pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-b1/out-0.05-06-0.01-300-run-b1//th1-pval-1e-01-08-th2-pval-1e-02-02-th3-pval-1e-01-01-run-b1/go_data/6801-8-real-Loi_GPL96-GPL97-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 2,000 1,359E-08 3,269E-05 ! nucleoside diphosphate metabolic process GO:0009132 13 9 2,000 3,258E-08 3,919E-05 ! deoxyribonucleotide metabolic process GO:0009262 32 22 2,000 5,935E-07 4,76E-04 ! negative regulation of protein ubiquitination GO:0031397 9 5 1,000 5,571E-06 3,351E-03 ! activation of Ras GTPase activity GO:0032856 10 5 1,000 5,571E-06 2,681E-03 GO:0032862|activation of Rho GTPase activity, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 1,558E-05 6,246E-03 ! regulation of focal adhesion formation GO:0051893 22 8 1,000 1,558E-05 5,354E-03 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 1,000 2,002E-05 6,021E-03 ! regulation of phosphatase activity GO:0010921 28 10 1,000 2,501E-05 6,686E-03 ! regulation of stress fiber formation GO:0051492 30 10 1,000 2,501E-05 6,018E-03 ! positive regulation of Rho GTPase activity GO:0032321 24 10 1,000 2,501E-05 5,471E-03 ! protein oligomerization GO:0051259 139 78 2,000 2,851E-05 5,716E-03 ! regulation of actin filament bundle formation GO:0032231 33 11 1,000 3,056E-05 5,655E-03 ! positive regulation of Ras GTPase activity GO:0032320 35 13 1,000 4,329E-05 7,44E-03 ! positive regulation of GTPase activity GO:0043547 36 14 1,000 5,048E-05 8,098E-03 ! regulation of protein ubiquitination GO:0031396 25 16 1,000 6,651E-05 0,01000165 ! regulation of dephosphorylation GO:0035303 43 16 1,000 6,651E-05 9,413E-03 ! cellular response to unfolded protein GO:0034620 33 19 1,000 9,465E-05 0,01265111 GO:0030968|endoplasmic reticulum unfolded protein response, ! negative regulation of translation GO:0017148 29 20 1,000 1,051E-04 0,01331077 ! regulation of Rho GTPase activity GO:0032319 43 21 1,000 1,161E-04 0,01396982 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 1,398E-04 0,01601397 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 1,398E-04 0,01528606 GO:0010810|regulation of cell-substrate adhesion, ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 1,656E-04 0,01732158 ! fat cell differentiation GO:0045444 50 27 1,000 1,936E-04 0,01940378 ! negative regulation of protein modification process GO:0031400 60 28 1,000 2,083E-04 0,02005121 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 2,083E-04 0,01928001 ! RNA export from nucleus GO:0006405 56 37 1,000 3,656E-04 0,03257494 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 1,000 5,657E-04 0,04861164 ! response to insulin stimulus GO:0032868 95 46 1,000 5,657E-04 0,04693538 ! response to calcium ion GO:0051592 81 47 1,000 5,906E-04 0,04736535 ! positive regulation of cell cycle GO:0045787 89 48 1,000 6,16E-04 0,04780817 ! response to UV GO:0009411 104 53 1,000 7,508E-04 0,05644765 ! nuclear export GO:0051168 97 55 1,000 8,083E-04 0,05893265 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 1,000 8,679E-04 0,0614178 ! response to peptide hormone stimulus GO:0043434 122 61 1,000 9,933E-04 0,0682837 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 1,232E-03 0,08237105 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 1,269E-03 0,0824989 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 1,000 1,38E-03 0,08739663 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 1,38E-03 0,08515569 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 1,000 1,38E-03 0,08302679 ! regulation of actin cytoskeleton organization GO:0032956 149 74 1,000 1,457E-03 0,08551754 ! regulation of actin filament-based process GO:0032970 152 77 1,000 1,576E-03 0,09030986 ! positive regulation of ligase activity GO:0051351 124 77 1,000 1,576E-03 0,08820963 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 1,000 1,658E-03 0,09068726 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 1,658E-03 0,08867199 ! response to metal ion GO:0010038 140 80 1,000 1,7E-03 0,0889273 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 1,742E-03 0,08919728 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of ligase activity GO:0051340 142 84 1,000 1,872E-03 0,09383965 ! response to unfolded protein GO:0006986 131 85 1,000 1,916E-03 0,09409596 ! response to inorganic substance GO:0010035 153 86 1,000 1,961E-03 0,09436585 ! positive regulation of protein modification process GO:0031401 136 88 1,000 2,052E-03 0,09680471 ! regulation of cell adhesion GO:0030155 212 89 1,000 2,098E-03 0,09708066 ! response to protein stimulus GO:0051789 149 91 1,000 2,192E-03 0,09951046 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 2,288E-03 0,10193775 GO:0010498|proteasomal protein catabolic process, ! interphase of mitotic cell cycle GO:0051329 209 95 1,000 2,386E-03 0,10436242 ! regulation of Rho protein signal transduction GO:0035023 213 95 1,000 2,386E-03 0,10249881 ! interphase GO:0051325 213 98 1,000 2,536E-03 0,10704698 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 3,813E-03 0,15816822 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 3,813E-03 0,1554874 ! positive regulation of helicase activity GO:0051096 11 5 0,000 3,813E-03 0,15289595 ! neuron fate determination GO:0048664 7 5 0,000 3,813E-03 0,15038946 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 3,813E-03 0,14796382 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 3,813E-03 0,14561519 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 3,813E-03 0,14333995 ! polyol transport GO:0015791 12 5 0,000 3,813E-03 0,14113472 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 3,813E-03 0,13899631 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 3,813E-03 0,13692174 ! response to superoxide GO:0000303 10 5 0,000 3,813E-03 0,13490819 ! negative regulation of bone resorption GO:0045779 10 5 0,000 3,813E-03 0,132953 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 3,813E-03 0,13105367 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 3,813E-03 0,12920784 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 3,813E-03 0,12741329 ! female meiosis GO:0007143 7 5 0,000 3,813E-03 0,1256679 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 3,813E-03 0,12396969 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 3,813E-03 0,12231676 ! cobalt ion transport GO:0006824 11 5 0,000 3,813E-03 0,12070733 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 3,813E-03 0,1191397 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 3,813E-03 0,11761227 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 3,813E-03 0,1161235 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 3,813E-03 0,11467196 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 3,813E-03 0,11325626 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 3,813E-03 0,11187508 ! embryonic camera-type eye development GO:0031076 10 5 0,000 3,813E-03 0,11052719 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 3,813E-03 0,10921139 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 3,813E-03 0,10792655 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 3,813E-03 0,10667159 ! adaptation of signaling pathway GO:0022401 7 5 0,000 3,813E-03 0,10544548 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 3,813E-03 0,10424724 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 3,813E-03 0,10307592 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 3,813E-03 0,10193063 ! negative chemotaxis GO:0050919 14 5 0,000 3,813E-03 0,10081051 ! positive regulation of histone modification GO:0031058 5 5 0,000 3,813E-03 0,09971475 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 3,813E-03 0,09864255 ! sensory perception of bitter taste GO:0050913 7 5 0,000 3,813E-03 0,09759316 ! behavioral response to pain GO:0048266 9 5 0,000 3,813E-03 0,09656586 ! clathrin coat assembly GO:0048268 14 5 0,000 3,813E-03 0,09555997 ! Notch receptor processing GO:0007220 8 5 0,000 3,813E-03 0,09457481 ! regulation of dopamine uptake GO:0051584 9 5 0,000 3,813E-03 0,09360976 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 3,813E-03 0,09266421 ! micturition GO:0060073 9 5 0,000 3,813E-03 0,09173757 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 3,813E-03 0,09082928 ! copulation GO:0007620 9 5 0,000 3,813E-03 0,08993879 ! glial cell fate commitment GO:0021781 13 5 0,000 3,813E-03 0,0890656 ! protein maturation by protein folding GO:0022417 13 5 0,000 3,813E-03 0,0882092 ! spermidine metabolic process GO:0008216 7 5 0,000 3,813E-03 0,08736911 ! regulation of potassium ion transport GO:0043266 10 5 0,000 3,813E-03 0,08654488 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 3,813E-03 0,08573604 ! apoptotic cell clearance GO:0043277 20 5 0,000 3,813E-03 0,08494219 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 3,813E-03 0,08416291 ! lipoprotein particle clearance GO:0034381 10 5 0,000 3,813E-03 0,08339779 ! grooming behavior GO:0007625 6 5 0,000 3,813E-03 0,08264646 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 3,813E-03 0,08190854 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 3,813E-03 0,08118369 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 3,813E-03 0,08047155 ! response to protozoan GO:0001562 10 5 0,000 3,813E-03 0,0797718 ! positive regulation of glycolysis GO:0045821 14 5 0,000 3,813E-03 0,07908411 ! lymph vessel development GO:0001945 10 5 0,000 3,813E-03 0,07840818 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 3,813E-03 0,0777437 ! endochondral ossification GO:0001958 16 5 0,000 3,813E-03 0,07709039 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 3,813E-03 0,07644797 ! parathyroid gland development GO:0060017 13 5 0,000 3,813E-03 0,07581617 ! anagen GO:0042640 6 5 0,000 3,813E-03 0,07519473 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 3,813E-03 0,07458339 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 3,813E-03 0,07398191 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 3,813E-03 0,07339005 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 3,813E-03 0,07280759 ! dorsal spinal cord development GO:0021516 7 5 0,000 3,813E-03 0,07223431 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 3,813E-03 0,07166997 ! sphingoid catabolic process GO:0046521 6 5 0,000 3,813E-03 0,07111439 ! skeletal myofibril assembly GO:0014866 10 5 0,000 3,813E-03 0,07056736 ! smooth muscle tissue development GO:0048745 28 5 0,000 3,813E-03 0,07002868 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 3,813E-03 0,06949816 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 3,813E-03 0,06897561 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 3,813E-03 0,06846087 ! cardiac muscle fiber development GO:0048739 10 5 0,000 3,813E-03 0,06795375 ! transepithelial chloride transport GO:0030321 9 5 0,000 3,813E-03 0,06745409 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 3,813E-03 0,06696173 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 3,813E-03 0,0664765 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 3,813E-03 0,06599825 ! neutrophil mediated immunity GO:0002446 7 5 0,000 3,813E-03 0,06552683 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 3,813E-03 0,0650621 ! histidine catabolic process GO:0006548 6 5 0,000 3,813E-03 0,06460392 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 3,813E-03 0,06415215 ! microvillus organization GO:0032528 7 5 0,000 3,813E-03 0,06370664 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 3,813E-03 0,06326729 ! L-serine biosynthetic process GO:0006564 6 5 0,000 3,813E-03 0,06283395 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 3,813E-03 0,06240651 ! tryptophan metabolic process GO:0006568 9 5 0,000 3,813E-03 0,06198484 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 3,813E-03 0,06156884 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 3,813E-03 0,06115838 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 3,813E-03 0,06075336 ! polyol catabolic process GO:0046174 7 5 0,000 3,813E-03 0,06035366 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 3,813E-03 0,05995919 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 3,813E-03 0,05956985 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 3,813E-03 0,05918553 ! muscle cell migration GO:0014812 8 5 0,000 3,813E-03 0,05880613 ! mitochondrial fission GO:0000266 8 5 0,000 3,813E-03 0,05843157 ! sister chromatid cohesion GO:0007062 12 5 0,000 3,813E-03 0,05806175 ! mRNA transcription GO:0009299 9 5 0,000 3,813E-03 0,05769658 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 3,813E-03 0,05733598 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 3,813E-03 0,05697986 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 3,813E-03 0,05662813 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 3,813E-03 0,05628072 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 3,813E-03 0,05593754 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 3,813E-03 0,05559853 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 3,813E-03 0,0552636 ! response to food GO:0032094 6 5 0,000 3,813E-03 0,05493268 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 3,813E-03 0,0546057 ! positive regulation of transporter activity GO:0032411 8 5 0,000 3,813E-03 0,05428258 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 3,813E-03 0,05396328 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 3,813E-03 0,0536477 ! paraxial mesoderm development GO:0048339 14 5 0,000 3,813E-03 0,0533358 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 3,813E-03 0,0530275 ! forebrain neuron development GO:0021884 13 5 0,000 3,813E-03 0,05272274 ! lipoprotein catabolic process GO:0042159 11 5 0,000 3,813E-03 0,05242147 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 3,813E-03 0,05212362 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 3,813E-03 0,05182913 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 3,813E-03 0,05153796 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 3,813E-03 0,05125004 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 3,813E-03 0,05096532 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 3,813E-03 0,05068374 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 3,813E-03 0,05040526 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 3,813E-03 0,05012982 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 3,813E-03 0,04985737 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 3,813E-03 0,04958787 ! basic amino acid transport GO:0015802 11 5 0,000 3,813E-03 0,04932127 ! cellular glucose homeostasis GO:0001678 5 5 0,000 3,813E-03 0,04905752 ! early endosome to late endosome transport GO:0045022 12 5 0,000 3,813E-03 0,04879658 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 3,813E-03 0,0485384 ! depyrimidination GO:0045008 10 5 0,000 3,813E-03 0,04828293 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 3,813E-03 0,04803014 ! regulation of centrosome cycle GO:0046605 7 5 0,000 3,813E-03 0,04777998 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 3,813E-03 0,04753242 ! zinc ion homeostasis GO:0055069 8 5 0,000 3,813E-03 0,04728741 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 3,813E-03 0,04704491 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 3,813E-03 0,04680488 ! forebrain morphogenesis GO:0048853 13 5 0,000 3,813E-03 0,04656729 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 3,813E-03 0,0463321 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 3,813E-03 0,04609928 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 3,813E-03 0,04586878 ! peptidyl-arginine modification GO:0018195 9 5 0,000 3,813E-03 0,04564058 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 3,813E-03 0,04541464 ! positive regulation of organ growth GO:0046622 6 5 0,000 3,813E-03 0,04519092 ! response to arsenic GO:0046685 10 5 0,000 3,813E-03 0,0449694 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 3,813E-03 0,04475003 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 3,813E-03 0,0445328 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 3,813E-03 0,04431767 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 3,813E-03 0,0441046 ! response to cadmium ion GO:0046686 7 5 0,000 3,813E-03 0,04389357 ! bile acid biosynthetic process GO:0006699 6 5 0,000 3,813E-03 0,04368456 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 3,813E-03 0,04347752 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 3,813E-03 0,04327244 ! decidualization GO:0046697 11 5 0,000 3,813E-03 0,04306928 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 3,813E-03 0,04286802 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 3,813E-03 0,04266864 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 3,813E-03 0,0424711 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 3,813E-03 0,04227538 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 3,813E-03 0,04208145 ! base conversion or substitution editing GO:0016553 5 5 0,000 3,813E-03 0,0418893 ! neural tube patterning GO:0021532 7 5 0,000 3,813E-03 0,04169889 ! embryonic cleavage GO:0040016 6 5 0,000 3,813E-03 0,04151021 ! peroxisome fission GO:0016559 5 5 0,000 3,813E-03 0,04132323 ! histone demethylation GO:0016577 10 5 0,000 3,813E-03 0,04113792 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 3,813E-03 0,04095427 ! mitotic recombination GO:0006312 9 5 0,000 3,813E-03 0,04077225 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 3,813E-03 0,04059184 ! metaphase plate congression GO:0051310 7 5 0,000 3,813E-03 0,04041303 ! regulation of sterol transport GO:0032371 7 5 0,000 3,813E-03 0,04023578 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 3,813E-03 0,04006007 ! enteric nervous system development GO:0048484 8 5 0,000 3,813E-03 0,0398859 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 3,813E-03 0,03971323 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 3,813E-03 0,03954206 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 3,813E-03 0,03937235 ! muscle cell proliferation GO:0033002 11 5 0,000 3,813E-03 0,03920409 ! skeletal muscle regeneration GO:0043403 8 5 0,000 3,813E-03 0,03903726 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 3,813E-03 0,03887185 ! plasminogen activation GO:0031639 5 5 0,000 3,813E-03 0,03870783 ! B cell homeostasis GO:0001782 13 5 0,000 3,813E-03 0,0385452 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 3,813E-03 0,03838392 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 3,813E-03 0,03822399 ! metaphase GO:0051323 8 5 0,000 3,813E-03 0,03806538 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 3,813E-03 0,03790809 ! cellular response to nutrient GO:0031670 8 5 0,000 3,813E-03 0,03775209 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 3,813E-03 0,03759736 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 3,813E-03 0,03744391 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 3,813E-03 0,03729169 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 3,813E-03 0,03714072 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 3,813E-03 0,03699095 ! response to redox state GO:0051775 5 5 0,000 3,813E-03 0,0368424 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 3,813E-03 0,03669503 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 3,813E-03 0,03654883 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 3,813E-03 0,0364038 ! regulation of telomerase activity GO:0051972 6 5 0,000 3,813E-03 0,03625991 ! galactolipid metabolic process GO:0019374 7 5 0,000 3,813E-03 0,03611715 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 3,813E-03 0,03597552 ! porphyrin catabolic process GO:0006787 12 5 0,000 3,813E-03 0,03583499 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 3,813E-03 0,03569555 ! striatum development GO:0021756 9 5 0,000 3,813E-03 0,0355572 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 3,813E-03 0,03541991 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 3,813E-03 0,03528368 ! glial cell migration GO:0008347 11 5 0,000 3,813E-03 0,03514849 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 3,813E-03 0,03501434 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 3,813E-03 0,0348812 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 3,813E-03 0,03474908 ! somatic stem cell maintenance GO:0035019 15 5 0,000 3,813E-03 0,03461795 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 3,813E-03 0,03448781 ! negative regulation of lipase activity GO:0060192 8 5 0,000 3,813E-03 0,03435864 ! neuroprotection GO:0043526 6 5 0,000 3,813E-03 0,03423044 ! neural plate development GO:0001840 8 5 0,000 3,813E-03 0,03410319 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 3,813E-03 0,03397688 ! regulation of sensory perception GO:0051931 7 5 0,000 3,813E-03 0,0338515 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 3,813E-03 0,03372705 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 3,813E-03 0,0336035 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 3,813E-03 0,03348086 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 3,813E-03 0,03335912 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 3,813E-03 0,03323825 ! sequestering of calcium ion GO:0051208 7 5 0,000 3,813E-03 0,03311826 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 3,813E-03 0,03299913 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 3,813E-03 0,03288085 ! spindle assembly GO:0051225 6 5 0,000 3,813E-03 0,03276342 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 3,813E-03 0,03264682 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 3,813E-03 0,03253105 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 3,813E-03 0,0324161 ! drug metabolic process GO:0017144 6 5 0,000 3,813E-03 0,03230196 ! stem cell division GO:0017145 11 5 0,000 3,813E-03 0,03218862 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 3,813E-03 0,03207607 ! organ regeneration GO:0031100 7 5 0,000 3,813E-03 0,03196431 ! carnitine metabolic process GO:0009437 7 5 0,000 3,813E-03 0,03185332 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 3,813E-03 0,0317431 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 3,813E-03 0,03163364 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 4,574E-03 0,03781611 