pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-b1/out-0.05-06-0.01-300-run-b1//th1-pval-1e-01-08-th2-pval-1e-02-02-th3-pval-1e-01-01-run-b1/go_data/7057-8-real-Wang-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 2,000 1,727E-08 3,972E-05 ! regulation of focal adhesion formation GO:0051893 17 7 2,000 6,034E-08 6,939E-05 ! positive regulation of endothelial cell migration GO:0010595 18 8 2,000 9,647E-08 7,396E-05 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 2,000 3,778E-07 2,172E-04 ! regulation of endothelial cell migration GO:0010594 40 19 2,000 1,654E-06 7,61E-04 ! positive regulation of locomotion GO:0040017 35 20 2,000 1,945E-06 7,455E-04 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! regulation of chemotaxis GO:0050920 36 21 2,000 2,267E-06 7,449E-04 ! regulation of cell-matrix adhesion GO:0001952 51 22 2,000 2,623E-06 7,541E-04 GO:0010810|regulation of cell-substrate adhesion, ! regulation of behavior GO:0050795 38 22 2,000 2,623E-06 6,703E-04 ! regulation of blood coagulation GO:0030193 34 22 2,000 2,623E-06 6,032E-04 ! regulation of endothelial cell proliferation GO:0001936 46 24 2,000 3,441E-06 7,196E-04 ! positive regulation of MAP kinase activity GO:0043406 121 85 3,000 3,561E-06 6,825E-04 ! negative regulation of protein modification process GO:0031400 50 26 2,000 4,414E-06 7,809E-04 ! regulation of coagulation GO:0050818 39 26 2,000 4,414E-06 7,251E-04 ! Ras protein signal transduction GO:0007265 162 100 3,000 6,812E-06 1,044E-03 ! negative regulation of protein ubiquitination GO:0031397 7 5 1,000 1,508E-05 2,168E-03 ! apoptotic cell clearance GO:0043277 13 5 1,000 1,508E-05 2,041E-03 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 1,000 1,508E-05 1,927E-03 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 1,000 1,508E-05 1,826E-03 ! positive regulation of Rho GTPase activity GO:0032321 9 5 1,000 1,508E-05 1,735E-03 ! positive regulation of blood coagulation GO:0030194 10 5 1,000 1,508E-05 1,652E-03 ! response to calcium ion GO:0051592 58 40 2,000 1,658E-05 1,734E-03 ! positive regulation of response to external stimulus GO:0032103 65 40 2,000 1,658E-05 1,658E-03 ! negative regulation of cell migration GO:0030336 92 44 2,000 2,216E-05 2,123E-03 ! negative regulation of focal adhesion formation GO:0051895 16 6 1,000 2,261E-05 2,08E-03 ! regulation of macrophage activation GO:0043030 11 6 1,000 2,261E-05 2E-03 ! regulation of Rac protein signal transduction GO:0035020 8 6 1,000 2,261E-05 1,926E-03 ! positive regulation of coagulation GO:0050820 11 6 1,000 2,261E-05 1,857E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 3,163E-05 2,508E-03 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 1,000 3,163E-05 2,425E-03 ! regulation of smooth muscle cell migration GO:0014910 19 7 1,000 3,163E-05 2,346E-03 ! regulation of lipid transport GO:0032368 13 7 1,000 3,163E-05 2,273E-03 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 1,000 3,163E-05 2,204E-03 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 2,000 3,464E-05 2,343E-03 ! positive regulation of cell migration GO:0030335 92 51 2,000 3,464E-05 2,276E-03 ! negative regulation of cell motion GO:0051271 104 51 2,000 3,464E-05 2,213E-03 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 1,000 4,214E-05 2,619E-03 GO:0046579|positive regulation of Ras protein signal transduction, ! positive regulation of Ras GTPase activity GO:0032320 20 8 1,000 4,214E-05 2,55E-03 ! regulation of fibrinolysis GO:0051917 13 8 1,000 4,214E-05 2,485E-03 ! negative regulation of organic acid transport GO:0032891 12 8 1,000 4,214E-05 2,423E-03 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 1,000 4,214E-05 2,364E-03 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 1,000 4,214E-05 2,307E-03 ! positive regulation of cell motion GO:0051272 99 56 2,000 4,592E-05 2,456E-03 ! positive regulation of GTPase activity GO:0043547 21 9 1,000 5,413E-05 2,83E-03 ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 1,000 5,413E-05 2,767E-03 ! regulation of stress fiber formation GO:0051492 20 9 1,000 5,413E-05 2,707E-03 ! substrate-bound cell migration GO:0006929 10 9 1,000 5,413E-05 2,649E-03 ! regulation of phosphatase activity GO:0010921 21 10 1,000 6,762E-05 3,24E-03 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 1,000 6,762E-05 3,174E-03 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 1,000 6,762E-05 3,11E-03 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 1,000 6,762E-05 3,049E-03 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 1,000 6,762E-05 2,991E-03 ! phagocytosis, engulfment GO:0006911 20 10 1,000 6,762E-05 2,934E-03 ! positive regulation of leukocyte migration GO:0002687 23 10 1,000 6,762E-05 2,88E-03 ! regulation of actin filament bundle formation GO:0032231 21 10 1,000 6,762E-05 2,828E-03 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 1,000 8,258E-05 3,392E-03 ! regulation of Rho GTPase activity GO:0032319 18 11 1,000 8,258E-05 3,332E-03 ! regulation of leukocyte migration GO:0002685 24 11 1,000 8,258E-05 3,275E-03 ! regulation of organic acid transport GO:0032890 17 11 1,000 8,258E-05 3,219E-03 ! response to metal ion GO:0010038 103 70 2,000 8,965E-05 3,437E-03 ! positive regulation of phosphorylation GO:0042327 102 70 2,000 8,965E-05 3,38E-03 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 2,000 9,752E-05 3,618E-03 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 132 72 2,000 9,752E-05 3,56E-03 ! negative regulation of endothelial cell migration GO:0010596 21 12 1,000 9,902E-05 3,558E-03 ! regulation of interleukin-12 production GO:0032655 16 12 1,000 9,902E-05 3,504E-03 ! response to steroid hormone stimulus GO:0048545 114 73 2,000 1,016E-04 3,541E-03 ! response to oxygen levels GO:0070482 137 74 2,000 1,058E-04 3,633E-03 ! response to inorganic substance GO:0010035 115 75 2,000 1,101E-04 3,725E-03 ! response to hexose stimulus GO:0009746 19 13 1,000 1,169E-04 3,898E-03 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 1,000 1,169E-04 3,842E-03 ! G1 phase of mitotic cell cycle GO:0000080 23 14 1,000 1,363E-04 4,416E-03 ! regulation of lipid biosynthetic process GO:0046890 16 14 1,000 1,363E-04 4,355E-03 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 1,000 1,363E-04 4,295E-03 ! negative regulation of blood coagulation GO:0030195 19 14 1,000 1,363E-04 4,237E-03 ! regulation of cell adhesion GO:0030155 159 83 2,000 1,489E-04 4,566E-03 ! regulation of protein ubiquitination GO:0031396 19 15 1,000 1,572E-04 4,756E-03 ! negative regulation of multicellular organismal process GO:0051241 133 85 2,000 1,598E-04 4,773E-03 ! interphase of mitotic cell cycle GO:0051329 156 86 2,000 1,654E-04 4,878E-03 ! interphase GO:0051325 159 88 2,000 1,771E-04 5,156E-03 ! cellular response to unfolded protein GO:0034620 19 16 1,000 1,795E-04 5,16E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! regulation of dephosphorylation GO:0035303 33 16 1,000 1,795E-04 5,096E-03 ! G1 phase GO:0051318 27 16 1,000 1,795E-04 5,034E-03 ! negative regulation of translation GO:0017148 22 16 1,000 1,795E-04 4,974E-03 ! negative regulation of coagulation GO:0050819 23 17 1,000 2,033E-04 5,565E-03 ! positive regulation of DNA replication GO:0045740 29 18 1,000 2,285E-04 6,183E-03 ! positive regulation of translation GO:0045727 28 18 1,000 2,285E-04 6,111E-03 ! positive regulation of angiogenesis GO:0045766 35 18 1,000 2,285E-04 6,041E-03 ! response to carbohydrate stimulus GO:0009743 24 18 1,000 2,285E-04 5,972E-03 ! peptide cross-linking GO:0018149 31 18 1,000 2,285E-04 5,905E-03 ! visual learning GO:0008542 35 18 1,000 2,285E-04 5,839E-03 ! regulation of response to external stimulus GO:0032101 139 96 2,000 2,291E-04 5,79E-03 ! regulation of cellular component biogenesis GO:0044087 158 96 2,000 2,291E-04 5,727E-03 ! response to light stimulus GO:0009416 153 96 2,000 2,291E-04 5,666E-03 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 2,000 2,509E-04 6,139E-03 ! positive regulation of fibroblast proliferation GO:0048146 27 19 1,000 2,552E-04 6,178E-03 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 1,000 2,552E-04 6,114E-03 ! negative regulation of angiogenesis GO:0016525 36 19 1,000 2,552E-04 6,051E-03 ! regulation of translation GO:0006417 151 100 2,000 2,584E-04 6,065E-03 ! visual behavior GO:0007632 39 21 1,000 3,129E-04 7,269E-03 ! cell aging GO:0007569 32 21 1,000 3,129E-04 7,197E-03 ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 3,129E-04 7,126E-03 ! response to glucocorticoid stimulus GO:0051384 33 21 1,000 3,129E-04 7,056E-03 ! negative regulation of cytokine production GO:0001818 31 21 1,000 3,129E-04 6,987E-03 ! regulation of fibroblast proliferation GO:0048145 35 22 1,000 3,439E-04 7,606E-03 ! positive regulation of cell adhesion GO:0045785 37 23 1,000 3,764E-04 8,245E-03 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 3,764E-04 8,167E-03 ! response to corticosteroid stimulus GO:0031960 36 23 1,000 3,764E-04 8,091E-03 ! fat cell differentiation GO:0045444 37 24 1,000 4,103E-04 8,738E-03 ! negative regulation of neuron apoptosis GO:0043524 42 27 1,000 5,206E-04 0,01098534 ! negative regulation of cell activation GO:0050866 44 30 1,000 6,437E-04 0,01345974 ! response to heat GO:0009408 41 30 1,000 6,437E-04 0,01333848 ! regulation of synaptic plasticity GO:0048167 52 32 1,000 7,329E-04 0,01505018 ! RNA export from nucleus GO:0006405 44 33 1,000 7,796E-04 0,01586729 ! positive regulation of DNA metabolic process GO:0051054 54 33 1,000 7,796E-04 0,0157281 ! negative regulation of cell adhesion GO:0007162 67 33 1,000 7,796E-04 0,01559134 ! keratinocyte differentiation GO:0030216 47 35 1,000 8,772E-04 0,0173918 ! learning GO:0007612 67 37 1,000 9,803E-04 0,01927136 ! amino acid activation GO:0043038 52 37 1,000 9,803E-04 0,01910804 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 1,000 1,034E-03 0,01998488 ! striated muscle cell differentiation GO:0051146 54 38 1,000 1,034E-03 0,01981834 ! phagocytosis GO:0006909 60 38 1,000 1,034E-03 0,01965455 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 1,000 1,089E-03 0,02053151 ! cell growth GO:0016049 61 39 1,000 1,089E-03 0,02036458 ! epidermal cell differentiation GO:0009913 53 40 1,000 1,146E-03 0,02124734 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 1,000 1,323E-03 0,02434542 ! response to insulin stimulus GO:0032868 63 43 1,000 1,323E-03 0,0241522 ! positive regulation of cell cycle GO:0045787 77 45 1,000 1,448E-03 0,02623069 ! response to UV GO:0009411 75 46 1,000 1,513E-03 0,02718805 ! negative regulation of immune system process GO:0002683 73 47 1,000 1,579E-03 0,02815483 ! regulation of neuron apoptosis GO:0043523 77 47 1,000 1,579E-03 0,02793826 ! response to temperature stimulus GO:0009266 62 48 1,000 1,647E-03 0,02890841 ! regulation of DNA replication GO:0006275 75 48 1,000 1,647E-03 0,02868941 ! nuclear export GO:0051168 69 48 1,000 1,647E-03 0,0284737 ! positive regulation of cytokine production GO:0001819 73 48 1,000 1,647E-03 0,02826121 ! regulation of angiogenesis GO:0045765 94 49 1,000 1,715E-03 0,02922331 ! aging GO:0007568 79 52 1,000 1,93E-03 0,03263388 ! cell projection assembly GO:0030031 76 53 1,000 2,004E-03 0,03364049 ! regulation of mitosis GO:0007088 84 54 1,000 2,079E-03 0,03465482 GO:0051783|regulation of nuclear division, ! regulation of lipid metabolic process GO:0019216 84 56 1,000 2,234E-03 0,03696989 ! response to peptide hormone stimulus GO:0043434 84 57 1,000 2,314E-03 0,03801164 ! activation of MAPK activity GO:0000187 84 59 1,000 2,477E-03 0,04040004 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 1,000 2,645E-03 0,04284034 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 1,000 2,731E-03 0,04392536 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 1,000 2,818E-03 0,04501624 ! regulation of actin cytoskeleton organization GO:0032956 97 64 1,000 2,907E-03 0,04611282 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 1,000 2,907E-03 0,04579698 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 1,000 2,997E-03 0,04689374 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 1,000 2,997E-03 0,04657689 ! regulation of actin filament-based process GO:0032970 99 66 1,000 3,088E-03 0,04767378 ! regulation of Rho protein signal transduction GO:0035023 111 66 1,000 3,088E-03 0,04735596 ! learning or memory GO:0007611 123 68 1,000 3,275E-03 0,04988326 ! regulation of Ras GTPase activity GO:0032318 110 68 1,000 3,275E-03 0,04955509 ! positive regulation of ligase activity GO:0051351 99 69 1,000 3,37E-03 0,05066225 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 1,000 3,467E-03 0,05177428 ! muscle cell differentiation GO:0042692 104 71 1,000 3,564E-03 0,05289105 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 1,000 3,564E-03 0,052552 ! regulation of synaptic transmission GO:0050804 109 72 1,000 3,663E-03 0,05366838 ! negative regulation of transport GO:0051051 116 73 1,000 3,764E-03 0,05478926 ! regulation of ligase activity GO:0051340 114 75 1,000 3,968E-03 0,05740276 ! tRNA metabolic process GO:0006399 95 76 1,000 4,072E-03 0,05854121 ! response to unfolded protein GO:0006986 99 76 1,000 4,072E-03 0,0581776 ! regulation of transmission of nerve impulse GO:0051969 116 77 1,000 4,178E-03 0,0593152 ! positive regulation of protein modification process GO:0031401 107 78 1,000 4,285E-03 0,06045669 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 1,000 4,502E-03 0,06313349 GO:0010498|proteasomal protein catabolic process, ! regulation of GTPase activity GO:0043087 129 80 1,000 4,502E-03 0,06275087 ! regulation of cell cycle process GO:0010564 122 81 1,000 4,612E-03 0,06390333 ! response to protein stimulus GO:0051789 111 81 1,000 4,612E-03 0,06352068 ! regulation of neurological system process GO:0031644 122 81 1,000 4,612E-03 0,06314258 ! positive regulation of cell activation GO:0050867 120 81 1,000 4,612E-03 0,06276895 GO:0002696|positive regulation of leukocyte activation, ! regulation of DNA metabolic process GO:0051052 135 85 1,000 5,066E-03 0,06854662 ! cell cycle arrest GO:0007050 150 86 1,000 5,183E-03 0,0697153 ! establishment of RNA localization GO:0051236 128 88 1,000 5,42E-03 0,07248039 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! RNA localization GO:0006403 135 91 1,000 5,785E-03 0,07691221 ! regulation of cytoskeleton organization GO:0051493 154 93 1,000 6,034E-03 0,0797663 ! response to oxidative stress GO:0006979 141 94 1,000 6,161E-03 0,08097313 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 6,277E-03 0,0820301 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 6,277E-03 0,08156665 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 6,277E-03 0,08110841 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 6,277E-03 0,08065529 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 6,277E-03 0,08020721 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 6,277E-03 0,07976407 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 6,277E-03 0,07932581 ! sleep GO:0030431 11 5 0,000 6,277E-03 0,07889234 ! negative regulation of bone resorption GO:0045779 10 5 0,000 6,277E-03 0,07846357 ! nucleotide-sugar transport GO:0015780 8 5 0,000 6,277E-03 0,07803945 ! regulation of interferon-beta production GO:0032648 5 5 0,000 6,277E-03 0,07761988 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 6,277E-03 0,0772048 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 6,277E-03 0,07679414 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 6,277E-03 0,07638782 ! tongue development GO:0043586 6 5 0,000 6,277E-03 0,07598578 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 6,277E-03 0,07558795 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 6,277E-03 0,07519426 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 6,277E-03 0,07480465 ! cobalt ion transport GO:0006824 9 5 0,000 6,277E-03 0,07441906 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 6,277E-03 0,07403742 ! SMAD protein complex assembly GO:0007183 9 5 0,000 6,277E-03 0,07365968 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 6,277E-03 0,07328577 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 6,277E-03 0,07291564 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 6,277E-03 0,07254923 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 6,277E-03 0,07218649 ! embryonic camera-type eye development GO:0031076 8 5 0,000 6,277E-03 0,07182735 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 6,277E-03 0,07147177 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 6,277E-03 0,07111969 ! adaptation of signaling pathway GO:0022401 7 5 0,000 6,277E-03 0,07077107 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 6,277E-03 0,07042584 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 6,277E-03 0,07008397 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 6,277E-03 0,0697454 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 6,277E-03 0,06941008 ! positive regulation of histone modification GO:0031058 5 5 0,000 6,277E-03 0,06907798 ! malate metabolic process GO:0006108 7 5 0,000 6,277E-03 0,06874904 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 6,277E-03 0,06842321 ! behavioral response to pain GO:0048266 7 5 0,000 6,277E-03 0,06810046 ! clathrin coat assembly GO:0048268 11 5 0,000 6,277E-03 0,06778074 ! phototransduction, visible light GO:0007603 6 5 0,000 6,277E-03 0,06746401 ! regulation of dopamine uptake GO:0051584 9 5 0,000 6,277E-03 0,06715022 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 6,277E-03 0,06683934 ! mating behavior GO:0007617 6 5 0,000 6,277E-03 0,06653132 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 6,277E-03 0,06622614 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 6,277E-03 0,06592373 ! rhythmic behavior GO:0007622 12 5 0,000 6,277E-03 0,06562408 ! copulation GO:0007620 7 5 0,000 6,277E-03 0,06532714 ! glial cell fate commitment GO:0021781 12 5 0,000 6,277E-03 0,06503287 ! protein maturation by protein folding GO:0022417 12 5 0,000 6,277E-03 0,06474124 ! embryonic hemopoiesis GO:0035162 10 5 0,000 6,277E-03 0,06445222 ! regulation of potassium ion transport GO:0043266 9 5 0,000 6,277E-03 0,06416577 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 6,277E-03 0,06388185 ! lipoprotein particle clearance GO:0034381 9 5 0,000 6,277E-03 0,06360043 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 6,277E-03 0,06332148 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 6,277E-03 0,06304497 ! response to protozoan GO:0001562 9 5 0,000 6,277E-03 0,06277086 ! positive regulation of glycolysis GO:0045821 11 5 0,000 6,277E-03 0,06249912 ! lymph vessel development GO:0001945 7 5 0,000 6,277E-03 0,06222973 ! endochondral ossification GO:0001958 12 5 0,000 6,277E-03 0,06196265 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 6,277E-03 0,06169785 ! parathyroid gland development GO:0060017 8 5 0,000 6,277E-03 0,06143531 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 6,277E-03 0,06117499 ! anagen GO:0042640 6 5 0,000 6,277E-03 0,06091687 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 6,277E-03 0,06066091 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 6,277E-03 0,0604071 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 6,277E-03 0,06015541 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 6,277E-03 0,0599058 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 6,277E-03 0,05965825 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 6,277E-03 0,05941275 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 6,277E-03 0,05916925 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 6,277E-03 0,05892774 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 6,277E-03 0,0586882 ! cardiac muscle fiber development GO:0048739 7 5 0,000 6,277E-03 0,0584506 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 6,277E-03 0,05821491 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 6,277E-03 0,05798111 ! neutrophil mediated immunity GO:0002446 6 5 0,000 6,277E-03 0,05774919 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 6,277E-03 0,05751911 ! ovulation GO:0030728 6 5 0,000 6,277E-03 0,05729086 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 6,277E-03 0,05706442 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 6,277E-03 0,05683975 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 6,277E-03 0,05661685 ! response to pH GO:0009268 9 5 0,000 6,277E-03 0,05639569 ! proline biosynthetic process GO:0006561 6 5 0,000 6,277E-03 0,05617625 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 6,277E-03 0,05595852 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 6,277E-03 0,05574246 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 6,277E-03 0,05552807 ! polyol catabolic process GO:0046174 7 5 0,000 6,277E-03 0,05531532 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 6,277E-03 0,05510419 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 6,277E-03 0,05489467 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 6,277E-03 0,05468673 ! sister chromatid cohesion GO:0007062 9 5 0,000 6,277E-03 0,05448037 ! nerve growth factor processing GO:0032455 7 5 0,000 6,277E-03 0,05427555 ! urea metabolic process GO:0019627 6 5 0,000 6,277E-03 0,05407228 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 6,277E-03 0,05387051 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 6,277E-03 0,05367025 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 6,277E-03 0,05347147 ! neutrophil activation GO:0042119 5 5 0,000 6,277E-03 0,05327416 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 6,277E-03 0,0530783 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 6,277E-03 0,05288387 ! response to food GO:0032094 5 5 0,000 6,277E-03 0,05269087 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 6,277E-03 0,05249926 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 6,277E-03 0,05230905 ! paraxial mesoderm development GO:0048339 9 5 0,000 6,277E-03 0,05212021 ! forebrain neuron development GO:0021884 7 5 0,000 6,277E-03 0,05193272 ! melanosome organization GO:0032438 7 5 0,000 6,277E-03 0,05174659 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 6,277E-03 0,05156178 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 6,277E-03 0,05137828 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 6,277E-03 0,05119609 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 6,277E-03 0,05101519 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 6,277E-03 0,05083555 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 6,277E-03 0,05065718 ! nucleoside transport GO:0015858 6 5 0,000 6,277E-03 0,05048006 ! nucleoside salvage GO:0043174 7 5 0,000 6,277E-03 0,05030417 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 6,277E-03 0,05012951 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 6,277E-03 0,04995605 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 6,277E-03 0,04978378 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 6,277E-03 0,04961271 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 6,277E-03 0,0494428 ! early endosome to late endosome transport GO:0045022 11 5 0,000 6,277E-03 0,04927405 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 6,277E-03 0,04910645 ! depyrimidination GO:0045008 8 5 0,000 6,277E-03 0,04893999 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 6,277E-03 0,04877465 ! 