pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-b1/out-0.05-06-0.01-300-run-b1//th1-pval-1e-01-08-th2-pval-1e-02-02-th3-pval-1e-01-01-run-b1/go_data/4605-5-real-Desmedt-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! negative regulation of protein ubiquitination GO:0031397 7 5 1,000 2,942E-06 6,767E-03 ! positive regulation of Rho GTPase activity GO:0032321 9 5 1,000 2,942E-06 3,384E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 6,175E-06 4,734E-03 ! regulation of focal adhesion formation GO:0051893 17 7 1,000 6,175E-06 3,551E-03 ! positive regulation of Ras GTPase activity GO:0032320 20 8 1,000 8,231E-06 3,786E-03 ! positive regulation of GTPase activity GO:0043547 21 9 1,000 1,058E-05 4,055E-03 ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 1,000 1,058E-05 3,476E-03 ! regulation of stress fiber formation GO:0051492 20 9 1,000 1,058E-05 3,042E-03 ! regulation of phosphatase activity GO:0010921 21 10 1,000 1,322E-05 3,378E-03 ! regulation of actin filament bundle formation GO:0032231 21 10 1,000 1,322E-05 3,041E-03 ! regulation of Rho GTPase activity GO:0032319 18 11 1,000 1,615E-05 3,377E-03 ! regulation of protein ubiquitination GO:0031396 19 15 1,000 3,08E-05 5,903E-03 ! cellular response to unfolded protein GO:0034620 19 16 1,000 3,519E-05 6,226E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! regulation of dephosphorylation GO:0035303 33 16 1,000 3,519E-05 5,781E-03 ! negative regulation of translation GO:0017148 22 16 1,000 3,519E-05 5,396E-03 ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 6,149E-05 8,839E-03 ! regulation of cell-matrix adhesion GO:0001952 51 22 1,000 6,762E-05 9,148E-03 GO:0010810|regulation of cell-substrate adhesion, ! positive regulation of cell adhesion GO:0045785 37 23 1,000 7,403E-05 9,46E-03 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 7,403E-05 8,962E-03 ! fat cell differentiation GO:0045444 37 24 1,000 8,074E-05 9,285E-03 ! negative regulation of protein modification process GO:0031400 50 26 1,000 9,501E-05 0,0104063 ! DNA damage checkpoint GO:0000077 53 31 1,000 1,357E-04 0,01419056 ! RNA export from nucleus GO:0006405 44 33 1,000 1,54E-04 0,01540318 ! mitotic cell cycle checkpoint GO:0007093 63 34 1,000 1,636E-04 0,01567918 ! DNA integrity checkpoint GO:0031570 57 34 1,000 1,636E-04 0,01505201 ! response to calcium ion GO:0051592 58 40 1,000 2,271E-04 0,0200862 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 1,000 2,626E-04 0,0223719 ! response to insulin stimulus GO:0032868 63 43 1,000 2,626E-04 0,0215729 ! positive regulation of cell cycle GO:0045787 77 45 1,000 2,878E-04 0,02282185 ! response to UV GO:0009411 75 46 1,000 3,007E-04 0,02305686 ! nuclear export GO:0051168 69 48 1,000 3,276E-04 0,0243032 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 1,000 3,699E-04 0,02658756 ! DNA damage response, signal transduction GO:0042770 96 56 1,000 4,461E-04 0,03109298 ! response to peptide hormone stimulus GO:0043434 84 57 1,000 4,622E-04 0,03126633 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 1,000 5,293E-04 0,0347837 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 1,000 5,468E-04 0,03493407 ! cell cycle checkpoint GO:0000075 108 64 1,000 5,826E-04 0,03621461 ! regulation of actin cytoskeleton organization GO:0032956 97 64 1,000 5,826E-04 0,0352616 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 1,000 5,826E-04 0,03435745 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 1,000 6,009E-04 0,03455141 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 1,000 6,009E-04 0,0337087 ! regulation of actin filament-based process GO:0032970 99 66 1,000 6,195E-04 0,03392407 ! regulation of Rho protein signal transduction GO:0035023 111 66 1,000 6,195E-04 0,03313514 ! regulation of Ras GTPase activity GO:0032318 110 68 1,000 6,575E-04 0,03436892 ! positive regulation of ligase activity GO:0051351 99 69 1,000 6,769E-04 0,03459774 ! response to metal ion GO:0010038 103 70 1,000 6,966E-04 0,03483044 ! positive regulation of phosphorylation GO:0042327 102 70 1,000 6,966E-04 0,03408937 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 1,000 7,166E-04 0,0343362 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 1,000 7,368E-04 0,03458592 GO:0045937|positive regulation of phosphate metabolic process, ! response to inorganic substance GO:0010035 115 75 1,000 7,992E-04 0,0367646 ! regulation of ligase activity GO:0051340 114 75 1,000 7,992E-04 0,03604372 ! response to unfolded protein GO:0006986 99 76 1,000 8,206E-04 0,03629491 ! positive regulation of protein modification process GO:0031401 107 78 1,000 8,641E-04 0,0374989 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 1,000 9,087E-04 0,03870502 GO:0010498|proteasomal protein catabolic process, ! regulation of GTPase activity GO:0043087 129 80 1,000 9,087E-04 0,03800129 ! response to protein stimulus GO:0051789 111 81 1,000 9,314E-04 0,03825589 ! regulation of cell adhesion GO:0030155 159 83 1,000 9,777E-04 0,03945148 ! interphase of mitotic cell cycle GO:0051329 156 86 1,000 1,049E-03 0,04160427 ! interphase GO:0051325 159 88 1,000 1,098E-03 0,04280882 ! establishment of RNA localization GO:0051236 128 88 1,000 1,098E-03 0,04209534 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! RNA localization GO:0006403 135 91 1,000 1,174E-03 0,04425269 ! regulation of cytoskeleton organization GO:0051493 154 93 1,000 1,225E-03 0,04545687 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 1,000 1,305E-03 0,04764057 ! regulation of cellular component biogenesis GO:0044087 158 96 1,000 1,305E-03 0,04689619 ! response to light stimulus GO:0009416 153 96 1,000 1,305E-03 0,04617471 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 1,000 1,387E-03 0,04833283 ! regulation of translation GO:0006417 151 100 1,000 1,415E-03 0,04856828 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 2,857E-03 0,09663859 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 2,857E-03 0,09523803 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 2,857E-03 0,09387749 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 2,857E-03 0,09255527 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 2,857E-03 0,09126978 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 2,857E-03 0,09001951 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 2,857E-03 0,08880303 ! sleep GO:0030431 11 5 0,000 2,857E-03 0,08761899 ! negative regulation of bone resorption GO:0045779 10 5 0,000 2,857E-03 0,08646611 ! nucleotide-sugar transport GO:0015780 8 5 0,000 2,857E-03 0,08534317 ! regulation of interferon-beta production GO:0032648 5 5 0,000 2,857E-03 0,08424903 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 2,857E-03 0,08318259 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 2,857E-03 0,0821428 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 2,857E-03 0,0811287 ! tongue development GO:0043586 6 5 0,000 2,857E-03 0,08013932 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 2,857E-03 0,07917379 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 2,857E-03 0,07823124 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 2,857E-03 0,07731087 ! cobalt ion transport GO:0006824 9 5 0,000 2,857E-03 0,07641191 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 2,857E-03 0,07553361 ! SMAD protein complex assembly GO:0007183 9 5 0,000 2,857E-03 0,07467528 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 2,857E-03 0,07383623 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 2,857E-03 0,07301583 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 2,857E-03 0,07221345 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 2,857E-03 0,07142853 ! embryonic camera-type eye development GO:0031076 8 5 0,000 2,857E-03 0,07066048 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 2,857E-03 0,06990877 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 2,857E-03 0,06917289 ! adaptation of signaling pathway GO:0022401 7 5 0,000 2,857E-03 0,06845234 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 2,857E-03 0,06774664 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 2,857E-03 0,06705535 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 2,857E-03 0,06637802 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 2,857E-03 0,06571424 ! positive regulation of histone modification GO:0031058 5 5 0,000 2,857E-03 0,06506361 ! malate metabolic process GO:0006108 7 5 0,000 2,857E-03 0,06442573 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 2,857E-03 0,06380024 ! behavioral response to pain GO:0048266 7 5 0,000 2,857E-03 0,06318677 ! clathrin coat assembly GO:0048268 11 5 0,000 2,857E-03 0,06258499 ! phototransduction, visible light GO:0007603 6 5 0,000 2,857E-03 0,06199457 ! regulation of dopamine uptake GO:0051584 9 5 0,000 2,857E-03 0,06141518 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 2,857E-03 0,06084652 ! mating behavior GO:0007617 6 5 0,000 2,857E-03 0,0602883 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 2,857E-03 0,05974022 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 2,857E-03 0,05920202 ! rhythmic behavior GO:0007622 12 5 0,000 2,857E-03 0,05867343 ! copulation GO:0007620 7 5 0,000 2,857E-03 0,0581542 ! glial cell fate commitment GO:0021781 12 5 0,000 2,857E-03 0,05764407 ! protein maturation by protein folding GO:0022417 12 5 0,000 2,857E-03 0,05714282 ! embryonic hemopoiesis GO:0035162 10 5 0,000 2,857E-03 0,05665021 ! regulation of potassium ion transport GO:0043266 9 5 0,000 2,857E-03 0,05616602 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 2,857E-03 0,05569004 ! apoptotic cell clearance GO:0043277 13 5 0,000 2,857E-03 0,05522205 ! lipoprotein particle clearance GO:0034381 9 5 0,000 2,857E-03 0,05476187 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 2,857E-03 0,05430929 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 2,857E-03 0,05386413 ! response to protozoan GO:0001562 9 5 0,000 2,857E-03 0,05342621 ! positive regulation of glycolysis GO:0045821 11 5 0,000 2,857E-03 0,05299536 ! lymph vessel development GO:0001945 7 5 0,000 2,857E-03 0,05257139 ! endochondral ossification GO:0001958 12 5 0,000 2,857E-03 0,05215416 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 2,857E-03 0,0517435 ! parathyroid gland development GO:0060017 8 5 0,000 2,857E-03 0,05133925 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 2,857E-03 0,05094127 ! anagen GO:0042640 6 5 0,000 2,857E-03 0,05054942 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 2,857E-03 0,05016354 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 2,857E-03 0,04978352 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 2,857E-03 0,04940921 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 2,857E-03 0,04904048 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 2,857E-03 0,04867722 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 2,857E-03 0,0483193 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 2,857E-03 0,0479666 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 2,857E-03 0,04761902 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 2,857E-03 0,04727643 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 2,857E-03 0,04693875 ! cardiac muscle fiber development GO:0048739 7 5 0,000 2,857E-03 0,04660585 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 2,857E-03 0,04627764 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 2,857E-03 0,04595402 ! neutrophil mediated immunity GO:0002446 6 5 0,000 2,857E-03 0,04563489 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 2,857E-03 0,04532017 ! ovulation GO:0030728 6 5 0,000 2,857E-03 0,04500976 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 2,857E-03 0,04470357 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 2,857E-03 0,04440152 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 2,857E-03 0,04410352 ! response to pH GO:0009268 9 5 0,000 2,857E-03 0,0438095 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 2,857E-03 0,04351937 ! proline biosynthetic process GO:0006561 6 5 0,000 2,857E-03 0,04323305 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 2,857E-03 0,04295049 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 2,857E-03 0,04267159 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 2,857E-03 0,04239629 ! polyol catabolic process GO:0046174 7 5 0,000 2,857E-03 0,04212451 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 2,857E-03 0,04185621 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 2,857E-03 0,04159129 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 2,857E-03 0,04132971 ! sister chromatid cohesion GO:0007062 9 5 0,000 2,857E-03 0,0410714 ! nerve growth factor processing GO:0032455 7 5 0,000 2,857E-03 0,0408163 ! urea metabolic process GO:0019627 6 5 0,000 2,857E-03 0,04056435 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 2,857E-03 0,04031549 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 2,857E-03 0,04006966 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 2,857E-03 0,03982681 ! neutrophil activation GO:0042119 5 5 0,000 2,857E-03 0,03958689 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 2,857E-03 0,03934985 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 2,857E-03 0,03911562 ! response to food GO:0032094 5 5 0,000 2,857E-03 0,03888417 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 2,857E-03 0,03865544 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 2,857E-03 0,03842938 ! paraxial mesoderm development GO:0048339 9 5 0,000 2,857E-03 0,03820596 ! forebrain neuron development GO:0021884 7 5 0,000 2,857E-03 0,03798511 ! melanosome organization GO:0032438 7 5 0,000 2,857E-03 0,03776681 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 2,857E-03 0,037551 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 2,857E-03 0,03733764 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 2,857E-03 0,03712669 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 2,857E-03 0,03691811 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 2,857E-03 0,03671187 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 2,857E-03 0,03650791 ! nucleoside transport GO:0015858 6 5 0,000 2,857E-03 0,03630621 ! nucleoside salvage GO:0043174 7 5 0,000 2,857E-03 0,03610673 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 2,857E-03 0,03590942 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 2,857E-03 0,03571426 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 2,857E-03 0,03552121 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 2,857E-03 0,03533024 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 2,857E-03 0,03514131 ! early endosome to late endosome transport GO:0045022 11 5 0,000 2,857E-03 0,03495438 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 2,857E-03 0,03476944 ! depyrimidination GO:0045008 8 5 0,000 2,857E-03 0,03458644 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 2,857E-03 0,03440536 ! 5S class rRNA transcription GO:0042791 8 5 0,000 2,857E-03 0,03422617 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 2,857E-03 0,03404883 ! regulation of centrosome cycle GO:0046605 7 5 0,000 2,857E-03 0,03387332 ! neuronal ion channel clustering GO:0045161 7 5 0,000 2,857E-03 0,03369961 ! sodium ion homeostasis GO:0055078 6 5 0,000 2,857E-03 0,03352768 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 2,857E-03 0,03335748 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 2,857E-03 0,03318901 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 2,857E-03 0,03302223 ! monocyte differentiation GO:0030224 8 5 0,000 2,857E-03 0,03285712 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 2,857E-03 0,03269365 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 2,857E-03 0,0325318 ! centrosome duplication GO:0051298 5 5 0,000 2,857E-03 0,03237155 ! response to UV-C GO:0010225 6 5 0,000 2,857E-03 0,03221286 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 2,857E-03 0,03205573 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 2,857E-03 0,03190012 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 2,857E-03 0,03174601 ! regulation of dendrite development GO:0050773 12 5 0,000 2,857E-03 0,03159339 ! peptidyl-arginine modification GO:0018195 7 5 0,000 2,857E-03 0,03144222 ! positive regulation of organ growth GO:0046622 6 5 0,000 2,857E-03 0,0312925 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 2,857E-03 0,03114419 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 2,857E-03 0,03099728 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 2,857E-03 0,03085176 ! regulation of dopamine secretion GO:0014059 12 5 0,000 2,857E-03 0,03070759 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 2,857E-03 0,03056476 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 2,857E-03 0,03042326 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 2,857E-03 0,03028306 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 2,857E-03 0,03014415 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 2,857E-03 0,0300065 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 2,857E-03 0,02987011 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 2,857E-03 0,02973495 ! neural tube patterning GO:0021532 6 5 0,000 2,857E-03 0,02960101 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 2,857E-03 0,02946827 ! histone demethylation GO:0016577 9 5 0,000 2,857E-03 0,02933672 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 2,857E-03 0,02920633 ! regulation of sterol transport GO:0032371 7 5 0,000 2,857E-03 0,0290771 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 2,857E-03 0,02894901 ! enteric nervous system development GO:0048484 8 5 0,000 2,857E-03 0,02882204 ! establishment of planar polarity GO:0001736 6 5 0,000 2,857E-03 0,02869618 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 2,857E-03 0,02857141 ! muscle cell proliferation GO:0033002 8 5 0,000 2,857E-03 0,02844772 ! transcription termination GO:0006353 8 5 0,000 2,857E-03 0,0283251 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 2,857E-03 0,02820354 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 2,857E-03 0,02808301 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 2,857E-03 0,02796351 ! regulation of respiratory burst GO:0060263 8 5 0,000 2,857E-03 0,02784502 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 2,857E-03 0,02772753 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 2,857E-03 0,02761103 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 2,857E-03 0,0274955 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 2,857E-03 0,02738093 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 2,857E-03 0,02726732 ! apical protein localization GO:0045176 6 5 0,000 2,857E-03 0,02715465 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 2,857E-03 0,0270429 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 2,857E-03 0,02693207 ! galactolipid metabolic process GO:0019374 7 5 0,000 2,857E-03 0,02682214 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 2,857E-03 0,02671311 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 2,857E-03 0,02660496 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 2,857E-03 0,02649768 ! triglyceride catabolic process GO:0019433 6 5 0,000 2,857E-03 0,02639126 ! glial cell migration GO:0008347 10 5 0,000 2,857E-03 0,0262857 ! determination of adult lifespan GO:0008340 8 5 0,000 2,857E-03 0,02618097 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 2,857E-03 0,02607708 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 2,857E-03 0,02597401 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 2,857E-03 0,02587175 ! somatic stem cell maintenance GO:0035019 13 5 0,000 2,857E-03 0,02577029 ! cerebellar cortex formation GO:0021697 6 5 0,000 2,857E-03 0,02566963 ! neural plate development GO:0001840 6 5 0,000 2,857E-03 0,02556974 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 2,857E-03 0,02547064 ! regulation of sensory perception GO:0051931 6 5 0,000 2,857E-03 0,02537229 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 2,857E-03 0,02527471 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 2,857E-03 0,02517787 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 2,857E-03 0,02508177 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 2,857E-03 0,0249864 ! sensory cilium assembly GO:0035058 6 5 0,000 2,857E-03 0,02489176 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 2,857E-03 0,02479783 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 2,857E-03 0,0247046 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 2,857E-03 0,02461208 ! spindle assembly GO:0051225 5 5 0,000 2,857E-03 0,02452024 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 2,857E-03 0,02442909 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 2,857E-03 0,02433861 ! protein amino acid prenylation GO:0018346 9 5 0,000 2,857E-03 0,0242488 ! organ regeneration GO:0031100 7 5 0,000 2,857E-03 0,02415965 ! NAD biosynthetic process GO:0009435 7 5 0,000 2,857E-03 0,02407115 ! carnitine metabolic process GO:0009437 5 5 0,000 2,857E-03 0,0239833 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 2,857E-03 0,02389609 ! cellular anion homeostasis GO:0030002 6 5 0,000 2,857E-03 0,02380951 GO:0055081|anion homeostasis, ! tRNA transcription GO:0009304 11 6 0,000 3,428E-03 0,02846094 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 3,428E-03 0,02835856 