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 4,574E-03 0,03768661 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 4,574E-03 0,03755798 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 4,574E-03 0,03743023 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 4,574E-03 0,03730335 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 4,574E-03 0,03717733 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 4,574E-03 0,03705215 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 4,574E-03 0,03692781 ! sleep GO:0030431 13 6 0,000 4,574E-03 0,03680431 ! response to oxygen radical GO:0000305 11 6 0,000 4,574E-03 0,03668163 ! positive regulation of axon extension GO:0045773 11 6 0,000 4,574E-03 0,03655976 ! myoblast cell fate commitment GO:0048625 16 6 0,000 4,574E-03 0,0364387 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 4,574E-03 0,03631844 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 4,574E-03 0,03619898 ! regulation of interferon-beta production GO:0032648 8 6 0,000 4,574E-03 0,03608029 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 4,574E-03 0,03596238 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 4,574E-03 0,03584524 ! forebrain regionalization GO:0021871 8 6 0,000 4,574E-03 0,03572886 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 4,574E-03 0,03561323 ! male meiosis GO:0007140 7 6 0,000 4,574E-03 0,03549835 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 4,574E-03 0,03538421 ! response to zinc ion GO:0010043 9 6 0,000 4,574E-03 0,0352708 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 4,574E-03 0,03515811 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 4,574E-03 0,03504614 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 4,574E-03 0,03493489 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 4,574E-03 0,03482433 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 4,574E-03 0,03471448 ! malate metabolic process GO:0006108 11 6 0,000 4,574E-03 0,03460531 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 4,574E-03 0,03449683 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 4,574E-03 0,03438903 ! protein refolding GO:0042026 15 6 0,000 4,574E-03 0,0342819 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 4,574E-03 0,03417543 ! opsonization GO:0008228 8 6 0,000 4,574E-03 0,03406962 ! mating behavior GO:0007617 7 6 0,000 4,574E-03 0,03396447 ! neuron remodeling GO:0016322 15 6 0,000 4,574E-03 0,03385997 ! erythrocyte maturation GO:0043249 7 6 0,000 4,574E-03 0,0337561 ! embryonic hemopoiesis GO:0035162 14 6 0,000 4,574E-03 0,03365287 ! equilibrioception GO:0050957 14 6 0,000 4,574E-03 0,03355027 ! protein amino acid dealkylation GO:0008214 12 6 0,000 4,574E-03 0,03344829 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 4,574E-03 0,03334694 ! photoreceptor cell development GO:0042461 10 6 0,000 4,574E-03 0,03324619 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 4,574E-03 0,03314605 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 4,574E-03 0,03304651 ! response to interferon-gamma GO:0034341 15 6 0,000 4,574E-03 0,03294757 ! toxin metabolic process GO:0009404 11 6 0,000 4,574E-03 0,03284922 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 4,574E-03 0,03275145 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 4,574E-03 0,03265427 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 4,574E-03 0,03255766 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 4,574E-03 0,03246162 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 4,574E-03 0,03236614 ! cGMP-mediated signaling GO:0019934 13 6 0,000 4,574E-03 0,03227123 ! activation of MAPKKK activity GO:0000185 12 6 0,000 4,574E-03 0,03217687 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 4,574E-03 0,03208306 ! thymic T cell selection GO:0045061 12 6 0,000 4,574E-03 0,03198979 ! protein lipoylation GO:0009249 10 6 0,000 4,574E-03 0,03189707 ! cysteine metabolic process GO:0006534 10 6 0,000 4,574E-03 0,03180488 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 4,574E-03 0,03171322 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 4,574E-03 0,03162209 ! glutamate catabolic process GO:0006538 10 6 0,000 4,574E-03 0,03153149 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 4,574E-03 0,0314414 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 4,574E-03 0,03135182 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 4,574E-03 0,03126275 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 4,574E-03 0,03117419 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 4,574E-03 0,03108613 ! hyperosmotic response GO:0006972 9 6 0,000 4,574E-03 0,03099856 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 4,574E-03 0,03091149 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 4,574E-03 0,0308249 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 4,574E-03 0,0307388 ! urea metabolic process GO:0019627 7 6 0,000 4,574E-03 0,03065317 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 4,574E-03 0,03056802 ! neutrophil activation GO:0042119 8 6 0,000 4,574E-03 0,03048335 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 4,574E-03 0,03039914 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 4,574E-03 0,0303154 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 4,574E-03 0,03023211 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 4,574E-03 0,03014928 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 4,574E-03 0,03006691 ! neuron apoptosis GO:0051402 9 6 0,000 4,574E-03 0,02998498 ! nucleoside salvage GO:0043174 9 6 0,000 4,574E-03 0,0299035 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 4,574E-03 0,02982246 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 4,574E-03 0,02974186 ! T cell mediated immunity GO:0002456 16 6 0,000 4,574E-03 0,02966169 ! negative regulation of platelet activation GO:0010544 9 6 0,000 4,574E-03 0,02958196 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 4,574E-03 0,02950265 ! carnitine transport GO:0015879 10 6 0,000 4,574E-03 0,02942377 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 4,574E-03 0,0293453 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 4,574E-03 0,02926726 ! positive regulation of exocytosis GO:0045921 8 6 0,000 4,574E-03 0,02918963 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 4,574E-03 0,0291124 ! 5S class rRNA transcription GO:0042791 11 6 0,000 4,574E-03 0,02903559 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 4,574E-03 0,02895918 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 4,574E-03 0,02888317 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 4,574E-03 0,02880756 ! sodium ion homeostasis GO:0055078 11 6 0,000 4,574E-03 0,02873235 ! establishment of spindle localization GO:0051293 12 6 0,000 4,574E-03 0,02865752 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 4,574E-03 0,02858309 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 4,574E-03 0,02850904 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 4,574E-03 0,02843537 ! neural nucleus development GO:0048857 14 6 0,000 4,574E-03 0,02836208 ! response to UV-C GO:0010225 11 6 0,000 4,574E-03 0,02828917 ! astrocyte development GO:0014002 15 6 0,000 4,574E-03 0,02821664 ! protein targeting to lysosome GO:0006622 10 6 0,000 4,574E-03 0,02814447 ! purine base biosynthetic process GO:0009113 17 6 0,000 4,574E-03 0,02807268 ! interaction with symbiont GO:0051702 13 6 0,000 4,574E-03 0,02800124 ! regulation of dendrite development GO:0050773 16 6 0,000 4,574E-03 0,02793017 ! skeletal muscle contraction GO:0003009 6 6 0,000 4,574E-03 0,02785947 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 4,574E-03 0,02778911 ! response to copper ion GO:0046688 10 6 0,000 4,574E-03 0,02771912 ! response to exogenous dsRNA GO:0043330 10 6 0,000 4,574E-03 0,02764947 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 4,574E-03 0,02758017 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 4,574E-03 0,02751122 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 4,574E-03 0,02744262 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 4,574E-03 0,02737435 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 4,574E-03 0,02730642 ! regulation of dopamine secretion GO:0014059 14 6 0,000 4,574E-03 0,02723883 ! nucleoside catabolic process GO:0009164 7 6 0,000 4,574E-03 0,02717158 ! hair follicle maturation GO:0048820 7 6 0,000 4,574E-03 0,02710465 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 4,574E-03 0,02703806 ! Schwann cell development GO:0014044 15 6 0,000 4,574E-03 0,02697179 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 4,574E-03 0,02690584 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 4,574E-03 0,02684022 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 4,574E-03 0,02677491 ! subpallium development GO:0021544 10 6 0,000 4,574E-03 0,02670992 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 4,574E-03 0,02664525 ! histone ubiquitination GO:0016574 8 6 0,000 4,574E-03 0,02658089 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 4,574E-03 0,02651684 ! maintenance of organ identity GO:0048496 9 6 0,000 4,574E-03 0,0264531 ! G2 phase GO:0051319 16 6 0,000 4,574E-03 0,02638966 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 4,574E-03 0,02632653 ! establishment of planar polarity GO:0001736 7 6 0,000 4,574E-03 0,0262637 ! regulation of mast cell activation GO:0033003 12 6 0,000 4,574E-03 0,02620116 ! membrane to membrane docking GO:0022614 14 6 0,000 4,574E-03 0,02613893 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 4,574E-03 0,02607699 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 4,574E-03 0,02601534 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 4,574E-03 0,02595398 ! receptor internalization GO:0031623 10 6 0,000 4,574E-03 0,02589291 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 4,574E-03 0,02583213 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 4,574E-03 0,02577164 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 4,574E-03 0,02571142 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 4,574E-03 0,02565149 ! protein deubiquitination GO:0016579 14 6 0,000 4,574E-03 0,02559183 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 4,574E-03 0,02553246 ! protein destabilization GO:0031648 9 6 0,000 4,574E-03 0,02547335 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 4,574E-03 0,02541452 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 4,574E-03 0,02535597 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 4,574E-03 0,02529768 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 4,574E-03 0,02523965 ! progesterone metabolic process GO:0042448 10 6 0,000 4,574E-03 0,0251819 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 4,574E-03 0,0251244 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 4,574E-03 0,02506717 ! negative regulation of axon extension GO:0030517 21 6 0,000 4,574E-03 0,0250102 ! removal of superoxide radicals GO:0019430 11 6 0,000 4,574E-03 0,02495349 ! triglyceride catabolic process GO:0019433 10 6 0,000 4,574E-03 0,02489703 ! determination of adult lifespan GO:0008340 15 6 0,000 4,574E-03 0,02484083 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 4,574E-03 0,02478488 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 4,574E-03 0,02472919 ! cerebellar cortex formation GO:0021697 8 6 0,000 4,574E-03 0,02467374 ! catecholamine transport GO:0051937 9 6 0,000 4,574E-03 0,02461854 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 4,574E-03 0,02456359 ! sensory cilium assembly GO:0035058 10 6 0,000 4,574E-03 0,02450888 ! organ or tissue specific immune response GO:0002251 7 6 0,000 4,574E-03 0,02445442 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 4,574E-03 0,0244002 ! maternal placenta development GO:0001893 12 6 0,000 4,574E-03 0,02434621 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 4,574E-03 0,02429247 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 4,574E-03 0,02423896 ! negative regulation of B cell activation GO:0050869 13 6 0,000 4,574E-03 0,02418569 ! protein amino acid prenylation GO:0018346 16 6 0,000 4,574E-03 0,02413265 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 4,574E-03 0,02407984 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 4,574E-03 0,02402727 ! positive regulation of coagulation GO:0050820 12 6 0,000 4,574E-03 0,02397492 ! tRNA transcription GO:0009304 14 7 0,000 5,334E-03 0,02789975 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 5,334E-03 0,02783923 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 5,334E-03 0,02777897 ! behavioral response to cocaine GO:0048148 14 7 0,000 5,334E-03 0,02771897 ! regulation of helicase activity GO:0051095 15 7 0,000 5,334E-03 0,02765923 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 5,334E-03 0,02759975 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 5,334E-03 0,02754052 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 5,334E-03 0,02748155 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 5,334E-03 0,02742283 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 5,334E-03 0,02736436 ! prostate gland development GO:0030850 13 7 0,000 5,334E-03 0,02730613 ! nucleotide-sugar transport GO:0015780 12 7 0,000 5,334E-03 0,02724816 ! synaptonemal complex assembly GO:0007130 10 7 0,000 5,334E-03 0,02719043 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 5,334E-03 0,02713295 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 5,334E-03 0,0270757 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 5,334E-03 0,0270187 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 5,334E-03 0,02696194 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 5,334E-03 0,02690542 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 5,334E-03 0,02684913 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 5,334E-03 0,02679308 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 5,334E-03 0,02673726 ! SMAD protein complex assembly GO:0007183 12 7 0,000 5,334E-03 0,02668167 ! glycolipid transport GO:0046836 10 7 0,000 5,334E-03 0,02662631 ! protein amino acid sulfation GO:0006477 10 7 0,000 5,334E-03 0,02657119 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 5,334E-03 0,02651629 ! neuron adhesion GO:0007158 12 7 0,000 5,334E-03 0,02646162 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 5,334E-03 0,02640717 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 5,334E-03 0,02635294 ! actin-myosin filament sliding GO:0033275 11 7 0,000 5,334E-03 0,02629894 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 5,334E-03 0,02624516 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 5,334E-03 0,0261916 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 5,334E-03 0,02613826 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 5,334E-03 0,02608513 ! mRNA stabilization GO:0048255 18 7 0,000 5,334E-03 0,02603222 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 5,334E-03 0,02597952 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 5,334E-03 0,02592704 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 5,334E-03 0,02587476 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 5,334E-03 0,0258227 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 5,334E-03 0,02577085 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 5,334E-03 0,02571921 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 5,334E-03 0,02566777 ! lipoprotein transport GO:0042953 14 7 0,000 5,334E-03 0,02561653 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 5,334E-03 0,0255655 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 5,334E-03 0,02551468 ! rhythmic behavior GO:0007622 15 7 0,000 5,334E-03 0,02546405 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 5,334E-03 0,02541363 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 5,334E-03 0,02536341 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 5,334E-03 0,02531338 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 5,334E-03 0,02526355 ! regulation of odontogenesis GO:0042481 13 7 0,000 5,334E-03 0,02521392 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 5,334E-03 0,02516448 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 5,334E-03 0,02511523 ! mechanosensory behavior GO:0007638 14 7 0,000 5,334E-03 0,02506618 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 5,334E-03 0,02501732 ! positive regulation of isotype switching GO:0045830 15 7 0,000 5,334E-03 0,02496864 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 5,334E-03 0,02492016 ! protein-cofactor linkage GO:0018065 13 7 0,000 5,334E-03 0,02487187 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 5,334E-03 0,02482376 ! spinal cord patterning GO:0021511 13 7 0,000 5,334E-03 0,02477584 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 5,334E-03 0,0247281 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 5,334E-03 0,02468054 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 5,334E-03 0,02463317 ! adrenal gland development GO:0030325 17 7 0,000 5,334E-03 0,02458598 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 5,334E-03 0,02453897 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 5,334E-03 0,02449214 ! ovulation GO:0030728 9 7 0,000 5,334E-03 0,02444549 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 5,334E-03 0,02439902 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 5,334E-03 0,02435272 ! microtubule nucleation GO:0007020 20 7 0,000 5,334E-03 0,0243066 ! proline biosynthetic process GO:0006561 10 7 0,000 5,334E-03 0,02426065 ! thyroid hormone generation GO:0006590 13 7 0,000 5,334E-03 0,02421487 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 5,334E-03 0,02416927 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 5,334E-03 0,02412384 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 5,334E-03 0,02407858 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 5,334E-03 0,02403349 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 5,334E-03 0,02398857 ! galactose metabolic process GO:0006012 13 7 0,000 5,334E-03 0,02394381 ! vesicle fusion GO:0006906 17 7 0,000 5,334E-03 0,02389922 ! response to dietary excess GO:0002021 8 7 0,000 5,334E-03 0,0238548 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 5,334E-03 0,02381054 ! intracellular pH reduction GO:0051452 11 7 0,000 5,334E-03 0,02376645 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 5,334E-03 0,02372252 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 5,334E-03 0,02367875 ! organ growth GO:0035265 15 7 0,000 5,334E-03 0,02363514 ! purine salvage GO:0043101 10 7 0,000 5,334E-03 0,0235917 ! nucleoside transport GO:0015858 8 7 0,000 5,334E-03 0,02354841 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 5,334E-03 0,02350528 ! parturition GO:0007567 14 7 0,000 5,334E-03 0,02346231 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 5,334E-03 0,0234195 ! rRNA modification GO:0000154 14 7 0,000 5,334E-03 0,02337684 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 5,334E-03 0,02333433 ! spindle checkpoint GO:0031577 15 7 0,000 5,334E-03 0,02329198 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 5,334E-03 0,02324979 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 5,334E-03 0,02320775 ! macrophage differentiation GO:0030225 11 7 0,000 5,334E-03 0,02316585 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 5,334E-03 0,02312411 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 5,334E-03 0,02308252 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 5,334E-03 0,02304108 ! hyaluronan metabolic process GO:0030212 8 7 0,000 5,334E-03 0,02299979 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 5,334E-03 0,02295865 ! anterograde axon cargo transport GO:0008089 18 7 0,000 5,334E-03 0,02291765 ! fibrinolysis GO:0042730 10 7 0,000 5,334E-03 0,0228768 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 5,334E-03 0,02283609 ! eating behavior GO:0042755 7 7 0,000 5,334E-03 0,02279553 ! B cell lineage commitment GO:0002326 21 7 0,000 5,334E-03 0,02275511 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 5,334E-03 0,02271484 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 5,334E-03 0,02267471 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 5,334E-03 0,02263471 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 5,334E-03 0,02259486 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 5,334E-03 0,02255516 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 5,334E-03 0,02251558 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 5,334E-03 0,02247615 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 5,334E-03 0,02243686 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 5,334E-03 0,0223977 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 5,334E-03 0,02235868 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 5,334E-03 0,0223198 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 5,334E-03 0,02228105 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 5,334E-03 0,02224243 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 5,334E-03 0,02220395 ! regulation of meiosis GO:0040020 12 7 0,000 5,334E-03 0,0221656 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 5,334E-03 0,02212738 ! T cell lineage commitment GO:0002360 16 7 0,000 5,334E-03 0,0220893 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 5,334E-03 0,02205135 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 5,334E-03 0,02201352 ! oxygen homeostasis GO:0032364 12 7 0,000 5,334E-03 0,02197583 ! transcription termination GO:0006353 13 7 0,000 5,334E-03 0,02193826 ! response to tumor cell GO:0002347 13 7 0,000 5,334E-03 0,02190082 ! regulation of respiratory burst GO:0060263 11 7 0,000 5,334E-03 0,02186351 ! coenzyme A metabolic process GO:0015936 12 7 0,000 5,334E-03 0,02182633 ! anaphase GO:0051322 17 7 0,000 5,334E-03 0,02178928 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 5,334E-03 0,02175234 ! axonal fasciculation GO:0007413 18 7 0,000 5,334E-03 0,02171554 ! negative regulation of nuclear division GO:0051784 14 7 0,000 5,334E-03 0,02167886 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 5,334E-03 0,0216423 ! peptidyl-threonine modification GO:0018210 25 7 0,000 5,334E-03 0,02160586 ! diuresis GO:0030146 