pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-b1/out-0.05-06-0.01-300-run-b1//th1-pval-1e-01-08-th2-pval-1e-02-02-th3-pval-1e-01-01-run-b1/go_data/22907-2-real-Zhang-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! positive regulation of cell cycle GO:0045787 77 45 2,000 2,052E-05 0,04719789 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 2,876E-05 0,03307007 ! histone deacetylation GO:0016575 13 11 1,000 7,51E-05 0,05757426 ! negative regulation of cell cycle process GO:0010948 24 15 1,000 1,43E-04 0,0821973 ! protein amino acid deacetylation GO:0006476 20 16 1,000 1,633E-04 0,07509739 ! cellular response to unfolded protein GO:0034620 19 16 1,000 1,633E-04 0,06258116 GO:0030968|endoplasmic reticulum unfolded protein response, ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 1,000 1,633E-04 0,053641 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 1,000 2,078E-04 0,0597566 ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 2,847E-04 0,07274741 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 3,425E-04 0,07876481 ! fat cell differentiation GO:0045444 37 24 1,000 3,733E-04 0,07805731 ! base-excision repair GO:0006284 31 24 1,000 3,733E-04 0,07155253 ! regulation of chromosome organization GO:0033044 35 25 1,000 4,055E-04 0,07173987 ! positive regulation of nuclear division GO:0051785 39 25 1,000 4,055E-04 0,0666156 GO:0045840|positive regulation of mitosis, ! spindle organization GO:0007051 37 30 1,000 5,858E-04 0,08982733 ! mitotic sister chromatid segregation GO:0000070 45 32 1,000 6,67E-04 0,09588339 ! meiosis I GO:0007127 52 32 1,000 6,67E-04 0,0902432 ! sister chromatid segregation GO:0000819 46 33 1,000 7,095E-04 0,09066272 ! cytokinesis GO:0000910 52 33 1,000 7,095E-04 0,085891 ! response to calcium ion GO:0051592 58 40 1,000 1,043E-03 0,1199311 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 1,000 1,205E-03 0,13194502 ! regulation of translational initiation GO:0006446 64 45 1,000 1,319E-03 0,13788235 ! histone modification GO:0016570 68 46 1,000 1,378E-03 0,13778264 ! response to UV GO:0009411 75 46 1,000 1,378E-03 0,1320417 ! covalent chromatin modification GO:0016569 75 47 1,000 1,438E-03 0,13229808 ! regulation of DNA replication GO:0006275 75 48 1,000 1,499E-03 0,13264456 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 1,000 1,691E-03 0,14406478 ! positive regulation of organelle organization GO:0010638 82 51 1,000 1,691E-03 0,13891961 ! nucleotide-excision repair GO:0006289 64 52 1,000 1,758E-03 0,1393936 ! establishment of organelle localization GO:0051656 85 52 1,000 1,758E-03 0,13474715 ! regulation of mitosis GO:0007088 84 54 1,000 1,894E-03 0,14052292 GO:0051783|regulation of nuclear division, ! chromosome segregation GO:0007059 83 57 1,000 2,108E-03 0,15149912 ! meiosis GO:0007126 96 61 1,000 2,41E-03 0,16796102 GO:0051327|M phase of meiotic cell cycle, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 1,000 2,41E-03 0,16302099 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 1,000 2,488E-03 0,16352378 ! meiotic cell cycle GO:0051321 97 62 1,000 2,488E-03 0,15898146 ! organelle localization GO:0051640 96 62 1,000 2,488E-03 0,15468466 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 1,000 2,649E-03 0,16033805 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 1,000 2,731E-03 0,16106995 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 1,000 2,731E-03 0,1570432 ! positive regulation of ligase activity GO:0051351 99 69 1,000 3,072E-03 0,17230767 ! response to metal ion GO:0010038 103 70 1,000 3,16E-03 0,17302725 ! positive regulation of phosphorylation GO:0042327 102 70 1,000 3,16E-03 0,16900336 ! phosphoinositide-mediated signaling GO:0048015 109 71 1,000 3,249E-03 0,16982695 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 1,000 3,249E-03 0,16605301 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 1,000 3,339E-03 0,16696373 GO:0045937|positive regulation of phosphate metabolic process, ! negative regulation of organelle organization GO:0010639 115 72 1,000 3,339E-03 0,16341131 ! regulation of ligase activity GO:0051340 114 75 1,000 3,618E-03 0,17334035 ! response to inorganic substance GO:0010035 115 75 1,000 3,618E-03 0,1698028 ! response to unfolded protein GO:0006986 99 76 1,000 3,713E-03 0,17078082 ! positive regulation of protein modification process GO:0031401 107 78 1,000 3,906E-03 0,17616598 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 1,000 4,105E-03 0,18154878 GO:0010498|proteasomal protein catabolic process, ! regulation of cell cycle process GO:0010564 122 81 1,000 4,205E-03 0,18250094 ! response to protein stimulus GO:0051789 111 81 1,000 4,205E-03 0,1791213 ! microtubule cytoskeleton organization GO:0000226 120 84 1,000 4,515E-03 0,18880778 ! regulation of DNA metabolic process GO:0051052 135 85 1,000 4,62E-03 0,1897675 ! interphase of mitotic cell cycle GO:0051329 156 86 1,000 4,727E-03 0,1907395 ! interphase GO:0051325 159 88 1,000 4,944E-03 0,19604014 ! response to light stimulus GO:0009416 153 96 1,000 5,855E-03 0,22824769 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 5,992E-03 0,22971056 