pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-b1/out-0.05-06-0.01-300-run-b1//th1-pval-1e-01-08-th2-pval-1e-02-02-th3-pval-1e-01-01-run-b1/go_data/7422-9-real-Sotiriou-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! spliceosome assembly GO:0000245 49 30 2,000 6,87E-06 0,01580027 ! negative regulation of bone resorption GO:0045779 10 5 1,000 1,508E-05 0,01734556 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 1,000 1,508E-05 0,01156371 ! ribonucleoprotein complex assembly GO:0022618 70 44 2,000 2,216E-05 0,01273914 ! mRNA stabilization GO:0048255 15 6 1,000 2,261E-05 0,0103994 GO:0043489|RNA stabilization, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 1,000 2,261E-05 8,666E-03 ! positive regulation of cell cycle GO:0045787 77 45 2,000 2,372E-05 7,793E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 3,163E-05 9,093E-03 ! T-helper 1 type immune response GO:0042088 11 7 1,000 3,163E-05 8,082E-03 ! induction of positive chemotaxis GO:0050930 14 8 1,000 4,214E-05 9,691E-03 ! positive regulation of endothelial cell migration GO:0010595 18 8 1,000 4,214E-05 8,81E-03 ! regulation of vascular permeability GO:0043114 12 8 1,000 4,214E-05 8,076E-03 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 1,000 4,214E-05 7,455E-03 ! lung alveolus development GO:0048286 17 9 1,000 5,413E-05 8,893E-03 ! blood vessel remodeling GO:0001974 21 10 1,000 6,762E-05 0,01036771 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 1,000 6,762E-05 9,72E-03 ! regulation of bone resorption GO:0045124 24 10 1,000 6,762E-05 9,148E-03 ! positive regulation of leukocyte migration GO:0002687 23 10 1,000 6,762E-05 8,64E-03 ! regulation of positive chemotaxis GO:0050926 17 11 1,000 8,258E-05 9,996E-03 GO:0050927|positive regulation of positive chemotaxis, ! positive regulation of endothelial cell proliferation GO:0001938 18 11 1,000 8,258E-05 9,496E-03 ! regulation of leukocyte migration GO:0002685 24 11 1,000 8,258E-05 9,044E-03 ! regulation of mRNA stability GO:0043488 27 12 1,000 9,902E-05 0,01035191 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 1,000 9,902E-05 9,902E-03 ! response to inorganic substance GO:0010035 115 75 2,000 1,101E-04 0,01055503 ! regulation of RNA stability GO:0043487 28 13 1,000 1,169E-04 0,01075778 ! negative regulation of bone remodeling GO:0046851 26 14 1,000 1,363E-04 0,01205882 ! response to cAMP GO:0051591 19 14 1,000 1,363E-04 0,0116122 ! epidermis morphogenesis GO:0048730 29 14 1,000 1,363E-04 0,01119748 ! mRNA splice site selection GO:0006376 26 14 1,000 1,363E-04 0,01081136 ! negative regulation of cell cycle process GO:0010948 24 15 1,000 1,572E-04 0,01204963 ! skin development GO:0043588 25 15 1,000 1,572E-04 0,01166093 ! negative regulation of tissue remodeling GO:0034104 27 15 1,000 1,572E-04 0,01129653 ! biomineral formation GO:0031214 18 15 1,000 1,572E-04 0,01095421 ! cellular response to unfolded protein GO:0034620 19 16 1,000 1,795E-04 0,01214162 GO:0030968|endoplasmic reticulum unfolded protein response, ! negative regulation of homeostatic process GO:0032845 28 17 1,000 2,033E-04 0,01335716 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 1,000 2,285E-04 0,01459826 ! in utero embryonic development GO:0001701 147 96 2,000 2,291E-04 0,01424109 ! regulation of endothelial cell migration GO:0010594 40 19 1,000 2,552E-04 0,0154452 ! positive regulation of locomotion GO:0040017 35 20 1,000 2,833E-04 0,01670856 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 1,000 2,833E-04 0,01629084 ! regulation of chemotaxis GO:0050920 36 21 1,000 3,129E-04 0,01755312 ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 3,129E-04 0,01713519 ! spliceosomal snRNP biogenesis GO:0000387 28 22 1,000 3,439E-04 0,01839634 ! vasculogenesis GO:0001570 33 22 1,000 3,439E-04 0,01797824 ! regulation of behavior GO:0050795 38 22 1,000 3,439E-04 0,01757872 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 3,764E-04 0,01881999 ! response to corticosteroid stimulus GO:0031960 36 23 1,000 3,764E-04 0,01841957 ! regulation of endothelial cell proliferation GO:0001936 46 24 1,000 4,103E-04 0,01966046 ! fat cell differentiation GO:0045444 37 24 1,000 4,103E-04 0,01925922 ! regulation of chromosome organization GO:0033044 35 25 1,000 4,456E-04 0,02049963 ! positive regulation of nuclear division GO:0051785 39 25 1,000 4,456E-04 0,02009767 GO:0045840|positive regulation of mitosis, ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 1,000 4,824E-04 0,02133751 ! response to hydrogen peroxide GO:0042542 42 29 1,000 6,013E-04 0,02609282 ! collagen metabolic process GO:0032963 40 30 1,000 6,437E-04 0,02741798 ! spindle organization GO:0007051 37 30 1,000 6,437E-04 0,02691947 ! odontogenesis GO:0042476 50 31 1,000 6,876E-04 0,0282406 ! response to mechanical stimulus GO:0009612 43 31 1,000 6,876E-04 0,02774515 ! mitotic sister chromatid segregation GO:0000070 45 32 1,000 7,329E-04 0,02906242 ! meiosis I GO:0007127 52 32 1,000 7,329E-04 0,02856984 ! sister chromatid segregation GO:0000819 46 33 1,000 7,796E-04 0,0298834 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 1,000 7,796E-04 0,0293935 ! cytokinesis GO:0000910 52 33 1,000 7,796E-04 0,02891942 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 1,000 8,277E-04 0,03021612 ! response to reactive oxygen species GO:0000302 55 36 1,000 9,28E-04 0,0333515 ! tissue remodeling GO:0048771 62 36 1,000 9,28E-04 0,0328384 ! multicellular organismal metabolic process GO:0044236 50 39 1,000 1,089E-03 0,03795218 ! response to calcium ion GO:0051592 58 40 1,000 1,146E-03 0,03932344 ! positive regulation of response to external stimulus GO:0032103 65 40 1,000 1,146E-03 0,03874515 ! embryonic skeletal system development GO:0048706 56 42 1,000 1,263E-03 0,04208471 ! regulation of cell shape GO:0008360 78 42 1,000 1,263E-03 0,0414835 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 1,000 1,323E-03 0,04286166 ! vascular process in circulatory system GO:0003018 69 45 1,000 1,448E-03 0,04626802 ! response to UV GO:0009411 75 46 1,000 1,513E-03 0,04767219 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 1,000 1,857E-03 0,05771293 ! positive regulation of cell migration GO:0030335 92 51 1,000 1,857E-03 0,05694343 ! positive regulation of organelle organization GO:0010638 82 51 1,000 1,857E-03 0,05619417 ! establishment of organelle localization GO:0051656 85 52 1,000 1,93E-03 0,05763907 ! regulation of bone remodeling GO:0046850 90 53 1,000 2,004E-03 0,0590865 ! regulation of mitosis GO:0007088 84 54 1,000 2,079E-03 0,06053627 GO:0051783|regulation of nuclear division, ! regulation of tissue remodeling GO:0034103 91 54 1,000 2,079E-03 0,05977957 ! positive regulation of cell motion GO:0051272 99 56 1,000 2,234E-03 0,06344215 ! chromosome segregation GO:0007059 83 57 1,000 2,314E-03 0,06489792 ! response to peptide hormone stimulus GO:0043434 84 57 1,000 2,314E-03 0,06411602 ! lung development GO:0030324 94 59 1,000 2,477E-03 0,06781436 ! regulation of homeostatic process GO:0032844 105 60 1,000 2,56E-03 0,06927474 ! meiosis GO:0007126 96 61 1,000 2,645E-03 0,07073638 GO:0051327|M phase of meiotic cell cycle, ! extracellular matrix organization GO:0030198 103 61 1,000 2,645E-03 0,06992332 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 1,000 2,645E-03 0,06912873 ! respiratory tube development GO:0030323 99 62 1,000 2,731E-03 0,0705767 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 1,000 2,731E-03 0,06979251 ! meiotic cell cycle GO:0051321 97 62 1,000 2,731E-03 0,06902556 ! organelle localization GO:0051640 96 62 1,000 2,731E-03 0,06827529 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 1,000 2,907E-03 0,07189634 ! respiratory system development GO:0060541 100 64 1,000 2,907E-03 0,07113148 ! adaptive immune response GO:0002250 94 64 1,000 2,907E-03 0,07038273 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 1,000 2,997E-03 0,07180604 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 1,000 2,997E-03 0,07106577 ! positive regulation of ligase activity GO:0051351 99 69 1,000 3,37E-03 0,07909514 ! response to metal ion GO:0010038 103 70 1,000 3,467E-03 0,08053777 ! positive regulation of phosphorylation GO:0042327 102 70 1,000 3,467E-03 0,07973239 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 1,000 3,564E-03 0,08116943 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 1,000 3,663E-03 0,08260722 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 132 72 1,000 3,663E-03 0,0818052 ! negative regulation of organelle organization GO:0010639 115 72 1,000 3,663E-03 0,08101862 ! response to steroid hormone stimulus GO:0048545 114 73 1,000 3,764E-03 0,08244479 ! response to oxygen levels GO:0070482 137 74 1,000 3,865E-03 0,08387176 ! response to nutrient GO:0007584 104 75 1,000 3,968E-03 0,08529943 ! regulation of ligase activity GO:0051340 114 75 1,000 3,968E-03 0,08450962 ! response to unfolded protein GO:0006986 99 76 1,000 4,072E-03 0,08593205 ! regulation of cell morphogenesis GO:0022604 140 76 1,000 4,072E-03 0,08515085 ! positive regulation of protein modification process GO:0031401 107 78 1,000 4,285E-03 0,08877875 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 1,000 4,502E-03 0,09244547 GO:0010498|proteasomal protein catabolic process, ! regulation of cell cycle process GO:0010564 122 81 1,000 4,612E-03 0,09387569 ! response to protein stimulus GO:0051789 111 81 1,000 4,612E-03 0,09305222 ! ossification GO:0001503 134 82 1,000 4,724E-03 0,09447733 GO:0060348|bone development, ! microtubule cytoskeleton organization GO:0000226 120 84 1,000 4,951E-03 0,09816712 ! negative regulation of multicellular organismal process GO:0051241 133 85 1,000 5,066E-03 0,09959765 ! interphase of mitotic cell cycle GO:0051329 156 86 1,000 5,183E-03 0,1010281 ! interphase GO:0051325 159 88 1,000 5,42E-03 0,10476157 ! response to oxidative stress GO:0006979 141 94 1,000 6,161E-03 0,11808581 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 6,277E-03 0,11931651 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 6,277E-03 0,1183385 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 6,277E-03 0,1173764 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 6,277E-03 0,11642982 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 6,277E-03 0,11549838 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 6,277E-03 0,11458173 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 6,277E-03 0,11367951 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 6,277E-03 0,11279139 ! sleep GO:0030431 11 5 0,000 6,277E-03 0,11191703 ! nucleotide-sugar transport GO:0015780 8 5 0,000 6,277E-03 0,11105613 ! regulation of interferon-beta production GO:0032648 5 5 0,000 6,277E-03 0,11020838 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 6,277E-03 0,10937347 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 6,277E-03 0,10855111 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 6,277E-03 0,10774103 ! tongue development GO:0043586 6 5 0,000 6,277E-03 0,10694294 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 6,277E-03 0,1061566 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 6,277E-03 0,10538173 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 6,277E-03 0,1046181 ! cobalt ion transport GO:0006824 9 5 0,000 6,277E-03 0,10386545 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 6,277E-03 0,10312355 ! SMAD protein complex assembly GO:0007183 9 5 0,000 6,277E-03 0,10239218 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 6,277E-03 0,10167111 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 6,277E-03 0,10096012 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 6,277E-03 0,10025901 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 6,277E-03 0,09956757 ! embryonic camera-type eye development GO:0031076 8 5 0,000 6,277E-03 0,0988856 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 6,277E-03 0,09821291 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 6,277E-03 0,09754931 ! adaptation of signaling pathway GO:0022401 7 5 0,000 6,277E-03 0,09689461 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 6,277E-03 0,09624865 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 6,277E-03 0,09561124 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 6,277E-03 0,09498222 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 6,277E-03 0,09436142 ! positive regulation of histone modification GO:0031058 5 5 0,000 6,277E-03 0,09374869 ! malate metabolic process GO:0006108 7 5 0,000 6,277E-03 0,09314385 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 6,277E-03 0,09254678 ! behavioral response to pain GO:0048266 7 5 0,000 6,277E-03 0,09195731 ! clathrin coat assembly GO:0048268 11 5 0,000 6,277E-03 0,0913753 ! phototransduction, visible light GO:0007603 6 5 0,000 6,277E-03 0,09080061 ! regulation of dopamine uptake GO:0051584 9 5 0,000 6,277E-03 0,09023311 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 6,277E-03 0,08967266 ! mating behavior GO:0007617 6 5 0,000 6,277E-03 0,08911912 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 6,277E-03 0,08857238 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 6,277E-03 0,0880323 ! rhythmic behavior GO:0007622 12 5 0,000 6,277E-03 0,08749877 ! copulation GO:0007620 7 5 0,000 6,277E-03 0,08697167 ! glial cell fate commitment GO:0021781 12 5 0,000 6,277E-03 0,08645088 ! protein maturation by protein folding GO:0022417 12 5 0,000 6,277E-03 0,08593629 ! embryonic hemopoiesis GO:0035162 10 5 0,000 6,277E-03 0,0854278 ! regulation of potassium ion transport GO:0043266 9 5 0,000 6,277E-03 0,08492528 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 6,277E-03 0,08442864 ! apoptotic cell clearance GO:0043277 13 5 0,000 6,277E-03 0,08393778 ! lipoprotein particle clearance GO:0034381 9 5 0,000 6,277E-03 0,08345259 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 6,277E-03 0,08297297 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 6,277E-03 0,08249884 ! response to protozoan GO:0001562 9 5 0,000 6,277E-03 0,0820301 ! positive regulation of glycolysis GO:0045821 11 5 0,000 6,277E-03 0,08156665 ! lymph vessel development GO:0001945 7 5 0,000 6,277E-03 0,08110841 ! endochondral ossification GO:0001958 12 5 0,000 6,277E-03 0,08065529 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 6,277E-03 0,08020721 ! parathyroid gland development GO:0060017 8 5 0,000 6,277E-03 0,07976407 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 6,277E-03 0,07932581 ! anagen GO:0042640 6 5 0,000 6,277E-03 0,07889234 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 6,277E-03 0,07846357 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 6,277E-03 0,07803945 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 6,277E-03 0,07761988 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 6,277E-03 0,0772048 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 6,277E-03 0,07679414 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 6,277E-03 0,07638782 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 6,277E-03 0,07598578 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 6,277E-03 0,07558795 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 6,277E-03 0,07519426 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 6,277E-03 0,07480465 ! cardiac muscle fiber development GO:0048739 7 5 0,000 6,277E-03 0,07441906 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 6,277E-03 0,07403742 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 6,277E-03 0,07365968 ! neutrophil mediated immunity GO:0002446 6 5 0,000 6,277E-03 0,07328577 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 6,277E-03 0,07291564 ! ovulation GO:0030728 6 5 0,000 6,277E-03 0,07254923 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 6,277E-03 0,07218649 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 6,277E-03 0,07182735 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 6,277E-03 0,07147177 ! response to pH GO:0009268 9 5 0,000 6,277E-03 0,07111969 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 6,277E-03 0,07077107 ! proline biosynthetic process GO:0006561 6 5 0,000 6,277E-03 0,07042584 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 6,277E-03 0,07008397 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 6,277E-03 0,0697454 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 6,277E-03 0,06941008 ! polyol catabolic process GO:0046174 7 5 0,000 6,277E-03 0,06907798 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 6,277E-03 0,06874904 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 6,277E-03 0,06842321 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 6,277E-03 0,06810046 ! sister chromatid cohesion GO:0007062 9 5 0,000 6,277E-03 0,06778074 ! nerve growth factor processing GO:0032455 7 5 0,000 6,277E-03 0,06746401 ! urea metabolic process GO:0019627 6 5 0,000 6,277E-03 0,06715022 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 6,277E-03 0,06683934 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 6,277E-03 0,06653132 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 6,277E-03 0,06622614 ! neutrophil activation GO:0042119 5 5 0,000 6,277E-03 0,06592373 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 6,277E-03 0,06562408 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 6,277E-03 0,06532714 ! response to food GO:0032094 5 5 0,000 6,277E-03 0,06503287 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 6,277E-03 0,06474124 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 6,277E-03 0,06445222 ! paraxial mesoderm development GO:0048339 9 5 0,000 6,277E-03 0,06416577 ! forebrain neuron development GO:0021884 7 5 0,000 6,277E-03 0,06388185 ! melanosome organization GO:0032438 7 5 0,000 6,277E-03 0,06360043 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 6,277E-03 0,06332148 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 6,277E-03 0,06304497 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 6,277E-03 0,06277086 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 6,277E-03 0,06249912 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 6,277E-03 0,06222973 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 6,277E-03 0,06196265 ! nucleoside transport GO:0015858 6 5 0,000 6,277E-03 0,06169785 ! nucleoside salvage GO:0043174 7 5 0,000 6,277E-03 0,06143531 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 6,277E-03 0,06117499 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 6,277E-03 0,06091687 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 6,277E-03 0,06066091 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 6,277E-03 0,0604071 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 6,277E-03 0,06015541 ! early endosome to late endosome transport GO:0045022 11 5 0,000 6,277E-03 0,0599058 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 6,277E-03 0,05965825 ! depyrimidination GO:0045008 8 5 0,000 6,277E-03 0,05941275 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 6,277E-03 0,05916925 ! 