pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-b1/out-0.05-06-0.01-300-run-b1//th1-pval-1e-01-08-th2-pval-1e-02-02-th3-pval-1e-01-01-run-b1/go_data/253980-3-real-IPC-NIBC-129-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! meiotic chromosome segregation GO:0045132 10 5 1,000 6,418E-06 0,01567831 ! regulation of actin filament polymerization GO:0030833 99 46 2,000 7,239E-06 8,843E-03 ! positive regulation of cell cycle GO:0045787 96 48 2,000 8,239E-06 6,709E-03 ! establishment of spindle localization GO:0051293 16 6 1,000 9,622E-06 5,876E-03 GO:0051653|spindle localization, ! response to exogenous dsRNA GO:0043330 13 6 1,000 9,622E-06 4,701E-03 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 2,000 1,245E-05 5,069E-03 ! regulation of protein polymerization GO:0032271 117 55 2,000 1,245E-05 4,345E-03 ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 1,000 1,346E-05 4,111E-03 ! regulation of actin filament length GO:0030832 118 58 2,000 1,462E-05 3,968E-03 ! regulation of cellular component size GO:0032535 125 61 2,000 1,702E-05 4,159E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 1,794E-05 3,985E-03 ! B cell receptor signaling pathway GO:0050853 22 8 1,000 1,794E-05 3,653E-03 ! regulation of protein complex assembly GO:0043254 132 63 2,000 1,876E-05 3,526E-03 ! regulation of mitosis GO:0007088 112 63 2,000 1,876E-05 3,274E-03 GO:0051783|regulation of nuclear division, ! pyrimidine base metabolic process GO:0006206 22 9 1,000 2,306E-05 3,755E-03 ! response to dsRNA GO:0043331 23 10 1,000 2,881E-05 4,398E-03 ! regulation of actin cytoskeleton organization GO:0032956 167 76 2,000 3,298E-05 4,739E-03 ! T cell receptor signaling pathway GO:0050852 29 11 1,000 3,519E-05 4,776E-03 ! regulation of actin filament-based process GO:0032970 170 79 2,000 3,704E-05 4,762E-03 ! meiosis GO:0007126 143 81 2,000 3,991E-05 4,876E-03 GO:0051327|M phase of meiotic cell cycle, ! meiotic cell cycle GO:0051321 144 82 2,000 4,141E-05 4,817E-03 ! regulation of cell cycle process GO:0010564 161 90 2,000 5,469E-05 6,073E-03 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 1,000 7,658E-05 8,135E-03 ! negative regulation of cell cycle process GO:0010948 35 17 1,000 8,675E-05 8,831E-03 ! nucleobase metabolic process GO:0009112 43 17 1,000 8,675E-05 8,477E-03 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 1,000 8,675E-05 8,151E-03 ! response to lipopolysaccharide GO:0032496 34 19 1,000 1,09E-04 9,859E-03 ! cellular response to unfolded protein GO:0034620 35 20 1,000 1,21E-04 0,01055835 GO:0030968|endoplasmic reticulum unfolded protein response, ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 1,000 1,47E-04 0,01238155 ! response to molecule of bacterial origin GO:0002237 40 23 1,000 1,609E-04 0,01310208 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 1,000 1,754E-04 0,01382511 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 2,064E-04 0,01575488 ! positive regulation of nuclear division GO:0051785 41 26 1,000 2,064E-04 0,01527746 GO:0045840|positive regulation of mitosis, ! regulation of chromosome organization GO:0033044 49 27 1,000 2,228E-04 0,01600627 ! fat cell differentiation GO:0045444 57 28 1,000 2,398E-04 0,01673655 ! base-excision repair GO:0006284 41 28 1,000 2,398E-04 0,01627164 ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 2,574E-04 0,016996 ! immune response-activating signal transduction GO:0002757 58 30 1,000 2,757E-04 0,01772182 GO:0002764|immune response-regulating signal transduction, ! spindle organization GO:0007051 50 32 1,000 3,14E-04 0,01966891 ! mitotic sister chromatid segregation GO:0000070 63 36 1,000 3,98E-04 0,02430888 ! sister chromatid segregation GO:0000819 65 37 1,000 4,205E-04 0,0250585 ! meiosis I GO:0007127 74 38 1,000 4,437E-04 0,0258078 ! cytokinesis GO:0000910 84 42 1,000 5,423E-04 0,03081066 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 1,000 6,506E-04 0,03612231 ! response to calcium ion GO:0051592 94 49 1,000 7,381E-04 0,04007043 ! response to UV GO:0009411 120 55 1,000 9,292E-04 0,04934925 ! regulation of DNA replication GO:0006275 105 56 1,000 9,631E-04 0,05006282 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 1,000 9,977E-04 0,05077671 ! nucleotide-excision repair GO:0006289 91 57 1,000 9,977E-04 0,04974045 ! positive regulation of organelle organization GO:0010638 108 58 1,000 1,033E-03 0,05046105 ! establishment of organelle localization GO:0051656 122 59 1,000 1,068E-03 0,05118159 ! chromosome segregation GO:0007059 127 67 1,000 1,375E-03 0,06460467 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 1,000 1,416E-03 0,06527351 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 1,000 1,458E-03 0,0659438 ! activation of immune response GO:0002253 120 70 1,000 1,5E-03 0,06661542 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 1,000 1,586E-03 0,06917584 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 1,000 1,586E-03 0,06796223 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 1,000 1,674E-03 0,07050819 ! organelle localization GO:0051640 155 74 1,000 1,674E-03 0,06931313 ! phosphoinositide-mediated signaling GO:0048015 141 75 1,000 1,719E-03 0,0699899 ! positive regulation of ligase activity GO:0051351 130 77 1,000 1,811E-03 0,07251527 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 1,000 1,905E-03 0,07504926 ! negative regulation of organelle organization GO:0010639 181 80 1,000 1,952E-03 0,07571356 ! positive regulation of phosphorylation GO:0042327 149 81 1,000 2,001E-03 0,07637881 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 2,099E-03 0,07890744 GO:0045937|positive regulation of phosphate metabolic process, ! response to metal ion GO:0010038 158 84 1,000 2,15E-03 0,07956711 ! regulation of ligase activity GO:0051340 147 84 1,000 2,15E-03 0,07837954 ! response to inorganic substance GO:0010035 173 90 1,000 2,462E-03 0,08845624 ! positive regulation of protein modification process GO:0031401 156 90 1,000 2,462E-03 0,08717427 ! response to unfolded protein GO:0006986 139 90 1,000 2,462E-03 0,08592892 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 1,000 2,626E-03 0,09035659 GO:0010498|proteasomal protein catabolic process, ! response to protein stimulus GO:0051789 158 96 1,000 2,795E-03 0,09483144 ! regulation of DNA metabolic process GO:0051052 188 97 1,000 2,852E-03 0,09545331 ! interphase of mitotic cell cycle GO:0051329 224 98 1,000 2,91E-03 0,09607665 ! positive regulation of immune response GO:0050778 175 100 1,000 3,028E-03 0,09862511 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 4,073E-03 0,13092642 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 4,073E-03 0,12922608 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 4,073E-03 0,12756934 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 4,073E-03 0,12595453 ! positive regulation of helicase activity GO:0051096 12 5 0,000 4,073E-03 0,1243801 ! neuron fate determination GO:0048664 7 5 0,000 4,073E-03 0,12284454 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 4,073E-03 0,12134644 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 4,073E-03 0,11988444 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 4,073E-03 0,11845724 ! polyol transport GO:0015791 12 5 0,000 4,073E-03 0,11706363 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 4,073E-03 0,11570242 ! response to superoxide GO:0000303 10 5 0,000 4,073E-03 0,11437251 ! negative regulation of bone resorption GO:0045779 10 5 0,000 4,073E-03 0,11307282 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 4,073E-03 0,11180234 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 4,073E-03 0,11056009 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 4,073E-03 0,10934514 ! female meiosis GO:0007143 10 5 0,000 4,073E-03 0,10815661 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 4,073E-03 0,10699364 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 4,073E-03 0,10585541 ! hypothalamus development GO:0021854 9 5 0,000 4,073E-03 0,10474114 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 4,073E-03 0,10365008 ! cobalt ion transport GO:0006824 11 5 0,000 4,073E-03 0,10258153 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 4,073E-03 0,10153478 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 4,073E-03 0,10050917 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 4,073E-03 0,09950408 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 4,073E-03 0,09851889 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 4,073E-03 0,09755302 ! embryonic camera-type eye development GO:0031076 12 5 0,000 4,073E-03 0,0966059 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 4,073E-03 0,095677 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 4,073E-03 0,09476579 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 4,073E-03 0,09387177 ! transposition GO:0032196 9 5 0,000 4,073E-03 0,09299447 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 4,073E-03 0,09213341 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 4,073E-03 0,09128815 ! negative chemotaxis GO:0050919 16 5 0,000 4,073E-03 0,09045826 ! positive regulation of histone modification GO:0031058 6 5 0,000 4,073E-03 0,08964332 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 4,073E-03 0,08884293 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 4,073E-03 0,08805671 ! behavioral response to pain GO:0048266 10 5 0,000 4,073E-03 0,08728428 ! clathrin coat assembly GO:0048268 15 5 0,000 4,073E-03 0,08652529 ! Notch receptor processing GO:0007220 11 5 0,000 4,073E-03 0,08577938 ! regulation of dopamine uptake GO:0051584 9 5 0,000 4,073E-03 0,08504622 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 4,073E-03 0,08432549 ! micturition GO:0060073 9 5 0,000 4,073E-03 0,08361688 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 4,073E-03 0,08292007 ! copulation GO:0007620 9 5 0,000 4,073E-03 0,08223478 ! glial cell fate commitment GO:0021781 14 5 0,000 4,073E-03 0,08156072 ! protein maturation by protein folding GO:0022417 14 5 0,000 4,073E-03 0,08089763 ! bioluminescence GO:0008218 9 5 0,000 4,073E-03 0,08024523 ! spermidine metabolic process GO:0008216 7 5 0,000 4,073E-03 0,07960327 ! regulation of potassium ion transport GO:0043266 10 5 0,000 4,073E-03 0,07897149 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 4,073E-03 0,07834967 ! apoptotic cell clearance GO:0043277 23 5 0,000 4,073E-03 0,07773756 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 4,073E-03 0,07713495 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 4,073E-03 0,0765416 ! lipoprotein particle clearance GO:0034381 10 5 0,000 4,073E-03 0,07595731 ! grooming behavior GO:0007625 6 5 0,000 4,073E-03 0,07538188 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 4,073E-03 0,0748151 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 4,073E-03 0,07425678 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 4,073E-03 0,07370673 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 4,073E-03 0,07316477 ! response to protozoan GO:0001562 13 5 0,000 4,073E-03 0,07263072 ! positive regulation of glycolysis GO:0045821 13 5 0,000 4,073E-03 0,07210441 ! lymph vessel development GO:0001945 10 5 0,000 4,073E-03 0,07158567 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 4,073E-03 0,07107434 ! endochondral ossification GO:0001958 17 5 0,000 4,073E-03 0,07057027 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 4,073E-03 0,0700733 ! single strand break repair GO:0000012 8 5 0,000 4,073E-03 0,06958327 ! parathyroid gland development GO:0060017 14 5 0,000 4,073E-03 0,06910006 ! anagen GO:0042640 7 5 0,000 4,073E-03 0,0686235 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 4,073E-03 0,06815348 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 4,073E-03 0,06768985 ! cytokine secretion GO:0050663 15 5 0,000 4,073E-03 0,06723249 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 4,073E-03 0,06678126 ! ceramide catabolic process GO:0046514 7 5 0,000 4,073E-03 0,06633605 ! skeletal myofibril assembly GO:0014866 12 5 0,000 4,073E-03 0,06589674 ! smooth muscle tissue development GO:0048745 32 5 0,000 4,073E-03 0,06546321 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 4,073E-03 0,06503535 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 4,073E-03 0,06461304 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 4,073E-03 0,06419618 ! cardiac muscle fiber development GO:0048739 12 5 0,000 4,073E-03 0,06378467 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 4,073E-03 0,0633784 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 4,073E-03 0,06297727 ! neutrophil mediated immunity GO:0002446 7 5 0,000 4,073E-03 0,06258118 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 4,073E-03 0,06219005 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 4,073E-03 0,06180378 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 4,073E-03 0,06142227 ! glycine biosynthetic process GO:0006545 7 5 0,000 4,073E-03 0,06104545 ! microvillus organization GO:0032528 8 5 0,000 4,073E-03 0,06067322 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 4,073E-03 0,0603055 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 4,073E-03 0,05994222 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 4,073E-03 0,05958328 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 4,073E-03 0,05922862 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 4,073E-03 0,05887815 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 4,073E-03 0,05853181 ! polyol catabolic process GO:0046174 9 5 0,000 4,073E-03 0,05818952 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 4,073E-03 0,05785121 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 4,073E-03 0,05751681 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 4,073E-03 0,05718625 ! muscle cell migration GO:0014812 8 5 0,000 4,073E-03 0,05685948 ! mitochondrial fission GO:0000266 8 5 0,000 4,073E-03 0,05653641 ! sister chromatid cohesion GO:0007062 15 5 0,000 4,073E-03 0,056217 ! response to tumor necrosis factor GO:0034612 10 5 0,000 4,073E-03 0,05590117 ! mRNA transcription GO:0009299 10 5 0,000 4,073E-03 0,05558887 ! nerve growth factor processing GO:0032455 9 5 0,000 4,073E-03 0,05528005 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 4,073E-03 0,05497463 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 4,073E-03 0,05467257 ! anaerobic glycolysis GO:0019642 6 5 0,000 4,073E-03 0,05437381 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 4,073E-03 0,05407831 ! monocyte activation GO:0042117 10 5 0,000 4,073E-03 0,05378599 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 4,073E-03 0,05349682 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 4,073E-03 0,05321074 ! response to food GO:0032094 6 5 0,000 4,073E-03 0,0529277 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 4,073E-03 0,05264766 ! positive regulation of transporter activity GO:0032411 8 5 0,000 4,073E-03 0,05237057 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 4,073E-03 0,05209638 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 4,073E-03 0,05182504 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 4,073E-03 0,05155652 ! forebrain neuron development GO:0021884 13 5 0,000 4,073E-03 0,05129076 ! lipoprotein catabolic process GO:0042159 11 5 0,000 4,073E-03 0,05102773 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 4,073E-03 0,05076739 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 4,073E-03 0,05050969 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 4,073E-03 0,05025459 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 4,073E-03 0,05000205 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 4,073E-03 0,04975204 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 4,073E-03 0,04950452 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 4,073E-03 0,04925945 ! lipid glycosylation GO:0030259 7 5 0,000 4,073E-03 0,04901679 ! nucleobase transport GO:0015851 6 5 0,000 4,073E-03 0,04877651 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 4,073E-03 0,04853858 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 4,073E-03 0,04830295 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 4,073E-03 0,0480696 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 4,073E-03 0,0478385 ! basic amino acid transport GO:0015802 12 5 0,000 4,073E-03 0,04760961 ! cellular glucose homeostasis GO:0001678 6 5 0,000 4,073E-03 0,0473829 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 4,073E-03 0,04715833 ! actin nucleation GO:0045010 11 5 0,000 4,073E-03 0,04693589 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 4,073E-03 0,04671553 ! depurination GO:0045007 5 5 0,000 4,073E-03 0,04649723 ! depyrimidination GO:0045008 10 5 0,000 4,073E-03 0,04628097 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 4,073E-03 0,0460667 ! regulation of centrosome cycle GO:0046605 7 5 0,000 4,073E-03 0,04585442 ! G2/M transition checkpoint GO:0031576 8 5 0,000 4,073E-03 0,04564407 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 4,073E-03 0,04543565 ! zinc ion homeostasis GO:0055069 9 5 0,000 4,073E-03 0,04522913 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 4,073E-03 0,04502447 ! forebrain morphogenesis GO:0048853 13 5 0,000 4,073E-03 0,04482166 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 4,073E-03 0,04462066 ! activated T cell proliferation GO:0050798 16 5 0,000 4,073E-03 0,04442146 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 4,073E-03 0,04422404 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 4,073E-03 0,04402835 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 4,073E-03 0,0438344 ! positive regulation of organ growth GO:0046622 6 5 0,000 4,073E-03 0,04364214 ! gamma-delta T cell activation GO:0046629 6 5 0,000 4,073E-03 0,04345156 ! response to arsenic GO:0046685 11 5 0,000 4,073E-03 0,04326264 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 4,073E-03 0,04307536 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 4,073E-03 0,04288969 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 4,073E-03 0,04270561 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 4,073E-03 0,04252311 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 4,073E-03 0,04234216 ! response to mercury ion GO:0046689 8 5 0,000 4,073E-03 0,04216275 ! response to cadmium ion GO:0046686 7 5 0,000 4,073E-03 0,04198484 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 4,073E-03 0,04180844 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 4,073E-03 0,04163351 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 4,073E-03 0,04146003 ! bile acid biosynthetic process GO:0006699 7 5 0,000 4,073E-03 0,041288 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 4,073E-03 0,04111739 ! ganglioside catabolic process GO:0006689 12 5 0,000 4,073E-03 0,04094818 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 4,073E-03 0,04078036 ! decidualization GO:0046697 11 5 0,000 4,073E-03 0,04061391 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 4,073E-03 0,04044881 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 4,073E-03 0,04028505 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 4,073E-03 0,04012261 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 4,073E-03 0,03996148 ! embryonic cleavage GO:0040016 6 5 0,000 4,073E-03 0,03980163 ! peroxisome fission GO:0016559 5 5 0,000 4,073E-03 0,03964306 ! histone demethylation GO:0016577 13 5 0,000 4,073E-03 0,03948575 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 4,073E-03 0,03932968 ! mitotic recombination GO:0006312 9 5 0,000 4,073E-03 0,03917484 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 4,073E-03 0,03902121 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 4,073E-03 0,03886878 ! metaphase plate congression GO:0051310 7 5 0,000 4,073E-03 0,03871754 ! regulation of sterol transport GO:0032371 7 5 0,000 4,073E-03 0,03856747 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 4,073E-03 0,03841856 ! enteric nervous system development GO:0048484 8 5 0,000 4,073E-03 0,0382708 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 4,073E-03 0,03812417 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 4,073E-03 0,03797866 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 4,073E-03 0,03783425 ! muscle cell proliferation GO:0033002 12 5 0,000 4,073E-03 0,03769094 ! skeletal muscle regeneration GO:0043403 8 5 0,000 4,073E-03 0,03754871 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 4,073E-03 0,03740755 ! B cell homeostasis GO:0001782 13 5 0,000 4,073E-03 0,03726745 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 4,073E-03 0,03712839 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 4,073E-03 0,03699036 ! metaphase GO:0051323 11 5 0,000 4,073E-03 0,03685336 ! melatonin biosynthetic process GO:0030187 7 5 0,000 4,073E-03 0,03671737 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 4,073E-03 0,03658238 ! cellular response to nutrient GO:0031670 8 5 0,000 4,073E-03 0,03644838 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 4,073E-03 0,03631536 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 4,073E-03 0,0361833 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 4,073E-03 0,0360522 ! regulation of hair follicle development GO:0051797 10 5 0,000 4,073E-03 0,03592205 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 4,073E-03 0,03579284 ! response to redox state GO:0051775 6 5 0,000 4,073E-03 0,03566455 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 4,073E-03 0,03553717 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 4,073E-03 0,03541071 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 4,073E-03 0,03528514 ! brown fat cell differentiation GO:0050873 7 5 0,000 4,073E-03 0,03516045 ! regulation of telomerase activity GO:0051972 7 5 0,000 4,073E-03 0,03503665 ! galactolipid metabolic process GO:0019374 7 5 0,000 4,073E-03 0,03491371 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 4,073E-03 0,03479164 ! porphyrin catabolic process GO:0006787 12 5 0,000 4,073E-03 0,03467041 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 4,073E-03 0,03455003 ! striatum development GO:0021756 14 5 0,000 4,073E-03 0,03443048 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 4,073E-03 0,03431175 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 4,073E-03 0,03419384 ! glial cell migration GO:0008347 10 5 0,000 4,073E-03 0,03407674 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 4,073E-03 0,03396044 ! neural plate morphogenesis GO:0001839 7 5 0,000 4,073E-03 0,03384493 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 4,073E-03 