5S class rRNA transcription GO:0042791 8 5 0,000 6,277E-03 0,04861043 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 6,277E-03 0,04844731 ! regulation of centrosome cycle GO:0046605 7 5 0,000 6,277E-03 0,04828528 ! neuronal ion channel clustering GO:0045161 7 5 0,000 6,277E-03 0,04812433 ! sodium ion homeostasis GO:0055078 6 5 0,000 6,277E-03 0,04796444 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 6,277E-03 0,04780562 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 6,277E-03 0,04764785 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 6,277E-03 0,04749111 ! monocyte differentiation GO:0030224 8 5 0,000 6,277E-03 0,0473354 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 6,277E-03 0,04718071 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 6,277E-03 0,04702703 ! centrosome duplication GO:0051298 5 5 0,000 6,277E-03 0,04687434 ! response to UV-C GO:0010225 6 5 0,000 6,277E-03 0,04672265 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 6,277E-03 0,04657193 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 6,277E-03 0,04642218 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 6,277E-03 0,04627339 ! regulation of dendrite development GO:0050773 12 5 0,000 6,277E-03 0,04612555 ! peptidyl-arginine modification GO:0018195 7 5 0,000 6,277E-03 0,04597865 ! positive regulation of organ growth GO:0046622 6 5 0,000 6,277E-03 0,04583269 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 6,277E-03 0,04568765 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 6,277E-03 0,04554353 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 6,277E-03 0,04540031 ! regulation of dopamine secretion GO:0014059 12 5 0,000 6,277E-03 0,04525799 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 6,277E-03 0,04511655 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 6,277E-03 0,044976 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 6,277E-03 0,04483633 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 6,277E-03 0,04469752 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 6,277E-03 0,04455956 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 6,277E-03 0,04442245 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 6,277E-03 0,04428619 ! neural tube patterning GO:0021532 6 5 0,000 6,277E-03 0,04415076 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 6,277E-03 0,04401615 ! histone demethylation GO:0016577 9 5 0,000 6,277E-03 0,04388236 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 6,277E-03 0,04374939 ! regulation of sterol transport GO:0032371 7 5 0,000 6,277E-03 0,04361721 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 6,277E-03 0,04348584 ! enteric nervous system development GO:0048484 8 5 0,000 6,277E-03 0,04335525 ! establishment of planar polarity GO:0001736 6 5 0,000 6,277E-03 0,04322544 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 6,277E-03 0,04309641 ! muscle cell proliferation GO:0033002 8 5 0,000 6,277E-03 0,04296815 ! transcription termination GO:0006353 8 5 0,000 6,277E-03 0,04284065 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 6,277E-03 0,0427139 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 6,277E-03 0,0425879 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 6,277E-03 0,04246264 ! regulation of respiratory burst GO:0060263 8 5 0,000 6,277E-03 0,04233812 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 6,277E-03 0,04221432 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 6,277E-03 0,04209125 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 6,277E-03 0,04196889 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 6,277E-03 0,04184724 ! apical protein localization GO:0045176 6 5 0,000 6,277E-03 0,04172629 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 6,277E-03 0,04160604 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 6,277E-03 0,04148649 ! galactolipid metabolic process GO:0019374 7 5 0,000 6,277E-03 0,04136761 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 6,277E-03 0,04124942 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 6,277E-03 0,0411319 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 6,277E-03 0,04101505 ! triglyceride catabolic process GO:0019433 6 5 0,000 6,277E-03 0,04089886 ! glial cell migration GO:0008347 10 5 0,000 6,277E-03 0,04078333 ! determination of adult lifespan GO:0008340 8 5 0,000 6,277E-03 0,04066844 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 6,277E-03 0,04055421 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 6,277E-03 0,04044061 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 6,277E-03 0,04032765 ! somatic stem cell maintenance GO:0035019 13 5 0,000 6,277E-03 0,04021531 ! cerebellar cortex formation GO:0021697 6 5 0,000 6,277E-03 0,0401036 ! neural plate development GO:0001840 6 5 0,000 6,277E-03 0,03999251 ! regulation of sensory perception GO:0051931 6 5 0,000 6,277E-03 0,03988204 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 6,277E-03 0,03977217 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 6,277E-03 0,03966291 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 6,277E-03 0,03955424 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 6,277E-03 0,03944617 ! sensory cilium assembly GO:0035058 6 5 0,000 6,277E-03 0,03933869 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 6,277E-03 0,03923179 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 6,277E-03 0,03912547 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 6,277E-03 0,03901972 ! spindle assembly GO:0051225 5 5 0,000 6,277E-03 0,03891455 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 6,277E-03 0,03880994 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 6,277E-03 0,03870589 ! protein amino acid prenylation GO:0018346 9 5 0,000 6,277E-03 0,0386024 ! organ regeneration GO:0031100 7 5 0,000 6,277E-03 0,03849946 ! NAD biosynthetic process GO:0009435 7 5 0,000 6,277E-03 0,03839707 ! carnitine metabolic process GO:0009437 5 5 0,000 6,277E-03 0,03829522 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 6,277E-03 0,03819391 ! cellular anion homeostasis GO:0030002 6 5 0,000 6,277E-03 0,03809313 GO:0055081|anion homeostasis, ! angiogenesis GO:0001525 149 95 1,000 6,289E-03 0,03806328 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 1,000 6,418E-03 0,03874169 ! tRNA transcription GO:0009304 11 6 0,000 7,528E-03 0,04532554 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 7,528E-03 0,0452072 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 7,528E-03 0,04508947 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 7,528E-03 0,04497236 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 7,528E-03 0,04485585 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 7,528E-03 0,04473994 ! regulation of helicase activity GO:0051095 11 6 0,000 7,528E-03 0,04462463 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 7,528E-03 0,04450992 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 7,528E-03 0,04439579 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 7,528E-03 0,04428224 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 7,528E-03 0,04416928 ! positive regulation of axon extension GO:0045773 8 6 0,000 7,528E-03 0,04405689 ! prostate gland development GO:0030850 9 6 0,000 7,528E-03 0,04394507 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 7,528E-03 0,04383382 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 7,528E-03 0,04372313 ! forebrain neuron differentiation GO:0021879 9 6 0,000 7,528E-03 0,04361299 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 7,528E-03 0,04350341 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 7,528E-03 0,04339438 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 7,528E-03 0,04328589 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 7,528E-03 0,04317795 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 7,528E-03 0,04307054 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 7,528E-03 0,04296367 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 7,528E-03 0,04285732 ! neuron adhesion GO:0007158 9 6 0,000 7,528E-03 0,0427515 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 7,528E-03 0,0426462 ! establishment of tissue polarity GO:0007164 7 6 0,000 7,528E-03 0,04254142 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 7,528E-03 0,04243715 ! signal peptide processing GO:0006465 8 6 0,000 7,528E-03 0,04233339 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 7,528E-03 0,04223014 ! mRNA stabilization GO:0048255 15 6 0,000 7,528E-03 0,04212739 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 7,528E-03 0,04202514 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 7,528E-03 0,04192338 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 7,528E-03 0,04182212 ! opsonization GO:0008228 8 6 0,000 7,528E-03 0,04172134 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 7,528E-03 0,04162105 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 7,528E-03 0,04152124 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 7,528E-03 0,04142191 ! protein amino acid dealkylation GO:0008214 11 6 0,000 7,528E-03 0,04132305 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 7,528E-03 0,04122466 ! photoreceptor cell development GO:0042461 10 6 0,000 7,528E-03 0,04112674 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 7,528E-03 0,04102928 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 7,528E-03 0,04093229 ! mechanosensory behavior GO:0007638 8 6 0,000 7,528E-03 0,04083575 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 7,528E-03 0,04073966 ! negative regulation of endocytosis GO:0045806 8 6 0,000 7,528E-03 0,04064403 ! response to interferon-gamma GO:0034341 12 6 0,000 7,528E-03 0,04054885 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 7,528E-03 0,04045411 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 7,528E-03 0,04035981 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 7,528E-03 0,04026595 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 7,528E-03 0,04017252 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 7,528E-03 0,04007953 ! cGMP-mediated signaling GO:0019934 10 6 0,000 7,528E-03 0,03998697 ! activation of MAPKKK activity GO:0000185 10 6 0,000 7,528E-03 0,03989483 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 7,528E-03 0,03980312 ! thymic T cell selection GO:0045061 12 6 0,000 7,528E-03 0,03971183 ! protein lipoylation GO:0009249 10 6 0,000 7,528E-03 0,03962096 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 7,528E-03 0,0395305 ! pigment granule organization GO:0048753 11 6 0,000 7,528E-03 0,03944045 ! drug transport GO:0015893 6 6 0,000 7,528E-03 0,03935081 ! cysteine metabolic process GO:0006534 7 6 0,000 7,528E-03 0,03926158 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 7,528E-03 0,03917275 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 7,528E-03 0,03908433 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 7,528E-03 0,0389963 ! histidine metabolic process GO:0006547 6 6 0,000 7,528E-03 0,03890867 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 7,528E-03 0,03882143 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 7,528E-03 0,03873458 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 7,528E-03 0,03864812 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 7,528E-03 0,03856204 ! adenohypophysis development GO:0021984 10 6 0,000 7,528E-03 0,03847635 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 7,528E-03 0,03839104 ! hyperosmotic response GO:0006972 8 6 0,000 7,528E-03 0,0383061 ! microtubule nucleation GO:0007020 10 6 0,000 7,528E-03 0,03822154 ! ER overload response GO:0006983 7 6 0,000 7,528E-03 0,03813735 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 7,528E-03 0,03805353 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 7,528E-03 0,03797008 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 7,528E-03 0,037887 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 7,528E-03 0,03780427 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 7,528E-03 0,03772191 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 7,528E-03 0,03763991 ! response to dietary excess GO:0002021 7 6 0,000 7,528E-03 0,03755826 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 7,528E-03 0,03747696 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 7,528E-03 0,03739602 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 7,528E-03 0,03731543 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 7,528E-03 0,03723518 ! glycerol ether catabolic process GO:0044269 8 6 0,000 7,528E-03 0,03715527 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 7,528E-03 0,03707571 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 7,528E-03 0,03699649 ! neuron apoptosis GO:0051402 8 6 0,000 7,528E-03 0,03691761 ! organic alcohol transport GO:0015850 9 6 0,000 7,528E-03 0,03683906 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 7,528E-03 0,03676084 ! T cell mediated immunity GO:0002456 12 6 0,000 7,528E-03 0,03668296 ! male sex determination GO:0030238 9 6 0,000 7,528E-03 0,03660541 ! carnitine transport GO:0015879 8 6 0,000 7,528E-03 0,03652818 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 7,528E-03 0,03645128 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 7,528E-03 0,0363747 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 7,528E-03 0,03629844 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 7,528E-03 0,03622251 ! positive regulation of exocytosis GO:0045921 6 6 0,000 7,528E-03 0,03614688 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 7,528E-03 0,03607158 ! parturition GO:0007567 12 6 0,000 7,528E-03 0,03599659 ! negative regulation of translational initiation GO:0045947 7 6 0,000 7,528E-03 0,0359219 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 7,528E-03 0,03584753 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 7,528E-03 0,03577347 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 7,528E-03 0,03569971 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 7,528E-03 0,03562625 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 7,528E-03 0,0355531 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 7,528E-03 0,03548024 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 7,528E-03 0,03540768 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 7,528E-03 0,03533542 ! macrophage differentiation GO:0030225 10 6 0,000 7,528E-03 0,03526346 ! astrocyte development GO:0014002 14 6 0,000 7,528E-03 0,03519178 ! hyaluronan metabolic process GO:0030212 6 6 0,000 7,528E-03 0,0351204 ! purine base biosynthetic process GO:0009113 14 6 0,000 7,528E-03 0,03504931 ! interaction with symbiont GO:0051702 8 6 0,000 7,528E-03 0,0349785 ! anterograde axon cargo transport GO:0008089 8 6 0,000 7,528E-03 0,03490798 ! skeletal muscle contraction GO:0003009 6 6 0,000 7,528E-03 0,03483774 ! eating behavior GO:0042755 6 6 0,000 7,528E-03 0,03476779 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 7,528E-03 0,03469811 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 7,528E-03 0,03462872 ! response to copper ion GO:0046688 9 6 0,000 7,528E-03 0,0345596 ! DNA topological change GO:0006265 8 6 0,000 7,528E-03 0,03449075 ! response to exogenous dsRNA GO:0043330 8 6 0,000 7,528E-03 0,03442218 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 7,528E-03 0,03435388 ! establishment of melanosome localization GO:0032401 9 6 0,000 7,528E-03 0,03428586 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 7,528E-03 0,0342181 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 7,528E-03 0,03415061 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 7,528E-03 0,03408338 ! nucleoside catabolic process GO:0009164 6 6 0,000 7,528E-03 0,03401642 ! gas homeostasis GO:0033483 11 6 0,000 7,528E-03 0,03394972 ! hair follicle maturation GO:0048820 7 6 0,000 7,528E-03 0,03388328 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 7,528E-03 0,0338171 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 7,528E-03 0,03375118 ! Schwann cell development GO:0014044 14 6 0,000 7,528E-03 0,03368552 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 7,528E-03 0,03362011 ! dendrite morphogenesis GO:0048813 9 6 0,000 7,528E-03 0,03355496 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 7,528E-03 0,03349005 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 7,528E-03 0,0334254 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 7,528E-03 0,033361 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 7,528E-03 0,03329684 ! histone ubiquitination GO:0016574 7 6 0,000 7,528E-03 0,03323293 ! regulation of meiosis GO:0040020 10 6 0,000 7,528E-03 0,03316927 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 7,528E-03 0,03310585 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 7,528E-03 0,03304267 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 7,528E-03 0,03297973 ! regulation of mast cell activation GO:0033003 6 6 0,000 7,528E-03 0,03291703 ! membrane to membrane docking GO:0022614 12 6 0,000 7,528E-03 0,03285457 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 7,528E-03 0,03279234 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 7,528E-03 0,03273035 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 7,528E-03 0,0326686 ! receptor internalization GO:0031623 9 6 0,000 7,528E-03 0,03260708 ! neutrophil homeostasis GO:0001780 6 6 0,000 7,528E-03 0,03254578 ! coenzyme A metabolic process GO:0015936 9 6 0,000 7,528E-03 0,03248472 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 7,528E-03 0,03242389 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 7,528E-03 0,03236329 ! protein deubiquitination GO:0016579 8 6 0,000 7,528E-03 0,03230291 GO:0070646|protein modification by small protein removal, ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 7,528E-03 0,03224275 ! peptidyl-histidine modification GO:0018202 9 6 0,000 7,528E-03 0,03218282 ! axonal fasciculation GO:0007413 9 6 0,000 7,528E-03 0,03212311 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 7,528E-03 0,03206363 ! thiamin metabolic process GO:0006772 6 6 0,000 7,528E-03 0,03200436 ! midbrain development GO:0030901 6 6 0,000 7,528E-03 0,03194531 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 7,528E-03 0,03188648 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 7,528E-03 0,03182786 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 7,528E-03 0,03176946 ! progesterone metabolic process GO:0042448 8 6 0,000 7,528E-03 0,03171128 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 7,528E-03 0,0316533 ! glycolipid catabolic process GO:0019377 13 6 0,000 7,528E-03 0,03159554 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 7,528E-03 0,03153799 ! positive regulation of glucose import GO:0046326 6 6 0,000 7,528E-03 0,03148065 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 7,528E-03 0,03142352 ! adult feeding behavior GO:0008343 6 6 0,000 7,528E-03 0,03136659 ! blastocyst growth GO:0001832 15 6 0,000 7,528E-03 0,03130987 ! pigment granule transport GO:0051904 12 6 0,000 7,528E-03 0,03125335 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 7,528E-03 0,03119704 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 7,528E-03 0,03114093 ! catecholamine transport GO:0051937 7 6 0,000 7,528E-03 0,03108502 ! organ or tissue specific immune response GO:0002251 7 6 0,000 7,528E-03 0,03102931 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 7,528E-03 