12 7 0,000 5,334E-03 0,02156955 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 5,334E-03 0,02153336 ! thiamin metabolic process GO:0006772 7 7 0,000 5,334E-03 0,02149729 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 5,334E-03 0,02146134 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 5,334E-03 0,02142551 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 5,334E-03 0,02138981 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 5,334E-03 0,02135422 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 5,334E-03 0,02131874 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 5,334E-03 0,02128339 ! melanin biosynthetic process GO:0042438 8 7 0,000 5,334E-03 0,02124815 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 5,334E-03 0,02121303 ! dopamine biosynthetic process GO:0042416 18 7 0,000 5,334E-03 0,02117803 ! glycolipid catabolic process GO:0019377 15 7 0,000 5,334E-03 0,02114314 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 5,334E-03 0,02110836 ! lymph node development GO:0048535 10 7 0,000 5,334E-03 0,0210737 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 5,334E-03 0,02103915 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 5,334E-03 0,02100472 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 5,334E-03 0,0209704 ! endosome to lysosome transport GO:0008333 11 7 0,000 5,334E-03 0,02093619 ! protein modification by small protein removal GO:0070646 16 7 0,000 5,334E-03 0,02090209 ! adult feeding behavior GO:0008343 9 7 0,000 5,334E-03 0,0208681 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 5,334E-03 0,02083423 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 5,334E-03 0,02080046 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 5,334E-03 0,0207668 ! muscle adaptation GO:0043500 14 7 0,000 5,334E-03 0,02073325 ! embryonic heart tube development GO:0035050 10 7 0,000 5,334E-03 0,02069981 ! retina homeostasis GO:0001895 12 7 0,000 5,334E-03 0,02066648 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 5,334E-03 0,02063325 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 5,334E-03 0,02060013 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 5,334E-03 0,02056712 ! protein prenylation GO:0018342 18 7 0,000 5,334E-03 0,02053421 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 5,334E-03 0,02050141 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 5,334E-03 0,02046871 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 5,334E-03 0,02043612 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 6,094E-03 0,02330992 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 6,094E-03 0,02327292 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 6,094E-03 0,02323604 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 6,094E-03 0,02319927 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 6,094E-03 0,02316262 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 6,094E-03 0,02312609 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 6,094E-03 0,02308967 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 6,094E-03 0,02305337 ! neutral lipid catabolic process GO:0046461 13 8 0,000 6,094E-03 0,02301718 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 6,094E-03 0,0229811 ! meiotic prophase I GO:0007128 13 8 0,000 6,094E-03 0,02294513 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 6,094E-03 0,02290928 ! oligopeptide transport GO:0006857 15 8 0,000 6,094E-03 0,02287354 ! UTP metabolic process GO:0046051 8 8 0,000 6,094E-03 0,02283791 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 6,094E-03 0,0228024 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 6,094E-03 0,02276699 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 6,094E-03 0,02273169 ! macrophage chemotaxis GO:0048246 12 8 0,000 6,094E-03 0,0226965 ! succinate metabolic process GO:0006105 14 8 0,000 6,094E-03 0,02266142 ! membrane hyperpolarization GO:0060081 10 8 0,000 6,094E-03 0,02262645 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 6,094E-03 0,02259159 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 6,094E-03 0,02255683 ! T-helper 1 type immune response GO:0042088 12 8 0,000 6,094E-03 0,02252218 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 6,094E-03 0,02248764 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 6,094E-03 0,0224532 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 6,094E-03 0,02241887 ! ganglioside metabolic process GO:0001573 19 8 0,000 6,094E-03 0,02238464 ! reflex GO:0060004 16 8 0,000 6,094E-03 0,02235052 ! negative regulation of endocytosis GO:0045806 11 8 0,000 6,094E-03 0,0223165 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 6,094E-03 0,02228259 ! endothelial cell differentiation GO:0045446 17 8 0,000 6,094E-03 0,02224877 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 6,094E-03 0,02221506 ! glycerolipid catabolic process GO:0046503 13 8 0,000 6,094E-03 0,02218145 ! hemoglobin metabolic process GO:0020027 13 8 0,000 6,094E-03 0,02214795 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 6,094E-03 0,02211454 ! pigment granule organization GO:0048753 16 8 0,000 6,094E-03 0,02208124 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 6,094E-03 0,02204803 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 6,094E-03 0,02201493 ! astrocyte differentiation GO:0048708 18 8 0,000 6,094E-03 0,02198192 ! histidine metabolic process GO:0006547 16 8 0,000 6,094E-03 0,02194901 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 6,094E-03 0,0219162 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 6,094E-03 0,02188349 ! glycine catabolic process GO:0006546 13 8 0,000 6,094E-03 0,02185088 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 6,094E-03 0,02181836 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 6,094E-03 0,02178595 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 6,094E-03 0,02175362 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 6,094E-03 0,02172139 ! regulation of pigmentation during development GO:0048070 24 8 0,000 6,094E-03 0,02168926 ! melanin metabolic process GO:0006582 15 8 0,000 6,094E-03 0,02165722 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 6,094E-03 0,02162528 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 6,094E-03 0,02159343 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 6,094E-03 0,02156168 ! macrophage activation GO:0042116 12 8 0,000 6,094E-03 0,02153002 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 6,094E-03 0,02149845 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 6,094E-03 0,02146697 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 6,094E-03 0,02143559 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 6,094E-03 0,02140429 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 6,094E-03 0,02137309 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 6,094E-03 0,02134198 ! regulation of vascular permeability GO:0043114 12 8 0,000 6,094E-03 0,02131096 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 6,094E-03 0,02128003 ! osteoblast development GO:0002076 16 8 0,000 6,094E-03 0,02124919 ! positive regulation of vasodilation GO:0045909 13 8 0,000 6,094E-03 0,02121844 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 6,094E-03 0,02118778 ! negative regulation of translational initiation GO:0045947 10 8 0,000 6,094E-03 0,0211572 ! Schwann cell differentiation GO:0014037 19 8 0,000 6,094E-03 0,02112672 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 6,094E-03 0,02109632 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 6,094E-03 0,02106601 ! response to UV-B GO:0010224 16 8 0,000 6,094E-03 0,02103578 ! protein targeting to vacuole GO:0006623 12 8 0,000 6,094E-03 0,02100565 ! protein retention in ER lumen GO:0006621 14 8 0,000 6,094E-03 0,0209756 ! intermediate filament organization GO:0045109 12 8 0,000 6,094E-03 0,02094563 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 6,094E-03 0,02091575 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 6,094E-03 0,02088596 ! cellular extravasation GO:0045123 12 8 0,000 6,094E-03 0,02085625 ! cardiac muscle cell development GO:0055013 13 8 0,000 6,094E-03 0,02082662 ! regulation of circadian rhythm GO:0042752 16 8 0,000 6,094E-03 0,02079708 ! response to antibiotic GO:0046677 11 8 0,000 6,094E-03 0,02076762 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 6,094E-03 0,02073825 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 6,094E-03 0,02070896 ! DNA topological change GO:0006265 12 8 0,000 6,094E-03 0,02067975 ! response to tropane GO:0014073 15 8 0,000 6,094E-03 0,02065062 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 6,094E-03 0,02062158 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 6,094E-03 0,02059261 ! melanosome transport GO:0032402 13 8 0,000 6,094E-03 0,02056373 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 0,000 6,094E-03 0,02053493 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 6,094E-03 0,02050621 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 6,094E-03 0,02047757 ! mast cell activation GO:0045576 14 8 0,000 6,094E-03 0,02044901 ! multicellular organismal aging GO:0010259 18 8 0,000 6,094E-03 0,02042053 ! dendrite morphogenesis GO:0048813 13 8 0,000 6,094E-03 0,02039213 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 6,094E-03 0,02036381 ! nucleosome disassembly GO:0006337 14 8 0,000 6,094E-03 0,02033556 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 6,094E-03 0,0203074 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 6,094E-03 0,02027931 ! leukocyte activation during immune response GO:0002366 13 8 0,000 6,094E-03 0,0202513 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 6,094E-03 0,02022337 ! establishment of chromosome localization GO:0051303 12 8 0,000 6,094E-03 0,02019551 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 6,094E-03 0,02016773 ! intracellular lipid transport GO:0032365 13 8 0,000 6,094E-03 0,02014003 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 6,094E-03 0,0201124 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 6,094E-03 0,02008485 ! regulation of macrophage activation GO:0043030 15 8 0,000 6,094E-03 0,02005737 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 6,094E-03 0,02002997 ! positive regulation of epidermis development GO:0045684 13 8 0,000 6,094E-03 0,02000265 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 6,094E-03 0,0199754 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 6,094E-03 0,01994822 ! hormone catabolic process GO:0042447 17 8 0,000 6,094E-03 0,01992112 ! positive regulation of glucose import GO:0046326 8 8 0,000 6,094E-03 0,01989409 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 6,094E-03 0,01986713 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 6,094E-03 0,01984025 ! ATP catabolic process GO:0006200 11 8 0,000 6,094E-03 0,01981343 ! blastocyst growth GO:0001832 19 8 0,000 6,094E-03 0,0197867 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 6,094E-03 0,01976003 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 6,094E-03 0,01973343 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 6,094E-03 0,01970691 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 6,094E-03 0,01968046 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 6,094E-03 0,01965408 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 6,094E-03 0,01962777 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 6,094E-03 0,01960153 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 6,094E-03 0,01957536 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 6,094E-03 0,01954925 ! amino sugar catabolic process GO:0046348 10 8 0,000 6,094E-03 0,01952322 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 6,094E-03 0,01949726 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 6,094E-03 0,01947137 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 6,094E-03 0,01944555 ! behavioral response to nicotine GO:0035095 12 8 0,000 6,094E-03 0,01941979 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 6,094E-03 0,0193941 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 6,094E-03 0,01936848 ! NAD biosynthetic process GO:0009435 13 8 0,000 6,094E-03 0,01934293 ! regulation of developmental growth GO:0048638 15 9 0,000 6,853E-03 0,02172419 ! axon extension GO:0048675 15 9 0,000 6,853E-03 0,02169561 ! autophagic vacuole formation GO:0000045 15 9 0,000 6,853E-03 0,0216671 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 6,853E-03 0,02163867 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 6,853E-03 0,02161031 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 6,853E-03 0,02158202 ! pentose-phosphate shunt GO:0006098 16 9 0,000 6,853E-03 0,02155381 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 6,853E-03 0,02152567 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 6,853E-03 0,02149761 ! cell proliferation in forebrain GO:0021846 15 9 0,000 6,853E-03 0,02146961 ! phosphate transport GO:0006817 19 9 0,000 6,853E-03 0,02144169 ! reproductive behavior GO:0019098 19 9 0,000 6,853E-03 0,02141385 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 6,853E-03 0,02138607 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 6,853E-03 0,02135837 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 6,853E-03 0,02133074 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 6,853E-03 0,02130318 ! GTP metabolic process GO:0046039 9 9 0,000 6,853E-03 0,02127569 ! RNA methylation GO:0001510 15 9 0,000 6,853E-03 0,02124828 ! elastic fiber assembly GO:0048251 15 9 0,000 6,853E-03 0,02122093 ! induction of positive chemotaxis GO:0050930 15 9 0,000 6,853E-03 0,02119365 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 6,853E-03 0,02116645 ! artery development GO:0060840 24 9 0,000 6,853E-03 0,02113931 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 6,853E-03 0,02111224 ! regulation of glycolysis GO:0006110 21 9 0,000 6,853E-03 0,02108525 ! cerebral cortex cell migration GO:0021795 15 9 0,000 6,853E-03 0,02105832 ! keratinocyte proliferation GO:0043616 14 9 0,000 6,853E-03 0,02103146 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 6,853E-03 0,02100467 ! chemosensory behavior GO:0007635 20 9 0,000 6,853E-03 0,02097794 ! microtubule bundle formation GO:0001578 21 9 0,000 6,853E-03 0,02095129 ! middle ear morphogenesis GO:0042474 14 9 0,000 6,853E-03 0,0209247 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 6,853E-03 0,02089818 ! leukocyte degranulation GO:0043299 16 9 0,000 6,853E-03 0,02087173 ! bile acid and bile salt transport GO:0015721 13 9 0,000 6,853E-03 0,02084534 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 6,853E-03 0,02081902 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 6,853E-03 0,02079277 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 6,853E-03 0,02076658 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 6,853E-03 0,02074046 ! protein targeting to ER GO:0045047 22 9 0,000 6,853E-03 0,0207144 ! ceramide biosynthetic process GO:0046513 19 9 0,000 6,853E-03 0,02068841 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 6,853E-03 0,02066249 ! T cell selection GO:0045058 23 9 0,000 6,853E-03 0,02063662 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 6,853E-03 0,02061083 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 6,853E-03 0,0205851 ! phosphagen metabolic process GO:0006599 12 9 0,000 6,853E-03 0,02055943 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 6,853E-03 0,02053383 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 6,853E-03 0,02050829 ! regulation of type I interferon production GO:0032479 12 9 0,000 6,853E-03 0,02048281 ! mannose metabolic process GO:0006013 13 9 0,000 6,853E-03 0,0204574 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 6,853E-03 0,02043205 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 6,853E-03 0,02040676 ! Rac protein signal transduction GO:0016601 17 9 0,000 6,853E-03 0,02038154 ! receptor clustering GO:0043113 18 9 0,000 6,853E-03 0,02035637 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 6,853E-03 0,02033127 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 6,853E-03 0,02030624 ! ruffle organization GO:0031529 15 9 0,000 6,853E-03 0,02028126 ! retinol metabolic process GO:0042572 18 9 0,000 6,853E-03 0,02025634 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 6,853E-03 0,02023149 ! behavioral fear response GO:0001662 22 9 0,000 6,853E-03 0,0202067 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 6,853E-03 0,02018196 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 6,853E-03 0,02015729 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 6,853E-03 0,02013268 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 6,853E-03 0,02010813 ! protein heterooligomerization GO:0051291 16 9 0,000 6,853E-03 0,02008363 ! oligodendrocyte development GO:0014003 10 9 0,000 6,853E-03 0,0200592 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 6,853E-03 0,02003483 ! segment specification GO:0007379 13 9 0,000 6,853E-03 0,02001051 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 6,853E-03 0,01998626 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 6,853E-03 0,01996206 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 6,853E-03 0,01993792 ! response to amine stimulus GO:0014075 13 9 0,000 6,853E-03 0,01991384 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 6,853E-03 0,01988982 ! erythrocyte development GO:0048821 15 9 0,000 6,853E-03 0,01986586 ! gas homeostasis GO:0033483 16 9 0,000 6,853E-03 0,01984195 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 6,853E-03 0,0198181 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 6,853E-03 0,01979431 ! renal water homeostasis GO:0003091 14 9 0,000 6,853E-03 0,01977058 ! postreplication repair GO:0006301 22 9 0,000 6,853E-03 0,0197469 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 6,853E-03 0,01972328 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 6,853E-03 0,01969972 ! icosanoid secretion GO:0032309 15 9 0,000 6,853E-03 0,01967621 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 6,853E-03 0,01965276 ! cerebellum morphogenesis GO:0021587 14 9 0,000 6,853E-03 0,01962936 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 6,853E-03 0,01960602 ! regulation of cell division GO:0051302 15 9 0,000 6,853E-03 0,01958274 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 6,853E-03 0,01955951 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 6,853E-03 0,01953633 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 6,853E-03 0,01951321 ! sterol catabolic process GO:0016127 11 9 0,000 6,853E-03 0,01949015 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 6,853E-03 0,01946713 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 6,853E-03 0,01944418 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 6,853E-03 0,01942128 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 6,853E-03 0,01939843 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 6,853E-03 0,01937563 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 6,853E-03 0,01935289 ! musculoskeletal movement GO:0050881 14 9 0,000 6,853E-03 0,0193302 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 6,853E-03 0,01930757 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 6,853E-03 0,01928499 ! regulation of synaptogenesis GO:0051963 15 9 0,000 6,853E-03 0,01926246 ! purine base metabolic process GO:0006144 21 9 0,000 6,853E-03 0,01923998 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 6,853E-03 0,01921756 ! pigment granule transport GO:0051904 17 9 0,000 6,853E-03 0,01919518 ! regulation of fibrinolysis GO:0051917 16 9 0,000 6,853E-03 0,01917286 ! regulation of telomere maintenance GO:0032204 14 9 0,000 6,853E-03 0,0191506 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 6,853E-03 0,01912838 ! regulation of muscle adaptation GO:0043502 14 9 0,000 6,853E-03 0,01910621 ! regulation of amino acid transport GO:0051955 11 9 0,000 6,853E-03 0,0190841 ! mitochondrion localization GO:0051646 15 9 0,000 6,853E-03 0,01906204 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 7,612E-03 0,02114786 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 7,612E-03 0,02112347 ! negative regulation of blood pressure GO:0045776 26 10 0,000 7,612E-03 0,02109914 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 7,612E-03 0,02107486 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 7,612E-03 0,02105063 ! synapsis GO:0007129 13 10 0,000 7,612E-03 0,02102646 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 7,612E-03 0,02100235 ! N-glycan processing GO:0006491 20 10 0,000 7,612E-03 0,02097829 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 7,612E-03 0,02095429 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 7,612E-03 0,02093034 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 7,612E-03 0,02090645 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 7,612E-03 0,02088261 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 7,612E-03 0,02085883 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 7,612E-03 0,0208351 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 7,612E-03 0,02081142 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 7,612E-03 0,0207878 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 7,612E-03 0,02076423 ! androgen metabolic process GO:0008209 17 10 0,000 7,612E-03 0,02074071 ! phospholipid efflux GO:0033700 16 10 0,000 7,612E-03 0,02071725 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 7,612E-03 0,02069384 ! positive regulation of heart contraction GO:0045823 16 10 0,000 7,612E-03 0,02067049 ! lung alveolus development GO:0048286 26 10 0,000 7,612E-03 0,02064718 ! pathogenesis GO:0009405 13 10 0,000 7,612E-03 0,02062393 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 7,612E-03 0,02060073 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 7,612E-03 0,02057758 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 7,612E-03 0,02055449 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 7,612E-03 0,02053145 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 7,612E-03 0,02050846 ! endoderm development GO:0007492 16 10 0,000 7,612E-03 0,02048552 