pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-b1/out-0.05-06-0.01-300-run-b1//th1-pval-1e-01-08-th2-pval-1e-02-02-th3-pval-1e-01-01-run-b1/go_data/80145-9-real-Loi_GPL570-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 2,000 5,069E-08 1,238E-04 ! interphase of mitotic cell cycle GO:0051329 224 98 3,000 1,258E-07 1,536E-04 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 2,000 1,362E-06 1,109E-03 ! positive regulation of cell cycle GO:0045787 96 48 2,000 1,551E-06 9,472E-04 ! positive regulation of viral genome replication GO:0045070 9 5 1,000 2,151E-06 1,051E-03 ! meiotic chromosome segregation GO:0045132 10 5 1,000 2,151E-06 8,759E-04 ! nucleotide-excision repair GO:0006289 91 57 2,000 2,617E-06 9,132E-04 ! regulation of retroviral genome replication GO:0045091 8 6 1,000 3,226E-06 9,851E-04 ! establishment of spindle localization GO:0051293 16 6 1,000 3,226E-06 8,757E-04 GO:0051653|spindle localization, ! chromosome segregation GO:0007059 127 67 2,000 4,271E-06 1,043E-03 ! phosphoinositide-mediated signaling GO:0048015 141 75 2,000 6,007E-06 1,334E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 6,018E-06 1,225E-03 ! DNA topological change GO:0006265 12 8 1,000 6,018E-06 1,131E-03 ! DNA synthesis during DNA repair GO:0000731 18 9 1,000 7,736E-06 1,35E-03 ! DNA ligation GO:0006266 18 10 1,000 9,667E-06 1,574E-03 ! positive regulation of viral reproduction GO:0048524 19 10 1,000 9,667E-06 1,476E-03 ! histone deacetylation GO:0016575 24 15 1,000 2,252E-05 3,237E-03 ! negative regulation of cell cycle process GO:0010948 35 17 1,000 2,916E-05 3,957E-03 ! regulation of viral genome replication GO:0045069 30 18 1,000 3,279E-05 4,217E-03 ! protein amino acid deacetylation GO:0006476 34 20 1,000 4,07E-05 4,972E-03 ! cellular response to unfolded protein GO:0034620 35 20 1,000 4,07E-05 4,735E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! apoptotic nuclear changes GO:0030262 34 22 1,000 4,946E-05 5,492E-03 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 1,000 4,946E-05 5,253E-03 ! regulation of viral reproduction GO:0050792 41 24 1,000 5,906E-05 6,011E-03 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 1,000 6,417E-05 6,271E-03 ! chromosome condensation GO:0030261 48 25 1,000 6,417E-05 6,03E-03 ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 6,95E-05 6,289E-03 ! positive regulation of nuclear division GO:0051785 41 26 1,000 6,95E-05 6,064E-03 GO:0045840|positive regulation of mitosis, ! regulation of chromosome organization GO:0033044 49 27 1,000 7,504E-05 6,322E-03 ! fat cell differentiation GO:0045444 57 28 1,000 8,079E-05 6,579E-03 ! base-excision repair GO:0006284 41 28 1,000 8,079E-05 6,367E-03 ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 8,675E-05 6,623E-03 ! spindle organization GO:0007051 50 32 1,000 1,059E-04 7,839E-03 ! mitotic sister chromatid segregation GO:0000070 63 36 1,000 1,343E-04 9,653E-03 ! sister chromatid segregation GO:0000819 65 37 1,000 1,42E-04 9,911E-03 ! meiosis I GO:0007127 74 38 1,000 1,498E-04 0,01016779 ! nucleus organization GO:0006997 73 40 1,000 1,662E-04 0,01097039 ! cytokinesis GO:0000910 84 42 1,000 1,833E-04 0,01178432 ! response to calcium ion GO:0051592 94 49 1,000 2,499E-04 0,0156521 ! histone modification GO:0016570 104 52 1,000 2,815E-04 0,01719282 ! covalent chromatin modification GO:0016569 115 54 1,000 3,036E-04 0,01809153 ! response to UV GO:0009411 120 55 1,000 3,15E-04 0,01832207 ! regulation of DNA replication GO:0006275 105 56 1,000 3,266E-04 0,01855357 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 1,000 3,383E-04 0,01878595 ! positive regulation of organelle organization GO:0010638 108 58 1,000 3,503E-04 0,01901916 ! establishment of organelle localization GO:0051656 122 59 1,000 3,625E-04 0,01925312 ! regulation of mitosis GO:0007088 112 63 1,000 4,133E-04 0,02148448 GO:0051783|regulation of nuclear division, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 1,000 4,814E-04 0,02450318 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 1,000 4,957E-04 0,02471267 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 1,000 5,396E-04 0,02636407 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 1,000 5,396E-04 0,02584712 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 1,000 5,699E-04 0,0267731 ! organelle localization GO:0051640 155 74 1,000 5,699E-04 0,02626794 ! positive regulation of ligase activity GO:0051351 130 77 1,000 6,168E-04 0,02790562 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 1,000 6,491E-04 0,02883341 ! negative regulation of organelle organization GO:0010639 181 80 1,000 6,656E-04 0,02903648 ! meiosis GO:0007126 143 81 1,000 6,823E-04 0,02924105 GO:0051327|M phase of meiotic cell cycle, ! positive regulation of phosphorylation GO:0042327 149 81 1,000 6,823E-04 0,02873689 ! meiotic cell cycle GO:0051321 144 82 1,000 6,991E-04 0,02894794 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 7,162E-04 0,02916012 GO:0045937|positive regulation of phosphate metabolic process, ! response to metal ion GO:0010038 158 84 1,000 7,334E-04 0,0293734 ! regulation of ligase activity GO:0051340 147 84 1,000 7,334E-04 0,02889963 ! response to inorganic substance GO:0010035 173 90 1,000 8,412E-04 0,03262017 ! positive regulation of protein modification process GO:0031401 156 90 1,000 8,412E-04 0,03211048 ! response to unfolded protein GO:0006986 139 90 1,000 8,412E-04 0,03161647 ! regulation of cell cycle process GO:0010564 161 90 1,000 8,412E-04 0,03113743 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 1,000 8,978E-04 0,03273588 GO:0010498|proteasomal protein catabolic process, ! response to protein stimulus GO:0051789 158 96 1,000 9,562E-04 0,03435167 ! regulation of DNA metabolic process GO:0051052 188 97 1,000 9,76E-04 0,03455682 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 2,389E-03 0,08338483 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 2,389E-03 0,08221039 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 2,389E-03 0,08106858 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 2,389E-03 0,07995805 ! positive regulation of helicase activity GO:0051096 12 5 0,000 2,389E-03 0,07887754 ! neuron fate determination GO:0048664 7 5 0,000 2,389E-03 0,07782584 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 2,389E-03 0,07680182 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 2,389E-03 0,07580439 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 2,389E-03 0,07483254 ! polyol transport GO:0015791 12 5 0,000 2,389E-03 0,07388529 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 2,389E-03 0,07296172 ! response to superoxide GO:0000303 10 5 0,000 2,389E-03 0,07206096 ! negative regulation of bone resorption GO:0045779 10 5 0,000 2,389E-03 0,07118217 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 2,389E-03 0,07032455 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 2,389E-03 0,06948736 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 2,389E-03 0,06866986 ! female meiosis GO:0007143 10 5 0,000 2,389E-03 0,06787137 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 2,389E-03 0,06709124 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 2,389E-03 0,06632884 ! hypothalamus development GO:0021854 9 5 0,000 2,389E-03 0,06558357 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 2,389E-03 0,06485487 ! cobalt ion transport GO:0006824 11 5 0,000 2,389E-03 0,06414218 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 2,389E-03 0,06344498 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 2,389E-03 0,06276277 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 2,389E-03 0,06209508 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 2,389E-03 0,06144145 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 2,389E-03 0,06080144 ! embryonic camera-type eye development GO:0031076 12 5 0,000 2,389E-03 0,06017462 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 2,389E-03 0,05956059 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 2,389E-03 0,05895897 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 2,389E-03 0,05836938 ! transposition GO:0032196 9 5 0,000 2,389E-03 0,05779147 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 2,389E-03 0,05722488 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 2,389E-03 0,0566693 ! negative chemotaxis GO:0050919 16 5 0,000 2,389E-03 0,0561244 ! positive regulation of histone modification GO:0031058 6 5 0,000 2,389E-03 0,05558989 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 2,389E-03 0,05506545 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 2,389E-03 0,05455082 ! behavioral response to pain GO:0048266 10 5 0,000 2,389E-03 0,05404572 ! clathrin coat assembly GO:0048268 15 5 0,000 2,389E-03 0,05354989 ! Notch receptor processing GO:0007220 11 5 0,000 2,389E-03 0,05306307 ! regulation of dopamine uptake GO:0051584 9 5 0,000 2,389E-03 0,05258503 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 2,389E-03 0,05211552 ! micturition GO:0060073 9 5 0,000 2,389E-03 0,05165432 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 2,389E-03 0,05120121 ! copulation GO:0007620 9 5 0,000 2,389E-03 0,05075598 ! glial cell fate commitment GO:0021781 14 5 0,000 2,389E-03 0,05031843 ! protein maturation by protein folding GO:0022417 14 5 0,000 2,389E-03 0,04988836 ! bioluminescence GO:0008218 9 5 0,000 2,389E-03 0,04946558 ! spermidine metabolic process GO:0008216 7 5 0,000 2,389E-03 0,0490499 ! regulation of potassium ion transport GO:0043266 10 5 0,000 2,389E-03 0,04864115 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 2,389E-03 0,04823916 ! apoptotic cell clearance GO:0043277 23 5 0,000 2,389E-03 0,04784375 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 2,389E-03 0,04745478 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 2,389E-03 0,04707208 ! lipoprotein particle clearance GO:0034381 10 5 0,000 2,389E-03 0,0466955 ! grooming behavior GO:0007625 6 5 0,000 2,389E-03 0,0463249 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 2,389E-03 0,04596014 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 2,389E-03 0,04560108 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 2,389E-03 0,04524758 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 2,389E-03 0,04489952 ! response to protozoan GO:0001562 13 5 0,000 2,389E-03 0,04455678 ! positive regulation of glycolysis GO:0045821 13 5 0,000 2,389E-03 0,04421923 ! lymph vessel development GO:0001945 10 5 0,000 2,389E-03 0,04388675 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 2,389E-03 0,04355924 ! endochondral ossification GO:0001958 17 5 0,000 2,389E-03 0,04323658 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 2,389E-03 0,04291866 ! single strand break repair GO:0000012 8 5 0,000 2,389E-03 0,04260539 ! parathyroid gland development GO:0060017 14 5 0,000 2,389E-03 0,04229665 ! anagen GO:0042640 7 5 0,000 2,389E-03 0,04199236 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 2,389E-03 0,04169241 ! cytokine secretion GO:0050663 15 5 0,000 2,389E-03 0,04139672 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 2,389E-03 0,0411052 ! ceramide catabolic process GO:0046514 7 5 0,000 2,389E-03 0,04081775 ! skeletal myofibril assembly GO:0014866 12 5 0,000 2,389E-03 0,04053429 ! smooth muscle tissue development GO:0048745 32 5 0,000 2,389E-03 0,04025474 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 2,389E-03 0,03997903 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 2,389E-03 0,03970706 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 2,389E-03 0,03943877 ! cardiac muscle fiber development GO:0048739 12 5 0,000 2,389E-03 0,03917408 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 2,389E-03 0,03891292 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 2,389E-03 0,03865522 ! neutrophil mediated immunity GO:0002446 7 5 0,000 2,389E-03 0,03840091 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 2,389E-03 0,03814992 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 2,389E-03 0,03790219 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 2,389E-03 0,03765766 ! glycine biosynthetic process GO:0006545 7 5 0,000 2,389E-03 0,03741627 ! microvillus organization GO:0032528 8 5 0,000 2,389E-03 0,03717795 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 2,389E-03 0,03694265 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 2,389E-03 0,0367103 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 2,389E-03 0,03648086 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 2,389E-03 0,03625427 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 2,389E-03 0,03603048 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 2,389E-03 0,03580944 ! polyol catabolic process GO:0046174 9 5 0,000 2,389E-03 0,03559109 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 2,389E-03 0,03537538 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 2,389E-03 0,03516228 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 2,389E-03 0,03495172 ! muscle cell migration GO:0014812 8 5 0,000 2,389E-03 0,03474368 ! mitochondrial fission GO:0000266 8 5 0,000 2,389E-03 0,03453809 ! sister chromatid cohesion GO:0007062 15 5 0,000 2,389E-03 0,03433493 ! response to tumor necrosis factor GO:0034612 10 5 0,000 2,389E-03 0,03413414 ! mRNA transcription GO:0009299 10 5 0,000 2,389E-03 0,03393569 ! nerve growth factor processing GO:0032455 9 5 0,000 2,389E-03 0,03373953 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 2,389E-03 0,03354562 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 2,389E-03 0,03335393 ! anaerobic glycolysis GO:0019642 6 5 0,000 2,389E-03 0,03316442 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 2,389E-03 0,03297705 ! monocyte activation GO:0042117 10 5 0,000 2,389E-03 0,03279179 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 2,389E-03 0,03260859 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 2,389E-03 0,03242743 ! response to food GO:0032094 6 5 0,000 2,389E-03 0,03224828 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 2,389E-03 0,03207109 ! positive regulation of transporter activity GO:0032411 8 5 0,000 2,389E-03 0,03189584 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 2,389E-03 0,03172249 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 2,389E-03 0,03155102 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 2,389E-03 0,03138139 ! forebrain neuron development GO:0021884 13 5 0,000 2,389E-03 0,03121357 ! lipoprotein catabolic process GO:0042159 11 5 0,000 2,389E-03 0,03104754 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 2,389E-03 0,03088327 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 2,389E-03 0,03072073 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 2,389E-03 0,03055988 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 2,389E-03 0,03040072 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 2,389E-03 0,0302432 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 2,389E-03 0,03008731 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 2,389E-03 0,02993302 ! lipid glycosylation GO:0030259 7 5 0,000 2,389E-03 0,0297803 ! nucleobase transport GO:0015851 6 5 0,000 2,389E-03 0,02962913 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 2,389E-03 0,02947948 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 2,389E-03 0,02933135 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 2,389E-03 0,02918469 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 2,389E-03 0,02903949 ! basic amino acid transport GO:0015802 12 5 0,000 2,389E-03 0,02889573 ! cellular glucose homeostasis GO:0001678 6 5 0,000 2,389E-03 0,02875339 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 2,389E-03 0,02861244 ! actin nucleation GO:0045010 11 5 0,000 2,389E-03 0,02847287 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 2,389E-03 0,02833465 ! depurination GO:0045007 5 5 0,000 2,389E-03 0,02819777 ! depyrimidination GO:0045008 10 5 0,000 2,389E-03 0,0280622 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 2,389E-03 0,02792793 ! regulation of centrosome cycle GO:0046605 7 5 0,000 2,389E-03 0,02779494 ! G2/M transition checkpoint GO:0031576 8 5 0,000 2,389E-03 0,02766321 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 2,389E-03 0,02753273 ! zinc ion homeostasis GO:0055069 9 5 0,000 2,389E-03 0,02740346 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 2,389E-03 0,02727541 ! forebrain morphogenesis GO:0048853 13 5 0,000 2,389E-03 0,02714855 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 2,389E-03 0,02702286 ! activated T cell proliferation GO:0050798 16 5 0,000 2,389E-03 0,02689833 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 2,389E-03 0,02677494 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 2,389E-03 0,02665268 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 2,389E-03 0,02653154 ! positive regulation of organ growth GO:0046622 6 5 0,000 2,389E-03 0,02641148 ! gamma-delta T cell activation GO:0046629 6 5 0,000 2,389E-03 0,02629251 ! response to arsenic GO:0046685 11 5 0,000 2,389E-03 0,02617461 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 2,389E-03 0,02605776 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 2,389E-03 0,02594195 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 2,389E-03 0,02582716 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 2,389E-03 0,02571338 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 2,389E-03 0,02560061 ! response to mercury ion GO:0046689 8 5 0,000 2,389E-03 0,02548881 ! response to cadmium ion GO:0046686 7 5 0,000 2,389E-03 0,02537799 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 2,389E-03 0,02526813 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 2,389E-03 0,02515922 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 2,389E-03 0,02505124 ! bile acid biosynthetic process GO:0006699 7 5 0,000 2,389E-03 0,02494418 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 2,389E-03 0,02483803 ! ganglioside catabolic process GO:0006689 12 5 0,000 2,389E-03 0,02473279 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 2,389E-03 0,02462843 ! decidualization GO:0046697 11 5 0,000 2,389E-03 0,02452495 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 2,389E-03 0,02442233 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 2,389E-03 0,02432057 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 2,389E-03 0,02421966 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 2,389E-03 0,02411958 ! embryonic cleavage GO:0040016 6 5 0,000 2,389E-03 0,02402032 ! peroxisome fission GO:0016559 5 5 0,000 2,389E-03 0,02392188 ! histone demethylation GO:0016577 13 5 0,000 2,389E-03 0,02382424 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 2,389E-03 0,02372739 ! mitotic recombination GO:0006312 9 5 0,000 2,389E-03 0,02363133 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 2,389E-03 0,02353604 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 2,389E-03 0,02344152 ! metaphase plate congression GO:0051310 7 5 0,000 2,389E-03 0,02334775 ! regulation of sterol transport GO:0032371 7 5 0,000 2,389E-03 0,02325473 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 2,389E-03 0,02316245 ! enteric nervous system development GO:0048484 8 5 0,000 2,389E-03 0,0230709 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 2,389E-03 0,02298007 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 2,389E-03 0,02288995 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 2,389E-03 0,02280054 ! muscle cell proliferation GO:0033002 12 5 0,000 2,389E-03 0,02271182 ! skeletal muscle regeneration GO:0043403 8 5 0,000 2,389E-03 0,02262379 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 2,389E-03 0,02253644 ! B cell homeostasis GO:0001782 13 5 0,000 2,389E-03 0,02244976 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 2,389E-03 0,02236375 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 2,389E-03 0,02227839 ! metaphase GO:0051323 11 5 0,000 2,389E-03 0,02219368 ! melatonin biosynthetic process GO:0030187 7 5 0,000 2,389E-03 0,02210961 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 2,389E-03 0,02202618 ! cellular response to nutrient GO:0031670 8 5 0,000 2,389E-03 0,02194338 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 2,389E-03 0,02186119 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 2,389E-03 0,02177962 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 2,389E-03 0,02169865 ! regulation of hair follicle development GO:0051797 10 5 0,000 2,389E-03 0,02161829 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 2,389E-03 0,02153852 ! response to redox state GO:0051775 6 5 0,000 2,389E-03 0,02145933 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 2,389E-03 0,02138073 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 2,389E-03 0,02130269 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 2,389E-03 0,02122523 ! brown fat cell differentiation GO:0050873 7 5 0,000 2,389E-03 0,02114833 ! regulation of telomerase activity GO:0051972 7 5 0,000 2,389E-03 0,02107198 ! galactolipid metabolic process GO:0019374 7 5 0,000 2,389E-03 0,02099618 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 2,389E-03 0,02092092 ! porphyrin catabolic process GO:0006787 12 5 0,000 2,389E-03 0,02084621 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 2,389E-03 0,02077202 ! striatum development GO:0021756 14 5 0,000 2,389E-03 0,02069836 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 2,389E-03 0,02062522 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 2,389E-03 0,0205526 ! glial cell migration GO:0008347 10 5 0,000 2,389E-03 0,02048048 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 2,389E-03 0,02040887 ! neural plate morphogenesis GO:0001839 7 5 0,000 2,389E-03 0,02033776 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 2,389E-03 0,02026715 ! somatic stem cell maintenance GO:0035019 15 5 0,000 2,389E-03 0,02019702 ! T cell activation during immune response GO:0002286 9 5 0,000 2,389E-03 0,02012737 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 2,389E-03 0,02005821 ! negative regulation of lipase activity GO:0060192 8 5 0,000 2,389E-03 0,01998951 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 2,389E-03 0,01992129 ! neuroprotection GO:0043526 8 5 0,000 2,389E-03 0,01985353 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 2,389E-03 0,01978623 ! regulation of sensory perception GO:0051931 8 5 0,000 2,389E-03 0,01971939 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 2,389E-03 0,01965299 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 2,389E-03 0,01958704 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 