pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-b1/out-0.05-06-0.01-300-run-b1//th1-pval-1e-01-08-th2-pval-1e-02-02-th3-pval-1e-01-01-run-b1/go_data/3978-4-real-Loi_GPL570-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 2,000 3,394E-08 8,291E-05 ! positive regulation of cell cycle GO:0045787 96 48 2,000 1,04E-06 1,27E-03 ! positive regulation of viral genome replication GO:0045070 9 5 1,000 1,661E-06 1,353E-03 ! meiotic chromosome segregation GO:0045132 10 5 1,000 1,661E-06 1,014E-03 ! nucleotide-excision repair GO:0006289 91 57 2,000 1,755E-06 8,574E-04 ! regulation of retroviral genome replication GO:0045091 8 6 1,000 2,491E-06 1,014E-03 ! establishment of spindle localization GO:0051293 16 6 1,000 2,491E-06 8,693E-04 GO:0051653|spindle localization, ! chromosome segregation GO:0007059 127 67 2,000 2,866E-06 8,751E-04 ! phosphoinositide-mediated signaling GO:0048015 141 75 2,000 4,031E-06 1,094E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 4,648E-06 1,135E-03 ! DNA topological change GO:0006265 12 8 1,000 4,648E-06 1,032E-03 ! V(D)J recombination GO:0033151 34 10 1,000 7,466E-06 1,52E-03 ! DNA ligation GO:0006266 18 10 1,000 7,466E-06 1,403E-03 ! positive regulation of viral reproduction GO:0048524 19 10 1,000 7,466E-06 1,303E-03 ! natural killer cell mediated immunity GO:0002228 19 10 1,000 7,466E-06 1,216E-03 GO:0042267|natural killer cell mediated cytotoxicity, ! leukocyte mediated cytotoxicity GO:0001909 28 12 1,000 1,094E-05 1,671E-03 ! histone deacetylation GO:0016575 24 15 1,000 1,74E-05 2,5E-03 ! cell killing GO:0001906 32 15 1,000 1,74E-05 2,361E-03 ! negative regulation of cell cycle process GO:0010948 35 17 1,000 2,252E-05 2,896E-03 ! regulation of viral genome replication GO:0045069 30 18 1,000 2,533E-05 3,094E-03 ! protein amino acid deacetylation GO:0006476 34 20 1,000 3,144E-05 3,658E-03 ! cellular response to unfolded protein GO:0034620 35 20 1,000 3,144E-05 3,492E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! apoptotic nuclear changes GO:0030262 34 22 1,000 3,821E-05 4,059E-03 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 1,000 3,821E-05 3,89E-03 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 1,000 4,563E-05 4,459E-03 GO:0016444|somatic cell DNA recombination, ! regulation of viral reproduction GO:0050792 41 24 1,000 4,563E-05 4,288E-03 ! chromosome condensation GO:0030261 48 25 1,000 4,959E-05 4,487E-03 ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 5,371E-05 4,686E-03 ! positive regulation of nuclear division GO:0051785 41 26 1,000 5,371E-05 4,524E-03 GO:0045840|positive regulation of mitosis, ! somatic diversification of immune receptors GO:0002200 63 26 1,000 5,371E-05 4,374E-03 ! regulation of chromosome organization GO:0033044 49 27 1,000 5,799E-05 4,57E-03 ! fat cell differentiation GO:0045444 57 28 1,000 6,244E-05 4,767E-03 ! base-excision repair GO:0006284 41 28 1,000 6,244E-05 4,622E-03 ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 6,704E-05 4,817E-03 ! spindle organization GO:0007051 50 32 1,000 8,185E-05 5,713E-03 ! mitotic sister chromatid segregation GO:0000070 63 36 1,000 1,039E-04 7,048E-03 ! sister chromatid segregation GO:0000819 65 37 1,000 1,098E-04 7,248E-03 ! meiosis I GO:0007127 74 38 1,000 1,158E-04 7,447E-03 ! nucleus organization GO:0006997 73 40 1,000 1,285E-04 8,047E-03 ! cytokinesis GO:0000910 84 42 1,000 1,417E-04 8,656E-03 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 1,000 1,702E-04 0,01014191 ! response to calcium ion GO:0051592 94 49 1,000 1,933E-04 0,01124097 ! histone modification GO:0016570 104 52 1,000 2,177E-04 0,01237095 ! regulation of translational initiation GO:0006446 87 54 1,000 2,349E-04 0,01304077 ! covalent chromatin modification GO:0016569 115 54 1,000 2,349E-04 0,01275097 ! response to UV GO:0009411 120 55 1,000 2,437E-04 0,01294133 ! regulation of DNA replication GO:0006275 105 56 1,000 2,526E-04 0,01313189 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 1,000 2,618E-04 0,01332264 ! positive regulation of organelle organization GO:0010638 108 58 1,000 2,71E-04 0,01351355 ! establishment of organelle localization GO:0051656 122 59 1,000 2,805E-04 0,01370462 ! regulation of mitosis GO:0007088 112 63 1,000 3,198E-04 0,0153213 GO:0051783|regulation of nuclear division, ! lymphocyte mediated immunity GO:0002449 122 65 1,000 3,405E-04 0,01599602 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 1,000 4,412E-04 0,02033518 ! organelle localization GO:0051640 155 74 1,000 4,412E-04 0,0199586 ! leukocyte mediated immunity GO:0002443 136 75 1,000 4,531E-04 0,02012768 ! negative regulation of organelle organization GO:0010639 181 80 1,000 5,154E-04 0,02248347 ! meiosis GO:0007126 143 81 1,000 5,283E-04 0,02264272 GO:0051327|M phase of meiotic cell cycle, ! positive regulation of phosphorylation GO:0042327 149 81 1,000 5,283E-04 0,02225233 ! meiotic cell cycle GO:0051321 144 82 1,000 5,414E-04 0,02241658 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 5,546E-04 0,02258174 GO:0045937|positive regulation of phosphate metabolic process, ! response to metal ion GO:0010038 158 84 1,000 5,68E-04 0,02274775 ! response to inorganic substance GO:0010035 173 90 1,000 6,516E-04 0,02567537 ! positive regulation of protein modification process GO:0031401 156 90 1,000 6,516E-04 0,02526783 ! response to unfolded protein GO:0006986 139 90 1,000 6,516E-04 0,02487302 ! regulation of cell cycle process GO:0010564 161 90 1,000 6,516E-04 0,02449036 ! response to protein stimulus GO:0051789 158 96 1,000 7,408E-04 0,02742154 ! regulation of DNA metabolic process GO:0051052 188 97 1,000 7,562E-04 0,02757423 ! interphase of mitotic cell cycle GO:0051329 224 98 1,000 7,718E-04 0,02772798 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 2,108E-03 0,07464955 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 2,108E-03 0,07358313 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 2,108E-03 0,07254675 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 2,108E-03 0,07153915 ! positive regulation of helicase activity GO:0051096 12 5 0,000 2,108E-03 0,07055916 ! neuron fate determination GO:0048664 7 5 0,000 2,108E-03 0,06960566 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 2,108E-03 0,06867759 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 2,108E-03 0,06777393 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 2,108E-03 0,06689375 ! polyol transport GO:0015791 12 5 0,000 2,108E-03 0,06603614 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 2,108E-03 0,06520024 ! response to superoxide GO:0000303 10 5 0,000 2,108E-03 0,06438524 ! negative regulation of bone resorption GO:0045779 10 5 0,000 2,108E-03 0,06359036 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 2,108E-03 0,06281487 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 2,108E-03 0,06205806 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 2,108E-03 0,06131927 ! female meiosis GO:0007143 10 5 0,000 2,108E-03 0,06059787 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 2,108E-03 0,05989324 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 2,108E-03 0,05920482 ! hypothalamus development GO:0021854 9 5 0,000 2,108E-03 0,05853203 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 2,108E-03 0,05787437 ! cobalt ion transport GO:0006824 11 5 0,000 2,108E-03 0,05723132 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 2,108E-03 0,05660241 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 2,108E-03 0,05598716 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 2,108E-03 0,05538515 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 2,108E-03 0,05479595 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 2,108E-03 0,05421915 ! embryonic camera-type eye development GO:0031076 12 5 0,000 2,108E-03 0,05365437 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 2,108E-03 0,05310123 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 2,108E-03 0,05255938 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 2,108E-03 0,05202848 ! transposition GO:0032196 9 5 0,000 2,108E-03 0,05150819 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 2,108E-03 0,05099821 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 2,108E-03 0,05049823 ! negative chemotaxis GO:0050919 16 5 0,000 2,108E-03 0,05000795 ! positive regulation of histone modification GO:0031058 6 5 0,000 2,108E-03 0,04952711 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 2,108E-03 0,04905542 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 2,108E-03 0,04859263 ! behavioral response to pain GO:0048266 10 5 0,000 2,108E-03 0,0481385 ! clathrin coat assembly GO:0048268 15 5 0,000 2,108E-03 0,04769277 ! Notch receptor processing GO:0007220 11 5 0,000 2,108E-03 0,04725522 ! regulation of dopamine uptake GO:0051584 9 5 0,000 2,108E-03 0,04682563 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 2,108E-03 0,04640378 ! micturition GO:0060073 9 5 0,000 2,108E-03 0,04598946 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 2,108E-03 0,04558247 ! copulation GO:0007620 9 5 0,000 2,108E-03 0,04518262 ! glial cell fate commitment GO:0021781 14 5 0,000 2,108E-03 0,04478973 ! protein maturation by protein folding GO:0022417 14 5 0,000 2,108E-03 0,04440361 ! bioluminescence GO:0008218 9 5 0,000 2,108E-03 0,04402409 ! spermidine metabolic process GO:0008216 7 5 0,000 2,108E-03 0,04365101 ! regulation of potassium ion transport GO:0043266 10 5 0,000 2,108E-03 0,04328419 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 2,108E-03 0,04292349 ! apoptotic cell clearance GO:0043277 23 5 0,000 2,108E-03 0,04256875 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 2,108E-03 0,04221983 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 2,108E-03 0,04187658 ! lipoprotein particle clearance GO:0034381 10 5 0,000 2,108E-03 0,04153886 ! grooming behavior GO:0007625 6 5 0,000 2,108E-03 0,04120655 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 2,108E-03 0,04087952 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 2,108E-03 0,04055763 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 2,108E-03 0,04024077 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 2,108E-03 0,03992883 ! response to protozoan GO:0001562 13 5 0,000 2,108E-03 0,03962168 ! positive regulation of glycolysis GO:0045821 13 5 0,000 2,108E-03 0,03931923 ! lymph vessel development GO:0001945 10 5 0,000 2,108E-03 0,03902136 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 2,108E-03 0,03872796 ! endochondral ossification GO:0001958 17 5 0,000 2,108E-03 0,03843895 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 2,108E-03 0,03815422 ! single strand break repair GO:0000012 8 5 0,000 2,108E-03 0,03787367 ! parathyroid gland development GO:0060017 14 5 0,000 2,108E-03 0,03759722 ! anagen GO:0042640 7 5 0,000 2,108E-03 0,03732478 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 2,108E-03 0,03705625 ! cytokine secretion GO:0050663 15 5 0,000 2,108E-03 0,03679156 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 2,108E-03 0,03653063 ! ceramide catabolic process GO:0046514 7 5 0,000 2,108E-03 0,03627337 ! skeletal myofibril assembly GO:0014866 12 5 0,000 2,108E-03 0,03601971 ! smooth muscle tissue development GO:0048745 32 5 0,000 2,108E-03 0,03576958 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 2,108E-03 0,03552289 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 2,108E-03 0,03527958 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 2,108E-03 0,03503959 ! cardiac muscle fiber development GO:0048739 12 5 0,000 2,108E-03 0,03480283 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 2,108E-03 0,03456926 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 2,108E-03 0,03433879 ! neutrophil mediated immunity GO:0002446 7 5 0,000 2,108E-03 0,03411138 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 2,108E-03 0,03388697 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 2,108E-03 0,03366548 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 2,108E-03 0,03344688 ! glycine biosynthetic process GO:0006545 7 5 0,000 2,108E-03 0,03323109 ! microvillus organization GO:0032528 8 5 0,000 2,108E-03 0,03301807 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 2,108E-03 0,03280776 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 2,108E-03 0,03260012 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 2,108E-03 0,03239509 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 2,108E-03 0,03219262 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 2,108E-03 0,03199266 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 2,108E-03 0,03179518 ! polyol catabolic process GO:0046174 9 5 0,000 2,108E-03 0,03160012 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 2,108E-03 0,03140743 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 2,108E-03 0,03121709 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 2,108E-03 0,03102903 ! muscle cell migration GO:0014812 8 5 0,000 2,108E-03 0,03084323 ! mitochondrial fission GO:0000266 8 5 0,000 2,108E-03 0,03065964 ! sister chromatid cohesion GO:0007062 15 5 0,000 2,108E-03 0,03047822 ! response to tumor necrosis factor GO:0034612 10 5 0,000 2,108E-03 0,03029894 ! mRNA transcription GO:0009299 10 5 0,000 2,108E-03 0,03012175 ! nerve growth factor processing GO:0032455 9 5 0,000 2,108E-03 0,02994662 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 2,108E-03 0,02977352 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 2,108E-03 0,02960241 ! anaerobic glycolysis GO:0019642 6 5 0,000 2,108E-03 0,02943325 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 2,108E-03 0,02926602 ! monocyte activation GO:0042117 10 5 0,000 2,108E-03 0,02910067 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 2,108E-03 0,02893719 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 2,108E-03 0,02877553 ! response to food GO:0032094 6 5 0,000 2,108E-03 0,02861566 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 2,108E-03 0,02845756 ! positive regulation of transporter activity GO:0032411 8 5 0,000 2,108E-03 0,0283012 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 2,108E-03 0,02814655 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 2,108E-03 0,02799358 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 2,108E-03 0,02784227 ! forebrain neuron development GO:0021884 13 5 0,000 2,108E-03 0,02769258 ! lipoprotein catabolic process GO:0042159 11 5 0,000 2,108E-03 0,02754449 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 2,108E-03 0,02739797 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 2,108E-03 0,02725301 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 2,108E-03 0,02710957 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 2,108E-03 0,02696764 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 2,108E-03 0,02682718 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 2,108E-03 0,02668818 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 2,108E-03 0,02655061 ! lipid glycosylation GO:0030259 7 5 0,000 2,108E-03 0,02641446 ! nucleobase transport GO:0015851 6 5 0,000 2,108E-03 0,02627969 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 2,108E-03 0,02614629 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 2,108E-03 0,02601424 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 2,108E-03 0,02588351 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 2,108E-03 0,0257541 ! basic amino acid transport GO:0015802 12 5 0,000 2,108E-03 0,02562597 ! cellular glucose homeostasis GO:0001678 6 5 0,000 2,108E-03 0,0254991 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 2,108E-03 0,02537349 ! actin nucleation GO:0045010 11 5 0,000 2,108E-03 0,02524911 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 2,108E-03 0,02512595 ! depurination GO:0045007 5 5 0,000 2,108E-03 0,02500398 ! depyrimidination GO:0045008 10 5 0,000 2,108E-03 0,02488318 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 2,108E-03 0,02476355 ! regulation of centrosome cycle GO:0046605 7 5 0,000 2,108E-03 0,02464507 ! G2/M transition checkpoint GO:0031576 8 5 0,000 2,108E-03 0,02452771 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 2,108E-03 0,02441146 ! zinc ion homeostasis GO:0055069 9 5 0,000 2,108E-03 0,02429632 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 2,108E-03 0,02418225 ! forebrain morphogenesis GO:0048853 13 5 0,000 2,108E-03 0,02406925 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 2,108E-03 0,0239573 ! activated T cell proliferation GO:0050798 16 5 0,000 2,108E-03 0,02384638 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 2,108E-03 0,02373649 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 2,108E-03 0,02362761 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 2,108E-03 0,02351972 ! positive regulation of organ growth GO:0046622 6 5 0,000 2,108E-03 0,02341281 ! gamma-delta T cell activation GO:0046629 6 5 0,000 2,108E-03 0,02330687 ! response to arsenic GO:0046685 11 5 0,000 2,108E-03 0,02320189 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 2,108E-03 0,02309784 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 2,108E-03 0,02299473 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 2,108E-03 0,02289253 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 2,108E-03 0,02279123 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 2,108E-03 0,02269083 ! response to mercury ion GO:0046689 8 5 0,000 2,108E-03 0,02259131 ! response to cadmium ion GO:0046686 7 5 0,000 2,108E-03 0,02249266 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 2,108E-03 0,02239487 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 2,108E-03 0,02229792 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 2,108E-03 0,02220181 ! bile acid biosynthetic process GO:0006699 7 5 0,000 2,108E-03 0,02210652 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 2,108E-03 0,02201205 ! ganglioside catabolic process GO:0006689 12 5 0,000 2,108E-03 0,02191838 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 2,108E-03 0,0218255 ! decidualization GO:0046697 11 5 0,000 2,108E-03 0,02173341 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 2,108E-03 0,0216421 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 2,108E-03 0,02155154 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 2,108E-03 0,02146175 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 2,108E-03 0,02137269 ! embryonic cleavage GO:0040016 6 5 0,000 2,108E-03 0,02128438 ! peroxisome fission GO:0016559 5 5 0,000 2,108E-03 0,02119679 ! histone demethylation GO:0016577 13 5 0,000 2,108E-03 0,02110991 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 2,108E-03 0,02102375 ! mitotic recombination GO:0006312 9 5 0,000 2,108E-03 0,02093829 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 2,108E-03 0,02085352 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 2,108E-03 0,02076943 ! metaphase plate congression GO:0051310 7 5 0,000 2,108E-03 0,02068602 ! regulation of sterol transport GO:0032371 7 5 0,000 2,108E-03 0,02060328 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 2,108E-03 0,02052119 ! enteric nervous system development GO:0048484 8 5 0,000 2,108E-03 0,02043976 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 2,108E-03 0,02035897 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 2,108E-03 0,02027882 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 2,108E-03 0,02019929 ! muscle cell proliferation GO:0033002 12 5 0,000 2,108E-03 0,02012039 ! skeletal muscle regeneration GO:0043403 8 5 0,000 2,108E-03 0,0200421 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 2,108E-03 0,01996441 ! B cell homeostasis GO:0001782 13 5 0,000 2,108E-03 0,01988733 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 2,108E-03 0,01981084 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 2,108E-03 0,01973494 ! metaphase GO:0051323 11 5 0,000 2,108E-03 0,01965961 ! melatonin biosynthetic process GO:0030187 7 5 0,000 2,108E-03 0,01958486 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 2,108E-03 0,01951068 ! cellular response to nutrient GO:0031670 8 5 0,000 2,108E-03 0,01943705 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 2,108E-03 0,01936398 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 2,108E-03 0,01929146 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 2,108E-03 0,01921947 ! regulation of hair follicle development GO:0051797 10 5 0,000 2,108E-03 0,01914803 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 2,108E-03 0,01907711 ! response to redox state GO:0051775 6 5 0,000 2,108E-03 0,01900671 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 2,108E-03 0,01893683 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 2,108E-03 0,01886747 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 2,108E-03 0,01879861 ! brown fat cell differentiation GO:0050873 7 5 0,000 2,108E-03 0,01873025 ! regulation of telomerase activity GO:0051972 7 5 0,000 2,108E-03 0,01866239 ! galactolipid metabolic process GO:0019374 7 5 0,000 2,108E-03 0,01859501 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 2,108E-03 0,01852813 ! porphyrin catabolic process GO:0006787 12 5 0,000 2,108E-03 0,01846172 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 2,108E-03 0,01839578 ! striatum development GO:0021756 14 5 0,000 2,108E-03 0,01833032 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 2,108E-03 0,01826532 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 2,108E-03 0,01820077 ! glial cell migration GO:0008347 10 5 0,000 2,108E-03 0,01813669 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 2,108E-03 0,01807305 ! neural plate morphogenesis GO:0001839 7 5 0,000 2,108E-03 0,01800986 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 2,108E-03 0,0179471 ! somatic stem cell maintenance GO:0035019 15 5 0,000 2,108E-03 0,01788479 ! T cell activation during immune response GO:0002286 9 5 0,000 2,108E-03 0,0178229 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 2,108E-03 0,01776144 ! negative regulation of lipase activity GO:0060192 8 5 0,000 2,108E-03 0,01770041 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 2,108E-03 0,01763979 ! neuroprotection GO:0043526 8 5 0,000 2,108E-03 0,01757959 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 2,108E-03 0,01751979 ! regulation of sensory perception GO:0051931 8 5 0,000 2,108E-03 0,0174604 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 2,108E-03 0,01740142 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 2,108E-03 0,01734283 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 2,108E-03 0,01728463 