5S class rRNA transcription GO:0042791 8 5 0,000 6,277E-03 0,05892774 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 6,277E-03 0,0586882 ! regulation of centrosome cycle GO:0046605 7 5 0,000 6,277E-03 0,0584506 ! neuronal ion channel clustering GO:0045161 7 5 0,000 6,277E-03 0,05821491 ! sodium ion homeostasis GO:0055078 6 5 0,000 6,277E-03 0,05798111 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 6,277E-03 0,05774919 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 6,277E-03 0,05751911 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 6,277E-03 0,05729086 ! monocyte differentiation GO:0030224 8 5 0,000 6,277E-03 0,05706442 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 6,277E-03 0,05683975 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 6,277E-03 0,05661685 ! centrosome duplication GO:0051298 5 5 0,000 6,277E-03 0,05639569 ! response to UV-C GO:0010225 6 5 0,000 6,277E-03 0,05617625 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 6,277E-03 0,05595852 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 6,277E-03 0,05574246 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 6,277E-03 0,05552807 ! regulation of dendrite development GO:0050773 12 5 0,000 6,277E-03 0,05531532 ! peptidyl-arginine modification GO:0018195 7 5 0,000 6,277E-03 0,05510419 ! positive regulation of organ growth GO:0046622 6 5 0,000 6,277E-03 0,05489467 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 6,277E-03 0,05468673 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 6,277E-03 0,05448037 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 6,277E-03 0,05427555 ! regulation of dopamine secretion GO:0014059 12 5 0,000 6,277E-03 0,05407228 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 6,277E-03 0,05387051 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 6,277E-03 0,05367025 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 6,277E-03 0,05347147 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 6,277E-03 0,05327416 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 6,277E-03 0,0530783 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 6,277E-03 0,05288387 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 6,277E-03 0,05269087 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 6,277E-03 0,05249926 ! neural tube patterning GO:0021532 6 5 0,000 6,277E-03 0,05230905 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 6,277E-03 0,05212021 ! histone demethylation GO:0016577 9 5 0,000 6,277E-03 0,05193272 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 6,277E-03 0,05174659 ! regulation of sterol transport GO:0032371 7 5 0,000 6,277E-03 0,05156178 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 6,277E-03 0,05137828 ! enteric nervous system development GO:0048484 8 5 0,000 6,277E-03 0,05119609 ! establishment of planar polarity GO:0001736 6 5 0,000 6,277E-03 0,05101519 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 6,277E-03 0,05083555 ! muscle cell proliferation GO:0033002 8 5 0,000 6,277E-03 0,05065718 ! transcription termination GO:0006353 8 5 0,000 6,277E-03 0,05048006 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 6,277E-03 0,05030417 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 6,277E-03 0,05012951 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 6,277E-03 0,04995605 ! regulation of respiratory burst GO:0060263 8 5 0,000 6,277E-03 0,04978378 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 6,277E-03 0,04961271 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 6,277E-03 0,0494428 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 6,277E-03 0,04927405 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 6,277E-03 0,04910645 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 6,277E-03 0,04893999 ! apical protein localization GO:0045176 6 5 0,000 6,277E-03 0,04877465 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 6,277E-03 0,04861043 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 6,277E-03 0,04844731 ! galactolipid metabolic process GO:0019374 7 5 0,000 6,277E-03 0,04828528 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 6,277E-03 0,04812433 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 6,277E-03 0,04796444 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 6,277E-03 0,04780562 ! triglyceride catabolic process GO:0019433 6 5 0,000 6,277E-03 0,04764785 ! glial cell migration GO:0008347 10 5 0,000 6,277E-03 0,04749111 ! determination of adult lifespan GO:0008340 8 5 0,000 6,277E-03 0,0473354 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 6,277E-03 0,04718071 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 6,277E-03 0,04702703 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 6,277E-03 0,04687434 ! somatic stem cell maintenance GO:0035019 13 5 0,000 6,277E-03 0,04672265 ! cerebellar cortex formation GO:0021697 6 5 0,000 6,277E-03 0,04657193 ! neural plate development GO:0001840 6 5 0,000 6,277E-03 0,04642218 ! regulation of sensory perception GO:0051931 6 5 0,000 6,277E-03 0,04627339 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 6,277E-03 0,04612555 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 6,277E-03 0,04597865 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 6,277E-03 0,04583269 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 6,277E-03 0,04568765 ! sensory cilium assembly GO:0035058 6 5 0,000 6,277E-03 0,04554353 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 6,277E-03 0,04540031 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 6,277E-03 0,04525799 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 6,277E-03 0,04511655 ! spindle assembly GO:0051225 5 5 0,000 6,277E-03 0,044976 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 6,277E-03 0,04483633 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 6,277E-03 0,04469752 ! protein amino acid prenylation GO:0018346 9 5 0,000 6,277E-03 0,04455956 ! organ regeneration GO:0031100 7 5 0,000 6,277E-03 0,04442245 ! NAD biosynthetic process GO:0009435 7 5 0,000 6,277E-03 0,04428619 ! carnitine metabolic process GO:0009437 5 5 0,000 6,277E-03 0,04415076 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 6,277E-03 0,04401615 ! cellular anion homeostasis GO:0030002 6 5 0,000 6,277E-03 0,04388236 GO:0055081|anion homeostasis, ! angiogenesis GO:0001525 149 95 1,000 6,289E-03 0,04383045 ! regulation of response to external stimulus GO:0032101 139 96 1,000 6,418E-03 0,04459391 ! response to light stimulus GO:0009416 153 96 1,000 6,418E-03 0,04445959 ! extracellular structure organization GO:0043062 156 99 1,000 6,812E-03 0,04704751 ! tRNA transcription GO:0009304 11 6 0,000 7,528E-03 0,05183939 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 7,528E-03 0,05168465 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 7,528E-03 0,05153083 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 7,528E-03 0,05137792 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 7,528E-03 0,05122591 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 7,528E-03 0,0510748 ! regulation of helicase activity GO:0051095 11 6 0,000 7,528E-03 0,05092458 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 7,528E-03 0,05077524 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 7,528E-03 0,05062678 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 7,528E-03 0,05047918 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 7,528E-03 0,05033243 ! positive regulation of axon extension GO:0045773 8 6 0,000 7,528E-03 0,05018654 ! prostate gland development GO:0030850 9 6 0,000 7,528E-03 0,0500415 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 7,528E-03 0,04989728 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 7,528E-03 0,0497539 ! forebrain neuron differentiation GO:0021879 9 6 0,000 7,528E-03 0,04961134 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 7,528E-03 0,04946959 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 7,528E-03 0,04932865 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 7,528E-03 0,04918852 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 7,528E-03 0,04904917 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 7,528E-03 0,04891061 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 7,528E-03 0,04877284 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 7,528E-03 0,04863584 ! neuron adhesion GO:0007158 9 6 0,000 7,528E-03 0,0484996 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 7,528E-03 0,04836413 ! establishment of tissue polarity GO:0007164 7 6 0,000 7,528E-03 0,04822941 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 7,528E-03 0,04809544 ! signal peptide processing GO:0006465 8 6 0,000 7,528E-03 0,04796221 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 7,528E-03 0,04782972 ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 7,528E-03 0,04769795 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 7,528E-03 0,04756692 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 7,528E-03 0,0474366 ! opsonization GO:0008228 8 6 0,000 7,528E-03 0,04730699 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 7,528E-03 0,04717809 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 7,528E-03 0,04704988 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 7,528E-03 0,04692238 ! protein amino acid dealkylation GO:0008214 11 6 0,000 7,528E-03 0,04679556 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 7,528E-03 0,04666943 ! photoreceptor cell development GO:0042461 10 6 0,000 7,528E-03 0,04654397 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 7,528E-03 0,04641919 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 7,528E-03 0,04629507 ! mechanosensory behavior GO:0007638 8 6 0,000 7,528E-03 0,04617162 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 7,528E-03 0,04604882 ! negative regulation of endocytosis GO:0045806 8 6 0,000 7,528E-03 0,04592668 ! response to interferon-gamma GO:0034341 12 6 0,000 7,528E-03 0,04580518 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 7,528E-03 0,04568432 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 7,528E-03 0,0455641 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 7,528E-03 0,04544451 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 7,528E-03 0,04532554 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 7,528E-03 0,0452072 ! cGMP-mediated signaling GO:0019934 10 6 0,000 7,528E-03 0,04508947 ! activation of MAPKKK activity GO:0000185 10 6 0,000 7,528E-03 0,04497236 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 7,528E-03 0,04485585 ! thymic T cell selection GO:0045061 12 6 0,000 7,528E-03 0,04473994 ! protein lipoylation GO:0009249 10 6 0,000 7,528E-03 0,04462463 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 7,528E-03 0,04450992 ! pigment granule organization GO:0048753 11 6 0,000 7,528E-03 0,04439579 ! drug transport GO:0015893 6 6 0,000 7,528E-03 0,04428224 ! cysteine metabolic process GO:0006534 7 6 0,000 7,528E-03 0,04416928 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 7,528E-03 0,04405689 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 7,528E-03 0,04394507 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 7,528E-03 0,04383382 ! histidine metabolic process GO:0006547 6 6 0,000 7,528E-03 0,04372313 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 7,528E-03 0,04361299 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 7,528E-03 0,04350341 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 7,528E-03 0,04339438 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 7,528E-03 0,04328589 ! adenohypophysis development GO:0021984 10 6 0,000 7,528E-03 0,04317795 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 7,528E-03 0,04307054 ! hyperosmotic response GO:0006972 8 6 0,000 7,528E-03 0,04296367 ! microtubule nucleation GO:0007020 10 6 0,000 7,528E-03 0,04285732 ! ER overload response GO:0006983 7 6 0,000 7,528E-03 0,0427515 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 7,528E-03 0,0426462 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 7,528E-03 0,04254142 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 7,528E-03 0,04243715 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 7,528E-03 0,04233339 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 7,528E-03 0,04223014 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 7,528E-03 0,04212739 ! response to dietary excess GO:0002021 7 6 0,000 7,528E-03 0,04202514 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 7,528E-03 0,04192338 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 7,528E-03 0,04182212 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 7,528E-03 0,04172134 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 7,528E-03 0,04162105 ! glycerol ether catabolic process GO:0044269 8 6 0,000 7,528E-03 0,04152124 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 7,528E-03 0,04142191 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 7,528E-03 0,04132305 ! neuron apoptosis GO:0051402 8 6 0,000 7,528E-03 0,04122466 ! organic alcohol transport GO:0015850 9 6 0,000 7,528E-03 0,04112674 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 7,528E-03 0,04102928 ! T cell mediated immunity GO:0002456 12 6 0,000 7,528E-03 0,04093229 ! male sex determination GO:0030238 9 6 0,000 7,528E-03 0,04083575 ! carnitine transport GO:0015879 8 6 0,000 7,528E-03 0,04073966 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 7,528E-03 0,04064403 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 7,528E-03 0,04054885 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 7,528E-03 0,04045411 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 7,528E-03 0,04035981 ! positive regulation of exocytosis GO:0045921 6 6 0,000 7,528E-03 0,04026595 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 7,528E-03 0,04017252 ! parturition GO:0007567 12 6 0,000 7,528E-03 0,04007953 ! negative regulation of translational initiation GO:0045947 7 6 0,000 7,528E-03 0,03998697 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 7,528E-03 0,03989483 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 7,528E-03 0,03980312 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 7,528E-03 0,03971183 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 7,528E-03 0,03962096 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 7,528E-03 0,0395305 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 7,528E-03 0,03944045 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 7,528E-03 0,03935081 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 7,528E-03 0,03926158 ! macrophage differentiation GO:0030225 10 6 0,000 7,528E-03 0,03917275 ! astrocyte development GO:0014002 14 6 0,000 7,528E-03 0,03908433 ! hyaluronan metabolic process GO:0030212 6 6 0,000 7,528E-03 0,0389963 ! purine base biosynthetic process GO:0009113 14 6 0,000 7,528E-03 0,03890867 ! interaction with symbiont GO:0051702 8 6 0,000 7,528E-03 0,03882143 ! anterograde axon cargo transport GO:0008089 8 6 0,000 7,528E-03 0,03873458 ! skeletal muscle contraction GO:0003009 6 6 0,000 7,528E-03 0,03864812 ! eating behavior GO:0042755 6 6 0,000 7,528E-03 0,03856204 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 7,528E-03 0,03847635 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 7,528E-03 0,03839104 ! response to copper ion GO:0046688 9 6 0,000 7,528E-03 0,0383061 ! DNA topological change GO:0006265 8 6 0,000 7,528E-03 0,03822154 ! response to exogenous dsRNA GO:0043330 8 6 0,000 7,528E-03 0,03813735 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 7,528E-03 0,03805353 ! establishment of melanosome localization GO:0032401 9 6 0,000 7,528E-03 0,03797008 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 7,528E-03 0,037887 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 7,528E-03 0,03780427 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 7,528E-03 0,03772191 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 7,528E-03 0,03763991 ! nucleoside catabolic process GO:0009164 6 6 0,000 7,528E-03 0,03755826 ! gas homeostasis GO:0033483 11 6 0,000 7,528E-03 0,03747696 ! hair follicle maturation GO:0048820 7 6 0,000 7,528E-03 0,03739602 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 7,528E-03 0,03731543 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 7,528E-03 0,03723518 ! Schwann cell development GO:0014044 14 6 0,000 7,528E-03 0,03715527 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 7,528E-03 0,03707571 ! dendrite morphogenesis GO:0048813 9 6 0,000 7,528E-03 0,03699649 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 7,528E-03 0,03691761 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 7,528E-03 0,03683906 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 7,528E-03 0,03676084 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 7,528E-03 0,03668296 ! histone ubiquitination GO:0016574 7 6 0,000 7,528E-03 0,03660541 ! regulation of meiosis GO:0040020 10 6 0,000 7,528E-03 0,03652818 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 7,528E-03 0,03645128 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 7,528E-03 0,0363747 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 7,528E-03 0,03629844 ! regulation of mast cell activation GO:0033003 6 6 0,000 7,528E-03 0,03622251 ! membrane to membrane docking GO:0022614 12 6 0,000 7,528E-03 0,03614688 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 7,528E-03 0,03607158 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 7,528E-03 0,03599659 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 7,528E-03 0,0359219 ! receptor internalization GO:0031623 9 6 0,000 7,528E-03 0,03584753 ! neutrophil homeostasis GO:0001780 6 6 0,000 7,528E-03 0,03577347 ! coenzyme A metabolic process GO:0015936 9 6 0,000 7,528E-03 0,03569971 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 7,528E-03 0,03562625 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 7,528E-03 0,0355531 ! protein deubiquitination GO:0016579 8 6 0,000 7,528E-03 0,03548024 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 7,528E-03 0,03540768 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 7,528E-03 0,03533542 ! peptidyl-histidine modification GO:0018202 9 6 0,000 7,528E-03 0,03526346 ! axonal fasciculation GO:0007413 9 6 0,000 7,528E-03 0,03519178 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 7,528E-03 0,0351204 ! thiamin metabolic process GO:0006772 6 6 0,000 7,528E-03 0,03504931 ! midbrain development GO:0030901 6 6 0,000 7,528E-03 0,0349785 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 7,528E-03 0,03490798 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 7,528E-03 0,03483774 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 7,528E-03 0,03476779 ! progesterone metabolic process GO:0042448 8 6 0,000 7,528E-03 0,03469811 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 7,528E-03 0,03462872 ! glycolipid catabolic process GO:0019377 13 6 0,000 7,528E-03 0,0345596 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 7,528E-03 0,03449075 ! positive regulation of glucose import GO:0046326 6 6 0,000 7,528E-03 0,03442218 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 7,528E-03 0,03435388 ! adult feeding behavior GO:0008343 6 6 0,000 7,528E-03 0,03428586 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 7,528E-03 0,0342181 ! blastocyst growth GO:0001832 15 6 0,000 7,528E-03 0,03415061 ! pigment granule transport GO:0051904 12 6 0,000 7,528E-03 0,03408338 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 7,528E-03 0,03401642 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 7,528E-03 0,03394972 ! catecholamine transport GO:0051937 7 6 0,000 7,528E-03 0,03388328 ! organ or tissue specific immune response GO:0002251 7 6 0,000 7,528E-03 0,0338171 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 7,528E-03 0,03375118 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 7,528E-03 0,03368552 ! negative regulation of B cell activation GO:0050869 9 6 0,000 7,528E-03 0,03362011 ! protein prenylation GO:0018342 10 6 0,000 7,528E-03 0,03355496 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 7,528E-03 0,03349005 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 7,528E-03 0,0334254 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 7,528E-03 0,033361 ! positive regulation of coagulation GO:0050820 11 6 0,000 7,528E-03 0,03329684 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 8,777E-03 0,03874848 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 8,777E-03 0,03867425 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 8,777E-03 0,03860031 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 8,777E-03 0,03852664 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 8,777E-03 0,03845326 ! synaptonemal complex assembly GO:0007130 10 7 0,000 8,777E-03 0,03838015 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 8,777E-03 0,03830733 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 8,777E-03 0,03823477 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 8,777E-03 0,0381625 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 8,777E-03 0,03809049 ! reproductive behavior GO:0019098 12 7 0,000 8,777E-03 0,03801876 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 8,777E-03 0,03794729 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 8,777E-03 0,0378761 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 8,777E-03 0,03780517 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 8,777E-03 0,03773451 ! oligopeptide transport GO:0006857 11 7 0,000 8,777E-03 0,03766411 ! protein amino acid sulfation GO:0006477 9 7 0,000 8,777E-03 0,03759397 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 8,777E-03 0,03752409 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 8,777E-03 0,03745447 ! RNA methylation GO:0001510 11 7 0,000 8,777E-03 0,03738511 ! pericardium development GO:0060039 8 7 0,000 8,777E-03 0,03731601 ! macrophage chemotaxis GO:0048246 10 7 0,000 8,777E-03 0,03724716 ! fibril organization GO:0043206 13 7 0,000 8,777E-03 0,03717856 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 8,777E-03 0,03711022 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 8,777E-03 0,03704213 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 8,777E-03 0,03697429 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 8,777E-03 0,03690669 ! lipoprotein transport GO:0042953 9 7 0,000 8,777E-03 0,03683934 ! cerebral cortex cell migration GO:0021795 11 7 0,000 8,777E-03 0,03677224 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 8,777E-03 0,03670538 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 8,777E-03 0,03663877 ! estrogen metabolic process GO:0008210 14 7 0,000 8,777E-03 0,03657239 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 8,777E-03 0,03650626 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 8,777E-03 0,03644036 ! chemosensory behavior GO:0007635 9 7 0,000 8,777E-03 0,0363747 ! microtubule bundle formation GO:0001578 8 7 0,000 8,777E-03 0,03630928 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 8,777E-03 0,03624409 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 8,777E-03 0,03617914 ! leukocyte degranulation GO:0043299 10 7 0,000 8,777E-03 0,03611442 ! bile acid and bile salt transport GO:0015721 9 7 0,000 8,777E-03 0,03604993 ! reflex GO:0060004 12 7 0,000 8,777E-03 0,03598567 ! positive regulation of isotype switching GO:0045830 15 7 0,000 8,777E-03 0,03592164 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 8,777E-03 0,03585783 ! protein-cofactor linkage GO:0018065 13 7 0,000 8,777E-03 0,03579426 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 