pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-b1/out-0.05-06-0.01-300-run-b1//th1-pval-1e-01-08-th2-pval-1e-02-02-th3-pval-1e-01-01-run-b1/go_data/7108-8-real-Zhang-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 2,000 1,83E-08 4,208E-05 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 2,000 5,116E-08 5,883E-05 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 2,000 1,504E-07 1,153E-04 ! regulation of endothelial cell proliferation GO:0001936 46 24 2,000 1,83E-06 1,052E-03 ! in utero embryonic development GO:0001701 147 96 3,000 2,463E-06 1,133E-03 ! tissue remodeling GO:0048771 62 36 2,000 6,406E-06 2,456E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 9,995E-06 3,284E-03 ! regulation of hormone biosynthetic process GO:0046885 7 5 1,000 9,995E-06 2,873E-03 ! embryonic hemopoiesis GO:0035162 10 5 1,000 9,995E-06 2,554E-03 ! positive regulation of glycolysis GO:0045821 11 5 1,000 9,995E-06 2,299E-03 ! positive regulation of viral genome replication GO:0045070 8 5 1,000 9,995E-06 2,09E-03 ! regulation of retroviral genome replication GO:0045091 6 5 1,000 9,995E-06 1,916E-03 ! positive regulation of chemokine production GO:0032722 7 5 1,000 9,995E-06 1,768E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 1,000 9,995E-06 1,642E-03 ! positive regulation of cell cycle GO:0045787 77 45 2,000 1,266E-05 1,941E-03 ! mRNA stabilization GO:0048255 15 6 1,000 1,498E-05 2,154E-03 GO:0043489|RNA stabilization, ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 1,000 1,498E-05 2,027E-03 ! DNA topological change GO:0006265 8 6 1,000 1,498E-05 1,914E-03 ! gas homeostasis GO:0033483 11 6 1,000 1,498E-05 1,814E-03 ! positive regulation of cell migration GO:0030335 92 51 2,000 1,851E-05 2,128E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 2,096E-05 2,296E-03 ! T-helper 1 type immune response GO:0042088 11 7 1,000 2,096E-05 2,192E-03 ! hemoglobin metabolic process GO:0020027 10 7 1,000 2,096E-05 2,096E-03 ! positive regulation of monooxygenase activity GO:0032770 11 7 1,000 2,096E-05 2,009E-03 ! positive regulation of cell motion GO:0051272 99 56 2,000 2,455E-05 2,259E-03 ! chromosome segregation GO:0007059 83 57 2,000 2,59E-05 2,291E-03 ! induction of positive chemotaxis GO:0050930 14 8 1,000 2,793E-05 2,38E-03 ! positive regulation of endothelial cell migration GO:0010595 18 8 1,000 2,793E-05 2,295E-03 ! regulation of vascular permeability GO:0043114 12 8 1,000 2,793E-05 2,215E-03 ! regulation of homeostatic process GO:0032844 105 60 2,000 3,023E-05 2,318E-03 ! positive regulation of glucose metabolic process GO:0010907 15 9 1,000 3,589E-05 2,663E-03 ! regulation of glycolysis GO:0006110 15 9 1,000 3,589E-05 2,58E-03 ! lung alveolus development GO:0048286 17 9 1,000 3,589E-05 2,502E-03 ! DNA ligation GO:0006266 14 9 1,000 3,589E-05 2,428E-03 ! regulation of hormone metabolic process GO:0032350 15 9 1,000 3,589E-05 2,359E-03 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 1,000 3,589E-05 2,293E-03 ! embryonic placenta development GO:0001892 12 9 1,000 3,589E-05 2,231E-03 ! blood vessel remodeling GO:0001974 21 10 1,000 4,484E-05 2,714E-03 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 1,000 4,484E-05 2,644E-03 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 1,000 4,484E-05 2,578E-03 ! regulation of bone resorption GO:0045124 24 10 1,000 4,484E-05 2,515E-03 ! positive regulation of leukocyte migration GO:0002687 23 10 1,000 4,484E-05 2,455E-03 ! positive regulation of viral reproduction GO:0048524 15 10 1,000 4,484E-05 2,398E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 1,000 4,484E-05 2,344E-03 GO:0043470|regulation of carbohydrate catabolic process, ! phosphoinositide-mediated signaling GO:0048015 109 71 2,000 5,014E-05 2,563E-03 ! response to hypoxia GO:0001666 132 72 2,000 5,229E-05 2,614E-03 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 1,000 5,477E-05 2,68E-03 ! regulation of positive chemotaxis GO:0050926 17 11 1,000 5,477E-05 2,624E-03 GO:0050927|positive regulation of positive chemotaxis, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 1,000 5,477E-05 2,571E-03 ! regulation of leukocyte migration GO:0002685 24 11 1,000 5,477E-05 2,519E-03 ! response to oxygen levels GO:0070482 137 74 2,000 5,676E-05 2,56E-03 ! positive regulation of cellular catabolic process GO:0031331 22 12 1,000 6,568E-05 2,905E-03 ! heart looping GO:0001947 15 12 1,000 6,568E-05 2,85E-03 ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 1,000 6,568E-05 2,798E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of mRNA stability GO:0043488 27 12 1,000 6,568E-05 2,747E-03 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 1,000 6,568E-05 2,698E-03 ! regulation of chemokine production GO:0032642 17 13 1,000 7,758E-05 3,13E-03 ! regulation of monooxygenase activity GO:0032768 26 13 1,000 7,758E-05 3,076E-03 ! regulation of RNA stability GO:0043487 28 13 1,000 7,758E-05 3,024E-03 ! negative regulation of bone remodeling GO:0046851 26 14 1,000 9,045E-05 3,467E-03 ! regulation of erythrocyte differentiation GO:0045646 27 14 1,000 9,045E-05 3,411E-03 ! muscle maintenance GO:0046716 19 14 1,000 9,045E-05 3,356E-03 ! epithelial to mesenchymal transition GO:0001837 22 14 1,000 9,045E-05 3,302E-03 ! negative regulation of cell cycle process GO:0010948 24 15 1,000 1,043E-04 3,748E-03 ! positive regulation of oxidoreductase activity GO:0051353 21 15 1,000 1,043E-04 3,691E-03 ! negative regulation of tissue remodeling GO:0034104 27 15 1,000 1,043E-04 3,635E-03 ! regulation of glucose metabolic process GO:0010906 22 16 1,000 1,191E-04 4,09E-03 ! cellular response to unfolded protein GO:0034620 19 16 1,000 1,191E-04 4,03E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 1,000 1,191E-04 3,971E-03 ! neural crest cell migration GO:0001755 24 16 1,000 1,191E-04 3,914E-03 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 1,000 1,191E-04 3,859E-03 ! regulation of viral genome replication GO:0045069 24 17 1,000 1,349E-04 4,31E-03 ! negative regulation of homeostatic process GO:0032845 28 17 1,000 1,349E-04 4,251E-03 ! positive regulation of angiogenesis GO:0045766 35 18 1,000 1,517E-04 4,715E-03 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 1,000 1,517E-04 4,652E-03 ! regulation of carbohydrate metabolic process GO:0006109 28 19 1,000 1,695E-04 5,128E-03 GO:0010675|regulation of cellular carbohydrate metabolic process, ! apoptotic nuclear changes GO:0030262 24 19 1,000 1,695E-04 5,062E-03 ! regulation of endothelial cell migration GO:0010594 40 19 1,000 1,695E-04 4,997E-03 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 1,000 1,695E-04 4,934E-03 ! chromosome condensation GO:0030261 31 20 1,000 1,882E-04 5,41E-03 ! positive regulation of locomotion GO:0040017 35 20 1,000 1,882E-04 5,343E-03 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! regulation of chemotaxis GO:0050920 36 21 1,000 2,078E-04 5,83E-03 ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 2,078E-04 5,76E-03 ! cholesterol biosynthetic process GO:0006695 29 21 1,000 2,078E-04 5,691E-03 ! vasculogenesis GO:0001570 33 22 1,000 2,285E-04 6,183E-03 ! regulation of behavior GO:0050795 38 22 1,000 2,285E-04 6,111E-03 ! cellular iron ion homeostasis GO:0006879 37 23 1,000 2,501E-04 6,612E-03 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 2,501E-04 6,537E-03 ! regulation of viral reproduction GO:0050792 32 23 1,000 2,501E-04 6,463E-03 ! cellular response to oxidative stress GO:0034599 33 23 1,000 2,501E-04 6,392E-03 ! regulation of cellular catabolic process GO:0031329 36 24 1,000 2,727E-04 6,892E-03 ! fat cell differentiation GO:0045444 37 24 1,000 2,727E-04 6,817E-03 ! neural crest cell development GO:0014032 39 24 1,000 2,727E-04 6,744E-03 GO:0014033|neural crest cell differentiation, ! base-excision repair GO:0006284 31 24 1,000 2,727E-04 6,672E-03 ! regulation of oxidoreductase activity GO:0051341 39 24 1,000 2,727E-04 6,602E-03 ! iron ion homeostasis GO:0055072 39 25 1,000 2,962E-04 7,097E-03 ! regulation of chromosome organization GO:0033044 35 25 1,000 2,962E-04 7,023E-03 ! positive regulation of nuclear division GO:0051785 39 25 1,000 2,962E-04 6,952E-03 GO:0045840|positive regulation of mitosis, ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 1,000 3,207E-04 7,45E-03 ! sterol biosynthetic process GO:0016126 40 28 1,000 3,725E-04 8,568E-03 ! positive regulation of catabolic process GO:0009896 40 28 1,000 3,725E-04 8,483E-03 ! placenta development GO:0001890 37 28 1,000 3,725E-04 8,4E-03 ! collagen metabolic process GO:0032963 40 30 1,000 4,282E-04 9,561E-03 ! spindle organization GO:0007051 37 30 1,000 4,282E-04 9,47E-03 ! positive regulation of gene-specific transcription GO:0043193 47 31 1,000 4,574E-04 0,01002008 ! mitotic sister chromatid segregation GO:0000070 45 32 1,000 4,876E-04 0,0105808 ! meiosis I GO:0007127 52 32 1,000 4,876E-04 0,01048192 ! sister chromatid segregation GO:0000819 46 33 1,000 5,188E-04 0,01104812 ! carbohydrate homeostasis GO:0033500 39 33 1,000 5,188E-04 0,01094676 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 1,000 5,188E-04 0,01084724 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 1,000 5,188E-04 0,01074952 ! cytokinesis GO:0000910 52 33 1,000 5,188E-04 0,01065354 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 1,000 5,509E-04 0,01121238 ! embryonic organ development GO:0048568 45 34 1,000 5,509E-04 0,01111402 ! mesenchymal cell development GO:0014031 64 38 1,000 6,886E-04 0,01377246 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! multicellular organismal metabolic process GO:0044236 50 39 1,000 7,254E-04 0,014383 ! response to calcium ion GO:0051592 58 40 1,000 7,631E-04 0,01500145 ! positive regulation of response to external stimulus GO:0032103 65 40 1,000 7,631E-04 0,01487432 ! regulation of myeloid cell differentiation GO:0045637 69 40 1,000 7,631E-04 0,01474932 ! regulation of cell shape GO:0008360 78 42 1,000 8,413E-04 0,01612564 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 1,000 8,818E-04 0,01676226 ! regulation of gene-specific transcription GO:0032583 69 43 1,000 8,818E-04 0,01662487 ! vascular process in circulatory system GO:0003018 69 45 1,000 9,656E-04 0,01805639 ! response to UV GO:0009411 75 46 1,000 1,009E-03 0,01871349 ! heart morphogenesis GO:0003007 65 48 1,000 1,098E-03 0,02020718 ! regulation of DNA replication GO:0006275 75 48 1,000 1,098E-03 0,02004681 ! positive regulation of cytokine production GO:0001819 73 48 1,000 1,098E-03 0,01988896 ! regulation of angiogenesis GO:0045765 94 49 1,000 1,144E-03 0,02056077 ! cartilage development GO:0051216 70 49 1,000 1,144E-03 0,02040138 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 1,000 1,239E-03 0,02192197 ! positive regulation of organelle organization GO:0010638 82 51 1,000 1,239E-03 0,02175462 ! nucleotide-excision repair GO:0006289 64 52 1,000 1,288E-03 0,02243973 ! establishment of organelle localization GO:0051656 85 52 1,000 1,288E-03 0,02227101 ! regulation of bone remodeling GO:0046850 90 53 1,000 1,338E-03 0,02295767 ! regulation of mitosis GO:0007088 84 54 1,000 1,388E-03 0,02364964 GO:0051783|regulation of nuclear division, ! regulation of tissue remodeling GO:0034103 91 54 1,000 1,388E-03 0,02347575 ! lung development GO:0030324 94 59 1,000 1,655E-03 0,02777954 ! meiosis GO:0007126 96 61 1,000 1,768E-03 0,02946039 GO:0051327|M phase of meiotic cell cycle, ! respiratory tube development GO:0030323 99 62 1,000 1,825E-03 0,03020499 ! meiotic cell cycle GO:0051321 97 62 1,000 1,825E-03 0,02998924 ! organelle localization GO:0051640 96 62 1,000 1,825E-03 0,02977655 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 1,000 1,944E-03 0,03148292 ! respiratory system development GO:0060541 100 64 1,000 1,944E-03 0,03126276 ! adaptive immune response GO:0002250 94 64 1,000 1,944E-03 0,03104566 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! response to metal ion GO:0010038 103 70 1,000 2,32E-03 0,03679891 ! positive regulation of phosphorylation GO:0042327 102 70 1,000 2,32E-03 0,03654686 ! regulation of catabolic process GO:0009894 106 70 1,000 2,32E-03 0,03629824 ! steroid biosynthetic process GO:0006694 94 71 1,000 2,386E-03 0,03707541 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 1,000 2,452E-03 0,03785571 GO:0045937|positive regulation of phosphate metabolic process, ! negative regulation of organelle organization GO:0010639 115 72 1,000 2,452E-03 0,03760334 ! response to inorganic substance GO:0010035 115 75 1,000 2,658E-03 0,04048084 ! negative regulation of growth GO:0045926 123 75 1,000 2,658E-03 0,04021452 ! response to unfolded protein GO:0006986 99 76 1,000 2,728E-03 0,04100648 ! regulation of cell morphogenesis GO:0022604 140 76 1,000 2,728E-03 0,0407402 ! cholesterol metabolic process GO:0008203 109 77 1,000 2,799E-03 0,04153146 ! positive regulation of protein modification process GO:0031401 107 78 1,000 2,871E-03 0,04232539 ! regulation of cell cycle process GO:0010564 122 81 1,000 3,092E-03 0,04529209 ! response to protein stimulus GO:0051789 111 81 1,000 3,092E-03 0,04500543 ! microtubule cytoskeleton organization GO:0000226 120 84 1,000 3,32E-03 0,04803017 ! sterol metabolic process GO:0016125 120 84 1,000 3,32E-03 0,04772998 ! regulation of DNA metabolic process GO:0051052 135 85 1,000 3,398E-03 0,04854694 ! negative regulation of multicellular organismal process GO:0051241 133 85 1,000 3,398E-03 0,04824727 ! interphase of mitotic cell cycle GO:0051329 156 86 1,000 3,477E-03 0,0490631 ! anatomical structure homeostasis GO:0060249 136 88 1,000 3,637E-03 0,05100992 ! interphase GO:0051325 159 88 1,000 3,637E-03 0,05070077 ! response to oxidative stress GO:0006979 141 94 1,000 4,138E-03 0,05733417 ! angiogenesis GO:0001525 149 95 1,000 4,224E-03 0,05818105 ! regulation of response to external stimulus GO:0032101 139 96 1,000 4,312E-03 0,05902933 ! response to light stimulus GO:0009416 153 96 1,000 4,312E-03 0,05868004 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 5,138E-03 0,06951613 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 5,138E-03 0,0691096 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 5,138E-03 0,0687078 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 5,138E-03 0,06831065 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 5,138E-03 0,06791806 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 5,138E-03 0,06752995 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 5,138E-03 0,06714626 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 5,138E-03 0,0667669 ! sleep GO:0030431 11 5 0,000 5,138E-03 0,06639181 ! nucleotide-sugar transport GO:0015780 8 5 0,000 5,138E-03 0,0660209 ! regulation of interferon-beta production GO:0032648 5 5 0,000 5,138E-03 0,06565412 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 5,138E-03 0,06529139 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 5,138E-03 0,06493265 ! tongue development GO:0043586 6 5 0,000 5,138E-03 0,06457782 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 5,138E-03 0,06422686 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 5,138E-03 0,06387968 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 5,138E-03 0,06353625 ! cobalt ion transport GO:0006824 9 5 0,000 5,138E-03 0,06319648 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 5,138E-03 0,06286033 ! SMAD protein complex assembly GO:0007183 9 5 0,000 5,138E-03 0,06252773 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 5,138E-03 0,06219864 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 5,138E-03 0,06187299 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 5,138E-03 0,06155074 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 5,138E-03 0,06123182 ! embryonic camera-type eye development GO:0031076 8 5 0,000 5,138E-03 0,06091619 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 5,138E-03 0,0606038 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 5,138E-03 0,0602946 ! adaptation of signaling pathway GO:0022401 7 5 0,000 5,138E-03 0,05998854 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 5,138E-03 0,05968556 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 5,138E-03 0,05938564 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 5,138E-03 0,05908871 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 5,138E-03 0,05879473 ! positive regulation of histone modification GO:0031058 5 5 0,000 5,138E-03 0,05850367 ! malate metabolic process GO:0006108 7 5 0,000 5,138E-03 0,05821548 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 5,138E-03 0,05793011 ! behavioral response to pain GO:0048266 7 5 0,000 5,138E-03 0,05764752 ! clathrin coat assembly GO:0048268 11 5 0,000 5,138E-03 0,05736768 ! phototransduction, visible light GO:0007603 6 5 0,000 5,138E-03 0,05709054 ! regulation of dopamine uptake GO:0051584 9 5 0,000 5,138E-03 0,05681607 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 5,138E-03 0,05654422 ! mating behavior GO:0007617 6 5 0,000 5,138E-03 0,05627496 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 5,138E-03 0,05600825 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 5,138E-03 0,05574406 ! rhythmic behavior GO:0007622 12 5 0,000 5,138E-03 0,05548236 ! copulation GO:0007620 7 5 0,000 5,138E-03 0,05522309 ! glial cell fate commitment GO:0021781 12 5 0,000 5,138E-03 0,05496624 ! protein maturation by protein folding GO:0022417 12 5 0,000 5,138E-03 0,05471177 ! regulation of potassium ion transport GO:0043266 9 5 0,000 5,138E-03 0,05445964 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 5,138E-03 0,05420982 ! apoptotic cell clearance GO:0043277 13 5 0,000 5,138E-03 0,05396229 ! lipoprotein particle clearance GO:0034381 9 5 0,000 5,138E-03 0,05371701 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 5,138E-03 0,05347394 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 5,138E-03 0,05323307 ! response to protozoan GO:0001562 9 5 0,000 5,138E-03 0,05299436 ! lymph vessel development GO:0001945 7 5 0,000 5,138E-03 0,05275778 ! endochondral ossification GO:0001958 12 5 0,000 5,138E-03 0,0525233 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 5,138E-03 0,05229089 ! parathyroid gland development GO:0060017 8 5 0,000 5,138E-03 0,05206054 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 5,138E-03 0,0518322 ! anagen GO:0042640 6 5 0,000 5,138E-03 0,05160586 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 5,138E-03 0,05138149 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 5,138E-03 0,05115905 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 5,138E-03 0,05093854 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 5,138E-03 0,05071992 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 5,138E-03 0,05050317 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 5,138E-03 0,05028826 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 5,138E-03 0,05007518 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 5,138E-03 0,04986389 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 5,138E-03 0,04965438 ! cardiac muscle fiber development GO:0048739 7 5 0,000 5,138E-03 0,04944662 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 5,138E-03 0,04924059 ! neutrophil mediated immunity GO:0002446 6 5 0,000 5,138E-03 0,04903627 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 5,138E-03 0,04883364 ! ovulation GO:0030728 6 5 0,000 5,138E-03 0,04863268 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 5,138E-03 0,04843337 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 5,138E-03 0,04823568 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 5,138E-03 0,0480396 ! response to pH GO:0009268 9 5 0,000 5,138E-03 0,04784511 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 5,138E-03 0,04765218 ! proline biosynthetic process GO:0006561 6 5 0,000 5,138E-03 0,04746081 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 5,138E-03 0,04727097 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 5,138E-03 0,04708264 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 5,138E-03 0,0468958 ! polyol catabolic process GO:0046174 7 5 0,000 5,138E-03 0,04671044 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 5,138E-03 0,04652654 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 5,138E-03 0,04634408 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 5,138E-03 0,04616305 ! sister chromatid cohesion GO:0007062 9 5 0,000 5,138E-03 0,04598343 ! nerve growth factor processing GO:0032455 7 5 0,000 5,138E-03 0,0458052 ! urea metabolic process GO:0019627 6 5 0,000 5,138E-03 0,04562835 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 5,138E-03 0,04545285 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 5,138E-03 0,0452787 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 5,138E-03 0,04510588 ! neutrophil activation GO:0042119 5 5 0,000 5,138E-03 0,04493438 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 5,138E-03 0,04476417 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 5,138E-03 0,04459525 ! response to food GO:0032094 5 5 0,000 5,138E-03 0,0444276 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 5,138E-03 0,0442612 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 5,138E-03 0,04409605 ! paraxial mesoderm development GO:0048339 9 5 0,000 5,138E-03 0,04393213 ! forebrain neuron development GO:0021884 7 5 0,000 5,138E-03 0,04376941 ! melanosome organization GO:0032438 7 5 0,000 5,138E-03 0,0436079 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 5,138E-03 0,04344758 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 5,138E-03 0,04328843 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 5,138E-03 0,04313044 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 5,138E-03 0,04297361 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 5,138E-03 0,0428179 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 5,138E-03 0,04266333 ! nucleoside transport GO:0015858 6 5 0,000 5,138E-03 0,04250986 ! nucleoside salvage GO:0043174 7 5 0,000 5,138E-03 0,0423575 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 5,138E-03 0,04220622 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 5,138E-03 0,04205602 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 5,138E-03 0,04190689 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 5,138E-03 0,0417588 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 5,138E-03 0,04161177 ! early endosome to late endosome transport GO:0045022 11 5 0,000 5,138E-03 0,04146576 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 5,138E-03 0,04132078 ! depyrimidination GO:0045008 8 5 0,000 5,138E-03 0,0411768 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 5,138E-03 0,04103383 ! 