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 3,428E-03 0,02825692 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 3,428E-03 0,028156 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 3,428E-03 0,0280558 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 3,428E-03 0,02795631 ! regulation of helicase activity GO:0051095 11 6 0,000 3,428E-03 0,02785753 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 3,428E-03 0,02775944 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 3,428E-03 0,02766203 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 3,428E-03 0,02756531 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 3,428E-03 0,02746927 ! positive regulation of axon extension GO:0045773 8 6 0,000 3,428E-03 0,02737389 ! prostate gland development GO:0030850 9 6 0,000 3,428E-03 0,02727917 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 3,428E-03 0,0271851 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 3,428E-03 0,02709168 ! forebrain neuron differentiation GO:0021879 9 6 0,000 3,428E-03 0,0269989 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 3,428E-03 0,02690676 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 3,428E-03 0,02681524 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 3,428E-03 0,02672434 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 3,428E-03 0,02663405 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 3,428E-03 0,02654438 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 3,428E-03 0,0264553 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 3,428E-03 0,02636682 ! neuron adhesion GO:0007158 9 6 0,000 3,428E-03 0,02627893 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 3,428E-03 0,02619163 ! establishment of tissue polarity GO:0007164 7 6 0,000 3,428E-03 0,0261049 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 3,428E-03 0,02601874 ! signal peptide processing GO:0006465 8 6 0,000 3,428E-03 0,02593316 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 3,428E-03 0,02584813 ! mRNA stabilization GO:0048255 15 6 0,000 3,428E-03 0,02576366 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 3,428E-03 0,02567974 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 3,428E-03 0,02559636 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 3,428E-03 0,02551353 ! opsonization GO:0008228 8 6 0,000 3,428E-03 0,02543122 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 3,428E-03 0,02534945 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 3,428E-03 0,0252682 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 3,428E-03 0,02518747 ! protein amino acid dealkylation GO:0008214 11 6 0,000 3,428E-03 0,02510726 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 3,428E-03 0,02502755 ! photoreceptor cell development GO:0042461 10 6 0,000 3,428E-03 0,02494835 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 3,428E-03 0,02486965 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 3,428E-03 0,02479145 ! mechanosensory behavior GO:0007638 8 6 0,000 3,428E-03 0,02471373 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 3,428E-03 0,0246365 ! negative regulation of endocytosis GO:0045806 8 6 0,000 3,428E-03 0,02455975 ! response to interferon-gamma GO:0034341 12 6 0,000 3,428E-03 0,02448348 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 3,428E-03 0,02440768 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 3,428E-03 0,02433234 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 3,428E-03 0,02425748 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 3,428E-03 0,02418307 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 3,428E-03 0,02410911 ! cGMP-mediated signaling GO:0019934 10 6 0,000 3,428E-03 0,02403561 ! activation of MAPKKK activity GO:0000185 10 6 0,000 3,428E-03 0,02396255 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 3,428E-03 0,02388994 ! thymic T cell selection GO:0045061 12 6 0,000 3,428E-03 0,02381776 ! protein lipoylation GO:0009249 10 6 0,000 3,428E-03 0,02374602 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 3,428E-03 0,02367471 ! pigment granule organization GO:0048753 11 6 0,000 3,428E-03 0,02360383 ! drug transport GO:0015893 6 6 0,000 3,428E-03 0,02353337 ! cysteine metabolic process GO:0006534 7 6 0,000 3,428E-03 0,02346333 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 3,428E-03 0,02339371 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 3,428E-03 0,0233245 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 3,428E-03 0,02325569 ! histidine metabolic process GO:0006547 6 6 0,000 3,428E-03 0,02318729 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 3,428E-03 0,0231193 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 3,428E-03 0,02305169 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 3,428E-03 0,02298449 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 3,428E-03 0,02291767 ! adenohypophysis development GO:0021984 10 6 0,000 3,428E-03 0,02285125 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 3,428E-03 0,0227852 ! hyperosmotic response GO:0006972 8 6 0,000 3,428E-03 0,02271954 ! microtubule nucleation GO:0007020 10 6 0,000 3,428E-03 0,02265425 ! ER overload response GO:0006983 7 6 0,000 3,428E-03 0,02258934 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 3,428E-03 0,0225248 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 3,428E-03 0,02246063 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 3,428E-03 0,02239682 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 3,428E-03 0,02233337 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 3,428E-03 0,02227028 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 3,428E-03 0,02220755 ! response to dietary excess GO:0002021 7 6 0,000 3,428E-03 0,02214517 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 3,428E-03 0,02208314 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 3,428E-03 0,02202145 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 3,428E-03 0,02196011 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 3,428E-03 0,02189911 ! glycerol ether catabolic process GO:0044269 8 6 0,000 3,428E-03 0,02183845 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 3,428E-03 0,02177812 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 3,428E-03 0,02171813 ! neuron apoptosis GO:0051402 8 6 0,000 3,428E-03 0,02165846 ! organic alcohol transport GO:0015850 9 6 0,000 3,428E-03 0,02159912 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 3,428E-03 0,02154011 ! T cell mediated immunity GO:0002456 12 6 0,000 3,428E-03 0,02148142 ! male sex determination GO:0030238 9 6 0,000 3,428E-03 0,02142304 ! carnitine transport GO:0015879 8 6 0,000 3,428E-03 0,02136499 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 3,428E-03 0,02130724 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 3,428E-03 0,02124981 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 3,428E-03 0,02119269 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 3,428E-03 0,02113587 ! positive regulation of exocytosis GO:0045921 6 6 0,000 3,428E-03 0,02107936 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 3,428E-03 0,02102315 ! parturition GO:0007567 12 6 0,000 3,428E-03 0,02096723 ! negative regulation of translational initiation GO:0045947 7 6 0,000 3,428E-03 0,02091162 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 3,428E-03 0,0208563 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 3,428E-03 0,02080127 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 3,428E-03 0,02074653 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 3,428E-03 0,02069207 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 3,428E-03 0,0206379 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 3,428E-03 0,02058402 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 3,428E-03 0,02053042 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 3,428E-03 0,02047709 ! macrophage differentiation GO:0030225 10 6 0,000 3,428E-03 0,02042404 ! astrocyte development GO:0014002 14 6 0,000 3,428E-03 0,02037127 ! hyaluronan metabolic process GO:0030212 6 6 0,000 3,428E-03 0,02031876 ! purine base biosynthetic process GO:0009113 14 6 0,000 3,428E-03 0,02026653 ! interaction with symbiont GO:0051702 8 6 0,000 3,428E-03 0,02021456 ! anterograde axon cargo transport GO:0008089 8 6 0,000 3,428E-03 0,02016286 ! skeletal muscle contraction GO:0003009 6 6 0,000 3,428E-03 0,02011143 ! eating behavior GO:0042755 6 6 0,000 3,428E-03 0,02006025 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 3,428E-03 0,02000934 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 3,428E-03 0,01995868 ! response to copper ion GO:0046688 9 6 0,000 3,428E-03 0,01990828 ! DNA topological change GO:0006265 8 6 0,000 3,428E-03 0,01985814 ! response to exogenous dsRNA GO:0043330 8 6 0,000 3,428E-03 0,01980824 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 3,428E-03 0,0197586 ! establishment of melanosome localization GO:0032401 9 6 0,000 3,428E-03 0,0197092 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 3,428E-03 0,01966005 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 3,428E-03 0,01961114 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 3,428E-03 0,01956248 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 3,428E-03 0,01951406 ! nucleoside catabolic process GO:0009164 6 6 0,000 3,428E-03 0,01946588 ! gas homeostasis GO:0033483 11 6 0,000 3,428E-03 0,01941793 ! hair follicle maturation GO:0048820 7 6 0,000 3,428E-03 0,01937022 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 3,428E-03 0,01932274 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 3,428E-03 0,0192755 ! Schwann cell development GO:0014044 14 6 0,000 3,428E-03 0,01922849 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 3,428E-03 0,0191817 ! dendrite morphogenesis GO:0048813 9 6 0,000 3,428E-03 0,01913514 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 3,428E-03 0,01908881 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 3,428E-03 0,0190427 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 3,428E-03 0,01899682 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 3,428E-03 0,01895115 ! histone ubiquitination GO:0016574 7 6 0,000 3,428E-03 0,01890571 ! regulation of meiosis GO:0040020 10 6 0,000 3,428E-03 0,01886048 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 3,428E-03 0,01881546 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 3,428E-03 0,01877067 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 3,428E-03 0,01872608 ! regulation of mast cell activation GO:0033003 6 6 0,000 3,428E-03 0,01868171 ! membrane to membrane docking GO:0022614 12 6 0,000 3,428E-03 0,01863754 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 3,428E-03 0,01859358 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 3,428E-03 0,01854983 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 3,428E-03 0,01850629 ! receptor internalization GO:0031623 9 6 0,000 3,428E-03 0,01846295 ! neutrophil homeostasis GO:0001780 6 6 0,000 3,428E-03 0,01841981 ! coenzyme A metabolic process GO:0015936 9 6 0,000 3,428E-03 0,01837688 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 3,428E-03 0,01833414 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 3,428E-03 0,0182916 ! protein deubiquitination GO:0016579 8 6 0,000 3,428E-03 0,01824926 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 3,428E-03 0,01820711 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 3,428E-03 0,01816516 ! peptidyl-histidine modification GO:0018202 9 6 0,000 3,428E-03 0,0181234 ! axonal fasciculation GO:0007413 9 6 0,000 3,428E-03 0,01808183 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 3,428E-03 0,01804046 ! thiamin metabolic process GO:0006772 6 6 0,000 3,428E-03 0,01799927 ! midbrain development GO:0030901 6 6 0,000 3,428E-03 0,01795827 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 3,428E-03 0,01791745 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 3,428E-03 0,01787682 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 3,428E-03 0,01783638 ! progesterone metabolic process GO:0042448 8 6 0,000 3,428E-03 0,01779612 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 3,428E-03 0,01775604 ! glycolipid catabolic process GO:0019377 13 6 0,000 3,428E-03 0,01771613 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 3,428E-03 0,01767641 ! positive regulation of glucose import GO:0046326 6 6 0,000 3,428E-03 0,01763687 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 3,428E-03 0,0175975 ! adult feeding behavior GO:0008343 6 6 0,000 3,428E-03 0,01755831 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 3,428E-03 0,01751929 ! blastocyst growth GO:0001832 15 6 0,000 3,428E-03 0,01748044 ! pigment granule transport GO:0051904 12 6 0,000 3,428E-03 0,01744177 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 3,428E-03 0,01740327 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 3,428E-03 0,01736493 ! catecholamine transport GO:0051937 7 6 0,000 3,428E-03 0,01732677 ! organ or tissue specific immune response GO:0002251 7 6 0,000 3,428E-03 0,01728877 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 3,428E-03 0,01725094 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 3,428E-03 0,01721327 ! negative regulation of B cell activation GO:0050869 9 6 0,000 3,428E-03 0,01717577 ! protein prenylation GO:0018342 10 6 0,000 3,428E-03 0,01713843 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 3,428E-03 0,01710126 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 3,428E-03 0,01706424 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 3,428E-03 0,01702739 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 3,428E-03 0,01699069 ! positive regulation of coagulation GO:0050820 11 6 0,000 3,428E-03 0,01695415 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 3,998E-03 0,01973232 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 3,998E-03 0,01969006 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 3,998E-03 0,01964799 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 3,998E-03 0,0196061 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 3,998E-03 0,01956438 ! synaptonemal complex assembly GO:0007130 10 7 0,000 3,998E-03 0,01952284 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 3,998E-03 0,01948148 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 3,998E-03 0,01944029 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 3,998E-03 0,01939928 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 3,998E-03 0,01935844 ! reproductive behavior GO:0019098 12 7 0,000 3,998E-03 0,01931777 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 3,998E-03 0,01927727 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 3,998E-03 0,01923694 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 3,998E-03 0,01919678 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 3,998E-03 0,01915679 ! oligopeptide transport GO:0006857 11 7 0,000 3,998E-03 0,01911696 ! protein amino acid sulfation GO:0006477 9 7 0,000 3,998E-03 0,0190773 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 3,998E-03 0,0190378 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 3,998E-03 0,01899847 ! RNA methylation GO:0001510 11 7 0,000 3,998E-03 0,0189593 ! pericardium development GO:0060039 8 7 0,000 3,998E-03 0,01892029 ! macrophage chemotaxis GO:0048246 10 7 0,000 3,998E-03 0,01888144 ! fibril organization GO:0043206 13 7 0,000 3,998E-03 0,01884274 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 3,998E-03 0,01880421 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 3,998E-03 0,01876583 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 3,998E-03 0,01872762 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 3,998E-03 0,01868955 ! lipoprotein transport GO:0042953 9 7 0,000 3,998E-03 0,01865164 ! cerebral cortex cell migration GO:0021795 11 7 0,000 3,998E-03 0,01861388 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 3,998E-03 0,01857628 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 3,998E-03 0,01853883 ! estrogen metabolic process GO:0008210 14 7 0,000 3,998E-03 0,01850153 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 3,998E-03 0,01846438 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 3,998E-03 0,01842737 ! chemosensory behavior GO:0007635 9 7 0,000 3,998E-03 0,01839052 ! microtubule bundle formation GO:0001578 8 7 0,000 3,998E-03 0,01835381 ! T-helper 1 type immune response GO:0042088 11 7 0,000 3,998E-03 0,01831725 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 3,998E-03 0,01828083 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 3,998E-03 0,01824456 ! leukocyte degranulation GO:0043299 10 7 0,000 3,998E-03 0,01820843 ! bile acid and bile salt transport GO:0015721 9 7 0,000 3,998E-03 0,01817245 ! reflex GO:0060004 12 7 0,000 3,998E-03 0,01813661 ! positive regulation of isotype switching GO:0045830 15 7 0,000 3,998E-03 0,0181009 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 3,998E-03 0,01806534 ! protein-cofactor linkage GO:0018065 13 7 0,000 3,998E-03 0,01802992 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 3,998E-03 0,01799464 ! glycerolipid catabolic process GO:0046503 9 7 0,000 3,998E-03 0,01795949 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 3,998E-03 0,01792448 ! spinal cord patterning GO:0021511 7 7 0,000 3,998E-03 0,01788961 ! hemoglobin metabolic process GO:0020027 10 7 0,000 3,998E-03 0,01785487 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 3,998E-03 0,01782027 ! adrenal gland development GO:0030325 17 7 0,000 3,998E-03 0,0177858 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 3,998E-03 0,01775147 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 3,998E-03 0,01771726 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 3,998E-03 0,01768319 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 3,998E-03 0,01764925 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 3,998E-03 0,01761544 ! endosome organization GO:0007032 10 7 0,000 3,998E-03 0,01758176 ! thyroid hormone generation GO:0006590 11 7 0,000 3,998E-03 0,0175482 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 3,998E-03 0,01751478 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 3,998E-03 0,01748148 ! regulation of pigmentation during development GO:0048070 15 7 0,000 3,998E-03 0,01744831 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 3,998E-03 0,01741526 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 3,998E-03 0,01738234 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 3,998E-03 0,01734955 ! galactose metabolic process GO:0006012 10 7 0,000 3,998E-03 0,01731687 ! vesicle fusion GO:0006906 15 7 0,000 3,998E-03 0,01728432 ! intracellular pH reduction GO:0051452 10 7 0,000 3,998E-03 0,01725189 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 3,998E-03 0,01721959 ! organ growth GO:0035265 11 7 0,000 3,998E-03 0,0171874 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 3,998E-03 0,01715533 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 3,998E-03 0,01712339 ! Rac protein signal transduction GO:0016601 7 7 0,000 3,998E-03 0,01709156 ! retinol metabolic process GO:0042572 9 7 0,000 3,998E-03 0,01705985 ! behavioral fear response GO:0001662 13 7 0,000 3,998E-03 0,01702826 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 3,998E-03 0,01699678 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 3,998E-03 0,01696542 ! rRNA modification GO:0000154 12 7 0,000 3,998E-03 0,01693418 ! protein heterooligomerization GO:0051291 10 7 0,000 3,998E-03 0,01690305 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 3,998E-03 0,01687204 ! response to UV-B GO:0010224 11 7 0,000 3,998E-03 0,01684113 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 3,998E-03 0,01681035 ! protein retention in ER lumen GO:0006621 12 7 0,000 3,998E-03 0,01677967 ! intermediate filament organization GO:0045109 11 7 0,000 3,998E-03 0,01674911 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 3,998E-03 0,01671865 ! cardiac muscle cell development GO:0055013 9 7 0,000 3,998E-03 0,01668831 ! fibrinolysis GO:0042730 9 7 0,000 3,998E-03 0,01665808 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 3,998E-03 0,01662795 ! regulation of circadian rhythm GO:0042752 11 7 0,000 3,998E-03 0,01659794 ! B cell lineage commitment GO:0002326 17 7 0,000 3,998E-03 0,01656803 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 3,998E-03 0,01653824 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 3,998E-03 0,01650854 ! response to tropane GO:0014073 13 7 0,000 3,998E-03 0,01647896 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 3,998E-03 0,01644948 ! melanosome localization GO:0032400 10 7 0,000 3,998E-03 0,01642011 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 3,998E-03 0,01639084 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 3,998E-03 0,01636167 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 3,998E-03 0,01633261 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 3,998E-03 0,01630365 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 3,998E-03 0,01627479 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 3,998E-03 0,01624604 ! mast cell activation GO:0045576 9 7 0,000 3,998E-03 0,01621739 ! multicellular organismal aging GO:0010259 11 7 0,000 3,998E-03 0,01618884 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 3,998E-03 0,01616039 