2,389E-03 0,01952153 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 2,389E-03 0,01945646 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 2,389E-03 0,01939182 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 2,389E-03 0,01932761 ! sequestering of calcium ion GO:0051208 7 5 0,000 2,389E-03 0,01926382 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 2,389E-03 0,01920045 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 2,389E-03 0,0191375 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 2,389E-03 0,01907496 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 2,389E-03 0,01901283 ! spindle assembly GO:0051225 6 5 0,000 2,389E-03 0,0189511 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 2,389E-03 0,01888977 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 2,389E-03 0,01882883 ! protein palmitoylation GO:0018345 12 5 0,000 2,389E-03 0,01876829 ! drug metabolic process GO:0017144 7 5 0,000 2,389E-03 0,01870813 ! stem cell division GO:0017145 11 5 0,000 2,389E-03 0,01864836 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 2,389E-03 0,01858897 ! organ regeneration GO:0031100 7 5 0,000 2,389E-03 0,01852996 ! carnitine metabolic process GO:0009437 8 5 0,000 2,389E-03 0,01847132 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 2,389E-03 0,01841305 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 2,866E-03 0,02202122 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 2,866E-03 0,02195219 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 2,866E-03 0,02188359 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 2,866E-03 0,02181542 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 2,866E-03 0,02174767 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 2,866E-03 0,02168034 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 2,866E-03 0,02161342 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 2,866E-03 0,02154692 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 2,866E-03 0,02148083 ! response to oxygen radical GO:0000305 11 6 0,000 2,866E-03 0,02141514 ! positive regulation of axon extension GO:0045773 13 6 0,000 2,866E-03 0,02134985 ! myoblast cell fate commitment GO:0048625 18 6 0,000 2,866E-03 0,02128495 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 2,866E-03 0,02122045 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 2,866E-03 0,02115634 ! regulation of interferon-beta production GO:0032648 8 6 0,000 2,866E-03 0,02109262 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 2,866E-03 0,02102928 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 2,866E-03 0,02096632 ! forebrain regionalization GO:0021871 9 6 0,000 2,866E-03 0,02090373 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 2,866E-03 0,02084152 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 2,866E-03 0,02077967 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 2,866E-03 0,02071819 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 2,866E-03 0,02065708 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 2,866E-03 0,02059632 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 2,866E-03 0,02053592 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 2,866E-03 0,02047588 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 2,866E-03 0,02041618 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 2,866E-03 0,02035683 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 2,866E-03 0,02029782 ! malate metabolic process GO:0006108 13 6 0,000 2,866E-03 0,02023916 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 2,866E-03 0,02018083 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 2,866E-03 0,02012284 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 2,866E-03 0,02006518 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 2,866E-03 0,02000786 ! protein refolding GO:0042026 15 6 0,000 2,866E-03 0,01995085 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 2,866E-03 0,01989417 ! opsonization GO:0008228 8 6 0,000 2,866E-03 0,01983782 ! mating behavior GO:0007617 7 6 0,000 2,866E-03 0,01978178 ! erythrocyte maturation GO:0043249 8 6 0,000 2,866E-03 0,01972605 ! embryonic hemopoiesis GO:0035162 16 6 0,000 2,866E-03 0,01967064 ! protein amino acid dealkylation GO:0008214 15 6 0,000 2,866E-03 0,01961554 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 2,866E-03 0,01956075 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 2,866E-03 0,01950627 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 2,866E-03 0,01945208 ! response to interferon-gamma GO:0034341 16 6 0,000 2,866E-03 0,0193982 ! toxin metabolic process GO:0009404 11 6 0,000 2,866E-03 0,01934461 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 2,866E-03 0,01929132 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 2,866E-03 0,01923832 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 2,866E-03 0,01918561 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 2,866E-03 0,0191332 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 2,866E-03 0,01908106 ! cGMP-mediated signaling GO:0019934 14 6 0,000 2,866E-03 0,01902921 ! dorsal spinal cord development GO:0021516 10 6 0,000 2,866E-03 0,01897764 ! activation of MAPKKK activity GO:0000185 12 6 0,000 2,866E-03 0,01892635 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 2,866E-03 0,01887534 ! thymic T cell selection GO:0045061 16 6 0,000 2,866E-03 0,0188246 ! sphingoid catabolic process GO:0046521 8 6 0,000 2,866E-03 0,01877413 ! protein lipoylation GO:0009249 10 6 0,000 2,866E-03 0,01872393 ! transepithelial chloride transport GO:0030321 12 6 0,000 2,866E-03 0,018674 GO:0070633|transepithelial transport, ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 2,866E-03 0,01862433 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 2,866E-03 0,01857493 ! glutamate catabolic process GO:0006538 12 6 0,000 2,866E-03 0,01852579 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 2,866E-03 0,01847691 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 2,866E-03 0,01842829 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 2,866E-03 0,01837992 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 2,866E-03 0,0183318 ! hyperosmotic response GO:0006972 10 6 0,000 2,866E-03 0,01828394 ! L-serine biosynthetic process GO:0006564 7 6 0,000 2,866E-03 0,01823633 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 2,866E-03 0,01818896 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 2,866E-03 0,01814184 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 2,866E-03 0,01809496 ! urea metabolic process GO:0019627 7 6 0,000 2,866E-03 0,01804832 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 2,866E-03 0,01800193 ! neutrophil activation GO:0042119 7 6 0,000 2,866E-03 0,01795577 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 2,866E-03 0,01790984 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 2,866E-03 0,01786416 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 2,866E-03 0,0178187 ! paraxial mesoderm development GO:0048339 16 6 0,000 2,866E-03 0,01777348 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 2,866E-03 0,01772848 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 2,866E-03 0,01768371 ! neuron apoptosis GO:0051402 15 6 0,000 2,866E-03 0,01763917 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 2,866E-03 0,01759485 ! T cell mediated immunity GO:0002456 17 6 0,000 2,866E-03 0,01755075 ! negative regulation of platelet activation GO:0010544 9 6 0,000 2,866E-03 0,01750687 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 2,866E-03 0,01746322 ! carnitine transport GO:0015879 10 6 0,000 2,866E-03 0,01741977 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 2,866E-03 0,01737655 ! positive regulation of exocytosis GO:0045921 11 6 0,000 2,866E-03 0,01733354 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 2,866E-03 0,01729074 ! early endosome to late endosome transport GO:0045022 16 6 0,000 2,866E-03 0,01724815 ! 5S class rRNA transcription GO:0042791 13 6 0,000 2,866E-03 0,01720577 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 2,866E-03 0,0171636 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 2,866E-03 0,01712164 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 2,866E-03 0,01707988 ! sodium ion homeostasis GO:0055078 12 6 0,000 2,866E-03 0,01703832 ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 2,866E-03 0,01699696 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 2,866E-03 0,01695581 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 2,866E-03 0,01691485 ! response to UV-C GO:0010225 14 6 0,000 2,866E-03 0,01687409 ! astrocyte development GO:0014002 16 6 0,000 2,866E-03 0,01683353 ! protein targeting to lysosome GO:0006622 12 6 0,000 2,866E-03 0,01679316 ! purine base biosynthetic process GO:0009113 17 6 0,000 2,866E-03 0,01675299 ! interaction with symbiont GO:0051702 14 6 0,000 2,866E-03 0,01671301 ! regulation of dendrite development GO:0050773 16 6 0,000 2,866E-03 0,01667321 ! peptidyl-arginine modification GO:0018195 13 6 0,000 2,866E-03 0,01663361 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 2,866E-03 0,01659419 ! response to copper ion GO:0046688 10 6 0,000 2,866E-03 0,01655496 ! response to exogenous dsRNA GO:0043330 13 6 0,000 2,866E-03 0,01651592 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 2,866E-03 0,01647706 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 2,866E-03 0,01643838 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 2,866E-03 0,01639988 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 2,866E-03 0,01636156 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 2,866E-03 0,01632343 ! regulation of dopamine secretion GO:0014059 14 6 0,000 2,866E-03 0,01628546 ! nucleoside catabolic process GO:0009164 10 6 0,000 2,866E-03 0,01624768 ! hair follicle maturation GO:0048820 8 6 0,000 2,866E-03 0,01621007 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 2,866E-03 0,01617263 ! Schwann cell development GO:0014044 15 6 0,000 2,866E-03 0,01613537 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 2,866E-03 0,01609827 ! response to pheromone GO:0019236 6 6 0,000 2,866E-03 0,01606135 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 2,866E-03 0,0160246 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 2,866E-03 0,01598801 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 2,866E-03 0,01595159 ! base conversion or substitution editing GO:0016553 6 6 0,000 2,866E-03 0,01591534 ! subpallium development GO:0021544 15 6 0,000 2,866E-03 0,01587925 ! neural tube patterning GO:0021532 8 6 0,000 2,866E-03 0,01584332 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 2,866E-03 0,01580756 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 2,866E-03 0,01577196 ! maintenance of organ identity GO:0048496 9 6 0,000 2,866E-03 0,01573652 ! G2 phase GO:0051319 16 6 0,000 2,866E-03 0,01570123 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 2,866E-03 0,01566611 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 2,866E-03 0,01563114 ! oxygen homeostasis GO:0032364 10 6 0,000 2,866E-03 0,01559632 ! establishment of planar polarity GO:0001736 7 6 0,000 2,866E-03 0,01556167 ! regulation of mast cell activation GO:0033003 13 6 0,000 2,866E-03 0,01552716 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 2,866E-03 0,01549281 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 2,866E-03 0,01545861 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 2,866E-03 0,01542456 ! receptor internalization GO:0031623 11 6 0,000 2,866E-03 0,01539066 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 2,866E-03 0,01535691 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 2,866E-03 0,0153233 ! neutrophil homeostasis GO:0001780 11 6 0,000 2,866E-03 0,01528985 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 2,866E-03 0,01525653 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 2,866E-03 0,01522337 ! protein deubiquitination GO:0016579 16 6 0,000 2,866E-03 0,01519035 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 2,866E-03 0,01515747 ! protein destabilization GO:0031648 9 6 0,000 2,866E-03 0,01512473 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 2,866E-03 0,01509213 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 2,866E-03 0,01505968 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 2,866E-03 0,01502736 ! regulation of viral transcription GO:0046782 11 6 0,000 2,866E-03 0,01499518 ! progesterone metabolic process GO:0042448 12 6 0,000 2,866E-03 0,01496314 ! negative regulation of axon extension GO:0030517 24 6 0,000 2,866E-03 0,01493124 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 2,866E-03 0,01489947 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 2,866E-03 0,01486783 ! triglyceride catabolic process GO:0019433 10 6 0,000 2,866E-03 0,01483633 ! determination of adult lifespan GO:0008340 17 6 0,000 2,866E-03 0,01480497 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 2,866E-03 0,01477373 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 2,866E-03 0,01474263 ! neural plate development GO:0001840 9 6 0,000 2,866E-03 0,01471166 ! catecholamine transport GO:0051937 9 6 0,000 2,866E-03 0,01468082 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 2,866E-03 0,0146501 ! sensory cilium assembly GO:0035058 10 6 0,000 2,866E-03 0,01461952 ! organ or tissue specific immune response GO:0002251 8 6 0,000 2,866E-03 0,01458906 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 2,866E-03 0,01455873 ! maternal placenta development GO:0001893 12 6 0,000 2,866E-03 0,01452853 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 2,866E-03 0,01449845 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 2,866E-03 0,01446849 ! negative regulation of B cell activation GO:0050869 14 6 0,000 2,866E-03 0,01443866 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 2,866E-03 0,01440895 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 2,866E-03 0,01437936 ! positive regulation of coagulation GO:0050820 13 6 0,000 2,866E-03 0,0143499 ! cellular anion homeostasis GO:0030002 11 6 0,000 2,866E-03 0,01432055 GO:0055081|anion homeostasis, ! tRNA transcription GO:0009304 17 7 0,000 3,343E-03 0,01666946 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 3,343E-03 0,01663551 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 3,343E-03 0,0166017 ! behavioral response to cocaine GO:0048148 14 7 0,000 3,343E-03 0,01656802 ! regulation of helicase activity GO:0051095 16 7 0,000 3,343E-03 0,01653449 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 3,343E-03 0,01650108 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 3,343E-03 0,01646781 ! sleep GO:0030431 16 7 0,000 3,343E-03 0,01643468 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 3,343E-03 0,01640168 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 3,343E-03 0,01636881 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 3,343E-03 0,01633607 ! prostate gland development GO:0030850 14 7 0,000 3,343E-03 0,01630346 ! nucleotide-sugar transport GO:0015780 11 7 0,000 3,343E-03 0,01627099 ! synaptonemal complex assembly GO:0007130 10 7 0,000 3,343E-03 0,01623864 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 3,343E-03 0,01620642 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 3,343E-03 0,01617433 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 3,343E-03 0,01614236 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 3,343E-03 0,01611052 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 3,343E-03 0,01607881 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 3,343E-03 0,01604722 ! SMAD protein complex assembly GO:0007183 13 7 0,000 3,343E-03 0,01601576 ! glycolipid transport GO:0046836 11 7 0,000 3,343E-03 0,01598441 ! protein amino acid sulfation GO:0006477 10 7 0,000 3,343E-03 0,0159532 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 3,343E-03 0,0159221 ! neuron adhesion GO:0007158 14 7 0,000 3,343E-03 0,01589112 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 3,343E-03 0,01586026 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 3,343E-03 0,01582953 ! establishment of tissue polarity GO:0007164 8 7 0,000 3,343E-03 0,01579891 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 3,343E-03 0,01576841 ! mRNA stabilization GO:0048255 18 7 0,000 3,343E-03 0,01573803 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 3,343E-03 0,01570776 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 3,343E-03 0,01567761 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 3,343E-03 0,01564758 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 3,343E-03 0,01561766 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 3,343E-03 0,01558785 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 3,343E-03 0,01555816 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 3,343E-03 0,01552859 ! lipoprotein transport GO:0042953 14 7 0,000 3,343E-03 0,01549912 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 3,343E-03 0,01546977 ! rhythmic behavior GO:0007622 17 7 0,000 3,343E-03 0,01544052 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 3,343E-03 0,01541139 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 3,343E-03 0,01538237 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 3,343E-03 0,01535345 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 3,343E-03 0,01532465 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 3,343E-03 0,01529595 ! regulation of odontogenesis GO:0042481 14 7 0,000 3,343E-03 0,01526736 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 3,343E-03 0,01523887 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 3,343E-03 0,0152105 ! mechanosensory behavior GO:0007638 16 7 0,000 3,343E-03 0,01518222 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 3,343E-03 0,01515406 ! positive regulation of isotype switching GO:0045830 17 7 0,000 3,343E-03 0,01512599 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 3,343E-03 0,01509803 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 3,343E-03 0,01507018 ! protein-cofactor linkage GO:0018065 13 7 0,000 3,343E-03 0,01504242 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 3,343E-03 0,01501477 ! spinal cord patterning GO:0021511 14 7 0,000 3,343E-03 0,01498722 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 3,343E-03 0,01495977 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 3,343E-03 0,01493242 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 3,343E-03 0,01490518 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 3,343E-03 0,01487803 ! adrenal gland development GO:0030325 17 7 0,000 3,343E-03 0,01485097 ! cysteine metabolic process GO:0006534 13 7 0,000 3,343E-03 0,01482402 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 3,343E-03 0,01479717 ! ovulation GO:0030728 10 7 0,000 3,343E-03 0,01477041 ! adenohypophysis development GO:0021984 11 7 0,000 3,343E-03 0,01474375 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 3,343E-03 0,01471718 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 3,343E-03 0,01469071 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 3,343E-03 0,01466434 ! microtubule nucleation GO:0007020 21 7 0,000 3,343E-03 0,01463806 ! proline biosynthetic process GO:0006561 10 7 0,000 3,343E-03 0,01461187 ! tryptophan metabolic process GO:0006568 11 7 0,000 3,343E-03 0,01458578 ! thyroid hormone generation GO:0006590 13 7 0,000 3,343E-03 0,01455978 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 3,343E-03 0,01453387 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 3,343E-03 0,01450806 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 3,343E-03 0,01448233 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 3,343E-03 0,0144567 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 3,343E-03 0,01443116 ! galactose metabolic process GO:0006012 13 7 0,000 3,343E-03 0,01440571 ! vesicle fusion GO:0006906 20 7 0,000 3,343E-03 0,01438034 ! response to dietary excess GO:0002021 8 7 0,000 3,343E-03 0,01435507 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 3,343E-03 0,01432989 ! intracellular pH reduction GO:0051452 13 7 0,000 3,343E-03 0,01430479 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 3,343E-03 0,01427978 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 3,343E-03 0,01425486 ! organ growth GO:0035265 15 7 0,000 3,343E-03 0,01423003 ! nucleoside transport GO:0015858 11 7 0,000 3,343E-03 0,01420528 ! nucleoside salvage GO:0043174 11 7 0,000 3,343E-03 0,01418062 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 3,343E-03 0,01415604 ! male sex determination GO:0030238 15 7 0,000 3,343E-03 0,01413155 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 3,343E-03 0,01410714 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 3,343E-03 0,01408282 ! parturition GO:0007567 16 7 0,000 3,343E-03 0,01405858 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 3,343E-03 0,01403443 ! rRNA modification GO:0000154 14 7 0,000 3,343E-03 0,01401035 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 3,343E-03 0,01398636 ! spindle checkpoint GO:0031577 16 7 0,000 3,343E-03 0,01396245 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 3,343E-03 0,01393863 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 3,343E-03 0,01391488 ! monocyte differentiation GO:0030224 16 7 0,000 3,343E-03 0,01389122 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 3,343E-03 0,01386763 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 3,343E-03 0,01384413 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 3,343E-03 0,0138207 ! hyaluronan metabolic process GO:0030212 9 7 0,000 3,343E-03 0,01379736 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 3,343E-03 0,01377409 ! anterograde axon cargo transport GO:0008089 18 7 0,000 3,343E-03 0,0137509 ! fibrinolysis GO:0042730 11 7 0,000 3,343E-03 0,01372779 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 3,343E-03 0,01370476 ! skeletal muscle contraction GO:0003009 8 7 0,000 3,343E-03 0,0136818 ! eating behavior GO:0042755 8 7 0,000 3,343E-03 0,01365892 ! B cell lineage commitment GO:0002326 21 7 0,000 3,343E-03 0,01363612 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 3,343E-03 0,01361339 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 3,343E-03 0,01359074 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 3,343E-03 0,01356817 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 3,343E-03 0,01354566 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 3,343E-03 0,01352324 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 3,343E-03 0,01350089 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 