5S class rRNA transcription GO:0042791 8 5 0,000 5,138E-03 0,04089184 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 5,138E-03 0,04075083 ! regulation of centrosome cycle GO:0046605 7 5 0,000 5,138E-03 0,0406108 ! neuronal ion channel clustering GO:0045161 7 5 0,000 5,138E-03 0,04047172 ! sodium ion homeostasis GO:0055078 6 5 0,000 5,138E-03 0,04033359 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 5,138E-03 0,0401964 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 5,138E-03 0,04006014 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 5,138E-03 0,0399248 ! monocyte differentiation GO:0030224 8 5 0,000 5,138E-03 0,03979038 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 5,138E-03 0,03965685 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 5,138E-03 0,03952422 ! centrosome duplication GO:0051298 5 5 0,000 5,138E-03 0,03939247 ! response to UV-C GO:0010225 6 5 0,000 5,138E-03 0,0392616 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 5,138E-03 0,03913159 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 5,138E-03 0,03900245 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 5,138E-03 0,03887415 ! regulation of dendrite development GO:0050773 12 5 0,000 5,138E-03 0,03874669 ! peptidyl-arginine modification GO:0018195 7 5 0,000 5,138E-03 0,03862007 ! positive regulation of organ growth GO:0046622 6 5 0,000 5,138E-03 0,03849427 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 5,138E-03 0,03836929 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 5,138E-03 0,03824512 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 5,138E-03 0,03812175 ! regulation of dopamine secretion GO:0014059 12 5 0,000 5,138E-03 0,03799917 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 5,138E-03 0,03787738 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 5,138E-03 0,03775636 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 5,138E-03 0,03763612 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 5,138E-03 0,03751664 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 5,138E-03 0,03739792 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 5,138E-03 0,03727994 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 5,138E-03 0,03716271 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 5,138E-03 0,03704621 ! neural tube patterning GO:0021532 6 5 0,000 5,138E-03 0,03693044 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 5,138E-03 0,03681539 ! histone demethylation GO:0016577 9 5 0,000 5,138E-03 0,03670106 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 5,138E-03 0,03658744 ! regulation of sterol transport GO:0032371 7 5 0,000 5,138E-03 0,03647451 GO:0032374|regulation of cholesterol transport, ! enteric nervous system development GO:0048484 8 5 0,000 5,138E-03 0,03636228 ! establishment of planar polarity GO:0001736 6 5 0,000 5,138E-03 0,03625074 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 5,138E-03 0,03613988 ! muscle cell proliferation GO:0033002 8 5 0,000 5,138E-03 0,0360297 ! transcription termination GO:0006353 8 5 0,000 5,138E-03 0,03592019 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 5,138E-03 0,03581134 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 5,138E-03 0,03570315 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 5,138E-03 0,03559561 ! regulation of respiratory burst GO:0060263 8 5 0,000 5,138E-03 0,03548871 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 5,138E-03 0,03538246 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 5,138E-03 0,03527684 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 5,138E-03 0,03517185 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 5,138E-03 0,03506748 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 5,138E-03 0,03496373 ! apical protein localization GO:0045176 6 5 0,000 5,138E-03 0,03486059 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 5,138E-03 0,03475806 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 5,138E-03 0,03465613 ! galactolipid metabolic process GO:0019374 7 5 0,000 5,138E-03 0,0345548 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 5,138E-03 0,03445406 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 5,138E-03 0,0343539 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 5,138E-03 0,03425432 ! triglyceride catabolic process GO:0019433 6 5 0,000 5,138E-03 0,03415532 ! glial cell migration GO:0008347 10 5 0,000 5,138E-03 0,03405689 ! determination of adult lifespan GO:0008340 8 5 0,000 5,138E-03 0,03395903 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 5,138E-03 0,03386172 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 5,138E-03 0,03376498 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 5,138E-03 0,03366878 ! somatic stem cell maintenance GO:0035019 13 5 0,000 5,138E-03 0,03357313 ! cerebellar cortex formation GO:0021697 6 5 0,000 5,138E-03 0,03347802 ! neural plate development GO:0001840 6 5 0,000 5,138E-03 0,03338345 ! regulation of sensory perception GO:0051931 6 5 0,000 5,138E-03 0,03328941 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 5,138E-03 0,0331959 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 5,138E-03 0,03310292 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 5,138E-03 0,03301045 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 5,138E-03 0,0329185 ! sensory cilium assembly GO:0035058 6 5 0,000 5,138E-03 0,03282706 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 5,138E-03 0,03273613 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 5,138E-03 0,0326457 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 5,138E-03 0,03255576 ! spindle assembly GO:0051225 5 5 0,000 5,138E-03 0,03246632 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 5,138E-03 0,03237737 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 5,138E-03 0,03228891 ! protein amino acid prenylation GO:0018346 9 5 0,000 5,138E-03 0,03220093 ! organ regeneration GO:0031100 7 5 0,000 5,138E-03 0,03211343 ! NAD biosynthetic process GO:0009435 7 5 0,000 5,138E-03 0,0320264 ! carnitine metabolic process GO:0009437 5 5 0,000 5,138E-03 0,03193984 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 5,138E-03 0,03185375 ! cellular anion homeostasis GO:0030002 6 5 0,000 5,138E-03 0,03176812 GO:0055081|anion homeostasis, ! tRNA transcription GO:0009304 11 6 0,000 6,163E-03 0,03800107 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 6,163E-03 0,03789946 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 6,163E-03 0,03779839 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 6,163E-03 0,03769787 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 6,163E-03 0,03759787 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 6,163E-03 0,03749841 ! regulation of helicase activity GO:0051095 11 6 0,000 6,163E-03 0,03739947 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 6,163E-03 0,03730105 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 6,163E-03 0,03720314 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 6,163E-03 0,03710575 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 6,163E-03 0,03700887 ! positive regulation of axon extension GO:0045773 8 6 0,000 6,163E-03 0,03691249 ! prostate gland development GO:0030850 9 6 0,000 6,163E-03 0,03681662 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 6,163E-03 0,03672124 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 6,163E-03 0,03662635 ! forebrain neuron differentiation GO:0021879 9 6 0,000 6,163E-03 0,03653195 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 6,163E-03 0,03643804 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 6,163E-03 0,03634461 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 6,163E-03 0,03625166 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 6,163E-03 0,03615918 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 6,163E-03 0,03606717 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 6,163E-03 0,03597563 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 6,163E-03 0,03588455 ! neuron adhesion GO:0007158 9 6 0,000 6,163E-03 0,03579393 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 6,163E-03 0,03570377 ! establishment of tissue polarity GO:0007164 7 6 0,000 6,163E-03 0,03561407 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 6,163E-03 0,03552481 ! signal peptide processing GO:0006465 8 6 0,000 6,163E-03 0,03543599 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 6,163E-03 0,03534763 ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 6,163E-03 0,0352597 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 6,163E-03 0,0351722 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 6,163E-03 0,03508514 ! opsonization GO:0008228 8 6 0,000 6,163E-03 0,03499851 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 6,163E-03 0,03491231 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 6,163E-03 0,03482653 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 6,163E-03 0,03474117 ! protein amino acid dealkylation GO:0008214 11 6 0,000 6,163E-03 0,03465623 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 6,163E-03 0,0345717 ! photoreceptor cell development GO:0042461 10 6 0,000 6,163E-03 0,03448759 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 6,163E-03 0,03440388 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 6,163E-03 0,03432058 ! mechanosensory behavior GO:0007638 8 6 0,000 6,163E-03 0,03423768 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 6,163E-03 0,03415518 ! negative regulation of endocytosis GO:0045806 8 6 0,000 6,163E-03 0,03407307 ! response to interferon-gamma GO:0034341 12 6 0,000 6,163E-03 0,03399136 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 6,163E-03 0,03391004 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 6,163E-03 0,03382911 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 6,163E-03 0,03374857 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 6,163E-03 0,0336684 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 6,163E-03 0,03358862 ! cGMP-mediated signaling GO:0019934 10 6 0,000 6,163E-03 0,03350921 ! activation of MAPKKK activity GO:0000185 10 6 0,000 6,163E-03 0,03343018 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 6,163E-03 0,03335152 ! thymic T cell selection GO:0045061 12 6 0,000 6,163E-03 0,03327323 ! protein lipoylation GO:0009249 10 6 0,000 6,163E-03 0,03319531 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 6,163E-03 0,03311775 ! pigment granule organization GO:0048753 11 6 0,000 6,163E-03 0,03304055 ! drug transport GO:0015893 6 6 0,000 6,163E-03 0,03296372 ! cysteine metabolic process GO:0006534 7 6 0,000 6,163E-03 0,03288723 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 6,163E-03 0,03281111 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 6,163E-03 0,03273533 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 6,163E-03 0,0326599 ! histidine metabolic process GO:0006547 6 6 0,000 6,163E-03 0,03258482 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 6,163E-03 0,03251009 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 6,163E-03 0,03243569 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 6,163E-03 0,03236164 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 6,163E-03 0,03228792 ! adenohypophysis development GO:0021984 10 6 0,000 6,163E-03 0,03221454 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 6,163E-03 0,03214149 ! hyperosmotic response GO:0006972 8 6 0,000 6,163E-03 0,03206877 ! microtubule nucleation GO:0007020 10 6 0,000 6,163E-03 0,03199638 ! ER overload response GO:0006983 7 6 0,000 6,163E-03 0,03192432 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 6,163E-03 0,03185258 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 6,163E-03 0,03178116 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 6,163E-03 0,03171006 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 6,163E-03 0,03163928 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 6,163E-03 0,03156881 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 6,163E-03 0,03149866 ! response to dietary excess GO:0002021 7 6 0,000 6,163E-03 0,03142882 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 6,163E-03 0,03135929 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 6,163E-03 0,03129006 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 6,163E-03 0,03122114 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 6,163E-03 0,03115252 ! glycerol ether catabolic process GO:0044269 8 6 0,000 6,163E-03 0,03108421 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 6,163E-03 0,03101619 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 6,163E-03 0,03094847 ! neuron apoptosis GO:0051402 8 6 0,000 6,163E-03 0,03088104 ! organic alcohol transport GO:0015850 9 6 0,000 6,163E-03 0,03081391 ! T cell mediated immunity GO:0002456 12 6 0,000 6,163E-03 0,03074707 ! male sex determination GO:0030238 9 6 0,000 6,163E-03 0,03068051 ! carnitine transport GO:0015879 8 6 0,000 6,163E-03 0,03061425 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 6,163E-03 0,03054827 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 6,163E-03 0,03048258 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 6,163E-03 0,03041716 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 6,163E-03 0,03035203 ! positive regulation of exocytosis GO:0045921 6 6 0,000 6,163E-03 0,03028717 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 6,163E-03 0,0302226 ! parturition GO:0007567 12 6 0,000 6,163E-03 0,03015829 ! negative regulation of translational initiation GO:0045947 7 6 0,000 6,163E-03 0,03009426 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 6,163E-03 0,0300305 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 6,163E-03 0,02996701 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 6,163E-03 0,02990379 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 6,163E-03 0,02984084 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 6,163E-03 0,02977815 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 6,163E-03 0,02971572 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 6,163E-03 0,02965355 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 6,163E-03 0,02959164 ! macrophage differentiation GO:0030225 10 6 0,000 6,163E-03 0,02953 ! astrocyte development GO:0014002 14 6 0,000 6,163E-03 0,0294686 ! hyaluronan metabolic process GO:0030212 6 6 0,000 6,163E-03 0,02940746 ! purine base biosynthetic process GO:0009113 14 6 0,000 6,163E-03 0,02934658 ! interaction with symbiont GO:0051702 8 6 0,000 6,163E-03 0,02928595 ! anterograde axon cargo transport GO:0008089 8 6 0,000 6,163E-03 0,02922556 ! skeletal muscle contraction GO:0003009 6 6 0,000 6,163E-03 0,02916543 ! eating behavior GO:0042755 6 6 0,000 6,163E-03 0,02910554 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 6,163E-03 0,0290459 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 6,163E-03 0,0289865 ! response to copper ion GO:0046688 9 6 0,000 6,163E-03 0,02892734 ! response to exogenous dsRNA GO:0043330 8 6 0,000 6,163E-03 0,02886843 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 6,163E-03 0,02880975 ! establishment of melanosome localization GO:0032401 9 6 0,000 6,163E-03 0,02875131 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 6,163E-03 0,02869311 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 6,163E-03 0,02863515 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 6,163E-03 0,02857742 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 6,163E-03 0,02851992 ! nucleoside catabolic process GO:0009164 6 6 0,000 6,163E-03 0,02846265 ! hair follicle maturation GO:0048820 7 6 0,000 6,163E-03 0,02840561 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 6,163E-03 0,0283488 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 6,163E-03 0,02829221 ! Schwann cell development GO:0014044 14 6 0,000 6,163E-03 0,02823585 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 6,163E-03 0,02817972 ! dendrite morphogenesis GO:0048813 9 6 0,000 6,163E-03 0,02812381 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 6,163E-03 0,02806811 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 6,163E-03 0,02801264 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 6,163E-03 0,02795739 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 6,163E-03 0,02790236 ! histone ubiquitination GO:0016574 7 6 0,000 6,163E-03 0,02784754 ! regulation of meiosis GO:0040020 10 6 0,000 6,163E-03 0,02779294 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 6,163E-03 0,02773855 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 6,163E-03 0,02768437 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 6,163E-03 0,02763041 ! regulation of mast cell activation GO:0033003 6 6 0,000 6,163E-03 0,02757665 ! membrane to membrane docking GO:0022614 12 6 0,000 6,163E-03 0,0275231 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 6,163E-03 0,02746976 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 6,163E-03 0,02741663 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 6,163E-03 0,0273637 ! receptor internalization GO:0031623 9 6 0,000 6,163E-03 0,02731098 ! neutrophil homeostasis GO:0001780 6 6 0,000 6,163E-03 0,02725846 ! coenzyme A metabolic process GO:0015936 9 6 0,000 6,163E-03 0,02720614 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 6,163E-03 0,02715402 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 6,163E-03 0,0271021 ! protein deubiquitination GO:0016579 8 6 0,000 6,163E-03 0,02705038 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 6,163E-03 0,02699885 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 6,163E-03 0,02694752 ! peptidyl-histidine modification GO:0018202 9 6 0,000 6,163E-03 0,02689639 ! axonal fasciculation GO:0007413 9 6 0,000 6,163E-03 0,02684545 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 6,163E-03 0,0267947 ! thiamin metabolic process GO:0006772 6 6 0,000 6,163E-03 0,02674415 ! midbrain development GO:0030901 6 6 0,000 6,163E-03 0,02669378 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 6,163E-03 0,02664361 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 6,163E-03 0,02659362 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 6,163E-03 0,02654382 ! progesterone metabolic process GO:0042448 8 6 0,000 6,163E-03 0,0264942 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 6,163E-03 0,02644477 ! glycolipid catabolic process GO:0019377 13 6 0,000 6,163E-03 0,02639553 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 6,163E-03 0,02634646 ! positive regulation of glucose import GO:0046326 6 6 0,000 6,163E-03 0,02629758 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 6,163E-03 0,02624888 ! adult feeding behavior GO:0008343 6 6 0,000 6,163E-03 0,02620037 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 6,163E-03 0,02615203 ! blastocyst growth GO:0001832 15 6 0,000 6,163E-03 0,02610386 ! pigment granule transport GO:0051904 12 6 0,000 6,163E-03 0,02605588 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 6,163E-03 0,02600807 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 6,163E-03 0,02596044 ! catecholamine transport GO:0051937 7 6 0,000 6,163E-03 0,02591298 ! organ or tissue specific immune response GO:0002251 7 6 0,000 6,163E-03 0,02586569 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 6,163E-03 0,02581858 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 6,163E-03 0,02577163 ! negative regulation of B cell activation GO:0050869 9 6 0,000 6,163E-03 0,02572486 ! protein prenylation GO:0018342 10 6 0,000 6,163E-03 0,02567826 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 6,163E-03 0,02563182 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 6,163E-03 0,02558556 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 6,163E-03 0,02553946 ! positive regulation of coagulation GO:0050820 11 6 0,000 6,163E-03 0,02549352 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 7,186E-03 0,02967462 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 7,186E-03 0,02962144 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 7,186E-03 0,02956845 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 7,186E-03 0,02951565 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 7,186E-03 