9 7 0,000 4,796E-03 0,01987482 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 4,796E-03 0,01983907 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 4,796E-03 0,01980346 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 4,796E-03 0,01976797 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 4,796E-03 0,0197326 ! endosome to lysosome transport GO:0008333 10 7 0,000 4,796E-03 0,01969737 ! ATP catabolic process GO:0006200 10 7 0,000 4,796E-03 0,01966225 ! establishment of pigment granule localization GO:0051905 13 7 0,000 4,796E-03 0,01962727 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 4,796E-03 0,01959241 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 4,796E-03 0,01955767 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 4,796E-03 0,01952305 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 4,796E-03 0,01948856 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 4,796E-03 0,01945419 ! muscle adaptation GO:0043500 12 7 0,000 4,796E-03 0,01941994 ! amino sugar catabolic process GO:0046348 9 7 0,000 4,796E-03 0,01938581 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 4,796E-03 0,0193518 ! retina homeostasis GO:0001895 9 7 0,000 4,796E-03 0,01931791 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 4,796E-03 0,01928413 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 4,796E-03 0,01925048 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 4,796E-03 0,01921694 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 4,796E-03 0,01918352 ! behavioral response to nicotine GO:0035095 11 7 0,000 4,796E-03 0,01915022 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 4,796E-03 0,01911703 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 4,796E-03 0,01908395 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 5,479E-03 0,02176572 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 5,479E-03 0,02172819 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 5,479E-03 0,02169079 ! axon extension GO:0048675 11 8 0,000 5,479E-03 0,02165352 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 5,479E-03 0,02161638 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 5,479E-03 0,02157937 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 5,479E-03 0,02154248 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 5,479E-03 0,02150572 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 5,479E-03 0,02146908 ! cell proliferation in forebrain GO:0021846 10 8 0,000 5,479E-03 0,02143257 ! positive regulation of B cell proliferation GO:0030890 11 8 0,000 5,479E-03 0,02139618 ! phosphate transport GO:0006817 10 8 0,000 5,479E-03 0,02135991 ! N-glycan processing GO:0006491 12 8 0,000 5,479E-03 0,02132377 ! Golgi to endosome transport GO:0006895 16 8 0,000 5,479E-03 0,02128775 ! UTP metabolic process GO:0046051 8 8 0,000 5,479E-03 0,02125185 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 5,479E-03 0,02121608 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 5,479E-03 0,02118042 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 5,479E-03 0,02114488 ! neurotransmitter uptake GO:0001504 10 8 0,000 5,479E-03 0,02110946 ! succinate metabolic process GO:0006105 14 8 0,000 5,479E-03 0,02107416 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 5,479E-03 0,02103898 ! smoothened signaling pathway GO:0007224 8 8 0,000 5,479E-03 0,02100392 ! membrane hyperpolarization GO:0060081 10 8 0,000 5,479E-03 0,02096897 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 5,479E-03 0,02093413 ! keratinocyte proliferation GO:0043616 12 8 0,000 5,479E-03 0,02089942 ! middle ear morphogenesis GO:0042474 9 8 0,000 5,479E-03 0,02086482 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 5,479E-03 0,02083033 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 5,479E-03 0,02079596 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 5,479E-03 0,0207617 ! ganglioside metabolic process GO:0001573 15 8 0,000 5,479E-03 0,02072755 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 5,479E-03 0,02069351 ! pseudouridine synthesis GO:0001522 9 8 0,000 5,479E-03 0,02065959 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 5,479E-03 0,02062578 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 5,479E-03 0,02059207 ! endothelial cell differentiation GO:0045446 14 8 0,000 5,479E-03 0,02055848 ! ceramide biosynthetic process GO:0046513 9 8 0,000 5,479E-03 0,020525 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 5,479E-03 0,02049162 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 0,000 5,479E-03 0,02045836 ! astrocyte differentiation GO:0048708 16 8 0,000 5,479E-03 0,0204252 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 5,479E-03 0,02039215 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 5,479E-03 0,02035921 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 5,479E-03 0,02032637 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 5,479E-03 0,02029364 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 5,479E-03 0,02026101 ! melanin metabolic process GO:0006582 12 8 0,000 5,479E-03 0,02022849 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 5,479E-03 0,02019607 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 5,479E-03 0,02016376 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 5,479E-03 0,02013155 ! macrophage activation GO:0042116 12 8 0,000 5,479E-03 0,02009944 ! regulation of type I interferon production GO:0032479 8 8 0,000 5,479E-03 0,02006743 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 5,479E-03 0,02003553 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 5,479E-03 0,02000373 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 5,479E-03 0,01997203 ! regulation of vascular permeability GO:0043114 12 8 0,000 5,479E-03 0,01994043 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 5,479E-03 0,01990892 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 5,479E-03 0,01987752 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 5,479E-03 0,01984622 ! ruffle organization GO:0031529 11 8 0,000 5,479E-03 0,01981501 ! osteoblast development GO:0002076 13 8 0,000 5,479E-03 0,01978391 ! lens development in camera-type eye GO:0002088 10 8 0,000 5,479E-03 0,0197529 ! positive regulation of vasodilation GO:0045909 12 8 0,000 5,479E-03 0,01972199 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 5,479E-03 0,01969117 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 5,479E-03 0,01966045 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 5,479E-03 0,01962983 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 5,479E-03 0,0195993 ! Schwann cell differentiation GO:0014037 17 8 0,000 5,479E-03 0,01956887 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 5,479E-03 0,01953853 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 5,479E-03 0,01950828 ! regulation of gliogenesis GO:0014013 20 8 0,000 5,479E-03 0,01947813 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 5,479E-03 0,01944807 ! oligodendrocyte development GO:0014003 8 8 0,000 5,479E-03 0,0194181 ! segment specification GO:0007379 10 8 0,000 5,479E-03 0,01938823 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 5,479E-03 0,01935845 ! cellular extravasation GO:0045123 11 8 0,000 5,479E-03 0,01932876 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 5,479E-03 0,01929916 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 5,479E-03 0,01926965 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 5,479E-03 0,01924023 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 5,479E-03 0,0192109 ! snRNA metabolic process GO:0016073 10 8 0,000 5,479E-03 0,01918166 GO:0016180|snRNA processing, ! phosphoinositide 3-kinase cascade GO:0014065 23 8 0,000 5,479E-03 0,01915251 ! regulation of interleukin-4 production GO:0032673 16 8 0,000 5,479E-03 0,01912344 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 5,479E-03 0,01909447 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 5,479E-03 0,01906558 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 5,479E-03 0,01903678 ! nucleosome disassembly GO:0006337 12 8 0,000 5,479E-03 0,01900807 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 5,479E-03 0,01897944 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 5,479E-03 0,0189509 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 5,479E-03 0,01892245 ! icosanoid secretion GO:0032309 12 8 0,000 5,479E-03 0,01889408 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 5,479E-03 0,01886579 ! leukocyte activation during immune response GO:0002366 13 8 0,000 5,479E-03 0,01883759 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 5,479E-03 0,01880948 ! cerebellum morphogenesis GO:0021587 9 8 0,000 5,479E-03 0,01878144 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 5,479E-03 0,0187535 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 5,479E-03 0,01872563 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 5,479E-03 0,01869785 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 5,479E-03 0,01867015 ! sterol catabolic process GO:0016127 9 8 0,000 5,479E-03 0,01864253 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 5,479E-03 0,01861499 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 5,479E-03 0,01858754 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 5,479E-03 0,01856016 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 5,479E-03 0,01853287 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 5,479E-03 0,01850565 ! prophase GO:0051324 11 8 0,000 5,479E-03 0,01847852 ! S phase GO:0051320 8 8 0,000 5,479E-03 0,01845146 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 5,479E-03 0,01842449 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 5,479E-03 0,01839759 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 5,479E-03 0,01837077 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 5,479E-03 0,01834403 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 5,479E-03 0,01831737 ! hormone catabolic process GO:0042447 13 8 0,000 5,479E-03 0,01829078 ! quaternary ammonium group transport GO:0015697 10 8 0,000 5,479E-03 0,01826427 ! myeloid cell homeostasis GO:0002262 8 8 0,000 5,479E-03 0,01823784 ! regulation of fibrinolysis GO:0051917 13 8 0,000 5,479E-03 0,01821149 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 5,479E-03 0,01818521 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 5,479E-03 0,018159 ! regulation of telomere maintenance GO:0032204 10 8 0,000 5,479E-03 0,01813288 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 5,479E-03 0,01810682 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 5,479E-03 0,01808085 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 5,479E-03 0,01805494 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 5,479E-03 0,01802911 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 5,479E-03 0,01800336 ! lamellipodium assembly GO:0030032 9 8 0,000 5,479E-03 0,01797767 ! regulation of embryonic development GO:0045995 16 8 0,000 5,479E-03 0,01795206 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 5,479E-03 0,01792653 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 5,479E-03 0,01790106 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 5,479E-03 0,01787567 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 6,162E-03 0,02007533 ! regulation of developmental growth GO:0048638 13 9 0,000 6,162E-03 0,02004694 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 6,162E-03 0,02001862 ! telencephalon cell migration GO:0022029 16 9 0,000 6,162E-03 0,01999039 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 6,162E-03 0,01996223 ! pentose-phosphate shunt GO:0006098 12 9 0,000 6,162E-03 0,01993416 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 6,162E-03 0,01990616 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 6,162E-03 0,01987824 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 6,162E-03 0,0198504 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 6,162E-03 0,01982264 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 6,162E-03 0,01979495 ! GTP metabolic process GO:0046039 9 9 0,000 6,162E-03 0,01976734 ! elastic fiber assembly GO:0048251 13 9 0,000 6,162E-03 0,01973981 ! social behavior GO:0035176 14 9 0,000 6,162E-03 0,01971236 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 6,162E-03 0,01968498 ! artery development GO:0060840 19 9 0,000 6,162E-03 0,01965768 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 6,162E-03 0,01963045 ! regulation of glycolysis GO:0006110 15 9 0,000 6,162E-03 0,0196033 ! response to pain GO:0048265 16 9 0,000 6,162E-03 0,01957622 ! protein complex disassembly GO:0043241 17 9 0,000 6,162E-03 0,01954922 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 6,162E-03 0,01952229 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 6,162E-03 0,01949544 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 6,162E-03 0,01946866 ! lung alveolus development GO:0048286 17 9 0,000 6,162E-03 0,01944195 ! ciliary or flagellar motility GO:0001539 10 9 0,000 6,162E-03 0,01941532 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 6,162E-03 0,01938876 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 6,162E-03 0,01936227 ! regulation of exit from mitosis GO:0007096 12 9 0,000 6,162E-03 0,01933586 ! ventral spinal cord development GO:0021517 11 9 0,000 6,162E-03 0,01930952 ! protein targeting to ER GO:0045047 19 9 0,000 6,162E-03 0,01928324 ! T cell selection GO:0045058 18 9 0,000 6,162E-03 0,01925704 ! endoderm development GO:0007492 12 9 0,000 6,162E-03 0,01923091 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 6,162E-03 0,01920486 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 6,162E-03 0,01917887 ! arginine catabolic process GO:0006527 10 9 0,000 6,162E-03 0,01915295 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 6,162E-03 0,0191271 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 6,162E-03 0,01910133 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 6,162E-03 0,01907562 ! phosphagen metabolic process GO:0006599 12 9 0,000 6,162E-03 0,01904998 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 6,162E-03 0,01902441 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 6,162E-03 0,01899891 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 6,162E-03 0,01897347 ! regulation of stress fiber formation GO:0051492 20 9 0,000 6,162E-03 0,01894811 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 6,162E-03 0,01892281 ! mannose metabolic process GO:0006013 9 9 0,000 6,162E-03 0,01889758 ! substrate-bound cell migration GO:0006929 10 9 0,000 6,162E-03 0,01887242 ! receptor clustering GO:0043113 15 9 0,000 6,162E-03 0,01884732 ! epithelial cell development GO:0002064 10 9 0,000 6,162E-03 0,01882229 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 6,162E-03 0,01879733 ! retinoic acid metabolic process GO:0042573 11 9 0,000 6,162E-03 0,01877243 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 6,162E-03 0,0187476 ! positive regulation of translational initiation GO:0045948 10 9 0,000 6,162E-03 0,01872283 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 6,162E-03 0,01869813 ! motor axon guidance GO:0008045 14 9 0,000 6,162E-03 0,0186735 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 6,162E-03 0,01864893 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 6,162E-03 0,01862442 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 6,162E-03 0,01859998 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 6,162E-03 0,0185756 ! blastoderm segmentation GO:0007350 11 9 0,000 6,162E-03 0,01855129 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 6,162E-03 0,01852704 ! DNA ligation GO:0006266 14 9 0,000 6,162E-03 0,01850285 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 6,162E-03 0,01847873 ! response to amine stimulus GO:0014075 13 9 0,000 6,162E-03 0,01845467 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 6,162E-03 0,01843067 ! erythrocyte development GO:0048821 11 9 0,000 6,162E-03 0,01840673 ! renal water homeostasis GO:0003091 14 9 0,000 6,162E-03 0,01838286 ! postreplication repair GO:0006301 11 9 0,000 6,162E-03 0,01835905 ! mRNA cleavage GO:0006379 13 9 0,000 6,162E-03 0,0183353 ! hindbrain