pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-b1/out-0.05-06-0.01-300-run-b1//th1-pval-1e-01-08-th2-pval-1e-02-02-th3-pval-1e-01-01-run-b1/go_data/59341-7-real-Pawitan_GPL96-GPL97-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 7,395E-06 0,01779296 ! cell volume homeostasis GO:0006884 17 10 1,000 1,188E-05 0,01428905 ! response to osmotic stress GO:0006970 25 16 1,000 3,162E-05 0,02535557 ! cellular response to unfolded protein GO:0034620 33 19 1,000 4,501E-05 0,02707358 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 7,882E-05 0,03792743 ! fat cell differentiation GO:0045444 50 27 1,000 9,216E-05 0,03695633 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 9,922E-05 0,03410297 ! response to mechanical stimulus GO:0009612 57 32 1,000 1,3E-04 0,03910676 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 1,000 2,702E-04 0,07222279 ! response to calcium ion GO:0051592 81 47 1,000 2,821E-04 0,06786839 ! positive regulation of cell cycle GO:0045787 89 48 1,000 2,943E-04 0,06436114 ! response to UV GO:0009411 104 53 1,000 3,589E-04 0,07196191 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 1,000 4,152E-04 0,07683979 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 5,906E-04 0,10149456 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 6,08E-04 0,09752575 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 1,000 6,618E-04 0,0995222 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 6,618E-04 0,09366795 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 1,000 6,618E-04 0,08846418 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 1,000 7,179E-04 0,09090443 ! cytosolic calcium ion homeostasis GO:0051480 135 76 1,000 7,37E-04 0,08866578 ! positive regulation of ligase activity GO:0051351 124 77 1,000 7,565E-04 0,08666859 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 1,000 7,96E-04 0,08705761 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 7,96E-04 0,0832725 ! response to metal ion GO:0010038 140 80 1,000 8,162E-04 0,0818237 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 8,366E-04 0,08051444 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of ligase activity GO:0051340 142 84 1,000 8,993E-04 0,08321841 ! response to unfolded protein GO:0006986 131 85 1,000 9,207E-04 0,08204184 ! response to inorganic substance GO:0010035 153 86 1,000 9,423E-04 0,08097031 ! positive regulation of protein modification process GO:0031401 136 88 1,000 9,863E-04 0,08182791 ! response to protein stimulus GO:0051789 149 91 1,000 1,054E-03 0,08453895 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 1,101E-03 0,08541505 GO:0010498|proteasomal protein catabolic process, ! interphase of mitotic cell cycle GO:0051329 209 95 1,000 1,148E-03 0,08630936 ! interphase GO:0051325 213 98 1,000 1,221E-03 0,08900962 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 2,654E-03 0,18778563 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 2,654E-03 0,18242032 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 2,654E-03 0,17735309 ! positive regulation of helicase activity GO:0051096 11 5 0,000 2,654E-03 0,17255977 ! neuron fate determination GO:0048664 7 5 0,000 2,654E-03 0,16801872 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 2,654E-03 0,16371055 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 2,654E-03 0,15961778 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 2,654E-03 0,15572467 ! polyol transport GO:0015791 12 5 0,000 2,654E-03 0,15201694 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 2,654E-03 0,14848166 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 2,654E-03 0,14510708 ! response to superoxide GO:0000303 10 5 0,000 2,654E-03 0,14188247 ! negative regulation of bone resorption GO:0045779 10 5 0,000 2,654E-03 0,13879807 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 2,654E-03 0,13584492 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 2,654E-03 0,13301482 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 2,654E-03 0,13030023 ! female meiosis GO:0007143 7 5 0,000 2,654E-03 0,12769423 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 2,654E-03 0,12519042 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 2,654E-03 0,12278291 ! cobalt ion transport GO:0006824 11 5 0,000 2,654E-03 0,12046625 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 2,654E-03 0,11823539 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 2,654E-03 0,11608566 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 2,654E-03 0,1140127 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 2,654E-03 0,11201248 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 2,654E-03 0,11008123 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 2,654E-03 0,10821545 ! embryonic camera-type eye development GO:0031076 10 5 0,000 2,654E-03 0,10641186 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 2,654E-03 0,1046674 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 2,654E-03 0,10297921 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 2,654E-03 0,10134462 ! adaptation of signaling pathway GO:0022401 7 5 0,000 2,654E-03 0,09976111 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 2,654E-03 0,09822633 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 2,654E-03 0,09673805 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 2,654E-03 0,0952942 ! negative chemotaxis GO:0050919 14 5 0,000 2,654E-03 0,09389281 ! positive regulation of histone modification GO:0031058 5 5 0,000 2,654E-03 0,09253205 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 2,654E-03 0,09121016 ! sensory perception of bitter taste GO:0050913 7 5 0,000 2,654E-03 0,08992551 ! behavioral response to pain GO:0048266 9 5 0,000 2,654E-03 0,08867655 ! clathrin coat assembly GO:0048268 14 5 0,000 2,654E-03 0,0874618 ! Notch receptor processing GO:0007220 8 5 0,000 2,654E-03 0,08627988 ! regulation of dopamine uptake GO:0051584 9 5 0,000 2,654E-03 0,08512948 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 2,654E-03 0,08400936 ! micturition GO:0060073 9 5 0,000 2,654E-03 0,08291833 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 2,654E-03 0,08185527 ! copulation GO:0007620 9 5 0,000 2,654E-03 0,08081913 ! glial cell fate commitment GO:0021781 13 5 0,000 2,654E-03 0,07980889 ! protein maturation by protein folding GO:0022417 13 5 0,000 2,654E-03 0,0788236 ! spermidine metabolic process GO:0008216 7 5 0,000 2,654E-03 0,07786233 ! regulation of potassium ion transport GO:0043266 10 5 0,000 2,654E-03 0,07692423 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 2,654E-03 0,07600847 ! apoptotic cell clearance GO:0043277 20 5 0,000 2,654E-03 0,07511425 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 2,654E-03 0,07424083 ! lipoprotein particle clearance GO:0034381 10 5 0,000 2,654E-03 0,07338749 ! grooming behavior GO:0007625 6 5 0,000 2,654E-03 0,07255354 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 2,654E-03 0,07173833 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 2,654E-03 0,07094124 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 2,654E-03 0,07016166 ! response to protozoan GO:0001562 10 5 0,000 2,654E-03 0,06939904 ! positive regulation of glycolysis GO:0045821 14 5 0,000 2,654E-03 0,06865281 ! lymph vessel development GO:0001945 10 5 0,000 2,654E-03 0,06792246 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 2,654E-03 0,06720749 ! endochondral ossification GO:0001958 16 5 0,000 2,654E-03 0,06650741 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 2,654E-03 0,06582177 ! parathyroid gland development GO:0060017 13 5 0,000 2,654E-03 0,06515012 ! anagen GO:0042640 6 5 0,000 2,654E-03 0,06449203 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 2,654E-03 0,06384711 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 2,654E-03 0,06321496 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 2,654E-03 0,06259521 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 2,654E-03 0,06198749 ! dorsal spinal cord development GO:0021516 7 5 0,000 2,654E-03 0,06139145 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 2,654E-03 0,06080677 ! sphingoid catabolic process GO:0046521 6 5 0,000 2,654E-03 0,06023313 ! skeletal myofibril assembly GO:0014866 10 5 0,000 2,654E-03 0,0596702 ! smooth muscle tissue development GO:0048745 28 5 0,000 2,654E-03 0,0591177 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 2,654E-03 0,05857533 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 2,654E-03 0,05804283 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 2,654E-03 0,05751992 ! cardiac muscle fiber development GO:0048739 10 5 0,000 2,654E-03 0,05700635 ! transepithelial chloride transport GO:0030321 9 5 0,000 2,654E-03 0,05650187 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 2,654E-03 0,05600624 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 2,654E-03 0,05551923 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 2,654E-03 0,05504061 ! neutrophil mediated immunity GO:0002446 7 5 0,000 2,654E-03 0,05457018 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 2,654E-03 0,05410772 ! histidine catabolic process GO:0006548 6 5 0,000 2,654E-03 0,05365304 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 2,654E-03 0,05320593 ! microvillus organization GO:0032528 7 5 0,000 2,654E-03 0,05276621 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 2,654E-03 0,0523337 ! L-serine biosynthetic process GO:0006564 6 5 0,000 2,654E-03 0,05190822 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 2,654E-03 0,05148961 ! tryptophan metabolic process GO:0006568 9 5 0,000 2,654E-03 0,05107769 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 2,654E-03 0,05067231 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 2,654E-03 0,05027332 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 2,654E-03 0,04988056 ! polyol catabolic process GO:0046174 7 5 0,000 2,654E-03 0,04949389 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 2,654E-03 0,04911316 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 2,654E-03 0,04873825 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 2,654E-03 0,04836903 ! muscle cell migration GO:0014812 8 5 0,000 2,654E-03 0,04800535 ! mitochondrial fission GO:0000266 8 5 0,000 2,654E-03 0,0476471 ! sister chromatid cohesion GO:0007062 12 5 0,000 2,654E-03 0,04729416 ! mRNA transcription GO:0009299 9 5 0,000 2,654E-03 0,04694641 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 2,654E-03 0,04660373 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 2,654E-03 0,04626602 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 2,654E-03 0,04593317 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 2,654E-03 0,04560508 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 2,654E-03 0,04528164 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 2,654E-03 0,04496276 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 2,654E-03 0,04464833 ! response to food GO:0032094 6 5 0,000 2,654E-03 0,04433827 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 2,654E-03 0,04403249 ! positive regulation of transporter activity GO:0032411 8 5 0,000 2,654E-03 0,0437309 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 2,654E-03 0,04343341 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 2,654E-03 0,04313994 ! paraxial mesoderm development GO:0048339 14 5 0,000 2,654E-03 0,04285041 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 2,654E-03 0,04256474 ! forebrain neuron development GO:0021884 13 5 0,000 2,654E-03 0,04228286 ! lipoprotein catabolic process GO:0042159 11 5 0,000 2,654E-03 0,04200468 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 2,654E-03 0,04173014 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 2,654E-03 0,04145916 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 2,654E-03 0,04119169 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 2,654E-03 0,04092764 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 2,654E-03 0,04066695 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 2,654E-03 0,04040957 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 2,654E-03 0,04015542 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 2,654E-03 0,03990445 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 2,654E-03 0,03965659 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 2,654E-03 0,0394118 ! basic amino acid transport GO:0015802 11 5 0,000 2,654E-03 0,03917001 ! cellular glucose homeostasis GO:0001678 5 5 0,000 2,654E-03 0,03893117 ! early endosome to late endosome transport GO:0045022 12 5 0,000 2,654E-03 0,03869522 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 2,654E-03 0,03846212 ! depyrimidination GO:0045008 10 5 0,000 2,654E-03 0,0382318 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 2,654E-03 0,03800423 ! regulation of centrosome cycle GO:0046605 7 5 0,000 2,654E-03 0,03777936 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 2,654E-03 0,03755713 ! zinc ion homeostasis GO:0055069 8 5 0,000 2,654E-03 0,03733749 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 2,654E-03 0,03712041 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 2,654E-03 0,03690585 ! forebrain morphogenesis GO:0048853 13 5 0,000 2,654E-03 0,03669374 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 2,654E-03 0,03648406 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 2,654E-03 0,03627677 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 2,654E-03 0,03607182 ! peptidyl-arginine modification GO:0018195 9 5 0,000 2,654E-03 0,03586916 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 2,654E-03 0,03566878 ! positive regulation of organ growth GO:0046622 6 5 0,000 2,654E-03 0,03547062 ! response to arsenic GO:0046685 10 5 0,000 2,654E-03 0,03527465 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 2,654E-03 0,03508083 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 2,654E-03 0,03488913 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 2,654E-03 0,03469952 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 2,654E-03 0,03451195 ! response to cadmium ion GO:0046686 7 5 0,000 2,654E-03 0,0343264 ! bile acid biosynthetic process GO:0006699 6 5 0,000 2,654E-03 0,03414284 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 2,654E-03 0,03396123 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 2,654E-03 0,03378154 ! decidualization GO:0046697 11 5 0,000 2,654E-03 0,03360374 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 2,654E-03 0,03342781 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 2,654E-03 0,0332537 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 2,654E-03 0,03308141 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 2,654E-03 0,03291088 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 2,654E-03 0,03274211 ! base conversion or substitution editing GO:0016553 5 5 0,000 2,654E-03 0,03257506 ! neural tube patterning GO:0021532 7 5 0,000 2,654E-03 0,0324097 ! embryonic cleavage GO:0040016 6 5 0,000 2,654E-03 0,03224602 ! peroxisome fission GO:0016559 5 5 0,000 2,654E-03 0,03208398 ! histone demethylation GO:0016577 10 5 0,000 2,654E-03 0,03192356 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 2,654E-03 0,03176473 ! mitotic recombination GO:0006312 9 5 0,000 2,654E-03 0,03160748 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 2,654E-03 0,03145178 ! metaphase plate congression GO:0051310 7 5 0,000 2,654E-03 0,0312976 ! regulation of sterol transport GO:0032371 7 5 0,000 2,654E-03 0,03114493 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 2,654E-03 0,03099374 ! enteric nervous system development GO:0048484 8 5 0,000 2,654E-03 0,03084402 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 2,654E-03 0,03069573 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 2,654E-03 0,03054886 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 2,654E-03 0,03040339 ! muscle cell proliferation GO:0033002 11 5 0,000 2,654E-03 0,0302593 ! skeletal muscle regeneration GO:0043403 8 5 0,000 2,654E-03 0,03011656 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 2,654E-03 0,02997517 ! plasminogen activation GO:0031639 5 5 0,000 2,654E-03 0,0298351 ! B cell homeostasis GO:0001782 13 5 0,000 2,654E-03 0,02969633 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 2,654E-03 0,02955885 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 2,654E-03 0,02942263 ! metaphase GO:0051323 8 5 0,000 2,654E-03 0,02928767 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 2,654E-03 0,02915393 ! cellular response to nutrient GO:0031670 8 5 0,000 2,654E-03 0,02902142 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 2,654E-03 0,0288901 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 2,654E-03 0,02875996 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 2,654E-03 0,02863099 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 2,654E-03 0,02850318 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 2,654E-03 0,02837649 ! response to redox state GO:0051775 5 5 0,000 2,654E-03 0,02825093 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 2,654E-03 0,02812648 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 2,654E-03 0,02800312 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 2,654E-03 0,02788084 ! regulation of telomerase activity GO:0051972 6 5 0,000 2,654E-03 0,02775961 ! galactolipid metabolic process GO:0019374 7 5 0,000 2,654E-03 0,02763944 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 2,654E-03 0,02752031 ! porphyrin catabolic process GO:0006787 12 5 0,000 2,654E-03 0,02740219 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 2,654E-03 0,02728509 ! striatum development GO:0021756 9 5 0,000 2,654E-03 0,02716898 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 2,654E-03 0,02705386 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 2,654E-03 0,02693971 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 2,654E-03 0,02682652 ! glial cell migration GO:0008347 11 5 0,000 2,654E-03 0,02671427 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 2,654E-03 0,02660296 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 2,654E-03 0,02649258 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 2,654E-03 0,0263831 ! somatic stem cell maintenance GO:0035019 15 5 0,000 2,654E-03 0,02627453 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 2,654E-03 0,02616685 ! negative regulation of lipase activity GO:0060192 8 5 0,000 2,654E-03 0,02606005 ! neuroprotection GO:0043526 6 5 0,000 2,654E-03 0,02595411 ! neural plate development GO:0001840 8 5 0,000 2,654E-03 0,02584903 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 2,654E-03 0,0257448 ! regulation of sensory perception GO:0051931 7 5 0,000 2,654E-03 0,02564141 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 2,654E-03 0,02553885 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 2,654E-03 0,0254371 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 2,654E-03 0,02533616 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 2,654E-03 0,02523601 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 2,654E-03 0,02513666 ! sequestering of calcium ion GO:0051208 7 5 0,000 2,654E-03 0,02503808 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 2,654E-03 0,02494028 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 2,654E-03 0,02484323 ! spindle assembly GO:0051225 6 5 0,000 2,654E-03 0,02474694 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 2,654E-03 0,0246514 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 2,654E-03 0,02455658 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 2,654E-03 0,0244625 ! drug metabolic process GO:0017144 6 5 0,000 2,654E-03 0,02436913 ! stem cell division GO:0017145 11 5 0,000 2,654E-03 0,02427647 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 2,654E-03 0,02418451 ! organ regeneration GO:0031100 7 5 0,000 2,654E-03 0,02409325 ! carnitine metabolic process GO:0009437 7 5 0,000 2,654E-03 0,02400267 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 2,654E-03 0,02391278 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 2,654E-03 0,02382355 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 3,184E-03 0,02847489 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 3,184E-03 0,02836943 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 3,184E-03 0,02826475 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 3,184E-03 0,02816083 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 3,184E-03 0,02805768 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 3,184E-03 0,02795528 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 3,184E-03 0,02785362 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 3,184E-03 0,0277527 ! sleep GO:0030431 13 6 0,000 3,184E-03 0,02765251 ! response to oxygen radical GO:0000305 11 6 0,000 3,184E-03 0,02755304 ! positive regulation of axon extension GO:0045773 11 6 0,000 3,184E-03 0,02745429 ! myoblast cell fate commitment GO:0048625 16 6 0,000 3,184E-03 0,02735624 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 3,184E-03 0,02725888 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 3,184E-03 0,02716222 ! regulation of interferon-beta production GO:0032648 8 6 0,000 3,184E-03 0,02706624 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 3,184E-03 0,02697094 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 3,184E-03 0,0268763 ! forebrain regionalization GO:0021871 8 6 0,000 3,184E-03 0,02678233 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 3,184E-03 0,02668901 ! male meiosis GO:0007140 7 6 0,000 3,184E-03 0,02659634 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 3,184E-03 0,02650431 ! response to zinc ion GO:0010043 9 6 0,000 3,184E-03 0,02641292 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 3,184E-03 0,02632215 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 3,184E-03 0,02623201 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 3,184E-03 0,02614248 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 3,184E-03 0,02605356 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 3,184E-03 0,02596524 ! malate metabolic process GO:0006108 11 6 0,000 3,184E-03 0,02587752 