3,343E-03 0,01347861 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 3,343E-03 0,0134564 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 3,343E-03 0,01343427 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 3,343E-03 0,01341221 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 3,343E-03 0,01339022 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 3,343E-03 0,01336831 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 3,343E-03 0,01334646 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 3,343E-03 0,01332469 ! histone ubiquitination GO:0016574 9 7 0,000 3,343E-03 0,01330299 ! regulation of meiosis GO:0040020 12 7 0,000 3,343E-03 0,01328136 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 3,343E-03 0,0132598 ! T cell lineage commitment GO:0002360 16 7 0,000 3,343E-03 0,01323831 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 3,343E-03 0,01321689 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 3,343E-03 0,01319553 ! membrane to membrane docking GO:0022614 14 7 0,000 3,343E-03 0,01317425 ! transcription termination GO:0006353 14 7 0,000 3,343E-03 0,01315304 ! coenzyme A metabolic process GO:0015936 12 7 0,000 3,343E-03 0,01313189 ! anaphase GO:0051322 18 7 0,000 3,343E-03 0,01311081 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 3,343E-03 0,0130898 ! axonal fasciculation GO:0007413 19 7 0,000 3,343E-03 0,01306886 ! negative regulation of nuclear division GO:0051784 15 7 0,000 3,343E-03 0,01304798 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 3,343E-03 0,01302717 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 3,343E-03 0,01300643 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 3,343E-03 0,01298575 ! diuresis GO:0030146 12 7 0,000 3,343E-03 0,01296514 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 3,343E-03 0,01294459 ! thiamin metabolic process GO:0006772 7 7 0,000 3,343E-03 0,01292411 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 3,343E-03 0,01290369 ! antibiotic transport GO:0042891 9 7 0,000 3,343E-03 0,01288334 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 3,343E-03 0,01286305 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 3,343E-03 0,01284282 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 3,343E-03 0,01282266 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 3,343E-03 0,01280256 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 3,343E-03 0,01278253 ! melanin biosynthetic process GO:0042438 10 7 0,000 3,343E-03 0,01276256 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 3,343E-03 0,01274265 ! dopamine biosynthetic process GO:0042416 18 7 0,000 3,343E-03 0,0127228 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 3,343E-03 0,01270301 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 3,343E-03 0,01268329 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 3,343E-03 0,01266362 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 3,343E-03 0,01264402 ! endosome to lysosome transport GO:0008333 12 7 0,000 3,343E-03 0,01262448 ! protein modification by small protein removal GO:0070646 19 7 0,000 3,343E-03 0,01260499 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 3,343E-03 0,01258557 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 3,343E-03 0,01256621 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 3,343E-03 0,01254691 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 3,343E-03 0,01252766 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 3,343E-03 0,01250848 ! muscle adaptation GO:0043500 13 7 0,000 3,343E-03 0,01248935 ! embryonic heart tube development GO:0035050 14 7 0,000 3,343E-03 0,01247028 ! retina homeostasis GO:0001895 12 7 0,000 3,343E-03 0,01245127 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 3,343E-03 0,01243232 ! protein amino acid prenylation GO:0018346 19 7 0,000 3,343E-03 0,01241343 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 3,343E-03 0,01239459 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 3,343E-03 0,01237581 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 3,82E-03 0,01411921 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 3,82E-03 0,01409788 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 3,82E-03 0,01407662 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 3,82E-03 0,01405542 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 3,82E-03 0,01403428 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 3,82E-03 0,01401321 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 3,82E-03 0,0139922 ! male meiosis GO:0007140 9 8 0,000 3,82E-03 0,01397125 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 3,82E-03 0,01395037 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 3,82E-03 0,01392955 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 3,82E-03 0,01390879 ! meiotic prophase I GO:0007128 14 8 0,000 3,82E-03 0,01388809 ! response to zinc ion GO:0010043 12 8 0,000 3,82E-03 0,01386746 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 3,82E-03 0,01384688 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 3,82E-03 0,01382637 ! oligopeptide transport GO:0006857 16 8 0,000 3,82E-03 0,01380591 ! actin-myosin filament sliding GO:0033275 13 8 0,000 3,82E-03 0,01378552 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 3,82E-03 0,01376519 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 3,82E-03 0,01374492 ! signal peptide processing GO:0006465 12 8 0,000 3,82E-03 0,0137247 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 3,82E-03 0,01370455 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 3,82E-03 0,01368445 ! macrophage chemotaxis GO:0048246 12 8 0,000 3,82E-03 0,01366442 ! succinate metabolic process GO:0006105 17 8 0,000 3,82E-03 0,01364444 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 3,82E-03 0,01362452 ! membrane hyperpolarization GO:0060081 11 8 0,000 3,82E-03 0,01360466 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 3,82E-03 0,01358486 ! estrogen metabolic process GO:0008210 17 8 0,000 3,82E-03 0,01356511 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 3,82E-03 0,01354543 ! T-helper 1 type immune response GO:0042088 12 8 0,000 3,82E-03 0,01352579 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 3,82E-03 0,01350622 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 3,82E-03 0,0134867 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 3,82E-03 0,01346724 ! reflex GO:0060004 17 8 0,000 3,82E-03 0,01344784 ! endothelial cell differentiation GO:0045446 17 8 0,000 3,82E-03 0,01342849 ! glycerolipid catabolic process GO:0046503 14 8 0,000 3,82E-03 0,01340919 ! hemoglobin metabolic process GO:0020027 14 8 0,000 3,82E-03 0,01338995 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 3,82E-03 0,01337077 ! pigment granule organization GO:0048753 17 8 0,000 3,82E-03 0,01335164 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 3,82E-03 0,01333257 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 3,82E-03 0,01331355 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 3,82E-03 0,01329458 ! astrocyte differentiation GO:0048708 19 8 0,000 3,82E-03 0,01327567 ! histidine catabolic process GO:0006548 10 8 0,000 3,82E-03 0,01325682 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 3,82E-03 0,01323801 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 3,82E-03 0,01321926 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 3,82E-03 0,01320056 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 3,82E-03 0,01318192 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 3,82E-03 0,01316333 ! regulation of pigmentation during development GO:0048070 25 8 0,000 3,82E-03 0,01314479 ! melanin metabolic process GO:0006582 17 8 0,000 3,82E-03 0,0131263 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 3,82E-03 0,01310786 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 3,82E-03 0,01308948 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 3,82E-03 0,01307115 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 3,82E-03 0,01305286 ! macrophage activation GO:0042116 13 8 0,000 3,82E-03 0,01303463 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 3,82E-03 0,01301645 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 3,82E-03 0,01299833 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 3,82E-03 0,01298025 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 3,82E-03 0,01296222 ! purine salvage GO:0043101 12 8 0,000 3,82E-03 0,01294424 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 3,82E-03 0,01292631 ! regulation of vascular permeability GO:0043114 12 8 0,000 3,82E-03 0,01290843 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 3,82E-03 0,0128906 ! osteoblast development GO:0002076 17 8 0,000 3,82E-03 0,01287282 ! positive regulation of vasodilation GO:0045909 14 8 0,000 3,82E-03 0,01285509 ! negative regulation of translational initiation GO:0045947 12 8 0,000 3,82E-03 0,01283741 ! Schwann cell differentiation GO:0014037 21 8 0,000 3,82E-03 0,01281978 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 3,82E-03 0,01280219 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 3,82E-03 0,01278465 ! response to UV-B GO:0010224 17 8 0,000 3,82E-03 0,01276717 ! protein targeting to vacuole GO:0006623 14 8 0,000 3,82E-03 0,01274972 ! protein retention in ER lumen GO:0006621 14 8 0,000 3,82E-03 0,01273233 ! intermediate filament organization GO:0045109 12 8 0,000 3,82E-03 0,01271498 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 3,82E-03 0,01269768 ! cellular extravasation GO:0045123 13 8 0,000 3,82E-03 0,01268043 ! cardiac muscle cell development GO:0055013 14 8 0,000 3,82E-03 0,01266323 ! response to antibiotic GO:0046677 11 8 0,000 3,82E-03 0,01264607 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 3,82E-03 0,01262896 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 3,82E-03 0,01261189 ! response to tropane GO:0014073 15 8 0,000 3,82E-03 0,01259487 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 3,82E-03 0,01257789 ! melanosome transport GO:0032402 13 8 0,000 3,82E-03 0,01256097 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 0,000 3,82E-03 0,01254408 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 3,82E-03 0,01252725 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 3,82E-03 0,01251045 ! mast cell activation GO:0045576 14 8 0,000 3,82E-03 0,01249371 ! multicellular organismal aging GO:0010259 20 8 0,000 3,82E-03 0,012477 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 3,82E-03 0,01246034 ! gas homeostasis GO:0033483 14 8 0,000 3,82E-03 0,01244373 ! dendrite morphogenesis GO:0048813 14 8 0,000 3,82E-03 0,01242716 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 3,82E-03 0,01241064 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 3,82E-03 0,01239415 ! nucleosome disassembly GO:0006337 14 8 0,000 3,82E-03 0,01237772 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 3,82E-03 0,01236132 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 3,82E-03 0,01234497 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 3,82E-03 0,01232866 ! establishment of chromosome localization GO:0051303 14 8 0,000 3,82E-03 0,0123124 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 3,82E-03 0,01229618 ! intracellular lipid transport GO:0032365 16 8 0,000 3,82E-03 0,01228 ! response to tumor cell GO:0002347 16 8 0,000 3,82E-03 0,01226386 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 3,82E-03 0,01224777 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 3,82E-03 0,01223171 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 3,82E-03 0,0122157 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 3,82E-03 0,01219974 ! positive regulation of epidermis development GO:0045684 13 8 0,000 3,82E-03 0,01218381 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 3,82E-03 0,01216792 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 3,82E-03 0,01215208 ! hormone catabolic process GO:0042447 17 8 0,000 3,82E-03 0,01213628 ! glycolipid catabolic process GO:0019377 16 8 0,000 3,82E-03 0,01212052 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 3,82E-03 0,0121048 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 3,82E-03 0,01208912 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 3,82E-03 0,01207348 ! positive regulation of glucose import GO:0046326 8 8 0,000 3,82E-03 0,01205788 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 3,82E-03 0,01204232 ! adult feeding behavior GO:0008343 10 8 0,000 3,82E-03 0,0120268 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 3,82E-03 0,01201132 ! ATP catabolic process GO:0006200 11 8 0,000 3,82E-03 0,01199588 ! blastocyst growth GO:0001832 19 8 0,000 3,82E-03 0,01198049 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 3,82E-03 0,01196513 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 3,82E-03 0,01194981 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 3,82E-03 0,01193452 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 3,82E-03 0,01191928 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 3,82E-03 0,01190408 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 3,82E-03 0,01188891 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 3,82E-03 0,01187379 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 3,82E-03 0,0118587 ! amino sugar catabolic process GO:0046348 11 8 0,000 3,82E-03 0,01184365 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 3,82E-03 0,01182864 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 3,82E-03 0,01181367 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 3,82E-03 0,01179873 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 3,82E-03 0,01178384 ! behavioral response to nicotine GO:0035095 12 8 0,000 3,82E-03 0,01176898 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 3,82E-03 0,01175415 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 3,82E-03 0,01173937 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 3,82E-03 0,01172462 ! NAD biosynthetic process GO:0009435 17 8 0,000 3,82E-03 0,01170991 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 3,82E-03 0,01169524 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 3,82E-03 0,0116806 ! axon extension GO:0048675 16 9 0,000 4,297E-03 0,01312129 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 4,297E-03 0,01310491 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 4,297E-03 0,01308857 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 4,297E-03 0,01307227 ! pentose-phosphate shunt GO:0006098 16 9 0,000 4,297E-03 0,01305601 GO:0006740|NADPH regeneration, ! cell proliferation in forebrain GO:0021846 18 9 0,000 4,297E-03 0,0130398 ! neutral lipid catabolic process GO:0046461 14 9 0,000 4,297E-03 0,01302362 ! reproductive behavior GO:0019098 22 9 0,000 4,297E-03 0,01300748 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 4,297E-03 0,01299138 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 4,297E-03 0,01297532 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 4,297E-03 0,0129593 ! UTP metabolic process GO:0046051 10 9 0,000 4,297E-03 0,01294332 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 4,297E-03 0,01292738 ! induction of positive chemotaxis GO:0050930 17 9 0,000 4,297E-03 0,01291148 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 4,297E-03 0,01289562 ! artery development GO:0060840 25 9 0,000 4,297E-03 0,0128798 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 4,297E-03 0,01286401 ! regulation of glycolysis GO:0006110 20 9 0,000 4,297E-03 0,01284827 ! cerebral cortex cell migration GO:0021795 18 9 0,000 4,297E-03 0,01283256 ! equilibrioception GO:0050957 20 9 0,000 4,297E-03 0,01281689 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 4,297E-03 0,01280126 ! chemosensory behavior GO:0007635 21 9 0,000 4,297E-03 0,01278567 ! microtubule bundle formation GO:0001578 22 9 0,000 4,297E-03 0,01277012 ! middle ear morphogenesis GO:0042474 14 9 0,000 4,297E-03 0,0127546 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 4,297E-03 0,01273912 ! leukocyte degranulation GO:0043299 16 9 0,000 4,297E-03 0,01272368 ! ganglioside metabolic process GO:0001573 22 9 0,000 4,297E-03 0,01270828 ! negative regulation of endocytosis GO:0045806 12 9 0,000 4,297E-03 0,01269291 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 4,297E-03 0,01267758 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 4,297E-03 0,01266229 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 4,297E-03 0,01264703 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 4,297E-03 0,01263181 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 4,297E-03 0,01261663 ! protein targeting to ER GO:0045047 25 9 0,000 4,297E-03 0,01260148 ! ceramide biosynthetic process GO:0046513 20 9 0,000 4,297E-03 0,01258637 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 4,297E-03 0,0125713 ! T cell selection GO:0045058 27 9 0,000 4,297E-03 0,01255626 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 0,000 4,297E-03 0,01254126 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 4,297E-03 0,0125263 ! glycine catabolic process GO:0006546 15 9 0,000 4,297E-03 0,01251137 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 4,297E-03 0,01249647 ! endosome organization GO:0007032 20 9 0,000 4,297E-03 0,01248161 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 4,297E-03 0,01246679 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 4,297E-03 0,012452 ! regulation of type I interferon production GO:0032479 12 9 0,000 4,297E-03 0,01243725 ! mannose metabolic process GO:0006013 13 9 0,000 4,297E-03 0,01242253 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 4,297E-03 0,01240784 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 4,297E-03 0,01239319 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 4,297E-03 0,01237858 ! Rac protein signal transduction GO:0016601 20 9 0,000 4,297E-03 0,012364 ! receptor clustering GO:0043113 20 9 0,000 4,297E-03 0,01234945 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 4,297E-03 0,01233494 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 4,297E-03 0,01232046 ! retinol metabolic process GO:0042572 20 9 0,000 4,297E-03 0,01230602 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 4,297E-03 0,01229161 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 4,297E-03 0,01227723 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 4,297E-03 0,01226289 ! macrophage differentiation GO:0030225 15 9 0,000 4,297E-03 0,01224858 ! oligodendrocyte development GO:0014003 11 9 0,000 4,297E-03 0,01223431 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 4,297E-03 0,01222006 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 4,297E-03 0,01220585 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 4,297E-03 0,01219168 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 4,297E-03 0,01217754 ! response to amine stimulus GO:0014075 13 9 0,000 4,297E-03 0,01216342 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 4,297E-03 0,01214935 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 4,297E-03 0,0121353 ! erythrocyte development GO:0048821 17 9 0,000 4,297E-03 0,01212129 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 4,297E-03 0,01210731 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 4,297E-03 0,01209336 ! renal water homeostasis GO:0003091 15 9 0,000 4,297E-03 0,01207944 ! postreplication repair GO:0006301 25 9 0,000 4,297E-03 0,01206556 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 4,297E-03 0,01205171 ! icosanoid secretion GO:0032309 15 9 0,000 4,297E-03 0,01203788 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 4,297E-03 0,0120241 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 4,297E-03 0,01201034 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 4,297E-03 0,01199661 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 4,297E-03 0,01198292 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 4,297E-03 0,01196925 ! sterol catabolic process GO:0016127 14 9 0,000 4,297E-03 0,01195562 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 4,297E-03 0,01194202 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 4,297E-03 0,01192845 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 4,297E-03 0,01191491 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 4,297E-03 0,0119014 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 4,297E-03 0,01188792 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 4,297E-03 0,01187447 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 4,297E-03 0,01186106 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 4,297E-03 0,01184767 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 4,297E-03 0,01183431 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 4,297E-03 0,01182099 ! regulation of synaptogenesis GO:0051963 15 9 0,000 4,297E-03 0,01180769 ! purine base metabolic process GO:0006144 25 9 0,000 4,297E-03 0,01179442 ! pigment granule transport GO:0051904 17 9 0,000 4,297E-03 0,01178118 ! regulation of telomere maintenance GO:0032204 17 9 0,000 4,297E-03 0,01176798 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 4,297E-03 0,0117548 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 4,297E-03 0,01174165 ! regulation of muscle adaptation GO:0043502 14 9 0,000 4,297E-03 0,01172853 ! regulation of amino acid transport GO:0051955 12 9 0,000 4,297E-03 0,01171544 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 4,297E-03 0,01170238 ! mitochondrion localization GO:0051646 18 9 0,000 4,297E-03 0,01168935 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 4,773E-03 0,0129708 ! regulation of developmental growth GO:0048638 16 10 0,000 4,773E-03 0,01295639 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 0,000 4,773E-03 0,01294201 ! autophagic vacuole formation GO:0000045 17 10 0,000 4,773E-03 0,01292766 ! negative regulation of blood pressure GO:0045776 26 10 0,000 4,773E-03 0,01291334 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 4,773E-03 0,01289906 ! associative learning GO:0008306 21 10 0,000 4,773E-03 0,01288481 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 4,773E-03 0,01287058 ! regulation of phosphatase activity GO:0010921 28 10 0,000 4,773E-03 0,01285639 ! phosphate transport GO:0006817 24 10 0,000 4,773E-03 0,01284223 ! cell volume homeostasis GO:0006884 17 10 0,000 4,773E-03 0,01282811 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 4,773E-03 0,01281401 ! CTP metabolic process GO:0046036 11 10 0,000 4,773E-03 0,01279994 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 4,773E-03 0,01278591 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 4,773E-03 0,0127719 ! GTP