0,0337302 ! somatic stem cell maintenance GO:0035019 15 5 0,000 4,073E-03 0,03361624 ! T cell activation during immune response GO:0002286 9 5 0,000 4,073E-03 0,03350306 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 4,073E-03 0,03339063 ! negative regulation of lipase activity GO:0060192 8 5 0,000 4,073E-03 0,03327896 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 4,073E-03 0,03316803 ! neuroprotection GO:0043526 8 5 0,000 4,073E-03 0,03305783 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 4,073E-03 0,03294837 ! regulation of sensory perception GO:0051931 8 5 0,000 4,073E-03 0,03283963 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 4,073E-03 0,03273161 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 4,073E-03 0,03262429 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 4,073E-03 0,03251767 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 4,073E-03 0,03241175 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 4,073E-03 0,03230652 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 4,073E-03 0,03220197 ! sequestering of calcium ion GO:0051208 7 5 0,000 4,073E-03 0,03209809 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 4,073E-03 0,03199488 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 4,073E-03 0,03189233 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 4,073E-03 0,03179044 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 4,073E-03 0,0316892 ! spindle assembly GO:0051225 6 5 0,000 4,073E-03 0,0315886 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 4,073E-03 0,03148863 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 4,073E-03 0,0313893 ! protein palmitoylation GO:0018345 12 5 0,000 4,073E-03 0,03129059 ! drug metabolic process GO:0017144 7 5 0,000 4,073E-03 0,0311925 ! stem cell division GO:0017145 11 5 0,000 4,073E-03 0,03109503 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 4,073E-03 0,03099816 ! organ regeneration GO:0031100 7 5 0,000 4,073E-03 0,03090189 ! carnitine metabolic process GO:0009437 8 5 0,000 4,073E-03 0,03080622 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 4,073E-03 0,03071114 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 4,886E-03 0,0367255 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 4,886E-03 0,03661285 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 4,886E-03 0,03650088 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 4,886E-03 0,0363896 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 4,886E-03 0,03627899 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 4,886E-03 0,03616906 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 4,886E-03 0,03605978 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 4,886E-03 0,03595117 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 4,886E-03 0,03584321 ! response to oxygen radical GO:0000305 11 6 0,000 4,886E-03 0,03573589 ! positive regulation of axon extension GO:0045773 13 6 0,000 4,886E-03 0,03562922 ! myoblast cell fate commitment GO:0048625 18 6 0,000 4,886E-03 0,03552318 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 4,886E-03 0,03541777 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 4,886E-03 0,03531298 ! regulation of interferon-beta production GO:0032648 8 6 0,000 4,886E-03 0,03520882 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 4,886E-03 0,03510526 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 4,886E-03 0,03500231 ! forebrain regionalization GO:0021871 9 6 0,000 4,886E-03 0,03489997 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 4,886E-03 0,03479822 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 4,886E-03 0,03469706 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 4,886E-03 0,03459649 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 4,886E-03 0,0344965 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 4,886E-03 0,03439709 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 4,886E-03 0,03429824 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 4,886E-03 0,03419997 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 4,886E-03 0,03410225 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 4,886E-03 0,0340051 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 4,886E-03 0,03390849 ! malate metabolic process GO:0006108 13 6 0,000 4,886E-03 0,03381243 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 4,886E-03 0,03371692 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 4,886E-03 0,03362194 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 4,886E-03 0,0335275 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 4,886E-03 0,03343358 ! protein refolding GO:0042026 15 6 0,000 4,886E-03 0,03334019 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 4,886E-03 0,03324732 ! opsonization GO:0008228 8 6 0,000 4,886E-03 0,03315497 ! mating behavior GO:0007617 7 6 0,000 4,886E-03 0,03306313 ! erythrocyte maturation GO:0043249 8 6 0,000 4,886E-03 0,03297179 ! embryonic hemopoiesis GO:0035162 16 6 0,000 4,886E-03 0,03288096 ! protein amino acid dealkylation GO:0008214 15 6 0,000 4,886E-03 0,03279063 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 4,886E-03 0,03270079 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 4,886E-03 0,03261144 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 4,886E-03 0,03252258 ! response to interferon-gamma GO:0034341 16 6 0,000 4,886E-03 0,03243421 ! toxin metabolic process GO:0009404 11 6 0,000 4,886E-03 0,03234631 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 4,886E-03 0,03225889 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 4,886E-03 0,03217194 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 4,886E-03 0,03208545 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 4,886E-03 0,03199943 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 4,886E-03 0,03191387 ! cGMP-mediated signaling GO:0019934 14 6 0,000 4,886E-03 0,03182877 ! dorsal spinal cord development GO:0021516 10 6 0,000 4,886E-03 0,03174412 ! activation of MAPKKK activity GO:0000185 12 6 0,000 4,886E-03 0,03165992 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 4,886E-03 0,03157616 ! thymic T cell selection GO:0045061 16 6 0,000 4,886E-03 0,03149285 ! sphingoid catabolic process GO:0046521 8 6 0,000 4,886E-03 0,03140997 ! protein lipoylation GO:0009249 10 6 0,000 4,886E-03 0,03132753 ! transepithelial chloride transport GO:0030321 12 6 0,000 4,886E-03 0,03124552 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 4,886E-03 0,03116394 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 4,886E-03 0,03108278 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 4,886E-03 0,03100205 ! glutamate catabolic process GO:0006538 12 6 0,000 4,886E-03 0,03092173 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 4,886E-03 0,03084183 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 4,886E-03 0,03076234 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 4,886E-03 0,03068326 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 4,886E-03 0,03060459 ! hyperosmotic response GO:0006972 10 6 0,000 4,886E-03 0,03052631 ! L-serine biosynthetic process GO:0006564 7 6 0,000 4,886E-03 0,03044844 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 4,886E-03 0,03037096 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 4,886E-03 0,03029388 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 4,886E-03 0,03021719 ! urea metabolic process GO:0019627 7 6 0,000 4,886E-03 0,03014088 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 4,886E-03 0,03006496 ! neutrophil activation GO:0042119 7 6 0,000 4,886E-03 0,02998942 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 4,886E-03 0,02991426 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 4,886E-03 0,02983947 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 4,886E-03 0,02976506 ! paraxial mesoderm development GO:0048339 16 6 0,000 4,886E-03 0,02969102 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 4,886E-03 0,02961734 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 4,886E-03 0,02954403 ! neuron apoptosis GO:0051402 15 6 0,000 4,886E-03 0,02947108 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 4,886E-03 0,02939849 ! T cell mediated immunity GO:0002456 17 6 0,000 4,886E-03 0,02932626 ! negative regulation of platelet activation GO:0010544 9 6 0,000 4,886E-03 0,02925438 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 4,886E-03 0,02918286 ! carnitine transport GO:0015879 10 6 0,000 4,886E-03 0,02911168 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 4,886E-03 0,02904085 ! positive regulation of exocytosis GO:0045921 11 6 0,000 4,886E-03 0,02897036 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 4,886E-03 0,02890021 ! early endosome to late endosome transport GO:0045022 16 6 0,000 4,886E-03 0,02883041 ! 5S class rRNA transcription GO:0042791 13 6 0,000 4,886E-03 0,02876094 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 4,886E-03 0,0286918 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 4,886E-03 0,02862299 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 4,886E-03 0,02855452 ! sodium ion homeostasis GO:0055078 12 6 0,000 4,886E-03 0,02848637 ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 4,886E-03 0,02841854 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 4,886E-03 0,02835104 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 4,886E-03 0,02828386 ! response to UV-C GO:0010225 14 6 0,000 4,886E-03 0,02821699 ! astrocyte development GO:0014002 16 6 0,000 4,886E-03 0,02815044 ! protein targeting to lysosome GO:0006622 12 6 0,000 4,886E-03 0,02808421 ! purine base biosynthetic process GO:0009113 17 6 0,000 4,886E-03 0,02801828 ! interaction with symbiont GO:0051702 14 6 0,000 4,886E-03 0,02795267 ! regulation of dendrite development GO:0050773 16 6 0,000 4,886E-03 0,02788736 ! peptidyl-arginine modification GO:0018195 13 6 0,000 4,886E-03 0,02782235 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 4,886E-03 0,02775765 ! response to copper ion GO:0046688 10 6 0,000 4,886E-03 0,02769325 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 4,886E-03 0,02762914 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 4,886E-03 0,02756533 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 4,886E-03 0,02750182 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 4,886E-03 0,02743859 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 4,886E-03 0,02737566 ! regulation of dopamine secretion GO:0014059 14 6 0,000 4,886E-03 0,02731302 ! nucleoside catabolic process GO:0009164 10 6 0,000 4,886E-03 0,02725066 ! hair follicle maturation GO:0048820 8 6 0,000 4,886E-03 0,02718858 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 4,886E-03 0,02712679 ! Schwann cell development GO:0014044 15 6 0,000 4,886E-03 0,02706528 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 4,886E-03 0,02700405 ! response to pheromone GO:0019236 6 6 0,000 4,886E-03 0,02694309 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 4,886E-03 0,02688241 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 4,886E-03 0,026822 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 4,886E-03 0,02676186 ! base conversion or substitution editing GO:0016553 6 6 0,000 4,886E-03 0,02670199 ! subpallium development GO:0021544 15 6 0,000 4,886E-03 0,02664239 ! neural tube patterning GO:0021532 8 6 0,000 4,886E-03 0,02658305 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 4,886E-03 0,02652397 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 4,886E-03 0,02646516 ! maintenance of organ identity GO:0048496 9 6 0,000 4,886E-03 0,02640661 ! G2 phase GO:0051319 16 6 0,000 4,886E-03 0,02634832 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 4,886E-03 0,02629028 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 4,886E-03 0,0262325 ! oxygen homeostasis GO:0032364 10 6 0,000 4,886E-03 0,02617498 ! establishment of planar polarity GO:0001736 7 6 0,000 4,886E-03 0,0261177 ! regulation of mast cell activation GO:0033003 13 6 0,000 4,886E-03 0,02606067 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 4,886E-03 0,0260039 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 4,886E-03 0,02594737 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 4,886E-03 0,02589108 ! receptor internalization GO:0031623 11 6 0,000 4,886E-03 0,02583504 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 4,886E-03 0,02577924 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 4,886E-03 0,02572368 ! neutrophil homeostasis GO:0001780 11 6 0,000 4,886E-03 0,02566836 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 4,886E-03 0,02561328 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 4,886E-03 0,02555843 ! protein deubiquitination GO:0016579 16 6 0,000 4,886E-03 0,02550382 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 4,886E-03 0,02544944 ! protein destabilization GO:0031648 9 6 0,000 4,886E-03 0,02539529 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 4,886E-03 0,02534138 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 4,886E-03 0,02528769 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 4,886E-03 0,02523423 ! regulation of viral transcription GO:0046782 11 6 0,000 4,886E-03 0,02518099 ! progesterone metabolic process GO:0042448 12 6 0,000 4,886E-03 0,02512798 ! negative regulation of axon extension GO:0030517 24 6 0,000 4,886E-03 0,02507519 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 4,886E-03 0,02502262 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 4,886E-03 0,02497027 ! triglyceride catabolic process GO:0019433 10 6 0,000 4,886E-03 0,02491814 ! determination of adult lifespan GO:0008340 17 6 0,000 4,886E-03 0,02486623 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 4,886E-03 0,02481453 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 4,886E-03 0,02476305 ! neural plate development GO:0001840 9 6 0,000 4,886E-03 0,02471178 ! catecholamine transport GO:0051937 9 6 0,000 4,886E-03 0,02466072 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 4,886E-03 0,02460987 ! sensory cilium assembly GO:0035058 10 6 0,000 4,886E-03 0,02455924 ! organ or tissue specific immune response GO:0002251 8 6 0,000 4,886E-03 0,02450881 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 4,886E-03 0,02445858 ! maternal placenta development GO:0001893 12 6 0,000 4,886E-03 0,02440857 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 4,886E-03 0,02435875 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 4,886E-03 0,02430914 ! negative regulation of B cell activation GO:0050869 14 6 0,000 4,886E-03 0,02425973 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 4,886E-03 0,02421052 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 4,886E-03 0,02416152 ! positive regulation of coagulation GO:0050820 13 6 0,000 4,886E-03 0,0241127 ! cellular anion homeostasis GO:0030002 11 6 0,000 4,886E-03 0,02406409 GO:0055081|anion homeostasis, ! tRNA transcription GO:0009304 17 7 0,000 5,698E-03 0,02800725 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 5,698E-03 0,02795101 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 5,698E-03 0,027895 ! behavioral response to cocaine GO:0048148 14 7 0,000 5,698E-03 0,02783921 ! regulation of helicase activity GO:0051095 16 7 0,000 5,698E-03 0,02778364 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 5,698E-03 0,0277283 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 5,698E-03 0,02767317 ! sleep GO:0030431 16 7 0,000 5,698E-03 0,02761826 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 5,698E-03 0,02756357 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 5,698E-03 0,0275091 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 5,698E-03 0,02745484 ! prostate gland development GO:0030850 14 7 0,000 5,698E-03 0,0274008 ! nucleotide-sugar transport GO:0015780 11 7 0,000 5,698E-03 0,02734696 ! synaptonemal complex assembly GO:0007130 10 7 0,000 5,698E-03 0,02729334 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 5,698E-03 0,02723993 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 5,698E-03 0,02718673 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 5,698E-03 0,02713373 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 5,698E-03 0,02708094 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 5,698E-03 0,02702836 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 5,698E-03 0,02697598 ! SMAD protein complex assembly GO:0007183 13 7 0,000 5,698E-03 0,0269238 ! glycolipid transport GO:0046836 11 7 0,000 5,698E-03 0,02687182 ! protein amino acid sulfation GO:0006477 10 7 0,000 5,698E-03 0,02682005 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 5,698E-03 0,02676847 ! neuron adhesion GO:0007158 14 7 0,000 5,698E-03 0,02671709 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 5,698E-03 0,02666591 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 5,698E-03 0,02661492 ! establishment of tissue polarity GO:0007164 8 7 0,000 5,698E-03 0,02656413 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 5,698E-03 0,02651353 ! mRNA stabilization GO:0048255 18 7 0,000 5,698E-03 0,02646313 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 5,698E-03 0,02641291 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 5,698E-03 0,02636289 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 5,698E-03 0,02631305 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 5,698E-03 0,02626341 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 5,698E-03 0,02621395 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 5,698E-03 0,02616467 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 5,698E-03 0,02611558 ! lipoprotein transport GO:0042953 14 7 0,000 5,698E-03 0,02606668 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 5,698E-03 0,02601795 ! rhythmic behavior GO:0007622 17 7 0,000 5,698E-03 0,02596941 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 5,698E-03 0,02592105 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 5,698E-03 0,02587287 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 5,698E-03 0,02582487 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 5,698E-03 0,02577705 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 5,698E-03 0,0257294 ! regulation of odontogenesis GO:0042481 14 7 0,000 5,698E-03 0,02568193 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 5,698E-03 0,02563463 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 5,698E-03 0,02558751 ! mechanosensory behavior GO:0007638 16 7 0,000 5,698E-03 0,02554056 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 5,698E-03 0,02549378 ! positive regulation of isotype switching GO:0045830 17 7 0,000 5,698E-03 0,02544718 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 5,698E-03 0,02540074 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 5,698E-03 0,02535447 ! protein-cofactor linkage GO:0018065 13 7 0,000 5,698E-03 0,02530837 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 5,698E-03 0,02526244 ! spinal cord patterning GO:0021511 14 7 0,000 5,698E-03 0,02521668 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 5,698E-03 0,02517108 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 5,698E-03 0,02512564 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 5,698E-03 0,02508037 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 5,698E-03 0,02503526 ! adrenal gland development GO:0030325 17 7 0,000 5,698E-03 0,02499031 ! cysteine metabolic process GO:0006534 13 7 0,000 5,698E-03 0,02494553 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 5,698E-03 0,0249009 ! ovulation GO:0030728 10 7 0,000 5,698E-03 0,02485644 ! adenohypophysis development GO:0021984 11 7 0,000 5,698E-03 0,02481213 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 5,698E-03 0,02476798 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 5,698E-03 0,02472399 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 5,698E-03 0,02468015 ! microtubule nucleation GO:0007020 21 7 0,000 5,698E-03 0,02463647 ! proline biosynthetic process GO:0006561 10 7 0,000 5,698E-03 0,02459294 ! tryptophan metabolic process GO:0006568 11 7 0,000 5,698E-03 0,02454957 ! thyroid hormone generation GO:0006590 13 7 0,000 5,698E-03 0,02450635 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 5,698E-03 0,02446328 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 5,698E-03 0,02442036 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 5,698E-03 0,02437759 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 5,698E-03 0,02433497 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 5,698E-03 0,0242925 ! galactose metabolic process GO:0006012 13 7 0,000 5,698E-03 0,02425018 ! vesicle fusion GO:0006906 20 7 0,000 5,698E-03 0,02420801 ! response to dietary excess GO:0002021 8 7 0,000 5,698E-03 0,02416598 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 5,698E-03 0,0241241 ! intracellular pH reduction GO:0051452 13 7 0,000 5,698E-03 0,02408236 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 5,698E-03 0,02404077 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 5,698E-03 0,02399932 ! organ growth GO:0035265 15 7 0,000 5,698E-03 0,02395801 ! nucleoside transport GO:0015858 11 7 0,000 5,698E-03 0,02391685 ! nucleoside salvage GO:0043174 11 7 0,000 5,698E-03 0,02387582 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 5,698E-03 0,02383494 ! male sex determination GO:0030238 15 7 0,000 5,698E-03 0,0237942 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 5,698E-03 0,02375359 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 5,698E-03 0,02371313 ! parturition GO:0007567 16 7 0,000 5,698E-03 0,0236728 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 5,698E-03 0,02363261 ! rRNA modification GO:0000154 14 7 0,000 5,698E-03 0,02359255 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 5,698E-03 0,02355263 ! spindle checkpoint GO:0031577 16 7 0,000 5,698E-03 0,02351285 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 5,698E-03 0,0234732 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 5,698E-03 0,02343368 ! monocyte differentiation GO:0030224 16 7 0,000 5,698E-03 0,02339429 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 5,698E-03 0,02335504 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 5,698E-03 0,02331592 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 5,698E-03 0,02327693 ! hyaluronan metabolic process GO:0030212 9 7 0,000 5,698E-03 0,02323807 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 5,698E-03 0,02319934 ! anterograde axon cargo transport GO:0008089 18 7 0,000 5,698E-03 0,02316074 ! fibrinolysis GO:0042730 11 7 0,000 5,698E-03 0,02312227 