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 3,998E-03 0,01613203 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 3,998E-03 0,01610378 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 3,998E-03 0,01607563 ! establishment of nucleus localization GO:0040023 13 7 0,000 3,998E-03 0,01604757 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 3,998E-03 0,01601962 ! T cell lineage commitment GO:0002360 12 7 0,000 3,998E-03 0,01599175 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 3,998E-03 0,01596399 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 3,998E-03 0,01593632 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 3,998E-03 0,01590875 ! regulation of lipid transport GO:0032368 13 7 0,000 3,998E-03 0,01588128 ! response to tumor cell GO:0002347 12 7 0,000 3,998E-03 0,0158539 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 3,998E-03 0,01582661 ! neuroblast proliferation GO:0007405 13 7 0,000 3,998E-03 0,01579941 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 3,998E-03 0,01577231 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 3,998E-03 0,01574531 ! peptidyl-threonine modification GO:0018210 18 7 0,000 3,998E-03 0,01571839 ! diuresis GO:0030146 12 7 0,000 3,998E-03 0,01569157 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 3,998E-03 0,01566484 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 3,998E-03 0,0156382 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 3,998E-03 0,01561165 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 3,998E-03 0,01558518 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 3,998E-03 0,01555881 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 3,998E-03 0,01553253 ! melanin biosynthetic process GO:0042438 8 7 0,000 3,998E-03 0,01550634 ! regulation of synaptogenesis GO:0051963 10 7 0,000 3,998E-03 0,01548023 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 3,998E-03 0,01545422 ! dopamine biosynthetic process GO:0042416 15 7 0,000 3,998E-03 0,01542829 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 3,998E-03 0,01540244 ! lymph node development GO:0048535 9 7 0,000 3,998E-03 0,01537669 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 3,998E-03 0,01535102 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 3,998E-03 0,01532543 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 3,998E-03 0,01529993 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 3,998E-03 0,01527452 ! endosome to lysosome transport GO:0008333 10 7 0,000 3,998E-03 0,01524919 ! ATP catabolic process GO:0006200 10 7 0,000 3,998E-03 0,01522394 ! establishment of pigment granule localization GO:0051905 13 7 0,000 3,998E-03 0,01519878 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 3,998E-03 0,01517369 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 3,998E-03 0,0151487 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 3,998E-03 0,01512378 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 3,998E-03 0,01509895 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 3,998E-03 0,0150742 ! muscle adaptation GO:0043500 12 7 0,000 3,998E-03 0,01504952 ! amino sugar catabolic process GO:0046348 9 7 0,000 3,998E-03 0,01502493 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 3,998E-03 0,01500042 ! retina homeostasis GO:0001895 9 7 0,000 3,998E-03 0,01497599 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 3,998E-03 0,01495164 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 3,998E-03 0,01492737 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 3,998E-03 0,01490318 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 3,998E-03 0,01487906 ! behavioral response to nicotine GO:0035095 11 7 0,000 3,998E-03 0,01485502 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 3,998E-03 0,01483106 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 3,998E-03 0,01480718 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 4,568E-03 0,01689094 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 4,568E-03 0,01686383 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 4,568E-03 0,0168368 ! axon extension GO:0048675 11 8 0,000 4,568E-03 0,01680986 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 4,568E-03 0,01678301 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 4,568E-03 0,01675624 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 4,568E-03 0,01672956 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 4,568E-03 0,01670296 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 4,568E-03 0,01667645 ! cell proliferation in forebrain GO:0021846 10 8 0,000 4,568E-03 0,01665002 ! positive regulation of B cell proliferation GO:0030890 11 8 0,000 4,568E-03 0,01662368 ! phosphate transport GO:0006817 10 8 0,000 4,568E-03 0,01659741 ! N-glycan processing GO:0006491 12 8 0,000 4,568E-03 0,01657124 ! Golgi to endosome transport GO:0006895 16 8 0,000 4,568E-03 0,01654514 ! UTP metabolic process GO:0046051 8 8 0,000 4,568E-03 0,01651912 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 4,568E-03 0,01649319 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 4,568E-03 0,01646734 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 4,568E-03 0,01644157 ! neurotransmitter uptake GO:0001504 10 8 0,000 4,568E-03 0,01641588 ! succinate metabolic process GO:0006105 14 8 0,000 4,568E-03 0,01639027 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 4,568E-03 0,01636474 ! smoothened signaling pathway GO:0007224 8 8 0,000 4,568E-03 0,01633929 ! membrane hyperpolarization GO:0060081 10 8 0,000 4,568E-03 0,01631392 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 4,568E-03 0,01628862 ! keratinocyte proliferation GO:0043616 12 8 0,000 4,568E-03 0,01626341 ! middle ear morphogenesis GO:0042474 9 8 0,000 4,568E-03 0,01623827 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 4,568E-03 0,01621321 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 4,568E-03 0,01618823 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 4,568E-03 0,01616333 ! ganglioside metabolic process GO:0001573 15 8 0,000 4,568E-03 0,0161385 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 4,568E-03 0,01611375 ! pseudouridine synthesis GO:0001522 9 8 0,000 4,568E-03 0,01608907 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 4,568E-03 0,01606447 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 4,568E-03 0,01603994 ! endothelial cell differentiation GO:0045446 14 8 0,000 4,568E-03 0,01601549 ! ceramide biosynthetic process GO:0046513 9 8 0,000 4,568E-03 0,01599112 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 4,568E-03 0,01596681 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 0,000 4,568E-03 0,01594258 ! astrocyte differentiation GO:0048708 16 8 0,000 4,568E-03 0,01591843 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 4,568E-03 0,01589435 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 4,568E-03 0,01587034 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 4,568E-03 0,0158464 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 4,568E-03 0,01582253 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 4,568E-03 0,01579874 ! melanin metabolic process GO:0006582 12 8 0,000 4,568E-03 0,01577502 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 4,568E-03 0,01575137 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 4,568E-03 0,01572779 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 4,568E-03 0,01570428 ! macrophage activation GO:0042116 12 8 0,000 4,568E-03 0,01568084 ! regulation of type I interferon production GO:0032479 8 8 0,000 4,568E-03 0,01565747 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 4,568E-03 0,01563417 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 4,568E-03 0,01561094 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 4,568E-03 0,01558778 ! regulation of vascular permeability GO:0043114 12 8 0,000 4,568E-03 0,01556469 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 4,568E-03 0,01554166 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 4,568E-03 0,0155187 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 4,568E-03 0,01549582 ! ruffle organization GO:0031529 11 8 0,000 4,568E-03 0,01547299 ! osteoblast development GO:0002076 13 8 0,000 4,568E-03 0,01545024 ! lens development in camera-type eye GO:0002088 10 8 0,000 4,568E-03 0,01542755 ! positive regulation of vasodilation GO:0045909 12 8 0,000 4,568E-03 0,01540493 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 4,568E-03 0,01538238 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 4,568E-03 0,01535989 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 4,568E-03 0,01533746 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 4,568E-03 0,01531511 ! Schwann cell differentiation GO:0014037 17 8 0,000 4,568E-03 0,01529281 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 4,568E-03 0,01527059 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 4,568E-03 0,01524842 ! regulation of gliogenesis GO:0014013 20 8 0,000 4,568E-03 0,01522632 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 4,568E-03 0,01520429 ! oligodendrocyte development GO:0014003 8 8 0,000 4,568E-03 0,01518232 ! segment specification GO:0007379 10 8 0,000 4,568E-03 0,01516041 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 4,568E-03 0,01513856 ! cellular extravasation GO:0045123 11 8 0,000 4,568E-03 0,01511678 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 4,568E-03 0,01509506 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 4,568E-03 0,0150734 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 4,568E-03 0,01505181 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 4,568E-03 0,01503028 ! snRNA metabolic process GO:0016073 10 8 0,000 4,568E-03 0,0150088 GO:0016180|snRNA processing, ! phosphoinositide 3-kinase cascade GO:0014065 23 8 0,000 4,568E-03 0,01498739 ! regulation of interleukin-4 production GO:0032673 16 8 0,000 4,568E-03 0,01496604 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 4,568E-03 0,01494476 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 4,568E-03 0,01492353 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 4,568E-03 0,01490236 ! nucleosome disassembly GO:0006337 12 8 0,000 4,568E-03 0,01488125 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 4,568E-03 0,0148602 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! protein import into peroxisome matrix GO:0016558 14 8 0,000 4,568E-03 0,01483921 ! icosanoid secretion GO:0032309 12 8 0,000 4,568E-03 0,01481828 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 4,568E-03 0,01479741 ! leukocyte activation during immune response GO:0002366 13 8 0,000 4,568E-03 0,0147766 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 4,568E-03 0,01475585 ! cerebellum morphogenesis GO:0021587 9 8 0,000 4,568E-03 0,01473515 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 4,568E-03 0,01471451 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 4,568E-03 0,01469393 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 4,568E-03 0,01467341 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 4,568E-03 0,01465295 ! sterol catabolic process GO:0016127 9 8 0,000 4,568E-03 0,01463254 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 4,568E-03 0,01461219 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 4,568E-03 0,01459189 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 4,568E-03 0,01457165 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 4,568E-03 0,01455147 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 4,568E-03 0,01453135 ! prophase GO:0051324 11 8 0,000 4,568E-03 0,01451128 ! S phase GO:0051320 8 8 0,000 4,568E-03 0,01449126 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 4,568E-03 0,0144713 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 4,568E-03 0,01445139 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 4,568E-03 0,01443154 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 4,568E-03 0,01441175 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 4,568E-03 0,014392 ! hormone catabolic process GO:0042447 13 8 0,000 4,568E-03 0,01437232 ! quaternary ammonium group transport GO:0015697 10 8 0,000 4,568E-03 0,01435268 ! myeloid cell homeostasis GO:0002262 8 8 0,000 4,568E-03 0,0143331 ! regulation of fibrinolysis GO:0051917 13 8 0,000 4,568E-03 0,01431357 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 4,568E-03 0,0142941 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 4,568E-03 0,01427468 ! regulation of telomere maintenance GO:0032204 10 8 0,000 4,568E-03 0,01425531 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 4,568E-03 0,01423599 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 4,568E-03 0,01421673 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 4,568E-03 0,01419752 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 4,568E-03 0,01417836 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 4,568E-03 0,01415925 ! lamellipodium assembly GO:0030032 9 8 0,000 4,568E-03 0,01414019 ! regulation of embryonic development GO:0045995 16 8 0,000 4,568E-03 0,01412119 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 4,568E-03 0,01410223 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 4,568E-03 0,01408333 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 4,568E-03 0,01406448 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 5,138E-03 0,01579732 ! regulation of developmental growth GO:0048638 13 9 0,000 5,138E-03 0,01577622 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 5,138E-03 0,01575519 ! telencephalon cell migration GO:0022029 16 9 0,000 5,138E-03 0,01573421 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 5,138E-03 0,01571329 ! pentose-phosphate shunt GO:0006098 12 9 0,000 5,138E-03 0,01569242 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 5,138E-03 0,01567161 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 5,138E-03 0,01565085 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 5,138E-03 0,01563015 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 5,138E-03 0,0156095 ! GTP metabolic process GO:0046039 9 9 0,000 5,138E-03 0,01558891 ! elastic fiber assembly GO:0048251 13 9 0,000 5,138E-03 0,01556837 ! social behavior GO:0035176 14 9 0,000 5,138E-03 0,01554788 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 5,138E-03 0,01552745 ! artery development GO:0060840 19 9 0,000 5,138E-03 0,01550708 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 5,138E-03 0,01548675 ! regulation of glycolysis GO:0006110 15 9 0,000 5,138E-03 0,01546648 ! response to pain GO:0048265 16 9 0,000 5,138E-03 0,01544626 ! protein complex disassembly GO:0043241 17 9 0,000 5,138E-03 0,0154261 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 5,138E-03 0,01540599 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 5,138E-03 0,01538593 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 5,138E-03 0,01536592 ! lung alveolus development GO:0048286 17 9 0,000 5,138E-03 0,01534596 ! ciliary or flagellar motility GO:0001539 10 9 0,000 5,138E-03 0,01532606 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 5,138E-03 0,01530621 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 5,138E-03 0,01528641 ! regulation of exit from mitosis GO:0007096 12 9 0,000 5,138E-03 0,01526666 ! ventral spinal cord development GO:0021517 11 9 0,000 5,138E-03 0,01524696 ! protein targeting to ER GO:0045047 19 9 0,000 5,138E-03 0,01522731 ! T cell selection GO:0045058 18 9 0,000 5,138E-03 0,01520771 ! endoderm development GO:0007492 12 9 0,000 5,138E-03 0,01518816 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 5,138E-03 0,01516867 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 5,138E-03 0,01514922 ! arginine catabolic process GO:0006527 10 9 0,000 5,138E-03 0,01512982 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 5,138E-03 0,01511048 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 5,138E-03 0,01509118 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 5,138E-03 0,01507193 ! phosphagen metabolic process GO:0006599 12 9 0,000 5,138E-03 0,01505273 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 5,138E-03 0,01503358 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 5,138E-03 0,01501448 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 5,138E-03 0,01499542 ! mannose metabolic process GO:0006013 9 9 0,000 5,138E-03 0,01497642 ! substrate-bound cell migration GO:0006929 10 9 0,000 5,138E-03 0,01495746 ! receptor clustering GO:0043113 15 9 0,000 5,138E-03 0,01493855 ! epithelial cell development GO:0002064 10 9 0,000 5,138E-03 0,01491969 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 5,138E-03 0,01490087 ! retinoic acid metabolic process GO:0042573 11 9 0,000 5,138E-03 0,01488211 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 5,138E-03 0,01486339 ! positive regulation of translational initiation GO:0045948 10 9 0,000 5,138E-03 0,01484471 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 5,138E-03 0,01482609 ! motor axon guidance GO:0008045 14 9 0,000 5,138E-03 0,01480751 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 5,138E-03 0,01478898 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 5,138E-03 0,01477049 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 5,138E-03 0,01475205 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 5,138E-03 0,01473366 ! blastoderm segmentation GO:0007350 11 9 0,000 5,138E-03 0,01471531 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 5,138E-03 0,014697 ! DNA ligation GO:0006266 14 9 0,000 5,138E-03 0,01467875 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 5,138E-03 0,01466054 ! response to amine stimulus GO:0014075 13 9 0,000 5,138E-03 0,01464237 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 5,138E-03 0,01462425 ! erythrocyte development GO:0048821 11 9 0,000 5,138E-03 0,01460617 ! renal water homeostasis GO:0003091 14 9 0,000 5,138E-03 0,01458814 ! postreplication repair GO:0006301 11 9 0,000 5,138E-03 0,01457015 ! mRNA cleavage GO:0006379 13 9 0,000 5,138E-03 0,01455221 ! hindbrain morphogenesis GO:0021575 12 9 0,000 5,138E-03 0,01453431 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 5,138E-03 0,01451645 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 5,138E-03 0,01449864 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 5,138E-03 0,01448087 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 5,138E-03 0,01446315 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 5,138E-03 0,01444547 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 5,138E-03 0,01442783 ! acid secretion GO:0046717 14 9 0,000 5,138E-03 0,01441023 ! musculoskeletal movement GO:0050881 11 9 0,000 5,138E-03 0,01439268 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 5,138E-03 0,01437517 ! methionine biosynthetic process GO:0009086 10 9 0,000 5,138E-03 0,01435771 ! purine base metabolic process GO:0006144 18 9 0,000 5,138E-03 0,01434028 ! oocyte differentiation GO:0009994 12 9 0,000 5,138E-03 0,0143229 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 5,138E-03 0,01430556 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 5,138E-03 0,01428826 ! spleen development GO:0048536 15 9 0,000 5,138E-03 0,014271 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 5,138E-03 0,01425379 ! anterior/posterior axis specification GO:0009948 11 9 0,000 5,138E-03 0,01423662 ! regulation of RNA splicing GO:0043484 14 9 0,000 5,138E-03 0,01421948 ! detection of calcium ion GO:0005513 13 9 0,000 5,138E-03 0,01420239 ! blastocyst formation GO:0001825 12 9 0,000 5,138E-03 0,01418534 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 5,138E-03 0,01416834 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 5,138E-03 0,01415137 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 5,138E-03 0,01413444 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 5,138E-03 0,01411755 ! regulation of amino acid transport GO:0051955 11 9 0,000 5,138E-03 0,01410071 ! positive regulation of amine transport GO:0051954 15 9 0,000 5,138E-03 0,0140839 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 5,138E-03 0,01406713 ! prepulse inhibition GO:0060134 14 9 0,000 5,138E-03 0,01405041 ! embryonic placenta development GO:0001892 12 9 0,000 5,138E-03 0,01403372 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 5,138E-03 0,01401707 ! insulin secretion GO:0030073 17 9 0,000 5,138E-03 0,01400046 ! sequestering of metal ion GO:0051238 11 9 0,000 5,138E-03 0,0139839 ! response to nicotine GO:0035094 16 9 0,000 5,138E-03 0,01396737 ! establishment of cell polarity GO:0030010 12 9 0,000 5,138E-03 0,01395088 ! nucleus localization GO:0051647 15 9 0,000 5,138E-03 0,01393442 ! regulation of synapse organization GO:0050807 12 9 0,000 5,138E-03 0,01391801 ! localization within membrane GO:0051668 15 9 0,000 5,138E-03 0,01390164 ! negative regulation of muscle development GO:0048635 12 10 0,000 5,707E-03 0,01542414 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 5,707E-03 0,01540604 ! neuron fate specification GO:0048665 11 10 0,000 5,707E-03 0,01538798 ! negative regulation of blood pressure GO:0045776 22 10 0,000 5,707E-03 0,01536996 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 5,707E-03 0,01535198 ! thyroid gland development GO:0030878 19 10 0,000 5,707E-03 0,01533405 ! regulation of B cell proliferation GO:0030888 15 10 0,000 5,707E-03 0,01531616 ! synapsis GO:0007129 13 10 0,000 5,707E-03 0,01529831 