metabolic process GO:0046039 11 10 0,000 4,773E-03 0,01275793 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 4,773E-03 0,01274399 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 4,773E-03 0,01273007 ! social behavior GO:0035176 29 10 0,000 4,773E-03 0,01271619 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 4,773E-03 0,01270234 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 4,773E-03 0,01268852 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 4,773E-03 0,01267473 ! androgen metabolic process GO:0008209 17 10 0,000 4,773E-03 0,01266096 ! phospholipid efflux GO:0033700 19 10 0,000 4,773E-03 0,01264723 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 4,773E-03 0,01263353 ! bile acid and bile salt transport GO:0015721 15 10 0,000 4,773E-03 0,01261986 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 4,773E-03 0,01260621 ! positive regulation of heart contraction GO:0045823 17 10 0,000 4,773E-03 0,0125926 ! lung alveolus development GO:0048286 26 10 0,000 4,773E-03 0,01257902 ! pathogenesis GO:0009405 17 10 0,000 4,773E-03 0,01256546 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 4,773E-03 0,01255194 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 4,773E-03 0,01253844 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 4,773E-03 0,01252497 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 4,773E-03 0,01251153 ! endoderm development GO:0007492 18 10 0,000 4,773E-03 0,01249812 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 4,773E-03 0,01248474 ! arginine catabolic process GO:0006527 17 10 0,000 4,773E-03 0,01247139 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 4,773E-03 0,01245806 ! proline metabolic process GO:0006560 13 10 0,000 4,773E-03 0,01244477 ! glucan biosynthetic process GO:0009250 14 10 0,000 4,773E-03 0,0124315 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 4,773E-03 0,01241826 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 4,773E-03 0,01240505 ! V(D)J recombination GO:0033151 34 10 0,000 4,773E-03 0,01239187 ! reverse cholesterol transport GO:0043691 19 10 0,000 4,773E-03 0,01237871 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 4,773E-03 0,01236559 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 4,773E-03 0,01235249 ! B cell proliferation GO:0042100 19 10 0,000 4,773E-03 0,01233942 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 4,773E-03 0,01232637 ! regulation of sodium ion transport GO:0002028 26 10 0,000 4,773E-03 0,01231336 ! multicellular organism growth GO:0035264 19 10 0,000 4,773E-03 0,01230037 ! phagocytosis, engulfment GO:0006911 33 10 0,000 4,773E-03 0,01228741 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 4,773E-03 0,01227447 ! ruffle organization GO:0031529 17 10 0,000 4,773E-03 0,01226157 ! epithelial cell development GO:0002064 21 10 0,000 4,773E-03 0,01224869 ! lens development in camera-type eye GO:0002088 17 10 0,000 4,773E-03 0,01223583 ! retinoic acid metabolic process GO:0042573 14 10 0,000 4,773E-03 0,01222301 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 4,773E-03 0,01221021 ! positive regulation of translational initiation GO:0045948 12 10 0,000 4,773E-03 0,01219744 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 4,773E-03 0,01218469 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 4,773E-03 0,01217197 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 4,773E-03 0,01215928 ! motor axon guidance GO:0008045 22 10 0,000 4,773E-03 0,01214661 ! copper ion homeostasis GO:0055070 13 10 0,000 4,773E-03 0,01213397 ! regulation of bone resorption GO:0045124 25 10 0,000 4,773E-03 0,01212136 ! protein heterooligomerization GO:0051291 17 10 0,000 4,773E-03 0,01210877 ! regulation of gliogenesis GO:0014013 23 10 0,000 4,773E-03 0,01209621 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 4,773E-03 0,01208368 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 4,773E-03 0,01207117 ! segment specification GO:0007379 15 10 0,000 4,773E-03 0,01205869 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 4,773E-03 0,01204623 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 4,773E-03 0,0120338 ! blastoderm segmentation GO:0007350 19 10 0,000 4,773E-03 0,01202139 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 4,773E-03 0,01200901 ! response to dsRNA GO:0043331 23 10 0,000 4,773E-03 0,01199665 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 4,773E-03 0,01198433 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 4,773E-03 0,01197202 ! melanosome localization GO:0032400 16 10 0,000 4,773E-03 0,01195974 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 4,773E-03 0,01194749 ! regulation of B cell differentiation GO:0045577 24 10 0,000 4,773E-03 0,01193526 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 4,773E-03 0,01192306 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 4,773E-03 0,01191088 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 4,773E-03 0,01189872 ! induction of an organ GO:0001759 17 10 0,000 4,773E-03 0,01188659 ! leukocyte activation during immune response GO:0002366 15 10 0,000 4,773E-03 0,01187449 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 4,773E-03 0,01186241 ! protein sumoylation GO:0016925 17 10 0,000 4,773E-03 0,01185035 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 4,773E-03 0,01183832 ! hindbrain morphogenesis GO:0021575 19 10 0,000 4,773E-03 0,01182632 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 4,773E-03 0,01181433 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 4,773E-03 0,01180238 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 4,773E-03 0,01179044 ! salivary gland development GO:0007431 28 10 0,000 4,773E-03 0,01177853 ! ubiquinone metabolic process GO:0006743 17 10 0,000 4,773E-03 0,01176665 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 4,773E-03 0,01175479 ! midbrain development GO:0030901 14 10 0,000 4,773E-03 0,01174295 ! musculoskeletal movement GO:0050881 16 10 0,000 4,773E-03 0,01173114 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 4,773E-03 0,01171935 ! methionine biosynthetic process GO:0009086 21 10 0,000 4,773E-03 0,01170758 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 4,773E-03 0,01169584 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 4,773E-03 0,01168412 ! quaternary ammonium group transport GO:0015697 22 10 0,000 4,773E-03 0,01167242 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 4,773E-03 0,01166075 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 4,773E-03 0,0116491 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 4,773E-03 0,01163747 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 4,773E-03 0,01162587 ! establishment of pigment granule localization GO:0051905 18 10 0,000 4,773E-03 0,01161429 ! blastocyst formation GO:0001825 18 10 0,000 4,773E-03 0,01160273 ! regulation of fibrinolysis GO:0051917 20 10 0,000 4,773E-03 0,0115912 ! cerebellar cortex development GO:0021695 16 10 0,000 4,773E-03 0,01157969 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 4,773E-03 0,0115682 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 4,773E-03 0,01155674 ! response to nicotine GO:0035094 20 10 0,000 4,773E-03 0,0115453 ! negative regulation of immune effector process GO:0002698 23 10 0,000 4,773E-03 0,01153388 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 4,773E-03 0,01152248 ! negative regulation of muscle development GO:0048635 27 11 0,000 5,249E-03 0,01265937 ! respiratory burst GO:0045730 17 11 0,000 5,249E-03 0,01264688 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 5,249E-03 0,01263442 ! neuron fate specification GO:0048665 18 11 0,000 5,249E-03 0,01262199 ! telencephalon cell migration GO:0022029 23 11 0,000 5,249E-03 0,01260958 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 5,249E-03 0,01259719 ! thyroid gland development GO:0030878 26 11 0,000 5,249E-03 0,01258483 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 5,249E-03 0,01257249 ! synapsis GO:0007129 14 11 0,000 5,249E-03 0,01256017 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 5,249E-03 0,01254788 ! Golgi vesicle budding GO:0048194 26 11 0,000 5,249E-03 0,01253562 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 5,249E-03 0,01252338 ! response to pain GO:0048265 27 11 0,000 5,249E-03 0,01251116 ! detection of mechanical stimulus GO:0050982 22 11 0,000 5,249E-03 0,01249896 ! keratinocyte proliferation GO:0043616 19 11 0,000 5,249E-03 0,01248679 ! blood vessel remodeling GO:0001974 30 11 0,000 5,249E-03 0,01247465 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 5,249E-03 0,01246252 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 5,249E-03 0,01245043 ! bone resorption GO:0045453 16 11 0,000 5,249E-03 0,01243835 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 5,249E-03 0,0124263 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 5,249E-03 0,01241427 ! negative regulation of proteolysis GO:0045861 25 11 0,000 5,249E-03 0,01240226 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 5,249E-03 0,01239028 ! melanocyte differentiation GO:0030318 20 11 0,000 5,249E-03 0,01237832 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 5,249E-03 0,01236638 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 5,249E-03 0,01235447 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 5,249E-03 0,01234258 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 5,249E-03 0,01233071 ! regulation of intracellular pH GO:0051453 21 11 0,000 5,249E-03 0,01231886 ! substrate-bound cell migration GO:0006929 14 11 0,000 5,249E-03 0,01230704 ! UV protection GO:0009650 20 11 0,000 5,249E-03 0,01229524 ! adult heart development GO:0007512 16 11 0,000 5,249E-03 0,01228347 ! chondrocyte differentiation GO:0002062 27 11 0,000 5,249E-03 0,01227171 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 5,249E-03 0,01225998 ! macroautophagy GO:0016236 19 11 0,000 5,249E-03 0,01224827 ! temperature homeostasis GO:0001659 18 11 0,000 5,249E-03 0,01223658 ! behavioral fear response GO:0001662 27 11 0,000 5,249E-03 0,01222492 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 5,249E-03 0,01221327 ! negative regulation of ossification GO:0030279 27 11 0,000 5,249E-03 0,01220165 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 5,249E-03 0,01219005 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 5,249E-03 0,01217848 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 5,249E-03 0,01216692 ! alpha-beta T cell activation GO:0046631 26 11 0,000 5,249E-03 0,01215539 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 5,249E-03 0,01214388 ! regulation of organ growth GO:0046620 14 11 0,000 5,249E-03 0,01213239 ! pigment granule localization GO:0051875 20 11 0,000 5,249E-03 0,01212092 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 5,249E-03 0,01210948 ! vasoconstriction GO:0042310 20 11 0,000 5,249E-03 0,01209805 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 5,249E-03 0,01208665 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 5,249E-03 0,01207527 ! embryonic axis specification GO:0000578 19 11 0,000 5,249E-03 0,01206391 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 5,249E-03 0,01205257 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 5,249E-03 0,01204126 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 5,249E-03 0,01202996 ! nitric oxide metabolic process GO:0046209 17 11 0,000 5,249E-03 0,01201869 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 5,249E-03 0,01200743 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 5,249E-03 0,0119962 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 5,249E-03 0,01198499 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 5,249E-03 0,0119738 ! prophase GO:0051324 17 11 0,000 5,249E-03 0,01196263 ! neuroblast proliferation GO:0007405 25 11 0,000 5,249E-03 0,01195148 ! nucleosome positioning GO:0016584 15 11 0,000 5,249E-03 0,01194035 ! regulation of isotype switching GO:0045191 24 11 0,000 5,249E-03 0,01192924 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 5,249E-03 0,01191816 ! negative regulation of neurological system process GO:0031645 21 11 0,000 5,249E-03 0,01190709 ! apical protein localization GO:0045176 18 11 0,000 5,249E-03 0,01189605 ! acid secretion GO:0046717 20 11 0,000 5,249E-03 0,01188502 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 5,249E-03 0,01187402 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 5,249E-03 0,01186303 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 5,249E-03 0,01185207 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 5,249E-03 0,01184112 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 5,249E-03 0,0118302 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 5,249E-03 0,0118193 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 5,249E-03 0,01180841 ! cholesterol efflux GO:0033344 21 11 0,000 5,249E-03 0,01179755 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 5,249E-03 0,01178671 ! oocyte development GO:0048599 20 11 0,000 5,249E-03 0,01177588 ! negative regulation of glucose import GO:0046325 18 11 0,000 5,249E-03 0,01176508 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 5,249E-03 0,0117543 ! embryonic gut development GO:0048566 19 11 0,000 5,249E-03 0,01174353 ! regulation of organic acid transport GO:0032890 19 11 0,000 5,249E-03 0,01173279 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 5,249E-03 0,01172206 ! activation of innate immune response GO:0002218 16 11 0,000 5,249E-03 0,01171136 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 5,249E-03 0,01170067 ! cardiac cell differentiation GO:0035051 36 11 0,000 5,249E-03 0,01169001 ! lysogeny GO:0030069 22 11 0,000 5,249E-03 0,01167936 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 5,249E-03 0,01166873 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 5,249E-03 0,01165813 ! sequestering of metal ion GO:0051238 15 11 0,000 5,249E-03 0,01164754 ! regulation of embryonic development GO:0045995 35 11 0,000 5,249E-03 0,01163697 ! nucleus localization GO:0051647 22 11 0,000 5,249E-03 0,01162642 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 5,725E-03 0,01266902 ! positive regulation of blood pressure GO:0045777 18 12 0,000 5,725E-03 0,01265756 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 5,725E-03 0,01264612 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 5,725E-03 0,01263469 ! virus-host interaction GO:0019048 30 12 0,000 5,725E-03 0,01262329 ! regulation of B cell proliferation GO:0030888 22 12 0,000 5,725E-03 0,01261191 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 5,725E-03 0,01260054 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 5,725E-03 0,0125892 ! protein complex disassembly GO:0043241 28 12 0,000 5,725E-03 0,01257788 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 5,725E-03 0,01256658 ! regulation of cell projection assembly GO:0060491 33 12 0,000 5,725E-03 0,0125553 ! hippocampus development GO:0021766 29 12 0,000 5,725E-03 0,01254404 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 5,725E-03 0,0125328 ! cytokine biosynthetic process GO:0042089 23 12 0,000 5,725E-03 0,01252158 ! T cell proliferation GO:0042098 32 12 0,000 5,725E-03 0,01251038 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 5,725E-03 0,0124992 ! regulation of exit from mitosis GO:0007096 19 12 0,000 5,725E-03 0,01248804 ! ventral spinal cord development GO:0021517 25 12 0,000 5,725E-03 0,0124769 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 5,725E-03 0,01246578 ! drug transport GO:0015893 16 12 0,000 5,725E-03 0,01245468 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 5,725E-03 0,0124436 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 5,725E-03 0,01243254 ! tyrosine metabolic process GO:0006570 19 12 0,000 5,725E-03 0,01242149 ! polyamine metabolic process GO:0006595 18 12 0,000 5,725E-03 0,01241047 ! focal adhesion formation GO:0048041 37 12 0,000 5,725E-03 0,01239947 ! mitotic spindle organization GO:0007052 23 12 0,000 5,725E-03 0,01238849 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 5,725E-03 0,01237753 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 5,725E-03 0,01236658 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 5,725E-03 0,01235566 ! lipid digestion GO:0044241 21 12 0,000 5,725E-03 0,01234475 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 5,725E-03 0,01233387 ! entry into host cell GO:0030260 34 12 0,000 5,725E-03 0,012323 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 5,725E-03 0,01231215 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 5,725E-03 0,01230132 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 5,725E-03 0,01229051 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 5,725E-03 0,01227972 ! protein targeting to peroxisome GO:0006625 27 12 0,000 5,725E-03 0,01226895 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 5,725E-03 0,0122582 ! regulation of phagocytosis GO:0050764 17 12 0,000 5,725E-03 0,01224746 ! snRNA metabolic process GO:0016073 30 12 0,000 5,725E-03 0,01223675 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 5,725E-03 0,01222605 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 5,725E-03 0,01221537 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 5,725E-03 0,01220471 ! cranial nerve development GO:0021545 23 12 0,000 5,725E-03 0,01219407 ! fucose catabolic process GO:0019317 25 12 0,000 5,725E-03 0,01218345 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 5,725E-03 0,01217285 ! histone acetylation GO:0016573 27 12 0,000 5,725E-03 0,01216226 ! mRNA polyadenylation GO:0006378 24 12 0,000 5,725E-03 0,0121517 ! autonomic nervous system development GO:0048483 24 12 0,000 5,725E-03 0,01214115 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 5,725E-03 0,01213062 ! zymogen activation GO:0031638 18 12 0,000 5,725E-03 0,01212011 ! peptidyl-lysine modification GO:0018205 21 12 0,000 5,725E-03 0,01210961 ! T cell homeostasis GO:0043029 28 12 0,000 5,725E-03 0,01209914 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 5,725E-03 0,01208868 ! glutathione biosynthetic process GO:0006750 15 12 0,000 5,725E-03 0,01207824 ! regulation of leukocyte migration GO:0002685 29 12 0,000 5,725E-03 0,01206782 ! oocyte differentiation GO:0009994 21 12 0,000 5,725E-03 0,01205742 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 5,725E-03 0,01204703 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 5,725E-03 0,01203666 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 5,725E-03 0,01202631 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 5,725E-03 0,01201598 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 5,725E-03 0,01200567 ! defense response to fungus GO:0050832 15 12 0,000 5,725E-03 0,01199537 ! developmental induction GO:0031128 22 12 0,000 5,725E-03 0,01198509 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 5,725E-03 0,01197483 ! lamellipodium assembly GO:0030032 24 12 0,000 5,725E-03 0,01196459 ! response to cold GO:0009409 17 12 0,000 5,725E-03 0,01195436 ! establishment of cell polarity GO:0030010 21 12 0,000 5,725E-03 0,01194415 ! regulation of synapse organization GO:0050807 18 12 0,000 5,725E-03 0,01193396 ! localization within membrane GO:0051668 26 12 0,000 5,725E-03 0,01192379 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 6,201E-03 0,01290353 ! cGMP metabolic process GO:0046068 18 13 0,000 6,201E-03 0,01289255 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 6,201E-03 0,01288159 ! regulation of chemokine production GO:0032642 18 13 0,000 6,201E-03 0,01287064 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 6,201E-03 0,01285972 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 6,201E-03 0,01284881 ! peroxisomal transport GO:0043574 28 13 0,000 6,201E-03 0,01283792 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 6,201E-03 0,01282705 ! cartilage condensation GO:0001502 22 13 0,000 6,201E-03 0,0128162 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 6,201E-03 0,01280536 ! organelle fusion GO:0048284 36 13 0,000 6,201E-03 0,01279455 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 6,201E-03 0,01278375 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 6,201E-03 0,01277297 ! pseudouridine synthesis GO:0001522 19 13 0,000 6,201E-03 0,01276221 ! endocrine pancreas development GO:0031018 25 13 0,000 6,201E-03 0,01275147 ! positive regulation of cell growth GO:0030307 24 13 0,000 6,201E-03 0,01274074 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 6,201E-03 0,01273004 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 6,201E-03 0,01271935 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 6,201E-03 0,01270868 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 6,201E-03 0,01269803 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 6,201E-03 0,01268739 ! methionine metabolic process GO:0006555 31 13 0,000 6,201E-03 0,01267677 ! plasma membrane organization GO:0007009 27 13 0,000 6,201E-03 0,01266617 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 6,201E-03 0,01265559 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 6,201E-03 0,01264503 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 6,201E-03 0,01263448 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 6,201E-03 0,01262395 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 6,201E-03 0,01261344 ! cytokine metabolic process GO:0042107 24 13 0,000 6,201E-03 0,01260295 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 6,201E-03 0,01259247 ! exocrine system development GO:0035272 34 13 0,000 6,201E-03 0,01258201 ! asymmetric protein localization GO:0008105 24 13 0,000 6,201E-03 0,01257157 ! membrane protein proteolysis GO:0033619 33 13 0,000 6,201E-03 0,01256115 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 6,201E-03 0,01255074 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 6,201E-03 0,01254035 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 6,201E-03 0,01252998 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 6,201E-03 0,01251962 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 6,201E-03 0,01250929 ! protein homotetramerization GO:0051289 24 13 0,000 6,201E-03 0,01249896 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 6,201E-03 0,01248866 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 6,201E-03 0,01247837 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 6,201E-03 0,0124681 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 6,201E-03 0,01245785 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 6,201E-03 0,01244761 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 6,201E-03 0,01243739 