morphogenesis GO:0021575 12 9 0,000 6,162E-03 0,01831161 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 6,162E-03 0,01828798 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 6,162E-03 0,01826441 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 6,162E-03 0,01824091 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 6,162E-03 0,01821746 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 6,162E-03 0,01819407 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 6,162E-03 0,01817075 ! acid secretion GO:0046717 14 9 0,000 6,162E-03 0,01814748 ! musculoskeletal movement GO:0050881 11 9 0,000 6,162E-03 0,01812428 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 6,162E-03 0,01810113 ! methionine biosynthetic process GO:0009086 10 9 0,000 6,162E-03 0,01807804 ! purine base metabolic process GO:0006144 18 9 0,000 6,162E-03 0,01805501 ! oocyte differentiation GO:0009994 12 9 0,000 6,162E-03 0,01803204 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 6,162E-03 0,01800913 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 6,162E-03 0,01798627 ! spleen development GO:0048536 15 9 0,000 6,162E-03 0,01796348 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 6,162E-03 0,01794074 ! anterior/posterior axis specification GO:0009948 11 9 0,000 6,162E-03 0,01791806 ! regulation of RNA splicing GO:0043484 14 9 0,000 6,162E-03 0,01789543 ! detection of calcium ion GO:0005513 13 9 0,000 6,162E-03 0,01787287 ! blastocyst formation GO:0001825 12 9 0,000 6,162E-03 0,01785036 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 6,162E-03 0,0178279 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 6,162E-03 0,01780551 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 6,162E-03 0,01778317 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 6,162E-03 0,01776088 ! regulation of amino acid transport GO:0051955 11 9 0,000 6,162E-03 0,01773865 ! positive regulation of amine transport GO:0051954 15 9 0,000 6,162E-03 0,01771648 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 6,162E-03 0,01769436 ! prepulse inhibition GO:0060134 14 9 0,000 6,162E-03 0,0176723 ! embryonic placenta development GO:0001892 12 9 0,000 6,162E-03 0,01765029 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 6,162E-03 0,01762834 ! insulin secretion GO:0030073 17 9 0,000 6,162E-03 0,01760644 ! sequestering of metal ion GO:0051238 11 9 0,000 6,162E-03 0,0175846 ! response to nicotine GO:0035094 16 9 0,000 6,162E-03 0,01756281 ! establishment of cell polarity GO:0030010 12 9 0,000 6,162E-03 0,01754107 ! nucleus localization GO:0051647 15 9 0,000 6,162E-03 0,01751939 ! regulation of synapse organization GO:0050807 12 9 0,000 6,162E-03 0,01749776 ! localization within membrane GO:0051668 15 9 0,000 6,162E-03 0,01747618 ! negative regulation of muscle development GO:0048635 12 10 0,000 6,845E-03 0,01938797 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 6,845E-03 0,01936412 ! neuron fate specification GO:0048665 11 10 0,000 6,845E-03 0,01934033 ! negative regulation of blood pressure GO:0045776 22 10 0,000 6,845E-03 0,0193166 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 6,845E-03 0,01929293 ! thyroid gland development GO:0030878 19 10 0,000 6,845E-03 0,01926932 ! regulation of B cell proliferation GO:0030888 15 10 0,000 6,845E-03 0,01924576 ! regulation of phosphatase activity GO:0010921 21 10 0,000 6,845E-03 0,01922226 ! synapsis GO:0007129 13 10 0,000 6,845E-03 0,01919882 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 6,845E-03 0,01917543 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 6,845E-03 0,01915211 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 6,845E-03 0,01912883 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 6,845E-03 0,01910562 ! sulfate transport GO:0008272 12 10 0,000 6,845E-03 0,01908246 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 6,845E-03 0,01905936 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 6,845E-03 0,01903631 ! androgen metabolic process GO:0008209 13 10 0,000 6,845E-03 0,01901332 ! phospholipid efflux GO:0033700 16 10 0,000 6,845E-03 0,01899039 ! hippocampus development GO:0021766 19 10 0,000 6,845E-03 0,01896751 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 6,845E-03 0,01894468 ! blood vessel remodeling GO:0001974 21 10 0,000 6,845E-03 0,01892191 ! positive regulation of heart contraction GO:0045823 14 10 0,000 6,845E-03 0,0188992 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 6,845E-03 0,01887654 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 6,845E-03 0,01885393 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 6,845E-03 0,01883138 ! pathogenesis GO:0009405 13 10 0,000 6,845E-03 0,01880888 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 6,845E-03 0,01878643 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 6,845E-03 0,01876404 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 6,845E-03 0,0187417 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 6,845E-03 0,01871942 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 6,845E-03 0,01869719 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 6,845E-03 0,01867501 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 6,845E-03 0,01865288 ! melanocyte differentiation GO:0030318 15 10 0,000 6,845E-03 0,01863081 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 6,845E-03 0,01860878 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 6,845E-03 0,01858681 ! reverse cholesterol transport GO:0043691 16 10 0,000 6,845E-03 0,01856489 ! response to X-ray GO:0010165 16 10 0,000 6,845E-03 0,01854303 ! B cell proliferation GO:0042100 14 10 0,000 6,845E-03 0,01852121 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 6,845E-03 0,01849945 ! regulation of sodium ion transport GO:0002028 15 10 0,000 6,845E-03 0,01847774 ! forebrain cell migration GO:0021885 17 10 0,000 6,845E-03 0,01845607 ! lipid digestion GO:0044241 15 10 0,000 6,845E-03 0,01843446 ! phagocytosis, engulfment GO:0006911 20 10 0,000 6,845E-03 0,0184129 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 6,845E-03 0,01839139 ! UV protection GO:0009650 14 10 0,000 6,845E-03 0,01836993 ! entry into host cell GO:0030260 20 10 0,000 6,845E-03 0,01834852 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 6,845E-03 0,01832716 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 6,845E-03 0,01830585 ! negative regulation of ossification GO:0030279 19 10 0,000 6,845E-03 0,01828459 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 6,845E-03 0,01826338 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 6,845E-03 0,01824221 ! regulation of bone resorption GO:0045124 24 10 0,000 6,845E-03 0,0182211 ! alpha-beta T cell activation GO:0046631 16 10 0,000 6,845E-03 0,01820004 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 6,845E-03 0,01817902 ! regulation of organ growth GO:0046620 11 10 0,000 6,845E-03 0,01815805 ! response to dsRNA GO:0043331 18 10 0,000 6,845E-03 0,01813713 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 6,845E-03 0,01811626 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 6,845E-03 0,01809544 ! embryonic axis specification GO:0000578 12 10 0,000 6,845E-03 0,01807466 ! regulation of B cell differentiation GO:0045577 16 10 0,000 6,845E-03 0,01805393 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 6,845E-03 0,01803325 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 6,845E-03 0,01801262 ! cranial nerve development GO:0021545 12 10 0,000 6,845E-03 0,01799203 ! fucose catabolic process GO:0019317 16 10 0,000 6,845E-03 0,0179715 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 6,845E-03 0,017951 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 6,845E-03 0,01793056 ! protein sumoylation GO:0016925 12 10 0,000 6,845E-03 0,01791016 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 6,845E-03 0,01788981 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 6,845E-03 0,0178695 ! zymogen activation GO:0031638 14 10 0,000 6,845E-03 0,01784924 ! salivary gland development GO:0007431 22 10 0,000 6,845E-03 0,01782903 ! negative regulation of neurological system process GO:0031645 19 10 0,000 6,845E-03 0,01780886 ! glutathione biosynthetic process GO:0006750 11 10 0,000 6,845E-03 0,01778873 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 6,845E-03 0,01776866 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 6,845E-03 0,01774862 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 6,845E-03 0,01772864 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 6,845E-03 0,0177087 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 6,845E-03 0,0176888 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 6,845E-03 0,01766895 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 6,845E-03 0,01764914 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 6,845E-03 0,01762937 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 6,845E-03 0,01760965 ! detection of bacterium GO:0016045 10 10 0,000 6,845E-03 0,01758998 ! embryonic gut development GO:0048566 11 10 0,000 6,845E-03 0,01757035 ! activation of innate immune response GO:0002218 10 10 0,000 6,845E-03 0,01755076 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 6,845E-03 0,01753121 ! cardiac cell differentiation GO:0035051 16 10 0,000 6,845E-03 0,01751171 ! developmental induction GO:0031128 13 10 0,000 6,845E-03 0,01749226 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 6,845E-03 0,01747284 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 6,845E-03 0,01745347 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 6,845E-03 0,01743414 ! negative regulation of immune effector process GO:0002698 16 10 0,000 6,845E-03 0,01741486 ! rRNA transcription GO:0009303 17 11 0,000 7,527E-03 0,01912916 ! respiratory burst GO:0045730 14 11 0,000 7,527E-03 0,01910804 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 7,527E-03 0,01908698 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 7,527E-03 0,01906596 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 7,527E-03 0,01904498 ! virus-host interaction GO:0019048 17 11 0,000 7,527E-03 0,01902405 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 7,527E-03 0,01900317 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 7,527E-03 0,01898233 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 7,527E-03 0,01896154 ! Golgi vesicle budding GO:0048194 17 11 0,000 7,527E-03 0,0189408 ! RNA polyadenylation GO:0043631 19 11 0,000 7,527E-03 0,0189201 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 7,527E-03 0,01889944 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 7,527E-03 0,01887883 ! mating GO:0007618 14 11 0,000 7,527E-03 0,01885827 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 7,527E-03 0,01883775 ! T cell proliferation GO:0042098 20 11 0,000 7,527E-03 0,01881727 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 7,527E-03 0,01879684 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 7,527E-03 0,01877645 ! bone resorption GO:0045453 16 11 0,000 7,527E-03 0,01875611 ! regulated secretory pathway GO:0045055 14 11 0,000 7,527E-03 0,01873581 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 7,527E-03 0,01871555 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 7,527E-03 0,01869534 ! regulation of mRNA processing GO:0050684 18 11 0,000 7,527E-03 0,01867518 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 7,527E-03 0,01865505 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 7,527E-03 0,01863497 ! syncytium formation GO:0006949 15 11 0,000 7,527E-03 0,01861493 ! plasma membrane organization GO:0007009 18 11 0,000 7,527E-03 0,01859494 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 7,527E-03 0,01857499 ! focal adhesion formation GO:0048041 24 11 0,000 7,527E-03 0,01855508 ! mitotic spindle organization GO:0007052 15 11 0,000 7,527E-03 0,01853521 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 7,527E-03 0,01851539 ! regulation of intracellular pH GO:0051453 17 11 0,000 7,527E-03 0,01849561 ! membrane protein proteolysis GO:0033619 18 11 0,000 7,527E-03 0,01847587 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 7,527E-03 0,01845617 ! adult heart development GO:0007512 11 11 0,000 7,527E-03 0,01843652 ! chondrocyte differentiation GO:0002062 17 11 0,000 7,527E-03 0,0184169 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 7,527E-03 0,01839733 ! temperature homeostasis GO:0001659 16 11 0,000 7,527E-03 0,0183778 ! L-glutamate transport GO:0015813 16 11 0,000 7,527E-03 0,01835831 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 7,527E-03 0,01833886 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 7,527E-03 0,01831946 ! protein targeting to peroxisome GO:0006625 20 11 0,000 7,527E-03 0,01830009 ! stem cell development GO:0048864 29 11 0,000 7,527E-03 0,01828077 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 7,527E-03 0,01826149 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 7,527E-03 0,01824224 ! regulation of phagocytosis GO:0050764 14 11 0,000 7,527E-03 0,01822304 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 7,527E-03 0,01820388 ! vasoconstriction GO:0042310 15 11 0,000 7,527E-03 0,01818476 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 7,527E-03 0,01816567 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 7,527E-03 0,01814663 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 7,527E-03 0,01812763 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 7,527E-03 0,01810867 ! ribosome assembly GO:0042255 13 11 0,000 7,527E-03 0,01808975 ! nitric oxide metabolic process GO:0046209 14 11 0,000 7,527E-03 0,01807086 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 7,527E-03 0,01805202 ! chromatin silencing GO:0006342 19 11 0,000 7,527E-03 0,01803322 ! nucleosome positioning GO:0016584 13 11 0,000 7,527E-03 0,01801445 ! T cell homeostasis GO:0043029 20 11 0,000 7,527E-03 0,01799573 ! regulation of isotype switching GO:0045191 19 11 0,000 7,527E-03 0,01797704 ! regulation of leukocyte migration GO:0002685 24 11 0,000 7,527E-03 0,01795839 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 7,527E-03 0,01793978 ! protein-chromophore linkage GO:0018298 13 11 0,000 7,527E-03 0,01792121 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 7,527E-03 0,01790268 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 7,527E-03 0,01788418 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 7,527E-03 0,01786573 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 7,527E-03 0,01784731 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 7,527E-03 0,01782893 ! male genitalia development GO:0030539 13 11 0,000 7,527E-03 0,01781058 ! cholesterol efflux GO:0033344 19 11 0,000 7,527E-03 0,01779228 ! digestive tract morphogenesis GO:0048546 15 11 0,000 7,527E-03 0,01777401 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 7,527E-03 0,01775578 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 7,527E-03 0,01773759 ! negative regulation of glucose import GO:0046325 14 11 0,000 7,527E-03 0,01771944 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 7,527E-03 0,01770132 ! regulation of organic acid transport GO:0032890 17 11 0,000 7,527E-03 0,01768324 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 7,527E-03 0,01766519 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 7,527E-03 0,01764718 ! mRNA 3'-end processing GO:0031124 19 11 0,000 7,527E-03 0,01762921 ! lysogeny GO:0030069 18 11 0,000 7,527E-03 0,01761128 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 7,527E-03 0,01759338 ! acrosome reaction GO:0007340 13 11 0,000 7,527E-03 0,01757552 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 7,527E-03 0,0175577 ! lactation GO:0007595 20 12 0,000 8,209E-03 0,01912843 ! reproductive cellular process GO:0048610 14 12 0,000 8,209E-03 0,01910907 ! tRNA modification GO:0006400 14 12 0,000 8,209E-03 0,01908975 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 8,209E-03 0,01907046 ! positive regulation of blood pressure GO:0045777 16 12 0,000 8,209E-03 0,01905122 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 8,209E-03 0,01903201 ! 