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 3,184E-03 0,02579039 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 3,184E-03 0,02570385 ! protein refolding GO:0042026 15 6 0,000 3,184E-03 0,02561788 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 3,184E-03 0,02553249 ! opsonization GO:0008228 8 6 0,000 3,184E-03 0,02544766 ! mating behavior GO:0007617 7 6 0,000 3,184E-03 0,0253634 ! neuron remodeling GO:0016322 15 6 0,000 3,184E-03 0,02527969 ! erythrocyte maturation GO:0043249 7 6 0,000 3,184E-03 0,02519653 ! embryonic hemopoiesis GO:0035162 14 6 0,000 3,184E-03 0,02511392 ! equilibrioception GO:0050957 14 6 0,000 3,184E-03 0,02503185 ! protein amino acid dealkylation GO:0008214 12 6 0,000 3,184E-03 0,02495031 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 3,184E-03 0,02486931 ! photoreceptor cell development GO:0042461 10 6 0,000 3,184E-03 0,02478882 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 3,184E-03 0,02470886 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 3,184E-03 0,02462941 ! response to interferon-gamma GO:0034341 15 6 0,000 3,184E-03 0,02455047 ! toxin metabolic process GO:0009404 11 6 0,000 3,184E-03 0,02447203 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 3,184E-03 0,0243941 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 3,184E-03 0,02431665 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 3,184E-03 0,0242397 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 3,184E-03 0,02416324 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 3,184E-03 0,02408725 ! cGMP-mediated signaling GO:0019934 13 6 0,000 3,184E-03 0,02401174 ! activation of MAPKKK activity GO:0000185 12 6 0,000 3,184E-03 0,02393671 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 3,184E-03 0,02386214 ! thymic T cell selection GO:0045061 12 6 0,000 3,184E-03 0,02378803 ! protein lipoylation GO:0009249 10 6 0,000 3,184E-03 0,02371438 ! cysteine metabolic process GO:0006534 10 6 0,000 3,184E-03 0,02364119 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 3,184E-03 0,02356845 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 3,184E-03 0,02349615 ! glutamate catabolic process GO:0006538 10 6 0,000 3,184E-03 0,0234243 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 3,184E-03 0,02335288 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 3,184E-03 0,0232819 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 3,184E-03 0,02321135 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 3,184E-03 0,02314123 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 3,184E-03 0,02307152 ! hyperosmotic response GO:0006972 9 6 0,000 3,184E-03 0,02300224 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 3,184E-03 0,02293337 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 3,184E-03 0,02286491 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 3,184E-03 0,02279686 ! urea metabolic process GO:0019627 7 6 0,000 3,184E-03 0,02272922 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 3,184E-03 0,02266197 ! neutrophil activation GO:0042119 8 6 0,000 3,184E-03 0,02259512 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 3,184E-03 0,02252866 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 3,184E-03 0,0224626 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 3,184E-03 0,02239692 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 3,184E-03 0,02233162 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 3,184E-03 0,0222667 ! neuron apoptosis GO:0051402 9 6 0,000 3,184E-03 0,02220216 ! nucleoside salvage GO:0043174 9 6 0,000 3,184E-03 0,02213799 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 3,184E-03 0,0220742 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 3,184E-03 0,02201076 ! T cell mediated immunity GO:0002456 16 6 0,000 3,184E-03 0,0219477 ! negative regulation of platelet activation GO:0010544 9 6 0,000 3,184E-03 0,02188499 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 3,184E-03 0,02182264 ! carnitine transport GO:0015879 10 6 0,000 3,184E-03 0,02176064 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 3,184E-03 0,021699 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 3,184E-03 0,0216377 ! positive regulation of exocytosis GO:0045921 8 6 0,000 3,184E-03 0,02157675 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 3,184E-03 0,02151614 ! 5S class rRNA transcription GO:0042791 11 6 0,000 3,184E-03 0,02145587 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 3,184E-03 0,02139594 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 3,184E-03 0,02133634 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 3,184E-03 0,02127707 ! sodium ion homeostasis GO:0055078 11 6 0,000 3,184E-03 0,02121813 ! establishment of spindle localization GO:0051293 12 6 0,000 3,184E-03 0,02115952 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 3,184E-03 0,02110123 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 3,184E-03 0,02104326 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 3,184E-03 0,02098561 ! neural nucleus development GO:0048857 14 6 0,000 3,184E-03 0,02092827 ! response to UV-C GO:0010225 11 6 0,000 3,184E-03 0,02087124 ! astrocyte development GO:0014002 15 6 0,000 3,184E-03 0,02081453 ! protein targeting to lysosome GO:0006622 10 6 0,000 3,184E-03 0,02075812 ! purine base biosynthetic process GO:0009113 17 6 0,000 3,184E-03 0,02070202 ! interaction with symbiont GO:0051702 13 6 0,000 3,184E-03 0,02064622 ! regulation of dendrite development GO:0050773 16 6 0,000 3,184E-03 0,02059072 ! skeletal muscle contraction GO:0003009 6 6 0,000 3,184E-03 0,02053551 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 3,184E-03 0,0204806 ! response to copper ion GO:0046688 10 6 0,000 3,184E-03 0,02042599 ! response to exogenous dsRNA GO:0043330 10 6 0,000 3,184E-03 0,02037166 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 3,184E-03 0,02031763 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 3,184E-03 0,02026388 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 3,184E-03 0,02021041 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 3,184E-03 0,02015723 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 3,184E-03 0,02010432 ! regulation of dopamine secretion GO:0014059 14 6 0,000 3,184E-03 0,02005169 ! nucleoside catabolic process GO:0009164 7 6 0,000 3,184E-03 0,01999934 ! hair follicle maturation GO:0048820 7 6 0,000 3,184E-03 0,01994726 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 3,184E-03 0,01989544 ! Schwann cell development GO:0014044 15 6 0,000 3,184E-03 0,0198439 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 3,184E-03 0,01979263 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 3,184E-03 0,01974161 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 3,184E-03 0,01969086 ! subpallium development GO:0021544 10 6 0,000 3,184E-03 0,01964037 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 3,184E-03 0,01959014 ! histone ubiquitination GO:0016574 8 6 0,000 3,184E-03 0,01954017 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 3,184E-03 0,01949045 ! maintenance of organ identity GO:0048496 9 6 0,000 3,184E-03 0,01944098 ! G2 phase GO:0051319 16 6 0,000 3,184E-03 0,01939176 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 3,184E-03 0,01934279 ! establishment of planar polarity GO:0001736 7 6 0,000 3,184E-03 0,01929407 ! regulation of mast cell activation GO:0033003 12 6 0,000 3,184E-03 0,01924559 ! membrane to membrane docking GO:0022614 14 6 0,000 3,184E-03 0,01919736 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 3,184E-03 0,01914937 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 3,184E-03 0,01910161 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 3,184E-03 0,01905409 ! receptor internalization GO:0031623 10 6 0,000 3,184E-03 0,01900681 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 3,184E-03 0,01895977 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 3,184E-03 0,01891295 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 3,184E-03 0,01886637 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 3,184E-03 0,01882001 ! protein deubiquitination GO:0016579 14 6 0,000 3,184E-03 0,01877389 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 3,184E-03 0,01872799 ! protein destabilization GO:0031648 9 6 0,000 3,184E-03 0,01868231 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 3,184E-03 0,01863685 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 3,184E-03 0,01859162 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 3,184E-03 0,0185466 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 3,184E-03 0,0185018 ! progesterone metabolic process GO:0042448 10 6 0,000 3,184E-03 0,01845722 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 3,184E-03 0,01841285 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 3,184E-03 0,0183687 ! negative regulation of axon extension GO:0030517 21 6 0,000 3,184E-03 0,01832475 ! removal of superoxide radicals GO:0019430 11 6 0,000 3,184E-03 0,01828102 ! triglyceride catabolic process GO:0019433 10 6 0,000 3,184E-03 0,01823749 ! determination of adult lifespan GO:0008340 15 6 0,000 3,184E-03 0,01819417 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 3,184E-03 0,01815106 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 3,184E-03 0,01810815 ! cerebellar cortex formation GO:0021697 8 6 0,000 3,184E-03 0,01806544 ! catecholamine transport GO:0051937 9 6 0,000 3,184E-03 0,01802293 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 3,184E-03 0,01798062 ! sensory cilium assembly GO:0035058 10 6 0,000 3,184E-03 0,01793852 ! organ or tissue specific immune response GO:0002251 7 6 0,000 3,184E-03 0,0178966 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 3,184E-03 0,01785489 ! maternal placenta development GO:0001893 12 6 0,000 3,184E-03 0,01781336 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 3,184E-03 0,01777203 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 3,184E-03 0,01773089 ! negative regulation of B cell activation GO:0050869 13 6 0,000 3,184E-03 0,01768994 ! protein amino acid prenylation GO:0018346 16 6 0,000 3,184E-03 0,01764918 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 3,184E-03 0,01760861 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 3,184E-03 0,01756822 ! positive regulation of coagulation GO:0050820 12 6 0,000 3,184E-03 0,01752802 ! tRNA transcription GO:0009304 14 7 0,000 3,713E-03 0,02039759 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 3,713E-03 0,02035113 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 3,713E-03 0,02030488 ! behavioral response to cocaine GO:0048148 14 7 0,000 3,713E-03 0,02025883 ! regulation of helicase activity GO:0051095 15 7 0,000 3,713E-03 0,020213 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 3,713E-03 0,02016737 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 3,713E-03 0,02012195 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 3,713E-03 0,02007673 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 3,713E-03 0,02003172 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 3,713E-03 0,0199869 ! prostate gland development GO:0030850 13 7 0,000 3,713E-03 0,01994229 ! nucleotide-sugar transport GO:0015780 12 7 0,000 3,713E-03 0,01989787 ! synaptonemal complex assembly GO:0007130 10 7 0,000 3,713E-03 0,01985366 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 3,713E-03 0,01980964 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 3,713E-03 0,01976581 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 3,713E-03 0,01972218 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 3,713E-03 0,01967873 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 3,713E-03 0,01963548 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 3,713E-03 0,01959242 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 3,713E-03 0,01954955 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 3,713E-03 0,01950687 ! SMAD protein complex assembly GO:0007183 12 7 0,000 3,713E-03 0,01946437 ! glycolipid transport GO:0046836 10 7 0,000 3,713E-03 0,01942206 ! protein amino acid sulfation GO:0006477 10 7 0,000 3,713E-03 0,01937993 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 3,713E-03 0,01933798 ! neuron adhesion GO:0007158 12 7 0,000 3,713E-03 0,01929621 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 3,713E-03 0,01925462 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 3,713E-03 0,01921322 ! actin-myosin filament sliding GO:0033275 11 7 0,000 3,713E-03 0,01917199 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 3,713E-03 0,01913093 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 3,713E-03 0,01909005 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 3,713E-03 0,01904935 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 3,713E-03 0,01900882 ! mRNA stabilization GO:0048255 18 7 0,000 3,713E-03 0,01896846 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 3,713E-03 0,01892827 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 3,713E-03 0,01888826 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 3,713E-03 0,01884841 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 3,713E-03 0,01880873 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 3,713E-03 0,01876921 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 3,713E-03 0,01872986 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 3,713E-03 0,01869068 ! lipoprotein transport GO:0042953 14 7 0,000 3,713E-03 0,01865166 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 3,713E-03 0,0186128 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 3,713E-03 0,01857411 ! rhythmic behavior GO:0007622 15 7 0,000 3,713E-03 0,01853557 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 3,713E-03 0,0184972 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 3,713E-03 0,01845898 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 3,713E-03 0,01842092 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 3,713E-03 0,01838302 ! regulation of odontogenesis GO:0042481 13 7 0,000 3,713E-03 0,01834527 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 3,713E-03 0,01830768 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 3,713E-03 0,01827024 ! mechanosensory behavior GO:0007638 14 7 0,000 3,713E-03 0,01823295 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 3,713E-03 0,01819582 ! positive regulation of isotype switching GO:0045830 15 7 0,000 3,713E-03 0,01815883 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 3,713E-03 0,018122 ! protein-cofactor linkage GO:0018065 13 7 0,000 3,713E-03 0,01808531 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 3,713E-03 0,01804878 ! spinal cord patterning GO:0021511 13 7 0,000 3,713E-03 0,01801239 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 3,713E-03 0,01797615 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 3,713E-03 0,01794005 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 3,713E-03 0,0179041 ! adrenal gland development GO:0030325 17 7 0,000 3,713E-03 0,01786829 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 3,713E-03 0,01783263 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 3,713E-03 0,0177971 ! ovulation GO:0030728 9 7 0,000 3,713E-03 0,01776172 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 3,713E-03 0,01772648 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 3,713E-03 0,01769138 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 3,713E-03 0,01765641 ! microtubule nucleation GO:0007020 20 7 0,000 3,713E-03 0,01762159 ! proline biosynthetic process GO:0006561 10 7 0,000 3,713E-03 0,0175869 ! thyroid hormone generation GO:0006590 13 7 0,000 3,713E-03 0,01755235 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 3,713E-03 0,01751793 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 3,713E-03 0,01748365 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 3,713E-03 0,0174495 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 3,713E-03 0,01741549 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 3,713E-03 0,01738161 ! galactose metabolic process GO:0006012 13 7 0,000 3,713E-03 0,01734786 ! vesicle fusion GO:0006906 17 7 0,000 3,713E-03 0,01731424 ! response to dietary excess GO:0002021 8 7 0,000 3,713E-03 0,01728075 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 3,713E-03 0,01724739 ! intracellular pH reduction GO:0051452 11 7 0,000 3,713E-03 0,01721415 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 3,713E-03 0,01718105 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 3,713E-03 0,01714807 ! organ growth GO:0035265 15 7 0,000 3,713E-03 0,01711522 ! purine salvage GO:0043101 10 7 0,000 3,713E-03 0,0170825 ! nucleoside transport GO:0015858 8 7 0,000 3,713E-03 0,0170499 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 3,713E-03 0,01701742 ! parturition GO:0007567 14 7 0,000 3,713E-03 0,01698507 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 3,713E-03 0,01695284 ! rRNA modification GO:0000154 14 7 0,000 3,713E-03 0,01692073 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 3,713E-03 0,01688874 ! spindle checkpoint GO:0031577 15 7 0,000 3,713E-03 0,01685688 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 3,713E-03 0,01682513 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 3,713E-03 0,01679351 ! macrophage differentiation GO:0030225 11 7 0,000 3,713E-03 0,016762 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 3,713E-03 0,01673061 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 3,713E-03 0,01669934 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 3,713E-03 0,01666818 ! hyaluronan metabolic process GO:0030212 8 7 0,000 3,713E-03 0,01663714 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 3,713E-03 0,01660622 ! anterograde axon cargo transport GO:0008089 18 7 0,000 3,713E-03 0,01657541 ! fibrinolysis GO:0042730 10 7 0,000 3,713E-03 0,01654471 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 3,713E-03 0,01651413 ! eating behavior GO:0042755 7 7 0,000 3,713E-03 0,01648366 ! B cell lineage commitment GO:0002326 21 7 0,000 3,713E-03 0,01645331 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 3,713E-03 0,01642306 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 3,713E-03 0,01639293 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 3,713E-03 0,0163629 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 3,713E-03 0,01633299 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 3,713E-03 0,01630319 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 3,713E-03 0,01627349 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 3,713E-03 0,0162439 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 3,713E-03 0,01621442 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 3,713E-03 0,01618505 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 3,713E-03 0,01615578 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 3,713E-03 0,01612662 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 3,713E-03 0,01609756 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 3,713E-03 0,01606861 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 3,713E-03 0,01603976 ! regulation of meiosis GO:0040020 12 7 0,000 3,713E-03 0,01601101 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 3,713E-03 0,01598237 ! T cell lineage commitment GO:0002360 16 7 0,000 3,713E-03 0,01595383 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 3,713E-03 0,01592539 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 3,713E-03 0,01589706 ! oxygen homeostasis GO:0032364 12 7 0,000 3,713E-03 0,01586882 ! transcription termination GO:0006353 13 7 0,000 3,713E-03 0,01584068 ! response to tumor cell GO:0002347 13 7 0,000 3,713E-03 0,01581265 ! regulation of respiratory burst GO:0060263 11 7 0,000 3,713E-03 0,01578471 ! coenzyme A metabolic process GO:0015936 12 7 0,000 3,713E-03 0,01575687 ! anaphase GO:0051322 17 7 0,000 3,713E-03 0,01572913 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 3,713E-03 0,01570149 ! axonal fasciculation GO:0007413 18 7 0,000 3,713E-03 0,01567394 ! negative regulation of nuclear division GO:0051784 14 7 0,000 3,713E-03 0,01564649 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 3,713E-03 0,01561914 ! peptidyl-threonine modification GO:0018210 25 7 0,000 3,713E-03 0,01559188 ! diuresis GO:0030146 12 7 0,000 3,713E-03 0,01556471 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 3,713E-03 0,01553764 ! thiamin metabolic process GO:0006772 7 7 0,000 3,713E-03 0,01551067 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 3,713E-03 0,01548379 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 3,713E-03 0,015457 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 3,713E-03 0,0154303 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 3,713E-03 0,0154037 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 3,713E-03 0,01537719 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 3,713E-03 0,01535077 ! melanin biosynthetic process GO:0042438 8 7 0,000 3,713E-03 0,01532443 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 3,713E-03 0,01529819 ! dopamine biosynthetic process GO:0042416 18 7 0,000 3,713E-03 0,01527204 ! glycolipid catabolic process GO:0019377 15 7 0,000 3,713E-03 0,01524598 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 3,713E-03 0,01522001 ! lymph node development GO:0048535 10 7 0,000 3,713E-03 0,01519413 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 3,713E-03 0,01516833 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 3,713E-03 0,01514262 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 3,713E-03 0,015117 ! endosome to lysosome transport GO:0008333 11 7 0,000 3,713E-03 0,01509146 ! protein modification by small protein removal GO:0070646 16 7 0,000 3,713E-03 0,01506601 ! adult feeding behavior GO:0008343 9 7 0,000 3,713E-03 0,01504065 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 3,713E-03 0,01501537 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 3,713E-03 0,01499018 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 3,713E-03 0,01496507 ! muscle adaptation GO:0043500 14 7 0,000 3,713E-03 0,01494004 ! embryonic heart tube development GO:0035050 10 7 0,000 3,713E-03 