pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-b1/out-0.05-06-0.01-300-run-b1//th1-pval-1e-01-08-th2-pval-1e-02-02-th3-pval-1e-01-01-run-b1/go_data/2305-2-real-Loi_GPL96-GPL97-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! interphase of mitotic cell cycle GO:0051329 209 95 3,000 4,51E-08 1,085E-04 ! interphase GO:0051325 213 98 3,000 5,114E-08 6,152E-05 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 2,000 7,266E-07 5,827E-04 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 2,000 1,397E-06 8,403E-04 ! negative regulation of protein ubiquitination GO:0031397 9 5 1,000 1,454E-06 6,998E-04 ! activation of Ras GTPase activity GO:0032856 10 5 1,000 1,454E-06 5,832E-04 GO:0032862|activation of Rho GTPase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 2,000 2,387E-06 8,204E-04 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 2,000 2,495E-06 7,503E-04 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 2,000 2,838E-06 7,587E-04 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 2,000 2,838E-06 6,828E-04 ! positive regulation of ligase activity GO:0051351 124 77 2,000 3,477E-06 7,605E-04 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 2,000 3,757E-06 7,533E-04 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 4,07E-06 7,532E-04 ! regulation of focal adhesion formation GO:0051893 22 8 1,000 4,07E-06 6,994E-04 ! regulation of ligase activity GO:0051340 142 84 2,000 4,522E-06 7,253E-04 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 1,000 5,231E-06 7,866E-04 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 2,000 6,146E-06 8,698E-04 GO:0010498|proteasomal protein catabolic process, ! regulation of phosphatase activity GO:0010921 28 10 1,000 6,537E-06 8,738E-04 ! regulation of stress fiber formation GO:0051492 30 10 1,000 6,537E-06 8,278E-04 ! positive regulation of Rho GTPase activity GO:0032321 24 10 1,000 6,537E-06 7,865E-04 ! regulation of actin filament bundle formation GO:0032231 33 11 1,000 7,988E-06 9,152E-04 ! positive regulation of Ras GTPase activity GO:0032320 35 13 1,000 1,132E-05 1,238E-03 ! positive regulation of GTPase activity GO:0043547 36 14 1,000 1,321E-05 1,382E-03 ! regulation of protein ubiquitination GO:0031396 25 16 1,000 1,741E-05 1,745E-03 ! regulation of dephosphorylation GO:0035303 43 16 1,000 1,741E-05 1,676E-03 ! cellular response to unfolded protein GO:0034620 33 19 1,000 2,479E-05 2,294E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! negative regulation of translation GO:0017148 29 20 1,000 2,754E-05 2,454E-03 ! regulation of Rho GTPase activity GO:0032319 43 21 1,000 3,043E-05 2,615E-03 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 3,665E-05 3,041E-03 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 3,665E-05 2,939E-03 GO:0010810|regulation of cell-substrate adhesion, ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 4,344E-05 3,371E-03 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 4,344E-05 3,266E-03 ! fat cell differentiation GO:0045444 50 27 1,000 5,08E-05 3,704E-03 ! negative regulation of protein modification process GO:0031400 60 28 1,000 5,47E-05 3,871E-03 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 5,47E-05 3,76E-03 ! RNA export from nucleus GO:0006405 56 37 1,000 9,618E-05 6,428E-03 ! response to insulin stimulus GO:0032868 95 46 1,000 1,492E-04 9,7E-03 ! response to calcium ion GO:0051592 81 47 1,000 1,558E-04 9,862E-03 ! positive regulation of cell cycle GO:0045787 89 48 1,000 1,625E-04 0,01002495 ! response to UV GO:0009411 104 53 1,000 1,983E-04 0,01192742 ! nuclear export GO:0051168 97 55 1,000 2,136E-04 0,01253451 ! response to peptide hormone stimulus GO:0043434 122 61 1,000 2,629E-04 0,01505878 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 1,000 3,663E-04 0,02049382 ! regulation of actin cytoskeleton organization GO:0032956 149 74 1,000 3,869E-04 0,02115486 ! regulation of actin filament-based process GO:0032970 152 77 1,000 4,188E-04 0,02239297 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 4,408E-04 0,0230564 ! response to metal ion GO:0010038 140 80 1,000 4,52E-04 0,02313933 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 4,634E-04 0,02322572 GO:0045937|positive regulation of phosphate metabolic process, ! response to unfolded protein GO:0006986 131 85 1,000 5,101E-04 0,02504684 ! response to inorganic substance GO:0010035 153 86 1,000 5,221E-04 0,02512477 ! positive regulation of protein modification process GO:0031401 136 88 1,000 5,466E-04 0,02578661 ! regulation of cell adhesion GO:0030155 212 89 1,000 5,59E-04 0,02586638 ! response to protein stimulus GO:0051789 149 91 1,000 5,843E-04 0,02652663 ! regulation of Rho protein signal transduction GO:0035023 213 95 1,000 6,366E-04 0,02836268 ! cell cycle arrest GO:0007050 213 100 1,000 7,049E-04 0,03083767 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 1,991E-03 0,08553224 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 1,991E-03 0,08403168 ! positive regulation of helicase activity GO:0051096 11 5 0,000 1,991E-03 0,08258286 ! neuron fate determination GO:0048664 7 5 0,000 1,991E-03 0,08118315 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 1,991E-03 0,0798301 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 1,991E-03 0,07852141 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 1,991E-03 0,07725493 ! polyol transport GO:0015791 12 5 0,000 1,991E-03 0,07602866 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 1,991E-03 0,07484071 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 1,991E-03 0,07368932 ! response to superoxide GO:0000303 10 5 0,000 1,991E-03 0,07257281 ! negative regulation of bone resorption GO:0045779 10 5 0,000 1,991E-03 0,07148964 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 1,991E-03 0,07043832 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 1,991E-03 0,06941747 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 1,991E-03 0,0684258 ! female meiosis GO:0007143 7 5 0,000 1,991E-03 0,06746205 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 1,991E-03 0,06652508 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 1,991E-03 0,06561378 ! cobalt ion transport GO:0006824 11 5 0,000 1,991E-03 0,0647271 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 1,991E-03 0,06386408 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 1,991E-03 0,06302376 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 1,991E-03 0,06220527 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 1,991E-03 0,06140777 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 1,991E-03 0,06063045 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 1,991E-03 0,05987257 ! embryonic camera-type eye development GO:0031076 10 5 0,000 1,991E-03 0,0591334 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 1,991E-03 0,05841226 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 1,991E-03 0,0577085 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 1,991E-03 0,0570215 ! adaptation of signaling pathway GO:0022401 7 5 0,000 1,991E-03 0,05635066 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 1,991E-03 0,05569542 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 1,991E-03 0,05505524 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 1,991E-03 0,05442961 ! negative chemotaxis GO:0050919 14 5 0,000 1,991E-03 0,05381804 ! positive regulation of histone modification GO:0031058 5 5 0,000 1,991E-03 0,05322006 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 1,991E-03 0,05263523 ! sensory perception of bitter taste GO:0050913 7 5 0,000 1,991E-03 0,05206311 ! behavioral response to pain GO:0048266 9 5 0,000 1,991E-03 0,05150329 ! clathrin coat assembly GO:0048268 14 5 0,000 1,991E-03 0,05095538 ! Notch receptor processing GO:0007220 8 5 0,000 1,991E-03 0,05041901 ! regulation of dopamine uptake GO:0051584 9 5 0,000 1,991E-03 0,04989381 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 1,991E-03 0,04937944 ! micturition GO:0060073 9 5 0,000 1,991E-03 0,04887557 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 1,991E-03 0,04838188 ! copulation GO:0007620 9 5 0,000 1,991E-03 0,04789806 ! glial cell fate commitment GO:0021781 13 5 0,000 1,991E-03 0,04742382 ! protein maturation by protein folding GO:0022417 13 5 0,000 1,991E-03 0,04695888 ! spermidine metabolic process GO:0008216 7 5 0,000 1,991E-03 0,04650297 ! regulation of potassium ion transport GO:0043266 10 5 0,000 1,991E-03 0,04605582 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 1,991E-03 0,0456172 ! apoptotic cell clearance GO:0043277 20 5 0,000 1,991E-03 0,04518685 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 1,991E-03 0,04476454 ! lipoprotein particle clearance GO:0034381 10 5 0,000 1,991E-03 0,04435005 ! grooming behavior GO:0007625 6 5 0,000 1,991E-03 0,04394317 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 1,991E-03 0,04354369 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 1,991E-03 0,0431514 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 1,991E-03 0,04276612 ! response to protozoan GO:0001562 10 5 0,000 1,991E-03 0,04238766 ! positive regulation of glycolysis GO:0045821 14 5 0,000 1,991E-03 0,04201584 ! lymph vessel development GO:0001945 10 5 0,000 1,991E-03 0,04165048 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 1,991E-03 0,04129143 ! endochondral ossification GO:0001958 16 5 0,000 1,991E-03 0,04093851 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 1,991E-03 0,04059157 ! parathyroid gland development GO:0060017 13 5 0,000 1,991E-03 0,04025047 ! anagen GO:0042640 6 5 0,000 1,991E-03 0,03991505 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 1,991E-03 0,03958517 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 1,991E-03 0,0392607 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 1,991E-03 0,03894151 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 1,991E-03 0,03862747 ! dorsal spinal cord development GO:0021516 7 5 0,000 1,991E-03 0,03831845 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 1,991E-03 0,03801433 ! sphingoid catabolic process GO:0046521 6 5 0,000 1,991E-03 0,03771501 ! skeletal myofibril assembly GO:0014866 10 5 0,000 1,991E-03 0,03742036 ! smooth muscle tissue development GO:0048745 28 5 0,000 1,991E-03 0,03713028 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 1,991E-03 0,03684466 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 1,991E-03 0,0365634 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 1,991E-03 0,03628641 ! cardiac muscle fiber development GO:0048739 10 5 0,000 1,991E-03 0,03601358 ! transepithelial chloride transport GO:0030321 9 5 0,000 1,991E-03 0,03574482 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 1,991E-03 0,03548004 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 1,991E-03 0,03521916 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 1,991E-03 0,03496209 ! neutrophil mediated immunity GO:0002446 7 5 0,000 1,991E-03 0,03470874 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 1,991E-03 0,03445903 ! histidine catabolic process GO:0006548 6 5 0,000 1,991E-03 0,0342129 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 1,991E-03 0,03397025 ! microvillus organization GO:0032528 7 5 0,000 1,991E-03 0,03373103 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 1,991E-03 0,03349514 ! L-serine biosynthetic process GO:0006564 6 5 0,000 1,991E-03 0,03326254 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 1,991E-03 0,03303314 ! tryptophan metabolic process GO:0006568 9 5 0,000 1,991E-03 0,03280689 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 1,991E-03 0,03258371 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 1,991E-03 0,03236355 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 1,991E-03 0,03214635 ! polyol catabolic process GO:0046174 7 5 0,000 1,991E-03 0,03193204 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 1,991E-03 0,03172057 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 1,991E-03 0,03151188 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 1,991E-03 0,03130592 ! muscle cell migration GO:0014812 8 5 0,000 1,991E-03 0,03110263 ! mitochondrial fission GO:0000266 8 5 0,000 1,991E-03 0,03090197 ! sister chromatid cohesion GO:0007062 12 5 0,000 1,991E-03 0,03070388 ! mRNA transcription GO:0009299 9 5 0,000 1,991E-03 0,03050832 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 1,991E-03 0,03031523 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 1,991E-03 0,03012456 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 1,991E-03 0,02993629 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 1,991E-03 0,02975035 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 1,991E-03 0,0295667 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 1,991E-03 0,02938531 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 1,991E-03 0,02920613 ! response to food GO:0032094 6 5 0,000 1,991E-03 0,02902913 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 1,991E-03 0,02885425 ! positive regulation of transporter activity GO:0032411 8 5 0,000 1,991E-03 0,02868147 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 1,991E-03 0,02851075 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 1,991E-03 0,02834205 ! paraxial mesoderm development GO:0048339 14 5 0,000 1,991E-03 0,02817533 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 1,991E-03 0,02801056 ! forebrain neuron development GO:0021884 13 5 0,000 1,991E-03 0,02784771 ! lipoprotein catabolic process GO:0042159 11 5 0,000 1,991E-03 0,02768674 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 1,991E-03 0,02752762 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 1,991E-03 0,02737032 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 1,991E-03 0,02721481 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 1,991E-03 0,02706105 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 1,991E-03 0,02690902 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 1,991E-03 0,02675869 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 1,991E-03 0,02661003 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 1,991E-03 0,02646302 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 1,991E-03 0,02631761 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 1,991E-03 0,0261738 ! basic amino acid transport GO:0015802 11 5 0,000 1,991E-03 0,02603155 ! cellular glucose homeostasis GO:0001678 5 5 0,000 1,991E-03 0,02589084 ! early endosome to late endosome transport GO:0045022 12 5 0,000 1,991E-03 0,02575164 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 1,991E-03 0,02561393 ! depyrimidination GO:0045008 10 5 0,000 1,991E-03 0,02547769 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 1,991E-03 0,02534289 ! regulation of centrosome cycle GO:0046605 7 5 0,000 1,991E-03 0,0252095 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 1,991E-03 0,02507752 ! zinc ion homeostasis GO:0055069 8 5 0,000 1,991E-03 0,0249469 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 1,991E-03 0,02481765 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 1,991E-03 0,02468972 ! forebrain morphogenesis GO:0048853 13 5 0,000 1,991E-03 0,02456311 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 1,991E-03 0,02443778 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 1,991E-03 0,02431373 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 1,991E-03 0,02419094 ! peptidyl-arginine modification GO:0018195 9 5 0,000 1,991E-03 0,02406938 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 1,991E-03 0,02394903 ! positive regulation of organ growth GO:0046622 6 5 0,000 1,991E-03 0,02382988 ! response to arsenic GO:0046685 10 5 0,000 1,991E-03 0,02371191 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 1,991E-03 0,0235951 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 1,991E-03 0,02347944 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 1,991E-03 0,02336491 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 1,991E-03 0,02325148 ! response to cadmium ion GO:0046686 7 5 0,000 1,991E-03 0,02313916 ! bile acid biosynthetic process GO:0006699 6 5 0,000 1,991E-03 0,02302791 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 1,991E-03 0,02291773 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 1,991E-03 0,0228086 ! decidualization GO:0046697 11 5 0,000 1,991E-03 0,0227005 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 1,991E-03 0,02259342 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 1,991E-03 0,02248735 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 1,991E-03 0,02238227 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 1,991E-03 0,02227817 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 1,991E-03 0,02217503 ! base conversion or substitution editing GO:0016553 5 5 0,000 1,991E-03 0,02207284 ! neural tube patterning GO:0021532 7 5 0,000 1,991E-03 0,02197159 ! embryonic cleavage GO:0040016 6 5 0,000 1,991E-03 0,02187126 ! peroxisome fission GO:0016559 5 5 0,000 1,991E-03 0,02177184 ! histone demethylation GO:0016577 10 5 0,000 1,991E-03 0,02167333 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 1,991E-03 0,0215757 ! mitotic recombination GO:0006312 9 5 0,000 1,991E-03 0,02147895 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 1,991E-03 0,02138306 ! metaphase plate congression GO:0051310 7 5 0,000 1,991E-03 0,02128803 ! regulation of sterol transport GO:0032371 7 5 0,000 1,991E-03 0,02119383 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 1,991E-03 0,02110047 ! enteric nervous system development GO:0048484 8 5 0,000 1,991E-03 0,02100792 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 1,991E-03 0,02091618 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 1,991E-03 0,02082524 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 1,991E-03 0,02073509 ! muscle cell proliferation GO:0033002 11 5 0,000 1,991E-03 0,02064571 ! skeletal muscle regeneration GO:0043403 8 5 0,000 1,991E-03 0,02055711 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 1,991E-03 0,02046926 ! plasminogen activation GO:0031639 5 5 0,000 1,991E-03 0,02038215 ! B cell homeostasis GO:0001782 13 5 0,000 1,991E-03 0,02029579 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 1,991E-03 0,02021015 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 1,991E-03 0,02012523 ! metaphase GO:0051323 8 5 0,000 1,991E-03 0,02004103 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 1,991E-03 0,01995752 ! cellular response to nutrient GO:0031670 8 5 0,000 1,991E-03 0,01987471 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 1,991E-03 0,01979259 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 1,991E-03 0,01971113 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 1,991E-03 0,01963035 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 1,991E-03 0,01955023 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 1,991E-03 0,01947075 ! response to redox state GO:0051775 5 5 0,000 1,991E-03 0,01939193 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 1,991E-03 0,01931373 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 1,991E-03 0,01923617 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 1,991E-03 0,01915922 ! regulation of telomerase activity GO:0051972 6 5 0,000 1,991E-03 0,01908289 ! galactolipid metabolic process GO:0019374 7 5 0,000 1,991E-03 0,01900717 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 1,991E-03 0,01893204 ! porphyrin catabolic process GO:0006787 12 5 0,000 1,991E-03 0,0188575 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 1,991E-03 0,01878355 ! striatum development GO:0021756 9 5 0,000 1,991E-03 0,01871018 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 1,991E-03 0,01863738 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 1,991E-03 0,01856514 ! glial cell migration GO:0008347 11 5 0,000 1,991E-03 0,01849346 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 1,991E-03 0,01842233 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 1,991E-03 0,01835175 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 1,991E-03 0,0182817 ! somatic stem cell maintenance GO:0035019 15 5 0,000 1,991E-03 0,01821219 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 1,991E-03 0,0181432 ! negative regulation of lipase activity GO:0060192 8 5 0,000 1,991E-03 0,01807474 ! neuroprotection GO:0043526 6 5 0,000 1,991E-03 0,01800679 ! neural plate development GO:0001840 8 5 0,000 1,991E-03 0,01793935 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 1,991E-03 0,01787241 ! regulation of sensory perception GO:0051931 7 5 0,000 1,991E-03 0,01780597 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 1,991E-03 0,01774002 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 1,991E-03 0,01767456 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 1,991E-03 0,01760958 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 1,991E-03 0,01754508 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 1,991E-03 0,01748104 ! sequestering of calcium ion GO:0051208 7 5 0,000 1,991E-03 0,01741748 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 1,991E-03 0,01735437 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 1,991E-03 0,01729172 ! spindle assembly GO:0051225 6 5 0,000 1,991E-03 0,01722952 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 1,991E-03 0,01716776 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 1,991E-03 0,01710645 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 1,991E-03 0,01704557 ! drug metabolic process GO:0017144 6 5 0,000 1,991E-03 0,01698513 ! stem cell division GO:0017145 11 5 0,000 1,991E-03 0,01692511 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 1,991E-03 0,01686551 ! organ regeneration GO:0031100 7 5 0,000 1,991E-03 0,01680634 ! carnitine metabolic process GO:0009437 7 5 0,000 1,991E-03 0,01674757 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 1,991E-03 0,01668922 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 1,991E-03 0,01663127 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 2,388E-03 0,01988484 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 2,388E-03 0,01981627 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 2,388E-03 0,01974817 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 