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 5,707E-03 0,0152805 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 5,707E-03 0,01526273 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 5,707E-03 0,015245 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 5,707E-03 0,01522732 ! sulfate transport GO:0008272 12 10 0,000 5,707E-03 0,01520967 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 5,707E-03 0,01519207 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 5,707E-03 0,0151745 ! androgen metabolic process GO:0008209 13 10 0,000 5,707E-03 0,01515698 ! phospholipid efflux GO:0033700 16 10 0,000 5,707E-03 0,0151395 ! hippocampus development GO:0021766 19 10 0,000 5,707E-03 0,01512206 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 5,707E-03 0,01510466 ! blood vessel remodeling GO:0001974 21 10 0,000 5,707E-03 0,01508729 ! positive regulation of heart contraction GO:0045823 14 10 0,000 5,707E-03 0,01506997 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 5,707E-03 0,01505269 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 5,707E-03 0,01503545 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 5,707E-03 0,01501824 ! pathogenesis GO:0009405 13 10 0,000 5,707E-03 0,01500108 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 5,707E-03 0,01498396 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 5,707E-03 0,01496687 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 5,707E-03 0,01494982 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 5,707E-03 0,01493282 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 5,707E-03 0,01491585 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 5,707E-03 0,01489892 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 5,707E-03 0,01488202 ! melanocyte differentiation GO:0030318 15 10 0,000 5,707E-03 0,01486517 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 5,707E-03 0,01484836 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 5,707E-03 0,01483158 ! reverse cholesterol transport GO:0043691 16 10 0,000 5,707E-03 0,01481484 ! response to X-ray GO:0010165 16 10 0,000 5,707E-03 0,01479814 ! B cell proliferation GO:0042100 14 10 0,000 5,707E-03 0,01478147 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 5,707E-03 0,01476484 ! regulation of sodium ion transport GO:0002028 15 10 0,000 5,707E-03 0,01474825 ! forebrain cell migration GO:0021885 17 10 0,000 5,707E-03 0,0147317 ! lipid digestion GO:0044241 15 10 0,000 5,707E-03 0,01471519 ! phagocytosis, engulfment GO:0006911 20 10 0,000 5,707E-03 0,01469871 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 5,707E-03 0,01468227 ! UV protection GO:0009650 14 10 0,000 5,707E-03 0,01466586 ! entry into host cell GO:0030260 20 10 0,000 5,707E-03 0,01464949 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 5,707E-03 0,01463316 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 5,707E-03 0,01461687 ! negative regulation of ossification GO:0030279 19 10 0,000 5,707E-03 0,01460061 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 5,707E-03 0,01458438 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 5,707E-03 0,0145682 ! regulation of bone resorption GO:0045124 24 10 0,000 5,707E-03 0,01455205 ! alpha-beta T cell activation GO:0046631 16 10 0,000 5,707E-03 0,01453593 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 5,707E-03 0,01451985 ! regulation of organ growth GO:0046620 11 10 0,000 5,707E-03 0,01450381 ! response to dsRNA GO:0043331 18 10 0,000 5,707E-03 0,0144878 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 5,707E-03 0,01447183 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 5,707E-03 0,01445589 ! embryonic axis specification GO:0000578 12 10 0,000 5,707E-03 0,01443998 ! regulation of B cell differentiation GO:0045577 16 10 0,000 5,707E-03 0,01442412 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 5,707E-03 0,01440828 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 5,707E-03 0,01439248 ! cranial nerve development GO:0021545 12 10 0,000 5,707E-03 0,01437672 ! fucose catabolic process GO:0019317 16 10 0,000 5,707E-03 0,01436099 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 5,707E-03 0,0143453 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 5,707E-03 0,01432964 ! protein sumoylation GO:0016925 12 10 0,000 5,707E-03 0,01431401 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 5,707E-03 0,01429842 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 5,707E-03 0,01428286 ! zymogen activation GO:0031638 14 10 0,000 5,707E-03 0,01426733 ! salivary gland development GO:0007431 22 10 0,000 5,707E-03 0,01425184 ! negative regulation of neurological system process GO:0031645 19 10 0,000 5,707E-03 0,01423638 ! glutathione biosynthetic process GO:0006750 11 10 0,000 5,707E-03 0,01422096 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 5,707E-03 0,01420557 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 5,707E-03 0,01419021 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 5,707E-03 0,01417489 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 5,707E-03 0,0141596 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 5,707E-03 0,01414434 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 5,707E-03 0,01412911 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 5,707E-03 0,01411392 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 5,707E-03 0,01409876 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 5,707E-03 0,01408363 ! detection of bacterium GO:0016045 10 10 0,000 5,707E-03 0,01406854 ! embryonic gut development GO:0048566 11 10 0,000 5,707E-03 0,01405348 ! activation of innate immune response GO:0002218 10 10 0,000 5,707E-03 0,01403844 GO:0002758|innate immune response-activating signal transduction, ! cardiac cell differentiation GO:0035051 16 10 0,000 5,707E-03 0,01402345 ! developmental induction GO:0031128 13 10 0,000 5,707E-03 0,01400848 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 5,707E-03 0,01399355 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 5,707E-03 0,01397864 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 5,707E-03 0,01396377 ! negative regulation of immune effector process GO:0002698 16 10 0,000 5,707E-03 0,01394893 ! rRNA transcription GO:0009303 17 11 0,000 6,276E-03 0,01532359 ! respiratory burst GO:0045730 14 11 0,000 6,276E-03 0,01530734 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 6,276E-03 0,01529113 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 6,276E-03 0,01527495 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 6,276E-03 0,0152588 ! virus-host interaction GO:0019048 17 11 0,000 6,276E-03 0,01524269 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 6,276E-03 0,01522661 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 6,276E-03 0,01521056 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 6,276E-03 0,01519455 ! Golgi vesicle budding GO:0048194 17 11 0,000 6,276E-03 0,01517858 ! RNA polyadenylation GO:0043631 19 11 0,000 6,276E-03 0,01516263 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 6,276E-03 0,01514672 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 6,276E-03 0,01513084 ! mating GO:0007618 14 11 0,000 6,276E-03 0,015115 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 6,276E-03 0,01509919 ! T cell proliferation GO:0042098 20 11 0,000 6,276E-03 0,01508341 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 6,276E-03 0,01506767 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 6,276E-03 0,01505196 ! bone resorption GO:0045453 16 11 0,000 6,276E-03 0,01503628 ! regulated secretory pathway GO:0045055 14 11 0,000 6,276E-03 0,01502063 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 6,276E-03 0,01500502 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 6,276E-03 0,01498943 ! regulation of mRNA processing GO:0050684 18 11 0,000 6,276E-03 0,01497389 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 6,276E-03 0,01495837 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 6,276E-03 0,01494288 ! syncytium formation GO:0006949 15 11 0,000 6,276E-03 0,01492743 ! plasma membrane organization GO:0007009 18 11 0,000 6,276E-03 0,01491201 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 6,276E-03 0,01489662 ! focal adhesion formation GO:0048041 24 11 0,000 6,276E-03 0,01488126 ! mitotic spindle organization GO:0007052 15 11 0,000 6,276E-03 0,01486594 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 6,276E-03 0,01485064 ! regulation of intracellular pH GO:0051453 17 11 0,000 6,276E-03 0,01483538 ! membrane protein proteolysis GO:0033619 18 11 0,000 6,276E-03 0,01482015 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 6,276E-03 0,01480495 ! adult heart development GO:0007512 11 11 0,000 6,276E-03 0,01478978 ! chondrocyte differentiation GO:0002062 17 11 0,000 6,276E-03 0,01477464 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 6,276E-03 0,01475954 ! temperature homeostasis GO:0001659 16 11 0,000 6,276E-03 0,01474446 ! L-glutamate transport GO:0015813 16 11 0,000 6,276E-03 0,01472941 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 6,276E-03 0,0147144 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 6,276E-03 0,01469941 ! protein targeting to peroxisome GO:0006625 20 11 0,000 6,276E-03 0,01468446 ! stem cell development GO:0048864 29 11 0,000 6,276E-03 0,01466954 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 6,276E-03 0,01465464 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 6,276E-03 0,01463978 ! regulation of phagocytosis GO:0050764 14 11 0,000 6,276E-03 0,01462495 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 6,276E-03 0,01461015 ! vasoconstriction GO:0042310 15 11 0,000 6,276E-03 0,01459537 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 6,276E-03 0,01458063 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 6,276E-03 0,01456592 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 6,276E-03 0,01455124 ! ribosome assembly GO:0042255 13 11 0,000 6,276E-03 0,01453658 ! nitric oxide metabolic process GO:0046209 14 11 0,000 6,276E-03 0,01452196 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 6,276E-03 0,01450736 ! chromatin silencing GO:0006342 19 11 0,000 6,276E-03 0,0144928 ! nucleosome positioning GO:0016584 13 11 0,000 6,276E-03 0,01447826 ! T cell homeostasis GO:0043029 20 11 0,000 6,276E-03 0,01446375 ! regulation of isotype switching GO:0045191 19 11 0,000 6,276E-03 0,01444927 ! regulation of leukocyte migration GO:0002685 24 11 0,000 6,276E-03 0,01443483 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 6,276E-03 0,0144204 ! protein-chromophore linkage GO:0018298 13 11 0,000 6,276E-03 0,01440601 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 6,276E-03 0,01439165 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 6,276E-03 0,01437732 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 6,276E-03 0,01436301 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 6,276E-03 0,01434873 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 6,276E-03 0,01433448 ! male genitalia development GO:0030539 13 11 0,000 6,276E-03 0,01432026 ! cholesterol efflux GO:0033344 19 11 0,000 6,276E-03 0,01430607 ! digestive tract morphogenesis GO:0048546 15 11 0,000 6,276E-03 0,01429191 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 6,276E-03 0,01427777 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 6,276E-03 0,01426366 ! negative regulation of glucose import GO:0046325 14 11 0,000 6,276E-03 0,01424958 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 6,276E-03 0,01423553 ! regulation of organic acid transport GO:0032890 17 11 0,000 6,276E-03 0,0142215 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 6,276E-03 0,01420751 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 6,276E-03 0,01419354 ! mRNA 3'-end processing GO:0031124 19 11 0,000 6,276E-03 0,01417959 ! lysogeny GO:0030069 18 11 0,000 6,276E-03 0,01416568 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 6,276E-03 0,01415179 ! acrosome reaction GO:0007340 13 11 0,000 6,276E-03 0,01413793 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 6,276E-03 0,0141241 ! lactation GO:0007595 20 12 0,000 6,845E-03 0,01538908 ! reproductive cellular process GO:0048610 14 12 0,000 6,845E-03 0,01537405 ! tRNA modification GO:0006400 14 12 0,000 6,845E-03 0,01535905 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 6,845E-03 0,01534408 ! positive regulation of blood pressure GO:0045777 16 12 0,000 6,845E-03 0,01532914 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 6,845E-03 0,01531423 ! 'de novo' protein folding GO:0006458 18 12 0,000 6,845E-03 0,01529935 ! dicarboxylic acid transport GO:0006835 22 12 0,000 6,845E-03 0,0152845 ! non-recombinational repair GO:0000726 19 12 0,000 6,845E-03 0,01526967 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 6,845E-03 0,01525487 ! peroxisomal transport GO:0043574 21 12 0,000 6,845E-03 0,01524011 ! cartilage condensation GO:0001502 18 12 0,000 6,845E-03 0,01522537 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 6,845E-03 0,01521066 ! cytokine biosynthetic process GO:0042089 16 12 0,000 6,845E-03 0,01519598 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 6,845E-03 0,01518132 ! heart looping GO:0001947 15 12 0,000 6,845E-03 0,0151667 ! palate development GO:0060021 15 12 0,000 6,845E-03 0,0151521 ! positive regulation of cell growth GO:0030307 16 12 0,000 6,845E-03 0,01513753 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 6,845E-03 0,01512299 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 6,845E-03 0,01510847 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 6,845E-03 0,01509399 ! arginine metabolic process GO:0006525 13 12 0,000 6,845E-03 0,01507953 ! glycoprotein catabolic process GO:0006516 19 12 0,000 6,845E-03 0,0150651 ! methionine metabolic process GO:0006555 13 12 0,000 6,845E-03 0,0150507 ! tyrosine metabolic process GO:0006570 14 12 0,000 6,845E-03 0,01503632 ! Golgi organization GO:0007030 18 12 0,000 6,845E-03 0,01502198 ! cell-cell junction assembly GO:0007043 18 12 0,000 6,845E-03 0,01500766 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 6,845E-03 0,01499336 ! monoamine transport GO:0015844 13 12 0,000 6,845E-03 0,0149791 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 6,845E-03 0,01496486 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 6,845E-03 0,01495065 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 6,845E-03 0,01493646 ! L-amino acid transport GO:0015807 20 12 0,000 6,845E-03 0,0149223 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 6,845E-03 0,01490817 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 6,845E-03 0,01489407 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 6,845E-03 0,01487999 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 6,845E-03 0,01486594 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 6,845E-03 0,01485192 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 6,845E-03 0,01483792 ! cerebellum development GO:0021549 13 12 0,000 6,845E-03 0,01482395 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 6,845E-03 0,01481 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 6,845E-03 0,01479608 ! histone acetylation GO:0016573 23 12 0,000 6,845E-03 0,01478219 ! histone methylation GO:0016571 15 12 0,000 6,845E-03 0,01476832 ! autonomic nervous system development GO:0048483 23 12 0,000 6,845E-03 0,01475448 ! gland morphogenesis GO:0022612 23 12 0,000 6,845E-03 0,01474067 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 6,845E-03 0,01472688 ! peptidyl-lysine modification GO:0018205 18 12 0,000 6,845E-03 0,01471311 ! negative regulation of protein secretion GO:0050709 20 12 0,000 6,845E-03 0,01469937 ! response to gamma radiation GO:0010332 20 12 0,000 6,845E-03 0,01468566 ! regulation of epidermis development GO:0045682 17 12 0,000 6,845E-03 0,01467198 ! intestinal absorption GO:0050892 19 12 0,000 6,845E-03 0,01465832 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 6,845E-03 0,01464468 ! cAMP biosynthetic process GO:0006171 20 12 0,000 6,845E-03 0,01463107 ! regulation of mRNA stability GO:0043488 27 12 0,000 6,845E-03 0,01461748 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 6,845E-03 0,01460392 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 6,845E-03 0,01459039 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 6,845E-03 0,01457688 ! RNA 3'-end processing GO:0031123 20 12 0,000 6,845E-03 0,0145634 ! microspike assembly GO:0030035 23 12 0,000 6,845E-03 0,01454994 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 6,845E-03 0,0145365 ! response to cold GO:0009409 14 12 0,000 6,845E-03 0,01452309 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 7,413E-03 0,0157148 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 7,413E-03 0,01570033 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 7,413E-03 0,01568589 ! cGMP metabolic process GO:0046068 16 13 0,000 7,413E-03 0,01567147 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 7,413E-03 0,01565708 ! water transport GO:0006833 17 13 0,000 7,413E-03 0,01564272 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 7,413E-03 0,01562838 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 7,413E-03 0,01561407 ! lipid localization GO:0010876 24 13 0,000 7,413E-03 0,01559978 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 7,413E-03 0,01558552 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 7,413E-03 0,01557129 ! organelle fusion GO:0048284 28 13 0,000 7,413E-03 0,01555708 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 7,413E-03 0,0155429 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 7,413E-03 0,01552874 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 7,413E-03 0,01551461 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 7,413E-03 0,01550051 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 7,413E-03 0,01548643 ! response to hexose stimulus GO:0009746 19 13 0,000 7,413E-03 0,01547238 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 7,413E-03 0,01545835 ! glutamate metabolic process GO:0006536 18 13 0,000 7,413E-03 0,01544435 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 7,413E-03 0,01543037 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 7,413E-03 0,01541642 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 7,413E-03 0,01540249 ! NAD metabolic process GO:0019674 21 13 0,000 7,413E-03 0,01538859 ! exocrine system development GO:0035272 27 13 0,000 7,413E-03 0,01537472 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 7,413E-03 0,01536087 ! bone mineralization GO:0030282 15 13 0,000 7,413E-03 0,01534704 ! regulation of exocytosis GO:0017157 17 13 0,000 7,413E-03 0,01533324 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 7,413E-03 0,01531946 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 7,413E-03 0,01530571 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 7,413E-03 0,01529198 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 7,413E-03 0,01527828 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 7,413E-03 0,0152646 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 7,413E-03 0,01525095 ! genitalia development GO:0048806 15 13 0,000 7,413E-03 0,01523732 ! regulation of cellular pH GO:0030641 20 13 0,000 7,413E-03 0,01522372 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 7,413E-03 0,01521014 ! cellular pigmentation GO:0033059 24 13 0,000 7,413E-03 0,01519658 ! tissue regeneration GO:0042246 21 13 0,000 7,413E-03 0,01518305 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 7,413E-03 0,01516954 ! cofactor transport GO:0051181 19 13 0,000 7,413E-03 0,01515605 ! NADP metabolic process GO:0006739 18 13 0,000 7,413E-03 0,01514259 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 7,413E-03 0,01512916 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 7,413E-03 0,01511575 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 7,413E-03 0,01510236 ! gas transport GO:0015669 18 13 0,000 7,413E-03 0,01508899 ! regulation of RNA stability GO:0043487 28 13 0,000 7,413E-03 0,01507565 ! heme biosynthetic process GO:0006783 20 13 0,000 7,413E-03 0,01506233 ! regulation of axon extension GO:0030516 23 13 0,000 7,413E-03 0,01504904 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 7,413E-03 0,01503577 ! lymphocyte homeostasis GO:0002260 24 13 0,000 7,413E-03 0,01502252 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 7,413E-03 0,0150093 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 7,413E-03 0,0149961 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 7,413E-03 0,01498292 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 7,413E-03 0,01496976 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 7,981E-03 0,016103 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 7,981E-03 0,01608889 ! superoxide anion generation GO:0042554 18 14 0,000 7,981E-03 0,0160748 ! neuron maturation GO:0042551 21 14 0,000 7,981E-03 0,01606073 ! regulation of S phase GO:0033261 18 14 0,000 7,981E-03 0,0160467 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 7,981E-03 0,01603268 ! myotube differentiation GO:0014902 21 14 0,000 7,981E-03 0,01601869 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 7,981E-03 0,01600472 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 7,981E-03 0,01599078 ! heterophilic cell adhesion GO:0007157 29 14 0,000 7,981E-03 