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 5,698E-03 0,02308392 ! skeletal muscle contraction GO:0003009 8 7 0,000 5,698E-03 0,0230457 ! eating behavior GO:0042755 8 7 0,000 5,698E-03 0,02300761 ! B cell lineage commitment GO:0002326 21 7 0,000 5,698E-03 0,02296965 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 5,698E-03 0,0229318 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 5,698E-03 0,02289409 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 5,698E-03 0,02285649 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 5,698E-03 0,02281902 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 5,698E-03 0,02278168 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 5,698E-03 0,02274445 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 5,698E-03 0,02270735 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 5,698E-03 0,02267037 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 5,698E-03 0,0226335 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 5,698E-03 0,02259676 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 5,698E-03 0,02256014 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 5,698E-03 0,02252363 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 5,698E-03 0,02248725 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 5,698E-03 0,02245098 ! histone ubiquitination GO:0016574 9 7 0,000 5,698E-03 0,02241482 ! regulation of meiosis GO:0040020 12 7 0,000 5,698E-03 0,02237879 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 5,698E-03 0,02234287 ! T cell lineage commitment GO:0002360 16 7 0,000 5,698E-03 0,02230706 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 5,698E-03 0,02227137 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 5,698E-03 0,02223579 ! membrane to membrane docking GO:0022614 14 7 0,000 5,698E-03 0,02220033 ! transcription termination GO:0006353 14 7 0,000 5,698E-03 0,02216498 ! coenzyme A metabolic process GO:0015936 12 7 0,000 5,698E-03 0,02212974 ! anaphase GO:0051322 18 7 0,000 5,698E-03 0,02209461 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 5,698E-03 0,0220596 ! axonal fasciculation GO:0007413 19 7 0,000 5,698E-03 0,02202469 ! negative regulation of nuclear division GO:0051784 15 7 0,000 5,698E-03 0,0219899 GO:0045839|negative regulation of mitosis, ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 5,698E-03 0,02195521 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 5,698E-03 0,02192064 ! diuresis GO:0030146 12 7 0,000 5,698E-03 0,02188617 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 5,698E-03 0,02185181 ! thiamin metabolic process GO:0006772 7 7 0,000 5,698E-03 0,02181756 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 5,698E-03 0,02178342 ! antibiotic transport GO:0042891 9 7 0,000 5,698E-03 0,02174938 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 5,698E-03 0,02171545 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 5,698E-03 0,02168163 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 5,698E-03 0,02164791 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 5,698E-03 0,02161429 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 5,698E-03 0,02158078 ! melanin biosynthetic process GO:0042438 10 7 0,000 5,698E-03 0,02154738 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 5,698E-03 0,02151407 ! dopamine biosynthetic process GO:0042416 18 7 0,000 5,698E-03 0,02148087 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 5,698E-03 0,02144777 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 5,698E-03 0,02141478 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 5,698E-03 0,02138188 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 5,698E-03 0,02134909 ! endosome to lysosome transport GO:0008333 12 7 0,000 5,698E-03 0,02131639 ! protein modification by small protein removal GO:0070646 19 7 0,000 5,698E-03 0,0212838 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 5,698E-03 0,02125131 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 5,698E-03 0,02121891 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 5,698E-03 0,02118661 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 5,698E-03 0,02115441 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 5,698E-03 0,02112231 ! muscle adaptation GO:0043500 13 7 0,000 5,698E-03 0,02109031 ! embryonic heart tube development GO:0035050 14 7 0,000 5,698E-03 0,0210584 ! retina homeostasis GO:0001895 12 7 0,000 5,698E-03 0,02102659 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 5,698E-03 0,02099488 ! protein amino acid prenylation GO:0018346 19 7 0,000 5,698E-03 0,02096326 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 5,698E-03 0,02093174 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 5,698E-03 0,02090031 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 6,509E-03 0,02384087 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 6,509E-03 0,02380518 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 6,509E-03 0,02376959 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 6,509E-03 0,02373412 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 6,509E-03 0,02369875 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 6,509E-03 0,02366348 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 6,509E-03 0,02362832 ! male meiosis GO:0007140 9 8 0,000 6,509E-03 0,02359326 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 6,509E-03 0,02355831 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 6,509E-03 0,02352346 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 6,509E-03 0,02348871 ! meiotic prophase I GO:0007128 14 8 0,000 6,509E-03 0,02345407 ! response to zinc ion GO:0010043 12 8 0,000 6,509E-03 0,02341953 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 6,509E-03 0,02338509 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 6,509E-03 0,02335075 ! oligopeptide transport GO:0006857 16 8 0,000 6,509E-03 0,02331651 ! actin-myosin filament sliding GO:0033275 13 8 0,000 6,509E-03 0,02328237 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 6,509E-03 0,02324833 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 6,509E-03 0,02321439 ! signal peptide processing GO:0006465 12 8 0,000 6,509E-03 0,02318055 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 6,509E-03 0,02314681 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 6,509E-03 0,02311317 ! macrophage chemotaxis GO:0048246 12 8 0,000 6,509E-03 0,02307962 ! succinate metabolic process GO:0006105 17 8 0,000 6,509E-03 0,02304617 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 6,509E-03 0,02301282 ! membrane hyperpolarization GO:0060081 11 8 0,000 6,509E-03 0,02297956 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 6,509E-03 0,0229464 ! estrogen metabolic process GO:0008210 17 8 0,000 6,509E-03 0,02291334 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 6,509E-03 0,02288037 ! T-helper 1 type immune response GO:0042088 12 8 0,000 6,509E-03 0,0228475 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 6,509E-03 0,02281472 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 6,509E-03 0,02278203 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 6,509E-03 0,02274944 ! reflex GO:0060004 17 8 0,000 6,509E-03 0,02271694 ! endothelial cell differentiation GO:0045446 17 8 0,000 6,509E-03 0,02268453 ! glycerolipid catabolic process GO:0046503 14 8 0,000 6,509E-03 0,02265222 ! hemoglobin metabolic process GO:0020027 14 8 0,000 6,509E-03 0,02262 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 6,509E-03 0,02258787 ! pigment granule organization GO:0048753 17 8 0,000 6,509E-03 0,02255583 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 6,509E-03 0,02252388 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 6,509E-03 0,02249202 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 6,509E-03 0,02246025 ! astrocyte differentiation GO:0048708 19 8 0,000 6,509E-03 0,02242857 ! histidine catabolic process GO:0006548 10 8 0,000 6,509E-03 0,02239698 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 6,509E-03 0,02236548 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 6,509E-03 0,02233407 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 6,509E-03 0,02230275 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 6,509E-03 0,02227151 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 6,509E-03 0,02224036 ! regulation of pigmentation during development GO:0048070 25 8 0,000 6,509E-03 0,0222093 ! melanin metabolic process GO:0006582 17 8 0,000 6,509E-03 0,02217832 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 6,509E-03 0,02214743 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 6,509E-03 0,02211663 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 6,509E-03 0,02208591 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 6,509E-03 0,02205528 ! macrophage activation GO:0042116 13 8 0,000 6,509E-03 0,02202473 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 6,509E-03 0,02199427 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 6,509E-03 0,02196389 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 6,509E-03 0,0219336 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 6,509E-03 0,02190339 ! purine salvage GO:0043101 12 8 0,000 6,509E-03 0,02187326 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 6,509E-03 0,02184321 ! regulation of vascular permeability GO:0043114 12 8 0,000 6,509E-03 0,02181325 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 6,509E-03 0,02178337 ! osteoblast development GO:0002076 17 8 0,000 6,509E-03 0,02175357 ! positive regulation of vasodilation GO:0045909 14 8 0,000 6,509E-03 0,02172385 ! negative regulation of translational initiation GO:0045947 12 8 0,000 6,509E-03 0,02169421 ! Schwann cell differentiation GO:0014037 21 8 0,000 6,509E-03 0,02166466 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 6,509E-03 0,02163518 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 6,509E-03 0,02160579 ! response to UV-B GO:0010224 17 8 0,000 6,509E-03 0,02157647 ! protein targeting to vacuole GO:0006623 14 8 0,000 6,509E-03 0,02154723 ! protein retention in ER lumen GO:0006621 14 8 0,000 6,509E-03 0,02151808 ! intermediate filament organization GO:0045109 12 8 0,000 6,509E-03 0,021489 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 6,509E-03 0,02146 ! cellular extravasation GO:0045123 13 8 0,000 6,509E-03 0,02143108 ! cardiac muscle cell development GO:0055013 14 8 0,000 6,509E-03 0,02140223 ! response to antibiotic GO:0046677 11 8 0,000 6,509E-03 0,02137347 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 6,509E-03 0,02134478 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 6,509E-03 0,02131616 ! DNA topological change GO:0006265 12 8 0,000 6,509E-03 0,02128763 ! response to tropane GO:0014073 15 8 0,000 6,509E-03 0,02125917 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 6,509E-03 0,02123079 ! melanosome transport GO:0032402 13 8 0,000 6,509E-03 0,02120248 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 0,000 6,509E-03 0,02117425 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 6,509E-03 0,02114609 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 6,509E-03 0,02111801 ! mast cell activation GO:0045576 14 8 0,000 6,509E-03 0,02109 ! multicellular organismal aging GO:0010259 20 8 0,000 6,509E-03 0,02106206 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 6,509E-03 0,0210342 ! gas homeostasis GO:0033483 14 8 0,000 6,509E-03 0,02100642 ! dendrite morphogenesis GO:0048813 14 8 0,000 6,509E-03 0,0209787 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 6,509E-03 0,02095106 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 6,509E-03 0,0209235 ! nucleosome disassembly GO:0006337 14 8 0,000 6,509E-03 0,020896 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 6,509E-03 0,02086858 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 6,509E-03 0,02084123 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 6,509E-03 0,02081395 ! establishment of chromosome localization GO:0051303 14 8 0,000 6,509E-03 0,02078674 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 6,509E-03 0,02075961 ! intracellular lipid transport GO:0032365 16 8 0,000 6,509E-03 0,02073254 ! response to tumor cell GO:0002347 16 8 0,000 6,509E-03 0,02070554 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 6,509E-03 0,02067862 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 6,509E-03 0,02065176 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 6,509E-03 0,02062498 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 6,509E-03 0,02059826 ! positive regulation of epidermis development GO:0045684 13 8 0,000 6,509E-03 0,02057161 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 6,509E-03 0,02054504 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 6,509E-03 0,02051853 ! hormone catabolic process GO:0042447 17 8 0,000 6,509E-03 0,02049209 ! glycolipid catabolic process GO:0019377 16 8 0,000 6,509E-03 0,02046571 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 6,509E-03 0,02043941 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 6,509E-03 0,02041317 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 6,509E-03 0,020387 ! positive regulation of glucose import GO:0046326 8 8 0,000 6,509E-03 0,02036089 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 6,509E-03 0,02033486 ! adult feeding behavior GO:0008343 10 8 0,000 6,509E-03 0,02030889 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 6,509E-03 0,02028298 ! ATP catabolic process GO:0006200 11 8 0,000 6,509E-03 0,02025714 ! blastocyst growth GO:0001832 19 8 0,000 6,509E-03 0,02023137 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 6,509E-03 0,02020566 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 6,509E-03 0,02018002 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 6,509E-03 0,02015445 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 6,509E-03 0,02012893 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 6,509E-03 0,02010349 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 6,509E-03 0,0200781 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 6,509E-03 0,02005278 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 6,509E-03 0,02002753 ! amino sugar catabolic process GO:0046348 11 8 0,000 6,509E-03 0,02000234 GO:0006043|glucosamine catabolic process, ! regulation of growth hormone secretion GO:0060123 16 8 0,000 6,509E-03 0,01997721 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 6,509E-03 0,01995214 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 6,509E-03 0,01992714 ! behavioral response to nicotine GO:0035095 12 8 0,000 6,509E-03 0,0199022 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 6,509E-03 0,01987732 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 6,509E-03 0,01985251 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 6,509E-03 0,01982775 ! NAD biosynthetic process GO:0009435 17 8 0,000 6,509E-03 0,01980306 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 6,509E-03 0,01977843 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 6,509E-03 0,01975386 ! axon extension GO:0048675 16 9 0,000 7,32E-03 0,02218679 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 7,32E-03 0,02215929 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 7,32E-03 0,02213187 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 7,32E-03 0,02210451 ! pentose-phosphate shunt GO:0006098 16 9 0,000 7,32E-03 0,02207722 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 7,32E-03 0,02205 ! cell proliferation in forebrain GO:0021846 18 9 0,000 7,32E-03 0,02202284 ! neutral lipid catabolic process GO:0046461 14 9 0,000 7,32E-03 0,02199576 ! reproductive behavior GO:0019098 22 9 0,000 7,32E-03 0,02196873 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 7,32E-03 0,02194178 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 7,32E-03 0,02191489 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 7,32E-03 0,02188807 ! UTP metabolic process GO:0046051 10 9 0,000 7,32E-03 0,02186131 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 7,32E-03 0,02183461 ! induction of positive chemotaxis GO:0050930 17 9 0,000 7,32E-03 0,02180799 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 7,32E-03 0,02178142 ! artery development GO:0060840 25 9 0,000 7,32E-03 0,02175493 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 7,32E-03 0,02172849 ! regulation of glycolysis GO:0006110 20 9 0,000 7,32E-03 0,02170212 ! cerebral cortex cell migration GO:0021795 18 9 0,000 7,32E-03 0,02167582 ! equilibrioception GO:0050957 20 9 0,000 7,32E-03 0,02164958 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 7,32E-03 0,0216234 ! chemosensory behavior GO:0007635 21 9 0,000 7,32E-03 0,02159728 ! microtubule bundle formation GO:0001578 22 9 0,000 7,32E-03 0,02157123 ! middle ear morphogenesis GO:0042474 14 9 0,000 7,32E-03 0,02154524 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 7,32E-03 0,02151931 ! leukocyte degranulation GO:0043299 16 9 0,000 7,32E-03 0,02149345 ! ganglioside metabolic process GO:0001573 22 9 0,000 7,32E-03 0,02146765 ! negative regulation of endocytosis GO:0045806 12 9 0,000 7,32E-03 0,02144191 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 7,32E-03 0,02141623 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 7,32E-03 0,02139061 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 7,32E-03 0,02136505 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 7,32E-03 0,02133956 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 7,32E-03 0,02131412 ! protein targeting to ER GO:0045047 25 9 0,000 7,32E-03 0,02128875 ! ceramide biosynthetic process GO:0046513 20 9 0,000 7,32E-03 0,02126344 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 7,32E-03 0,02123818 ! T cell selection GO:0045058 27 9 0,000 7,32E-03 0,02121299 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 0,000 7,32E-03 0,02118785 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 7,32E-03 0,02116278 ! glycine catabolic process GO:0006546 15 9 0,000 7,32E-03 0,02113777 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 7,32E-03 0,02111281 ! endosome organization GO:0007032 20 9 0,000 7,32E-03 0,02108791 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 7,32E-03 0,02106307 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 7,32E-03 0,02103829 ! regulation of type I interferon production GO:0032479 12 9 0,000 7,32E-03 0,02101357 ! mannose metabolic process GO:0006013 13 9 0,000 7,32E-03 0,02098891 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 7,32E-03 0,0209643 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 7,32E-03 0,02093975 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 7,32E-03 0,02091526 ! Rac protein signal transduction GO:0016601 20 9 0,000 7,32E-03 0,02089083 ! receptor clustering GO:0043113 20 9 0,000 7,32E-03 0,02086645 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 7,32E-03 0,02084213 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 7,32E-03 0,02081787 ! retinol metabolic process GO:0042572 20 9 0,000 7,32E-03 0,02079366 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 7,32E-03 0,02076951 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 7,32E-03 0,02074542 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 7,32E-03 0,02072138 ! macrophage differentiation GO:0030225 15 9 0,000 7,32E-03 0,0206974 ! oligodendrocyte development GO:0014003 11 9 0,000 7,32E-03 0,02067347 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 7,32E-03 0,0206496 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 7,32E-03 0,02062578 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 7,32E-03 0,02060202 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 7,32E-03 0,02057831 ! response to amine stimulus GO:0014075 13 9 0,000 7,32E-03 0,02055465 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 7,32E-03 0,02053106 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 7,32E-03 0,02050751 ! erythrocyte development GO:0048821 17 9 0,000 7,32E-03 0,02048402 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 7,32E-03 0,02046058 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 7,32E-03 0,0204372 ! renal water homeostasis GO:0003091 15 9 0,000 7,32E-03 0,02041387 ! postreplication repair GO:0006301 25 9 0,000 7,32E-03 0,02039059 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 7,32E-03 0,02036737 ! icosanoid secretion GO:0032309 15 9 0,000 7,32E-03 0,0203442 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 7,32E-03 0,02032108 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 7,32E-03 0,02029801 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 7,32E-03 0,020275 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 7,32E-03 0,02025204 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 7,32E-03 0,02022913 ! sterol catabolic process GO:0016127 14 9 0,000 7,32E-03 0,02020627 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 7,32E-03 0,02018346 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 7,32E-03 0,02016071 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 7,32E-03 0,02013801 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 7,32E-03 0,02011535 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 7,32E-03 0,02009275 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 7,32E-03 0,0200702 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 7,32E-03 0,0200477 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 7,32E-03 0,02002525 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 7,32E-03 0,02000285 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 7,32E-03 0,0199805 ! regulation of synaptogenesis GO:0051963 15 9 0,000 7,32E-03 0,0199582 ! purine base metabolic process GO:0006144 25 9 0,000 7,32E-03 0,01993595 ! pigment granule transport GO:0051904 17 9 0,000 7,32E-03 0,01991375 ! regulation of telomere maintenance GO:0032204 17 9 0,000 7,32E-03 0,0198916 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 7,32E-03 0,0198695 ! regulation of muscle adaptation GO:0043502 14 9 0,000 7,32E-03 0,01984745 ! regulation of amino acid transport GO:0051955 12 9 0,000 7,32E-03 0,01982544 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 7,32E-03 0,01980349 ! mitochondrion localization GO:0051646 18 9 0,000 7,32E-03 0,01978158 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 8,13E-03 0,02194661 ! regulation of developmental growth GO:0048638 16 10 0,000 8,13E-03 0,02192238 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 0,000 8,13E-03 0,02189821 ! autophagic vacuole formation GO:0000045 17 10 0,000 8,13E-03 0,0218741 ! negative regulation