2,388E-03 0,01968054 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 2,388E-03 0,01961337 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 2,388E-03 0,01954666 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 2,388E-03 0,0194804 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 2,388E-03 0,01941459 ! sleep GO:0030431 13 6 0,000 2,388E-03 0,01934922 ! response to oxygen radical GO:0000305 11 6 0,000 2,388E-03 0,01928429 ! positive regulation of axon extension GO:0045773 11 6 0,000 2,388E-03 0,01921979 ! myoblast cell fate commitment GO:0048625 16 6 0,000 2,388E-03 0,01915572 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 2,388E-03 0,01909208 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 2,388E-03 0,01902887 ! regulation of interferon-beta production GO:0032648 8 6 0,000 2,388E-03 0,01896606 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 2,388E-03 0,01890368 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 2,388E-03 0,0188417 ! forebrain regionalization GO:0021871 8 6 0,000 2,388E-03 0,01878012 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 2,388E-03 0,01871895 ! male meiosis GO:0007140 7 6 0,000 2,388E-03 0,01865817 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 2,388E-03 0,01859779 ! response to zinc ion GO:0010043 9 6 0,000 2,388E-03 0,0185378 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 2,388E-03 0,01847819 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 2,388E-03 0,01841897 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 2,388E-03 0,01836012 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 2,388E-03 0,01830165 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 2,388E-03 0,01824355 ! malate metabolic process GO:0006108 11 6 0,000 2,388E-03 0,01818581 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 2,388E-03 0,01812845 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 2,388E-03 0,01807144 ! protein refolding GO:0042026 15 6 0,000 2,388E-03 0,01801479 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 2,388E-03 0,01795849 ! opsonization GO:0008228 8 6 0,000 2,388E-03 0,01790255 ! mating behavior GO:0007617 7 6 0,000 2,388E-03 0,01784695 ! neuron remodeling GO:0016322 15 6 0,000 2,388E-03 0,01779169 ! erythrocyte maturation GO:0043249 7 6 0,000 2,388E-03 0,01773678 ! embryonic hemopoiesis GO:0035162 14 6 0,000 2,388E-03 0,01768221 ! equilibrioception GO:0050957 14 6 0,000 2,388E-03 0,01762797 ! protein amino acid dealkylation GO:0008214 12 6 0,000 2,388E-03 0,01757406 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 2,388E-03 0,01752048 ! photoreceptor cell development GO:0042461 10 6 0,000 2,388E-03 0,01746723 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 2,388E-03 0,01741429 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 2,388E-03 0,01736168 ! response to interferon-gamma GO:0034341 15 6 0,000 2,388E-03 0,01730939 ! toxin metabolic process GO:0009404 11 6 0,000 2,388E-03 0,01725741 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 2,388E-03 0,01720574 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 2,388E-03 0,01715438 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 2,388E-03 0,01710333 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 2,388E-03 0,01705257 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 2,388E-03 0,01700212 ! cGMP-mediated signaling GO:0019934 13 6 0,000 2,388E-03 0,01695197 ! activation of MAPKKK activity GO:0000185 12 6 0,000 2,388E-03 0,01690211 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 2,388E-03 0,01685254 ! thymic T cell selection GO:0045061 12 6 0,000 2,388E-03 0,01680327 ! protein lipoylation GO:0009249 10 6 0,000 2,388E-03 0,01675428 ! cysteine metabolic process GO:0006534 10 6 0,000 2,388E-03 0,01670557 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 2,388E-03 0,01665715 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 2,388E-03 0,01660901 ! glutamate catabolic process GO:0006538 10 6 0,000 2,388E-03 0,01656115 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 2,388E-03 0,01651356 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 2,388E-03 0,01646624 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 2,388E-03 0,01641919 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 2,388E-03 0,01637241 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 2,388E-03 0,0163259 ! hyperosmotic response GO:0006972 9 6 0,000 2,388E-03 0,01627965 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 2,388E-03 0,01623366 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 2,388E-03 0,01618794 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 2,388E-03 0,01614246 ! urea metabolic process GO:0019627 7 6 0,000 2,388E-03 0,01609725 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 2,388E-03 0,01605228 ! neutrophil activation GO:0042119 8 6 0,000 2,388E-03 0,01600757 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 2,388E-03 0,0159631 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 2,388E-03 0,01591888 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 2,388E-03 0,01587491 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 2,388E-03 0,01583118 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 2,388E-03 0,01578768 ! neuron apoptosis GO:0051402 9 6 0,000 2,388E-03 0,01574443 ! nucleoside salvage GO:0043174 9 6 0,000 2,388E-03 0,01570141 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 2,388E-03 0,01565863 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 2,388E-03 0,01561608 ! T cell mediated immunity GO:0002456 16 6 0,000 2,388E-03 0,01557376 ! negative regulation of platelet activation GO:0010544 9 6 0,000 2,388E-03 0,01553167 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 2,388E-03 0,0154898 ! carnitine transport GO:0015879 10 6 0,000 2,388E-03 0,01544816 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 2,388E-03 0,01540675 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 2,388E-03 0,01536555 ! positive regulation of exocytosis GO:0045921 8 6 0,000 2,388E-03 0,01532458 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 2,388E-03 0,01528382 ! 5S class rRNA transcription GO:0042791 11 6 0,000 2,388E-03 0,01524328 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 2,388E-03 0,01520296 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 2,388E-03 0,01516284 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 2,388E-03 0,01512294 ! sodium ion homeostasis GO:0055078 11 6 0,000 2,388E-03 0,01508325 ! establishment of spindle localization GO:0051293 12 6 0,000 2,388E-03 0,01504376 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 2,388E-03 0,01500448 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 2,388E-03 0,01496541 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 2,388E-03 0,01492654 ! neural nucleus development GO:0048857 14 6 0,000 2,388E-03 0,01488787 ! response to UV-C GO:0010225 11 6 0,000 2,388E-03 0,0148494 ! astrocyte development GO:0014002 15 6 0,000 2,388E-03 0,01481113 ! protein targeting to lysosome GO:0006622 10 6 0,000 2,388E-03 0,01477305 ! purine base biosynthetic process GO:0009113 17 6 0,000 2,388E-03 0,01473517 ! interaction with symbiont GO:0051702 13 6 0,000 2,388E-03 0,01469749 ! regulation of dendrite development GO:0050773 16 6 0,000 2,388E-03 0,01465999 ! skeletal muscle contraction GO:0003009 6 6 0,000 2,388E-03 0,01462269 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 2,388E-03 0,01458558 ! response to copper ion GO:0046688 10 6 0,000 2,388E-03 0,01454865 ! response to exogenous dsRNA GO:0043330 10 6 0,000 2,388E-03 0,01451191 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 2,388E-03 0,01447536 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 2,388E-03 0,01443899 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 2,388E-03 0,0144028 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 2,388E-03 0,01436679 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 2,388E-03 0,01433097 ! regulation of dopamine secretion GO:0014059 14 6 0,000 2,388E-03 0,01429532 ! nucleoside catabolic process GO:0009164 7 6 0,000 2,388E-03 0,01425984 ! hair follicle maturation GO:0048820 7 6 0,000 2,388E-03 0,01422455 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 2,388E-03 0,01418943 ! Schwann cell development GO:0014044 15 6 0,000 2,388E-03 0,01415448 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 2,388E-03 0,0141197 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 2,388E-03 0,01408509 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 2,388E-03 0,01405065 ! subpallium development GO:0021544 10 6 0,000 2,388E-03 0,01401638 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 2,388E-03 0,01398228 ! histone ubiquitination GO:0016574 8 6 0,000 2,388E-03 0,01394834 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 2,388E-03 0,01391457 ! maintenance of organ identity GO:0048496 9 6 0,000 2,388E-03 0,01388096 ! G2 phase GO:0051319 16 6 0,000 2,388E-03 0,01384751 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 2,388E-03 0,01381422 ! establishment of planar polarity GO:0001736 7 6 0,000 2,388E-03 0,0137811 ! regulation of mast cell activation GO:0033003 12 6 0,000 2,388E-03 0,01374813 ! membrane to membrane docking GO:0022614 14 6 0,000 2,388E-03 0,01371532 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 2,388E-03 0,01368266 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 2,388E-03 0,01365016 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 2,388E-03 0,01361781 ! receptor internalization GO:0031623 10 6 0,000 2,388E-03 0,01358562 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 2,388E-03 0,01355358 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 2,388E-03 0,01352169 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 2,388E-03 0,01348995 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 2,388E-03 0,01345835 ! protein deubiquitination GO:0016579 14 6 0,000 2,388E-03 0,01342691 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 2,388E-03 0,01339561 ! protein destabilization GO:0031648 9 6 0,000 2,388E-03 0,01336446 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 2,388E-03 0,01333345 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 2,388E-03 0,01330259 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 2,388E-03 0,01327186 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 2,388E-03 0,01324128 ! progesterone metabolic process GO:0042448 10 6 0,000 2,388E-03 0,01321084 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 2,388E-03 0,01318054 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 2,388E-03 0,01315038 ! negative regulation of axon extension GO:0030517 21 6 0,000 2,388E-03 0,01312036 ! removal of superoxide radicals GO:0019430 11 6 0,000 2,388E-03 0,01309047 ! triglyceride catabolic process GO:0019433 10 6 0,000 2,388E-03 0,01306072 ! determination of adult lifespan GO:0008340 15 6 0,000 2,388E-03 0,01303111 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 2,388E-03 0,01300162 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 2,388E-03 0,01297227 ! cerebellar cortex formation GO:0021697 8 6 0,000 2,388E-03 0,01294306 ! catecholamine transport GO:0051937 9 6 0,000 2,388E-03 0,01291397 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 2,388E-03 0,01288502 ! sensory cilium assembly GO:0035058 10 6 0,000 2,388E-03 0,01285619 ! organ or tissue specific immune response GO:0002251 7 6 0,000 2,388E-03 0,01282749 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 2,388E-03 0,01279892 ! maternal placenta development GO:0001893 12 6 0,000 2,388E-03 0,01277048 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 2,388E-03 0,01274217 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 2,388E-03 0,01271398 ! negative regulation of B cell activation GO:0050869 13 6 0,000 2,388E-03 0,01268591 ! protein amino acid prenylation GO:0018346 16 6 0,000 2,388E-03 0,01265797 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 2,388E-03 0,01263015 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 2,388E-03 0,01260245 ! positive regulation of coagulation GO:0050820 12 6 0,000 2,388E-03 0,01257487 ! tRNA transcription GO:0009304 14 7 0,000 2,786E-03 0,01463598 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 2,786E-03 0,01460409 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 2,786E-03 0,01457235 ! behavioral response to cocaine GO:0048148 14 7 0,000 2,786E-03 0,01454074 ! regulation of helicase activity GO:0051095 15 7 0,000 2,786E-03 0,01450926 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 2,786E-03 0,01447793 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 2,786E-03 0,01444672 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 2,786E-03 0,01441565 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 2,786E-03 0,01438472 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 2,786E-03 0,01435392 ! prostate gland development GO:0030850 13 7 0,000 2,786E-03 0,01432325 ! nucleotide-sugar transport GO:0015780 12 7 0,000 2,786E-03 0,01429271 ! synaptonemal complex assembly GO:0007130 10 7 0,000 2,786E-03 0,0142623 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 2,786E-03 0,01423202 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 2,786E-03 0,01420186 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 2,786E-03 0,01417184 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 2,786E-03 0,01414194 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 2,786E-03 0,01411217 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 2,786E-03 0,01408252 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 2,786E-03 0,014053 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 2,786E-03 0,0140236 ! SMAD protein complex assembly GO:0007183 12 7 0,000 2,786E-03 0,01399432 ! glycolipid transport GO:0046836 10 7 0,000 2,786E-03 0,01396517 ! protein amino acid sulfation GO:0006477 10 7 0,000 2,786E-03 0,01393613 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 2,786E-03 0,01390722 ! neuron adhesion GO:0007158 12 7 0,000 2,786E-03 0,01387843 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 2,786E-03 0,01384975 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 2,786E-03 0,01382119 ! actin-myosin filament sliding GO:0033275 11 7 0,000 2,786E-03 0,01379276 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 2,786E-03 0,01376443 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 2,786E-03 0,01373623 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 2,786E-03 0,01370814 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 2,786E-03 0,01368016 ! mRNA stabilization GO:0048255 18 7 0,000 2,786E-03 0,0136523 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 2,786E-03 0,01362455 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 2,786E-03 0,01359692 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 2,786E-03 0,01356939 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 2,786E-03 0,01354198 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 2,786E-03 0,01351468 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 2,786E-03 0,01348748 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 2,786E-03 0,0134604 ! lipoprotein transport GO:0042953 14 7 0,000 2,786E-03 0,01343343 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 2,786E-03 0,01340656 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 2,786E-03 0,0133798 ! rhythmic behavior GO:0007622 15 7 0,000 2,786E-03 0,01335315 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 2,786E-03 0,0133266 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 2,786E-03 0,01330016 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 2,786E-03 0,01327382 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 2,786E-03 0,01324759 ! regulation of odontogenesis GO:0042481 13 7 0,000 2,786E-03 0,01322146 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 2,786E-03 0,01319543 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 2,786E-03 0,01316951 ! mechanosensory behavior GO:0007638 14 7 0,000 2,786E-03 0,01314369 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 2,786E-03 0,01311796 ! positive regulation of isotype switching GO:0045830 15 7 0,000 2,786E-03 0,01309234 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 2,786E-03 0,01306682 ! protein-cofactor linkage GO:0018065 13 7 0,000 2,786E-03 0,0130414 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 2,786E-03 0,01301608 ! spinal cord patterning GO:0021511 13 7 0,000 2,786E-03 0,01299085 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 2,786E-03 0,01296572 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 2,786E-03 0,01294069 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 2,786E-03 0,01291576 ! adrenal gland development GO:0030325 17 7 0,000 2,786E-03 0,01289092 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 2,786E-03 0,01286618 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 2,786E-03 0,01284153 ! ovulation GO:0030728 9 7 0,000 2,786E-03 0,01281698 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 2,786E-03 0,01279252 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 2,786E-03 0,01276815 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 2,786E-03 0,01274388 ! microtubule nucleation GO:0007020 20 7 0,000 2,786E-03 0,0127197 ! proline biosynthetic process GO:0006561 10 7 0,000 2,786E-03 0,0126956 ! thyroid hormone generation GO:0006590 13 7 0,000 2,786E-03 0,01267161 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 2,786E-03 0,0126477 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 2,786E-03 0,01262388 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 2,786E-03 0,01260015 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 2,786E-03 0,01257651 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 2,786E-03 0,01255296 ! galactose metabolic process GO:0006012 13 7 0,000 2,786E-03 0,01252949 ! vesicle fusion GO:0006906 17 7 0,000 2,786E-03 0,01250612 ! response to dietary excess GO:0002021 8 7 0,000 2,786E-03 0,01248283 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 2,786E-03 0,01245963 ! intracellular pH reduction GO:0051452 11 7 0,000 2,786E-03 0,01243651 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 2,786E-03 0,01241348 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 2,786E-03 0,01239053 ! organ growth GO:0035265 15 7 0,000 2,786E-03 0,01236767 ! purine salvage GO:0043101 10 7 0,000 2,786E-03 0,0123449 ! nucleoside transport GO:0015858 8 7 0,000 2,786E-03 0,0123222 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 2,786E-03 0,0122996 ! parturition GO:0007567 14 7 0,000 2,786E-03 0,01227707 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 2,786E-03 0,01225462 ! rRNA modification GO:0000154 14 7 0,000 2,786E-03 0,01223226 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 2,786E-03 0,01220998 ! spindle checkpoint GO:0031577 15 7 0,000 2,786E-03 0,01218778 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 2,786E-03 0,01216566 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 2,786E-03 0,01214362 ! macrophage differentiation GO:0030225 11 7 0,000 2,786E-03 0,01212166 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 2,786E-03 0,01209978 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 2,786E-03 0,01207798 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 2,786E-03 0,01205626 ! hyaluronan metabolic process GO:0030212 8 7 0,000 2,786E-03 0,01203461 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 2,786E-03 0,01201305 ! anterograde axon cargo transport GO:0008089 18 7 0,000 2,786E-03 0,01199156 ! fibrinolysis GO:0042730 10 7 0,000 2,786E-03 0,01197014 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 2,786E-03 0,0119488 ! eating behavior GO:0042755 7 7 0,000 2,786E-03 0,01192754 ! B cell lineage commitment GO:0002326 21 7 0,000 2,786E-03 0,01190636 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 2,786E-03 0,01188525 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 2,786E-03 0,01186421 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 2,786E-03 0,01184325 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 2,786E-03 0,01182236 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 2,786E-03 0,01180155 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 2,786E-03 0,01178081 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 2,786E-03 0,01176014 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 2,786E-03 0,01173954 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 2,786E-03 0,01171902 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 2,786E-03 0,01169857 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 2,786E-03 0,01167819 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 2,786E-03 0,01165788 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 2,786E-03 0,01163764 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 2,786E-03 0,01161747 ! regulation of meiosis GO:0040020 12 7 0,000 2,786E-03 0,01159737 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 2,786E-03 0,01157734 ! T cell lineage commitment GO:0002360 16 7 0,000 2,786E-03 0,01155738 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 2,786E-03 0,01153749 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 2,786E-03 0,01151766 ! oxygen homeostasis GO:0032364 12 7 0,000 2,786E-03 0,01149791 ! transcription termination GO:0006353 13 7 0,000 2,786E-03 0,01147822 ! response to tumor cell GO:0002347 13 7 0,000 2,786E-03 0,0114586 ! regulation of respiratory burst GO:0060263 11 7 0,000 2,786E-03 0,01143904 ! coenzyme A metabolic process GO:0015936 12 7 0,000 2,786E-03 0,01141956 ! anaphase GO:0051322 17 7 0,000 2,786E-03 0,01140013 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 2,786E-03 0,01138078 ! axonal fasciculation GO:0007413 18 7 0,000 2,786E-03 0,01136149 ! negative regulation of nuclear division GO:0051784 14 7 0,000 2,786E-03 0,01134227 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 2,786E-03 0,01132311 ! peptidyl-threonine modification GO:0018210 25 7 0,000 2,786E-03 0,01130401 ! diuresis GO:0030146 12 7 0,000 2,786E-03 0,01128498 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 2,786E-03 0,01126602 ! thiamin metabolic process GO:0006772 7 7 0,000 