'de novo' protein folding GO:0006458 18 12 0,000 8,209E-03 0,01901285 ! dicarboxylic acid transport GO:0006835 22 12 0,000 8,209E-03 0,01899372 ! non-recombinational repair GO:0000726 19 12 0,000 8,209E-03 0,01897463 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 8,209E-03 0,01895558 ! peroxisomal transport GO:0043574 21 12 0,000 8,209E-03 0,01893657 ! cartilage condensation GO:0001502 18 12 0,000 8,209E-03 0,01891759 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 8,209E-03 0,01889866 ! cytokine biosynthetic process GO:0042089 16 12 0,000 8,209E-03 0,01887976 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 8,209E-03 0,0188609 ! heart looping GO:0001947 15 12 0,000 8,209E-03 0,01884207 ! palate development GO:0060021 15 12 0,000 8,209E-03 0,01882329 ! positive regulation of cell growth GO:0030307 16 12 0,000 8,209E-03 0,01880454 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 8,209E-03 0,01878583 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 8,209E-03 0,01876716 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 8,209E-03 0,01874852 ! arginine metabolic process GO:0006525 13 12 0,000 8,209E-03 0,01872992 ! glycoprotein catabolic process GO:0006516 19 12 0,000 8,209E-03 0,01871136 ! methionine metabolic process GO:0006555 13 12 0,000 8,209E-03 0,01869283 ! tyrosine metabolic process GO:0006570 14 12 0,000 8,209E-03 0,01867434 ! Golgi organization GO:0007030 18 12 0,000 8,209E-03 0,01865589 ! cell-cell junction assembly GO:0007043 18 12 0,000 8,209E-03 0,01863747 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 8,209E-03 0,01861909 ! monoamine transport GO:0015844 13 12 0,000 8,209E-03 0,01860075 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 8,209E-03 0,01858244 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 8,209E-03 0,01856417 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 8,209E-03 0,01854593 ! L-amino acid transport GO:0015807 20 12 0,000 8,209E-03 0,01852773 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 8,209E-03 0,01850957 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 8,209E-03 0,01849144 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 8,209E-03 0,01847334 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 8,209E-03 0,01845529 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 8,209E-03 0,01843726 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 8,209E-03 0,01841928 ! cerebellum development GO:0021549 13 12 0,000 8,209E-03 0,01840132 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 8,209E-03 0,01838341 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 8,209E-03 0,01836552 ! histone acetylation GO:0016573 23 12 0,000 8,209E-03 0,01834768 ! histone methylation GO:0016571 15 12 0,000 8,209E-03 0,01832986 ! autonomic nervous system development GO:0048483 23 12 0,000 8,209E-03 0,01831208 ! gland morphogenesis GO:0022612 23 12 0,000 8,209E-03 0,01829434 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 8,209E-03 0,01827663 ! peptidyl-lysine modification GO:0018205 18 12 0,000 8,209E-03 0,01825895 ! negative regulation of protein secretion GO:0050709 20 12 0,000 8,209E-03 0,01824131 ! response to gamma radiation GO:0010332 20 12 0,000 8,209E-03 0,0182237 ! intestinal absorption GO:0050892 19 12 0,000 8,209E-03 0,01820613 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 8,209E-03 0,01818859 ! cAMP biosynthetic process GO:0006171 20 12 0,000 8,209E-03 0,01817109 ! regulation of mRNA stability GO:0043488 27 12 0,000 8,209E-03 0,01815361 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 8,209E-03 0,01813618 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 8,209E-03 0,01811877 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 8,209E-03 0,0181014 ! RNA 3'-end processing GO:0031123 20 12 0,000 8,209E-03 0,01808406 ! microspike assembly GO:0030035 23 12 0,000 8,209E-03 0,01806675 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 8,209E-03 0,01804948 ! response to cold GO:0009409 14 12 0,000 8,209E-03 0,01803224 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 8,89E-03 0,01951015 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 8,89E-03 0,01949155 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 8,89E-03 0,01947299 ! cGMP metabolic process GO:0046068 16 13 0,000 8,89E-03 0,01945446 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 8,89E-03 0,01943597 ! water transport GO:0006833 17 13 0,000 8,89E-03 0,01941751 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 8,89E-03 0,01939909 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 8,89E-03 0,0193807 ! lipid localization GO:0010876 24 13 0,000 8,89E-03 0,01936235 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 8,89E-03 0,01934403 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 8,89E-03 0,01932575 ! organelle fusion GO:0048284 28 13 0,000 8,89E-03 0,0193075 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 8,89E-03 0,01928928 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 8,89E-03 0,0192711 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 8,89E-03 0,01925296 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 8,89E-03 0,01923485 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 8,89E-03 0,01921677 ! response to hexose stimulus GO:0009746 19 13 0,000 8,89E-03 0,01919872 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! glutamate metabolic process GO:0006536 18 13 0,000 8,89E-03 0,01918071 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 8,89E-03 0,01916274 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 8,89E-03 0,01914479 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 8,89E-03 0,01912689 ! NAD metabolic process GO:0019674 21 13 0,000 8,89E-03 0,01910901 ! exocrine system development GO:0035272 27 13 0,000 8,89E-03 0,01909117 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 8,89E-03 0,01907336 ! bone mineralization GO:0030282 15 13 0,000 8,89E-03 0,01905558 ! regulation of exocytosis GO:0017157 17 13 0,000 8,89E-03 0,01903784 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 8,89E-03 0,01902013 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 8,89E-03 0,01900245 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 8,89E-03 0,01898481 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 8,89E-03 0,0189672 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 8,89E-03 0,01894962 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 8,89E-03 0,01893208 ! genitalia development GO:0048806 15 13 0,000 8,89E-03 0,01891456 ! regulation of cellular pH GO:0030641 20 13 0,000 8,89E-03 0,01889708 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 8,89E-03 0,01887963 ! cellular pigmentation GO:0033059 24 13 0,000 8,89E-03 0,01886221 ! tissue regeneration GO:0042246 21 13 0,000 8,89E-03 0,01884483 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 8,89E-03 0,01882748 ! cofactor transport GO:0051181 19 13 0,000 8,89E-03 0,01881016 ! NADP metabolic process GO:0006739 18 13 0,000 8,89E-03 0,01879287 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 8,89E-03 0,01877561 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 8,89E-03 0,01875839 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 8,89E-03 0,01874119 ! gas transport GO:0015669 18 13 0,000 8,89E-03 0,01872403 ! regulation of RNA stability GO:0043487 28 13 0,000 8,89E-03 0,0187069 ! heme biosynthetic process GO:0006783 20 13 0,000 8,89E-03 0,0186898 ! regulation of axon extension GO:0030516 23 13 0,000 8,89E-03 0,01867273 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 8,89E-03 0,01865569 ! lymphocyte homeostasis GO:0002260 24 13 0,000 8,89E-03 0,01863869 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 8,89E-03 0,01862171 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 8,89E-03 0,01860477 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 8,89E-03 0,01858786 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 8,89E-03 0,01857097 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 9,571E-03 0,01997508 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 9,571E-03 0,01995697 ! superoxide anion generation GO:0042554 18 14 0,000 9,571E-03 0,01993889 ! neuron maturation GO:0042551 21 14 0,000 9,571E-03 0,01992085 ! regulation of S phase GO:0033261 18 14 0,000 9,571E-03 0,01990284 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 9,571E-03 0,01988486 ! myotube differentiation GO:0014902 21 14 0,000 9,571E-03 0,01986691 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 9,571E-03 0,019849 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 9,571E-03 0,01983111 ! heterophilic cell adhesion GO:0007157 29 14 0,000 9,571E-03 0,01981326 ! inositol metabolic process GO:0006020 20 14 0,000 9,571E-03 0,01979545 ! aminoglycan catabolic process GO:0006026 18 14 0,000 9,571E-03 0,01977766 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 9,571E-03 0,01975991 ! retina development in camera-type eye GO:0060041 18 14 0,000 9,571E-03 0,01974219 ! cardiac muscle contraction GO:0060048 23 14 0,000 9,571E-03 0,0197245 ! gene silencing by RNA GO:0031047 20 14 0,000 9,571E-03 0,01970684 ! response to cAMP GO:0051591 19 14 0,000 9,571E-03 0,01968921 ! limbic system development GO:0021761 25 14 0,000 9,571E-03 0,01967162 ! startle response GO:0001964 21 14 0,000 9,571E-03 0,01965405 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 9,571E-03 0,01963652 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 9,571E-03 0,01961902 ! activation of MAPKK activity GO:0000186 21 14 0,000 9,571E-03 0,01960155 ! regulation of defense response to virus GO:0050688 24 14 0,000 9,571E-03 0,01958411 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 9,571E-03 0,0195667 ! epidermis morphogenesis GO:0048730 29 14 0,000 9,571E-03 0,01954932 ! glycine metabolic process GO:0006544 22 14 0,000 9,571E-03 0,01953198 ! pituitary gland development GO:0021983 23 14 0,000 9,571E-03 0,01951466 ! cellular response to starvation GO:0009267 21 14 0,000 9,571E-03 0,01949738 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 9,571E-03 0,01948012 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 9,571E-03 0,0194629 ! regulation of heart rate GO:0002027 23 14 0,000 9,571E-03 0,0194457 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 9,571E-03 0,01942854 ! negative regulation of caspase activity GO:0043154 20 14 0,000 9,571E-03 0,01941141 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 9,571E-03 0,01939431 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 9,571E-03 0,01937723 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 9,571E-03 0,01936019 ! G1/S transition checkpoint GO:0031575 33 14 0,000 9,571E-03 0,01934318 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 9,571E-03 0,0193262 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 9,571E-03 0,01930924 ! axon cargo transport GO:0008088 27 14 0,000 9,571E-03 0,01929232 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 9,571E-03 0,01927543 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 9,571E-03 0,01925856 ! DNA unwinding during replication GO:0006268 21 14 0,000 9,571E-03 0,01924173 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 9,571E-03 0,01922492 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 9,571E-03 0,01920815 ! mRNA splice site selection GO:0006376 26 14 0,000 9,571E-03 0,0191914 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 9,571E-03 0,01917468 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 9,571E-03 0,019158 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 9,571E-03 0,01914134 ! sphingolipid catabolic process GO:0030149 23 14 0,000 9,571E-03 0,01912471 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 9,571E-03 0,01910811 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 9,571E-03 0,01909153 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 9,571E-03 0,01907499 ! muscle maintenance GO:0046716 19 14 0,000 9,571E-03 0,01905847 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 9,571E-03 0,01904199 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 9,571E-03 0,01902553 ! regulation of ATPase activity GO:0043462 18 14 0,000 9,571E-03 0,0190091 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 9,571E-03 0,0189927 ! cell killing GO:0001906 20 14 0,000 9,571E-03 0,01897633 ! release of cytochrome c from mitochondria GO:0001836 23 14 0,000 9,571E-03 0,01895998 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 9,571E-03 0,01894366 ! cilium assembly GO:0042384 20 14 0,000 9,571E-03 0,01892738 ! peptide hormone secretion GO:0030072 23 14 0,000 9,571E-03 0,01891111 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,01025106 0,02023815 ! positive regulation of cell size GO:0045793 20 15 0,000 0,01025106 0,0202208 ! metencephalon development GO:0022037 19 15 0,000 0,01025106 0,02020347 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,01025106 0,02018617 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,01025106 0,0201689 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,01025106 0,02015166 ! skin development GO:0043588 25 15 0,000 0,01025106 0,02013446 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,01025106 0,02011728 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,01025106 0,02010013 ! lipid phosphorylation GO:0046834 23 15 0,000 0,01025106 0,020083 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,01025106 0,02006591 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,01025106 0,02004885 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,01025106 0,02003182 ! bile acid metabolic process GO:0008206 22 15 0,000 0,01025106 0,02001481 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,01025106 0,01999783 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,01025106 0,01998089 ! adult walking behavior GO:0007628 25 15 0,000 0,01025106 0,01996397 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,01025106 0,01994708 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,01025106 0,01993022 ! myoblast differentiation GO:0045445 27 15 0,000 0,01025106 0,01991338 ! centrosome cycle GO:0007098 16 15 0,000 0,01025106 0,01989658 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,01025106 0,0198798 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,01025106 0,01986306 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,01025106 0,01984634 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,01025106 0,01982964 ! cerebral cortex development GO:0021987 29 15 0,000 0,01025106 0,01981298 ! response to osmotic stress GO:0006970 22 15 0,000 0,01025106 0,01979635 ! vesicle coating GO:0006901 25 15 0,000 0,01025106 0,01977974 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,01025106 0,01976316 ! DNA integration GO:0015074 22 15 0,000 0,01025106 0,01974661 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,01025106 0,01973008 ! peptide secretion GO:0002790 27 15 0,000 0,01025106 0,01971358 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,01025106 0,01969712 ! regulation of vasodilation GO:0042312 24 15 0,000 0,01025106 0,01968067 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,01025106 0,01966426 ! neuron recognition GO:0008038 22 15 0,000 0,01025106 0,01964787 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,01025106 0,01963151 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,01025106 0,01961518 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,01025106 0,01959888 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,01025106 0,0195826 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,01025106 0,01956635 ! biomineral formation GO:0031214 18 15 0,000 0,01025106 0,01955012 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,01025106 0,01953392 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,01025106 0,01951775 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,01025106 0,01950161 ! dopamine metabolic process GO:0042417 30 15 0,000 0,01025106 0,01948549 ! organic cation transport GO:0015695 19 15 0,000 0,01025106 0,0194694 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,01025106 0,01945334 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,01025106 0,0194373 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,01025106 