of blood pressure GO:0045776 26 10 0,000 8,13E-03 0,02185003 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 8,13E-03 0,02182602 ! associative learning GO:0008306 21 10 0,000 8,13E-03 0,02180206 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 8,13E-03 0,02177816 ! regulation of phosphatase activity GO:0010921 28 10 0,000 8,13E-03 0,0217543 ! phosphate transport GO:0006817 24 10 0,000 8,13E-03 0,0217305 ! cell volume homeostasis GO:0006884 17 10 0,000 8,13E-03 0,02170675 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 8,13E-03 0,02168306 ! CTP metabolic process GO:0046036 11 10 0,000 8,13E-03 0,02165941 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 8,13E-03 0,02163582 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 8,13E-03 0,02161227 ! GTP metabolic process GO:0046039 11 10 0,000 8,13E-03 0,02158878 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 8,13E-03 0,02156534 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 8,13E-03 0,02154195 ! social behavior GO:0035176 29 10 0,000 8,13E-03 0,02151861 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 8,13E-03 0,02149532 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 8,13E-03 0,02147209 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 8,13E-03 0,0214489 ! androgen metabolic process GO:0008209 17 10 0,000 8,13E-03 0,02142576 ! phospholipid efflux GO:0033700 19 10 0,000 8,13E-03 0,02140267 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 8,13E-03 0,02137963 ! bile acid and bile salt transport GO:0015721 15 10 0,000 8,13E-03 0,02135665 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 8,13E-03 0,02133371 ! positive regulation of heart contraction GO:0045823 17 10 0,000 8,13E-03 0,02131082 ! lung alveolus development GO:0048286 26 10 0,000 8,13E-03 0,02128797 ! pathogenesis GO:0009405 17 10 0,000 8,13E-03 0,02126518 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 8,13E-03 0,02124244 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 8,13E-03 0,02121974 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 8,13E-03 0,0211971 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 8,13E-03 0,0211745 ! endoderm development GO:0007492 18 10 0,000 8,13E-03 0,02115195 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 8,13E-03 0,02112945 ! arginine catabolic process GO:0006527 17 10 0,000 8,13E-03 0,02110699 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 8,13E-03 0,02108459 ! proline metabolic process GO:0006560 13 10 0,000 8,13E-03 0,02106223 ! glucan biosynthetic process GO:0009250 14 10 0,000 8,13E-03 0,02103992 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 8,13E-03 0,02101765 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 8,13E-03 0,02099543 ! V(D)J recombination GO:0033151 34 10 0,000 8,13E-03 0,02097326 ! reverse cholesterol transport GO:0043691 19 10 0,000 8,13E-03 0,02095114 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 8,13E-03 0,02092906 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 8,13E-03 0,02090703 ! B cell proliferation GO:0042100 19 10 0,000 8,13E-03 0,02088505 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 8,13E-03 0,02086311 ! regulation of sodium ion transport GO:0002028 26 10 0,000 8,13E-03 0,02084122 ! multicellular organism growth GO:0035264 19 10 0,000 8,13E-03 0,02081937 ! phagocytosis, engulfment GO:0006911 33 10 0,000 8,13E-03 0,02079757 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 8,13E-03 0,02077582 ! ruffle organization GO:0031529 17 10 0,000 8,13E-03 0,02075411 ! epithelial cell development GO:0002064 21 10 0,000 8,13E-03 0,02073244 ! lens development in camera-type eye GO:0002088 17 10 0,000 8,13E-03 0,02071082 ! retinoic acid metabolic process GO:0042573 14 10 0,000 8,13E-03 0,02068925 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 8,13E-03 0,02066772 ! positive regulation of translational initiation GO:0045948 12 10 0,000 8,13E-03 0,02064624 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 8,13E-03 0,0206248 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 8,13E-03 0,0206034 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 8,13E-03 0,02058205 ! motor axon guidance GO:0008045 22 10 0,000 8,13E-03 0,02056075 ! copper ion homeostasis GO:0055070 13 10 0,000 8,13E-03 0,02053948 ! regulation of bone resorption GO:0045124 25 10 0,000 8,13E-03 0,02051826 ! protein heterooligomerization GO:0051291 17 10 0,000 8,13E-03 0,02049709 ! regulation of gliogenesis GO:0014013 23 10 0,000 8,13E-03 0,02047596 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 8,13E-03 0,02045487 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 8,13E-03 0,02043383 ! segment specification GO:0007379 15 10 0,000 8,13E-03 0,02041283 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 8,13E-03 0,02039187 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 8,13E-03 0,02037095 ! blastoderm segmentation GO:0007350 19 10 0,000 8,13E-03 0,02035008 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 8,13E-03 0,02032925 ! DNA ligation GO:0006266 18 10 0,000 8,13E-03 0,02030847 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 8,13E-03 0,02028772 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 8,13E-03 0,02026702 ! melanosome localization GO:0032400 16 10 0,000 8,13E-03 0,02024636 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 8,13E-03 0,02022574 ! regulation of B cell differentiation GO:0045577 24 10 0,000 8,13E-03 0,02020517 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 8,13E-03 0,02018463 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 8,13E-03 0,02016414 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 8,13E-03 0,02014369 ! induction of an organ GO:0001759 17 10 0,000 8,13E-03 0,02012328 ! leukocyte activation during immune response GO:0002366 15 10 0,000 8,13E-03 0,02010291 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 8,13E-03 0,02008259 ! protein sumoylation GO:0016925 17 10 0,000 8,13E-03 0,0200623 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 8,13E-03 0,02004206 ! hindbrain morphogenesis GO:0021575 19 10 0,000 8,13E-03 0,02002185 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 8,13E-03 0,02000169 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 8,13E-03 0,01998157 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 8,13E-03 0,01996149 ! salivary gland development GO:0007431 28 10 0,000 8,13E-03 0,01994145 ! ubiquinone metabolic process GO:0006743 17 10 0,000 8,13E-03 0,01992144 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 8,13E-03 0,01990148 ! midbrain development GO:0030901 14 10 0,000 8,13E-03 0,01988156 ! musculoskeletal movement GO:0050881 16 10 0,000 8,13E-03 0,01986168 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 8,13E-03 0,01984184 ! methionine biosynthetic process GO:0009086 21 10 0,000 8,13E-03 0,01982204 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 8,13E-03 0,01980227 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 8,13E-03 0,01978255 ! quaternary ammonium group transport GO:0015697 22 10 0,000 8,13E-03 0,01976287 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 8,13E-03 0,01974322 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 8,13E-03 0,01972361 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 8,13E-03 0,01970405 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 8,13E-03 0,01968452 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 8,13E-03 0,01966503 ! establishment of pigment granule localization GO:0051905 18 10 0,000 8,13E-03 0,01964558 ! blastocyst formation GO:0001825 18 10 0,000 8,13E-03 0,01962617 ! regulation of fibrinolysis GO:0051917 20 10 0,000 8,13E-03 0,01960679 ! cerebellar cortex development GO:0021695 16 10 0,000 8,13E-03 0,01958746 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 8,13E-03 0,01956816 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 8,13E-03 0,0195489 ! response to nicotine GO:0035094 20 10 0,000 8,13E-03 0,01952968 ! negative regulation of immune effector process GO:0002698 23 10 0,000 8,13E-03 0,01951049 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 8,13E-03 0,01949134 ! negative regulation of muscle development GO:0048635 27 11 0,000 8,94E-03 0,02141103 ! respiratory burst GO:0045730 17 11 0,000 8,94E-03 0,02139006 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 8,94E-03 0,02136913 ! neuron fate specification GO:0048665 18 11 0,000 8,94E-03 0,02134824 ! telencephalon cell migration GO:0022029 23 11 0,000 8,94E-03 0,02132739 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 8,94E-03 0,02130659 ! thyroid gland development GO:0030878 26 11 0,000 8,94E-03 0,02128582 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 8,94E-03 0,02126509 ! synapsis GO:0007129 14 11 0,000 8,94E-03 0,02124441 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 8,94E-03 0,02122376 ! Golgi vesicle budding GO:0048194 26 11 0,000 8,94E-03 0,02120316 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 8,94E-03 0,02118259 ! response to pain GO:0048265 27 11 0,000 8,94E-03 0,02116207 ! detection of mechanical stimulus GO:0050982 22 11 0,000 8,94E-03 0,02114158 ! keratinocyte proliferation GO:0043616 19 11 0,000 8,94E-03 0,02112113 ! blood vessel remodeling GO:0001974 30 11 0,000 8,94E-03 0,02110073 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 8,94E-03 0,02108036 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 8,94E-03 0,02106003 ! bone resorption GO:0045453 16 11 0,000 8,94E-03 0,02103974 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 8,94E-03 0,02101949 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 8,94E-03 0,02099928 ! negative regulation of proteolysis GO:0045861 25 11 0,000 8,94E-03 0,02097911 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 8,94E-03 0,02095897 ! melanocyte differentiation GO:0030318 20 11 0,000 8,94E-03 0,02093888 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 8,94E-03 0,02091882 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 8,94E-03 0,0208988 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 8,94E-03 0,02087883 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 8,94E-03 0,02085888 ! regulation of intracellular pH GO:0051453 21 11 0,000 8,94E-03 0,02083898 ! substrate-bound cell migration GO:0006929 14 11 0,000 8,94E-03 0,02081911 ! UV protection GO:0009650 20 11 0,000 8,94E-03 0,02079929 ! adult heart development GO:0007512 16 11 0,000 8,94E-03 0,0207795 ! chondrocyte differentiation GO:0002062 27 11 0,000 8,94E-03 0,02075974 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 8,94E-03 0,02074003 ! macroautophagy GO:0016236 19 11 0,000 8,94E-03 0,02072035 ! temperature homeostasis GO:0001659 18 11 0,000 8,94E-03 0,02070071 ! behavioral fear response GO:0001662 27 11 0,000 8,94E-03 0,02068111 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 8,94E-03 0,02066154 ! negative regulation of ossification GO:0030279 27 11 0,000 8,94E-03 0,02064201 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 8,94E-03 0,02062252 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 8,94E-03 0,02060307 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 8,94E-03 0,02058365 ! alpha-beta T cell activation GO:0046631 26 11 0,000 8,94E-03 0,02056427 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 8,94E-03 0,02054492 ! regulation of organ growth GO:0046620 14 11 0,000 8,94E-03 0,02052561 ! pigment granule localization GO:0051875 20 11 0,000 8,94E-03 0,02050634 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 8,94E-03 0,0204871 ! vasoconstriction GO:0042310 20 11 0,000 8,94E-03 0,0204679 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 8,94E-03 0,02044874 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 8,94E-03 0,02042961 ! embryonic axis specification GO:0000578 19 11 0,000 8,94E-03 0,02041052 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 8,94E-03 0,02039146 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 8,94E-03 0,02037244 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 8,94E-03 0,02035345 ! nitric oxide metabolic process GO:0046209 17 11 0,000 8,94E-03 0,0203345 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 8,94E-03 0,02031558 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 8,94E-03 0,0202967 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 8,94E-03 0,02027786 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 8,94E-03 0,02025905 ! prophase GO:0051324 17 11 0,000 8,94E-03 0,02024027 ! neuroblast proliferation GO:0007405 25 11 0,000 8,94E-03 0,02022153 ! nucleosome positioning GO:0016584 15 11 0,000 8,94E-03 0,02020282 ! regulation of isotype switching GO:0045191 24 11 0,000 8,94E-03 0,02018415 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 8,94E-03 0,02016551 ! negative regulation of neurological system process GO:0031645 21 11 0,000 8,94E-03 0,02014691 ! apical protein localization GO:0045176 18 11 0,000 8,94E-03 0,02012834 ! acid secretion GO:0046717 20 11 0,000 8,94E-03 0,02010981 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 8,94E-03 0,02009131 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 8,94E-03 0,02007284 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 8,94E-03 0,02005441 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 8,94E-03 0,02003601 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 8,94E-03 0,02001765 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 8,94E-03 0,01999931 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 8,94E-03 0,01998102 ! cholesterol efflux GO:0033344 21 11 0,000 8,94E-03 0,01996275 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 8,94E-03 0,01994452 ! oocyte development GO:0048599 20 11 0,000 8,94E-03 0,01992632 ! negative regulation of glucose import GO:0046325 18 11 0,000 8,94E-03 0,01990816 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 8,94E-03 0,01989003 ! embryonic gut development GO:0048566 19 11 0,000 8,94E-03 0,01987193 ! regulation of organic acid transport GO:0032890 19 11 0,000 8,94E-03 0,01985386 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 8,94E-03 0,01983583 ! activation of innate immune response GO:0002218 16 11 0,000 8,94E-03 0,01981783 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 8,94E-03 0,01979986 ! cardiac cell differentiation GO:0035051 36 11 0,000 8,94E-03 0,01978193 ! lysogeny GO:0030069 22 11 0,000 8,94E-03 0,01976403 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 8,94E-03 0,01974616 ! sequestering of metal ion GO:0051238 15 11 0,000 8,94E-03 0,01972832 ! regulation of embryonic development GO:0045995 35 11 0,000 8,94E-03 0,01971052 ! nucleus localization GO:0051647 22 11 0,000 8,94E-03 0,01969274 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 9,748E-03 0,02145519 ! positive regulation of blood pressure GO:0045777 18 12 0,000 9,748E-03 0,02143588 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 9,748E-03 0,0214166 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 9,748E-03 0,02139736 ! virus-host interaction GO:0019048 30 12 0,000 9,748E-03 0,02137815 ! regulation of B cell proliferation GO:0030888 22 12 0,000 9,748E-03 0,02135898 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 9,748E-03 0,02133984 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 9,748E-03 0,02132074 ! protein complex disassembly GO:0043241 28 12 0,000 9,748E-03 0,02130167 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 9,748E-03 0,02128263 ! regulation of cell projection assembly GO:0060491 33 12 0,000 9,748E-03 0,02126363 ! hippocampus development GO:0021766 29 12 0,000 9,748E-03 0,02124466 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 9,748E-03 0,02122573 ! cytokine biosynthetic process GO:0042089 23 12 0,000 9,748E-03 0,02120682 ! T cell proliferation GO:0042098 32 12 0,000 9,748E-03 0,02118796 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 9,748E-03 0,02116912 ! regulation of exit from mitosis GO:0007096 19 12 0,000 9,748E-03 0,02115032 ! ventral spinal cord development GO:0021517 25 12 0,000 9,748E-03 0,02113156 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 9,748E-03 0,02111282 ! drug transport GO:0015893 16 12 0,000 9,748E-03 0,02109412 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 9,748E-03 0,02107545 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 9,748E-03 0,02105682 ! tyrosine metabolic process GO:0006570 19 12 0,000 9,748E-03 0,02103822 ! polyamine metabolic process GO:0006595 18 12 0,000 9,748E-03 0,02101965 ! focal adhesion formation GO:0048041 37 12 0,000 9,748E-03 0,02100111 ! mitotic spindle organization GO:0007052 23 12 0,000 9,748E-03 0,02098261 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 9,748E-03 0,02096414 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 9,748E-03 0,0209457 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 9,748E-03 0,0209273 ! lipid digestion GO:0044241 21 12 0,000 9,748E-03 0,02090892 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 9,748E-03 0,02089058 ! entry into host cell GO:0030260 34 12 0,000 9,748E-03 0,02087227 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 9,748E-03 0,020854 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 9,748E-03 0,02083575 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 9,748E-03 0,02081754 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 9,748E-03 0,02079936 ! protein targeting to peroxisome GO:0006625 27 12 0,000 9,748E-03 0,02078121 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 9,748E-03 0,02076309 ! regulation of phagocytosis GO:0050764 17 12 0,000 9,748E-03 0,020745 ! snRNA metabolic process GO:0016073 30 12 0,000 9,748E-03 0,02072695 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 9,748E-03 0,02070893 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 9,748E-03 0,02069093 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 9,748E-03 0,02067297 ! cranial nerve development GO:0021545 23 12 0,000 9,748E-03 0,02065504 ! fucose catabolic process GO:0019317 25 12 0,000 9,748E-03 0,02063714 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 9,748E-03 0,02061928 ! histone acetylation GO:0016573 27 12 0,000 9,748E-03 0,02060144 ! mRNA polyadenylation GO:0006378 24 12 0,000 9,748E-03 0,02058363 ! autonomic nervous system development GO:0048483 24 12 0,000 9,748E-03 0,02056586 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 9,748E-03 0,02054811 ! zymogen activation GO:0031638 18 12 0,000 9,748E-03 0,0205304 ! peptidyl-lysine modification GO:0018205 21 12 0,000 9,748E-03 0,02051272 ! T cell homeostasis GO:0043029 28 12 0,000 9,748E-03 0,02049506 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 9,748E-03 0,02047744 ! glutathione biosynthetic process GO:0006750 15 12 0,000 9,748E-03 0,02045985 ! regulation of leukocyte migration GO:0002685 29 12 0,000 9,748E-03 0,02044229 ! oocyte differentiation GO:0009994 21 12 0,000 9,748E-03 0,02042475 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 9,748E-03 0,02040725 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 9,748E-03 0,02038978 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 9,748E-03 0,02037234 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 9,748E-03 0,02035493 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 9,748E-03 0,02033754 ! defense response to fungus GO:0050832 15 12 0,000 9,748E-03 0,02032019 ! developmental induction GO:0031128 22 12 0,000 9,748E-03 0,02030287 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 9,748E-03 0,02028557 ! lamellipodium assembly GO:0030032 24 12 0,000 9,748E-03 0,02026831 ! response to cold GO:0009409 17 12 0,000 9,748E-03 0,02025107 ! establishment of cell polarity GO:0030010 21 12 0,000 9,748E-03 0,02023387 ! regulation of synapse organization GO:0050807 18 12 0,000 9,748E-03 0,02021669 ! localization within membrane GO:0051668 26 12 0,000 9,748E-03 0,02019955 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,01055658 0,02185569 ! cGMP metabolic process GO:0046068 18 13 0,000 0,01055658 0,02183719 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,01055658 0,02181871 ! regulation of chemokine production GO:0032642 18 13 0,000 0,01055658 0,02180027 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,01055658 0,02178186 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,01055658 0,02176348 ! peroxisomal transport GO:0043574 28 13 0,000 0,01055658 0,02174513 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,01055658 0,02172681 ! cartilage condensation GO:0001502 22 13 0,000 0,01055658 0,02170852 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,01055658 0,02169026 ! organelle fusion GO:0048284 36 13 0,000 0,01055658 0,02167203 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,01055658 0,02165384 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,01055658 0,02163567 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,01055658 0,02161754 ! endocrine pancreas development GO:0031018 25 13 0,000 0,01055658 0,02159943 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,01055658 0,02158136 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,01055658 0,02156331 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,01055658 0,0215453 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,01055658 0,02152731 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,01055658 0,02150936 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,01055658 0,02149143 ! methionine metabolic process GO:0006555 31 13 0,000 0,01055658 0,02147354 ! plasma membrane organization GO:0007009 27 13 0,000 0,01055658 0,02145567 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,01055658 0,02143784 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,01055658 0,02142003 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,01055658 0,02140226 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,01055658 0,02138451 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,01055658 0,02136679 ! cytokine metabolic process GO:0042107 24 13 0,000 0,01055658 0,02134911 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,01055658 0,02133145 ! exocrine system development GO:0035272 34 13 0,000 0,01055658 0,02131382 ! asymmetric protein localization GO:0008105 24 13 0,000 0,01055658 0,02129622 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,01055658 0,02127865 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,01055658 0,0212611 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,01055658 0,02124359 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,01055658 0,02122611 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,01055658 0,02120865 