2,786E-03 0,01124711 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 2,786E-03 0,01122827 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 2,786E-03 0,0112095 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 2,786E-03 0,01119078 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 2,786E-03 0,01117213 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 2,786E-03 0,01115354 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 2,786E-03 0,01113502 ! melanin biosynthetic process GO:0042438 8 7 0,000 2,786E-03 0,01111655 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 2,786E-03 0,01109814 ! dopamine biosynthetic process GO:0042416 18 7 0,000 2,786E-03 0,0110798 ! glycolipid catabolic process GO:0019377 15 7 0,000 2,786E-03 0,01106152 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 2,786E-03 0,01104329 ! lymph node development GO:0048535 10 7 0,000 2,786E-03 0,01102513 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 2,786E-03 0,01100703 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 2,786E-03 0,01098898 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 2,786E-03 0,010971 ! endosome to lysosome transport GO:0008333 11 7 0,000 2,786E-03 0,01095307 ! protein modification by small protein removal GO:0070646 16 7 0,000 2,786E-03 0,0109352 ! adult feeding behavior GO:0008343 9 7 0,000 2,786E-03 0,01091739 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 2,786E-03 0,01089964 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 2,786E-03 0,01088195 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 2,786E-03 0,01086431 ! muscle adaptation GO:0043500 14 7 0,000 2,786E-03 0,01084673 ! embryonic heart tube development GO:0035050 10 7 0,000 2,786E-03 0,01082921 ! retina homeostasis GO:0001895 12 7 0,000 2,786E-03 0,01081174 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 2,786E-03 0,01079433 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 2,786E-03 0,01077698 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 2,786E-03 0,01075968 ! protein prenylation GO:0018342 18 7 0,000 2,786E-03 0,01074243 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 2,786E-03 0,01072525 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 2,786E-03 0,01070811 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 2,786E-03 0,01069104 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 3,183E-03 0,01219664 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 3,183E-03 0,01217725 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 3,183E-03 0,01215792 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 3,183E-03 0,01213866 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 3,183E-03 0,01211945 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 3,183E-03 0,0121003 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 3,183E-03 0,01208122 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 3,183E-03 0,01206219 ! neutral lipid catabolic process GO:0046461 13 8 0,000 3,183E-03 0,01204323 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 3,183E-03 0,01202432 ! meiotic prophase I GO:0007128 13 8 0,000 3,183E-03 0,01200547 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 3,183E-03 0,01198669 ! oligopeptide transport GO:0006857 15 8 0,000 3,183E-03 0,01196796 ! UTP metabolic process GO:0046051 8 8 0,000 3,183E-03 0,01194929 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 3,183E-03 0,01193067 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 3,183E-03 0,01191212 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 3,183E-03 0,01189362 ! macrophage chemotaxis GO:0048246 12 8 0,000 3,183E-03 0,01187518 ! succinate metabolic process GO:0006105 14 8 0,000 3,183E-03 0,0118568 ! membrane hyperpolarization GO:0060081 10 8 0,000 3,183E-03 0,01183847 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 3,183E-03 0,0118202 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 3,183E-03 0,01180199 ! T-helper 1 type immune response GO:0042088 12 8 0,000 3,183E-03 0,01178383 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 3,183E-03 0,01176573 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 3,183E-03 0,01174769 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 3,183E-03 0,0117297 ! ganglioside metabolic process GO:0001573 19 8 0,000 3,183E-03 0,01171176 ! reflex GO:0060004 16 8 0,000 3,183E-03 0,01169388 ! negative regulation of endocytosis GO:0045806 11 8 0,000 3,183E-03 0,01167605 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 3,183E-03 0,01165828 ! endothelial cell differentiation GO:0045446 17 8 0,000 3,183E-03 0,01164057 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 3,183E-03 0,0116229 ! glycerolipid catabolic process GO:0046503 13 8 0,000 3,183E-03 0,01160529 ! hemoglobin metabolic process GO:0020027 13 8 0,000 3,183E-03 0,01158773 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 3,183E-03 0,01157023 ! pigment granule organization GO:0048753 16 8 0,000 3,183E-03 0,01155278 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 3,183E-03 0,01153538 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 3,183E-03 0,01151803 ! astrocyte differentiation GO:0048708 18 8 0,000 3,183E-03 0,01150074 ! histidine metabolic process GO:0006547 16 8 0,000 3,183E-03 0,0114835 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 3,183E-03 0,01146631 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 3,183E-03 0,01144917 ! glycine catabolic process GO:0006546 13 8 0,000 3,183E-03 0,01143208 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 3,183E-03 0,01141504 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 3,183E-03 0,01139805 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 3,183E-03 0,01138112 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 3,183E-03 0,01136423 ! regulation of pigmentation during development GO:0048070 24 8 0,000 3,183E-03 0,0113474 ! melanin metabolic process GO:0006582 15 8 0,000 3,183E-03 0,01133061 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 3,183E-03 0,01131387 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 3,183E-03 0,01129719 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 3,183E-03 0,01128055 ! macrophage activation GO:0042116 12 8 0,000 3,183E-03 0,01126396 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 3,183E-03 0,01124742 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 3,183E-03 0,01123093 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 3,183E-03 0,01121448 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 3,183E-03 0,01119809 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 3,183E-03 0,01118174 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 3,183E-03 0,01116544 ! regulation of vascular permeability GO:0043114 12 8 0,000 3,183E-03 0,01114919 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 3,183E-03 0,01113298 ! osteoblast development GO:0002076 16 8 0,000 3,183E-03 0,01111682 ! positive regulation of vasodilation GO:0045909 13 8 0,000 3,183E-03 0,01110071 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 3,183E-03 0,01108465 ! negative regulation of translational initiation GO:0045947 10 8 0,000 3,183E-03 0,01106863 ! Schwann cell differentiation GO:0014037 19 8 0,000 3,183E-03 0,01105266 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 3,183E-03 0,01103673 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 3,183E-03 0,01102085 ! response to UV-B GO:0010224 16 8 0,000 3,183E-03 0,01100502 ! protein targeting to vacuole GO:0006623 12 8 0,000 3,183E-03 0,01098923 ! protein retention in ER lumen GO:0006621 14 8 0,000 3,183E-03 0,01097348 ! intermediate filament organization GO:0045109 12 8 0,000 3,183E-03 0,01095779 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 3,183E-03 0,01094213 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 3,183E-03 0,01092652 ! cellular extravasation GO:0045123 12 8 0,000 3,183E-03 0,01091096 ! cardiac muscle cell development GO:0055013 13 8 0,000 3,183E-03 0,01089544 ! regulation of circadian rhythm GO:0042752 16 8 0,000 3,183E-03 0,01087996 ! response to antibiotic GO:0046677 11 8 0,000 3,183E-03 0,01086453 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 3,183E-03 0,01084914 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 3,183E-03 0,01083379 ! DNA topological change GO:0006265 12 8 0,000 3,183E-03 0,01081849 ! response to tropane GO:0014073 15 8 0,000 3,183E-03 0,01080323 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 3,183E-03 0,01078802 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 3,183E-03 0,01077284 ! melanosome transport GO:0032402 13 8 0,000 3,183E-03 0,01075771 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 0,000 3,183E-03 0,01074263 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 3,183E-03 0,01072758 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 3,183E-03 0,01071258 ! mast cell activation GO:0045576 14 8 0,000 3,183E-03 0,01069761 ! multicellular organismal aging GO:0010259 18 8 0,000 3,183E-03 0,01068269 ! dendrite morphogenesis GO:0048813 13 8 0,000 3,183E-03 0,01066782 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 3,183E-03 0,01065298 ! nucleosome disassembly GO:0006337 14 8 0,000 3,183E-03 0,01063818 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 3,183E-03 0,01062343 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 3,183E-03 0,01060871 ! leukocyte activation during immune response GO:0002366 13 8 0,000 3,183E-03 0,01059404 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 3,183E-03 0,01057941 ! establishment of chromosome localization GO:0051303 12 8 0,000 3,183E-03 0,01056482 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 3,183E-03 0,01055026 ! intracellular lipid transport GO:0032365 13 8 0,000 3,183E-03 0,01053575 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 3,183E-03 0,01052128 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 3,183E-03 0,01050685 ! regulation of macrophage activation GO:0043030 15 8 0,000 3,183E-03 0,01049245 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 3,183E-03 0,0104781 ! positive regulation of epidermis development GO:0045684 13 8 0,000 3,183E-03 0,01046379 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 3,183E-03 0,01044951 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 3,183E-03 0,01043528 ! hormone catabolic process GO:0042447 17 8 0,000 3,183E-03 0,01042108 ! positive regulation of glucose import GO:0046326 8 8 0,000 3,183E-03 0,01040692 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 3,183E-03 0,0103928 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 3,183E-03 0,01037872 ! ATP catabolic process GO:0006200 11 8 0,000 3,183E-03 0,01036467 ! blastocyst growth GO:0001832 19 8 0,000 3,183E-03 0,01035066 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 3,183E-03 0,0103367 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 3,183E-03 0,01032277 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 3,183E-03 0,01030887 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 3,183E-03 0,01029502 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 3,183E-03 0,0102812 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 3,183E-03 0,01026742 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 3,183E-03 0,01025367 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 3,183E-03 0,01023996 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 3,183E-03 0,01022629 ! amino sugar catabolic process GO:0046348 10 8 0,000 3,183E-03 0,01021266 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 3,183E-03 0,01019906 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 3,183E-03 0,01018549 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 3,183E-03 0,01017197 ! behavioral response to nicotine GO:0035095 12 8 0,000 3,183E-03 0,01015848 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 3,183E-03 0,01014502 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 3,183E-03 0,0101316 ! NAD biosynthetic process GO:0009435 13 8 0,000 3,183E-03 0,01011822 ! regulation of developmental growth GO:0048638 15 9 0,000 3,581E-03 0,0113659 ! axon extension GO:0048675 15 9 0,000 3,581E-03 0,01135093 ! autophagic vacuole formation GO:0000045 15 9 0,000 3,581E-03 0,01133599 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 3,581E-03 0,0113211 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 3,581E-03 0,01130624 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 3,581E-03 0,01129142 ! pentose-phosphate shunt GO:0006098 16 9 0,000 3,581E-03 0,01127664 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 3,581E-03 0,0112619 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 3,581E-03 0,0112472 ! cell proliferation in forebrain GO:0021846 15 9 0,000 3,581E-03 0,01123254 ! phosphate transport GO:0006817 19 9 0,000 3,581E-03 0,01121791 ! reproductive behavior GO:0019098 19 9 0,000 3,581E-03 0,01120332 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 3,581E-03 0,01118877 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 3,581E-03 0,01117426 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 3,581E-03 0,01115979 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 3,581E-03 0,01114535 ! GTP metabolic process GO:0046039 9 9 0,000 3,581E-03 0,01113095 ! RNA methylation GO:0001510 15 9 0,000 3,581E-03 0,01111659 ! elastic fiber assembly GO:0048251 15 9 0,000 3,581E-03 0,01110226 ! induction of positive chemotaxis GO:0050930 15 9 0,000 3,581E-03 0,01108797 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 3,581E-03 0,01107372 ! artery development GO:0060840 24 9 0,000 3,581E-03 0,01105951 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 3,581E-03 0,01104533 ! regulation of glycolysis GO:0006110 21 9 0,000 3,581E-03 0,01103118 ! cerebral cortex cell migration GO:0021795 15 9 0,000 3,581E-03 0,01101708 ! keratinocyte proliferation GO:0043616 14 9 0,000 3,581E-03 0,01100301 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 3,581E-03 0,01098897 ! chemosensory behavior GO:0007635 20 9 0,000 3,581E-03 0,01097497 ! microtubule bundle formation GO:0001578 21 9 0,000 3,581E-03 0,01096101 ! middle ear morphogenesis GO:0042474 14 9 0,000 3,581E-03 0,01094708 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 3,581E-03 0,01093319 ! leukocyte degranulation GO:0043299 16 9 0,000 3,581E-03 0,01091933 ! bile acid and bile salt transport GO:0015721 13 9 0,000 3,581E-03 0,01090551 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 3,581E-03 0,01089173 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 3,581E-03 0,01087797 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 3,581E-03 0,01086426 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 3,581E-03 0,01085057 ! protein targeting to ER GO:0045047 22 9 0,000 3,581E-03 0,01083692 ! ceramide biosynthetic process GO:0046513 19 9 0,000 3,581E-03 0,01082331 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 3,581E-03 0,01080973 ! T cell selection GO:0045058 23 9 0,000 3,581E-03 0,01079618 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 3,581E-03 0,01078267 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 3,581E-03 0,01076919 ! phosphagen metabolic process GO:0006599 12 9 0,000 3,581E-03 0,01075575 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 3,581E-03 0,01074234 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 3,581E-03 0,01072896 ! regulation of type I interferon production GO:0032479 12 9 0,000 3,581E-03 0,01071562 ! mannose metabolic process GO:0006013 13 9 0,000 3,581E-03 0,0107023 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 3,581E-03 0,01068903 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 3,581E-03 0,01067578 ! Rac protein signal transduction GO:0016601 17 9 0,000 3,581E-03 0,01066257 ! receptor clustering GO:0043113 18 9 0,000 3,581E-03 0,01064939 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 3,581E-03 0,01063624 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 3,581E-03 0,01062313 ! ruffle organization GO:0031529 15 9 0,000 3,581E-03 0,01061004 ! retinol metabolic process GO:0042572 18 9 0,000 3,581E-03 0,01059699 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 3,581E-03 0,01058397 ! behavioral fear response GO:0001662 22 9 0,000 3,581E-03 0,01057099 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 3,581E-03 0,01055803 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 3,581E-03 0,01054511 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 3,581E-03 0,01053222 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 3,581E-03 0,01051936 ! protein heterooligomerization GO:0051291 16 9 0,000 3,581E-03 0,01050653 ! oligodendrocyte development GO:0014003 10 9 0,000 3,581E-03 0,01049373 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 3,581E-03 0,01048097 ! segment specification GO:0007379 13 9 0,000 3,581E-03 0,01046823 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 3,581E-03 0,01045553 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 3,581E-03 0,01044285 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 3,581E-03 0,01043021 ! response to amine stimulus GO:0014075 13 9 0,000 3,581E-03 0,0104176 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 3,581E-03 0,01040502 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 3,581E-03 0,01039247 ! erythrocyte development GO:0048821 15 9 0,000 3,581E-03 0,01037995 ! gas homeostasis GO:0033483 16 9 0,000 3,581E-03 0,01036746 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 3,581E-03 0,01035499 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 3,581E-03 0,01034256 ! renal water homeostasis GO:0003091 14 9 0,000 3,581E-03 0,01033016 ! postreplication repair GO:0006301 22 9 0,000 3,581E-03 0,01031779 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 3,581E-03 0,01030545 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 3,581E-03 0,01029314 ! icosanoid secretion GO:0032309 15 9 0,000 3,581E-03 0,01028085 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 3,581E-03 0,0102686 ! cerebellum morphogenesis GO:0021587 14 9 0,000 3,581E-03 0,01025638 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 3,581E-03 0,01024418 ! regulation of cell division GO:0051302 15 9 0,000 3,581E-03 0,01023201 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 3,581E-03 0,01021988 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 3,581E-03 0,01020777 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 3,581E-03 0,01019569 ! sterol catabolic process GO:0016127 11 9 0,000 3,581E-03 0,01018363 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 3,581E-03 0,01017161 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 3,581E-03 0,01015962 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 3,581E-03 0,01014765 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 3,581E-03 0,01013571 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 3,581E-03 0,0101238 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 3,581E-03 0,01011192 ! musculoskeletal movement GO:0050881 14 9 0,000 3,581E-03 0,01010006 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 3,581E-03 0,01008824 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 3,581E-03 0,01007644 ! regulation of synaptogenesis GO:0051963 15 9 0,000 3,581E-03 0,01006467 ! purine base metabolic process GO:0006144 21 9 0,000 3,581E-03 0,01005292 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 3,581E-03 0,01004121 ! pigment granule transport GO:0051904 17 9 0,000 3,581E-03 0,01002952 ! regulation of fibrinolysis GO:0051917 16 9 0,000 3,581E-03 0,01001785 ! regulation of telomere maintenance GO:0032204 14 9 0,000 3,581E-03 0,01000622 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 3,581E-03 9,995E-03 ! regulation of muscle adaptation GO:0043502 14 9 0,000 3,581E-03 9,983E-03 ! regulation of amino acid transport GO:0051955 11 9 0,000 3,581E-03 9,971E-03 ! mitochondrion localization GO:0051646 15 9 0,000 3,581E-03 9,96E-03 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 3,978E-03 0,01105181 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 3,978E-03 0,01103906 ! negative regulation of blood pressure GO:0045776 26 10 0,000 3,978E-03 0,01102635 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 3,978E-03 0,01101366 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 3,978E-03 0,011001 ! synapsis GO:0007129 13 10 0,000 3,978E-03 0,01098837 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 3,978E-03 0,01097577 ! N-glycan processing GO:0006491 20 10 0,000 3,978E-03 0,01096319 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 3,978E-03 0,01095065 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 3,978E-03 0,01093814 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 3,978E-03 0,01092565 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 3,978E-03 0,01091319 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 3,978E-03 0,01090076 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 3,978E-03 0,01088836 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 3,978E-03 0,01087599 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 3,978E-03 0,01086364 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 3,978E-03 0,01085133 ! androgen metabolic process GO:0008209 17 10 0,000 3,978E-03 0,01083904 ! phospholipid efflux GO:0033700 16 10 0,000 3,978E-03 0,01082678 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 3,978E-03 0,01081454 ! positive regulation of heart contraction GO:0045823 16 10 0,000 3,978E-03 0,01080234 ! lung alveolus development GO:0048286 26 10 0,000 3,978E-03 0,01079016 ! pathogenesis GO:0009405 13 10 0,000 3,978E-03 0,01077801 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 3,978E-03 0,01076588 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 3,978E-03 0,01075379 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 3,978E-03 0,01074172 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 3,978E-03 0,01072967 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 3,978E-03 0,01071766 ! endoderm development GO:0007492 16 10 0,000 3,978E-03 0,01070567 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 3,978E-03 0,01069371 ! arginine catabolic process GO:0006527 13 10 0,000 3,978E-03 0,01068177 