0,03097381 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 7,528E-03 0,0309185 ! negative regulation of B cell activation GO:0050869 9 6 0,000 7,528E-03 0,03086338 ! protein prenylation GO:0018342 10 6 0,000 7,528E-03 0,03080847 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 7,528E-03 0,03075374 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 7,528E-03 0,03069922 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 7,528E-03 0,03064488 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 7,528E-03 0,03059074 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 8,777E-03 0,03560487 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 8,777E-03 0,03554218 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 8,777E-03 0,03547972 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 8,777E-03 0,03541747 ! synaptonemal complex assembly GO:0007130 10 7 0,000 8,777E-03 0,03535545 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 8,777E-03 0,03529364 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 8,777E-03 0,03523204 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 8,777E-03 0,03517066 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 8,777E-03 0,0351095 ! reproductive behavior GO:0019098 12 7 0,000 8,777E-03 0,03504854 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 8,777E-03 0,0349878 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 8,777E-03 0,03492727 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 8,777E-03 0,03486694 ! oligopeptide transport GO:0006857 11 7 0,000 8,777E-03 0,03480683 ! protein amino acid sulfation GO:0006477 9 7 0,000 8,777E-03 0,03474692 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 8,777E-03 0,03468722 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 8,777E-03 0,03462772 ! RNA methylation GO:0001510 11 7 0,000 8,777E-03 0,03456843 ! pericardium development GO:0060039 8 7 0,000 8,777E-03 0,03450933 ! macrophage chemotaxis GO:0048246 10 7 0,000 8,777E-03 0,03445044 ! fibril organization GO:0043206 13 7 0,000 8,777E-03 0,03439176 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 8,777E-03 0,03433327 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 8,777E-03 0,03427498 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 8,777E-03 0,03421688 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 8,777E-03 0,03415899 ! lipoprotein transport GO:0042953 9 7 0,000 8,777E-03 0,03410128 ! cerebral cortex cell migration GO:0021795 11 7 0,000 8,777E-03 0,03404378 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 8,777E-03 0,03398647 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 8,777E-03 0,03392935 ! estrogen metabolic process GO:0008210 14 7 0,000 8,777E-03 0,03387242 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 8,777E-03 0,03381568 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 8,777E-03 0,03375913 ! chemosensory behavior GO:0007635 9 7 0,000 8,777E-03 0,03370277 ! microtubule bundle formation GO:0001578 8 7 0,000 8,777E-03 0,0336466 ! T-helper 1 type immune response GO:0042088 11 7 0,000 8,777E-03 0,03359062 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 8,777E-03 0,03353482 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 8,777E-03 0,0334792 ! leukocyte degranulation GO:0043299 10 7 0,000 8,777E-03 0,03342378 ! bile acid and bile salt transport GO:0015721 9 7 0,000 8,777E-03 0,03336853 ! reflex GO:0060004 12 7 0,000 8,777E-03 0,03331347 ! positive regulation of isotype switching GO:0045830 15 7 0,000 8,777E-03 0,03325858 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 8,777E-03 0,03320388 ! protein-cofactor linkage GO:0018065 13 7 0,000 8,777E-03 0,03314936 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 8,777E-03 0,03309502 ! glycerolipid catabolic process GO:0046503 9 7 0,000 8,777E-03 0,03304085 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 8,777E-03 0,03298686 ! spinal cord patterning GO:0021511 7 7 0,000 8,777E-03 0,03293305 ! hemoglobin metabolic process GO:0020027 10 7 0,000 8,777E-03 0,03287941 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 8,777E-03 0,03282595 ! adrenal gland development GO:0030325 17 7 0,000 8,777E-03 0,03277266 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 8,777E-03 0,03271955 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 8,777E-03 0,0326666 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 8,777E-03 0,03261383 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 8,777E-03 0,03256123 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 8,777E-03 0,03250879 ! endosome organization GO:0007032 10 7 0,000 8,777E-03 0,03245653 ! thyroid hormone generation GO:0006590 11 7 0,000 8,777E-03 0,03240443 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 8,777E-03 0,0323525 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 8,777E-03 0,03230074 ! regulation of pigmentation during development GO:0048070 15 7 0,000 8,777E-03 0,03224914 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 8,777E-03 0,0321977 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 8,777E-03 0,03214643 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 8,777E-03 0,03209533 ! galactose metabolic process GO:0006012 10 7 0,000 8,777E-03 0,03204438 ! vesicle fusion GO:0006906 15 7 0,000 8,777E-03 0,0319936 ! intracellular pH reduction GO:0051452 10 7 0,000 8,777E-03 0,03194298 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 8,777E-03 0,03189251 ! organ growth GO:0035265 11 7 0,000 8,777E-03 0,03184221 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 8,777E-03 0,03179206 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 8,777E-03 0,03174208 ! Rac protein signal transduction GO:0016601 7 7 0,000 8,777E-03 0,03169225 ! retinol metabolic process GO:0042572 9 7 0,000 8,777E-03 0,03164257 ! behavioral fear response GO:0001662 13 7 0,000 8,777E-03 0,03159305 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 8,777E-03 0,03154369 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 8,777E-03 0,03149448 ! rRNA modification GO:0000154 12 7 0,000 8,777E-03 0,03144542 ! protein heterooligomerization GO:0051291 10 7 0,000 8,777E-03 0,03139652 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 8,777E-03 0,03134776 ! response to UV-B GO:0010224 11 7 0,000 8,777E-03 0,03129916 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 8,777E-03 0,03125071 ! protein retention in ER lumen GO:0006621 12 7 0,000 8,777E-03 0,03120241 ! intermediate filament organization GO:0045109 11 7 0,000 8,777E-03 0,03115426 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 8,777E-03 0,03110626 ! cardiac muscle cell development GO:0055013 9 7 0,000 8,777E-03 0,0310584 ! fibrinolysis GO:0042730 9 7 0,000 8,777E-03 0,03101069 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 8,777E-03 0,03096313 ! regulation of circadian rhythm GO:0042752 11 7 0,000 8,777E-03 0,03091571 ! B cell lineage commitment GO:0002326 17 7 0,000 8,777E-03 0,03086844 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 8,777E-03 0,03082131 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 8,777E-03 0,03077433 ! response to tropane GO:0014073 13 7 0,000 8,777E-03 0,03072749 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 8,777E-03 0,03068079 ! melanosome localization GO:0032400 10 7 0,000 8,777E-03 0,03063423 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 8,777E-03 0,03058782 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 8,777E-03 0,03054154 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 8,777E-03 0,03049541 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 8,777E-03 0,03044941 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 8,777E-03 0,03040355 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 8,777E-03 0,03035784 ! mast cell activation GO:0045576 9 7 0,000 8,777E-03 0,03031225 ! multicellular organismal aging GO:0010259 11 7 0,000 8,777E-03 0,03026681 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 8,777E-03 0,0302215 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 8,777E-03 0,03017632 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 8,777E-03 0,03013128 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 8,777E-03 0,03008638 ! establishment of nucleus localization GO:0040023 13 7 0,000 8,777E-03 0,03004161 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 8,777E-03 0,02999697 ! T cell lineage commitment GO:0002360 12 7 0,000 8,777E-03 0,02995246 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 8,777E-03 0,02990809 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 8,777E-03 0,02986385 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 8,777E-03 0,02981973 ! response to tumor cell GO:0002347 12 7 0,000 8,777E-03 0,02977575 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 8,777E-03 0,0297319 ! neuroblast proliferation GO:0007405 13 7 0,000 8,777E-03 0,02968818 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 8,777E-03 0,02964458 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 8,777E-03 0,02960112 ! peptidyl-threonine modification GO:0018210 18 7 0,000 8,777E-03 0,02955778 ! diuresis GO:0030146 12 7 0,000 8,777E-03 0,02951456 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 8,777E-03 0,02947148 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 8,777E-03 0,02942851 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 8,777E-03 0,02938568 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 8,777E-03 0,02934297 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 8,777E-03 0,02930038 ! melanin biosynthetic process GO:0042438 8 7 0,000 8,777E-03 0,02925791 ! regulation of synaptogenesis GO:0051963 10 7 0,000 8,777E-03 0,02921557 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 8,777E-03 0,02917335 ! dopamine biosynthetic process GO:0042416 15 7 0,000 8,777E-03 0,02913126 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 8,777E-03 0,02908928 ! lymph node development GO:0048535 9 7 0,000 8,777E-03 0,02904743 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 8,777E-03 0,02900569 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 8,777E-03 0,02896408 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 8,777E-03 0,02892258 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 8,777E-03 0,0288812 ! endosome to lysosome transport GO:0008333 10 7 0,000 8,777E-03 0,02883994 ! ATP catabolic process GO:0006200 10 7 0,000 8,777E-03 0,0287988 ! establishment of pigment granule localization GO:0051905 13 7 0,000 8,777E-03 0,02875778 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 8,777E-03 0,02871687 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 8,777E-03 0,02867608 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 8,777E-03 0,0286354 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 8,777E-03 0,02859484 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 8,777E-03 0,0285544 ! muscle adaptation GO:0043500 12 7 0,000 8,777E-03 0,02851407 ! amino sugar catabolic process GO:0046348 9 7 0,000 8,777E-03 0,02847385 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 8,777E-03 0,02843375 ! retina homeostasis GO:0001895 9 7 0,000 8,777E-03 0,02839376 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 8,777E-03 0,02835388 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 8,777E-03 0,02831411 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 8,777E-03 0,02827445 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 8,777E-03 0,02823491 ! behavioral response to nicotine GO:0035095 11 7 0,000 8,777E-03 0,02819548 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 8,777E-03 0,02815615 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 8,777E-03 0,02811694 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,01002527 0,03206969 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,01002527 0,03202515 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 0,01002527 0,03198074 ! axon extension GO:0048675 11 8 0,000 0,01002527 0,03193644 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,01002527 0,03189227 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,01002527 0,03184822 ! associative learning GO:0008306 15 8 0,000 0,01002527 0,03180429 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,01002527 0,03176048 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,01002527 0,0317168 ! positive regulation of B cell proliferation GO:0030890 11 8 0,000 0,01002527 0,03167323 ! phosphate transport GO:0006817 10 8 0,000 0,01002527 0,03162978 ! N-glycan processing GO:0006491 12 8 0,000 0,01002527 0,03158645 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,01002527 0,03154324 ! UTP metabolic process GO:0046051 8 8 0,000 0,01002527 0,03150015 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,01002527 0,03145718 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,01002527 0,03141432 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,01002527 0,03137158 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,01002527 0,03132895 ! succinate metabolic process GO:0006105 14 8 0,000 0,01002527 0,03128645 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,01002527 0,03124405 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,01002527 0,03120177 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01002527 0,03115961 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,01002527 0,03111756 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,01002527 0,03107562 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,01002527 0,0310338 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,01002527 0,03099208 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,01002527 0,03095048 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01002527 0,03090899 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,01002527 0,03086762 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,01002527 0,03082635 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,01002527 0,03078519 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,01002527 0,03074415 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,01002527 0,03070321 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,01002527 0,03066238 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,01002527 0,03062166 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,01002527 0,03058105 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 0,000 0,01002527 0,03054054 ! astrocyte differentiation GO:0048708 16 8 0,000 0,01002527 0,03050015 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,01002527 0,03045985 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,01002527 0,03041967 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,01002527 0,03037959 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,01002527 0,03033962 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,01002527 0,03029975 ! melanin metabolic process GO:0006582 12 8 0,000 0,01002527 0,03025999 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,01002527 0,03022033 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01002527 0,03018077 ! macrophage activation GO:0042116 12 8 0,000 0,01002527 0,03014132 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,01002527 0,03010197 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,01002527 0,03006273 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,01002527 0,03002358 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,01002527 0,02998454 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01002527 0,0299456 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,01002527 0,02990676 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,01002527 0,02986802 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,01002527 0,02982938 ! ruffle organization GO:0031529 11 8 0,000 0,01002527 0,02979084 ! osteoblast development GO:0002076 13 8 0,000 0,01002527 0,0297524 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,01002527 0,02971406 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,01002527 0,02967582 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,01002527 0,02963767 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,01002527 0,02959963 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,01002527 0,02956168 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,01002527 0,02952383 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,01002527 0,02948607 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,01002527 0,02944842 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,01002527 0,02941085 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,01002527 0,02937339 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,01002527 0,02933602 ! oligodendrocyte development GO:0014003 8 8 0,000 0,01002527 0,02929874 ! segment specification GO:0007379 10 8 0,000 0,01002527 0,02926156 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,01002527 0,02922447 ! cellular extravasation GO:0045123 11 8 0,000 0,01002527 0,02918748 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,01002527 0,02915058 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,01002527 0,02911378 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,01002527 0,02907706 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,01002527 0,02904044 ! snRNA metabolic process GO:0016073 10 8 0,000 0,01002527 0,02900391 GO:0016180|snRNA processing, ! phosphoinositide 3-kinase cascade GO:0014065 23 8 0,000 0,01002527 0,02896748 ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,01002527 0,02893113 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,01002527 0,02889487 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,01002527 0,02885871 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,01002527 0,02882264 ! nucleosome disassembly GO:0006337 12 8 0,000 0,01002527 0,02878665 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,01002527 0,02875076 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,01002527 0,02871496 ! icosanoid secretion GO:0032309 12 8 0,000 0,01002527 0,02867924 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,01002527 0,02864362 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01002527 0,02860808 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,01002527 0,02857263 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,01002527 0,02853727 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,01002527 0,02850199 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,01002527 0,0284668 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,01002527 0,0284317 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,01002527 0,02839669 ! sterol catabolic process GO:0016127 9 8 0,000 0,01002527 0,02836176 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,01002527 0,02832692 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,01002527 0,02829216 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,01002527 0,02825749 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,01002527 0,0282229 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01002527 0,0281884 ! prophase GO:0051324 11 8 0,000 0,01002527 0,02815398 ! S phase GO:0051320 8 8 0,000 0,01002527 0,02811965 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,01002527 0,0280854 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,01002527 0,02805123 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,01002527 0,02801714 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,01002527 0,02798314 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,01002527 0,02794922 ! hormone catabolic process GO:0042447 13 8 0,000 0,01002527 0,02791539 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,01002527 0,02788163 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,01002527 0,02784796 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,01002527 0,02781437 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,01002527 0,02778086 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,01002527 0,02774742 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01002527 0,02771407 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,01002527 0,0276808 ! lamellipodium assembly GO:0030032 9 8 0,000 0,01002527 0,02764761 ! regulation of embryonic development GO:0045995 16 8 0,000 0,01002527 0,0276145 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01002527 0,02758147 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,01002527 0,02754852 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,01002527 0,02751564 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,01127166 0,03089965 ! regulation of developmental growth GO:0048638 13 9 0,000 0,01127166 0,03086287 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,01127166 0,03082617 ! telencephalon cell migration GO:0022029 16 9 0,000 0,01127166 0,03078956 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,01127166 0,03075304 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,01127166 0,0307166 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,01127166 0,03068025 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,01127166 0,03064398 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,01127166 0,0306078 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,01127166 0,03057171 ! GTP metabolic process GO:0046039 9 9 0,000 0,01127166 0,0305357 ! elastic fiber assembly GO:0048251 13 9 0,000 