0,02946303 ! synaptonemal complex assembly GO:0007130 10 7 0,000 7,186E-03 0,02941061 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 7,186E-03 0,02935837 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 7,186E-03 0,02930631 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 7,186E-03 0,02925445 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 7,186E-03 0,02920276 ! reproductive behavior GO:0019098 12 7 0,000 7,186E-03 0,02915126 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 7,186E-03 0,02909993 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 7,186E-03 0,02904879 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 7,186E-03 0,02899783 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 7,186E-03 0,02894704 ! oligopeptide transport GO:0006857 11 7 0,000 7,186E-03 0,02889644 ! protein amino acid sulfation GO:0006477 9 7 0,000 7,186E-03 0,02884601 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 7,186E-03 0,02879575 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 7,186E-03 0,02874567 ! RNA methylation GO:0001510 11 7 0,000 7,186E-03 0,02869577 ! pericardium development GO:0060039 8 7 0,000 7,186E-03 0,02864603 ! macrophage chemotaxis GO:0048246 10 7 0,000 7,186E-03 0,02859647 ! fibril organization GO:0043206 13 7 0,000 7,186E-03 0,02854708 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 7,186E-03 0,02849786 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 7,186E-03 0,02844882 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 7,186E-03 0,02839993 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 7,186E-03 0,02835122 ! lipoprotein transport GO:0042953 9 7 0,000 7,186E-03 0,02830267 ! cerebral cortex cell migration GO:0021795 11 7 0,000 7,186E-03 0,02825429 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 7,186E-03 0,02820608 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 7,186E-03 0,02815803 ! estrogen metabolic process GO:0008210 14 7 0,000 7,186E-03 0,02811014 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 7,186E-03 0,02806241 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 7,186E-03 0,02801485 ! chemosensory behavior GO:0007635 9 7 0,000 7,186E-03 0,02796745 ! microtubule bundle formation GO:0001578 8 7 0,000 7,186E-03 0,02792021 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 7,186E-03 0,02787312 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 7,186E-03 0,0278262 ! leukocyte degranulation GO:0043299 10 7 0,000 7,186E-03 0,02777943 ! bile acid and bile salt transport GO:0015721 9 7 0,000 7,186E-03 0,02773282 ! reflex GO:0060004 12 7 0,000 7,186E-03 0,02768637 ! positive regulation of isotype switching GO:0045830 15 7 0,000 7,186E-03 0,02764007 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 7,186E-03 0,02759393 ! protein-cofactor linkage GO:0018065 13 7 0,000 7,186E-03 0,02754794 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 7,186E-03 0,0275021 ! glycerolipid catabolic process GO:0046503 9 7 0,000 7,186E-03 0,02745641 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 7,186E-03 0,02741088 ! spinal cord patterning GO:0021511 7 7 0,000 7,186E-03 0,0273655 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 7,186E-03 0,02732027 ! adrenal gland development GO:0030325 17 7 0,000 7,186E-03 0,02727518 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 7,186E-03 0,02723025 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 7,186E-03 0,02718546 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 7,186E-03 0,02714082 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 7,186E-03 0,02709633 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 7,186E-03 0,02705198 ! endosome organization GO:0007032 10 7 0,000 7,186E-03 0,02700778 ! thyroid hormone generation GO:0006590 11 7 0,000 7,186E-03 0,02696372 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 7,186E-03 0,02691981 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 7,186E-03 0,02687604 ! regulation of pigmentation during development GO:0048070 15 7 0,000 7,186E-03 0,02683241 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 7,186E-03 0,02678892 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 7,186E-03 0,02674557 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 7,186E-03 0,02670236 ! galactose metabolic process GO:0006012 10 7 0,000 7,186E-03 0,02665929 ! vesicle fusion GO:0006906 15 7 0,000 7,186E-03 0,02661636 ! intracellular pH reduction GO:0051452 10 7 0,000 7,186E-03 0,02657357 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 7,186E-03 0,02653092 ! organ growth GO:0035265 11 7 0,000 7,186E-03 0,0264884 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 7,186E-03 0,02644602 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 7,186E-03 0,02640377 ! Rac protein signal transduction GO:0016601 7 7 0,000 7,186E-03 0,02636166 ! retinol metabolic process GO:0042572 9 7 0,000 7,186E-03 0,02631968 ! behavioral fear response GO:0001662 13 7 0,000 7,186E-03 0,02627784 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 7,186E-03 0,02623613 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 7,186E-03 0,02619455 ! rRNA modification GO:0000154 12 7 0,000 7,186E-03 0,0261531 ! protein heterooligomerization GO:0051291 10 7 0,000 7,186E-03 0,02611179 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 7,186E-03 0,0260706 ! response to UV-B GO:0010224 11 7 0,000 7,186E-03 0,02602955 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 7,186E-03 0,02598862 ! protein retention in ER lumen GO:0006621 12 7 0,000 7,186E-03 0,02594782 ! intermediate filament organization GO:0045109 11 7 0,000 7,186E-03 0,02590715 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 7,186E-03 0,02586661 ! cardiac muscle cell development GO:0055013 9 7 0,000 7,186E-03 0,02582619 ! fibrinolysis GO:0042730 9 7 0,000 7,186E-03 0,0257859 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 7,186E-03 0,02574573 ! regulation of circadian rhythm GO:0042752 11 7 0,000 7,186E-03 0,02570569 ! B cell lineage commitment GO:0002326 17 7 0,000 7,186E-03 0,02566578 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 7,186E-03 0,02562599 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 7,186E-03 0,02558632 ! response to tropane GO:0014073 13 7 0,000 7,186E-03 0,02554677 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 7,186E-03 0,02550735 ! melanosome localization GO:0032400 10 7 0,000 7,186E-03 0,02546805 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 7,186E-03 0,02542886 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 7,186E-03 0,0253898 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 7,186E-03 0,02535086 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 7,186E-03 0,02531204 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 7,186E-03 0,02527334 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 7,186E-03 0,02523475 ! mast cell activation GO:0045576 9 7 0,000 7,186E-03 0,02519628 ! multicellular organismal aging GO:0010259 11 7 0,000 7,186E-03 0,02515793 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 7,186E-03 0,0251197 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 7,186E-03 0,02508158 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 7,186E-03 0,02504358 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 7,186E-03 0,02500569 ! establishment of nucleus localization GO:0040023 13 7 0,000 7,186E-03 0,02496792 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 7,186E-03 0,02493026 ! T cell lineage commitment GO:0002360 12 7 0,000 7,186E-03 0,02489271 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 7,186E-03 0,02485528 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 7,186E-03 0,02481796 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 7,186E-03 0,02478075 ! regulation of lipid transport GO:0032368 13 7 0,000 7,186E-03 0,02474366 ! response to tumor cell GO:0002347 12 7 0,000 7,186E-03 0,02470667 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 7,186E-03 0,02466979 ! neuroblast proliferation GO:0007405 13 7 0,000 7,186E-03 0,02463303 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 7,186E-03 0,02459637 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 7,186E-03 0,02455982 ! peptidyl-threonine modification GO:0018210 18 7 0,000 7,186E-03 0,02452339 ! diuresis GO:0030146 12 7 0,000 7,186E-03 0,02448705 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 7,186E-03 0,02445083 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 7,186E-03 0,02441471 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 7,186E-03 0,0243787 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 7,186E-03 0,0243428 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 7,186E-03 0,024307 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 7,186E-03 0,02427131 ! melanin biosynthetic process GO:0042438 8 7 0,000 7,186E-03 0,02423572 ! regulation of synaptogenesis GO:0051963 10 7 0,000 7,186E-03 0,02420024 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 7,186E-03 0,02416486 ! dopamine biosynthetic process GO:0042416 15 7 0,000 7,186E-03 0,02412958 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 7,186E-03 0,0240944 ! lymph node development GO:0048535 9 7 0,000 7,186E-03 0,02405933 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 7,186E-03 0,02402436 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 7,186E-03 0,02398949 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 7,186E-03 0,02395473 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 7,186E-03 0,02392006 ! endosome to lysosome transport GO:0008333 10 7 0,000 7,186E-03 0,02388549 ! ATP catabolic process GO:0006200 10 7 0,000 7,186E-03 0,02385103 ! establishment of pigment granule localization GO:0051905 13 7 0,000 7,186E-03 0,02381666 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 7,186E-03 0,02378239 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 7,186E-03 0,02374822 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 7,186E-03 0,02371415 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 7,186E-03 0,02368017 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 7,186E-03 0,0236463 ! muscle adaptation GO:0043500 12 7 0,000 7,186E-03 0,02361252 ! amino sugar catabolic process GO:0046348 9 7 0,000 7,186E-03 0,02357883 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 7,186E-03 0,02354524 ! retina homeostasis GO:0001895 9 7 0,000 7,186E-03 0,02351175 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 7,186E-03 0,02347835 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 7,186E-03 0,02344505 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 7,186E-03 0,02341184 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 7,186E-03 0,02337873 ! behavioral response to nicotine GO:0035095 11 7 0,000 7,186E-03 0,02334571 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 7,186E-03 0,02331278 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 7,186E-03 0,02327995 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 8,209E-03 0,02655532 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 8,209E-03 0,02651803 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 8,209E-03 0,02648083 ! axon extension GO:0048675 11 8 0,000 8,209E-03 0,02644375 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 8,209E-03 0,02640676 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 8,209E-03 0,02636988 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 8,209E-03 0,0263331 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 8,209E-03 0,02629643 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 8,209E-03 0,02625985 ! cell proliferation in forebrain GO:0021846 10 8 0,000 8,209E-03 0,02622338 ! positive regulation of B cell proliferation GO:0030890 11 8 0,000 8,209E-03 0,02618701 ! phosphate transport GO:0006817 10 8 0,000 8,209E-03 0,02615074 ! N-glycan processing GO:0006491 12 8 0,000 8,209E-03 0,02611457 ! Golgi to endosome transport GO:0006895 16 8 0,000 8,209E-03 0,0260785 ! UTP metabolic process GO:0046051 8 8 0,000 8,209E-03 0,02604253 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 8,209E-03 0,02600666 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 8,209E-03 0,02597089 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 10 8 0,000 8,209E-03 0,02593521 ! succinate metabolic process GO:0006105 14 8 0,000 8,209E-03 0,02589964 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 8,209E-03 0,02586416 ! smoothened signaling pathway GO:0007224 8 8 0,000 8,209E-03 0,02582878 ! membrane hyperpolarization GO:0060081 10 8 0,000 8,209E-03 0,02579349 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 8,209E-03 0,0257583 ! keratinocyte proliferation GO:0043616 12 8 0,000 8,209E-03 0,02572321 ! middle ear morphogenesis GO:0042474 9 8 0,000 8,209E-03 0,02568821 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 8,209E-03 0,02565331 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 8,209E-03 0,0256185 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 8,209E-03 0,02558379 ! ganglioside metabolic process GO:0001573 15 8 0,000 8,209E-03 0,02554917 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 8,209E-03 0,02551464 ! pseudouridine synthesis GO:0001522 9 8 0,000 8,209E-03 0,02548021 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 8,209E-03 0,02544587 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 8,209E-03 0,02541162 ! endothelial cell differentiation GO:0045446 14 8 0,000 8,209E-03 0,02537747 ! ceramide biosynthetic process GO:0046513 9 8 0,000 8,209E-03 0,0253434 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 8,209E-03 0,02530943 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 0,000 8,209E-03 0,02527555 ! astrocyte differentiation GO:0048708 16 8 0,000 8,209E-03 0,02524176 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 8,209E-03 0,02520806 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 8,209E-03 0,02517445 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 8,209E-03 0,02514093 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 8,209E-03 0,02510749 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 8,209E-03 0,02507415 ! melanin metabolic process GO:0006582 12 8 0,000 8,209E-03 0,0250409 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 8,209E-03 0,02500773 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 8,209E-03 0,02497465 ! macrophage activation GO:0042116 12 8 0,000 8,209E-03 0,02494166 ! regulation of type I interferon production GO:0032479 8 8 0,000 8,209E-03 0,02490875 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 8,209E-03 0,02487594 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 8,209E-03 0,0248432 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 8,209E-03 0,02481056 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 8,209E-03 0,024778 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 8,209E-03 0,02474552 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 8,209E-03 0,02471313 ! ruffle organization GO:0031529 11 8 0,000 8,209E-03 0,02468083 ! osteoblast development GO:0002076 13 8 0,000 8,209E-03 0,02464861 ! lens development in camera-type eye GO:0002088 10 8 0,000 8,209E-03 0,02461647 ! positive regulation of vasodilation GO:0045909 12 8 0,000 8,209E-03 0,02458442 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 8,209E-03 0,02455245 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 8,209E-03 0,02452056 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 8,209E-03 0,02448876 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 8,209E-03 0,02445704 ! Schwann cell differentiation GO:0014037 17 8 0,000 8,209E-03 0,0244254 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 8,209E-03 0,02439384 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 8,209E-03 0,02436237 ! regulation of gliogenesis GO:0014013 20 8 0,000 8,209E-03 0,02433097 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 8,209E-03 0,02429966 ! oligodendrocyte development GO:0014003 8 8 0,000 8,209E-03 0,02426843 ! segment specification GO:0007379 10 8 0,000 8,209E-03 0,02423727 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 8,209E-03 0,0242062 ! cellular extravasation GO:0045123 11 8 0,000 8,209E-03 0,0241752 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 8,209E-03 0,02414429 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 8,209E-03 0,02411345 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 8,209E-03 0,0240827 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 8,209E-03 0,02405202 ! snRNA metabolic process GO:0016073 10 8 0,000 8,209E-03 0,02402142 GO:0016180|snRNA processing, ! phosphoinositide 3-kinase cascade GO:0014065 23 8 0,000 8,209E-03 0,0239909 ! regulation of interleukin-4 production GO:0032673 16 8 0,000 8,209E-03 0,02396045 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 8,209E-03 0,02393008 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 8,209E-03 0,02389979 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 8,209E-03 0,02386958 ! nucleosome disassembly GO:0006337 12 8 0,000 8,209E-03 0,02383944 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 8,209E-03 0,02380938 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 8,209E-03 0,02377939 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 8,209E-03 0,02374948 ! icosanoid secretion GO:0032309 12 8 0,000 8,209E-03 0,02371964 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 8,209E-03 0,02368988 ! leukocyte activation during immune response GO:0002366 13 8 0,000 8,209E-03 0,02366019 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 8,209E-03 0,02363058 ! cerebellum morphogenesis GO:0021587 9 8 0,000 8,209E-03 0,02360104 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 8,209E-03 0,02357158 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 8,209E-03 0,02354219 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 8,209E-03 0,02351287 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 8,209E-03 0,02348363 ! sterol catabolic process GO:0016127 9 8 0,000 8,209E-03 0,02345445 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 8,209E-03 0,02342535 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 8,209E-03 0,02339633 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 8,209E-03 0,02336737 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 8,209E-03 0,02333849 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 8,209E-03 0,02330967 ! prophase GO:0051324 11 8 0,000 8,209E-03 0,02328093 ! S phase GO:0051320 8 8 0,000 8,209E-03 0,02325226 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 8,209E-03 0,02322366 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 8,209E-03 0,02319513 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 8,209E-03 0,02316667 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 8,209E-03 0,02313828 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 8,209E-03 0,02310996 ! hormone catabolic process GO:0042447 13 8 0,000 8,209E-03 0,02308171 ! quaternary ammonium group transport GO:0015697 10 8 0,000 8,209E-03 0,02305352 ! myeloid cell homeostasis GO:0002262 8 8 0,000 8,209E-03 0,02302541 ! regulation of fibrinolysis GO:0051917 13 8 0,000 8,209E-03 0,02299736 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 8,209E-03 0,02296939 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 8,209E-03 0,02294148 ! regulation of telomere maintenance GO:0032204 10 8 0,000 8,209E-03 0,02291363 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 8,209E-03 0,02288586 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 8,209E-03 0,02285815 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 8,209E-03 0,02283051 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 8,209E-03 0,02280294 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 8,209E-03 0,02277543 ! lamellipodium assembly GO:0030032 9 8 0,000 8,209E-03 0,02274799 ! regulation of embryonic development GO:0045995 16 8 0,000 8,209E-03 0,02272062 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 8,209E-03 0,02269331 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 8,209E-03 0,02266607 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 9,231E-03 0,02545638 ! regulation of developmental growth GO:0048638 13 9 0,000 9,231E-03 0,02542589 ! telencephalon cell migration GO:0022029 16 9 0,000 9,231E-03 0,02539548 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 9,231E-03 0,02536514 ! pentose-phosphate shunt GO:0006098 12 9 0,000 9,231E-03 0,02533487 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 9,231E-03 0,02530467 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 9,231E-03 0,02527455 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 9,231E-03 0,02524449 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 9,231E-03 0,02521451 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 9,231E-03 0,0251846 ! GTP metabolic process GO:0046039 9 9 0,000 9,231E-03 0,02515476 ! elastic fiber assembly GO:0048251 13 9 0,000 9,231E-03 0,02512499 ! social behavior GO:0035176 14 9 0,000 9,231E-03 0,0250953 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 9,231E-03 0,02506567 ! artery development GO:0060840 19 9 0,000 9,231E-03 0,02503611 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 9,231E-03 0,02500662 ! response to pain GO:0048265 16 9 0,000 9,231E-03 0,0249772 ! protein complex disassembly GO:0043241 17 9 0,000 9,231E-03 0,02494785 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 