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 3,978E-03 0,01066987 ! proline metabolic process GO:0006560 13 10 0,000 3,978E-03 0,01065798 ! glucan biosynthetic process GO:0009250 14 10 0,000 3,978E-03 0,01064613 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 3,978E-03 0,0106343 ! polyamine biosynthetic process GO:0006596 12 10 0,000 3,978E-03 0,0106225 ! V(D)J recombination GO:0033151 28 10 0,000 3,978E-03 0,01061072 ! reverse cholesterol transport GO:0043691 16 10 0,000 3,978E-03 0,01059897 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 3,978E-03 0,01058724 GO:0021952|central nervous system projection neuron axonogenesis, ! B cell proliferation GO:0042100 18 10 0,000 3,978E-03 0,01057555 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 3,978E-03 0,01056387 ! regulation of sodium ion transport GO:0002028 21 10 0,000 3,978E-03 0,01055223 ! multicellular organism growth GO:0035264 18 10 0,000 3,978E-03 0,0105406 ! phagocytosis, engulfment GO:0006911 28 10 0,000 3,978E-03 0,01052901 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 3,978E-03 0,01051744 ! epithelial cell development GO:0002064 20 10 0,000 3,978E-03 0,01050589 ! lens development in camera-type eye GO:0002088 16 10 0,000 3,978E-03 0,01049437 ! retinoic acid metabolic process GO:0042573 14 10 0,000 3,978E-03 0,01048288 ! macroautophagy GO:0016236 17 10 0,000 3,978E-03 0,01047141 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 3,978E-03 0,01045997 ! positive regulation of translational initiation GO:0045948 11 10 0,000 3,978E-03 0,01044855 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 3,978E-03 0,01043715 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 3,978E-03 0,01042578 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 3,978E-03 0,01041444 ! copper ion homeostasis GO:0055070 13 10 0,000 3,978E-03 0,01040312 ! regulation of bone resorption GO:0045124 25 10 0,000 3,978E-03 0,01039182 ! regulation of gliogenesis GO:0014013 23 10 0,000 3,978E-03 0,01038055 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 3,978E-03 0,01036931 ! alpha-beta T cell activation GO:0046631 23 10 0,000 3,978E-03 0,01035808 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 3,978E-03 0,01034689 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 3,978E-03 0,01033571 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 3,978E-03 0,01032456 ! blastoderm segmentation GO:0007350 18 10 0,000 3,978E-03 0,01031344 ! response to dsRNA GO:0043331 20 10 0,000 3,978E-03 0,01030233 ! DNA ligation GO:0006266 19 10 0,000 3,978E-03 0,01029126 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 3,978E-03 0,0102802 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 3,978E-03 0,01026917 ! melanosome localization GO:0032400 16 10 0,000 3,978E-03 0,01025817 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 3,978E-03 0,01024718 ! regulation of B cell differentiation GO:0045577 19 10 0,000 3,978E-03 0,01023622 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 3,978E-03 0,01022529 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 3,978E-03 0,01021437 ! mRNA cleavage GO:0006379 17 10 0,000 3,978E-03 0,01020349 ! protein sumoylation GO:0016925 15 10 0,000 3,978E-03 0,01019262 ! hindbrain morphogenesis GO:0021575 19 10 0,000 3,978E-03 0,01018178 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 3,978E-03 0,01017096 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 3,978E-03 0,01016016 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 3,978E-03 0,01014938 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 3,978E-03 0,01013863 ! salivary gland development GO:0007431 27 10 0,000 3,978E-03 0,0101279 ! prophase GO:0051324 15 10 0,000 3,978E-03 0,0101172 ! negative regulation of neurological system process GO:0031645 19 10 0,000 3,978E-03 0,01010651 ! apical protein localization GO:0045176 15 10 0,000 3,978E-03 0,01009585 ! ubiquinone metabolic process GO:0006743 15 10 0,000 3,978E-03 0,01008522 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 3,978E-03 0,0100746 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 3,978E-03 0,01006401 ! midbrain development GO:0030901 13 10 0,000 3,978E-03 0,01005343 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 3,978E-03 0,01004288 ! methionine biosynthetic process GO:0009086 19 10 0,000 3,978E-03 0,01003236 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 3,978E-03 0,01002185 ! quaternary ammonium group transport GO:0015697 21 10 0,000 3,978E-03 0,01001137 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 3,978E-03 0,01000091 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 3,978E-03 9,99E-03 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 3,978E-03 9,98E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 3,978E-03 9,97E-03 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 3,978E-03 9,959E-03 ! oocyte development GO:0048599 17 10 0,000 3,978E-03 9,949E-03 ! establishment of pigment granule localization GO:0051905 18 10 0,000 3,978E-03 9,939E-03 ! blastocyst formation GO:0001825 17 10 0,000 3,978E-03 9,928E-03 ! cerebellar cortex development GO:0021695 15 10 0,000 3,978E-03 9,918E-03 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 3,978E-03 9,908E-03 ! activation of innate immune response GO:0002218 12 10 0,000 3,978E-03 9,897E-03 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 3,978E-03 9,887E-03 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 3,978E-03 9,877E-03 ! response to nicotine GO:0035094 20 10 0,000 3,978E-03 9,867E-03 ! establishment of cell polarity GO:0030010 16 10 0,000 3,978E-03 9,857E-03 ! negative regulation of immune effector process GO:0002698 20 10 0,000 3,978E-03 9,847E-03 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 3,978E-03 9,836E-03 ! localization within membrane GO:0051668 20 10 0,000 3,978E-03 9,826E-03 ! negative regulation of muscle development GO:0048635 20 11 0,000 4,375E-03 0,01079593 ! respiratory burst GO:0045730 17 11 0,000 4,375E-03 0,01078487 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 4,375E-03 0,01077383 ! neuron fate specification GO:0048665 17 11 0,000 4,375E-03 0,01076282 ! telencephalon cell migration GO:0022029 20 11 0,000 4,375E-03 0,01075182 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 4,375E-03 0,01074085 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 4,375E-03 0,0107299 ! thyroid gland development GO:0030878 26 11 0,000 4,375E-03 0,01071898 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 4,375E-03 0,01070807 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 4,375E-03 0,01069719 ! Golgi vesicle budding GO:0048194 22 11 0,000 4,375E-03 0,01068633 ! response to pain GO:0048265 24 11 0,000 4,375E-03 0,01067549 ! detection of mechanical stimulus GO:0050982 22 11 0,000 4,375E-03 0,01066467 ! T cell proliferation GO:0042098 26 11 0,000 4,375E-03 0,01065388 ! blood vessel remodeling GO:0001974 29 11 0,000 4,375E-03 0,01064311 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 4,375E-03 0,01063236 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 4,375E-03 0,01062163 ! bone resorption GO:0045453 16 11 0,000 4,375E-03 0,01061092 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 4,375E-03 0,01060024 ! ventral spinal cord development GO:0021517 21 11 0,000 4,375E-03 0,01058957 ! negative regulation of proteolysis GO:0045861 25 11 0,000 4,375E-03 0,01057893 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 4,375E-03 0,01056831 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 4,375E-03 0,01055771 ! melanocyte differentiation GO:0030318 21 11 0,000 4,375E-03 0,01054713 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 4,375E-03 0,01053657 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 4,375E-03 0,01052603 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 4,375E-03 0,01051552 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 4,375E-03 0,01050502 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 4,375E-03 0,01049455 ! lipid digestion GO:0044241 18 11 0,000 4,375E-03 0,0104841 ! substrate-bound cell migration GO:0006929 13 11 0,000 4,375E-03 0,01047367 ! UV protection GO:0009650 19 11 0,000 4,375E-03 0,01046325 ! adult heart development GO:0007512 14 11 0,000 4,375E-03 0,01045286 ! chondrocyte differentiation GO:0002062 24 11 0,000 4,375E-03 0,01044249 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 4,375E-03 0,01043214 ! temperature homeostasis GO:0001659 17 11 0,000 4,375E-03 0,01042182 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 4,375E-03 0,01041151 ! negative regulation of ossification GO:0030279 26 11 0,000 4,375E-03 0,01040122 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 4,375E-03 0,01039095 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 4,375E-03 0,0103807 ! regulation of organ growth GO:0046620 13 11 0,000 4,375E-03 0,01037048 ! pigment granule localization GO:0051875 20 11 0,000 4,375E-03 0,01036027 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 4,375E-03 0,01035008 ! vasoconstriction GO:0042310 18 11 0,000 4,375E-03 0,01033992 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 4,375E-03 0,01032977 ! embryonic axis specification GO:0000578 18 11 0,000 4,375E-03 0,01031964 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 4,375E-03 0,01030953 ! snRNA metabolic process GO:0016073 24 11 0,000 4,375E-03 0,01029945 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 4,375E-03 0,01028938 ! nitric oxide metabolic process GO:0046209 15 11 0,000 4,375E-03 0,01027933 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 4,375E-03 0,0102693 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 4,375E-03 0,01025929 ! zymogen activation GO:0031638 15 11 0,000 4,375E-03 0,0102493 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 4,375E-03 0,01023933 ! neuroblast proliferation GO:0007405 24 11 0,000 4,375E-03 0,01022938 ! nucleosome positioning GO:0016584 15 11 0,000 4,375E-03 0,01021945 ! regulation of isotype switching GO:0045191 22 11 0,000 4,375E-03 0,01020954 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 4,375E-03 0,01019965 ! glutathione biosynthetic process GO:0006750 13 11 0,000 4,375E-03 0,01018977 ! regulation of leukocyte migration GO:0002685 26 11 0,000 4,375E-03 0,01017992 ! acid secretion GO:0046717 18 11 0,000 4,375E-03 0,01017008 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 4,375E-03 0,01016026 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 4,375E-03 0,01015047 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 4,375E-03 0,01014069 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 4,375E-03 0,01013093 ! oocyte differentiation GO:0009994 18 11 0,000 4,375E-03 0,01012119 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 4,375E-03 0,01011146 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 4,375E-03 0,01010176 ! cholesterol efflux GO:0033344 19 11 0,000 4,375E-03 0,01009207 ! anterior/posterior axis specification GO:0009948 18 11 0,000 4,375E-03 0,01008241 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 4,375E-03 0,01007276 ! negative regulation of glucose import GO:0046325 17 11 0,000 4,375E-03 0,01006313 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 4,375E-03 0,01005352 ! embryonic gut development GO:0048566 15 11 0,000 4,375E-03 0,01004393 ! regulation of organic acid transport GO:0032890 18 11 0,000 4,375E-03 0,01003435 ! cardiac cell differentiation GO:0035051 31 11 0,000 4,375E-03 0,01002479 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 4,375E-03 0,01001526 ! defense response to fungus GO:0050832 13 11 0,000 4,375E-03 0,01000574 ! developmental induction GO:0031128 19 11 0,000 4,375E-03 9,996E-03 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 4,375E-03 9,987E-03 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 4,375E-03 9,977E-03 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 4,375E-03 9,968E-03 ! sequestering of metal ion GO:0051238 14 11 0,000 4,375E-03 9,958E-03 ! lamellipodium assembly GO:0030032 20 11 0,000 4,375E-03 9,949E-03 ! regulation of embryonic development GO:0045995 27 11 0,000 4,375E-03 9,94E-03 ! nucleus localization GO:0051647 19 11 0,000 4,375E-03 9,93E-03 ! regulation of synapse organization GO:0050807 17 11 0,000 4,375E-03 9,921E-03 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 4,772E-03 0,01081059 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 4,772E-03 0,01080042 ! positive regulation of blood pressure GO:0045777 17 12 0,000 4,772E-03 0,01079027 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 4,772E-03 0,01078014 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 4,772E-03 0,01077003 ! virus-host interaction GO:0019048 29 12 0,000 4,772E-03 0,01075993 ! regulation of B cell proliferation GO:0030888 20 12 0,000 4,772E-03 0,01074986 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 4,772E-03 0,0107398 ! cartilage condensation GO:0001502 20 12 0,000 4,772E-03 0,01072977 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 4,772E-03 0,01071975 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 4,772E-03 0,01070975 ! protein complex disassembly GO:0043241 27 12 0,000 4,772E-03 0,01069977 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 4,772E-03 0,0106898 ! regulation of cell projection assembly GO:0060491 30 12 0,000 4,772E-03 0,01067986 ! hippocampus development GO:0021766 26 12 0,000 4,772E-03 0,01066993 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 4,772E-03 0,01066003 ! cytokine biosynthetic process GO:0042089 21 12 0,000 4,772E-03 0,01065014 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 4,772E-03 0,01064027 ! positive regulation of cell growth GO:0030307 22 12 0,000 4,772E-03 0,01063042 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 4,772E-03 0,01062058 ! regulation of exit from mitosis GO:0007096 17 12 0,000 4,772E-03 0,01061077 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 4,772E-03 0,01060097 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 4,772E-03 0,01059119 ! drug transport GO:0015893 16 12 0,000 4,772E-03 0,01058143 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 4,772E-03 0,01057169 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 4,772E-03 0,01056196 ! tyrosine metabolic process GO:0006570 16 12 0,000 4,772E-03 0,01055225 ! polyamine metabolic process GO:0006595 17 12 0,000 4,772E-03 0,01054256 ! focal adhesion formation GO:0048041 35 12 0,000 4,772E-03 0,01053289 ! mitotic spindle organization GO:0007052 21 12 0,000 4,772E-03 0,01052324 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 4,772E-03 0,0105136 ! forebrain cell migration GO:0021885 21 12 0,000 4,772E-03 0,01050398 ! asymmetric protein localization GO:0008105 20 12 0,000 4,772E-03 0,01049438 ! membrane protein proteolysis GO:0033619 25 12 0,000 4,772E-03 0,01048479 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 4,772E-03 0,01047523 ! entry into host cell GO:0030260 32 12 0,000 4,772E-03 0,01046568 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 4,772E-03 0,01045615 ! monoamine transport GO:0015844 18 12 0,000 4,772E-03 0,01044663 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 4,772E-03 0,01043714 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 4,772E-03 0,01042766 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 4,772E-03 0,01041819 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 4,772E-03 0,01040875 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 4,772E-03 0,01039932 ! protein targeting to peroxisome GO:0006625 23 12 0,000 4,772E-03 0,01038991 ! protein homotetramerization GO:0051289 21 12 0,000 4,772E-03 0,01038052 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 4,772E-03 0,01037114 ! regulation of phagocytosis GO:0050764 16 12 0,000 4,772E-03 0,01036178 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 4,772E-03 0,01035243 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 4,772E-03 0,01034311 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 4,772E-03 0,0103338 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 4,772E-03 0,01032451 ! cranial nerve development GO:0021545 20 12 0,000 4,772E-03 0,01031523 ! fucose catabolic process GO:0019317 22 12 0,000 4,772E-03 0,01030597 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 4,772E-03 0,01029673 ! histone acetylation GO:0016573 26 12 0,000 4,772E-03 0,0102875 ! histone methylation GO:0016571 26 12 0,000 4,772E-03 0,01027829 ! mRNA polyadenylation GO:0006378 23 12 0,000 4,772E-03 0,0102691 ! autonomic nervous system development GO:0048483 24 12 0,000 4,772E-03 0,01025992 ! gland morphogenesis GO:0022612 29 12 0,000 4,772E-03 0,01025076 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 4,772E-03 0,01024161 ! peptidyl-lysine modification GO:0018205 21 12 0,000 4,772E-03 0,01023249 ! T cell homeostasis GO:0043029 25 12 0,000 4,772E-03 0,01022337 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 4,772E-03 0,01021428 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 4,772E-03 0,0102052 ! spleen development GO:0048536 22 12 0,000 4,772E-03 0,01019614 ! digestive tract morphogenesis GO:0048546 26 12 0,000 4,772E-03 0,01018709 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 4,772E-03 0,01017806 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 4,772E-03 0,01016904 ! regulation of RNA splicing GO:0043484 20 12 0,000 4,772E-03 0,01016004 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 4,772E-03 0,01015106 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 4,772E-03 0,01014209 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 4,772E-03 0,01013314 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 4,772E-03 0,01012421 ! response to cold GO:0009409 17 12 0,000 4,772E-03 0,01011529 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 4,772E-03 0,01010638 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 4,772E-03 0,01009749 ! cGMP metabolic process GO:0046068 18 13 0,000 5,168E-03 0,01092734 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 5,168E-03 0,01091775 ! regulation of chemokine production GO:0032642 18 13 0,000 5,168E-03 0,01090817 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 5,168E-03 0,01089861 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 5,168E-03 0,01088907 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 5,168E-03 0,01087954 ! lipid localization GO:0010876 28 13 0,000 5,168E-03 0,01087003 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 5,168E-03 0,01086054 ! organelle fusion GO:0048284 32 13 0,000 5,168E-03 0,01085106 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 5,168E-03 0,0108416 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 5,168E-03 0,01083216 ! pseudouridine synthesis GO:0001522 17 13 0,000 5,168E-03 0,01082273 ! endocrine pancreas development GO:0031018 22 13 0,000 5,168E-03 0,01081332 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 5,168E-03 0,01080392 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 5,168E-03 0,01079455 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 5,168E-03 0,01078518 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 5,168E-03 0,01077584 ! methionine metabolic process GO:0006555 27 13 0,000 5,168E-03 0,01076651 ! plasma membrane organization GO:0007009 24 13 0,000 5,168E-03 0,01075719 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 5,168E-03 0,0107479 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 5,168E-03 0,01073862 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 5,168E-03 0,01072935 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 5,168E-03 0,0107201 ! cell-cell junction assembly GO:0007043 27 13 0,000 5,168E-03 0,01071087 ! response to X-ray GO:0010165 25 13 0,000 5,168E-03 0,01070165 ! cytokine metabolic process GO:0042107 22 13 0,000 5,168E-03 0,01069245 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 5,168E-03 0,01068326 ! exocrine system development GO:0035272 32 13 0,000 5,168E-03 0,01067409 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 5,168E-03 0,01066494 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 5,168E-03 0,0106558 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 5,168E-03 0,01064668 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 5,168E-03 0,01063757 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 5,168E-03 0,01062848 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 5,168E-03 0,0106194 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 5,168E-03 0,01061034 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 5,168E-03 0,01060129 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 5,168E-03 0,01059226 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 5,168E-03 0,01058325 ! regulation of cellular pH GO:0030641 22 13 0,000 5,168E-03 0,01057425 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 5,168E-03 0,01056527 ! ribosome assembly GO:0042255 17 13 0,000 5,168E-03 0,0105563 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 5,168E-03 0,01054734 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 5,168E-03 0,0105384 ! chromatin silencing GO:0006342 26 13 0,000 5,168E-03 0,01052948 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 5,168E-03 0,01052057 ! regulation of epidermis development GO:0045682 19 13 0,000 5,168E-03 0,01051168 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 5,168E-03 0,0105028 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 5,168E-03 0,01049394 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 5,168E-03 0,01048509 ! regulation of mRNA stability GO:0043488 31 13 0,000 5,168E-03 0,01047626 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 5,168E-03 0,01046744 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 5,168E-03 0,01045863 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 5,168E-03 0,01044985 ! mRNA 3'-end processing GO:0031124 24 13 0,000 5,168E-03 0,01044107 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 5,168E-03 0,01043231 ! embryonic placenta development GO:0001892 23 13 0,000 5,168E-03 0,01042357 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 5,168E-03 0,01041484 ! insulin secretion GO:0030073 23 13 0,000 5,168E-03 0,01040612 ! actin filament polymerization GO:0030041 24 13 0,000 5,168E-03 0,01039742 