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,01055658 0,02119122 ! protein homotetramerization GO:0051289 24 13 0,000 0,01055658 0,02117383 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,01055658 0,02115646 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,01055658 0,02113911 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,01055658 0,0211218 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,01055658 0,02110452 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,01055658 0,02108726 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01055658 0,02107003 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 0,01055658 0,02105283 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,01055658 0,02103566 ! histone methylation GO:0016571 29 13 0,000 0,01055658 0,02101852 ! chromatin silencing GO:0006342 29 13 0,000 0,01055658 0,0210014 ! gland morphogenesis GO:0022612 31 13 0,000 0,01055658 0,02098431 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,01055658 0,02096725 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,01055658 0,02095022 ! regulation of epidermis development GO:0045682 19 13 0,000 0,01055658 0,02093321 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,01055658 0,02091624 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,01055658 0,02089929 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,01055658 0,02088236 ! spleen development GO:0048536 24 13 0,000 0,01055658 0,02086547 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,01055658 0,0208486 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,01055658 0,02083176 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,01055658 0,02081495 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,01055658 0,02079816 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,01055658 0,0207814 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,01055658 0,02076467 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,01055658 0,02074796 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,01055658 0,02073129 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,01055658 0,02071463 ! insulin secretion GO:0030073 24 13 0,000 0,01055658 0,02069801 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,01055658 0,02068141 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,01055658 0,02066484 ! acrosome reaction GO:0007340 19 13 0,000 0,01055658 0,02064829 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,01055658 0,02063178 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,01055658 0,02061528 ! rRNA transcription GO:0009303 28 14 0,000 0,01136415 0,02217462 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,01136415 0,02215692 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,01136415 0,02213925 ! water transport GO:0006833 21 14 0,000 0,01136415 0,02212161 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,01136415 0,022104 ! non-recombinational repair GO:0000726 29 14 0,000 0,01136415 0,02208641 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,01136415 0,02206885 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,01136415 0,02205133 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,01136415 0,02203382 ! RNA polyadenylation GO:0043631 32 14 0,000 0,01136415 0,02201635 ! lipid localization GO:0010876 32 14 0,000 0,01136415 0,02199891 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,01136415 0,02198149 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,01136415 0,0219641 ! regulated secretory pathway GO:0045055 24 14 0,000 0,01136415 0,02194673 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,01136415 0,0219294 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,01136415 0,02191209 ! arginine metabolic process GO:0006525 21 14 0,000 0,01136415 0,02189481 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,01136415 0,02187756 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,01136415 0,02186033 ! regulation of heart rate GO:0002027 25 14 0,000 0,01136415 0,02184313 ! fear response GO:0042596 34 14 0,000 0,01136415 0,02182596 ! organic alcohol transport GO:0015850 29 14 0,000 0,01136415 0,02180881 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,01136415 0,02179169 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,01136415 0,0217746 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,01136415 0,02175754 ! neutral amino acid transport GO:0015804 28 14 0,000 0,01136415 0,0217405 ! bone mineralization GO:0030282 18 14 0,000 0,01136415 0,02172349 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,01136415 0,0217065 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,01136415 0,02168955 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,01136415 0,02167261 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,01136415 0,02165571 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,01136415 0,02163883 ! regulation of cellular pH GO:0030641 27 14 0,000 0,01136415 0,02162198 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,01136415 0,02160515 ! ribosome assembly GO:0042255 18 14 0,000 0,01136415 0,02158835 ! cerebellum development GO:0021549 23 14 0,000 0,01136415 0,02157158 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,01136415 0,02155483 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,01136415 0,02153811 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,01136415 0,02152141 ! response to gamma radiation GO:0010332 30 14 0,000 0,01136415 0,02150474 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,01136415 0,0214881 ! NADP metabolic process GO:0006739 24 14 0,000 0,01136415 0,02147148 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,01136415 0,02145488 ! oxygen transport GO:0015671 22 14 0,000 0,01136415 0,02143832 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,01136415 0,02142177 ! male genitalia development GO:0030539 26 14 0,000 0,01136415 0,02140526 ! regulation of RNA stability GO:0043487 33 14 0,000 0,01136415 0,02138877 ! regulation of axon extension GO:0030516 43 14 0,000 0,01136415 0,0213723 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,01136415 0,02135586 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,01136415 0,02133945 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,01136415 0,02132306 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,01217109 0,02281962 ! lactation GO:0007595 30 15 0,000 0,01217109 0,02280212 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 0,01217109 0,02278465 ! reproductive cellular process GO:0048610 22 15 0,000 0,01217109 0,0227672 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,01217109 0,02274978 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,01217109 0,02273239 ! superoxide anion generation GO:0042554 22 15 0,000 0,01217109 0,02271502 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,01217109 0,02269768 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,01217109 0,02268037 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,01217109 0,02266308 ! copper ion transport GO:0006825 22 15 0,000 0,01217109 0,02264582 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,01217109 0,02262859 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,01217109 0,02261138 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,01217109 0,0225942 ! sulfate transport GO:0008272 27 15 0,000 0,01217109 0,02257704 ! response to cAMP GO:0051591 25 15 0,000 0,01217109 0,02255991 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,01217109 0,02254281 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,01217109 0,02252573 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,01217109 0,02250868 ! response to hexose stimulus GO:0009746 25 15 0,000 0,01217109 0,02249165 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,01217109 0,02247465 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,01217109 0,02245768 ! vesicle coating GO:0006901 38 15 0,000 0,01217109 0,02244073 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,01217109 0,0224238 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,01217109 0,02240691 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,01217109 0,02239003 ! regulation of exocytosis GO:0017157 26 15 0,000 0,01217109 0,02237319 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,01217109 0,02235636 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,01217109 0,02233957 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,01217109 0,0223228 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,01217109 0,02230605 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,01217109 0,02228933 ! regulation of vasodilation GO:0042312 27 15 0,000 0,01217109 0,02227263 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,01217109 0,02225596 ! histone deacetylation GO:0016575 24 15 0,000 0,01217109 0,02223931 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,01217109 0,02222269 ! water homeostasis GO:0030104 28 15 0,000 0,01217109 0,0222061 ! cofactor transport GO:0051181 30 15 0,000 0,01217109 0,02218953 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,01217109 0,02217298 ! muscle maintenance GO:0046716 26 15 0,000 0,01217109 0,02215646 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,01217109 0,02213996 ! intestinal absorption GO:0050892 31 15 0,000 0,01217109 0,02212349 ! dopamine metabolic process GO:0042417 35 15 0,000 0,01217109 0,02210704 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,01217109 0,02209061 ! heme biosynthetic process GO:0006783 33 15 0,000 0,01217109 0,02207421 ! cell killing GO:0001906 32 15 0,000 0,01217109 0,02205784 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,01217109 0,02204149 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,01217109 0,02202516 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,01217109 0,02200886 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,01217109 0,02199258 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,01217109 0,02197632 ! actin filament polymerization GO:0030041 27 15 0,000 0,01217109 0,02196009 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,01217109 0,02194388 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,01297739 0,02338035 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,01297739 0,02336312 ! positive regulation of cell size GO:0045793 29 16 0,000 0,01297739 0,02334592 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,01297739 0,02332874 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,01297739 0,02331158 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,01297739 0,02329446 ! bone remodeling GO:0046849 28 16 0,000 0,01297739 0,02327735 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,01297739 0,02326028 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,01297739 0,02324322 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,01297739 0,02322619 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,01297739 0,02320919 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,01297739 0,02319221 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,01297739 0,02317526 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,01297739 0,02315833 ! startle response GO:0001964 28 16 0,000 0,01297739 0,02314143 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,01297739 0,02312455 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,01297739 0,02310769 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,01297739 0,02309086 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,01297739 0,02307406 ! protein polyubiquitination GO:0000209 41 16 0,000 0,01297739 0,02305728 ! glutamate metabolic process GO:0006536 25 16 0,000 0,01297739 0,02304052 ! pituitary gland development GO:0021983 30 16 0,000 0,01297739 0,02302379 ! response to osmotic stress GO:0006970 27 16 0,000 0,01297739 0,02300708 ! lysosomal transport GO:0007041 31 16 0,000 0,01297739 0,0229904 ! fructose metabolic process GO:0006000 25 16 0,000 0,01297739 0,02297374 ! L-amino acid transport GO:0015807 33 16 0,000 0,01297739 0,0229571 ! stem cell development GO:0048864 46 16 0,000 0,01297739 0,02294049 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,01297739 0,0229239 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,01297739 0,02290734 ! intermediate filament-based process GO:0045103 36 16 0,000 0,01297739 0,0228908 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,01297739 0,02287428 ! negative regulation of immune response GO:0050777 38 16 0,000 0,01297739 0,02285779 ! axon cargo transport GO:0008088 46 16 0,000 0,01297739 0,02284132 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,01297739 0,02282488 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,01297739 0,02280846 ! DNA replication initiation GO:0006270 28 16 0,000 0,01297739 0,02279206 ! neuron recognition GO:0008038 40 16 0,000 0,01297739 0,02277569 ! mRNA splice site selection GO:0006376 44 16 0,000 0,01297739 0,02275934 ! tissue regeneration GO:0042246 27 16 0,000 0,01297739 0,02274301 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,01297739 0,02272671 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,01297739 0,02271043 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,01297739 0,02269417 ! biomineral formation GO:0031214 22 16 0,000 0,01297739 0,02267794 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,01297739 0,02266173 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,01297739 0,02264554 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,01297739 0,02262938 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,01297739 0,02261323 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,01297739 0,02259712 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,01297739 0,02258102 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,01297739 0,02256495 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,01297739 0,0225489 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,01297739 0,02253288 ! peptide hormone processing GO:0016486 27 16 0,000 0,01297739 0,02251687 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,01378305 0,0238978 ! metencephalon development GO:0022037 32 17 0,000 0,01378305 0,02388085 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,01378305 0,02386392 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,01378305 0,02384702 ! signal complex assembly GO:0007172 47 17 0,000 0,01378305 0,02383014 ! filopodium assembly GO:0046847 42 17 0,000 0,01378305 0,02381329 ! endothelial cell migration GO:0043542 31 17 0,000 0,01378305 0,02379646 ! gene silencing by RNA GO:0031047 38 17 0,000 0,01378305 0,02377966 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,01378305 0,02376288 ! glial cell development GO:0021782 28 17 0,000 0,01378305 0,02374612 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,01378305 0,02372938 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,01378305 0,02371267 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,01378305 0,02369598 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,01378305 0,02367932 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,01378305 0,02366268 ! myoblast differentiation GO:0045445 50 17 0,000 0,01378305 0,02364606 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,01378305 0,02362947 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,01378305 0,0236129 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,01378305 0,02359635 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,01378305 0,02357983 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,01378305 0,02356333 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,01378305 0,02354685 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,01378305 0,02353039 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,01378305 0,02351396 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,01378305 0,02349755 ! membrane budding GO:0006900 42 17 0,000 0,01378305 0,02348117 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,01378305 0,0234648 ! regulation of protein binding GO:0043393 33 17 0,000 0,01378305 0,02344846 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,01378305 0,02343215 ! genitalia development GO:0048806 32 17 0,000 0,01378305 0,02341585 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,01378305 0,02339958 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,01378305 0,02338333 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,01378305 0,0233671 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,01378305 0,0233509 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,01378305 0,02333472 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,01378305 0,02331856 ! steroid catabolic process GO:0006706 34 17 0,000 0,01378305 0,02330242 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,01378305 0,0232863 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,01378305 0,02327021 ! gas transport GO:0015669 26 17 0,000 0,01378305 0,02325414 ! organic cation transport GO:0015695 32 17 0,000 0,01378305 0,02323809 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,01378305 0,02322206 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,01378305 0,02320606 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,01458808 0,02454455 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,01458808 0,02452765 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,01458808 0,02451079 ! limbic system development GO:0021761 40 18 0,000 0,01458808 0,02449394 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,01458808 0,02447712 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,01458808 0,02446032 ! adult walking behavior GO:0007628 36 18 0,000 0,01458808 0,02444354 ! patterning of blood vessels GO:0001569 43 18 0,000 0,01458808 0,02442679 ! heart looping GO:0001947 34 18 0,000 0,01458808 0,02441006 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,01458808 0,02439335 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,01458808 0,02437666 ! centrosome cycle GO:0007098 26 18 0,000 0,01458808 0,02436 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,01458808 0,02434336 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,01458808 0,02432675 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,01458808 0,02431015 ! glycine metabolic process GO:0006544 30 18 0,000 0,01458808 0,02429358 ! glutamine metabolic process GO:0006541 29 18 0,000 0,01458808 0,02427703 ! response to retinoic acid GO:0032526 31 18 0,000 0,01458808 0,02426051 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,01458808 0,024244 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 0,000 0,01458808 0,02422752 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,01458808 0,02421106 ! DNA integration GO:0015074 32 18 0,000 0,01458808 0,02419462 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,01458808 0,02417821 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,01458808 0,02416182 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,01458808 0,02414545 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,01458808 0,0241291 ! neural crest cell migration GO:0001755 41 18 0,000 0,01458808 0,02411278 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,01458808 0,02409647 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,01458808 0,02408019 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,01458808 0,02406393 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,01458808 0,02404769 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,01458808 0,02403148 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,01458808 0,02401528 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,01458808 0,02399911 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,01458808 0,02398296 ! detection of bacterium GO:0016045 22 18 0,000 0,01458808 0,02396683 ! nerve development GO:0021675 34 18 0,000 0,01458808 0,02395073 ! defense response to virus GO:0051607 43 18 0,000 0,01458808 0,02393464 ! microspike assembly GO:0030035 46 18 0,000 0,01458808 0,02391858 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,01458808 0,02390254 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,01458808 0,02388652 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,01539248 0,02518675 ! positive regulation of translation GO:0045727 31 19 0,000 0,01539248 0,02516989 ! negative regulation of defense response GO:0031348 27 19 0,000 0,01539248 0,02515306 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,01539248 0,02513624 ! neuron maturation GO:0042551 46 19 0,000 0,01539248 0,02511945 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,01539248 0,02510268 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,01539248 0,02508594 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,01539248 0,02506921 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,01539248 0,02505251 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,01539248 0,02503583 ! inositol metabolic process GO:0006020 33 19 0,000 0,01539248 0,02501917 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,01539248 0,02500254 ! memory GO:0007613 34 19 0,000 0,01539248 0,02498593 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,01539248 0,02496934 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,01539248 0,02495277 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,01539248 0,02493622 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,01539248 0,02491969 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,01539248 0,02490319 ! cerebral cortex development GO:0021987 40 19 0,000 0,01539248 0,02488671 ! pigmentation during development GO:0048066 42 19 0,000 0,01539248 0,02487025 ! response to vitamin A GO:0033189 32 19 0,000 0,01539248 0,02485381 ! heme metabolic process GO:0042168 40 19 0,000 0,01539248 0,0248374 ! neuromuscular junction development GO:0007528 43 19 0,000 0,01539248 0,024821 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,01539248 0,02480463 ! response to fungus GO:0009620 26 19 0,000 0,01539248 0,02478828 ! peptide cross-linking GO:0018149 39 19 0,000 0,01539248 0,02477195 ! protein export from nucleus GO:0006611 40 19 0,000 0,01539248 0,02475564 ! heart process GO:0003015 32 19 0,000 0,01539248 0,02473935 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,01539248 0,02472309 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,01539248 0,02470685 ! visual learning GO:0008542 38 19 0,000 0,01539248 0,02469062 ! cellular pigmentation GO:0033059 37 19 0,000 0,01539248 0,02467442 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,01539248 0,02465824 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,01539248 0,02464208 ! vitamin transport