0,0149151 ! retina homeostasis GO:0001895 12 7 0,000 3,713E-03 0,01489024 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 3,713E-03 0,01486547 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 3,713E-03 0,01484077 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 3,713E-03 0,01481616 ! protein prenylation GO:0018342 18 7 0,000 3,713E-03 0,01479163 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 3,713E-03 0,01476718 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 3,713E-03 0,01474281 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 3,713E-03 0,01471853 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 4,243E-03 0,01678933 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 4,243E-03 0,01676176 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 4,243E-03 0,01673428 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 4,243E-03 0,01670689 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 4,243E-03 0,01667959 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 4,243E-03 0,01665238 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 4,243E-03 0,01662526 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 4,243E-03 0,01659823 ! neutral lipid catabolic process GO:0046461 13 8 0,000 4,243E-03 0,01657128 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 4,243E-03 0,01654442 ! meiotic prophase I GO:0007128 13 8 0,000 4,243E-03 0,01651765 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 4,243E-03 0,01649097 ! oligopeptide transport GO:0006857 15 8 0,000 4,243E-03 0,01646437 ! UTP metabolic process GO:0046051 8 8 0,000 4,243E-03 0,01643786 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 4,243E-03 0,01641143 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 4,243E-03 0,01638509 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 4,243E-03 0,01635883 ! macrophage chemotaxis GO:0048246 12 8 0,000 4,243E-03 0,01633266 ! succinate metabolic process GO:0006105 14 8 0,000 4,243E-03 0,01630657 ! membrane hyperpolarization GO:0060081 10 8 0,000 4,243E-03 0,01628056 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 4,243E-03 0,01625463 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 4,243E-03 0,01622879 ! T-helper 1 type immune response GO:0042088 12 8 0,000 4,243E-03 0,01620303 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 4,243E-03 0,01617735 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 4,243E-03 0,01615176 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 4,243E-03 0,01612624 ! ganglioside metabolic process GO:0001573 19 8 0,000 4,243E-03 0,0161008 ! reflex GO:0060004 16 8 0,000 4,243E-03 0,01607545 ! negative regulation of endocytosis GO:0045806 11 8 0,000 4,243E-03 0,01605017 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 4,243E-03 0,01602498 ! endothelial cell differentiation GO:0045446 17 8 0,000 4,243E-03 0,01599986 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 4,243E-03 0,01597482 ! glycerolipid catabolic process GO:0046503 13 8 0,000 4,243E-03 0,01594986 ! hemoglobin metabolic process GO:0020027 13 8 0,000 4,243E-03 0,01592498 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 4,243E-03 0,01590017 ! pigment granule organization GO:0048753 16 8 0,000 4,243E-03 0,01587544 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 4,243E-03 0,01585079 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 4,243E-03 0,01582622 ! astrocyte differentiation GO:0048708 18 8 0,000 4,243E-03 0,01580172 ! histidine metabolic process GO:0006547 16 8 0,000 4,243E-03 0,0157773 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 4,243E-03 0,01575295 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 4,243E-03 0,01572868 ! glycine catabolic process GO:0006546 13 8 0,000 4,243E-03 0,01570448 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 4,243E-03 0,01568035 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 4,243E-03 0,0156563 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 4,243E-03 0,01563233 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 4,243E-03 0,01560843 ! regulation of pigmentation during development GO:0048070 24 8 0,000 4,243E-03 0,0155846 ! melanin metabolic process GO:0006582 15 8 0,000 4,243E-03 0,01556084 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 4,243E-03 0,01553715 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 4,243E-03 0,01551354 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 4,243E-03 0,01549 ! macrophage activation GO:0042116 12 8 0,000 4,243E-03 0,01546653 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 4,243E-03 0,01544313 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 4,243E-03 0,0154198 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 4,243E-03 0,01539655 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 4,243E-03 0,01537336 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 4,243E-03 0,01535024 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 4,243E-03 0,01532719 ! regulation of vascular permeability GO:0043114 12 8 0,000 4,243E-03 0,01530421 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 4,243E-03 0,0152813 ! osteoblast development GO:0002076 16 8 0,000 4,243E-03 0,01525846 ! positive regulation of vasodilation GO:0045909 13 8 0,000 4,243E-03 0,01523569 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 4,243E-03 0,01521298 ! negative regulation of translational initiation GO:0045947 10 8 0,000 4,243E-03 0,01519034 ! Schwann cell differentiation GO:0014037 19 8 0,000 4,243E-03 0,01516777 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 4,243E-03 0,01514527 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 4,243E-03 0,01512283 ! response to UV-B GO:0010224 16 8 0,000 4,243E-03 0,01510046 ! protein targeting to vacuole GO:0006623 12 8 0,000 4,243E-03 0,01507815 ! protein retention in ER lumen GO:0006621 14 8 0,000 4,243E-03 0,01505591 ! intermediate filament organization GO:0045109 12 8 0,000 4,243E-03 0,01503374 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 4,243E-03 0,01501163 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 4,243E-03 0,01498959 ! cellular extravasation GO:0045123 12 8 0,000 4,243E-03 0,01496761 ! cardiac muscle cell development GO:0055013 13 8 0,000 4,243E-03 0,0149457 ! regulation of circadian rhythm GO:0042752 16 8 0,000 4,243E-03 0,01492385 ! response to antibiotic GO:0046677 11 8 0,000 4,243E-03 0,01490206 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 4,243E-03 0,01488034 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 4,243E-03 0,01485868 ! DNA topological change GO:0006265 12 8 0,000 4,243E-03 0,01483708 ! response to tropane GO:0014073 15 8 0,000 4,243E-03 0,01481554 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 4,243E-03 0,01479407 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 4,243E-03 0,01477266 ! melanosome transport GO:0032402 13 8 0,000 4,243E-03 0,01475132 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 0,000 4,243E-03 0,01473003 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 4,243E-03 0,0147088 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 4,243E-03 0,01468764 ! mast cell activation GO:0045576 14 8 0,000 4,243E-03 0,01466654 ! multicellular organismal aging GO:0010259 18 8 0,000 4,243E-03 0,0146455 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 4,243E-03 0,01462451 ! dendrite morphogenesis GO:0048813 13 8 0,000 4,243E-03 0,01460359 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 4,243E-03 0,01458273 ! nucleosome disassembly GO:0006337 14 8 0,000 4,243E-03 0,01456193 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 4,243E-03 0,01454118 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 4,243E-03 0,0145205 ! leukocyte activation during immune response GO:0002366 13 8 0,000 4,243E-03 0,01449987 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 4,243E-03 0,01447931 ! establishment of chromosome localization GO:0051303 12 8 0,000 4,243E-03 0,0144588 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 4,243E-03 0,01443835 ! intracellular lipid transport GO:0032365 13 8 0,000 4,243E-03 0,01441795 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 4,243E-03 0,01439762 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 4,243E-03 0,01437734 ! regulation of macrophage activation GO:0043030 15 8 0,000 4,243E-03 0,01435712 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 4,243E-03 0,01433695 ! positive regulation of epidermis development GO:0045684 13 8 0,000 4,243E-03 0,01431684 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 4,243E-03 0,01429679 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 4,243E-03 0,0142768 ! hormone catabolic process GO:0042447 17 8 0,000 4,243E-03 0,01425686 ! positive regulation of glucose import GO:0046326 8 8 0,000 4,243E-03 0,01423697 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 4,243E-03 0,01421715 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 4,243E-03 0,01419737 ! ATP catabolic process GO:0006200 11 8 0,000 4,243E-03 0,01417765 ! blastocyst growth GO:0001832 19 8 0,000 4,243E-03 0,01415799 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 4,243E-03 0,01413838 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 4,243E-03 0,01411882 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 4,243E-03 0,01409932 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 4,243E-03 0,01407988 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 4,243E-03 0,01406048 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 4,243E-03 0,01404114 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 4,243E-03 0,01402185 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 4,243E-03 0,01400262 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 4,243E-03 0,01398344 ! amino sugar catabolic process GO:0046348 10 8 0,000 4,243E-03 0,01396431 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 4,243E-03 0,01394523 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 4,243E-03 0,01392621 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 4,243E-03 0,01390723 ! behavioral response to nicotine GO:0035095 12 8 0,000 4,243E-03 0,01388831 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 4,243E-03 0,01386944 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 4,243E-03 0,01385062 ! NAD biosynthetic process GO:0009435 13 8 0,000 4,243E-03 0,01383186 ! regulation of developmental growth GO:0048638 15 9 0,000 4,772E-03 0,01553591 ! axon extension GO:0048675 15 9 0,000 4,772E-03 0,01551492 ! autophagic vacuole formation GO:0000045 15 9 0,000 4,772E-03 0,01549398 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 4,772E-03 0,0154731 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 4,772E-03 0,01545227 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 4,772E-03 0,01543151 ! pentose-phosphate shunt GO:0006098 16 9 0,000 4,772E-03 0,01541079 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 4,772E-03 0,01539013 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 4,772E-03 0,01536953 ! cell proliferation in forebrain GO:0021846 15 9 0,000 4,772E-03 0,01534898 ! phosphate transport GO:0006817 19 9 0,000 4,772E-03 0,01532849 ! reproductive behavior GO:0019098 19 9 0,000 4,772E-03 0,01530805 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 4,772E-03 0,01528767 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 4,772E-03 0,01526734 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 4,772E-03 0,01524707 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 4,772E-03 0,01522684 ! GTP metabolic process GO:0046039 9 9 0,000 4,772E-03 0,01520668 ! RNA methylation GO:0001510 15 9 0,000 4,772E-03 0,01518656 ! elastic fiber assembly GO:0048251 15 9 0,000 4,772E-03 0,0151665 ! induction of positive chemotaxis GO:0050930 15 9 0,000 4,772E-03 0,01514649 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 4,772E-03 0,01512654 ! artery development GO:0060840 24 9 0,000 4,772E-03 0,01510663 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 4,772E-03 0,01508678 ! regulation of glycolysis GO:0006110 21 9 0,000 4,772E-03 0,01506698 ! cerebral cortex cell migration GO:0021795 15 9 0,000 4,772E-03 0,01504723 ! keratinocyte proliferation GO:0043616 14 9 0,000 4,772E-03 0,01502754 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 4,772E-03 0,0150079 ! chemosensory behavior GO:0007635 20 9 0,000 4,772E-03 0,0149883 ! microtubule bundle formation GO:0001578 21 9 0,000 4,772E-03 0,01496876 ! middle ear morphogenesis GO:0042474 14 9 0,000 4,772E-03 0,01494927 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 4,772E-03 0,01492983 ! leukocyte degranulation GO:0043299 16 9 0,000 4,772E-03 0,01491044 ! bile acid and bile salt transport GO:0015721 13 9 0,000 4,772E-03 0,0148911 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 4,772E-03 0,01487181 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 4,772E-03 0,01485257 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 4,772E-03 0,01483339 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 4,772E-03 0,01481425 ! protein targeting to ER GO:0045047 22 9 0,000 4,772E-03 0,01479515 ! ceramide biosynthetic process GO:0046513 19 9 0,000 4,772E-03 0,01477611 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 4,772E-03 0,01475712 ! T cell selection GO:0045058 23 9 0,000 4,772E-03 0,01473818 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 4,772E-03 0,01471928 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 4,772E-03 0,01470044 ! phosphagen metabolic process GO:0006599 12 9 0,000 4,772E-03 0,01468164 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 4,772E-03 0,01466289 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 4,772E-03 0,01464418 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 4,772E-03 0,01462553 ! regulation of type I interferon production GO:0032479 12 9 0,000 4,772E-03 0,01460692 ! mannose metabolic process GO:0006013 13 9 0,000 4,772E-03 0,01458836 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 4,772E-03 0,01456985 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 4,772E-03 0,01455138 ! Rac protein signal transduction GO:0016601 17 9 0,000 4,772E-03 0,01453296 ! receptor clustering GO:0043113 18 9 0,000 4,772E-03 0,01451459 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 4,772E-03 0,01449626 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 4,772E-03 0,01447798 ! ruffle organization GO:0031529 15 9 0,000 4,772E-03 0,01445975 ! retinol metabolic process GO:0042572 18 9 0,000 4,772E-03 0,01444156 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 4,772E-03 0,01442342 ! behavioral fear response GO:0001662 22 9 0,000 4,772E-03 0,01440532 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 4,772E-03 0,01438727 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 4,772E-03 0,01436926 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 4,772E-03 0,0143513 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 4,772E-03 0,01433338 ! protein heterooligomerization GO:0051291 16 9 0,000 4,772E-03 0,01431551 ! oligodendrocyte development GO:0014003 10 9 0,000 4,772E-03 0,01429768 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 4,772E-03 0,0142799 ! segment specification GO:0007379 13 9 0,000 4,772E-03 0,01426216 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 4,772E-03 0,01424447 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 4,772E-03 0,01422682 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 4,772E-03 0,01420921 ! response to amine stimulus GO:0014075 13 9 0,000 4,772E-03 0,01419164 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 4,772E-03 0,01417412 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 4,772E-03 0,01415665 ! erythrocyte development GO:0048821 15 9 0,000 4,772E-03 0,01413921 ! gas homeostasis GO:0033483 16 9 0,000 4,772E-03 0,01412182 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 4,772E-03 0,01410447 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 4,772E-03 0,01408717 ! renal water homeostasis GO:0003091 14 9 0,000 4,772E-03 0,0140699 ! postreplication repair GO:0006301 22 9 0,000 4,772E-03 0,01405268 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 4,772E-03 0,0140355 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 4,772E-03 0,01401836 ! icosanoid secretion GO:0032309 15 9 0,000 4,772E-03 0,01400127 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 4,772E-03 0,01398421 ! cerebellum morphogenesis GO:0021587 14 9 0,000 4,772E-03 0,0139672 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 4,772E-03 0,01395023 ! regulation of cell division GO:0051302 15 9 0,000 4,772E-03 0,0139333 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 4,772E-03 0,01391641 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 4,772E-03 0,01389956 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 4,772E-03 0,01388276 ! sterol catabolic process GO:0016127 11 9 0,000 4,772E-03 0,01386599 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 4,772E-03 0,01384926 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 4,772E-03 0,01383258 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 4,772E-03 0,01381593 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 4,772E-03 0,01379933 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 4,772E-03 0,01378276 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 4,772E-03 0,01376624 ! musculoskeletal movement GO:0050881 14 9 0,000 4,772E-03 0,01374975 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 4,772E-03 0,0137333 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 4,772E-03 0,01371689 ! regulation of synaptogenesis GO:0051963 15 9 0,000 4,772E-03 0,01370053 ! purine base metabolic process GO:0006144 21 9 0,000 4,772E-03 0,0136842 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 4,772E-03 0,01366791 ! pigment granule transport GO:0051904 17 9 0,000 4,772E-03 0,01365165 ! regulation of fibrinolysis GO:0051917 16 9 0,000 4,772E-03 0,01363544 ! regulation of telomere maintenance GO:0032204 14 9 0,000 4,772E-03 0,01361926 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 4,772E-03 0,01360313 ! regulation of muscle adaptation GO:0043502 14 9 0,000 4,772E-03 0,01358703 ! regulation of amino acid transport GO:0051955 11 9 0,000 4,772E-03 0,01357097 ! mitochondrion localization GO:0051646 15 9 0,000 4,772E-03 0,01355495 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 5,301E-03 0,01503955 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 5,301E-03 0,01502183 ! negative regulation of blood pressure GO:0045776 26 10 0,000 5,301E-03 0,01500416 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 5,301E-03 0,01498653 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 5,301E-03 0,01496894 ! regulation of phosphatase activity GO:0010921 28 10 0,000 5,301E-03 0,01495139 ! synapsis GO:0007129 13 10 0,000 5,301E-03 0,01493388 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 20 10 0,000 5,301E-03 0,01491642 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 5,301E-03 0,01489899 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 5,301E-03 0,01488161 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 5,301E-03 0,01486426 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 5,301E-03 0,01484696 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 5,301E-03 0,01482969 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 5,301E-03 0,01481247 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 5,301E-03 0,01479529 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 5,301E-03 0,01477814 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 5,301E-03 0,01476104 ! androgen metabolic process GO:0008209 17 10 0,000 5,301E-03 0,01474397 ! phospholipid efflux GO:0033700 16 10 0,000 5,301E-03 0,01472695 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 5,301E-03 0,01470996 ! positive regulation of heart contraction GO:0045823 16 10 0,000 5,301E-03 0,01469301 ! lung alveolus development GO:0048286 26 10 0,000 5,301E-03 0,01467611 ! pathogenesis GO:0009405 13 10 0,000 5,301E-03 0,01465924 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 5,301E-03 0,01464241 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 5,301E-03 0,01462561 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 5,301E-03 0,01460886 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 5,301E-03 0,01459215 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 5,301E-03 0,01457547 ! endoderm development GO:0007492 16 10 0,000 5,301E-03 0,01455883 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 5,301E-03 0,01454223 ! arginine catabolic process GO:0006527 13 10 0,000 5,301E-03 0,01452567 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 5,301E-03 0,01450914 ! proline metabolic process GO:0006560 13 10 0,000 5,301E-03 0,01449265 ! glucan biosynthetic process GO:0009250 14 10 0,000 5,301E-03 0,0144762 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 5,301E-03 0,01445979 ! polyamine biosynthetic process GO:0006596 12 10 0,000 5,301E-03 0,01444342 ! V(D)J recombination GO:0033151 28 10 0,000 5,301E-03 0,01442708 ! reverse cholesterol transport GO:0043691 16 10 0,000 5,301E-03 0,01441078 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 5,301E-03 0,01439451 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 5,301E-03 0,01437828 ! B cell proliferation GO:0042100 18 10 0,000 5,301E-03 0,01436209 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 5,301E-03 0,01434593 ! regulation of sodium ion transport GO:0002028 21 10 0,000 5,301E-03 0,01432982 ! multicellular organism growth GO:0035264 18 10 0,000 5,301E-03 0,01431373 ! phagocytosis, engulfment GO:0006911 28 10 0,000 5,301E-03 0,01429769 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 5,301E-03 0,01428168 ! epithelial cell development GO:0002064 20 10 0,000 5,301E-03 0,0142657 ! lens development in camera-type eye GO:0002088 16 10 0,000 5,301E-03 0,01424976 ! retinoic acid metabolic process GO:0042573 14 10 0,000 5,301E-03 0,01423386 ! macroautophagy GO:0016236 17 10 0,000 5,301E-03 0,01421799 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 5,301E-03 0,01420216 ! positive