0,01597687 ! inositol metabolic process GO:0006020 20 14 0,000 7,981E-03 0,01596297 ! aminoglycan catabolic process GO:0006026 18 14 0,000 7,981E-03 0,0159491 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 7,981E-03 0,01593526 ! retina development in camera-type eye GO:0060041 18 14 0,000 7,981E-03 0,01592144 ! cardiac muscle contraction GO:0060048 23 14 0,000 7,981E-03 0,01590764 ! gene silencing by RNA GO:0031047 20 14 0,000 7,981E-03 0,01589387 ! response to cAMP GO:0051591 19 14 0,000 7,981E-03 0,01588012 ! limbic system development GO:0021761 25 14 0,000 7,981E-03 0,0158664 ! startle response GO:0001964 21 14 0,000 7,981E-03 0,01585269 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 7,981E-03 0,01583902 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 7,981E-03 0,01582536 ! activation of MAPKK activity GO:0000186 21 14 0,000 7,981E-03 0,01581173 ! regulation of defense response to virus GO:0050688 24 14 0,000 7,981E-03 0,01579812 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 7,981E-03 0,01578454 ! epidermis morphogenesis GO:0048730 29 14 0,000 7,981E-03 0,01577098 ! glycine metabolic process GO:0006544 22 14 0,000 7,981E-03 0,01575744 ! pituitary gland development GO:0021983 23 14 0,000 7,981E-03 0,01574393 ! cellular response to starvation GO:0009267 21 14 0,000 7,981E-03 0,01573044 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 7,981E-03 0,01571697 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 7,981E-03 0,01570352 ! regulation of heart rate GO:0002027 23 14 0,000 7,981E-03 0,0156901 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 7,981E-03 0,0156767 ! negative regulation of caspase activity GO:0043154 20 14 0,000 7,981E-03 0,01566333 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 7,981E-03 0,01564997 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 7,981E-03 0,01563664 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 7,981E-03 0,01562334 ! G1/S transition checkpoint GO:0031575 33 14 0,000 7,981E-03 0,01561005 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 7,981E-03 0,01559679 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 7,981E-03 0,01558355 ! axon cargo transport GO:0008088 27 14 0,000 7,981E-03 0,01557033 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 7,981E-03 0,01555713 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 7,981E-03 0,01554396 ! DNA unwinding during replication GO:0006268 21 14 0,000 7,981E-03 0,01553081 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 7,981E-03 0,01551768 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 7,981E-03 0,01550458 ! mRNA splice site selection GO:0006376 26 14 0,000 7,981E-03 0,01549149 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 7,981E-03 0,01547843 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 7,981E-03 0,01546539 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 7,981E-03 0,01545237 ! sphingolipid catabolic process GO:0030149 23 14 0,000 7,981E-03 0,01543938 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 7,981E-03 0,0154264 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 7,981E-03 0,01541345 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 7,981E-03 0,01540052 ! muscle maintenance GO:0046716 19 14 0,000 7,981E-03 0,01538761 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 7,981E-03 0,01537472 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 7,981E-03 0,01536186 ! regulation of ATPase activity GO:0043462 18 14 0,000 7,981E-03 0,01534901 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 7,981E-03 0,01533619 ! cell killing GO:0001906 20 14 0,000 7,981E-03 0,01532339 ! release of cytochrome c from mitochondria GO:0001836 23 14 0,000 7,981E-03 0,01531061 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 7,981E-03 0,01529785 ! cilium assembly GO:0042384 20 14 0,000 7,981E-03 0,01528511 ! peptide hormone secretion GO:0030072 23 14 0,000 7,981E-03 0,0152724 ! positive regulation of cell size GO:0045793 20 15 0,000 8,549E-03 0,01634547 ! metencephalon development GO:0022037 19 15 0,000 8,549E-03 0,0163319 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 8,549E-03 0,01631834 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 8,549E-03 0,01630481 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 8,549E-03 0,0162913 ! skin development GO:0043588 25 15 0,000 8,549E-03 0,01627782 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 8,549E-03 0,01626435 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 8,549E-03 0,01625091 ! lipid phosphorylation GO:0046834 23 15 0,000 8,549E-03 0,01623749 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 8,549E-03 0,0162241 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 8,549E-03 0,01621072 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 8,549E-03 0,01619737 ! bile acid metabolic process GO:0008206 22 15 0,000 8,549E-03 0,01618404 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 8,549E-03 0,01617073 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 8,549E-03 0,01615744 ! adult walking behavior GO:0007628 25 15 0,000 8,549E-03 0,01614417 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 8,549E-03 0,01613093 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 8,549E-03 0,01611771 ! myoblast differentiation GO:0045445 27 15 0,000 8,549E-03 0,01610451 ! centrosome cycle GO:0007098 16 15 0,000 8,549E-03 0,01609133 ! positive regulation of proteolysis GO:0045862 19 15 0,000 8,549E-03 0,01607817 ! regulation of survival gene product expression GO:0045884 20 15 0,000 8,549E-03 0,01606504 ! cardiac muscle tissue development GO:0048738 23 15 0,000 8,549E-03 0,01605192 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 8,549E-03 0,01603883 ! cerebral cortex development GO:0021987 29 15 0,000 8,549E-03 0,01602576 ! response to osmotic stress GO:0006970 22 15 0,000 8,549E-03 0,01601271 ! vesicle coating GO:0006901 25 15 0,000 8,549E-03 0,01599968 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 8,549E-03 0,01598667 ! DNA integration GO:0015074 22 15 0,000 8,549E-03 0,01597368 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 8,549E-03 0,01596072 ! peptide secretion GO:0002790 27 15 0,000 8,549E-03 0,01594777 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 8,549E-03 0,01593485 ! regulation of vasodilation GO:0042312 24 15 0,000 8,549E-03 0,01592195 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 8,549E-03 0,01590906 ! neuron recognition GO:0008038 22 15 0,000 8,549E-03 0,0158962 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 8,549E-03 0,01588336 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 8,549E-03 0,01587054 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 8,549E-03 0,01585774 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 8,549E-03 0,01584497 ! peptide biosynthetic process GO:0043043 19 15 0,000 8,549E-03 0,01583221 ! biomineral formation GO:0031214 18 15 0,000 8,549E-03 0,01581947 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 8,549E-03 0,01580676 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 8,549E-03 0,01579406 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 8,549E-03 0,01578138 ! dopamine metabolic process GO:0042417 30 15 0,000 8,549E-03 0,01576873 ! organic cation transport GO:0015695 19 15 0,000 8,549E-03 0,01575609 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 8,549E-03 0,01574348 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 8,549E-03 0,01573088 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 8,549E-03 0,01571831 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 8,549E-03 0,01570575 ! defense response to virus GO:0051607 27 15 0,000 8,549E-03 0,01569322 ! peptide hormone processing GO:0016486 19 15 0,000 8,549E-03 0,0156807 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 8,549E-03 0,01566821 ! protein secretion GO:0009306 27 16 0,000 9,117E-03 0,01669515 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 9,117E-03 0,01668187 ! hormone secretion GO:0046879 25 16 0,000 9,117E-03 0,01666861 ! bone remodeling GO:0046849 24 16 0,000 9,117E-03 0,01665537 ! endothelial cell migration GO:0043542 22 16 0,000 9,117E-03 0,01664215 ! protein amino acid deacetylation GO:0006476 20 16 0,000 9,117E-03 0,01662896 ! protein amino acid acetylation GO:0006473 28 16 0,000 9,117E-03 0,01661578 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 9,117E-03 0,01660262 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 9,117E-03 0,01658949 ! glial cell development GO:0021782 24 16 0,000 9,117E-03 0,01657638 ! patterning of blood vessels GO:0001569 24 16 0,000 9,117E-03 0,01656328 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 9,117E-03 0,01655021 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 9,117E-03 0,01653716 ! protein polyubiquitination GO:0000209 26 16 0,000 9,117E-03 0,01652412 ! complement activation, alternative pathway GO:0006957 16 16 0,000 9,117E-03 0,01651111 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 9,117E-03 0,01649812 ! fructose metabolic process GO:0006000 20 16 0,000 9,117E-03 0,01648515 ! regulation of protein binding GO:0043393 27 16 0,000 9,117E-03 0,0164722 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 9,117E-03 0,01645927 ! protein export from nucleus GO:0006611 24 16 0,000 9,117E-03 0,01644636 ! negative regulation of immune response GO:0050777 28 16 0,000 9,117E-03 0,01643348 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 9,117E-03 0,01642061 ! DNA replication initiation GO:0006270 25 16 0,000 9,117E-03 0,01640776 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 9,117E-03 0,01639493 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 9,117E-03 0,01638212 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 9,117E-03 0,01636933 ! diencephalon development GO:0021536 25 16 0,000 9,117E-03 0,01635656 ! oogenesis GO:0048477 23 16 0,000 9,117E-03 0,01634381 ! neural crest cell migration GO:0001755 24 16 0,000 9,117E-03 0,01633109 ! G1 phase GO:0051318 27 16 0,000 9,117E-03 0,01631838 ! neutrophil chemotaxis GO:0030593 21 16 0,000 9,117E-03 0,01630569 ! protein localization in mitochondrion GO:0070585 22 16 0,000 9,117E-03 0,01629302 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 9,117E-03 0,01628037 ! steroid catabolic process GO:0006706 22 16 0,000 9,117E-03 0,01626774 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 9,117E-03 0,01625513 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 9,117E-03 0,01624254 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 9,117E-03 0,01622996 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 9,117E-03 0,01621741 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 9,117E-03 0,01620488 ! sperm-egg recognition GO:0035036 16 16 0,000 9,117E-03 0,01619237 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 9,117E-03 0,01617987 ! nerve development GO:0021675 18 16 0,000 9,117E-03 0,0161674 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 9,117E-03 0,01615494 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 9,117E-03 0,01614251 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 9,684E-03 0,01713381 ! positive regulation of cell killing GO:0031343 24 17 0,000 9,684E-03 0,01712064 ! negative regulation of defense response GO:0031348 19 17 0,000 9,684E-03 0,01710749 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 9,684E-03 0,01709436 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 9,684E-03 0,01708125 ! glycerol metabolic process GO:0006071 20 17 0,000 9,684E-03 0,01706816 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 9,684E-03 0,01705509 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 9,684E-03 0,01704205 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 9,684E-03 0,01702902 ! signal complex assembly GO:0007172 29 17 0,000 9,684E-03 0,01701601 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 9,684E-03 0,01700302 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 9,684E-03 0,01699005 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 9,684E-03 0,0169771 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 9,684E-03 0,01696417 ! forelimb morphogenesis GO:0035136 19 17 0,000 9,684E-03 0,01695126 ! memory GO:0007613 25 17 0,000 9,684E-03 0,01693837 ! keratinization GO:0031424 17 17 0,000 9,684E-03 0,0169255 ! negative regulation of ion transport GO:0043271 20 17 0,000 9,684E-03 0,01691264 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 9,684E-03 0,01689981 ! retinoid metabolic process GO:0001523 22 17 0,000 9,684E-03 0,016887 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 9,684E-03 0,01687421 ! inactivation of MAPK activity GO:0000188 27 17 0,000 9,684E-03 0,01686143 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 9,684E-03 0,01684868 ! DNA duplex unwinding GO:0032508 25 17 0,000 9,684E-03 0,01683594 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 9,684E-03 0,01682323 ! cell-substrate junction assembly GO:0007044 39 17 0,000 9,684E-03 0,01681053 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 0,000 9,684E-03 0,01679785 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 9,684E-03 0,01678519 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 9,684E-03 0,01677255 ! membrane budding GO:0006900 29 17 0,000 9,684E-03 0,01675993 ! heme metabolic process GO:0042168 27 17 0,000 9,684E-03 0,01674733 ! actin filament bundle formation GO:0051017 26 17 0,000 9,684E-03 0,01673475 ! neuromuscular junction development GO:0007528 23 17 0,000 9,684E-03 0,01672219 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 9,684E-03 0,01670964 ! body fluid secretion GO:0007589 27 17 0,000 9,684E-03 0,01669712 ! stem cell differentiation GO:0048863 36 17 0,000 9,684E-03 0,01668461 ! nucleobase metabolic process GO:0009112 31 17 0,000 9,684E-03 0,01667212 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 9,684E-03 0,01665965 ! behavioral interaction between organisms GO:0051705 25 17 0,000 9,684E-03 0,0166472 ! sensory perception of pain GO:0019233 23 17 0,000 9,684E-03 0,01663477 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 9,684E-03 0,01662235 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 9,684E-03 0,01660996 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 9,684E-03 0,01659758 ! synaptogenesis GO:0007416 24 17 0,000 9,684E-03 0,01658522 ! peptidyl-serine modification GO:0018209 27 17 0,000 9,684E-03 0,01657288 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 9,684E-03 0,01656056 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 9,684E-03 0,01654826 ! cell-cell junction organization GO:0045216 25 17 0,000 9,684E-03 0,01653597 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 9,684E-03 0,0165237 ! proximal/distal pattern formation GO:0009954 25 17 0,000 9,684E-03 0,01651146 ! aromatic compound catabolic process GO:0019439 22 17 0,000 9,684E-03 0,01649922 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 9,684E-03 0,01648701 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 9,684E-03 0,01647482 ! negative regulation of coagulation GO:0050819 23 17 0,000 9,684E-03 0,01646264 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,01025136 0,01741368 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,01025136 0,01740083 ! positive regulation of translation GO:0045727 28 18 0,000 0,01025136 0,01738799 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,01025136 0,01737518 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,01025136 0,01736239 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,01025136 0,01734961 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,01025136 0,01733685 ! cAMP metabolic process GO:0046058 33 18 0,000 0,01025136 0,01732411 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,01025136 0,01731139 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,01025136 0,01729869 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,01025136 0,01728601 ! axis specification GO:0009798 26 18 0,000 0,01025136 0,01727335 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,01025136 0,0172607 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,01025136 0,01724808 ! pancreas development GO:0031016 26 18 0,000 0,01025136 0,01723547 ! apoptotic mitochondrial changes GO:0008637 29 18 0,000 0,01025136 0,01722288 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,01025136 0,01721031 ! glutamine metabolic process GO:0006541 23 18 0,000 0,01025136 0,01719775 ! response to retinoic acid GO:0032526 25 18 0,000 0,01025136 0,01718522 ! pigmentation during development GO:0048066 31 18 0,000 0,01025136 0,0171727 ! central nervous system neuron development GO:0021954 30 18 0,000 0,01025136 0,0171602 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,01025136 0,01714772 ! fucose metabolic process GO:0006004 26 18 0,000 0,01025136 0,01713526 ! response to fungus GO:0009620 19 18 0,000 0,01025136 0,01712282 ! peptide cross-linking GO:0018149 31 18 0,000 0,01025136 0,01711039 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,01025136 0,01709798 ! heart process GO:0003015 27 18 0,000 0,01025136 0,01708559 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,01025136 0,01707322 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,01025136 0,01706087 ! visual learning GO:0008542 35 18 0,000 0,01025136 0,01704853 ! somitogenesis GO:0001756 24 18 0,000 0,01025136 0,01703621 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,01025136 0,01702391 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,01025136 0,01701163 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,01025136 0,01699936 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,01025136 0,01698712 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,01025136 0,01697489 ! vitamin transport GO:0051180 24 18 0,000 0,01025136 0,01696268 ! hormone transport GO:0009914 27 18 0,000 0,01025136 0,01695048 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,01025136 0,0169383 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,01025136 0,01692614 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,01025136 0,016914 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,01025136 0,01690188 ! cell-cell recognition GO:0009988 20 18 0,000 0,01025136 0,01688977 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,01025136 0,01687768 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,01025136 0,01686561 ! regulation of glucose import GO:0046324 21 18 0,000 0,01025136 0,01685355 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,01025136 0,01684151 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,01025136 0,01682949 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,01025136 0,01681749 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,01025136 0,0168055 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,01081809 0,01772195 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,01081809 0,01770933 ! positive regulation of fibroblast proliferation GO:0048146 27 19 0,000 0,01081809 0,01769674 ! positive regulation of ossification GO:0045778 30 19 0,000 0,01081809 0,01768416 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,01081809 0,0176716 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,01081809 0,01765906 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,01081809 0,01764653 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,01081809 0,01763403 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,01081809 0,01762154 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,01081809 0,01760907 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,01081809 0,01759661 ! regeneration GO:0031099 32 19 0,000 0,01081809 0,01758418 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,01081809 0,01757176 ! response to alkaloid GO:0043279 32 19 0,000 0,01081809 0,01755936 ! sensory perception of taste GO:0050909 23 19 0,000 0,01081809 0,01754698 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,01081809 0,01753461 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 0,000 0,01081809 0,01752226 ! smooth muscle contraction GO:0006939 36 19 0,000 0,01081809 0,01750993 ! peroxisome organization GO:0007031 29 19 0,000 0,01081809 0,01749762 ! digestive system process GO:0022600 30 19 0,000 0,01081809 0,01748532 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,01081809 0,01747304 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,01081809 0,01746078 ! response to vitamin A GO:0033189 26 19 0,000 0,01081809 0,01744854 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,01081809 0,01743631 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,01081809 0,0174241 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,01081809 0,01741191 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,01081809 0,01739973 ! response to starvation GO:0042594 30 19 0,000 0,01081809 0,01738757 ! sex determination GO:0007530 29 19 0,000 0,01081809 0,01737543 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,01081809 0,0173633 ! plasma membrane fusion GO:0045026 23 19 0,000 0,01081809 0,01735119 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,01081809 0,0173391 ! cytolysis GO:0019835 20 19 0,000 0,01081809 0,01732703 ! renal system process GO:0003014 35 19 0,000 0,01081809 0,01731497 ! vasodilation GO:0042311 33 19 0,000 0,01081809 0,01730293 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,01081809 