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 5,168E-03 0,01038874 ! acrosome reaction GO:0007340 18 13 0,000 5,168E-03 0,01038006 ! rRNA transcription GO:0009303 25 14 0,000 5,565E-03 0,01116717 ! lactation GO:0007595 26 14 0,000 5,565E-03 0,01115786 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 5,565E-03 0,01114857 ! reproductive cellular process GO:0048610 20 14 0,000 5,565E-03 0,0111393 ! tRNA modification GO:0006400 20 14 0,000 5,565E-03 0,01113004 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 5,565E-03 0,01112079 ! regulation of S phase GO:0033261 23 14 0,000 5,565E-03 0,01111156 ! water transport GO:0006833 21 14 0,000 5,565E-03 0,01110235 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 5,565E-03 0,01109315 ! non-recombinational repair GO:0000726 25 14 0,000 5,565E-03 0,01108397 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 5,565E-03 0,0110748 ! retina development in camera-type eye GO:0060041 27 14 0,000 5,565E-03 0,01106565 ! hair follicle morphogenesis GO:0031069 26 14 0,000 5,565E-03 0,01105651 ! RNA polyadenylation GO:0043631 30 14 0,000 5,565E-03 0,01104739 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 5,565E-03 0,01103828 ! palate development GO:0060021 31 14 0,000 5,565E-03 0,01102919 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 5,565E-03 0,01102011 ! regulated secretory pathway GO:0045055 23 14 0,000 5,565E-03 0,01101105 ! regulation of mRNA processing GO:0050684 24 14 0,000 5,565E-03 0,011002 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 5,565E-03 0,01099297 ! arginine metabolic process GO:0006525 17 14 0,000 5,565E-03 0,01098395 ! regulation of heart rate GO:0002027 24 14 0,000 5,565E-03 0,01097495 ! organic alcohol transport GO:0015850 29 14 0,000 5,565E-03 0,01096596 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 5,565E-03 0,01095698 ! negative regulation of caspase activity GO:0043154 22 14 0,000 5,565E-03 0,01094803 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 5,565E-03 0,01093908 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 5,565E-03 0,01093015 ! neutral amino acid transport GO:0015804 26 14 0,000 5,565E-03 0,01092124 ! L-amino acid transport GO:0015807 30 14 0,000 5,565E-03 0,01091234 ! bone mineralization GO:0030282 17 14 0,000 5,565E-03 0,01090345 ! stem cell development GO:0048864 43 14 0,000 5,565E-03 0,01089458 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 5,565E-03 0,01088572 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 5,565E-03 0,01087688 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 5,565E-03 0,01086805 ! cerebellum development GO:0021549 21 14 0,000 5,565E-03 0,01085923 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 5,565E-03 0,01085043 ! negative regulation of protein secretion GO:0050709 28 14 0,000 5,565E-03 0,01084165 ! response to gamma radiation GO:0010332 28 14 0,000 5,565E-03 0,01083288 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 5,565E-03 0,01082412 ! cofactor transport GO:0051181 26 14 0,000 5,565E-03 0,01081538 ! NADP metabolic process GO:0006739 24 14 0,000 5,565E-03 0,01080665 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 5,565E-03 0,01079793 ! protein-chromophore linkage GO:0018298 19 14 0,000 5,565E-03 0,01078923 ! intestinal absorption GO:0050892 25 14 0,000 5,565E-03 0,01078054 ! cAMP biosynthetic process GO:0006171 23 14 0,000 5,565E-03 0,01077187 ! oxygen transport GO:0015671 21 14 0,000 5,565E-03 0,01076321 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 5,565E-03 0,01075457 ! male genitalia development GO:0030539 24 14 0,000 5,565E-03 0,01074594 ! regulation of RNA stability GO:0043487 32 14 0,000 5,565E-03 0,01073732 ! regulation of axon extension GO:0030516 37 14 0,000 5,565E-03 0,01072871 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 5,565E-03 0,01072012 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 5,565E-03 0,01071155 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 5,961E-03 0,01146539 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 5,961E-03 0,01145623 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 5,961E-03 0,01144709 ! superoxide anion generation GO:0042554 20 15 0,000 5,961E-03 0,01143796 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 5,961E-03 0,01142885 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 5,961E-03 0,01141975 ! phospholipid catabolic process GO:0009395 22 15 0,000 5,961E-03 0,01141066 ! copper ion transport GO:0006825 20 15 0,000 5,961E-03 0,01140159 ! heterophilic cell adhesion GO:0007157 39 15 0,000 5,961E-03 0,01139254 ! cardiac muscle contraction GO:0060048 26 15 0,000 5,961E-03 0,0113835 ! sulfate transport GO:0008272 23 15 0,000 5,961E-03 0,01137447 ! response to cAMP GO:0051591 22 15 0,000 5,961E-03 0,01136546 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 5,961E-03 0,01135646 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 5,961E-03 0,01134747 ! ciliary or flagellar motility GO:0001539 20 15 0,000 5,961E-03 0,0113385 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 5,961E-03 0,01132955 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 5,961E-03 0,0113206 ! response to hexose stimulus GO:0009746 22 15 0,000 5,961E-03 0,01131168 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 5,961E-03 0,01130276 ! glycoprotein catabolic process GO:0006516 26 15 0,000 5,961E-03 0,01129386 ! pituitary gland development GO:0021983 29 15 0,000 5,961E-03 0,01128498 ! vesicle coating GO:0006901 33 15 0,000 5,961E-03 0,0112761 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 5,961E-03 0,01126725 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 5,961E-03 0,0112584 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 5,961E-03 0,01124957 ! regulation of exocytosis GO:0017157 22 15 0,000 5,961E-03 0,01124076 ! G1/S transition checkpoint GO:0031575 40 15 0,000 5,961E-03 0,01123195 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 5,961E-03 0,01122317 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 5,961E-03 0,01121439 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 5,961E-03 0,01120563 ! regulation of vasodilation GO:0042312 26 15 0,000 5,961E-03 0,01119688 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 5,961E-03 0,01118815 ! histone deacetylation GO:0016575 20 15 0,000 5,961E-03 0,01117943 ! mRNA splice site selection GO:0006376 38 15 0,000 5,961E-03 0,01117072 ! tissue regeneration GO:0042246 26 15 0,000 5,961E-03 0,01116203 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 5,961E-03 0,01115335 ! water homeostasis GO:0030104 27 15 0,000 5,961E-03 0,01114468 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 5,961E-03 0,01113603 ! muscle maintenance GO:0046716 26 15 0,000 5,961E-03 0,01112739 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 5,961E-03 0,01111876 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 5,961E-03 0,01111015 ! regulation of ATPase activity GO:0043462 21 15 0,000 5,961E-03 0,01110155 ! dopamine metabolic process GO:0042417 35 15 0,000 5,961E-03 0,01109297 ! heme biosynthetic process GO:0006783 29 15 0,000 5,961E-03 0,01108439 ! cell killing GO:0001906 29 15 0,000 5,961E-03 0,01107583 ! lymphocyte homeostasis GO:0002260 30 15 0,000 5,961E-03 0,01106729 ! detection of bacterium GO:0016045 18 15 0,000 5,961E-03 0,01105875 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 5,961E-03 0,01105023 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 5,961E-03 0,01104173 ! L-fucose metabolic process GO:0042354 30 15 0,000 5,961E-03 0,01103323 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 5,961E-03 0,01102475 ! peptide hormone processing GO:0016486 23 15 0,000 5,961E-03 0,01101629 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 6,358E-03 0,01173954 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 6,358E-03 0,01173054 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 6,358E-03 0,01172155 ! dicarboxylic acid transport GO:0006835 38 16 0,000 6,358E-03 0,01171258 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 6,358E-03 0,01170362 ! bone remodeling GO:0046849 27 16 0,000 6,358E-03 0,01169467 ! filopodium assembly GO:0046847 32 16 0,000 6,358E-03 0,01168573 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 6,358E-03 0,01167681 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 6,358E-03 0,01166791 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 6,358E-03 0,01165901 ! positive regulation of ion transport GO:0043270 21 16 0,000 6,358E-03 0,01165013 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 6,358E-03 0,01164127 ! startle response GO:0001964 28 16 0,000 6,358E-03 0,01163242 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 6,358E-03 0,01162358 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 6,358E-03 0,01161475 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 6,358E-03 0,01160594 ! activation of MAPKK activity GO:0000186 35 16 0,000 6,358E-03 0,01159714 ! regulation of defense response to virus GO:0050688 27 16 0,000 6,358E-03 0,01158835 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 6,358E-03 0,01157958 ! protein polyubiquitination GO:0000209 34 16 0,000 6,358E-03 0,01157082 ! glutamate metabolic process GO:0006536 22 16 0,000 6,358E-03 0,01156208 ! complement activation, alternative pathway GO:0006957 18 16 0,000 6,358E-03 0,01155334 ! response to osmotic stress GO:0006970 25 16 0,000 6,358E-03 0,01154462 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 6,358E-03 0,01153592 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 6,358E-03 0,01152722 ! fructose metabolic process GO:0006000 25 16 0,000 6,358E-03 0,01151854 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 6,358E-03 0,01150988 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 32 16 0,000 6,358E-03 0,01150122 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 6,358E-03 0,01149258 ! negative regulation of immune response GO:0050777 35 16 0,000 6,358E-03 0,01148395 ! axon cargo transport GO:0008088 43 16 0,000 6,358E-03 0,01147534 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 6,358E-03 0,01146674 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 6,358E-03 0,01145815 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 6,358E-03 0,01144957 ! DNA replication initiation GO:0006270 27 16 0,000 6,358E-03 0,01144101 ! neuron recognition GO:0008038 35 16 0,000 6,358E-03 0,01143246 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 6,358E-03 0,01142392 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 6,358E-03 0,01141539 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 6,358E-03 0,01140688 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 6,358E-03 0,01139838 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 6,358E-03 0,01138989 ! sphingolipid catabolic process GO:0030149 27 16 0,000 6,358E-03 0,01138142 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 6,358E-03 0,01137296 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 6,358E-03 0,01136451 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 6,358E-03 0,01135607 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 6,358E-03 0,01134765 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 6,358E-03 0,01133923 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 6,358E-03 0,01133083 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 6,358E-03 0,01132245 ! defense response to virus GO:0051607 37 16 0,000 6,358E-03 0,01131407 ! positive regulation of cell killing GO:0031343 32 17 0,000 6,754E-03 0,01201012 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 6,754E-03 0,01200125 ! metencephalon development GO:0022037 30 17 0,000 6,754E-03 0,0119924 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 6,754E-03 0,01198355 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 6,754E-03 0,01197472 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 6,754E-03 0,0119659 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 6,754E-03 0,0119571 ! signal complex assembly GO:0007172 41 17 0,000 6,754E-03 0,01194831 ! endothelial cell migration GO:0043542 28 17 0,000 6,754E-03 0,01193953 ! inositol metabolic process GO:0006020 28 17 0,000 6,754E-03 0,01193076 ! gene silencing by RNA GO:0031047 36 17 0,000 6,754E-03 0,01192201 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 6,754E-03 0,01191327 ! glial cell development GO:0021782 27 17 0,000 6,754E-03 0,01190454 ! limbic system development GO:0021761 36 17 0,000 6,754E-03 0,01189583 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 6,754E-03 0,01188712 ! adult walking behavior GO:0007628 33 17 0,000 6,754E-03 0,01187843 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 6,754E-03 0,01186976 ! heart looping GO:0001947 30 17 0,000 6,754E-03 0,01186109 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 6,754E-03 0,01185244 ! regulation of viral genome replication GO:0045069 28 17 0,000 6,754E-03 0,0118438 ! myoblast differentiation GO:0045445 45 17 0,000 6,754E-03 0,01183518 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 6,754E-03 0,01182656 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 6,754E-03 0,01181796 ! regulation of survival gene product expression GO:0045884 33 17 0,000 6,754E-03 0,01180937 ! cardiac muscle tissue development GO:0048738 31 17 0,000 6,754E-03 0,0118008 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 6,754E-03 0,01179223 ! glycine metabolic process GO:0006544 28 17 0,000 6,754E-03 0,01178368 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 6,754E-03 0,01177514 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 6,754E-03 0,01176662 ! NAD metabolic process GO:0019674 29 17 0,000 6,754E-03 0,0117581 ! membrane budding GO:0006900 37 17 0,000 6,754E-03 0,0117496 ! DNA integration GO:0015074 29 17 0,000 6,754E-03 0,01174111 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 6,754E-03 0,01173263 ! regulation of protein binding GO:0043393 33 17 0,000 6,754E-03 0,01172417 ! nucleobase metabolic process GO:0009112 37 17 0,000 6,754E-03 0,01171572 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 6,754E-03 0,01170728 ! DNA unwinding during replication GO:0006268 27 17 0,000 6,754E-03 0,01169885 ! genitalia development GO:0048806 30 17 0,000 6,754E-03 0,01169043 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 6,754E-03 0,01168203 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 6,754E-03 0,01167363 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 6,754E-03 0,01166525 ! neutrophil chemotaxis GO:0030593 27 17 0,000 6,754E-03 0,01165689 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 6,754E-03 0,01164853 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 6,754E-03 0,01164019 ! steroid catabolic process GO:0006706 31 17 0,000 6,754E-03 0,01163185 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 6,754E-03 0,01162353 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 6,754E-03 0,01161522 ! gas transport GO:0015669 25 17 0,000 6,754E-03 0,01160693 ! organic cation transport GO:0015695 31 17 0,000 6,754E-03 0,01159864 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 6,754E-03 0,01159037 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 6,754E-03 0,01158211 ! RNA 3'-end processing GO:0031123 34 17 0,000 6,754E-03 0,01157386 ! microspike assembly GO:0030035 36 17 0,000 6,754E-03 0,01156562 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 6,754E-03 0,0115574 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 6,754E-03 0,01154918 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 7,15E-03 0,01221763 ! neuron maturation GO:0042551 42 18 0,000 7,15E-03 0,01220896 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 7,15E-03 0,0122003 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 7,15E-03 0,01219165 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 7,15E-03 0,01218302 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 7,15E-03 0,0121744 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 7,15E-03 0,01216579 ! aminoglycan catabolic process GO:0006026 22 18 0,000 7,15E-03 0,01215719 ! memory GO:0007613 31 18 0,000 7,15E-03 0,0121486 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 7,15E-03 0,01214003 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 7,15E-03 0,01213147 ! patterning of blood vessels GO:0001569 39 18 0,000 7,15E-03 0,01212292 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 7,15E-03 0,01211438 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 7,15E-03 0,01210586 ! positive regulation of proteolysis GO:0045862 31 18 0,000 7,15E-03 0,01209734 ! epidermis morphogenesis GO:0048730 40 18 0,000 7,15E-03 0,01208884 ! glutamine metabolic process GO:0006541 29 18 0,000 7,15E-03 0,01208035 ! response to retinoic acid GO:0032526 26 18 0,000 7,15E-03 0,01207188 ! cell-substrate junction assembly GO:0007044 54 18 0,000 7,15E-03 0,01206341 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 7,15E-03 0,01205496 ! response to fungus GO:0009620 21 18 0,000 7,15E-03 0,01204651 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 7,15E-03 0,01203808 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 7,15E-03 0,01202967 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 7,15E-03 0,01202126 ! long-chain fatty acid transport GO:0015909 31 18 0,000 7,15E-03 0,01201287 ! peptide biosynthetic process GO:0043043 24 18 0,000 7,15E-03 0,01200448 ! vitamin transport GO:0051180 27 18 0,000 7,15E-03 0,01199611 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 7,15E-03 0,01198775 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 7,15E-03 0,0119794 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 7,15E-03 0,01197107 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 7,15E-03 0,01196274 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 7,15E-03 0,01195443 ! aromatic compound catabolic process GO:0019439 27 18 0,000 7,15E-03 0,01194613 ! nerve development GO:0021675 28 18 0,000 7,15E-03 0,01193784 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 7,15E-03 0,01192956 ! protein secretion GO:0009306 39 19 0,000 7,546E-03 0,01258129 ! positive regulation of translation GO:0045727 30 19 0,000 7,546E-03 0,01257258 ! negative regulation of defense response GO:0031348 25 19 0,000 7,546E-03 0,01256387 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 7,546E-03 0,01255519 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 7,546E-03 0,01254651 ! skin development GO:0043588 36 19 0,000 7,546E-03 0,01253784 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 7,546E-03 0,01252919 ! lipid phosphorylation GO:0046834 35 19 0,000 7,546E-03 0,01252055 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 7,546E-03 0,01251192 ! forelimb morphogenesis GO:0035136 32 19 0,000 7,546E-03 0,01250331 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 7,546E-03 0,0124947 ! bile acid metabolic process GO:0008206 29 19 0,000 7,546E-03 0,01248611 ! mitotic chromosome condensation GO:0007076 34 19 0,000 7,546E-03 0,01247753 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 7,546E-03 0,01246896 ! cerebral cortex development GO:0021987 36 19 0,000 7,546E-03 0,0124604 ! pigmentation during development GO:0048066 41 19 0,000 7,546E-03 0,01245185 ! response to vitamin A GO:0033189 27 19 0,000 7,546E-03 0,01244332 ! heme metabolic process GO:0042168 36 19 0,000 7,546E-03 0,01243479 ! actin filament bundle formation GO:0051017 42 19 0,000 7,546E-03 0,01242628 ! neuromuscular junction development GO:0007528 34 19 0,000 7,546E-03 0,01241778 ! response to lipopolysaccharide GO:0032496 30 19 0,000 7,546E-03 0,0124093 ! plasma membrane fusion GO:0045026 28 19 0,000 7,546E-03 0,01240082 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 7,546E-03 0,01239235 ! peptide cross-linking GO:0018149 37 19 0,000 7,546E-03 0,0123839 ! protein export from nucleus GO:0006611 36 19 0,000 7,546E-03 0,01237546 ! heart process GO:0003015 30 19 0,000 7,546E-03 0,01236703 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 7,546E-03 0,01235861 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 7,546E-03 0,0123502 ! visual learning GO:0008542 36 19 0,000 7,546E-03 0,01234181 ! cellular pigmentation GO:0033059 36 19 0,000 7,546E-03 0,01233342 ! G1 phase GO:0051318 40 19 0,000 7,546E-03 0,01232505 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 7,546E-03 0,01231669 ! cell-cell junction organization GO:0045216 35 19 0,000 7,546E-03 0,01230834 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 7,546E-03 0,0123 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 7,546E-03 0,01229167 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 7,546E-03 0,01228336 ! proximal/distal pattern formation GO:0009954 32 19 0,000 7,546E-03 0,01227505 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 7,546E-03 0,01226676 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 7,546E-03 0,01225847 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 7,546E-03 0,0122502 ! cilium assembly GO:0042384 37 19 0,000 7,546E-03 0,01224194 ! peptide hormone secretion GO:0030072 31 19 0,000 7,546E-03 0,01223369 ! protein import into nucleus, docking GO:0000059 41 20 0,000 7,941E-03 0,01286655 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 7,941E-03 0,01285789 ! positive regulation of ossification GO:0045778 47 20 0,000 7,941E-03 0,01284925 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 7,941E-03 0,01284061 ! protein amino acid deacetylation GO:0006476 29 20 0,000 7,941E-03 0,01283199 ! protein amino acid acetylation GO:0006473 39 20 0,000 7,941E-03 0,01282337 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 7,941E-03 0,01281477 ! cAMP metabolic process GO:0046058 36 20 0,000 7,941E-03 0,01280618 ! response to vitamin GO:0033273 31 20 0,000 7,941E-03 0,01279761 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 7,941E-03 0,01278904 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 7,941E-03 0,01278049 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 7,941E-03 0,01277194 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 7,941E-03 0,01276341 ! response to alkaloid GO:0043279 38 20 0,000 7,941E-03 0,01275489 ! retinoid metabolic process GO:0001523 32 20 0,000 7,941E-03 0,01274638 