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 5,992E-03 0,22594481 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 5,992E-03 0,22230054 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 5,992E-03 0,21877196 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 5,992E-03 0,21535365 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 5,992E-03 0,21204052 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 5,992E-03 0,20882778 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 5,992E-03 0,20571095 ! sleep GO:0030431 11 5 0,000 5,992E-03 0,20268579 ! negative regulation of bone resorption GO:0045779 10 5 0,000 5,992E-03 0,19974831 ! nucleotide-sugar transport GO:0015780 8 5 0,000 5,992E-03 0,19689477 ! regulation of interferon-beta production GO:0032648 5 5 0,000 5,992E-03 0,1941216 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 5,992E-03 0,19142547 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 5,992E-03 0,1888032 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 5,992E-03 0,18625181 ! tongue development GO:0043586 6 5 0,000 5,992E-03 0,18376845 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 5,992E-03 0,18135044 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 5,992E-03 0,17899524 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 5,992E-03 0,17670043 ! cobalt ion transport GO:0006824 9 5 0,000 5,992E-03 0,17446372 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 5,992E-03 0,17228292 ! SMAD protein complex assembly GO:0007183 9 5 0,000 5,992E-03 0,17015597 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 5,992E-03 0,1680809 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 5,992E-03 0,16605583 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 5,992E-03 0,16407897 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 5,992E-03 0,16214863 ! embryonic camera-type eye development GO:0031076 8 5 0,000 5,992E-03 0,16026318 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 5,992E-03 0,15842108 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 5,992E-03 0,15662084 ! adaptation of signaling pathway GO:0022401 7 5 0,000 5,992E-03 0,15486105 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 5,992E-03 0,15314037 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 5,992E-03 0,15145751 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 5,992E-03 0,14981123 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 5,992E-03 0,14820036 ! positive regulation of histone modification GO:0031058 5 5 0,000 5,992E-03 0,14662376 ! malate metabolic process GO:0006108 7 5 0,000 5,992E-03 0,14508035 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 5,992E-03 0,1435691 ! behavioral response to pain GO:0048266 7 5 0,000 5,992E-03 0,14208901 ! clathrin coat assembly GO:0048268 11 5 0,000 5,992E-03 0,14063912 ! phototransduction, visible light GO:0007603 6 5 0,000 5,992E-03 0,13921852 ! regulation of dopamine uptake GO:0051584 9 5 0,000 5,992E-03 0,13782634 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 5,992E-03 0,13646172 ! mating behavior GO:0007617 6 5 0,000 5,992E-03 0,13512386 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 5,992E-03 0,13381198 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 5,992E-03 0,13252532 ! rhythmic behavior GO:0007622 12 5 0,000 5,992E-03 0,13126318 ! copulation GO:0007620 7 5 0,000 5,992E-03 0,13002485 ! glial cell fate commitment GO:0021781 12 5 0,000 5,992E-03 0,12880966 ! protein maturation by protein folding GO:0022417 12 5 0,000 5,992E-03 0,12761698 ! embryonic hemopoiesis GO:0035162 10 5 0,000 5,992E-03 0,12644618 ! regulation of potassium ion transport GO:0043266 9 5 0,000 5,992E-03 0,12529667 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 5,992E-03 0,12416787 ! apoptotic cell clearance GO:0043277 13 5 0,000 5,992E-03 0,12305923 ! lipoprotein particle clearance GO:0034381 9 5 0,000 5,992E-03 0,12197021 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 5,992E-03 0,12090029 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 5,992E-03 0,11984899 ! response to protozoan GO:0001562 9 5 0,000 5,992E-03 0,11881581 ! positive regulation of glycolysis GO:0045821 11 5 0,000 5,992E-03 0,11780029 ! lymph vessel development GO:0001945 7 5 0,000 5,992E-03 0,11680198 ! endochondral ossification GO:0001958 12 5 0,000 5,992E-03 0,11582045 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 5,992E-03 0,11485528 ! parathyroid gland development GO:0060017 8 5 0,000 5,992E-03 0,11390606 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 5,992E-03 0,11297241 ! anagen GO:0042640 6 5 0,000 5,992E-03 0,11205393 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 5,992E-03 0,11115027 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 5,992E-03 0,11026107 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 5,992E-03 0,10938598 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 5,992E-03 0,10852467 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 5,992E-03 0,10767682 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 5,992E-03 0,10684212 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 5,992E-03 