0,01729091 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,01081809 0,0172789 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,01081809 0,01726691 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,01081809 0,01725493 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,01081809 0,01724298 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,01081809 0,01723103 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,01081809 0,01721911 ! sarcomere organization GO:0045214 23 19 0,000 0,01081809 0,0172072 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,01081809 0,01719531 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,01081809 0,01718343 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,01081809 0,01717158 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,01081809 0,01715973 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,01081809 0,01714791 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,01081809 0,0171361 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,01081809 0,0171243 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,01081809 0,01711253 ! protein stabilization GO:0050821 26 19 0,000 0,01081809 0,01710076 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,01138454 0,01798382 ! iron ion transport GO:0006826 37 20 0,000 0,01138454 0,01797147 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,01138454 0,01795915 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,01138454 0,01794684 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,01138454 0,01793454 ! response to vitamin GO:0033273 29 20 0,000 0,01138454 0,01792227 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,01138454 0,01791001 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,01138454 0,01789777 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,01138454 0,01788554 ! spinal cord development GO:0021510 31 20 0,000 0,01138454 0,01787333 ! response to ethanol GO:0045471 37 20 0,000 0,01138454 0,01786114 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,01138454 0,01784897 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 0,000 0,01138454 0,01783681 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,01138454 0,01782467 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,01138454 0,01781254 ! chromosome condensation GO:0030261 31 20 0,000 0,01138454 0,01780043 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,01138454 0,01778834 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,01138454 0,01777626 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,01138454 0,0177642 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,01138454 0,01775216 ! pallium development GO:0021543 38 20 0,000 0,01138454 0,01774013 ! DNA modification GO:0006304 28 20 0,000 0,01138454 0,01772812 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,01138454 0,01771613 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,01138454 0,01770415 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,01138454 0,01769219 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,01138454 0,01768024 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,01138454 0,01766831 ! positive regulation of B cell activation GO:0050871 31 20 0,000 0,01138454 0,0176564 ! collagen catabolic process GO:0030574 25 20 0,000 0,01138454 0,0176445 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,01138454 0,01763262 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,01138454 0,01762075 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,01138454 0,0176089 ! alditol metabolic process GO:0019400 24 20 0,000 0,01138454 0,01759707 ! actin filament-based movement GO:0030048 34 20 0,000 0,01138454 0,01758525 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,01195069 0,01844737 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,01195069 0,018435 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,01195069 0,01842264 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,01195069 0,01841031 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 0,000 0,01195069 0,01839798 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,01195069 0,01838568 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,01195069 0,01837339 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,01195069 0,01836111 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,01195069 0,01834886 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,01195069 0,01833662 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,01195069 0,01832439 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,01195069 0,01831218 ! protein amino acid acylation GO:0043543 37 21 0,000 0,01195069 0,01829999 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,01195069 0,01828781 ! vesicle docking GO:0048278 27 21 0,000 0,01195069 0,01827566 ! phototransduction GO:0007602 25 21 0,000 0,01195069 0,01826351 ! dendrite development GO:0016358 35 21 0,000 0,01195069 0,01825139 ! visual behavior GO:0007632 39 21 0,000 0,01195069 0,01823927 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,01195069 0,01822718 ! ovarian follicle development GO:0001541 30 21 0,000 0,01195069 0,0182151 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,01195069 0,01820304 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,01195069 0,01819099 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,01195069 0,01817896 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,01195069 0,01816694 ! cell aging GO:0007569 32 21 0,000 0,01195069 0,01815494 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,01195069 0,01814296 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,01195069 0,01813099 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,01195069 0,01811904 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,01195069 0,01810711 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,01195069 0,01809518 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,01195069 0,01808328 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,01195069 0,01807139 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,01195069 0,01805952 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,01195069 0,01804766 ! fatty acid transport GO:0015908 30 21 0,000 0,01195069 0,01803582 ! immunoglobulin production GO:0002377 33 21 0,000 0,01195069 0,01802399 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,01195069 0,01801218 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,01195069 0,01800038 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,01195069 0,0179886 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,01195069 0,01797684 ! cellular response to extracellular stimulus GO:0031668 32 21 0,000 0,01195069 0,01796509 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,01195069 0,01795335 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,01195069 0,01794164 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,01195069 0,01792993 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,01195069 0,01791824 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,01195069 0,01790657 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,01195069 0,01789491 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,01195069 0,01788327 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,01195069 0,01787164 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,01195069 0,01786003 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,01195069 0,01784843 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,01251655 0,01868142 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,01251655 0,0186693 ! regulation of fibroblast proliferation GO:0048145 35 22 0,000 0,01251655 0,0186572 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,01251655 0,01864512 ! viral genome replication GO:0019079 29 22 0,000 0,01251655 0,01863305 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,01251655 0,018621 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,01251655 0,01860896 ! leukocyte adhesion GO:0007159 38 22 0,000 0,01251655 0,01859694 ! molting cycle process GO:0022404 40 22 0,000 0,01251655 0,01858494 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,01251655 0,01857295 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,01251655 0,01856097 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,01251655 0,01854901 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,01251655 0,01853707 ! vasculogenesis GO:0001570 33 22 0,000 0,01251655 0,01852514 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,01251655 0,01851323 GO:0051297|centrosome organization, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,01251655 0,01850133 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,01251655 0,01848944 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,01251655 0,01847758 ! lysosome organization GO:0007040 37 22 0,000 0,01251655 0,01846573 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,01251655 0,01845389 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,01251655 0,01844207 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,01251655 0,01843026 ! regulation of behavior GO:0050795 38 22 0,000 0,01251655 0,01841847 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,01251655 0,01840669 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,01251655 0,01839493 ! membrane depolarization GO:0051899 35 22 0,000 0,01251655 0,01838318 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,01251655 0,01837145 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,01251655 0,01835974 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,01251655 0,01834803 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,01251655 0,01833635 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,01251655 0,01832468 ! blastocyst development GO:0001824 37 22 0,000 0,01251655 0,01831302 ! neural tube closure GO:0001843 33 22 0,000 0,01251655 0,01830138 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,01251655 0,01828975 ! protein tetramerization GO:0051262 39 22 0,000 0,01251655 0,01827814 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,01308212 0,01909193 ! neuron fate commitment GO:0048663 32 23 0,000 0,01308212 0,01907982 ! embryonic pattern specification GO:0009880 31 23 0,000 0,01308212 0,01906773 ! myelination GO:0042552 35 23 0,000 0,01308212 0,01905565 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,01308212 0,01904359 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,01308212 0,01903155 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,01308212 0,01901952 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,01308212 0,0190075 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,01308212 0,0189955 ! vesicle targeting GO:0006903 32 23 0,000 0,01308212 0,01898352 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,01308212 0,01897155 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,01308212 0,01895959 ! osteoblast differentiation GO:0001649 40 23 0,000 0,01308212 0,01894765 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,01308212 0,01893573 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,01308212 0,01892382 ! interaction with host GO:0051701 37 23 0,000 0,01308212 0,01891193 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,01308212 0,01890005 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,01308212 0,01888818 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,01308212 0,01887633 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,01308212 0,0188645 ! negative regulation of phosphorylation GO:0042326 41 23 0,000 0,01308212 0,01885268 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,01308212 0,01884087 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,01308212 0,01882908 ! cell fate determination GO:0001709 45 23 0,000 0,01308212 0,01881731 ! pentose metabolic process GO:0019321 31 23 0,000 0,01308212 0,01880555 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,01308212 0,0187938 ! spermatid development GO:0007286 33 23 0,000 0,01308212 0,01878207 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,01308212 0,01877035 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,01308212 0,01875865 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,01308212 0,01874696 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,01308212 0,01873529 ! telomere organization GO:0032200 32 23 0,000 0,01308212 0,01872363 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,01308212 0,01871199 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,01308212 0,01870036 ! regulation of amine transport GO:0051952 38 23 0,000 0,01308212 0,01868874 ! liver development GO:0001889 40 23 0,000 0,01308212 0,01867714 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,0136474 0,01947209 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,0136474 0,01946002 ! initiation of viral infection GO:0019059 42 24 0,000 0,0136474 0,01944796 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,0136474 0,01943592 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,0136474 0,01942389 ! superoxide metabolic process GO:0006801 32 24 0,000 0,0136474 0,01941188 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,0136474 0,01939988 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! insulin receptor signaling pathway GO:0008286 40 24 0,000 0,0136474 0,0193879 ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,0136474 0,01937593 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,0136474 0,01936398 ! sperm motility GO:0030317 27 24 0,000 0,0136474 0,01935204 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,0136474 0,01934012 ! vacuole organization GO:0007033 39 24 0,000 0,0136474 0,01932821 ! receptor metabolic process GO:0043112 37 24 0,000 0,0136474 0,01931632 ! neural crest cell development GO:0014032 39 24 0,000 0,0136474 0,01930444 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,0136474 0,01929257 ! primary neural tube formation GO:0014020 35 24 0,000 0,0136474 0,01928072 ! negative regulation of cell development GO:0010721 56 24 0,000 0,0136474 0,01926888 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,0136474 0,01925706 ! base-excision repair GO:0006284 31 24 0,000 0,0136474 0,01924526 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,0136474 0,01923346 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,0136474 0,01922169 ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,0136474 0,01920992 ! glutathione metabolic process GO:0006749 29 24 0,000 0,0136474 0,01919817 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,0136474 0,01918644 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,0136474 0,01917472 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,0136474 0,01916301 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,01421238 0,01994416 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,01421238 0,019932 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,01421238 0,01991985 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,01421238 0,01990772 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,01421238 0,01989561 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,01421238 0,0198835 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 0,000 0,01421238 0,01987142 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,01421238 0,01985934 ! peptide transport GO:0015833 43 25 0,000 0,01421238 0,01984729 ! male gonad development GO:0008584 33 25 0,000 0,01421238 0,01983524 ! iron ion homeostasis GO:0055072 39 25 0,000 0,01421238 0,01982321 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,01421238 0,0198112 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,01421238 0,0197992 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,01421238 0,01978722 ! phospholipid transport GO:0015914 35 25 0,000 0,01421238 0,01977525 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,01421238 0,01976329 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,01421238 0,01975135 ! detection of light stimulus GO:0009583 30 25 0,000 0,01421238 0,01973942 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,01421238 0,01972751 GO:0045840|positive regulation of mitosis, ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,01421238 0,01971561 ! leukocyte proliferation GO:0070661 39 25 0,000 0,01421238 0,01970373 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,01421238 0,01969186 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,01477708 0,02046194 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,01477708 0,02044963 ! translational initiation GO:0006413 43 26 0,000 0,01477708 0,02043733 ! regulation of pH GO:0006885 36 26 0,000 0,01477708 0,02042505 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 0,000 0,01477708 0,02041278 ! circadian rhythm GO:0007623 42 26 0,000 0,01477708 0,02040053 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,01477708 0,02038829 ! post-embryonic development GO:0009791 42 26 0,000 0,01477708 0,02037607 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,01477708 0,02036386 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,01477708 0,02035166 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,01477708 0,02033948 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,01477708 0,02032732 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,01477708 0,02031517 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,01477708 0,02030303 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,01477708 0,02029091 ! regulation of coagulation GO:0050818 39 26 0,000 0,01477708 0,02027881 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,01534148 0,02104079 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,01534148 0,02102825 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,01534148 0,02101573 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,01534148 0,02100322 ! membrane docking GO:0022406 39 27 0,000 0,01534148 0,02099072 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,01534148 0,02097824 ! catechol metabolic process GO:0009712 43 27 0,000 0,01534148 0,02096578 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,01534148 0,02095333 ! acute-phase response GO:0006953 42 27 0,000 0,01534148 0,02094089 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,01534148 0,02092847 ! myofibril assembly GO:0030239 36 27 0,000 0,01534148 0,02091607 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,01534148 0,02090368 ! response to ionizing radiation GO:0010212 47 27 0,000 0,01534148 0,0208913 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,01534148 0,02087894 ! natural killer cell activation GO:0030101 35 27 0,000 0,01534148 0,02086659 ! lipid oxidation GO:0034440 38 27 0,000 0,01534148 0,02085426 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,01534148 0,02084194 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,01534148 0,02082964 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,01534148 0,02081735 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,01534148 0,02080507 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,01534148 0,02079281 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,01534148 0,02078057 ! gene silencing GO:0016458 41 27 0,000 0,01534148 0,02076834 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,01590559 0,02151933 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,01590559 0,02150668 ! phenol metabolic process GO:0018958 44 28 0,000 0,01590559 0,02149405 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,01590559 0,02148142 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,01590559 0,02146882 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,01590559 0,02145623 ! cell junction assembly GO:0034329 56 28 0,000 0,01590559 0,02144365 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,01590559 0,02143109 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,01590559 0,02141854 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,01590559 0,02140601 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,01590559 0,02139349 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,01590559 0,02138098 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,01590559 0,0213685 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,01590559 0,02135602 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,01590559 0,02134356 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,01590559 0,02133112 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,01590559 0,02131869 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,01590559 0,02130627 ! mesoderm formation GO:0001707 46 28 0,000 0,01590559 0,02129387 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,01590559 0,02128148 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,01590559 0,02126911 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,01590559 0,02125675 ! ensheathment of neurons GO:0007272 43 28 0,000 0,01590559 0,0212444 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,01590559 0,02123208 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,01590559 0,02121976 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,01590559 0,02120746 ! neural tube formation GO:0001841 41 28 0,000 0,01590559 0,02119517 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,01590559 0,0211829 ! placenta development GO:0001890 37 28 0,000 0,01590559 0,02117064 ! regulation of B cell activation GO:0050864 42 28 