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 2,108E-03 0,01722682 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 2,108E-03 0,0171694 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 2,108E-03 0,01711236 ! sequestering of calcium ion GO:0051208 7 5 0,000 2,108E-03 0,01705569 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 2,108E-03 0,0169994 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 2,108E-03 0,01694348 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 2,108E-03 0,01688793 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 2,108E-03 0,01683274 ! spindle assembly GO:0051225 6 5 0,000 2,108E-03 0,01677791 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 2,108E-03 0,01672344 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 2,108E-03 0,01666932 ! protein palmitoylation GO:0018345 12 5 0,000 2,108E-03 0,01661555 ! drug metabolic process GO:0017144 7 5 0,000 2,108E-03 0,01656212 ! stem cell division GO:0017145 11 5 0,000 2,108E-03 0,01650904 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 2,108E-03 0,01645629 ! organ regeneration GO:0031100 7 5 0,000 2,108E-03 0,01640388 ! carnitine metabolic process GO:0009437 8 5 0,000 2,108E-03 0,01635181 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 2,108E-03 0,01630006 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 2,53E-03 0,01949453 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 2,53E-03 0,01943323 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 2,53E-03 0,01937231 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 2,53E-03 0,01931177 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 2,53E-03 0,01925161 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 2,53E-03 0,01919182 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 2,53E-03 0,0191324 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 2,53E-03 0,01907335 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 2,53E-03 0,01901466 ! response to oxygen radical GO:0000305 11 6 0,000 2,53E-03 0,01895634 ! positive regulation of axon extension GO:0045773 13 6 0,000 2,53E-03 0,01889837 ! myoblast cell fate commitment GO:0048625 18 6 0,000 2,53E-03 0,01884075 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 2,53E-03 0,01878348 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 2,53E-03 0,01872656 ! regulation of interferon-beta production GO:0032648 8 6 0,000 2,53E-03 0,01866999 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 2,53E-03 0,01861375 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 2,53E-03 0,01855786 ! forebrain regionalization GO:0021871 9 6 0,000 2,53E-03 0,01850229 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 2,53E-03 0,01844706 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 2,53E-03 0,01839216 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 2,53E-03 0,01833758 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 2,53E-03 0,01828333 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 2,53E-03 0,0182294 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 2,53E-03 0,01817578 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 2,53E-03 0,01812248 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 2,53E-03 0,01806949 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 2,53E-03 0,01801681 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 2,53E-03 0,01796444 ! malate metabolic process GO:0006108 13 6 0,000 2,53E-03 0,01791236 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 2,53E-03 0,01786059 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 2,53E-03 0,01780912 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 2,53E-03 0,01775795 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 2,53E-03 0,01770707 ! protein refolding GO:0042026 15 6 0,000 2,53E-03 0,01765647 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 2,53E-03 0,01760617 ! opsonization GO:0008228 8 6 0,000 2,53E-03 0,01755615 ! mating behavior GO:0007617 7 6 0,000 2,53E-03 0,01750642 ! erythrocyte maturation GO:0043249 8 6 0,000 2,53E-03 0,01745697 ! embryonic hemopoiesis GO:0035162 16 6 0,000 2,53E-03 0,01740779 ! protein amino acid dealkylation GO:0008214 15 6 0,000 2,53E-03 0,01735889 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 2,53E-03 0,01731027 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 2,53E-03 0,01726192 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 2,53E-03 0,01721383 ! response to interferon-gamma GO:0034341 16 6 0,000 2,53E-03 0,01716602 ! toxin metabolic process GO:0009404 11 6 0,000 2,53E-03 0,01711846 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 2,53E-03 0,01707118 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 2,53E-03 0,01702415 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 2,53E-03 0,01697738 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 2,53E-03 0,01693087 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 2,53E-03 0,01688461 ! cGMP-mediated signaling GO:0019934 14 6 0,000 2,53E-03 0,0168386 ! dorsal spinal cord development GO:0021516 10 6 0,000 2,53E-03 0,01679284 ! activation of MAPKKK activity GO:0000185 12 6 0,000 2,53E-03 0,01674733 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 2,53E-03 0,01670207 ! thymic T cell selection GO:0045061 16 6 0,000 2,53E-03 0,01665705 ! sphingoid catabolic process GO:0046521 8 6 0,000 2,53E-03 0,01661227 ! protein lipoylation GO:0009249 10 6 0,000 2,53E-03 0,01656774 ! transepithelial chloride transport GO:0030321 12 6 0,000 2,53E-03 0,01652344 GO:0070633|transepithelial transport, ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 2,53E-03 0,01647938 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 2,53E-03 0,01643555 ! glutamate catabolic process GO:0006538 12 6 0,000 2,53E-03 0,01639195 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 2,53E-03 0,01634859 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 2,53E-03 0,01630545 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 2,53E-03 0,01626254 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 2,53E-03 0,01621986 ! hyperosmotic response GO:0006972 10 6 0,000 2,53E-03 0,0161774 ! L-serine biosynthetic process GO:0006564 7 6 0,000 2,53E-03 0,01613516 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 2,53E-03 0,01609314 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 2,53E-03 0,01605134 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 2,53E-03 0,01600976 ! urea metabolic process GO:0019627 7 6 0,000 2,53E-03 0,01596839 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 2,53E-03 0,01592723 ! neutrophil activation GO:0042119 7 6 0,000 2,53E-03 0,01588629 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 2,53E-03 0,01584555 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 2,53E-03 0,01580503 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 2,53E-03 0,01576471 ! paraxial mesoderm development GO:0048339 16 6 0,000 2,53E-03 0,01572459 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 2,53E-03 0,01568468 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 2,53E-03 0,01564498 ! neuron apoptosis GO:0051402 15 6 0,000 2,53E-03 0,01560547 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 2,53E-03 0,01556616 ! T cell mediated immunity GO:0002456 17 6 0,000 2,53E-03 0,01552705 ! negative regulation of platelet activation GO:0010544 9 6 0,000 2,53E-03 0,01548813 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 2,53E-03 0,01544941 ! carnitine transport GO:0015879 10 6 0,000 2,53E-03 0,01541089 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 2,53E-03 0,01537255 ! positive regulation of exocytosis GO:0045921 11 6 0,000 2,53E-03 0,01533441 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 2,53E-03 0,01529645 ! early endosome to late endosome transport GO:0045022 16 6 0,000 2,53E-03 0,01525868 ! 5S class rRNA transcription GO:0042791 13 6 0,000 2,53E-03 0,0152211 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 2,53E-03 0,0151837 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 2,53E-03 0,01514648 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 2,53E-03 0,01510945 ! sodium ion homeostasis GO:0055078 12 6 0,000 2,53E-03 0,0150726 ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 2,53E-03 0,01503593 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 2,53E-03 0,01499943 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 2,53E-03 0,01496311 ! response to UV-C GO:0010225 14 6 0,000 2,53E-03 0,01492697 ! astrocyte development GO:0014002 16 6 0,000 2,53E-03 0,014891 ! protein targeting to lysosome GO:0006622 12 6 0,000 2,53E-03 0,01485521 ! purine base biosynthetic process GO:0009113 17 6 0,000 2,53E-03 0,01481958 ! interaction with symbiont GO:0051702 14 6 0,000 2,53E-03 0,01478413 ! regulation of dendrite development GO:0050773 16 6 0,000 2,53E-03 0,01474884 ! peptidyl-arginine modification GO:0018195 13 6 0,000 2,53E-03 0,01471373 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 2,53E-03 0,01467878 ! response to copper ion GO:0046688 10 6 0,000 2,53E-03 0,01464399 ! response to exogenous dsRNA GO:0043330 13 6 0,000 2,53E-03 0,01460938 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 2,53E-03 0,01457492 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 2,53E-03 0,01454063 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 2,53E-03 0,01450649 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 2,53E-03 0,01447252 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 2,53E-03 0,01443871 ! regulation of dopamine secretion GO:0014059 14 6 0,000 2,53E-03 0,01440505 ! nucleoside catabolic process GO:0009164 10 6 0,000 2,53E-03 0,01437155 ! hair follicle maturation GO:0048820 8 6 0,000 2,53E-03 0,0143382 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 2,53E-03 0,01430501 ! Schwann cell development GO:0014044 15 6 0,000 2,53E-03 0,01427198 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 2,53E-03 0,01423909 ! response to pheromone GO:0019236 6 6 0,000 2,53E-03 0,01420636 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 2,53E-03 0,01417377 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 2,53E-03 0,01414134 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 2,53E-03 0,01410905 ! base conversion or substitution editing GO:0016553 6 6 0,000 2,53E-03 0,01407692 ! subpallium development GO:0021544 15 6 0,000 2,53E-03 0,01404492 ! neural tube patterning GO:0021532 8 6 0,000 2,53E-03 0,01401307 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 2,53E-03 0,01398137 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 2,53E-03 0,01394981 ! maintenance of organ identity GO:0048496 9 6 0,000 2,53E-03 0,01391839 ! G2 phase GO:0051319 16 6 0,000 2,53E-03 0,01388711 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 2,53E-03 0,01385598 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 2,53E-03 0,01382498 ! oxygen homeostasis GO:0032364 10 6 0,000 2,53E-03 0,01379412 ! establishment of planar polarity GO:0001736 7 6 0,000 2,53E-03 0,0137634 ! regulation of mast cell activation GO:0033003 13 6 0,000 2,53E-03 0,01373281 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 2,53E-03 0,01370236 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 2,53E-03 0,01367205 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 2,53E-03 0,01364187 ! receptor internalization GO:0031623 11 6 0,000 2,53E-03 0,01361182 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 2,53E-03 0,0135819 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 2,53E-03 0,01355212 ! neutrophil homeostasis GO:0001780 11 6 0,000 2,53E-03 0,01352246 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 2,53E-03 0,01349294 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 2,53E-03 0,01346354 ! protein deubiquitination GO:0016579 16 6 0,000 2,53E-03 0,01343427 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 2,53E-03 0,01340513 ! protein destabilization GO:0031648 9 6 0,000 2,53E-03 0,01337612 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 2,53E-03 0,01334723 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 2,53E-03 0,01331846 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 2,53E-03 0,01328982 ! regulation of viral transcription GO:0046782 11 6 0,000 2,53E-03 0,0132613 ! progesterone metabolic process GO:0042448 12 6 0,000 2,53E-03 0,0132329 ! negative regulation of axon extension GO:0030517 24 6 0,000 2,53E-03 0,01320463 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 2,53E-03 0,01317647 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 2,53E-03 0,01314844 ! triglyceride catabolic process GO:0019433 10 6 0,000 2,53E-03 0,01312052 ! determination of adult lifespan GO:0008340 17 6 0,000 2,53E-03 0,01309272 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 2,53E-03 0,01306504 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 2,53E-03 0,01303748 ! neural plate development GO:0001840 9 6 0,000 2,53E-03 0,01301003 ! catecholamine transport GO:0051937 9 6 0,000 2,53E-03 0,0129827 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 2,53E-03 0,01295548 ! sensory cilium assembly GO:0035058 10 6 0,000 2,53E-03 0,01292838 ! organ or tissue specific immune response GO:0002251 8 6 0,000 2,53E-03 0,01290139 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 2,53E-03 0,01287451 ! maternal placenta development GO:0001893 12 6 0,000 2,53E-03 0,01284775 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 2,53E-03 0,01282109 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 2,53E-03 0,01279455 ! negative regulation of B cell activation GO:0050869 14 6 0,000 2,53E-03 0,01276811 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 2,53E-03 0,01274179 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 2,53E-03 0,01271557 ! positive regulation of coagulation GO:0050820 13 6 0,000 2,53E-03 0,01268946 ! cellular anion homeostasis GO:0030002 11 6 0,000 2,53E-03 0,01266345 GO:0055081|anion homeostasis, ! tRNA transcription GO:0009304 17 7 0,000 2,951E-03 0,01474091 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 2,951E-03 0,01471083 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 2,951E-03 0,01468087 ! behavioral response to cocaine GO:0048148 14 7 0,000 2,951E-03 0,01465103 ! regulation of helicase activity GO:0051095 16 7 0,000 2,951E-03 0,01462131 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 2,951E-03 0,01459171 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 2,951E-03 0,01456224 ! sleep GO:0030431 16 7 0,000 2,951E-03 0,01453288 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 2,951E-03 0,01450364 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 2,951E-03 0,01447451 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 2,951E-03 0,01444551 ! prostate gland development GO:0030850 14 7 0,000 2,951E-03 0,01441661 ! nucleotide-sugar transport GO:0015780 11 7 0,000 2,951E-03 0,01438784 ! synaptonemal complex assembly GO:0007130 10 7 0,000 2,951E-03 0,01435918 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 2,951E-03 0,01433063 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 2,951E-03 0,0143022 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 2,951E-03 0,01427388 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 2,951E-03 0,01424567 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 2,951E-03 0,01421757 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 2,951E-03 0,01418958 ! SMAD protein complex assembly GO:0007183 13 7 0,000 2,951E-03 0,0141617 ! glycolipid transport GO:0046836 11 7 0,000 2,951E-03 0,01413394 ! protein amino acid sulfation GO:0006477 10 7 0,000 2,951E-03 0,01410628 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 2,951E-03 0,01407872 ! neuron adhesion GO:0007158 14 7 0,000 2,951E-03 0,01405128 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 2,951E-03 0,01402394 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 2,951E-03 0,01399671 ! establishment of tissue polarity GO:0007164 8 7 0,000 2,951E-03 0,01396959 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 2,951E-03 0,01394257 ! mRNA stabilization GO:0048255 18 7 0,000 2,951E-03 0,01391565 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 2,951E-03 0,01388884 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 2,951E-03 0,01386213 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 2,951E-03 0,01383552 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 2,951E-03 0,01380902 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 2,951E-03 0,01378261 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 2,951E-03 0,01375631 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 2,951E-03 0,01373011 ! lipoprotein transport GO:0042953 14 7 0,000 2,951E-03 0,01370401 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 2,951E-03 0,013678 ! rhythmic behavior GO:0007622 17 7 0,000 2,951E-03 0,0136521 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 2,951E-03 0,01362629 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 2,951E-03 0,01360058 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 2,951E-03 0,01357497 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 2,951E-03 0,01354945 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 2,951E-03 0,01352403 ! regulation of odontogenesis GO:0042481 14 7 0,000 2,951E-03 0,0134987 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 2,951E-03 0,01347347 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 2,951E-03 0,01344833 ! mechanosensory behavior GO:0007638 16 7 0,000 2,951E-03 0,01342329 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 2,951E-03 0,01339834 ! positive regulation of isotype switching GO:0045830 17 7 0,000 2,951E-03 0,01337348 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 2,951E-03 0,01334872 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 2,951E-03 0,01332404 ! protein-cofactor linkage GO:0018065 13 7 0,000 2,951E-03 0,01329946 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 2,951E-03 0,01327497 ! spinal cord patterning GO:0021511 14 7 0,000 2,951E-03 0,01325056 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 2,951E-03 0,01322625 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 2,951E-03 0,01320203 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 2,951E-03 0,01317789 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 2,951E-03 0,01315385 ! adrenal gland development GO:0030325 17 7 0,000 2,951E-03 0,01312989 ! cysteine metabolic process GO:0006534 13 7 0,000 2,951E-03 0,01310601 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 2,951E-03 0,01308223 ! ovulation GO:0030728 10 7 0,000 2,951E-03 0,01305853 ! adenohypophysis development GO:0021984 11 7 0,000 2,951E-03 0,01303491 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 2,951E-03 0,01301138 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 2,951E-03 0,01298794 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 2,951E-03 0,01296458 ! microtubule nucleation GO:0007020 21 7 0,000 2,951E-03 0,01294131 ! proline biosynthetic process GO:0006561 10 7 0,000 2,951E-03 0,01291811 ! tryptophan metabolic process GO:0006568 11 7 0,000 2,951E-03 0,012895 ! thyroid hormone generation GO:0006590 13 7 0,000 2,951E-03 0,01287198 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 2,951E-03 0,01284903 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 2,951E-03 0,01282617 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 2,951E-03 0,01280339 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 2,951E-03 0,01278069 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 2,951E-03 0,01275807 ! galactose metabolic process GO:0006012 13 7 0,000 2,951E-03 0,01273552 ! vesicle fusion GO:0006906 20 7 0,000 2,951E-03 0,01271306 ! response to dietary excess GO:0002021 8 7 0,000 2,951E-03 0,01269068 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 2,951E-03 0,01266838 ! intracellular pH reduction GO:0051452 13 7 0,000 2,951E-03 0,01264615 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 2,951E-03 0,01262401 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 2,951E-03 0,01260194 ! organ growth GO:0035265 15 7 0,000 2,951E-03 0,01257994 ! nucleoside transport GO:0015858 11 7 0,000 2,951E-03 0,01255803 ! nucleoside salvage GO:0043174 11 7 0,000 2,951E-03 0,01253619 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 2,951E-03 0,01251442 ! male sex determination GO:0030238 15 7 0,000 2,951E-03 0,01249273 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 2,951E-03 0,01247112 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 2,951E-03 0,01244958 ! parturition GO:0007567 16 7 0,000 2,951E-03 0,01242812 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 2,951E-03 0,01240672 ! rRNA modification GO:0000154 14 7 0,000 2,951E-03 0,01238541 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 2,951E-03 0,01236416 ! spindle checkpoint GO:0031577 16 7 0,000 2,951E-03 0,01234299 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 2,951E-03 0,01232189 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 2,951E-03 0,01230087 ! monocyte differentiation GO:0030224 16 7 0,000 2,951E-03 0,01227991 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 2,951E-03 0,01225903 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 2,951E-03 0,01223821 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 2,951E-03 0,01221747 ! hyaluronan metabolic process GO:0030212 9 7 0,000 2,951E-03 0,0121968 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 2,951E-03 0,01217619 ! anterograde axon cargo transport GO:0008089 18 7 0,000 2,951E-03 0,01215566 ! fibrinolysis GO:0042730 11 7 0,000 2,951E-03 0,0121352 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 2,951E-03 0,0121148 ! skeletal muscle contraction GO:0003009 8 7 0,000 2,951E-03 0,01209448 ! eating behavior GO:0042755 8 7 0,000 2,951E-03 0,01207422 ! B cell lineage commitment GO:0002326 21 7 0,000 2,951E-03 0,01205403 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 2,951E-03 0,0120339 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 2,951E-03 0,01201385 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 2,951E-03 0,01199386 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 2,951E-03 0,01197393 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 2,951E-03 0,01195407 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 2,951E-03 0,01193428 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 2,951E-03 0,01191456 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 2,951E-03 0,0118949 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 2,951E-03 0,0118753 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 