8,777E-03 0,0357309 ! glycerolipid catabolic process GO:0046503 9 7 0,000 8,777E-03 0,03566777 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 8,777E-03 0,03560487 ! spinal cord patterning GO:0021511 7 7 0,000 8,777E-03 0,03554218 ! hemoglobin metabolic process GO:0020027 10 7 0,000 8,777E-03 0,03547972 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 8,777E-03 0,03541747 ! adrenal gland development GO:0030325 17 7 0,000 8,777E-03 0,03535545 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 8,777E-03 0,03529364 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 8,777E-03 0,03523204 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 8,777E-03 0,03517066 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 8,777E-03 0,0351095 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 8,777E-03 0,03504854 ! endosome organization GO:0007032 10 7 0,000 8,777E-03 0,0349878 ! thyroid hormone generation GO:0006590 11 7 0,000 8,777E-03 0,03492727 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 8,777E-03 0,03486694 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 8,777E-03 0,03480683 ! regulation of pigmentation during development GO:0048070 15 7 0,000 8,777E-03 0,03474692 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 8,777E-03 0,03468722 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 8,777E-03 0,03462772 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 8,777E-03 0,03456843 ! galactose metabolic process GO:0006012 10 7 0,000 8,777E-03 0,03450933 ! vesicle fusion GO:0006906 15 7 0,000 8,777E-03 0,03445044 ! intracellular pH reduction GO:0051452 10 7 0,000 8,777E-03 0,03439176 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 8,777E-03 0,03433327 ! organ growth GO:0035265 11 7 0,000 8,777E-03 0,03427498 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 8,777E-03 0,03421688 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 8,777E-03 0,03415899 ! Rac protein signal transduction GO:0016601 7 7 0,000 8,777E-03 0,03410128 ! retinol metabolic process GO:0042572 9 7 0,000 8,777E-03 0,03404378 ! behavioral fear response GO:0001662 13 7 0,000 8,777E-03 0,03398647 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 8,777E-03 0,03392935 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 8,777E-03 0,03387242 ! rRNA modification GO:0000154 12 7 0,000 8,777E-03 0,03381568 ! protein heterooligomerization GO:0051291 10 7 0,000 8,777E-03 0,03375913 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 8,777E-03 0,03370277 ! response to UV-B GO:0010224 11 7 0,000 8,777E-03 0,0336466 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 8,777E-03 0,03359062 ! protein retention in ER lumen GO:0006621 12 7 0,000 8,777E-03 0,03353482 ! intermediate filament organization GO:0045109 11 7 0,000 8,777E-03 0,0334792 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 8,777E-03 0,03342378 ! cardiac muscle cell development GO:0055013 9 7 0,000 8,777E-03 0,03336853 ! fibrinolysis GO:0042730 9 7 0,000 8,777E-03 0,03331347 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 8,777E-03 0,03325858 ! regulation of circadian rhythm GO:0042752 11 7 0,000 8,777E-03 0,03320388 ! B cell lineage commitment GO:0002326 17 7 0,000 8,777E-03 0,03314936 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 8,777E-03 0,03309502 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 8,777E-03 0,03304085 ! response to tropane GO:0014073 13 7 0,000 8,777E-03 0,03298686 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 8,777E-03 0,03293305 ! melanosome localization GO:0032400 10 7 0,000 8,777E-03 0,03287941 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 8,777E-03 0,03282595 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 8,777E-03 0,03277266 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 8,777E-03 0,03271955 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 8,777E-03 0,0326666 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 8,777E-03 0,03261383 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 8,777E-03 0,03256123 ! mast cell activation GO:0045576 9 7 0,000 8,777E-03 0,03250879 ! multicellular organismal aging GO:0010259 11 7 0,000 8,777E-03 0,03245653 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 8,777E-03 0,03240443 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 8,777E-03 0,0323525 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 8,777E-03 0,03230074 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 8,777E-03 0,03224914 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 8,777E-03 0,0321977 ! establishment of nucleus localization GO:0040023 13 7 0,000 8,777E-03 0,03214643 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 8,777E-03 0,03209533 ! T cell lineage commitment GO:0002360 12 7 0,000 8,777E-03 0,03204438 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 8,777E-03 0,0319936 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 8,777E-03 0,03194298 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 8,777E-03 0,03189251 ! regulation of lipid transport GO:0032368 13 7 0,000 8,777E-03 0,03184221 ! response to tumor cell GO:0002347 12 7 0,000 8,777E-03 0,03179206 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 8,777E-03 0,03174208 ! neuroblast proliferation GO:0007405 13 7 0,000 8,777E-03 0,03169225 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 8,777E-03 0,03164257 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 8,777E-03 0,03159305 ! peptidyl-threonine modification GO:0018210 18 7 0,000 8,777E-03 0,03154369 ! diuresis GO:0030146 12 7 0,000 8,777E-03 0,03149448 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 8,777E-03 0,03144542 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 8,777E-03 0,03139652 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 8,777E-03 0,03134776 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 8,777E-03 0,03129916 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 8,777E-03 0,03125071 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 8,777E-03 0,03120241 ! melanin biosynthetic process GO:0042438 8 7 0,000 8,777E-03 0,03115426 ! regulation of synaptogenesis GO:0051963 10 7 0,000 8,777E-03 0,03110626 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 8,777E-03 0,0310584 ! dopamine biosynthetic process GO:0042416 15 7 0,000 8,777E-03 0,03101069 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 8,777E-03 0,03096313 ! lymph node development GO:0048535 9 7 0,000 8,777E-03 0,03091571 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 8,777E-03 0,03086844 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 8,777E-03 0,03082131 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 8,777E-03 0,03077433 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 8,777E-03 0,03072749 ! endosome to lysosome transport GO:0008333 10 7 0,000 8,777E-03 0,03068079 ! ATP catabolic process GO:0006200 10 7 0,000 8,777E-03 0,03063423 ! establishment of pigment granule localization GO:0051905 13 7 0,000 8,777E-03 0,03058782 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 8,777E-03 0,03054154 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 8,777E-03 0,03049541 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 8,777E-03 0,03044941 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 8,777E-03 0,03040355 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 8,777E-03 0,03035784 ! muscle adaptation GO:0043500 12 7 0,000 8,777E-03 0,03031225 ! amino sugar catabolic process GO:0046348 9 7 0,000 8,777E-03 0,03026681 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 8,777E-03 0,0302215 ! retina homeostasis GO:0001895 9 7 0,000 8,777E-03 0,03017632 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 8,777E-03 0,03013128 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 8,777E-03 0,03008638 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 8,777E-03 0,03004161 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 8,777E-03 0,02999697 ! behavioral response to nicotine GO:0035095 11 7 0,000 8,777E-03 0,02995246 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 8,777E-03 0,02990809 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 8,777E-03 0,02986385 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,01002527 0,03405925 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,01002527 0,03400901 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 0,01002527 0,03395893 ! axon extension GO:0048675 11 8 0,000 0,01002527 0,03390899 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,01002527 0,03385919 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,01002527 0,03380955 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,01002527 0,03376004 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,01002527 0,03371069 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,01002527 0,03366147 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,01002527 0,03361241 ! positive regulation of B cell proliferation GO:0030890 11 8 0,000 0,01002527 0,03356348 ! phosphate transport GO:0006817 10 8 0,000 0,01002527 0,03351469 ! N-glycan processing GO:0006491 12 8 0,000 0,01002527 0,03346605 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,01002527 0,03341755 ! UTP metabolic process GO:0046051 8 8 0,000 0,01002527 0,03336919 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,01002527 0,03332097 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,01002527 0,03327289 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 10 8 0,000 0,01002527 0,03322494 ! succinate metabolic process GO:0006105 14 8 0,000 0,01002527 0,03317714 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,01002527 0,03312947 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,01002527 0,03308194 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01002527 0,03303454 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,01002527 0,03298728 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,01002527 0,03294016 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,01002527 0,03289317 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,01002527 0,03284631 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,01002527 0,03279959 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01002527 0,032753 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,01002527 0,03270654 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,01002527 0,03266021 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,01002527 0,03261402 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,01002527 0,03256795 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,01002527 0,03252202 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,01002527 0,03247621 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,01002527 0,03243053 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,01002527 0,03238499 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 0,000 0,01002527 0,03233957 ! astrocyte differentiation GO:0048708 16 8 0,000 0,01002527 0,03229427 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,01002527 0,03224911 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,01002527 0,03220406 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,01002527 0,03215915 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,01002527 0,03211436 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,01002527 0,03206969 ! melanin metabolic process GO:0006582 12 8 0,000 0,01002527 0,03202515 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,01002527 0,03198074 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01002527 0,03193644 ! macrophage activation GO:0042116 12 8 0,000 0,01002527 0,03189227 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,01002527 0,03184822 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,01002527 0,03180429 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,01002527 0,03176048 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,01002527 0,0317168 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,01002527 0,03167323 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,01002527 0,03162978 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,01002527 0,03158645 ! ruffle organization GO:0031529 11 8 0,000 0,01002527 0,03154324 ! osteoblast development GO:0002076 13 8 0,000 0,01002527 0,03150015 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,01002527 0,03145718 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,01002527 0,03141432 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,01002527 0,03137158 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,01002527 0,03132895 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,01002527 0,03128645 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,01002527 0,03124405 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,01002527 0,03120177 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,01002527 0,03115961 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,01002527 0,03111756 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,01002527 0,03107562 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,01002527 0,0310338 ! oligodendrocyte development GO:0014003 8 8 0,000 0,01002527 0,03099208 ! segment specification GO:0007379 10 8 0,000 0,01002527 0,03095048 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,01002527 0,03090899 ! cellular extravasation GO:0045123 11 8 0,000 0,01002527 0,03086762 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,01002527 0,03082635 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,01002527 0,03078519 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,01002527 0,03074415 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,01002527 0,03070321 ! snRNA metabolic process GO:0016073 10 8 0,000 0,01002527 0,03066238 GO:0016180|snRNA processing, ! phosphoinositide 3-kinase cascade GO:0014065 23 8 0,000 0,01002527 0,03062166 ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,01002527 0,03058105 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,01002527 0,03054054 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,01002527 0,03050015 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,01002527 0,03045985 ! nucleosome disassembly GO:0006337 12 8 0,000 0,01002527 0,03041967 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,01002527 0,03037959 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,01002527 0,03033962 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,01002527 0,03029975 ! icosanoid secretion GO:0032309 12 8 0,000 0,01002527 0,03025999 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,01002527 0,03022033 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01002527 0,03018077 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,01002527 0,03014132 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,01002527 0,03010197 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,01002527 0,03006273 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,01002527 0,03002358 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,01002527 0,02998454 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,01002527 0,0299456 ! sterol catabolic process GO:0016127 9 8 0,000 0,01002527 0,02990676 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,01002527 0,02986802 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,01002527 0,02982938 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,01002527 0,02979084 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,01002527 0,0297524 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01002527 0,02971406 ! prophase GO:0051324 11 8 0,000 0,01002527 0,02967582 ! S phase GO:0051320 8 8 0,000 0,01002527 0,02963767 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,01002527 0,02959963 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,01002527 0,02956168 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,01002527 0,02952383 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,01002527 0,02948607 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,01002527 0,02944842 ! hormone catabolic process GO:0042447 13 8 0,000 0,01002527 0,02941085 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,01002527 0,02937339 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,01002527 0,02933602 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,01002527 0,02929874 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,01002527 0,02926156 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,01002527 0,02922447 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,01002527 0,02918748 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,01002527 0,02915058 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01002527 0,02911378 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,01002527 0,02907706 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,01002527 0,02904044 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,01002527 0,02900391 ! lamellipodium assembly GO:0030032 9 8 0,000 0,01002527 0,02896748 ! regulation of embryonic development GO:0045995 16 8 0,000 0,01002527 0,02893113 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01002527 0,02889487 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,01002527 0,02885871 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,01127166 0,03240601 ! regulation of developmental growth GO:0048638 13 9 0,000 0,01127166 0,03236556 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,01127166 0,0323252 ! telencephalon cell migration GO:0022029 16 9 0,000 0,01127166 0,03228494 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,01127166 0,03224479 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,01127166 0,03220473 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,01127166 0,03216478 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,01127166 0,03212492 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,01127166 0,03208516 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,01127166 0,0320455 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,01127166 0,03200594 ! GTP metabolic process GO:0046039 9 9 0,000 0,01127166 0,03196647 ! elastic fiber assembly GO:0048251 13 9 0,000 0,01127166 0,03192711 ! social behavior GO:0035176 14 9 0,000 0,01127166 0,03188784 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,01127166 0,03184866 ! artery development GO:0060840 19 9 0,000 0,01127166 0,03180958 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,01127166 0,0317706 ! regulation of glycolysis GO:0006110 15 9 0,000 0,01127166 0,03173171 ! response to pain GO:0048265 16 9 0,000 0,01127166 0,03169292 ! protein complex disassembly GO:0043241 17 9 0,000 0,01127166 0,03165423 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,01127166 0,03161562 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,01127166 0,03157711 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,01127166 0,0315387 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,01127166 0,03150038 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,01127166 0,03146215 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,01127166 0,03142401 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,01127166 0,03138597 ! ventral spinal cord development GO:0021517 11 9 0,000 0,01127166 0,03134802 ! protein targeting to ER GO:0045047 19 9 0,000 0,01127166 0,03131016 ! T cell selection GO:0045058 18 9 0,000 0,01127166 0,03127239 ! endoderm development GO:0007492 12 9 0,000 0,01127166 0,03123471 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,01127166 0,03119712 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,01127166 0,03115963 ! arginine catabolic process GO:0006527 10 9 0,000 0,01127166 0,03112222 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,01127166 0,0310849 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,01127166 0,03104768 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,01127166 0,03101054 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01127166 0,03097349 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,01127166 0,03093653 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,01127166 0,03089965 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,01127166 0,03086287 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,01127166 0,03082617 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01127166 0,03078956 ! mannose metabolic process GO:0006013 9 9 0,000 0,01127166 0,03075304 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,01127166 0,0307166 ! receptor clustering GO:0043113 15 9 0,000 0,01127166 0,03068025 ! epithelial cell development GO:0002064 10 9 0,000 0,01127166 0,03064398 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,01127166 0,0306078 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,01127166 0,03057171 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,01127166 0,0305357 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,01127166 0,03049978 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,01127166 0,03046394 ! motor axon guidance GO:0008045 14 9 0,000 0,01127166 0,03042818 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,01127166 0,03039251 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,01127166 0,03035692 