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 6,201E-03 0,01242719 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 6,201E-03 0,012417 ! histone methylation GO:0016571 29 13 0,000 6,201E-03 0,01240683 ! chromatin silencing GO:0006342 29 13 0,000 6,201E-03 0,01239668 ! gland morphogenesis GO:0022612 31 13 0,000 6,201E-03 0,01238655 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 6,201E-03 0,01237643 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 6,201E-03 0,01236632 ! regulation of epidermis development GO:0045682 19 13 0,000 6,201E-03 0,01235624 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 6,201E-03 0,01234617 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 6,201E-03 0,01233611 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 6,201E-03 0,01232607 ! spleen development GO:0048536 24 13 0,000 6,201E-03 0,01231605 ! regulation of mRNA stability GO:0043488 32 13 0,000 6,201E-03 0,01230605 ! digestive tract morphogenesis GO:0048546 31 13 0,000 6,201E-03 0,01229606 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 6,201E-03 0,01228609 ! anterior/posterior axis specification GO:0009948 22 13 0,000 6,201E-03 0,01227613 ! regulation of RNA splicing GO:0043484 22 13 0,000 6,201E-03 0,01226619 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 6,201E-03 0,01225627 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 6,201E-03 0,01224636 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 6,201E-03 0,01223647 ! mRNA 3'-end processing GO:0031124 25 13 0,000 6,201E-03 0,01222659 ! insulin secretion GO:0030073 24 13 0,000 6,201E-03 0,01221673 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 6,201E-03 0,01220689 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 6,201E-03 0,01219706 ! acrosome reaction GO:0007340 19 13 0,000 6,201E-03 0,01218724 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 6,201E-03 0,01217745 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 6,201E-03 0,01216767 ! rRNA transcription GO:0009303 28 14 0,000 6,676E-03 0,01309018 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 6,676E-03 0,01307968 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 6,676E-03 0,0130692 ! water transport GO:0006833 21 14 0,000 6,676E-03 0,01305874 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 6,676E-03 0,01304829 ! non-recombinational repair GO:0000726 29 14 0,000 6,676E-03 0,01303786 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 6,676E-03 0,01302745 ! retina development in camera-type eye GO:0060041 28 14 0,000 6,676E-03 0,01301705 ! hair follicle morphogenesis GO:0031069 27 14 0,000 6,676E-03 0,01300667 ! RNA polyadenylation GO:0043631 32 14 0,000 6,676E-03 0,01299631 ! lipid localization GO:0010876 32 14 0,000 6,676E-03 0,01298596 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 6,676E-03 0,01297563 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 6,676E-03 0,01296531 ! regulated secretory pathway GO:0045055 24 14 0,000 6,676E-03 0,01295501 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 6,676E-03 0,01294473 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 6,676E-03 0,01293447 ! arginine metabolic process GO:0006525 21 14 0,000 6,676E-03 0,01292422 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 6,676E-03 0,01291399 ! cell-cell junction assembly GO:0007043 32 14 0,000 6,676E-03 0,01290377 ! regulation of heart rate GO:0002027 25 14 0,000 6,676E-03 0,01289357 ! fear response GO:0042596 34 14 0,000 6,676E-03 0,01288338 ! organic alcohol transport GO:0015850 29 14 0,000 6,676E-03 0,01287322 ! negative regulation of caspase activity GO:0043154 23 14 0,000 6,676E-03 0,01286306 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 6,676E-03 0,01285293 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 6,676E-03 0,01284281 ! neutral amino acid transport GO:0015804 28 14 0,000 6,676E-03 0,0128327 ! bone mineralization GO:0030282 18 14 0,000 6,676E-03 0,01282261 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 6,676E-03 0,01281254 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 6,676E-03 0,01280248 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 6,676E-03 0,01279244 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 6,676E-03 0,01278242 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 6,676E-03 0,01277241 ! regulation of cellular pH GO:0030641 27 14 0,000 6,676E-03 0,01276241 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 6,676E-03 0,01275243 ! ribosome assembly GO:0042255 18 14 0,000 6,676E-03 0,01274247 ! cerebellum development GO:0021549 23 14 0,000 6,676E-03 0,01273252 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 6,676E-03 0,01272259 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 6,676E-03 0,01271268 ! negative regulation of protein secretion GO:0050709 30 14 0,000 6,676E-03 0,01270278 ! response to gamma radiation GO:0010332 30 14 0,000 6,676E-03 0,01269289 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 6,676E-03 0,01268302 ! NADP metabolic process GO:0006739 24 14 0,000 6,676E-03 0,01267317 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 6,676E-03 0,01266333 ! oxygen transport GO:0015671 22 14 0,000 6,676E-03 0,0126535 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 6,676E-03 0,01264369 ! male genitalia development GO:0030539 26 14 0,000 6,676E-03 0,0126339 ! regulation of RNA stability GO:0043487 33 14 0,000 6,676E-03 0,01262412 ! regulation of axon extension GO:0030516 43 14 0,000 6,676E-03 0,01261436 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 6,676E-03 0,01260461 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 6,676E-03 0,01259488 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 6,676E-03 0,01258516 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 7,152E-03 0,01347067 ! lactation GO:0007595 30 15 0,000 7,152E-03 0,01346029 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 7,152E-03 0,01344993 ! reproductive cellular process GO:0048610 22 15 0,000 7,152E-03 0,01343958 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 7,152E-03 0,01342925 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 7,152E-03 0,01341894 ! superoxide anion generation GO:0042554 22 15 0,000 7,152E-03 0,01340864 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 7,152E-03 0,01339836 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 7,152E-03 0,01338809 ! phospholipid catabolic process GO:0009395 27 15 0,000 7,152E-03 0,01337784 ! copper ion transport GO:0006825 22 15 0,000 7,152E-03 0,0133676 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 7,152E-03 0,01335738 ! cardiac muscle contraction GO:0060048 28 15 0,000 7,152E-03 0,01334718 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 7,152E-03 0,01333699 ! sulfate transport GO:0008272 27 15 0,000 7,152E-03 0,01332682 ! response to cAMP GO:0051591 25 15 0,000 7,152E-03 0,01331666 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 7,152E-03 0,01330652 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 7,152E-03 0,01329639 ! regulation of mRNA processing GO:0050684 26 15 0,000 7,152E-03 0,01328628 ! response to hexose stimulus GO:0009746 25 15 0,000 7,152E-03 0,01327618 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 7,152E-03 0,0132661 ! glycoprotein catabolic process GO:0006516 33 15 0,000 7,152E-03 0,01325604 ! vesicle coating GO:0006901 38 15 0,000 7,152E-03 0,01324599 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 7,152E-03 0,01323595 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 7,152E-03 0,01322593 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 7,152E-03 0,01321593 ! regulation of exocytosis GO:0017157 26 15 0,000 7,152E-03 0,01320594 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 7,152E-03 0,01319597 ! G1/S transition checkpoint GO:0031575 37 15 0,000 7,152E-03 0,01318601 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 7,152E-03 0,01317606 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 7,152E-03 0,01316613 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 7,152E-03 0,01315622 ! regulation of vasodilation GO:0042312 27 15 0,000 7,152E-03 0,01314632 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 7,152E-03 0,01313644 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 7,152E-03 0,01312657 ! water homeostasis GO:0030104 28 15 0,000 7,152E-03 0,01311671 ! cofactor transport GO:0051181 30 15 0,000 7,152E-03 0,01310687 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 7,152E-03 0,01309705 ! muscle maintenance GO:0046716 26 15 0,000 7,152E-03 0,01308724 ! protein-chromophore linkage GO:0018298 25 15 0,000 7,152E-03 0,01307744 ! intestinal absorption GO:0050892 31 15 0,000 7,152E-03 0,01306766 ! dopamine metabolic process GO:0042417 35 15 0,000 7,152E-03 0,01305789 ! cAMP biosynthetic process GO:0006171 25 15 0,000 7,152E-03 0,01304814 ! heme biosynthetic process GO:0006783 33 15 0,000 7,152E-03 0,0130384 ! cell killing GO:0001906 32 15 0,000 7,152E-03 0,01302868 ! lymphocyte homeostasis GO:0002260 33 15 0,000 7,152E-03 0,01301897 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 7,152E-03 0,01300928 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 7,152E-03 0,0129996 ! L-fucose metabolic process GO:0042354 33 15 0,000 7,152E-03 0,01298993 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 7,152E-03 0,01298028 ! actin filament polymerization GO:0030041 27 15 0,000 7,152E-03 0,01297065 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 7,152E-03 0,01296102 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 7,627E-03 0,01381174 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 7,627E-03 0,01380151 ! positive regulation of cell size GO:0045793 29 16 0,000 7,627E-03 0,01379129 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 7,627E-03 0,01378109 ! dicarboxylic acid transport GO:0006835 47 16 0,000 7,627E-03 0,0137709 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 7,627E-03 0,01376073 ! bone remodeling GO:0046849 28 16 0,000 7,627E-03 0,01375058 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 7,627E-03 0,01374044 ! heterophilic cell adhesion GO:0007157 43 16 0,000 7,627E-03 0,01373031 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 7,627E-03 0,0137202 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 7,627E-03 0,0137101 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 7,627E-03 0,01370002 ! positive regulation of ion transport GO:0043270 23 16 0,000 7,627E-03 0,01368996 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 7,627E-03 0,01367991 ! startle response GO:0001964 28 16 0,000 7,627E-03 0,01366987 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 7,627E-03 0,01365985 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 7,627E-03 0,01364984 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 7,627E-03 0,01363985 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 7,627E-03 0,01362987 ! protein polyubiquitination GO:0000209 41 16 0,000 7,627E-03 0,01361991 ! glutamate metabolic process GO:0006536 25 16 0,000 7,627E-03 0,01360996 ! pituitary gland development GO:0021983 30 16 0,000 7,627E-03 0,01360002 ! response to osmotic stress GO:0006970 27 16 0,000 7,627E-03 0,0135901 ! lysosomal transport GO:0007041 31 16 0,000 7,627E-03 0,0135802 ! fructose metabolic process GO:0006000 25 16 0,000 7,627E-03 0,01357031 ! L-amino acid transport GO:0015807 33 16 0,000 7,627E-03 0,01356043 ! stem cell development GO:0048864 46 16 0,000 7,627E-03 0,01355057 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 7,627E-03 0,01354072 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 7,627E-03 0,01353089 ! intermediate filament-based process GO:0045103 36 16 0,000 7,627E-03 0,01352107 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 7,627E-03 0,01351126 ! negative regulation of immune response GO:0050777 38 16 0,000 7,627E-03 0,01350147 ! axon cargo transport GO:0008088 46 16 0,000 7,627E-03 0,0134917 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 7,627E-03 0,01348193 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 7,627E-03 0,01347219 ! DNA replication initiation GO:0006270 28 16 0,000 7,627E-03 0,01346245 ! neuron recognition GO:0008038 40 16 0,000 7,627E-03 0,01345273 ! mRNA splice site selection GO:0006376 44 16 0,000 7,627E-03 0,01344302 ! tissue regeneration GO:0042246 27 16 0,000 7,627E-03 0,01343333 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 7,627E-03 0,01342365 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 7,627E-03 0,01341399 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 7,627E-03 0,01340434 ! biomineral formation GO:0031214 22 16 0,000 7,627E-03 0,0133947 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 7,627E-03 0,01338508 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 7,627E-03 0,01337547 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 7,627E-03 0,01336588 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 7,627E-03 0,0133563 ! regulation of ATPase activity GO:0043462 26 16 0,000 7,627E-03 0,01334673 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 7,627E-03 0,01333717 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 7,627E-03 0,01332763 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 7,627E-03 0,01331811 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 7,627E-03 0,01330859 ! peptide hormone processing GO:0016486 27 16 0,000 7,627E-03 0,01329909 ! positive regulation of cell killing GO:0031343 36 17 0,000 8,102E-03 0,01411703 ! metencephalon development GO:0022037 32 17 0,000 8,102E-03 0,01410697 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 8,102E-03 0,01409692 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 8,102E-03 0,01408689 ! signal complex assembly GO:0007172 47 17 0,000 8,102E-03 0,01407687 ! filopodium assembly GO:0046847 42 17 0,000 8,102E-03 0,01406687 ! endothelial cell migration GO:0043542 31 17 0,000 8,102E-03 0,01405688 ! gene silencing by RNA GO:0031047 38 17 0,000 8,102E-03 0,0140469 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 8,102E-03 0,01403694 ! glial cell development GO:0021782 28 17 0,000 8,102E-03 0,01402699 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 8,102E-03 0,01401706 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 8,102E-03 0,01400714 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 8,102E-03 0,01399723 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 8,102E-03 0,01398734 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 8,102E-03 0,01397746 ! myoblast differentiation GO:0045445 50 17 0,000 8,102E-03 0,01396759 ! activation of MAPKK activity GO:0000186 43 17 0,000 8,102E-03 0,01395774 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 8,102E-03 0,01394791 ! regulation of survival gene product expression GO:0045884 38 17 0,000 8,102E-03 0,01393809 ! cardiac muscle tissue development GO:0048738 34 17 0,000 8,102E-03 0,01392828 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 8,102E-03 0,01391848 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 8,102E-03 0,0139087 ! complement activation, alternative pathway GO:0006957 19 17 0,000 8,102E-03 0,01389893 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 8,102E-03 0,01388918 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 8,102E-03 0,01387944 ! membrane budding GO:0006900 42 17 0,000 8,102E-03 0,01386971 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 8,102E-03 0,01386 ! regulation of protein binding GO:0043393 33 17 0,000 8,102E-03 0,0138503 ! nucleobase metabolic process GO:0009112 43 17 0,000 8,102E-03 0,01384062 ! DNA unwinding during replication GO:0006268 26 17 0,000 8,102E-03 0,01383094 ! genitalia development GO:0048806 32 17 0,000 8,102E-03 0,01382129 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 8,102E-03 0,01381164 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 8,102E-03 0,01380201 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 8,102E-03 0,01379239 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 8,102E-03 0,01378279 ! neutrophil chemotaxis GO:0030593 29 17 0,000 8,102E-03 0,0137732 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 8,102E-03 0,01376362 ! steroid catabolic process GO:0006706 34 17 0,000 8,102E-03 0,01375405 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 8,102E-03 0,0137445 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 8,102E-03 0,01373496 ! gas transport GO:0015669 26 17 0,000 8,102E-03 0,01372544 ! organic cation transport GO:0015695 32 17 0,000 8,102E-03 0,01371593 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 8,102E-03 0,01370643 ! RNA 3'-end processing GO:0031123 37 17 0,000 8,102E-03 0,01369694 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 8,102E-03 0,01368747 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 8,576E-03 0,01447934 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 8,576E-03 0,01446934 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 8,576E-03 0,01445936 ! limbic system development GO:0021761 40 18 0,000 8,576E-03 0,01444939 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 8,576E-03 0,01443943 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 8,576E-03 0,01442948 ! adult walking behavior GO:0007628 36 18 0,000 8,576E-03 0,01441955 ! patterning of blood vessels GO:0001569 43 18 0,000 8,576E-03 0,01440964 ! heart looping GO:0001947 34 18 0,000 8,576E-03 0,01439973 ! ciliary or flagellar motility GO:0001539 32 18 0,000 8,576E-03 0,01438984 ! centrosome cycle GO:0007098 26 18 0,000 8,576E-03 0,01437997 ! positive regulation of proteolysis GO:0045862 36 18 0,000 8,576E-03 0,0143701 ! regulation of defense response to virus GO:0050688 35 18 0,000 8,576E-03 0,01436025 ! epidermis morphogenesis GO:0048730 43 18 0,000 8,576E-03 0,01435042 ! glycine metabolic process GO:0006544 30 18 0,000 8,576E-03 0,0143406 ! glutamine metabolic process GO:0006541 29 18 0,000 8,576E-03 0,01433079 ! response to retinoic acid GO:0032526 31 18 0,000 8,576E-03 0,01432099 ! cell-substrate junction assembly GO:0007044 56 18 0,000 8,576E-03 0,01431121 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 0,000 8,576E-03 0,01430144 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 8,576E-03 0,01429168 ! DNA integration GO:0015074 32 18 0,000 8,576E-03 0,01428194 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 8,576E-03 0,01427221 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 8,576E-03 0,0142625 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 8,576E-03 0,0142528 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 8,576E-03 0,01424311 ! neural crest cell migration GO:0001755 41 18 0,000 8,576E-03 0,01423343 ! long-chain fatty acid transport GO:0015909 32 18 0,000 8,576E-03 0,01422377 ! sphingolipid catabolic process GO:0030149 32 18 0,000 8,576E-03 0,01421412 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 8,576E-03 0,01420448 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 8,576E-03 0,01419486 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 8,576E-03 0,01418525 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 8,576E-03 0,01417565 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 8,576E-03 0,01416606 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 8,576E-03 0,01415649 ! detection of bacterium GO:0016045 22 18 0,000 8,576E-03 0,01414693 ! nerve development GO:0021675 34 18 0,000 8,576E-03 0,01413739 ! defense response to virus GO:0051607 43 18 0,000 8,576E-03 0,01412786 ! microspike assembly GO:0030035 46 18 0,000 8,576E-03 0,01411834 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 8,576E-03 0,01410883 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 8,576E-03 0,01409933 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 9,051E-03 0,01486928 ! positive regulation of translation GO:0045727 31 19 0,000 9,051E-03 0,01485928 ! negative regulation of defense response GO:0031348 27 19 0,000 9,051E-03 0,0148493 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 9,051E-03 0,01483934 ! neuron maturation GO:0042551 46 19 0,000 9,051E-03 0,01482939 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 9,051E-03 0,01481945 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 9,051E-03 0,01480952 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 9,051E-03 0,01479961 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 9,051E-03 0,01478971 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 9,051E-03 0,01477982 ! inositol metabolic process GO:0006020 33 19 0,000 9,051E-03 0,01476995 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 9,051E-03 0,01476009 ! memory GO:0007613 34 19 0,000 9,051E-03 0,01475024 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 9,051E-03 0,01474041 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 9,051E-03 0,01473059 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 9,051E-03 0,01472078 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 9,051E-03 0,01471099 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 9,051E-03 0,01470121 ! cerebral cortex development GO:0021987 40 19 0,000 9,051E-03 0,01469144 ! pigmentation during development GO:0048066 42 19 0,000 9,051E-03 0,01468168 ! response to vitamin A GO:0033189 32 19 0,000 9,051E-03 0,01467194 ! heme metabolic process GO:0042168 40 19 0,000 9,051E-03 0,01466221 ! neuromuscular junction development GO:0007528 43 19 0,000 9,051E-03 0,01465249 ! response to lipopolysaccharide GO:0032496 34 19 0,000 9,051E-03 0,01464279 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 9,051E-03 0,0146331 ! response to fungus GO:0009620 26 19 0,000 9,051E-03 0,01462342 ! peptide cross-linking GO:0018149 39 19 0,000 9,051E-03 0,01461376 ! protein export from nucleus GO:0006611 40 19 0,000 9,051E-03 0,0146041 ! heart process GO:0003015 32 19 0,000 9,051E-03 0,01459447 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 9,051E-03 0,01458484 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 9,051E-03 0,01457522 ! visual learning GO:0008542 38 19 0,000 9,051E-03 0,01456562 ! cellular pigmentation GO:0033059 37 19 0,000 9,051E-03 0,01455603 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 9,051E-03 0,01454646 ! peptide biosynthetic process GO:0043043 26 19 0,000 9,051E-03 0,01453689 ! vitamin transport GO:0051180 31 19 0,000 9,051E-03 0,01452734 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 9,051E-03 0,0145178 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 9,051E-03 0,01450828 ! proximal/distal pattern formation GO:0009954 33 19 0,000 9,051E-03 0,01449876 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 9,051E-03 0,01448926 