GO:0051180 31 19 0,000 0,01539248 0,02462595 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,01539248 0,02460983 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,01539248 0,02459373 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,01539248 0,02457766 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,01539248 0,02456161 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,01539248 0,02454557 ! cilium assembly GO:0042384 38 19 0,000 0,01539248 0,02452956 ! peptide hormone secretion GO:0030072 32 19 0,000 0,01539248 0,02451357 ! protein secretion GO:0009306 45 20 0,000 0,01619624 0,02577681 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,01619624 0,02576003 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,01619624 0,02574327 ! positive regulation of ossification GO:0045778 50 20 0,000 0,01619624 0,02572653 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,01619624 0,02570982 ! skin development GO:0043588 42 20 0,000 0,01619624 0,02569312 ! phosphoinositide phosphorylation GO:0046854 40 20 0,000 0,01619624 0,02567645 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,01619624 0,0256598 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,01619624 0,02564317 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,01619624 0,02562656 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 0,000 0,01619624 0,02560997 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,01619624 0,02559341 ! response to vitamin GO:0033273 36 20 0,000 0,01619624 0,02557686 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,01619624 0,02556034 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,01619624 0,02554384 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,01619624 0,02552736 ! bile acid metabolic process GO:0008206 34 20 0,000 0,01619624 0,0255109 ! response to alkaloid GO:0043279 38 20 0,000 0,01619624 0,02549446 ! retinoid metabolic process GO:0001523 34 20 0,000 0,01619624 0,02547805 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,01619624 0,02546165 ! apoptotic mitochondrial changes GO:0008637 42 20 0,000 0,01619624 0,02544528 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,01619624 0,02542893 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,01619624 0,02541259 GO:0032392|DNA geometric change, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,01619624 0,02539628 ! actin filament bundle formation GO:0051017 47 20 0,000 0,01619624 0,02537999 ! body fluid secretion GO:0007589 33 20 0,000 0,01619624 0,02536372 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,01619624 0,02534747 ! peptide secretion GO:0002790 38 20 0,000 0,01619624 0,02533125 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,01619624 0,02531504 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,01619624 0,02529885 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,01619624 0,02528269 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,01619624 0,02526654 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,01619624 0,02525042 ! cell-cell junction organization GO:0045216 43 20 0,000 0,01619624 0,02523432 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,01619624 0,02521823 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,01619624 0,02520217 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,01619624 0,02518613 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,01619624 0,02517011 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,01619624 0,02515411 ! regulation of glucose import GO:0046324 30 20 0,000 0,01619624 0,02513812 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,01619624 0,02512216 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,01619624 0,02510622 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,01619624 0,0250903 ! negative regulation of translation GO:0017148 32 20 0,000 0,01619624 0,0250744 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,01619624 0,02505852 ! regulation of cell killing GO:0031341 46 21 0,000 0,01699937 0,02628446 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,01699937 0,02626784 ! hormone secretion GO:0046879 39 21 0,000 0,01699937 0,02625123 ! lipid phosphorylation GO:0046834 43 21 0,000 0,01699937 0,02623465 ! cAMP metabolic process GO:0046058 41 21 0,000 0,01699937 0,02621809 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,01699937 0,02620155 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,01699937 0,02618502 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,01699937 0,02616853 ! ovarian follicle development GO:0001541 39 21 0,000 0,01699937 0,02615205 ! smooth muscle contraction GO:0006939 48 21 0,000 0,01699937 0,02613559 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 0,000 0,01699937 0,02611915 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,01699937 0,02610273 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,01699937 0,02608634 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,01699937 0,02606996 ! plasma membrane fusion GO:0045026 33 21 0,000 0,01699937 0,02605361 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,01699937 0,02603727 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,01699937 0,02602096 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,01699937 0,02600466 ! sensory perception of pain GO:0019233 33 21 0,000 0,01699937 0,02598839 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,01699937 0,02597214 ! diencephalon development GO:0021536 36 21 0,000 0,01699937 0,02595591 ! collagen fibril organization GO:0030199 62 21 0,000 0,01699937 0,02593969 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,01699937 0,0259235 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,01699937 0,02590733 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,01699937 0,02589118 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,01699937 0,02587505 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,01699937 0,02585893 ! collagen catabolic process GO:0030574 29 21 0,000 0,01699937 0,02584284 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,01699937 0,02582677 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,01699937 0,02581072 ! sperm-egg recognition GO:0035036 23 21 0,000 0,01699937 0,02579469 ! actin filament-based movement GO:0030048 47 21 0,000 0,01699937 0,02577868 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,01699937 0,02576269 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,01780186 0,02696215 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,01780186 0,02694544 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,01780186 0,02692876 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,01780186 0,02691209 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,01780186 0,02689545 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,01780186 0,02687883 ! microtubule-based transport GO:0010970 59 22 0,000 0,01780186 0,02686223 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,01780186 0,02684564 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,01780186 0,02682908 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,01780186 0,02681254 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,01780186 0,02679602 ! cellular response to starvation GO:0009267 37 22 0,000 0,01780186 0,02677952 ! vacuolar transport GO:0007034 41 22 0,000 0,01780186 0,02676304 ! central nervous system neuron development GO:0021954 47 22 0,000 0,01780186 0,02674658 ! fucose metabolic process GO:0006004 44 22 0,000 0,01780186 0,02673014 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,01780186 0,02671372 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,01780186 0,02669733 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,01780186 0,02668095 ! ureteric bud development GO:0001657 50 22 0,000 0,01780186 0,02666459 ! cell aging GO:0007569 48 22 0,000 0,01780186 0,02664825 ! stem cell differentiation GO:0048863 57 22 0,000 0,01780186 0,02663193 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,01780186 0,02661563 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,01780186 0,02659935 ! cytolysis GO:0019835 27 22 0,000 0,01780186 0,0265831 ! renal system process GO:0003014 42 22 0,000 0,01780186 0,02656686 ! vasodilation GO:0042311 40 22 0,000 0,01780186 0,02655064 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,01780186 0,02653444 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,01780186 0,02651826 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 0,01780186 0,0265021 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,01780186 0,02648596 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,01780186 0,02646984 ! positive regulation of intracellular transport GO:0032388 42 22 0,000 0,01780186 0,02645374 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,01780186 0,02643766 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,01780186 0,02642159 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,01780186 0,02640555 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,01780186 0,02638953 ! sarcomere organization GO:0045214 32 22 0,000 0,01780186 0,02637353 ! positive regulation of B cell activation GO:0050871 42 22 0,000 0,01780186 0,02635754 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,01780186 0,02634158 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,01780186 0,02632563 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,01780186 0,02630971 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,01780186 0,0262938 ! gut development GO:0048565 44 22 0,000 0,01780186 0,02627791 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,01780186 0,02626204 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,01780186 0,02624619 ! protein stabilization GO:0050821 41 22 0,000 0,01780186 0,02623036 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,01860372 0,02739535 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,01860372 0,02737885 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,01860372 0,02736237 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,01860372 0,0273459 ! gluconeogenesis GO:0006094 38 23 0,000 0,01860372 0,02732946 ! glycerol metabolic process GO:0006071 40 23 0,000 0,01860372 0,02731304 ! viral genome replication GO:0019079 44 23 0,000 0,01860372 0,02729663 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,01860372 0,02728025 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,01860372 0,02726388 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,01860372 0,02724754 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,01860372 0,02723121 ! regeneration GO:0031099 42 23 0,000 0,01860372 0,02721491 ! axis specification GO:0009798 43 23 0,000 0,01860372 0,02719862 ! visual behavior GO:0007632 46 23 0,000 0,01860372 0,02718235 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,01860372 0,0271661 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 0,01860372 0,02714988 ! response to ethanol GO:0045471 47 23 0,000 0,01860372 0,02713367 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,01860372 0,02711748 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,01860372 0,02710131 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,01860372 0,02708516 ! peroxisome organization GO:0007031 43 23 0,000 0,01860372 0,02706902 ! lysosome organization GO:0007040 47 23 0,000 0,01860372 0,02705291 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,01860372 0,02703682 ! vesicle targeting GO:0006903 49 23 0,000 0,01860372 0,02702074 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,01860372 0,02700469 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,01860372 0,02698865 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,01860372 0,02697264 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,01860372 0,02695664 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,01860372 0,02694066 ! DNA modification GO:0006304 36 23 0,000 0,01860372 0,0269247 ! fatty acid transport GO:0015908 47 23 0,000 0,01860372 0,02690876 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,01860372 0,02689284 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,01860372 0,02687693 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,01860372 0,02686105 ! hormone transport GO:0009914 41 23 0,000 0,01860372 0,02684518 ! cell-cell recognition GO:0009988 28 23 0,000 0,01860372 0,02682933 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,01860372 0,02681351 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,01860372 0,0267977 GO:0006099|tricarboxylic acid cycle, ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,01940495 0,02793536 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,01940495 0,0279189 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,01940495 0,02790247 ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,01940495 0,02788606 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,01940495 0,02786966 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,01940495 0,02785329 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,01940495 0,02783693 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,01940495 0,0278206 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,01940495 0,02780428 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,01940495 0,02778798 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,01940495 0,0277717 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 0,000 0,01940495 0,02775544 ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,01940495 0,0277392 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,01940495 0,02772298 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,01940495 0,02770678 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,01940495 0,02769059 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,01940495 0,02767443 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,01940495 0,02765828 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,01940495 0,02764216 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,01940495 0,02762605 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 52 24 0,000 0,01940495 0,02760996 ! leukotriene metabolic process GO:0006691 47 24 0,000 0,01940495 0,02759389 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,01940495 0,02757783 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,01940495 0,0275618 ! membrane depolarization GO:0051899 45 24 0,000 0,01940495 0,02754579 ! pallium development GO:0021543 56 24 0,000 0,01940495 0,02752979 ! oogenesis GO:0048477 44 24 0,000 0,01940495 0,02751381 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,01940495 0,02749785 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,01940495 0,02748191 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 0,01940495 0,02746599 ! platelet activation GO:0030168 41 24 0,000 0,01940495 0,02745009 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,01940495 0,0274342 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,01940495 0,02741833 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,01940495 0,02740248 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,01940495 0,02738665 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,01940495 0,02737084 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,01940495 0,02735505 ! regulation of amine transport GO:0051952 41 24 0,000 0,01940495 0,02733927 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,01940495 0,02732351 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,02020555 0,02843442 ! positive regulation of fibroblast proliferation GO:0048146 48 25 0,000 0,02020555 0,02841805 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,02020555 0,0284017 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 0,000 0,02020555 0,02838537 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,02020555 0,02836906 ! leukocyte adhesion GO:0007159 55 25 0,000 0,02020555 0,02835276 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,02020555 0,02833649 ! phototransduction GO:0007602 37 25 0,000 0,02020555 0,02832023 ! keratinization GO:0031424 37 25 0,000 0,02020555 0,02830399 ! vasculogenesis GO:0001570 49 25 0,000 0,02020555 0,02828777 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,02020555 0,02827157 ! vacuole organization GO:0007033 49 25 0,000 0,02020555 0,02825539 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,02020555 0,02823922 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,02020555 0,02822308 ! receptor metabolic process GO:0043112 53 25 0,000 0,02020555 0,02820695 ! chromosome condensation GO:0030261 48 25 0,000 0,02020555 0,02819084 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,02020555 0,02817475 ! regulation of behavior GO:0050795 48 25 0,000 0,02020555 0,02815868 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,02020555 0,02814262 ! interaction with host GO:0051701 66 25 0,000 0,02020555 0,02812659 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,02020555 0,02811057 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,02020555 0,02809457 ! immunoglobulin production GO:0002377 62 25 0,000 0,02020555 0,02807859 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,02020555 0,02806263 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,02020555 0,02804668 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,02020555 0,02803076 ! liver development GO:0001889 55 25 0,000 0,02020555 0,02801485 ! protein tetramerization GO:0051262 57 25 0,000 0,02020555 0,02799896 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,02100552 0,02909098 ! myelination GO:0042552 50 26 0,000 0,02100552 0,02907449 ! initiation of viral infection GO:0019059 60 26 0,000 0,02100552 0,02905803 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,02100552 0,02904158 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,02100552 0,02902516 ! molting cycle process GO:0022404 52 26 0,000 0,02100552 0,02900875 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,02100552 0,02899236 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,02100552 0,02897599 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,02100552 0,02895964 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,02100552 0,02894331 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,02100552 0,02892699 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,02100552 0,02891069 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,02100552 0,02889441 ! digestive system process GO:0022600 49 26 0,000 0,02100552 0,02887815 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,02100552 0,02886191 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,02100552 0,02884569 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 0,000 0,02100552 0,02882948 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,02100552 0,0288133 ! osteoblast differentiation GO:0001649 63 26 0,000 0,02100552 0,02879713 ! neural crest cell development GO:0014032 59 26 0,000 0,02100552 0,02878098 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,02100552 0,02876484 ! negative regulation of cell development GO:0010721 83 26 0,000 0,02100552 0,02874873 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,02100552 0,02873263 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,02100552 0,02871655 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,02100552 0,02870049 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,02100552 0,02868445 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,02100552 0,02866842 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,02100552 0,02865242 ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,02100552 0,02863643 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,02100552 0,02862046 ! blastocyst development GO:0001824 50 26 0,000 0,02100552 0,0286045 ! telomere organization GO:0032200 46 26 0,000 0,02100552 0,02858857 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,02100552 0,02857265 ! neural tube closure GO:0001843 58 26 0,000 0,02100552 0,02855675 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,02100552 0,02854087 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,02100552 0,028525 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,02100552 0,02850916 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,02180485 0,0295776 ! embryonic pattern specification GO:0009880 49 27 0,000 0,02180485 0,02956119 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,02180485 0,02954479 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,02180485 0,02952841 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,02180485 0,02951206 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,02180485 0,02949571 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,02180485 0,02947939 ! iron ion transport GO:0006826 65 27 0,000 0,02180485 0,02946309 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,02180485 0,0294468 ! superoxide metabolic process GO:0006801 41 27 0,000 0,02180485 0,02943053 ! tube lumen formation GO:0035148 59 27 0,000 0,02180485 0,02941428 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,02180485 0,02939805 ! insulin receptor signaling pathway GO:0008286 66 27 0,000 0,02180485 0,02938183 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,02180485 0,02936563 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,02180485 0,02934945 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,02180485 0,02933329 ! response to starvation GO:0042594 47 27 0,000 0,02180485 0,02931715 ! response to toxin GO:0009636 49 27 0,000 0,02180485 0,02930102 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,02180485 0,02928491 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,02180485 0,02926882 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,02180485 0,02925275 ! leukocyte proliferation GO:0070661 59 27 0,000 0,02180485 0,0292367 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,02180485 0,02922066 ! regulation of fibroblast proliferation GO:0048145 56 28 0,000 0,02260356 0,0302744 ! neuron fate commitment GO:0048663 52 28 0,000 0,02260356 0,03025781 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 0,000 0,02260356 0,03024124 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,02260356 0,03022468 ! protein amino acid acylation GO:0043543 59 28 0,000 0,02260356 0,03020815 ! vesicle docking GO:0048278 55 28 0,000 0,02260356 0,03019163 ! circadian rhythm GO:0007623 56 28 0,000 0,02260356 0,03017514 ! dendrite development GO:0016358 67 28 0,000 0,02260356 0,03015866 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,02260356 0,03014219 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,02260356 0,03012575 ! sperm motility