0,01942129 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,01025106 0,01940531 ! defense response to virus GO:0051607 27 15 0,000 0,01025106 0,01938935 ! peptide hormone processing GO:0016486 19 15 0,000 0,01025106 0,01937342 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,01025106 0,01935751 ! protein secretion GO:0009306 27 16 0,000 0,01093103 0,02062459 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,01093103 0,02060768 ! hormone secretion GO:0046879 25 16 0,000 0,01093103 0,0205908 ! bone remodeling GO:0046849 24 16 0,000 0,01093103 0,02057395 ! endothelial cell migration GO:0043542 22 16 0,000 0,01093103 0,02055713 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,01093103 0,02054034 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,01093103 0,02052357 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,01093103 0,02050683 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,01093103 0,02049012 ! glial cell development GO:0021782 24 16 0,000 0,01093103 0,02047343 ! patterning of blood vessels GO:0001569 24 16 0,000 0,01093103 0,02045677 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,01093103 0,02044014 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,01093103 0,02042354 ! protein polyubiquitination GO:0000209 26 16 0,000 0,01093103 0,02040696 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,01093103 0,02039041 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,01093103 0,02037388 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,01093103 0,02035739 ! fructose metabolic process GO:0006000 20 16 0,000 0,01093103 0,02034092 ! regulation of protein binding GO:0043393 27 16 0,000 0,01093103 0,02032447 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,01093103 0,02030805 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,01093103 0,02029166 ! protein export from nucleus GO:0006611 24 16 0,000 0,01093103 0,0202753 ! negative regulation of immune response GO:0050777 28 16 0,000 0,01093103 0,02025896 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,01093103 0,02024265 ! DNA replication initiation GO:0006270 25 16 0,000 0,01093103 0,02022637 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,01093103 0,02021011 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,01093103 0,02019387 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,01093103 0,02017767 ! diencephalon development GO:0021536 25 16 0,000 0,01093103 0,02016149 ! oogenesis GO:0048477 23 16 0,000 0,01093103 0,02014533 ! neural crest cell migration GO:0001755 24 16 0,000 0,01093103 0,0201292 ! G1 phase GO:0051318 27 16 0,000 0,01093103 0,0201131 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,01093103 0,02009702 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,01093103 0,02008097 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,01093103 0,02006494 ! steroid catabolic process GO:0006706 22 16 0,000 0,01093103 0,02004894 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,01093103 0,02003297 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,01093103 0,02001702 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,01093103 0,02000109 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,01093103 0,01998519 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,01093103 0,01996932 ! sperm-egg recognition GO:0035036 16 16 0,000 0,01093103 0,01995347 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,01093103 0,01993765 ! nerve development GO:0021675 18 16 0,000 0,01093103 0,01992185 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,01093103 0,01990607 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,01093103 0,01989033 ! negative regulation of translation GO:0017148 22 16 0,000 0,01093103 0,0198746 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,01161057 0,02109345 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,01161057 0,0210768 ! negative regulation of defense response GO:0031348 19 17 0,000 0,01161057 0,02106018 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,01161057 0,02104359 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,01161057 0,02102702 ! glycerol metabolic process GO:0006071 20 17 0,000 0,01161057 0,02101047 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,01161057 0,02099396 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,01161057 0,02097746 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,01161057 0,020961 ! signal complex assembly GO:0007172 29 17 0,000 0,01161057 0,02094456 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,01161057 0,02092814 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,01161057 0,02091176 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,01161057 0,02089539 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,01161057 0,02087906 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,01161057 0,02086274 ! memory GO:0007613 25 17 0,000 0,01161057 0,02084646 ! keratinization GO:0031424 17 17 0,000 0,01161057 0,0208302 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,01161057 0,02081396 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,01161057 0,02079775 ! retinoid metabolic process GO:0001523 22 17 0,000 0,01161057 0,02078157 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,01161057 0,02076541 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,01161057 0,02074927 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,01161057 0,02073316 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,01161057 0,02071708 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,01161057 0,02070102 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,01161057 0,02068498 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 0,000 0,01161057 0,02066897 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,01161057 0,02065299 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,01161057 0,02063703 ! membrane budding GO:0006900 29 17 0,000 0,01161057 0,02062109 ! heme metabolic process GO:0042168 27 17 0,000 0,01161057 0,02060518 ! actin filament bundle formation GO:0051017 26 17 0,000 0,01161057 0,02058929 ! neuromuscular junction development GO:0007528 23 17 0,000 0,01161057 0,02057343 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,01161057 0,02055759 ! body fluid secretion GO:0007589 27 17 0,000 0,01161057 0,02054178 ! stem cell differentiation GO:0048863 36 17 0,000 0,01161057 0,02052599 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,01161057 0,02051022 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,01161057 0,02049448 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,01161057 0,02047877 ! sensory perception of pain GO:0019233 23 17 0,000 0,01161057 0,02046307 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,01161057 0,02044741 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,01161057 0,02043176 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,01161057 0,02041614 ! synaptogenesis GO:0007416 24 17 0,000 0,01161057 0,02040054 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,01161057 0,02038497 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,01161057 0,02036942 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,01161057 0,0203539 ! cell-cell junction organization GO:0045216 25 17 0,000 0,01161057 0,02033839 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,01161057 0,02032292 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,01161057 0,02030746 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,01161057 0,02029203 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,01161057 0,02027662 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,01161057 0,02026124 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,01161057 0,02024588 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,01228968 0,02141384 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,01228968 0,02139763 ! positive regulation of translation GO:0045727 28 18 0,000 0,01228968 0,02138144 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,01228968 0,02136528 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,01228968 0,02134914 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,01228968 0,02133303 ! cAMP metabolic process GO:0046058 33 18 0,000 0,01228968 0,02131694 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,01228968 0,02130088 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,01228968 0,02128484 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,01228968 0,02126882 ! axis specification GO:0009798 26 18 0,000 0,01228968 0,02125283 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,01228968 0,02123686 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,01228968 0,02122092 ! pancreas development GO:0031016 26 18 0,000 0,01228968 0,021205 ! apoptotic mitochondrial changes GO:0008637 29 18 0,000 0,01228968 0,02118911 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,01228968 0,02117323 ! glutamine metabolic process GO:0006541 23 18 0,000 0,01228968 0,02115739 ! response to retinoic acid GO:0032526 25 18 0,000 0,01228968 0,02114156 ! pigmentation during development GO:0048066 31 18 0,000 0,01228968 0,02112576 ! central nervous system neuron development GO:0021954 30 18 0,000 0,01228968 0,02110998 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,01228968 0,02109423 ! fucose metabolic process GO:0006004 26 18 0,000 0,01228968 0,0210785 ! response to fungus GO:0009620 19 18 0,000 0,01228968 0,02106279 ! peptide cross-linking GO:0018149 31 18 0,000 0,01228968 0,02104711 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,01228968 0,02103145 ! heart process GO:0003015 27 18 0,000 0,01228968 0,02101581 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,01228968 0,0210002 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,01228968 0,02098461 ! visual learning GO:0008542 35 18 0,000 0,01228968 0,02096904 ! somitogenesis GO:0001756 24 18 0,000 0,01228968 0,0209535 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,01228968 0,02093798 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,01228968 0,02092248 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,01228968 0,020907 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,01228968 0,02089155 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,01228968 0,02087612 ! vitamin transport GO:0051180 24 18 0,000 0,01228968 0,02086071 ! hormone transport GO:0009914 27 18 0,000 0,01228968 0,02084533 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,01228968 0,02082997 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,01228968 0,02081463 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,01228968 0,02079931 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,01228968 0,02078402 ! cell-cell recognition GO:0009988 20 18 0,000 0,01228968 0,02076875 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,01228968 0,0207535 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,01228968 0,02073827 ! regulation of glucose import GO:0046324 21 18 0,000 0,01228968 0,02072307 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,01228968 0,02070789 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,01228968 0,02069273 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,01228968 0,02067759 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,01228968 0,02066248 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,01296836 0,02178761 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,01296836 0,02177171 ! positive regulation of fibroblast proliferation GO:0048146 27 19 0,000 0,01296836 0,02175583 ! positive regulation of ossification GO:0045778 30 19 0,000 0,01296836 0,02173997 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,01296836 0,02172414 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,01296836 0,02170832 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,01296836 0,02169254 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,01296836 0,02167677 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,01296836 0,02166103 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,01296836 0,02164531 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,01296836 0,02162961 ! regeneration GO:0031099 32 19 0,000 0,01296836 0,02161394 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,01296836 0,02159829 ! response to alkaloid GO:0043279 32 19 0,000 0,01296836 0,02158266 ! sensory perception of taste GO:0050909 23 19 0,000 0,01296836 0,02156706 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,01296836 0,02155147 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 0,000 0,01296836 0,02153591 ! smooth muscle contraction GO:0006939 36 19 0,000 0,01296836 0,02152037 ! peroxisome organization GO:0007031 29 19 0,000 0,01296836 0,02150486 ! digestive system process GO:0022600 30 19 0,000 0,01296836 0,02148936 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,01296836 0,02147389 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,01296836 0,02145844 ! response to vitamin A GO:0033189 26 19 0,000 0,01296836 0,02144302 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,01296836 0,02142761 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,01296836 0,02141223 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,01296836 0,02139687 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,01296836 0,02138153 ! response to starvation GO:0042594 30 19 0,000 0,01296836 0,02136622 ! sex determination GO:0007530 29 19 0,000 0,01296836 0,02135092 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,01296836 0,02133565 ! plasma membrane fusion GO:0045026 23 19 0,000 0,01296836 0,0213204 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,01296836 0,02130517 ! cytolysis GO:0019835 20 19 0,000 0,01296836 0,02128996 ! renal system process GO:0003014 35 19 0,000 0,01296836 0,02127478 ! vasodilation GO:0042311 33 19 0,000 0,01296836 0,02125961 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,01296836 0,02124447 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,01296836 0,02122935 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,01296836 0,02121425 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,01296836 0,02119917 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,01296836 0,02118412 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,01296836 0,02116908 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,01296836 0,02115407 ! sarcomere organization GO:0045214 23 19 0,000 0,01296836 0,02113908 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,01296836 0,02112411 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,01296836 0,02110916 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,01296836 0,02109423 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,01296836 0,02107932 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,01296836 0,02106443 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,01296836 0,02104957 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,01296836 0,02103472 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,01296836 0,0210199 ! protein stabilization GO:0050821 26 19 0,000 0,01296836 0,0210051 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,01364662 0,02208813 ! iron ion transport GO:0006826 37 20 0,000 0,01364662 0,02207259 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,01364662 0,02205708 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,01364662 0,02204159 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,01364662 0,02202612 ! response to vitamin GO:0033273 29 20 0,000 0,01364662 0,02201068 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,01364662 0,02199525 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,01364662 0,02197985 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,01364662 0,02196447 ! spinal cord development GO:0021510 31 20 0,000 0,01364662 0,02194911 ! response to ethanol GO:0045471 37 20 0,000 0,01364662 0,02193377 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,01364662 0,02191845 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 0,000 0,01364662 0,02190316 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,01364662 0,02188788 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,01364662 