2,951E-03 0,01185577 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 2,951E-03 0,0118363 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 2,951E-03 0,0118169 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 2,951E-03 0,01179756 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 2,951E-03 0,01177828 ! histone ubiquitination GO:0016574 9 7 0,000 2,951E-03 0,01175907 ! regulation of meiosis GO:0040020 12 7 0,000 2,951E-03 0,01173991 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 2,951E-03 0,01172082 ! T cell lineage commitment GO:0002360 16 7 0,000 2,951E-03 0,0117018 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 2,951E-03 0,01168283 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 2,951E-03 0,01166393 ! membrane to membrane docking GO:0022614 14 7 0,000 2,951E-03 0,01164508 ! transcription termination GO:0006353 14 7 0,000 2,951E-03 0,0116263 ! coenzyme A metabolic process GO:0015936 12 7 0,000 2,951E-03 0,01160758 ! anaphase GO:0051322 18 7 0,000 2,951E-03 0,01158892 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 2,951E-03 0,01157032 ! axonal fasciculation GO:0007413 19 7 0,000 2,951E-03 0,01155177 ! negative regulation of nuclear division GO:0051784 15 7 0,000 2,951E-03 0,01153329 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 2,951E-03 0,01151487 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 2,951E-03 0,0114965 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 2,951E-03 0,0114782 ! diuresis GO:0030146 12 7 0,000 2,951E-03 0,01145995 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 2,951E-03 0,01144176 ! thiamin metabolic process GO:0006772 7 7 0,000 2,951E-03 0,01142362 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 2,951E-03 0,01140555 ! antibiotic transport GO:0042891 9 7 0,000 2,951E-03 0,01138753 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 2,951E-03 0,01136957 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 2,951E-03 0,01135166 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 2,951E-03 0,01133382 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 2,951E-03 0,01131602 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 2,951E-03 0,01129829 ! melanin biosynthetic process GO:0042438 10 7 0,000 2,951E-03 0,01128061 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 2,951E-03 0,01126298 ! dopamine biosynthetic process GO:0042416 18 7 0,000 2,951E-03 0,01124541 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 2,951E-03 0,01122789 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 2,951E-03 0,01121043 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 2,951E-03 0,01119302 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 2,951E-03 0,01117567 ! endosome to lysosome transport GO:0008333 12 7 0,000 2,951E-03 0,01115837 ! protein modification by small protein removal GO:0070646 19 7 0,000 2,951E-03 0,01114112 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 2,951E-03 0,01112393 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 2,951E-03 0,01110679 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 2,951E-03 0,0110897 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 2,951E-03 0,01107267 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 2,951E-03 0,01105569 ! muscle adaptation GO:0043500 13 7 0,000 2,951E-03 0,01103876 ! embryonic heart tube development GO:0035050 14 7 0,000 2,951E-03 0,01102188 ! retina homeostasis GO:0001895 12 7 0,000 2,951E-03 0,01100505 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 2,951E-03 0,01098827 ! protein amino acid prenylation GO:0018346 19 7 0,000 2,951E-03 0,01097155 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 2,951E-03 0,01095487 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 2,951E-03 0,01093825 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 3,371E-03 0,01247946 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 3,371E-03 0,01246058 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 3,371E-03 0,01244176 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 3,371E-03 0,01242299 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 3,371E-03 0,01240428 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 3,371E-03 0,01238563 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 3,371E-03 0,01236703 ! male meiosis GO:0007140 9 8 0,000 3,371E-03 0,01234849 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 3,371E-03 0,01233 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 3,371E-03 0,01231157 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 3,371E-03 0,0122932 ! meiotic prophase I GO:0007128 14 8 0,000 3,371E-03 0,01227488 ! response to zinc ion GO:0010043 12 8 0,000 3,371E-03 0,01225661 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 3,371E-03 0,0122384 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 3,371E-03 0,01222024 ! oligopeptide transport GO:0006857 16 8 0,000 3,371E-03 0,01220214 ! actin-myosin filament sliding GO:0033275 13 8 0,000 3,371E-03 0,01218409 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 3,371E-03 0,01216609 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 3,371E-03 0,01214815 ! signal peptide processing GO:0006465 12 8 0,000 3,371E-03 0,01213026 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 3,371E-03 0,01211242 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 3,371E-03 0,01209463 ! macrophage chemotaxis GO:0048246 12 8 0,000 3,371E-03 0,0120769 ! succinate metabolic process GO:0006105 17 8 0,000 3,371E-03 0,01205921 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 3,371E-03 0,01204158 ! membrane hyperpolarization GO:0060081 11 8 0,000 3,371E-03 0,012024 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 3,371E-03 0,01200648 ! estrogen metabolic process GO:0008210 17 8 0,000 3,371E-03 0,011989 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 3,371E-03 0,01197157 ! T-helper 1 type immune response GO:0042088 12 8 0,000 3,371E-03 0,0119542 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 3,371E-03 0,01193687 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 3,371E-03 0,0119196 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 3,371E-03 0,01190237 ! reflex GO:0060004 17 8 0,000 3,371E-03 0,0118852 ! endothelial cell differentiation GO:0045446 17 8 0,000 3,371E-03 0,01186807 ! glycerolipid catabolic process GO:0046503 14 8 0,000 3,371E-03 0,011851 ! hemoglobin metabolic process GO:0020027 14 8 0,000 3,371E-03 0,01183397 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 3,371E-03 0,01181699 ! pigment granule organization GO:0048753 17 8 0,000 3,371E-03 0,01180006 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 3,371E-03 0,01178318 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 3,371E-03 0,01176635 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 3,371E-03 0,01174956 ! astrocyte differentiation GO:0048708 19 8 0,000 3,371E-03 0,01173283 ! histidine catabolic process GO:0006548 10 8 0,000 3,371E-03 0,01171614 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 3,371E-03 0,01169949 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 3,371E-03 0,0116829 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 3,371E-03 0,01166635 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 3,371E-03 0,01164985 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 3,371E-03 0,01163339 ! regulation of pigmentation during development GO:0048070 25 8 0,000 3,371E-03 0,01161699 ! melanin metabolic process GO:0006582 17 8 0,000 3,371E-03 0,01160062 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 3,371E-03 0,01158431 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 3,371E-03 0,01156804 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 3,371E-03 0,01155181 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 3,371E-03 0,01153563 ! macrophage activation GO:0042116 13 8 0,000 3,371E-03 0,0115195 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 3,371E-03 0,01150341 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 3,371E-03 0,01148737 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 3,371E-03 0,01147137 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 3,371E-03 0,01145541 ! purine salvage GO:0043101 12 8 0,000 3,371E-03 0,0114395 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 3,371E-03 0,01142364 ! regulation of vascular permeability GO:0043114 12 8 0,000 3,371E-03 0,01140782 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 3,371E-03 0,01139204 ! osteoblast development GO:0002076 17 8 0,000 3,371E-03 0,0113763 ! positive regulation of vasodilation GO:0045909 14 8 0,000 3,371E-03 0,01136061 ! negative regulation of translational initiation GO:0045947 12 8 0,000 3,371E-03 0,01134496 ! Schwann cell differentiation GO:0014037 21 8 0,000 3,371E-03 0,01132936 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 3,371E-03 0,0113138 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 3,371E-03 0,01129828 ! response to UV-B GO:0010224 17 8 0,000 3,371E-03 0,0112828 ! protein targeting to vacuole GO:0006623 14 8 0,000 3,371E-03 0,01126736 ! protein retention in ER lumen GO:0006621 14 8 0,000 3,371E-03 0,01125197 ! intermediate filament organization GO:0045109 12 8 0,000 3,371E-03 0,01123662 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 3,371E-03 0,01122131 ! cellular extravasation GO:0045123 13 8 0,000 3,371E-03 0,01120605 ! cardiac muscle cell development GO:0055013 14 8 0,000 3,371E-03 0,01119082 ! response to antibiotic GO:0046677 11 8 0,000 3,371E-03 0,01117564 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 3,371E-03 0,01116049 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 3,371E-03 0,01114539 ! response to tropane GO:0014073 15 8 0,000 3,371E-03 0,01113033 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 3,371E-03 0,01111531 ! melanosome transport GO:0032402 13 8 0,000 3,371E-03 0,01110033 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 0,000 3,371E-03 0,01108539 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 3,371E-03 0,01107049 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 3,371E-03 0,01105563 ! mast cell activation GO:0045576 14 8 0,000 3,371E-03 0,01104081 ! multicellular organismal aging GO:0010259 20 8 0,000 3,371E-03 0,01102603 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 3,371E-03 0,01101129 ! gas homeostasis GO:0033483 14 8 0,000 3,371E-03 0,01099659 ! dendrite morphogenesis GO:0048813 14 8 0,000 3,371E-03 0,01098192 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 3,371E-03 0,0109673 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 3,371E-03 0,01095272 ! nucleosome disassembly GO:0006337 14 8 0,000 3,371E-03 0,01093817 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 3,371E-03 0,01092366 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 3,371E-03 0,0109092 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 3,371E-03 0,01089477 ! establishment of chromosome localization GO:0051303 14 8 0,000 3,371E-03 0,01088037 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 3,371E-03 0,01086602 ! intracellular lipid transport GO:0032365 16 8 0,000 3,371E-03 0,0108517 ! response to tumor cell GO:0002347 16 8 0,000 3,371E-03 0,01083743 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 3,371E-03 0,01082318 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 3,371E-03 0,01080898 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 3,371E-03 0,01079481 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 3,371E-03 0,01078068 ! positive regulation of epidermis development GO:0045684 13 8 0,000 3,371E-03 0,01076659 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 3,371E-03 0,01075254 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 3,371E-03 0,01073852 ! hormone catabolic process GO:0042447 17 8 0,000 3,371E-03 0,01072454 ! glycolipid catabolic process GO:0019377 16 8 0,000 3,371E-03 0,01071059 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 3,371E-03 0,01069668 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 3,371E-03 0,01068281 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 3,371E-03 0,01066897 ! positive regulation of glucose import GO:0046326 8 8 0,000 3,371E-03 0,01065517 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 3,371E-03 0,0106414 ! adult feeding behavior GO:0008343 10 8 0,000 3,371E-03 0,01062767 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 3,371E-03 0,01061397 ! ATP catabolic process GO:0006200 11 8 0,000 3,371E-03 0,01060031 ! blastocyst growth GO:0001832 19 8 0,000 3,371E-03 0,01058669 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 3,371E-03 0,0105731 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 3,371E-03 0,01055954 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 3,371E-03 0,01054602 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 3,371E-03 0,01053254 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 3,371E-03 0,01051908 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 3,371E-03 0,01050567 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 3,371E-03 0,01049228 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 3,371E-03 0,01047894 ! amino sugar catabolic process GO:0046348 11 8 0,000 3,371E-03 0,01046562 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 3,371E-03 0,01045234 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 3,371E-03 0,01043909 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 3,371E-03 0,01042588 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 3,371E-03 0,0104127 ! behavioral response to nicotine GO:0035095 12 8 0,000 3,371E-03 0,01039955 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 3,371E-03 0,01038644 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 3,371E-03 0,01037335 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 3,371E-03 0,01036031 ! NAD biosynthetic process GO:0009435 17 8 0,000 3,371E-03 0,01034729 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 3,371E-03 0,01033431 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 3,371E-03 0,01032136 ! axon extension GO:0048675 16 9 0,000 3,792E-03 0,01159471 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 3,792E-03 0,01158022 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 3,792E-03 0,01156576 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 3,792E-03 0,01155134 ! pentose-phosphate shunt GO:0006098 16 9 0,000 3,792E-03 0,01153695 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 3,792E-03 0,01152261 ! cell proliferation in forebrain GO:0021846 18 9 0,000 3,792E-03 0,01150829 ! neutral lipid catabolic process GO:0046461 14 9 0,000 3,792E-03 0,01149401 ! reproductive behavior GO:0019098 22 9 0,000 3,792E-03 0,01147977 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 3,792E-03 0,01146556 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 3,792E-03 0,01145139 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 3,792E-03 0,01143725 ! UTP metabolic process GO:0046051 10 9 0,000 3,792E-03 0,01142315 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 3,792E-03 0,01140908 ! induction of positive chemotaxis GO:0050930 17 9 0,000 3,792E-03 0,01139505 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 3,792E-03 0,01138105 ! artery development GO:0060840 25 9 0,000 3,792E-03 0,01136709 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 3,792E-03 0,01135315 ! regulation of glycolysis GO:0006110 20 9 0,000 3,792E-03 0,01133926 ! cerebral cortex cell migration GO:0021795 18 9 0,000 3,792E-03 0,0113254 ! equilibrioception GO:0050957 20 9 0,000 3,792E-03 0,01131157 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 3,792E-03 0,01129777 ! chemosensory behavior GO:0007635 21 9 0,000 3,792E-03 0,01128401 ! microtubule bundle formation GO:0001578 22 9 0,000 3,792E-03 0,01127029 ! middle ear morphogenesis GO:0042474 14 9 0,000 3,792E-03 0,01125659 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 3,792E-03 0,01124293 ! leukocyte degranulation GO:0043299 16 9 0,000 3,792E-03 0,0112293 ! ganglioside metabolic process GO:0001573 22 9 0,000 3,792E-03 0,01121571 ! negative regulation of endocytosis GO:0045806 12 9 0,000 3,792E-03 0,01120215 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 3,792E-03 0,01118862 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 3,792E-03 0,01117512 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 3,792E-03 0,01116166 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 3,792E-03 0,01114822 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 3,792E-03 0,01113483 ! protein targeting to ER GO:0045047 25 9 0,000 3,792E-03 0,01112146 ! ceramide biosynthetic process GO:0046513 20 9 0,000 3,792E-03 0,01110812 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 3,792E-03 0,01109482 ! T cell selection GO:0045058 27 9 0,000 3,792E-03 0,01108155 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 0,000 3,792E-03 0,01106831 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 3,792E-03 0,0110551 ! glycine catabolic process GO:0006546 15 9 0,000 3,792E-03 0,01104192 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 3,792E-03 0,01102878 ! endosome organization GO:0007032 20 9 0,000 3,792E-03 0,01101567 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 3,792E-03 0,01100258 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 3,792E-03 0,01098953 ! regulation of type I interferon production GO:0032479 12 9 0,000 3,792E-03 0,01097651 ! mannose metabolic process GO:0006013 13 9 0,000 3,792E-03 0,01096352 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 3,792E-03 0,01095056 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 3,792E-03 0,01093763 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 3,792E-03 0,01092473 ! Rac protein signal transduction GO:0016601 20 9 0,000 3,792E-03 0,01091187 ! receptor clustering GO:0043113 20 9 0,000 3,792E-03 0,01089903 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 3,792E-03 0,01088622 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 3,792E-03 0,01087344 ! retinol metabolic process GO:0042572 20 9 0,000 3,792E-03 0,0108607 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 3,792E-03 0,01084798 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 3,792E-03 0,01083529 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 3,792E-03 0,01082263 ! macrophage differentiation GO:0030225 15 9 0,000 3,792E-03 0,01081001 ! oligodendrocyte development GO:0014003 11 9 0,000 3,792E-03 0,01079741 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 3,792E-03 0,01078484 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 3,792E-03 0,0107723 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 3,792E-03 0,01075978 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 3,792E-03 0,0107473 ! response to amine stimulus GO:0014075 13 9 0,000 3,792E-03 0,01073485 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 3,792E-03 0,01072242 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 3,792E-03 0,01071003 ! erythrocyte development GO:0048821 17 9 0,000 3,792E-03 0,01069766 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 3,792E-03 0,01068532 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 3,792E-03 0,01067301 ! renal water homeostasis GO:0003091 15 9 0,000 3,792E-03 0,01066073 ! postreplication repair GO:0006301 25 9 0,000 3,792E-03 0,01064848 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 3,792E-03 0,01063625 ! icosanoid secretion GO:0032309 15 9 0,000 3,792E-03 0,01062405 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 3,792E-03 0,01061188 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 3,792E-03 0,01059974 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 3,792E-03 0,01058763 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 3,792E-03 0,01057554 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 3,792E-03 0,01056348 ! sterol catabolic process GO:0016127 14 9 0,000 3,792E-03 0,01055145 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 3,792E-03 0,01053945 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 3,792E-03 0,01052747 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 3,792E-03 0,01051552 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 3,792E-03 0,0105036 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 3,792E-03 0,0104917 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 3,792E-03 0,01047984 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 3,792E-03 0,01046799 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 3,792E-03 0,01045618 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 3,792E-03 0,01044439 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 3,792E-03 0,01043263 ! regulation of synaptogenesis GO:0051963 15 9 0,000 3,792E-03 0,01042089 ! purine base metabolic process GO:0006144 25 9 0,000 3,792E-03 0,01040918 ! pigment granule transport GO:0051904 17 9 0,000 3,792E-03 0,0103975 ! regulation of telomere maintenance GO:0032204 17 9 0,000 3,792E-03 0,01038585 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 3,792E-03 0,01037422 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 3,792E-03 0,01036261 ! regulation of muscle adaptation GO:0043502 14 9 0,000 3,792E-03 0,01035103 ! regulation of amino acid transport GO:0051955 12 9 0,000 3,792E-03 0,01033948 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 3,792E-03 0,01032795 ! mitochondrion localization GO:0051646 18 9 0,000 3,792E-03 0,01031645 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 4,213E-03 0,01144772 ! regulation of developmental growth GO:0048638 16 10 0,000 4,213E-03 0,011435 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 0,000 4,213E-03 0,01142231 ! autophagic vacuole formation GO:0000045 17 10 0,000 4,213E-03 0,01140965 ! negative regulation of blood pressure GO:0045776 26 10 0,000 4,213E-03 0,01139701 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 4,213E-03 0,0113844 ! associative learning GO:0008306 21 10 0,000 4,213E-03 0,01137182 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 4,213E-03 0,01135927 ! regulation of phosphatase activity GO:0010921 28 10 0,000 4,213E-03 0,01134675 ! phosphate transport GO:0006817 24 10 0,000 4,213E-03 0,01133425 ! cell volume homeostasis GO:0006884 17 10 0,000 4,213E-03 0,01132178 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 4,213E-03 0,01130934 ! CTP metabolic process GO:0046036 11 10 0,000 4,213E-03 0,01129693 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 4,213E-03 0,01128454 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 4,213E-03 0,01127218 ! GTP metabolic process GO:0046039 11 10 0,000 4,213E-03 