GO:0030317 37 28 0,000 0,02260356 0,03010932 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,02260356 0,03009292 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,02260356 0,03007652 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,02260356 0,03006015 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,02260356 0,0300438 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,02260356 0,03002746 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,02260356 0,03001114 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,02260356 0,02999484 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,02260356 0,02997856 ! glutathione metabolic process GO:0006749 42 28 0,000 0,02260356 0,02996229 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,02260356 0,02994604 ! lipid oxidation GO:0034440 48 28 0,000 0,02260356 0,02992981 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,02260356 0,0299136 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,02260356 0,0298974 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,02340164 0,03093626 ! translational initiation GO:0006413 66 29 0,000 0,02340164 0,03091952 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,02340164 0,03090281 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,02340164 0,03088612 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,02340164 0,03086944 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,02340164 0,03085278 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,02340164 0,03083614 ! primary neural tube formation GO:0014020 61 29 0,000 0,02340164 0,03081952 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,02340164 0,03080291 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,02340164 0,03078632 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,02340164 0,03076975 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,02340164 0,0307532 ! somitogenesis GO:0001756 52 29 0,000 0,02340164 0,03073667 ! synaptogenesis GO:0007416 46 29 0,000 0,02340164 0,03072015 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,02340164 0,03070365 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,02340164 0,03068717 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,02340164 0,03067071 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,02340164 0,03065426 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,02419909 0,03168187 ! phenol metabolic process GO:0018958 56 30 0,000 0,02419909 0,0316649 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,02419909 0,03164795 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,02419909 0,03163101 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,02419909 0,0316141 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,02419909 0,0315972 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,02419909 0,03158032 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,02419909 0,03156346 ! acute-phase response GO:0006953 50 30 0,000 0,02419909 0,03154662 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,02419909 0,0315298 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,02419909 0,03151299 ! myofibril assembly GO:0030239 50 30 0,000 0,02419909 0,0314962 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,02419909 0,03147943 ! determination of left/right symmetry GO:0007368 53 30 0,000 0,02419909 0,03146267 ! cell fate determination GO:0001709 64 30 0,000 0,02419909 0,03144594 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,02419909 0,03142922 ! phospholipid transport GO:0015914 65 30 0,000 0,02419909 0,03141252 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,02419909 0,03139584 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,02419909 0,03137918 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,02419909 0,03136253 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,02419909 0,0313459 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,02419909 0,03132929 GO:0048871|multicellular organismal homeostasis, ! regulation of B cell activation GO:0050864 55 30 0,000 0,02419909 0,03131269 ! regulation of coagulation GO:0050818 52 30 0,000 0,02419909 0,03129612 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,0249959 0,03230952 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,0249959 0,03229243 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,0249959 0,03227537 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,0249959 0,03225832 ! cell junction assembly GO:0034329 85 31 0,000 0,0249959 0,03224129 ! regulation of innate immune response GO:0045088 57 31 0,000 0,0249959 0,03222427 ! ovulation cycle process GO:0022602 55 31 0,000 0,0249959 0,03220728 ! peptide transport GO:0015833 60 31 0,000 0,0249959 0,0321903 ! male gonad development GO:0008584 56 31 0,000 0,0249959 0,03217334 ! iron ion homeostasis GO:0055072 60 31 0,000 0,0249959 0,0321564 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,0249959 0,03213947 ! detection of light stimulus GO:0009583 44 31 0,000 0,0249959 0,03212256 ! cellular response to extracellular stimulus GO:0031668 52 31 0,000 0,0249959 0,03210568 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,0249959 0,0320888 ! natural killer cell activation GO:0030101 50 31 0,000 0,0249959 0,03207195 ! ensheathment of neurons GO:0007272 64 31 0,000 0,0249959 0,03205512 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,0249959 0,0320383 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,0249959 0,0320215 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,0249959 0,03200471 ! eye morphogenesis GO:0048592 65 31 0,000 0,0249959 0,03198795 ! response to heat GO:0009408 54 31 0,000 0,0249959 0,0319712 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,0249959 0,03195447 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,02579209 0,03295507 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,02579209 0,03293784 ! collagen metabolic process GO:0032963 49 32 0,000 0,02579209 0,03292063 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,02579209 0,03290344 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,02579209 0,03288627 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,02579209 0,03286911 ! metanephros development GO:0001656 81 32 0,000 0,02579209 0,03285198 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,02579209 0,03283486 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,02579209 0,03281775 ! muscle cell development GO:0055001 52 32 0,000 0,02579209 0,03280067 ! mesoderm formation GO:0001707 73 32 0,000 0,02579209 0,0327836 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,02579209 0,03276656 ! ovulation cycle GO:0042698 57 32 0,000 0,02579209 0,03274953 ! peripheral nervous system development GO:0007422 68 32 0,000 0,02579209 0,03273251 ! BMP signaling pathway GO:0030509 71 32 0,000 0,02579209 0,03271552 ! hindbrain development GO:0030902 65 32 0,000 0,02579209 0,03269854 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,02579209 0,03268158 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,02579209 0,03266464 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,02579209 0,03264771 ! gene silencing GO:0016458 71 32 0,000 0,02579209 0,03263081 ! regulation of pH GO:0006885 56 33 0,000 0,02658766 0,0336199 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,02658766 0,03360251 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,02658766 0,03358513 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,02658766 0,03356778 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,02658766 0,03355044 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,02658766 0,03353312 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,02658766 0,03351581 ! response to ionizing radiation GO:0010212 74 33 0,000 0,02658766 0,03349853 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,02658766 0,03348126 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,02658766 0,03346401 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,02658766 0,03344678 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,02658766 0,03342957 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,02658766 0,03341237 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,02658766 0,03339519 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,02658766 0,03337803 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,02738259 0,03435833 ! glial cell differentiation GO:0010001 67 34 0,000 0,02738259 0,0343407 ! post-embryonic development GO:0009791 76 34 0,000 0,02738259 0,03432308 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,02738259 0,03430547 ! cholesterol transport GO:0030301 62 34 0,000 0,02738259 0,03428789 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,02738259 0,03427033 ! spliceosome assembly GO:0000245 75 34 0,000 0,02738259 0,03425278 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,02738259 0,03423525 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,02738259 0,03421774 ! formation of primary germ layer GO:0001704 76 34 0,000 0,02738259 0,03420024 ! cell fate specification GO:0001708 56 34 0,000 0,02738259 0,03418277 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,02738259 0,03416531 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,02738259 0,03414787 ! adult locomotory behavior GO:0008344 62 34 0,000 0,02738259 0,03413045 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,02738259 0,03411304 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,0281769 0,0350847 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,0281769 0,03506682 ! negative regulation of secretion GO:0051048 68 35 0,000 0,0281769 0,03504897 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,0281769 0,03503113 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,0281769 0,03501331 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,0281769 0,03499551 ! membrane docking GO:0022406 69 35 0,000 0,0281769 0,03497773 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,0281769 0,03495997 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,0281769 0,03494222 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,0281769 0,03492449 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,0281769 0,03490678 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,0281769 0,03488909 ! ceramide metabolic process GO:0006672 72 35 0,000 0,0281769 0,03487141 ! telencephalon development GO:0021537 81 35 0,000 0,0281769 0,03485376 ! sterol transport GO:0015918 63 35 0,000 0,0281769 0,03483612 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,0281769 0,0348185 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,0281769 0,0348009 ! placenta development GO:0001890 53 35 0,000 0,0281769 0,03478331 ! vesicle localization GO:0051648 70 35 0,000 0,0281769 0,03476574 ! regulation of muscle development GO:0048634 82 36 0,000 0,02897058 0,03572698 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,02897058 0,03570895 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,02897058 0,03569094 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,02897058 0,03567295 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,02897058 0,03565498 ! positive regulation of cell development GO:0010720 85 36 0,000 0,02897058 0,03563703 ! protein targeting to membrane GO:0006612 75 36 0,000 0,02897058 0,03561909 ! regulation of proteolysis GO:0030162 77 36 0,000 0,02897058 0,03560118 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,02897058 0,03558328 ! aerobic respiration GO:0009060 56 36 0,000 0,02897058 0,0355654 ! cytokine production GO:0001816 68 36 0,000 0,02897058 0,03554753 ! embryonic organ development GO:0048568 67 36 0,000 0,02897058 0,03552969 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,02897058 0,03551186 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,02897058 0,03549405 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,02976364 0,03644741 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,02976364 0,03642915 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,02976364 0,0364109 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,02976364 0,03639268 ! odontogenesis GO:0042476 74 37 0,000 0,02976364 0,03637448 ! actomyosin structure organization GO:0031032 68 37 0,000 0,02976364 0,03635629 ! cell junction organization GO:0034330 96 37 0,000 0,02976364 0,03633812 ! tissue remodeling GO:0048771 78 37 0,000 0,02976364 0,03631997 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,02976364 0,03630184 ! female gonad development GO:0008585 71 37 0,000 0,02976364 0,03628372 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,02976364 0,03626562 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,02976364 0,03624755 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,02976364 0,03622948 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,02976364 0,03621144 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,03055607 0,03715704 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,03055607 0,03713855 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,03055607 0,03712008 ! organic anion transport GO:0015711 82 38 0,000 0,03055607 0,03710163 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,03055607 0,0370832 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,03055607 0,03706479 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,03055607 0,03704639 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,03055607 0,03702802 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,03055607 0,03700966 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,03055607 0,03699132 ! regulation of protein stability GO:0031647 77 38 0,000 0,03055607 0,036973 ! spermatid development GO:0007286 69 38 0,000 0,03055607 0,0369547 ! glycogen metabolic process GO:0005977 63 38 0,000 0,03055607 0,03693641 ! pigment metabolic process GO:0042440 87 38 0,000 0,03055607 0,03691814 ! cellular response to insulin stimulus GO:0032869 85 38 0,000 0,03055607 0,03689989 ! neural tube formation GO:0001841 79 38 0,000 0,03055607 0,03688166 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,03134788 0,0378187 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,03134788 0,03780003 ! negative regulation of binding GO:0051100 71 39 0,000 0,03134788 0,03778139 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,03134788 0,03776276 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,03134788 0,03774414 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,03134788 0,03772555 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,03134788 0,03770698 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,03134788 0,03768842 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,03134788 0,03766988 ! positive regulation of leukocyte proliferation GO:0070665 70 39 0,000 0,03134788 0,03765136 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,03134788 0,03763286 ! glucan metabolic process GO:0044042 64 39 0,000 0,03134788 0,03761438 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,03213906 0,03854478 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 0,000 0,03213906 0,03852587 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,03213906 0,03850698 ! learning GO:0007612 82 40 0,000 0,03213906 0,0384881 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,03213906 0,03846924 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,03213906 0,0384504 ! lipid homeostasis GO:0055088 75 40 0,000 0,03213906 0,03843158 ! mismatch repair GO:0006298 58 40 0,000 0,03213906 0,03841278 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,03213906 0,038394 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,03213906 0,03837523 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,03213906 0,03835649 ! RNA export from nucleus GO:0006405 61 41 0,000 0,03292962 0,03928079 ! mRNA catabolic process GO:0006402 79 41 0,000 0,03292962 0,03926162 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,03292962 0,03924247 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,03292962 0,03922333 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,03292962 0,03920422 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,03292962 0,03918512 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,03292962 0,03916605 ! gliogenesis GO:0042063 91 41 0,000 0,03292962 0,03914699 ! feeding behavior GO:0007631 69 41 0,000 0,03292962 0,03912795 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,03292962 0,03910892 ! mesenchymal cell development GO:0014031 94 41 0,000 0,03292962 0,03908992 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,03292962 0,03907094 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,03292962 0,03905197 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,03292962 0,03903302 ! spermatid differentiation GO:0048515 73 41 0,000 0,03292962 0,03901409 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,03292962 0,03899518 ! RNA modification GO:0009451 64 41 0,000 0,03292962 0,03897629 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,03371955 0,03989195 ! ear morphogenesis GO:0042471 64 42 0,000 0,03371955 0,03987264 ! organic ether metabolic process GO:0018904 59 42 0,000 0,03371955 0,03985335 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,03371955 0,03983408 ! regulation of intracellular protein transport GO:0033157 86 42 0,000 0,03371955 0,03981482 ! T cell differentiation GO:0030217 93 42 0,000 0,03371955 0,03979559 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,03371955 0,03977637 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,03371955 0,03975718 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,03371955 0,039738 ! regulation of protein secretion GO:0050708 77 42 0,000 0,03371955 0,03971884 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,03371955 0,0396997 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,03371955 0,03968057 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,03450886 0,04058987 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 0,000 0,03450886 0,04057033 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,03450886 0,04055082 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,03450886 0,04053132 ! regulation of tube size GO:0035150 76 43 0,000 0,03450886 0,04051185 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,03450886 0,04049239 ! glucose transport GO:0015758 66 43 0,000 0,03450886 0,04047295 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,03450886 0,04045353 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,03450886 0,04043413 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,03450886 0,04041474 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,03450886 0,04039538 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,03450886 0,04037603 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,03450886 0,0403567 ! segmentation GO:0035282 78 43 0,000 0,03450886 0,04033739 ! ion transmembrane transport GO:0034220 79 43 0,000 0,03450886 0,0403181 ! neuron migration GO:0001764 85 43 0,000 0,03450886 0,04029883 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,03450886 0,04027958 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,03529755 0,04118048 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,03529755 0,04116082 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,03529755 0,04114118 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,03529755 0,04112157 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,03529755 0,04110196 ! hexose transport GO:0008645 68 44 0,000 0,03529755 0,04108238 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,03529755 0,04106282 ! striated muscle contraction GO:0006941 85 44 0,000 0,03529755 0,04104328 ! phagocytosis GO:0006909 105 44 0,000 0,03529755 0,04102375 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,03529755 0,04100424 ! double-strand break repair GO:0006302 85 44 0,000 0,03529755 0,04098475 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,03608562 0,04187989 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,03608562 0,04186 ! regulation of epithelial cell proliferation GO:0050678 122 45 0,000 0,03608562 0,04184014 ! induction of apoptosis by intracellular signals GO:0008629 95 45 0,000 0,03608562 0,04182029 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,03608562 0,04180046 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,03608562 0,04178065 ! biopolymer methylation GO:0043414 91 45 0,000 0,03608562 0,04176086 ! B cell differentiation GO:0030183 124 45 0,000 0,03608562 0,04174108 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,03608562 0,04172133 ! female gamete generation GO:0007292 71 45 0,000 0,03608562 0,04170159 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,03608562 0,04168188 ! polyol metabolic process GO:0019751 77 45 0,000 0,03608562 0,04166218 ! developmental growth GO:0048589 88 45 0,000 0,03608562 0,0416425 ! maintenance of location in cell GO:0051651 101 45 0,000 0,03608562 0,04162284 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,03687307 0,04251104 ! glycolysis GO:0006096 71 46 0,000 0,03687307 0,04249099 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 0,000 0,03687307 0,04247096 ! regulation of gene-specific transcription GO:0032583 102 46 0,000 0,03687307 0,04245094 ! leukocyte migration GO:0050900 75 46 0,000 0,03687307 0,04243095 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,03687307 0,04241097 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,03687307 0,04239101 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,03687307 0,04237107 ! pigmentation GO:0043473 103 46 0,000 0,03687307 0,04235115 ! cell growth GO:0016049 90 46 0,000 0,03687307 0,04233125 ! positive regulation of protein transport GO:0051222 80 46 0,000 0,03687307 0,04231137 ! neural tube development GO:0021915 91 47 0,000 0,03765989 0,04319395 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,03765989 0,04317368 ! response to insulin stimulus GO:0032868 98 47 0,000 0,03765989 0,04315343 ! positive regulation of defense response GO:0031349 88 48 0,000 0,03844609 0,04403366 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,03844609 0,04401303 ! mitochondrial transport GO:0006839 94 48 0,000 0,03844609 0,04399241 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,03844609 0,04397182 ! cellular component disassembly GO:0022411 89 48 0,000 0,03844609 0,04395124 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,03844609 0,04393068 ! endosome transport GO:0016197 127 48 0,000 0,03844609 0,04391015 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,03844609 0,04388963 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,03844609 