0,02187263 ! chromosome condensation GO:0030261 31 20 0,000 0,01364662 0,0218574 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,01364662 0,02184219 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,01364662 0,021827 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,01364662 0,02181183 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,01364662 0,02179668 ! pallium development GO:0021543 38 20 0,000 0,01364662 0,02178156 ! DNA modification GO:0006304 28 20 0,000 0,01364662 0,02176645 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,01364662 0,02175137 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,01364662 0,02173631 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,01364662 0,02172126 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,01364662 0,02170624 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,01364662 0,02169124 ! positive regulation of B cell activation GO:0050871 31 20 0,000 0,01364662 0,02167626 ! collagen catabolic process GO:0030574 25 20 0,000 0,01364662 0,0216613 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,01364662 0,02164636 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,01364662 0,02163144 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,01364662 0,02161655 ! alditol metabolic process GO:0019400 24 20 0,000 0,01364662 0,02160167 ! actin filament-based movement GO:0030048 34 20 0,000 0,01364662 0,02158681 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,01432445 0,02264346 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,01432445 0,02262791 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,01432445 0,02261238 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,01432445 0,02259687 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,01432445 0,02258138 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,01432445 0,02256591 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,01432445 0,02255047 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,01432445 0,02253504 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,01432445 0,02251964 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,01432445 0,02250426 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,01432445 0,0224889 ! protein amino acid acylation GO:0043543 37 21 0,000 0,01432445 0,02247356 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,01432445 0,02245824 ! vesicle docking GO:0048278 27 21 0,000 0,01432445 0,02244294 ! phototransduction GO:0007602 25 21 0,000 0,01432445 0,02242766 ! dendrite development GO:0016358 35 21 0,000 0,01432445 0,0224124 ! visual behavior GO:0007632 39 21 0,000 0,01432445 0,02239717 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,01432445 0,02238195 ! ovarian follicle development GO:0001541 30 21 0,000 0,01432445 0,02236676 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,01432445 0,02235158 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,01432445 0,02233643 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,01432445 0,0223213 ! cell aging GO:0007569 32 21 0,000 0,01432445 0,02230618 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,01432445 0,02229109 ! response to endoplasmic reticulum stress GO:0034976 25 21 0,000 0,01432445 0,02227602 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,01432445 0,02226097 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,01432445 0,02224594 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,01432445 0,02223093 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,01432445 0,02221594 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,01432445 0,02220096 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,01432445 0,02218601 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,01432445 0,02217108 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,01432445 0,02215617 ! fatty acid transport GO:0015908 30 21 0,000 0,01432445 0,02214128 ! immunoglobulin production GO:0002377 33 21 0,000 0,01432445 0,02212641 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,01432445 0,02211156 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,01432445 0,02209673 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,01432445 0,02208192 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,01432445 0,02206713 ! cellular response to extracellular stimulus GO:0031668 32 21 0,000 0,01432445 0,02205236 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,01432445 0,02203761 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,01432445 0,02202288 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,01432445 0,02200817 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,01432445 0,02199348 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,01432445 0,02197881 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,01432445 0,02196415 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,01432445 0,02194952 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,01432445 0,02193491 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,01432445 0,02192031 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,01432445 0,02190574 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,01500185 0,02292642 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,01500185 0,02291119 ! regulation of fibroblast proliferation GO:0048145 35 22 0,000 0,01500185 0,02289599 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,01500185 0,02288081 ! viral genome replication GO:0019079 29 22 0,000 0,01500185 0,02286564 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,01500185 0,0228505 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,01500185 0,02283538 ! leukocyte adhesion GO:0007159 38 22 0,000 0,01500185 0,02282027 ! molting cycle process GO:0022404 40 22 0,000 0,01500185 0,02280519 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,01500185 0,02279013 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,01500185 0,02277509 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,01500185 0,02276006 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,01500185 0,02274506 ! vasculogenesis GO:0001570 33 22 0,000 0,01500185 0,02273008 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,01500185 0,02271511 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,01500185 0,02270017 GO:0010810|regulation of cell-substrate adhesion, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,01500185 0,02268524 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,01500185 0,02267034 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,01500185 0,02265545 ! lysosome organization GO:0007040 37 22 0,000 0,01500185 0,02264059 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,01500185 0,02262574 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,01500185 0,02261091 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,01500185 0,02259611 ! regulation of behavior GO:0050795 38 22 0,000 0,01500185 0,02258132 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,01500185 0,02256655 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,01500185 0,0225518 ! membrane depolarization GO:0051899 35 22 0,000 0,01500185 0,02253707 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,01500185 0,02252236 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,01500185 0,02250767 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,01500185 0,022493 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,01500185 0,02247834 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,01500185 0,02246371 ! blastocyst development GO:0001824 37 22 0,000 0,01500185 0,02244909 ! neural tube closure GO:0001843 33 22 0,000 0,01500185 0,0224345 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,01500185 0,02241992 ! protein tetramerization GO:0051262 39 22 0,000 0,01500185 0,02240536 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,01567882 0,02340123 ! neuron fate commitment GO:0048663 32 23 0,000 0,01567882 0,02338606 ! embryonic pattern specification GO:0009880 31 23 0,000 0,01567882 0,0233709 ! positive regulation of cell adhesion GO:0045785 37 23 0,000 0,01567882 0,02335576 ! myelination GO:0042552 35 23 0,000 0,01567882 0,02334065 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,01567882 0,02332555 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,01567882 0,02331047 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,01567882 0,02329541 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,01567882 0,02328037 ! ER-nuclear signaling pathway GO:0006984 27 23 0,000 0,01567882 0,02326535 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,01567882 0,02325035 ! vesicle targeting GO:0006903 32 23 0,000 0,01567882 0,02323537 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,01567882 0,02322041 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,01567882 0,02320547 ! osteoblast differentiation GO:0001649 40 23 0,000 0,01567882 0,02319054 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,01567882 0,02317564 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,01567882 0,02316076 ! interaction with host GO:0051701 37 23 0,000 0,01567882 0,02314589 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,01567882 0,02313104 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,01567882 0,02311622 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,01567882 0,02310141 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,01567882 0,02308662 ! negative regulation of phosphorylation GO:0042326 41 23 0,000 0,01567882 0,02307185 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,01567882 0,0230571 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,01567882 0,02304236 ! cell fate determination GO:0001709 45 23 0,000 0,01567882 0,02302765 ! pentose metabolic process GO:0019321 31 23 0,000 0,01567882 0,02301295 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,01567882 0,02299828 ! spermatid development GO:0007286 33 23 0,000 0,01567882 0,02298362 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,01567882 0,02296898 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,01567882 0,02295436 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,01567882 0,02293976 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,01567882 0,02292517 ! telomere organization GO:0032200 32 23 0,000 0,01567882 0,02291061 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,01567882 0,02289606 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,01567882 0,02288153 ! regulation of amine transport GO:0051952 38 23 0,000 0,01567882 0,02286702 ! liver development GO:0001889 40 23 0,000 0,01567882 0,02285253 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,01635537 0,02382353 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,01635537 0,02380845 ! initiation of viral infection GO:0019059 42 24 0,000 0,01635537 0,0237934 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,01635537 0,02377835 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,01635537 0,02376333 ! superoxide metabolic process GO:0006801 32 24 0,000 0,01635537 0,02374833 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,01635537 0,02373335 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! insulin receptor signaling pathway GO:0008286 40 24 0,000 0,01635537 0,02371838 ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,01635537 0,02370344 ! fat cell differentiation GO:0045444 37 24 0,000 0,01635537 0,02368851 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,01635537 0,0236736 ! sperm motility GO:0030317 27 24 0,000 0,01635537 0,02365872 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,01635537 0,02364385 ! vacuole organization GO:0007033 39 24 0,000 0,01635537 0,02362899 ! receptor metabolic process GO:0043112 37 24 0,000 0,01635537 0,02361416 ! neural crest cell development GO:0014032 39 24 0,000 0,01635537 0,02359935 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,01635537 0,02358455 ! primary neural tube formation GO:0014020 35 24 0,000 0,01635537 0,02356977 ! negative regulation of cell development GO:0010721 56 24 0,000 0,01635537 0,02355501 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,01635537 0,02354027 ! base-excision repair GO:0006284 31 24 0,000 0,01635537 0,02352555 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,01635537 0,02351085 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,01635537 0,02349616 ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,01635537 0,0234815 ! glutathione metabolic process GO:0006749 29 24 0,000 0,01635537 0,02346685 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,01635537 0,02345222 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,01635537 0,02343761 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,01635537 0,02342301 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,01703149 0,02437613 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,01703149 0,02436097 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,01703149 0,02434583 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,01703149 0,02433071 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,01703149 0,0243156 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,01703149 0,02430052 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 0,000 0,01703149 0,02428545 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,01703149 0,02427041 ! peptide transport GO:0015833 43 25 0,000 0,01703149 0,02425538 ! male gonad development GO:0008584 33 25 0,000 0,01703149 0,02424037 ! iron ion homeostasis GO:0055072 39 25 0,000 0,01703149 0,02422538 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,01703149 0,02421041 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,01703149 0,02419545 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,01703149 0,02418052 ! phospholipid transport GO:0015914 35 25 0,000 0,01703149 0,0241656 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,01703149 0,0241507 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,01703149 0,02413582 ! detection of light stimulus GO:0009583 30 25 0,000 0,01703149 0,02412096 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,01703149 0,02410612 GO:0045840|positive regulation of mitosis, ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,01703149 0,02409129 ! leukocyte proliferation GO:0070661 39 25 0,000 0,01703149 0,02407648 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,01703149 0,02406169 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,01770719 0,02500094 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,01770719 0,02498561 ! translational initiation GO:0006413 43 26 0,000 0,01770719 0,02497029 ! regulation of pH GO:0006885 36 26 0,000 0,01770719 0,02495499 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 0,000 0,01770719 0,02493971 ! circadian rhythm GO:0007623 42 26 0,000 0,01770719 0,02492444 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,01770719 0,0249092 ! post-embryonic development GO:0009791 42 26 0,000 0,01770719 0,02489397 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,01770719 0,02487876 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,01770719 0,02486358 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,01770719 0,02484841 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,01770719 0,02483326 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,01770719 0,02481812 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,01770719 0,02480301 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,01770719 0,02478791 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,01770719 0,02477283 ! regulation of coagulation GO:0050818 39 26 0,000 0,01770719 0,02475777 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,01838246 0,02568631 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,01838246 0,02567071 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,01838246 0,02565513 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,01838246 0,02563958 ! membrane docking GO:0022406 39 27 0,000 0,01838246 0,02562404 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,01838246 0,02560852 ! catechol metabolic process GO:0009712 43 27 0,000 0,01838246 0,02559301 