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,01127166 0,03032142 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,01127166 0,03028599 ! blastoderm segmentation GO:0007350 11 9 0,000 0,01127166 0,03025065 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,01127166 0,0302154 ! DNA ligation GO:0006266 14 9 0,000 0,01127166 0,03018022 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,01127166 0,03014513 ! response to amine stimulus GO:0014075 13 9 0,000 0,01127166 0,03011012 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,01127166 0,03007519 ! erythrocyte development GO:0048821 11 9 0,000 0,01127166 0,03004034 ! renal water homeostasis GO:0003091 14 9 0,000 0,01127166 0,03000557 ! postreplication repair GO:0006301 11 9 0,000 0,01127166 0,02997088 ! mRNA cleavage GO:0006379 13 9 0,000 0,01127166 0,02993627 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,01127166 0,02990174 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,01127166 0,02986729 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,01127166 0,02983292 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,01127166 0,02979863 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,01127166 0,02976442 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,01127166 0,02973029 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,01127166 0,02969623 ! acid secretion GO:0046717 14 9 0,000 0,01127166 0,02966225 ! musculoskeletal movement GO:0050881 11 9 0,000 0,01127166 0,02962835 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,01127166 0,02959453 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,01127166 0,02956079 ! purine base metabolic process GO:0006144 18 9 0,000 0,01127166 0,02952712 ! oocyte differentiation GO:0009994 12 9 0,000 0,01127166 0,02949353 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,01127166 0,02946001 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,01127166 0,02942657 ! spleen development GO:0048536 15 9 0,000 0,01127166 0,02939321 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,01127166 0,02935992 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,01127166 0,02932671 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,01127166 0,02929357 ! detection of calcium ion GO:0005513 13 9 0,000 0,01127166 0,02926051 ! blastocyst formation GO:0001825 12 9 0,000 0,01127166 0,02922752 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,01127166 0,02919461 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,01127166 0,02916177 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,01127166 0,029129 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,01127166 0,02909631 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01127166 0,02906369 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,01127166 0,02903114 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,01127166 0,02899867 ! prepulse inhibition GO:0060134 14 9 0,000 0,01127166 0,02896627 ! embryonic placenta development GO:0001892 12 9 0,000 0,01127166 0,02893394 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,01127166 0,02890168 ! insulin secretion GO:0030073 17 9 0,000 0,01127166 0,0288695 ! sequestering of metal ion GO:0051238 11 9 0,000 0,01127166 0,02883739 ! response to nicotine GO:0035094 16 9 0,000 0,01127166 0,02880534 ! establishment of cell polarity GO:0030010 12 9 0,000 0,01127166 0,02877337 ! nucleus localization GO:0051647 15 9 0,000 0,01127166 0,02874148 ! regulation of synapse organization GO:0050807 12 9 0,000 0,01127166 0,02870965 ! localization within membrane GO:0051668 15 9 0,000 0,01127166 0,02867789 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,01251655 0,03181002 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,01251655 0,03177491 ! neuron fate specification GO:0048665 11 10 0,000 0,01251655 0,03173987 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,01251655 0,03170492 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,01251655 0,03167004 ! thyroid gland development GO:0030878 19 10 0,000 0,01251655 0,03163524 ! regulation of B cell proliferation GO:0030888 15 10 0,000 0,01251655 0,03160051 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,01251655 0,03156586 ! synapsis GO:0007129 13 10 0,000 0,01251655 0,03153129 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,01251655 0,03149679 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,01251655 0,03146237 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,01251655 0,03142802 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,01251655 0,03139375 ! sulfate transport GO:0008272 12 10 0,000 0,01251655 0,03135955 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,01251655 0,03132542 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,01251655 0,03129138 ! androgen metabolic process GO:0008209 13 10 0,000 0,01251655 0,0312574 ! phospholipid efflux GO:0033700 16 10 0,000 0,01251655 0,0312235 ! hippocampus development GO:0021766 19 10 0,000 0,01251655 0,03118967 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,01251655 0,03115591 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,01251655 0,03112223 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,01251655 0,03108862 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,01251655 0,03105509 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,01251655 0,03102162 ! pathogenesis GO:0009405 13 10 0,000 0,01251655 0,03098823 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,01251655 0,03095491 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01251655 0,03092166 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,01251655 0,03088848 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 0,01251655 0,03085538 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,01251655 0,03082234 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,01251655 0,03078937 ! melanocyte differentiation GO:0030318 15 10 0,000 0,01251655 0,03075648 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,01251655 0,03072366 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,01251655 0,0306909 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,01251655 0,03065822 ! response to X-ray GO:0010165 16 10 0,000 0,01251655 0,0306256 ! B cell proliferation GO:0042100 14 10 0,000 0,01251655 0,03059306 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,01251655 0,03056058 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,01251655 0,03052817 ! forebrain cell migration GO:0021885 17 10 0,000 0,01251655 0,03049583 ! lipid digestion GO:0044241 15 10 0,000 0,01251655 0,03046356 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,01251655 0,03043136 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,01251655 0,03039922 ! UV protection GO:0009650 14 10 0,000 0,01251655 0,03036716 ! entry into host cell GO:0030260 20 10 0,000 0,01251655 0,03033516 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,01251655 0,03030323 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,01251655 0,03027136 ! negative regulation of ossification GO:0030279 19 10 0,000 0,01251655 0,03023956 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,01251655 0,03020783 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,01251655 0,03017617 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,01251655 0,03014457 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,01251655 0,03011304 ! regulation of organ growth GO:0046620 11 10 0,000 0,01251655 0,03008157 ! response to dsRNA GO:0043331 18 10 0,000 0,01251655 0,03005017 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,01251655 0,03001884 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,01251655 0,02998757 ! embryonic axis specification GO:0000578 12 10 0,000 0,01251655 0,02995636 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,01251655 0,02992522 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,01251655 0,02989415 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,01251655 0,02986314 ! cranial nerve development GO:0021545 12 10 0,000 0,01251655 0,02983219 ! fucose catabolic process GO:0019317 16 10 0,000 0,01251655 0,02980131 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,01251655 0,02977049 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,01251655 0,02973974 ! protein sumoylation GO:0016925 12 10 0,000 0,01251655 0,02970905 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,01251655 0,02967842 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01251655 0,02964785 ! zymogen activation GO:0031638 14 10 0,000 0,01251655 0,02961735 ! salivary gland development GO:0007431 22 10 0,000 0,01251655 0,02958691 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,01251655 0,02955654 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,01251655 0,02952622 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,01251655 0,02949597 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,01251655 0,02946578 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,01251655 0,02943565 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,01251655 0,02940558 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,01251655 0,02937558 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,01251655 0,02934563 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,01251655 0,02931575 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,01251655 0,02928593 ! detection of bacterium GO:0016045 10 10 0,000 0,01251655 0,02925616 ! embryonic gut development GO:0048566 11 10 0,000 0,01251655 0,02922646 ! activation of innate immune response GO:0002218 10 10 0,000 0,01251655 0,02919682 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,01251655 0,02916724 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,01251655 0,02913772 ! developmental induction GO:0031128 13 10 0,000 0,01251655 0,02910826 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,01251655 0,02907885 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,01251655 0,02904951 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,01251655 0,02902023 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,01251655 0,028991 ! rRNA transcription GO:0009303 17 11 0,000 0,01375995 0,03183891 ! respiratory burst GO:0045730 14 11 0,000 0,01375995 0,03180691 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,01375995 0,03177498 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,01375995 0,03174311 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,01375995 0,0317113 ! virus-host interaction GO:0019048 17 11 0,000 0,01375995 0,03167956 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 0,01375995 0,03164788 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,01375995 0,03161626 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,01375995 0,03158471 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,01375995 0,03155322 ! RNA polyadenylation GO:0043631 19 11 0,000 0,01375995 0,03152179 ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,01375995 0,03149043 ! mating GO:0007618 14 11 0,000 0,01375995 0,03145912 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,01375995 0,03142788 ! T cell proliferation GO:0042098 20 11 0,000 0,01375995 0,03139671 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,01375995 0,03136559 ! bone resorption GO:0045453 16 11 0,000 0,01375995 0,03133453 ! regulated secretory pathway GO:0045055 14 11 0,000 0,01375995 0,03130354 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,01375995 0,03127261 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,01375995 0,03124174 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,01375995 0,03121093 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,01375995 0,03118018 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,01375995 0,03114949 ! syncytium formation GO:0006949 15 11 0,000 0,01375995 0,03111886 ! plasma membrane organization GO:0007009 18 11 0,000 0,01375995 0,03108829 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,01375995 0,03105778 ! focal adhesion formation GO:0048041 24 11 0,000 0,01375995 0,03102733 ! mitotic spindle organization GO:0007052 15 11 0,000 0,01375995 0,03099694 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,01375995 0,03096661 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,01375995 0,03093634 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,01375995 0,03090613 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,01375995 0,03087598 ! adult heart development GO:0007512 11 11 0,000 0,01375995 0,03084589 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,01375995 0,03081585 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,01375995 0,03078587 ! temperature homeostasis GO:0001659 16 11 0,000 0,01375995 0,03075596 ! L-glutamate transport GO:0015813 16 11 0,000 0,01375995 0,0307261 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,01375995 0,03069629 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,01375995 0,03066655 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,01375995 0,03063686 ! stem cell development GO:0048864 29 11 0,000 0,01375995 0,03060723 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,01375995 0,03057766 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,01375995 0,03054815 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,01375995 0,03051869 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,01375995 0,03048929 ! vasoconstriction GO:0042310 15 11 0,000 0,01375995 0,03045994 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,01375995 0,03043065 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,01375995 0,03040142 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,01375995 0,03037224 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,01375995 0,03034312 ! ribosome assembly GO:0042255 13 11 0,000 0,01375995 0,03031406 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,01375995 0,03028505 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,01375995 0,0302561 ! chromatin silencing GO:0006342 19 11 0,000 0,01375995 0,0302272 ! nucleosome positioning GO:0016584 13 11 0,000 0,01375995 0,03019836 ! T cell homeostasis GO:0043029 20 11 0,000 0,01375995 0,03016957 ! regulation of isotype switching GO:0045191 19 11 0,000 0,01375995 0,03014084 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,01375995 0,03011216 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,01375995 0,03008354 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,01375995 0,03005497 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,01375995 0,03002645 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,01375995 0,02999799 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,01375995 0,02996958 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,01375995 0,02994123 ! male genitalia development GO:0030539 13 11 0,000 0,01375995 0,02991293 ! cholesterol efflux GO:0033344 19 11 0,000 0,01375995 0,02988468 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,01375995 0,02985649 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,01375995 0,02982835 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,01375995 0,02980026 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,01375995 0,02977223 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,01375995 0,02974425 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,01375995 0,02971632 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,01375995 0,02968844 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,01375995 0,02966062 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,01375995 0,02963285 ! lysogeny GO:0030069 18 11 0,000 0,01375995 0,02960513 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,01375995 0,02957746 ! acrosome reaction GO:0007340 13 11 0,000 0,01375995 0,02954984 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,01375995 0,02952228 ! lactation GO:0007595 20 12 0,000 0,01500185 0,03215681 ! reproductive cellular process GO:0048610 14 12 0,000 0,01500185 0,03212687 ! tRNA modification GO:0006400 14 12 0,000 0,01500185 0,03209698 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,01500185 0,03206715 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,01500185 0,03203738 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,01500185 0,03200766 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,01500185 0,03197799 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,01500185 0,03194838 ! non-recombinational repair GO:0000726 19 12 0,000 0,01500185 0,03191883 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,01500185 0,03188933 ! peroxisomal transport GO:0043574 21 12 0,000 0,01500185 0,03185988 ! cartilage condensation GO:0001502 18 12 0,000 0,01500185 0,03183049 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,01500185 0,03180116 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,01500185 0,03177187 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,01500185 0,03174264 ! heart looping GO:0001947 15 12 0,000 0,01500185 0,03171347 ! palate development GO:0060021 15 12 0,000 0,01500185 0,03168435 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,01500185 0,03165528 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,01500185 0,03162626 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,01500185 0,0315973 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,01500185 0,03156839 ! arginine metabolic process GO:0006525 13 12 0,000 0,01500185 0,03153954 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,01500185 0,03151074 ! methionine metabolic process GO:0006555 13 12 0,000 0,01500185 0,03148198 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,01500185 0,03145329 ! Golgi organization GO:0007030 18 12 0,000 0,01500185 0,03142464 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,01500185 0,03139605 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,01500185 0,0313675 ! monoamine transport GO:0015844 13 12 0,000 0,01500185 0,03133901 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01500185 0,03131058 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,01500185 0,03128219 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,01500185 0,03125385 ! L-amino acid transport GO:0015807 20 12 0,000 0,01500185 0,03122557 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,01500185 0,03119734 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,01500185 0,03116916 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,01500185 0,03114102 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,01500185 0,03111294 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,01500185 0,03108491 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,01500185 0,03105694 ! cerebellum development GO:0021549 13 12 0,000 0,01500185 0,03102901 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,01500185 0,03100113 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,01500185 0,0309733 ! histone acetylation GO:0016573 23 12 0,000 0,01500185 0,03094552 ! histone methylation GO:0016571 15 12 0,000 0,01500185 0,03091779 ! autonomic nervous system development GO:0048483 23 12 0,000 0,01500185 0,03089011 ! gland morphogenesis GO:0022612 23 12 0,000 0,01500185 0,03086248 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,01500185 0,0308349 ! peptidyl-lysine modification GO:0018205 18 12 0,000 0,01500185 0,03080737 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,01500185 0,03077989 ! response to gamma radiation GO:0010332 20 12 0,000 0,01500185 0,03075246 ! regulation of epidermis development GO:0045682 17 12 0,000 0,01500185 0,03072507 ! intestinal absorption GO:0050892 19 12 0,000 0,01500185 0,03069774 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,01500185 0,03067045 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,01500185 0,03064321 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,01500185 0,03061602 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,01500185 0,03058888 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,01500185 0,03056178 ! microspike assembly GO:0030035 23 12 0,000 0,01500185 0,03053474 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,01500185 0,03050774 ! response to cold GO:0009409 14 12 0,000 0,01500185 0,03048079 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 0,01624226 0,03297193 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,01624226 0,03294286 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,01624226 0,03291383 ! cGMP metabolic process GO:0046068 16 13 0,000 0,01624226 0,03288486 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,01624226 0,03285593 ! water transport GO:0006833 17 13 0,000 0,01624226 0,03282706 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,01624226 0,03279824 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,01624226 0,03276947 ! lipid localization GO:0010876 24 13 0,000 0,01624226 0,03274075 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,01624226 0,03271208 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,01624226 0,03268346 ! organelle fusion GO:0048284 28 13 0,000 0,01624226 0,03265489 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,01624226 0,03262637 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,01624226 0,0325979 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,01624226 0,03256948 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,01624226 0,03254111 