0,04386913 ! male sex differentiation GO:0046661 93 48 0,000 0,03844609 0,04384865 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,03844609 0,04382819 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,03844609 0,04380774 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,03844609 0,04378732 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,03844609 0,04376692 ! methylation GO:0032259 97 48 0,000 0,03844609 0,04374653 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,03923168 0,04461964 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,03923168 0,04459888 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,03923168 0,04457813 ! JNK cascade GO:0007254 106 49 0,000 0,03923168 0,04455741 ! regulation of mast cell proliferation GO:0070666 89 49 0,000 0,03923168 0,0445367 ! protein homooligomerization GO:0051260 84 49 0,000 0,03923168 0,04451602 ! regulation of action potential GO:0001508 102 50 0,000 0,04001664 0,04538563 ! regulation of ion transport GO:0043269 86 50 0,000 0,04001664 0,04536457 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,04001664 0,04534353 ! endocrine system development GO:0035270 109 50 0,000 0,04001664 0,04532251 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,04001664 0,04530151 ! activation of caspase activity GO:0006919 95 50 0,000 0,04001664 0,04528052 ! regulation of ossification GO:0030278 123 50 0,000 0,04001664 0,04525956 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,04001664 0,04523862 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,04001664 0,04521769 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,04001664 0,04519679 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,04001664 0,0451759 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,04001664 0,04515503 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,04080098 0,04601884 ! viral infectious cycle GO:0019058 104 51 0,000 0,04080098 0,0459976 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,04080098 0,04597639 ! peptide metabolic process GO:0006518 80 51 0,000 0,04080098 0,04595519 ! response to temperature stimulus GO:0009266 84 51 0,000 0,04080098 0,04593401 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,04080098 0,04591285 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,04080098 0,04589171 ! positive regulation of binding GO:0051099 88 52 0,000 0,04158471 0,0467517 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,04158471 0,0467302 ! Notch signaling pathway GO:0007219 111 52 0,000 0,04158471 0,04670871 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,04158471 0,04668724 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,04158471 0,0466658 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,04158471 0,04664437 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,04158471 0,04662297 ! excretion GO:0007588 87 52 0,000 0,04158471 0,04660158 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,04158471 0,04658021 ! histone modification GO:0016570 104 52 0,000 0,04158471 0,04655887 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,04158471 0,04653754 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,04158471 0,04651623 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,04158471 0,04649494 ! amino acid activation GO:0043038 98 52 0,000 0,04158471 0,04647367 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,04236782 0,0473272 ! positive regulation of growth GO:0045927 96 53 0,000 0,04236782 0,04730556 ! inner ear development GO:0048839 89 53 0,000 0,04236782 0,04728395 ! chromatin remodeling GO:0006338 122 53 0,000 0,04236782 0,04726236 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,04236782 0,04724079 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,04236782 0,04721924 ! vesicle organization GO:0016050 127 53 0,000 0,04236782 0,04719771 ! regulation of leukocyte proliferation GO:0070663 97 53 0,000 0,04236782 0,0471762 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,04236782 0,0471547 ! cartilage development GO:0051216 99 53 0,000 0,04236782 0,04713323 ! synapse organization GO:0050808 102 53 0,000 0,04236782 0,04711178 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,04315031 0,04796005 ! regulation of translational initiation GO:0006446 87 54 0,000 0,04315031 0,04793824 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,04315031 0,04791645 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,04315031 0,04789468 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 0,000 0,04315031 0,04787293 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,04315031 0,0478512 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,04315031 0,04782949 ! membrane fusion GO:0006944 122 54 0,000 0,04315031 0,0478078 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,04315031 0,04778613 ! covalent chromatin modification GO:0016569 115 54 0,000 0,04315031 0,04776448 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,04315031 0,04774284 ! regulation of cell shape GO:0008360 142 54 0,000 0,04315031 0,04772123 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,04315031 0,04769964 ! RNA catabolic process GO:0006401 103 55 0,000 0,04393218 0,04854198 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,04393218 0,04852003 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,04393218 0,04849811 ! cell recognition GO:0008037 98 55 0,000 0,04393218 0,0484762 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,04393218 0,04845432 ! cell maturation GO:0048469 107 55 0,000 0,04393218 0,04843245 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,04393218 0,0484106 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,04471343 0,04924929 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,04471343 0,04922709 ! glucose catabolic process GO:0006007 88 56 0,000 0,04471343 0,04920492 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,04471343 0,04918276 ! RNA elongation GO:0006354 90 56 0,000 0,04471343 0,04916063 ! chloride transport GO:0006821 102 57 0,000 0,04549407 0,04999641 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,04549407 0,04997393 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,04549407 0,04995147 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 131 57 0,000 0,04549407 0,04992903 ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,04549407 0,04990661 ! heart morphogenesis GO:0003007 105 57 0,000 0,04549407 0,04988421 ! regulation of intracellular transport GO:0032386 108 57 0,000 0,04549407 0,04986183 ! positive regulation of cell migration GO:0030335 137 58 0,000 0,0462741 0,050694 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,0462741 0,05067127 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,0462741 0,05064857 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,0462741 0,05062589 ! aging GO:0007568 112 58 0,000 0,0462741 0,05060323 ! gastrulation GO:0007369 122 58 0,000 0,0462741 0,05058059 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,0462741 0,05055797 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,0462741 0,05053537 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,0462741 0,05051279 ! maintenance of location GO:0051235 124 58 0,000 0,0462741 0,05049023 ! nuclear export GO:0051168 110 59 0,000 0,0470535 0,05131773 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,04783229 0,05214382 ! lipid modification GO:0030258 112 60 0,000 0,04783229 0,05212056 ! DNA catabolic process GO:0006308 94 60 0,000 0,04783229 0,05209732 ! regulation of endocytosis GO:0030100 104 60 0,000 0,04783229 0,05207411 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,04783229 0,05205091 ! adult behavior GO:0030534 104 60 0,000 0,04783229 0,05202774 ! kidney development GO:0001822 133 60 0,000 0,04783229 0,05200458 ! positive regulation of secretion GO:0051047 110 61 0,000 0,04861047 0,05282713 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,04861047 0,05280364 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,04861047 0,05278017 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,04861047 0,05275672 ! regulation of heart contraction GO:0008016 123 61 0,000 0,04861047 0,0527333 ! camera-type eye development GO:0043010 126 61 0,000 0,04861047 0,05270989 ! proton transport GO:0015992 117 61 0,000 0,04861047 0,05268651 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,04861047 0,05266314 ! viral reproductive process GO:0022415 132 62 0,000 0,04938804 0,05348181 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,04938804 0,05345812 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,04938804 0,05343444 ! tRNA processing GO:0008033 102 62 0,000 0,04938804 0,05341079 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,04938804 0,05338716 ! mesoderm development GO:0007498 128 63 0,000 0,05016499 0,05420304 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,05016499 0,05417907 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,05016499 0,05415513 ! hydrogen transport GO:0006818 121 64 0,000 0,05094132 0,05496893 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,05094132 0,05494466 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,05094132 0,05492041 ! protein amino acid autophosphorylation GO:0046777 157 64 0,000 0,05094132 0,05489619 ! response to peptide hormone stimulus GO:0043434 129 64 0,000 0,05094132 0,05487198 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,05171705 0,05568301 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,05171705 0,05565848 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,05171705 0,05563397 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,05171705 0,05560948 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,05171705 0,05558502 ! positive regulation of cell motion GO:0051272 157 65 0,000 0,05171705 0,05556058 ! ear development GO:0043583 114 66 0,000 0,05249216 0,0563685 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,05249216 0,05634374 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,05249216 0,05631899 ! gonad development GO:0008406 115 66 0,000 0,05249216 0,05629427 ! steroid hormone receptor signaling pathway GO:0030518 146 66 0,000 0,05249216 0,05626957 ! negative regulation of cell growth GO:0030308 142 67 0,000 0,05326666 0,05707476 ! activation of MAPK activity GO:0000187 124 67 0,000 0,05326666 0,05704974 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,05326666 0,05702474 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,05326666 0,05699976 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,05326666 0,0569748 ! secondary metabolic process GO:0019748 125 67 0,000 0,05326666 0,05694987 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,05326666 0,05692496 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,05404055 0,05772674 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,05404055 0,05770151 ! hexose catabolic process GO:0019320 113 68 0,000 0,05404055 0,05767631 ! extracellular matrix organization GO:0030198 146 68 0,000 0,05404055 0,05765112 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,05404055 0,05762596 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,05404055 0,05760081 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,05404055 0,05757569 ! viral reproduction GO:0016032 142 68 0,000 0,05404055 0,05755059 ! regulation of lipase activity GO:0060191 137 68 0,000 0,05404055 0,05752552 ! adaptive immune response GO:0002250 126 68 0,000 0,05404055 0,05750046 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cell projection assembly GO:0030031 138 68 0,000 0,05404055 0,05747543 ! negative regulation of cell size GO:0045792 144 69 0,000 0,05481383 0,05827249 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,05481383 0,05824714 ! negative regulation of protein kinase activity GO:0006469 144 69 0,000 0,05481383 0,05822182 ! lung development GO:0030324 165 69 0,000 0,05481383 0,05819652 ! urogenital system development GO:0001655 149 69 0,000 0,05481383 0,05817123 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,05481383 0,05814598 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 0,000 0,05481383 0,05812074 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,05481383 0,05809552 ! developmental maturation GO:0021700 128 69 0,000 0,05481383 0,05807033 ! single fertilization GO:0007338 83 69 0,000 0,05481383 0,05804516 ! negative regulation of kinase activity GO:0033673 145 70 0,000 0,0555865 0,05883787 ! cell redox homeostasis GO:0045454 114 70 0,000 0,0555865 0,05881239 ! germ cell development GO:0007281 133 70 0,000 0,0555865 0,05878693 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,0555865 0,05876149 ! cell cycle checkpoint GO:0000075 145 71 0,000 0,05635855 0,05955188 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,05635855 0,05952613 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,05635855 0,05950041 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 0,000 0,05635855 0,05947471 ! appendage morphogenesis GO:0035107 150 72 0,000 0,05713 0,06026278 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,05713 0,06023677 ! respiratory tube development GO:0030323 171 72 0,000 0,05713 0,06021078 ! actin filament organization GO:0007015 167 72 0,000 0,05713 0,06018482 ! B cell activation GO:0042113 179 72 0,000 0,05713 0,06015888 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,05713 0,06013296 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,05713 0,06010706 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,05713 0,06008119 ! appendage development GO:0048736 151 73 0,000 0,05790084 0,06086565 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,05790084 0,06083947 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,05790084 0,06081331 ! regulation of immune effector process GO:0002697 156 73 0,000 0,05790084 0,06078718 ! acute inflammatory response GO:0002526 118 74 0,000 0,05867107 0,06156935 ! amino acid transport GO:0006865 148 74 0,000 0,05867107 0,06154291 ! regulation of caspase activity GO:0043281 136 74 0,000 0,05867107 0,0615165 ! negative regulation of transferase activity GO:0051348 155 74 0,000 0,05867107 0,06149011 ! respiratory system development GO:0060541 175 74 0,000 0,05867107 0,06146374 ! regulation of transcription factor activity GO:0051090 137 75 0,000 0,0594407 0,0622433 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 143 75 0,000 0,0594407 0,06221663 ! reproductive structure development GO:0048608 131 75 0,000 0,0594407 0,06218999 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,0594407 0,06216337 ! eye development GO:0001654 155 75 0,000 0,0594407 0,06213677 ! axon guidance GO:0007411 162 75 0,000 0,0594407 0,06211019 ! rhythmic process GO:0048511 142 75 0,000 0,0594407 0,06208364 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,06020971 0,06285997 ! learning or memory GO:0007611 161 76 0,000 0,06020971 0,06283312 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,06020971 0,06280629 ! regulation of blood pressure GO:0008217 134 76 0,000 0,06020971 0,06277948 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,06020971 0,0627527 ! amine catabolic process GO:0009310 136 77 0,000 0,06097812 0,06352646 ! neurotransmitter transport GO:0006836 142 77 0,000 0,06097812 0,06349938 ! phosphoinositide metabolic process GO:0030384 146 77 0,000 0,06097812 0,06347233 ! regulation of endopeptidase activity GO:0052548 141 77 0,000 0,06097812 0,0634453 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,06097812 0,06341829 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,06097812 0,0633913 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,06097812 0,06336434 ! regulation of catabolic process GO:0009894 173 77 0,000 0,06097812 0,06333739 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,06174592 0,06410765 ! antigen processing and presentation GO:0019882 117 78 0,000 0,06174592 0,06408041 ! fertilization GO:0009566 99 78 0,000 0,06174592 0,0640532 ! positive regulation of lymphocyte activation GO:0051251 142 78 0,000 0,06174592 0,06402602 ! blood coagulation GO:0007596 151 79 0,000 0,06251312 0,06479404 GO:0050817|coagulation, ! steroid biosynthetic process GO:0006694 146 79 0,000 0,06251312 0,06476656 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,06251312 0,06473911 ! protein oligomerization GO:0051259 149 79 0,000 0,06251312 0,06471167 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,06251312 0,06468427 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,06327971 0,06544976 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,06327971 0,06542206 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,06327971 0,06539439 ! muscle cell differentiation GO:0042692 178 81 0,000 0,0640457 0,06615798 ! response to hypoxia GO:0001666 178 81 0,000 0,0640457 0,06613002 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,0640457 0,06610208 ! regulation of peptidase activity GO:0052547 150 82 0,000 0,06481108 0,06686379 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,06481108 0,06683557 ! protein import into nucleus GO:0006606 174 82 0,000 0,06481108 0,06680737 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,06557585 0,06756719 ! exocytosis GO:0006887 153 83 0,000 0,06557585 0,0675387 ! response to drug GO:0042493 149 83 0,000 0,06557585 0,06751024 ! response to oxygen levels GO:0070482 183 83 0,000 0,06557585 0,0674818 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,06557585 0,06745339 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,06557585 0,067425 ! nuclear import GO:0051170 177 83 0,000 0,06557585 0,06739664 ! inorganic anion transport GO:0015698 156 83 0,000 0,06557585 0,06736829 ! T cell activation GO:0042110 189 84 0,000 0,06634002 0,06812471 ! response to nutrient GO:0007584 135 84 0,000 0,06634002 0,06809608 ! digestion GO:0007586 130 84 0,000 0,06634002 0,06806748 ! hemostasis GO:0007599 165 85 0,000 0,06710359 0,06882203 ! negative regulation of transport GO:0051051 164 85 0,000 0,06710359 0,06879315 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,06710359 0,06876429 ! negative regulation of growth GO:0045926 168 85 0,000 0,06710359 0,06873546 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,06710359 0,06870665 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,06710359 0,06867787 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,06710359 0,06864911 ! cellular response to hormone stimulus GO:0032870 182 85 0,000 0,06710359 0,06862037 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,06786656 0,06937155 ! regulation of lyase activity GO:0051339 169 86 0,000 0,06786656 0,06934253 ! positive regulation of cell activation GO:0050867 161 86 0,000 0,06786656 0,06931354 GO:0002696|positive regulation of leukocyte activation, ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,06862892 0,07006287 ! mitochondrion organization GO:0007005 159 87 0,000 0,06862892 0,07003361 ! alcohol catabolic process GO:0046164 142 87 0,000 0,06862892 0,07000436 ! nucleosome assembly GO:0006334 126 87 0,000 0,06862892 0,06997515 ! regulation of protein transport GO:0051223 165 87 0,000 0,06862892 0,06994595 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 143 88 0,000 0,06939068 0,07069284 ! amine biosynthetic process GO:0009309 146 88 0,000 0,06939068 0,07066337 ! sensory perception of smell GO:0007608 117 88 0,000 0,06939068 0,07063393 ! chromatin assembly GO:0031497 128 88 0,000 0,06939068 0,07060451 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,06939068 0,07057512 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,07015184 0,07131958 ! regulation of DNA binding GO:0051101 167 89 0,000 0,07015184 0,07128991 ! tube morphogenesis GO:0035239 194 89 0,000 0,07015184 0,07126027 ! cellular defense response GO:0006968 123 89 0,000 0,07015184 0,07123065 ! protein localization in nucleus GO:0034504 192 89 0,000 0,07015184 0,07120106 ! regulation of neurological system process GO:0031644 175 89 0,000 0,07015184 0,07117149 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,0709124 0,07191324 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,07167236 0,07265376 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! ossification GO:0001503 205 91 0,000 0,07167236 0,07262363 ! gland development GO:0048732 220 91 0,000 0,07167236 0,07259352 ! defense response to bacterium GO:0042742 112 91 0,000 0,07167236 0,07256343 ! bone development GO:0060348 206 92 0,000 0,07243171 0,07330186 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,07243171 0,0732715 ! regulation of cell adhesion GO:0030155 241 92 0,000 0,07243171 0,07324117 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,07319047 0,07397779 ! amine transport GO:0015837 181 93 0,000 0,07319047 0,0739472 ! positive regulation of MAP kinase activity GO:0043406 174 93 0,000 0,07319047 0,07391663 ! vitamin metabolic process GO:0006766 153 93 0,000 0,07319047 0,07388608 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,07394863 0,07462061 ! female pregnancy GO:0007565 166 94 0,000 0,07394863 0,0745898 ! sterol metabolic process GO:0016125 166 94 0,000 0,07394863 0,07455902 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,07394863 0,07452826 ! regulation of membrane potential GO:0042391 179 94 0,000 0,07394863 0,07449753 ! regulation of defense response GO:0031347 171 95 0,000 0,07470619 0,07522969 ! nucleosome organization GO:0034728 143 95 0,000 0,07470619 0,07519869 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,07470619 0,07516772 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,07470619 0,07513677 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,07470619 0,07510585 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,07470619 0,07507496 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,07470619 0,07504409 ! sex differentiation GO:0007548 171 96 0,000 0,07546315 0,07577332 ! regulation of T cell activation GO:0050863 175 96 0,000 0,07546315 0,07574219 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,07621951 0,07646993 ! transcription initiation GO:0006352 171 97 0,000 0,07621951 0,07643854 ! regulation of protein localization GO:0032880 188 97 0,000 0,07621951 0,07640717 ! leukocyte differentiation GO:0002521 232 98 0,000 0,07697528 0,07713315 ! forebrain development GO:0030900 210 98 0,000 0,07697528 0,07710152 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,07697528 0,07706992 ! skeletal muscle tissue development GO:0007519 223 100 0,000 0,07848502 0,07854933 GO:0060538|skeletal muscle organ development, ! mRNA transport GO:0051028 185 100 0,000 0,07848502 0,07851716 ! hormone metabolic process GO:0042445 171 100 0,000 0,07848502 0,07848502