0,01125985 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 4,213E-03 0,01124754 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 4,213E-03 0,01123526 ! social behavior GO:0035176 29 10 0,000 4,213E-03 0,01122301 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 4,213E-03 0,01121079 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 4,213E-03 0,01119859 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 4,213E-03 0,01118641 ! androgen metabolic process GO:0008209 17 10 0,000 4,213E-03 0,01117427 ! phospholipid efflux GO:0033700 19 10 0,000 4,213E-03 0,01116215 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 4,213E-03 0,01115005 ! bile acid and bile salt transport GO:0015721 15 10 0,000 4,213E-03 0,01113799 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 4,213E-03 0,01112595 ! positive regulation of heart contraction GO:0045823 17 10 0,000 4,213E-03 0,01111393 ! lung alveolus development GO:0048286 26 10 0,000 4,213E-03 0,01110194 ! pathogenesis GO:0009405 17 10 0,000 4,213E-03 0,01108998 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 4,213E-03 0,01107804 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 4,213E-03 0,01106613 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 4,213E-03 0,01105424 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 4,213E-03 0,01104238 ! endoderm development GO:0007492 18 10 0,000 4,213E-03 0,01103055 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 4,213E-03 0,01101874 ! arginine catabolic process GO:0006527 17 10 0,000 4,213E-03 0,01100695 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 4,213E-03 0,01099519 ! proline metabolic process GO:0006560 13 10 0,000 4,213E-03 0,01098346 ! glucan biosynthetic process GO:0009250 14 10 0,000 4,213E-03 0,01097175 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 4,213E-03 0,01096006 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 4,213E-03 0,0109484 ! reverse cholesterol transport GO:0043691 19 10 0,000 4,213E-03 0,01093677 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 4,213E-03 0,01092516 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 4,213E-03 0,01091357 ! B cell proliferation GO:0042100 19 10 0,000 4,213E-03 0,01090201 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 4,213E-03 0,01089048 ! regulation of sodium ion transport GO:0002028 26 10 0,000 4,213E-03 0,01087896 ! multicellular organism growth GO:0035264 19 10 0,000 4,213E-03 0,01086748 ! phagocytosis, engulfment GO:0006911 33 10 0,000 4,213E-03 0,01085601 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 4,213E-03 0,01084457 ! ruffle organization GO:0031529 17 10 0,000 4,213E-03 0,01083316 ! epithelial cell development GO:0002064 21 10 0,000 4,213E-03 0,01082177 ! lens development in camera-type eye GO:0002088 17 10 0,000 4,213E-03 0,0108104 ! retinoic acid metabolic process GO:0042573 14 10 0,000 4,213E-03 0,01079906 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 4,213E-03 0,01078774 ! positive regulation of translational initiation GO:0045948 12 10 0,000 4,213E-03 0,01077644 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 4,213E-03 0,01076517 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 4,213E-03 0,01075392 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 4,213E-03 0,01074269 ! motor axon guidance GO:0008045 22 10 0,000 4,213E-03 0,01073149 ! copper ion homeostasis GO:0055070 13 10 0,000 4,213E-03 0,01072031 ! regulation of bone resorption GO:0045124 25 10 0,000 4,213E-03 0,01070916 ! protein heterooligomerization GO:0051291 17 10 0,000 4,213E-03 0,01069803 ! regulation of gliogenesis GO:0014013 23 10 0,000 4,213E-03 0,01068692 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 4,213E-03 0,01067583 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 4,213E-03 0,01066477 ! segment specification GO:0007379 15 10 0,000 4,213E-03 0,01065373 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 4,213E-03 0,01064271 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 4,213E-03 0,01063172 ! blastoderm segmentation GO:0007350 19 10 0,000 4,213E-03 0,01062074 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 4,213E-03 0,01060979 ! response to dsRNA GO:0043331 23 10 0,000 4,213E-03 0,01059887 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 4,213E-03 0,01058796 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 4,213E-03 0,01057708 ! melanosome localization GO:0032400 16 10 0,000 4,213E-03 0,01056622 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 4,213E-03 0,01055539 ! regulation of B cell differentiation GO:0045577 24 10 0,000 4,213E-03 0,01054457 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 4,213E-03 0,01053378 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 4,213E-03 0,01052301 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 4,213E-03 0,01051226 ! induction of an organ GO:0001759 17 10 0,000 4,213E-03 0,01050153 ! leukocyte activation during immune response GO:0002366 15 10 0,000 4,213E-03 0,01049083 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 4,213E-03 0,01048014 ! protein sumoylation GO:0016925 17 10 0,000 4,213E-03 0,01046948 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 4,213E-03 0,01045884 ! hindbrain morphogenesis GO:0021575 19 10 0,000 4,213E-03 0,01044822 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 4,213E-03 0,01043763 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 4,213E-03 0,01042705 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 4,213E-03 0,0104165 ! salivary gland development GO:0007431 28 10 0,000 4,213E-03 0,01040597 ! ubiquinone metabolic process GO:0006743 17 10 0,000 4,213E-03 0,01039546 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 4,213E-03 0,01038497 ! midbrain development GO:0030901 14 10 0,000 4,213E-03 0,0103745 ! musculoskeletal movement GO:0050881 16 10 0,000 4,213E-03 0,01036405 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 4,213E-03 0,01035362 ! methionine biosynthetic process GO:0009086 21 10 0,000 4,213E-03 0,01034322 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 4,213E-03 0,01033283 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 4,213E-03 0,01032247 ! quaternary ammonium group transport GO:0015697 22 10 0,000 4,213E-03 0,01031212 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 4,213E-03 0,0103018 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 4,213E-03 0,0102915 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 4,213E-03 0,01028122 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 4,213E-03 0,01027096 ! establishment of pigment granule localization GO:0051905 18 10 0,000 4,213E-03 0,01026072 ! blastocyst formation GO:0001825 18 10 0,000 4,213E-03 0,0102505 ! regulation of fibrinolysis GO:0051917 20 10 0,000 4,213E-03 0,0102403 ! cerebellar cortex development GO:0021695 16 10 0,000 4,213E-03 0,01023012 ! positive regulation of amine transport GO:0051954 17 10 0,000 4,213E-03 0,01021996 ! response to nicotine GO:0035094 20 10 0,000 4,213E-03 0,01020982 ! negative regulation of immune effector process GO:0002698 23 10 0,000 4,213E-03 0,0101997 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 4,213E-03 0,0101896 ! negative regulation of muscle development GO:0048635 27 11 0,000 4,633E-03 0,01119527 ! respiratory burst GO:0045730 17 11 0,000 4,633E-03 0,01118421 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 4,633E-03 0,01117317 ! neuron fate specification GO:0048665 18 11 0,000 4,633E-03 0,01116215 ! telencephalon cell migration GO:0022029 23 11 0,000 4,633E-03 0,01115115 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 4,633E-03 0,01114018 ! thyroid gland development GO:0030878 26 11 0,000 4,633E-03 0,01112923 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 4,633E-03 0,01111829 ! synapsis GO:0007129 14 11 0,000 4,633E-03 0,01110738 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 4,633E-03 0,01109649 ! Golgi vesicle budding GO:0048194 26 11 0,000 4,633E-03 0,01108562 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 4,633E-03 0,01107478 ! response to pain GO:0048265 27 11 0,000 4,633E-03 0,01106395 ! detection of mechanical stimulus GO:0050982 22 11 0,000 4,633E-03 0,01105315 ! keratinocyte proliferation GO:0043616 19 11 0,000 4,633E-03 0,01104236 ! blood vessel remodeling GO:0001974 30 11 0,000 4,633E-03 0,0110316 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 4,633E-03 0,01102086 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 4,633E-03 0,01101014 ! bone resorption GO:0045453 16 11 0,000 4,633E-03 0,01099944 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 4,633E-03 0,01098876 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 4,633E-03 0,0109781 ! negative regulation of proteolysis GO:0045861 25 11 0,000 4,633E-03 0,01096746 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 4,633E-03 0,01095685 ! melanocyte differentiation GO:0030318 20 11 0,000 4,633E-03 0,01094625 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 4,633E-03 0,01093567 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 4,633E-03 0,01092512 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 4,633E-03 0,01091458 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 4,633E-03 0,01090407 ! regulation of intracellular pH GO:0051453 21 11 0,000 4,633E-03 0,01089357 ! substrate-bound cell migration GO:0006929 14 11 0,000 4,633E-03 0,0108831 ! UV protection GO:0009650 20 11 0,000 4,633E-03 0,01087264 ! adult heart development GO:0007512 16 11 0,000 4,633E-03 0,01086221 ! chondrocyte differentiation GO:0002062 27 11 0,000 4,633E-03 0,01085179 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 4,633E-03 0,0108414 ! macroautophagy GO:0016236 19 11 0,000 4,633E-03 0,01083103 ! temperature homeostasis GO:0001659 18 11 0,000 4,633E-03 0,01082067 ! behavioral fear response GO:0001662 27 11 0,000 4,633E-03 0,01081034 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 4,633E-03 0,01080002 ! negative regulation of ossification GO:0030279 27 11 0,000 4,633E-03 0,01078973 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 4,633E-03 0,01077945 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 4,633E-03 0,01076919 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 4,633E-03 0,01075896 ! alpha-beta T cell activation GO:0046631 26 11 0,000 4,633E-03 0,01074874 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 4,633E-03 0,01073854 ! regulation of organ growth GO:0046620 14 11 0,000 4,633E-03 0,01072836 ! pigment granule localization GO:0051875 20 11 0,000 4,633E-03 0,0107182 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 4,633E-03 0,01070806 ! vasoconstriction GO:0042310 20 11 0,000 4,633E-03 0,01069794 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 4,633E-03 0,01068784 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 4,633E-03 0,01067776 ! embryonic axis specification GO:0000578 19 11 0,000 4,633E-03 0,01066769 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 4,633E-03 0,01065765 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 4,633E-03 0,01064762 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 4,633E-03 0,01063761 ! nitric oxide metabolic process GO:0046209 17 11 0,000 4,633E-03 0,01062763 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 4,633E-03 0,01061766 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 4,633E-03 0,01060771 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 4,633E-03 0,01059777 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 4,633E-03 0,01058786 ! prophase GO:0051324 17 11 0,000 4,633E-03 0,01057796 ! neuroblast proliferation GO:0007405 25 11 0,000 4,633E-03 0,01056809 ! nucleosome positioning GO:0016584 15 11 0,000 4,633E-03 0,01055823 ! regulation of isotype switching GO:0045191 24 11 0,000 4,633E-03 0,01054839 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 4,633E-03 0,01053857 ! negative regulation of neurological system process GO:0031645 21 11 0,000 4,633E-03 0,01052876 ! apical protein localization GO:0045176 18 11 0,000 4,633E-03 0,01051898 ! acid secretion GO:0046717 20 11 0,000 4,633E-03 0,01050921 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 4,633E-03 0,01049946 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 4,633E-03 0,01048973 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 4,633E-03 0,01048002 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 4,633E-03 0,01047033 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 4,633E-03 0,01046065 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 4,633E-03 0,01045099 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 4,633E-03 0,01044135 ! cholesterol efflux GO:0033344 21 11 0,000 4,633E-03 0,01043173 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 4,633E-03 0,01042212 ! oocyte development GO:0048599 20 11 0,000 4,633E-03 0,01041253 ! negative regulation of glucose import GO:0046325 18 11 0,000 4,633E-03 0,01040296 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 4,633E-03 0,01039341 ! embryonic gut development GO:0048566 19 11 0,000 4,633E-03 0,01038387 ! regulation of organic acid transport GO:0032890 19 11 0,000 4,633E-03 0,01037436 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 4,633E-03 0,01036486 ! activation of innate immune response GO:0002218 16 11 0,000 4,633E-03 0,01035537 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 4,633E-03 0,01034591 ! cardiac cell differentiation GO:0035051 36 11 0,000 4,633E-03 0,01033646 ! lysogeny GO:0030069 22 11 0,000 4,633E-03 0,01032703 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 4,633E-03 0,01031761 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 4,633E-03 0,01030822 ! sequestering of metal ion GO:0051238 15 11 0,000 4,633E-03 0,01029884 ! regulation of embryonic development GO:0045995 35 11 0,000 4,633E-03 0,01028947 ! nucleus localization GO:0051647 22 11 0,000 4,633E-03 0,01028013 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 5,053E-03 0,0112023 ! positive regulation of blood pressure GO:0045777 18 12 0,000 5,053E-03 0,01119215 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 5,053E-03 0,01118201 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 5,053E-03 0,01117189 ! virus-host interaction GO:0019048 30 12 0,000 5,053E-03 0,01116179 ! regulation of B cell proliferation GO:0030888 22 12 0,000 5,053E-03 0,01115171 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 5,053E-03 0,01114164 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 5,053E-03 0,0111316 ! protein complex disassembly GO:0043241 28 12 0,000 5,053E-03 0,01112157 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 5,053E-03 0,01111156 ! regulation of cell projection assembly GO:0060491 33 12 0,000 5,053E-03 0,01110156 ! hippocampus development GO:0021766 29 12 0,000 5,053E-03 0,01109159 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 5,053E-03 0,01108163 ! cytokine biosynthetic process GO:0042089 23 12 0,000 5,053E-03 0,01107169 ! T cell proliferation GO:0042098 32 12 0,000 5,053E-03 0,01106177 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 5,053E-03 0,01105187 ! regulation of exit from mitosis GO:0007096 19 12 0,000 5,053E-03 0,01104198 ! ventral spinal cord development GO:0021517 25 12 0,000 5,053E-03 0,01103212 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 5,053E-03 0,01102227 ! drug transport GO:0015893 16 12 0,000 5,053E-03 0,01101243 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 5,053E-03 0,01100262 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 5,053E-03 0,01099282 ! tyrosine metabolic process GO:0006570 19 12 0,000 5,053E-03 0,01098304 ! polyamine metabolic process GO:0006595 18 12 0,000 5,053E-03 0,01097328 ! focal adhesion formation GO:0048041 37 12 0,000 5,053E-03 0,01096353 ! mitotic spindle organization GO:0007052 23 12 0,000 5,053E-03 0,01095381 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 5,053E-03 0,01094409 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 5,053E-03 0,0109344 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 5,053E-03 0,01092472 ! lipid digestion GO:0044241 21 12 0,000 5,053E-03 0,01091507 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 5,053E-03 0,01090542 ! entry into host cell GO:0030260 34 12 0,000 5,053E-03 0,0108958 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 5,053E-03 0,01088619 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 5,053E-03 0,0108766 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 5,053E-03 0,01086702 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 5,053E-03 0,01085747 ! protein targeting to peroxisome GO:0006625 27 12 0,000 5,053E-03 0,01084793 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 5,053E-03 0,0108384 ! regulation of phagocytosis GO:0050764 17 12 0,000 5,053E-03 0,01082889 ! snRNA metabolic process GO:0016073 30 12 0,000 5,053E-03 0,0108194 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 5,053E-03 0,01080993 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 5,053E-03 0,01080047 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 5,053E-03 0,01079103 ! cranial nerve development GO:0021545 23 12 0,000 5,053E-03 0,01078161 ! fucose catabolic process GO:0019317 25 12 0,000 5,053E-03 0,0107722 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 5,053E-03 0,01076281 ! histone acetylation GO:0016573 27 12 0,000 5,053E-03 0,01075343 ! mRNA polyadenylation GO:0006378 24 12 0,000 5,053E-03 0,01074407 ! autonomic nervous system development GO:0048483 24 12 0,000 5,053E-03 0,01073473 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 5,053E-03 0,0107254 ! zymogen activation GO:0031638 18 12 0,000 5,053E-03 0,01071609 ! peptidyl-lysine modification GO:0018205 21 12 0,000 5,053E-03 0,0107068 ! T cell homeostasis GO:0043029 28 12 0,000 5,053E-03 0,01069752 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 5,053E-03 0,01068826 ! glutathione biosynthetic process GO:0006750 15 12 0,000 5,053E-03 0,01067901 ! regulation of leukocyte migration GO:0002685 29 12 0,000 5,053E-03 0,01066978 ! oocyte differentiation GO:0009994 21 12 0,000 5,053E-03 0,01066057 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 5,053E-03 0,01065137 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 5,053E-03 0,01064219 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 5,053E-03 0,01063302 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 5,053E-03 0,01062387 ! defense response to fungus GO:0050832 15 12 0,000 5,053E-03 0,01061474 ! developmental induction GO:0031128 22 12 0,000 5,053E-03 0,01060562 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 5,053E-03 0,01059651 ! lamellipodium assembly GO:0030032 24 12 0,000 5,053E-03 0,01058743 ! response to cold GO:0009409 17 12 0,000 5,053E-03 0,01057835 ! establishment of cell polarity GO:0030010 21 12 0,000 5,053E-03 0,0105693 ! regulation of synapse organization GO:0050807 18 12 0,000 5,053E-03 0,01056026 ! localization within membrane GO:0051668 26 12 0,000 5,053E-03 0,01055123 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 5,473E-03 0,01141849 ! cGMP metabolic process GO:0046068 18 13 0,000 5,473E-03 0,01140875 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 5,473E-03 0,01139902 ! regulation of chemokine production GO:0032642 18 13 0,000 5,473E-03 0,01138931 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 5,473E-03 0,01137962 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 5,473E-03 0,01136994 ! peroxisomal transport GO:0043574 28 13 0,000 5,473E-03 0,01136028 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 5,473E-03 0,01135064 ! cartilage condensation GO:0001502 22 13 0,000 5,473E-03 0,01134101 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 5,473E-03 0,0113314 ! organelle fusion GO:0048284 36 13 0,000 5,473E-03 0,0113218 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 5,473E-03 0,01131223 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 5,473E-03 0,01130266 ! pseudouridine synthesis GO:0001522 19 13 0,000 5,473E-03 0,01129312 ! endocrine pancreas development GO:0031018 25 13 0,000 5,473E-03 0,01128359 ! positive regulation of cell growth GO:0030307 24 13 0,000 5,473E-03 0,01127407 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 5,473E-03 0,01126458 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 5,473E-03 0,01125509 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 5,473E-03 0,01124563 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 5,473E-03 0,01123618 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 5,473E-03 0,01122674 ! methionine metabolic process GO:0006555 31 13 0,000 5,473E-03 0,01121733 ! plasma membrane organization GO:0007009 27 13 0,000 5,473E-03 0,01120792 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 5,473E-03 0,01119854 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 5,473E-03 0,01118916 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 5,473E-03 0,01117981 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 5,473E-03 0,01117047 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 5,473E-03 0,01116114 ! cytokine metabolic process GO:0042107 24 13 0,000 5,473E-03 0,01115184 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 5,473E-03 0,01114254 ! exocrine system development GO:0035272 34 13 0,000 5,473E-03 0,01113327 ! asymmetric protein localization GO:0008105 24 13 0,000 5,473E-03 0,011124 ! membrane protein proteolysis GO:0033619 33 13 0,000 5,473E-03 0,01111476 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 5,473E-03 0,01110552 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 5,473E-03 0,01109631 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 5,473E-03 0,01108711 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 5,473E-03 0,01107792 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 5,473E-03 0,01106875 ! protein homotetramerization GO:0051289 24 13 0,000 5,473E-03 0,0110596 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 5,473E-03 0,01105046 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 5,473E-03 0,01104133 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 5,473E-03 0,01103222 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 5,473E-03 0,01102313 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 5,473E-03 0,01101405 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 5,473E-03 0,01100498 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 5,473E-03 0,01099593 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 5,473E-03 0,0109869 ! histone methylation GO:0016571 29 13 0,000 5,473E-03 0,01097787 ! chromatin silencing GO:0006342 29 13 0,000 