0,01127166 0,03049978 ! social behavior GO:0035176 14 9 0,000 0,01127166 0,03046394 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,01127166 0,03042818 ! artery development GO:0060840 19 9 0,000 0,01127166 0,03039251 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,01127166 0,03035692 ! regulation of glycolysis GO:0006110 15 9 0,000 0,01127166 0,03032142 ! response to pain GO:0048265 16 9 0,000 0,01127166 0,03028599 ! protein complex disassembly GO:0043241 17 9 0,000 0,01127166 0,03025065 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,01127166 0,0302154 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,01127166 0,03018022 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,01127166 0,03014513 ! lung alveolus development GO:0048286 17 9 0,000 0,01127166 0,03011012 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,01127166 0,03007519 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,01127166 0,03004034 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,01127166 0,03000557 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,01127166 0,02997088 ! ventral spinal cord development GO:0021517 11 9 0,000 0,01127166 0,02993627 ! protein targeting to ER GO:0045047 19 9 0,000 0,01127166 0,02990174 ! T cell selection GO:0045058 18 9 0,000 0,01127166 0,02986729 ! endoderm development GO:0007492 12 9 0,000 0,01127166 0,02983292 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,01127166 0,02979863 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,01127166 0,02976442 ! arginine catabolic process GO:0006527 10 9 0,000 0,01127166 0,02973029 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,01127166 0,02969623 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,01127166 0,02966225 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,01127166 0,02962835 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01127166 0,02959453 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,01127166 0,02956079 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,01127166 0,02952712 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01127166 0,02949353 ! mannose metabolic process GO:0006013 9 9 0,000 0,01127166 0,02946001 ! receptor clustering GO:0043113 15 9 0,000 0,01127166 0,02942657 ! epithelial cell development GO:0002064 10 9 0,000 0,01127166 0,02939321 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,01127166 0,02935992 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,01127166 0,02932671 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,01127166 0,02929357 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,01127166 0,02926051 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,01127166 0,02922752 ! motor axon guidance GO:0008045 14 9 0,000 0,01127166 0,02919461 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,01127166 0,02916177 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,01127166 0,029129 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,01127166 0,02909631 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,01127166 0,02906369 ! blastoderm segmentation GO:0007350 11 9 0,000 0,01127166 0,02903114 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,01127166 0,02899867 ! DNA ligation GO:0006266 14 9 0,000 0,01127166 0,02896627 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,01127166 0,02893394 ! response to amine stimulus GO:0014075 13 9 0,000 0,01127166 0,02890168 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,01127166 0,0288695 ! erythrocyte development GO:0048821 11 9 0,000 0,01127166 0,02883739 ! renal water homeostasis GO:0003091 14 9 0,000 0,01127166 0,02880534 ! postreplication repair GO:0006301 11 9 0,000 0,01127166 0,02877337 ! mRNA cleavage GO:0006379 13 9 0,000 0,01127166 0,02874148 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,01127166 0,02870965 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,01127166 0,02867789 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,01127166 0,0286462 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,01127166 0,02861458 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,01127166 0,02858303 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,01127166 0,02855155 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,01127166 0,02852014 ! acid secretion GO:0046717 14 9 0,000 0,01127166 0,0284888 ! musculoskeletal movement GO:0050881 11 9 0,000 0,01127166 0,02845753 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,01127166 0,02842633 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,01127166 0,02839519 ! purine base metabolic process GO:0006144 18 9 0,000 0,01127166 0,02836413 ! oocyte differentiation GO:0009994 12 9 0,000 0,01127166 0,02833313 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,01127166 0,02830219 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,01127166 0,02827133 ! spleen development GO:0048536 15 9 0,000 0,01127166 0,02824053 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,01127166 0,0282098 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,01127166 0,02817914 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,01127166 0,02814855 ! detection of calcium ion GO:0005513 13 9 0,000 0,01127166 0,02811802 ! blastocyst formation GO:0001825 12 9 0,000 0,01127166 0,02808755 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,01127166 0,02805715 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,01127166 0,02802682 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,01127166 0,02799656 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,01127166 0,02796635 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01127166 0,02793622 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,01127166 0,02790615 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,01127166 0,02787614 ! prepulse inhibition GO:0060134 14 9 0,000 0,01127166 0,0278462 ! embryonic placenta development GO:0001892 12 9 0,000 0,01127166 0,02781632 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,01127166 0,02778651 ! insulin secretion GO:0030073 17 9 0,000 0,01127166 0,02775676 ! sequestering of metal ion GO:0051238 11 9 0,000 0,01127166 0,02772707 ! response to nicotine GO:0035094 16 9 0,000 0,01127166 0,02769745 ! establishment of cell polarity GO:0030010 12 9 0,000 0,01127166 0,02766789 ! nucleus localization GO:0051647 15 9 0,000 0,01127166 0,02763839 ! regulation of synapse organization GO:0050807 12 9 0,000 0,01127166 0,02760896 ! localization within membrane GO:0051668 15 9 0,000 0,01127166 0,02757959 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,01251655 0,03059306 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,01251655 0,03056058 ! neuron fate specification GO:0048665 11 10 0,000 0,01251655 0,03052817 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,01251655 0,03049583 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,01251655 0,03046356 ! thyroid gland development GO:0030878 19 10 0,000 0,01251655 0,03043136 ! regulation of B cell proliferation GO:0030888 15 10 0,000 0,01251655 0,03039922 ! synapsis GO:0007129 13 10 0,000 0,01251655 0,03036716 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,01251655 0,03033516 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,01251655 0,03030323 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,01251655 0,03027136 ! sulfate transport GO:0008272 12 10 0,000 0,01251655 0,03023956 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,01251655 0,03020783 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,01251655 0,03017617 ! androgen metabolic process GO:0008209 13 10 0,000 0,01251655 0,03014457 ! phospholipid efflux GO:0033700 16 10 0,000 0,01251655 0,03011304 ! hippocampus development GO:0021766 19 10 0,000 0,01251655 0,03008157 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,01251655 0,03005017 ! blood vessel remodeling GO:0001974 21 10 0,000 0,01251655 0,03001884 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,01251655 0,02998757 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,01251655 0,02995636 ! pathogenesis GO:0009405 13 10 0,000 0,01251655 0,02992522 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,01251655 0,02989415 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01251655 0,02986314 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,01251655 0,02983219 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 0,01251655 0,02980131 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,01251655 0,02977049 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,01251655 0,02973974 ! melanocyte differentiation GO:0030318 15 10 0,000 0,01251655 0,02970905 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,01251655 0,02967842 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,01251655 0,02964785 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,01251655 0,02961735 ! response to X-ray GO:0010165 16 10 0,000 0,01251655 0,02958691 ! B cell proliferation GO:0042100 14 10 0,000 0,01251655 0,02955654 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,01251655 0,02952622 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,01251655 0,02949597 ! forebrain cell migration GO:0021885 17 10 0,000 0,01251655 0,02946578 ! lipid digestion GO:0044241 15 10 0,000 0,01251655 0,02943565 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,01251655 0,02940558 ! UV protection GO:0009650 14 10 0,000 0,01251655 0,02937558 ! entry into host cell GO:0030260 20 10 0,000 0,01251655 0,02934563 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,01251655 0,02931575 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,01251655 0,02928593 ! negative regulation of ossification GO:0030279 19 10 0,000 0,01251655 0,02925616 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,01251655 0,02922646 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,01251655 0,02919682 ! regulation of bone resorption GO:0045124 24 10 0,000 0,01251655 0,02916724 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,01251655 0,02913772 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,01251655 0,02910826 ! regulation of organ growth GO:0046620 11 10 0,000 0,01251655 0,02907885 ! response to dsRNA GO:0043331 18 10 0,000 0,01251655 0,02904951 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,01251655 0,02902023 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,01251655 0,028991 ! embryonic axis specification GO:0000578 12 10 0,000 0,01251655 0,02896184 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,01251655 0,02893273 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,01251655 0,02890368 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,01251655 0,02887469 ! cranial nerve development GO:0021545 12 10 0,000 0,01251655 0,02884576 ! fucose catabolic process GO:0019317 16 10 0,000 0,01251655 0,02881688 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,01251655 0,02878807 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,01251655 0,02875931 ! protein sumoylation GO:0016925 12 10 0,000 0,01251655 0,0287306 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,01251655 0,02870196 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01251655 0,02867337 ! zymogen activation GO:0031638 14 10 0,000 0,01251655 0,02864484 ! salivary gland development GO:0007431 22 10 0,000 0,01251655 0,02861637 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,01251655 0,02858795 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,01251655 0,02855959 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,01251655 0,02853128 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,01251655 0,02850304 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,01251655 0,02847484 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,01251655 0,0284467 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,01251655 0,02841862 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,01251655 0,0283906 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,01251655 0,02836263 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,01251655 0,02833471 ! detection of bacterium GO:0016045 10 10 0,000 0,01251655 0,02830685 ! embryonic gut development GO:0048566 11 10 0,000 0,01251655 0,02827904 ! activation of innate immune response GO:0002218 10 10 0,000 0,01251655 0,02825129 GO:0002758|innate immune response-activating signal transduction, ! cardiac cell differentiation GO:0035051 16 10 0,000 0,01251655 0,02822359 ! developmental induction GO:0031128 13 10 0,000 0,01251655 0,02819595 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,01251655 0,02816836 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,01251655 0,02814083 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,01251655 0,02811335 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,01251655 0,02808592 ! rRNA transcription GO:0009303 17 11 0,000 0,01375995 0,03084589 ! respiratory burst GO:0045730 14 11 0,000 0,01375995 0,03081585 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,01375995 0,03078587 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,01375995 0,03075596 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,01375995 0,0307261 ! virus-host interaction GO:0019048 17 11 0,000 0,01375995 0,03069629 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 0,01375995 0,03066655 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,01375995 0,03063686 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,01375995 0,03060723 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,01375995 0,03057766 ! RNA polyadenylation GO:0043631 19 11 0,000 0,01375995 0,03054815 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,01375995 0,03051869 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,01375995 0,03048929 ! mating GO:0007618 14 11 0,000 0,01375995 0,03045994 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,01375995 0,03043065 ! T cell proliferation GO:0042098 20 11 0,000 0,01375995 0,03040142 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,01375995 0,03037224 ! bone resorption GO:0045453 16 11 0,000 0,01375995 0,03034312 ! regulated secretory pathway GO:0045055 14 11 0,000 0,01375995 0,03031406 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,01375995 0,03028505 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,01375995 0,0302561 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,01375995 0,0302272 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,01375995 0,03019836 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,01375995 0,03016957 ! syncytium formation GO:0006949 15 11 0,000 0,01375995 0,03014084 ! plasma membrane organization GO:0007009 18 11 0,000 0,01375995 0,03011216 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,01375995 0,03008354 ! focal adhesion formation GO:0048041 24 11 0,000 0,01375995 0,03005497 ! mitotic spindle organization GO:0007052 15 11 0,000 0,01375995 0,03002645 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,01375995 0,02999799 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,01375995 0,02996958 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,01375995 0,02994123 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,01375995 0,02991293 ! adult heart development GO:0007512 11 11 0,000 0,01375995 0,02988468 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,01375995 0,02985649 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,01375995 0,02982835 ! temperature homeostasis GO:0001659 16 11 0,000 0,01375995 0,02980026 ! L-glutamate transport GO:0015813 16 11 0,000 0,01375995 0,02977223 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,01375995 0,02974425 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,01375995 0,02971632 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,01375995 0,02968844 ! stem cell development GO:0048864 29 11 0,000 0,01375995 0,02966062 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,01375995 0,02963285 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,01375995 0,02960513 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,01375995 0,02957746 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,01375995 0,02954984 ! vasoconstriction GO:0042310 15 11 0,000 0,01375995 0,02952228 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,01375995 0,02949476 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,01375995 0,0294673 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,01375995 0,02943989 ! ribosome assembly GO:0042255 13 11 0,000 0,01375995 0,02941253 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,01375995 0,02938522 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,01375995 0,02935796 ! chromatin silencing GO:0006342 19 11 0,000 0,01375995 0,02933075 ! nucleosome positioning GO:0016584 13 11 0,000 0,01375995 0,02930359 ! T cell homeostasis GO:0043029 20 11 0,000 0,01375995 0,02927648 ! regulation of isotype switching GO:0045191 19 11 0,000 0,01375995 0,02924943 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,01375995 0,02922242 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,01375995 0,02919546 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,01375995 0,02916855 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,01375995 0,02914169 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,01375995 0,02911488 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,01375995 0,02908812 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,01375995 0,02906141 ! male genitalia development GO:0030539 13 11 0,000 0,01375995 0,02903475 ! cholesterol efflux GO:0033344 19 11 0,000 0,01375995 0,02900814 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,01375995 0,02898157 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,01375995 0,02895506 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,01375995 0,02892859 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,01375995 0,02890217 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,01375995 0,0288758 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,01375995 0,02884948 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,01375995 0,0288232 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,01375995 0,02879698 ! lysogeny GO:0030069 18 11 0,000 0,01375995 0,0287708 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,01375995 0,02874467 ! acrosome reaction GO:0007340 13 11 0,000 0,01375995 0,02871858 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,01375995 0,02869255 ! lactation GO:0007595 20 12 0,000 0,01500185 0,03125385 ! reproductive cellular process GO:0048610 14 12 0,000 0,01500185 0,03122557 ! tRNA modification GO:0006400 14 12 0,000 0,01500185 0,03119734 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,01500185 0,03116916 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,01500185 0,03114102 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,01500185 0,03111294 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,01500185 0,03108491 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,01500185 0,03105694 ! non-recombinational repair GO:0000726 19 12 0,000 0,01500185 0,03102901 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,01500185 0,03100113 ! peroxisomal transport GO:0043574 21 12 0,000 0,01500185 0,0309733 ! cartilage condensation GO:0001502 18 12 0,000 0,01500185 0,03094552 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,01500185 0,03091779 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,01500185 0,03089011 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,01500185 0,03086248 ! heart looping GO:0001947 15 12 0,000 0,01500185 0,0308349 ! palate development GO:0060021 15 12 0,000 0,01500185 0,03080737 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,01500185 0,03077989 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,01500185 0,03075246 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,01500185 0,03072507 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,01500185 0,03069774 ! arginine metabolic process GO:0006525 13 12 0,000 0,01500185 0,03067045 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,01500185 0,03064321 ! methionine metabolic process GO:0006555 13 12 0,000 0,01500185 0,03061602 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,01500185 0,03058888 ! Golgi organization GO:0007030 18 12 0,000 0,01500185 0,03056178 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,01500185 0,03053474 ! monoamine transport GO:0015844 13 12 0,000 0,01500185 0,03050774 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01500185 0,03048079 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,01500185 0,03045389 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,01500185 0,03042703 ! L-amino acid transport GO:0015807 20 12 0,000 0,01500185 0,03040022 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,01500185 0,03037346 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,01500185 0,03034675 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,01500185 0,03032008 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,01500185 0,03029346 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,01500185 0,03026689 ! cerebellum development GO:0021549 13 12 0,000 0,01500185 0,03024036 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,01500185 0,03021388 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,01500185 0,03018745 ! histone acetylation GO:0016573 23 12 0,000 0,01500185 0,03016106 ! histone methylation GO:0016571 15 12 0,000 0,01500185 0,03013472 ! autonomic nervous system development GO:0048483 23 12 0,000 0,01500185 0,03010843 ! gland morphogenesis GO:0022612 23 12 0,000 0,01500185 0,03008218 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,01500185 0,03005597 ! peptidyl-lysine modification GO:0018205 18 12 0,000 0,01500185 0,03002981 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,01500185 0,0300037 ! response to gamma radiation GO:0010332 20 12 0,000 0,01500185 0,02997763 ! regulation of epidermis development GO:0045682 17 12 0,000 0,01500185 0,02995161 ! intestinal absorption GO:0050892 19 12 0,000 0,01500185 0,02992563 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,01500185 0,0298997 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,01500185 0,02987381 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,01500185 0,02984797 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,01500185 0,02982217 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,01500185 0,02979642 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,01500185 0,02977071 ! microspike assembly GO:0030035 23 12 0,000 0,01500185 0,02974505 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,01500185 0,02971943 ! response to cold GO:0009409 14 12 0,000 0,01500185 0,02969385 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 0,01624226 0,03212141 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,01624226 0,03209381 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,01624226 0,03206626 ! cGMP metabolic process GO:0046068 16 13 0,000 0,01624226 0,03203876 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,01624226 0,03201131 ! water transport GO:0006833 17 13 0,000 0,01624226 0,0319839 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,01624226 0,03195654 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,01624226 0,03192923 ! lipid localization GO:0010876 24 13 0,000 0,01624226 0,03190196 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,01624226 0,03187474 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,01624226 0,03184757 ! organelle fusion GO:0048284 28 13 0,000 0,01624226 0,03182044 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,01624226 0,03179336 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,01624226 0,03176632 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,01624226 0,03173934 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,01624226 0,03171239 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,01624226 0,03168549 ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,01624226 0,03165864 ! glutamate metabolic process GO:0006536 18 13 0,000 0,01624226 0,03163184 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,01624226 0,03160507 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,01624226 0,03157836 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,01624226 0,03155169 ! NAD metabolic process GO:0019674 21 13 0,000 0,01624226 0,03152506 ! exocrine system development GO:0035272 27 13 0,000 0,01624226 0,03149848 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,01624226 0,03147194 ! bone mineralization GO:0030282 15 13 0,000 0,01624226 0,03144545 ! regulation of exocytosis GO:0017157 17 13 0,000 0,01624226 0,03141901 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,01624226 0,0313926 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,01624226 0,03136624 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,01624226 0,03133993 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,01624226 0,03131366 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,01624226 0,03128744 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,01624226 0,03126125 ! genitalia development GO:0048806 15 13 0,000 0,01624226 0,03123512 ! regulation of cellular pH GO:0030641 20 13 0,000 0,01624226 0,03120902 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 0,01624226 0,03118297 ! cellular pigmentation GO:0033059 24 13 0,000 0,01624226 0,03115696 ! tissue regeneration GO:0042246 21 13 0,000 0,01624226 0,031131 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,01624226 0,03110508 ! cofactor transport GO:0051181 19 13 0,000 0,01624226 0,0310792 ! NADP metabolic process GO:0006739 18 13 0,000 0,01624226 0,03105336 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,01624226 0,03102757 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,01624226 0,03100182 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,01624226 0,03097612 ! gas transport GO:0015669 18 13 0,000 0,01624226 0,03095045 ! regulation of RNA stability GO:0043487 28 13 0,000 0,01624226 0,03092483 ! heme biosynthetic process GO:0006783 20 13 0,000 0,01624226 0,03089925 ! regulation of axon extension GO:0030516 23 13 0,000 0,01624226 0,03087372 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,01624226 0,03084822 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,01624226 0,03082277 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,01624226 0,03079736 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,01624226 0,03077199 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,01624226 0,03074666 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,01748118 0,03306473 ! superoxide anion generation GO:0042554 18 14 0,000 0,01748118 0,03303756 ! neuron maturation GO:0042551 21 14 0,000 0,01748118 0,03301044 ! regulation of S phase GO:0033261 18 14 0,000 0,01748118 0,03298336 ! myotube differentiation GO:0014902 21 14 0,000 0,01748118 0,03295632 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 0,01748118 0,03292933 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,01748118 0,03290238 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,01748118 0,03287548 ! inositol metabolic process GO:0006020 20 14 0,000 0,01748118 0,03284862 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,01748118 0,0328218 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,01748118 0,03279503 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,01748118 0,03276831 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,01748118 0,03274162 ! gene silencing by RNA GO:0031047 20 14 0,000 0,01748118 0,03271498 ! response to cAMP GO:0051591 19 14 0,000 0,01748118 0,03268838 ! limbic system development GO:0021761 25 14 0,000 0,01748118 0,03266183 ! startle response GO:0001964 21 14 0,000 0,01748118 0,03263532 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,01748118 0,03260885 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,01748118 0,03258242 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,01748118 0,03255604 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,01748118 0,0325297 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,01748118 0,0325034 ! glycine metabolic process GO:0006544 22 14 0,000 0,01748118 0,03247715 ! pituitary gland development GO:0021983 23 14 0,000 0,01748118 0,03245094 ! cellular response to starvation GO:0009267 21 14 0,000 0,01748118 0,03242477 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,01748118 0,03239864 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,01748118 0,03237255 ! regulation of heart rate GO:0002027 23 14 0,000 0,01748118 0,03234651 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,01748118 0,03232051 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,01748118 0,03229455 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,01748118 0,03226863 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,01748118 0,03224275 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,01748118 0,03221692 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,01748118 0,03219112 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,01748118 0,03216537 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,01748118 0,03213966 ! axon cargo transport GO:0008088 27 14 0,000 0,01748118 0,03211399 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,01748118 0,03208836 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,01748118 0,03206277 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,01748118 0,03203722 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,01748118 0,03201171 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,01748118 0,03198625 ! mRNA splice site selection GO:0006376 26 14 0,000 0,01748118 0,03196082 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,01748118 0,03193543 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,01748118 0,03191009 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,01748118 0,03188478 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,01748118 0,03185952 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,01748118 0,03183429 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,01748118 0,03180911 ! muscle maintenance GO:0046716 19 14 0,000 0,01748118 0,03178396 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,01748118 0,03175886 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,01748118 0,03173379 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,01748118 0,03170876 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,01748118 0,03168378 ! cell killing GO:0001906 20 14 0,000 0,01748118 0,03165883 ! release of cytochrome c from mitochondria GO:0001836 23 14 0,000 0,01748118 0,03163392 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,01748118 0,03160905 ! cilium assembly GO:0042384 20 14 0,000 0,01748118 0,03158422 ! peptide hormone secretion GO:0030072 23 14 0,000 0,01748118 0,03155943 ! positive regulation of cell size GO:0045793 20 15 0,000 0,01871861 0,0337669 ! metencephalon development GO:0022037 19 15 0,000 0,01871861 0,03374044 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,01871861 0,03371402 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,01871861 0,03368764 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,01871861 0,0336613 ! skin development GO:0043588 25 15 0,000 0,01871861 0,033635 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,01871861 0,03360874 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,01871861 0,03358253 ! lipid phosphorylation GO:0046834 23 15 0,000 0,01871861 0,03355635 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,01871861 0,03353022 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,01871861 0,03350412 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,01871861 0,03347807 ! bile acid metabolic process GO:0008206 22 15 0,000 0,01871861 0,03345206 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,01871861 0,03342609 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,01871861 0,03340015 ! adult walking behavior GO:0007628 25 15 0,000 0,01871861 0,03337426 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,01871861 0,03334841 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,01871861 0,0333226 ! myoblast differentiation GO:0045445 27 15 0,000 0,01871861 0,03329683 ! centrosome cycle GO:0007098 16 15 0,000 0,01871861 0,0332711 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,01871861 0,0332454 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,01871861 0,03321975 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,01871861 0,03319414 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,01871861 0,03316857 ! cerebral cortex development GO:0021987 29 15 0,000 0,01871861 0,03314303 ! response to osmotic stress GO:0006970 22 15 0,000 0,01871861 0,03311754 ! vesicle coating GO:0006901 25 15 0,000 0,01871861 0,03309208 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,01871861 0,03306667 ! DNA integration GO:0015074 22 15 0,000 0,01871861 0,03304129 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,01871861 0,03301595 ! peptide secretion GO:0002790 27 15 0,000 0,01871861 0,03299065 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,01871861 0,03296539 ! regulation of vasodilation GO:0042312 24 15 0,000 0,01871861 0,03294017 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,01871861 0,03291498 ! neuron recognition GO:0008038 22 15 0,000 0,01871861 0,03288984 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,01871861 0,03286473 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,01871861 0,03283966 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,01871861 0,03281463 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,01871861 0,03278964 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,01871861 0,03276469 ! biomineral formation GO:0031214 18 15 0,000 0,01871861 0,03273977 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,01871861 0,03271489 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,01871861 0,03269005 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,01871861 0,03266525 ! dopamine metabolic process GO:0042417 30 15 0,000 0,01871861 0,03264048 ! organic cation transport GO:0015695 19 15 0,000 0,01871861 0,03261576 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,01871861 0,03259107 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,01871861 0,03256641 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,01871861 0,0325418 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,01871861 0,03251722 ! defense response to virus GO:0051607 27 15 0,000 0,01871861 0,03249268 ! peptide hormone processing GO:0016486 19 15 0,000 0,01871861 0,03246817 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,01871861 0,03244371 ! protein secretion GO:0009306 27 16 0,000 0,01995455 0,03455984 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,01995455 0,03453383 ! hormone secretion GO:0046879 25 16 0,000 0,01995455 0,03450787 ! bone remodeling GO:0046849 24 16 0,000 0,01995455 0,03448194 ! endothelial cell migration GO:0043542 22 16 0,000 0,01995455 0,03445605 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,01995455 0,03443021 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,01995455 0,0344044 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,01995455 0,03437862 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,01995455 0,03435289 ! glial cell development GO:0021782 24 16 0,000 0,01995455 0,0343272 ! patterning of blood vessels GO:0001569 24 16 0,000 0,01995455 0,03430154 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,01995455 0,03427592 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,01995455 0,03425035 ! protein polyubiquitination GO:0000209 26 16 0,000 0,01995455 0,0342248 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,01995455 0,0341993 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,01995455 0,03417384 ! fructose metabolic process GO:0006000 20 16 0,000 0,01995455 0,03414841 ! regulation of protein binding GO:0043393 27 16 0,000 0,01995455 0,03412302 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,01995455 0,03409767 ! protein export from nucleus GO:0006611 24 16 0,000 0,01995455 0,03407236 ! negative regulation of immune response GO:0050777 28 16 0,000 0,01995455 0,03404708 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,01995455 0,03402184 ! DNA replication initiation GO:0006270 25 16 0,000 0,01995455 0,03399664 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,01995455 0,03397148 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,01995455 0,03394635 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,01995455 0,03392126 ! diencephalon development GO:0021536 25 16 0,000 0,01995455 0,03389621 ! oogenesis GO:0048477 23 16 0,000 0,01995455 0,03387119 ! neural crest cell migration GO:0001755 24 16 0,000 0,01995455 0,03384621 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,01995455 0,03382127 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,01995455 0,03379636 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,01995455 0,0337715 ! steroid catabolic process GO:0006706 22 16 0,000 0,01995455 0,03374666 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,01995455 0,03372187 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,01995455 0,03369711 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,01995455 0,03367239 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,01995455 0,0336477 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,01995455 0,03362305 ! sperm-egg recognition GO:0035036 16 16 0,000 0,01995455 0,03359844 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,01995455 0,03357386 ! nerve development GO:0021675 18 16 0,000 0,01995455 0,03354932 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,01995455 0,03352481 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,01995455 0,03350034 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,021189 0,03554684 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,021189 0,03552093 ! negative regulation of defense response GO:0031348 19 17 0,000 0,021189 0,03549506 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,021189 0,03546922 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,021189 0,03544343 ! glycerol metabolic process GO:0006071 20 17 0,000 0,021189 0,03541767 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,021189 0,03539195 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,021189 0,03536626 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,021189 0,03534062 ! signal complex assembly GO:0007172 29 17 0,000 0,021189 0,03531501 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,021189 0,03528944 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,021189 0,0352639 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,021189 0,0352384 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,021189 0,03521294 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,021189 0,03518752 ! memory GO:0007613 25 17 0,000 0,021189 0,03516213 ! keratinization GO:0031424 17 17 0,000 0,021189 0,03513678 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,021189 0,03511146 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,021189 0,03508619 ! retinoid metabolic process GO:0001523 22 17 0,000 0,021189 0,03506094 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,021189 0,03503574 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,021189 0,03501057 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,021189 0,03498544 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,021189 0,03496034 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,021189 0,03493528 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,021189 0,03491025 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 0,000 0,021189 0,03488526 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,021189 0,03486031 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,021189 0,03483539 ! membrane budding GO:0006900 29 17 0,000 0,021189 0,03481051 ! heme metabolic process GO:0042168 27 17 0,000 0,021189 0,03478566 ! actin filament bundle formation GO:0051017 26 17 0,000 0,021189 0,03476085 ! neuromuscular junction development GO:0007528 23 17 0,000 0,021189 0,03473607 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,021189 0,03471133 ! body fluid secretion GO:0007589 27 17 0,000 0,021189 0,03468663 ! stem cell differentiation GO:0048863 36 17 0,000 0,021189 0,03466196 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,021189 0,03463732 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,021189 0,03461272 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,021189 0,03458816 ! sensory perception of pain GO:0019233 23 17 0,000 0,021189 0,03456362 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,021189 0,03453913 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,021189 0,03451467 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,021189 0,03449024 ! synaptogenesis GO:0007416 24 17 0,000 0,021189 0,03446585 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,021189 0,03444149 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,021189 0,03441717 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,021189 0,03439288 ! cell-cell junction organization GO:0045216 25 17 0,000 0,021189 0,03436863 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,021189 0,03434441 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,021189 0,03432022 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,021189 0,03429607 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,021189 0,03427195 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,021189 0,03424786 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,02242198 0,03621527 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,02242198 0,03618986 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,02242198 0,03616448 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,02242198 0,03613913 ! cAMP metabolic process GO:0046058 33 18 0,000 0,02242198 0,03611383 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,02242198 0,03608855 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,02242198 0,03606332 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,02242198 0,03603812 ! axis specification GO:0009798 26 18 0,000 0,02242198 0,03601295 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,02242198 0,03598782 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,02242198 0,03596272 ! pancreas development GO:0031016 26 18 0,000 0,02242198 0,03593766 ! apoptotic mitochondrial changes GO:0008637 29 18 0,000 0,02242198 0,03591264 ! glutamine metabolic process GO:0006541 23 18 0,000 0,02242198 0,03588764 ! response to retinoic acid GO:0032526 25 18 0,000 0,02242198 