0,10602026 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 5,992E-03 0,10521094 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 5,992E-03 0,10441389 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 5,992E-03 0,10362882 ! cardiac muscle fiber development GO:0048739 7 5 0,000 5,992E-03 0,10285547 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 5,992E-03 0,10209358 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 5,992E-03 0,10134289 ! neutrophil mediated immunity GO:0002446 6 5 0,000 5,992E-03 0,10060316 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 5,992E-03 0,09987416 ! ovulation GO:0030728 6 5 0,000 5,992E-03 0,09915564 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 5,992E-03 0,09844738 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 5,992E-03 0,09774917 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 5,992E-03 0,0970608 ! response to pH GO:0009268 9 5 0,000 5,992E-03 0,09638205 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 5,992E-03 0,09571273 ! proline biosynthetic process GO:0006561 6 5 0,000 5,992E-03 0,09505265 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 5,992E-03 0,0944016 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 5,992E-03 0,09375941 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 5,992E-03 0,0931259 ! polyol catabolic process GO:0046174 7 5 0,000 5,992E-03 0,0925009 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 5,992E-03 0,09188422 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 5,992E-03 0,09127572 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 5,992E-03 0,09067522 ! sister chromatid cohesion GO:0007062 9 5 0,000 5,992E-03 0,09008257 ! nerve growth factor processing GO:0032455 7 5 0,000 5,992E-03 0,08949762 ! urea metabolic process GO:0019627 6 5 0,000 5,992E-03 0,08892022 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 5,992E-03 0,08835022 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 5,992E-03 0,08778748 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 5,992E-03 0,08723186 ! neutrophil activation GO:0042119 5 5 0,000 5,992E-03 0,08668323 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 5,992E-03 0,08614146 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 5,992E-03 0,08560642 ! response to food GO:0032094 5 5 0,000 5,992E-03 0,08507799 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 5,992E-03 0,08455603 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 5,992E-03 0,08404045 ! paraxial mesoderm development GO:0048339 9 5 0,000 5,992E-03 0,08353111 ! forebrain neuron development GO:0021884 7 5 0,000 5,992E-03 0,08302791 ! melanosome organization GO:0032438 7 5 0,000 5,992E-03 0,08253074 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 5,992E-03 0,08203949 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 5,992E-03 0,08155404 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 5,992E-03 0,08107432 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 5,992E-03 0,0806002 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 5,992E-03 0,08013159 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 5,992E-03 0,0796684 ! nucleoside transport GO:0015858 6 5 0,000 5,992E-03 0,07921054 ! nucleoside salvage GO:0043174 7 5 0,000 5,992E-03 0,07875791 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 5,992E-03 0,07831042 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 5,992E-03 0,07786799 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 5,992E-03 0,07743053 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 5,992E-03 0,07699795 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 5,992E-03 0,07657019 ! early endosome to late endosome transport GO:0045022 11 5 0,000 5,992E-03 0,07614715 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 5,992E-03 0,07572876 ! depyrimidination GO:0045008 8 5 0,000 5,992E-03 0,07531494 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 5,992E-03 0,07490562 ! 5S class rRNA transcription GO:0042791 8 5 0,000 5,992E-03 0,07450072 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 5,992E-03 0,07410018 ! regulation of centrosome cycle GO:0046605 7 5 0,000 5,992E-03 0,07370392 ! neuronal ion channel clustering GO:0045161 7 5 0,000 5,992E-03 0,07331188 ! sodium ion homeostasis GO:0055078 6 5 0,000 5,992E-03 0,07292399 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 5,992E-03 0,07254018 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 5,992E-03 0,07216039 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 5,992E-03 0,07178455 ! monocyte differentiation GO:0030224 8 5 0,000 5,992E-03 0,07141261 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 5,992E-03 0,0710445 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 5,992E-03 0,07068017 ! centrosome duplication GO:0051298 5 5 0,000 5,992E-03 0,07031956 ! response to UV-C GO:0010225 6 5 0,000 5,992E-03 0,06996261 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 5,992E-03 0,06960926 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 5,992E-03 0,06925947 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 5,992E-03 0,06891317 ! regulation of dendrite