regulation of translational initiation GO:0045948 11 10 0,000 5,301E-03 0,01418636 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 5,301E-03 0,0141706 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 5,301E-03 0,01415487 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 5,301E-03 0,01413918 ! copper ion homeostasis GO:0055070 13 10 0,000 5,301E-03 0,01412352 ! regulation of bone resorption GO:0045124 25 10 0,000 5,301E-03 0,01410789 ! regulation of gliogenesis GO:0014013 23 10 0,000 5,301E-03 0,01409231 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 5,301E-03 0,01407675 ! alpha-beta T cell activation GO:0046631 23 10 0,000 5,301E-03 0,01406123 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 5,301E-03 0,01404574 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 5,301E-03 0,01403029 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 5,301E-03 0,01401487 ! blastoderm segmentation GO:0007350 18 10 0,000 5,301E-03 0,01399949 ! response to dsRNA GO:0043331 20 10 0,000 5,301E-03 0,01398414 ! DNA ligation GO:0006266 19 10 0,000 5,301E-03 0,01396882 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 5,301E-03 0,01395354 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 5,301E-03 0,01393829 ! melanosome localization GO:0032400 16 10 0,000 5,301E-03 0,01392307 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 5,301E-03 0,01390789 ! regulation of B cell differentiation GO:0045577 19 10 0,000 5,301E-03 0,01389274 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 5,301E-03 0,01387762 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 5,301E-03 0,01386254 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 5,301E-03 0,01384749 ! mRNA cleavage GO:0006379 17 10 0,000 5,301E-03 0,01383247 ! protein sumoylation GO:0016925 15 10 0,000 5,301E-03 0,01381748 ! hindbrain morphogenesis GO:0021575 19 10 0,000 5,301E-03 0,01380253 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 5,301E-03 0,01378761 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 5,301E-03 0,01377272 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 5,301E-03 0,01375786 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 5,301E-03 0,01374303 ! salivary gland development GO:0007431 27 10 0,000 5,301E-03 0,01372824 ! prophase GO:0051324 15 10 0,000 5,301E-03 0,01371348 ! negative regulation of neurological system process GO:0031645 19 10 0,000 5,301E-03 0,01369875 ! apical protein localization GO:0045176 15 10 0,000 5,301E-03 0,01368405 ! ubiquinone metabolic process GO:0006743 15 10 0,000 5,301E-03 0,01366938 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 5,301E-03 0,01365475 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 5,301E-03 0,01364015 ! midbrain development GO:0030901 13 10 0,000 5,301E-03 0,01362557 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 5,301E-03 0,01361103 ! methionine biosynthetic process GO:0009086 19 10 0,000 5,301E-03 0,01359652 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 5,301E-03 0,01358204 ! quaternary ammonium group transport GO:0015697 21 10 0,000 5,301E-03 0,01356759 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 5,301E-03 0,01355317 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 5,301E-03 0,01353879 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 5,301E-03 0,01352443 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 5,301E-03 0,0135101 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 5,301E-03 0,01349581 ! oocyte development GO:0048599 17 10 0,000 5,301E-03 0,01348154 ! establishment of pigment granule localization GO:0051905 18 10 0,000 5,301E-03 0,0134673 ! blastocyst formation GO:0001825 17 10 0,000 5,301E-03 0,0134531 ! cerebellar cortex development GO:0021695 15 10 0,000 5,301E-03 0,01343892 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 5,301E-03 0,01342477 ! activation of innate immune response GO:0002218 12 10 0,000 5,301E-03 0,01341066 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 5,301E-03 0,01339657 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 5,301E-03 0,01338251 ! response to nicotine GO:0035094 20 10 0,000 5,301E-03 0,01336849 ! establishment of cell polarity GO:0030010 16 10 0,000 5,301E-03 0,01335449 ! negative regulation of immune effector process GO:0002698 20 10 0,000 5,301E-03 0,01334052 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 5,301E-03 0,01332658 ! localization within membrane GO:0051668 20 10 0,000 5,301E-03 0,01331267 ! negative regulation of muscle development GO:0048635 20 11 0,000 5,829E-03 0,01462502 ! respiratory burst GO:0045730 17 11 0,000 5,829E-03 0,01460979 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 5,829E-03 0,01459459 ! neuron fate specification GO:0048665 17 11 0,000 5,829E-03 0,01457942 ! telencephalon cell migration GO:0022029 20 11 0,000 5,829E-03 0,01456428 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 5,829E-03 0,01454917 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 5,829E-03 0,01453409 ! thyroid gland development GO:0030878 26 11 0,000 5,829E-03 0,01451905 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 5,829E-03 0,01450403 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 5,829E-03 0,01448905 ! Golgi vesicle budding GO:0048194 22 11 0,000 5,829E-03 0,01447409 ! response to pain GO:0048265 24 11 0,000 5,829E-03 0,01445917 ! detection of mechanical stimulus GO:0050982 22 11 0,000 5,829E-03 0,01444428 ! T cell proliferation GO:0042098 26 11 0,000 5,829E-03 0,01442942 ! blood vessel remodeling GO:0001974 29 11 0,000 5,829E-03 0,01441459 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 5,829E-03 0,01439979 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 5,829E-03 0,01438502 ! bone resorption GO:0045453 16 11 0,000 5,829E-03 0,01437028 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 5,829E-03 0,01435558 ! ventral spinal cord development GO:0021517 21 11 0,000 5,829E-03 0,0143409 ! negative regulation of proteolysis GO:0045861 25 11 0,000 5,829E-03 0,01432625 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 5,829E-03 0,01431163 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 5,829E-03 0,01429704 ! melanocyte differentiation GO:0030318 21 11 0,000 5,829E-03 0,01428248 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 5,829E-03 0,01426795 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 5,829E-03 0,01425345 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 5,829E-03 0,01423898 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 5,829E-03 0,01422454 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 5,829E-03 0,01421013 ! lipid digestion GO:0044241 18 11 0,000 5,829E-03 0,01419575 ! substrate-bound cell migration GO:0006929 13 11 0,000 5,829E-03 0,01418139 ! UV protection GO:0009650 19 11 0,000 5,829E-03 0,01416707 ! adult heart development GO:0007512 14 11 0,000 5,829E-03 0,01415277 ! chondrocyte differentiation GO:0002062 24 11 0,000 5,829E-03 0,01413851 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 5,829E-03 0,01412427 ! temperature homeostasis GO:0001659 17 11 0,000 5,829E-03 0,01411006 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 5,829E-03 0,01409588 ! negative regulation of ossification GO:0030279 26 11 0,000 5,829E-03 0,01408172 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 5,829E-03 0,0140676 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 5,829E-03 0,0140535 ! regulation of organ growth GO:0046620 13 11 0,000 5,829E-03 0,01403944 ! pigment granule localization GO:0051875 20 11 0,000 5,829E-03 0,0140254 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 5,829E-03 0,01401139 ! vasoconstriction GO:0042310 18 11 0,000 5,829E-03 0,0139974 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 5,829E-03 0,01398345 ! embryonic axis specification GO:0000578 18 11 0,000 5,829E-03 0,01396952 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 5,829E-03 0,01395562 ! snRNA metabolic process GO:0016073 24 11 0,000 5,829E-03 0,01394175 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 5,829E-03 0,0139279 ! nitric oxide metabolic process GO:0046209 15 11 0,000 5,829E-03 0,01391409 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 5,829E-03 0,0139003 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 5,829E-03 0,01388653 ! zymogen activation GO:0031638 15 11 0,000 5,829E-03 0,0138728 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 5,829E-03 0,01385909 ! neuroblast proliferation GO:0007405 24 11 0,000 5,829E-03 0,01384541 ! nucleosome positioning GO:0016584 15 11 0,000 5,829E-03 0,01383175 ! regulation of isotype switching GO:0045191 22 11 0,000 5,829E-03 0,01381813 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 5,829E-03 0,01380453 ! glutathione biosynthetic process GO:0006750 13 11 0,000 5,829E-03 0,01379095 ! regulation of leukocyte migration GO:0002685 26 11 0,000 5,829E-03 0,0137774 ! acid secretion GO:0046717 18 11 0,000 5,829E-03 0,01376388 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 5,829E-03 0,01375039 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 5,829E-03 0,01373692 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 5,829E-03 0,01372348 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 5,829E-03 0,01371007 ! oocyte differentiation GO:0009994 18 11 0,000 5,829E-03 0,01369668 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 5,829E-03 0,01368331 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 5,829E-03 0,01366998 ! cholesterol efflux GO:0033344 19 11 0,000 5,829E-03 0,01365667 ! anterior/posterior axis specification GO:0009948 18 11 0,000 5,829E-03 0,01364338 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 5,829E-03 0,01363012 ! negative regulation of glucose import GO:0046325 17 11 0,000 5,829E-03 0,01361689 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 5,829E-03 0,01360368 ! embryonic gut development GO:0048566 15 11 0,000 5,829E-03 0,0135905 ! regulation of organic acid transport GO:0032890 18 11 0,000 5,829E-03 0,01357735 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 5,829E-03 0,01356421 ! cardiac cell differentiation GO:0035051 31 11 0,000 5,829E-03 0,01355111 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 5,829E-03 0,01353803 ! defense response to fungus GO:0050832 13 11 0,000 5,829E-03 0,01352497 ! developmental induction GO:0031128 19 11 0,000 5,829E-03 0,01351194 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 5,829E-03 0,01349894 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 5,829E-03 0,01348596 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 5,829E-03 0,013473 ! sequestering of metal ion GO:0051238 14 11 0,000 5,829E-03 0,01346007 ! lamellipodium assembly GO:0030032 20 11 0,000 5,829E-03 0,01344717 ! regulation of embryonic development GO:0045995 27 11 0,000 5,829E-03 0,01343429 ! nucleus localization GO:0051647 19 11 0,000 5,829E-03 0,01342143 ! regulation of synapse organization GO:0050807 17 11 0,000 5,829E-03 0,0134086 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 6,358E-03 0,01460996 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 6,358E-03 0,01459602 ! positive regulation of blood pressure GO:0045777 17 12 0,000 6,358E-03 0,0145821 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 6,358E-03 0,01456822 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 6,358E-03 0,01455435 ! virus-host interaction GO:0019048 29 12 0,000 6,358E-03 0,01454052 ! regulation of B cell proliferation GO:0030888 20 12 0,000 6,358E-03 0,01452671 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 6,358E-03 0,01451293 ! cartilage condensation GO:0001502 20 12 0,000 6,358E-03 0,01449917 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 6,358E-03 0,01448544 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 6,358E-03 0,01447174 ! protein complex disassembly GO:0043241 27 12 0,000 6,358E-03 0,01445806 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 6,358E-03 0,01444441 ! regulation of cell projection assembly GO:0060491 30 12 0,000 6,358E-03 0,01443078 ! hippocampus development GO:0021766 26 12 0,000 6,358E-03 0,01441718 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 6,358E-03 0,0144036 ! cytokine biosynthetic process GO:0042089 21 12 0,000 6,358E-03 0,01439005 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 6,358E-03 0,01437653 ! positive regulation of cell growth GO:0030307 22 12 0,000 6,358E-03 0,01436303 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 6,358E-03 0,01434956 ! regulation of exit from mitosis GO:0007096 17 12 0,000 6,358E-03 0,01433611 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 6,358E-03 0,01432268 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 6,358E-03 0,01430929 ! drug transport GO:0015893 16 12 0,000 6,358E-03 0,01429591 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 6,358E-03 0,01428256 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 6,358E-03 0,01426924 ! tyrosine metabolic process GO:0006570 16 12 0,000 6,358E-03 0,01425594 ! polyamine metabolic process GO:0006595 17 12 0,000 6,358E-03 0,01424267 ! focal adhesion formation GO:0048041 35 12 0,000 6,358E-03 0,01422942 ! mitotic spindle organization GO:0007052 21 12 0,000 6,358E-03 0,0142162 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 6,358E-03 0,014203 ! forebrain cell migration GO:0021885 21 12 0,000 6,358E-03 0,01418982 ! asymmetric protein localization GO:0008105 20 12 0,000 6,358E-03 0,01417667 ! membrane protein proteolysis GO:0033619 25 12 0,000 6,358E-03 0,01416354 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 6,358E-03 0,01415044 ! entry into host cell GO:0030260 32 12 0,000 6,358E-03 0,01413736 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 6,358E-03 0,01412431 ! monoamine transport GO:0015844 18 12 0,000 6,358E-03 0,01411128 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 6,358E-03 0,01409827 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 6,358E-03 0,01408529 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 6,358E-03 0,01407233 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 6,358E-03 0,0140594 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 6,358E-03 0,01404649 ! protein targeting to peroxisome GO:0006625 23 12 0,000 6,358E-03 0,0140336 ! protein homotetramerization GO:0051289 21 12 0,000 6,358E-03 0,01402074 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 6,358E-03 0,0140079 ! regulation of phagocytosis GO:0050764 16 12 0,000 6,358E-03 0,01399508 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 6,358E-03 0,01398229 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 6,358E-03 0,01396952 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 6,358E-03 0,01395678 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 6,358E-03 0,01394405 ! cranial nerve development GO:0021545 20 12 0,000 6,358E-03 0,01393135 ! fucose catabolic process GO:0019317 22 12 0,000 6,358E-03 0,01391868 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 6,358E-03 0,01390602 ! histone acetylation GO:0016573 26 12 0,000 6,358E-03 0,01389339 ! histone methylation GO:0016571 26 12 0,000 6,358E-03 0,01388079 ! mRNA polyadenylation GO:0006378 23 12 0,000 6,358E-03 0,0138682 ! autonomic nervous system development GO:0048483 24 12 0,000 6,358E-03 0,01385564 ! gland morphogenesis GO:0022612 29 12 0,000 6,358E-03 0,0138431 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 6,358E-03 0,01383058 ! peptidyl-lysine modification GO:0018205 21 12 0,000 6,358E-03 0,01381809 ! T cell homeostasis GO:0043029 25 12 0,000 6,358E-03 0,01380562 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 6,358E-03 0,01379317 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 6,358E-03 0,01378074 ! spleen development GO:0048536 22 12 0,000 6,358E-03 0,01376834 ! digestive tract morphogenesis GO:0048546 26 12 0,000 6,358E-03 0,01375596 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 6,358E-03 0,0137436 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 6,358E-03 0,01373126 ! regulation of RNA splicing GO:0043484 20 12 0,000 6,358E-03 0,01371895 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 6,358E-03 0,01370665 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 6,358E-03 0,01369438 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 6,358E-03 0,01368213 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 6,358E-03 0,01366991 ! response to cold GO:0009409 17 12 0,000 6,358E-03 0,0136577 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 6,358E-03 0,01364552 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 6,358E-03 0,01363336 ! cGMP metabolic process GO:0046068 18 13 0,000 6,886E-03 0,01475265 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 6,886E-03 0,01473952 ! regulation of chemokine production GO:0032642 18 13 0,000 6,886E-03 0,01472642 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 6,886E-03 0,01471334 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 6,886E-03 0,01470028 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 6,886E-03 0,01468725 ! lipid localization GO:0010876 28 13 0,000 6,886E-03 0,01467424 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 6,886E-03 0,01466126 ! organelle fusion GO:0048284 32 13 0,000 6,886E-03 0,01464829 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 6,886E-03 0,01463535 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 6,886E-03 0,01462244 ! pseudouridine synthesis GO:0001522 17 13 0,000 6,886E-03 0,01460954 ! endocrine pancreas development GO:0031018 22 13 0,000 6,886E-03 0,01459667 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 6,886E-03 0,01458382 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 6,886E-03 0,01457099 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 6,886E-03 0,01455819 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 6,886E-03 0,01454541 ! methionine metabolic process GO:0006555 27 13 0,000 6,886E-03 0,01453265 ! plasma membrane organization GO:0007009 24 13 0,000 6,886E-03 0,01451991 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 6,886E-03 0,0145072 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 6,886E-03 0,01449451 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 6,886E-03 0,01448184 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 6,886E-03 0,01446919 ! cell-cell junction assembly GO:0007043 27 13 0,000 6,886E-03 0,01445656 ! response to X-ray GO:0010165 25 13 0,000 6,886E-03 0,01444396 ! cytokine metabolic process GO:0042107 22 13 0,000 6,886E-03 0,01443138 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 6,886E-03 0,01441882 ! exocrine system development GO:0035272 32 13 0,000 6,886E-03 0,01440628 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 6,886E-03 0,01439376 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 6,886E-03 0,01438127 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 6,886E-03 0,0143688 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 6,886E-03 0,01435634 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 6,886E-03 0,01434391 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 6,886E-03 0,01433151 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 6,886E-03 0,01431912 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 6,886E-03 0,01430675 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 6,886E-03 0,01429441 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 6,886E-03 0,01428209 ! regulation of cellular pH GO:0030641 22 13 0,000 6,886E-03 0,01426979 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 6,886E-03 0,0142575 ! ribosome assembly GO:0042255 17 13 0,000 6,886E-03 0,01424525 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 6,886E-03 0,01423301 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 6,886E-03 0,01422079 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 6,886E-03 0,01420859 ! chromatin silencing GO:0006342 26 13 0,000 6,886E-03 0,01419642 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 6,886E-03 0,01418426 ! regulation of epidermis development GO:0045682 19 13 0,000 6,886E-03 0,01417213 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 6,886E-03 0,01416002 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 6,886E-03 0,01414793 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 6,886E-03 0,01413585 ! regulation of mRNA stability GO:0043488 31 13 0,000 6,886E-03 0,0141238 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 6,886E-03 0,01411177 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 6,886E-03 0,01409976 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 6,886E-03 0,01408777 ! mRNA 3'-end processing GO:0031124 24 13 0,000 6,886E-03 0,0140758 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 6,886E-03 0,01406385 ! embryonic placenta development GO:0001892 23 13 0,000 6,886E-03 0,01405193 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 6,886E-03 0,01404002 ! insulin secretion GO:0030073 23 13 0,000 6,886E-03 0,01402813 ! actin filament polymerization GO:0030041 24 13 0,000 6,886E-03 0,01401626 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 6,886E-03 0,01400441 ! acrosome reaction GO:0007340 18 13 0,000 6,886E-03 0,01399259 ! rRNA transcription GO:0009303 25 14 0,000 7,414E-03 0,01505247 ! lactation GO:0007595 26 14 0,000 7,414E-03 0,01503978 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 7,414E-03 0,01502711 ! reproductive cellular process GO:0048610 20 14 0,000 7,414E-03 0,01501446 ! tRNA modification GO:0006400 20 14 0,000 7,414E-03 0,01500184 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 7,414E-03 0,01498923 ! regulation of S phase GO:0033261 23 14 0,000 7,414E-03 0,01497664 ! water transport GO:0006833 21 14 0,000 7,414E-03 0,01496408 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 7,414E-03 0,01495154 ! non-recombinational repair GO:0000726 25 14 0,000 7,414E-03 0,01493901 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 7,414E-03 0,01492651 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 7,414E-03 0,01491403 ! retina development in camera-type eye GO:0060041 27 14 0,000 7,414E-03 0,01490157 ! hair follicle morphogenesis GO:0031069 26 14 0,000 