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 9,051E-03 0,01447977 ! cilium assembly GO:0042384 38 19 0,000 9,051E-03 0,0144703 ! peptide hormone secretion GO:0030072 32 19 0,000 9,051E-03 0,01446083 ! protein secretion GO:0009306 45 20 0,000 9,525E-03 0,01520856 ! protein import into nucleus, docking GO:0000059 42 20 0,000 9,525E-03 0,01519863 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 9,525E-03 0,01518871 ! positive regulation of ossification GO:0045778 50 20 0,000 9,525E-03 0,0151788 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 9,525E-03 0,0151689 ! skin development GO:0043588 42 20 0,000 9,525E-03 0,01515902 ! phosphoinositide phosphorylation GO:0046854 40 20 0,000 9,525E-03 0,01514915 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 9,525E-03 0,0151393 ! protein amino acid acetylation GO:0006473 41 20 0,000 9,525E-03 0,01512945 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 0,000 9,525E-03 0,01511962 ! aminoglycan catabolic process GO:0006026 25 20 0,000 9,525E-03 0,0151098 ! response to vitamin GO:0033273 36 20 0,000 9,525E-03 0,0151 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 9,525E-03 0,01509021 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 9,525E-03 0,01508043 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 9,525E-03 0,01507066 ! bile acid metabolic process GO:0008206 34 20 0,000 9,525E-03 0,0150609 ! response to alkaloid GO:0043279 38 20 0,000 9,525E-03 0,01505116 ! retinoid metabolic process GO:0001523 34 20 0,000 9,525E-03 0,01504143 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 9,525E-03 0,01503172 ! apoptotic mitochondrial changes GO:0008637 42 20 0,000 9,525E-03 0,01502201 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 9,525E-03 0,01501232 ! DNA duplex unwinding GO:0032508 30 20 0,000 9,525E-03 0,01500264 GO:0032392|DNA geometric change, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 9,525E-03 0,01499298 ! actin filament bundle formation GO:0051017 47 20 0,000 9,525E-03 0,01498332 ! body fluid secretion GO:0007589 33 20 0,000 9,525E-03 0,01497368 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 9,525E-03 0,01496405 ! peptide secretion GO:0002790 38 20 0,000 9,525E-03 0,01495443 ! behavioral interaction between organisms GO:0051705 47 20 0,000 9,525E-03 0,01494483 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 9,525E-03 0,01493524 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 9,525E-03 0,01492566 ! protein localization in mitochondrion GO:0070585 39 20 0,000 9,525E-03 0,01491609 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 9,525E-03 0,01490653 ! cell-cell junction organization GO:0045216 43 20 0,000 9,525E-03 0,01489699 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 9,525E-03 0,01488746 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 9,525E-03 0,01487794 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 9,525E-03 0,01486843 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 9,525E-03 0,01485894 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 9,525E-03 0,01484946 ! regulation of glucose import GO:0046324 30 20 0,000 9,525E-03 0,01483999 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 9,525E-03 0,01483053 ! negative regulation of T cell activation GO:0050868 41 20 0,000 9,525E-03 0,01482108 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 9,525E-03 0,01481165 ! negative regulation of translation GO:0017148 32 20 0,000 9,525E-03 0,01480223 ! negative regulation of coagulation GO:0050819 30 20 0,000 9,525E-03 0,01479282 ! regulation of cell killing GO:0031341 46 21 0,000 9,999E-03 0,0155191 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 9,999E-03 0,01550924 ! hormone secretion GO:0046879 39 21 0,000 9,999E-03 0,0154994 ! lipid phosphorylation GO:0046834 43 21 0,000 9,999E-03 0,01548957 ! cAMP metabolic process GO:0046058 41 21 0,000 9,999E-03 0,01547976 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 9,999E-03 0,01546996 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 9,999E-03 0,01546016 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 9,999E-03 0,01545039 ! ovarian follicle development GO:0001541 39 21 0,000 9,999E-03 0,01544062 ! smooth muscle contraction GO:0006939 48 21 0,000 9,999E-03 0,01543087 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 0,000 9,999E-03 0,01542112 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 9,999E-03 0,01541139 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 9,999E-03 0,01540168 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 9,999E-03 0,01539197 ! plasma membrane fusion GO:0045026 33 21 0,000 9,999E-03 0,01538228 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 9,999E-03 0,0153726 ! prostaglandin metabolic process GO:0006693 43 21 0,000 9,999E-03 0,01536293 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 9,999E-03 0,01535327 ! sensory perception of pain GO:0019233 33 21 0,000 9,999E-03 0,01534363 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 9,999E-03 0,015334 ! diencephalon development GO:0021536 36 21 0,000 9,999E-03 0,01532438 ! collagen fibril organization GO:0030199 62 21 0,000 9,999E-03 0,01531477 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 9,999E-03 0,01530518 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 9,999E-03 0,01529559 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 9,999E-03 0,01528602 ! vitamin A metabolic process GO:0006776 35 21 0,000 9,999E-03 0,01527646 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 9,999E-03 0,01526691 ! collagen catabolic process GO:0030574 29 21 0,000 9,999E-03 0,01525738 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 9,999E-03 0,01524785 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 9,999E-03 0,01523834 ! sperm-egg recognition GO:0035036 23 21 0,000 9,999E-03 0,01522884 ! actin filament-based movement GO:0030048 47 21 0,000 9,999E-03 0,01521935 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 9,999E-03 0,01520988 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,01047257 0,01592066 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,01047257 0,01591076 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,01047257 0,01590087 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,01047257 0,01589099 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,01047257 0,01588113 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,01047257 0,01587128 ! microtubule-based transport GO:0010970 59 22 0,000 0,01047257 0,01586144 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,01047257 0,01585161 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,01047257 0,0158418 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,01047257 0,01583199 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,01047257 0,0158222 ! cellular response to starvation GO:0009267 37 22 0,000 0,01047257 0,01581242 ! vacuolar transport GO:0007034 41 22 0,000 0,01047257 0,01580266 ! central nervous system neuron development GO:0021954 47 22 0,000 0,01047257 0,0157929 ! fucose metabolic process GO:0006004 44 22 0,000 0,01047257 0,01578316 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,01047257 0,01577343 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,01047257 0,01576371 ! ureteric bud development GO:0001657 50 22 0,000 0,01047257 0,015754 ! cell aging GO:0007569 48 22 0,000 0,01047257 0,01574431 ! stem cell differentiation GO:0048863 57 22 0,000 0,01047257 0,01573462 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,01047257 0,01572495 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,01047257 0,01571529 ! cytolysis GO:0019835 27 22 0,000 0,01047257 0,01570565 ! renal system process GO:0003014 42 22 0,000 0,01047257 0,01569601 ! vasodilation GO:0042311 40 22 0,000 0,01047257 0,01568639 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,01047257 0,01567678 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,01047257 0,01566718 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 0,01047257 0,01565759 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,01047257 0,01564801 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,01047257 0,01563845 ! positive regulation of intracellular transport GO:0032388 42 22 0,000 0,01047257 0,01562889 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,01047257 0,01561935 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,01047257 0,01560982 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,01047257 0,0156003 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,01047257 0,0155908 ! sarcomere organization GO:0045214 32 22 0,000 0,01047257 0,0155813 ! positive regulation of B cell activation GO:0050871 42 22 0,000 0,01047257 0,01557182 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,01047257 0,01556235 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,01047257 0,01555289 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,01047257 0,01554344 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,01047257 0,015534 ! gut development GO:0048565 44 22 0,000 0,01047257 0,01552458 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,01047257 0,01551516 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,01047257 0,01550576 ! protein stabilization GO:0050821 41 22 0,000 0,01047257 0,01549637 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,01094614 0,0161873 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,01094614 0,01617751 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,01094614 0,01616773 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,01094614 0,01615796 ! gluconeogenesis GO:0006094 38 23 0,000 0,01094614 0,0161482 ! glycerol metabolic process GO:0006071 40 23 0,000 0,01094614 0,01613845 ! viral genome replication GO:0019079 44 23 0,000 0,01094614 0,01612872 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,01094614 0,016119 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,01094614 0,01610929 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,01094614 0,01609959 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,01094614 0,0160899 ! regeneration GO:0031099 42 23 0,000 0,01094614 0,01608023 ! axis specification GO:0009798 43 23 0,000 0,01094614 0,01607056 ! visual behavior GO:0007632 46 23 0,000 0,01094614 0,01606091 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,01094614 0,01605127 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 0,01094614 0,01604164 ! response to ethanol GO:0045471 47 23 0,000 0,01094614 0,01603203 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,01094614 0,01602242 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,01094614 0,01601283 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,01094614 0,01600324 ! peroxisome organization GO:0007031 43 23 0,000 0,01094614 0,01599367 ! lysosome organization GO:0007040 47 23 0,000 0,01094614 0,01598411 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,01094614 0,01597456 ! vesicle targeting GO:0006903 49 23 0,000 0,01094614 0,01596503 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,01094614 0,0159555 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,01094614 0,01594599 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,01094614 0,01593648 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,01094614 0,01592699 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,01094614 0,01591751 ! DNA modification GO:0006304 36 23 0,000 0,01094614 0,01590804 ! fatty acid transport GO:0015908 47 23 0,000 0,01094614 0,01589858 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,01094614 0,01588914 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,01094614 0,0158797 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,01094614 0,01587028 ! hormone transport GO:0009914 41 23 0,000 0,01094614 0,01586086 ! cell-cell recognition GO:0009988 28 23 0,000 0,01094614 0,01585146 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,01094614 0,01584207 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,01094614 0,01583269 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,01094614 0,01582332 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,01141949 0,01649782 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,01141949 0,01648807 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,01141949 0,01647833 ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,01141949 0,0164686 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,01141949 0,01645889 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,01141949 0,01644918 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,01141949 0,01643949 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,01141949 0,01642981 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,01141949 0,01642014 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,01141949 0,01641048 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,01141949 0,01640083 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 0,000 0,01141949 0,0163912 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,01141949 0,01638157 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,01141949 0,01637196 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,01141949 0,01636236 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,01141949 0,01635276 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,01141949 0,01634318 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,01141949 0,01633362 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,01141949 0,01632406 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,01141949 0,01631451 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 52 24 0,000 0,01141949 0,01630498 ! leukotriene metabolic process GO:0006691 47 24 0,000 0,01141949 0,01629545 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,01141949 0,01628594 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,01141949 0,01627644 ! membrane depolarization GO:0051899 45 24 0,000 0,01141949 0,01626695 ! pallium development GO:0021543 56 24 0,000 0,01141949 0,01625747 ! oogenesis GO:0048477 44 24 0,000 0,01141949 0,016248 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,01141949 0,01623854 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,01141949 0,0162291 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 0,01141949 0,01621966 ! platelet activation GO:0030168 41 24 0,000 0,01141949 0,01621024 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,01141949 0,01620082 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,01141949 0,01619142 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,01141949 0,01618203 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,01141949 0,01617265 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,01141949 0,01616328 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,01141949 0,01615392 ! regulation of amine transport GO:0051952 41 24 0,000 0,01141949 0,01614457 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,01141949 0,01613523 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,01189263 0,01679404 ! positive regulation of fibroblast proliferation GO:0048146 48 25 0,000 0,01189263 0,01678434 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,01189263 0,01677465 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,01189263 0,01676497 ! leukocyte adhesion GO:0007159 55 25 0,000 0,01189263 0,0167553 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,01189263 0,01674564 ! phototransduction GO:0007602 37 25 0,000 0,01189263 0,016736 ! keratinization GO:0031424 37 25 0,000 0,01189263 0,01672636 ! vasculogenesis GO:0001570 49 25 0,000 0,01189263 0,01671674 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,01189263 0,01670713 ! vacuole organization GO:0007033 49 25 0,000 0,01189263 0,01669752 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,01189263 0,01668793 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,01189263 0,01667835 ! receptor metabolic process GO:0043112 53 25 0,000 0,01189263 0,01666879 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,01189263 0,01665923 ! regulation of behavior GO:0050795 48 25 0,000 0,01189263 0,01664968 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,01189263 0,01664014 ! interaction with host GO:0051701 66 25 0,000 0,01189263 0,01663062 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,01189263 0,01662111 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,01189263 0,0166116 ! immunoglobulin production GO:0002377 62 25 0,000 0,01189263 0,01660211 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,01189263 0,01659263 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,01189263 0,01658316 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,01189263 0,0165737 ! liver development GO:0001889 55 25 0,000 0,01189263 0,01656425 ! protein tetramerization GO:0051262 57 25 0,000 0,01189263 0,01655481 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,01236555 0,01720333 ! myelination GO:0042552 50 26 0,000 0,01236555 0,01719354 ! initiation of viral infection GO:0019059 60 26 0,000 0,01236555 0,01718376 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,01236555 0,01717399 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,01236555 0,01716423 ! molting cycle process GO:0022404 52 26 0,000 0,01236555 0,01715449 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,01236555 0,01714475 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,01236555 0,01713502 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,01236555 0,01712531 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,01236555 0,01711561 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,01236555 0,01710592 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,01236555 0,01709624 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,01236555 0,01708657 ! digestive system process GO:0022600 49 26 0,000 0,01236555 0,01707691 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,01236555 0,01706726 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,01236555 0,01705762 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 0,000 0,01236555 0,017048 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,01236555 0,01703838 ! osteoblast differentiation GO:0001649 63 26 0,000 0,01236555 0,01702878 ! neural crest cell development GO:0014032 59 26 0,000 0,01236555 0,01701918 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,01236555 0,0170096 ! negative regulation of cell development GO:0010721 83 26 0,000 0,01236555 0,01700003 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,01236555 0,01699047 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,01236555 0,01698092 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,01236555 0,01697138 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,01236555 0,01696185 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,01236555 0,01695233 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,01236555 0,01694282 ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,01236555 0,01693332 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,01236555 0,01692384 ! blastocyst development GO:0001824 50 26 0,000 0,01236555 0,01691436 ! telomere organization GO:0032200 46 26 0,000 0,01236555 0,0169049 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,01236555 0,01689544 ! neural tube closure GO:0001843 58 26 0,000 0,01236555 0,016886 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,01236555 0,01687656 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,01236555 0,01686714 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,01236555 0,01685773 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,01283827 0,01749241 ! embryonic pattern specification GO:0009880 49 27 0,000 0,01283827 0,01748266 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,01283827 0,01747292 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,01283827 0,01746319 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,01283827 0,01745347 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,01283827 0,01744376 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,01283827 0,01743407 ! iron ion transport GO:0006826 65 27 0,000 0,01283827 0,01742438 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,01283827 0,01741471 ! superoxide metabolic process GO:0006801 41 27 0,000 0,01283827 0,01740504 ! tube lumen formation GO:0035148 59 27 0,000 0,01283827 0,01739539 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,01283827 0,01738574 ! insulin receptor signaling pathway GO:0008286 66 27 0,000 0,01283827 0,01737611 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,01283827 0,01736649 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,01283827 0,01735688 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,01283827 0,01734728 ! response to starvation GO:0042594 47 27 0,000 0,01283827 0,01733769 ! response to toxin GO:0009636 49 27 0,000 0,01283827 0,01732811 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,01283827 0,01731854 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,01283827 0,01730899 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,01283827 0,01729944 ! leukocyte proliferation GO:0070661 59 27 0,000 0,01283827 0,0172899 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,01283827 0,01728038 ! regulation of fibroblast proliferation GO:0048145 56 28 0,000 0,01331077 0,0179065 ! neuron fate commitment GO:0048663 52 28 0,000 0,01331077 0,01789664 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 0,000 0,01331077 0,0178868 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,01331077 0,01787696 ! protein amino acid acylation GO:0043543 59 28 0,000 0,01331077 0,01786714 ! vesicle docking GO:0048278 55 28 0,000 0,01331077 0,01785733 ! circadian rhythm GO:0007623 56 28 0,000 0,01331077 0,01784753 ! dendrite development GO:0016358 67 28 0,000 0,01331077 0,01783774 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,01331077 0,01782796 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,01331077 0,01781819 ! sperm motility GO:0030317 37 28 0,000 0,01331077 0,01780843 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,01331077 0,01779869 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,01331077 0,01778895 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,01331077 0,01777922 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,01331077 0,01776951 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,01331077 0,0177598 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,01331077 0,01775011 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,01331077 0,01774043 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,01331077 