development GO:0050773 12 5 0,000 5,992E-03 0,06857032 ! peptidyl-arginine modification GO:0018195 7 5 0,000 5,992E-03 0,06823086 ! positive regulation of organ growth GO:0046622 6 5 0,000 5,992E-03 0,06789475 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 5,992E-03 0,06756193 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 5,992E-03 0,06723236 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 5,992E-03 0,06690599 ! regulation of dopamine secretion GO:0014059 12 5 0,000 5,992E-03 0,06658277 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 5,992E-03 0,06626266 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 5,992E-03 0,06594562 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 5,992E-03 0,06563159 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 5,992E-03 0,06532054 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 5,992E-03 0,06501242 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 5,992E-03 0,0647072 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 5,992E-03 0,06440483 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 5,992E-03 0,06410527 ! neural tube patterning GO:0021532 6 5 0,000 5,992E-03 0,06380849 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 5,992E-03 0,06351444 ! histone demethylation GO:0016577 9 5 0,000 5,992E-03 0,06322309 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 5,992E-03 0,0629344 ! regulation of sterol transport GO:0032371 7 5 0,000 5,992E-03 0,06264833 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 5,992E-03 0,06236486 ! enteric nervous system development GO:0048484 8 5 0,000 5,992E-03 0,06208394 ! establishment of planar polarity GO:0001736 6 5 0,000 5,992E-03 0,06180553 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 5,992E-03 0,06152961 ! muscle cell proliferation GO:0033002 8 5 0,000 5,992E-03 0,06125615 ! transcription termination GO:0006353 8 5 0,000 5,992E-03 0,0609851 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 5,992E-03 0,06071645 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 5,992E-03 0,06045015 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 5,992E-03 0,06018617 ! regulation of respiratory burst GO:0060263 8 5 0,000 5,992E-03 0,05992449 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 5,992E-03 0,05966508 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 5,992E-03 0,0594079 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 5,992E-03 0,05915293 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 5,992E-03 0,05890014 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 5,992E-03 0,0586495 ! apical protein localization GO:0045176 6 5 0,000 5,992E-03 0,05840099 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 5,992E-03 0,05815457 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 5,992E-03 0,05791023 ! galactolipid metabolic process GO:0019374 7 5 0,000 5,992E-03 0,05766792 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 5,992E-03 0,05742764 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 5,992E-03 0,05718935 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 5,992E-03 0,05695303 ! triglyceride catabolic process GO:0019433 6 5 0,000 5,992E-03 0,05671866 ! glial cell migration GO:0008347 10 5 0,000 5,992E-03 0,0564862 ! determination of adult lifespan GO:0008340 8 5 0,000 5,992E-03 0,05625565 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 5,992E-03 0,05602697 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 5,992E-03 0,05580014 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 5,992E-03 0,05557514 ! somatic stem cell maintenance GO:0035019 13 5 0,000 5,992E-03 0,05535194 ! cerebellar cortex formation GO:0021697 6 5 0,000 5,992E-03 0,05513053 ! neural plate development GO:0001840 6 5 0,000 5,992E-03 0,05491089 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 5,992E-03 0,05469299 ! regulation of sensory perception GO:0051931 6 5 0,000 5,992E-03 0,05447681 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 5,992E-03 0,05426234 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 5,992E-03 0,05404954 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 5,992E-03 0,05383841 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 5,992E-03 0,05362892 ! sensory cilium assembly GO:0035058 6 5 0,000 5,992E-03 0,05342106 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 5,992E-03 0,0532148 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 5,992E-03 0,05301013 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 5,992E-03 0,05280703 ! spindle assembly GO:0051225 5 5 0,000 5,992E-03 0,05260547 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 5,992E-03 0,05240545 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 5,992E-03 0,05220695 ! protein amino acid prenylation GO:0018346 9 5 0,000 5,992E-03 0,05200994 ! organ regeneration GO:0031100 7 5 0,000 5,992E-03 0,05181441 ! NAD biosynthetic process GO:0009435 7 5 0,000 5,992E-03 0,05162035 ! carnitine metabolic process GO:0009437 5 5 0,000 5,992E-03 0,05142774 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 5,992E-03 0,05123656 ! cellular anion homeostasis GO:0030002 