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,01838246 0,02557753 ! acute-phase response GO:0006953 42 27 0,000 0,01838246 0,02556207 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,01838246 0,02554662 ! myofibril assembly GO:0030239 36 27 0,000 0,01838246 0,0255312 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,01838246 0,02551579 ! response to ionizing radiation GO:0010212 47 27 0,000 0,01838246 0,0255004 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,01838246 0,02548503 ! natural killer cell activation GO:0030101 35 27 0,000 0,01838246 0,02546967 ! lipid oxidation GO:0034440 38 27 0,000 0,01838246 0,02545434 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,01838246 0,02543902 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,01838246 0,02542373 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,01838246 0,02540845 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,01838246 0,02539319 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,01838246 0,02537795 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,01838246 0,02536272 ! gene silencing GO:0016458 41 27 0,000 0,01838246 0,02534752 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,01905731 0,02626231 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,01905731 0,02624659 ! phenol metabolic process GO:0018958 44 28 0,000 0,01905731 0,02623088 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,01905731 0,02621519 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,01905731 0,02619952 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,01905731 0,02618387 ! cell junction assembly GO:0034329 56 28 0,000 0,01905731 0,02616824 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,01905731 0,02615263 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,01905731 0,02613703 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,01905731 0,02612146 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,01905731 0,0261059 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,01905731 0,02609036 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,01905731 0,02607484 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,01905731 0,02605934 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,01905731 0,02604385 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,01905731 0,02602839 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,01905731 0,02601294 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,01905731 0,02599751 ! mesoderm formation GO:0001707 46 28 0,000 0,01905731 0,0259821 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,01905731 0,02596671 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,01905731 0,02595133 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,01905731 0,02593598 ! ensheathment of neurons GO:0007272 43 28 0,000 0,01905731 0,02592064 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,01905731 0,02590532 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,01905731 0,02589002 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,01905731 0,02587474 ! neural tube formation GO:0001841 41 28 0,000 0,01905731 0,02585947 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,01905731 0,02584422 ! placenta development GO:0001890 37 28 0,000 0,01905731 0,02582899 ! regulation of B cell activation GO:0050864 42 28 0,000 0,01905731 0,02581378 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,01973172 0,02671157 ! regulation of innate immune response GO:0045088 38 29 0,000 0,01973172 0,02669586 ! ovulation cycle process GO:0022602 41 29 0,000 0,01973172 0,02668017 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,01973172 0,02666449 ! protein targeting to membrane GO:0006612 53 29 0,000 0,01973172 0,02664883 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,01973172 0,0266332 ! mismatch repair GO:0006298 34 29 0,000 0,01973172 0,02661758 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,01973172 0,02660197 ! muscle cell development GO:0055001 38 29 0,000 0,01973172 0,02658639 ! formation of primary germ layer GO:0001704 48 29 0,000 0,01973172 0,02657082 ! telencephalon development GO:0021537 52 29 0,000 0,01973172 0,02655528 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,01973172 0,02653975 ! eye morphogenesis GO:0048592 51 29 0,000 0,01973172 0,02652423 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,01973172 0,02650874 ! tissue homeostasis GO:0001894 42 29 0,000 0,01973172 0,02649327 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,02040572 0,02738224 ! collagen metabolic process GO:0032963 40 30 0,000 0,02040572 0,02736627 ! organic anion transport GO:0015711 51 30 0,000 0,02040572 0,02735032 ! cholesterol transport GO:0030301 46 30 0,000 0,02040572 0,02733439 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,02040572 0,02731848 ! spliceosome assembly GO:0000245 49 30 0,000 0,02040572 0,02730259 ! spindle organization GO:0007051 37 30 0,000 0,02040572 0,02728672 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,02040572 0,02727086 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,02040572 0,02725502 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,02040572 0,02723921 ! ceramide metabolic process GO:0006672 43 30 0,000 0,02040572 0,02722341 ! ovulation cycle GO:0042698 43 30 0,000 0,02040572 0,02720762 ! hindbrain development GO:0030902 45 30 0,000 0,02040572 0,02719186 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,02040572 0,02717612 ! adult locomotory behavior GO:0008344 47 30 0,000 0,02040572 0,02716039 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,02040572 0,02714468 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,02040572 0,02712899 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,02040572 0,02711332 ! response to heat GO:0009408 41 30 0,000 0,02040572 0,02709766 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,02040572 0,02708203 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,02040572 0,02706641 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,02107929 0,02794372 ! negative regulation of secretion GO:0051048 49 31 0,000 0,02107929 0,02792763 ! mammary gland development GO:0030879 57 31 0,000 0,02107929 0,02791155 ! glial cell differentiation GO:0010001 55 31 0,000 0,02107929 0,02789549 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,02107929 0,02787945 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,02107929 0,02786343 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,02107929 0,02784742 ! odontogenesis GO:0042476 50 31 0,000 0,02107929 0,02783144 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,02107929 0,02781547 ! segmentation GO:0035282 41 31 0,000 0,02107929 0,02779952 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,02107929 0,02778359 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,02107929 0,02776768 ! metanephros development GO:0001656 58 31 0,000 0,02107929 0,02775178 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,02107929 0,0277359 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,02107929 0,02772005 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,02107929 0,02770421 ! cell fate specification GO:0001708 37 31 0,000 0,02107929 0,02768838 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,02107929 0,02767258 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,02107929 0,0276568 ! RNA modification GO:0009451 40 31 0,000 0,02107929 0,02764103 ! regulation of muscle development GO:0048634 48 32 0,000 0,02175243 0,02850746 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,02175243 0,02849123 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,02175243 0,02847501 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,02175243 0,02845881 ! meiosis I GO:0007127 52 32 0,000 0,02175243 0,02844263 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,02175243 0,02842647 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,02175243 0,02841033 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,02175243 0,02839421 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,02175243 0,0283781 ! peripheral nervous system development GO:0007422 53 32 0,000 0,02175243 0,02836202 ! regulation of protein stability GO:0031647 48 32 0,000 0,02175243 0,02834595 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,02175243 0,02832989 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,02175243 0,02831386 ! cytokine production GO:0001816 44 32 0,000 0,02175243 0,02829785 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,02175243 0,02828185 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,02175243 0,02826587 ! vesicle localization GO:0051648 47 32 0,000 0,02175243 0,02824991 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,02242515 0,02910714 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,02242515 0,02909072 ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,02242515 0,02907432 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,02242515 0,02905794 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,02242515 0,02904158 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,02242515 0,02902524 ! sister chromatid segregation GO:0000819 46 33 0,000 0,02242515 0,02900892 ! ear morphogenesis GO:0042471 42 33 0,000 0,02242515 0,02899261 ! actomyosin structure organization GO:0031032 43 33 0,000 0,02242515 0,02897632 ! cell junction organization GO:0034330 63 33 0,000 0,02242515 0,02896005 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,02242515 0,0289438 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,02242515 0,02892757 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,02242515 0,02891135 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 0,000 0,02242515 0,02889515 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,02242515 0,02887898 ! female gonad development GO:0008585 49 33 0,000 0,02242515 0,02886282 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,02242515 0,02884667 ! positive regulation of cell development GO:0010720 54 33 0,000 0,02242515 0,02883055 ! lipid homeostasis GO:0055088 55 33 0,000 0,02242515 0,02881444 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,02242515 0,02879835 ! regulation of proteolysis GO:0030162 50 33 0,000 0,02242515 0,02878228 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,02242515 0,02876623 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,02242515 0,0287502 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,02242515 0,02873418 ! cytokinesis GO:0000910 52 33 0,000 0,02242515 0,02871818 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,02242515 0,0287022 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,02309745 0,02954624 ! mRNA catabolic process GO:0006402 48 34 0,000 0,02309745 0,02952981 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,02309745 0,02951341 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,02309745 0,02949702 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,02309745 0,02948065 ! feeding behavior GO:0007631 45 34 0,000 0,02309745 0,0294643 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,02309745 0,02944797 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,02309745 0,02943165 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,02309745 0,02941536 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,02309745 0,02939908 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,02309745 0,02938282 ! neuron migration GO:0001764 46 34 0,000 0,02309745 0,02936657 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,02309745 0,02935035 ! female gamete generation GO:0007292 43 34 0,000 0,02309745 0,02933414 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,02309745 0,02931795 ! polyol metabolic process GO:0019751 44 34 0,000 0,02309745 0,02930178 ! aerobic respiration GO:0009060 47 34 0,000 0,02309745 0,02928563 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,02309745 0,02926949 ! cellular response to insulin stimulus GO:0032869 52 34 0,000 0,02309745 0,02925338 ! embryonic organ development GO:0048568 45 34 0,000 0,02309745 0,02923728 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,02309745 0,0292212 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,02376932 0,03005467 ! Notch signaling pathway GO:0007219 56 35 0,000 0,02376932 0,03003815 ! regulation of intracellular protein transport GO:0033157 59 35 0,000 0,02376932 0,03002166 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,02376932 0,03000518 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,02376932 0,02998872 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,02376932 0,02997228 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,02376932 0,02995586 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,02376932 0,02993945 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,02376932 0,02992306 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,02376932 0,0299067 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,02376932 0,02989034 ! glycogen metabolic process GO:0005977 48 35 0,000 0,02376932 0,02987401 ! pigment metabolic process GO:0042440 61 35 0,000 0,02376932 0,02985769 ! positive regulation of leukocyte proliferation GO:0070665 50 35 0,000 0,02376932 0,0298414 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! protein homooligomerization GO:0051260 52 35 0,000 0,02376932 0,02982512 ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,02444077 0,03065091 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 0,000 0,02444077 0,03063421 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,02444077 0,03061752 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,02444077 0,03060086 ! negative regulation of binding GO:0051100 58 36 0,000 0,02444077 0,03058421 ! organic ether metabolic process GO:0018904 46 36 0,000 0,02444077 0,03056758 ! tissue remodeling GO:0048771 62 36 0,000 0,02444077 0,03055096 ! neural tube development GO:0021915 50 36 0,000 0,02444077 0,03053437 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,02444077 0,03051779 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,02444077 0,03050123 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,02444077 0,03048469 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,02444077 0,03046817 ! glucan metabolic process GO:0044042 49 36 0,000 0,02444077 0,03045166 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,0251118 0,03127078 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,0251118 0,03125386 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,0251118 0,03123696 ! learning GO:0007612 67 37 0,000 0,0251118 0,03122007 ! ion transmembrane transport GO:0034220 56 37 0,000 0,0251118 0,0312032 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,0251118 0,03118636 ! regulation of protein secretion GO:0050708 51 37 0,000 0,0251118 0,03116953 ! amino acid activation GO:0043038 52 37 0,000 0,0251118 0,03115271 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,0251118 0,03113592 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,0257824 0,03195017 ! gliogenesis GO:0042063 71 38 0,000 0,0257824 0,03193296 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,0257824 0,03191578 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,0257824 0,03189861 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,0257824 0,03188146 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,0257824 0,03186433 ! phagocytosis GO:0006909 60 38 0,000 0,0257824 0,03184722 ! mesenchymal cell development GO:0014031 64 38 0,000 0,0257824 0,03183012 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 0,000 0,0257824 0,03181305 ! maintenance of location in cell GO:0051651 69 38 0,000 0,0257824 0,03179599 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,02645258 0,032605 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,02645258 0,03258754 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,02645258 0,03257009 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,02645258 0,03255266 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,02645258 0,03253526 ! regulation of epithelial cell proliferation GO:0050678 71 39 0,000 0,02645258 0,03251787 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,02645258 