7,414E-03 0,01488913 ! RNA polyadenylation GO:0043631 30 14 0,000 7,414E-03 0,01487672 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 7,414E-03 0,01486432 ! palate development GO:0060021 31 14 0,000 7,414E-03 0,01485194 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 7,414E-03 0,01483959 ! regulated secretory pathway GO:0045055 23 14 0,000 7,414E-03 0,01482725 ! regulation of mRNA processing GO:0050684 24 14 0,000 7,414E-03 0,01481494 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 7,414E-03 0,01480264 ! arginine metabolic process GO:0006525 17 14 0,000 7,414E-03 0,01479037 ! regulation of heart rate GO:0002027 24 14 0,000 7,414E-03 0,01477811 ! organic alcohol transport GO:0015850 29 14 0,000 7,414E-03 0,01476588 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 7,414E-03 0,01475367 ! negative regulation of caspase activity GO:0043154 22 14 0,000 7,414E-03 0,01474147 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 7,414E-03 0,0147293 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 7,414E-03 0,01471715 ! neutral amino acid transport GO:0015804 26 14 0,000 7,414E-03 0,01470501 ! L-amino acid transport GO:0015807 30 14 0,000 7,414E-03 0,0146929 ! bone mineralization GO:0030282 17 14 0,000 7,414E-03 0,01468081 ! stem cell development GO:0048864 43 14 0,000 7,414E-03 0,01466874 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 7,414E-03 0,01465668 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 7,414E-03 0,01464465 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 7,414E-03 0,01463264 ! cerebellum development GO:0021549 21 14 0,000 7,414E-03 0,01462064 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 7,414E-03 0,01460867 ! negative regulation of protein secretion GO:0050709 28 14 0,000 7,414E-03 0,01459671 ! response to gamma radiation GO:0010332 28 14 0,000 7,414E-03 0,01458478 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 7,414E-03 0,01457286 ! cofactor transport GO:0051181 26 14 0,000 7,414E-03 0,01456097 ! NADP metabolic process GO:0006739 24 14 0,000 7,414E-03 0,01454909 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 7,414E-03 0,01453723 ! protein-chromophore linkage GO:0018298 19 14 0,000 7,414E-03 0,01452539 ! intestinal absorption GO:0050892 25 14 0,000 7,414E-03 0,01451357 ! cAMP biosynthetic process GO:0006171 23 14 0,000 7,414E-03 0,01450177 ! oxygen transport GO:0015671 21 14 0,000 7,414E-03 0,01448999 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 7,414E-03 0,01447823 ! male genitalia development GO:0030539 24 14 0,000 7,414E-03 0,01446649 ! regulation of RNA stability GO:0043487 32 14 0,000 7,414E-03 0,01445477 ! regulation of axon extension GO:0030516 37 14 0,000 7,414E-03 0,01444306 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 7,414E-03 0,01443138 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 7,414E-03 0,01441971 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 7,941E-03 0,01543337 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 7,941E-03 0,01542091 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 7,941E-03 0,01540848 ! superoxide anion generation GO:0042554 20 15 0,000 7,941E-03 0,01539606 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 7,941E-03 0,01538366 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 7,941E-03 0,01537129 ! phospholipid catabolic process GO:0009395 22 15 0,000 7,941E-03 0,01535893 ! copper ion transport GO:0006825 20 15 0,000 7,941E-03 0,0153466 ! heterophilic cell adhesion GO:0007157 39 15 0,000 7,941E-03 0,01533428 ! cardiac muscle contraction GO:0060048 26 15 0,000 7,941E-03 0,01532198 ! sulfate transport GO:0008272 23 15 0,000 7,941E-03 0,0153097 ! response to cAMP GO:0051591 22 15 0,000 7,941E-03 0,01529745 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 7,941E-03 0,01528521 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 7,941E-03 0,01527299 ! ciliary or flagellar motility GO:0001539 20 15 0,000 7,941E-03 0,01526079 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 7,941E-03 0,01524861 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 7,941E-03 0,01523645 ! response to hexose stimulus GO:0009746 22 15 0,000 7,941E-03 0,01522431 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 7,941E-03 0,01521219 ! glycoprotein catabolic process GO:0006516 26 15 0,000 7,941E-03 0,01520009 ! pituitary gland development GO:0021983 29 15 0,000 7,941E-03 0,01518801 ! vesicle coating GO:0006901 33 15 0,000 7,941E-03 0,01517594 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 7,941E-03 0,0151639 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 7,941E-03 0,01515187 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 7,941E-03 0,01513987 ! regulation of exocytosis GO:0017157 22 15 0,000 7,941E-03 0,01512788 ! G1/S transition checkpoint GO:0031575 40 15 0,000 7,941E-03 0,01511591 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 7,941E-03 0,01510396 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 7,941E-03 0,01509203 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 7,941E-03 0,01508012 ! regulation of vasodilation GO:0042312 26 15 0,000 7,941E-03 0,01506823 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 7,941E-03 0,01505635 ! histone deacetylation GO:0016575 20 15 0,000 7,941E-03 0,0150445 ! mRNA splice site selection GO:0006376 38 15 0,000 7,941E-03 0,01503266 ! tissue regeneration GO:0042246 26 15 0,000 7,941E-03 0,01502084 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 7,941E-03 0,01500904 ! water homeostasis GO:0030104 27 15 0,000 7,941E-03 0,01499726 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 7,941E-03 0,0149855 ! muscle maintenance GO:0046716 26 15 0,000 7,941E-03 0,01497375 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 7,941E-03 0,01496203 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 7,941E-03 0,01495032 ! regulation of ATPase activity GO:0043462 21 15 0,000 7,941E-03 0,01493863 ! dopamine metabolic process GO:0042417 35 15 0,000 7,941E-03 0,01492696 ! heme biosynthetic process GO:0006783 29 15 0,000 7,941E-03 0,01491531 ! cell killing GO:0001906 29 15 0,000 7,941E-03 0,01490367 ! lymphocyte homeostasis GO:0002260 30 15 0,000 7,941E-03 0,01489206 ! detection of bacterium GO:0016045 18 15 0,000 7,941E-03 0,01488046 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 7,941E-03 0,01486888 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 7,941E-03 0,01485732 ! L-fucose metabolic process GO:0042354 30 15 0,000 7,941E-03 0,01484577 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 7,941E-03 0,01483425 ! peptide hormone processing GO:0016486 23 15 0,000 7,941E-03 0,01482274 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 8,468E-03 0,01579473 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 8,468E-03 0,0157825 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 8,468E-03 0,01577028 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 8,468E-03 0,01575809 ! dicarboxylic acid transport GO:0006835 38 16 0,000 8,468E-03 0,01574591 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 8,468E-03 0,01573375 ! bone remodeling GO:0046849 27 16 0,000 8,468E-03 0,01572161 ! filopodium assembly GO:0046847 32 16 0,000 8,468E-03 0,01570949 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 8,468E-03 0,01569739 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 8,468E-03 0,0156853 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 8,468E-03 0,01567324 ! positive regulation of ion transport GO:0043270 21 16 0,000 8,468E-03 0,01566119 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 8,468E-03 0,01564916 ! startle response GO:0001964 28 16 0,000 8,468E-03 0,01563715 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 8,468E-03 0,01562516 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 8,468E-03 0,01561319 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 8,468E-03 0,01560123 ! activation of MAPKK activity GO:0000186 35 16 0,000 8,468E-03 0,01558929 ! regulation of defense response to virus GO:0050688 27 16 0,000 8,468E-03 0,01557738 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 8,468E-03 0,01556548 ! protein polyubiquitination GO:0000209 34 16 0,000 8,468E-03 0,01555359 ! glutamate metabolic process GO:0006536 22 16 0,000 8,468E-03 0,01554173 ! complement activation, alternative pathway GO:0006957 18 16 0,000 8,468E-03 0,01552988 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 8,468E-03 0,01551806 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 8,468E-03 0,01550625 ! fructose metabolic process GO:0006000 25 16 0,000 8,468E-03 0,01549445 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 8,468E-03 0,01548268 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 8,468E-03 0,01547092 ! intermediate filament-based process GO:0045103 32 16 0,000 8,468E-03 0,01545919 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 8,468E-03 0,01544747 ! negative regulation of immune response GO:0050777 35 16 0,000 8,468E-03 0,01543576 ! axon cargo transport GO:0008088 43 16 0,000 8,468E-03 0,01542408 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 8,468E-03 0,01541241 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 8,468E-03 0,01540076 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 8,468E-03 0,01538913 ! DNA replication initiation GO:0006270 27 16 0,000 8,468E-03 0,01537752 ! neuron recognition GO:0008038 35 16 0,000 8,468E-03 0,01536592 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 8,468E-03 0,01535434 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 8,468E-03 0,01534278 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 8,468E-03 0,01533123 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 8,468E-03 0,0153197 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 8,468E-03 0,01530819 ! sphingolipid catabolic process GO:0030149 27 16 0,000 8,468E-03 0,0152967 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 8,468E-03 0,01528523 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 8,468E-03 0,01527377 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 8,468E-03 0,01526233 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 8,468E-03 0,0152509 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 8,468E-03 0,0152395 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 8,468E-03 0,01522811 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 8,468E-03 0,01521673 ! defense response to virus GO:0051607 37 16 0,000 8,468E-03 0,01520538 ! positive regulation of cell killing GO:0031343 32 17 0,000 8,996E-03 0,01613965 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 8,996E-03 0,01612762 ! metencephalon development GO:0022037 30 17 0,000 8,996E-03 0,01611562 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 8,996E-03 0,01610362 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 8,996E-03 0,01609165 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 8,996E-03 0,0160797 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 8,996E-03 0,01606776 ! signal complex assembly GO:0007172 41 17 0,000 8,996E-03 0,01605584 ! endothelial cell migration GO:0043542 28 17 0,000 8,996E-03 0,01604394 ! inositol metabolic process GO:0006020 28 17 0,000 8,996E-03 0,01603205 ! gene silencing by RNA GO:0031047 36 17 0,000 8,996E-03 0,01602019 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 8,996E-03 0,01600834 ! glial cell development GO:0021782 27 17 0,000 8,996E-03 0,01599651 ! limbic system development GO:0021761 36 17 0,000 8,996E-03 0,01598469 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 8,996E-03 0,01597289 ! adult walking behavior GO:0007628 33 17 0,000 8,996E-03 0,01596111 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 8,996E-03 0,01594935 ! heart looping GO:0001947 30 17 0,000 8,996E-03 0,01593761 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 8,996E-03 0,01592588 ! regulation of viral genome replication GO:0045069 28 17 0,000 8,996E-03 0,01591417 ! myoblast differentiation GO:0045445 45 17 0,000 8,996E-03 0,01590248 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 8,996E-03 0,0158908 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 8,996E-03 0,01587914 ! regulation of survival gene product expression GO:0045884 33 17 0,000 8,996E-03 0,0158675 ! cardiac muscle tissue development GO:0048738 31 17 0,000 8,996E-03 0,01585588 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 8,996E-03 0,01584427 ! glycine metabolic process GO:0006544 28 17 0,000 8,996E-03 0,01583268 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 8,996E-03 0,0158211 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 8,996E-03 0,01580955 ! NAD metabolic process GO:0019674 29 17 0,000 8,996E-03 0,01579801 ! membrane budding GO:0006900 37 17 0,000 8,996E-03 0,01578649 ! DNA integration GO:0015074 29 17 0,000 8,996E-03 0,01577498 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 8,996E-03 0,01576349 ! regulation of protein binding GO:0043393 33 17 0,000 8,996E-03 0,01575202 ! nucleobase metabolic process GO:0009112 37 17 0,000 8,996E-03 0,01574056 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 8,996E-03 0,01572912 ! DNA unwinding during replication GO:0006268 27 17 0,000 8,996E-03 0,0157177 ! genitalia development GO:0048806 30 17 0,000 8,996E-03 0,01570629 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 8,996E-03 0,0156949 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 8,996E-03 0,01568353 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 8,996E-03 0,01567217 ! neutrophil chemotaxis GO:0030593 27 17 0,000 8,996E-03 0,01566083 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 8,996E-03 0,01564951 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 8,996E-03 0,0156382 ! steroid catabolic process GO:0006706 31 17 0,000 8,996E-03 0,01562691 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 8,996E-03 0,01561564 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 8,996E-03 0,01560438 ! gas transport GO:0015669 25 17 0,000 8,996E-03 0,01559314 ! organic cation transport GO:0015695 31 17 0,000 8,996E-03 0,01558191 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 8,996E-03 0,0155707 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 8,996E-03 0,01555951 ! RNA 3'-end processing GO:0031123 34 17 0,000 8,996E-03 0,01554833 ! microspike assembly GO:0030035 36 17 0,000 8,996E-03 0,01553717 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 8,996E-03 0,01552602 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 8,996E-03 0,01551489 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 9,522E-03 0,01641168 ! neuron maturation GO:0042551 42 18 0,000 9,522E-03 0,01639993 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 9,522E-03 0,0163882 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 9,522E-03 0,01637649 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 9,522E-03 0,01636479 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 9,522E-03 0,01635311 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 9,522E-03 0,01634144 ! aminoglycan catabolic process GO:0006026 22 18 0,000 9,522E-03 0,0163298 ! memory GO:0007613 31 18 0,000 9,522E-03 0,01631816 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 9,522E-03 0,01630655 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 9,522E-03 0,01629495 ! patterning of blood vessels GO:0001569 39 18 0,000 9,522E-03 0,01628337 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 9,522E-03 0,01627181 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 9,522E-03 0,01626026 ! positive regulation of proteolysis GO:0045862 31 18 0,000 9,522E-03 0,01624873 ! epidermis morphogenesis GO:0048730 40 18 0,000 9,522E-03 0,01623721 ! glutamine metabolic process GO:0006541 29 18 0,000 9,522E-03 0,01622571 ! response to retinoic acid GO:0032526 26 18 0,000 9,522E-03 0,01621423 ! cell-substrate junction assembly GO:0007044 54 18 0,000 9,522E-03 0,01620276 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 9,522E-03 0,01619131 ! response to fungus GO:0009620 21 18 0,000 9,522E-03 0,01617988 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 9,522E-03 0,01616846 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 9,522E-03 0,01615705 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 9,522E-03 0,01614567 ! long-chain fatty acid transport GO:0015909 31 18 0,000 9,522E-03 0,0161343 ! peptide biosynthetic process GO:0043043 24 18 0,000 9,522E-03 0,01612294 ! vitamin transport GO:0051180 27 18 0,000 9,522E-03 0,01611161 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 9,522E-03 0,01610028 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 9,522E-03 0,01608898 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 9,522E-03 0,01607769 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 9,522E-03 0,01606641 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 9,522E-03 0,01605515 ! aromatic compound catabolic process GO:0019439 27 18 0,000 9,522E-03 0,01604391 ! nerve development GO:0021675 28 18 0,000 9,522E-03 0,01603268 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 9,522E-03 0,01602147 ! protein secretion GO:0009306 39 19 0,000 0,01004884 0,01689553 ! positive regulation of translation GO:0045727 30 19 0,000 0,01004884 0,01688373 ! negative regulation of defense response GO:0031348 25 19 0,000 0,01004884 0,01687195 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,01004884 0,01686018 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,01004884 0,01684843 ! skin development GO:0043588 36 19 0,000 0,01004884 0,0168367 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,01004884 0,01682499 ! lipid phosphorylation GO:0046834 35 19 0,000 0,01004884 0,01681329 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,01004884 0,0168016 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,01004884 0,01678993 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,01004884 0,01677828 ! bile acid metabolic process GO:0008206 29 19 0,000 0,01004884 0,01676665 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,01004884 0,01675503 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,01004884 0,01674342 ! cerebral cortex development GO:0021987 36 19 0,000 0,01004884 0,01673184 ! pigmentation during development GO:0048066 41 19 0,000 0,01004884 0,01672027 ! response to vitamin A GO:0033189 27 19 0,000 0,01004884 0,01670871 ! heme metabolic process GO:0042168 36 19 0,000 0,01004884 0,01669717 ! actin filament bundle formation GO:0051017 42 19 0,000 0,01004884 0,01668565 ! neuromuscular junction development GO:0007528 34 19 0,000 0,01004884 0,01667414 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,01004884 0,01666265 ! plasma membrane fusion GO:0045026 28 19 0,000 0,01004884 0,01665117 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,01004884 0,01663971 ! peptide cross-linking GO:0018149 37 19 0,000 0,01004884 0,01662827 ! protein export from nucleus GO:0006611 36 19 0,000 0,01004884 0,01661684 ! heart process GO:0003015 30 19 0,000 0,01004884 0,01660543 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,01004884 0,01659403 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,01004884 0,01658265 ! visual learning GO:0008542 36 19 0,000 0,01004884 0,01657128 ! cellular pigmentation GO:0033059 36 19 0,000 0,01004884 0,01655993 ! G1 phase GO:0051318 40 19 0,000 0,01004884 0,0165486 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,01004884 0,01653728 ! cell-cell junction organization GO:0045216 35 19 0,000 0,01004884 0,01652598 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,01004884 0,01651469 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,01004884 0,01650342 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,01004884 0,01649216 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,01004884 0,01648092 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,01004884 0,01646969 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,01004884 0,01645848 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,01004884 0,01644728 ! cilium assembly GO:0042384 37 19 0,000 0,01004884 0,0164361 ! peptide hormone secretion GO:0030072 31 19 0,000 0,01004884 0,01642493 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,01057509 0,01727337 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,01057509 0,01726165 ! positive regulation of ossification GO:0045778 47 20 0,000 0,01057509 0,01724995 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,01057509 0,01723826 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,01057509 0,01722659 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,01057509 0,01721493 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,01057509 0,0172033 ! cAMP metabolic process GO:0046058 36 20 0,000 0,01057509 0,01719167 ! response to vitamin GO:0033273 31 20 0,000 0,01057509 0,01718006 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,01057509 0,01716847 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,01057509 0,01715689 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,01057509 0,01714533 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,01057509 0,01713379 ! response to alkaloid GO:0043279 38 20 0,000 0,01057509 0,01712226 ! retinoid metabolic process GO:0001523 32 20 0,000 0,01057509 0,01711074 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,01057509 0,01709924 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,01057509 0,01708776 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,01057509 0,01707629 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,01057509 0,01706484 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,01057509 0,0170534 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,01057509 0,01704198 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,01057509 0,01703057 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,01057509 0,01701918 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,01057509 0,0170078 ! body fluid secretion GO:0007589 31 20 0,000 0,01057509 0,01699644 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,01057509 0,0169851 ! peptide secretion GO:0002790 35 20 0,000 0,01057509 0,01697376 ! stem cell differentiation