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,01624226 0,03251279 ! response to hexose stimulus GO:0009746 19 13 0,000 0,01624226 0,03248452 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,01624226 0,0324563 ! glutamate metabolic process GO:0006536 18 13 0,000 0,01624226 0,03242812 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,01624226 0,0324 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,01624226 0,03237192 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,01624226 0,03234389 ! NAD metabolic process GO:0019674 21 13 0,000 0,01624226 0,03231591 ! exocrine system development GO:0035272 27 13 0,000 0,01624226 0,03228798 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,01624226 0,0322601 ! bone mineralization GO:0030282 15 13 0,000 0,01624226 0,03223227 ! regulation of exocytosis GO:0017157 17 13 0,000 0,01624226 0,03220448 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,01624226 0,03217674 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,01624226 0,03214905 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,01624226 0,03212141 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,01624226 0,03209381 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,01624226 0,03206626 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,01624226 0,03203876 ! genitalia development GO:0048806 15 13 0,000 0,01624226 0,03201131 ! regulation of cellular pH GO:0030641 20 13 0,000 0,01624226 0,0319839 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 0,01624226 0,03195654 ! cellular pigmentation GO:0033059 24 13 0,000 0,01624226 0,03192923 ! tissue regeneration GO:0042246 21 13 0,000 0,01624226 0,03190196 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,01624226 0,03187474 ! cofactor transport GO:0051181 19 13 0,000 0,01624226 0,03184757 ! NADP metabolic process GO:0006739 18 13 0,000 0,01624226 0,03182044 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,01624226 0,03179336 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,01624226 0,03176632 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,01624226 0,03173934 ! gas transport GO:0015669 18 13 0,000 0,01624226 0,03171239 ! heme biosynthetic process GO:0006783 20 13 0,000 0,01624226 0,03168549 ! regulation of axon extension GO:0030516 23 13 0,000 0,01624226 0,03165864 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,01624226 0,03163184 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,01624226 0,03160507 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,01624226 0,03157836 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,01624226 0,03155169 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,01624226 0,03152506 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,01624226 0,03149848 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,01748118 0,03387254 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,01748118 0,03384403 ! superoxide anion generation GO:0042554 18 14 0,000 0,01748118 0,03381557 ! neuron maturation GO:0042551 21 14 0,000 0,01748118 0,03378715 ! regulation of S phase GO:0033261 18 14 0,000 0,01748118 0,03375878 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,01748118 0,03373046 ! myotube differentiation GO:0014902 21 14 0,000 0,01748118 0,03370219 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 0,01748118 0,03367396 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,01748118 0,03364578 ! inositol metabolic process GO:0006020 20 14 0,000 0,01748118 0,03361765 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,01748118 0,03358957 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,01748118 0,03356153 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,01748118 0,03353354 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,01748118 0,03350559 ! gene silencing by RNA GO:0031047 20 14 0,000 0,01748118 0,03347769 ! limbic system development GO:0021761 25 14 0,000 0,01748118 0,03344984 ! startle response GO:0001964 21 14 0,000 0,01748118 0,03342204 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,01748118 0,03339428 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,01748118 0,03336656 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,01748118 0,0333389 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,01748118 0,03331128 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,01748118 0,0332837 ! glycine metabolic process GO:0006544 22 14 0,000 0,01748118 0,03325617 ! pituitary gland development GO:0021983 23 14 0,000 0,01748118 0,03322869 ! cellular response to starvation GO:0009267 21 14 0,000 0,01748118 0,03320125 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,01748118 0,03317385 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,01748118 0,03314651 ! regulation of heart rate GO:0002027 23 14 0,000 0,01748118 0,0331192 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,01748118 0,03309194 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,01748118 0,03306473 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,01748118 0,03303756 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,01748118 0,03301044 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,01748118 0,03298336 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,01748118 0,03295632 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,01748118 0,03292933 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,01748118 0,03290238 ! axon cargo transport GO:0008088 27 14 0,000 0,01748118 0,03287548 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,01748118 0,03284862 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,01748118 0,0328218 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,01748118 0,03279503 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,01748118 0,03276831 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,01748118 0,03274162 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,01748118 0,03271498 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,01748118 0,03268838 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,01748118 0,03266183 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,01748118 0,03263532 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,01748118 0,03260885 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,01748118 0,03258242 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,01748118 0,03255604 ! muscle maintenance GO:0046716 19 14 0,000 0,01748118 0,0325297 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,01748118 0,0325034 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,01748118 0,03247715 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,01748118 0,03245094 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,01748118 0,03242477 ! cell killing GO:0001906 20 14 0,000 0,01748118 0,03239864 ! release of cytochrome c from mitochondria GO:0001836 23 14 0,000 0,01748118 0,03237255 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,01748118 0,03234651 ! cilium assembly GO:0042384 20 14 0,000 0,01748118 0,03232051 ! peptide hormone secretion GO:0030072 23 14 0,000 0,01748118 0,03229455 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,01871861 0,03455281 ! positive regulation of cell size GO:0045793 20 15 0,000 0,01871861 0,0345251 ! metencephalon development GO:0022037 19 15 0,000 0,01871861 0,03449743 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,01871861 0,03446981 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,01871861 0,03444224 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,01871861 0,03441471 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,01871861 0,03438722 ! lipid phosphorylation GO:0046834 23 15 0,000 0,01871861 0,03435977 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,01871861 0,03433237 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,01871861 0,03430502 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,01871861 0,03427771 ! bile acid metabolic process GO:0008206 22 15 0,000 0,01871861 0,03425044 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,01871861 0,03422321 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,01871861 0,03419603 ! adult walking behavior GO:0007628 25 15 0,000 0,01871861 0,03416889 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,01871861 0,03414179 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,01871861 0,03411474 ! myoblast differentiation GO:0045445 27 15 0,000 0,01871861 0,03408773 ! centrosome cycle GO:0007098 16 15 0,000 0,01871861 0,03406076 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,01871861 0,03403383 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,01871861 0,03400695 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,01871861 0,03398011 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,01871861 0,03395331 ! cerebral cortex development GO:0021987 29 15 0,000 0,01871861 0,03392655 ! response to osmotic stress GO:0006970 22 15 0,000 0,01871861 0,03389984 ! vesicle coating GO:0006901 25 15 0,000 0,01871861 0,03387317 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,01871861 0,03384654 ! DNA integration GO:0015074 22 15 0,000 0,01871861 0,03381995 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,01871861 0,0337934 ! peptide secretion GO:0002790 27 15 0,000 0,01871861 0,0337669 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,01871861 0,03374044 ! regulation of vasodilation GO:0042312 24 15 0,000 0,01871861 0,03371402 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,01871861 0,03368764 ! neuron recognition GO:0008038 22 15 0,000 0,01871861 0,0336613 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,01871861 0,033635 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,01871861 0,03360874 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,01871861 0,03358253 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,01871861 0,03355635 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,01871861 0,03353022 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,01871861 0,03350412 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,01871861 0,03347807 ! dopamine metabolic process GO:0042417 30 15 0,000 0,01871861 0,03345206 ! organic cation transport GO:0015695 19 15 0,000 0,01871861 0,03342609 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,01871861 0,03340015 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,01871861 0,03337426 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,01871861 0,03334841 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,01871861 0,0333226 ! defense response to virus GO:0051607 27 15 0,000 0,01871861 0,03329683 ! peptide hormone processing GO:0016486 19 15 0,000 0,01871861 0,0332711 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,01871861 0,0332454 ! protein secretion GO:0009306 27 16 0,000 0,01995455 0,03541317 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,01995455 0,03538586 ! hormone secretion GO:0046879 25 16 0,000 0,01995455 0,0353586 ! bone remodeling GO:0046849 24 16 0,000 0,01995455 0,03533138 ! endothelial cell migration GO:0043542 22 16 0,000 0,01995455 0,0353042 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,01995455 0,03527707 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,01995455 0,03524997 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,01995455 0,03522292 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,01995455 0,03519591 ! glial cell development GO:0021782 24 16 0,000 0,01995455 0,03516894 ! patterning of blood vessels GO:0001569 24 16 0,000 0,01995455 0,03514201 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,01995455 0,03511512 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,01995455 0,03508827 ! protein polyubiquitination GO:0000209 26 16 0,000 0,01995455 0,03506147 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,01995455 0,0350347 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,01995455 0,03500798 ! fructose metabolic process GO:0006000 20 16 0,000 0,01995455 0,0349813 ! regulation of protein binding GO:0043393 27 16 0,000 0,01995455 0,03495466 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,01995455 0,03492805 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,01995455 0,03490149 ! protein export from nucleus GO:0006611 24 16 0,000 0,01995455 0,03487497 ! negative regulation of immune response GO:0050777 28 16 0,000 0,01995455 0,03484849 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,01995455 0,03482205 ! DNA replication initiation GO:0006270 25 16 0,000 0,01995455 0,03479565 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,01995455 0,03476929 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,01995455 0,03474297 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,01995455 0,03471669 ! diencephalon development GO:0021536 25 16 0,000 0,01995455 0,03469045 ! oogenesis GO:0048477 23 16 0,000 0,01995455 0,03466425 ! neural crest cell migration GO:0001755 24 16 0,000 0,01995455 0,03463809 ! G1 phase GO:0051318 27 16 0,000 0,01995455 0,03461196 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,01995455 0,03458588 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,01995455 0,03455984 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,01995455 0,03453383 ! steroid catabolic process GO:0006706 22 16 0,000 0,01995455 0,03450787 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,01995455 0,03448194 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,01995455 0,03445605 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,01995455 0,03443021 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,01995455 0,0344044 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,01995455 0,03437862 ! sperm-egg recognition GO:0035036 16 16 0,000 0,01995455 0,03435289 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,01995455 0,0343272 ! nerve development GO:0021675 18 16 0,000 0,01995455 0,03430154 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,01995455 0,03427592 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,01995455 0,03425035 ! negative regulation of translation GO:0017148 22 16 0,000 0,01995455 0,0342248 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,021189 0,03631499 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,021189 0,03628795 ! negative regulation of defense response GO:0031348 19 17 0,000 0,021189 0,03626095 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,021189 0,03623399 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,021189 0,03620707 ! glycerol metabolic process GO:0006071 20 17 0,000 0,021189 0,03618019 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,021189 0,03615335 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,021189 0,03612655 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,021189 0,03609979 ! signal complex assembly GO:0007172 29 17 0,000 0,021189 0,03607307 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,021189 0,03604638 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,021189 0,03601974 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,021189 0,03599314 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,021189 0,03596658 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,021189 0,03594005 ! memory GO:0007613 25 17 0,000 0,021189 0,03591357 ! keratinization GO:0031424 17 17 0,000 0,021189 0,03588712 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,021189 0,03586071 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,021189 0,03583435 ! retinoid metabolic process GO:0001523 22 17 0,000 0,021189 0,03580802 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,021189 0,03578173 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,021189 0,03575547 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,021189 0,03572926 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,021189 0,03570309 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,021189 0,03567695 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,021189 0,03565085 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 0,000 0,021189 0,03562479 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,021189 0,03559877 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,021189 0,03557278 ! membrane budding GO:0006900 29 17 0,000 0,021189 0,03554684 ! heme metabolic process GO:0042168 27 17 0,000 0,021189 0,03552093 ! actin filament bundle formation GO:0051017 26 17 0,000 0,021189 0,03549506 ! neuromuscular junction development GO:0007528 23 17 0,000 0,021189 0,03546922 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,021189 0,03544343 ! body fluid secretion GO:0007589 27 17 0,000 0,021189 0,03541767 ! stem cell differentiation GO:0048863 36 17 0,000 0,021189 0,03539195 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,021189 0,03536626 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,021189 0,03534062 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,021189 0,03531501 ! sensory perception of pain GO:0019233 23 17 0,000 0,021189 0,03528944 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,021189 0,0352639 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,021189 0,0352384 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,021189 0,03521294 ! synaptogenesis GO:0007416 24 17 0,000 0,021189 0,03518752 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,021189 0,03516213 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,021189 0,03513678 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,021189 0,03511146 ! cell-cell junction organization GO:0045216 25 17 0,000 0,021189 0,03508619 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,021189 0,03506094 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,021189 0,03503574 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,021189 0,03501057 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,021189 0,03498544 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,021189 0,03496034 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,02242198 0,03696813 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,02242198 0,03694165 ! positive regulation of translation GO:0045727 28 18 0,000 0,02242198 0,03691521 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,02242198 0,0368888 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,02242198 0,03686243 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,02242198 0,0368361 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,02242198 0,03680981 ! cAMP metabolic process GO:0046058 33 18 0,000 0,02242198 0,03678356 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,02242198 0,03675734 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,02242198 0,03673116 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,02242198 0,03670501 ! axis specification GO:0009798 26 18 0,000 0,02242198 0,03667891 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,02242198 0,03665284 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,02242198 0,03662681 ! pancreas development GO:0031016 26 18 0,000 0,02242198 0,03660081 ! apoptotic mitochondrial changes GO:0008637 29 18 0,000 0,02242198 0,03657485 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,02242198 0,03654893 ! glutamine metabolic process GO:0006541 23 18 0,000 0,02242198 0,03652305 ! response to retinoic acid GO:0032526 25 18 0,000 0,02242198 0,0364972 ! pigmentation during development GO:0048066 31 18 0,000 0,02242198 0,03647139 ! central nervous system neuron development GO:0021954 30 18 0,000 0,02242198 0,03644561 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,02242198 0,03641988 ! fucose metabolic process GO:0006004 26 18 0,000 0,02242198 0,03639417 ! response to fungus GO:0009620 19 18 0,000 0,02242198 0,03636851 ! peptide cross-linking GO:0018149 31 18 0,000 0,02242198 0,03634288 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,02242198 0,03631729 ! heart process GO:0003015 27 18 0,000 0,02242198 0,03629173 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,02242198 0,03626621 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,02242198 0,03624072 ! visual learning GO:0008542 35 18 0,000 0,02242198 0,03621527 ! somitogenesis GO:0001756 24 18 0,000 0,02242198 0,03618986 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,02242198 0,03616448 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,02242198 0,03613913 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,02242198 0,03611383 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,02242198 0,03608855 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,02242198 0,03606332 ! vitamin transport GO:0051180 24 18 0,000 0,02242198 0,03603812 ! hormone transport GO:0009914 27 18 0,000 0,02242198 0,03601295 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,02242198 0,03598782 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,02242198 0,03596272 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,02242198 0,03593766 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,02242198 0,03591264 ! cell-cell recognition GO:0009988 20 18 0,000 0,02242198 0,03588764 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,02242198 0,03586269 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,02242198 0,03583777 ! regulation of glucose import GO:0046324 21 18 0,000 0,02242198 0,03581288 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,02242198 