0,0325005 ! male sex differentiation GO:0046661 53 39 0,000 0,02645258 0,03248314 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,02645258 0,03246581 ! chromatin remodeling GO:0006338 68 39 0,000 0,02645258 0,0324485 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,02645258 0,0324312 ! JNK cascade GO:0007254 54 39 0,000 0,02645258 0,03241392 ! developmental growth GO:0048589 62 39 0,000 0,02645258 0,03239666 ! cell growth GO:0016049 61 39 0,000 0,02645258 0,03237942 ! synapse organization GO:0050808 55 39 0,000 0,02645258 0,0323622 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,02712233 0,03316394 ! response to calcium ion GO:0051592 58 40 0,000 0,02712233 0,03314632 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,02712233 0,03312871 ! regulation of tube size GO:0035150 60 40 0,000 0,02712233 0,03311113 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,02712233 0,03309356 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,02712233 0,03307602 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,02712233 0,03305849 ! peptide metabolic process GO:0006518 56 40 0,000 0,02712233 0,03304098 ! induction of apoptosis by intracellular signals GO:0008629 67 40 0,000 0,02712233 0,03302349 ! inner ear development GO:0048839 57 40 0,000 0,02712233 0,03300602 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,02712233 0,03298856 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,02712233 0,03297113 ! double-strand break repair GO:0006302 67 40 0,000 0,02712233 0,03295371 ! B cell differentiation GO:0030183 62 40 0,000 0,02712233 0,03293631 ! epidermal cell differentiation GO:0009913 53 40 0,000 0,02712233 0,03291893 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,02712233 0,03290157 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,02712233 0,03288422 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,02712233 0,0328669 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,02779167 0,03366026 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,02779167 0,03364255 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,02779167 0,03362485 ! glucose transport GO:0015758 52 41 0,000 0,02779167 0,03360717 ! endosome transport GO:0016197 71 41 0,000 0,02779167 0,03358951 ! striated muscle contraction GO:0006941 62 41 0,000 0,02779167 0,03357187 ! positive regulation of DNA binding GO:0043388 57 41 0,000 0,02779167 0,03355425 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,02779167 0,03353664 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,02779167 0,03351906 ! biopolymer methylation GO:0043414 62 41 0,000 0,02779167 0,03350149 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,02779167 0,03348394 ! mitochondrial transport GO:0006839 60 42 0,000 0,02846058 0,0342719 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,02846058 0,03425397 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 0,000 0,02846058 0,03423606 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,02846058 0,03421816 ! cellular component disassembly GO:0022411 64 42 0,000 0,02846058 0,03420028 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,02846058 0,03418242 ! hexose transport GO:0008645 54 42 0,000 0,02846058 0,03416458 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,02846058 0,03414676 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,02846058 0,03412896 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,02846058 0,03411117 ! excretion GO:0007588 63 42 0,000 0,02846058 0,0340934 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,02846058 0,03407566 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,02846058 0,03405793 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,02846058 0,03404022 ! regulation of cell shape GO:0008360 78 42 0,000 0,02846058 0,03402252 ! positive regulation of binding GO:0051099 59 43 0,000 0,02912907 0,03480357 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 0,000 0,02912907 0,0347855 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,02912907 0,03476744 ! leukocyte migration GO:0050900 60 43 0,000 0,02912907 0,03474941 ! neuromuscular process GO:0050905 79 43 0,000 0,02912907 0,0347314 ! activation of caspase activity GO:0006919 65 43 0,000 0,02912907 0,0347134 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,02912907 0,03469542 ! tRNA processing GO:0008033 49 43 0,000 0,02912907 0,03467747 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,02912907 0,03465953 ! vesicle organization GO:0016050 79 43 0,000 0,02912907 0,03464161 ! response to insulin stimulus GO:0032868 63 43 0,000 0,02912907 0,0346237 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,02912907 0,03460582 ! methylation GO:0032259 64 43 0,000 0,02912907 0,03458795 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,02979714 0,03536296 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,02979714 0,03534473 ! glycolysis GO:0006096 53 44 0,000 0,02979714 0,03532651 ! regulation of action potential GO:0001508 71 44 0,000 0,02979714 0,03530831 ! regulation of ion transport GO:0043269 57 44 0,000 0,02979714 0,03529013 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,02979714 0,03527196 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,02979714 0,03525382 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,02979714 0,03523569 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,02979714 0,03521759 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,02979714 0,0351995 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,02979714 0,03518143 ! regulation of mast cell proliferation GO:0070666 64 44 0,000 0,02979714 0,03516338 ! positive regulation of cell cycle GO:0045787 77 45 0,000 0,03046479 0,03593283 ! RNA catabolic process GO:0006401 64 45 0,000 0,03046479 0,03591441 ! positive regulation of defense response GO:0031349 59 45 0,000 0,03046479 0,03589601 ! regulation of translational initiation GO:0006446 64 45 0,000 0,03046479 0,03587763 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,03046479 0,03585927 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,03046479 0,03584093 ! cell recognition GO:0008037 58 45 0,000 0,03046479 0,0358226 ! cell maturation GO:0048469 60 45 0,000 0,03046479 0,0358043 ! protein amino acid autophosphorylation GO:0046777 80 45 0,000 0,03046479 0,03578601 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,03113201 0,03655111 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,03113201 0,03653247 ! cell redox homeostasis GO:0045454 63 46 0,000 0,03113201 0,03651384 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,03113201 0,03649523 ! regulation of ossification GO:0030278 71 46 0,000 0,03113201 0,03647663 ! histone modification GO:0016570 68 46 0,000 0,03113201 0,03645806 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,03113201 0,03643951 ! response to UV GO:0009411 75 46 0,000 0,03113201 0,03642097 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,03179882 0,03718215 ! viral infectious cycle GO:0019058 71 47 0,000 0,03179882 0,03716325 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,03179882 0,03714438 ! endocrine system development GO:0035270 83 47 0,000 0,03179882 0,03712553 ! covalent chromatin modification GO:0016569 75 47 0,000 0,03179882 0,03710669 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,03179882 0,03708787 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,03179882 0,03706907 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,03179882 0,0370503 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,03179882 0,03703154 ! regulation of leukocyte proliferation GO:0070663 71 47 0,000 0,03179882 0,0370128 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,03179882 0,03699407 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,03179882 0,03697537 ! chloride transport GO:0006821 67 48 0,000 0,0324652 0,03773116 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,0324652 0,03771211 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 0,000 0,0324652 0,03769307 ! response to temperature stimulus GO:0009266 62 48 0,000 0,0324652 0,03767405 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,0324652 0,03765505 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,0324652 0,03763607 ! gastrulation GO:0007369 73 48 0,000 0,0324652 0,03761711 ! heart morphogenesis GO:0003007 65 48 0,000 0,0324652 0,03759817 ! regulation of DNA replication GO:0006275 75 48 0,000 0,0324652 0,03757925 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,0324652 0,03756035 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,0324652 0,03754146 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,0324652 0,0375226 ! regulation of endocytosis GO:0030100 63 48 0,000 0,0324652 0,03750375 ! nuclear export GO:0051168 69 48 0,000 0,0324652 0,03748492 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,0324652 0,03746612 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,0324652 0,03744733 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,03313117 0,03819633 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,03313117 0,0381772 ! sensory perception of smell GO:0007608 61 49 0,000 0,03313117 0,03815808 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,03313117 0,03813898 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,03313117 0,0381199 ! RNA elongation GO:0006354 62 49 0,000 0,03313117 0,03810084 ! regulation of intracellular transport GO:0032386 78 49 0,000 0,03313117 0,0380818 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,03313117 0,03806278 ! germ cell development GO:0007281 68 49 0,000 0,03313117 0,03804378 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,03313117 0,03802479 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,03313117 0,03800583 ! cartilage development GO:0051216 70 49 0,000 0,03313117 0,03798688 ! maintenance of location GO:0051235 84 49 0,000 0,03313117 0,03796796 ! regulation of actin filament length GO:0030832 72 50 0,000 0,03379671 0,03871137 ! ear development GO:0043583 72 50 0,000 0,03379671 0,0386921 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,03379671 0,03867285 ! membrane fusion GO:0006944 80 50 0,000 0,03379671 0,03865362 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,03379671 0,03863441 ! lipid modification GO:0030258 73 50 0,000 0,03379671 0,03861522 ! positive regulation of growth GO:0045927 67 50 0,000 0,03379671 0,03859605 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,03379671 0,03857689 ! proton transport GO:0015992 75 50 0,000 0,03379671 0,03855776 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,03379671 0,03853864 ! positive regulation of secretion GO:0051047 71 51 0,000 0,03446184 0,03927761 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 0,000 0,03446184 0,03925816 ! hydrogen transport GO:0006818 77 51 0,000 0,03446184 0,03923872 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,03446184 0,03921931 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 0,000 0,03446184 0,03919991 ! positive regulation of cell migration GO:0030335 92 51 0,000 0,03446184 0,03918053 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,03446184 0,03916118 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,03446184 0,03914184 ! adult behavior GO:0030534 80 51 0,000 0,03446184 0,03912252 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,03446184 0,03910322 ! transition metal ion transport GO:0000041 74 52 0,000 0,03512654 0,03983779 ! regulation of cellular component size GO:0032535 74 52 0,000 0,03512654 0,03981816 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,03512654 0,03979854 ! aging GO:0007568 79 52 0,000 0,03512654 0,03977895 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,03512654 0,03975937 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,03512654 0,03973981 ! establishment of organelle localization GO:0051656 85 52 0,000 0,03512654 0,03972028 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,03579082 0,04045155 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,03579082 0,04043168 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,03579082 0,04041183 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,03579082 0,040392 ! kidney development GO:0001822 90 53 0,000 0,03579082 0,04037219 ! single fertilization GO:0007338 59 53 0,000 0,03579082 0,0403524 ! cell projection assembly GO:0030031 76 53 0,000 0,03579082 0,04033263 ! amino acid transport GO:0006865 84 54 0,000 0,03645469 0,04106062 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,03645469 0,04104052 ! regulation of mitosis GO:0007088 84 54 0,000 0,03645469 0,04102044 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,03645469 0,04100038 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,03645469 0,04098035 ! DNA catabolic process GO:0006308 67 54 0,000 0,03645469 0,04096033 ! detection of external stimulus GO:0009581 66 54 0,000 0,03645469 0,04094033 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,03645469 0,04092034 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,03645469 0,04090038 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,03645469 0,04088044 ! exocytosis GO:0006887 74 55 0,000 0,03711814 0,04160415 ! mesoderm development GO:0007498 76 55 0,000 0,03711814 0,04158388 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,03711814 0,04156364 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,03711814 0,04154341 ! DNA damage response, signal transduction GO:0042770 96 56 0,000 0,03778116 0,04226492 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,03778116 0,04224437 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,03778116 0,04222385 ! positive regulation of cell motion GO:0051272 99 56 0,000 0,03778116 0,04220334 ! negative regulation of protein kinase activity GO:0006469 99 57 0,000 0,03844377 0,04292266 ! carbohydrate transport GO:0008643 74 57 0,000 0,03844377 0,04290183 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,03844377 0,04288103 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 0,000 0,03844377 0,04286024 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,03844377 0,04283948 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,03844377 0,04281873 ! camera-type eye development GO:0043010 88 57 0,000 0,03844377 0,042798 ! secondary metabolic process GO:0019748 84 57 0,000 0,03844377 0,0427773 ! response to peptide hormone stimulus GO:0043434 84 57 0,000 0,03844377 0,04275661 ! developmental maturation GO:0021700 75 57 0,000 0,03844377 0,04273595 ! gonad development GO:0008406 79 57 0,000 0,03844377 0,0427153 ! negative regulation of kinase activity GO:0033673 100 58 0,000 0,03910596 0,04343009 ! viral reproductive process GO:0022415 87 58 0,000 0,03910596 0,04340913 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,03910596 0,04338819 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,03910596 0,04336727 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,03910596 0,04334637 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,03976774 0,04405867 ! activation of MAPK activity GO:0000187 84 59 0,000 0,03976774 0,04403745 ! lung development GO:0030324 94 59 0,000 0,03976774 0,04401626 ! actin filament organization GO:0007015 95 59 0,000 0,03976774 0,04399509 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,03976774 0,04397394 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,03976774 0,04395281 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,04042909 0,0446623 ! phosphoinositide metabolic process GO:0030384 87 60 0,000 0,04042909 0,04464086 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,04042909 0,04461944 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,04042909 0,04459804 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,04042909 0,04457666 ! regulation of heart contraction GO:0008016 91 60 0,000 0,04042909 0,0445553 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,04042909 0,04453396 ! fertilization GO:0009566 68 60 0,000 0,04042909 0,04451264 ! regulation of homeostatic process GO:0032844 105 60 0,000 0,04042909 0,04449134 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,04109003 0,04519707 ! meiosis GO:0007126 96 61 0,000 0,04109003 0,04517546 