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 7,941E-03 0,01273788 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 7,941E-03 0,0127294 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 7,941E-03 0,01272092 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 7,941E-03 0,01271246 ! DNA duplex unwinding GO:0032508 31 20 0,000 7,941E-03 0,01270401 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 7,941E-03 0,01269557 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 7,941E-03 0,01268714 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 7,941E-03 0,01267872 ! D-ribose metabolic process GO:0006014 29 20 0,000 7,941E-03 0,01267031 ! body fluid secretion GO:0007589 31 20 0,000 7,941E-03 0,01266191 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 7,941E-03 0,01265353 ! peptide secretion GO:0002790 35 20 0,000 7,941E-03 0,01264515 ! stem cell differentiation GO:0048863 53 20 0,000 7,941E-03 0,01263679 ! behavioral interaction between organisms GO:0051705 38 20 0,000 7,941E-03 0,01262844 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 7,941E-03 0,0126201 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 7,941E-03 0,01261177 ! sensory perception of pain GO:0019233 30 20 0,000 7,941E-03 0,01260345 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 7,941E-03 0,01259514 ! diencephalon development GO:0021536 34 20 0,000 7,941E-03 0,01258684 ! protein localization in mitochondrion GO:0070585 32 20 0,000 7,941E-03 0,01257856 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 7,941E-03 0,01257028 ! detection of chemical stimulus GO:0009593 37 20 0,000 7,941E-03 0,01256202 ! peptidyl-serine modification GO:0018209 43 20 0,000 7,941E-03 0,01255376 ! positive regulation of neurological system process GO:0031646 32 20 0,000 7,941E-03 0,01254552 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 7,941E-03 0,01253729 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 7,941E-03 0,01252907 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 7,941E-03 0,01252086 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 7,941E-03 0,01251266 ! regulation of glucose import GO:0046324 29 20 0,000 7,941E-03 0,01250447 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 7,941E-03 0,01249629 ! actin filament-based movement GO:0030048 43 20 0,000 7,941E-03 0,01248812 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 7,941E-03 0,01247997 ! negative regulation of T cell activation GO:0050868 40 20 0,000 7,941E-03 0,01247182 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 7,941E-03 0,01246368 ! negative regulation of coagulation GO:0050819 29 20 0,000 7,941E-03 0,01245556 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 7,941E-03 0,01244744 ! regulation of cell killing GO:0031341 42 21 0,000 8,337E-03 0,01305892 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 8,337E-03 0,01305043 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 8,337E-03 0,01304194 ! hormone secretion GO:0046879 38 21 0,000 8,337E-03 0,01303347 ! glycerol metabolic process GO:0006071 34 21 0,000 8,337E-03 0,013025 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 8,337E-03 0,01301655 ! hindlimb morphogenesis GO:0035137 43 21 0,000 8,337E-03 0,01300811 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 8,337E-03 0,01299968 ! axis specification GO:0009798 38 21 0,000 8,337E-03 0,01299126 ! ovarian follicle development GO:0001541 35 21 0,000 8,337E-03 0,01298285 ! inactivation of MAPK activity GO:0000188 39 21 0,000 8,337E-03 0,01297446 ! smooth muscle contraction GO:0006939 46 21 0,000 8,337E-03 0,01296607 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 8,337E-03 0,01295769 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 8,337E-03 0,01294933 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 8,337E-03 0,01294097 ! cell aging GO:0007569 44 21 0,000 8,337E-03 0,01293263 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 8,337E-03 0,0129243 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 8,337E-03 0,01291597 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 8,337E-03 0,01290766 ! cytolysis GO:0019835 24 21 0,000 8,337E-03 0,01289936 ! vasodilation GO:0042311 39 21 0,000 8,337E-03 0,01289107 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 8,337E-03 0,01288279 ! regulation of vasoconstriction GO:0019229 39 21 0,000 8,337E-03 0,01287452 ! oogenesis GO:0048477 36 21 0,000 8,337E-03 0,01286627 ! DNA modification GO:0006304 34 21 0,000 8,337E-03 0,01285802 ! positive regulation of locomotion GO:0040017 39 21 0,000 8,337E-03 0,01284978 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 8,337E-03 0,01284155 ! detection of biotic stimulus GO:0009595 29 21 0,000 8,337E-03 0,01283334 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 8,337E-03 0,01282513 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 8,337E-03 0,01281694 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 8,337E-03 0,01280875 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 8,337E-03 0,01280058 ! vitamin A metabolic process GO:0006776 33 21 0,000 8,337E-03 0,01279242 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 8,337E-03 0,01278426 ! response to cytokine stimulus GO:0034097 63 21 0,000 8,337E-03 0,01277612 ! terpenoid metabolic process GO:0006721 37 21 0,000 8,337E-03 0,01276799 ! collagen catabolic process GO:0030574 28 21 0,000 8,337E-03 0,01275986 ! sperm-egg recognition GO:0035036 21 21 0,000 8,337E-03 0,01275175 ! gut development GO:0048565 39 21 0,000 8,337E-03 0,01274365 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 8,732E-03 0,01333958 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 8,732E-03 0,01333112 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 8,732E-03 0,01332266 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 8,732E-03 0,01331422 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 8,732E-03 0,01330579 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 8,732E-03 0,01329737 ! regulation of chemotaxis GO:0050920 40 22 0,000 8,732E-03 0,01328896 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 8,732E-03 0,01328056 ! glutamate signaling pathway GO:0007215 41 22 0,000 8,732E-03 0,01327217 ! regeneration GO:0031099 41 22 0,000 8,732E-03 0,01326379 ! keratinization GO:0031424 28 22 0,000 8,732E-03 0,01325542 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 8,732E-03 0,01324706 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 8,732E-03 0,01323871 ! sensory perception of taste GO:0050909 28 22 0,000 8,732E-03 0,01323038 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 8,732E-03 0,01322205 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 8,732E-03 0,01321374 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 8,732E-03 0,01320543 ! vacuolar transport GO:0007034 36 22 0,000 8,732E-03 0,01319714 ! lysosome organization GO:0007040 41 22 0,000 8,732E-03 0,01318885 ! central nervous system neuron development GO:0021954 46 22 0,000 8,732E-03 0,01318058 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 8,732E-03 0,01317231 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 8,732E-03 0,01316406 ! fucose metabolic process GO:0006004 39 22 0,000 8,732E-03 0,01315582 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 8,732E-03 0,01314758 ! apoptotic nuclear changes GO:0030262 32 22 0,000 8,732E-03 0,01313936 ! ureteric bud development GO:0001657 43 22 0,000 8,732E-03 0,01313115 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 8,732E-03 0,01312295 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 8,732E-03 0,01311476 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 8,732E-03 0,01310658 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 8,732E-03 0,0130984 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 8,732E-03 0,01309024 ! regulation of cytokine secretion GO:0050707 37 22 0,000 8,732E-03 0,01308209 ! sarcomere organization GO:0045214 30 22 0,000 8,732E-03 0,01307395 ! positive regulation of B cell activation GO:0050871 38 22 0,000 8,732E-03 0,01306582 ! activation of JUN kinase activity GO:0007257 42 22 0,000 8,732E-03 0,0130577 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 8,732E-03 0,01304959 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 8,732E-03 0,01304149 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 8,732E-03 0,0130334 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 8,732E-03 0,01302532 ! protein stabilization GO:0050821 39 22 0,000 8,732E-03 0,01301725 ! positive regulation of DNA replication GO:0045740 43 23 0,000 9,128E-03 0,01359803 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 9,128E-03 0,01358962 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 9,128E-03 0,01358121 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 9,128E-03 0,01357282 ! gluconeogenesis GO:0006094 33 23 0,000 9,128E-03 0,01356444 ! viral genome replication GO:0019079 41 23 0,000 9,128E-03 0,01355606 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 9,128E-03 0,0135477 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 9,128E-03 0,01353935 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 9,128E-03 0,01353101 ! glucosamine metabolic process GO:0006041 30 23 0,000 9,128E-03 0,01352268 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 9,128E-03 0,01351435 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 9,128E-03 0,01350604 ! visual behavior GO:0007632 42 23 0,000 9,128E-03 0,01349774 ! regulation of DNA recombination GO:0000018 48 23 0,000 9,128E-03 0,01348945 ! response to ethanol GO:0045471 46 23 0,000 9,128E-03 0,01348117 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 9,128E-03 0,0134729 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 9,128E-03 0,01346464 ! peroxisome organization GO:0007031 37 23 0,000 9,128E-03 0,01345639 ! polysaccharide catabolic process GO:0000272 27 23 0,000 9,128E-03 0,01344815 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 9,128E-03 0,01343992 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 9,128E-03 0,0134317 ! barbed-end actin filament capping GO:0051016 50 23 0,000 9,128E-03 0,01342349 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 9,128E-03 0,01341529 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 9,128E-03 0,0134071 ! regulation of viral reproduction GO:0050792 38 23 0,000 9,128E-03 0,01339892 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 9,128E-03 0,01339075 ! leukotriene metabolic process GO:0006691 42 23 0,000 9,128E-03 0,01338259 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 9,128E-03 0,01337444 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 9,128E-03 0,0133663 ! synaptic vesicle transport GO:0048489 46 23 0,000 9,128E-03 0,01335817 ! fatty acid transport GO:0015908 44 23 0,000 9,128E-03 0,01335005 ! platelet activation GO:0030168 37 23 0,000 9,128E-03 0,01334193 ! regulation of bone mineralization GO:0030500 49 23 0,000 9,128E-03 0,01333383 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 9,128E-03 0,01332574 ! hormone transport GO:0009914 40 23 0,000 9,128E-03 0,01331766 ! cell-cell recognition GO:0009988 25 23 0,000 9,128E-03 0,01330959 ! negative regulation of cytokine production GO:0001818 40 23 0,000 9,128E-03 0,01330153 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 9,128E-03 0,01329348 ! negative regulation of catabolic process GO:0009895 50 23 0,000 9,128E-03 0,01328544 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 9,128E-03 0,0132774 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 9,128E-03 0,01326938 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 9,523E-03 0,01383542 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 9,523E-03 0,01382707 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 9,523E-03 0,01381873 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 9,523E-03 0,0138104 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 9,523E-03 0,01380209 ! regulation of transmembrane transport GO:0034762 38 24 0,000 9,523E-03 0,01379378 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 9,523E-03 0,01378548 ! vesicle docking GO:0048278 47 24 0,000 9,523E-03 0,01377719 ! spinal cord development GO:0021510 47 24 0,000 9,523E-03 0,01376891 ! vacuole organization GO:0007033 43 24 0,000 9,523E-03 0,01376064 ! multicellular organismal response to stress GO:0033555 49 24 0,000 9,523E-03 0,01375238 ! digestive system process GO:0022600 39 24 0,000 9,523E-03 0,01374413 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 9,523E-03 0,01373589 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 9,523E-03 0,01372766 ! regulation of behavior GO:0050795 43 24 0,000 9,523E-03 0,01371944 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 9,523E-03 0,01371123 ! lymphocyte proliferation GO:0046651 48 24 0,000 9,523E-03 0,01370303 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 9,523E-03 0,01369484 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 9,523E-03 0,01368666 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 9,523E-03 0,01367848 ! membrane depolarization GO:0051899 39 24 0,000 9,523E-03 0,01367032 ! pallium development GO:0021543 49 24 0,000 9,523E-03 0,01366217 ! pentose metabolic process GO:0019321 35 24 0,000 9,523E-03 0,01365403 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 9,523E-03 0,0136459 ! leukocyte homeostasis GO:0001776 44 24 0,000 9,523E-03 0,01363777 ! cellular alkene metabolic process GO:0043449 43 24 0,000 9,523E-03 0,01362966 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 9,523E-03 0,01362156 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 9,523E-03 0,01361346 ! porphyrin metabolic process GO:0006778 46 24 0,000 9,523E-03 0,01360538 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 9,523E-03 0,01359731 ! regulation of multi-organism process GO:0043900 36 24 0,000 9,523E-03 0,01358924 ! regulation of amine transport GO:0051952 40 24 0,000 9,523E-03 0,01358119 ! protein tetramerization GO:0051262 52 24 0,000 9,523E-03 0,01357314 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 9,918E-03 0,01412774 ! myelination GO:0042552 45 25 0,000 9,918E-03 0,01411938 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 9,918E-03 0,01411103 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 9,918E-03 0,01410269 ! phototransduction GO:0007602 33 25 0,000 9,918E-03 0,01409436 ! protein amino acid alkylation GO:0008213 53 25 0,000 9,918E-03 0,01408604 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 9,918E-03 0,01407773 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 9,918E-03 0,01406943 ! sperm motility GO:0030317 31 25 0,000 9,918E-03 0,01406114 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 9,918E-03 0,01405286 ! negative regulation of DNA replication GO:0008156 42 25 0,000 9,918E-03 0,01404459 ! receptor metabolic process GO:0043112 46 25 0,000 9,918E-03 0,01403632 ! chromosome condensation GO:0030261 45 25 0,000 9,918E-03 0,01402807 ! response to starvation GO:0042594 42 25 0,000 9,918E-03 0,01401983 ! osteoblast differentiation GO:0001649 60 25 0,000 9,918E-03 0,0140116 ! neural crest cell development GO:0014032 54 25 0,000 9,918E-03 0,01400337 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 9,918E-03 0,01399516 ! negative regulation of cell development GO:0010721 73 25 0,000 9,918E-03 0,01398696 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 9,918E-03 0,01397876 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 9,918E-03 0,01397058 ! interaction with host GO:0051701 62 25 0,000 9,918E-03 0,01396241 ! regulation of biomineral formation GO:0070167 51 25 0,000 9,918E-03 0,01395424 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 9,918E-03 0,01394608 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 9,918E-03 0,01393794 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 9,918E-03 0,0139298 ! immunoglobulin production GO:0002377 55 25 0,000 9,918E-03 0,01392168 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 9,918E-03 0,01391356 ! positive regulation of protein secretion GO:0050714 36 25 0,000 9,918E-03 0,01390545 ! regulation of blood coagulation GO:0030193 40 25 0,000 9,918E-03 0,01389735 ! cellular response to nutrient levels GO:0031669 41 25 0,000 9,918E-03 0,01388926 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 9,918E-03 0,01388118 ! telomere organization GO:0032200 43 25 0,000 9,918E-03 0,01387311 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 9,918E-03 0,01386505 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 9,918E-03 0,013857 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,01031242 0,01440029 ! embryonic pattern specification GO:0009880 44 26 0,000 0,01031242 0,01439193 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,01031242 0,01438359 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,01031242 0,01437526 ! initiation of viral infection GO:0019059 57 26 0,000 0,01031242 0,01436693 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,01031242 0,01435862 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,01031242 0,01435031 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,01031242 0,01434202 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,01031242 0,01433373 ! molting cycle process GO:0022404 50 26 0,000 0,01031242 0,01432546 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,01031242 0,01431719 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,01031242 0,01430893 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,01031242 0,01430069 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,01031242 0,01429245 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,01031242 0,01428422 GO:0051297|centrosome organization, ! insulin receptor signaling pathway GO:0008286 64 26 0,000 0,01031242 0,014276 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,01031242 0,01426779 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,01031242 0,01425959 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,01031242 0,0142514 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,01031242 0,01424322 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,01031242 0,01423505 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,01031242 0,01422689 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,01031242 0,01421874 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,01031242 0,01421059 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,01031242 0,01420246 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,01031242 0,01419433 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,01031242 0,01418622 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,01031242 0,01417811 ! blastocyst development GO:0001824 49 26 0,000 0,01031242 0,01417001 ! leukocyte proliferation GO:0070661 52 26 0,000 0,01031242 0,01416193 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,01031242 0,01415385 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,01031242 0,01414578 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,0107071 0,0146788 ! neuron fate commitment GO:0048663 48 27 0,000 0,0107071 0,01467044 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,0107071 0,01466209 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,0107071 0,01465375 ! iron ion transport GO:0006826 59 27 0,000 0,0107071 0,01464542 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,0107071 0,0146371 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,0107071 0,01462878 ! protein amino acid acylation GO:0043543 55 27 0,000 0,0107071 0,01462048 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,0107071 0,01461219 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,0107071 0,0146039 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,0107071 0,01459563 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,0107071 0,01458737 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,0107071 0,01457911 ! autophagy GO:0006914 41 27 0,000 0,0107071 0,01457086 ! male gonad development GO:0008584 44 27 0,000 0,0107071 0,01456263 ! response to toxin GO:0009636 47 27 0,000 0,0107071 0,0145544 ! primary neural tube formation GO:0014020 51 27 0,000 0,0107071 0,01454618 ! base-excision repair GO:0006284 41 27 0,000 0,0107071 0,01453797 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,0107071 0,01452977 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,0107071 0,01452158 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,0107071 0,0145134 ! glutathione metabolic process GO:0006749 39 27 0,000 0,0107071 0,01450523 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,0107071 0,01449707 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,0107071 0,01448891 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,0107071 0,01448077 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,0107071 0,01447263 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,01110164 0,01499749 ! circadian rhythm GO:0007623 50 28 0,000 0,01110164 0,01498908 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,01110164 0,01498067 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,01110164 0,01497227 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,01110164 0,01496389 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,01110164 0,01495551 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,01110164 0,01494714 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,01110164 0,01493878 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,01110164 0,01493043 ! synaptogenesis GO:0007416 42 28 0,000 0,01110164 0,01492209 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,01110164 0,01491376 ! lipid oxidation GO:0034440 43 28 0,000 0,01110164 0,01490543 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,01110164 0,01489712 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,01110164 0,01488882 ! translational initiation GO:0006413 65 29 0,000 0,01149603 0,01540916 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,01149603 0,01540058 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,01149603 0,01539201 ! regulation of pH GO:0006885 43 29 0,000 0,01149603 0,01538345 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,01149603 0,0153749 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,01149603 0,01536635 ! catechol