9,231E-03 0,02491857 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 9,231E-03 0,02488936 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 9,231E-03 0,02486021 ! ciliary or flagellar motility GO:0001539 10 9 0,000 9,231E-03 0,02483113 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 9,231E-03 0,02480213 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 9,231E-03 0,02477319 ! regulation of exit from mitosis GO:0007096 12 9 0,000 9,231E-03 0,02474431 ! ventral spinal cord development GO:0021517 11 9 0,000 9,231E-03 0,02471551 ! protein targeting to ER GO:0045047 19 9 0,000 9,231E-03 0,02468677 ! T cell selection GO:0045058 18 9 0,000 9,231E-03 0,0246581 ! endoderm development GO:0007492 12 9 0,000 9,231E-03 0,02462949 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 9,231E-03 0,02460095 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 9,231E-03 0,02457248 ! arginine catabolic process GO:0006527 10 9 0,000 9,231E-03 0,02454407 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 9,231E-03 0,02451573 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 9,231E-03 0,02448745 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 9,231E-03 0,02445924 ! phosphagen metabolic process GO:0006599 12 9 0,000 9,231E-03 0,02443109 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 9,231E-03 0,02440301 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 9,231E-03 0,02437499 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 9,231E-03 0,02434704 ! regulation of stress fiber formation GO:0051492 20 9 0,000 9,231E-03 0,02431915 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 9,231E-03 0,02429133 ! mannose metabolic process GO:0006013 9 9 0,000 9,231E-03 0,02426357 ! substrate-bound cell migration GO:0006929 10 9 0,000 9,231E-03 0,02423587 ! receptor clustering GO:0043113 15 9 0,000 9,231E-03 0,02420823 ! epithelial cell development GO:0002064 10 9 0,000 9,231E-03 0,02418066 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 9,231E-03 0,02415315 ! retinoic acid metabolic process GO:0042573 11 9 0,000 9,231E-03 0,0241257 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 9,231E-03 0,02409832 ! positive regulation of translational initiation GO:0045948 10 9 0,000 9,231E-03 0,024071 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 9,231E-03 0,02404374 ! motor axon guidance GO:0008045 14 9 0,000 9,231E-03 0,02401654 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 9,231E-03 0,0239894 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 9,231E-03 0,02396233 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 9,231E-03 0,02393531 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 9,231E-03 0,02390836 ! blastoderm segmentation GO:0007350 11 9 0,000 9,231E-03 0,02388146 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 9,231E-03 0,02385463 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 9,231E-03 0,02382786 ! response to amine stimulus GO:0014075 13 9 0,000 9,231E-03 0,02380114 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 9,231E-03 0,02377449 ! erythrocyte development GO:0048821 11 9 0,000 9,231E-03 0,0237479 ! renal water homeostasis GO:0003091 14 9 0,000 9,231E-03 0,02372136 ! postreplication repair GO:0006301 11 9 0,000 9,231E-03 0,02369489 ! mRNA cleavage GO:0006379 13 9 0,000 9,231E-03 0,02366847 ! hindbrain morphogenesis GO:0021575 12 9 0,000 9,231E-03 0,02364212 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 9,231E-03 0,02361582 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 9,231E-03 0,02358958 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 9,231E-03 0,0235634 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 9,231E-03 0,02353727 ! acid secretion GO:0046717 14 9 0,000 9,231E-03 0,02351121 ! musculoskeletal movement GO:0050881 11 9 0,000 9,231E-03 0,0234852 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 9,231E-03 0,02345925 ! methionine biosynthetic process GO:0009086 10 9 0,000 9,231E-03 0,02343336 ! purine base metabolic process GO:0006144 18 9 0,000 9,231E-03 0,02340752 ! oocyte differentiation GO:0009994 12 9 0,000 9,231E-03 0,02338174 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 9,231E-03 0,02335602 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 9,231E-03 0,02333035 ! spleen development GO:0048536 15 9 0,000 9,231E-03 0,02330474 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 9,231E-03 0,02327919 ! anterior/posterior axis specification GO:0009948 11 9 0,000 9,231E-03 0,02325369 ! regulation of RNA splicing GO:0043484 14 9 0,000 9,231E-03 0,02322825 ! detection of calcium ion GO:0005513 13 9 0,000 9,231E-03 0,02320286 ! blastocyst formation GO:0001825 12 9 0,000 9,231E-03 0,02317753 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 9,231E-03 0,02315226 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 9,231E-03 0,02312704 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 9,231E-03 0,02310187 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 9,231E-03 0,02307676 ! regulation of amino acid transport GO:0051955 11 9 0,000 9,231E-03 0,0230517 ! positive regulation of amine transport GO:0051954 15 9 0,000 9,231E-03 0,0230267 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 9,231E-03 0,02300176 ! prepulse inhibition GO:0060134 14 9 0,000 9,231E-03 0,02297686 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 9,231E-03 0,02295202 ! insulin secretion GO:0030073 17 9 0,000 9,231E-03 0,02292724 ! sequestering of metal ion GO:0051238 11 9 0,000 9,231E-03 0,0229025 ! response to nicotine GO:0035094 16 9 0,000 9,231E-03 0,02287782 ! establishment of cell polarity GO:0030010 12 9 0,000 9,231E-03 0,0228532 ! nucleus localization GO:0051647 15 9 0,000 9,231E-03 0,02282862 ! regulation of synapse organization GO:0050807 12 9 0,000 9,231E-03 0,0228041 ! localization within membrane GO:0051668 15 9 0,000 9,231E-03 0,02277964 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,01025136 0,0252713 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,01025136 0,02524424 ! neuron fate specification GO:0048665 11 10 0,000 0,01025136 0,02521724 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,01025136 0,0251903 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,01025136 0,02516341 ! thyroid gland development GO:0030878 19 10 0,000 0,01025136 0,02513659 ! regulation of B cell proliferation GO:0030888 15 10 0,000 0,01025136 0,02510982 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,01025136 0,02508311 ! synapsis GO:0007129 13 10 0,000 0,01025136 0,02505645 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,01025136 0,02502985 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,01025136 0,02500331 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,01025136 0,02497682 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,01025136 0,02495039 ! sulfate transport GO:0008272 12 10 0,000 0,01025136 0,02492402 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,01025136 0,0248977 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,01025136 0,02487143 ! androgen metabolic process GO:0008209 13 10 0,000 0,01025136 0,02484523 ! phospholipid efflux GO:0033700 16 10 0,000 0,01025136 0,02481907 ! hippocampus development GO:0021766 19 10 0,000 0,01025136 0,02479297 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,01025136 0,02476693 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,01025136 0,02474094 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,01025136 0,02471501 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,01025136 0,02468913 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,01025136 0,0246633 ! pathogenesis GO:0009405 13 10 0,000 0,01025136 0,02463753 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,01025136 0,02461182 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01025136 0,02458615 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,01025136 0,02456054 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 0,01025136 0,02453498 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,01025136 0,02450948 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,01025136 0,02448403 ! melanocyte differentiation GO:0030318 15 10 0,000 0,01025136 0,02445863 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,01025136 0,02443328 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,01025136 0,02440799 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,01025136 0,02438275 ! response to X-ray GO:0010165 16 10 0,000 0,01025136 0,02435756 ! B cell proliferation GO:0042100 14 10 0,000 0,01025136 0,02433242 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,01025136 0,02430734 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,01025136 0,02428231 ! forebrain cell migration GO:0021885 17 10 0,000 0,01025136 0,02425732 ! lipid digestion GO:0044241 15 10 0,000 0,01025136 0,02423239 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,01025136 0,02420751 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,01025136 0,02418269 ! UV protection GO:0009650 14 10 0,000 0,01025136 0,02415791 ! entry into host cell GO:0030260 20 10 0,000 0,01025136 0,02413318 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,01025136 0,02410851 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,01025136 0,02408388 ! negative regulation of ossification GO:0030279 19 10 0,000 0,01025136 0,02405931 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,01025136 0,02403478 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,01025136 0,0240103 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,01025136 0,02398588 ! regulation of organ growth GO:0046620 11 10 0,000 0,01025136 0,0239615 ! response to dsRNA GO:0043331 18 10 0,000 0,01025136 0,02393718 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,01025136 0,0239129 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,01025136 0,02388867 ! embryonic axis specification GO:0000578 12 10 0,000 0,01025136 0,02386449 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,01025136 0,02384036 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,01025136 0,02381628 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,01025136 0,02379225 ! cranial nerve development GO:0021545 12 10 0,000 0,01025136 0,02376827 ! fucose catabolic process GO:0019317 16 10 0,000 0,01025136 0,02374433 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,01025136 0,02372044 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,01025136 0,0236966 ! protein sumoylation GO:0016925 12 10 0,000 0,01025136 0,02367281 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,01025136 0,02364907 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01025136 0,02362537 ! zymogen activation GO:0031638 14 10 0,000 0,01025136 0,02360172 ! salivary gland development GO:0007431 22 10 0,000 0,01025136 0,02357812 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,01025136 0,02355456 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,01025136 0,02353106 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,01025136 0,0235076 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,01025136 0,02348418 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,01025136 0,02346081 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,01025136 0,02343749 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,01025136 0,02341422 ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,01025136 0,02339099 ! detection of bacterium GO:0016045 10 10 0,000 0,01025136 0,02336781 ! embryonic gut development GO:0048566 11 10 0,000 0,01025136 0,02334467 ! activation of innate immune response GO:0002218 10 10 0,000 0,01025136 0,02332158 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,01025136 0,02329854 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,01025136 0,02327554 ! developmental induction GO:0031128 13 10 0,000 0,01025136 0,02325258 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,01025136 0,02322967 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,01025136 0,02320681 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,01025136 0,02318399 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,01025136 0,02316122 ! rRNA transcription GO:0009303 17 11 0,000 0,01127101 0,02543997 ! respiratory burst GO:0045730 14 11 0,000 0,01127101 0,02541503 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,01127101 0,02539014 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,01127101 0,0253653 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,01127101 0,0253405 ! virus-host interaction GO:0019048 17 11 0,000 0,01127101 0,02531576 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,01127101 0,02529106 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,01127101 0,02526641 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,01127101 0,02524181 ! RNA polyadenylation GO:0043631 19 11 0,000 0,01127101 0,02521725 ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,01127101 0,02519274 ! mating GO:0007618 14 11 0,000 0,01127101 0,02516829 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,01127101 0,02514387 ! T cell proliferation GO:0042098 20 11 0,000 0,01127101 0,02511951 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,01127101 0,02509519 ! bone resorption GO:0045453 16 11 0,000 0,01127101 0,02507092 ! regulated secretory pathway GO:0045055 14 11 0,000 0,01127101 0,0250467 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,01127101 0,02502252 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,01127101 0,02499839 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,01127101 0,02497431 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,01127101 0,02495027 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,01127101 0,02492628 ! syncytium formation GO:0006949 15 11 0,000 0,01127101 0,02490234 ! plasma membrane organization GO:0007009 18 11 0,000 0,01127101 0,02487844 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,01127101 0,02485459 ! focal adhesion formation GO:0048041 24 11 0,000 0,01127101 0,02483078 ! mitotic spindle organization GO:0007052 15 11 0,000 0,01127101 0,02480702 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,01127101 0,0247833 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,01127101 0,02475963 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,01127101 0,02473601 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,01127101 0,02471243 ! adult heart development GO:0007512 11 11 0,000 0,01127101 0,02468889 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,01127101 0,0246654 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,01127101 0,02464195 ! temperature homeostasis GO:0001659 16 11 0,000 0,01127101 0,02461855 ! L-glutamate transport GO:0015813 16 11 0,000 0,01127101 0,02459519 GO:0015800|acidic amino acid transport, ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,01127101 0,02457188 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,01127101 0,02454861 ! stem cell development GO:0048864 29 11 0,000 0,01127101 0,02452539 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,01127101 0,02450221 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,01127101 0,02447907 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,01127101 0,02445598 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,01127101 0,02443293 ! vasoconstriction GO:0042310 15 11 0,000 0,01127101 0,02440992 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,01127101 0,02438696 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,01127101 0,02436404 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,01127101 0,02434116 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,01127101 0,02431832 ! ribosome assembly GO:0042255 13 11 0,000 0,01127101 0,02429553 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,01127101 0,02427278 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,01127101 0,02425008 ! chromatin silencing GO:0006342 19 11 0,000 0,01127101 0,02422741 ! nucleosome positioning GO:0016584 13 11 0,000 0,01127101 0,02420479 ! T cell homeostasis GO:0043029 20 11 0,000 0,01127101 0,02418221 ! regulation of isotype switching GO:0045191 19 11 0,000 0,01127101 0,02415968 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,01127101 0,02413718 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,01127101 0,02411473 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,01127101 0,02409232 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,01127101 0,02406995 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,01127101 0,02404762 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,01127101 0,02402533 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,01127101 0,02400309 ! male genitalia development GO:0030539 13 11 0,000 0,01127101 0,02398088 ! cholesterol efflux GO:0033344 19 11 0,000 0,01127101 0,02395872 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,01127101 0,0239366 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,01127101 0,02391451 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,01127101 0,02389247 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,01127101 0,02387047 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,01127101 0,02384851 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,01127101 0,02382659 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,01127101 0,02380471 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,01127101 0,02378288 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,01127101 0,02376108 ! lysogeny GO:0030069 18 11 0,000 0,01127101 0,02373932 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,01127101 0,0237176 ! acrosome reaction GO:0007340 13 11 0,000 0,01127101 0,02369592 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,01127101 0,02367428 ! lactation GO:0007595 20 12 0,000 0,01228968 0,02579039 ! reproductive cellular process GO:0048610 14 12 0,000 0,01228968 0,02576688 ! tRNA modification GO:0006400 14 12 0,000 0,01228968 0,02574341 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,01228968 0,02571999 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,01228968 0,02569661 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,01228968 0,02567327 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,01228968 0,02564997 ! non-recombinational repair GO:0000726 19 12 0,000 0,01228968 0,02562672 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,01228968 0,0256035 ! peroxisomal transport GO:0043574 21 12 0,000 0,01228968 0,02558033 ! cartilage condensation GO:0001502 18 12 0,000 0,01228968 0,0255572 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,01228968 0,02553412 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,01228968 0,02551107 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,01228968 0,02548807 ! palate development GO:0060021 15 12 0,000 0,01228968 0,02546511 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,01228968 0,02544218 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,01228968 0,0254193 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,01228968 0,02539647 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,01228968 0,02537367 ! arginine metabolic process GO:0006525 13 12 0,000 0,01228968 0,02535091 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,01228968 0,0253282 ! methionine metabolic process GO:0006555 13 12 0,000 0,01228968 0,02530552 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,01228968 0,02528289 ! Golgi organization GO:0007030 18 12 0,000 0,01228968 0,02526029 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,01228968 0,02523774 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,01228968 0,02521522 ! monoamine transport GO:0015844 13 12 0,000 0,01228968 0,02519275 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01228968 0,02517032 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! neutral amino acid transport GO:0015804 19 12 0,000 0,01228968 0,02514792 ! L-amino acid transport GO:0015807 20 12 0,000 0,01228968 0,02512557 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,01228968 0,02510326 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,01228968 0,02508098 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,01228968 0,02505875 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,01228968 0,02503655 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,01228968 0,0250144 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,01228968 0,02499228 ! cerebellum development GO:0021549 13 12 0,000 0,01228968 0,0249702 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,01228968 0,02494816 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,01228968 0,02492616 ! histone acetylation GO:0016573 23 12 0,000 0,01228968 0,0249042 ! histone methylation GO:0016571 15 12 0,000 0,01228968 0,02488228 ! autonomic nervous system development GO:0048483 23 12 0,000 0,01228968 0,02486039 ! gland morphogenesis GO:0022612 23 12 0,000 0,01228968 0,02483855 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,01228968 0,02481674 ! peptidyl-lysine modification GO:0018205 18 12 0,000 0,01228968 0,02479497 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,01228968 0,02477324 ! response to gamma radiation GO:0010332 20 12 0,000 0,01228968 0,02475155 ! regulation of epidermis development GO:0045682 17 12 0,000 0,01228968 0,02472989 ! intestinal absorption GO:0050892 19 12 0,000 0,01228968 0,02470828 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,01228968 