5,473E-03 0,01096887 ! gland morphogenesis GO:0022612 31 13 0,000 5,473E-03 0,01095988 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 5,473E-03 0,0109509 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 5,473E-03 0,01094194 ! regulation of epidermis development GO:0045682 19 13 0,000 5,473E-03 0,01093299 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 5,473E-03 0,01092406 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 5,473E-03 0,01091514 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 5,473E-03 0,01090624 ! spleen development GO:0048536 24 13 0,000 5,473E-03 0,01089735 ! regulation of mRNA stability GO:0043488 32 13 0,000 5,473E-03 0,01088848 ! digestive tract morphogenesis GO:0048546 31 13 0,000 5,473E-03 0,01087962 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 5,473E-03 0,01087077 ! anterior/posterior axis specification GO:0009948 22 13 0,000 5,473E-03 0,01086194 ! regulation of RNA splicing GO:0043484 22 13 0,000 5,473E-03 0,01085313 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 5,473E-03 0,01084432 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 5,473E-03 0,01083554 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 5,473E-03 0,01082676 ! mRNA 3'-end processing GO:0031124 25 13 0,000 5,473E-03 0,010818 ! insulin secretion GO:0030073 24 13 0,000 5,473E-03 0,01080926 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 5,473E-03 0,01080053 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 5,473E-03 0,01079181 ! acrosome reaction GO:0007340 19 13 0,000 5,473E-03 0,01078311 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 5,473E-03 0,01077442 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 5,473E-03 0,01076574 ! rRNA transcription GO:0009303 28 14 0,000 5,893E-03 0,01158227 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 5,893E-03 0,01157296 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 5,893E-03 0,01156366 ! water transport GO:0006833 21 14 0,000 5,893E-03 0,01155438 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 5,893E-03 0,01154512 ! non-recombinational repair GO:0000726 29 14 0,000 5,893E-03 0,01153586 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 5,893E-03 0,01152663 ! retina development in camera-type eye GO:0060041 28 14 0,000 5,893E-03 0,01151741 ! hair follicle morphogenesis GO:0031069 27 14 0,000 5,893E-03 0,0115082 ! RNA polyadenylation GO:0043631 32 14 0,000 5,893E-03 0,01149901 ! lipid localization GO:0010876 32 14 0,000 5,893E-03 0,01148983 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 5,893E-03 0,01148067 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 5,893E-03 0,01147152 ! regulated secretory pathway GO:0045055 24 14 0,000 5,893E-03 0,01146239 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 5,893E-03 0,01145327 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 5,893E-03 0,01144416 ! arginine metabolic process GO:0006525 21 14 0,000 5,893E-03 0,01143508 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 5,893E-03 0,011426 ! cell-cell junction assembly GO:0007043 32 14 0,000 5,893E-03 0,01141694 ! regulation of heart rate GO:0002027 25 14 0,000 5,893E-03 0,01140789 ! fear response GO:0042596 34 14 0,000 5,893E-03 0,01139886 ! organic alcohol transport GO:0015850 29 14 0,000 5,893E-03 0,01138984 ! negative regulation of caspase activity GO:0043154 23 14 0,000 5,893E-03 0,01138084 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 5,893E-03 0,01137185 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 5,893E-03 0,01136287 ! neutral amino acid transport GO:0015804 28 14 0,000 5,893E-03 0,01135391 ! bone mineralization GO:0030282 18 14 0,000 5,893E-03 0,01134496 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 5,893E-03 0,01133603 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 5,893E-03 0,01132711 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 5,893E-03 0,01131821 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 5,893E-03 0,01130932 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 5,893E-03 0,01130044 ! regulation of cellular pH GO:0030641 27 14 0,000 5,893E-03 0,01129158 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 5,893E-03 0,01128273 ! ribosome assembly GO:0042255 18 14 0,000 5,893E-03 0,01127389 ! cerebellum development GO:0021549 23 14 0,000 5,893E-03 0,01126507 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 5,893E-03 0,01125626 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 5,893E-03 0,01124747 ! negative regulation of protein secretion GO:0050709 30 14 0,000 5,893E-03 0,01123869 ! response to gamma radiation GO:0010332 30 14 0,000 5,893E-03 0,01122992 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 5,893E-03 0,01122117 ! NADP metabolic process GO:0006739 24 14 0,000 5,893E-03 0,01121243 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 5,893E-03 0,0112037 ! oxygen transport GO:0015671 22 14 0,000 5,893E-03 0,01119499 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 5,893E-03 0,01118629 ! male genitalia development GO:0030539 26 14 0,000 5,893E-03 0,01117761 ! regulation of RNA stability GO:0043487 33 14 0,000 5,893E-03 0,01116894 ! regulation of axon extension GO:0030516 43 14 0,000 5,893E-03 0,01116028 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 5,893E-03 0,01115163 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 5,893E-03 0,011143 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 5,893E-03 0,01113438 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 6,313E-03 0,01191813 ! lactation GO:0007595 30 15 0,000 6,313E-03 0,01190893 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 6,313E-03 0,01189974 ! reproductive cellular process GO:0048610 22 15 0,000 6,313E-03 0,01189057 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 6,313E-03 0,0118814 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 6,313E-03 0,01187226 ! superoxide anion generation GO:0042554 22 15 0,000 6,313E-03 0,01186313 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 6,313E-03 0,01185401 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 6,313E-03 0,0118449 ! phospholipid catabolic process GO:0009395 27 15 0,000 6,313E-03 0,01183581 ! copper ion transport GO:0006825 22 15 0,000 6,313E-03 0,01182674 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 6,313E-03 0,01181767 ! cardiac muscle contraction GO:0060048 28 15 0,000 6,313E-03 0,01180862 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 6,313E-03 0,01179959 ! sulfate transport GO:0008272 27 15 0,000 6,313E-03 0,01179057 ! response to cAMP GO:0051591 25 15 0,000 6,313E-03 0,01178156 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 6,313E-03 0,01177257 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 6,313E-03 0,01176359 ! regulation of mRNA processing GO:0050684 26 15 0,000 6,313E-03 0,01175462 ! response to hexose stimulus GO:0009746 25 15 0,000 6,313E-03 0,01174567 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 6,313E-03 0,01173673 ! glycoprotein catabolic process GO:0006516 33 15 0,000 6,313E-03 0,0117278 ! vesicle coating GO:0006901 38 15 0,000 6,313E-03 0,01171889 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 6,313E-03 0,01171 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 6,313E-03 0,01170111 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 6,313E-03 0,01169224 ! regulation of exocytosis GO:0017157 26 15 0,000 6,313E-03 0,01168338 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 6,313E-03 0,01167454 ! G1/S transition checkpoint GO:0031575 37 15 0,000 6,313E-03 0,01166571 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 6,313E-03 0,01165689 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 6,313E-03 0,01164808 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 6,313E-03 0,01163929 ! regulation of vasodilation GO:0042312 27 15 0,000 6,313E-03 0,01163052 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 6,313E-03 0,01162175 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 6,313E-03 0,011613 ! water homeostasis GO:0030104 28 15 0,000 6,313E-03 0,01160426 ! cofactor transport GO:0051181 30 15 0,000 6,313E-03 0,01159554 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 6,313E-03 0,01158682 ! muscle maintenance GO:0046716 26 15 0,000 6,313E-03 0,01157813 ! protein-chromophore linkage GO:0018298 25 15 0,000 6,313E-03 0,01156944 ! intestinal absorption GO:0050892 31 15 0,000 6,313E-03 0,01156077 ! dopamine metabolic process GO:0042417 35 15 0,000 6,313E-03 0,01155211 ! cAMP biosynthetic process GO:0006171 25 15 0,000 6,313E-03 0,01154346 ! heme biosynthetic process GO:0006783 33 15 0,000 6,313E-03 0,01153483 ! lymphocyte homeostasis GO:0002260 33 15 0,000 6,313E-03 0,01152621 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 6,313E-03 0,0115176 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 6,313E-03 0,011509 ! L-fucose metabolic process GO:0042354 33 15 0,000 6,313E-03 0,01150042 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 6,313E-03 0,01149185 ! actin filament polymerization GO:0030041 27 15 0,000 6,313E-03 0,01148329 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 6,313E-03 0,01147475 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 6,732E-03 0,01222823 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 6,732E-03 0,01221914 ! positive regulation of cell size GO:0045793 29 16 0,000 6,732E-03 0,01221007 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 6,732E-03 0,01220101 ! dicarboxylic acid transport GO:0006835 47 16 0,000 6,732E-03 0,01219197 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 6,732E-03 0,01218294 ! bone remodeling GO:0046849 28 16 0,000 6,732E-03 0,01217392 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 6,732E-03 0,01216491 ! heterophilic cell adhesion GO:0007157 43 16 0,000 6,732E-03 0,01215592 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 6,732E-03 0,01214694 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 6,732E-03 0,01213798 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 6,732E-03 0,01212903 ! positive regulation of ion transport GO:0043270 23 16 0,000 6,732E-03 0,01212009 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 6,732E-03 0,01211117 ! startle response GO:0001964 28 16 0,000 6,732E-03 0,01210225 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 6,732E-03 0,01209336 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 6,732E-03 0,01208447 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 6,732E-03 0,0120756 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 6,732E-03 0,01206674 ! protein polyubiquitination GO:0000209 41 16 0,000 6,732E-03 0,01205789 ! glutamate metabolic process GO:0006536 25 16 0,000 6,732E-03 0,01204906 ! pituitary gland development GO:0021983 30 16 0,000 6,732E-03 0,01204024 ! response to osmotic stress GO:0006970 27 16 0,000 6,732E-03 0,01203143 ! lysosomal transport GO:0007041 31 16 0,000 6,732E-03 0,01202263 ! fructose metabolic process GO:0006000 25 16 0,000 6,732E-03 0,01201385 ! L-amino acid transport GO:0015807 33 16 0,000 6,732E-03 0,01200508 ! stem cell development GO:0048864 46 16 0,000 6,732E-03 0,01199633 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 6,732E-03 0,01198758 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 6,732E-03 0,01197885 ! intermediate filament-based process GO:0045103 36 16 0,000 6,732E-03 0,01197013 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 6,732E-03 0,01196143 ! negative regulation of immune response GO:0050777 38 16 0,000 6,732E-03 0,01195273 ! axon cargo transport GO:0008088 46 16 0,000 6,732E-03 0,01194405 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 6,732E-03 0,01193539 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 6,732E-03 0,01192673 ! DNA replication initiation GO:0006270 28 16 0,000 6,732E-03 0,01191809 ! neuron recognition GO:0008038 40 16 0,000 6,732E-03 0,01190946 ! mRNA splice site selection GO:0006376 44 16 0,000 6,732E-03 0,01190084 ! tissue regeneration GO:0042246 27 16 0,000 6,732E-03 0,01189224 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 6,732E-03 0,01188364 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 6,732E-03 0,01187506 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 6,732E-03 0,0118665 ! biomineral formation GO:0031214 22 16 0,000 6,732E-03 0,01185794 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 6,732E-03 0,0118494 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 6,732E-03 0,01184087 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 6,732E-03 0,01183235 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 6,732E-03 0,01182384 ! regulation of ATPase activity GO:0043462 26 16 0,000 6,732E-03 0,01181535 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 6,732E-03 0,01180687 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 6,732E-03 0,0117984 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 6,732E-03 0,01178994 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 6,732E-03 0,01178149 ! peptide hormone processing GO:0016486 27 16 0,000 6,732E-03 0,01177306 ! positive regulation of cell killing GO:0031343 36 17 0,000 7,152E-03 0,01249747 ! metencephalon development GO:0022037 32 17 0,000 7,152E-03 0,01248853 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 7,152E-03 0,01247961 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 7,152E-03 0,01247071 ! signal complex assembly GO:0007172 47 17 0,000 7,152E-03 0,01246181 ! filopodium assembly GO:0046847 42 17 0,000 7,152E-03 0,01245293 ! endothelial cell migration GO:0043542 31 17 0,000 7,152E-03 0,01244406 ! gene silencing by RNA GO:0031047 38 17 0,000 7,152E-03 0,0124352 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 7,152E-03 0,01242636 ! glial cell development GO:0021782 28 17 0,000 7,152E-03 0,01241753 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 7,152E-03 0,01240871 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 7,152E-03 0,0123999 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 7,152E-03 0,01239111 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 7,152E-03 0,01238232 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 7,152E-03 0,01237355 ! myoblast differentiation GO:0045445 50 17 0,000 7,152E-03 0,0123648 ! activation of MAPKK activity GO:0000186 43 17 0,000 7,152E-03 0,01235605 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 7,152E-03 0,01234732 ! regulation of survival gene product expression GO:0045884 38 17 0,000 7,152E-03 0,0123386 ! cardiac muscle tissue development GO:0048738 34 17 0,000 7,152E-03 0,01232989 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 7,152E-03 0,0123212 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 7,152E-03 0,01231252 ! complement activation, alternative pathway GO:0006957 19 17 0,000 7,152E-03 0,01230384 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 7,152E-03 0,01229519 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 7,152E-03 0,01228654 ! membrane budding GO:0006900 42 17 0,000 7,152E-03 0,01227791 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 7,152E-03 0,01226928 ! regulation of protein binding GO:0043393 33 17 0,000 7,152E-03 0,01226067 ! nucleobase metabolic process GO:0009112 43 17 0,000 7,152E-03 0,01225208 ! DNA unwinding during replication GO:0006268 26 17 0,000 7,152E-03 0,01224349 ! genitalia development GO:0048806 32 17 0,000 7,152E-03 0,01223492 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 7,152E-03 0,01222635 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 7,152E-03 0,0122178 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 7,152E-03 0,01220927 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 7,152E-03 0,01220074 ! neutrophil chemotaxis GO:0030593 29 17 0,000 7,152E-03 0,01219223 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 7,152E-03 0,01218372 ! steroid catabolic process GO:0006706 34 17 0,000 7,152E-03 0,01217523 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 7,152E-03 0,01216675 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 7,152E-03 0,01215829 ! gas transport GO:0015669 26 17 0,000 7,152E-03 0,01214983 ! organic cation transport GO:0015695 32 17 0,000 7,152E-03 0,01214139 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 7,152E-03 0,01213296 ! RNA 3'-end processing GO:0031123 37 17 0,000 7,152E-03 0,01212454 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 7,152E-03 0,01211613 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 7,571E-03 0,01281743 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 7,571E-03 0,01280855 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 7,571E-03 0,01279969 ! limbic system development GO:0021761 40 18 0,000 7,571E-03 0,01279084 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 7,571E-03 0,012782 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 7,571E-03 0,01277317 ! adult walking behavior GO:0007628 36 18 0,000 7,571E-03 0,01276436 ! patterning of blood vessels GO:0001569 43 18 0,000 7,571E-03 0,01275555 ! heart looping GO:0001947 34 18 0,000 7,571E-03 0,01274676 ! ciliary or flagellar motility GO:0001539 32 18 0,000 7,571E-03 0,01273798 ! centrosome cycle GO:0007098 26 18 0,000 7,571E-03 0,01272922 ! positive regulation of proteolysis GO:0045862 36 18 0,000 7,571E-03 0,01272046 ! regulation of defense response to virus GO:0050688 35 18 0,000 7,571E-03 0,01271172 ! epidermis morphogenesis GO:0048730 43 18 0,000 7,571E-03 0,01270299 ! glycine metabolic process GO:0006544 30 18 0,000 7,571E-03 0,01269427 ! glutamine metabolic process GO:0006541 29 18 0,000 7,571E-03 0,01268556 ! response to retinoic acid GO:0032526 31 18 0,000 7,571E-03 0,01267687 ! cell-substrate junction assembly GO:0007044 56 18 0,000 7,571E-03 0,01266819 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 0,000 7,571E-03 0,01265952 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 7,571E-03 0,01265086 ! DNA integration GO:0015074 32 18 0,000 7,571E-03 0,01264221 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 7,571E-03 0,01263357 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 7,571E-03 0,01262495 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 7,571E-03 0,01261634 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 7,571E-03 0,01260774 ! neural crest cell migration GO:0001755 41 18 0,000 7,571E-03 0,01259915 ! long-chain fatty acid transport GO:0015909 32 18 0,000 7,571E-03 0,01259057 ! sphingolipid catabolic process GO:0030149 32 18 0,000 7,571E-03 0,01258201 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 7,571E-03 0,01257345 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 7,571E-03 0,01256491 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 7,571E-03 0,01255638 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 7,571E-03 0,01254786 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 7,571E-03 0,01253936 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 7,571E-03 0,01253086 ! detection of bacterium GO:0016045 22 18 0,000 7,571E-03 0,01252238 ! nerve development GO:0021675 34 18 0,000 7,571E-03 0,01251391 ! defense response to virus GO:0051607 43 18 0,000 7,571E-03 0,01250544 ! microspike assembly GO:0030035 46 18 0,000 7,571E-03 0,01249699 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 7,571E-03 0,01248856 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 7,571E-03 0,01248013 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 7,99E-03 0,013162 ! positive regulation of translation GO:0045727 31 19 0,000 7,99E-03 0,01315313 ! negative regulation of defense response GO:0031348 27 19 0,000 7,99E-03 0,01314427 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 7,99E-03 0,01313542 ! neuron maturation GO:0042551 46 19 0,000 7,99E-03 0,01312659 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 7,99E-03 0,01311777 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 7,99E-03 0,01310896 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 7,99E-03 0,01310016 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 7,99E-03 0,01309138 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 7,99E-03 0,0130826 ! inositol metabolic process GO:0006020 33 19 0,000 7,99E-03 0,01307384 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 7,99E-03 0,01306509 ! memory GO:0007613 34 19 0,000 7,99E-03 0,01305635 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 7,99E-03 0,01304762 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 7,99E-03 0,0130389 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 7,99E-03 0,0130302 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 7,99E-03 0,01302151 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 7,99E-03 0,01301283 ! cerebral cortex development GO:0021987 40 19 0,000 7,99E-03 0,01300416 ! pigmentation during development GO:0048066 42 19 0,000 7,99E-03 0,0129955 ! response to vitamin A GO:0033189 32 19 0,000 7,99E-03 0,01298685 ! heme metabolic process GO:0042168 40 19 0,000 7,99E-03 0,01297822 ! neuromuscular junction development GO:0007528 43 19 0,000 7,99E-03 0,0129696 ! response to lipopolysaccharide GO:0032496 34 19 0,000 7,99E-03 0,01296098 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 7,99E-03 0,01295238 ! response to fungus GO:0009620 26 19 0,000 7,99E-03 0,01294379 ! peptide cross-linking GO:0018149 39 19 0,000 7,99E-03 0,01293522 ! protein export from nucleus GO:0006611 40 19 0,000 7,99E-03 0,01292665 ! heart process GO:0003015 32 19 0,000 7,99E-03 0,01291809 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 7,99E-03 0,01290955 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 7,99E-03 0,01290102 ! visual learning GO:0008542 38 19 0,000 7,99E-03 0,0128925 ! cellular pigmentation GO:0033059 37 19 0,000 7,99E-03 0,01288399 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 7,99E-03 0,01287549 ! peptide biosynthetic process GO:0043043 26 19 0,000 7,99E-03 0,012867 ! vitamin transport GO:0051180 31 19 0,000 7,99E-03 0,01285852 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 7,99E-03 0,01285006 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 7,99E-03 0,01284161 ! proximal/distal pattern formation GO:0009954 33 19 0,000 7,99E-03 0,01283316 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 7,99E-03 0,01282473 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 7,99E-03 0,01281631 ! cilium assembly GO:0042384 38 19 0,000 7,99E-03 0,0128079 ! peptide hormone secretion GO:0030072 32 19 0,000 7,99E-03 0,0127995 ! protein secretion GO:0009306 45 20 0,000 8,409E-03 0,01346168 ! protein import into nucleus, docking GO:0000059 42 20 0,000 8,409E-03 0,01345287 