metabolic process GO:0009712 54 29 0,000 0,01149603 0,01535782 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,01149603 0,0153493 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,01149603 0,01534079 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,01149603 0,01533228 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,01149603 0,01532379 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,01149603 0,0153153 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,01149603 0,01530683 ! cell fate determination GO:0001709 60 29 0,000 0,01149603 0,01529836 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,01149603 0,0152899 ! detection of light stimulus GO:0009583 38 29 0,000 0,01149603 0,01528146 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 0,01149603 0,01527302 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,01149603 0,01526459 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,01149603 0,01525617 ! tissue homeostasis GO:0001894 48 29 0,000 0,01149603 0,01524776 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,01149603 0,01523936 ! phenol metabolic process GO:0018958 55 30 0,000 0,01189027 0,0157533 ! zinc ion transport GO:0006829 45 30 0,000 0,01189027 0,01574463 ! membrane docking GO:0022406 61 30 0,000 0,01189027 0,01573597 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,01189027 0,01572732 ! cell junction assembly GO:0034329 78 30 0,000 0,01189027 0,01571868 ! regulation of innate immune response GO:0045088 51 30 0,000 0,01189027 0,01571004 ! acute-phase response GO:0006953 49 30 0,000 0,01189027 0,01570142 ! myofibril assembly GO:0030239 47 30 0,000 0,01189027 0,01569281 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,01189027 0,01568421 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,01189027 0,01567561 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,01189027 0,01566703 ! phospholipid transport GO:0015914 51 30 0,000 0,01189027 0,01565845 ! ensheathment of neurons GO:0007272 57 30 0,000 0,01189027 0,01564989 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,01189027 0,01564133 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,01189027 0,01563278 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,01189027 0,01562424 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,01189027 0,01561572 ! eye morphogenesis GO:0048592 60 30 0,000 0,01189027 0,0156072 ! regulation of B cell activation GO:0050864 50 30 0,000 0,01189027 0,01559869 ! response to heat GO:0009408 50 30 0,000 0,01189027 0,01559019 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,01228437 0,01609815 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,01228437 0,01608938 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,01228437 0,01608063 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,01228437 0,01607189 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,01228437 0,01606315 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,01228437 0,01605443 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,01228437 0,01604571 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,01228437 0,016037 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,01228437 0,01602831 ! ovulation cycle process GO:0022602 49 31 0,000 0,01228437 0,01601962 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,01228437 0,01601094 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,01228437 0,01600227 ! peptide transport GO:0015833 55 31 0,000 0,01228437 0,01599361 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,01228437 0,01598496 ! iron ion homeostasis GO:0055072 54 31 0,000 0,01228437 0,01597632 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,01228437 0,01596769 ! mesoderm formation GO:0001707 69 31 0,000 0,01228437 0,01595907 ! natural killer cell activation GO:0030101 45 31 0,000 0,01228437 0,01595046 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,01228437 0,01594185 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,01228437 0,01593326 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,01228437 0,01592468 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,01228437 0,0159161 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,01228437 0,01590753 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,01267833 0,01640885 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,01267833 0,01640003 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,01267833 0,01639122 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,01267833 0,01638242 ! cholesterol transport GO:0030301 56 32 0,000 0,01267833 0,01637362 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,01267833 0,01636484 ! spliceosome assembly GO:0000245 67 32 0,000 0,01267833 0,01635606 ! spindle organization GO:0007051 46 32 0,000 0,01267833 0,0163473 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,01267833 0,01633854 ! metanephros development GO:0001656 74 32 0,000 0,01267833 0,0163298 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,01267833 0,01632106 ! response to ionizing radiation GO:0010212 65 32 0,000 0,01267833 0,01631233 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,01267833 0,01630361 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,01267833 0,0162949 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,01267833 0,0162862 ! muscle cell development GO:0055001 49 32 0,000 0,01267833 0,01627751 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,01267833 0,01626883 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,01267833 0,01626016 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,01267833 0,0162515 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,01267833 0,01624284 ! ovulation cycle GO:0042698 51 32 0,000 0,01267833 0,0162342 ! peripheral nervous system development GO:0007422 64 32 0,000 0,01267833 0,01622556 ! BMP signaling pathway GO:0030509 64 32 0,000 0,01267833 0,01621694 ! hindbrain development GO:0030902 61 32 0,000 0,01267833 0,01620832 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,01267833 0,01619971 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,01267833 0,01619111 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,01267833 0,01618252 ! gene silencing GO:0016458 65 32 0,000 0,01267833 0,01617394 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,01307214 0,0166675 ! post-embryonic development GO:0009791 69 33 0,000 0,01307214 0,01665867 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,01307214 0,01664985 ! protein targeting to membrane GO:0006612 68 33 0,000 0,01307214 0,01664104 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,01307214 0,01663224 ! ceramide metabolic process GO:0006672 64 33 0,000 0,01307214 0,01662345 ! formation of primary germ layer GO:0001704 72 33 0,000 0,01307214 0,01661467 ! cell fate specification GO:0001708 52 33 0,000 0,01307214 0,0166059 ! sterol transport GO:0015918 57 33 0,000 0,01307214 0,01659714 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,01307214 0,01658838 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,01307214 0,01657964 ! adult locomotory behavior GO:0008344 59 33 0,000 0,01307214 0,0165709 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,01307214 0,01656218 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,01307214 0,01655346 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,01346581 0,017043 ! glial cell differentiation GO:0010001 63 34 0,000 0,01346581 0,01703404 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,01346581 0,01702509 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,01346581 0,01701614 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,01346581 0,01700721 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,01346581 0,01699829 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,01346581 0,01698938 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,01346581 0,01698047 ! mismatch repair GO:0006298 46 34 0,000 0,01346581 0,01697158 ! spermatid development GO:0007286 63 34 0,000 0,01346581 0,01696269 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,01346581 0,01695381 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,01346581 0,01694495 ! placenta development GO:0001890 53 34 0,000 0,01346581 0,01693609 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,01346581 0,01692724 ! regulation of muscle development GO:0048634 70 35 0,000 0,01385933 0,01741282 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,01385933 0,01740374 ! negative regulation of secretion GO:0051048 63 35 0,000 0,01385933 0,01739466 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,01385933 0,01738559 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,01385933 0,01737653 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,01385933 0,01736748 ! odontogenesis GO:0042476 66 35 0,000 0,01385933 0,01735844 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,01385933 0,01734941 ! female gonad development GO:0008585 58 35 0,000 0,01385933 0,01734038 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,01385933 0,01733137 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,01385933 0,01732237 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,01385933 0,01731337 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,01385933 0,01730439 ! cytokine production GO:0001816 59 35 0,000 0,01385933 0,01729541 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,01385933 0,01728645 ! neural tube formation GO:0001841 67 35 0,000 0,01385933 0,01727749 ! vesicle localization GO:0051648 64 35 0,000 0,01385933 0,01726854 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,01425272 0,0177495 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,01425272 0,01774032 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,01425272 0,01773114 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,01425272 0,01772198 ! cell junction organization GO:0034330 86 36 0,000 0,01425272 0,01771283 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,01425272 0,01770368 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,01425272 0,01769455 ! positive regulation of cell development GO:0010720 80 36 0,000 0,01425272 0,01768542 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,01425272 0,01767631 ! regulation of proteolysis GO:0030162 72 36 0,000 0,01425272 0,0176672 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,01425272 0,0176581 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,01425272 0,01764901 ! aerobic respiration GO:0009060 55 36 0,000 0,01425272 0,01763994 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,01425272 0,01763087 ! embryonic organ development GO:0048568 57 36 0,000 0,01425272 0,01762181 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,01425272 0,01761276 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,01425272 0,01760371 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,01464595 0,01808012 ! meiosis I GO:0007127 65 37 0,000 0,01464595 0,01807085 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,01464595 0,01806159 ! sister chromatid segregation GO:0000819 58 37 0,000 0,01464595 0,01805234 ! actomyosin structure organization GO:0031032 62 37 0,000 0,01464595 0,01804309 ! organic anion transport GO:0015711 68 37 0,000 0,01464595 0,01803386 ! tissue remodeling GO:0048771 76 37 0,000 0,01464595 0,01802464 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,01464595 0,01801542 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,01464595 0,01800622 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,01464595 0,01799702 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,01464595 0,01798783 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,01464595 0,01797865 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,01464595 0,01796949 ! glycogen metabolic process GO:0005977 61 37 0,000 0,01464595 0,01796033 ! pigment metabolic process GO:0042440 80 37 0,000 0,01464595 0,01795118 ! spermatid differentiation GO:0048515 66 37 0,000 0,01464595 0,01794204 ! cellular response to insulin stimulus GO:0032869 82 37 0,000 0,01464595 0,01793291 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,01503905 0,01840486 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,01503905 0,0183955 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,01503905 0,01838615 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,01503905 0,01837681 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,01503905 0,01836749 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,01503905 0,01835817 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,01503905 0,01834886 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,01503905 0,01833956 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,01503905 0,01833027 ! lipid homeostasis GO:0055088 67 38 0,000 0,01503905 0,01832099 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,01503905 0,01831171 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,01503905 0,01830245 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,01503905 0,0182932 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,01503905 0,01828395 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,01503905 0,01827472 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,01503905 0,0182655 ! glucan metabolic process GO:0044042 62 38 0,000 0,01503905 0,01825628 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,015432 0,01872384 ! mammary gland development GO:0030879 86 39 0,000 0,015432 0,01871441 ! learning GO:0007612 77 39 0,000 0,015432 0,01870498 ! ear morphogenesis GO:0042471 60 39 0,000 0,015432 0,01869556 ! organic ether metabolic process GO:0018904 55 39 0,000 0,015432 0,01868615 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,015432 0,01867675 ! segmentation GO:0035282 67 39 0,000 0,015432 0,01866736 ! ion transmembrane transport GO:0034220 66 39 0,000 0,015432 0,01865798 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,015432 0,01864861 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,015432 0,01863925 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,015432 0,0186299 ! RNA modification GO:0009451 57 39 0,000 0,015432 0,01862055 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,015432 0,01861122 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,0158248 0,01907539 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,0158248 0,01906584 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,0158248 0,01905629 ! feeding behavior GO:0007631 59 40 0,000 0,0158248 0,01904676 ! negative regulation of binding GO:0051100 72 40 0,000 0,0158248 0,01903724 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,0158248 0,01902772 ! mesenchymal cell development GO:0014031 87 40 0,000 0,0158248 0,01901822 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,0158248 0,01900872 ! maintenance of protein location GO:0045185 91 40 0,000 0,0158248 0,01899924 ! cytokinesis GO:0000910 72 40 0,000 0,0158248 0,01898976 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,01621746 0,01945126 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,01621746 0,01944156 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,01621746 0,01943188 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,01621746 0,01942221 ! gliogenesis GO:0042063 88 41 0,000 0,01621746 0,01941255 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,01621746 0,01940289 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,01621746 0,01939325 ! T cell differentiation GO:0030217 81 41 0,000 0,01621746 0,01938362 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,01621746 0,01937399 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,01621746 0,01936438 ! female gamete generation GO:0007292 61 41 0,000 0,01621746 0,01935477 ! polyol metabolic process GO:0019751 66 41 0,000 0,01621746 0,01934518 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,01621746 0,01933559 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,01660998 0,01979377 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,01660998 0,01978397 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,01660998 0,01977418 ! regulation of tube size GO:0035150 71 42 0,000 0,01660998 0,0197644 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,01660998 0,01975463 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,01660998 0,01974487 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,01660998 0,01973512 ! regulation of intracellular protein transport GO:0033157 80 42 0,000 0,01660998 0,01972538 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,01660998 0,01971565 ! neuron migration GO:0001764 79 42 0,000 0,01660998 0,01970593 ! regulation of protein secretion GO:0050708 71 42 0,000 0,01660998 0,01969621 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,01660998 0,01968651 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,01700236 0,02014164 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,01700236 0,02013173 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,01700236 0,02012183 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,01700236 0,02011193 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,01700236 0,02010205 ! glucose transport GO:0015758 65 43 0,000 0,01700236 0,02009218 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,01700236 0,02008231 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,01700236 0,02007246 ! neural tube development GO:0021915 77 43 0,000 0,01700236 0,02006262 ! regulation of epithelial cell proliferation GO:0050678 111 43 0,000 0,01700236 0,02005278 ! striated muscle contraction GO:0006941 77 43 0,000 0,01700236 0,02004296 ! phagocytosis GO:0006909 90 43 0,000 0,01700236 0,02003314 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,01700236 0,02002333 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,01739459 0,02047524 ! hexose transport GO:0008645 67 44 0,000 0,01739459 0,02046522 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,01739459 0,02045522 ! male sex differentiation GO:0046661 76 44 0,000 0,01739459 0,02044523 ! double-strand break repair GO:0006302 81 44 0,000 0,01739459 0,02043525 ! biopolymer methylation GO:0043414 84 44 0,000 0,01739459 0,02042527 ! B cell differentiation GO:0030183 107 44 0,000 0,01739459 0,02041531 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,01739459 0,02040535 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,01739459 0,02039541 ! developmental growth GO:0048589 82 44 0,000 0,01739459 0,02038548 ! maintenance of location in cell GO:0051651 97 44 0,000 0,01739459 0,02037555 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,01778668 0,02082469 ! glycolysis GO:0006096 65 45 0,000 0,01778668 0,02081457 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,01778668 0,02080445 ! leukocyte migration GO:0050900 68 45 0,000 0,01778668 0,02079434 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,01778668 0,02078424 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,01778668 0,02077415 ! induction of apoptosis by intracellular signals GO:0008629 93 45 0,000 0,01778668 0,02076407 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,01778668 0,020754 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,01778668 0,02074394 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,01778668 0,02073389 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,01778668 0,02072385 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,01778668 0,02071382 ! cell growth GO:0016049 84 45 0,000 0,01778668 0,0207038 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,01817862 0,02114979 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 0,000 0,01817862 0,02113957 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,01817862 0,02112936 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,01817862 0,02111915 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,01817862 0,02110896 ! pigmentation GO:0043473 100 46 0,000 0,01817862 0,02109878 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,01817862 0,0210886 ! positive regulation of defense response GO:0031349 76 47 0,000 0,01857042 0,02153274 ! endosome transport GO:0016197 108 47 0,000 0,01857042 0,02152237 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,01857042 0,02151201 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,01857042 0,02150165 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,01857042 0,02149131 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,01857042 0,02148098 ! JNK cascade GO:0007254 91 47 0,000 0,01857042 0,02147066 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,01857042 0,02146035 ! methylation GO:0032259 90 47 0,000 0,01857042 0,02145004 ! protein homooligomerization GO:0051260 76 47 0,000 0,01857042 0,02143975 ! mitochondrial transport GO:0006839 82 48 0,000 0,01896208 0,02188142 ! Notch signaling pathway GO:0007219 96 48 0,000 0,01896208 0,02187093 ! cellular component disassembly GO:0022411 86 48 0,000 0,01896208 0,02186045 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,01896208 0,02184998 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,01896208 0,02183953 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,01896208 0,02182908 ! activation of caspase activity GO:0006919 84 48 0,000 0,01896208 0,02181864 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,01896208 0,02180821 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,01896208 0,02179779 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,01896208 0,02178738 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,01896208 0,02177698 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,0193536 0,02221601 ! regulation of action potential GO:0001508 95 49 0,000 0,0193536 0,02220541 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,0193536 0,02219483 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,0193536 0,02218426 ! regulation of ion transport GO:0043269 77 49 0,000 0,0193536 0,02217369 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,0193536 0,02216314 ! peptide metabolic process GO:0006518 76 49 0,000 0,0193536 0,02215259 ! response to temperature stimulus GO:0009266 76 49 0,000 0,0193536 0,02214206 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,0193536 0,02213154 ! endocrine system development GO:0035270 104 49 0,000 0,0193536 