GO:0048863 53 20 0,000 0,01057509 0,01696245 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,01057509 0,01695115 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,01057509 0,01693986 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,01057509 0,01692859 ! sensory perception of pain GO:0019233 30 20 0,000 0,01057509 0,01691734 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,01057509 0,0169061 ! diencephalon development GO:0021536 34 20 0,000 0,01057509 0,01689487 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,01057509 0,01688366 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,01057509 0,01687246 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,01057509 0,01686128 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,01057509 0,01685011 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,01057509 0,01683896 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,01057509 0,01682783 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,01057509 0,0168167 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,01057509 0,0168056 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,01057509 0,0167945 ! regulation of glucose import GO:0046324 29 20 0,000 0,01057509 0,01678343 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,01057509 0,01677236 ! actin filament-based movement GO:0030048 43 20 0,000 0,01057509 0,01676131 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,01057509 0,01675028 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,01057509 0,01673926 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,01057509 0,01672825 ! negative regulation of translation GO:0017148 29 20 0,000 0,01057509 0,01671726 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,01057509 0,01670629 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,01057509 0,01669532 ! regulation of cell killing GO:0031341 42 21 0,000 0,01110109 0,01751424 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,01110109 0,01750276 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,01110109 0,0174913 ! hormone secretion GO:0046879 38 21 0,000 0,01110109 0,01747985 ! glycerol metabolic process GO:0006071 34 21 0,000 0,01110109 0,01746842 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,01110109 0,017457 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,01110109 0,0174456 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,01110109 0,01743421 ! axis specification GO:0009798 38 21 0,000 0,01110109 0,01742284 ! ovarian follicle development GO:0001541 35 21 0,000 0,01110109 0,01741148 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,01110109 0,01740014 ! smooth muscle contraction GO:0006939 46 21 0,000 0,01110109 0,01738881 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,01110109 0,0173775 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,01110109 0,0173662 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,01110109 0,01735491 ! cell aging GO:0007569 44 21 0,000 0,01110109 0,01734364 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,01110109 0,01733239 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,01110109 0,01732115 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,01110109 0,01730992 ! cytolysis GO:0019835 24 21 0,000 0,01110109 0,01729871 ! vasodilation GO:0042311 39 21 0,000 0,01110109 0,01728752 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,01110109 0,01727633 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,01110109 0,01726517 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,01110109 0,01725401 ! oogenesis GO:0048477 36 21 0,000 0,01110109 0,01724287 ! DNA modification GO:0006304 34 21 0,000 0,01110109 0,01723175 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,01110109 0,01722064 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,01110109 0,01720954 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,01110109 0,01719846 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,01110109 0,01718739 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,01110109 0,01717634 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,01110109 0,0171653 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,01110109 0,01715428 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,01110109 0,01714327 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,01110109 0,01713227 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,01110109 0,01712129 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,01110109 0,01711032 ! collagen catabolic process GO:0030574 28 21 0,000 0,01110109 0,01709937 ! sperm-egg recognition GO:0035036 21 21 0,000 0,01110109 0,01708843 ! gut development GO:0048565 39 21 0,000 0,01110109 0,0170775 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,01162682 0,01787484 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,01162682 0,01786342 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,01162682 0,01785202 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,01162682 0,01784064 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,01162682 0,01782927 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,01162682 0,01781791 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,01162682 0,01780657 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,01162682 0,01779524 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,01162682 0,01778393 ! regeneration GO:0031099 41 22 0,000 0,01162682 0,01777263 ! keratinization GO:0031424 28 22 0,000 0,01162682 0,01776135 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,01162682 0,01775008 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,01162682 0,01773882 ! sensory perception of taste GO:0050909 28 22 0,000 0,01162682 0,01772758 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,01162682 0,01771635 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,01162682 0,01770514 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,01162682 0,01769394 ! vacuolar transport GO:0007034 36 22 0,000 0,01162682 0,01768276 ! lysosome organization GO:0007040 41 22 0,000 0,01162682 0,01767158 ! central nervous system neuron development GO:0021954 46 22 0,000 0,01162682 0,01766043 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,01162682 0,01764929 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,01162682 0,01763816 ! fucose metabolic process GO:0006004 39 22 0,000 0,01162682 0,01762704 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,01162682 0,01761594 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,01162682 0,01760486 ! ureteric bud development GO:0001657 43 22 0,000 0,01162682 0,01759379 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,01162682 0,01758273 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,01162682 0,01757168 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,01162682 0,01756065 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,01162682 0,01754964 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,01162682 0,01753863 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,01162682 0,01752764 ! sarcomere organization GO:0045214 30 22 0,000 0,01162682 0,01751667 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,01162682 0,01750571 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,01162682 0,01749476 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,01162682 0,01748382 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,01162682 0,0174729 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,01162682 0,017462 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,01162682 0,0174511 ! protein stabilization GO:0050821 39 22 0,000 0,01162682 0,01744022 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,01215228 0,01821707 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,01215228 0,01820573 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,01215228 0,0181944 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,01215228 0,01818308 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,01215228 0,01817178 ! gluconeogenesis GO:0006094 33 23 0,000 0,01215228 0,01816049 ! viral genome replication GO:0019079 41 23 0,000 0,01215228 0,01814922 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,01215228 0,01813796 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,01215228 0,01812672 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,01215228 0,01811549 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,01215228 0,01810427 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,01215228 0,01809307 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,01215228 0,01808188 ! visual behavior GO:0007632 42 23 0,000 0,01215228 0,0180707 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,01215228 0,01805954 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,01215228 0,01804839 ! response to ethanol GO:0045471 46 23 0,000 0,01215228 0,01803726 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,01215228 0,01802614 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,01215228 0,01801503 ! peroxisome organization GO:0007031 37 23 0,000 0,01215228 0,01800394 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,01215228 0,01799286 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,01215228 0,01798179 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,01215228 0,01797074 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,01215228 0,0179597 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,01215228 0,01794868 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,01215228 0,01793767 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,01215228 0,01792667 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,01215228 0,01791568 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,01215228 0,01790471 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,01215228 0,01789376 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,01215228 0,01788281 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,01215228 0,01787188 ! fatty acid transport GO:0015908 44 23 0,000 0,01215228 0,01786096 ! platelet activation GO:0030168 37 23 0,000 0,01215228 0,01785006 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,01215228 0,01783917 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,01215228 0,01782829 ! hormone transport GO:0009914 40 23 0,000 0,01215228 0,01781743 ! cell-cell recognition GO:0009988 25 23 0,000 0,01215228 0,01780657 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,01215228 0,01779574 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,01215228 0,01778491 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,01215228 0,0177741 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,01215228 0,0177633 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,01215228 0,01775252 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,01267749 0,01850852 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,01267749 0,0184973 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,01267749 0,01848609 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,01267749 0,01847489 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,01267749 0,01846371 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,01267749 0,01845254 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,01267749 0,01844138 ! vesicle docking GO:0048278 47 24 0,000 0,01267749 0,01843024 ! spinal cord development GO:0021510 47 24 0,000 0,01267749 0,01841911 ! vacuole organization GO:0007033 43 24 0,000 0,01267749 0,01840799 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,01267749 0,01839689 ! digestive system process GO:0022600 39 24 0,000 0,01267749 0,0183858 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,01267749 0,01837472 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,01267749 0,01836366 ! regulation of behavior GO:0050795 43 24 0,000 0,01267749 0,01835261 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,01267749 0,01834158 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,01267749 0,01833055 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,01267749 0,01831955 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,01267749 0,01830855 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,01267749 0,01829757 ! membrane depolarization GO:0051899 39 24 0,000 0,01267749 0,0182866 ! pallium development GO:0021543 49 24 0,000 0,01267749 0,01827564 ! pentose metabolic process GO:0019321 35 24 0,000 0,01267749 0,0182647 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,01267749 0,01825377 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,01267749 0,01824285 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,01267749 0,01823194 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,01267749 0,01822105 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,01267749 0,01821017 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,01267749 0,01819931 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,01267749 0,01818846 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,01267749 0,01817762 ! regulation of amine transport GO:0051952 40 24 0,000 0,01267749 0,01816679 ! protein tetramerization GO:0051262 52 24 0,000 0,01267749 0,01815598 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,01320244 0,01889653 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,01320244 0,01888529 ! myelination GO:0042552 45 25 0,000 0,01320244 0,01887407 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,01320244 0,01886286 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,01320244 0,01885167 ! phototransduction GO:0007602 33 25 0,000 0,01320244 0,01884049 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,01320244 0,01882932 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,01320244 0,01881816 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,01320244 0,01880702 ! sperm motility GO:0030317 31 25 0,000 0,01320244 0,01879589 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,01320244 0,01878478 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,01320244 0,01877368 ! receptor metabolic process GO:0043112 46 25 0,000 0,01320244 0,01876259 ! chromosome condensation GO:0030261 45 25 0,000 0,01320244 0,01875151 ! response to starvation GO:0042594 42 25 0,000 0,01320244 0,01874045 ! osteoblast differentiation GO:0001649 60 25 0,000 0,01320244 0,0187294 ! neural crest cell development GO:0014032 54 25 0,000 0,01320244 0,01871836 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,01320244 0,01870734 ! negative regulation of cell development GO:0010721 73 25 0,000 0,01320244 0,01869633 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,01320244 0,01868533 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,01320244 0,01867434 ! interaction with host GO:0051701 62 25 0,000 0,01320244 0,01866337 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,01320244 0,01865241 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,01320244 0,01864147 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,01320244 0,01863053 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,01320244 0,01861961 ! immunoglobulin production GO:0002377 55 25 0,000 0,01320244 0,0186087 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,01320244 0,01859781 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,01320244 0,01858693 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,01320244 0,01857606 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,01320244 0,0185652 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,01320244 0,01855436 ! telomere organization GO:0032200 43 25 0,000 0,01320244 0,01854353 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,01320244 0,01853271 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,01320244 0,0185219 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,01372712 0,01924676 ! embryonic pattern specification GO:0009880 44 26 0,000 0,01372712 0,01923555 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,01372712 0,01922436 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,01372712 0,01921317 ! initiation of viral infection GO:0019059 57 26 0,000 0,01372712 0,019202 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,01372712 0,01919085 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,01372712 0,0191797 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,01372712 0,01916857 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,01372712 0,01915745 ! molting cycle process GO:0022404 50 26 0,000 0,01372712 0,01914635 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,01372712 0,01913525 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,01372712 0,01912417 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,01372712 0,01911311 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,01372712 0,01910205 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,01372712 0,01909101 GO:0051297|centrosome organization, ! insulin receptor signaling pathway GO:0008286 64 26 0,000 0,01372712 0,01907998 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,01372712 0,01906896 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,01372712 0,01905796 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,01372712 0,01904697 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,01372712 0,01903599 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,01372712 0,01902503 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,01372712 0,01901407 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,01372712 0,01900313 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,01372712 0,01899221 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,01372712 0,01898129 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,01372712 0,01897039 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,01372712 0,0189595 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,01372712 0,01894862 ! blastocyst development GO:0001824 49 26 0,000 0,01372712 0,01893776 ! leukocyte proliferation GO:0070661 52 26 0,000 0,01372712 0,0189269 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,01372712 0,01891606 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,01372712 0,01890524 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,01425154 0,01961625 ! neuron fate commitment GO:0048663 48 27 0,000 0,01425154 0,01960503 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,01425154 0,01959383 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,01425154 0,01958264 ! iron ion transport GO:0006826 59 27 0,000 0,01425154 0,01957146 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,01425154 0,0195603 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,01425154 0,01954915 ! protein amino acid acylation GO:0043543 55 27 0,000 0,01425154 0,01953801 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,01425154 0,01952688 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,01425154 0,01951577 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,01425154 0,01950467 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,01425154 0,01949358 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,01425154 0,0194825 ! autophagy GO:0006914 41 27 0,000 0,01425154 0,01947144 ! male gonad development GO:0008584 44 27 0,000 0,01425154 0,01946039 ! response to toxin GO:0009636 47 27 0,000 0,01425154 0,01944935 ! primary neural tube formation GO:0014020 51 27 0,000 0,01425154 0,01943832 ! base-excision repair GO:0006284 41 27 0,000 0,01425154 0,01942731 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,01425154 0,01941631 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,01425154 0,01940532 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,01425154 0,01939435 ! glutathione metabolic process GO:0006749 39 27 0,000 0,01425154 0,01938338 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,01425154 0,01937243 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,01425154 0,01936149 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,01425154 0,01935057 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,01425154 0,01933965 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,0147757 0,02003965 ! circadian rhythm GO:0007623 50 28 0,000 0,0147757 0,02002836 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,0147757 0,02001708 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,0147757 0,02000582 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,0147757 0,01999456 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,0147757 0,01998332 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,0147757 0,0199721 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,0147757 0,01996088 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,0147757 0,01994968 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,0147757 0,01993849 ! synaptogenesis GO:0007416 42 28 0,000 0,0147757 0,01992732 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,0147757 0,01991615 ! lipid oxidation GO:0034440 43 28 0,000 0,0147757 0,019905 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,0147757 0,01989386 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,0147757 0,01988274 ! translational initiation GO:0006413 65 29 0,000 0,0152996 0,02057621 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,0152996 0,02056471 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,0152996 0,02055323 ! regulation of pH GO:0006885 43 29 0,000 0,0152996 0,02054176 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,0152996 0,0205303 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,0152996 0,02051886 ! catechol metabolic process GO:0009712 54 29 0,000 0,0152996 0,02050743 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,0152996 0,02049601 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,0152996 0,0204846 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,0152996 0,02047321 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,0152996 0,02046183 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,0152996 0,02045046 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,0152996 0,02043911 ! cell fate determination GO:0001709 60 29 0,000 0,0152996 0,02042777 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,0152996 