0,03586269 ! pigmentation during development GO:0048066 31 18 0,000 0,02242198 0,03583777 ! central nervous system neuron development GO:0021954 30 18 0,000 0,02242198 0,03581288 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,02242198 0,03578803 ! fucose metabolic process GO:0006004 26 18 0,000 0,02242198 0,03576321 ! response to fungus GO:0009620 19 18 0,000 0,02242198 0,03573842 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,02242198 0,03571367 ! heart process GO:0003015 27 18 0,000 0,02242198 0,03568896 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,02242198 0,03566428 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,02242198 0,03563963 ! somitogenesis GO:0001756 24 18 0,000 0,02242198 0,03561502 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,02242198 0,03559044 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,02242198 0,03556589 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,02242198 0,03554138 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,02242198 0,0355169 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,02242198 0,03549246 ! vitamin transport GO:0051180 24 18 0,000 0,02242198 0,03546805 ! hormone transport GO:0009914 27 18 0,000 0,02242198 0,03544367 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,02242198 0,03541933 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,02242198 0,03539502 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,02242198 0,03537074 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,02242198 0,0353465 ! cell-cell recognition GO:0009988 20 18 0,000 0,02242198 0,03532229 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,02242198 0,03529811 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,02242198 0,03527397 ! regulation of glucose import GO:0046324 21 18 0,000 0,02242198 0,03524986 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,02242198 0,03522578 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,02242198 0,03520174 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,02242198 0,03517772 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,02242198 0,03515375 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,02365346 0,03705924 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,02365346 0,03703402 ! positive regulation of ossification GO:0045778 30 19 0,000 0,02365346 0,03700882 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,02365346 0,03698366 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,02365346 0,03695854 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,02365346 0,03693345 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,02365346 0,03690839 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,02365346 0,03688337 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,02365346 0,03685838 ! regeneration GO:0031099 32 19 0,000 0,02365346 0,03683342 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,02365346 0,0368085 ! response to alkaloid GO:0043279 32 19 0,000 0,02365346 0,03678362 ! sensory perception of taste GO:0050909 23 19 0,000 0,02365346 0,03675876 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,02365346 0,03673394 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 0,000 0,02365346 0,03670916 ! smooth muscle contraction GO:0006939 36 19 0,000 0,02365346 0,0366844 ! peroxisome organization GO:0007031 29 19 0,000 0,02365346 0,03665968 ! digestive system process GO:0022600 30 19 0,000 0,02365346 0,036635 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,02365346 0,03661034 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,02365346 0,03658572 ! response to vitamin A GO:0033189 26 19 0,000 0,02365346 0,03656113 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,02365346 0,03653658 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,02365346 0,03651206 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,02365346 0,03648757 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,02365346 0,03646312 ! response to starvation GO:0042594 30 19 0,000 0,02365346 0,03643869 ! sex determination GO:0007530 29 19 0,000 0,02365346 0,0364143 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,02365346 0,03638995 ! plasma membrane fusion GO:0045026 23 19 0,000 0,02365346 0,03636562 ! cytolysis GO:0019835 20 19 0,000 0,02365346 0,03634133 ! renal system process GO:0003014 35 19 0,000 0,02365346 0,03631707 ! vasodilation GO:0042311 33 19 0,000 0,02365346 0,03629284 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,02365346 0,03626865 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,02365346 0,03624448 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,02365346 0,03622035 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,02365346 0,03619625 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,02365346 0,03617219 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,02365346 0,03614815 ! sarcomere organization GO:0045214 23 19 0,000 0,02365346 0,03612415 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,02365346 0,03610018 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,02365346 0,03607624 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,02365346 0,03605233 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,02365346 0,03602846 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,02365346 0,03600461 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,02365346 0,0359808 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,02365346 0,03595702 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,02365346 0,03593327 ! protein stabilization GO:0050821 26 19 0,000 0,02365346 0,03590955 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,02488347 0,03775197 ! iron ion transport GO:0006826 37 20 0,000 0,02488347 0,03772708 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,02488347 0,03770223 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,02488347 0,03767741 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,02488347 0,03765262 ! response to vitamin GO:0033273 29 20 0,000 0,02488347 0,03762787 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,02488347 0,03760314 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,02488347 0,03757845 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,02488347 0,0375538 ! spinal cord development GO:0021510 31 20 0,000 0,02488347 0,03752917 ! response to ethanol GO:0045471 37 20 0,000 0,02488347 0,03750458 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,02488347 0,03748002 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 0,000 0,02488347 0,03745549 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,02488347 0,03743099 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,02488347 0,03740653 ! chromosome condensation GO:0030261 31 20 0,000 0,02488347 0,03738209 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,02488347 0,03735769 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,02488347 0,03733332 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,02488347 0,03730899 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,02488347 0,03728468 ! pallium development GO:0021543 38 20 0,000 0,02488347 0,03726041 ! DNA modification GO:0006304 28 20 0,000 0,02488347 0,03723617 ! collagen fibril organization GO:0030199 45 20 0,000 0,02488347 0,03721195 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,02488347 0,03718778 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,02488347 0,03716363 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,02488347 0,03713951 ! positive regulation of B cell activation GO:0050871 31 20 0,000 0,02488347 0,03711543 ! collagen catabolic process GO:0030574 25 20 0,000 0,02488347 0,03709137 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,02488347 0,03706735 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,02488347 0,03704336 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,02488347 0,0370194 ! alditol metabolic process GO:0019400 24 20 0,000 0,02488347 0,03699547 ! actin filament-based movement GO:0030048 34 20 0,000 0,02488347 0,03697157 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,026112 0,03877185 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,026112 0,03874684 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,026112 0,03872186 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,026112 0,03869691 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 0,000 0,026112 0,03867199 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,026112 0,03864711 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,026112 0,03862225 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,026112 0,03859743 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,026112 0,03857264 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,026112 0,03854788 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,026112 0,03852316 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,026112 0,03849846 ! protein amino acid acylation GO:0043543 37 21 0,000 0,026112 0,0384738 ! vesicle docking GO:0048278 27 21 0,000 0,026112 0,03844917 ! phototransduction GO:0007602 25 21 0,000 0,026112 0,03842457 ! dendrite development GO:0016358 35 21 0,000 0,026112 0,0384 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,026112 0,03837546 ! ovarian follicle development GO:0001541 30 21 0,000 0,026112 0,03835096 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,026112 0,03832648 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,026112 0,03830204 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,026112 0,03827763 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,026112 0,03825325 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,026112 0,0382289 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,026112 0,03820458 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,026112 0,03818029 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,026112 0,03815604 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,026112 0,03813181 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,026112 0,03810762 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,026112 0,03808345 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,026112 0,03805932 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,026112 0,03803521 ! fatty acid transport GO:0015908 30 21 0,000 0,026112 0,03801114 ! immunoglobulin production GO:0002377 33 21 0,000 0,026112 0,0379871 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,026112 0,03796309 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,026112 0,0379391 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,026112 0,03791515 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,026112 0,03789123 ! cellular response to extracellular stimulus GO:0031668 32 21 0,000 0,026112 0,03786734 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,026112 0,03784348 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,026112 0,03781965 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,026112 0,03779585 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,026112 0,03777208 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,026112 0,03774834 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,026112 0,03772462 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,026112 0,03770094 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,026112 0,03767729 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,02733905 0,03942308 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,02733905 0,03939838 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,02733905 0,03937371 ! viral genome replication GO:0019079 29 22 0,000 0,02733905 0,03934907 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,02733905 0,03932446 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,02733905 0,03929989 ! leukocyte adhesion GO:0007159 38 22 0,000 0,02733905 0,03927534 ! molting cycle process GO:0022404 40 22 0,000 0,02733905 0,03925082 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,02733905 0,03922634 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,02733905 0,03920188 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,02733905 0,03917746 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,02733905 0,03915306 ! vasculogenesis GO:0001570 33 22 0,000 0,02733905 0,0391287 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,02733905 0,03910436 GO:0051297|centrosome organization, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,02733905 0,03908006 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,02733905 0,03905579 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,02733905 0,03903154 ! lysosome organization GO:0007040 37 22 0,000 0,02733905 0,03900733 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,02733905 0,03898315 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,02733905 0,038959 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,02733905 0,03893487 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,02733905 0,03891078 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,02733905 0,03888672 ! membrane depolarization GO:0051899 35 22 0,000 0,02733905 0,03886268 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,02733905 0,03883868 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,02733905 0,0388147 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,02733905 0,03879076 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,02733905 0,03876684 ! blastocyst development GO:0001824 37 22 0,000 0,02733905 0,03874296 ! neural tube closure GO:0001843 33 22 0,000 0,02733905 0,0387191 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,02733905 0,03869527 ! protein tetramerization GO:0051262 39 22 0,000 0,02733905 0,03867148 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,02856463 0,04038023 ! neuron fate commitment GO:0048663 32 23 0,000 0,02856463 0,04035543 ! embryonic pattern specification GO:0009880 31 23 0,000 0,02856463 0,04033066 ! myelination GO:0042552 35 23 0,000 0,02856463 0,04030591 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,02856463 0,0402812 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,02856463 0,04025652 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,02856463 0,04023187 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,02856463 0,04020725 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,02856463 0,04018266 ! vesicle targeting GO:0006903 32 23 0,000 0,02856463 0,04015809 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,02856463 0,04013356 ! osteoblast differentiation GO:0001649 40 23 0,000 0,02856463 0,04010906 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,02856463 0,04008459 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,02856463 0,04006015 ! interaction with host GO:0051701 37 23 0,000 0,02856463 0,04003574 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,02856463 0,04001135 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,02856463 0,039987 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,02856463 0,03996268 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,02856463 0,03993838 ! negative regulation of phosphorylation GO:0042326 41 23 0,000 0,02856463 0,03991412 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,02856463 0,03988989 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,02856463 0,03986568 ! cell fate determination GO:0001709 45 23 0,000 0,02856463 0,0398415 ! pentose metabolic process GO:0019321 31 23 0,000 0,02856463 0,03981736 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,02856463 0,03979324 ! spermatid development GO:0007286 33 23 0,000 0,02856463 0,03976915 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,02856463 0,03974509 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,02856463 0,03972106 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,02856463 0,03969706 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,02856463 0,03967309 ! telomere organization GO:0032200 32 23 0,000 0,02856463 0,03964915 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,02856463 0,03962524 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,02856463 0,03960135 ! regulation of amine transport GO:0051952 38 23 0,000 0,02856463 0,03957749 ! liver development GO:0001889 40 23 0,000 0,02856463 0,03955367 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,02978873 0,04122387 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,02978873 0,04119908 ! initiation of viral infection GO:0019059 42 24 0,000 0,02978873 0,04117432 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,02978873 0,04114959 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,02978873 0,04112489 ! superoxide metabolic process GO:0006801 32 24 0,000 0,02978873 0,04110022 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,02978873 0,04107558 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! insulin receptor signaling pathway GO:0008286 40 24 0,000 0,02978873 0,04105097 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,02978873 0,04102639 ! sperm motility GO:0030317 27 24 0,000 0,02978873 0,04100184 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,02978873 0,04097732 ! vacuole organization GO:0007033 39 24 0,000 0,02978873 0,04095282 ! receptor metabolic process GO:0043112 37 24 0,000 0,02978873 0,04092836 ! neural crest cell development GO:0014032 39 24 0,000 0,02978873 0,04090392 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,02978873 0,04087952 ! primary neural tube formation GO:0014020 35 24 0,000 0,02978873 0,04085514 ! negative regulation of cell development GO:0010721 56 24 0,000 0,02978873 0,04083079 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,02978873 0,04080648 ! base-excision repair GO:0006284 31 24 0,000 0,02978873 0,04078219 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,02978873 0,04075793 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,02978873 0,04073369 ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,02978873 0,04070949 ! glutathione metabolic process GO:0006749 29 24 0,000 0,02978873 0,04068532 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,02978873 0,04066117 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,02978873 0,04063705 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,02978873 0,04061297 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,03101136 0,04225481 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,03101136 0,04222979 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,03101136 0,0422048 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,03101136 0,04217985 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,03101136 0,04215492 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,03101136 0,04213002 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 0,000 0,03101136 0,04210515 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,03101136 0,04208031 ! peptide transport GO:0015833 43 25 0,000 0,03101136 0,04205549 ! male gonad development GO:0008584 33 25 0,000 0,03101136 0,04203071 ! iron ion homeostasis GO:0055072 39 25 0,000 0,03101136 0,04200596 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,03101136 0,04198124 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,03101136 0,04195654 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,03101136 0,04193187 ! phospholipid transport GO:0015914 35 25 0,000 0,03101136 0,04190724 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,03101136 0,04188263 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,03101136 0,04185805 ! detection of light stimulus GO:0009583 30 25 0,000 0,03101136 0,0418335 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,03101136 0,04180898 GO:0045840|positive regulation of mitosis, ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,03101136 0,04178449 ! leukocyte proliferation GO:0070661 39 25 0,000 0,03101136 0,04176002 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,03101136 0,04173559 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,03223251 0,04335367 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,03223251 0,04332834 ! translational initiation GO:0006413 43 26 0,000 0,03223251 0,04330303 ! regulation of pH GO:0006885 36 26 0,000 0,03223251 0,04327775 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 0,000 0,03223251 0,0432525 ! circadian rhythm GO:0007623 42 26 0,000 0,03223251 0,04322728 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,03223251 0,04320209 ! post-embryonic development GO:0009791 42 26 0,000 0,03223251 0,04317693 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,03223251 0,04315179 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,03223251 0,04312669 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,03223251 0,04310162 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,03223251 0,04307657 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,03223251 0,04305156 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,03223251 0,04302657 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,03223251 0,04300161 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,0334522 0,04460294 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,0334522 0,04457709 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,0334522 0,04455128 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,0334522 0,0445255 ! membrane docking GO:0022406 39 27 0,000 0,0334522 0,04449975 