0,03578803 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,02242198 0,03576321 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,02242198 0,03573842 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,02365346 0,03767519 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,02365346 0,03764911 ! positive regulation of fibroblast proliferation GO:0048146 27 19 0,000 0,02365346 0,03762308 ! positive regulation of ossification GO:0045778 30 19 0,000 0,02365346 0,03759708 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,02365346 0,03757111 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,02365346 0,03754518 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,02365346 0,03751929 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,02365346 0,03749343 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,02365346 0,03746761 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,02365346 0,03744182 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,02365346 0,03741607 ! regeneration GO:0031099 32 19 0,000 0,02365346 0,03739036 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,02365346 0,03736468 ! response to alkaloid GO:0043279 32 19 0,000 0,02365346 0,03733903 ! sensory perception of taste GO:0050909 23 19 0,000 0,02365346 0,03731342 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,02365346 0,03728785 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 0,000 0,02365346 0,03726231 ! smooth muscle contraction GO:0006939 36 19 0,000 0,02365346 0,0372368 ! peroxisome organization GO:0007031 29 19 0,000 0,02365346 0,03721133 ! digestive system process GO:0022600 30 19 0,000 0,02365346 0,0371859 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,02365346 0,0371605 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,02365346 0,03713513 ! response to vitamin A GO:0033189 26 19 0,000 0,02365346 0,0371098 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,02365346 0,0370845 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,02365346 0,03705924 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,02365346 0,03703402 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,02365346 0,03700882 ! response to starvation GO:0042594 30 19 0,000 0,02365346 0,03698366 ! sex determination GO:0007530 29 19 0,000 0,02365346 0,03695854 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,02365346 0,03693345 ! plasma membrane fusion GO:0045026 23 19 0,000 0,02365346 0,03690839 ! cytolysis GO:0019835 20 19 0,000 0,02365346 0,03688337 ! renal system process GO:0003014 35 19 0,000 0,02365346 0,03685838 ! vasodilation GO:0042311 33 19 0,000 0,02365346 0,03683342 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,02365346 0,0368085 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,02365346 0,03678362 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,02365346 0,03675876 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,02365346 0,03673394 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,02365346 0,03670916 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,02365346 0,0366844 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,02365346 0,03665968 ! sarcomere organization GO:0045214 23 19 0,000 0,02365346 0,036635 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,02365346 0,03661034 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,02365346 0,03658572 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,02365346 0,03656113 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,02365346 0,03653658 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,02365346 0,03651206 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,02365346 0,03648757 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,02365346 0,03646312 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,02365346 0,03643869 ! protein stabilization GO:0050821 26 19 0,000 0,02365346 0,0364143 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,02488347 0,03828226 ! iron ion transport GO:0006826 37 20 0,000 0,02488347 0,03825668 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,02488347 0,03823112 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,02488347 0,0382056 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,02488347 0,03818011 ! response to vitamin GO:0033273 29 20 0,000 0,02488347 0,03815466 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,02488347 0,03812924 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,02488347 0,03810385 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,02488347 0,0380785 ! spinal cord development GO:0021510 31 20 0,000 0,02488347 0,03805318 ! response to ethanol GO:0045471 37 20 0,000 0,02488347 0,0380279 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,02488347 0,03800265 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 0,000 0,02488347 0,03797743 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,02488347 0,03795225 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,02488347 0,03792709 ! chromosome condensation GO:0030261 31 20 0,000 0,02488347 0,03790198 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,02488347 0,03787689 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,02488347 0,03785184 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,02488347 0,03782682 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,02488347 0,03780184 ! pallium development GO:0021543 38 20 0,000 0,02488347 0,03777689 ! DNA modification GO:0006304 28 20 0,000 0,02488347 0,03775197 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,02488347 0,03772708 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,02488347 0,03770223 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,02488347 0,03767741 ! positive regulation of B cell activation GO:0050871 31 20 0,000 0,02488347 0,03765262 ! collagen catabolic process GO:0030574 25 20 0,000 0,02488347 0,03762787 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,02488347 0,03760314 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,02488347 0,03757845 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,02488347 0,0375538 ! alditol metabolic process GO:0019400 24 20 0,000 0,02488347 0,03752917 ! actin filament-based movement GO:0030048 34 20 0,000 0,02488347 0,03750458 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,026112 0,03933045 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,026112 0,03930471 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,026112 0,03927901 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,026112 0,03925333 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 0,000 0,026112 0,0392277 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,026112 0,03920209 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,026112 0,03917652 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,026112 0,03915098 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,026112 0,03912547 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,026112 0,0391 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,026112 0,03907456 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,026112 0,03904916 ! protein amino acid acylation GO:0043543 37 21 0,000 0,026112 0,03902378 ! vesicle docking GO:0048278 27 21 0,000 0,026112 0,03899844 ! phototransduction GO:0007602 25 21 0,000 0,026112 0,03897314 ! dendrite development GO:0016358 35 21 0,000 0,026112 0,03894786 ! visual behavior GO:0007632 39 21 0,000 0,026112 0,03892262 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,026112 0,03889741 ! ovarian follicle development GO:0001541 30 21 0,000 0,026112 0,03887223 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,026112 0,03884709 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,026112 0,03882198 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,026112 0,0387969 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,026112 0,03877185 ! cell aging GO:0007569 32 21 0,000 0,026112 0,03874684 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,026112 0,03872186 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,026112 0,03869691 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,026112 0,03867199 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,026112 0,03864711 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,026112 0,03862225 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,026112 0,03859743 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,026112 0,03857264 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,026112 0,03854788 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,026112 0,03852316 ! fatty acid transport GO:0015908 30 21 0,000 0,026112 0,03849846 ! immunoglobulin production GO:0002377 33 21 0,000 0,026112 0,0384738 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,026112 0,03844917 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,026112 0,03842457 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,026112 0,0384 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,026112 0,03837546 ! cellular response to extracellular stimulus GO:0031668 32 21 0,000 0,026112 0,03835096 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,026112 0,03832648 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,026112 0,03830204 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,026112 0,03827763 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,026112 0,03825325 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,026112 0,0382289 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,026112 0,03820458 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,026112 0,03818029 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,026112 0,03815604 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,026112 0,03813181 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,026112 0,03810762 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,02733905 0,03987306 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,02733905 0,03984779 ! regulation of fibroblast proliferation GO:0048145 35 22 0,000 0,02733905 0,03982256 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,02733905 0,03979735 ! viral genome replication GO:0019079 29 22 0,000 0,02733905 0,03977218 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,02733905 0,03974704 ! leukocyte adhesion GO:0007159 38 22 0,000 0,02733905 0,03972193 ! molting cycle process GO:0022404 40 22 0,000 0,02733905 0,03969686 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,02733905 0,03967181 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,02733905 0,0396468 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,02733905 0,03962181 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,02733905 0,03959686 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,02733905 0,03957194 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,02733905 0,03954706 GO:0010810|regulation of cell-substrate adhesion, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,02733905 0,0395222 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,02733905 0,03949737 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,02733905 0,03947258 ! lysosome organization GO:0007040 37 22 0,000 0,02733905 0,03944782 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,02733905 0,03942308 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,02733905 0,03939838 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,02733905 0,03937371 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,02733905 0,03934907 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,02733905 0,03932446 ! membrane depolarization GO:0051899 35 22 0,000 0,02733905 0,03929989 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,02733905 0,03927534 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,02733905 0,03925082 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,02733905 0,03922634 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,02733905 0,03920188 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,02733905 0,03917746 ! blastocyst development GO:0001824 37 22 0,000 0,02733905 0,03915306 ! neural tube closure GO:0001843 33 22 0,000 0,02733905 0,0391287 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,02733905 0,03910436 ! protein tetramerization GO:0051262 39 22 0,000 0,02733905 0,03908006 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,02856463 0,04080661 ! neuron fate commitment GO:0048663 32 23 0,000 0,02856463 0,04078128 ! embryonic pattern specification GO:0009880 31 23 0,000 0,02856463 0,04075598 ! positive regulation of cell adhesion GO:0045785 37 23 0,000 0,02856463 0,04073071 ! myelination GO:0042552 35 23 0,000 0,02856463 0,04070548 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,02856463 0,04068027 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,02856463 0,0406551 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,02856463 0,04062996 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,02856463 0,04060485 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,02856463 0,04057977 ! vesicle targeting GO:0006903 32 23 0,000 0,02856463 0,04055472 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,02856463 0,0405297 ! osteoblast differentiation GO:0001649 40 23 0,000 0,02856463 0,04050471 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,02856463 0,04047975 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,02856463 0,04045483 ! interaction with host GO:0051701 37 23 0,000 0,02856463 0,04042993 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,02856463 0,04040507 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,02856463 0,04038023 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,02856463 0,04035543 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,02856463 0,04033066 ! negative regulation of phosphorylation GO:0042326 41 23 0,000 0,02856463 0,04030591 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,02856463 0,0402812 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,02856463 0,04025652 ! cell fate determination GO:0001709 45 23 0,000 0,02856463 0,04023187 ! pentose metabolic process GO:0019321 31 23 0,000 0,02856463 0,04020725 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,02856463 0,04018266 ! spermatid development GO:0007286 33 23 0,000 0,02856463 0,04015809 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,02856463 0,04013356 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,02856463 0,04010906 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,02856463 0,04008459 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,02856463 0,04006015 ! telomere organization GO:0032200 32 23 0,000 0,02856463 0,04003574 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,02856463 0,04001135 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,02856463 0,039987 ! regulation of amine transport GO:0051952 38 23 0,000 0,02856463 0,03996268 ! liver development GO:0001889 40 23 0,000 0,02856463 0,03993838 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,02978873 0,04162459 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,02978873 0,04159932 ! initiation of viral infection GO:0019059 42 24 0,000 0,02978873 0,04157407 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,02978873 0,04154886 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,02978873 0,04152368 ! superoxide metabolic process GO:0006801 32 24 0,000 0,02978873 0,04149853 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,02978873 0,04147341 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! insulin receptor signaling pathway GO:0008286 40 24 0,000 0,02978873 0,04144832 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,02978873 0,04142326 ! sperm motility GO:0030317 27 24 0,000 0,02978873 0,04139823 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,02978873 0,04137323 ! vacuole organization GO:0007033 39 24 0,000 0,02978873 0,04134826 ! receptor metabolic process GO:0043112 37 24 0,000 0,02978873 0,04132333 ! neural crest cell development GO:0014032 39 24 0,000 0,02978873 0,04129842 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,02978873 0,04127354 ! primary neural tube formation GO:0014020 35 24 0,000 0,02978873 0,04124869 ! negative regulation of cell development GO:0010721 56 24 0,000 0,02978873 0,04122387 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,02978873 0,04119908 ! base-excision repair GO:0006284 31 24 0,000 0,02978873 0,04117432 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,02978873 0,04114959 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,02978873 0,04112489 ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,02978873 0,04110022 ! glutathione metabolic process GO:0006749 29 24 0,000 0,02978873 0,04107558 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,02978873 0,04105097 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,02978873 0,04102639 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,02978873 0,04100184 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,03101136 0,04265916 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,03101136 0,04263366 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,03101136 0,0426082 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,03101136 0,04258276 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,03101136 0,04255735 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,03101136 0,04253197 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 0,000 0,03101136 0,04250663 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,03101136 0,04248131 ! peptide transport GO:0015833 43 25 0,000 0,03101136 0,04245602 ! male gonad development GO:0008584 33 25 0,000 0,03101136 0,04243077 ! iron ion homeostasis GO:0055072 39 25 0,000 0,03101136 0,04240554 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,03101136 0,04238034 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,03101136 0,04235518 ! phospholipid transport GO:0015914 35 25 0,000 0,03101136 0,04233004 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,03101136 0,04230493 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,03101136 0,04227986 ! detection of light stimulus GO:0009583 30 25 0,000 0,03101136 0,04225481 ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,03101136 0,04222979 ! leukocyte proliferation GO:0070661 39 25 0,000 0,03101136 0,0422048 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,03101136 0,04217985 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,03223251 0,04381488 ! translational initiation GO:0006413 43 26 0,000 0,03223251 0,043789 ! regulation of pH GO:0006885 36 26 0,000 0,03223251 0,04376315 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 0,000 0,03223251 0,04373733 ! circadian rhythm GO:0007623 42 26 0,000 0,03223251 0,04371155 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,03223251 0,04368579 ! post-embryonic development GO:0009791 42 26 0,000 0,03223251 0,04366006 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,03223251 0,04363436 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,03223251 0,0436087 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,03223251 0,04358306 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,03223251 0,04355745 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,03223251 0,04353187 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,03223251 0,04350633 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,03223251 0,04348081 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,03223251 0,04345532 ! regulation of coagulation GO:0050818 39 26 0,000 0,03223251 0,04342987 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,0334522 0,04504688 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,0334522 0,04502052 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,0334522 0,04499419 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,0334522 0,04496789 ! membrane docking GO:0022406 39 27 0,000 0,0334522 0,04494163 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,0334522 0,04491539 ! catechol metabolic process GO:0009712 43 27 0,000 0,0334522 0,04488919 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,0334522 0,04486301 ! acute-phase response GO:0006953 42 27 0,000 0,0334522 0,04483687 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,0334522 0,04481075 ! myofibril assembly GO:0030239 36 27 0,000 0,0334522 0,04478467 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,0334522 0,04475862 ! response to ionizing radiation GO:0010212 47 27 0,000 0,0334522 0,0447326 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,0334522 0,0447066 ! natural killer cell activation GO:0030101 35 27 0,000 0,0334522 0,04468064 ! lipid oxidation GO:0034440 38 27 0,000 0,0334522 0,04465471 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,0334522 0,04462881 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,0334522 0,04460294 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,0334522 0,04457709 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,0334522 0,04455128 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,0334522 0,0445255 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,0334522 0,04449975 ! gene silencing GO:0016458 41 27 0,000 0,0334522 0,04447403 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,03467042 0,046067 