0,0246867 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,01228968 0,02466515 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,01228968 0,02464365 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,01228968 0,02462218 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,01228968 0,02460075 ! microspike assembly GO:0030035 23 12 0,000 0,01228968 0,02457936 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,01228968 0,02455801 ! response to cold GO:0009409 14 12 0,000 0,01228968 0,02453669 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 0,01330736 0,02654546 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,01330736 0,02652246 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,01330736 0,0264995 ! cGMP metabolic process GO:0046068 16 13 0,000 0,01330736 0,02647657 GO:0006182|cGMP biosynthetic process, ! water transport GO:0006833 17 13 0,000 0,01330736 0,02645369 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,01330736 0,02643085 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,01330736 0,02640804 ! lipid localization GO:0010876 24 13 0,000 0,01330736 0,02638528 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,01330736 0,02636255 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,01330736 0,02633986 ! organelle fusion GO:0048284 28 13 0,000 0,01330736 0,02631721 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,01330736 0,0262946 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,01330736 0,02627203 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,01330736 0,0262495 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,01330736 0,02622701 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,01330736 0,02620455 ! response to hexose stimulus GO:0009746 19 13 0,000 0,01330736 0,02618214 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,01330736 0,02615976 ! glutamate metabolic process GO:0006536 18 13 0,000 0,01330736 0,02613742 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,01330736 0,02611512 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,01330736 0,02609286 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,01330736 0,02607063 ! NAD metabolic process GO:0019674 21 13 0,000 0,01330736 0,02604844 ! exocrine system development GO:0035272 27 13 0,000 0,01330736 0,02602629 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,01330736 0,02600418 ! bone mineralization GO:0030282 15 13 0,000 0,01330736 0,02598211 ! regulation of exocytosis GO:0017157 17 13 0,000 0,01330736 0,02596007 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,01330736 0,02593807 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,01330736 0,0259161 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,01330736 0,02589418 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,01330736 0,02587229 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,01330736 0,02585044 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,01330736 0,02582862 ! genitalia development GO:0048806 15 13 0,000 0,01330736 0,02580685 ! regulation of cellular pH GO:0030641 20 13 0,000 0,01330736 0,02578511 ! cellular pigmentation GO:0033059 24 13 0,000 0,01330736 0,0257634 ! tissue regeneration GO:0042246 21 13 0,000 0,01330736 0,02574173 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,01330736 0,0257201 ! cofactor transport GO:0051181 19 13 0,000 0,01330736 0,02569851 ! NADP metabolic process GO:0006739 18 13 0,000 0,01330736 0,02567695 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,01330736 0,02565542 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,01330736 0,02563394 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,01330736 0,02561249 ! gas transport GO:0015669 18 13 0,000 0,01330736 0,02559107 ! heme biosynthetic process GO:0006783 20 13 0,000 0,01330736 0,02556969 ! regulation of axon extension GO:0030516 23 13 0,000 0,01330736 0,02554835 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,01330736 0,02552704 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,01330736 0,02550577 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,01330736 0,02548453 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,01330736 0,02546333 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,01330736 0,02544216 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,01330736 0,02542103 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,01432404 0,02734049 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,01432404 0,02731782 ! superoxide anion generation GO:0042554 18 14 0,000 0,01432404 0,02729519 ! neuron maturation GO:0042551 21 14 0,000 0,01432404 0,0272726 ! regulation of S phase GO:0033261 18 14 0,000 0,01432404 0,02725004 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,01432404 0,02722752 ! myotube differentiation GO:0014902 21 14 0,000 0,01432404 0,02720503 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 0,01432404 0,02718259 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,01432404 0,02716018 ! inositol metabolic process GO:0006020 20 14 0,000 0,01432404 0,0271378 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,01432404 0,02711547 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,01432404 0,02709317 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,01432404 0,02707091 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,01432404 0,02704868 ! gene silencing by RNA GO:0031047 20 14 0,000 0,01432404 0,02702649 ! response to cAMP GO:0051591 19 14 0,000 0,01432404 0,02700434 ! limbic system development GO:0021761 25 14 0,000 0,01432404 0,02698222 ! startle response GO:0001964 21 14 0,000 0,01432404 0,02696014 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,01432404 0,0269381 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,01432404 0,02691609 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,01432404 0,02689412 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,01432404 0,02687218 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,01432404 0,02685028 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,01432404 0,02682842 ! glycine metabolic process GO:0006544 22 14 0,000 0,01432404 0,02680659 ! pituitary gland development GO:0021983 23 14 0,000 0,01432404 0,02678479 ! cellular response to starvation GO:0009267 21 14 0,000 0,01432404 0,02676303 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,01432404 0,02674131 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,01432404 0,02671962 ! regulation of heart rate GO:0002027 23 14 0,000 0,01432404 0,02669797 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,01432404 0,02667635 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,01432404 0,02665477 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,01432404 0,02663322 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,01432404 0,02661171 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,01432404 0,02659023 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,01432404 0,02656879 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,01432404 0,02654738 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,01432404 0,026526 ! axon cargo transport GO:0008088 27 14 0,000 0,01432404 0,02650466 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,01432404 0,02648336 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,01432404 0,02646208 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,01432404 0,02644085 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,01432404 0,02641964 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,01432404 0,02639847 ! mRNA splice site selection GO:0006376 26 14 0,000 0,01432404 0,02637734 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,01432404 0,02635624 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,01432404 0,02633517 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,01432404 0,02631413 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,01432404 0,02629313 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,01432404 0,02627216 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,01432404 0,02625123 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,01432404 0,02623033 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,01432404 0,02620946 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,01432404 0,02618863 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,01432404 0,02616783 ! cell killing GO:0001906 20 14 0,000 0,01432404 0,02614706 ! release of cytochrome c from mitochondria GO:0001836 23 14 0,000 0,01432404 0,02612632 ! cilium assembly GO:0042384 20 14 0,000 0,01432404 0,02610562 ! peptide hormone secretion GO:0030072 23 14 0,000 0,01432404 0,02608495 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,01533974 0,0279125 ! positive regulation of cell size GO:0045793 20 15 0,000 0,01533974 0,02789043 ! metencephalon development GO:0022037 19 15 0,000 0,01533974 0,0278684 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,01533974 0,0278464 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,01533974 0,02782444 ! skin development GO:0043588 25 15 0,000 0,01533974 0,02780252 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,01533974 0,02778063 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,01533974 0,02775877 ! lipid phosphorylation GO:0046834 23 15 0,000 0,01533974 0,02773695 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,01533974 0,02771516 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,01533974 0,0276934 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,01533974 0,02767168 ! bile acid metabolic process GO:0008206 22 15 0,000 0,01533974 0,02765 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,01533974 0,02762834 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,01533974 0,02760672 ! adult walking behavior GO:0007628 25 15 0,000 0,01533974 0,02758514 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,01533974 0,02756359 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,01533974 0,02754207 ! myoblast differentiation GO:0045445 27 15 0,000 0,01533974 0,02752059 ! centrosome cycle GO:0007098 16 15 0,000 0,01533974 0,02749914 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,01533974 0,02747772 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,01533974 0,02745634 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,01533974 0,02743499 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,01533974 0,02741367 ! cerebral cortex development GO:0021987 29 15 0,000 0,01533974 0,02739239 ! response to osmotic stress GO:0006970 22 15 0,000 0,01533974 0,02737114 ! vesicle coating GO:0006901 25 15 0,000 0,01533974 0,02734992 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,01533974 0,02732873 ! DNA integration GO:0015074 22 15 0,000 0,01533974 0,02730758 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,01533974 0,02728646 ! peptide secretion GO:0002790 27 15 0,000 0,01533974 0,02726537 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,01533974 0,02724432 ! regulation of vasodilation GO:0042312 24 15 0,000 0,01533974 0,0272233 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,01533974 0,02720231 ! neuron recognition GO:0008038 22 15 0,000 0,01533974 0,02718135 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,01533974 0,02716043 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,01533974 0,02713953 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,01533974 0,02711867 ! biomineral formation GO:0031214 18 15 0,000 0,01533974 0,02709785 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,01533974 0,02707705 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,01533974 0,02705628 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,01533974 0,02703555 ! dopamine metabolic process GO:0042417 30 15 0,000 0,01533974 0,02701485 ! organic cation transport GO:0015695 19 15 0,000 0,01533974 0,02699418 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,01533974 0,02697354 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,01533974 0,02695294 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,01533974 0,02693236 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,01533974 0,02691182 ! defense response to virus GO:0051607 27 15 0,000 0,01533974 0,02689131 ! peptide hormone processing GO:0016486 19 15 0,000 0,01533974 0,02687083 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,01533974 0,02685038 ! protein secretion GO:0009306 27 16 0,000 0,01635444 0,02860473 ! hormone secretion GO:0046879 25 16 0,000 0,01635444 0,02858299 ! bone remodeling GO:0046849 24 16 0,000 0,01635444 0,02856129 ! endothelial cell migration GO:0043542 22 16 0,000 0,01635444 0,02853962 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,01635444 0,02851798 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,01635444 0,02849638 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,01635444 0,02847481 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,01635444 0,02845327 ! glial cell development GO:0021782 24 16 0,000 0,01635444 0,02843176 ! patterning of blood vessels GO:0001569 24 16 0,000 0,01635444 0,02841029 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,01635444 0,02838885 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,01635444 0,02836744 ! protein polyubiquitination GO:0000209 26 16 0,000 0,01635444 0,02834606 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,01635444 0,02832471 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,01635444 0,0283034 ! fructose metabolic process GO:0006000 20 16 0,000 0,01635444 0,02828212 ! regulation of protein binding GO:0043393 27 16 0,000 0,01635444 0,02826087 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,01635444 0,02823965 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,01635444 0,02821847 ! protein export from nucleus GO:0006611 24 16 0,000 0,01635444 0,02819732 ! negative regulation of immune response GO:0050777 28 16 0,000 0,01635444 0,02817619 ! DNA replication initiation GO:0006270 25 16 0,000 0,01635444 0,0281551 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,01635444 0,02813405 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,01635444 0,02811302 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,01635444 0,02809202 ! diencephalon development GO:0021536 25 16 0,000 0,01635444 0,02807106 ! oogenesis GO:0048477 23 16 0,000 0,01635444 0,02805013 ! G1 phase GO:0051318 27 16 0,000 0,01635444 0,02802923 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,01635444 0,02800835 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,01635444 0,02798751 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,01635444 0,02796671 ! steroid catabolic process GO:0006706 22 16 0,000 0,01635444 0,02794593 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,01635444 0,02792518 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,01635444 0,02790447 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,01635444 0,02788378 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,01635444 0,02786313 ! sperm-egg recognition GO:0035036 16 16 0,000 0,01635444 0,0278425 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,01635444 0,02782191 ! nerve development GO:0021675 18 16 0,000 0,01635444 0,02780135 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,01635444 0,02778081 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,01635444 0,02776031 ! negative regulation of translation GO:0017148 22 16 0,000 0,01635444 0,02773984 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,01736816 0,02943756 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,01736816 0,02941589 ! negative regulation of defense response GO:0031348 19 17 0,000 0,01736816 0,02939424 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,01736816 0,02937263 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,01736816 0,02935105 ! glycerol metabolic process GO:0006071 20 17 0,000 0,01736816 0,0293295 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,01736816 0,02930798 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,01736816 0,02928649 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,01736816 0,02926504 ! signal complex assembly GO:0007172 29 17 0,000 0,01736816 0,02924361 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,01736816 0,02922222 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,01736816 0,02920086 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,01736816 0,02917953 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,01736816 0,02915823 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,01736816 0,02913696 ! memory GO:0007613 25 17 0,000 0,01736816 0,02911572 ! keratinization GO:0031424 17 17 0,000 0,01736816 0,02909452 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,01736816 0,02907334 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,01736816 0,0290522 ! retinoid metabolic process GO:0001523 22 17 0,000 0,01736816 0,02903109 GO:0016101|diterpenoid metabolic process, ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,01736816 0,02901 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,01736816 0,02898895 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,01736816 0,02896793 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,01736816 0,02894694 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,01736816 0,02892598 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 0,000 0,01736816 0,02890505 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,01736816 0,02888415 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,01736816 0,02886328 ! membrane budding GO:0006900 29 17 0,000 0,01736816 0,02884244 ! heme metabolic process GO:0042168 27 17 0,000 0,01736816 0,02882163 ! actin filament bundle formation GO:0051017 26 17 0,000 0,01736816 0,02880085 ! neuromuscular junction development GO:0007528 23 17 0,000 0,01736816 0,0287801 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,01736816 0,02875938 ! body fluid secretion GO:0007589 27 17 0,000 0,01736816 0,02873869 ! stem cell differentiation GO:0048863 36 17 0,000 0,01736816 0,02871803 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,01736816 0,0286974 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,01736816 0,02867679 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,01736816 0,02865622 ! sensory perception of pain GO:0019233 23 17 0,000 0,01736816 0,02863568 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,01736816 0,02861517 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,01736816 0,02859468 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,01736816 0,02857423 ! synaptogenesis GO:0007416 24 17 0,000 0,01736816 0,02855381 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,01736816 0,02853341 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,01736816 0,02851304 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,01736816 0,02849271 ! cell-cell junction organization GO:0045216 25 17 0,000 0,01736816 0,0284724 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,01736816 0,02845212 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,01736816 0,02843187 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,01736816 0,02841165 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,01736816 0,02839145 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,01736816 0,02837129 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,0183809 0,0300043 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,0183809 0,02998302 ! positive regulation of translation GO:0045727 28 18 0,000 0,0183809 0,02996177 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,0183809 0,02994055 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,0183809 0,02991936 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,0183809 0,0298982 ! cAMP metabolic process GO:0046058 33 18 0,000 0,0183809 0,02987707 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,0183809 0,02985597 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,0183809 0,0298349 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,0183809 0,02981386 ! axis specification GO:0009798 26 18 0,000 0,0183809 0,02979285 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,0183809 0,02977187 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,0183809 0,02975092 ! pancreas development GO:0031016 26 18 0,000 0,0183809 0,02973 ! apoptotic mitochondrial changes GO:0008637 29 18 0,000 0,0183809 0,02970911 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,0183809 0,02968824 ! glutamine metabolic process GO:0006541 23 18 0,000 0,0183809 0,02966741 ! response to retinoic acid GO:0032526 25 18 0,000 0,0183809 0,02964661 ! pigmentation during development GO:0048066 31 18 0,000 0,0183809 0,02962583 ! central nervous system neuron development GO:0021954 30 18 0,000 0,0183809 0,02960508 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,0183809 0,02958437 ! fucose metabolic process GO:0006004 26 18 0,000 0,0183809 0,02956368 ! response to fungus GO:0009620 19 18 0,000 0,0183809 0,02954302 ! peptide cross-linking GO:0018149 31 18 0,000 0,0183809 0,02952239 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,0183809 0,02950179 ! heart process GO:0003015 27 18 0,000 0,0183809 0,02948121 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,0183809 0,02946067 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,0183809 0,02944015 ! visual learning GO:0008542 35 18 0,000 0,0183809 0,02941967 ! somitogenesis GO:0001756 