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,0334522 0,04447403 ! catechol metabolic process GO:0009712 43 27 0,000 0,0334522 0,04444833 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,0334522 0,04442267 ! acute-phase response GO:0006953 42 27 0,000 0,0334522 0,04439704 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,0334522 0,04437143 ! myofibril assembly GO:0030239 36 27 0,000 0,0334522 0,04434586 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,0334522 0,04432031 ! response to ionizing radiation GO:0010212 47 27 0,000 0,0334522 0,0442948 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,0334522 0,04426931 ! natural killer cell activation GO:0030101 35 27 0,000 0,0334522 0,04424386 ! lipid oxidation GO:0034440 38 27 0,000 0,0334522 0,04421843 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,0334522 0,04419303 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,0334522 0,04416766 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,0334522 0,04414232 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,0334522 0,04411701 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of protein transport GO:0051224 49 27 0,000 0,0334522 0,04409173 ! gene silencing GO:0016458 41 27 0,000 0,0334522 0,04406648 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,03467042 0,04564509 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,03467042 0,04561898 ! phenol metabolic process GO:0018958 44 28 0,000 0,03467042 0,0455929 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,03467042 0,04556684 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,03467042 0,04554082 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,03467042 0,04551483 ! cell junction assembly GO:0034329 56 28 0,000 0,03467042 0,04548886 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,03467042 0,04546293 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,03467042 0,04543702 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,03467042 0,04541115 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,03467042 0,0453853 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,03467042 0,04535948 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,03467042 0,0453337 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,03467042 0,04530794 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,03467042 0,04528221 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,03467042 0,04525651 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,03467042 0,04523084 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,03467042 0,0452052 ! mesoderm formation GO:0001707 46 28 0,000 0,03467042 0,04517959 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,03467042 0,04515401 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,03467042 0,04512845 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,03467042 0,04510293 ! ensheathment of neurons GO:0007272 43 28 0,000 0,03467042 0,04507743 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,03467042 0,04505196 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,03467042 0,04502652 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,03467042 0,04500111 ! neural tube formation GO:0001841 41 28 0,000 0,03467042 0,04497573 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,03467042 0,04495038 ! placenta development GO:0001890 37 28 0,000 0,03467042 0,04492506 ! regulation of B cell activation GO:0050864 42 28 0,000 0,03467042 0,04489976 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,03588718 0,04644936 ! regulation of innate immune response GO:0045088 38 29 0,000 0,03588718 0,04642324 ! ovulation cycle process GO:0022602 41 29 0,000 0,03588718 0,04639714 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,03588718 0,04637107 ! protein targeting to membrane GO:0006612 53 29 0,000 0,03588718 0,04634504 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,03588718 0,04631903 ! mismatch repair GO:0006298 34 29 0,000 0,03588718 0,04629305 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,03588718 0,0462671 ! muscle cell development GO:0055001 38 29 0,000 0,03588718 0,04624118 ! formation of primary germ layer GO:0001704 48 29 0,000 0,03588718 0,04621529 ! telencephalon development GO:0021537 52 29 0,000 0,03588718 0,04618943 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,03588718 0,0461636 ! eye morphogenesis GO:0048592 51 29 0,000 0,03588718 0,04613779 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,03588718 0,04611202 ! tissue homeostasis GO:0001894 42 29 0,000 0,03588718 0,04608627 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,03710247 0,04762036 ! collagen metabolic process GO:0032963 40 30 0,000 0,03710247 0,0475938 ! organic anion transport GO:0015711 51 30 0,000 0,03710247 0,04756727 ! cholesterol transport GO:0030301 46 30 0,000 0,03710247 0,04754077 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,03710247 0,0475143 ! spliceosome assembly GO:0000245 49 30 0,000 0,03710247 0,04748786 ! spindle organization GO:0007051 37 30 0,000 0,03710247 0,04746145 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,03710247 0,04743507 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,03710247 0,04740871 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,03710247 0,04738239 ! ceramide metabolic process GO:0006672 43 30 0,000 0,03710247 0,04735609 ! ovulation cycle GO:0042698 43 30 0,000 0,03710247 0,04732983 ! hindbrain development GO:0030902 45 30 0,000 0,03710247 0,04730359 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,03710247 0,04727739 ! adult locomotory behavior GO:0008344 47 30 0,000 0,03710247 0,04725121 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,03710247 0,04722506 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,03710247 0,04719894 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,03710247 0,04717285 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,03710247 0,04714679 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,0383163 0,04866234 ! negative regulation of secretion GO:0051048 49 31 0,000 0,0383163 0,04863548 ! mammary gland development GO:0030879 57 31 0,000 0,0383163 0,04860865 ! glial cell differentiation GO:0010001 55 31 0,000 0,0383163 0,04858186 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,0383163 0,04855509 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,0383163 0,04852835 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,0383163 0,04850165 ! odontogenesis GO:0042476 50 31 0,000 0,0383163 0,04847497 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,0383163 0,04844832 ! segmentation GO:0035282 41 31 0,000 0,0383163 0,0484217 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,0383163 0,04839511 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,0383163 0,04836855 ! metanephros development GO:0001656 58 31 0,000 0,0383163 0,04834201 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,0383163 0,04831551 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,0383163 0,04828904 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,0383163 0,04826259 ! cell fate specification GO:0001708 37 31 0,000 0,0383163 0,04823617 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,0383163 0,04820979 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,0383163 0,04818343 ! RNA modification GO:0009451 40 31 0,000 0,0383163 0,0481571 ! regulation of muscle development GO:0048634 48 32 0,000 0,03952867 0,04965371 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,03952867 0,0496266 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,03952867 0,04959953 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,03952867 0,04957248 ! meiosis I GO:0007127 52 32 0,000 0,03952867 0,04954547 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,03952867 0,04951848 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,03952867 0,04949153 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,03952867 0,0494646 ! peripheral nervous system development GO:0007422 53 32 0,000 0,03952867 0,0494377 ! regulation of protein stability GO:0031647 48 32 0,000 0,03952867 0,04941084 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,03952867 0,049384 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,03952867 0,04935719 ! cytokine production GO:0001816 44 32 0,000 0,03952867 0,04933041 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,03952867 0,04930365 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,03952867 0,04927693 ! vesicle localization GO:0051648 47 32 0,000 0,03952867 0,04925024 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,04073958 0,05073147 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,04073958 0,05070402 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,04073958 0,0506766 ! sister chromatid segregation GO:0000819 46 33 0,000 0,04073958 0,0506492 ! ear morphogenesis GO:0042471 42 33 0,000 0,04073958 0,05062184 ! actomyosin structure organization GO:0031032 43 33 0,000 0,04073958 0,05059451 ! cell junction organization GO:0034330 63 33 0,000 0,04073958 0,0505672 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,04073958 0,05053993 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,04073958 0,05051268 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,04073958 0,05048547 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 0,000 0,04073958 0,05045828 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,04073958 0,05043112 ! female gonad development GO:0008585 49 33 0,000 0,04073958 0,050404 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,04073958 0,0503769 ! positive regulation of cell development GO:0010720 54 33 0,000 0,04073958 0,05034983 ! lipid homeostasis GO:0055088 55 33 0,000 0,04073958 0,05032279 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,04073958 0,05029577 ! regulation of proteolysis GO:0030162 50 33 0,000 0,04073958 0,05026879 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,04073958 0,05024184 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,04073958 0,05021491 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,04073958 0,05018802 ! cytokinesis GO:0000910 52 33 0,000 0,04073958 0,05016115 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,04073958 0,05013431 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,04194903 0,05159506 ! mRNA catabolic process GO:0006402 48 34 0,000 0,04194903 0,05156749 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,04194903 0,05153994 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,04194903 0,05151242 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,04194903 0,05148494 ! feeding behavior GO:0007631 45 34 0,000 0,04194903 0,05145748 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,04194903 0,05143005 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,04194903 0,05140265 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,04194903 0,05137528 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,04194903 0,05134793 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,04194903 0,05132062 ! neuron migration GO:0001764 46 34 0,000 0,04194903 0,05129334 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,04194903 0,05126608 ! female gamete generation GO:0007292 43 34 0,000 0,04194903 0,05123886 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,04194903 0,05121166 ! polyol metabolic process GO:0019751 44 34 0,000 0,04194903 0,05118449 ! aerobic respiration GO:0009060 47 34 0,000 0,04194903 0,05115735 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,04194903 0,05113024 ! cellular response to insulin stimulus GO:0032869 52 34 0,000 0,04194903 0,05110316 ! embryonic organ development GO:0048568 45 34 0,000 0,04194903 0,05107611 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,04194903 0,05104908 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,04315703 0,05249136 ! Notch signaling pathway GO:0007219 56 35 0,000 0,04315703 0,05246362 ! regulation of intracellular protein transport GO:0033157 59 35 0,000 0,04315703 0,0524359 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,04315703 0,05240822 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,04315703 0,05238056 GO:0032313|regulation of Rab GTPase activity, ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,04315703 0,05235293 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,04315703 0,05232533 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,04315703 0,05229777 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,04315703 0,05227023 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,04315703 0,05224272 ! glycogen metabolic process GO:0005977 48 35 0,000 0,04315703 0,05221523 ! pigment metabolic process GO:0042440 61 35 0,000 0,04315703 0,05218778 ! positive regulation of leukocyte proliferation GO:0070665 50 35 0,000 0,04315703 0,05216036 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! protein homooligomerization GO:0051260 52 35 0,000 0,04315703 0,05213296 ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,04436357 0,05356231 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 0,000 0,04436357 0,05353421 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,04436357 0,05350614 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,04436357 0,0534781 ! negative regulation of binding GO:0051100 58 36 0,000 0,04436357 0,05345008 ! organic ether metabolic process GO:0018904 46 36 0,000 0,04436357 0,0534221 ! tissue remodeling GO:0048771 62 36 0,000 0,04436357 0,05339414 ! neural tube development GO:0021915 50 36 0,000 0,04436357 0,05336622 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,04436357 0,05333832 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,04436357 0,05331045 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,04436357 0,05328261 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,04436357 0,05325481 ! glucan metabolic process GO:0044042 49 36 0,000 0,04436357 0,05322703 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,04556866 0,05464438 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,04556866 0,0546159 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,04556866 0,05458746 ! ion transmembrane transport GO:0034220 56 37 0,000 0,04556866 0,05455904 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,04556866 0,05453065 ! regulation of protein secretion GO:0050708 51 37 0,000 0,04556866 0,0545023 ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,04556866 0,05447397 ! gliogenesis GO:0042063 71 38 0,000 0,0467723 0,05588378 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,0467723 0,05585477 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,0467723 0,05582578 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,0467723 0,05579683 ! mesenchymal cell development GO:0014031 64 38 0,000 0,0467723 0,0557679 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 0,000 0,0467723 0,05573901 ! maintenance of location in cell GO:0051651 69 38 0,000 0,0467723 0,05571014 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,04797449 0,05711249 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,04797449 0,05708294 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,04797449 0,05705342 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,04797449 0,05702394 ! regulation of epithelial cell proliferation GO:0050678 71 39 0,000 0,04797449 0,05699449 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,04797449 0,05696506 ! male sex differentiation GO:0046661 53 39 0,000 0,04797449 0,05693567 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,04797449 0,0569063 ! chromatin remodeling GO:0006338 68 39 0,000 0,04797449 0,05687697 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,04797449 0,05684767 ! JNK cascade GO:0007254 54 39 0,000 0,04797449 0,0568184 ! developmental growth GO:0048589 62 39 0,000 0,04797449 0,05678915 ! synapse organization GO:0050808 55 39 0,000 0,04797449 0,05675994 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,04917523 0,05815066 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,04917523 0,05812078 ! regulation of tube size GO:0035150 60 40 0,000 0,04917523 0,05809093 GO:0050880|regulation of blood vessel size, ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,04917523 0,0580611 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,04917523 0,05803131 ! peptide metabolic process GO:0006518 56 40 0,000 0,04917523 0,05800156 ! induction of apoptosis by intracellular signals GO:0008629 67 40 0,000 0,04917523 0,05797183 ! inner ear development GO:0048839 57 40 0,000 0,04917523 0,05794213 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,04917523 0,05791246 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,04917523 0,05788282 ! double-strand break repair GO:0006302 67 40 0,000 0,04917523 0,05785321 ! B cell differentiation GO:0030183 62 40 0,000 0,04917523 0,05782364 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,04917523 0,05779409 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,04917523 0,05776457 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,04917523 0,05773509 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,05037453 0,05911297 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,05037453 0,05908282 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,05037453 0,05905271 ! glucose transport GO:0015758 52 41 0,000 0,05037453 0,05902263 ! endosome transport GO:0016197 71 41 0,000 0,05037453 0,05899257 ! striated muscle contraction GO:0006941 62 41 0,000 0,05037453 0,05896255 ! positive regulation of DNA binding GO:0043388 57 41 0,000 0,05037453 0,05893256 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,05037453 0,0589026 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,05037453 0,05887267 ! biopolymer methylation GO:0043414 62 41 0,000 0,05037453 0,05884277 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,05037453 0,0588129 ! mitochondrial transport GO:0006839 60 42 0,000 0,05157238 0,06018086 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,05157238 0,06015034 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 0,000 0,05157238 0,06011986 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,05157238 0,0600894 ! cellular component disassembly GO:0022411 64 42 0,000 0,05157238 0,06005898 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,05157238 0,06002858 ! hexose transport GO:0008645 54 42 0,000 0,05157238 0,05999822 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,05157238 0,05996789 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,05157238 0,05993758 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,05157238 0,05990731 ! excretion GO:0007588 63 42 0,000 0,05157238 0,05987707 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,05157238 0,05984686 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,05157238 0,05981668 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,05157238 0,05978653 ! regulation of cell shape GO:0008360 78 42 0,000 0,05157238 0,05975641 ! positive regulation of binding GO:0051099 59 43 0,000 0,05276879 0,0611119 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,05276879 0,06108114 ! leukocyte migration GO:0050900 60 43 0,000 0,05276879 0,06105041 ! neuromuscular process GO:0050905 79 43 0,000 0,05276879 0,06101972 ! activation of caspase activity GO:0006919 65 43 0,000 0,05276879 0,06098906 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,05276879 0,06095843 ! tRNA processing GO:0008033 49 43 0,000 0,05276879 0,06092782 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,05276879 0,06089725 ! vesicle organization GO:0016050 79 43 0,000 0,05276879 0,06086671 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,05276879 0,0608362 ! methylation GO:0032259 64 43 0,000 0,05276879 0,06080572 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,05396376 0,06215156 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,05396376 0,06212045 ! glycolysis GO:0006096 53 44 0,000 0,05396376 0,06208937 ! regulation of action potential GO:0001508 71 44 0,000 0,05396376 0,06205833 ! regulation of ion transport GO:0043269 57 44 0,000 0,05396376 0,06202731 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,05396376 0,06199633 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,05396376 0,06196538 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,05396376 0,06193446 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,05396376 0,06190357 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,05396376 0,06187271 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,05396376 0,06184188 ! regulation of mast cell proliferation GO:0070666 64 44 0,000 0,05396376 0,06181108 ! RNA catabolic process GO:0006401 64 45 0,000 0,05515729 0,06314673 ! positive regulation of defense response GO:0031349 59 45 0,000 0,05515729 0,06311531 ! regulation of translational initiation GO:0006446 64 45 0,000 0,05515729 0,06308393 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,05515729 0,06305257 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,05515729 0,06302125 ! cell recognition GO:0008037 58 45 0,000 0,05515729 0,06298996 ! cell maturation GO:0048469 60 45 0,000 0,05515729 0,0629587 ! protein amino acid autophosphorylation GO:0046777 80 45 0,000 0,05515729 0,06292747 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,05634939 0,06425562 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,05634939 0,06422378 ! cell redox