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,03467042 0,0460404 ! phenol metabolic process GO:0018958 44 28 0,000 0,03467042 0,04601383 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,03467042 0,0459873 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,03467042 0,04596079 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,03467042 0,04593432 ! cell junction assembly GO:0034329 56 28 0,000 0,03467042 0,04590787 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,03467042 0,04588146 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,03467042 0,04585507 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,03467042 0,04582872 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,03467042 0,0458024 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,03467042 0,0457761 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,03467042 0,04574984 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,03467042 0,04572361 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,03467042 0,04569741 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,03467042 0,04567123 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,03467042 0,04564509 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,03467042 0,04561898 ! mesoderm formation GO:0001707 46 28 0,000 0,03467042 0,0455929 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,03467042 0,04556684 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,03467042 0,04554082 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,03467042 0,04551483 ! ensheathment of neurons GO:0007272 43 28 0,000 0,03467042 0,04548886 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,03467042 0,04546293 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,03467042 0,04543702 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,03467042 0,04541115 ! neural tube formation GO:0001841 41 28 0,000 0,03467042 0,0453853 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,03467042 0,04535948 ! placenta development GO:0001890 37 28 0,000 0,03467042 0,0453337 ! regulation of B cell activation GO:0050864 42 28 0,000 0,03467042 0,04530794 ! regulation of innate immune response GO:0045088 38 29 0,000 0,03588718 0,04687139 ! ovulation cycle process GO:0022602 41 29 0,000 0,03588718 0,04684479 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,03588718 0,04681821 ! protein targeting to membrane GO:0006612 53 29 0,000 0,03588718 0,04679167 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,03588718 0,04676516 ! mismatch repair GO:0006298 34 29 0,000 0,03588718 0,04673868 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,03588718 0,04671223 ! muscle cell development GO:0055001 38 29 0,000 0,03588718 0,04668581 ! formation of primary germ layer GO:0001704 48 29 0,000 0,03588718 0,04665942 ! telencephalon development GO:0021537 52 29 0,000 0,03588718 0,04663306 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,03588718 0,04660673 ! eye morphogenesis GO:0048592 51 29 0,000 0,03588718 0,04658042 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,03588718 0,04655415 ! tissue homeostasis GO:0001894 42 29 0,000 0,03588718 0,04652791 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,03710247 0,04807644 ! organic anion transport GO:0015711 51 30 0,000 0,03710247 0,04804937 ! cholesterol transport GO:0030301 46 30 0,000 0,03710247 0,04802233 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,03710247 0,04799532 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,03710247 0,04796834 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,03710247 0,04794139 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,03710247 0,04791448 ! ceramide metabolic process GO:0006672 43 30 0,000 0,03710247 0,04788759 ! ovulation cycle GO:0042698 43 30 0,000 0,03710247 0,04786073 ! hindbrain development GO:0030902 45 30 0,000 0,03710247 0,0478339 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,03710247 0,04780711 ! adult locomotory behavior GO:0008344 47 30 0,000 0,03710247 0,04778034 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,03710247 0,0477536 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,03710247 0,04772689 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,03710247 0,04770021 ! response to heat GO:0009408 41 30 0,000 0,03710247 0,04767357 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,03710247 0,04764695 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,03710247 0,04762036 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,0383163 0,04915086 ! negative regulation of secretion GO:0051048 49 31 0,000 0,0383163 0,04912346 ! mammary gland development GO:0030879 57 31 0,000 0,0383163 0,04909609 ! glial cell differentiation GO:0010001 55 31 0,000 0,0383163 0,04906876 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,0383163 0,04904145 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,0383163 0,04901418 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,0383163 0,04898693 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,0383163 0,04895972 ! segmentation GO:0035282 41 31 0,000 0,0383163 0,04893253 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,0383163 0,04890538 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,0383163 0,04887825 ! metanephros development GO:0001656 58 31 0,000 0,0383163 0,04885116 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,0383163 0,04882409 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,0383163 0,04879706 ! cell fate specification GO:0001708 37 31 0,000 0,0383163 0,04877006 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,0383163 0,04874308 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,0383163 0,04871614 ! RNA modification GO:0009451 40 31 0,000 0,0383163 0,04868922 ! regulation of muscle development GO:0048634 48 32 0,000 0,03952867 0,05020206 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,03952867 0,05017436 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,03952867 0,05014668 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,03952867 0,05011904 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,03952867 0,05009143 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,03952867 0,05006384 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,03952867 0,05003629 ! peripheral nervous system development GO:0007422 53 32 0,000 0,03952867 0,05000877 ! regulation of protein stability GO:0031647 48 32 0,000 0,03952867 0,04998127 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,03952867 0,04995381 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,03952867 0,04992638 ! cytokine production GO:0001816 44 32 0,000 0,03952867 0,04989898 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,03952867 0,04987161 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,03952867 0,04984426 ! vesicle localization GO:0051648 47 32 0,000 0,03952867 0,04981695 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,04073958 0,05131491 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,04073958 0,05128682 ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,04073958 0,05125877 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,04073958 0,05123074 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,04073958 0,05120275 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,04073958 0,05117478 ! ear morphogenesis GO:0042471 42 33 0,000 0,04073958 0,05114685 ! actomyosin structure organization GO:0031032 43 33 0,000 0,04073958 0,05111895 ! cell junction organization GO:0034330 63 33 0,000 0,04073958 0,05109107 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,04073958 0,05106323 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,04073958 0,05103542 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,04073958 0,05100764 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 0,000 0,04073958 0,05097988 ! female gonad development GO:0008585 49 33 0,000 0,04073958 0,05095216 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,04073958 0,05092447 ! positive regulation of cell development GO:0010720 54 33 0,000 0,04073958 0,05089681 ! lipid homeostasis GO:0055088 55 33 0,000 0,04073958 0,05086918 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,04073958 0,05084158 ! regulation of proteolysis GO:0030162 50 33 0,000 0,04073958 0,05081401 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,04073958 0,05078647 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,04073958 0,05075895 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,04073958 0,05073147 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,04073958 0,05070402 ! mRNA catabolic process GO:0006402 48 34 0,000 0,04194903 0,05218105 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,04194903 0,05215285 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,04194903 0,05212467 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,04194903 0,05209653 ! feeding behavior GO:0007631 45 34 0,000 0,04194903 0,05206841 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,04194903 0,05204033 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,04194903 0,05201227 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,04194903 0,05198425 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,04194903 0,05195626 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,04194903 0,05192829 ! neuron migration GO:0001764 46 34 0,000 0,04194903 0,05190036 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,04194903 0,05187246 ! female gamete generation GO:0007292 43 34 0,000 0,04194903 0,05184458 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,04194903 0,05181674 ! polyol metabolic process GO:0019751 44 34 0,000 0,04194903 0,05178893 ! aerobic respiration GO:0009060 47 34 0,000 0,04194903 0,05176114 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,04194903 0,05173339 ! cellular response to insulin stimulus GO:0032869 52 34 0,000 0,04194903 0,05170566 ! embryonic organ development GO:0048568 45 34 0,000 0,04194903 0,05167797 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,04194903 0,0516503 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,04315703 0,05310923 ! Notch signaling pathway GO:0007219 56 35 0,000 0,04315703 0,05308083 ! regulation of intracellular protein transport GO:0033157 59 35 0,000 0,04315703 0,05305246 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,04315703 0,05302412 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,04315703 0,05299581 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,04315703 0,05296753 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,04315703 0,05293929 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,04315703 0,05291107 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,04315703 0,05288288 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,04315703 0,05285472 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,04315703 0,05282659 ! glycogen metabolic process GO:0005977 48 35 0,000 0,04315703 0,05279849 ! pigment metabolic process GO:0042440 61 35 0,000 0,04315703 0,05277042 ! positive regulation of leukocyte proliferation GO:0070665 50 35 0,000 0,04315703 0,05274238 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! protein homooligomerization GO:0051260 52 35 0,000 0,04315703 0,05271437 ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,04436357 0,05415935 GO:0090047|positive regulation of transcription regulator activity, ! regulation of hormone secretion GO:0046883 48 36 0,000 0,04436357 0,05413061 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,04436357 0,05410191 ! negative regulation of binding GO:0051100 58 36 0,000 0,04436357 0,05407324 ! organic ether metabolic process GO:0018904 46 36 0,000 0,04436357 0,0540446 ! neural tube development GO:0021915 50 36 0,000 0,04436357 0,05401599 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,04436357 0,05398741 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,04436357 0,05395886 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,04436357 0,05393034 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,04436357 0,05390185 ! glucan metabolic process GO:0044042 49 36 0,000 0,04436357 0,05387339 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,04556866 0,05530761 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,04556866 0,05527844 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,04556866 0,0552493 ! learning GO:0007612 67 37 0,000 0,04556866 0,05522019 ! ion transmembrane transport GO:0034220 56 37 0,000 0,04556866 0,05519111 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,04556866 0,05516206 ! regulation of protein secretion GO:0050708 51 37 0,000 0,04556866 0,05513304 ! amino acid activation GO:0043038 52 37 0,000 0,04556866 0,05510406 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,04556866 0,0550751 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,0467723 0,05650015 ! gliogenesis GO:0042063 71 38 0,000 0,0467723 0,05647049 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,0467723 0,05644086 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,0467723 0,05641127 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,0467723 0,0563817 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,0467723 0,05635217 ! phagocytosis GO:0006909 60 38 0,000 0,0467723 0,05632266 ! mesenchymal cell development GO:0014031 64 38 0,000 0,0467723 0,05629319 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 0,000 0,0467723 0,05626375 ! maintenance of location in cell GO:0051651 69 38 0,000 0,0467723 0,05623434 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,04797449 0,05764959 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,04797449 0,05761949 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,04797449 0,05758942 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,04797449 0,05755938 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,04797449 0,05752937 ! regulation of epithelial cell proliferation GO:0050678 71 39 0,000 0,04797449 0,05749939 ! male sex differentiation GO:0046661 53 39 0,000 0,04797449 0,05746944 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,04797449 0,05743952 ! chromatin remodeling GO:0006338 68 39 0,000 0,04797449 0,05740964 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,04797449 0,05737978 ! JNK cascade GO:0007254 54 39 0,000 0,04797449 0,05734996 ! developmental growth GO:0048589 62 39 0,000 0,04797449 0,05732017 ! cell growth GO:0016049 61 39 0,000 0,04797449 0,05729041 ! synapse organization GO:0050808 55 39 0,000 0,04797449 0,05726068 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,04917523 0,0586634 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,04917523 0,05863299 ! regulation of tube size GO:0035150 60 40 0,000 0,04917523 0,05860261 GO:0050880|regulation of blood vessel size, ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,04917523 0,05857226 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,04917523 0,05854194 ! peptide metabolic process GO:0006518 56 40 0,000 0,04917523 0,05851166 ! induction of apoptosis by intracellular signals GO:0008629 67 40 0,000 0,04917523 0,0584814 ! inner ear development GO:0048839 57 40 0,000 0,04917523 0,05845118 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,04917523 0,05842099 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,04917523 0,05839083 ! double-strand break repair GO:0006302 67 40 0,000 0,04917523 0,0583607 ! B cell differentiation GO:0030183 62 40 0,000 0,04917523 0,0583306 ! epidermal cell differentiation GO:0009913 53 40 0,000 0,04917523 0,05830053 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,04917523 0,0582705 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,04917523 0,05824049 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,04917523 0,05821052 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,05037453 0,05959949 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,05037453 0,05956885 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,05037453 0,05953824 ! glucose transport GO:0015758 52 41 0,000 0,05037453 0,05950766 ! endosome transport GO:0016197 71 41 0,000 0,05037453 0,05947711 ! striated muscle contraction GO:0006941 62 41 0,000 0,05037453 0,0594466 ! positive regulation of DNA binding GO:0043388 57 41 0,000 0,05037453 0,05941611 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,05037453 0,05938566 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,05037453 0,05935523 ! biopolymer methylation GO:0043414 62 41 0,000 0,05037453 0,05932484 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,05037453 0,05929448 ! mitochondrial transport GO:0006839 60 42 0,000 0,05157238 0,06067339 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,05157238 0,06064237 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 0,000 0,05157238 0,06061138 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,05157238 0,06058043 ! cellular component disassembly GO:0022411 64 42 0,000 0,05157238 0,0605495 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,05157238 0,06051861 ! hexose transport GO:0008645 54 42 0,000 0,05157238 0,06048775 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,05157238 0,06045692 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,05157238 0,06042612 ! excretion GO:0007588 63 42 0,000 0,05157238 0,06039536 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,05157238 0,06036462 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,05157238 0,06033392 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,05157238 0,06030324 ! positive regulation of binding GO:0051099 59 43 0,000 0,05276879 0,06167085 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,05276879 0,06163952 ! leukocyte migration GO:0050900 60 43 0,000 0,05276879 0,06160824 ! neuromuscular process GO:0050905 79 43 0,000 0,05276879 0,06157698 ! activation of caspase activity GO:0006919 65 43 0,000 0,05276879 0,06154575 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,05276879 0,06151456 ! tRNA processing GO:0008033 49 43 0,000 0,05276879 0,0614834 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,05276879 0,06145227 ! vesicle organization GO:0016050 79 43 0,000 0,05276879 0,06142117 ! response to insulin stimulus GO:0032868 63 43 0,000 0,05276879 0,0613901 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,05276879 0,06135906 ! methylation GO:0032259 64 43 0,000 0,05276879 0,06132806 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,05396376 0,06268518 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,05396376 0,06265354 ! glycolysis GO:0006096 53 44 0,000 0,05396376 0,06262193 ! regulation of action potential GO:0001508 71 44 0,000 0,05396376 0,06259035 ! regulation of ion transport GO:0043269 57 44 0,000 0,05396376 0,0625588 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,05396376 0,06252728 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,05396376 0,0624958 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,05396376 0,06246435 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,05396376 0,06243293 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,05396376 0,06240154 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,05396376 0,06237018 ! regulation of mast cell proliferation GO:0070666 64 44 0,000 0,05396376 0,06233885 ! RNA catabolic process GO:0006401 64 45 0,000 0,05515729 0,06368563 ! positive regulation of defense response GO:0031349 59 45 0,000 0,05515729 0,06365368 ! regulation of translational initiation GO:0006446 64 45 0,000 0,05515729 0,06362175 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,05515729 0,06358986 ! cell recognition GO:0008037 58 45 0,000 0,05515729 0,063558 ! cell maturation GO:0048469 60 45 0,000 0,05515729 0,06352618 ! protein amino acid autophosphorylation GO:0046777 80 45 0,000 0,05515729 0,06349438 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,05634939 0,06483421 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,05634939 0,0648018 ! cell redox homeostasis GO:0045454 63 46 0,000 0,05634939 0,06476941 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,05634939 0,06473706 ! regulation of ossification GO:0030278 71 46 0,000 0,05634939 0,06470474 ! histone modification GO:0016570 68 46 0,000 0,05634939 0,06467245 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,05634939 0,0646402 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,05754005 0,06597313 ! viral infectious cycle GO:0019058 71 47 0,000 0,05754005 0,06594026 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,05754005 0,06590742 ! endocrine system development GO:0035270 83 47 0,000 0,05754005 0,06587462 ! covalent chromatin modification GO:0016569 75 47 0,000 0,05754005 0,06584184 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,05754005 0,0658091 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,05754005 0,0657764 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,05754005 0,06574372 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,05754005 0,06571108 ! regulation of leukocyte proliferation GO:0070663 71 47 0,000 0,05754005 0,06567846 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,05754005 0,06564589 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,05754005 0,06561334 ! chloride transport GO:0006821 67 48 0,000 0,05872927 0,06693623 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,05872927 0,06690308 