24 18 0,000 0,0183809 0,02939921 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,0183809 0,02937878 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,0183809 0,02935837 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,0183809 0,029338 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,0183809 0,02931766 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,0183809 0,02929734 ! vitamin transport GO:0051180 24 18 0,000 0,0183809 0,02927705 ! hormone transport GO:0009914 27 18 0,000 0,0183809 0,02925679 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,0183809 0,02923656 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,0183809 0,02921635 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,0183809 0,02919617 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,0183809 0,02917602 ! cell-cell recognition GO:0009988 20 18 0,000 0,0183809 0,0291559 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,0183809 0,02913581 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,0183809 0,02911574 ! regulation of glucose import GO:0046324 21 18 0,000 0,0183809 0,0290957 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,0183809 0,02907569 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,0183809 0,02905571 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,0183809 0,02903575 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,01939264 0,03061296 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,01939264 0,03059196 ! positive regulation of fibroblast proliferation GO:0048146 27 19 0,000 0,01939264 0,03057099 ! positive regulation of ossification GO:0045778 30 19 0,000 0,01939264 0,03055005 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,01939264 0,03052914 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,01939264 0,03050826 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,01939264 0,03048741 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,01939264 0,03046658 ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,01939264 0,03044579 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,01939264 0,03042502 ! regeneration GO:0031099 32 19 0,000 0,01939264 0,03040428 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,01939264 0,03038357 ! response to alkaloid GO:0043279 32 19 0,000 0,01939264 0,03036288 ! sensory perception of taste GO:0050909 23 19 0,000 0,01939264 0,03034223 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,01939264 0,0303216 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 0,000 0,01939264 0,030301 ! smooth muscle contraction GO:0006939 36 19 0,000 0,01939264 0,03028043 ! peroxisome organization GO:0007031 29 19 0,000 0,01939264 0,03025989 ! digestive system process GO:0022600 30 19 0,000 0,01939264 0,03023937 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,01939264 0,03021889 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,01939264 0,03019843 ! response to vitamin A GO:0033189 26 19 0,000 0,01939264 0,03017799 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,01939264 0,03015759 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,01939264 0,03013721 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,01939264 0,03011686 ! response to starvation GO:0042594 30 19 0,000 0,01939264 0,03009654 ! sex determination GO:0007530 29 19 0,000 0,01939264 0,03007625 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,01939264 0,03005598 ! plasma membrane fusion GO:0045026 23 19 0,000 0,01939264 0,03003574 ! cytolysis GO:0019835 20 19 0,000 0,01939264 0,03001553 ! renal system process GO:0003014 35 19 0,000 0,01939264 0,02999534 ! vasodilation GO:0042311 33 19 0,000 0,01939264 0,02997519 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,01939264 0,02995505 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,01939264 0,02993495 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,01939264 0,02991487 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,01939264 0,02989482 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,01939264 0,0298748 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,01939264 0,0298548 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,01939264 0,02983483 ! sarcomere organization GO:0045214 23 19 0,000 0,01939264 0,02981489 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,01939264 0,02979497 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,01939264 0,02977508 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,01939264 0,02975522 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,01939264 0,02973538 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,01939264 0,02971557 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,01939264 0,02969579 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,01939264 0,02967603 ! protein stabilization GO:0050821 26 19 0,000 0,01939264 0,0296563 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,0204034 0,03118128 ! iron ion transport GO:0006826 37 20 0,000 0,0204034 0,03116058 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,0204034 0,0311399 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,0204034 0,03111925 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,0204034 0,03109863 ! response to vitamin GO:0033273 29 20 0,000 0,0204034 0,03107803 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,0204034 0,03105746 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,0204034 0,03103692 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,0204034 0,03101641 ! spinal cord development GO:0021510 31 20 0,000 0,0204034 0,03099592 ! response to ethanol GO:0045471 37 20 0,000 0,0204034 0,03097546 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,0204034 0,03095503 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 0,000 0,0204034 0,03093463 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,0204034 0,03091425 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,0204034 0,0308939 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,0204034 0,03087357 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,0204034 0,03085327 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,0204034 0,030833 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,0204034 0,03081276 ! pallium development GO:0021543 38 20 0,000 0,0204034 0,03079254 ! DNA modification GO:0006304 28 20 0,000 0,0204034 0,03077235 ! collagen fibril organization GO:0030199 45 20 0,000 0,0204034 0,03075218 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,0204034 0,03073204 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,0204034 0,03071193 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,0204034 0,03069184 ! positive regulation of B cell activation GO:0050871 31 20 0,000 0,0204034 0,03067178 ! collagen catabolic process GO:0030574 25 20 0,000 0,0204034 0,03065175 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,0204034 0,03063174 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,0204034 0,03061176 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,0204034 0,0305918 ! alditol metabolic process GO:0019400 24 20 0,000 0,0204034 0,03057188 ! actin filament-based movement GO:0030048 34 20 0,000 0,0204034 0,03055197 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,02141318 0,03204315 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,02141318 0,03202231 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,02141318 0,03200151 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,02141318 0,03198073 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 0,000 0,02141318 0,03195997 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,02141318 0,03193925 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,02141318 0,03191855 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,02141318 0,03189787 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,02141318 0,03187723 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,02141318 0,03185661 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,02141318 0,03183602 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,02141318 0,03181545 ! protein amino acid acylation GO:0043543 37 21 0,000 0,02141318 0,03179491 ! vesicle docking GO:0048278 27 21 0,000 0,02141318 0,0317744 ! phototransduction GO:0007602 25 21 0,000 0,02141318 0,03175391 ! dendrite development GO:0016358 35 21 0,000 0,02141318 0,03173345 ! visual behavior GO:0007632 39 21 0,000 0,02141318 0,03171302 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,02141318 0,03169261 ! ovarian follicle development GO:0001541 30 21 0,000 0,02141318 0,03167223 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,02141318 0,03165187 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,02141318 0,03163155 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,02141318 0,03161124 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,02141318 0,03159097 ! cell aging GO:0007569 32 21 0,000 0,02141318 0,03157072 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,02141318 0,03155049 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,02141318 0,03153029 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,02141318 0,03151012 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,02141318 0,03148997 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,02141318 0,03146985 GO:0060415|muscle tissue morphogenesis, ! leukotriene metabolic process GO:0006691 28 21 0,000 0,02141318 0,03144976 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,02141318 0,03142969 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,02141318 0,03140964 ! fatty acid transport GO:0015908 30 21 0,000 0,02141318 0,03138962 ! immunoglobulin production GO:0002377 33 21 0,000 0,02141318 0,03136963 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,02141318 0,03134966 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,02141318 0,03132972 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,02141318 0,0313098 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,02141318 0,03128991 ! cellular response to extracellular stimulus GO:0031668 32 21 0,000 0,02141318 0,03127004 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,02141318 0,0312502 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,02141318 0,03123039 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,02141318 0,03121059 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,02141318 0,03119083 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,02141318 0,03117109 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,02141318 0,03115137 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,02141318 0,03113168 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,02141318 0,03111201 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,02141318 0,03109237 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,02141318 0,03107276 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,02242198 0,03251611 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,02242198 0,03249562 ! regulation of fibroblast proliferation GO:0048145 35 22 0,000 0,02242198 0,03247515 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,02242198 0,03245472 ! viral genome replication GO:0019079 29 22 0,000 0,02242198 0,0324343 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,02242198 0,03241392 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,02242198 0,03239356 ! leukocyte adhesion GO:0007159 38 22 0,000 0,02242198 0,03237322 ! molting cycle process GO:0022404 40 22 0,000 0,02242198 0,03235291 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,02242198 0,03233263 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,02242198 0,03231237 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,02242198 0,03229214 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,02242198 0,03227193 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,02242198 0,03225175 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,02242198 0,03223159 GO:0010810|regulation of cell-substrate adhesion, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,02242198 0,03221146 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,02242198 0,03219135 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,02242198 0,03217127 ! lysosome organization GO:0007040 37 22 0,000 0,02242198 0,03215121 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,02242198 0,03213118 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,02242198 0,03211117 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,02242198 0,03209119 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,02242198 0,03207123 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,02242198 0,0320513 ! membrane depolarization GO:0051899 35 22 0,000 0,02242198 0,03203139 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,02242198 0,03201151 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,02242198 0,03199165 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,02242198 0,03197182 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,02242198 0,03195201 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,02242198 0,03193223 ! blastocyst development GO:0001824 37 22 0,000 0,02242198 0,03191247 ! neural tube closure GO:0001843 33 22 0,000 0,02242198 0,03189273 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,02242198 0,03187302 ! protein tetramerization GO:0051262 39 22 0,000 0,02242198 0,03185333 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,02342979 0,03326451 ! neuron fate commitment GO:0048663 32 23 0,000 0,02342979 0,03324399 ! embryonic pattern specification GO:0009880 31 23 0,000 0,02342979 0,0332235 ! positive regulation of cell adhesion GO:0045785 37 23 0,000 0,02342979 0,03320303 ! myelination GO:0042552 35 23 0,000 0,02342979 0,03318258 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,02342979 0,03316216 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,02342979 0,03314177 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,02342979 0,0331214 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,02342979 0,03310105 ! vesicle targeting GO:0006903 32 23 0,000 0,02342979 0,03308073 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,02342979 0,03306044 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,02342979 0,03304017 ! osteoblast differentiation GO:0001649 40 23 0,000 0,02342979 0,03301992 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,02342979 0,0329997 ! interaction with host GO:0051701 37 23 0,000 0,02342979 0,03297951 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,02342979 0,03295934 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,02342979 0,03293919 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,02342979 0,03291907 ! negative regulation of phosphorylation GO:0042326 41 23 0,000 0,02342979 0,03289897 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,02342979 0,0328789 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,02342979 0,03285885 ! cell fate determination GO:0001709 45 23 0,000 0,02342979 0,03283883 ! pentose metabolic process GO:0019321 31 23 0,000 0,02342979 0,03281883 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,02342979 0,03279885 ! spermatid development GO:0007286 33 23 0,000 0,02342979 0,0327789 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,02342979 0,03275897 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,02342979 0,03273907 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,02342979 0,03271919 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,02342979 0,03269934 ! telomere organization GO:0032200 32 23 0,000 0,02342979 0,03267951 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,02342979 0,03265971 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,02342979 0,03263992 ! regulation of amine transport GO:0051952 38 23 0,000 0,02342979 0,03262017 ! liver development GO:0001889 40 23 0,000 0,02342979 0,03260043 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,02443662 0,03398079 ! initiation of viral infection GO:0019059 42 24 0,000 0,02443662 0,03396026 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,02443662 0,03393975 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,02443662 0,03391927 ! superoxide metabolic process GO:0006801 32 24 0,000 0,02443662 0,03389881 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,02443662 0,03387838 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! insulin receptor signaling pathway GO:0008286 40 24 0,000 0,02443662 0,03385797 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,02443662 0,03383758 ! sperm motility GO:0030317 27 24 0,000 0,02443662 0,03381722 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,02443662 0,03379689 ! vacuole organization GO:0007033 39 24 0,000 0,02443662 0,03377658 ! receptor metabolic process GO:0043112 37 24 0,000 0,02443662 0,03375629 ! response to toxin GO:0009636 38 24 0,000 0,02443662 0,03373603 ! primary neural tube formation GO:0014020 35 24 0,000 0,02443662 0,03371579 ! negative regulation of cell development GO:0010721 56 24 0,000 0,02443662 0,03369558 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,02443662 0,03367539 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,02443662 0,03365522 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,02443662 0,03363508 ! glutathione metabolic process GO:0006749 29 24 0,000 0,02443662 0,03361497 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,02443662 0,03359487 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,02443662 0,03357481 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,02443662 0,03355476 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,02544247 0,03491508 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,02544247 0,03489426 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,02544247 0,03487347 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,02544247 0,0348527 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,02544247 0,03483195 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,02544247 0,03481123 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 0,000 0,02544247 0,03479054 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,02544247 0,03476986 ! peptide transport GO:0015833 43 25 0,000 0,02544247 0,03474922 ! male gonad development GO:0008584 33 25 0,000 0,02544247 0,03472859 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,02544247 0,034708 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,02544247 0,03468742 ! phospholipid transport GO:0015914 35 25 0,000 0,02544247 0,03466687 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,02544247 0,03464635 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,02544247 0,03462585 ! detection of light stimulus GO:0009583 30 25 0,000 0,02544247 0,03460537 ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,02544247 0,03458492 ! leukocyte proliferation GO:0070661 39 25 0,000 0,02544247 0,03456449 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,02544247 0,03454409 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,02644734 0,03588725 ! translational initiation GO:0006413 43 26 0,000 0,02644734 0,03586609 ! regulation of pH GO:0006885 36 26 0,000 0,02644734 0,03584495 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 0,000 0,02644734 0,03582384 ! circadian rhythm GO:0007623 42 26 0,000 0,02644734 0,03580276 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,02644734 0,0357817 ! post-embryonic development GO:0009791 42 26 0,000 0,02644734 0,03576066 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,02644734 0,03573965 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,02644734 0,03571866 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,02644734 0,0356977 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,02644734 0,03567677 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,02644734 0,03565585 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,02644734 0,03563496 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,02644734 0,0356141 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,02644734 0,03559326 ! regulation of coagulation GO:0050818 39 26 0,000 0,02644734 0,03557245 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,02745123 0,03690113 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,02745123 0,03687958 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,02745123 0,03685805 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,02745123 0,03683654 ! membrane docking GO:0022406 39 27 0,000 0,02745123 0,03681507 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,02745123 0,03679361 ! catechol metabolic process GO:0009712 43 27 0,000 0,02745123 0,03677218 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,02745123 0,03675078 ! acute-phase response GO:0006953 42 27 0,000 0,02745123 0,0367294 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,02745123 0,03670805 ! myofibril assembly GO:0030239 36 27 0,000 0,02745123 0,03668672 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,02745123 0,03666541 ! response to ionizing radiation GO:0010212 47 27 0,000 0,02745123 0,03664413 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,02745123 0,03662288 ! natural killer cell activation GO:0030101 35 27 0,000 0,02745123 0,03660165 ! lipid oxidation GO:0034440 38 27 0,000 0,02745123 0,03658044 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,02745123 0,03655926 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,02745123 0,0365381 