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 7,612E-03 0,02046263 ! arginine catabolic process GO:0006527 13 10 0,000 7,612E-03 0,02043979 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 7,612E-03 0,020417 ! proline metabolic process GO:0006560 13 10 0,000 7,612E-03 0,02039427 ! glucan biosynthetic process GO:0009250 14 10 0,000 7,612E-03 0,02037158 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 7,612E-03 0,02034894 ! polyamine biosynthetic process GO:0006596 12 10 0,000 7,612E-03 0,02032636 ! V(D)J recombination GO:0033151 28 10 0,000 7,612E-03 0,02030383 ! reverse cholesterol transport GO:0043691 16 10 0,000 7,612E-03 0,02028134 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 7,612E-03 0,02025891 GO:0021952|central nervous system projection neuron axonogenesis, ! B cell proliferation GO:0042100 18 10 0,000 7,612E-03 0,02023652 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 7,612E-03 0,02021418 ! regulation of sodium ion transport GO:0002028 21 10 0,000 7,612E-03 0,0201919 ! multicellular organism growth GO:0035264 18 10 0,000 7,612E-03 0,02016966 ! phagocytosis, engulfment GO:0006911 28 10 0,000 7,612E-03 0,02014747 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 7,612E-03 0,02012533 ! epithelial cell development GO:0002064 20 10 0,000 7,612E-03 0,02010324 ! lens development in camera-type eye GO:0002088 16 10 0,000 7,612E-03 0,0200812 ! retinoic acid metabolic process GO:0042573 14 10 0,000 7,612E-03 0,0200592 ! macroautophagy GO:0016236 17 10 0,000 7,612E-03 0,02003725 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 7,612E-03 0,02001536 ! positive regulation of translational initiation GO:0045948 11 10 0,000 7,612E-03 0,0199935 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 7,612E-03 0,0199717 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 7,612E-03 0,01994995 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 7,612E-03 0,01992824 ! copper ion homeostasis GO:0055070 13 10 0,000 7,612E-03 0,01990658 ! regulation of bone resorption GO:0045124 25 10 0,000 7,612E-03 0,01988496 ! regulation of gliogenesis GO:0014013 23 10 0,000 7,612E-03 0,0198634 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 7,612E-03 0,01984187 ! alpha-beta T cell activation GO:0046631 23 10 0,000 7,612E-03 0,0198204 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 7,612E-03 0,01979897 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 7,612E-03 0,01977759 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 7,612E-03 0,01975626 ! blastoderm segmentation GO:0007350 18 10 0,000 7,612E-03 0,01973497 ! response to dsRNA GO:0043331 20 10 0,000 7,612E-03 0,01971372 ! DNA ligation GO:0006266 19 10 0,000 7,612E-03 0,01969253 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 7,612E-03 0,01967138 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 7,612E-03 0,01965027 ! melanosome localization GO:0032400 16 10 0,000 7,612E-03 0,01962921 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 7,612E-03 0,01960819 ! regulation of B cell differentiation GO:0045577 19 10 0,000 7,612E-03 0,01958722 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 7,612E-03 0,01956629 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 7,612E-03 0,01954541 ! mRNA cleavage GO:0006379 17 10 0,000 7,612E-03 0,01952457 ! protein sumoylation GO:0016925 15 10 0,000 7,612E-03 0,01950378 ! hindbrain morphogenesis GO:0021575 19 10 0,000 7,612E-03 0,01948303 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 7,612E-03 0,01946233 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 7,612E-03 0,01944167 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 7,612E-03 0,01942105 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 7,612E-03 0,01940048 ! salivary gland development GO:0007431 27 10 0,000 7,612E-03 0,01937995 ! prophase GO:0051324 15 10 0,000 7,612E-03 0,01935946 ! negative regulation of neurological system process GO:0031645 19 10 0,000 7,612E-03 0,01933902 ! apical protein localization GO:0045176 15 10 0,000 7,612E-03 0,01931862 ! ubiquinone metabolic process GO:0006743 15 10 0,000 7,612E-03 0,01929826 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 7,612E-03 0,01927795 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 7,612E-03 0,01925768 ! midbrain development GO:0030901 13 10 0,000 7,612E-03 0,01923745 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 7,612E-03 0,01921726 ! methionine biosynthetic process GO:0009086 19 10 0,000 7,612E-03 0,01919712 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 7,612E-03 0,01917702 ! quaternary ammonium group transport GO:0015697 21 10 0,000 7,612E-03 0,01915696 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 7,612E-03 0,01913694 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 7,612E-03 0,01911696 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 7,612E-03 0,01909703 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 7,612E-03 0,01907714 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 7,612E-03 0,01905728 ! oocyte development GO:0048599 17 10 0,000 7,612E-03 0,01903747 ! establishment of pigment granule localization GO:0051905 18 10 0,000 7,612E-03 0,01901771 ! blastocyst formation GO:0001825 17 10 0,000 7,612E-03 0,01899798 ! cerebellar cortex development GO:0021695 15 10 0,000 7,612E-03 0,01897829 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 7,612E-03 0,01895864 ! activation of innate immune response GO:0002218 12 10 0,000 7,612E-03 0,01893904 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 7,612E-03 0,01891947 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 7,612E-03 0,01889995 ! response to nicotine GO:0035094 20 10 0,000 7,612E-03 0,01888046 ! establishment of cell polarity GO:0030010 16 10 0,000 7,612E-03 0,01886102 ! negative regulation of immune effector process GO:0002698 20 10 0,000 7,612E-03 0,01884162 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 7,612E-03 0,01882225 ! localization within membrane GO:0051668 20 10 0,000 7,612E-03 0,01880293 ! negative regulation of muscle development GO:0048635 20 11 0,000 8,37E-03 0,02065447 ! respiratory burst GO:0045730 17 11 0,000 8,37E-03 0,0206333 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 8,37E-03 0,02061218 ! neuron fate specification GO:0048665 17 11 0,000 8,37E-03 0,02059111 ! telencephalon cell migration GO:0022029 20 11 0,000 8,37E-03 0,02057008 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 8,37E-03 0,02054909 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 8,37E-03 0,02052814 ! thyroid gland development GO:0030878 26 11 0,000 8,37E-03 0,02050723 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 8,37E-03 0,02048637 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 8,37E-03 0,02046555 ! Golgi vesicle budding GO:0048194 22 11 0,000 8,37E-03 0,02044478 ! response to pain GO:0048265 24 11 0,000 8,37E-03 0,02042404 ! detection of mechanical stimulus GO:0050982 22 11 0,000 8,37E-03 0,02040335 ! T cell proliferation GO:0042098 26 11 0,000 8,37E-03 0,0203827 ! blood vessel remodeling GO:0001974 29 11 0,000 8,37E-03 0,02036209 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 8,37E-03 0,02034152 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 8,37E-03 0,02032099 ! bone resorption GO:0045453 16 11 0,000 8,37E-03 0,02030051 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 8,37E-03 0,02028006 ! ventral spinal cord development GO:0021517 21 11 0,000 8,37E-03 0,02025966 ! negative regulation of proteolysis GO:0045861 25 11 0,000 8,37E-03 0,0202393 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 8,37E-03 0,02021898 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 8,37E-03 0,0201987 ! melanocyte differentiation GO:0030318 21 11 0,000 8,37E-03 0,02017846 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 8,37E-03 0,02015826 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 8,37E-03 0,0201381 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 8,37E-03 0,02011799 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 8,37E-03 0,02009791 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 8,37E-03 0,02007787 ! lipid digestion GO:0044241 18 11 0,000 8,37E-03 0,02005787 ! substrate-bound cell migration GO:0006929 13 11 0,000 8,37E-03 0,02003791 ! UV protection GO:0009650 19 11 0,000 8,37E-03 0,020018 ! adult heart development GO:0007512 14 11 0,000 8,37E-03 0,01999812 ! chondrocyte differentiation GO:0002062 24 11 0,000 8,37E-03 0,01997828 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 8,37E-03 0,01995848 ! temperature homeostasis GO:0001659 17 11 0,000 8,37E-03 0,01993872 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 8,37E-03 0,01991899 ! negative regulation of ossification GO:0030279 26 11 0,000 8,37E-03 0,01989931 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 8,37E-03 0,01987967 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 8,37E-03 0,01986006 ! regulation of organ growth GO:0046620 13 11 0,000 8,37E-03 0,0198405 ! pigment granule localization GO:0051875 20 11 0,000 8,37E-03 0,01982097 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 8,37E-03 0,01980148 ! vasoconstriction GO:0042310 18 11 0,000 8,37E-03 0,01978203 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 8,37E-03 0,01976261 ! embryonic axis specification GO:0000578 18 11 0,000 8,37E-03 0,01974324 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 8,37E-03 0,0197239 ! snRNA metabolic process GO:0016073 24 11 0,000 8,37E-03 0,0197046 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 8,37E-03 0,01968534 ! nitric oxide metabolic process GO:0046209 15 11 0,000 8,37E-03 0,01966612 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 8,37E-03 0,01964693 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 8,37E-03 0,01962778 ! zymogen activation GO:0031638 15 11 0,000 8,37E-03 0,01960867 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 8,37E-03 0,0195896 ! neuroblast proliferation GO:0007405 24 11 0,000 8,37E-03 0,01957056 ! nucleosome positioning GO:0016584 15 11 0,000 8,37E-03 0,01955156 ! regulation of isotype switching GO:0045191 22 11 0,000 8,37E-03 0,01953259 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 8,37E-03 0,01951367 ! glutathione biosynthetic process GO:0006750 13 11 0,000 8,37E-03 0,01949478 ! regulation of leukocyte migration GO:0002685 26 11 0,000 8,37E-03 0,01947592 ! acid secretion GO:0046717 18 11 0,000 8,37E-03 0,01945711 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 8,37E-03 0,01943832 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 8,37E-03 0,01941958 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 8,37E-03 0,01940087 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 8,37E-03 0,0193822 ! oocyte differentiation GO:0009994 18 11 0,000 8,37E-03 0,01936356 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 8,37E-03 0,01934496 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 8,37E-03 0,0193264 ! cholesterol efflux GO:0033344 19 11 0,000 8,37E-03 0,01930787 ! anterior/posterior axis specification GO:0009948 18 11 0,000 8,37E-03 0,01928937 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 8,37E-03 0,01927091 ! negative regulation of glucose import GO:0046325 17 11 0,000 8,37E-03 0,01925249 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 8,37E-03 0,0192341 ! embryonic gut development GO:0048566 15 11 0,000 8,37E-03 0,01921575 ! regulation of organic acid transport GO:0032890 18 11 0,000 8,37E-03 0,01919743 ! cardiac cell differentiation GO:0035051 31 11 0,000 8,37E-03 0,01917915 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 8,37E-03 0,0191609 ! defense response to fungus GO:0050832 13 11 0,000 8,37E-03 0,01914268 ! developmental induction GO:0031128 19 11 0,000 8,37E-03 0,01912451 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 8,37E-03 0,01910636 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 8,37E-03 0,01908825 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 8,37E-03 0,01907017 ! sequestering of metal ion GO:0051238 14 11 0,000 8,37E-03 0,01905213 ! lamellipodium assembly GO:0030032 20 11 0,000 8,37E-03 0,01903412 ! regulation of embryonic development GO:0045995 27 11 0,000 8,37E-03 0,01901615 ! nucleus localization GO:0051647 19 11 0,000 8,37E-03 0,01899821 ! regulation of synapse organization GO:0050807 17 11 0,000 8,37E-03 0,01898031 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 9,128E-03 0,02067874 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 9,128E-03 0,02065929 ! positive regulation of blood pressure GO:0045777 17 12 0,000 9,128E-03 0,02063987 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 9,128E-03 0,02062049 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 9,128E-03 0,02060115 ! virus-host interaction GO:0019048 29 12 0,000 9,128E-03 0,02058184 ! regulation of B cell proliferation GO:0030888 20 12 0,000 9,128E-03 0,02056257 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 9,128E-03 0,02054333 ! cartilage condensation GO:0001502 20 12 0,000 9,128E-03 0,02052413 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 9,128E-03 0,02050497 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 9,128E-03 0,02048584 ! protein complex disassembly GO:0043241 27 12 0,000 9,128E-03 0,02046675 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 9,128E-03 0,0204477 ! regulation of cell projection assembly GO:0060491 30 12 0,000 9,128E-03 0,02042867 ! hippocampus development GO:0021766 26 12 0,000 9,128E-03 0,02040969 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 9,128E-03 0,02039074 ! cytokine biosynthetic process GO:0042089 21 12 0,000 9,128E-03 0,02037182 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 9,128E-03 0,02035294 ! positive regulation of cell growth GO:0030307 22 12 0,000 9,128E-03 0,0203341 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 9,128E-03 0,02031529 ! regulation of exit from mitosis GO:0007096 17 12 0,000 9,128E-03 0,02029651 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 9,128E-03 0,02027777 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 9,128E-03 0,02025906 ! drug transport GO:0015893 16 12 0,000 9,128E-03 0,02024039 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 9,128E-03 0,02022175 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 9,128E-03 0,02020315 ! tyrosine metabolic process GO:0006570 16 12 0,000 9,128E-03 0,02018458 ! polyamine metabolic process GO:0006595 17 12 0,000 9,128E-03 0,02016605 ! focal adhesion formation GO:0048041 35 12 0,000 9,128E-03 0,02014755 ! mitotic spindle organization GO:0007052 21 12 0,000 9,128E-03 0,02012908 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 9,128E-03 0,02011065 ! forebrain cell migration GO:0021885 21 12 0,000 9,128E-03 0,02009225 ! asymmetric protein localization GO:0008105 20 12 0,000 9,128E-03 0,02007388 ! membrane protein proteolysis GO:0033619 25 12 0,000 9,128E-03 0,02005555 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 9,128E-03 0,02003725 ! entry into host cell GO:0030260 32 12 0,000 9,128E-03 0,02001898 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 9,128E-03 0,02000075 ! monoamine transport GO:0015844 18 12 0,000 9,128E-03 0,01998255 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 9,128E-03 0,01996439 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 9,128E-03 0,01994625 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 9,128E-03 0,01992815 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 9,128E-03 0,01991009 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 9,128E-03 0,01989205 ! protein targeting to peroxisome GO:0006625 23 12 0,000 9,128E-03 0,01987405 ! protein homotetramerization GO:0051289 21 12 0,000 9,128E-03 0,01985608 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 9,128E-03 0,01983814 ! regulation of phagocytosis GO:0050764 16 12 0,000 9,128E-03 0,01982024 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 9,128E-03 0,01980237 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 9,128E-03 0,01978453 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 9,128E-03 0,01976672 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 9,128E-03 0,01974894 ! cranial nerve development GO:0021545 20 12 0,000 9,128E-03 0,0197312 ! fucose catabolic process GO:0019317 22 12 0,000 9,128E-03 0,01971349 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 9,128E-03 0,01969581 ! histone acetylation GO:0016573 26 12 0,000 9,128E-03 0,01967816 ! histone methylation GO:0016571 26 12 0,000 9,128E-03 0,01966054 ! mRNA polyadenylation GO:0006378 23 12 0,000 9,128E-03 0,01964296 ! autonomic nervous system development GO:0048483 24 12 0,000 9,128E-03 0,0196254 ! gland morphogenesis GO:0022612 29 12 0,000 9,128E-03 0,01960788 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 9,128E-03 0,01959039 ! peptidyl-lysine modification GO:0018205 21 12 0,000 9,128E-03 0,01957293 ! T cell homeostasis GO:0043029 25 12 0,000 9,128E-03 0,0195555 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 9,128E-03 0,0195381 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 9,128E-03 0,01952073 ! spleen development GO:0048536 22 12 0,000 9,128E-03 0,0195034 ! digestive tract morphogenesis GO:0048546 26 12 0,000 9,128E-03 0,01948609 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 9,128E-03 0,01946882 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 9,128E-03 0,01945157 ! regulation of RNA splicing GO:0043484 20 12 0,000 9,128E-03 0,01943436 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 9,128E-03 0,01941717 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 9,128E-03 0,01940002 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 9,128E-03 0,0193829 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 9,128E-03 0,01936581 ! response to cold GO:0009409 17 12 0,000 9,128E-03 0,01934874 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 9,128E-03 0,01933171 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 9,128E-03 0,01931471 ! cGMP metabolic process GO:0046068 18 13 0,000 9,885E-03 0,02089825 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 9,885E-03 0,02087991 ! regulation of chemokine production GO:0032642 18 13 0,000 9,885E-03 0,02086159 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 9,885E-03 0,02084331 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 9,885E-03 0,02082506 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 9,885E-03 0,02080684 ! lipid localization GO:0010876 28 13 0,000 9,885E-03 0,02078865 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 9,885E-03 0,02077049 ! organelle fusion GO:0048284 32 13 0,000 9,885E-03 0,02075237 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 9,885E-03 0,02073427 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 9,885E-03 0,02071621 ! pseudouridine synthesis GO:0001522 17 13 0,000 9,885E-03 0,02069818 ! endocrine pancreas development GO:0031018 22 13 0,000 9,885E-03 0,02068019 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 9,885E-03 0,02066222 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 9,885E-03 0,02064428 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 9,885E-03 0,02062638 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 9,885E-03 0,0206085 ! methionine metabolic process GO:0006555 27 13 0,000 9,885E-03 0,02059066 ! plasma membrane organization GO:0007009 24 13 0,000 9,885E-03 0,02057285 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 9,885E-03 0,02055507 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 9,885E-03 0,02053732 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 9,885E-03 0,0205196 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 9,885E-03 0,02050191 ! cell-cell junction assembly GO:0007043 27 13 0,000 9,885E-03 0,02048425 ! response to X-ray GO:0010165 25 13 0,000 9,885E-03 0,02046662 ! cytokine metabolic process GO:0042107 22 13 0,000 9,885E-03 0,02044902 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 9,885E-03 0,02043145 ! exocrine system development GO:0035272 32 13 0,000 9,885E-03 0,02041392 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 9,885E-03 0,02039641 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 9,885E-03 0,02037893 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 9,885E-03 0,02036148 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 9,885E-03 0,02034407 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 9,885E-03 0,02032668 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 9,885E-03 0,02030932 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 9,885E-03 0,02029199 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 9,885E-03 0,02027469 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 9,885E-03 0,02025742 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 9,885E-03 0,02024018 ! regulation of cellular pH GO:0030641 22 13 0,000 9,885E-03 0,02022297 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 9,885E-03 0,02020579 ! ribosome assembly GO:0042255 17 13 0,000 9,885E-03 0,02018864 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 9,885E-03 0,02017151 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 9,885E-03 0,02015442 ! chromatin silencing GO:0006342 26 13 0,000 9,885E-03 0,02013735 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 9,885E-03 0,02012032 ! regulation of epidermis development GO:0045682 19 13 0,000 9,885E-03 0,02010331 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 9,885E-03 0,02008633 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 9,885E-03 0,02006938 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 9,885E-03 0,02005246 ! regulation of mRNA stability GO:0043488 31 13 0,000 9,885E-03 0,02003556 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 9,885E-03 0,0200187 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 9,885E-03 0,02000186 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 9,885E-03 0,01998505 ! mRNA 3'-end processing GO:0031124 24 13 0,000 9,885E-03 0,01996827 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 9,885E-03 0,01995152 ! embryonic placenta development GO:0001892 23 13 0,000 9,885E-03 0,0199348 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 