homeostasis GO:0045454 63 46 0,000 0,05634939 0,06419197 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,05634939 0,06416019 ! regulation of ossification GO:0030278 71 46 0,000 0,05634939 0,06412845 ! histone modification GO:0016570 68 46 0,000 0,05634939 0,06409673 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,05634939 0,06406505 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,05754005 0,06538642 ! viral infectious cycle GO:0019058 71 47 0,000 0,05754005 0,06535413 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,05754005 0,06532187 ! endocrine system development GO:0035270 83 47 0,000 0,05754005 0,06528964 ! covalent chromatin modification GO:0016569 75 47 0,000 0,05754005 0,06525745 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,05754005 0,06522529 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,05754005 0,06519316 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,05754005 0,06516106 ! regulation of leukocyte proliferation GO:0070663 71 47 0,000 0,05754005 0,06512899 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of protein polymerization GO:0032271 71 47 0,000 0,05754005 0,06509695 ! chloride transport GO:0006821 67 48 0,000 0,05872927 0,0664097 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,05872927 0,06637706 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 0,000 0,05872927 0,06634446 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,05872927 0,06631189 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,05872927 0,06627935 ! gastrulation GO:0007369 73 48 0,000 0,05872927 0,06624685 ! heart morphogenesis GO:0003007 65 48 0,000 0,05872927 0,06621437 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,05872927 0,06618193 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,05872927 0,06614952 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,05872927 0,06611714 ! regulation of endocytosis GO:0030100 63 48 0,000 0,05872927 0,0660848 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,05872927 0,06605248 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,05991706 0,06735545 ! sensory perception of smell GO:0007608 61 49 0,000 0,05991706 0,06732254 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,05991706 0,06728967 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,05991706 0,06725683 ! RNA elongation GO:0006354 62 49 0,000 0,05991706 0,06722402 ! regulation of intracellular transport GO:0032386 78 49 0,000 0,05991706 0,06719124 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,05991706 0,0671585 ! germ cell development GO:0007281 68 49 0,000 0,05991706 0,06712579 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,05991706 0,06709311 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,05991706 0,06706046 ! cartilage development GO:0051216 70 49 0,000 0,05991706 0,06702784 ! maintenance of location GO:0051235 84 49 0,000 0,05991706 0,06699526 ! regulation of actin filament length GO:0030832 72 50 0,000 0,06110342 0,06828857 ! ear development GO:0043583 72 50 0,000 0,06110342 0,0682554 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,06110342 0,06822227 ! membrane fusion GO:0006944 80 50 0,000 0,06110342 0,06818917 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,06110342 0,0681561 ! lipid modification GO:0030258 73 50 0,000 0,06110342 0,06812306 ! positive regulation of growth GO:0045927 67 50 0,000 0,06110342 0,06809005 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,06110342 0,06805708 ! proton transport GO:0015992 75 50 0,000 0,06110342 0,06802414 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,06110342 0,06799123 ! positive regulation of secretion GO:0051047 71 51 0,000 0,06228835 0,06927622 ! hydrogen transport GO:0006818 77 51 0,000 0,06228835 0,06924273 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,06228835 0,06920928 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 0,000 0,06228835 0,06917586 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,06228835 0,06914248 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,06228835 0,06910912 ! adult behavior GO:0030534 80 51 0,000 0,06228835 0,0690758 ! transition metal ion transport GO:0000041 74 52 0,000 0,06347186 0,07035435 ! regulation of cellular component size GO:0032535 74 52 0,000 0,06347186 0,07032046 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,06347186 0,0702866 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,06347186 0,07025278 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,06347186 0,07021899 ! establishment of organelle localization GO:0051656 85 52 0,000 0,06347186 0,07018523 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,06465394 0,07145798 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,06465394 0,07142366 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,06465394 0,07138937 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,06465394 0,07135511 ! kidney development GO:0001822 90 53 0,000 0,06465394 0,07132089 ! single fertilization GO:0007338 59 53 0,000 0,06465394 0,0712867 ! amino acid transport GO:0006865 84 54 0,000 0,06583459 0,07255369 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,06583459 0,07251894 ! glucose catabolic process GO:0006007 66 54 0,000 0,06583459 0,07248423 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,06583459 0,07244955 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,06583459 0,0724149 ! DNA catabolic process GO:0006308 67 54 0,000 0,06583459 0,07238028 ! detection of external stimulus GO:0009581 66 54 0,000 0,06583459 0,0723457 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,06583459 0,07231115 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,06583459 0,07227664 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,06583459 0,07224215 ! exocytosis GO:0006887 74 55 0,000 0,06701382 0,07350109 ! mesoderm development GO:0007498 76 55 0,000 0,06701382 0,07346606 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,06701382 0,07343106 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,06701382 0,07339609 ! DNA damage response, signal transduction GO:0042770 96 56 0,000 0,06819163 0,07465052 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,06819163 0,07461501 ! negative regulation of protein kinase activity GO:0006469 99 57 0,000 0,06936802 0,07586612 ! carbohydrate transport GO:0008643 74 57 0,000 0,06936802 0,07583006 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,06936802 0,07579404 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 0,000 0,06936802 0,07575805 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,06936802 0,07572209 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,06936802 0,07568617 ! camera-type eye development GO:0043010 88 57 0,000 0,06936802 0,07565028 ! secondary metabolic process GO:0019748 84 57 0,000 0,06936802 0,07561443 ! developmental maturation GO:0021700 75 57 0,000 0,06936802 0,07557861 ! gonad development GO:0008406 79 57 0,000 0,06936802 0,07554283 ! negative regulation of kinase activity GO:0033673 100 58 0,000 0,07054299 0,07678603 ! viral reproductive process GO:0022415 87 58 0,000 0,07054299 0,07674971 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,07054299 0,07671342 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,07054299 0,07667717 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,07054299 0,07664095 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,07171655 0,07787916 ! lung development GO:0030324 94 59 0,000 0,07171655 0,07784241 ! actin filament organization GO:0007015 95 59 0,000 0,07171655 0,07780569 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,07171655 0,07776901 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,07171655 0,07773236 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,07288869 0,07896561 ! phosphoinositide metabolic process GO:0030384 87 60 0,000 0,07288869 0,07892843 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,07288869 0,07889129 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,07288869 0,07885418 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,07288869 0,07881711 ! regulation of heart contraction GO:0008016 91 60 0,000 0,07288869 0,07878007 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,07288869 0,07874307 ! fertilization GO:0009566 68 60 0,000 0,07288869 0,0787061 ! regulation of homeostatic process GO:0032844 105 60 0,000 0,07288869 0,07866917 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,07405942 0,07989525 ! meiosis GO:0007126 96 61 0,000 0,07405942 0,07985779 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 114 61 0,000 0,07405942 0,07982037 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,07405942 0,07978298 ! urogenital system development GO:0001655 101 61 0,000 0,07405942 0,07974563 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,07405942 0,07970832 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,07405942 0,07967103 ! extracellular matrix organization GO:0030198 103 61 0,000 0,07405942 0,07963379 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,07405942 0,07959658 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! negative regulation of transferase activity GO:0051348 105 61 0,000 0,07405942 0,0795594 ! amine catabolic process GO:0009310 90 62 0,000 0,07522874 0,08077783 ! neurotransmitter transport GO:0006836 81 62 0,000 0,07522874 0,08074013 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,07522874 0,08070247 ! negative regulation of cell growth GO:0030308 106 62 0,000 0,07522874 0,08066485 ! respiratory tube development GO:0030323 99 62 0,000 0,07522874 0,08062726 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,07522874 0,08058971 ! meiotic cell cycle GO:0051321 97 62 0,000 0,07522874 0,08055219 ! organelle localization GO:0051640 96 62 0,000 0,07522874 0,08051471 ! regulation of transcription factor activity GO:0051090 97 63 0,000 0,07639665 0,08172665 GO:0090046|regulation of transcription regulator activity, ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,07639665 0,08168865 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 0,000 0,07639665 0,08165069 ! viral reproduction GO:0016032 92 63 0,000 0,07639665 0,08161277 ! regulation of lipase activity GO:0060191 109 63 0,000 0,07639665 0,08157488 ! cell cycle checkpoint GO:0000075 108 64 0,000 0,07756315 0,08278202 ! negative regulation of cell size GO:0045792 108 64 0,000 0,07756315 0,08274362 ! appendage morphogenesis GO:0035107 93 64 0,000 0,07756315 0,08270526 GO:0035108|limb morphogenesis, ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,07756315 0,08266693 ! hexose catabolic process GO:0019320 82 64 0,000 0,07756315 0,08262865 ! respiratory system development GO:0060541 100 64 0,000 0,07756315 0,08259039 ! adaptive immune response GO:0002250 94 64 0,000 0,07756315 0,08255217 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 90 65 0,000 0,07872824 0,08375345 ! regulation of caspase activity GO:0043281 97 65 0,000 0,07872824 0,08371473 ! appendage development GO:0048736 94 65 0,000 0,07872824 0,08367605 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 0,000 0,07872824 0,0836374 ! defense response to bacterium GO:0042742 73 65 0,000 0,07872824 0,08359878 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,07872824 0,0835602 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,07872824 0,08352166 ! activation of immune response GO:0002253 83 65 0,000 0,07872824 0,08348315 ! protein oligomerization GO:0051259 100 65 0,000 0,07872824 0,08344468 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,07989193 0,08463908 ! antigen processing and presentation GO:0019882 96 66 0,000 0,07989193 0,08460011 ! axon guidance GO:0007411 99 66 0,000 0,07989193 0,08456118 ! regulation of immune effector process GO:0002697 101 66 0,000 0,07989193 0,08452229 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,08105422 0,08571251 ! regulation of endopeptidase activity GO:0052548 99 67 0,000 0,08105422 0,08567312 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,08105422 0,08563376 ! acute inflammatory response GO:0002526 92 68 0,000 0,0822151 0,08682036 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,0822151 0,08678051 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,0822151 0,08674071 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,0822151 0,08670094 ! rhythmic process GO:0048511 105 68 0,000 0,0822151 0,0866612 ! inorganic anion transport GO:0015698 93 68 0,000 0,0822151 0,0866215 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,08337459 0,08780291 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,08337459 0,08776273 ! response to drug GO:0042493 108 69 0,000 0,08337459 0,08772258 ! humoral immune response GO:0006959 86 70 0,000 0,08453268 0,08890039 ! eye development GO:0001654 111 70 0,000 0,08453268 0,08885976 ! amine transport GO:0015837 101 70 0,000 0,08453268 0,08881917 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,08453268 0,08877861 ! regulation of catabolic process GO:0009894 106 70 0,000 0,08453268 0,08873809 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,08568937 0,08991129 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,08568937 0,08987029 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,08568937 0,08982933 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,08568937 0,0897884 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,08568937 0,08974751 ! regulation of peptidase activity GO:0052547 106 72 0,000 0,08684466 0,09091612 ! negative regulation of organelle organization GO:0010639 115 72 0,000 0,08684466 0,09087476 ! regulation of blood pressure GO:0008217 107 73 0,000 0,08799856 0,09204033 ! tube morphogenesis GO:0035239 118 73 0,000 0,08799856 0,0919985 ! mitochondrion organization GO:0007005 104 73 0,000 0,08799856 0,0919567 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,08799856 0,09191494 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,08915107 0,09307647 ! digestion GO:0007586 97 74 0,000 0,08915107 0,09303424 ! protein import into nucleus GO:0006606 118 74 0,000 0,08915107 0,09299205 ! cellular response to hormone stimulus GO:0032870 109 74 0,000 0,08915107 0,09294989 ! positive regulation of lymphocyte activation GO:0051251 108 74 0,000 0,08915107 0,09290778 ! blood coagulation GO:0007596 116 75 0,000 0,09030219 0,09406478 GO:0050817|coagulation, ! negative regulation of growth GO:0045926 123 75 0,000 0,09030219 0,0940222 ! response to nutrient GO:0007584 104 75 0,000 0,09030219 0,09397965 ! nuclear import GO:0051170 121 75 0,000 0,09030219 0,09393715 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,09030219 0,09389468 ! amine biosynthetic process GO:0009309 97 76 0,000 0,09145192 0,09504718 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,09145192 0,09500425 ! regulation of protein transport GO:0051223 114 76 0,000 0,09145192 0,09496136 GO:0070201|regulation of establishment of protein localization, ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,09260026 0,09611038 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,09260026 0,09606703 ! regulation of DNA binding GO:0051101 119 77 0,000 0,09260026 0,09602372 ! gland development GO:0048732 148 77 0,000 0,09260026 0,09598044 ! sex differentiation GO:0007548 105 77 0,000 0,09260026 0,09593721 ! protein ubiquitination GO:0016567 125 77 0,000 0,09260026 0,09589401 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,09260026 0,09585086 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,09260026 0,09580774 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,09374722 0,09695081 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,09374722 0,09690724 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,09489279 0,09804736 ! cellular respiration GO:0045333 107 79 0,000 0,09489279 0,09800333 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,09489279 0,09795935 ! T cell activation GO:0042110 134 79 0,000 0,09489279 0,0979154 ! regulation of lyase activity GO:0051339 133 79 0,000 0,09489279 0,09787149 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,09489279 0,09782762 ! chromatin assembly GO:0031497 102 80 0,000 0,09603698 0,09896284 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,09603698 0,09891852 ! protein localization in nucleus GO:0034504 133 80 0,000 0,09603698 0,09887425 ! forebrain development GO:0030900 131 80 0,000 0,09603698 0,09883001 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,09717979 0,09996133 ! hemostasis GO:0007599 125 81 0,000 0,09717979 0,09991664 ! mRNA transport GO:0051028 121 81 0,000 0,09717979 0,099872 ! vitamin metabolic process GO:0006766 103 81 0,000 0,09717979 0,09982739 ! ossification GO:0001503 134 82 0,000 0,09832123 0,10095483 GO:0060348|bone development, ! detection of stimulus GO:0051606 108 82 0,000 0,09832123 0,10090978 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,09946128 0,10203432 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,09946128 0,10198883 ! regulation of defense response GO:0031347 117 84 0,000 0,10059996 0,10311047 ! microtubule cytoskeleton organization GO:0000226 120 84 0,000 0,10059996 0,10306454 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,10059996 0,10301866 ! sterol metabolic process GO:0016125 120 84 0,000 0,10059996 0,10297281 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,10173726 0,10409061 ! rRNA metabolic process GO:0016072 107 85 0,000 0,10173726 0,10404433 GO:0006364|rRNA processing, ! transcription initiation GO:0006352 118 85 0,000 0,10173726 0,10399809 ! anterior/posterior pattern formation GO:0009952 124 85 0,000 0,10173726 0,10395189 ! regulation of protein localization GO:0032880 132 85 0,000 0,10173726 0,10390573 ! regulation of membrane potential GO:0042391 128 85 0,000 0,10173726 0,10385961 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,10287319 0,10497264 ! nucleosome organization GO:0034728 114 87 0,000 0,10400775 0,10608329 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,10400775 0,10603627 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,10400775 0,10598929 ! skeletal muscle tissue development GO:0007519 123 87 0,000 0,10400775 0,10594235 GO:0060538|skeletal muscle organ development, ! female pregnancy GO:0007565 130 87 0,000 0,10400775 0,10589545 ! Wnt receptor signaling pathway GO:0016055 130 87 0,000 0,10400775 0,1058486 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,10514094 0,10695452 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,10514094 0,10690723 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,10514094 0,10685999 GO:0016054|organic acid catabolic process, ! protein processing GO:0016485 114 88 0,000 0,10514094 0,10681279 ! regulation of neurogenesis GO:0050767 153 89 0,000 0,10627276 0,10791494 ! reproductive developmental process GO:0003006 127 89 0,000 0,10627276 0,10786732 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,10627276 0,10781974 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,10627276 0,1077722 ! regulation of T cell activation GO:0050863 128 89 0,000 0,10627276 0,1077247 ! leukocyte differentiation GO:0002521 143 90 0,000 0,10740322 0,10882264 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,10740322 0,10877472 ! hormone metabolic process GO:0042445 121 90 0,000 0,10740322 0,10872685 ! ATP metabolic process GO:0046034 137 91 0,000 0,10853231 0,10982151 ! response to virus GO:0009615 122 91 0,000 0,10853231 0,10977322 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,10966003 0,11086509 ! glycerophospholipid metabolic process GO:0006650 130 92 0,000 0,10966003 0,11081638 ! cell fate commitment GO:0045165 141 92 0,000 0,10966003 0,11076771 ! positive regulation of immune response GO:0050778 121 92 0,000 0,10966003 0,11071908 ! DNA recombination GO:0006310 146 92 0,000 0,10966003 0,1106705 ! sulfur metabolic process GO:0006790 118 92 0,000 0,10966003 0,11062196 ! peptidyl-amino acid modification GO:0018193 147 93 0,000 0,1107864 0,11170921 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,1107864 0,11166026 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,1107864 0,11161135 ! electron transport chain GO:0022900 123 94 0,000 0,1119114 0,11269537 ! regulation of binding GO:0051098 151 95 0,000 0,11303505 0,11377707 ! carboxylic acid transport GO:0046942 147 95 0,000 0,11303505 0,1137273 GO:0015849|organic acid transport, ! in utero embryonic development GO:0001701 147 96 0,000 0,11415733 0,11480624 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,11415733 0,11475606 ! protein maturation GO:0051604 129 96 0,000 0,11415733 0,11470593 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,11527827 0,11578167 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,11527827 0,11573113 ! calcium ion transport GO:0006816 167 99 0,000 0,11751607 0,11792625 ! extracellular structure organization GO:0043062 156 99 0,000 0,11751607 0,11787482 ! protein import GO:0017038 156 99 0,000 0,11751607 0,11782344 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,11863295 0,11889141 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,11863295 0,11883963 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,11863295 0,11878789 ! divalent metal ion transport GO:0070838 171 100 0,000 0,11863295 0,1187362 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,11863295 0,11868455 ! protein localization in organelle GO:0033365 161 100 0,000 0,11863295 0,11863295