0,000 0,01590559 0,0211584 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,01646942 0,02189575 ! regulation of innate immune response GO:0045088 38 29 0,000 0,01646942 0,02188311 ! ovulation cycle process GO:0022602 41 29 0,000 0,01646942 0,02187047 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,01646942 0,02185785 ! protein targeting to membrane GO:0006612 53 29 0,000 0,01646942 0,02184525 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,01646942 0,02183265 ! mismatch repair GO:0006298 34 29 0,000 0,01646942 0,02182008 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,01646942 0,02180752 ! muscle cell development GO:0055001 38 29 0,000 0,01646942 0,02179497 ! formation of primary germ layer GO:0001704 48 29 0,000 0,01646942 0,02178244 ! telencephalon development GO:0021537 52 29 0,000 0,01646942 0,02176992 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,01646942 0,02175741 ! eye morphogenesis GO:0048592 51 29 0,000 0,01646942 0,02174492 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,01646942 0,02173245 ! tissue homeostasis GO:0001894 42 29 0,000 0,01646942 0,02171999 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,01703295 0,0224503 ! collagen metabolic process GO:0032963 40 30 0,000 0,01703295 0,02243744 ! organic anion transport GO:0015711 51 30 0,000 0,01703295 0,0224246 ! cholesterol transport GO:0030301 46 30 0,000 0,01703295 0,02241177 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,01703295 0,02239896 ! spliceosome assembly GO:0000245 49 30 0,000 0,01703295 0,02238616 ! spindle organization GO:0007051 37 30 0,000 0,01703295 0,02237337 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,01703295 0,0223606 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,01703295 0,02234785 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,01703295 0,02233511 ! ceramide metabolic process GO:0006672 43 30 0,000 0,01703295 0,02232238 ! ovulation cycle GO:0042698 43 30 0,000 0,01703295 0,02230967 ! hindbrain development GO:0030902 45 30 0,000 0,01703295 0,02229697 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,01703295 0,02228429 ! adult locomotory behavior GO:0008344 47 30 0,000 0,01703295 0,02227162 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,01703295 0,02225896 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,01703295 0,02224632 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,01703295 0,0222337 ! response to heat GO:0009408 41 30 0,000 0,01703295 0,02222109 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,01703295 0,02220849 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,01703295 0,02219591 ! negative regulation of secretion GO:0051048 49 31 0,000 0,01759619 0,02291689 ! mammary gland development GO:0030879 57 31 0,000 0,01759619 0,02290392 ! glial cell differentiation GO:0010001 55 31 0,000 0,01759619 0,02289097 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,01759619 0,02287803 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,01759619 0,0228651 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,01759619 0,02285219 ! odontogenesis GO:0042476 50 31 0,000 0,01759619 0,02283929 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,01759619 0,02282641 ! segmentation GO:0035282 41 31 0,000 0,01759619 0,02281355 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,01759619 0,02280069 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,01759619 0,02278785 ! metanephros development GO:0001656 58 31 0,000 0,01759619 0,02277503 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,01759619 0,02276222 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,01759619 0,02274943 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,01759619 0,02273665 ! cell fate specification GO:0001708 37 31 0,000 0,01759619 0,02272388 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,01759619 0,02271113 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,01759619 0,02269839 ! RNA modification GO:0009451 40 31 0,000 0,01759619 0,02268567 ! regulation of muscle development GO:0048634 48 32 0,000 0,01815914 0,02339833 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,01815914 0,02338523 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,01815914 0,02337214 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,01815914 0,02335907 ! meiosis I GO:0007127 52 32 0,000 0,01815914 0,02334601 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,01815914 0,02333297 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,01815914 0,02331994 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,01815914 0,02330693 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,01815914 0,02329393 ! peripheral nervous system development GO:0007422 53 32 0,000 0,01815914 0,02328094 ! regulation of protein stability GO:0031647 48 32 0,000 0,01815914 0,02326797 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,01815914 0,02325502 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,01815914 0,02324208 ! cytokine production GO:0001816 44 32 0,000 0,01815914 0,02322915 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,01815914 0,02321624 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,01815914 0,02320334 ! vesicle localization GO:0051648 47 32 0,000 0,01815914 0,02319046 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,0187218 0,02389574 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,0187218 0,02388249 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,0187218 0,02386925 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,0187218 0,02385603 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,0187218 0,02384282 ! sister chromatid segregation GO:0000819 46 33 0,000 0,0187218 0,02382962 ! ear morphogenesis GO:0042471 42 33 0,000 0,0187218 0,02381644 ! actomyosin structure organization GO:0031032 43 33 0,000 0,0187218 0,02380328 ! cell junction organization GO:0034330 63 33 0,000 0,0187218 0,02379013 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,0187218 0,02377699 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,0187218 0,02376387 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,0187218 0,02375076 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 0,000 0,0187218 0,02373767 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,0187218 0,02372459 ! female gonad development GO:0008585 49 33 0,000 0,0187218 0,02371153 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,0187218 0,02369848 ! positive regulation of cell development GO:0010720 54 33 0,000 0,0187218 0,02368544 ! lipid homeostasis GO:0055088 55 33 0,000 0,0187218 0,02367242 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,0187218 0,02365941 ! regulation of proteolysis GO:0030162 50 33 0,000 0,0187218 0,02364642 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,0187218 0,02363344 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,0187218 0,02362048 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,0187218 0,02360753 ! cytokinesis GO:0000910 52 33 0,000 0,0187218 0,02359459 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,0187218 0,02358167 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,01928417 0,02427673 ! mRNA catabolic process GO:0006402 48 34 0,000 0,01928417 0,02426345 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,01928417 0,02425018 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,01928417 0,02423693 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,01928417 0,02422369 ! feeding behavior GO:0007631 45 34 0,000 0,01928417 0,02421047 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,01928417 0,02419726 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,01928417 0,02418407 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,01928417 0,02417089 ! neuron migration GO:0001764 46 34 0,000 0,01928417 0,02415772 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,01928417 0,02414457 ! female gamete generation GO:0007292 43 34 0,000 0,01928417 0,02413144 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,01928417 0,02411831 ! polyol metabolic process GO:0019751 44 34 0,000 0,01928417 0,02410521 ! aerobic respiration GO:0009060 47 34 0,000 0,01928417 0,02409211 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,01928417 0,02407903 ! cellular response to insulin stimulus GO:0032869 52 34 0,000 0,01928417 0,02406597 ! embryonic organ development GO:0048568 45 34 0,000 0,01928417 0,02405292 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,01928417 0,02403988 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,01984624 0,02472717 ! Notch signaling pathway GO:0007219 56 35 0,000 0,01984624 0,02471379 ! regulation of intracellular protein transport GO:0033157 59 35 0,000 0,01984624 0,02470041 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,01984624 0,02468705 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,01984624 0,02467371 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,01984624 0,02466038 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,01984624 0,02464706 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,01984624 0,02463376 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,01984624 0,02462048 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,01984624 0,0246072 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,01984624 0,02459395 ! glycogen metabolic process GO:0005977 48 35 0,000 0,01984624 0,0245807 ! pigment metabolic process GO:0042440 61 35 0,000 0,01984624 0,02456747 ! positive regulation of leukocyte proliferation GO:0070665 50 35 0,000 0,01984624 0,02455426 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! protein homooligomerization GO:0051260 52 35 0,000 0,01984624 0,02454106 ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,02040803 0,02522218 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 0,000 0,02040803 0,02520863 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,02040803 0,0251951 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,02040803 0,02518159 ! negative regulation of binding GO:0051100 58 36 0,000 0,02040803 0,02516808 ! organic ether metabolic process GO:0018904 46 36 0,000 0,02040803 0,0251546 ! tissue remodeling GO:0048771 62 36 0,000 0,02040803 0,02514112 ! neural tube development GO:0021915 50 36 0,000 0,02040803 0,02512766 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,02040803 0,02511422 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,02040803 0,02510079 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,02040803 0,02508737 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,02040803 0,02507397 ! glucan metabolic process GO:0044042 49 36 0,000 0,02040803 0,02506059 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,02096953 0,02573635 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,02096953 0,02572263 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,02096953 0,02570892 ! learning GO:0007612 67 37 0,000 0,02096953 0,02569522 ! ion transmembrane transport GO:0034220 56 37 0,000 0,02096953 0,02568154 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,02096953 0,02566787 ! regulation of protein secretion GO:0050708 51 37 0,000 0,02096953 0,02565422 ! amino acid activation GO:0043038 52 37 0,000 0,02096953 0,02564058 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,02096953 0,02562695 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,02153074 0,02629884 ! gliogenesis GO:0042063 71 38 0,000 0,02153074 0,02628488 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,02153074 0,02627093 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,02153074 0,026257 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,02153074 0,02624309 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,02153074 0,02622919 ! phagocytosis GO:0006909 60 38 0,000 0,02153074 0,0262153 ! mesenchymal cell development GO:0014031 64 38 0,000 0,02153074 0,02620143 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 0,000 0,02153074 0,02618758 ! maintenance of location in cell GO:0051651 69 38 0,000 0,02153074 0,02617374 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,02209166 0,02684143 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,02209166 0,02682726 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,02209166 0,0268131 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,02209166 0,02679896 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,02209166 0,02678483 ! regulation of epithelial cell proliferation GO:0050678 71 39 0,000 0,02209166 0,02677072 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,02209166 0,02675662 ! male sex differentiation GO:0046661 53 39 0,000 0,02209166 0,02674254 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,02209166 0,02672847 ! chromatin remodeling GO:0006338 68 39 0,000 0,02209166 0,02671442 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,02209166 0,02670038 ! JNK cascade GO:0007254 54 39 0,000 0,02209166 0,02668636 ! developmental growth GO:0048589 62 39 0,000 0,02209166 0,02667235 ! cell growth GO:0016049 61 39 0,000 0,02209166 0,02665836 ! synapse organization GO:0050808 55 39 0,000 0,02209166 0,02664438 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,02265229 0,02730622 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,02265229 0,02729192 ! regulation of tube size GO:0035150 60 40 0,000 0,02265229 0,02727763 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,02265229 0,02726336 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,02265229 0,0272491 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,02265229 0,02723485 ! peptide metabolic process GO:0006518 56 40 0,000 0,02265229 0,02722063 ! induction of apoptosis by intracellular signals GO:0008629 67 40 0,000 0,02265229 0,02720641 ! inner ear development GO:0048839 57 40 0,000 0,02265229 0,02719221 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,02265229 0,02717803 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,02265229 0,02716386 ! double-strand break repair GO:0006302 67 40 0,000 0,02265229 0,0271497 ! B cell differentiation GO:0030183 62 40 0,000 0,02265229 0,02713556 ! epidermal cell differentiation GO:0009913 53 40 0,000 0,02265229 0,02712143 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,02265229 0,02710732 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,02265229 0,02709323 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,02265229 0,02707915 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,02321264 0,02773458 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,02321264 0,02772018 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,02321264 0,02770579 ! glucose transport GO:0015758 52 41 0,000 0,02321264 0,02769142 ! endosome transport GO:0016197 71 41 0,000 0,02321264 0,02767707 ! striated muscle contraction GO:0006941 62 41 0,000 0,02321264 0,02766273 ! positive regulation of DNA binding GO:0043388 57 41 0,000 0,02321264 0,0276484 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,02321264 0,02763409 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,02321264 0,02761979 ! biopolymer methylation GO:0043414 62 41 0,000 0,02321264 0,02760551 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,02321264 0,02759125 ! mitochondrial transport GO:0006839 60 42 0,000 0,02377269 0,02824235 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,02377269 0,02822777 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 0,000 0,02377269 0,0282132 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,02377269 0,02819865 ! cellular component disassembly GO:0022411 64 42 0,000 0,02377269 0,02818411 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,02377269 0,02816959 ! hexose transport GO:0008645 54 42 0,000 0,02377269 0,02815509 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,02377269 0,0281406 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,02377269 0,02812612 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,02377269 0,02811166 ! excretion GO:0007588 63 42 0,000 0,02377269 0,02809722 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,02377269 0,02808279 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,02377269 0,02806837 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,02377269 0,02805397 ! regulation of cell shape GO:0008360 78 42 0,000 0,02377269 0,02803958 ! positive regulation of binding GO:0051099 59 43 0,000 0,02433245 0,0286851 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,02433245 0,02867041 ! leukocyte migration GO:0050900 60 43 0,000 0,02433245 0,02865573 ! neuromuscular process GO:0050905 79 43 0,000 0,02433245 0,02864106 ! activation of caspase activity GO:0006919 65 43 0,000 0,02433245 0,02862641 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,02433245 0,02861178 ! tRNA processing GO:0008033 49 43 0,000 0,02433245 0,02859716 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,02433245 0,02858255 ! vesicle organization GO:0016050 79 43 0,000 0,02433245 0,02856796 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,02433245 0,02855339 ! methylation GO:0032259 64 43 0,000 0,02433245 0,02853883 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,02489193 0,02918014 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,02489193 0,02916527 ! glycolysis GO:0006096 53 44 0,000 0,02489193 0,02915042 ! regulation of action potential GO:0001508 71 44 0,000 0,02489193 0,02913559 ! regulation of ion transport GO:0043269 57 44 0,000 0,02489193 0,02912077 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,02489193 0,02910596 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,02489193 0,02909117 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,02489193 0,0290764 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,02489193 0,02906164 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,02489193 0,02904689 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,02489193 0,02903217 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,02489193 0,02901745 ! regulation of mast cell proliferation GO:0070666 64 44 0,000 0,02489193 0,02900275 ! RNA catabolic process GO:0006401 64 45 0,000 0,02545111 0,02963927 ! positive regulation of defense response GO:0031349 59 45 0,000 0,02545111 0,02962427 ! regulation of translational initiation GO:0006446 64 45 0,000 0,02545111 0,02960929 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,02545111 0,02959432 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,02545111 0,02957936 ! cell recognition GO:0008037 58 45 0,000 0,02545111 0,02956442 ! cell maturation GO:0048469 60 45 0,000 0,02545111 0,0295495 ! protein amino acid autophosphorylation GO:0046777 80 45 0,000 0,02545111 0,02953459 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,02601001 0,03016794 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,02601001 0,03015273 ! cell redox homeostasis GO:0045454 63 46 0,000 0,02601001 0,03013754 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,02601001 0,03012237 ! regulation of ossification GO:0030278 71 46 0,000 0,02601001 0,03010721 ! histone modification GO:0016570 68 46 0,000 0,02601001 0,03009206 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,02601001 0,03007693 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,02656862 0,03070745 ! viral infectious cycle GO:0019058 71 47 0,000 0,02656862 0,03069202 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,02656862 0,03067662 ! endocrine system development GO:0035270 83 47 0,000 0,02656862 0,03066122 ! covalent chromatin modification GO:0016569 75 47 0,000 0,02656862 0,03064585 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,02656862 0,03063049 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,02656862 0,03061514 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,02656862 0,03059981 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,02656862 0,03058449 ! regulation of leukocyte proliferation GO:0070663 71 47 0,000 0,02656862 0,03056919 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,02656862 0,03055391 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,02656862 0,03053864 ! chloride transport GO:0006821 67 48 0,000 0,02712694 0,03116481 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,02712694 0,03114925 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 0,000 0,02712694 0,03113371 ! response to temperature stimulus GO:0009266 62 48 0,000 0,02712694 0,03111818 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,02712694 0,03110267 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,02712694 0,03108717 ! gastrulation GO:0007369 73 48 0,000 0,02712694 0,03107169 ! heart morphogenesis GO:0003007 65 48 0,000 0,02712694 0,03105623 ! regulation of DNA replication GO:0006275 75 48 0,000 0,02712694 0,03104077 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,02712694 0,03102534 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,02712694 0,03100992 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,02712694 0,03099451 ! regulation of endocytosis GO:0030100 63 48 0,000 0,02712694 0,03097912 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,02712694 0,03096375 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,02712694 0,03094839 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,02768497 0,03156938 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,02768497 0,03155373 ! sensory perception of smell GO:0007608 61 49 0,000 0,02768497 0,0315381 