9,885E-03 0,0199181 ! insulin secretion GO:0030073 23 13 0,000 9,885E-03 0,01990143 ! actin filament polymerization GO:0030041 24 13 0,000 9,885E-03 0,01988479 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 9,885E-03 0,01986818 ! acrosome reaction GO:0007340 18 13 0,000 9,885E-03 0,0198516 ! rRNA transcription GO:0009303 25 14 0,000 0,01064101 0,02135302 ! lactation GO:0007595 26 14 0,000 0,01064101 0,02133523 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,01064101 0,02131746 ! reproductive cellular process GO:0048610 20 14 0,000 0,01064101 0,02129973 ! tRNA modification GO:0006400 20 14 0,000 0,01064101 0,02128202 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,01064101 0,02126434 ! regulation of S phase GO:0033261 23 14 0,000 0,01064101 0,0212467 ! water transport GO:0006833 21 14 0,000 0,01064101 0,02122908 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,01064101 0,02121149 ! non-recombinational repair GO:0000726 25 14 0,000 0,01064101 0,02119393 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,01064101 0,0211764 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,01064101 0,0211589 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,01064101 0,02114143 ! RNA polyadenylation GO:0043631 30 14 0,000 0,01064101 0,02112399 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,01064101 0,02110657 ! palate development GO:0060021 31 14 0,000 0,01064101 0,02108918 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,01064101 0,02107183 ! regulated secretory pathway GO:0045055 23 14 0,000 0,01064101 0,0210545 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,01064101 0,0210372 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,01064101 0,02101993 ! arginine metabolic process GO:0006525 17 14 0,000 0,01064101 0,02100268 ! regulation of heart rate GO:0002027 24 14 0,000 0,01064101 0,02098547 ! organic alcohol transport GO:0015850 29 14 0,000 0,01064101 0,02096828 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,01064101 0,02095112 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,01064101 0,02093399 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,01064101 0,02091689 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,01064101 0,02089981 ! neutral amino acid transport GO:0015804 26 14 0,000 0,01064101 0,02088277 ! L-amino acid transport GO:0015807 30 14 0,000 0,01064101 0,02086575 ! bone mineralization GO:0030282 17 14 0,000 0,01064101 0,02084875 ! stem cell development GO:0048864 43 14 0,000 0,01064101 0,02083179 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,01064101 0,02081485 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,01064101 0,02079795 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,01064101 0,02078106 ! cerebellum development GO:0021549 21 14 0,000 0,01064101 0,02076421 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,01064101 0,02074738 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,01064101 0,02073058 ! response to gamma radiation GO:0010332 28 14 0,000 0,01064101 0,02071381 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,01064101 0,02069707 ! cofactor transport GO:0051181 26 14 0,000 0,01064101 0,02068035 ! NADP metabolic process GO:0006739 24 14 0,000 0,01064101 0,02066366 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,01064101 0,02064699 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,01064101 0,02063035 ! intestinal absorption GO:0050892 25 14 0,000 0,01064101 0,02061374 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,01064101 0,02059716 ! oxygen transport GO:0015671 21 14 0,000 0,01064101 0,0205806 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,01064101 0,02056407 ! male genitalia development GO:0030539 24 14 0,000 0,01064101 0,02054757 ! regulation of RNA stability GO:0043487 32 14 0,000 0,01064101 0,02053109 ! regulation of axon extension GO:0030516 37 14 0,000 0,01064101 0,02051464 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,01064101 0,02049821 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,01064101 0,02048182 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,01139692 0,02191926 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,01139692 0,02190176 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,01139692 0,02188428 ! superoxide anion generation GO:0042554 20 15 0,000 0,01139692 0,02186682 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,01139692 0,0218494 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,01139692 0,021832 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,01139692 0,02181464 ! copper ion transport GO:0006825 20 15 0,000 0,01139692 0,0217973 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,01139692 0,02177998 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,01139692 0,0217627 ! sulfate transport GO:0008272 23 15 0,000 0,01139692 0,02174544 ! response to cAMP GO:0051591 22 15 0,000 0,01139692 0,02172821 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,01139692 0,021711 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,01139692 0,02169383 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,01139692 0,02167668 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,01139692 0,02165956 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,01139692 0,02164246 ! response to hexose stimulus GO:0009746 22 15 0,000 0,01139692 0,02162539 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,01139692 0,02160835 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,01139692 0,02159134 ! pituitary gland development GO:0021983 29 15 0,000 0,01139692 0,02157435 ! vesicle coating GO:0006901 33 15 0,000 0,01139692 0,02155739 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,01139692 0,02154045 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,01139692 0,02152355 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,01139692 0,02150666 ! regulation of exocytosis GO:0017157 22 15 0,000 0,01139692 0,02148981 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,01139692 0,02147298 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,01139692 0,02145618 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,01139692 0,0214394 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,01139692 0,02142265 ! regulation of vasodilation GO:0042312 26 15 0,000 0,01139692 0,02140593 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,01139692 0,02138923 ! histone deacetylation GO:0016575 20 15 0,000 0,01139692 0,02137256 ! mRNA splice site selection GO:0006376 38 15 0,000 0,01139692 0,02135592 ! tissue regeneration GO:0042246 26 15 0,000 0,01139692 0,0213393 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,01139692 0,0213227 ! water homeostasis GO:0030104 27 15 0,000 0,01139692 0,02130614 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,01139692 0,02128959 ! muscle maintenance GO:0046716 26 15 0,000 0,01139692 0,02127308 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,01139692 0,02125659 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,01139692 0,02124012 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,01139692 0,02122368 ! dopamine metabolic process GO:0042417 35 15 0,000 0,01139692 0,02120727 ! heme biosynthetic process GO:0006783 29 15 0,000 0,01139692 0,02119088 ! cell killing GO:0001906 29 15 0,000 0,01139692 0,02117452 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,01139692 0,02115818 ! detection of bacterium GO:0016045 18 15 0,000 0,01139692 0,02114186 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,01139692 0,02112558 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,01139692 0,02110931 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,01139692 0,02109308 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,01139692 0,02107686 ! peptide hormone processing GO:0016486 23 15 0,000 0,01139692 0,02106067 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,01215228 0,02243929 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,01215228 0,02242208 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,01215228 0,0224049 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,01215228 0,02238775 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,01215228 0,02237062 ! bone remodeling GO:0046849 27 16 0,000 0,01215228 0,02235351 ! filopodium assembly GO:0046847 32 16 0,000 0,01215228 0,02233644 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,01215228 0,02231939 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,01215228 0,02230236 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,01215228 0,02228536 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,01215228 0,02226839 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,01215228 0,02225144 ! startle response GO:0001964 28 16 0,000 0,01215228 0,02223452 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,01215228 0,02221763 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,01215228 0,02220076 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,01215228 0,02218391 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,01215228 0,02216709 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,01215228 0,0221503 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,01215228 0,02213353 ! protein polyubiquitination GO:0000209 34 16 0,000 0,01215228 0,02211679 ! glutamate metabolic process GO:0006536 22 16 0,000 0,01215228 0,02210007 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,01215228 0,02208338 ! response to osmotic stress GO:0006970 25 16 0,000 0,01215228 0,02206671 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,01215228 0,02205007 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,01215228 0,02203346 ! fructose metabolic process GO:0006000 25 16 0,000 0,01215228 0,02201686 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,01215228 0,0220003 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 32 16 0,000 0,01215228 0,02198376 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,01215228 0,02196724 ! negative regulation of immune response GO:0050777 35 16 0,000 0,01215228 0,02195075 ! axon cargo transport GO:0008088 43 16 0,000 0,01215228 0,02193428 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,01215228 0,02191784 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,01215228 0,02190142 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,01215228 0,02188503 ! DNA replication initiation GO:0006270 27 16 0,000 0,01215228 0,02186866 ! neuron recognition GO:0008038 35 16 0,000 0,01215228 0,02185231 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,01215228 0,02183599 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,01215228 0,0218197 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,01215228 0,02180343 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,01215228 0,02178718 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,01215228 0,02177096 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,01215228 0,02175476 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,01215228 0,02173858 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,01215228 0,02172243 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,01215228 0,02170631 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,01215228 0,0216902 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,01215228 0,02167413 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,01215228 0,02165807 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,01215228 0,02164204 ! defense response to virus GO:0051607 37 16 0,000 0,01215228 0,02162603 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,01290709 0,0229523 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,01290709 0,02293535 ! metencephalon development GO:0022037 30 17 0,000 0,01290709 0,02291842 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,01290709 0,02290152 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,01290709 0,02288465 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,01290709 0,02286779 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,01290709 0,02285097 ! signal complex assembly GO:0007172 41 17 0,000 0,01290709 0,02283417 ! endothelial cell migration GO:0043542 28 17 0,000 0,01290709 0,02281739 ! inositol metabolic process GO:0006020 28 17 0,000 0,01290709 0,02280064 ! gene silencing by RNA GO:0031047 36 17 0,000 0,01290709 0,02278391 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,01290709 0,0227672 ! glial cell development GO:0021782 27 17 0,000 0,01290709 0,02275052 ! limbic system development GO:0021761 36 17 0,000 0,01290709 0,02273387 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,01290709 0,02271724 ! adult walking behavior GO:0007628 33 17 0,000 0,01290709 0,02270063 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,01290709 0,02268405 ! heart looping GO:0001947 30 17 0,000 0,01290709 0,02266749 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,01290709 0,02265096 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,01290709 0,02263445 ! myoblast differentiation GO:0045445 45 17 0,000 0,01290709 0,02261796 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,01290709 0,0226015 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,01290709 0,02258507 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,01290709 0,02256865 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,01290709 0,02255226 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,01290709 0,0225359 ! glycine metabolic process GO:0006544 28 17 0,000 0,01290709 0,02251955 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,01290709 0,02250324 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,01290709 0,02248694 ! NAD metabolic process GO:0019674 29 17 0,000 0,01290709 0,02247067 ! membrane budding GO:0006900 37 17 0,000 0,01290709 0,02245442 ! DNA integration GO:0015074 29 17 0,000 0,01290709 0,0224382 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,01290709 0,022422 ! regulation of protein binding GO:0043393 33 17 0,000 0,01290709 0,02240582 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,01290709 0,02238967 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,01290709 0,02237353 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,01290709 0,02235743 ! genitalia development GO:0048806 30 17 0,000 0,01290709 0,02234134 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,01290709 0,02232528 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,01290709 0,02230924 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,01290709 0,02229323 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,01290709 0,02227723 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,01290709 0,02226127 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,01290709 0,02224532 ! steroid catabolic process GO:0006706 31 17 0,000 0,01290709 0,0222294 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,01290709 0,02221349 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,01290709 0,02219762 ! gas transport GO:0015669 25 17 0,000 0,01290709 0,02218176 ! organic cation transport GO:0015695 31 17 0,000 0,01290709 0,02216593 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,01290709 0,02215012 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,01290709 0,02213433 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,01290709 0,02211857 ! microspike assembly GO:0030035 36 17 0,000 0,01290709 0,02210282 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,01290709 0,0220871 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,01290709 0,0220714 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,01366135 0,02334461 ! neuron maturation GO:0042551 42 18 0,000 0,01366135 0,02332804 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,01366135 0,0233115 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,01366135 0,02329497 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,01366135 0,02327848 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,01366135 0,023262 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,01366135 0,02324555 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,01366135 0,02322912 ! memory GO:0007613 31 18 0,000 0,01366135 0,02321272 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,01366135 0,02319634 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,01366135 0,02317998 ! patterning of blood vessels GO:0001569 39 18 0,000 0,01366135 0,02316364 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,01366135 0,02314733 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,01366135 0,02313104 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,01366135 0,02311477 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,01366135 0,02309853 ! glutamine metabolic process GO:0006541 29 18 0,000 0,01366135 0,02308231 ! response to retinoic acid GO:0032526 26 18 0,000 0,01366135 0,02306611 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,01366135 0,02304994 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,01366135 0,02303378 ! response to fungus GO:0009620 21 18 0,000 0,01366135 0,02301765 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,01366135 0,02300155 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,01366135 0,02298546 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,01366135 0,0229694 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,01366135 0,02295336 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,01366135 0,02293734 ! vitamin transport GO:0051180 27 18 0,000 0,01366135 0,02292134 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,01366135 0,02290537 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,01366135 0,02288942 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,01366135 0,02287349 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,01366135 0,02285759 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,01366135 0,0228417 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,01366135 0,02282584 ! nerve development GO:0021675 28 18 0,000 0,01366135 0,02281 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,01366135 0,02279418 ! protein secretion GO:0009306 39 19 0,000 0,01441506 0,02403508 ! positive regulation of translation GO:0045727 30 19 0,000 0,01441506 0,02401844 ! negative regulation of defense response GO:0031348 25 19 0,000 0,01441506 0,02400182 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,01441506 0,02398522 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,01441506 0,02396864 ! skin development GO:0043588 36 19 0,000 0,01441506 0,02395209 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,01441506 0,02393556 ! lipid phosphorylation GO:0046834 35 19 0,000 0,01441506 0,02391905 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,01441506 0,02390257 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,01441506 0,0238861 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,01441506 0,02386967 ! bile acid metabolic process GO:0008206 29 19 0,000 0,01441506 0,02385325 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,01441506 0,02383685 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,01441506 0,02382048 ! cerebral cortex development GO:0021987 36 19 0,000 0,01441506 0,02380413 ! pigmentation during development GO:0048066 41 19 0,000 0,01441506 0,02378781 ! response to vitamin A GO:0033189 27 19 0,000 0,01441506 0,0237715 ! heme metabolic process GO:0042168 36 19 0,000 0,01441506 0,02375522 ! actin filament bundle formation GO:0051017 42 19 0,000 0,01441506 0,02373896 ! neuromuscular junction development GO:0007528 34 19 0,000 0,01441506 0,02372273 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,01441506 0,02370651 ! plasma membrane fusion GO:0045026 28 19 0,000 0,01441506 0,02369032 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,01441506 0,02367415 ! peptide cross-linking GO:0018149 37 19 0,000 0,01441506 0,023658 ! protein export from nucleus GO:0006611 36 19 0,000 0,01441506 0,02364187 ! heart process GO:0003015 30 19 0,000 0,01441506 0,02362577 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,01441506 0,02360968 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,01441506 0,02359362 ! visual learning GO:0008542 36 19 0,000 0,01441506 0,02357758 ! cellular pigmentation GO:0033059 36 19 0,000 0,01441506 0,02356157 ! G1 phase GO:0051318 40 19 0,000 0,01441506 0,02354557 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,01441506 0,0235296 ! cell-cell junction organization GO:0045216 35 19 0,000 0,01441506 0,02351364 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,01441506 0,02349771 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,01441506 0,0234818 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,01441506 0,02346592 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,01441506 0,02345005 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,01441506 0,02343421 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,01441506 0,02341838 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,01441506 0,02340258 ! cilium assembly GO:0042384 37 19 0,000 0,01441506 0,0233868 ! peptide hormone secretion GO:0030072 31 19 0,000 0,01441506 0,02337104 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,01516821 0,02457557 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,01516821 0,02455903 ! positive regulation of ossification GO:0045778 47 20 0,000 0,01516821 0,02454251 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,01516821 0,02452602 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,01516821 0,02450955 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,01516821 0,0244931 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,01516821 0,02447667 ! cAMP metabolic process GO:0046058 36 20 0,000 0,01516821 0,02446026 ! response to vitamin GO:0033273 31 20 0,000 0,01516821 0,02444388 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,01516821 0,02442752 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,01516821 0,02441118 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,01516821 0,02439486 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,01516821 0,02437857 ! response to alkaloid GO:0043279 38 20 0,000 0,01516821 0,02436229 ! retinoid metabolic process GO:0001523 32 