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 114 61 0,000 0,04109003 0,04515388 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,04109003 0,04513231 ! urogenital system development GO:0001655 101 61 0,000 0,04109003 0,04511077 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,04109003 0,04508925 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,04109003 0,04506775 ! extracellular matrix organization GO:0030198 103 61 0,000 0,04109003 0,04504627 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,04109003 0,04502481 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! negative regulation of transferase activity GO:0051348 105 61 0,000 0,04109003 0,04500336 ! amine catabolic process GO:0009310 90 62 0,000 0,04175055 0,04570503 ! neurotransmitter transport GO:0006836 81 62 0,000 0,04175055 0,04568328 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,04175055 0,04566156 ! negative regulation of cell growth GO:0030308 106 62 0,000 0,04175055 0,04563986 ! respiratory tube development GO:0030323 99 62 0,000 0,04175055 0,04561818 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,04175055 0,04559652 ! meiotic cell cycle GO:0051321 97 62 0,000 0,04175055 0,04557488 ! organelle localization GO:0051640 96 62 0,000 0,04175055 0,04555326 ! regulation of transcription factor activity GO:0051090 97 63 0,000 0,04241065 0,04625154 GO:0090046|regulation of transcription regulator activity, ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,04241065 0,04622962 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 0,000 0,04241065 0,04620772 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 0,000 0,04241065 0,04618584 ! viral reproduction GO:0016032 92 63 0,000 0,04241065 0,04616398 ! regulation of lipase activity GO:0060191 109 63 0,000 0,04241065 0,04614215 ! cell cycle checkpoint GO:0000075 108 64 0,000 0,04307034 0,04683772 ! negative regulation of cell size GO:0045792 108 64 0,000 0,04307034 0,04681558 ! appendage morphogenesis GO:0035107 93 64 0,000 0,04307034 0,04679347 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,04307034 0,04677138 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,04307034 0,0467493 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 0,000 0,04307034 0,04672725 ! hexose catabolic process GO:0019320 82 64 0,000 0,04307034 0,04670522 ! respiratory system development GO:0060541 100 64 0,000 0,04307034 0,04668321 ! adaptive immune response GO:0002250 94 64 0,000 0,04307034 0,04666122 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 90 65 0,000 0,04372961 0,04735315 ! regulation of caspase activity GO:0043281 97 65 0,000 0,04372961 0,04733087 ! appendage development GO:0048736 94 65 0,000 0,04372961 0,04730861 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 0,000 0,04372961 0,04728636 ! defense response to bacterium GO:0042742 73 65 0,000 0,04372961 0,04726414 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,04372961 0,04724194 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,04372961 0,04721976 ! activation of immune response GO:0002253 83 65 0,000 0,04372961 0,04719761 ! protein oligomerization GO:0051259 100 65 0,000 0,04372961 0,04717547 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,04438846 0,04786379 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,04438846 0,04784136 ! antigen processing and presentation GO:0019882 96 66 0,000 0,04438846 0,04781895 ! axon guidance GO:0007411 99 66 0,000 0,04438846 0,04779656 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,04438846 0,0477742 ! regulation of immune effector process GO:0002697 101 66 0,000 0,04438846 0,04775185 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,0450469 0,04843752 ! regulation of endopeptidase activity GO:0052548 99 67 0,000 0,0450469 0,04841489 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,0450469 0,04839228 ! acute inflammatory response GO:0002526 92 68 0,000 0,04570492 0,04907624 ! learning or memory GO:0007611 123 68 0,000 0,04570492 0,04905334 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,04570492 0,04903046 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,04570492 0,04900761 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,04570492 0,04898477 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,04570492 0,04896195 ! rhythmic process GO:0048511 105 68 0,000 0,04570492 0,04893916 ! inorganic anion transport GO:0015698 93 68 0,000 0,04570492 0,04891639 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,04636252 0,04959712 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,04636252 0,04957406 ! response to drug GO:0042493 108 69 0,000 0,04636252 0,04955102 ! response to metal ion GO:0010038 103 70 0,000 0,04701971 0,05023007 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,04701971 0,05020675 ! humoral immune response GO:0006959 86 70 0,000 0,04701971 0,05018345 ! eye development GO:0001654 111 70 0,000 0,04701971 0,05016018 ! amine transport GO:0015837 101 70 0,000 0,04701971 0,05013692 ! positive regulation of phosphorylation GO:0042327 102 70 0,000 0,04701971 0,05011369 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,04701971 0,05009048 ! regulation of catabolic process GO:0009894 106 70 0,000 0,04701971 0,05006729 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,04767649 0,05074314 ! muscle cell differentiation GO:0042692 104 71 0,000 0,04767649 0,05071967 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,04767649 0,05069622 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,04767649 0,05067279 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,04767649 0,05064939 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,04767649 0,050626 ! regulation of peptidase activity GO:0052547 106 72 0,000 0,04833285 0,05129929 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 0,000 0,04833285 0,05127562 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 132 72 0,000 0,04833285 0,05125198 ! negative regulation of organelle organization GO:0010639 115 72 0,000 0,04833285 0,05122837 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,04833285 0,05120477 ! negative regulation of transport GO:0051051 116 73 0,000 0,04898879 0,05187579 ! regulation of blood pressure GO:0008217 107 73 0,000 0,04898879 0,05185192 ! tube morphogenesis GO:0035239 118 73 0,000 0,04898879 0,05182807 ! mitochondrion organization GO:0007005 104 73 0,000 0,04898879 0,05180424 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,04898879 0,05178043 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,04898879 0,05175665 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,04964432 0,05242514 ! response to oxygen levels GO:0070482 137 74 0,000 0,04964432 0,05240108 ! digestion GO:0007586 97 74 0,000 0,04964432 0,05237704 ! protein import into nucleus GO:0006606 118 74 0,000 0,04964432 0,05235302 ! cellular response to hormone stimulus GO:0032870 109 74 0,000 0,04964432 0,05232903 ! positive regulation of lymphocyte activation GO:0051251 108 74 0,000 0,04964432 0,05230506 ! blood coagulation GO:0007596 116 75 0,000 0,05029944 0,05297102 GO:0050817|coagulation, ! response to inorganic substance GO:0010035 115 75 0,000 0,05029944 0,05294678 ! negative regulation of growth GO:0045926 123 75 0,000 0,05029944 0,05292256 ! response to nutrient GO:0007584 104 75 0,000 0,05029944 0,05289836 ! nuclear import GO:0051170 121 75 0,000 0,05029944 0,05287418 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,05029944 0,05285003 ! amine biosynthetic process GO:0009309 97 76 0,000 0,05095414 0,05351348 ! tRNA metabolic process GO:0006399 95 76 0,000 0,05095414 0,05348906 ! response to unfolded protein GO:0006986 99 76 0,000 0,05095414 0,05346466 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,05095414 0,05344028 ! regulation of protein transport GO:0051223 114 76 0,000 0,05095414 0,05341592 GO:0070201|regulation of establishment of protein localization, ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,05160843 0,05407717 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,05160843 0,05405255 ! regulation of DNA binding GO:0051101 119 77 0,000 0,05160843 0,05402794 ! gland development GO:0048732 148 77 0,000 0,05160843 0,05400336 ! sex differentiation GO:0007548 105 77 0,000 0,05160843 0,05397881 ! protein ubiquitination GO:0016567 125 77 0,000 0,05160843 0,05395427 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,05160843 0,05392976 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,05160843 0,05390527 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,05160843 0,0538808 ! positive regulation of protein modification process GO:0031401 107 78 0,000 0,05226231 0,05453871 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,05226231 0,05451397 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,05226231 0,05448926 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,05291577 0,05514557 ! cellular respiration GO:0045333 107 79 0,000 0,05291577 0,05512059 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,05291577 0,05509564 ! T cell activation GO:0042110 134 79 0,000 0,05291577 0,05507071 ! regulation of lyase activity GO:0051339 133 79 0,000 0,05291577 0,0550458 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,05291577 0,05502092 ! chromatin assembly GO:0031497 102 80 0,000 0,05356882 0,05567478 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,05356882 0,05564963 ! protein localization in nucleus GO:0034504 133 80 0,000 0,05356882 0,05562451 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,05356882 0,05559941 ! forebrain development GO:0030900 131 80 0,000 0,05356882 0,05557433 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,05422145 0,05622604 ! hemostasis GO:0007599 125 81 0,000 0,05422145 0,0562007 ! mRNA transport GO:0051028 121 81 0,000 0,05422145 0,05617538 ! regulation of cell cycle process GO:0010564 122 81 0,000 0,05422145 0,05615009 ! response to protein stimulus GO:0051789 111 81 0,000 0,05422145 0,05612482 ! regulation of neurological system process GO:0031644 122 81 0,000 0,05422145 0,05609957 ! vitamin metabolic process GO:0006766 103 81 0,000 0,05422145 0,05607435 ! positive regulation of cell activation GO:0050867 120 81 0,000 0,05422145 0,05604914 GO:0002696|positive regulation of leukocyte activation, ! ossification GO:0001503 134 82 0,000 0,05487368 0,05669787 GO:0060348|bone development, ! detection of stimulus GO:0051606 108 82 0,000 0,05487368 0,05667241 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,05552549 0,05731985 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,05552549 0,05729413 ! regulation of cell adhesion GO:0030155 159 83 0,000 0,05552549 0,05726844 ! regulation of defense response GO:0031347 117 84 0,000 0,05617689 0,05791432 ! microtubule cytoskeleton organization GO:0000226 120 84 0,000 0,05617689 0,05788837 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,05617689 0,05786245 ! sterol metabolic process GO:0016125 120 84 0,000 0,05617689 0,05783655 ! regulation of DNA metabolic process GO:0051052 135 85 0,000 0,05682788 0,05848059 ! rRNA metabolic process GO:0016072 107 85 0,000 0,05682788 0,05845443 GO:0006364|rRNA processing, ! positive regulation of MAP kinase activity GO:0043406 121 85 0,000 0,05682788 0,0584283 ! transcription initiation GO:0006352 118 85 0,000 0,05682788 0,0584022 ! anterior/posterior pattern formation GO:0009952 124 85 0,000 0,05682788 0,05837611 ! regulation of protein localization GO:0032880 132 85 0,000 0,05682788 0,05835005 ! regulation of membrane potential GO:0042391 128 85 0,000 0,05682788 0,05832401 ! negative regulation of multicellular organismal process GO:0051241 133 85 0,000 0,05682788 0,058298 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,05747845 0,05893912 ! cell cycle arrest GO:0007050 150 86 0,000 0,05747845 0,05891285 ! nucleosome organization GO:0034728 114 87 0,000 0,05812862 0,0595527 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,05812862 0,05952619 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,05812862 0,0594997 ! skeletal muscle tissue development GO:0007519 123 87 0,000 0,05812862 0,05947323 GO:0060538|skeletal muscle organ development, ! female pregnancy GO:0007565 130 87 0,000 0,05812862 0,05944678 ! Wnt receptor signaling pathway GO:0016055 130 87 0,000 0,05812862 0,05942036 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,05877837 0,06005786 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,05877837 0,06003119 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,05877837 0,06000455 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,05877837 0,05997793 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 0,000 0,05877837 0,05995133 ! regulation of neurogenesis GO:0050767 153 89 0,000 0,05942771 0,06058676 ! reproductive developmental process GO:0003006 127 89 0,000 0,05942771 0,06055992 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,05942771 0,0605331 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,05942771 0,0605063 ! regulation of T cell activation GO:0050863 128 89 0,000 0,05942771 0,06047953 ! leukocyte differentiation GO:0002521 143 90 0,000 0,06007664 0,06111291 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,06007664 0,06108589 ! hormone metabolic process GO:0042445 121 90 0,000 0,06007664 0,0610589 ! RNA localization GO:0006403 135 91 0,000 0,06072516 0,06169076 ! ATP metabolic process GO:0046034 137 91 0,000 0,06072516 0,06166352 ! response to virus GO:0009615 122 91 0,000 0,06072516 0,06163631 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,06137328 0,06226667 ! glycerophospholipid metabolic process GO:0006650 130 92 0,000 0,06137328 0,06223921 ! cell fate commitment GO:0045165 141 92 0,000 0,06137328 0,06221178 ! positive regulation of immune response GO:0050778 121 92 0,000 0,06137328 0,06218438 ! DNA recombination GO:0006310 146 92 0,000 0,06137328 0,06215699 ! sulfur metabolic process GO:0006790 118 92 0,000 0,06137328 0,06212964 ! regulation of cytoskeleton organization GO:0051493 154 93 0,000 0,06202098 0,0627577 ! peptidyl-amino acid modification GO:0018193 147 93 0,000 0,06202098 0,0627301 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,06202098 0,06270253 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,06202098 0,06267498 ! electron transport chain GO:0022900 123 94 0,000 0,06266827 0,06330128 ! response to oxidative stress GO:0006979 141 94 0,000 0,06266827 0,06327349 ! regulation of binding GO:0051098 151 95 0,000 0,06331515 0,06389857 ! angiogenesis GO:0001525 149 95 0,000 0,06331515 0,06387055 ! carboxylic acid transport GO:0046942 147 95 0,000 0,06331515 0,06384254 GO:0015849|organic acid transport, ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,06396162 0,06446614 ! in utero embryonic development GO:0001701 147 96 0,000 0,06396162 0,0644379 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,06396162 0,06440969 ! regulation of cellular component biogenesis GO:0044087 158 96 0,000 0,06396162 0,0643815 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,06396162 0,06435334 ! protein maturation GO:0051604 129 96 0,000 0,06396162 0,0643252 ! response to light stimulus GO:0009416 153 96 0,000 0,06396162 0,06429709 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,06460769 0,06491816 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! calcium ion transport GO:0006816 167 99 0,000 0,06589859 0,06618635 ! extracellular structure organization GO:0043062 156 99 0,000 0,06589859 0,06615746 ! protein import GO:0017038 156 99 0,000 0,06589859 0,0661286 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 0,000 0,06589859 0,06609976 ! regulation of translation GO:0006417 151 100 0,000 0,06654342 0,06671747 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,06654342 0,0666884 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,06654342 0,06665935 ! divalent metal ion transport GO:0070838 171 100 0,000 0,06654342 0,06663033 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,06654342 0,06660134 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,06654342 0,06657237 ! protein localization in organelle GO:0033365 161 100 0,000 0,06654342 0,06654342