0,01773075 ! glutathione metabolic process GO:0006749 42 28 0,000 0,01331077 0,01772109 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,01331077 0,01771144 ! lipid oxidation GO:0034440 48 28 0,000 0,01331077 0,0177018 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,01331077 0,01769216 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,01331077 0,01768254 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,01378305 0,0183 ! translational initiation GO:0006413 66 29 0,000 0,01378305 0,01829006 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,01378305 0,01828013 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,01378305 0,01827021 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,01378305 0,0182603 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,01378305 0,0182504 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,01378305 0,01824052 ! primary neural tube formation GO:0014020 61 29 0,000 0,01378305 0,01823064 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,01378305 0,01822078 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,01378305 0,01821092 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,01378305 0,01820108 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,01378305 0,01819124 ! somitogenesis GO:0001756 52 29 0,000 0,01378305 0,01818142 ! synaptogenesis GO:0007416 46 29 0,000 0,01378305 0,01817161 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,01378305 0,01816181 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,01378305 0,01815202 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,01378305 0,01814224 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,01378305 0,01813247 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,01425512 0,01874342 ! phenol metabolic process GO:0018958 56 30 0,000 0,01425512 0,01873333 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,01425512 0,01872326 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,01425512 0,0187132 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,01425512 0,01870315 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,01425512 0,01869311 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,01425512 0,01868308 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,01425512 0,01867307 ! acute-phase response GO:0006953 50 30 0,000 0,01425512 0,01866306 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,01425512 0,01865306 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,01425512 0,01864308 ! myofibril assembly GO:0030239 50 30 0,000 0,01425512 0,0186331 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,01425512 0,01862314 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,01425512 0,01861319 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,01425512 0,01860324 ! cell fate determination GO:0001709 64 30 0,000 0,01425512 0,01859331 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,01425512 0,01858339 ! phospholipid transport GO:0015914 65 30 0,000 0,01425512 0,01857348 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,01425512 0,01856358 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,01425512 0,01855369 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,01425512 0,01854381 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,01425512 0,01853394 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,01425512 0,01852408 GO:0048871|multicellular organismal homeostasis, ! regulation of B cell activation GO:0050864 55 30 0,000 0,01425512 0,01851423 ! regulation of coagulation GO:0050818 52 30 0,000 0,01425512 0,01850439 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,01472699 0,01910676 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,01472699 0,01909662 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,01472699 0,01908649 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,01472699 0,01907637 ! cell junction assembly GO:0034329 85 31 0,000 0,01472699 0,01906626 ! regulation of innate immune response GO:0045088 57 31 0,000 0,01472699 0,01905616 ! ovulation cycle process GO:0022602 55 31 0,000 0,01472699 0,01904607 ! peptide transport GO:0015833 60 31 0,000 0,01472699 0,01903599 ! male gonad development GO:0008584 56 31 0,000 0,01472699 0,01902593 ! iron ion homeostasis GO:0055072 60 31 0,000 0,01472699 0,01901587 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,01472699 0,01900582 ! detection of light stimulus GO:0009583 44 31 0,000 0,01472699 0,01899579 ! cellular response to extracellular stimulus GO:0031668 52 31 0,000 0,01472699 0,01898577 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,01472699 0,01897575 ! natural killer cell activation GO:0030101 50 31 0,000 0,01472699 0,01896575 ! ensheathment of neurons GO:0007272 64 31 0,000 0,01472699 0,01895576 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,01472699 0,01894577 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,01472699 0,0189358 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,01472699 0,01892584 ! eye morphogenesis GO:0048592 65 31 0,000 0,01472699 0,01891589 ! response to heat GO:0009408 54 31 0,000 0,01472699 0,01890595 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,01472699 0,01889602 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,01519863 0,01949095 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,01519863 0,01948073 ! collagen metabolic process GO:0032963 49 32 0,000 0,01519863 0,01947051 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,01519863 0,0194603 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,01519863 0,01945011 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,01519863 0,01943993 ! metanephros development GO:0001656 81 32 0,000 0,01519863 0,01942976 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,01519863 0,01941959 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,01519863 0,01940944 ! muscle cell development GO:0055001 52 32 0,000 0,01519863 0,0193993 ! mesoderm formation GO:0001707 73 32 0,000 0,01519863 0,01938917 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,01519863 0,01937905 ! ovulation cycle GO:0042698 57 32 0,000 0,01519863 0,01936894 ! peripheral nervous system development GO:0007422 68 32 0,000 0,01519863 0,01935884 ! BMP signaling pathway GO:0030509 71 32 0,000 0,01519863 0,01934876 ! hindbrain development GO:0030902 65 32 0,000 0,01519863 0,01933868 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,01519863 0,01932861 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,01519863 0,01931855 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,01519863 0,01930851 ! gene silencing GO:0016458 71 32 0,000 0,01519863 0,01929847 ! regulation of pH GO:0006885 56 33 0,000 0,01567007 0,01988674 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,01567007 0,01987642 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,01567007 0,0198661 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,01567007 0,0198558 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,01567007 0,01984551 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,01567007 0,01983522 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,01567007 0,01982495 ! response to ionizing radiation GO:0010212 74 33 0,000 0,01567007 0,01981469 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,01567007 0,01980444 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,01567007 0,0197942 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,01567007 0,01978397 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,01567007 0,01977375 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,01567007 0,01976354 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,01567007 0,01975334 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,01567007 0,01974316 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,01614129 0,02032638 ! glial cell differentiation GO:0010001 67 34 0,000 0,01614129 0,02031591 ! post-embryonic development GO:0009791 76 34 0,000 0,01614129 0,02030545 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,01614129 0,020295 ! cholesterol transport GO:0030301 62 34 0,000 0,01614129 0,02028456 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,01614129 0,02027413 ! spliceosome assembly GO:0000245 75 34 0,000 0,01614129 0,02026371 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,01614129 0,0202533 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,01614129 0,0202429 ! formation of primary germ layer GO:0001704 76 34 0,000 0,01614129 0,02023252 ! cell fate specification GO:0001708 56 34 0,000 0,01614129 0,02022214 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,01614129 0,02021178 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,01614129 0,02020142 ! adult locomotory behavior GO:0008344 62 34 0,000 0,01614129 0,02019108 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,01614129 0,02018075 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,0166123 0,02075901 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,0166123 0,02074839 ! negative regulation of secretion GO:0051048 68 35 0,000 0,0166123 0,02073779 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,0166123 0,0207272 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,0166123 0,02071662 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,0166123 0,02070605 ! membrane docking GO:0022406 69 35 0,000 0,0166123 0,02069549 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,0166123 0,02068494 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,0166123 0,02067441 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,0166123 0,02066388 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,0166123 0,02065336 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,0166123 0,02064286 ! ceramide metabolic process GO:0006672 72 35 0,000 0,0166123 0,02063236 ! telencephalon development GO:0021537 81 35 0,000 0,0166123 0,02062188 ! sterol transport GO:0015918 63 35 0,000 0,0166123 0,02061141 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,0166123 0,02060094 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,0166123 0,02059049 ! placenta development GO:0001890 53 35 0,000 0,0166123 0,02058005 ! vesicle localization GO:0051648 70 35 0,000 0,0166123 0,02056962 ! regulation of muscle development GO:0048634 82 36 0,000 0,0170831 0,02114185 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,0170831 0,02113115 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,0170831 0,02112045 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,0170831 0,02110977 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,0170831 0,0210991 ! positive regulation of cell development GO:0010720 85 36 0,000 0,0170831 0,02108844 ! protein targeting to membrane GO:0006612 75 36 0,000 0,0170831 0,02107779 ! regulation of proteolysis GO:0030162 77 36 0,000 0,0170831 0,02106715 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,0170831 0,02105652 ! aerobic respiration GO:0009060 56 36 0,000 0,0170831 0,0210459 ! cytokine production GO:0001816 68 36 0,000 0,0170831 0,02103529 ! embryonic organ development GO:0048568 67 36 0,000 0,0170831 0,02102469 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,0170831 0,02101411 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,0170831 0,02100353 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,01755369 0,02157126 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,01755369 0,02156041 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,01755369 0,02154958 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,01755369 0,02153876 ! odontogenesis GO:0042476 74 37 0,000 0,01755369 0,02152794 ! actomyosin structure organization GO:0031032 68 37 0,000 0,01755369 0,02151714 ! cell junction organization GO:0034330 96 37 0,000 0,01755369 0,02150635 ! tissue remodeling GO:0048771 78 37 0,000 0,01755369 0,02149557 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,01755369 0,0214848 ! female gonad development GO:0008585 71 37 0,000 0,01755369 0,02147404 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,01755369 0,02146329 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,01755369 0,02145256 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,01755369 0,02144183 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,01755369 0,02143112 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,01802406 0,0219944 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,01802406 0,02198342 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,01802406 0,02197245 ! organic anion transport GO:0015711 82 38 0,000 0,01802406 0,02196149 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,01802406 0,02195054 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,01802406 0,0219396 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,01802406 0,02192868 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,01802406 0,02191776 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,01802406 0,02190686 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,01802406 0,02189597 ! regulation of protein stability GO:0031647 77 38 0,000 0,01802406 0,02188508 ! spermatid development GO:0007286 69 38 0,000 0,01802406 0,02187421 ! glycogen metabolic process GO:0005977 63 38 0,000 0,01802406 0,02186335 ! pigment metabolic process GO:0042440 87 38 0,000 0,01802406 0,0218525 ! cellular response to insulin stimulus GO:0032869 85 38 0,000 0,01802406 0,02184166 ! neural tube formation GO:0001841 79 38 0,000 0,01802406 0,02183083 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,01849423 0,02238919 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,01849423 0,0223781 ! negative regulation of binding GO:0051100 71 39 0,000 0,01849423 0,02236703 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,01849423 0,02235596 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,01849423 0,0223449 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,01849423 0,02233386 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,01849423 0,02232282 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,01849423 0,0223118 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,01849423 0,02230079 ! positive regulation of leukocyte proliferation GO:0070665 70 39 0,000 0,01849423 0,02228978 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,01849423 0,02227879 ! glucan metabolic process GO:0044042 64 39 0,000 0,01849423 0,02226781 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,01896418 0,02282241 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 0,000 0,01896418 0,02281117 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,01896418 0,02279994 ! learning GO:0007612 82 40 0,000 0,01896418 0,02278873 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,01896418 0,02277752 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 75 40 0,000 0,01896418 0,02276633 ! mismatch repair GO:0006298 58 40 0,000 0,01896418 0,02275515 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,01896418 0,02274398 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,01896418 0,02273282 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,01896418 0,02272167 ! RNA export from nucleus GO:0006405 61 41 0,000 0,01943392 0,02327307 ! mRNA catabolic process GO:0006402 79 41 0,000 0,01943392 0,02326166 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,01943392 0,02325027 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,01943392 0,02323889 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,01943392 0,02322752 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,01943392 0,02321616 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,01943392 0,02320482 ! gliogenesis GO:0042063 91 41 0,000 0,01943392 0,02319348 ! feeding behavior GO:0007631 69 41 0,000 0,01943392 0,02318216 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,01943392 0,02317084 ! mesenchymal cell development GO:0014031 94 41 0,000 0,01943392 0,02315954 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,01943392 0,02314825 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,01943392 0,02313697 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,01943392 0,0231257 ! spermatid differentiation GO:0048515 73 41 0,000 0,01943392 0,02311444 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,01943392 0,02310319 ! RNA modification GO:0009451 64 41 0,000 0,01943392 0,02309195 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,01990344 0,02363836 ! ear morphogenesis GO:0042471 64 42 0,000 0,01990344 0,02362688 ! organic ether metabolic process GO:0018904 59 42 0,000 0,01990344 0,0236154 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,01990344 0,02360394 ! regulation of intracellular protein transport GO:0033157 86 42 0,000 0,01990344 0,02359248 ! T cell differentiation GO:0030217 93 42 0,000 0,01990344 0,02358104 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,01990344 0,02356961 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,01990344 0,02355819 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,01990344 0,02354678 ! regulation of protein secretion GO:0050708 77 42 0,000 0,01990344 0,02353539 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,01990344 0,023524 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,01990344 0,02351263 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,02037276 0,02405541 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 0,000 0,02037276 0,02404379 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,02037276 0,02403218 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,02037276 0,02402058 ! regulation of tube size GO:0035150 76 43 0,000 0,02037276 0,024009 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,02037276 0,02399742 ! glucose transport GO:0015758 66 43 0,000 0,02037276 0,02398585 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,02037276 0,0239743 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,02037276 0,02396276 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,02037276 0,02395123 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,02037276 0,02393971 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,02037276 0,0239282 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,02037276 0,0239167 ! segmentation GO:0035282 78 43 0,000 0,02037276 0,02390521 ! ion transmembrane transport GO:0034220 79 43 0,000 0,02037276 0,02389373 ! neuron migration GO:0001764 85 43 0,000 0,02037276 0,02388227 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,02037276 0,02387081 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,02084186 0,02440876 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,02084186 0,02439706 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,02084186 0,02438538 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,02084186 0,0243737 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,02084186 0,02436204 ! hexose transport GO:0008645 68 44 0,000 0,02084186 0,02435039 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,02084186 0,02433875 ! striated muscle contraction GO:0006941 85 44 0,000 0,02084186 0,02432712 ! phagocytosis GO:0006909 105 44 0,000 0,02084186 0,02431551 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,02084186 0,0243039 ! double-strand break repair GO:0006302 85 44 0,000 0,02084186 0,0242923 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,02131075 0,02482698 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,02131075 0,02481514 ! regulation of epithelial cell proliferation GO:0050678 122 45 0,000 0,02131075 0,02480332 ! induction of apoptosis by intracellular signals GO:0008629 95 45 0,000 0,02131075 0,02479151 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,02131075 0,02477971 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,02131075 0,02476792 ! biopolymer methylation GO:0043414 91 45 0,000 0,02131075 0,02475615 ! B cell differentiation GO:0030183 124 45 0,000 0,02131075 0,02474438 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,02131075 0,02473262 ! female gamete generation GO:0007292 71 45 0,000 0,02131075 0,02472088 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,02131075 0,02470915 ! polyol metabolic process GO:0019751 77 45 0,000 0,02131075 0,02469743 ! developmental growth GO:0048589 88 45 0,000 0,02131075 0,02468572 ! maintenance of location in cell GO:0051651 101 45 0,000 0,02131075 0,02467402 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,02177944 0,02520472 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,02177944 0,02519279 ! glycolysis GO:0006096 71 46 0,000 0,02177944 0,02518086 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 0,000 0,02177944 0,02516895 ! regulation of gene-specific transcription GO:0032583 102 46 0,000 0,02177944 0,02515705 ! leukocyte migration GO:0050900 75 46 0,000 0,02177944 0,02514516 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,02177944 0,02513328 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,02177944 0,02512142 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,02177944 0,02510956 ! pigmentation GO:0043473 103 46 0,000 0,02177944 0,02509772 ! cell growth GO:0016049 90 46 0,000 0,02177944 0,02508589 ! positive regulation of protein transport GO:0051222 80 46 0,000 0,02177944 0,02507406 ! neural tube development GO:0021915 91 47 0,000 0,02224791 0,02560134 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,02224791 0,02558928 ! response to insulin stimulus GO:0032868 98 47 0,000 0,02224791 0,02557724 ! positive regulation of defense response GO:0031349 88 48 0,000 0,02271616 0,02610329 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,02271616 0,02609102 ! mitochondrial transport GO:0006839 94 48 0,000 0,02271616 0,02607876 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,02271616 0,02606651 ! cellular component disassembly GO:0022411 89 48 0,000 0,02271616 0,02605427 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,02271616 0,02604204 ! endosome transport GO:0016197 127 48 0,000 0,02271616 0,02602983 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,02271616 0,02601762 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,02271616 0,02600543 ! male sex differentiation GO:0046661 93 48 0,000 0,02271616 0,02599325 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,02271616 0,02598108 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,02271616 0,02596892 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,02271616 0,02595678 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,02271616 0,02594464 ! methylation GO:0032259 97 48 0,000 0,02271616 0,02593252 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,02318421 0,02645448 