20 0,000 0,01516821 0,02434604 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,01516821 0,02432981 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,01516821 0,0243136 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,01516821 0,02429741 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,01516821 0,02428125 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,01516821 0,0242651 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,01516821 0,02424898 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,01516821 0,02423288 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,01516821 0,0242168 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,01516821 0,02420074 ! body fluid secretion GO:0007589 31 20 0,000 0,01516821 0,0241847 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,01516821 0,02416869 ! peptide secretion GO:0002790 35 20 0,000 0,01516821 0,02415269 ! stem cell differentiation GO:0048863 53 20 0,000 0,01516821 0,02413672 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,01516821 0,02412076 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,01516821 0,02410483 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,01516821 0,02408892 ! sensory perception of pain GO:0019233 30 20 0,000 0,01516821 0,02407303 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,01516821 0,02405716 ! diencephalon development GO:0021536 34 20 0,000 0,01516821 0,02404131 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,01516821 0,02402549 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,01516821 0,02400968 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,01516821 0,0239939 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,01516821 0,02397813 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,01516821 0,02396239 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,01516821 0,02394666 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,01516821 0,02393096 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,01516821 0,02391528 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,01516821 0,02389962 ! regulation of glucose import GO:0046324 29 20 0,000 0,01516821 0,02388398 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,01516821 0,02386835 ! actin filament-based movement GO:0030048 43 20 0,000 0,01516821 0,02385275 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,01516821 0,02383717 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,01516821 0,02382162 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,01516821 0,02380608 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,01516821 0,02379056 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,01516821 0,02377506 ! regulation of cell killing GO:0031341 42 21 0,000 0,01592081 0,02493846 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,01592081 0,02492224 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,01592081 0,02490603 ! hormone secretion GO:0046879 38 21 0,000 0,01592081 0,02488985 ! glycerol metabolic process GO:0006071 34 21 0,000 0,01592081 0,02487369 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,01592081 0,02485755 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,01592081 0,02484143 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,01592081 0,02482533 ! axis specification GO:0009798 38 21 0,000 0,01592081 0,02480925 ! ovarian follicle development GO:0001541 35 21 0,000 0,01592081 0,02479319 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,01592081 0,02477715 ! smooth muscle contraction GO:0006939 46 21 0,000 0,01592081 0,02476114 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,01592081 0,02474514 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,01592081 0,02472917 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,01592081 0,02471321 ! cell aging GO:0007569 44 21 0,000 0,01592081 0,02469728 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,01592081 0,02468137 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,01592081 0,02466547 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,01592081 0,0246496 ! cytolysis GO:0019835 24 21 0,000 0,01592081 0,02463375 ! vasodilation GO:0042311 39 21 0,000 0,01592081 0,02461792 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,01592081 0,02460211 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,01592081 0,02458632 ! oogenesis GO:0048477 36 21 0,000 0,01592081 0,02457055 ! DNA modification GO:0006304 34 21 0,000 0,01592081 0,0245548 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,01592081 0,02453906 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,01592081 0,02452335 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,01592081 0,02450766 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,01592081 0,024492 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,01592081 0,02447635 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,01592081 0,02446072 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,01592081 0,02444511 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,01592081 0,02442952 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,01592081 0,02441395 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,01592081 0,0243984 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,01592081 0,02438286 ! collagen catabolic process GO:0030574 28 21 0,000 0,01592081 0,02436735 ! sperm-egg recognition GO:0035036 21 21 0,000 0,01592081 0,02435186 ! gut development GO:0048565 39 21 0,000 0,01592081 0,02433639 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,01667287 0,02546979 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,01667287 0,02545363 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,01667287 0,02543749 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,01667287 0,02542137 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,01667287 0,02540527 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,01667287 0,02538919 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,01667287 0,02537313 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,01667287 0,02535709 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,01667287 0,02534108 ! regeneration GO:0031099 41 22 0,000 0,01667287 0,02532508 ! keratinization GO:0031424 28 22 0,000 0,01667287 0,0253091 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,01667287 0,02529314 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,01667287 0,0252772 ! sensory perception of taste GO:0050909 28 22 0,000 0,01667287 0,02526129 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,01667287 0,02524539 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,01667287 0,02522951 ! vacuolar transport GO:0007034 36 22 0,000 0,01667287 0,02521365 ! lysosome organization GO:0007040 41 22 0,000 0,01667287 0,02519782 ! central nervous system neuron development GO:0021954 46 22 0,000 0,01667287 0,025182 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,01667287 0,0251662 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,01667287 0,02515042 ! fucose metabolic process GO:0006004 39 22 0,000 0,01667287 0,02513466 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,01667287 0,02511892 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,01667287 0,02510321 ! ureteric bud development GO:0001657 43 22 0,000 0,01667287 0,02508751 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,01667287 0,02507183 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,01667287 0,02505617 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,01667287 0,02504053 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,01667287 0,0250249 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,01667287 0,0250093 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,01667287 0,02499372 ! sarcomere organization GO:0045214 30 22 0,000 0,01667287 0,02497816 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,01667287 0,02496262 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,01667287 0,02494709 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,01667287 0,02493159 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,01667287 0,0249161 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,01667287 0,02490063 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,01667287 0,02488519 ! protein stabilization GO:0050821 39 22 0,000 0,01667287 0,02486976 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,01742437 0,02597462 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,01742437 0,02595854 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,01742437 0,02594248 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,01742437 0,02592643 ! gluconeogenesis GO:0006094 33 23 0,000 0,01742437 0,02591041 ! viral genome replication GO:0019079 41 23 0,000 0,01742437 0,02589441 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,01742437 0,02587842 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,01742437 0,02586246 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,01742437 0,02584651 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,01742437 0,02583059 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,01742437 0,02581468 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,01742437 0,0257988 ! visual behavior GO:0007632 42 23 0,000 0,01742437 0,02578293 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,01742437 0,02576708 ! response to ethanol GO:0045471 46 23 0,000 0,01742437 0,02575125 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,01742437 0,02573545 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,01742437 0,02571966 ! peroxisome organization GO:0007031 37 23 0,000 0,01742437 0,02570389 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,01742437 0,02568814 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,01742437 0,02567241 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,01742437 0,0256567 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,01742437 0,025641 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,01742437 0,02562533 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,01742437 0,02560968 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,01742437 0,02559404 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,01742437 0,02557843 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,01742437 0,02556283 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,01742437 0,02554725 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,01742437 0,02553169 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,01742437 0,02551615 ! fatty acid transport GO:0015908 44 23 0,000 0,01742437 0,02550063 ! platelet activation GO:0030168 37 23 0,000 0,01742437 0,02548513 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,01742437 0,02546965 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,01742437 0,02545418 ! hormone transport GO:0009914 40 23 0,000 0,01742437 0,02543874 ! cell-cell recognition GO:0009988 25 23 0,000 0,01742437 0,02542331 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,01742437 0,0254079 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,01742437 0,02539251 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,01742437 0,02537714 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,01742437 0,02536179 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,01742437 0,02534646 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,01817533 0,02642286 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,01817533 0,02640691 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,01817533 0,02639097 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,01817533 0,02637505 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,01817533 0,02635916 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,01817533 0,02634328 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,01817533 0,02632742 ! vesicle docking GO:0048278 47 24 0,000 0,01817533 0,02631158 ! spinal cord development GO:0021510 47 24 0,000 0,01817533 0,02629575 ! vacuole organization GO:0007033 43 24 0,000 0,01817533 0,02627995 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,01817533 0,02626417 ! digestive system process GO:0022600 39 24 0,000 0,01817533 0,0262484 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,01817533 0,02623266 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,01817533 0,02621693 ! regulation of behavior GO:0050795 43 24 0,000 0,01817533 0,02620122 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,01817533 0,02618553 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,01817533 0,02616986 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,01817533 0,02615421 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,01817533 0,02613858 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,01817533 0,02612296 ! membrane depolarization GO:0051899 39 24 0,000 0,01817533 0,02610737 ! pallium development GO:0021543 49 24 0,000 0,01817533 0,02609179 ! pentose metabolic process GO:0019321 35 24 0,000 0,01817533 0,02607623 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,01817533 0,02606069 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,01817533 0,02604517 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,01817533 0,02602967 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,01817533 0,02601418 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,01817533 0,02599872 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,01817533 0,02598327 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,01817533 0,02596784 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,01817533 0,02595243 ! regulation of amine transport GO:0051952 40 24 0,000 0,01817533 0,02593703 ! protein tetramerization GO:0051262 52 24 0,000 0,01817533 0,02592166 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,01892573 0,0269759 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,01892573 0,02695993 ! myelination GO:0042552 45 25 0,000 0,01892573 0,02694397 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,01892573 0,02692804 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,01892573 0,02691213 ! phototransduction GO:0007602 33 25 0,000 0,01892573 0,02689623 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,01892573 0,02688035 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,01892573 0,02686449 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,01892573 0,02684865 ! sperm motility GO:0030317 31 25 0,000 0,01892573 0,02683283 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,01892573 0,02681703 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,01892573 0,02680125 ! receptor metabolic process GO:0043112 46 25 0,000 0,01892573 0,02678548 ! chromosome condensation GO:0030261 45 25 0,000 0,01892573 0,02676973 ! response to starvation GO:0042594 42 25 0,000 0,01892573 0,02675401 ! osteoblast differentiation GO:0001649 60 25 0,000 0,01892573 0,0267383 ! neural crest cell development GO:0014032 54 25 0,000 0,01892573 0,0267226 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,01892573 0,02670693 ! negative regulation of cell development GO:0010721 73 25 0,000 0,01892573 0,02669128 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,01892573 0,02667564 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,01892573 0,02666002 ! interaction with host GO:0051701 62 25 0,000 0,01892573 0,02664442 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,01892573 0,02662884 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,01892573 0,02661328 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,01892573 0,02659773 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,01892573 0,0265822 ! immunoglobulin production GO:0002377 55 25 0,000 0,01892573 0,0265667 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,01892573 0,02655121 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,01892573 0,02653573 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,01892573 0,02652028 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,01892573 0,02650484 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,01892573 0,02648942 ! telomere organization GO:0032200 43 25 0,000 0,01892573 0,02647402 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,01892573 0,02645864 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,01892573 0,02644327 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,01967559 0,02747503 ! embryonic pattern specification GO:0009880 44 26 0,000 0,01967559 0,02745909 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,01967559 0,02744317 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,01967559 0,02742727 ! initiation of viral infection GO:0019059 57 26 0,000 0,01967559 0,02741139 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,01967559 0,02739553 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,01967559 0,02737968 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,01967559 0,02736386 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,01967559 0,02734805 ! molting cycle process GO:0022404 50 26 0,000 0,01967559 0,02733226 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,01967559 0,02731649 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,01967559 0,02730073 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,01967559 0,027285 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,01967559 0,02726928 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,01967559 0,02725358 GO:0051297|centrosome organization, ! insulin receptor signaling pathway GO:0008286 64 26 0,000 0,01967559 0,0272379 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,01967559 0,02722224 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,01967559 0,02720659 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,01967559 0,02719097 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,01967559 0,02717536 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,01967559 0,02715977 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,01967559 0,02714419 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,01967559 0,02712864 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,01967559 0,0271131 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,01967559 0,02709758 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,01967559 0,02708208 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,01967559 0,02706659 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,01967559 0,02705113 ! blastocyst development GO:0001824 49 26 0,000 0,01967559 0,02703568 ! leukocyte proliferation GO:0070661 52 26 0,000 0,01967559 0,02702025 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,01967559 0,02700483 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,01967559 0,02698944 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,0204249 0,02800132 ! neuron fate commitment GO:0048663 48 27 0,000 0,0204249 0,02798537 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,0204249 0,02796944 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,0204249 0,02795353 ! iron ion transport GO:0006826 59 27 0,000 0,0204249 0,02793764 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,0204249 0,02792177 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,0204249 0,02790591 ! protein amino acid acylation GO:0043543 55 27 0,000 0,0204249 0,02789007 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,0204249 0,02787425 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,0204249 0,02785845 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,0204249 0,02784267 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,0204249 0,0278269 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,0204249 0,02781116 ! autophagy GO:0006914 41 27 0,000 0,0204249 0,02779542 ! male gonad development GO:0008584 44 27 0,000 0,0204249 0,02777971 ! response to toxin GO:0009636 47 27 0,000 0,0204249 0,02776402 ! primary neural tube formation GO:0014020 51 27 0,000 0,0204249 0,02774834 ! base-excision repair GO:0006284 41 27 0,000 0,0204249 0,02773268 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,0204249 0,02771704 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,0204249 0,02770142 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,0204249 0,02768581 ! glutathione metabolic process GO:0006749 39 27 0,000 0,0204249 0,02767022 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,0204249 0,02765465 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,0204249 0,0276391 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,0204249 0,02762356 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,0204249 0,02760804 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,02117366 0,02860406 ! circadian rhythm GO:0007623 50 28 0,000 0,02117366 0,02858801 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,02117366 0,02857197 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,02117366 0,02855596 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,02117366 0,02853996 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,02117366 0,02852398 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,02117366 0,02850802 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,02117366 0,02849208 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,02117366 0,02847615 ! synaptogenesis GO:0007416 42 28 0,000 0,02117366 0,02846024 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,02117366 0,02844435 ! lipid oxidation GO:0034440 43 28 0,000 0,02117366 0,02842848 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,02117366 0,02841262 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,02117366 0,02839678 ! translational initiation GO:0006413 65 29 0,000 0,02192188 0,02938386 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,02192188 0,0293675 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,02192188 0,02935116 ! regulation of pH GO:0006885 43 29 0,000 0,02192188 0,02933484 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,02192188 0,02931853 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,02192188 0,02930224 ! catechol metabolic process GO:0009712 54 29 0,000 0,02192188 0,02928597 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,02192188 0,02926972 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,02192188 