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 8,409E-03 0,01344406 ! positive regulation of ossification GO:0045778 50 20 0,000 8,409E-03 0,01343527 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 8,409E-03 0,01342649 ! skin development GO:0043588 42 20 0,000 8,409E-03 0,01341772 ! phosphoinositide phosphorylation GO:0046854 40 20 0,000 8,409E-03 0,01340896 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 8,409E-03 0,01340021 ! protein amino acid acetylation GO:0006473 41 20 0,000 8,409E-03 0,01339148 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 0,000 8,409E-03 0,01338275 ! aminoglycan catabolic process GO:0006026 25 20 0,000 8,409E-03 0,01337404 ! response to vitamin GO:0033273 36 20 0,000 8,409E-03 0,01336534 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 8,409E-03 0,01335665 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 8,409E-03 0,01334797 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 8,409E-03 0,0133393 ! bile acid metabolic process GO:0008206 34 20 0,000 8,409E-03 0,01333065 ! response to alkaloid GO:0043279 38 20 0,000 8,409E-03 0,013322 ! retinoid metabolic process GO:0001523 34 20 0,000 8,409E-03 0,01331337 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 8,409E-03 0,01330474 ! apoptotic mitochondrial changes GO:0008637 42 20 0,000 8,409E-03 0,01329613 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 8,409E-03 0,01328753 ! DNA duplex unwinding GO:0032508 30 20 0,000 8,409E-03 0,01327894 GO:0032392|DNA geometric change, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 8,409E-03 0,01327037 ! actin filament bundle formation GO:0051017 47 20 0,000 8,409E-03 0,0132618 ! body fluid secretion GO:0007589 33 20 0,000 8,409E-03 0,01325324 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 8,409E-03 0,0132447 ! peptide secretion GO:0002790 38 20 0,000 8,409E-03 0,01323616 ! behavioral interaction between organisms GO:0051705 47 20 0,000 8,409E-03 0,01322764 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 8,409E-03 0,01321913 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 8,409E-03 0,01321063 ! protein localization in mitochondrion GO:0070585 39 20 0,000 8,409E-03 0,01320214 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 8,409E-03 0,01319366 ! cell-cell junction organization GO:0045216 43 20 0,000 8,409E-03 0,01318519 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 8,409E-03 0,01317673 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 8,409E-03 0,01316829 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 8,409E-03 0,01315985 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 8,409E-03 0,01315142 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 8,409E-03 0,01314301 ! regulation of glucose import GO:0046324 30 20 0,000 8,409E-03 0,01313461 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 8,409E-03 0,01312621 ! negative regulation of T cell activation GO:0050868 41 20 0,000 8,409E-03 0,01311783 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 8,409E-03 0,01310946 ! negative regulation of translation GO:0017148 32 20 0,000 8,409E-03 0,0131011 ! negative regulation of coagulation GO:0050819 30 20 0,000 8,409E-03 0,01309275 ! regulation of cell killing GO:0031341 46 21 0,000 8,827E-03 0,01373593 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 8,827E-03 0,01372719 ! hormone secretion GO:0046879 39 21 0,000 8,827E-03 0,01371845 ! lipid phosphorylation GO:0046834 43 21 0,000 8,827E-03 0,01370973 ! cAMP metabolic process GO:0046058 41 21 0,000 8,827E-03 0,01370102 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 8,827E-03 0,01369232 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 8,827E-03 0,01368363 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 8,827E-03 0,01367496 ! ovarian follicle development GO:0001541 39 21 0,000 8,827E-03 0,01366629 ! smooth muscle contraction GO:0006939 48 21 0,000 8,827E-03 0,01365764 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 0,000 8,827E-03 0,01364899 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 8,827E-03 0,01364036 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 8,827E-03 0,01363174 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 8,827E-03 0,01362313 ! plasma membrane fusion GO:0045026 33 21 0,000 8,827E-03 0,01361453 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 8,827E-03 0,01360594 ! prostaglandin metabolic process GO:0006693 43 21 0,000 8,827E-03 0,01359736 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 8,827E-03 0,01358879 ! sensory perception of pain GO:0019233 33 21 0,000 8,827E-03 0,01358023 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 8,827E-03 0,01357169 ! diencephalon development GO:0021536 36 21 0,000 8,827E-03 0,01356315 ! collagen fibril organization GO:0030199 62 21 0,000 8,827E-03 0,01355462 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 8,827E-03 0,01354611 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 8,827E-03 0,01353761 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 8,827E-03 0,01352911 ! vitamin A metabolic process GO:0006776 35 21 0,000 8,827E-03 0,01352063 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 8,827E-03 0,01351216 ! collagen catabolic process GO:0030574 29 21 0,000 8,827E-03 0,0135037 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 8,827E-03 0,01349525 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 8,827E-03 0,01348681 ! sperm-egg recognition GO:0035036 23 21 0,000 8,827E-03 0,01347838 ! actin filament-based movement GO:0030048 47 21 0,000 8,827E-03 0,01346996 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 8,827E-03 0,01346155 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 9,246E-03 0,01409101 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 9,246E-03 0,01408222 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 9,246E-03 0,01407345 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 9,246E-03 0,01406469 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 9,246E-03 0,01405593 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 9,246E-03 0,01404719 ! microtubule-based transport GO:0010970 59 22 0,000 9,246E-03 0,01403846 ! hindlimb morphogenesis GO:0035137 47 22 0,000 9,246E-03 0,01402974 ! glutamate signaling pathway GO:0007215 48 22 0,000 9,246E-03 0,01402103 ! inactivation of MAPK activity GO:0000188 45 22 0,000 9,246E-03 0,01401234 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 9,246E-03 0,01400365 ! cellular response to starvation GO:0009267 37 22 0,000 9,246E-03 0,01399497 ! vacuolar transport GO:0007034 41 22 0,000 9,246E-03 0,01398631 ! central nervous system neuron development GO:0021954 47 22 0,000 9,246E-03 0,01397765 ! fucose metabolic process GO:0006004 44 22 0,000 9,246E-03 0,01396901 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 9,246E-03 0,01396038 ! D-ribose metabolic process GO:0006014 36 22 0,000 9,246E-03 0,01395175 ! ureteric bud development GO:0001657 50 22 0,000 9,246E-03 0,01394314 ! cell aging GO:0007569 48 22 0,000 9,246E-03 0,01393454 ! stem cell differentiation GO:0048863 57 22 0,000 9,246E-03 0,01392595 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 9,246E-03 0,01391737 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 9,246E-03 0,0139088 ! cytolysis GO:0019835 27 22 0,000 9,246E-03 0,01390024 ! renal system process GO:0003014 42 22 0,000 9,246E-03 0,01389169 ! vasodilation GO:0042311 40 22 0,000 9,246E-03 0,01388315 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 9,246E-03 0,01387462 ! positive regulation of locomotion GO:0040017 44 22 0,000 9,246E-03 0,01386611 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 9,246E-03 0,0138576 ! detection of chemical stimulus GO:0009593 42 22 0,000 9,246E-03 0,0138491 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 9,246E-03 0,01384062 ! positive regulation of intracellular transport GO:0032388 42 22 0,000 9,246E-03 0,01383214 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 9,246E-03 0,01382368 ! peptidyl-serine modification GO:0018209 50 22 0,000 9,246E-03 0,01381522 ! regulation of cytokine secretion GO:0050707 41 22 0,000 9,246E-03 0,01380678 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 9,246E-03 0,01379834 ! sarcomere organization GO:0045214 32 22 0,000 9,246E-03 0,01378992 ! positive regulation of B cell activation GO:0050871 42 22 0,000 9,246E-03 0,01378151 ! response to cytokine stimulus GO:0034097 69 22 0,000 9,246E-03 0,0137731 ! activation of JUN kinase activity GO:0007257 47 22 0,000 9,246E-03 0,01376471 ! terpenoid metabolic process GO:0006721 40 22 0,000 9,246E-03 0,01375633 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 9,246E-03 0,01374795 ! gut development GO:0048565 44 22 0,000 9,246E-03 0,01373959 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 9,246E-03 0,01373124 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 9,246E-03 0,0137229 ! protein stabilization GO:0050821 41 22 0,000 9,246E-03 0,01371456 ! positive regulation of DNA replication GO:0045740 44 23 0,000 9,664E-03 0,01432643 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 9,664E-03 0,01431775 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 9,664E-03 0,01430907 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 9,664E-03 0,0143004 ! gluconeogenesis GO:0006094 38 23 0,000 9,664E-03 0,01429174 ! glycerol metabolic process GO:0006071 40 23 0,000 9,664E-03 0,0142831 ! viral genome replication GO:0019079 44 23 0,000 9,664E-03 0,01427446 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 9,664E-03 0,01426584 ! glucosamine metabolic process GO:0006041 31 23 0,000 9,664E-03 0,01425722 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 9,664E-03 0,01424862 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 9,664E-03 0,01424003 ! regeneration GO:0031099 42 23 0,000 9,664E-03 0,01423144 ! axis specification GO:0009798 43 23 0,000 9,664E-03 0,01422287 ! visual behavior GO:0007632 46 23 0,000 9,664E-03 0,01421431 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 9,664E-03 0,01420575 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 9,664E-03 0,01419721 ! response to ethanol GO:0045471 47 23 0,000 9,664E-03 0,01418868 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 9,664E-03 0,01418016 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 9,664E-03 0,01417165 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 9,664E-03 0,01416315 ! peroxisome organization GO:0007031 43 23 0,000 9,664E-03 0,01415465 ! lysosome organization GO:0007040 47 23 0,000 9,664E-03 0,01414617 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 9,664E-03 0,0141377 ! vesicle targeting GO:0006903 49 23 0,000 9,664E-03 0,01412924 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 9,664E-03 0,01412079 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 9,664E-03 0,01411235 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 9,664E-03 0,01410392 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 9,664E-03 0,0140955 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 9,664E-03 0,01408709 ! DNA modification GO:0006304 36 23 0,000 9,664E-03 0,01407869 ! fatty acid transport GO:0015908 47 23 0,000 9,664E-03 0,0140703 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 9,664E-03 0,01406192 ! regulation of bone mineralization GO:0030500 54 23 0,000 9,664E-03 0,01405355 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 9,664E-03 0,01404519 ! hormone transport GO:0009914 41 23 0,000 9,664E-03 0,01403684 ! cell-cell recognition GO:0009988 28 23 0,000 9,664E-03 0,0140285 ! negative regulation of cytokine production GO:0001818 41 23 0,000 9,664E-03 0,01402017 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 9,664E-03 0,01401185 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 9,664E-03 0,01400354 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,01008254 0,01460085 ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,01008254 0,0145922 ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,01008254 0,01458356 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,01008254 0,01457493 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,01008254 0,01456631 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,01008254 0,0145577 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,01008254 0,01454911 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,01008254 0,01454052 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,01008254 0,01453194 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,01008254 0,01452337 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 0,000 0,01008254 0,01451481 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,01008254 0,01450626 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,01008254 0,01449773 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,01008254 0,0144892 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,01008254 0,01448068 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,01008254 0,01447217 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,01008254 0,01446367 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,01008254 0,01445519 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,01008254 0,01444671 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 52 24 0,000 0,01008254 0,01443824 ! leukotriene metabolic process GO:0006691 47 24 0,000 0,01008254 0,01442978 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,01008254 0,01442133 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,01008254 0,01441289 ! membrane depolarization GO:0051899 45 24 0,000 0,01008254 0,01440447 ! pallium development GO:0021543 56 24 0,000 0,01008254 0,01439605 ! oogenesis GO:0048477 44 24 0,000 0,01008254 0,01438764 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,01008254 0,01437924 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,01008254 0,01437085 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 0,01008254 0,01436247 ! platelet activation GO:0030168 41 24 0,000 0,01008254 0,0143541 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,01008254 0,01434574 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,01008254 0,01433739 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,01008254 0,01432905 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,01008254 0,01432072 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,01008254 0,0143124 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,01008254 0,01430409 ! regulation of amine transport GO:0051952 41 24 0,000 0,01008254 0,01429578 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,01008254 0,01428749 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,01050058 0,01487125 ! positive regulation of fibroblast proliferation GO:0048146 48 25 0,000 0,01050058 0,01486263 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,01050058 0,01485403 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 0,000 0,01050058 0,01484543 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,01050058 0,01483685 ! leukocyte adhesion GO:0007159 55 25 0,000 0,01050058 0,01482827 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,01050058 0,0148197 ! phototransduction GO:0007602 37 25 0,000 0,01050058 0,01481115 ! keratinization GO:0031424 37 25 0,000 0,01050058 0,0148026 ! vasculogenesis GO:0001570 49 25 0,000 0,01050058 0,01479406 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,01050058 0,01478554 ! vacuole organization GO:0007033 49 25 0,000 0,01050058 0,01477702 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,01050058 0,01476851 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,01050058 0,01476002 ! receptor metabolic process GO:0043112 53 25 0,000 0,01050058 0,01475153 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,01050058 0,01474305 ! regulation of behavior GO:0050795 48 25 0,000 0,01050058 0,01473458 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,01050058 0,01472612 ! interaction with host GO:0051701 66 25 0,000 0,01050058 0,01471767 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,01050058 0,01470924 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,01050058 0,01470081 ! immunoglobulin production GO:0002377 62 25 0,000 0,01050058 0,01469239 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,01050058 0,01468398 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,01050058 0,01467558 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,01050058 0,01466718 ! liver development GO:0001889 55 25 0,000 0,01050058 0,0146588 ! protein tetramerization GO:0051262 57 25 0,000 0,01050058 0,01465043 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,01091845 0,01522476 ! myelination GO:0042552 50 26 0,000 0,01091845 0,01521607 ! initiation of viral infection GO:0019059 60 26 0,000 0,01091845 0,0152074 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,01091845 0,01519873 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,01091845 0,01519008 ! molting cycle process GO:0022404 52 26 0,000 0,01091845 0,01518143 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,01091845 0,0151728 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,01091845 0,01516417 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,01091845 0,01515555 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,01091845 0,01514695 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,01091845 0,01513835 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,01091845 0,01512976 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,01091845 0,01512119 ! digestive system process GO:0022600 49 26 0,000 0,01091845 0,01511262 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,01091845 0,01510406 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,01091845 0,01509551 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 0,000 0,01091845 0,01508698 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,01091845 0,01507845 ! osteoblast differentiation GO:0001649 63 26 0,000 0,01091845 0,01506993 ! neural crest cell development GO:0014032 59 26 0,000 0,01091845 0,01506142 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,01091845 0,01505292 ! negative regulation of cell development GO:0010721 83 26 0,000 0,01091845 0,01504443 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,01091845 0,01503595 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,01091845 0,01502748 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,01091845 0,01501902 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,01091845 0,01501057 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,01091845 0,01500212 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,01091845 0,01499369 ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,01091845 0,01498527 ! blastocyst development GO:0001824 50 26 0,000 0,01091845 0,01497685 ! telomere organization GO:0032200 46 26 0,000 0,01091845 0,01496845 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,01091845 0,01496005 ! neural tube closure GO:0001843 58 26 0,000 0,01091845 0,01495167 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,01091845 0,01494329 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,01091845 0,01493492 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,01091845 0,01492657 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,01133616 0,01548895 ! embryonic pattern specification GO:0009880 49 27 0,000 0,01133616 0,01548029 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,01133616 0,01547164 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,01133616 0,015463 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,01133616 0,01545437 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,01133616 0,01544576 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,01133616 0,01543715 ! iron ion transport GO:0006826 65 27 0,000 0,01133616 0,01542855 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,01133616 0,01541996 ! superoxide metabolic process GO:0006801 41 27 0,000 0,01133616 0,01541137 ! tube lumen formation GO:0035148 59 27 0,000 0,01133616 0,0154028 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,01133616 0,01539424 ! insulin receptor signaling pathway GO:0008286 66 27 0,000 0,01133616 0,01538569 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,01133616 0,01537715 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,01133616 0,01536861 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,01133616 0,01536009 ! response to starvation GO:0042594 47 27 0,000 0,01133616 0,01535157 ! response to toxin GO:0009636 49 27 0,000 0,01133616 0,01534307 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,01133616 0,01533457 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,01133616 0,01532609 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,01133616 0,01531761 ! leukocyte proliferation GO:0070661 59 27 0,000 0,01133616 0,01530914 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,01133616 0,01530068 ! regulation of fibroblast proliferation GO:0048145 56 28 0,000 0,01175371 0,0158555 ! neuron fate commitment GO:0048663 52 28 0,000 0,01175371 0,01584675 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 0,000 0,01175371 0,015838 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,01175371 0,01582927 ! protein amino acid acylation GO:0043543 59 28 0,000 0,01175371 0,01582055 ! vesicle docking GO:0048278 55 28 0,000 0,01175371 0,01581184 ! circadian rhythm GO:0007623 56 28 0,000 0,01175371 0,01580314 ! dendrite development GO:0016358 67 28 0,000 0,01175371 0,01579445 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,01175371 0,01578576 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,01175371 0,01577709 ! sperm motility GO:0030317 37 28 0,000 0,01175371 0,01576843 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,01175371 0,01575977 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,01175371 0,01575113 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,01175371 0,01574249 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,01175371 0,01573386 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,01175371 0,01572525 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,01175371 0,01571664 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,01175371 0,01570804 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,01175371 0,01569945 ! glutathione metabolic process GO:0006749 42 28 0,000 0,01175371 0,01569088 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,01175371 0,01568231 ! lipid oxidation GO:0034440 48 28 0,000 0,01175371 0,01567375 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,01175371 0,0156652 