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,02768497 0,03152249 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,02768497 0,03150689 ! RNA elongation GO:0006354 62 49 0,000 0,02768497 0,03149131 ! regulation of intracellular transport GO:0032386 78 49 0,000 0,02768497 0,03147574 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,02768497 0,03146019 ! germ cell development GO:0007281 68 49 0,000 0,02768497 0,03144466 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,02768497 0,03142914 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,02768497 0,03141363 ! cartilage development GO:0051216 70 49 0,000 0,02768497 0,03139814 ! maintenance of location GO:0051235 84 49 0,000 0,02768497 0,03138267 ! regulation of actin filament length GO:0030832 72 50 0,000 0,02824271 0,03199913 ! ear development GO:0043583 72 50 0,000 0,02824271 0,03198338 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,02824271 0,03196764 ! membrane fusion GO:0006944 80 50 0,000 0,02824271 0,03195191 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,02824271 0,03193621 ! lipid modification GO:0030258 73 50 0,000 0,02824271 0,03192051 ! positive regulation of growth GO:0045927 67 50 0,000 0,02824271 0,03190483 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,02824271 0,03188917 ! proton transport GO:0015992 75 50 0,000 0,02824271 0,03187352 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,02824271 0,03185789 ! positive regulation of secretion GO:0051047 71 51 0,000 0,02880017 0,03247078 ! hydrogen transport GO:0006818 77 51 0,000 0,02880017 0,03245487 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,02880017 0,03243898 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 0,000 0,02880017 0,0324231 ! positive regulation of cell migration GO:0030335 92 51 0,000 0,02880017 0,03240724 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,02880017 0,03239139 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,02880017 0,03237556 ! adult behavior GO:0030534 80 51 0,000 0,02880017 0,03235974 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,02880017 0,03234394 ! transition metal ion transport GO:0000041 74 52 0,000 0,02935734 0,03295358 ! regulation of cellular component size GO:0032535 74 52 0,000 0,02935734 0,0329375 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,02935734 0,03292144 ! aging GO:0007568 79 52 0,000 0,02935734 0,0329054 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,02935734 0,03288937 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,02935734 0,03287336 ! establishment of organelle localization GO:0051656 85 52 0,000 0,02935734 0,03285736 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,02991422 0,03346435 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,02991422 0,03344808 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,02991422 0,03343183 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,02991422 0,03341559 ! kidney development GO:0001822 90 53 0,000 0,02991422 0,03339937 ! single fertilization GO:0007338 59 53 0,000 0,02991422 0,03338316 ! cell projection assembly GO:0030031 76 53 0,000 0,02991422 0,03336697 ! amino acid transport GO:0006865 84 54 0,000 0,03047081 0,03397134 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,03047081 0,03395488 ! regulation of mitosis GO:0007088 84 54 0,000 0,03047081 0,03393843 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,03047081 0,03392201 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,03047081 0,0339056 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,03047081 0,0338892 ! DNA catabolic process GO:0006308 67 54 0,000 0,03047081 0,03387282 ! detection of external stimulus GO:0009581 66 54 0,000 0,03047081 0,03385646 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,03047081 0,03384011 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,03047081 0,03382378 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,03047081 0,03380746 ! exocytosis GO:0006887 74 55 0,000 0,03102712 0,03440808 ! mesoderm development GO:0007498 76 55 0,000 0,03102712 0,0343915 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,03102712 0,03437494 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,03102712 0,03435839 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,03158313 0,03495727 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,03158313 0,03494046 ! positive regulation of cell motion GO:0051272 99 56 0,000 0,03158313 0,03492366 ! negative regulation of protein kinase activity GO:0006469 99 57 0,000 0,03213887 0,03552109 ! carbohydrate transport GO:0008643 74 57 0,000 0,03213887 0,03550403 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,03213887 0,03548699 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 0,000 0,03213887 0,03546996 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,03213887 0,03545295 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,03213887 0,03543595 ! camera-type eye development GO:0043010 88 57 0,000 0,03213887 0,03541897 ! secondary metabolic process GO:0019748 84 57 0,000 0,03213887 0,03540201 ! developmental maturation GO:0021700 75 57 0,000 0,03213887 0,03538506 ! gonad development GO:0008406 79 57 0,000 0,03213887 0,03536813 ! negative regulation of kinase activity GO:0033673 100 58 0,000 0,03269431 0,03596218 ! viral reproductive process GO:0022415 87 58 0,000 0,03269431 0,03594499 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,03269431 0,03592781 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,03269431 0,03591066 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,03269431 0,03589351 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,03324947 0,03648558 ! activation of MAPK activity GO:0000187 84 59 0,000 0,03324947 0,03646818 ! lung development GO:0030324 94 59 0,000 0,03324947 0,0364508 ! actin filament organization GO:0007015 95 59 0,000 0,03324947 0,03643343 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,03324947 0,03641608 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,03324947 0,03639875 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,03380434 0,03698857 ! phosphoinositide metabolic process GO:0030384 87 60 0,000 0,03380434 0,03697098 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,03380434 0,03695341 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,03380434 0,03693586 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,03380434 0,03691832 ! regulation of heart contraction GO:0008016 91 60 0,000 0,03380434 0,0369008 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,03380434 0,03688329 ! fertilization GO:0009566 68 60 0,000 0,03380434 0,0368658 ! regulation of homeostatic process GO:0032844 105 60 0,000 0,03380434 0,03684833 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,03435892 0,03743511 ! meiosis GO:0007126 96 61 0,000 0,03435892 0,03741739 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 114 61 0,000 0,03435892 0,03739968 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,03435892 0,03738199 ! urogenital system development GO:0001655 101 61 0,000 0,03435892 0,03736431 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,03435892 0,03734665 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,03435892 0,03732901 ! extracellular matrix organization GO:0030198 103 61 0,000 0,03435892 0,03731139 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,03435892 0,03729378 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! negative regulation of transferase activity GO:0051348 105 61 0,000 0,03435892 0,03727619 ! amine catabolic process GO:0009310 90 62 0,000 0,03491322 0,03785969 ! neurotransmitter transport GO:0006836 81 62 0,000 0,03491322 0,03784185 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,03491322 0,03782402 ! negative regulation of cell growth GO:0030308 106 62 0,000 0,03491322 0,03780622 ! respiratory tube development GO:0030323 99 62 0,000 0,03491322 0,03778842 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,03491322 0,03777065 ! meiotic cell cycle GO:0051321 97 62 0,000 0,03491322 0,03775289 ! organelle localization GO:0051640 96 62 0,000 0,03491322 0,03773515 ! regulation of transcription factor activity GO:0051090 97 63 0,000 0,03546723 0,03831594 GO:0090046|regulation of transcription regulator activity, ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,03546723 0,03829795 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 0,000 0,03546723 0,03827997 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 0,000 0,03546723 0,03826202 ! viral reproduction GO:0016032 92 63 0,000 0,03546723 0,03824408 ! regulation of lipase activity GO:0060191 109 63 0,000 0,03546723 0,03822616 ! negative regulation of cell size GO:0045792 108 64 0,000 0,03602095 0,03880477 ! appendage morphogenesis GO:0035107 93 64 0,000 0,03602095 0,03878661 GO:0035108|limb morphogenesis, ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,03602095 0,03876846 ! hexose catabolic process GO:0019320 82 64 0,000 0,03602095 0,03875032 ! respiratory system development GO:0060541 100 64 0,000 0,03602095 0,03873221 ! adaptive immune response GO:0002250 94 64 0,000 0,03602095 0,03871411 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 90 65 0,000 0,03657439 0,03929057 ! regulation of caspase activity GO:0043281 97 65 0,000 0,03657439 0,03927222 ! appendage development GO:0048736 94 65 0,000 0,03657439 0,0392539 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 0,000 0,03657439 0,03923559 ! defense response to bacterium GO:0042742 73 65 0,000 0,03657439 0,0392173 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,03657439 0,03919902 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,03657439 0,03918076 ! activation of immune response GO:0002253 83 65 0,000 0,03657439 0,03916252 ! protein oligomerization GO:0051259 100 65 0,000 0,03657439 0,0391443 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,03712754 0,03971784 ! antigen processing and presentation GO:0019882 96 66 0,000 0,03712754 0,03969937 ! axon guidance GO:0007411 99 66 0,000 0,03712754 0,03968093 ! regulation of immune effector process GO:0002697 101 66 0,000 0,03712754 0,03966249 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,03768041 0,04023442 ! regulation of endopeptidase activity GO:0052548 99 67 0,000 0,03768041 0,04021575 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,03768041 0,0401971 ! acute inflammatory response GO:0002526 92 68 0,000 0,03823299 0,04076768 ! learning or memory GO:0007611 123 68 0,000 0,03823299 0,04074879 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,03823299 0,04072991 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,03823299 0,04071106 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,03823299 0,04069222 ! rhythmic process GO:0048511 105 68 0,000 0,03823299 0,0406734 ! inorganic anion transport GO:0015698 93 68 0,000 0,03823299 0,04065459 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,03878529 0,04122281 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,03878529 0,04120377 ! response to drug GO:0042493 108 69 0,000 0,03878529 0,04118475 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,0393373 0,04175163 ! humoral immune response GO:0006959 86 70 0,000 0,0393373 0,04173237 ! eye development GO:0001654 111 70 0,000 0,0393373 0,04171313 ! amine transport GO:0015837 101 70 0,000 0,0393373 0,04169391 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,0393373 0,0416747 ! regulation of catabolic process GO:0009894 106 70 0,000 0,0393373 0,04165552 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,03988902 0,04222032 ! muscle cell differentiation GO:0042692 104 71 0,000 0,03988902 0,0422009 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,03988902 0,04218149 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,03988902 0,04216211 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,03988902 0,04214274 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,03988902 0,04212339 ! regulation of peptidase activity GO:0052547 106 72 0,000 0,04044046 0,04268612 ! response to hypoxia GO:0001666 132 72 0,000 0,04044046 0,04266654 ! negative regulation of organelle organization GO:0010639 115 72 0,000 0,04044046 0,04264698 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,04044046 0,04262743 ! negative regulation of transport GO:0051051 116 73 0,000 0,04099161 0,0431886 ! regulation of blood pressure GO:0008217 107 73 0,000 0,04099161 0,04316883 ! tube morphogenesis GO:0035239 118 73 0,000 0,04099161 0,04314907 ! mitochondrion organization GO:0007005 104 73 0,000 0,04099161 0,04312933 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,04099161 0,04310961 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,04099161 0,04308991 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,04154248 0,04364902 ! response to oxygen levels GO:0070482 137 74 0,000 0,04154248 0,04362909 ! digestion GO:0007586 97 74 0,000 0,04154248 0,04360918 ! protein import into nucleus GO:0006606 118 74 0,000 0,04154248 0,04358929 ! cellular response to hormone stimulus GO:0032870 109 74 0,000 0,04154248 0,04356941 ! positive regulation of lymphocyte activation GO:0051251 108 74 0,000 0,04154248 0,04354955 ! blood coagulation GO:0007596 116 75 0,000 0,04209307 0,04410663 GO:0050817|coagulation, ! negative regulation of growth GO:0045926 123 75 0,000 0,04209307 0,04408655 ! response to nutrient GO:0007584 104 75 0,000 0,04209307 0,04406648 ! nuclear import GO:0051170 121 75 0,000 0,04209307 0,04404643 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,04209307 0,0440264 ! amine biosynthetic process GO:0009309 97 76 0,000 0,04264337 0,0445817 ! tRNA metabolic process GO:0006399 95 76 0,000 0,04264337 0,04456145 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,04264337 0,04454121 ! regulation of protein transport GO:0051223 114 76 0,000 0,04264337 0,04452099 GO:0070201|regulation of establishment of protein localization, ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,04319338 0,04507477 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,04319338 0,04505432 ! regulation of DNA binding GO:0051101 119 77 0,000 0,04319338 0,0450339 ! gland development GO:0048732 148 77 0,000 0,04319338 0,04501349 ! sex differentiation GO:0007548 105 77 0,000 0,04319338 0,04499311 ! protein ubiquitination GO:0016567 125 77 0,000 0,04319338 0,04497274 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,04319338 0,04495239 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,04319338 0,04493206 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,04319338 0,04491175 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,04374311 0,04546279 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,04374311 0,04544226 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,04429256 0,04599228 ! cellular respiration GO:0045333 107 79 0,000 0,04429256 0,04597152 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,04429256 0,04595079 ! T cell activation GO:0042110 134 79 0,000 0,04429256 0,04593007 ! regulation of lyase activity GO:0051339 133 79 0,000 0,04429256 0,04590937 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,04429256 0,04588869 ! chromatin assembly GO:0031497 102 80 0,000 0,04484172 0,04643672 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,04484172 0,04641583 ! protein localization in nucleus GO:0034504 133 80 0,000 0,04484172 0,04639495 ! forebrain development GO:0030900 131 80 0,000 0,04484172 0,04637408 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,0453906 0,04692062 ! hemostasis GO:0007599 125 81 0,000 0,0453906 0,04689954 ! mRNA transport GO:0051028 121 81 0,000 0,0453906 0,04687848 ! regulation of cell cycle process GO:0010564 122 81 0,000 0,0453906 0,04685744 ! regulation of neurological system process GO:0031644 122 81 0,000 0,0453906 0,04683642 ! vitamin metabolic process GO:0006766 103 81 0,000 0,0453906 0,04681542 ! positive regulation of cell activation GO:0050867 120 81 0,000 0,0453906 0,04679444 GO:0002696|positive regulation of leukocyte activation, ! ossification GO:0001503 134 82 0,000 0,0459392 0,04733878 GO:0060348|bone development, ! detection of stimulus GO:0051606 108 82 0,000 0,0459392 0,04731758 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,04648751 0,04786091 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,04648751 0,04783949 ! regulation of defense response GO:0031347 117 84 0,000 0,04703553 0,04838181 ! microtubule cytoskeleton organization GO:0000226 120 84 0,000 0,04703553 0,04836018 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,04703553 0,04833857 ! sterol metabolic process GO:0016125 120 84 0,000 0,04703553 0,04831699 ! regulation of DNA metabolic process GO:0051052 135 85 0,000 0,04758328 0,04885783 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,04758328 0,04883603 ! rRNA metabolic process GO:0016072 107 85 0,000 0,04758328 0,04881425 GO:0006364|rRNA processing, ! positive regulation of MAP kinase activity GO:0043406 121 85 0,000 0,04758328 0,04879248 ! transcription initiation GO:0006352 118 85 0,000 0,04758328 0,04877074 ! anterior/posterior pattern formation GO:0009952 124 85 0,000 0,04758328 0,04874902 ! regulation of protein localization GO:0032880 132 85 0,000 0,04758328 0,04872731 ! regulation of membrane potential GO:0042391 128 85 0,000 0,04758328 0,04870563 ! negative regulation of multicellular organismal process GO:0051241 133 85 0,000 0,04758328 0,04868396 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,04813074 0,04922219 ! cell cycle arrest GO:0007050 150 86 0,000 0,04813074 0,04920031 ! nucleosome organization GO:0034728 114 87 0,000 0,04867792 0,04973754 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,04867792 0,04971546 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,04867792 0,04969339 ! skeletal muscle tissue development GO:0007519 123 87 0,000 0,04867792 0,04967134 GO:0060538|skeletal muscle organ development, ! female pregnancy GO:0007565 130 87 0,000 0,04867792 0,04964932 ! Wnt receptor signaling pathway GO:0016055 130 87 0,000 0,04867792 0,04962731 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,04922481 0,05016263 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,04922481 0,05014042 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,04922481 0,05011822 GO:0016054|organic acid catabolic process, ! protein processing GO:0016485 114 88 0,000 0,04922481 0,05009605 ! regulation of neurogenesis GO:0050767 153 89 0,000 0,04977142 0,05062993 ! reproductive developmental process GO:0003006 127 89 0,000 0,04977142 0,05060755 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,04977142 0,05058518 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,04977142 0,05056284 ! regulation of T cell activation GO:0050863 128 89 0,000 0,04977142 0,05054052 ! leukocyte differentiation GO:0002521 143 90 0,000 0,05031775 0,05107274 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,05031775 0,05105021 ! hormone metabolic process GO:0042445 121 90 0,000 0,05031775 0,0510277 ! ATP metabolic process GO:0046034 137 91 0,000 0,05086379 0,05155872 ! response to virus GO:0009615 122 91 0,000 0,05086379 0,051536 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,05140956 0,05206604 ! glycerophospholipid metabolic process GO:0006650 130 92 0,000 0,05140956 0,05204313 ! cell fate commitment GO:0045165 141 92 0,000 0,05140956 0,05202023 ! positive regulation of immune response GO:0050778 121 92 0,000 0,05140956 0,05199735 ! DNA recombination GO:0006310 146 92 0,000 0,05140956 0,0519745 ! sulfur metabolic process GO:0006790 118 92 0,000 0,05140956 0,05195166 ! peptidyl-amino acid modification GO:0018193 147 93 0,000 0,05195504 0,05247984 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,05195504 0,0524568 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,05195504 0,05243378 ! electron transport chain GO:0022900 123 94 0,000 0,05250024 0,05296076 ! response to oxidative stress GO:0006979 141 94 0,000 0,05250024 0,05293755 ! regulation of binding GO:0051098 151 95 0,000 0,05304515 0,05346356 ! angiogenesis GO:0001525 149 95 0,000 0,05304515 0,05344014 ! carboxylic acid transport GO:0046942 147 95 0,000 0,05304515 0,05341675 GO:0015849|organic acid transport, ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,05358979 0,05394158 ! in utero embryonic development GO:0001701 147 96 0,000 0,05358979 0,05391798 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,05358979 0,05389441 ! protein maturation GO:0051604 129 96 0,000 0,05358979 0,05387085 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,05413414 0,05439428 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,05413414 0,05437053 ! calcium ion transport GO:0006816 167 99 0,000 0,055222 0,05543893 ! extracellular structure organization GO:0043062 156 99 0,000 0,055222 0,05541474 ! protein import GO:0017038 156 99 0,000 0,055222 0,05539058 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,0557655 0,05591136 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,0557655 0,055887 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,0557655 0,05586266 ! divalent metal ion transport GO:0070838 171 100 0,000 0,0557655 0,05583834 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,0557655 0,05581404 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,0557655 0,05578976 ! protein localization in organelle GO:0033365 161 100 0,000 0,0557655 0,0557655