0,02041644 ! detection of light stimulus GO:0009583 38 29 0,000 0,0152996 0,02040512 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 0,0152996 0,02039381 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,0152996 0,02038252 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,0152996 0,02037124 ! tissue homeostasis GO:0001894 48 29 0,000 0,0152996 0,02035997 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,0152996 0,02034872 ! phenol metabolic process GO:0018958 55 30 0,000 0,01582324 0,02103354 ! zinc ion transport GO:0006829 45 30 0,000 0,01582324 0,02102192 ! membrane docking GO:0022406 61 30 0,000 0,01582324 0,02101032 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,01582324 0,02099873 ! cell junction assembly GO:0034329 78 30 0,000 0,01582324 0,02098716 ! regulation of innate immune response GO:0045088 51 30 0,000 0,01582324 0,0209756 ! acute-phase response GO:0006953 49 30 0,000 0,01582324 0,02096405 ! myofibril assembly GO:0030239 47 30 0,000 0,01582324 0,02095251 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,01582324 0,02094098 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,01582324 0,02092947 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,01582324 0,02091797 ! phospholipid transport GO:0015914 51 30 0,000 0,01582324 0,02090648 ! ensheathment of neurons GO:0007272 57 30 0,000 0,01582324 0,02089501 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,01582324 0,02088355 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,01582324 0,0208721 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,01582324 0,02086066 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,01582324 0,02084924 ! eye morphogenesis GO:0048592 60 30 0,000 0,01582324 0,02083782 ! regulation of B cell activation GO:0050864 50 30 0,000 0,01582324 0,02082643 ! response to heat GO:0009408 50 30 0,000 0,01582324 0,02081504 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,01634661 0,02149178 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,01634661 0,02148004 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,01634661 0,02146831 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,01634661 0,0214566 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,01634661 0,0214449 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,01634661 0,02143322 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,01634661 0,02142154 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,01634661 0,02140988 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,01634661 0,02139823 ! ovulation cycle process GO:0022602 49 31 0,000 0,01634661 0,0213866 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,01634661 0,02137497 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,01634661 0,02136336 ! peptide transport GO:0015833 55 31 0,000 0,01634661 0,02135176 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,01634661 0,02134018 ! iron ion homeostasis GO:0055072 54 31 0,000 0,01634661 0,02132861 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,01634661 0,02131705 ! mesoderm formation GO:0001707 69 31 0,000 0,01634661 0,0213055 ! natural killer cell activation GO:0030101 45 31 0,000 0,01634661 0,02129396 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,01634661 0,02128244 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,01634661 0,02127093 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,01634661 0,02125943 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,01634661 0,02124795 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,01634661 0,02123647 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,01686973 0,02190424 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,01686973 0,02189243 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,01686973 0,02188063 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,01686973 0,02186884 ! cholesterol transport GO:0030301 56 32 0,000 0,01686973 0,02185706 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,01686973 0,0218453 ! spliceosome assembly GO:0000245 67 32 0,000 0,01686973 0,02183355 ! spindle organization GO:0007051 46 32 0,000 0,01686973 0,02182181 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,01686973 0,02181008 ! metanephros development GO:0001656 74 32 0,000 0,01686973 0,02179837 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,01686973 0,02178667 ! response to ionizing radiation GO:0010212 65 32 0,000 0,01686973 0,02177498 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,01686973 0,02176331 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,01686973 0,02175164 ! muscle cell development GO:0055001 49 32 0,000 0,01686973 0,02173999 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,01686973 0,02172835 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,01686973 0,02171673 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,01686973 0,02170512 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,01686973 0,02169351 ! ovulation cycle GO:0042698 51 32 0,000 0,01686973 0,02168193 ! peripheral nervous system development GO:0007422 64 32 0,000 0,01686973 0,02167035 ! BMP signaling pathway GO:0030509 64 32 0,000 0,01686973 0,02165879 ! hindbrain development GO:0030902 61 32 0,000 0,01686973 0,02164724 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,01686973 0,0216357 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,01686973 0,02162417 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,01686973 0,02161265 ! gene silencing GO:0016458 65 32 0,000 0,01686973 0,02160115 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,01739258 0,02225881 ! post-embryonic development GO:0009791 69 33 0,000 0,01739258 0,02224697 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,01739258 0,02223515 ! protein targeting to membrane GO:0006612 68 33 0,000 0,01739258 0,02222334 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,01739258 0,02221155 ! ceramide metabolic process GO:0006672 64 33 0,000 0,01739258 0,02219976 ! formation of primary germ layer GO:0001704 72 33 0,000 0,01739258 0,02218799 ! cell fate specification GO:0001708 52 33 0,000 0,01739258 0,02217623 ! sterol transport GO:0015918 57 33 0,000 0,01739258 0,02216449 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,01739258 0,02215276 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,01739258 0,02214103 ! adult locomotory behavior GO:0008344 59 33 0,000 0,01739258 0,02212933 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,01739258 0,02211763 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,01739258 0,02210595 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,01791518 0,02275814 ! glial cell differentiation GO:0010001 63 34 0,000 0,01791518 0,02274613 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,01791518 0,02273413 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,01791518 0,02272215 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,01791518 0,02271018 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,01791518 0,02269822 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,01791518 0,02268627 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,01791518 0,02267434 ! mismatch repair GO:0006298 46 34 0,000 0,01791518 0,02266242 ! spermatid development GO:0007286 63 34 0,000 0,01791518 0,02265051 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,01791518 0,02263861 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,01791518 0,02262673 ! placenta development GO:0001890 53 34 0,000 0,01791518 0,02261486 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,01791518 0,022603 ! regulation of muscle development GO:0048634 70 35 0,000 0,01843751 0,02324982 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,01843751 0,02323764 ! negative regulation of secretion GO:0051048 63 35 0,000 0,01843751 0,02322547 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,01843751 0,02321332 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,01843751 0,02320118 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,01843751 0,02318905 ! odontogenesis GO:0042476 66 35 0,000 0,01843751 0,02317693 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,01843751 0,02316483 ! female gonad development GO:0008585 58 35 0,000 0,01843751 0,02315274 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,01843751 0,02314066 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,01843751 0,0231286 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,01843751 0,02311654 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,01843751 0,02310451 ! cytokine production GO:0001816 59 35 0,000 0,01843751 0,02309248 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,01843751 0,02308046 ! neural tube formation GO:0001841 67 35 0,000 0,01843751 0,02306846 ! vesicle localization GO:0051648 64 35 0,000 0,01843751 0,02305647 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,01895958 0,02369702 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,01895958 0,02368471 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,01895958 0,02367242 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,01895958 0,02366014 ! cell junction organization GO:0034330 86 36 0,000 0,01895958 0,02364788 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,01895958 0,02363563 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,01895958 0,02362339 ! positive regulation of cell development GO:0010720 80 36 0,000 0,01895958 0,02361116 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,01895958 0,02359894 ! regulation of proteolysis GO:0030162 72 36 0,000 0,01895958 0,02358674 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,01895958 0,02357455 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,01895958 0,02356237 ! aerobic respiration GO:0009060 55 36 0,000 0,01895958 0,02355021 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,01895958 0,02353806 ! embryonic organ development GO:0048568 57 36 0,000 0,01895958 0,02352592 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,01895958 0,02351379 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,01895958 0,02350168 ! RNA export from nucleus GO:0006405 56 37 0,000 0,0194814 0,02413607 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,0194814 0,02412364 ! meiosis I GO:0007127 65 37 0,000 0,0194814 0,02411123 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,0194814 0,02409884 ! sister chromatid segregation GO:0000819 58 37 0,000 0,0194814 0,02408645 ! actomyosin structure organization GO:0031032 62 37 0,000 0,0194814 0,02407408 ! organic anion transport GO:0015711 68 37 0,000 0,0194814 0,02406172 ! tissue remodeling GO:0048771 76 37 0,000 0,0194814 0,02404938 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,0194814 0,02403705 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,0194814 0,02402473 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,0194814 0,02401242 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,0194814 0,02400012 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,0194814 0,02398784 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,0194814 0,02397557 ! glycogen metabolic process GO:0005977 61 37 0,000 0,0194814 0,02396331 ! pigment metabolic process GO:0042440 80 37 0,000 0,0194814 0,02395107 ! spermatid differentiation GO:0048515 66 37 0,000 0,0194814 0,02393883 ! cellular response to insulin stimulus GO:0032869 82 37 0,000 0,0194814 0,02392661 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,02000295 0,02455464 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,02000295 0,02454212 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,02000295 0,02452961 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,02000295 0,02451711 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,02000295 0,02450463 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,02000295 0,02449216 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,02000295 0,0244797 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,02000295 0,02446726 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,02000295 0,02445482 ! lipid homeostasis GO:0055088 67 38 0,000 0,02000295 0,0244424 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,02000295 0,02443 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,02000295 0,0244176 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,02000295 0,02440522 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,02000295 0,02439285 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,02000295 0,02438049 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,02000295 0,02436815 ! glucan metabolic process GO:0044042 62 38 0,000 0,02000295 0,02435582 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,02052424 0,02497791 ! mammary gland development GO:0030879 86 39 0,000 0,02052424 0,02496528 ! learning GO:0007612 77 39 0,000 0,02052424 0,02495266 ! ear morphogenesis GO:0042471 60 39 0,000 0,02052424 0,02494006 ! organic ether metabolic process GO:0018904 55 39 0,000 0,02052424 0,02492747 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,02052424 0,0249149 ! segmentation GO:0035282 67 39 0,000 0,02052424 0,02490233 ! ion transmembrane transport GO:0034220 66 39 0,000 0,02052424 0,02488978 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,02052424 0,02487724 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,02052424 0,02486471 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,02052424 0,0248522 ! RNA modification GO:0009451 57 39 0,000 0,02052424 0,0248397 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,02052424 0,02482721 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,02104527 0,02544469 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,02104527 0,02543191 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,02104527 0,02541914 ! feeding behavior GO:0007631 59 40 0,000 0,02104527 0,02540639 ! negative regulation of binding GO:0051100 72 40 0,000 0,02104527 0,02539364 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,02104527 0,02538092 ! mesenchymal cell development GO:0014031 87 40 0,000 0,02104527 0,0253682 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,02104527 0,0253555 ! maintenance of protein location GO:0045185 91 40 0,000 0,02104527 0,02534281 ! cytokinesis GO:0000910 72 40 0,000 0,02104527 0,02533013 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,02156605 0,02594395 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,02156605 0,02593099 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,02156605 0,02591803 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,02156605 0,0259051 ! gliogenesis GO:0042063 88 41 0,000 0,02156605 0,02589217 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,02156605 0,02587925 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,02156605 0,02586635 ! T cell differentiation GO:0030217 81 41 0,000 0,02156605 0,02585347 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,02156605 0,02584059 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,02156605 0,02582773 ! female gamete generation GO:0007292 61 41 0,000 0,02156605 0,02581488 ! polyol metabolic process GO:0019751 66 41 0,000 0,02156605 0,02580204 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,02156605 0,02578922 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,02208656 0,02639854 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,02208656 0,02638543 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,02208656 0,02637234 ! regulation of tube size GO:0035150 71 42 0,000 0,02208656 0,02635926 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,02208656 0,02634619 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,02208656 0,02633313 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,02208656 0,02632009 ! regulation of intracellular protein transport GO:0033157 80 42 0,000 0,02208656 0,02630706 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,02208656 0,02629404 ! neuron migration GO:0001764 79 42 0,000 0,02208656 0,02628104 ! regulation of protein secretion GO:0050708 71 42 0,000 0,02208656 0,02626805 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,02208656 0,02625507 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,02260681 0,02686024 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,02260681 0,02684698 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,02260681 0,02683374 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,02260681 0,02682051 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,02260681 0,02680729 ! glucose transport GO:0015758 65 43 0,000 0,02260681 0,02679408 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,02260681 0,02678089 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,02260681 0,02676771 ! neural tube development GO:0021915 77 43 0,000 0,02260681 0,02675454 ! regulation of epithelial cell proliferation GO:0050678 111 43 0,000 0,02260681 0,02674139 ! striated muscle contraction GO:0006941 77 43 0,000 0,02260681 0,02672825 ! phagocytosis GO:0006909 90 43 0,000 0,02260681 0,02671512 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,02260681 0,02670201 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,02312681 0,02730279 ! hexose transport GO:0008645 67 44 0,000 0,02312681 0,0272894 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,02312681 0,02727603 ! male sex differentiation GO:0046661 76 44 0,000 0,02312681 0,02726266 ! double-strand break repair GO:0006302 81 44 0,000 0,02312681 0,02724931 ! biopolymer methylation GO:0043414 84 44 0,000 0,02312681 0,02723597 ! B cell differentiation GO:0030183 107 44 0,000 0,02312681 0,02722265 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,02312681 0,02720934 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,02312681 0,02719604 ! developmental growth GO:0048589 82 44 0,000 0,02312681 0,02718275 ! maintenance of location in cell GO:0051651 97 44 0,000 0,02312681 0,02716948 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,02364654 0,02776651 ! glycolysis GO:0006096 65 45 0,000 0,02364654 0,02775296 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,02364654 0,02773943 ! leukocyte migration GO:0050900 68 45 0,000 0,02364654 0,02772591 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,02364654 0,02771241 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,02364654 0,02769892 ! induction of apoptosis by intracellular signals GO:0008629 93 45 0,000 0,02364654 0,02768544 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,02364654 0,02767197 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,02364654 0,02765852 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,02364654 0,02764508 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,02364654 0,02763165 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,02364654 0,02761824 ! cell growth GO:0016049 84 45 0,000 0,02364654 0,02760484 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,02416601 0,02819759 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 0,000 0,02416601 0,02818392 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,02416601 0,02817027 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,02416601 0,02815663 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,02416601 0,028143 ! pigmentation GO:0043473 100 46 0,000 0,02416601 0,02812938 ! response to insulin stimulus GO:0032868 95 46 0,000 0,02416601 0,02811578 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,02416601 0,02810219 ! positive regulation of defense response GO:0031349 76 47 0,000 0,02468523 0,02869211 ! endosome transport GO:0016197 108 47 0,000 0,02468523 0,02867825 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,02468523 0,02866441 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,02468523 0,02865059 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,02468523 0,02863677 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,02468523 0,02862297 ! JNK cascade GO:0007254 91 47 0,000 0,02468523 0,02860918 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,02468523 0,02859541 ! methylation GO:0032259 90 47 0,000 0,02468523 0,02858165 ! protein homooligomerization GO:0051260 76 47 0,000 0,02468523 0,0285679 ! mitochondrial transport GO:0006839 82 48 0,000 0,02520419 0,02915446 ! Notch signaling pathway GO:0007219 96 48 0,000 0,02520419 0,02914045 ! cellular component disassembly GO:0022411 86 48 0,000 0,02520419 0,02912645 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,02520419 0,02911247 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,02520419 0,0290985 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,02520419 0,02908454 ! activation of caspase activity GO:0006919 84 48 0,000 0,02520419 0,0290706 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,02520419 0,02905667 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,02520419 0,02904276 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,02520419 0,02902885 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,02520419 0,02901496 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,02572289 0,02959793 ! regulation of action potential GO:0001508 95 49 0,000 0,02572289 0,02958378 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,02572289 0,02956964 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,02572289 0,02955552 ! regulation of ion transport GO:0043269 77 49 0,000 0,02572289 0,02954141 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,02572289 0,02952732 ! peptide metabolic process GO:0006518 76 49 0,000 0,02572289 0,02951324 ! response to temperature stimulus GO:0009266 76 49 0,000 0,02572289 0,02949917 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,02572289 0,02948512 ! endocrine system development GO:0035270 104 49 0,000 0,02572289 0,02947108 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,02572289 0,02945705 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,02572289 0,02944304 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,02572289 0,02942904 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,02572289 0,02941505 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,02624133 0,02999365 ! neuromuscular process GO:0050905 99 50 0,000 0,02624133 0,02997941 ! regulation of