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,02745123 0,03651697 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,02745123 0,03649586 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,02745123 0,03647478 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,02745123 0,03645372 ! gene silencing GO:0016458 41 27 0,000 0,02745123 0,03643268 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,02845415 0,03774195 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,02845415 0,0377202 ! phenol metabolic process GO:0018958 44 28 0,000 0,02845415 0,03769847 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,02845415 0,03767677 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,02845415 0,03765509 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,02845415 0,03763343 ! cell junction assembly GO:0034329 56 28 0,000 0,02845415 0,03761181 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,02845415 0,0375902 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,02845415 0,03756862 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,02845415 0,03754707 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,02845415 0,03752554 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,02845415 0,03750404 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,02845415 0,03748256 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,02845415 0,0374611 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,02845415 0,03743967 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,02845415 0,03741826 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,02845415 0,03739688 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,02845415 0,03737552 ! mesoderm formation GO:0001707 46 28 0,000 0,02845415 0,03735419 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,02845415 0,03733288 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,02845415 0,0373116 ! ensheathment of neurons GO:0007272 43 28 0,000 0,02845415 0,03729034 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,02845415 0,0372691 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,02845415 0,03724789 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,02845415 0,0372267 ! neural tube formation GO:0001841 41 28 0,000 0,02845415 0,03720554 ! regulation of B cell activation GO:0050864 42 28 0,000 0,02845415 0,0371844 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,02945609 0,03847189 ! regulation of innate immune response GO:0045088 38 29 0,000 0,02945609 0,03845006 ! ovulation cycle process GO:0022602 41 29 0,000 0,02945609 0,03842825 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,02945609 0,03840646 ! protein targeting to membrane GO:0006612 53 29 0,000 0,02945609 0,0383847 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,02945609 0,03836297 ! mismatch repair GO:0006298 34 29 0,000 0,02945609 0,03834126 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,02945609 0,03831957 ! muscle cell development GO:0055001 38 29 0,000 0,02945609 0,03829791 ! formation of primary germ layer GO:0001704 48 29 0,000 0,02945609 0,03827627 ! telencephalon development GO:0021537 52 29 0,000 0,02945609 0,03825466 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,02945609 0,03823307 ! eye morphogenesis GO:0048592 51 29 0,000 0,02945609 0,03821151 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,02945609 0,03818997 ! tissue homeostasis GO:0001894 42 29 0,000 0,02945609 0,03816845 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,03045705 0,03944325 ! organic anion transport GO:0015711 51 30 0,000 0,03045705 0,03942105 ! cholesterol transport GO:0030301 46 30 0,000 0,03045705 0,03939888 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,03045705 0,03937674 ! spliceosome assembly GO:0000245 49 30 0,000 0,03045705 0,03935461 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,03045705 0,03933252 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,03045705 0,03931044 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,03045705 0,0392884 ! ceramide metabolic process GO:0006672 43 30 0,000 0,03045705 0,03926637 ! ovulation cycle GO:0042698 43 30 0,000 0,03045705 0,03924438 ! hindbrain development GO:0030902 45 30 0,000 0,03045705 0,0392224 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,03045705 0,03920045 ! adult locomotory behavior GO:0008344 47 30 0,000 0,03045705 0,03917853 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,03045705 0,03915663 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,03045705 0,03913476 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,03045705 0,0391129 ! response to heat GO:0009408 41 30 0,000 0,03045705 0,03909108 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,03045705 0,03906928 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,03045705 0,0390475 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,03145704 0,04030707 ! negative regulation of secretion GO:0051048 49 31 0,000 0,03145704 0,04028462 ! mammary gland development GO:0030879 57 31 0,000 0,03145704 0,0402622 ! glial cell differentiation GO:0010001 55 31 0,000 0,03145704 0,04023981 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,03145704 0,04021744 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,03145704 0,0401951 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,03145704 0,04017278 ! odontogenesis GO:0042476 50 31 0,000 0,03145704 0,04015049 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,03145704 0,04012822 ! segmentation GO:0035282 41 31 0,000 0,03145704 0,04010598 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,03145704 0,04008376 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,03145704 0,04006156 ! metanephros development GO:0001656 58 31 0,000 0,03145704 0,04003939 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,03145704 0,04001725 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,03145704 0,03999513 ! cell fate specification GO:0001708 37 31 0,000 0,03145704 0,03997303 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,03145704 0,03995096 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,03145704 0,03992891 ! RNA modification GO:0009451 40 31 0,000 0,03145704 0,03990688 ! regulation of muscle development GO:0048634 48 32 0,000 0,03245605 0,04115155 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,03245605 0,04112888 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,03245605 0,04110623 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,03245605 0,04108361 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,03245605 0,04106101 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,03245605 0,04103843 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,03245605 0,04101589 ! peripheral nervous system development GO:0007422 53 32 0,000 0,03245605 0,04099336 ! regulation of protein stability GO:0031647 48 32 0,000 0,03245605 0,04097086 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,03245605 0,04094839 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,03245605 0,04092594 ! cytokine production GO:0001816 44 32 0,000 0,03245605 0,04090351 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,03245605 0,04088111 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,03245605 0,04085874 ! vesicle localization GO:0051648 47 32 0,000 0,03245605 0,04083638 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,03345409 0,04206911 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,03345409 0,04204612 ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,03345409 0,04202316 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,03345409 0,04200022 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,03345409 0,04197731 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,03345409 0,04195442 ! ear morphogenesis GO:0042471 42 33 0,000 0,03345409 0,04193155 ! actomyosin structure organization GO:0031032 43 33 0,000 0,03345409 0,04190872 ! cell junction organization GO:0034330 63 33 0,000 0,03345409 0,0418859 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,03345409 0,04186311 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,03345409 0,04184035 ! female gonad development GO:0008585 49 33 0,000 0,03345409 0,04181761 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,03345409 0,0417949 ! positive regulation of cell development GO:0010720 54 33 0,000 0,03345409 0,04177221 ! lipid homeostasis GO:0055088 55 33 0,000 0,03345409 0,04174954 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,03345409 0,0417269 ! regulation of proteolysis GO:0030162 50 33 0,000 0,03345409 0,04170428 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,03345409 0,04168169 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,03345409 0,04165912 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,03345409 0,04163658 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,03345409 0,04161406 ! mRNA catabolic process GO:0006402 48 34 0,000 0,03445116 0,04283117 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,03445116 0,04280803 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,03445116 0,04278491 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,03445116 0,04276182 ! feeding behavior GO:0007631 45 34 0,000 0,03445116 0,04273876 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,03445116 0,04271572 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,03445116 0,0426927 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,03445116 0,04266971 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,03445116 0,04264675 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,03445116 0,04262381 ! neuron migration GO:0001764 46 34 0,000 0,03445116 0,04260089 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,03445116 0,042578 ! female gamete generation GO:0007292 43 34 0,000 0,03445116 0,04255513 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,03445116 0,04253229 ! polyol metabolic process GO:0019751 44 34 0,000 0,03445116 0,04250947 ! aerobic respiration GO:0009060 47 34 0,000 0,03445116 0,04248668 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,03445116 0,04246391 ! cellular response to insulin stimulus GO:0032869 52 34 0,000 0,03445116 0,04244117 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,03445116 0,04241845 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,03544725 0,04362155 ! Notch signaling pathway GO:0007219 56 35 0,000 0,03544725 0,04359822 ! regulation of intracellular protein transport GO:0033157 59 35 0,000 0,03544725 0,04357492 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,03544725 0,04355164 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,03544725 0,04352839 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,03544725 0,04350516 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,03544725 0,04348196 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,03544725 0,04345878 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,03544725 0,04343563 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,03544725 0,0434125 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,03544725 0,0433894 ! glycogen metabolic process GO:0005977 48 35 0,000 0,03544725 0,04336632 ! pigment metabolic process GO:0042440 61 35 0,000 0,03544725 0,04334326 ! positive regulation of leukocyte proliferation GO:0070665 50 35 0,000 0,03544725 0,04332023 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! protein homooligomerization GO:0051260 52 35 0,000 0,03544725 0,04329723 ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,03644238 0,0444891 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 0,000 0,03644238 0,0444655 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,03644238 0,04444192 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,03644238 0,04441837 ! negative regulation of binding GO:0051100 58 36 0,000 0,03644238 0,04439484 ! organic ether metabolic process GO:0018904 46 36 0,000 0,03644238 0,04437134 ! neural tube development GO:0021915 50 36 0,000 0,03644238 0,04434787 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,03644238 0,04432441 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,03644238 0,04430099 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,03644238 0,04427758 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,03644238 0,04425421 ! glucan metabolic process GO:0044042 49 36 0,000 0,03644238 0,04423085 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,03743653 0,04541351 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,03743653 0,04538957 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,03743653 0,04536566 ! learning GO:0007612 67 37 0,000 0,03743653 0,04534177 ! ion transmembrane transport GO:0034220 56 37 0,000 0,03743653 0,04531791 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,03743653 0,04529407 ! regulation of protein secretion GO:0050708 51 37 0,000 0,03743653 0,04527025 ! amino acid activation GO:0043038 52 37 0,000 0,03743653 0,04524647 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,03743653 0,0452227 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,03842972 0,04639809 ! gliogenesis GO:0042063 71 38 0,000 0,03842972 0,04637374 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,03842972 0,04634942 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,03842972 0,04632513 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,03842972 0,04630087 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,03842972 0,04627662 ! phagocytosis GO:0006909 60 38 0,000 0,03842972 0,04625241 ! pigmentation GO:0043473 74 38 0,000 0,03842972 0,04622822 ! maintenance of location in cell GO:0051651 69 38 0,000 0,03842972 0,04620405 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,03942194 0,04737223 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,03942194 0,0473475 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,03942194 0,04732278 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,03942194 0,0472981 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,03942194 0,04727344 ! regulation of epithelial cell proliferation GO:0050678 71 39 0,000 0,03942194 0,0472488 ! male sex differentiation GO:0046661 53 39 0,000 0,03942194 0,0472242 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,03942194 0,04719961 ! chromatin remodeling GO:0006338 68 39 0,000 0,03942194 0,04717506 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,03942194 0,04715052 ! JNK cascade GO:0007254 54 39 0,000 0,03942194 0,04712602 ! developmental growth GO:0048589 62 39 0,000 0,03942194 0,04710154 ! cell growth GO:0016049 61 39 0,000 0,03942194 0,04707708 ! synapse organization GO:0050808 55 39 0,000 0,03942194 0,04705265 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,04041319 0,04821075 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,04041319 0,04818576 ! regulation of tube size GO:0035150 60 40 0,000 0,04041319 0,0481608 GO:0050880|regulation of blood vessel size, ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,04041319 0,04813585 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,04041319 0,04811094 ! peptide metabolic process GO:0006518 56 40 0,000 0,04041319 0,04808605 ! induction of apoptosis by intracellular signals GO:0008629 67 40 0,000 0,04041319 0,04806119 ! inner ear development GO:0048839 57 40 0,000 0,04041319 0,04803635 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,04041319 0,04801154 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,04041319 0,04798675 ! double-strand break repair GO:0006302 67 40 0,000 0,04041319 0,04796199 ! B cell differentiation GO:0030183 62 40 0,000 0,04041319 0,04793725 ! epidermal cell differentiation GO:0009913 53 40 0,000 0,04041319 0,04791254 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,04041319 0,04788786 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,04041319 0,0478632 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,04140347 0,0490108 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,04140347 0,04898559 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,04140347 0,04896041 ! glucose transport GO:0015758 52 41 0,000 0,04140347 0,04893525 ! endosome transport GO:0016197 71 41 0,000 0,04140347 0,04891011 ! striated muscle contraction GO:0006941 62 41 0,000 0,04140347 0,04888501 ! positive regulation of DNA binding GO:0043388 57 41 0,000 0,04140347 0,04885992 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,04140347 0,04883487 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,04140347 0,04880984 ! biopolymer methylation GO:0043414 62 41 0,000 0,04140347 0,04878483 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,04140347 0,04875985 ! mitochondrial transport GO:0006839 60 42 0,000 0,0423928 0,0498994 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,0423928 0,04987388 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 0,000 0,0423928 0,04984838 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,0423928 0,04982291 ! cellular component disassembly GO:0022411 64 42 0,000 0,0423928 0,04979746 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,0423928 0,04977204 ! hexose transport GO:0008645 54 42 0,000 0,0423928 0,04974665 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,0423928 0,04972128 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,0423928 0,04969594 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,0423928 0,04967062 ! excretion GO:0007588 63 42 0,000 0,0423928 0,04964533 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,0423928 0,04962007 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,0423928 0,04959483 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,0423928 0,04956961 ! positive regulation of binding GO:0051099 59 43 0,000 0,04338115 0,05069952 ! leukocyte migration GO:0050900 60 43 0,000 0,04338115 0,05067377 ! neuromuscular process GO:0050905 79 43 0,000 0,04338115 0,05064804 ! activation of caspase activity GO:0006919 65 43 0,000 0,04338115 0,05062235 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,04338115 0,05059668 ! tRNA processing GO:0008033 49 43 0,000 0,04338115 0,05057103 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,04338115 0,05054541 ! vesicle organization GO:0016050 79 43 0,000 0,04338115 0,05051982 ! response to insulin stimulus GO:0032868 63 43 0,000 0,04338115 0,05049426 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,04338115 0,05046871 ! methylation GO:0032259 64 43 0,000 0,04338115 0,0504432 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,04436854 0,05156526 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,04436854 0,05153922 ! glycolysis GO:0006096 53 44 0,000 0,04436854 0,0515132 ! regulation of action potential GO:0001508 71 44 0,000 0,04436854 0,05148721 ! regulation of ion transport GO:0043269 57 44 0,000 0,04436854 0,05146125 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,04436854 0,05143531 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,04436854 0,0514094 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,04436854 0,05138351 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,04436854 0,05135765 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,04436854 0,05133182 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,04436854 0,05130601 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,04436854 0,05128023 ! regulation of mast cell proliferation GO:0070666 64 44 0,000 0,04436854 0,05125447 ! RNA catabolic process GO:0006401 64 45 0,000 0,04535497 0,05236769 ! positive regulation of defense response GO:0031349 59 45 0,000 0,04535497 0,05234141 ! regulation of translational initiation GO:0006446 64 45 0,000 0,04535497 0,05231517 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,04535497 0,05228894 ! cell recognition GO:0008037 58 45 0,000 0,04535497 0,05226275 ! cell maturation GO:0048469 60 45 0,000 0,04535497 0,05223657 ! protein amino acid autophosphorylation GO:0046777 80 45 0,000 0,04535497 0,05221043 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,04634044 0,05331817 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,04634044 0,05329151 ! cell redox homeostasis GO:0045454 63 46 0,000 0,04634044 0,05326488 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,04634044 0,05323827 ! regulation of ossification GO:0030278 71 46 0,000 0,04634044 0,05321169 ! histone modification GO:0016570 68 46 0,000 0,04634044 0,05318514 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,04634044 0,05315861 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,04732495 0,05426091 ! viral infectious cycle GO:0019058 71 47 0,000 0,04732495 0,05423387 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,04732495 0,05420686 ! endocrine system development GO:0035270 83 47 0,000 0,04732495 0,05417988 ! covalent chromatin modification GO:0016569 75 47 0,000 0,04732495 0,05415293 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,04732495 0,054126 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,04732495 0,0540991 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,04732495 0,05407222 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,04732495 0,05404537 ! regulation of leukocyte proliferation GO:0070663 71 47 0,000 0,04732495 0,05401855 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,04732495 0,05399176 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,04732495 0,05396499 ! chloride transport GO:0006821 67 48 0,000 0,0483085 0,05505924 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,0483085 0,05503197 