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,01175371 0,01565665 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,01217109 0,0162038 ! translational initiation GO:0006413 66 29 0,000 0,01217109 0,01619497 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,01217109 0,01618615 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,01217109 0,01617735 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,01217109 0,01616855 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,01217109 0,01615976 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,01217109 0,01615099 ! primary neural tube formation GO:0014020 61 29 0,000 0,01217109 0,01614222 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,01217109 0,01613346 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,01217109 0,01612471 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,01217109 0,01611597 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,01217109 0,01610724 ! somitogenesis GO:0001756 52 29 0,000 0,01217109 0,01609852 ! synaptogenesis GO:0007416 46 29 0,000 0,01217109 0,01608981 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,01217109 0,01608111 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,01217109 0,01607241 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,01217109 0,01606373 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,01217109 0,01605506 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,0125883 0,01659645 ! phenol metabolic process GO:0018958 56 30 0,000 0,0125883 0,0165875 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,0125883 0,01657856 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,0125883 0,01656962 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,0125883 0,0165607 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,0125883 0,01655179 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,0125883 0,01654289 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,0125883 0,01653399 ! acute-phase response GO:0006953 50 30 0,000 0,0125883 0,01652511 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,0125883 0,01651623 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,0125883 0,01650737 ! myofibril assembly GO:0030239 50 30 0,000 0,0125883 0,01649851 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,0125883 0,01648966 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,0125883 0,01648083 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,0125883 0,016472 ! cell fate determination GO:0001709 64 30 0,000 0,0125883 0,01646318 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,0125883 0,01645437 ! phospholipid transport GO:0015914 65 30 0,000 0,0125883 0,01644557 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,0125883 0,01643678 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,0125883 0,016428 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,0125883 0,01641923 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,0125883 0,01641047 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,0125883 0,01640172 GO:0048871|multicellular organismal homeostasis, ! regulation of B cell activation GO:0050864 55 30 0,000 0,0125883 0,01639298 ! regulation of coagulation GO:0050818 52 30 0,000 0,0125883 0,01638424 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,01300535 0,01691804 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,01300535 0,01690904 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,01300535 0,01690004 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,01300535 0,01689106 ! cell junction assembly GO:0034329 85 31 0,000 0,01300535 0,01688208 ! regulation of innate immune response GO:0045088 57 31 0,000 0,01300535 0,01687312 ! ovulation cycle process GO:0022602 55 31 0,000 0,01300535 0,01686416 ! peptide transport GO:0015833 60 31 0,000 0,01300535 0,01685522 ! male gonad development GO:0008584 56 31 0,000 0,01300535 0,01684628 ! iron ion homeostasis GO:0055072 60 31 0,000 0,01300535 0,01683735 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,01300535 0,01682843 ! detection of light stimulus GO:0009583 44 31 0,000 0,01300535 0,01681952 ! cellular response to extracellular stimulus GO:0031668 52 31 0,000 0,01300535 0,01681062 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,01300535 0,01680173 ! natural killer cell activation GO:0030101 50 31 0,000 0,01300535 0,01679285 ! ensheathment of neurons GO:0007272 64 31 0,000 0,01300535 0,01678398 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,01300535 0,01677512 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,01300535 0,01676627 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,01300535 0,01675743 ! eye morphogenesis GO:0048592 65 31 0,000 0,01300535 0,01674859 ! response to heat GO:0009408 54 31 0,000 0,01300535 0,01673977 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,01300535 0,01673095 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,01342224 0,01725818 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,01342224 0,0172491 ! collagen metabolic process GO:0032963 49 32 0,000 0,01342224 0,01724003 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,01342224 0,01723097 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,01342224 0,01722192 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,01342224 0,01721288 ! metanephros development GO:0001656 81 32 0,000 0,01342224 0,01720385 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,01342224 0,01719483 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,01342224 0,01718582 ! muscle cell development GO:0055001 52 32 0,000 0,01342224 0,01717681 ! mesoderm formation GO:0001707 73 32 0,000 0,01342224 0,01716782 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,01342224 0,01715884 ! ovulation cycle GO:0042698 57 32 0,000 0,01342224 0,01714986 ! peripheral nervous system development GO:0007422 68 32 0,000 0,01342224 0,0171409 ! BMP signaling pathway GO:0030509 71 32 0,000 0,01342224 0,01713194 ! hindbrain development GO:0030902 65 32 0,000 0,01342224 0,017123 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,01342224 0,01711406 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,01342224 0,01710513 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,01342224 0,01709621 ! gene silencing GO:0016458 71 32 0,000 0,01342224 0,0170873 ! regulation of pH GO:0006885 56 33 0,000 0,01383896 0,01760864 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,01383896 0,01759947 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,01383896 0,01759032 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,01383896 0,01758117 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,01383896 0,01757203 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,01383896 0,0175629 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,01383896 0,01755379 ! response to ionizing radiation GO:0010212 74 33 0,000 0,01383896 0,01754468 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,01383896 0,01753558 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,01383896 0,01752649 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,01383896 0,0175174 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,01383896 0,01750833 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,01383896 0,01749927 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,01383896 0,01749022 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,01383896 0,01748117 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,01425552 0,01799806 ! glial cell differentiation GO:0010001 67 34 0,000 0,01425552 0,01798876 ! post-embryonic development GO:0009791 76 34 0,000 0,01425552 0,01797948 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,01425552 0,0179702 ! cholesterol transport GO:0030301 62 34 0,000 0,01425552 0,01796093 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,01425552 0,01795167 ! spliceosome assembly GO:0000245 75 34 0,000 0,01425552 0,01794242 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,01425552 0,01793318 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,01425552 0,01792395 ! formation of primary germ layer GO:0001704 76 34 0,000 0,01425552 0,01791473 ! cell fate specification GO:0001708 56 34 0,000 0,01425552 0,01790552 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,01425552 0,01789632 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,01425552 0,01788713 ! adult locomotory behavior GO:0008344 62 34 0,000 0,01425552 0,01787795 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,01425552 0,01786878 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,01467192 0,01838128 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,01467192 0,01837186 ! negative regulation of secretion GO:0051048 68 35 0,000 0,01467192 0,01836245 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,01467192 0,01835304 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,01467192 0,01834365 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,01467192 0,01833427 ! membrane docking GO:0022406 69 35 0,000 0,01467192 0,0183249 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,01467192 0,01831553 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,01467192 0,01830618 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,01467192 0,01829683 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,01467192 0,0182875 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,01467192 0,01827817 ! ceramide metabolic process GO:0006672 72 35 0,000 0,01467192 0,01826886 ! telencephalon development GO:0021537 81 35 0,000 0,01467192 0,01825955 ! sterol transport GO:0015918 63 35 0,000 0,01467192 0,01825025 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,01467192 0,01824096 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,01467192 0,01823169 ! placenta development GO:0001890 53 35 0,000 0,01467192 0,01822242 ! vesicle localization GO:0051648 70 35 0,000 0,01467192 0,01821316 ! regulation of muscle development GO:0048634 82 36 0,000 0,01508815 0,01872034 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,01508815 0,01871084 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,01508815 0,01870134 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,01508815 0,01869186 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,01508815 0,01868239 ! positive regulation of cell development GO:0010720 85 36 0,000 0,01508815 0,01867292 ! protein targeting to membrane GO:0006612 75 36 0,000 0,01508815 0,01866347 ! regulation of proteolysis GO:0030162 77 36 0,000 0,01508815 0,01865402 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,01508815 0,01864459 ! aerobic respiration GO:0009060 56 36 0,000 0,01508815 0,01863516 ! cytokine production GO:0001816 68 36 0,000 0,01508815 0,01862574 ! embryonic organ development GO:0048568 67 36 0,000 0,01508815 0,01861634 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,01508815 0,01860694 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,01508815 0,01859755 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,01550421 0,01910075 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,01550421 0,01909113 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,01550421 0,01908151 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,01550421 0,0190719 ! odontogenesis GO:0042476 74 37 0,000 0,01550421 0,0190623 ! actomyosin structure organization GO:0031032 68 37 0,000 0,01550421 0,01905271 ! cell junction organization GO:0034330 96 37 0,000 0,01550421 0,01904313 ! tissue remodeling GO:0048771 78 37 0,000 0,01550421 0,01903357 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,01550421 0,01902401 ! female gonad development GO:0008585 71 37 0,000 0,01550421 0,01901446 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,01550421 0,01900491 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,01550421 0,01899538 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,01550421 0,01898586 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,01550421 0,01897635 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,01592012 0,01947564 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,01592012 0,01946589 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,01592012 0,01945615 ! organic anion transport GO:0015711 82 38 0,000 0,01592012 0,01944642 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,01592012 0,0194367 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,01592012 0,019427 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,01592012 0,0194173 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,01592012 0,01940761 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,01592012 0,01939793 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,01592012 0,01938826 ! regulation of protein stability GO:0031647 77 38 0,000 0,01592012 0,0193786 ! spermatid development GO:0007286 69 38 0,000 0,01592012 0,01936895 ! glycogen metabolic process GO:0005977 63 38 0,000 0,01592012 0,01935931 ! pigment metabolic process GO:0042440 87 38 0,000 0,01592012 0,01934967 ! cellular response to insulin stimulus GO:0032869 85 38 0,000 0,01592012 0,01934005 ! neural tube formation GO:0001841 79 38 0,000 0,01592012 0,01933044 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,01633585 0,01982538 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,01633585 0,01981554 ! negative regulation of binding GO:0051100 71 39 0,000 0,01633585 0,0198057 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,01633585 0,01979588 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,01633585 0,01978606 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,01633585 0,01977626 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,01633585 0,01976646 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,01633585 0,01975668 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,01633585 0,0197469 ! positive regulation of leukocyte proliferation GO:0070665 70 39 0,000 0,01633585 0,01973714 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,01633585 0,01972738 ! glucan metabolic process GO:0044042 64 39 0,000 0,01633585 0,01971763 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,01675143 0,02020925 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 0,000 0,01675143 0,02019928 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,01675143 0,02018931 ! learning GO:0007612 82 40 0,000 0,01675143 0,02017936 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,01675143 0,02016941 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 75 40 0,000 0,01675143 0,02015948 ! mismatch repair GO:0006298 58 40 0,000 0,01675143 0,02014955 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,01675143 0,02013964 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,01675143 0,02012973 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,01675143 0,02011983 ! RNA export from nucleus GO:0006405 61 41 0,000 0,01716684 0,02060864 ! mRNA catabolic process GO:0006402 79 41 0,000 0,01716684 0,02059852 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,01716684 0,02058841 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,01716684 0,02057831 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,01716684 0,02056821 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,01716684 0,02055813 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,01716684 0,02054806 ! gliogenesis GO:0042063 91 41 0,000 0,01716684 0,020538 ! feeding behavior GO:0007631 69 41 0,000 0,01716684 0,02052794 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,01716684 0,0205179 ! mesenchymal cell development GO:0014031 94 41 0,000 0,01716684 0,02050787 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,01716684 0,02049784 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,01716684 0,02048783 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,01716684 0,02047783 ! spermatid differentiation GO:0048515 73 41 0,000 0,01716684 0,02046783 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,01716684 0,02045785 ! RNA modification GO:0009451 64 41 0,000 0,01716684 0,02044787 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,01758209 0,02093228 ! ear morphogenesis GO:0042471 64 42 0,000 0,01758209 0,02092208 ! organic ether metabolic process GO:0018904 59 42 0,000 0,01758209 0,0209119 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,01758209 0,02090172 ! regulation of intracellular protein transport GO:0033157 86 42 0,000 0,01758209 0,02089155 ! T cell differentiation GO:0030217 93 42 0,000 0,01758209 0,0208814 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,01758209 0,02087125 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,01758209 0,02086111 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,01758209 0,02085099 ! regulation of protein secretion GO:0050708 77 42 0,000 0,01758209 0,02084087 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,01758209 0,02083076 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,01758209 0,02082067 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,01799717 0,02130188 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 0,000 0,01799717 0,02129157 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,01799717 0,02128126 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,01799717 0,02127096 ! regulation of tube size GO:0035150 76 43 0,000 0,01799717 0,02126068 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,01799717 0,0212504 ! glucose transport GO:0015758 66 43 0,000 0,01799717 0,02124014 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,01799717 0,02122988 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,01799717 0,02121963 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,01799717 0,0212094 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,01799717 0,02119917 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,01799717 0,02118896 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,01799717 0,02117875 ! segmentation GO:0035282 78 43 0,000 0,01799717 0,02116855 ! ion transmembrane transport GO:0034220 79 43 0,000 0,01799717 0,02115836 ! neuron migration GO:0001764 85 43 0,000 0,01799717 0,02114819 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,01799717 0,02113802 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,01841209 0,02161496 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,01841209 0,02160458 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,01841209 0,02159421 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,01841209 0,02158384 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,01841209 0,02157349 ! hexose transport GO:0008645 68 44 0,000 0,01841209 0,02156315 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,01841209 0,02155282 ! striated muscle contraction GO:0006941 85 44 0,000 0,01841209 0,0215425 ! phagocytosis GO:0006909 105 44 0,000 0,01841209 0,02153218 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,01841209 0,02152188 ! double-strand break repair GO:0006302 85 44 0,000 0,01841209 0,02151159 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,01882684 0,02198565 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,01882684 0,02197514 ! regulation of epithelial cell proliferation GO:0050678 122 45 0,000 0,01882684 0,02196465 ! induction of apoptosis by intracellular signals GO:0008629 95 45 0,000 0,01882684 0,02195417 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,01882684 0,02194369 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,01882684 0,02193323 ! biopolymer methylation GO:0043414 91 45 0,000 0,01882684 0,02192277 ! B cell differentiation GO:0030183 124 45 0,000 0,01882684 0,02191233 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,01882684 0,02190189 ! female gamete generation GO:0007292 71 45 0,000 0,01882684 0,02189147 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,01882684 0,02188105 ! polyol metabolic process GO:0019751 77 45 0,000 0,01882684 0,02187065 ! developmental growth GO:0048589 88 45 0,000 0,01882684 0,02186026 ! maintenance of location in cell GO:0051651 101 45 0,000 0,01882684 0,02184987 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,01924143 0,02232043 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,01924143 0,02230984 ! glycolysis GO:0006096 71 46 0,000 0,01924143 0,02229925 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 0,000 0,01924143 0,02228868 ! regulation of gene-specific transcription GO:0032583 102 46 0,000 0,01924143 0,02227812 ! leukocyte migration GO:0050900 75 46 0,000 0,01924143 0,02226756 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,01924143 0,02225702 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,01924143 0,02224649 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,01924143 0,02223596 ! pigmentation GO:0043473 103 46 0,000 0,01924143 0,02222545 ! cell growth GO:0016049 90 46 0,000 0,01924143 0,02221495 ! positive regulation of protein transport GO:0051222 80 46 0,000 0,01924143 0,02220445 ! neural tube development GO:0021915 91 47 0,000 0,01965586 0,02267199 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,01965586 0,02266129 ! response to insulin stimulus GO:0032868 98 47 0,000 0,01965586 0,0226506 ! positive regulation of defense response GO:0031349 88 48 0,000 0,02007013 0,02311708 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,02007013 0,02310618 ! mitochondrial transport GO:0006839 94 48 0,000 0,02007013 0,0230953 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,02007013 0,02308443 ! cellular component disassembly GO:0022411 89 48 0,000 0,02007013 0,02307356 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,02007013 0,02306271 ! endosome transport GO:0016197 127 48 0,000 0,02007013 0,02305187 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,02007013 0,02304104 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,02007013 0,02303021 ! male sex differentiation GO:0046661 93 48 0,000 0,02007013 0,0230194 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,02007013 0,0230086 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,02007013 0,02299781 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,02007013 0,02298702 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,02007013 0,02297625 ! methylation GO:0032259 97 48 0,000 0,02007013 0,02296549 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,02048423 0,02342836 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,02048423 0,02341739 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,02048423 0,02340644 ! JNK cascade GO:0007254 106 49 0,000 0,02048423 0,0233955 ! regulation of mast cell proliferation GO:0070666 89 49 0,000 0,02048423 0,02338457 ! protein homooligomerization