0,02212102 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,0193536 0,02211052 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,0193536 0,02210002 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,0193536 0,02208954 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,0193536 0,02207907 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,01974497 0,02251488 ! neuromuscular process GO:0050905 99 50 0,000 0,01974497 0,02250421 ! regulation of ossification GO:0030278 117 50 0,000 0,01974497 0,02249356 ! inner ear development GO:0048839 79 50 0,000 0,01974497 0,02248291 ! histone modification GO:0016570 91 50 0,000 0,01974497 0,02247228 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,01974497 0,02246165 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,01974497 0,02245104 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,01974497 0,02244043 ! positive regulation of binding GO:0051099 78 51 0,000 0,0201362 0,02287426 ! viral infectious cycle GO:0019058 99 51 0,000 0,0201362 0,02286347 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,0201362 0,02285268 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,0201362 0,02284191 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,0201362 0,02283114 ! excretion GO:0007588 83 51 0,000 0,0201362 0,02282039 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,0201362 0,02280965 ! chromatin remodeling GO:0006338 109 51 0,000 0,0201362 0,02279891 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,0201362 0,02278819 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,0201362 0,02277747 ! vesicle organization GO:0016050 107 51 0,000 0,0201362 0,02276677 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,0201362 0,02275608 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 0,000 0,0201362 0,02274539 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,0201362 0,02273472 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,02052728 0,0231654 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,02052728 0,02315454 ! membrane fusion GO:0006944 110 52 0,000 0,02052728 0,02314369 ! positive regulation of growth GO:0045927 90 52 0,000 0,02052728 0,02313285 ! covalent chromatin modification GO:0016569 101 52 0,000 0,02052728 0,02312202 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,02052728 0,0231112 ! amino acid activation GO:0043038 92 52 0,000 0,02052728 0,02310039 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,02052728 0,02308959 ! synapse organization GO:0050808 85 52 0,000 0,02052728 0,0230788 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,02091822 0,02350735 ! RNA catabolic process GO:0006401 93 53 0,000 0,02091822 0,02349638 ! regulation of translational initiation GO:0006446 82 53 0,000 0,02091822 0,02348542 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,02091822 0,02347446 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,02091822 0,02346352 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,02091822 0,02345258 ! cell maturation GO:0048469 100 53 0,000 0,02091822 0,02344166 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,02091822 0,02343075 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,02091822 0,02341984 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,02130902 0,02384628 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,02130902 0,0238352 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,02130902 0,02382412 ! cell recognition GO:0008037 85 54 0,000 0,02130902 0,02381305 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,02130902 0,023802 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,02130902 0,02379095 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,02130902 0,02377992 ! chloride transport GO:0006821 90 55 0,000 0,02169968 0,02420465 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,02169968 0,02419343 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,02169968 0,02418223 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,02169968 0,02417103 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,02169968 0,02415985 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,02169968 0,02414867 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,02169968 0,02413751 ! aging GO:0007568 103 55 0,000 0,02169968 0,02412635 ! gastrulation GO:0007369 112 55 0,000 0,02169968 0,02411521 ! heart morphogenesis GO:0003007 97 55 0,000 0,02169968 0,02410407 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,02169968 0,02409295 ! RNA elongation GO:0006354 79 55 0,000 0,02169968 0,02408184 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,02169968 0,02407074 ! regulation of actin filament length GO:0030832 105 56 0,000 0,02209019 0,02449263 ! sensory perception of smell GO:0007608 80 56 0,000 0,02209019 0,02448134 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,02209019 0,02447007 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,02209019 0,02445881 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,02209019 0,02444756 ! regulation of DNA replication GO:0006275 101 56 0,000 0,02209019 0,02443632 ! proton transport GO:0015992 94 56 0,000 0,02209019 0,02442509 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,02209019 0,02441387 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,02248056 0,0248339 ! muscle fiber development GO:0048747 112 57 0,000 0,02248056 0,0248225 ! positive regulation of cell migration GO:0030335 126 57 0,000 0,02248056 0,02481111 ! lipid modification GO:0030258 97 57 0,000 0,02248056 0,02479974 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,02248056 0,02478837 ! regulation of intracellular transport GO:0032386 101 57 0,000 0,02248056 0,02477702 ! maintenance of location GO:0051235 118 57 0,000 0,02248056 0,02476567 ! hydrogen transport GO:0006818 97 58 0,000 0,02287079 0,02518404 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,02287079 0,02517251 ! regulation of endocytosis GO:0030100 91 58 0,000 0,02287079 0,025161 ! adult behavior GO:0030534 99 58 0,000 0,02287079 0,02514951 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,02287079 0,02513802 ! positive regulation of secretion GO:0051047 95 59 0,000 0,02326087 0,0255551 ! regulation of cellular component size GO:0032535 109 59 0,000 0,02326087 0,02554343 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,02326087 0,02553178 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,02326087 0,02552014 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,02326087 0,02550851 ! DNA catabolic process GO:0006308 86 59 0,000 0,02326087 0,02549688 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,02326087 0,02548527 ! establishment of organelle localization GO:0051656 109 59 0,000 0,02326087 0,02547367 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,02365081 0,02588893 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,02365081 0,02587715 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,02365081 0,02586539 ! regulation of heart contraction GO:0008016 110 60 0,000 0,02365081 0,02585364 ! camera-type eye development GO:0043010 116 60 0,000 0,02365081 0,0258419 ! protein amino acid autophosphorylation GO:0046777 141 60 0,000 0,02365081 0,02583017 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,02365081 0,02581845 ! kidney development GO:0001822 122 60 0,000 0,02365081 0,02580674 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,02404061 0,02622018 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,02404061 0,0262083 ! mesoderm development GO:0007498 119 61 0,000 0,02404061 0,02619643 ! tRNA processing GO:0008033 89 61 0,000 0,02404061 0,02618457 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,02404061 0,02617272 ! ear development GO:0043583 103 62 0,000 0,02443027 0,02658491 ! viral reproductive process GO:0022415 126 62 0,000 0,02443027 0,02657289 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,02443027 0,02656088 ! gonad development GO:0008406 98 62 0,000 0,02443027 0,02654888 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,02443027 0,0265369 ! regulation of mitosis GO:0007088 105 63 0,000 0,02481978 0,02694783 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,02481978 0,02693568 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,02481978 0,02692353 ! detection of external stimulus GO:0009581 91 63 0,000 0,02481978 0,0269114 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,02481978 0,02689928 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,02481978 0,02688717 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,02520916 0,02729668 ! cell redox homeostasis GO:0045454 102 64 0,000 0,02520916 0,0272844 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,02520916 0,02727213 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,02520916 0,02725988 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,02520916 0,02724763 ! positive regulation of cell motion GO:0051272 146 64 0,000 0,02520916 0,0272354 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,02559838 0,0276435 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,02559838 0,0276311 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,02559838 0,0276187 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,02559838 0,02760633 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,02559838 0,02759396 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,02598747 0,02800083 ! actin filament organization GO:0007015 148 66 0,000 0,02598747 0,0279883 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,02598747 0,02797577 ! extracellular matrix organization GO:0030198 133 66 0,000 0,02598747 0,02796326 ! secondary metabolic process GO:0019748 116 66 0,000 0,02598747 0,02795076 ! developmental maturation GO:0021700 116 66 0,000 0,02598747 0,02793827 ! cell projection assembly GO:0030031 120 66 0,000 0,02598747 0,02792579 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,02637641 0,02833109 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,02637641 0,02831845 ! negative regulation of protein kinase activity GO:0006469 130 67 0,000 0,02637641 0,02830582 ! negative regulation of cell growth GO:0030308 132 67 0,000 0,02637641 0,0282932 ! activation of MAPK activity GO:0000187 115 67 0,000 0,02637641 0,02828059 ! lung development GO:0030324 144 67 0,000 0,02637641 0,028268 ! chromosome segregation GO:0007059 113 67 0,000 0,02637641 0,02825541 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,02637641 0,02824284 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,02637641 0,02823027 ! hexose catabolic process GO:0019320 104 67 0,000 0,02637641 0,02821772 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,02637641 0,02820518 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,02637641 0,02819265 ! adaptive immune response GO:0002250 119 67 0,000 0,02637641 0,02818013 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,02637641 0,02816762 ! amino acid transport GO:0006865 125 68 0,000 0,02676522 0,02857015 ! negative regulation of kinase activity GO:0033673 131 68 0,000 0,02676522 0,02855748 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,02676522 0,02854482 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,02676522 0,02853217 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,02676522 0,02851953 ! viral reproduction GO:0016032 134 68 0,000 0,02676522 0,02850691 ! regulation of lipase activity GO:0060191 130 68 0,000 0,02676522 0,0284943 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,02676522 0,02848169 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,02715387 0,0288825 ! negative regulation of cell size GO:0045792 134 69 0,000 0,02715387 0,02886974 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,02715387 0,02885699 ! urogenital system development GO:0001655 137 69 0,000 0,02715387 0,02884425 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,02715387 0,02883152 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,02715387 0,0288188 ! antigen processing and presentation GO:0019882 104 69 0,000 0,02715387 0,02880609 ! appendage morphogenesis GO:0035107 135 70 0,000 0,02754239 0,02920537 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 0,000 0,02754239 0,02919251 ! amine catabolic process GO:0009310 117 71 0,000 0,02793077 0,02959112 ! reproductive structure development GO:0048608 113 71 0,000 0,02793077 0,02957809 ! appendage development GO:0048736 136 71 0,000 0,02793077 0,02956508 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,02793077 0,02955208 ! B cell activation GO:0042113 160 71 0,000 0,02793077 0,02953909 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,02793077 0,02952611 ! regulation of immune effector process GO:0002697 137 71 0,000 0,02793077 0,02951314 ! acute inflammatory response GO:0002526 113 72 0,000 0,028319 0,02991023 ! regulation of caspase activity GO:0043281 122 72 0,000 0,028319 0,02989711 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,028319 0,029884 ! carbohydrate transport GO:0008643 110 72 0,000 0,028319 0,02987089 ! negative regulation of transferase activity GO:0051348 140 72 0,000 0,028319 0,0298578 ! respiratory system development GO:0060541 153 72 0,000 0,028319 0,02984473 ! learning or memory GO:0007611 147 73 0,000 0,02870709 0,03024048 ! regulation of blood pressure GO:0008217 125 73 0,000 0,02870709 0,03022725 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,02870709 0,03021402 ! axon guidance GO:0007411 139 73 0,000 0,02870709 0,03020081 ! fertilization GO:0009566 90 73 0,000 0,02870709 0,03018761 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,02909504 0,0305822 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,02909504 0,03056885 ! neurotransmitter transport GO:0006836 123 74 0,000 0,02909504 0,0305555 ! meiosis GO:0007126 121 74 0,000 0,02909504 0,03054217 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,02909504 0,03052885 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,02909504 0,03051554 ! regulation of endopeptidase activity GO:0052548 125 74 0,000 0,02909504 0,03050225 ! eye development GO:0001654 143 74 0,000 0,02909504 0,03048896 ! organelle localization GO:0051640 136 74 0,000 0,02909504 0,03047569 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,02948284 0,03086846 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,02948284 0,03085503 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,02948284 0,03084162 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,02948284 0,03082821 ! meiotic cell cycle GO:0051321 122 75 0,000 0,02948284 0,03081482 ! rhythmic process GO:0048511 128 75 0,000 0,02948284 0,03080144 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,02948284 0,03078807 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,02987051 0,03117937 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,02987051 0,03116585 ! defense response to bacterium GO:0042742 89 76 0,000 0,02987051 0,03115234 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,02987051 0,03113884 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,02987051 0,03112535 ! regulation of catabolic process GO:0009894 161 76 0,000 0,02987051 0,03111188 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,03025803 0,03150187 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,03025803 0,03148824 ! blood coagulation GO:0007596 146 78 0,000 0,03064541 0,03187759 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,03064541 0,03186381 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,03064541 0,03185005 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,03064541 0,03183629 ! protein oligomerization GO:0051259 139 78 0,000 0,03064541 0,03182255 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,03103265 0,03221076 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,03103265 0,03219687 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,03103265 0,032183 ! regulation of peptidase activity GO:0052547 134 79 0,000 0,03103265 0,03216913 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,03103265 0,03215528 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,03141974 0,03254236 ! muscle cell differentiation GO:0042692 159 80 0,000 0,03141974 0,03252836 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,03141974 0,03251437 ! protein import into nucleus GO:0006606 158 80 0,000 0,03141974 0,03250039 ! inorganic anion transport GO:0015698 138 80 0,000 0,03141974 0,03248642 ! T cell activation GO:0042110 168 81 0,000 0,0318067 0,03287239 ! response to hypoxia GO:0001666 171 81 0,000 0,0318067 0,03285827 ! digestion GO:0007586 112 81 0,000 0,0318067 0,03284417 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,0318067 0,03283008 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,0318067 0,032816 ! nuclear import GO:0051170 161 81 0,000 0,0318067 0,03280194 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,0318067 0,03278788 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,03219351 0,03317242 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,03219351 0,03315822 ! response to drug GO:0042493 143 82 0,000 0,03219351 0,03314403 ! response to nutrient GO:0007584 125 82 0,000 0,03219351 0,03312985 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,03219351 0,03311569 ! cellular response to hormone stimulus GO:0032870 167 82 0,000 0,03219351 0,03310153 ! response to oxygen levels GO:0070482 176 83 0,000 0,03258018 0,0334848 ! regulation of lyase activity GO:0051339 160 83 0,000 0,03258018 0,03347051 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,03296671 0,03385314 ! hemostasis GO:0007599 158 84 0,000 0,03296671 0,0338387 ! negative regulation of transport GO:0051051 153 84 0,000 0,03296671 0,03382427 ! negative regulation of growth GO:0045926 155 84 0,000 0,03296671 0,03380985 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,03296671 0,03379545 ! nucleosome assembly GO:0006334 122 85 0,000 0,0333531 0,03417699 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,0333531 0,03416244 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,0333531 0,0341479 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,03373935 0,03452866 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,03373935 0,03451398 ! chromatin assembly GO:0031497 124 86 0,000 0,03373935 0,03449931 ! tube morphogenesis GO:0035239 176 86 0,000 0,03373935 0,03448465 ! mitochondrion organization GO:0007005 148 86 0,000 0,03373935 0,03447001 ! alcohol catabolic process GO:0046164 130 86 0,000 0,03373935 0,03445538 ! amine transport GO:0015837 155 86 0,000 0,03373935 0,03444076 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,03412545 0,03482012 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,03412545 0,03480536 ! protein localization in nucleus GO:0034504 176 87 0,000 0,03412545 0,03479061 ! regulation of protein transport GO:0051223 154 87 0,000 0,03412545 0,03477588 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 135 88 0,000 0,03451142 0,03515431 ! regulation of DNA binding GO:0051101 155 88 0,000 0,03451142 0,03513943 ! gland development GO:0048732 206 88 0,000 0,03451142 0,03512457 ! regulation of neurological system process GO:0031644 148 88 0,000 0,03451142 0,03510971 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,03451142 0,03509487 ! cellular defense response GO:0006968 114 89 0,000 0,03489724 0,03547223 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,03489724 0,03545725 ! ossification GO:0001503 188 90 0,000 0,03528292 0,03583398 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,03528292 0,03581886 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,03528292 0,03580376 ! sex differentiation GO:0007548 145 90 0,000 0,03528292 0,03578866 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,03528292 0,03577358 ! bone development GO:0060348 189 91 0,000 0,03566846 0,03614925 ! sterol metabolic process GO:0016125 152 91 0,000 0,03566846 0,03613403 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,03566846 0,03611882 ! regulation of defense response GO:0031347 149 92 0,000 0,03605386 0,03649373 ! nucleosome organization GO:0034728 138 92 0,000 0,03605386 0,03647838 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,03605386 0,03646305 ! vitamin metabolic process GO:0006766 139 92 0,000 0,03605386 0,03644773 ! positive regulation of MAP kinase activity GO:0043406 160 93 0,000 0,03643912 0,03682172 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,03643912 0,03680626 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,03643912 0,03679082 ! regulation of membrane potential GO:0042391 164 93 0,000 0,03643912 0,03677538 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,03643912 0,03675997 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,03682423 0,0371329 ! female pregnancy GO:0007565 164 94 0,000 0,03682423 0,03711735 ! transcription initiation GO:0006352 153 94 0,000 0,03682423 0,0371018 ! regulation of T cell activation GO:0050863 158 94 0,000 0,03682423 0,03708627 ! forebrain development GO:0030900 188 95 0,000 0,03720921 0,03745831 ! leukocyte differentiation GO:0002521 202 96 0,000 0,03759404 0,03782989 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,03759404 0,03781408 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,03759404 0,03779827 ! positive regulation of immune response GO:0050778 156 96 0,000 0,03759404 0,03778248 ! detection of stimulus GO:0051606 151 96 0,000 0,03759404 0,03776671 ! regulation of DNA metabolic process GO:0051052 178 97 0,000 0,03797874 0,03813725 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,03797874 0,03812133 ! protein ubiquitination GO:0016567 217 97 0,000 0,03797874 0,03810544 ! hormone metabolic process GO:0042445 157 97 0,000 0,03797874 0,03808955 ! regulation of protein localization GO:0032880 176 97 0,000 0,03797874 0,03807368 ! response to virus GO:0009615 160 98 0,000 0,03836329 0,03844318 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,03836329 0,03842717 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,03836329 0,03841118 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,0387477 0,03877994 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,0387477 0,03876381 ! skeletal muscle tissue development GO:0007519 186 99 0,000 0,0387477 0,0387477 GO:0060538|skeletal muscle organ development,