0,02925348 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,02192188 0,02923727 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,02192188 0,02922107 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,02192188 0,02920489 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,02192188 0,02918873 ! cell fate determination GO:0001709 60 29 0,000 0,02192188 0,02917258 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,02192188 0,02915646 ! detection of light stimulus GO:0009583 38 29 0,000 0,02192188 0,02914035 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 0,02192188 0,02912426 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,02192188 0,02910819 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,02192188 0,02909213 ! tissue homeostasis GO:0001894 48 29 0,000 0,02192188 0,02907609 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,02192188 0,02906007 ! phenol metabolic process GO:0018958 55 30 0,000 0,02266954 0,03003465 ! zinc ion transport GO:0006829 45 30 0,000 0,02266954 0,03001812 ! membrane docking GO:0022406 61 30 0,000 0,02266954 0,03000161 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,02266954 0,02998511 ! cell junction assembly GO:0034329 78 30 0,000 0,02266954 0,02996864 ! regulation of innate immune response GO:0045088 51 30 0,000 0,02266954 0,02995218 ! acute-phase response GO:0006953 49 30 0,000 0,02266954 0,02993574 ! myofibril assembly GO:0030239 47 30 0,000 0,02266954 0,02991932 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,02266954 0,02990292 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,02266954 0,02988653 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,02266954 0,02987016 ! phospholipid transport GO:0015914 51 30 0,000 0,02266954 0,02985381 ! ensheathment of neurons GO:0007272 57 30 0,000 0,02266954 0,02983748 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,02266954 0,02982117 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,02266954 0,02980487 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,02266954 0,0297886 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,02266954 0,02977234 ! eye morphogenesis GO:0048592 60 30 0,000 0,02266954 0,02975609 ! regulation of B cell activation GO:0050864 50 30 0,000 0,02266954 0,02973987 ! response to heat GO:0009408 50 30 0,000 0,02266954 0,02972366 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,02341666 0,03068654 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,02341666 0,03066984 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,02341666 0,03065315 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,02341666 0,03063648 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,02341666 0,03061983 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,02341666 0,0306032 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,02341666 0,03058659 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,02341666 0,03056999 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,02341666 0,03055341 ! ovulation cycle process GO:0022602 49 31 0,000 0,02341666 0,03053685 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,02341666 0,03052031 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,02341666 0,03050378 ! peptide transport GO:0015833 55 31 0,000 0,02341666 0,03048728 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,02341666 0,03047079 ! iron ion homeostasis GO:0055072 54 31 0,000 0,02341666 0,03045432 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,02341666 0,03043787 ! mesoderm formation GO:0001707 69 31 0,000 0,02341666 0,03042143 ! natural killer cell activation GO:0030101 45 31 0,000 0,02341666 0,03040501 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,02341666 0,03038861 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,02341666 0,03037223 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,02341666 0,03035587 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,02341666 0,03033952 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,02341666 0,03032319 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,02416324 0,03127313 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,02416324 0,03125632 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,02416324 0,03123952 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,02416324 0,03122274 ! cholesterol transport GO:0030301 56 32 0,000 0,02416324 0,03120598 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,02416324 0,03118924 ! spliceosome assembly GO:0000245 67 32 0,000 0,02416324 0,03117252 ! spindle organization GO:0007051 46 32 0,000 0,02416324 0,03115581 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,02416324 0,03113913 ! metanephros development GO:0001656 74 32 0,000 0,02416324 0,03112246 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,02416324 0,0311058 ! response to ionizing radiation GO:0010212 65 32 0,000 0,02416324 0,03108917 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,02416324 0,03107255 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,02416324 0,03105595 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,02416324 0,03103937 ! muscle cell development GO:0055001 49 32 0,000 0,02416324 0,03102281 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,02416324 0,03100626 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,02416324 0,03098974 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,02416324 0,03097323 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,02416324 0,03095673 ! ovulation cycle GO:0042698 51 32 0,000 0,02416324 0,03094026 ! peripheral nervous system development GO:0007422 64 32 0,000 0,02416324 0,0309238 ! BMP signaling pathway GO:0030509 64 32 0,000 0,02416324 0,03090736 ! hindbrain development GO:0030902 61 32 0,000 0,02416324 0,03089094 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,02416324 0,03087453 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,02416324 0,03085815 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,02416324 0,03084178 ! gene silencing GO:0016458 65 32 0,000 0,02416324 0,03082542 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,02490926 0,0317603 ! post-embryonic development GO:0009791 69 33 0,000 0,02490926 0,03174348 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,02490926 0,03172668 ! protein targeting to membrane GO:0006612 68 33 0,000 0,02490926 0,03170989 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,02490926 0,03169312 ! ceramide metabolic process GO:0006672 64 33 0,000 0,02490926 0,03167637 ! formation of primary germ layer GO:0001704 72 33 0,000 0,02490926 0,03165964 ! cell fate specification GO:0001708 52 33 0,000 0,02490926 0,03164292 ! sterol transport GO:0015918 57 33 0,000 0,02490926 0,03162622 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,02490926 0,03160954 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,02490926 0,03159288 ! adult locomotory behavior GO:0008344 59 33 0,000 0,02490926 0,03157623 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,02490926 0,0315596 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,02490926 0,03154299 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,02565475 0,03246992 ! glial cell differentiation GO:0010001 63 34 0,000 0,02565475 0,03245285 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,02565475 0,0324358 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,02565475 0,03241876 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,02565475 0,03240174 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,02565475 0,03238474 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,02565475 0,03236776 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,02565475 0,0323508 ! mismatch repair GO:0006298 46 34 0,000 0,02565475 0,03233385 ! spermatid development GO:0007286 63 34 0,000 0,02565475 0,03231692 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,02565475 0,03230001 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,02565475 0,03228312 ! placenta development GO:0001890 53 34 0,000 0,02565475 0,03226624 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,02565475 0,03224938 ! regulation of muscle development GO:0048634 70 35 0,000 0,02639968 0,03316848 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,02639968 0,03315117 ! negative regulation of secretion GO:0051048 63 35 0,000 0,02639968 0,03313387 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,02639968 0,0331166 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,02639968 0,03309934 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,02639968 0,0330821 ! odontogenesis GO:0042476 66 35 0,000 0,02639968 0,03306488 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,02639968 0,03304768 ! female gonad development GO:0008585 58 35 0,000 0,02639968 0,03303049 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,02639968 0,03301333 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,02639968 0,03299618 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,02639968 0,03297904 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,02639968 0,03296193 ! cytokine production GO:0001816 59 35 0,000 0,02639968 0,03294483 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,02639968 0,03292775 ! neural tube formation GO:0001841 67 35 0,000 0,02639968 0,03291069 ! vesicle localization GO:0051648 64 35 0,000 0,02639968 0,03289365 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,02714408 0,03380365 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,02714408 0,03378616 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,02714408 0,03376869 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,02714408 0,03375124 ! cell junction organization GO:0034330 86 36 0,000 0,02714408 0,0337338 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,02714408 0,03371639 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,02714408 0,03369899 ! positive regulation of cell development GO:0010720 80 36 0,000 0,02714408 0,03368161 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,02714408 0,03366425 ! regulation of proteolysis GO:0030162 72 36 0,000 0,02714408 0,03364691 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,02714408 0,03362958 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,02714408 0,03361227 ! aerobic respiration GO:0009060 55 36 0,000 0,02714408 0,03359498 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,02714408 0,03357771 ! embryonic organ development GO:0048568 57 36 0,000 0,02714408 0,03356046 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,02714408 0,03354322 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,02714408 0,033526 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,02788792 0,03442706 ! meiosis I GO:0007127 65 37 0,000 0,02788792 0,03440941 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,02788792 0,03439177 ! sister chromatid segregation GO:0000819 58 37 0,000 0,02788792 0,03437415 ! actomyosin structure organization GO:0031032 62 37 0,000 0,02788792 0,03435655 ! organic anion transport GO:0015711 68 37 0,000 0,02788792 0,03433897 ! tissue remodeling GO:0048771 76 37 0,000 0,02788792 0,0343214 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,02788792 0,03430386 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,02788792 0,03428633 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,02788792 0,03426882 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,02788792 0,03425132 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,02788792 0,03423385 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,02788792 0,03421639 ! glycogen metabolic process GO:0005977 61 37 0,000 0,02788792 0,03419895 ! pigment metabolic process GO:0042440 80 37 0,000 0,02788792 0,03418153 ! spermatid differentiation GO:0048515 66 37 0,000 0,02788792 0,03416413 ! cellular response to insulin stimulus GO:0032869 82 37 0,000 0,02788792 0,03414674 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,02863123 0,03503903 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,02863123 0,03502122 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,02863123 0,03500342 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,02863123 0,03498564 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,02863123 0,03496788 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,02863123 0,03495014 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,02863123 0,03493242 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,02863123 0,03491472 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,02863123 0,03489703 ! lipid homeostasis GO:0055088 67 38 0,000 0,02863123 0,03487936 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,02863123 0,03486171 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,02863123 0,03484407 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,02863123 0,03482646 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,02863123 0,03480886 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,02863123 0,03479128 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,02863123 0,03477372 ! glucan metabolic process GO:0044042 62 38 0,000 0,02863123 0,03475617 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,02937399 0,03563985 ! mammary gland development GO:0030879 86 39 0,000 0,02937399 0,03562188 ! learning GO:0007612 77 39 0,000 0,02937399 0,03560394 ! ear morphogenesis GO:0042471 60 39 0,000 0,02937399 0,03558601 ! organic ether metabolic process GO:0018904 55 39 0,000 0,02937399 0,0355681 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,02937399 0,03555021 ! segmentation GO:0035282 67 39 0,000 0,02937399 0,03553233 ! ion transmembrane transport GO:0034220 66 39 0,000 0,02937399 0,03551448 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,02937399 0,03549664 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,02937399 0,03547882 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,02937399 0,03546102 ! RNA modification GO:0009451 57 39 0,000 0,02937399 0,03544324 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,02937399 0,03542547 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,0301162 0,0363024 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,0301162 0,03628422 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,0301162 0,03626606 ! feeding behavior GO:0007631 59 40 0,000 0,0301162 0,03624792 ! negative regulation of binding GO:0051100 72 40 0,000 0,0301162 0,03622979 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,0301162 0,03621169 ! mesenchymal cell development GO:0014031 87 40 0,000 0,0301162 0,0361936 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,0301162 0,03617553 ! maintenance of protein location GO:0045185 91 40 0,000 0,0301162 0,03615748 ! cytokinesis GO:0000910 72 40 0,000 0,0301162 0,03613945 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,03085788 0,03701099 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,03085788 0,03699255 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,03085788 0,03697413 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,03085788 0,03695573 ! gliogenesis GO:0042063 88 41 0,000 0,03085788 0,03693734 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,03085788 0,03691897 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,03085788 0,03690062 ! T cell differentiation GO:0030217 81 41 0,000 0,03085788 0,03688229 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,03085788 0,03686398 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,03085788 0,03684568 ! female gamete generation GO:0007292 61 41 0,000 0,03085788 0,03682741 ! polyol metabolic process GO:0019751 66 41 0,000 0,03085788 0,03680915 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,03085788 0,03679091 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,03159901 0,03765588 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,03159901 0,03763724 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,03159901 0,03761861 ! regulation of tube size GO:0035150 71 42 0,000 0,03159901 0,03760001 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,03159901 0,03758142 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,03159901 0,03756285 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,03159901 0,0375443 ! regulation of intracellular protein transport GO:0033157 80 42 0,000 0,03159901 0,03752577 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,03159901 0,03750726 ! neuron migration GO:0001764 79 42 0,000 0,03159901 0,03748877 ! regulation of protein secretion GO:0050708 71 42 0,000 0,03159901 0,03747029 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,03159901 0,03745183 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,0323396 0,03831072 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,0323396 0,03829187 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,0323396 0,03827303 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,0323396 0,03825422 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,0323396 0,03823542 ! glucose transport GO:0015758 65 43 0,000 0,0323396 0,03821664 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,0323396 0,03819788 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,0323396 0,03817913 ! neural tube development GO:0021915 77 43 0,000 0,0323396 0,03816041 ! regulation of epithelial cell proliferation GO:0050678 111 43 0,000 0,0323396 0,0381417 ! striated muscle contraction GO:0006941 77 43 0,000 0,0323396 0,03812302 ! phagocytosis GO:0006909 90 43 0,000 0,0323396 0,03810435 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,0323396 0,0380857 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,03307965 0,03893817 ! hexose transport GO:0008645 67 44 0,000 0,03307965 0,03891913 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,03307965 0,03890011 ! male sex differentiation GO:0046661 76 44 0,000 0,03307965 0,03888111 ! double-strand break repair GO:0006302 81 44 0,000 0,03307965 0,03886212 ! biopolymer methylation GO:0043414 84 44 0,000 0,03307965 0,03884316 ! B cell differentiation GO:0030183 107 44 0,000 0,03307965 0,03882421 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,03307965 0,03880528 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,03307965 0,03878637 ! developmental growth GO:0048589 82 44 0,000 0,03307965 0,03876748 ! maintenance of location in cell GO:0051651 97 44 0,000 0,03307965 0,0387486 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,03381915 0,03959556 ! glycolysis GO:0006096 65 45 0,000 0,03381915 0,0395763 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,03381915 0,03955706 ! leukocyte migration GO:0050900 68 45 0,000 0,03381915 0,03953784 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,03381915 0,03951864 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,03381915 0,03949946 ! induction of apoptosis by intracellular signals GO:0008629 93 45 0,000 0,03381915 0,03948029 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,03381915 0,03946115 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,03381915 0,03944202 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,03381915 0,03942291 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,03381915 0,03940382 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,03381915 0,03938474 ! cell growth GO:0016049 84 45 0,000 0,03381915 0,03936569 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,03455812 0,0402064 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 0,000 0,03455812 0,04018697 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,03455812 0,04016755 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,03455812 0,04014816 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,03455812 0,04012878 ! pigmentation GO:0043473 100 46 0,000 0,03455812 0,04010942 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,03455812 0,04009008 ! positive regulation of defense response GO:0031349 76 47 0,000 0,03529654 0,04092698 ! endosome transport GO:0016197 108 47 0,000 0,03529654 0,04090726 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,03529654 0,04088757 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,03529654 0,04086789 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,03529654 0,04084823 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,03529654 0,0408286 ! JNK cascade GO:0007254 91 47 0,000 0,03529654 0,04080898 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,03529654 0,04078938 ! methylation GO:0032259 90 47 0,000 0,03529654 0,04076979 ! protein homooligomerization GO:0051260 76 47 0,000 0,03529654 0,04075023 ! mitochondrial transport GO:0006839 82 48 0,000 0,03603443 0,04158217 ! Notch signaling pathway GO:0007219 96 48 0,000 0,03603443 0,04156224 ! cellular component disassembly GO:0022411 86 48 0,000 0,03603443 0,04154232 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,03603443 0,04152243 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,03603443 0,04150255 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,03603443 0,04148269 ! activation of caspase activity GO:0006919 84 48 0,000 0,03603443 0,04146286 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,03603443 0,04144304 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,03603443 0,04142323 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,03603443 0,04140345 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,03603443 0,04138369 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,03677177 0,04221034 ! regulation of action potential GO:0001508 95 49 0,000 0,03677177 0,04219021 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,03677177 0,04217011 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,03677177 0,04215001 ! regulation of ion transport GO:0043269 77 49 0,000 0,03677177 0,04212994 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,03677177 0,04210989 ! peptide metabolic process GO:0006518 76 49 0,000 0,03677177 0,04208986 ! response to temperature stimulus GO:0009266 76 49 0,000 0,03677177 0,04206984 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,03677177 0,04204985 ! endocrine system development GO:0035270 104 49 0,000 0,03677177 0,04202987 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,03677177 