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 0,000 0,05872927 0,06686996 ! response to temperature stimulus GO:0009266 62 48 0,000 0,05872927 0,06683687 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,05872927 0,06680382 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,05872927 0,0667708 ! gastrulation GO:0007369 73 48 0,000 0,05872927 0,06673781 ! heart morphogenesis GO:0003007 65 48 0,000 0,05872927 0,06670485 ! regulation of DNA replication GO:0006275 75 48 0,000 0,05872927 0,06667193 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,05872927 0,06663903 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,05872927 0,06660617 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,05872927 0,06657335 ! regulation of endocytosis GO:0030100 63 48 0,000 0,05872927 0,06654055 ! nuclear export GO:0051168 69 48 0,000 0,05872927 0,06650779 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,05872927 0,06647506 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,05872927 0,06644236 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,05991706 0,06775282 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,05991706 0,06771953 ! sensory perception of smell GO:0007608 61 49 0,000 0,05991706 0,06768627 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,05991706 0,06765304 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,05991706 0,06761984 ! RNA elongation GO:0006354 62 49 0,000 0,05991706 0,06758668 ! regulation of intracellular transport GO:0032386 78 49 0,000 0,05991706 0,06755355 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,05991706 0,06752045 ! germ cell development GO:0007281 68 49 0,000 0,05991706 0,06748739 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,05991706 0,06745435 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,05991706 0,06742135 ! cartilage development GO:0051216 70 49 0,000 0,05991706 0,06738838 ! maintenance of location GO:0051235 84 49 0,000 0,05991706 0,06735545 ! regulation of actin filament length GO:0030832 72 50 0,000 0,06110342 0,06865553 ! ear development GO:0043583 72 50 0,000 0,06110342 0,06862201 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,06110342 0,06858852 ! membrane fusion GO:0006944 80 50 0,000 0,06110342 0,06855506 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,06110342 0,06852163 ! lipid modification GO:0030258 73 50 0,000 0,06110342 0,06848824 ! positive regulation of growth GO:0045927 67 50 0,000 0,06110342 0,06845488 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,06110342 0,06842155 ! proton transport GO:0015992 75 50 0,000 0,06110342 0,06838826 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,06110342 0,068355 ! positive regulation of secretion GO:0051047 71 51 0,000 0,06228835 0,06964668 ! hydrogen transport GO:0006818 77 51 0,000 0,06228835 0,06961283 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,06228835 0,06957903 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 0,000 0,06228835 0,06954525 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,06228835 0,06951151 ! adult behavior GO:0030534 80 51 0,000 0,06228835 0,0694778 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,06228835 0,06944412 ! transition metal ion transport GO:0000041 74 52 0,000 0,06347186 0,0707293 ! regulation of cellular component size GO:0032535 74 52 0,000 0,06347186 0,07069505 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,06347186 0,07066083 ! aging GO:0007568 79 52 0,000 0,06347186 0,07062664 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,06347186 0,07059249 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,06347186 0,07055837 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,06465394 0,07183771 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,06465394 0,07180302 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,06465394 0,07176836 ! kidney development GO:0001822 90 53 0,000 0,06465394 0,07173374 ! single fertilization GO:0007338 59 53 0,000 0,06465394 0,07169916 ! cell projection assembly GO:0030031 76 53 0,000 0,06465394 0,0716646 ! amino acid transport GO:0006865 84 54 0,000 0,06583459 0,07293813 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,06583459 0,07290301 ! glucose catabolic process GO:0006007 66 54 0,000 0,06583459 0,07286793 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,06583459 0,07283288 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,06583459 0,07279786 ! DNA catabolic process GO:0006308 67 54 0,000 0,06583459 0,07276288 ! detection of external stimulus GO:0009581 66 54 0,000 0,06583459 0,07272793 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,06583459 0,07269302 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,06583459 0,07265814 ! exocytosis GO:0006887 74 55 0,000 0,06701382 0,07392412 ! mesoderm development GO:0007498 76 55 0,000 0,06701382 0,07388868 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,06701382 0,07385328 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,06701382 0,07381791 ! DNA damage response, signal transduction GO:0042770 96 56 0,000 0,06819163 0,07507934 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,06819163 0,07504342 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,06819163 0,07500753 ! negative regulation of protein kinase activity GO:0006469 99 57 0,000 0,06936802 0,07626503 ! carbohydrate transport GO:0008643 74 57 0,000 0,06936802 0,07622859 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,06936802 0,07619219 GO:0048609|reproductive process in a multicellular organism, ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,06936802 0,07615582 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,06936802 0,07611949 ! camera-type eye development GO:0043010 88 57 0,000 0,06936802 0,07608319 ! secondary metabolic process GO:0019748 84 57 0,000 0,06936802 0,07604693 ! developmental maturation GO:0021700 75 57 0,000 0,06936802 0,0760107 ! gonad development GO:0008406 79 57 0,000 0,06936802 0,0759745 ! negative regulation of kinase activity GO:0033673 100 58 0,000 0,07054299 0,0772246 ! viral reproductive process GO:0022415 87 58 0,000 0,07054299 0,07718786 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,07054299 0,07715116 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,07054299 0,07711449 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,07054299 0,07707786 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,07171655 0,07832292 ! activation of MAPK activity GO:0000187 84 59 0,000 0,07171655 0,07828575 ! actin filament organization GO:0007015 95 59 0,000 0,07171655 0,07824861 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,07171655 0,07821151 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,07171655 0,07817444 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,07288869 0,07941449 ! phosphoinositide metabolic process GO:0030384 87 60 0,000 0,07288869 0,07937689 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,07288869 0,07933933 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,07288869 0,0793018 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,07288869 0,0792643 ! regulation of heart contraction GO:0008016 91 60 0,000 0,07288869 0,07922684 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,07288869 0,07918942 ! fertilization GO:0009566 68 60 0,000 0,07288869 0,07915203 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,07405942 0,0803854 ! cell-matrix adhesion GO:0007160 114 61 0,000 0,07405942 0,08034749 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,07405942 0,08030961 ! urogenital system development GO:0001655 101 61 0,000 0,07405942 0,08027176 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,07405942 0,08023395 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,07405942 0,08019617 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,07405942 0,08015843 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! negative regulation of transferase activity GO:0051348 105 61 0,000 0,07405942 0,08012073 ! amine catabolic process GO:0009310 90 62 0,000 0,07522874 0,08134749 ! neurotransmitter transport GO:0006836 81 62 0,000 0,07522874 0,08130926 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,07522874 0,08127107 ! negative regulation of cell growth GO:0030308 106 62 0,000 0,07522874 0,08123291 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,07522874 0,08119479 ! regulation of transcription factor activity GO:0051090 97 63 0,000 0,07639665 0,08241665 GO:0090046|regulation of transcription regulator activity, ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,07639665 0,08237801 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 0,000 0,07639665 0,08233941 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 0,000 0,07639665 0,08230084 ! viral reproduction GO:0016032 92 63 0,000 0,07639665 0,08226231 ! regulation of lipase activity GO:0060191 109 63 0,000 0,07639665 0,08222382 ! cell cycle checkpoint GO:0000075 108 64 0,000 0,07756315 0,08344025 ! negative regulation of cell size GO:0045792 108 64 0,000 0,07756315 0,08340124 ! appendage morphogenesis GO:0035107 93 64 0,000 0,07756315 0,08336226 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,07756315 0,08332333 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,07756315 0,08328443 ! hexose catabolic process GO:0019320 82 64 0,000 0,07756315 0,08324556 ! reproductive structure development GO:0048608 90 65 0,000 0,07872824 0,08445661 ! regulation of caspase activity GO:0043281 97 65 0,000 0,07872824 0,08441723 ! appendage development GO:0048736 94 65 0,000 0,07872824 0,08437789 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 0,000 0,07872824 0,08433859 ! defense response to bacterium GO:0042742 73 65 0,000 0,07872824 0,08429933 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,07872824 0,0842601 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,07872824 0,08422091 ! activation of immune response GO:0002253 83 65 0,000 0,07872824 0,08418176 ! protein oligomerization GO:0051259 100 65 0,000 0,07872824 0,08414264 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,07989193 0,0853467 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,07989193 0,08530708 ! antigen processing and presentation GO:0019882 96 66 0,000 0,07989193 0,08526749 ! axon guidance GO:0007411 99 66 0,000 0,07989193 0,08522794 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,07989193 0,08518843 ! regulation of immune effector process GO:0002697 101 66 0,000 0,07989193 0,08514896 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,08105422 0,08634771 ! regulation of endopeptidase activity GO:0052548 99 67 0,000 0,08105422 0,08630773 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,08105422 0,0862678 ! acute inflammatory response GO:0002526 92 68 0,000 0,0822151 0,08746288 ! learning or memory GO:0007611 123 68 0,000 0,0822151 0,08742244 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,0822151 0,08738204 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,0822151 0,08734168 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,0822151 0,08730136 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,0822151 0,08726107 ! rhythmic process GO:0048511 105 68 0,000 0,0822151 0,08722082 ! inorganic anion transport GO:0015698 93 68 0,000 0,0822151 0,08718061 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,08337459 0,08836938 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,08337459 0,08832868 ! response to drug GO:0042493 108 69 0,000 0,08337459 0,08828801 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,08453268 0,08947315 ! humoral immune response GO:0006959 86 70 0,000 0,08453268 0,08943199 ! eye development GO:0001654 111 70 0,000 0,08453268 0,08939088 ! amine transport GO:0015837 101 70 0,000 0,08453268 0,0893498 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,08453268 0,08930875 ! regulation of catabolic process GO:0009894 106 70 0,000 0,08453268 0,08926775 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,08568937 0,0904477 ! muscle cell differentiation GO:0042692 104 71 0,000 0,08568937 0,09040621 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,08568937 0,09036476 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,08568937 0,09032335 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,08568937 0,09028197 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,08568937 0,09024063 ! regulation of peptidase activity GO:0052547 106 72 0,000 0,08684466 0,09141543 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,08684466 0,09137361 ! negative regulation of transport GO:0051051 116 73 0,000 0,08799856 0,09254535 ! regulation of blood pressure GO:0008217 107 73 0,000 0,08799856 0,09250306 ! tube morphogenesis GO:0035239 118 73 0,000 0,08799856 0,0924608 ! mitochondrion organization GO:0007005 104 73 0,000 0,08799856 0,09241858 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,08799856 0,0923764 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,08915107 0,09354355 ! digestion GO:0007586 97 74 0,000 0,08915107 0,09350089 ! protein import into nucleus GO:0006606 118 74 0,000 0,08915107 0,09345828 ! cellular response to hormone stimulus GO:0032870 109 74 0,000 0,08915107 0,0934157 ! positive regulation of lymphocyte activation GO:0051251 108 74 0,000 0,08915107 0,09337316 ! blood coagulation GO:0007596 116 75 0,000 0,09030219 0,09453575 GO:0050817|coagulation, ! negative regulation of growth GO:0045926 123 75 0,000 0,09030219 0,09449274 ! nuclear import GO:0051170 121 75 0,000 0,09030219 0,09444977 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,09030219 0,09440683 ! amine biosynthetic process GO:0009309 97 76 0,000 0,09145192 0,09556539 ! tRNA metabolic process GO:0006399 95 76 0,000 0,09145192 0,09552199 ! regulation of protein transport GO:0051223 114 76 0,000 0,09145192 0,09547863 GO:0070201|regulation of establishment of protein localization, ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,09260026 0,09663367 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,09260026 0,09658984 ! regulation of DNA binding GO:0051101 119 77 0,000 0,09260026 0,09654606 ! gland development GO:0048732 148 77 0,000 0,09260026 0,09650231 ! sex differentiation GO:0007548 105 77 0,000 0,09260026 0,09645861 ! protein ubiquitination GO:0016567 125 77 0,000 0,09260026 0,09641494 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,09260026 0,09637131 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,09260026 0,09632773 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,09260026 0,09628418 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,09374722 0,09743272 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,09374722 0,09738871 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,09489279 0,09853428 ! cellular respiration GO:0045333 107 79 0,000 0,09489279 0,09848981 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,09489279 0,09844539 ! T cell activation GO:0042110 134 79 0,000 0,09489279 0,098401 ! regulation of lyase activity GO:0051339 133 79 0,000 0,09489279 0,09835666 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,09489279 0,09831235 ! chromatin assembly GO:0031497 102 80 0,000 0,09603698 0,09945298 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,09603698 0,09940822 ! protein localization in nucleus GO:0034504 133 80 0,000 0,09603698 0,0993635 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,09603698 0,09931882 ! forebrain development GO:0030900 131 80 0,000 0,09603698 0,09927419 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,09717979 0,10041039 ! hemostasis GO:0007599 125 81 0,000 0,09717979 0,1003653 ! mRNA transport GO:0051028 121 81 0,000 0,09717979 0,10032026 ! regulation of neurological system process GO:0031644 122 81 0,000 0,09717979 0,10027525 ! vitamin metabolic process GO:0006766 103 81 0,000 0,09717979 0,10023028 ! positive regulation of cell activation GO:0050867 120 81 0,000 0,09717979 0,10018536 GO:0002696|positive regulation of leukocyte activation, ! detection of stimulus GO:0051606 108 82 0,000 0,09832123 0,10131668 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,09946128 0,10244556 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,09946128 0,10239971 ! regulation of cell adhesion GO:0030155 159 83 0,000 0,09946128 0,10235389 ! regulation of defense response GO:0031347 117 84 0,000 0,10059996 0,10347938 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,10059996 0,10343313 ! sterol metabolic process GO:0016125 120 84 0,000 0,10059996 0,10338691 ! regulation of DNA metabolic process GO:0051052 135 85 0,000 0,10173726 0,10450902 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,10173726 0,10446237 ! rRNA metabolic process GO:0016072 107 85 0,000 0,10173726 0,10441575 GO:0006364|rRNA processing, ! positive regulation of MAP kinase activity GO:0043406 121 85 0,000 0,10173726 0,10436918 ! transcription initiation GO:0006352 118 85 0,000 0,10173726 0,10432265 ! anterior/posterior pattern formation GO:0009952 124 85 0,000 0,10173726 0,10427616 ! regulation of protein localization GO:0032880 132 85 0,000 0,10173726 0,10422971 ! regulation of membrane potential GO:0042391 128 85 0,000 0,10173726 0,1041833 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,10287319 0,10529966 ! cell cycle arrest GO:0007050 150 86 0,000 0,10287319 0,10525282 ! nucleosome organization GO:0034728 114 87 0,000 0,10400775 0,10636631 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,10400775 0,10631903 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,10400775 0,1062718 ! skeletal muscle tissue development GO:0007519 123 87 0,000 0,10400775 0,10622461 GO:0060538|skeletal muscle organ development, ! female pregnancy GO:0007565 130 87 0,000 0,10400775 0,10617746 ! Wnt receptor signaling pathway GO:0016055 130 87 0,000 0,10400775 0,10613036 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,10514094 0,1072391 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,10514094 0,10719156 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,10514094 0,10714407 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,10514094 0,10709662 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 0,000 0,10514094 0,10704921 ! regulation of neurogenesis GO:0050767 153 89 0,000 0,10627276 0,10815369 ! reproductive developmental process GO:0003006 127 89 0,000 0,10627276 0,10810586 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,10627276 0,10805807 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,10627276 0,10801032 ! regulation of T cell activation GO:0050863 128 89 0,000 0,10627276 0,10796261 ! leukocyte differentiation GO:0002521 143 90 0,000 0,10740322 0,10906287 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,10740322 0,10901474 ! hormone metabolic process GO:0042445 121 90 0,000 0,10740322 0,10896665 ! RNA localization GO:0006403 135 91 0,000 0,10853231 0,11006363 ! ATP metabolic process GO:0046034 137 91 0,000 0,10853231 0,11001512 ! response to virus GO:0009615 122 91 0,000 0,10853231 0,10996665 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,10966003 0,11106036 ! glycerophospholipid metabolic process GO:0006650 130 92 0,000 0,10966003 0,11101148 ! cell fate commitment GO:0045165 141 92 0,000 0,10966003 0,11096264 ! positive regulation of immune response GO:0050778 121 92 0,000 0,10966003 0,11091384 ! DNA recombination GO:0006310 146 92 0,000 0,10966003 0,11086509 ! sulfur metabolic process GO:0006790 118 92 0,000 0,10966003 0,11081638 ! regulation of cytoskeleton organization GO:0051493 154 93 0,000 0,1107864 0,11190545 ! peptidyl-amino acid modification GO:0018193 147 93 0,000 0,1107864 0,11185633 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,1107864 0,11180724 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,1107864 0,11175821 ! electron transport chain GO:0022900 123 94 0,000 0,1119114 0,11284359 ! regulation of binding GO:0051098 151 95 0,000 0,11303505 0,11392665 ! carboxylic acid transport GO:0046942 147 95 0,000 0,11303505 0,11387674 GO:0015849|organic acid transport, ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,11415733 0,11495704 ! regulation of cellular component biogenesis GO:0044087 158 96 0,000 0,11415733 0,11490673 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,11415733 0,11485646 ! protein maturation GO:0051604 129 96 0,000 0,11415733 0,11480624 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,11527827 0,11588287 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,11527827 0,11583225 ! calcium ion transport GO:0006816 167 99 0,000 0,11751607 0,11802924 ! protein import GO:0017038 156 99 0,000 0,11751607 0,11797772 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 0,000 0,11751607 0,11792625 ! regulation of translation GO:0006417 151 100 0,000 0,11863295 0,11899511 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,11863295 0,11894323 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,11863295 0,11889141 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,11863295 0,11883963 ! divalent metal ion transport GO:0070838 171 100 0,000 0,11863295 0,11878789 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,11863295 0,1187362 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,11863295 0,11868455 ! protein localization in organelle GO:0033365 161 100 0,000 0,11863295 0,11863295