ossification GO:0030278 117 50 0,000 0,02624133 0,02996518 ! inner ear development GO:0048839 79 50 0,000 0,02624133 0,02995096 ! histone modification GO:0016570 91 50 0,000 0,02624133 0,02993676 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,02624133 0,02992257 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,02624133 0,0299084 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,02624133 0,02989424 ! positive regulation of binding GO:0051099 78 51 0,000 0,02675951 0,03047012 ! viral infectious cycle GO:0019058 99 51 0,000 0,02675951 0,03045571 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,02675951 0,03044131 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,02675951 0,03042692 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,02675951 0,03041255 ! excretion GO:0007588 83 51 0,000 0,02675951 0,03039819 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,02675951 0,03038385 ! chromatin remodeling GO:0006338 109 51 0,000 0,02675951 0,03036951 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,02675951 0,0303552 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,02675951 0,03034089 ! vesicle organization GO:0016050 107 51 0,000 0,02675951 0,0303266 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,02675951 0,03031232 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 0,000 0,02675951 0,03029806 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,02675951 0,03028381 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,02727743 0,03085543 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,02727743 0,03084093 ! membrane fusion GO:0006944 110 52 0,000 0,02727743 0,03082644 ! positive regulation of growth GO:0045927 90 52 0,000 0,02727743 0,03081197 ! covalent chromatin modification GO:0016569 101 52 0,000 0,02727743 0,03079751 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,02727743 0,03078306 ! amino acid activation GO:0043038 92 52 0,000 0,02727743 0,03076863 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,02727743 0,03075421 ! synapse organization GO:0050808 85 52 0,000 0,02727743 0,03073981 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,02779509 0,03130852 ! RNA catabolic process GO:0006401 93 53 0,000 0,02779509 0,03129387 ! regulation of translational initiation GO:0006446 82 53 0,000 0,02779509 0,03127923 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,02779509 0,03126461 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,02779509 0,03125 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,02779509 0,0312354 ! cell maturation GO:0048469 100 53 0,000 0,02779509 0,03122082 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,02779509 0,03120625 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,02779509 0,03119169 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,0283125 0,03175751 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,0283125 0,03174272 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,0283125 0,03172793 ! cell recognition GO:0008037 85 54 0,000 0,0283125 0,03171316 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,0283125 0,0316984 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,0283125 0,03168366 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,0283125 0,03166893 ! chloride transport GO:0006821 90 55 0,000 0,02882964 0,0322324 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,02882964 0,03221743 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,02882964 0,03220247 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,02882964 0,03218753 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,02882964 0,0321726 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,02882964 0,03215768 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,02882964 0,03214278 ! aging GO:0007568 103 55 0,000 0,02882964 0,03212789 ! gastrulation GO:0007369 112 55 0,000 0,02882964 0,03211302 ! heart morphogenesis GO:0003007 97 55 0,000 0,02882964 0,03209816 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,02882964 0,03208331 ! RNA elongation GO:0006354 79 55 0,000 0,02882964 0,03206848 ! nuclear export GO:0051168 97 55 0,000 0,02882964 0,03205366 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,02882964 0,03203886 ! regulation of actin filament length GO:0030832 105 56 0,000 0,02934653 0,03259823 ! sensory perception of smell GO:0007608 80 56 0,000 0,02934653 0,03258318 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,02934653 0,03256816 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,02934653 0,03255314 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,02934653 0,03253814 ! regulation of DNA replication GO:0006275 101 56 0,000 0,02934653 0,03252315 ! proton transport GO:0015992 94 56 0,000 0,02934653 0,03250818 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,02934653 0,03249322 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,02986317 0,03305003 ! muscle fiber development GO:0048747 112 57 0,000 0,02986317 0,03303484 ! positive regulation of cell migration GO:0030335 126 57 0,000 0,02986317 0,03301966 ! lipid modification GO:0030258 97 57 0,000 0,02986317 0,03300449 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,02986317 0,03298934 ! regulation of intracellular transport GO:0032386 101 57 0,000 0,02986317 0,0329742 ! maintenance of location GO:0051235 118 57 0,000 0,02986317 0,03295907 ! hydrogen transport GO:0006818 97 58 0,000 0,03037954 0,0335136 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,03037954 0,03349825 ! regulation of endocytosis GO:0030100 91 58 0,000 0,03037954 0,0334829 ! adult behavior GO:0030534 99 58 0,000 0,03037954 0,03346757 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,03037954 0,03345225 ! positive regulation of secretion GO:0051047 95 59 0,000 0,03089565 0,03400501 ! regulation of cellular component size GO:0032535 109 59 0,000 0,03089565 0,03398946 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,03089565 0,03397392 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,03089565 0,0339584 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,03089565 0,0339429 ! DNA catabolic process GO:0006308 86 59 0,000 0,03089565 0,03392741 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,03089565 0,03391193 ! establishment of organelle localization GO:0051656 109 59 0,000 0,03089565 0,03389646 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,03141151 0,03444672 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,03141151 0,03443103 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,03141151 0,03441535 ! regulation of heart contraction GO:0008016 110 60 0,000 0,03141151 0,03439968 ! camera-type eye development GO:0043010 116 60 0,000 0,03141151 0,03438403 ! protein amino acid autophosphorylation GO:0046777 141 60 0,000 0,03141151 0,0343684 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,03141151 0,03435277 ! kidney development GO:0001822 122 60 0,000 0,03141151 0,03433717 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,03192711 0,03488494 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,03192711 0,0348691 ! mesoderm development GO:0007498 119 61 0,000 0,03192711 0,03485328 ! tRNA processing GO:0008033 89 61 0,000 0,03192711 0,03483748 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,03192711 0,03482168 ! response to peptide hormone stimulus GO:0043434 122 61 0,000 0,03192711 0,03480591 ! ear development GO:0043583 103 62 0,000 0,03244246 0,0353517 ! viral reproductive process GO:0022415 126 62 0,000 0,03244246 0,0353357 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,03244246 0,03531971 ! gonad development GO:0008406 98 62 0,000 0,03244246 0,03530373 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,03244246 0,03528777 ! regulation of mitosis GO:0007088 105 63 0,000 0,03295754 0,03583183 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,03295754 0,03581565 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,03295754 0,03579948 ! detection of external stimulus GO:0009581 91 63 0,000 0,03295754 0,03578333 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,03295754 0,03576719 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,03295754 0,03575106 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,03347237 0,03629316 ! cell redox homeostasis GO:0045454 102 64 0,000 0,03347237 0,03627682 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,03347237 0,03626048 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,03347237 0,03624416 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,03347237 0,03622786 ! positive regulation of cell motion GO:0051272 146 64 0,000 0,03347237 0,03621157 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,03398695 0,03675173 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,03398695 0,03673522 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,03398695 0,03671872 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,03398695 0,03670224 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,03398695 0,03668577 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,03450126 0,03722423 ! actin filament organization GO:0007015 148 66 0,000 0,03450126 0,03720755 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,03450126 0,03719088 ! extracellular matrix organization GO:0030198 133 66 0,000 0,03450126 0,03717422 ! secondary metabolic process GO:0019748 116 66 0,000 0,03450126 0,03715758 ! developmental maturation GO:0021700 116 66 0,000 0,03450126 0,03714095 ! cell projection assembly GO:0030031 120 66 0,000 0,03450126 0,03712434 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,03501532 0,03766064 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,03501532 0,03764382 ! negative regulation of protein kinase activity GO:0006469 130 67 0,000 0,03501532 0,037627 ! negative regulation of cell growth GO:0030308 132 67 0,000 0,03501532 0,03761021 ! activation of MAPK activity GO:0000187 115 67 0,000 0,03501532 0,03759342 ! lung development GO:0030324 144 67 0,000 0,03501532 0,03757665 ! chromosome segregation GO:0007059 113 67 0,000 0,03501532 0,0375599 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,03501532 0,03754316 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,03501532 0,03752644 ! hexose catabolic process GO:0019320 104 67 0,000 0,03501532 0,03750973 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,03501532 0,03749304 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,03501532 0,03747636 ! adaptive immune response GO:0002250 119 67 0,000 0,03501532 0,0374597 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,03501532 0,03744305 ! amino acid transport GO:0006865 125 68 0,000 0,03552912 0,0379756 ! negative regulation of kinase activity GO:0033673 131 68 0,000 0,03552912 0,03795873 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,03552912 0,03794189 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,03552912 0,03792505 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,03552912 0,03790823 ! viral reproduction GO:0016032 134 68 0,000 0,03552912 0,03789143 ! regulation of lipase activity GO:0060191 130 68 0,000 0,03552912 0,03787464 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,03552912 0,03785787 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,03604267 0,03838807 ! negative regulation of cell size GO:0045792 134 69 0,000 0,03604267 0,03837109 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,03604267 0,03835412 ! urogenital system development GO:0001655 137 69 0,000 0,03604267 0,03833716 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,03604267 0,03832022 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,03604267 0,03830329 ! antigen processing and presentation GO:0019882 104 69 0,000 0,03604267 0,03828638 ! appendage morphogenesis GO:0035107 135 70 0,000 0,03655596 0,03881449 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 0,000 0,03655596 0,03879737 ! amine catabolic process GO:0009310 117 71 0,000 0,03706899 0,03932451 ! reproductive structure development GO:0048608 113 71 0,000 0,03706899 0,03930718 ! appendage development GO:0048736 136 71 0,000 0,03706899 0,03928986 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,03706899 0,03927256 ! B cell activation GO:0042113 160 71 0,000 0,03706899 0,03925528 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,03706899 0,03923801 ! regulation of immune effector process GO:0002697 137 71 0,000 0,03706899 0,03922075 ! acute inflammatory response GO:0002526 113 72 0,000 0,03758177 0,03974582 ! regulation of caspase activity GO:0043281 122 72 0,000 0,03758177 0,03972835 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,03758177 0,03971091 ! carbohydrate transport GO:0008643 110 72 0,000 0,03758177 0,03969347 ! negative regulation of transferase activity GO:0051348 140 72 0,000 0,03758177 0,03967606 ! respiratory system development GO:0060541 153 72 0,000 0,03758177 0,03965865 ! learning or memory GO:0007611 147 73 0,000 0,03809429 0,04018187 ! regulation of blood pressure GO:0008217 125 73 0,000 0,03809429 0,04016427 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,03809429 0,04014667 ! axon guidance GO:0007411 139 73 0,000 0,03809429 0,0401291 ! fertilization GO:0009566 90 73 0,000 0,03809429 0,04011153 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,03860655 0,04063314 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,03860655 0,04061538 ! neurotransmitter transport GO:0006836 123 74 0,000 0,03860655 0,04059763 ! meiosis GO:0007126 121 74 0,000 0,03860655 0,04057989 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,03860655 0,04056217 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,03860655 0,04054446 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,03860655 0,04052677 ! regulation of endopeptidase activity GO:0052548 125 74 0,000 0,03860655 0,0405091 ! eye development GO:0001654 143 74 0,000 0,03860655 0,04049144 ! organelle localization GO:0051640 136 74 0,000 0,03860655 0,0404738 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,03911856 0,04099271 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,03911856 0,04097486 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,03911856 0,04095703 ! meiotic cell cycle GO:0051321 122 75 0,000 0,03911856 0,04093922 ! rhythmic process GO:0048511 128 75 0,000 0,03911856 0,04092142 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,03911856 0,04090363 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,03963032 0,04142074 ! defense response to bacterium GO:0042742 89 76 0,000 0,03963032 0,04140275 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,03963032 0,04138478 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,03963032 0,04136683 ! regulation of catabolic process GO:0009894 161 76 0,000 0,03963032 0,04134889 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,04014181 0,04186441 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,04014181 0,04184628 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,04014181 0,04182815 ! blood coagulation GO:0007596 146 78 0,000 0,04065306 0,04234253 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,04065306 0,04232421 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,04065306 0,04230591 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,04065306 0,04228762 ! protein oligomerization GO:0051259 139 78 0,000 0,04065306 0,04226934 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,04116404 0,04278216 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,04116404 0,04276368 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,04116404 0,04274523 ! regulation of peptidase activity GO:0052547 134 79 0,000 0,04116404 0,04272679 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,04116404 0,04270836 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,04167478 0,04321962 ! muscle cell differentiation GO:0042692 159 80 0,000 0,04167478 0,043201 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,04167478 0,04318239 ! protein import into nucleus GO:0006606 158 80 0,000 0,04167478 0,0431638 ! inorganic anion transport GO:0015698 138 80 0,000 0,04167478 0,04314523 ! T cell activation GO:0042110 168 81 0,000 0,04218525 0,04365493 ! response to hypoxia GO:0001666 171 81 0,000 0,04218525 0,04363617 ! digestion GO:0007586 112 81 0,000 0,04218525 0,04361741 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,04218525 0,04359868 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,04218525 0,04357996 ! nuclear import GO:0051170 161 81 0,000 0,04218525 0,04356125 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,04218525 0,04354257 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,04269548 0,04405031 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,04269548 0,04403143 ! response to drug GO:0042493 143 82 0,000 0,04269548 0,04401256 ! response to nutrient GO:0007584 125 82 0,000 0,04269548 0,04399371 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,04269548 0,04397488 ! cellular response to hormone stimulus GO:0032870 167 82 0,000 0,04269548 0,04395606 ! response to oxygen levels GO:0070482 176 83 0,000 0,04320544 0,04446206 ! regulation of lyase activity GO:0051339 160 83 0,000 0,04320544 0,04444305 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,04371516 0,04494815 ! hemostasis GO:0007599 158 84 0,000 0,04371516 0,04492895 ! negative regulation of transport GO:0051051 153 84 0,000 0,04371516 0,04490976 ! negative regulation of growth GO:0045926 155 84 0,000 0,04371516 0,0448906 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,04371516 0,04487144 ! nucleosome assembly GO:0006334 122 85 0,000 0,04422461 0,04537502 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,04422461 0,04535568 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,04422461 0,04533635 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,04473382 0,04583883 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,04473382 0,04581931 ! chromatin assembly GO:0031497 124 86 0,000 0,04473382 0,04579982 ! tube morphogenesis GO:0035239 176 86 0,000 0,04473382 0,04578033 ! mitochondrion organization GO:0007005 148 86 0,000 0,04473382 0,04576087 ! alcohol catabolic process GO:0046164 130 86 0,000 0,04473382 0,04574142 ! amine transport GO:0015837 155 86 0,000 0,04473382 0,04572199 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,04524277 0,04622255 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,04524277 0,04620293 ! protein localization in nucleus GO:0034504 176 87 0,000 0,04524277 0,04618333 ! regulation of protein transport GO:0051223 154 87 0,000 0,04524277 0,04616374 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 135 88 0,000 0,04575146 0,046663 ! regulation of DNA binding GO:0051101 155 88 0,000 0,04575146 0,04664323 ! gland development GO:0048732 206 88 0,000 0,04575146 0,04662347 ! regulation of neurological system process GO:0031644 148 88 0,000 0,04575146 0,04660373 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,04575146 0,04658401 ! cellular defense response GO:0006968 114 89 0,000 0,0462599 0,04708178 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,0462599 0,04706187 ! regulation of cell adhesion GO:0030155 212 89 0,000 0,0462599 0,04704198 ! ossification GO:0001503 188 90 0,000 0,04676809 0,04753867 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,04676809 0,04751859 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,04676809 0,04749853 ! sex differentiation GO:0007548 145 90 0,000 0,04676809 0,04747849 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,04676809 0,04745847 ! bone development GO:0060348 189 91 0,000 0,04727602 0,04795367 ! sterol metabolic process GO:0016125 152 91 0,000 0,04727602 0,04793347 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,04727602 0,04791327 ! regulation of defense response GO:0031347 149 92 0,000 0,0477837 0,04840741 ! nucleosome organization GO:0034728 138 92 0,000 0,0477837 0,04838703 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,0477837 0,04836668 ! vitamin metabolic process GO:0006766 139 92 0,000 0,0477837 0,04834634 ! positive regulation of MAP kinase activity GO:0043406 160 93 0,000 0,04829113 0,0488392 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,04829113 0,04881868 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,04829113 0,04879818 ! regulation of membrane potential GO:0042391 164 93 0,000 0,04829113 0,04877769 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,04829113 0,04875722 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,0487983 0,04924862 ! female pregnancy GO:0007565 164 94 0,000 0,0487983 0,04922797 ! transcription initiation GO:0006352 153 94 0,000 0,0487983 0,04920734 ! regulation of T cell activation GO:0050863 158 94 0,000 0,0487983 0,04918673 ! forebrain development GO:0030900 188 95 0,000 0,04930522 0,04967687 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,04930522 0,04965607 ! leukocyte differentiation GO:0002521 202 96 0,000 0,04981189 0,05014535 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,04981189 0,05012438 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,04981189 0,05010343 ! positive regulation of immune response GO:0050778 156 96 0,000 0,04981189 0,05008249 ! detection of stimulus GO:0051606 151 96 0,000 0,04981189 0,05006157 ! regulation of DNA metabolic process GO:0051052 178 97 0,000 0,0503183 0,05054941 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,0503183 0,05052831 ! protein ubiquitination GO:0016567 217 97 0,000 0,0503183 0,05050723 ! hormone metabolic process GO:0042445 157 97 0,000 0,0503183 0,05048617 ! regulation of protein localization GO:0032880 176 97 0,000 0,0503183 0,05046512 ! response to virus GO:0009615 160 98 0,000 0,05082446 0,05095152 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,05082446 0,0509303 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,05082446 0,05090909 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,05133036 0,05139445 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,05133036 0,05137307 ! skeletal muscle tissue development GO:0007519 186 99 0,000 0,05133036 0,05135171 GO:0060538|skeletal muscle organ development, ! cell cycle arrest GO:0007050 213 100 0,000 0,05183602 0,05183602