GO:0051260 84 49 0,000 0,02048423 0,02337364 ! regulation of action potential GO:0001508 102 50 0,000 0,02089817 0,02383484 ! regulation of ion transport GO:0043269 86 50 0,000 0,02089817 0,02382372 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,02089817 0,0238126 ! endocrine system development GO:0035270 109 50 0,000 0,02089817 0,0238015 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,02089817 0,02379041 ! activation of caspase activity GO:0006919 95 50 0,000 0,02089817 0,02377933 ! regulation of ossification GO:0030278 123 50 0,000 0,02089817 0,02376826 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,02089817 0,0237572 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,02089817 0,02374615 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,02089817 0,02373511 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,02089817 0,02372408 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,02089817 0,02371306 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,02131194 0,02417134 ! viral infectious cycle GO:0019058 104 51 0,000 0,02131194 0,02416013 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,02131194 0,02414892 ! peptide metabolic process GO:0006518 80 51 0,000 0,02131194 0,02413773 ! response to temperature stimulus GO:0009266 84 51 0,000 0,02131194 0,02412654 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,02131194 0,02411537 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,02131194 0,0241042 ! positive regulation of binding GO:0051099 88 52 0,000 0,02172555 0,02456063 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,02172555 0,02454927 ! Notch signaling pathway GO:0007219 111 52 0,000 0,02172555 0,02453792 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,02172555 0,02452658 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,02172555 0,02451526 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,02172555 0,02450394 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,02172555 0,02449263 ! excretion GO:0007588 87 52 0,000 0,02172555 0,02448133 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,02172555 0,02447005 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,02172555 0,02445877 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,02172555 0,0244475 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,02172555 0,02443625 ! amino acid activation GO:0043038 98 52 0,000 0,02172555 0,024425 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,022139 0,02487837 ! positive regulation of growth GO:0045927 96 53 0,000 0,022139 0,02486694 ! inner ear development GO:0048839 89 53 0,000 0,022139 0,02485551 ! chromatin remodeling GO:0006338 122 53 0,000 0,022139 0,02484409 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,022139 0,02483268 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,022139 0,02482129 ! vesicle organization GO:0016050 127 53 0,000 0,022139 0,0248099 ! regulation of leukocyte proliferation GO:0070663 97 53 0,000 0,022139 0,02479853 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,022139 0,02478716 ! cartilage development GO:0051216 99 53 0,000 0,022139 0,02477581 ! synapse organization GO:0050808 102 53 0,000 0,022139 0,02476446 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,02255229 0,02521521 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,02255229 0,02520368 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,02255229 0,02519215 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 0,000 0,02255229 0,02518064 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,02255229 0,02516914 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,02255229 0,02515764 ! membrane fusion GO:0006944 122 54 0,000 0,02255229 0,02514616 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,02255229 0,02513469 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,02255229 0,02512323 ! regulation of cell shape GO:0008360 142 54 0,000 0,02255229 0,02511178 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,02255229 0,02510034 ! RNA catabolic process GO:0006401 103 55 0,000 0,02296541 0,0255485 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,02296541 0,02553687 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,02296541 0,02552525 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,02296541 0,02551364 ! cell recognition GO:0008037 98 55 0,000 0,02296541 0,02550205 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,02296541 0,02549046 ! cell maturation GO:0048469 107 55 0,000 0,02296541 0,02547888 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,02296541 0,02546732 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,02296541 0,02545576 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,02337837 0,02590175 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,02337837 0,02589001 ! glucose catabolic process GO:0006007 88 56 0,000 0,02337837 0,02587828 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,02337837 0,02586656 ! RNA elongation GO:0006354 90 56 0,000 0,02337837 0,02585485 ! chloride transport GO:0006821 102 57 0,000 0,02379117 0,02629947 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,02379117 0,02628757 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,02379117 0,02627569 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 131 57 0,000 0,02379117 0,02626381 ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,02379117 0,02625195 ! heart morphogenesis GO:0003007 105 57 0,000 0,02379117 0,0262401 ! regulation of intracellular transport GO:0032386 108 57 0,000 0,02379117 0,02622826 ! regulation of actin filament length GO:0030832 118 58 0,000 0,0242038 0,02667113 ! positive regulation of cell migration GO:0030335 137 58 0,000 0,0242038 0,0266591 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,0242038 0,02664709 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,0242038 0,02663508 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,0242038 0,02662309 ! aging GO:0007568 112 58 0,000 0,0242038 0,02661111 ! gastrulation GO:0007369 122 58 0,000 0,0242038 0,02659914 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,0242038 0,02658718 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,0242038 0,02657523 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,0242038 0,02656329 ! maintenance of location GO:0051235 124 58 0,000 0,0242038 0,02655136 ! nuclear export GO:0051168 110 59 0,000 0,02461627 0,02699172 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,02502858 0,0274315 ! lipid modification GO:0030258 112 60 0,000 0,02502858 0,0274192 ! DNA catabolic process GO:0006308 94 60 0,000 0,02502858 0,02740691 ! regulation of endocytosis GO:0030100 104 60 0,000 0,02502858 0,02739463 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,02502858 0,02738236 ! adult behavior GO:0030534 104 60 0,000 0,02502858 0,02737011 ! kidney development GO:0001822 133 60 0,000 0,02502858 0,02735786 ! positive regulation of secretion GO:0051047 110 61 0,000 0,02544073 0,02779593 ! regulation of cellular component size GO:0032535 125 61 0,000 0,02544073 0,0277835 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,02544073 0,02777109 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,02544073 0,02775868 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,02544073 0,02774629 ! regulation of heart contraction GO:0008016 123 61 0,000 0,02544073 0,02773391 ! camera-type eye development GO:0043010 126 61 0,000 0,02544073 0,02772154 ! proton transport GO:0015992 117 61 0,000 0,02544073 0,02770918 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,02544073 0,02769683 ! viral reproductive process GO:0022415 132 62 0,000 0,02585271 0,02813281 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,02585271 0,02812029 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,02585271 0,02810777 ! tRNA processing GO:0008033 102 62 0,000 0,02585271 0,02809527 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,02585271 0,02808278 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,02626453 0,02851744 ! mesoderm development GO:0007498 128 63 0,000 0,02626453 0,02850477 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,02626453 0,02849212 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,02626453 0,02847947 ! hydrogen transport GO:0006818 121 64 0,000 0,02667619 0,02891301 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,02667619 0,02890019 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,02667619 0,02888738 ! protein amino acid autophosphorylation GO:0046777 157 64 0,000 0,02667619 0,02887458 ! response to peptide hormone stimulus GO:0043434 129 64 0,000 0,02667619 0,02886179 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,02708768 0,02929403 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,02708768 0,02928106 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,02708768 0,02926811 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,02708768 0,02925518 ! positive regulation of cell motion GO:0051272 157 65 0,000 0,02708768 0,02924225 ! ear development GO:0043583 114 66 0,000 0,02749901 0,02967319 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,02749901 0,02966009 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,02749901 0,029647 ! gonad development GO:0008406 115 66 0,000 0,02749901 0,02963392 ! steroid hormone receptor signaling pathway GO:0030518 146 66 0,000 0,02749901 0,02962085 ! negative regulation of cell growth GO:0030308 142 67 0,000 0,02791019 0,0300505 ! activation of MAPK activity GO:0000187 124 67 0,000 0,02791019 0,03003726 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,02791019 0,03002403 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,02791019 0,03001082 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,02791019 0,02999762 ! secondary metabolic process GO:0019748 125 67 0,000 0,02791019 0,02998443 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,02791019 0,02997125 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,02832119 0,03039924 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,02832119 0,03038589 ! hexose catabolic process GO:0019320 113 68 0,000 0,02832119 0,03037255 ! extracellular matrix organization GO:0030198 146 68 0,000 0,02832119 0,03035923 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,02832119 0,03034591 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,02832119 0,03033261 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,02832119 0,03031932 ! viral reproduction GO:0016032 142 68 0,000 0,02832119 0,03030603 ! regulation of lipase activity GO:0060191 137 68 0,000 0,02832119 0,03029277 ! adaptive immune response GO:0002250 126 68 0,000 0,02832119 0,03027951 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,02832119 0,03026626 ! cell projection assembly GO:0030031 138 68 0,000 0,02832119 0,03025303 ! negative regulation of cell size GO:0045792 144 69 0,000 0,02873204 0,03067849 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,02873204 0,03066508 ! negative regulation of protein kinase activity GO:0006469 144 69 0,000 0,02873204 0,03065169 ! lung development GO:0030324 165 69 0,000 0,02873204 0,03063831 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,02873204 0,03062495 ! urogenital system development GO:0001655 149 69 0,000 0,02873204 0,03061159 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,02873204 0,03059825 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 0,000 0,02873204 0,03058491 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,02873204 0,03057159 ! developmental maturation GO:0021700 128 69 0,000 0,02873204 0,03055828 ! single fertilization GO:0007338 83 69 0,000 0,02873204 0,03054498 ! negative regulation of kinase activity GO:0033673 145 70 0,000 0,02914272 0,03096811 ! cell redox homeostasis GO:0045454 114 70 0,000 0,02914272 0,03095464 ! germ cell development GO:0007281 133 70 0,000 0,02914272 0,03094119 ! activation of immune response GO:0002253 120 70 0,000 0,02914272 0,03092775 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,02914272 0,03091432 ! cell cycle checkpoint GO:0000075 145 71 0,000 0,02955325 0,03133619 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,02955325 0,03132259 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,02955325 0,03130901 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 0,000 0,02955325 0,03129544 ! appendage morphogenesis GO:0035107 150 72 0,000 0,02996361 0,03171624 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,02996361 0,03170251 ! respiratory tube development GO:0030323 171 72 0,000 0,02996361 0,03168878 ! actin filament organization GO:0007015 167 72 0,000 0,02996361 0,03167507 ! B cell activation GO:0042113 179 72 0,000 0,02996361 0,03166137 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,02996361 0,03164768 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,02996361 0,03163401 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,02996361 0,03162034 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,02996361 0,03160669 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,02996361 0,03159305 ! appendage development GO:0048736 151 73 0,000 0,0303738 0,03201174 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,0303738 0,03199793 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,0303738 0,03198414 ! regulation of immune effector process GO:0002697 156 73 0,000 0,0303738 0,03197036 ! acute inflammatory response GO:0002526 118 74 0,000 0,03078384 0,03238799 ! amino acid transport GO:0006865 148 74 0,000 0,03078384 0,03237405 ! regulation of caspase activity GO:0043281 136 74 0,000 0,03078384 0,03236012 ! negative regulation of transferase activity GO:0051348 155 74 0,000 0,03078384 0,0323462 ! respiratory system development GO:0060541 175 74 0,000 0,03078384 0,0323323 ! regulation of transcription factor activity GO:0051090 137 75 0,000 0,03119372 0,03274871 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 143 75 0,000 0,03119372 0,03273464 ! reproductive structure development GO:0048608 131 75 0,000 0,03119372 0,03272059 ! eye development GO:0001654 155 75 0,000 0,03119372 0,03270654 ! axon guidance GO:0007411 162 75 0,000 0,03119372 0,03269251 ! rhythmic process GO:0048511 142 75 0,000 0,03119372 0,03267849 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,03160343 0,03309352 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,03160343 0,03307934 ! learning or memory GO:0007611 161 76 0,000 0,03160343 0,03306517 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,03160343 0,03305102 ! regulation of blood pressure GO:0008217 134 76 0,000 0,03160343 0,03303687 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,03160343 0,03302274 ! amine catabolic process GO:0009310 136 77 0,000 0,03201298 0,03343639 ! neurotransmitter transport GO:0006836 142 77 0,000 0,03201298 0,0334221 ! phosphoinositide metabolic process GO:0030384 146 77 0,000 0,03201298 0,03340782 ! regulation of endopeptidase activity GO:0052548 141 77 0,000 0,03201298 0,03339356 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,03201298 0,0333793 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,03201298 0,03336506 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,03201298 0,03335083 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,03201298 0,03333662 ! regulation of catabolic process GO:0009894 173 77 0,000 0,03201298 0,03332241 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,03242237 0,03373418 ! antigen processing and presentation GO:0019882 117 78 0,000 0,03242237 0,03371981 ! fertilization GO:0009566 99 78 0,000 0,03242237 0,03370547 ! positive regulation of lymphocyte activation GO:0051251 142 78 0,000 0,03242237 0,03369113 ! blood coagulation GO:0007596 151 79 0,000 0,0328316 0,03410187 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,0328316 0,03408737 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 0,000 0,0328316 0,03407289 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,0328316 0,03405842 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,0328316 0,03404397 ! protein oligomerization GO:0051259 149 79 0,000 0,0328316 0,03402952 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,0328316 0,03401509 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,03324066 0,0344243 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,03324066 0,03440972 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,03324066 0,03439514 ! muscle cell differentiation GO:0042692 178 81 0,000 0,03364957 0,03480351 ! response to hypoxia GO:0001666 178 81 0,000 0,03364957 0,03478878 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,03364957 0,03477406 ! regulation of peptidase activity GO:0052547 150 82 0,000 0,03405831 0,03518158 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,03405831 0,03516672 ! protein import into nucleus GO:0006606 174 82 0,000 0,03405831 0,03515186 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,03446689 0,03555854 ! exocytosis GO:0006887 153 83 0,000 0,03446689 0,03554353 ! response to drug GO:0042493 149 83 0,000 0,03446689 0,03552853 ! response to oxygen levels GO:0070482 183 83 0,000 0,03446689 0,03551354 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,03446689 0,03549857 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,03446689 0,03548361 ! nuclear import GO:0051170 177 83 0,000 0,03446689 0,03546867 ! inorganic anion transport GO:0015698 156 83 0,000 0,03446689 0,03545373 ! T cell activation GO:0042110 189 84 0,000 0,03487531 0,03585875 ! response to nutrient GO:0007584 135 84 0,000 0,03487531 0,03584366 ! digestion GO:0007586 130 84 0,000 0,03487531 0,03582859 ! regulation of ligase activity GO:0051340 147 84 0,000 0,03487531 0,03581353 ! hemostasis GO:0007599 165 85 0,000 0,03528357 0,03621755 ! negative regulation of transport GO:0051051 164 85 0,000 0,03528357 0,03620234 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,03528357 0,03618714 ! negative regulation of growth GO:0045926 168 85 0,000 0,03528357 0,03617195 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,03528357 0,03615678 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,03528357 0,03614162 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,03528357 0,03612647 ! cellular response to hormone stimulus GO:0032870 182 85 0,000 0,03528357 0,03611134 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,03569167 0,03651371 ! regulation of lyase activity GO:0051339 169 86 0,000 0,03569167 0,03649843 ! positive regulation of cell activation GO:0050867 161 86 0,000 0,03569167 0,03648316 GO:0002696|positive regulation of leukocyte activation, ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,0360996 0,03688471 ! mitochondrion organization GO:0007005 159 87 0,000 0,0360996 0,03686929 ! alcohol catabolic process GO:0046164 142 87 0,000 0,0360996 0,03685388 ! nucleosome assembly GO:0006334 126 87 0,000 0,0360996 0,03683849 ! regulation of protein transport GO:0051223 165 87 0,000 0,0360996 0,0368231 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 143 88 0,000 0,03650738 0,03722351 ! amine biosynthetic process GO:0009309 146 88 0,000 0,03650738 0,03720798 ! sensory perception of smell GO:0007608 117 88 0,000 0,03650738 0,03719247 ! chromatin assembly GO:0031497 128 88 0,000 0,03650738 0,03717696 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,03650738 0,03716147 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,036915 0,03756074 ! regulation of DNA binding GO:0051101 167 89 0,000 0,036915 0,0375451 ! tube morphogenesis GO:0035239 194 89 0,000 0,036915 0,03752948 ! cellular defense response GO:0006968 123 89 0,000 0,036915 0,03751387 ! protein localization in nucleus GO:0034504 192 89 0,000 0,036915 0,03749827 ! regulation of neurological system process GO:0031644 175 89 0,000 0,036915 0,03748268 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,03732245 0,03788066 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,03772974 0,03827814 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! ossification GO:0001503 205 91 0,000 0,03772974 0,03826225 ! gland development GO:0048732 220 91 0,000 0,03772974 0,03824637 ! defense response to bacterium GO:0042742 112 91 0,000 0,03772974 0,03823051 ! bone development GO:0060348 206 92 0,000 0,03813687 0,03862702 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,03813687 0,03861102 ! regulation of cell adhesion GO:0030155 241 92 0,000 0,03813687 0,03859502 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,03854385 0,03899073 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,03854385 0,03897459 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,03854385 0,03895847 ! positive regulation of MAP kinase activity GO:0043406 174 93 0,000 0,03854385 0,03894236 ! vitamin metabolic process GO:0006766 153 93 0,000 0,03854385 0,03892626 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,03895066 0,03932085 ! female pregnancy GO:0007565 166 94 0,000 0,03895066 0,03930461 ! sterol metabolic process GO:0016125 166 94 0,000 0,03895066 0,03928838 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,03895066 0,03927216 ! regulation of membrane potential GO:0042391 179 94 0,000 0,03895066 0,03925596 ! regulation of defense response GO:0031347 171 95 0,000 0,03935731 0,03964944 ! nucleosome organization GO:0034728 143 95 0,000 0,03935731 0,0396331 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,03935731 0,03961677 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,03935731 0,03960045 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,03935731 0,03958415 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,03935731 0,03956786 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,03935731 0,03955158 ! sex differentiation GO:0007548 171 96 0,000 0,0397638 0,03994365 ! regulation of T cell activation GO:0050863 175 96 0,000 0,0397638 0,03992723 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,04017012 0,04031866 ! transcription initiation GO:0006352 171 97 0,000 0,04017012 0,0403021 ! regulation of protein localization GO:0032880 188 97 0,000 0,04017012 0,04028556 ! leukocyte differentiation GO:0002521 232 98 0,000 0,04057629 0,04067619 ! forebrain development GO:0030900 210 98 0,000 0,04057629 0,04065951 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,04057629 0,04064284 ! skeletal muscle tissue development GO:0007519 223 100 0,000 0,04138815 0,04143904 GO:0060538|skeletal muscle organ development, ! mRNA transport GO:0051028 185 100 0,000 0,04138815 0,04142206 ! positive regulation of immune response GO:0050778 175 100 0,000 0,04138815 0,0414051 ! hormone metabolic process GO:0042445 171 100 0,000 0,04138815 0,04138815