0,04200991 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,03677177 0,04198998 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,03677177 0,04197006 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,03677177 0,04195016 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,03750858 0,04277044 ! neuromuscular process GO:0050905 99 50 0,000 0,03750858 0,04275018 ! regulation of ossification GO:0030278 117 50 0,000 0,03750858 0,04272994 ! inner ear development GO:0048839 79 50 0,000 0,03750858 0,04270972 ! histone modification GO:0016570 91 50 0,000 0,03750858 0,04268951 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,03750858 0,04266933 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,03750858 0,04264917 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,03750858 0,04262902 ! positive regulation of binding GO:0051099 78 51 0,000 0,03824484 0,04344527 ! viral infectious cycle GO:0019058 99 51 0,000 0,03824484 0,04342477 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,03824484 0,04340429 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,03824484 0,04338382 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,03824484 0,04336338 ! excretion GO:0007588 83 51 0,000 0,03824484 0,04334295 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,03824484 0,04332255 ! chromatin remodeling GO:0006338 109 51 0,000 0,03824484 0,04330216 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,03824484 0,04328179 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,03824484 0,04326144 ! vesicle organization GO:0016050 107 51 0,000 0,03824484 0,04324111 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,03824484 0,0432208 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 0,000 0,03824484 0,04320051 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,03824484 0,04318024 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,03898057 0,04399027 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,03898057 0,04396964 ! membrane fusion GO:0006944 110 52 0,000 0,03898057 0,04394904 ! positive regulation of growth GO:0045927 90 52 0,000 0,03898057 0,04392845 ! covalent chromatin modification GO:0016569 101 52 0,000 0,03898057 0,04390789 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,03898057 0,04388734 ! amino acid activation GO:0043038 92 52 0,000 0,03898057 0,04386681 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,03898057 0,04384631 ! synapse organization GO:0050808 85 52 0,000 0,03898057 0,04382582 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,03971576 0,04463153 ! RNA catabolic process GO:0006401 93 53 0,000 0,03971576 0,0446107 ! regulation of translational initiation GO:0006446 82 53 0,000 0,03971576 0,04458988 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,03971576 0,04456908 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,03971576 0,0445483 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,03971576 0,04452755 ! cell maturation GO:0048469 100 53 0,000 0,03971576 0,04450681 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,03971576 0,04448609 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,03971576 0,04446538 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,04045041 0,04526683 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,04045041 0,04524578 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,04045041 0,04522476 ! cell recognition GO:0008037 85 54 0,000 0,04045041 0,04520375 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,04045041 0,04518277 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,04045041 0,0451618 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,04045041 0,04514085 ! chloride transport GO:0006821 90 55 0,000 0,04118452 0,04593878 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,04118452 0,0459175 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,04118452 0,04589623 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,04118452 0,04587498 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,04118452 0,04585375 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,04118452 0,04583254 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,04118452 0,04581135 ! aging GO:0007568 103 55 0,000 0,04118452 0,04579018 ! gastrulation GO:0007369 112 55 0,000 0,04118452 0,04576903 ! heart morphogenesis GO:0003007 97 55 0,000 0,04118452 0,0457479 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,04118452 0,04572679 ! RNA elongation GO:0006354 79 55 0,000 0,04118452 0,0457057 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,04118452 0,04568463 ! regulation of actin filament length GO:0030832 105 56 0,000 0,0419181 0,04647693 ! sensory perception of smell GO:0007608 80 56 0,000 0,0419181 0,04645552 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,0419181 0,04643413 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,0419181 0,04641277 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,0419181 0,04639142 ! regulation of DNA replication GO:0006275 101 56 0,000 0,0419181 0,04637009 ! proton transport GO:0015992 94 56 0,000 0,0419181 0,04634878 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,0419181 0,04632749 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,04265114 0,04711599 ! muscle fiber development GO:0048747 112 57 0,000 0,04265114 0,04709437 ! positive regulation of cell migration GO:0030335 126 57 0,000 0,04265114 0,04707277 ! lipid modification GO:0030258 97 57 0,000 0,04265114 0,04705118 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,04265114 0,04702962 ! regulation of intracellular transport GO:0032386 101 57 0,000 0,04265114 0,04700808 ! maintenance of location GO:0051235 118 57 0,000 0,04265114 0,04698655 ! hydrogen transport GO:0006818 97 58 0,000 0,04338364 0,04777164 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,04338364 0,04774979 ! regulation of endocytosis GO:0030100 91 58 0,000 0,04338364 0,04772795 ! adult behavior GO:0030534 99 58 0,000 0,04338364 0,04770614 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,04338364 0,04768435 ! positive regulation of secretion GO:0051047 95 59 0,000 0,0441156 0,04846673 ! regulation of cellular component size GO:0032535 109 59 0,000 0,0441156 0,04844461 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,0441156 0,04842251 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,0441156 0,04840043 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,0441156 0,04837837 ! DNA catabolic process GO:0006308 86 59 0,000 0,0441156 0,04835633 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,0441156 0,04833431 ! establishment of organelle localization GO:0051656 109 59 0,000 0,0441156 0,04831231 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,04484704 0,04909098 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,04484704 0,04906865 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,04484704 0,04904635 ! regulation of heart contraction GO:0008016 110 60 0,000 0,04484704 0,04902406 ! camera-type eye development GO:0043010 116 60 0,000 0,04484704 0,0490018 ! protein amino acid autophosphorylation GO:0046777 141 60 0,000 0,04484704 0,04897956 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,04484704 0,04895733 ! kidney development GO:0001822 122 60 0,000 0,04484704 0,04893513 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,04557793 0,04971011 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,04557793 0,04968759 ! mesoderm development GO:0007498 119 61 0,000 0,04557793 0,04966508 ! tRNA processing GO:0008033 89 61 0,000 0,04557793 0,0496426 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,04557793 0,04962014 ! ear development GO:0043583 103 62 0,000 0,04630829 0,05039247 ! viral reproductive process GO:0022415 126 62 0,000 0,04630829 0,05036969 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,04630829 0,05034693 ! gonad development GO:0008406 98 62 0,000 0,04630829 0,05032419 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,04630829 0,05030147 ! regulation of mitosis GO:0007088 105 63 0,000 0,04703812 0,05107117 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,04703812 0,05104813 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,04703812 0,05102512 ! detection of external stimulus GO:0009581 91 63 0,000 0,04703812 0,05100212 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,04703812 0,05097915 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,04703812 0,05095619 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,04776741 0,05172294 ! cell redox homeostasis GO:0045454 102 64 0,000 0,04776741 0,05169968 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,04776741 0,05167643 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,04776741 0,05165321 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,04776741 0,05163 ! positive regulation of cell motion GO:0051272 146 64 0,000 0,04776741 0,05160682 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,04849617 0,05237063 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,04849617 0,05234714 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,04849617 0,05232367 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,04849617 0,05230021 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,04849617 0,05227678 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,04922439 0,05303801 ! actin filament organization GO:0007015 148 66 0,000 0,04922439 0,05301427 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,04922439 0,05299055 ! extracellular matrix organization GO:0030198 133 66 0,000 0,04922439 0,05296685 ! secondary metabolic process GO:0019748 116 66 0,000 0,04922439 0,05294317 ! developmental maturation GO:0021700 116 66 0,000 0,04922439 0,05291952 ! cell projection assembly GO:0030031 120 66 0,000 0,04922439 0,05289588 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,04995208 0,05365389 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,04995208 0,05362994 ! negative regulation of protein kinase activity GO:0006469 130 67 0,000 0,04995208 0,05360602 ! negative regulation of cell growth GO:0030308 132 67 0,000 0,04995208 0,05358212 ! activation of MAPK activity GO:0000187 115 67 0,000 0,04995208 0,05355825 ! lung development GO:0030324 144 67 0,000 0,04995208 0,05353439 ! chromosome segregation GO:0007059 113 67 0,000 0,04995208 0,05351055 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,04995208 0,05348674 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,04995208 0,05346295 ! hexose catabolic process GO:0019320 104 67 0,000 0,04995208 0,05343917 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,04995208 0,05341542 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,04995208 0,05339169 ! adaptive immune response GO:0002250 119 67 0,000 0,04995208 0,05336799 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,04995208 0,0533443 ! amino acid transport GO:0006865 125 68 0,000 0,05067924 0,05409683 ! negative regulation of kinase activity GO:0033673 131 68 0,000 0,05067924 0,05407284 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,05067924 0,05404887 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,05067924 0,05402492 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,05067924 0,054001 ! viral reproduction GO:0016032 134 68 0,000 0,05067924 0,05397709 ! regulation of lipase activity GO:0060191 130 68 0,000 0,05067924 0,05395321 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,05067924 0,05392934 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,05140586 0,05467839 ! negative regulation of cell size GO:0045792 134 69 0,000 0,05140586 0,05465422 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,05140586 0,05463008 ! urogenital system development GO:0001655 137 69 0,000 0,05140586 0,05460596 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,05140586 0,05458187 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,05140586 0,05455779 ! antigen processing and presentation GO:0019882 104 69 0,000 0,05140586 0,05453373 ! appendage morphogenesis GO:0035107 135 70 0,000 0,05213196 0,05527963 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 0,000 0,05213196 0,05525528 ! amine catabolic process GO:0009310 117 71 0,000 0,05285752 0,05599964 ! reproductive structure development GO:0048608 113 71 0,000 0,05285752 0,055975 ! appendage development GO:0048736 136 71 0,000 0,05285752 0,05595037 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,05285752 0,05592577 ! B cell activation GO:0042113 160 71 0,000 0,05285752 0,05590118 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,05285752 0,05587662 ! regulation of immune effector process GO:0002697 137 71 0,000 0,05285752 0,05585208 ! acute inflammatory response GO:0002526 113 72 0,000 0,05358255 0,05659333 ! regulation of caspase activity GO:0043281 122 72 0,000 0,05358255 0,0565685 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,05358255 0,05654369 ! carbohydrate transport GO:0008643 110 72 0,000 0,05358255 0,0565189 ! negative regulation of transferase activity GO:0051348 140 72 0,000 0,05358255 0,05649414 ! respiratory system development GO:0060541 153 72 0,000 0,05358255 0,05646939 ! learning or memory GO:0007611 147 73 0,000 0,05430705 0,05720786 ! regulation of blood pressure GO:0008217 125 73 0,000 0,05430705 0,05718283 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,05430705 0,05715781 ! axon guidance GO:0007411 139 73 0,000 0,05430705 0,05713282 ! fertilization GO:0009566 90 73 0,000 0,05430705 0,05710785 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,05503102 0,05784388 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,05503102 0,05781862 ! neurotransmitter transport GO:0006836 123 74 0,000 0,05503102 0,05779338 ! meiosis GO:0007126 121 74 0,000 0,05503102 0,05776816 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,05503102 0,05774297 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,05503102 0,0577178 ! regulation of endopeptidase activity GO:0052548 125 74 0,000 0,05503102 0,05769265 ! eye development GO:0001654 143 74 0,000 0,05503102 0,05766752 ! organelle localization GO:0051640 136 74 0,000 0,05503102 0,05764242 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,05575446 0,05837477 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,05575446 0,05834938 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,05575446 0,05832401 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,05575446 0,05829867 ! meiotic cell cycle GO:0051321 122 75 0,000 0,05575446 0,05827334 ! rhythmic process GO:0048511 128 75 0,000 0,05575446 0,05824804 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,05575446 0,05822276 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,05647737 0,05895208 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,05647737 0,05892652 ! defense response to bacterium GO:0042742 89 76 0,000 0,05647737 0,05890097 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,05647737 0,05887545 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,05647737 0,05884996 ! regulation of catabolic process GO:0009894 161 76 0,000 0,05647737 0,05882448 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,05719975 0,0595511 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,05719975 0,05952534 ! blood coagulation GO:0007596 146 78 0,000 0,0579216 0,06025048 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,0579216 0,06022445 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,0579216 0,06019843 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,0579216 0,06017244 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,05864292 0,0608955 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,05864292 0,06086923 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,05864292 0,06084298 ! regulation of peptidase activity GO:0052547 134 79 0,000 0,05864292 0,06081675 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,05864292 0,06079055 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,05936372 0,06151124 ! muscle cell differentiation GO:0042692 159 80 0,000 0,05936372 0,06148476 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,05936372 0,06145831 ! protein import into nucleus GO:0006606 158 80 0,000 0,05936372 0,06143187 ! inorganic anion transport GO:0015698 138 80 0,000 0,05936372 0,06140546 ! T cell activation GO:0042110 168 81 0,000 0,06008398 0,06212379 ! response to hypoxia GO:0001666 171 81 0,000 0,06008398 0,06209711 ! digestion GO:0007586 112 81 0,000 0,06008398 0,06207044 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,06008398 0,0620438 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,06008398 0,06201719 ! nuclear import GO:0051170 161 81 0,000 0,06008398 0,06199059 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,06008398 0,06196402 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,06080372 0,06267941 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,06080372 0,06265257 ! response to drug GO:0042493 143 82 0,000 0,06080372 0,06262575 ! response to nutrient GO:0007584 125 82 0,000 0,06080372 0,06259895 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,06080372 0,06257218 ! cellular response to hormone stimulus GO:0032870 167 82 0,000 0,06080372 0,06254543 ! response to oxygen levels GO:0070482 176 83 0,000 0,06152293 0,06325819 ! regulation of lyase activity GO:0051339 160 83 0,000 0,06152293 0,06323117 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,06224162 0,0639425 ! hemostasis GO:0007599 158 84 0,000 0,06224162 0,06391521 ! negative regulation of transport GO:0051051 153 84 0,000 0,06224162 0,06388794 ! negative regulation of growth GO:0045926 155 84 0,000 0,06224162 0,0638607 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,06224162 0,06383347 ! nucleosome assembly GO:0006334 122 85 0,000 0,06295978 0,06454249 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,06295978 0,064515 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,06295978 0,06448753 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,06367741 0,06519483 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,06367741 0,0651671 ! chromatin assembly GO:0031497 124 86 0,000 0,06367741 0,06513939 ! tube morphogenesis GO:0035239 176 86 0,000 0,06367741 0,06511171 ! mitochondrion organization GO:0007005 148 86 0,000 0,06367741 0,06508405 ! alcohol catabolic process GO:0046164 130 86 0,000 0,06367741 0,06505641 ! amine transport GO:0015837 155 86 0,000 0,06367741 0,0650288 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,06439451 0,06573322 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,06439451 0,06570534 ! protein localization in nucleus GO:0034504 176 87 0,000 0,06439451 0,06567749 ! regulation of protein transport GO:0051223 154 87 0,000 0,06439451 0,06564966 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 135 88 0,000 0,06511109 0,06635209 ! regulation of DNA binding GO:0051101 155 88 0,000 0,06511109 0,066324 ! gland development GO:0048732 206 88 0,000 0,06511109 0,06629593 ! regulation of neurological system process GO:0031644 148 88 0,000 0,06511109 0,06626789 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,06511109 0,06623987 ! cellular defense response GO:0006968 114 89 0,000 0,06582715 0,06694004 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,06582715 0,06691176 ! ossification GO:0001503 188 90 0,000 0,06654268 0,06761051 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,06654268 0,06758197 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,06654268 0,06755346 ! sex differentiation GO:0007548 145 90 0,000 0,06654268 0,06752497 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,06654268 0,0674965 ! bone development GO:0060348 189 91 0,000 0,06725769 0,068193 ! sterol metabolic process GO:0016125 152 91 0,000 0,06725769 0,06816428 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,06725769 0,06813558 ! regulation of defense response GO:0031347 149 92 0,000 0,06797217 0,06883041 ! nucleosome organization GO:0034728 138 92 0,000 0,06797217 0,06880145 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,06797217 0,06877252 ! vitamin metabolic process GO:0006766 139 92 0,000 0,06797217 0,06874361 ! positive regulation of MAP kinase activity GO:0043406 160 93 0,000 0,06868613 0,06943648 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,06868613 0,06940732 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,06868613 0,06937818 ! regulation of membrane potential GO:0042391 164 93 0,000 0,06868613 0,06934907 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,06868613 0,06931998 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,06939957 0,07001063 ! female pregnancy GO:0007565 164 94 0,000 0,06939957 0,06998129 ! transcription initiation GO:0006352 153 94 0,000 0,06939957 0,06995197 ! regulation of T cell activation GO:0050863 158 94 0,000 0,06939957 0,06992268 ! forebrain development GO:0030900 188 95 0,000 0,07011248 0,0706114 ! leukocyte differentiation GO:0002521 202 96 0,000 0,07082487 0,07129901 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,07082487 0,0712692 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,07082487 0,0712394 ! positive regulation of immune response GO:0050778 156 96 0,000 0,07082487 0,07120963 ! detection of stimulus GO:0051606 151 96 0,000 0,07082487 0,07117989 ! regulation of DNA metabolic process GO:0051052 178 97 0,000 0,07153674 0,0718653 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,07153674 0,07183531 ! protein ubiquitination GO:0016567 217 97 0,000 0,07153674 0,07180534 ! hormone metabolic process GO:0042445 157 97 0,000 0,07153674 0,0717754 ! regulation of protein localization GO:0032880 176 97 0,000 0,07153674 0,07174548 ! response to virus GO:0009615 160 98 0,000 0,07224809 0,07242871 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,07224809 0,07239854 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,07224809 0,0723684 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,07295892 0,07305 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,07295892 0,07301961 ! skeletal muscle tissue development GO:0007519 186 99 0,000 0,07295892 0,07298925 GO:0060538|skeletal muscle organ development, ! cell cycle arrest GO:0007050 213 100 0,000 0,07366922 0,07366922