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,02318421 0,02644212 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,02318421 0,02642979 ! JNK cascade GO:0007254 106 49 0,000 0,02318421 0,02641746 ! regulation of mast cell proliferation GO:0070666 89 49 0,000 0,02318421 0,02640514 ! protein homooligomerization GO:0051260 84 49 0,000 0,02318421 0,02639284 ! regulation of action potential GO:0001508 102 50 0,000 0,02365205 0,02691288 ! regulation of ion transport GO:0043269 86 50 0,000 0,02365205 0,02690035 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,02365205 0,02688783 ! endocrine system development GO:0035270 109 50 0,000 0,02365205 0,02687533 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,02365205 0,02686283 ! activation of caspase activity GO:0006919 95 50 0,000 0,02365205 0,02685035 ! regulation of ossification GO:0030278 123 50 0,000 0,02365205 0,02683788 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,02365205 0,02682542 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,02365205 0,02681297 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,02365205 0,02680054 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,02365205 0,02678811 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,02365205 0,0267757 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,02411968 0,02729244 ! viral infectious cycle GO:0019058 104 51 0,000 0,02411968 0,0272798 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,02411968 0,02726718 ! peptide metabolic process GO:0006518 80 51 0,000 0,02411968 0,02725456 ! response to temperature stimulus GO:0009266 84 51 0,000 0,02411968 0,02724196 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,02411968 0,02722937 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,02411968 0,0272168 ! positive regulation of binding GO:0051099 88 52 0,000 0,02458709 0,02773142 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,02458709 0,02771863 ! Notch signaling pathway GO:0007219 111 52 0,000 0,02458709 0,02770584 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,02458709 0,02769307 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,02458709 0,02768031 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,02458709 0,02766756 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,02458709 0,02765482 ! excretion GO:0007588 87 52 0,000 0,02458709 0,02764209 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,02458709 0,02762938 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,02458709 0,02761667 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,02458709 0,02760398 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,02458709 0,0275913 ! amino acid activation GO:0043038 98 52 0,000 0,02458709 0,02757863 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,0250543 0,02808979 ! positive regulation of growth GO:0045927 96 53 0,000 0,0250543 0,0280769 ! inner ear development GO:0048839 89 53 0,000 0,0250543 0,02806403 ! chromatin remodeling GO:0006338 122 53 0,000 0,0250543 0,02805117 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,0250543 0,02803832 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,0250543 0,02802548 ! vesicle organization GO:0016050 127 53 0,000 0,0250543 0,02801265 ! regulation of leukocyte proliferation GO:0070663 97 53 0,000 0,0250543 0,02799984 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,0250543 0,02798703 ! cartilage development GO:0051216 99 53 0,000 0,0250543 0,02797424 ! synapse organization GO:0050808 102 53 0,000 0,0250543 0,02796146 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,02552129 0,02846964 ! regulation of translational initiation GO:0006446 87 54 0,000 0,02552129 0,02845664 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,02552129 0,02844366 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,02552129 0,02843069 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 0,000 0,02552129 0,02841773 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,02552129 0,02840479 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,02552129 0,02839185 ! membrane fusion GO:0006944 122 54 0,000 0,02552129 0,02837893 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,02552129 0,02836602 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,02552129 0,02835312 ! regulation of cell shape GO:0008360 142 54 0,000 0,02552129 0,02834023 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,02552129 0,02832736 ! RNA catabolic process GO:0006401 103 55 0,000 0,02598807 0,02883236 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,02598807 0,02881927 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,02598807 0,0288062 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,02598807 0,02879313 ! cell recognition GO:0008037 98 55 0,000 0,02598807 0,02878008 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,02598807 0,02876704 ! cell maturation GO:0048469 107 55 0,000 0,02598807 0,02875401 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,02598807 0,028741 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,02598807 0,02872799 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,02645464 0,02923053 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,02645464 0,02921731 ! glucose catabolic process GO:0006007 88 56 0,000 0,02645464 0,02920411 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,02645464 0,02919092 ! RNA elongation GO:0006354 90 56 0,000 0,02645464 0,02917774 ! chloride transport GO:0006821 102 57 0,000 0,02692101 0,02967871 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,02692101 0,02966532 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,02692101 0,02965195 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 131 57 0,000 0,02692101 0,02963859 ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,02692101 0,02962523 ! heart morphogenesis GO:0003007 105 57 0,000 0,02692101 0,0296119 ! regulation of intracellular transport GO:0032386 108 57 0,000 0,02692101 0,02959857 ! regulation of actin filament length GO:0030832 118 58 0,000 0,02738716 0,03009754 ! positive regulation of cell migration GO:0030335 137 58 0,000 0,02738716 0,03008401 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,02738716 0,03007049 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,02738716 0,03005698 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,02738716 0,03004348 ! aging GO:0007568 112 58 0,000 0,02738716 0,03003 ! gastrulation GO:0007369 122 58 0,000 0,02738716 0,03001652 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,02738716 0,03000306 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,02738716 0,02998961 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,02738716 0,02997618 ! maintenance of location GO:0051235 124 58 0,000 0,02738716 0,02996275 ! nuclear export GO:0051168 110 59 0,000 0,0278531 0,03045888 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,02831883 0,03095432 ! lipid modification GO:0030258 112 60 0,000 0,02831883 0,03094048 ! DNA catabolic process GO:0006308 94 60 0,000 0,02831883 0,03092665 ! regulation of endocytosis GO:0030100 104 60 0,000 0,02831883 0,03091283 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,02831883 0,03089902 ! adult behavior GO:0030534 104 60 0,000 0,02831883 0,03088523 ! kidney development GO:0001822 133 60 0,000 0,02831883 0,03087145 ! positive regulation of secretion GO:0051047 110 61 0,000 0,02878436 0,03136493 ! regulation of cellular component size GO:0032535 125 61 0,000 0,02878436 0,03135095 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,02878436 0,03133698 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,02878436 0,03132302 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,02878436 0,03130907 ! regulation of heart contraction GO:0008016 123 61 0,000 0,02878436 0,03129514 ! camera-type eye development GO:0043010 126 61 0,000 0,02878436 0,03128122 ! proton transport GO:0015992 117 61 0,000 0,02878436 0,03126731 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,02878436 0,03125341 ! viral reproductive process GO:0022415 132 62 0,000 0,02924967 0,03174453 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,02924967 0,03173043 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,02924967 0,03171635 ! tRNA processing GO:0008033 102 62 0,000 0,02924967 0,03170228 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,02924967 0,03168822 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,02971477 0,03217783 ! mesoderm development GO:0007498 128 63 0,000 0,02971477 0,03216357 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,02971477 0,03214933 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,02971477 0,0321351 ! hydrogen transport GO:0006818 121 64 0,000 0,03017966 0,03262341 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,03017966 0,03260898 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,03017966 0,03259457 ! protein amino acid autophosphorylation GO:0046777 157 64 0,000 0,03017966 0,03258017 ! response to peptide hormone stimulus GO:0043434 129 64 0,000 0,03017966 0,03256577 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,03064434 0,0330526 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,03064434 0,03303801 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,03064434 0,03302344 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,03064434 0,03300888 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,03064434 0,03299433 ! positive regulation of cell motion GO:0051272 157 65 0,000 0,03064434 0,03297979 ! ear development GO:0043583 114 66 0,000 0,03110882 0,03346492 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,03110882 0,03345019 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,03110882 0,03343548 ! gonad development GO:0008406 115 66 0,000 0,03110882 0,03342078 ! steroid hormone receptor signaling pathway GO:0030518 146 66 0,000 0,03110882 0,03340608 ! negative regulation of cell growth GO:0030308 142 67 0,000 0,03157308 0,03388974 ! activation of MAPK activity GO:0000187 124 67 0,000 0,03157308 0,03387485 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,03157308 0,03385998 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,03157308 0,03384512 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,03157308 0,03383028 ! secondary metabolic process GO:0019748 125 67 0,000 0,03157308 0,03381545 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,03157308 0,03380063 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,03203714 0,0342824 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,03203714 0,03426739 ! hexose catabolic process GO:0019320 113 68 0,000 0,03203714 0,0342524 ! extracellular matrix organization GO:0030198 146 68 0,000 0,03203714 0,03423741 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,03203714 0,03422244 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,03203714 0,03420748 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,03203714 0,03419254 ! viral reproduction GO:0016032 142 68 0,000 0,03203714 0,03417761 ! regulation of lipase activity GO:0060191 137 68 0,000 0,03203714 0,03416269 ! adaptive immune response GO:0002250 126 68 0,000 0,03203714 0,03414779 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cell projection assembly GO:0030031 138 68 0,000 0,03203714 0,03413289 ! negative regulation of cell size GO:0045792 144 69 0,000 0,03250098 0,03461199 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,03250098 0,03459691 ! negative regulation of protein kinase activity GO:0006469 144 69 0,000 0,03250098 0,03458184 ! lung development GO:0030324 165 69 0,000 0,03250098 0,03456678 ! urogenital system development GO:0001655 149 69 0,000 0,03250098 0,03455174 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,03250098 0,03453671 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 0,000 0,03250098 0,03452169 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,03250098 0,03450669 ! developmental maturation GO:0021700 128 69 0,000 0,03250098 0,0344917 ! single fertilization GO:0007338 83 69 0,000 0,03250098 0,03447672 ! negative regulation of kinase activity GO:0033673 145 70 0,000 0,03296462 0,03495337 ! cell redox homeostasis GO:0045454 114 70 0,000 0,03296462 0,0349382 ! germ cell development GO:0007281 133 70 0,000 0,03296462 0,03492305 ! activation of immune response GO:0002253 120 70 0,000 0,03296462 0,03490792 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,03296462 0,03489279 ! cell cycle checkpoint GO:0000075 145 71 0,000 0,03342804 0,035368 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,03342804 0,03535269 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,03342804 0,03533739 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 0,000 0,03342804 0,03532211 ! appendage morphogenesis GO:0035107 150 72 0,000 0,03389126 0,03579609 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,03389126 0,03578062 ! respiratory tube development GO:0030323 171 72 0,000 0,03389126 0,03576516 ! actin filament organization GO:0007015 167 72 0,000 0,03389126 0,03574972 ! B cell activation GO:0042113 179 72 0,000 0,03389126 0,03573429 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,03389126 0,03571888 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,03389126 0,03570347 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,03389126 0,03568808 ! appendage development GO:0048736 151 73 0,000 0,03435427 0,03616005 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,03435427 0,03614448 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,03435427 0,03612892 ! regulation of immune effector process GO:0002697 156 73 0,000 0,03435427 0,03611337 ! acute inflammatory response GO:0002526 118 74 0,000 0,03481707 0,03658413 ! amino acid transport GO:0006865 148 74 0,000 0,03481707 0,0365684 ! regulation of caspase activity GO:0043281 136 74 0,000 0,03481707 0,03655269 ! negative regulation of transferase activity GO:0051348 155 74 0,000 0,03481707 0,03653699 ! respiratory system development GO:0060541 175 74 0,000 0,03481707 0,0365213 ! regulation of transcription factor activity GO:0051090 137 75 0,000 0,03527966 0,03699065 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 143 75 0,000 0,03527966 0,03697478 ! reproductive structure development GO:0048608 131 75 0,000 0,03527966 0,03695893 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,03527966 0,03694308 ! eye development GO:0001654 155 75 0,000 0,03527966 0,03692726 ! axon guidance GO:0007411 162 75 0,000 0,03527966 0,03691144 ! rhythmic process GO:0048511 142 75 0,000 0,03527966 0,03689564 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,03574204 0,03736321 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,03574204 0,03734723 ! learning or memory GO:0007611 161 76 0,000 0,03574204 0,03733126 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,03574204 0,03731531 ! regulation of blood pressure GO:0008217 134 76 0,000 0,03574204 0,03729937 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,03574204 0,03728344 ! amine catabolic process GO:0009310 136 77 0,000 0,03620422 0,03774943 ! neurotransmitter transport GO:0006836 142 77 0,000 0,03620422 0,03773332 ! phosphoinositide metabolic process GO:0030384 146 77 0,000 0,03620422 0,03771723 ! regulation of endopeptidase activity GO:0052548 141 77 0,000 0,03620422 0,03770115 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,03620422 0,03768509 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,03620422 0,03766904 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,03620422 0,037653 ! regulation of catabolic process GO:0009894 173 77 0,000 0,03620422 0,03763698 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,03666618 0,03810102 ! antigen processing and presentation GO:0019882 117 78 0,000 0,03666618 0,03808482 ! fertilization GO:0009566 99 78 0,000 0,03666618 0,03806863 ! positive regulation of lymphocyte activation GO:0051251 142 78 0,000 0,03666618 0,03805246 ! blood coagulation GO:0007596 151 79 0,000 0,03712794 0,03851531 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,03712794 0,03849896 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,03712794 0,03848263 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,03712794 0,03846631 ! protein oligomerization GO:0051259 149 79 0,000 0,03712794 0,03845 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,03712794 0,03843371 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,03758949 0,03889501 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,03758949 0,03887854 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,03758949 0,03886209 ! muscle cell differentiation GO:0042692 178 81 0,000 0,03805083 0,03932241 ! response to hypoxia GO:0001666 178 81 0,000 0,03805083 0,03930578 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,03805083 0,03928917 ! regulation of peptidase activity GO:0052547 150 82 0,000 0,03851196 0,03974851 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,03851196 0,03973172 ! protein import into nucleus GO:0006606 174 82 0,000 0,03851196 0,03971495 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,03897289 0,04017332 ! exocytosis GO:0006887 153 83 0,000 0,03897289 0,04015637 ! response to drug GO:0042493 149 83 0,000 0,03897289 0,04013944 ! response to oxygen levels GO:0070482 183 83 0,000 0,03897289 0,04012253 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,03897289 0,04010563 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,03897289 0,04008874 ! nuclear import GO:0051170 177 83 0,000 0,03897289 0,04007187 ! inorganic anion transport GO:0015698 156 83 0,000 0,03897289 0,04005501 ! T cell activation GO:0042110 189 84 0,000 0,0394336 0,04051148 ! response to nutrient GO:0007584 135 84 0,000 0,0394336 0,04049445 ! digestion GO:0007586 130 84 0,000 0,0394336 0,04047743 ! hemostasis GO:0007599 165 85 0,000 0,03989411 0,04093293 ! negative regulation of transport GO:0051051 164 85 0,000 0,03989411 0,04091575 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,03989411 0,04089858 ! negative regulation of growth GO:0045926 168 85 0,000 0,03989411 0,04088142 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,03989411 0,04086428 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,03989411 0,04084716 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,03989411 0,04083004 ! cellular response to hormone stimulus GO:0032870 182 85 0,000 0,03989411 0,04081295 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,04035441 0,04126657 ! regulation of lyase activity GO:0051339 169 86 0,000 0,04035441 0,0412493 ! positive regulation of cell activation GO:0050867 161 86 0,000 0,04035441 0,04123205 GO:0002696|positive regulation of leukocyte activation, ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,0408145 0,04168471 ! mitochondrion organization GO:0007005 159 87 0,000 0,0408145 0,04166729 ! alcohol catabolic process GO:0046164 142 87 0,000 0,0408145 0,04164989 ! nucleosome assembly GO:0006334 126 87 0,000 0,0408145 0,0416325 ! regulation of protein transport GO:0051223 165 87 0,000 0,0408145 0,04161512 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 143 88 0,000 0,04127439 0,04206647 ! amine biosynthetic process GO:0009309 146 88 0,000 0,04127439 0,04204893 ! sensory perception of smell GO:0007608 117 88 0,000 0,04127439 0,0420314 ! chromatin assembly GO:0031497 128 88 0,000 0,04127439 0,04201389 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,04127439 0,04199639 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,04173407 0,04244643 ! regulation of DNA binding GO:0051101 167 89 0,000 0,04173407 0,04242877 ! tube morphogenesis GO:0035239 194 89 0,000 0,04173407 0,04241112 ! cellular defense response GO:0006968 123 89 0,000 0,04173407 0,04239348 ! protein localization in nucleus GO:0034504 192 89 0,000 0,04173407 0,04237586 ! regulation of neurological system process GO:0031644 175 89 0,000 0,04173407 0,04235826 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,04219354 0,04280682 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,0426528 0,04325479 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! ossification GO:0001503 205 91 0,000 0,0426528 0,04323684 ! gland development GO:0048732 220 91 0,000 0,0426528 0,04321891 ! defense response to bacterium GO:0042742 112 91 0,000 0,0426528 0,04320099 ! bone development GO:0060348 206 92 0,000 0,04311186 0,04364785 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,04311186 0,04362977 ! regulation of cell adhesion GO:0030155 241 92 0,000 0,04311186 0,0436117 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,04357071 0,04405763 ! amine transport GO:0015837 181 93 0,000 0,04357071 0,0440394 ! positive regulation of MAP kinase activity GO:0043406 174 93 0,000 0,04357071 0,04402119 ! vitamin metabolic process GO:0006766 153 93 0,000 0,04357071 0,04400299 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,04402935 0,04444781 ! female pregnancy GO:0007565 166 94 0,000 0,04402935 0,04442945 ! sterol metabolic process GO:0016125 166 94 0,000 0,04402935 0,0444111 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,04402935 0,04439278 ! regulation of membrane potential GO:0042391 179 94 0,000 0,04402935 0,04437446 ! regulation of defense response GO:0031347 171 95 0,000 0,04448778 0,044818 ! nucleosome organization GO:0034728 143 95 0,000 0,04448778 0,04479953 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,04448778 0,04478107 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,04448778 0,04476262 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,04448778 0,0447442 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,04448778 0,04472578 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,04448778 0,04470738 ! sex differentiation GO:0007548 171 96 0,000 0,04494601 0,0451493 ! regulation of T cell activation GO:0050863 175 96 0,000 0,04494601 0,04513074 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,04540403 0,04557192 ! transcription initiation GO:0006352 171 97 0,000 0,04540403 0,0455532 ! regulation of protein localization GO:0032880 188 97 0,000 0,04540403 0,0455345 ! leukocyte differentiation GO:0002521 232 98 0,000 0,04586184 0,04597476 ! forebrain development GO:0030900 210 98 0,000 0,04586184 0,0459559 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,04586184 0,04593706 ! skeletal muscle tissue development GO:0007519 223 100 0,000 0,04677685 0,04683436 GO:0060538|skeletal muscle organ development, ! mRNA transport GO:0051028 185 100 0,000 0,04677685 0,04681518 ! positive regulation of immune response GO:0050778 175 100 0,000 0,04677685 0,04679601 ! hormone metabolic process GO:0042445 171 100 0,000 0,04677685 0,04677685