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 0,000 0,0483085 0,05500472 ! response to temperature stimulus GO:0009266 62 48 0,000 0,0483085 0,05497751 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,0483085 0,05495032 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,0483085 0,05492316 ! gastrulation GO:0007369 73 48 0,000 0,0483085 0,05489602 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,0483085 0,05486891 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,0483085 0,05484183 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,0483085 0,05481477 ! regulation of endocytosis GO:0030100 63 48 0,000 0,0483085 0,05478774 ! nuclear export GO:0051168 69 48 0,000 0,0483085 0,05476074 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,0483085 0,05473377 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,04929109 0,05581955 ! sensory perception of smell GO:0007608 61 49 0,000 0,04929109 0,05579208 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,04929109 0,05576463 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,04929109 0,05573722 ! RNA elongation GO:0006354 62 49 0,000 0,04929109 0,05570983 ! regulation of intracellular transport GO:0032386 78 49 0,000 0,04929109 0,05568246 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,04929109 0,05565513 ! germ cell development GO:0007281 68 49 0,000 0,04929109 0,05562782 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,04929109 0,05560054 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,04929109 0,05557328 ! maintenance of location GO:0051235 84 49 0,000 0,04929109 0,05554605 ! regulation of actin filament length GO:0030832 72 50 0,000 0,05027272 0,05662451 ! ear development GO:0043583 72 50 0,000 0,05027272 0,05659679 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,05027272 0,0565691 ! membrane fusion GO:0006944 80 50 0,000 0,05027272 0,05654144 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,05027272 0,05651381 ! lipid modification GO:0030258 73 50 0,000 0,05027272 0,0564862 ! positive regulation of growth GO:0045927 67 50 0,000 0,05027272 0,05645862 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,05027272 0,05643106 ! proton transport GO:0015992 75 50 0,000 0,05027272 0,05640353 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,05027272 0,05637603 ! positive regulation of secretion GO:0051047 71 51 0,000 0,05125339 0,05744776 ! hydrogen transport GO:0006818 77 51 0,000 0,05125339 0,05741977 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,05125339 0,05739182 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 0,000 0,05125339 0,05736389 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,05125339 0,05733599 ! adult behavior GO:0030534 80 51 0,000 0,05125339 0,05730812 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,05125339 0,05728027 ! transition metal ion transport GO:0000041 74 52 0,000 0,05223311 0,05834684 ! regulation of cellular component size GO:0032535 74 52 0,000 0,05223311 0,05831852 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,05223311 0,05829022 ! aging GO:0007568 79 52 0,000 0,05223311 0,05826195 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,05223311 0,05823371 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,05321187 0,05929617 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,05321187 0,05926745 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,05321187 0,05923877 ! kidney development GO:0001822 90 53 0,000 0,05321187 0,05921011 ! single fertilization GO:0007338 59 53 0,000 0,05321187 0,05918148 ! cell projection assembly GO:0030031 76 53 0,000 0,05321187 0,05915287 ! amino acid transport GO:0006865 84 54 0,000 0,05418967 0,06021075 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,05418967 0,06018167 ! glucose catabolic process GO:0006007 66 54 0,000 0,05418967 0,06015263 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,05418967 0,06012361 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,05418967 0,06009462 ! DNA catabolic process GO:0006308 67 54 0,000 0,05418967 0,06006566 ! detection of external stimulus GO:0009581 66 54 0,000 0,05418967 0,06003673 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,05418967 0,06000782 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,05418967 0,05997894 ! exocytosis GO:0006887 74 55 0,000 0,05516653 0,06103079 ! mesoderm development GO:0007498 76 55 0,000 0,05516653 0,06100145 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,05516653 0,06097213 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,05516653 0,06094285 ! DNA damage response, signal transduction GO:0042770 96 56 0,000 0,05614242 0,06199116 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,05614242 0,06196141 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,05614242 0,06193169 ! negative regulation of protein kinase activity GO:0006469 99 57 0,000 0,05711737 0,06297697 ! carbohydrate transport GO:0008643 74 57 0,000 0,05711737 0,06294679 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,05711737 0,06291665 GO:0048609|reproductive process in a multicellular organism, ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,05711737 0,06288653 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,05711737 0,06285644 ! camera-type eye development GO:0043010 88 57 0,000 0,05711737 0,06282638 ! secondary metabolic process GO:0019748 84 57 0,000 0,05711737 0,06279635 ! response to peptide hormone stimulus GO:0043434 84 57 0,000 0,05711737 0,06276634 ! developmental maturation GO:0021700 75 57 0,000 0,05711737 0,06273637 ! gonad development GO:0008406 79 57 0,000 0,05711737 0,06270642 ! negative regulation of kinase activity GO:0033673 100 58 0,000 0,05809137 0,0637453 ! viral reproductive process GO:0022415 87 58 0,000 0,05809137 0,0637149 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,05809137 0,06368453 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,05809137 0,06365419 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,05809137 0,06362388 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,05906441 0,06465881 ! activation of MAPK activity GO:0000187 84 59 0,000 0,05906441 0,06462805 ! actin filament organization GO:0007015 95 59 0,000 0,05906441 0,06459732 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,05906441 0,06456661 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,05906441 0,06453594 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,06003651 0,06556694 ! phosphoinositide metabolic process GO:0030384 87 60 0,000 0,06003651 0,06553582 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,06003651 0,06550473 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,06003651 0,06547367 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,06003651 0,06544264 ! regulation of heart contraction GO:0008016 91 60 0,000 0,06003651 0,06541164 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,06003651 0,06538067 ! fertilization GO:0009566 68 60 0,000 0,06003651 0,06534973 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,06100766 0,06637541 ! cell-matrix adhesion GO:0007160 114 61 0,000 0,06100766 0,06634403 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,06100766 0,06631267 ! urogenital system development GO:0001655 101 61 0,000 0,06100766 0,06628135 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,06100766 0,06625006 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,06100766 0,06621879 ! extracellular matrix organization GO:0030198 103 61 0,000 0,06100766 0,06618756 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,06100766 0,06615635 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! negative regulation of transferase activity GO:0051348 105 61 0,000 0,06100766 0,06612517 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 0,000 0,06100766 0,06609403 ! amine catabolic process GO:0009310 90 62 0,000 0,06197786 0,0671135 ! neurotransmitter transport GO:0006836 81 62 0,000 0,06197786 0,06708192 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,06197786 0,06705037 ! negative regulation of cell growth GO:0030308 106 62 0,000 0,06197786 0,06701884 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,06197786 0,06698735 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 0,000 0,06197786 0,06695588 ! regulation of transcription factor activity GO:0051090 97 63 0,000 0,06294711 0,06797106 GO:0090046|regulation of transcription regulator activity, ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,06294711 0,06793917 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 0,000 0,06294711 0,0679073 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 0,000 0,06294711 0,06787546 ! viral reproduction GO:0016032 92 63 0,000 0,06294711 0,06784366 ! regulation of lipase activity GO:0060191 109 63 0,000 0,06294711 0,06781188 ! cell cycle checkpoint GO:0000075 108 64 0,000 0,06391542 0,06882279 ! negative regulation of cell size GO:0045792 108 64 0,000 0,06391542 0,06879058 ! appendage morphogenesis GO:0035107 93 64 0,000 0,06391542 0,0687584 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,06391542 0,06872626 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,06391542 0,06869414 ! hexose catabolic process GO:0019320 82 64 0,000 0,06391542 0,06866206 ! reproductive structure development GO:0048608 90 65 0,000 0,06488278 0,06966872 ! regulation of caspase activity GO:0043281 97 65 0,000 0,06488278 0,06963621 ! appendage development GO:0048736 94 65 0,000 0,06488278 0,06960373 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 0,000 0,06488278 0,06957128 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 0,000 0,06488278 0,06953886 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 0,000 0,06488278 0,06950648 ! defense response to bacterium GO:0042742 73 65 0,000 0,06488278 0,06947412 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,06488278 0,06944179 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,06488278 0,06940949 ! activation of immune response GO:0002253 83 65 0,000 0,06488278 0,06937722 ! protein oligomerization GO:0051259 100 65 0,000 0,06488278 0,06934498 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,0658492 0,07034518 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,0658492 0,07031252 ! antigen processing and presentation GO:0019882 96 66 0,000 0,0658492 0,07027989 ! axon guidance GO:0007411 99 66 0,000 0,0658492 0,07024729 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,0658492 0,07021473 ! regulation of immune effector process GO:0002697 101 66 0,000 0,0658492 0,07018219 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,06681468 0,07117821 ! regulation of endopeptidase activity GO:0052548 99 67 0,000 0,06681468 0,07114526 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,06681468 0,07111234 ! acute inflammatory response GO:0002526 92 68 0,000 0,06777921 0,07210554 ! learning or memory GO:0007611 123 68 0,000 0,06777921 0,07207221 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,06777921 0,0720389 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,06777921 0,07200563 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,06777921 0,07197238 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,06777921 0,07193917 ! rhythmic process GO:0048511 105 68 0,000 0,06777921 0,07190599 ! inorganic anion transport GO:0015698 93 68 0,000 0,06777921 0,07187284 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,0687428 0,07286103 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,0687428 0,07282747 ! response to drug GO:0042493 108 69 0,000 0,0687428 0,07279394 ! positive regulation of ligase activity GO:0051351 99 69 0,000 0,0687428 0,07276044 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,06970545 0,07374542 ! humoral immune response GO:0006959 86 70 0,000 0,06970545 0,07371151 ! eye development GO:0001654 111 70 0,000 0,06970545 0,07367764 ! amine transport GO:0015837 101 70 0,000 0,06970545 0,07364379 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,06970545 0,07360998 ! muscle cell differentiation GO:0042692 104 71 0,000 0,07066716 0,07459131 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,07066716 0,0745571 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 0,000 0,07066716 0,07452291 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,07066716 0,07448876 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,07066716 0,07445464 ! regulation of peptidase activity GO:0052547 106 72 0,000 0,07162793 0,07543235 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,07162793 0,07539782 ! negative regulation of transport GO:0051051 116 73 0,000 0,07258777 0,07637322 ! regulation of blood pressure GO:0008217 107 73 0,000 0,07258777 0,0763383 ! tube morphogenesis GO:0035239 118 73 0,000 0,07258777 0,07630341 ! mitochondrion organization GO:0007005 104 73 0,000 0,07258777 0,07626855 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,07258777 0,07623373 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,07258777 0,07619893 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,07354666 0,07717031 ! digestion GO:0007586 97 74 0,000 0,07354666 0,07713512 ! protein import into nucleus GO:0006606 118 74 0,000 0,07354666 0,07709997 ! cellular response to hormone stimulus GO:0032870 109 74 0,000 0,07354666 0,07706484 ! positive regulation of lymphocyte activation GO:0051251 108 74 0,000 0,07354666 0,07702975 ! blood coagulation GO:0007596 116 75 0,000 0,07450462 0,07799756 GO:0050817|coagulation, ! response to nutrient GO:0007584 104 75 0,000 0,07450462 0,07796207 ! regulation of ligase activity GO:0051340 114 75 0,000 0,07450462 0,07792662 ! nuclear import GO:0051170 121 75 0,000 0,07450462 0,0778912 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,07450462 0,07785581 ! amine biosynthetic process GO:0009309 97 76 0,000 0,07546165 0,07882007 ! tRNA metabolic process GO:0006399 95 76 0,000 0,07546165 0,07878429 ! regulation of protein transport GO:0051223 114 76 0,000 0,07546165 0,07874854 GO:0070201|regulation of establishment of protein localization, ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,07641774 0,07971011 ! regulation of DNA binding GO:0051101 119 77 0,000 0,07641774 0,07967398 ! gland development GO:0048732 148 77 0,000 0,07641774 0,07963788 ! sex differentiation GO:0007548 105 77 0,000 0,07641774 0,07960181 ! protein ubiquitination GO:0016567 125 77 0,000 0,07641774 0,07956577 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,07641774 0,07952977 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,07641774 0,0794938 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,07641774 0,07945786 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,07737289 0,08041466 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,07737289 0,08037834 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,07832711 0,08133289 ! cellular respiration GO:0045333 107 79 0,000 0,07832711 0,08129619 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,07832711 0,08125952 ! T cell activation GO:0042110 134 79 0,000 0,07832711 0,08122289 ! regulation of lyase activity GO:0051339 133 79 0,000 0,07832711 0,08118628 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,07832711 0,08114971 ! chromatin assembly GO:0031497 102 80 0,000 0,0792804 0,08210037 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,0792804 0,08206342 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 0,000 0,0792804 0,08202651 GO:0010498|proteasomal protein catabolic process, ! protein localization in nucleus GO:0034504 133 80 0,000 0,0792804 0,08198963 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,0792804 0,08195278 ! forebrain development GO:0030900 131 80 0,000 0,0792804 0,08191596 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,08023276 0,08286275 ! hemostasis GO:0007599 125 81 0,000 0,08023276 0,08282556 ! mRNA transport GO:0051028 121 81 0,000 0,08023276 0,08278841 ! regulation of neurological system process GO:0031644 122 81 0,000 0,08023276 0,08275128 ! vitamin metabolic process GO:0006766 103 81 0,000 0,08023276 0,08271419 ! positive regulation of cell activation GO:0050867 120 81 0,000 0,08023276 0,08267713 GO:0002696|positive regulation of leukocyte activation, ! ossification GO:0001503 134 82 0,000 0,08118419 0,08362008 GO:0060348|bone development, ! detection of stimulus GO:0051606 108 82 0,000 0,08118419 0,08358265 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,08213469 0,0845234 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,08213469 0,08448559 ! regulation of cell adhesion GO:0030155 159 83 0,000 0,08213469 0,08444783 ! regulation of defense response GO:0031347 117 84 0,000 0,08308426 0,08538597 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,08308426 0,08534783 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,0840329 0,08628379 ! rRNA metabolic process GO:0016072 107 85 0,000 0,0840329 0,08624528 GO:0006364|rRNA processing, ! positive regulation of MAP kinase activity GO:0043406 121 85 0,000 0,0840329 0,08620681 ! transcription initiation GO:0006352 118 85 0,000 0,0840329 0,08616838 ! anterior/posterior pattern formation GO:0009952 124 85 0,000 0,0840329 0,08612998 ! regulation of protein localization GO:0032880 132 85 0,000 0,0840329 0,08609162 ! regulation of membrane potential GO:0042391 128 85 0,000 0,0840329 0,08605329 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,08498062 0,08698506 ! cell cycle arrest GO:0007050 150 86 0,000 0,08498062 0,08694636 ! nucleosome organization GO:0034728 114 87 0,000 0,08592741 0,08787596 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,08592741 0,08783691 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,08592741 0,08779789 ! skeletal muscle tissue development GO:0007519 123 87 0,000 0,08592741 0,0877589 GO:0060538|skeletal muscle organ development, ! female pregnancy GO:0007565 130 87 0,000 0,08592741 0,08771995 ! Wnt receptor signaling pathway GO:0016055 130 87 0,000 0,08592741 0,08768103 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,08687327 0,08860689 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,08687327 0,08856761 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,08687327 0,08852837 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 0,000 0,08687327 0,08848916 ! regulation of neurogenesis GO:0050767 153 89 0,000 0,08781821 0,08941208 ! reproductive developmental process GO:0003006 127 89 0,000 0,08781821 0,08937252 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,08781821 0,08933299 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,08781821 0,0892935 ! regulation of T cell activation GO:0050863 128 89 0,000 0,08781821 0,08925404 ! leukocyte differentiation GO:0002521 143 90 0,000 0,08876223 0,09017364 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,08876223 0,09013383 ! hormone metabolic process GO:0042445 121 90 0,000 0,08876223 0,09009405 ! RNA localization GO:0006403 135 91 0,000 0,08970532 0,09101113 ! ATP metabolic process GO:0046034 137 91 0,000 0,08970532 0,09097101 ! response to virus GO:0009615 122 91 0,000 0,08970532 0,09093091 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,09064749 0,09184548 ! glycerophospholipid metabolic process GO:0006650 130 92 0,000 0,09064749 0,09180504 ! cell fate commitment GO:0045165 141 92 0,000 0,09064749 0,09176463 ! positive regulation of immune response GO:0050778 121 92 0,000 0,09064749 0,09172426 ! DNA recombination GO:0006310 146 92 0,000 0,09064749 0,09168392 ! sulfur metabolic process GO:0006790 118 92 0,000 0,09064749 0,09164362 ! regulation of cytoskeleton organization GO:0051493 154 93 0,000 0,09158874 0,09255453 ! peptidyl-amino acid modification GO:0018193 147 93 0,000 0,09158874 0,09251388 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,09158874 0,09247327 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,09158874 0,09243269 ! electron transport chain GO:0022900 123 94 0,000 0,09252907 0,09334073 ! regulation of binding GO:0051098 151 95 0,000 0,09346849 0,09424705 ! carboxylic acid transport GO:0046942 147 95 0,000 0,09346849 0,09420575 GO:0015849|organic acid transport, ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,09440698 0,09510996 ! regulation of cellular component biogenesis GO:0044087 158 96 0,000 0,09440698 0,09506832 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,09440698 0,09502672 ! protein maturation GO:0051604 129 96 0,000 0,09440698 0,09498515 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,09534455 0,09588652 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,09534455 0,09584461 ! calcium ion transport GO:0006816 167 99 0,000 0,09721695 0,09768414 ! extracellular structure organization GO:0043062 156 99 0,000 0,09721695 0,09764148 ! protein import GO:0017038 156 99 0,000 0,09721695 0,09759886 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 0,000 0,09721695 0,09755628 ! regulation of translation GO:0006417 151 100 0,000 0,09815178 0,09845141 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,09815178 0,0984085 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,09815178 0,09836562 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,09815178 0,09832278 ! divalent metal ion transport GO:0070838 171 100 0,000 0,09815178 0,09827997 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,09815178 0,0982372 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,09815178 0,09819447 ! protein localization in organelle GO:0033365 161 100 0,000 0,09815178 0,09815178