6 5 0,000 5,992E-03 0,05104679 GO:0055081|anion homeostasis, ! regulation of translation GO:0006417 151 100 1,000 6,337E-03 0,05378685 ! tRNA transcription GO:0009304 11 6 0,000 7,187E-03 0,06077097 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 7,187E-03 0,06054837 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 7,187E-03 0,06032739 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 7,187E-03 0,06010802 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 7,187E-03 0,05989024 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 7,187E-03 0,05967402 ! regulation of helicase activity GO:0051095 11 6 0,000 7,187E-03 0,05945937 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 7,187E-03 0,05924625 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 7,187E-03 0,05903466 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 7,187E-03 0,05882457 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 7,187E-03 0,05861597 ! positive regulation of axon extension GO:0045773 8 6 0,000 7,187E-03 0,05840885 ! prostate gland development GO:0030850 9 6 0,000 7,187E-03 0,05820319 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 7,187E-03 0,05799896 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 7,187E-03 0,05779617 ! forebrain neuron differentiation GO:0021879 9 6 0,000 7,187E-03 0,05759479 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 7,187E-03 0,05739481 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 7,187E-03 0,05719621 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 7,187E-03 0,05699898 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 7,187E-03 0,05680311 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 7,187E-03 0,05660858 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 7,187E-03 0,05641537 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 7,187E-03 0,05622349 ! neuron adhesion GO:0007158 9 6 0,000 7,187E-03 0,0560329 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 7,187E-03 0,0558436 ! establishment of tissue polarity GO:0007164 7 6 0,000 7,187E-03 0,05565557 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 7,187E-03 0,05546881 ! signal peptide processing GO:0006465 8 6 0,000 7,187E-03 0,05528329 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 7,187E-03 0,05509902 ! mRNA stabilization GO:0048255 15 6 0,000 7,187E-03 0,05491596 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 7,187E-03 0,05473412 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 7,187E-03 0,05455348 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 7,187E-03 0,05437403 ! opsonization GO:0008228 8 6 0,000 7,187E-03 0,05419575 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 7,187E-03 0,05401864 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 7,187E-03 0,05384269 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 7,187E-03 0,05366787 ! protein amino acid dealkylation GO:0008214 11 6 0,000 7,187E-03 0,05349419 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 7,187E-03 0,05332163 ! photoreceptor cell development GO:0042461 10 6 0,000 7,187E-03 0,05315018 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 7,187E-03 0,05297982 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 7,187E-03 0,05281056 ! mechanosensory behavior GO:0007638 8 6 0,000 7,187E-03 0,05264237 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 7,187E-03 0,05247525 ! negative regulation of endocytosis GO:0045806 8 6 0,000 7,187E-03 0,05230919 ! response to interferon-gamma GO:0034341 12 6 0,000 7,187E-03 0,05214418 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 7,187E-03 0,0519802 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 7,187E-03 0,05181726 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 7,187E-03 0,05165533 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 7,187E-03 0,05149441 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 7,187E-03 0,05133449 ! cGMP-mediated signaling GO:0019934 10 6 0,000 7,187E-03 0,05117556 ! activation of MAPKKK activity GO:0000185 10 6 0,000 7,187E-03 0,05101761 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 7,187E-03 0,05086063 ! thymic T cell selection GO:0045061 12 6 0,000 7,187E-03 0,05070462 ! protein lipoylation GO:0009249 10 6 0,000 7,187E-03 0,05054956 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 7,187E-03 0,05039544 ! pigment granule organization GO:0048753 11 6 0,000 7,187E-03 0,05024226 ! drug transport GO:0015893 6 6 0,000 7,187E-03 0,05009001 ! cysteine metabolic process GO:0006534 7 6 0,000 7,187E-03 0,04993869 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 7,187E-03 0,04978827 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 7,187E-03 0,04963875 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 7,187E-03 0,04949013 ! histidine metabolic process GO:0006547 6 6 0,000 7,187E-03 0,0493424 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 7,187E-03 0,04919555 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 7,187E-03 0,04904957 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 7,187E-03 0,04890445 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 7,187E-03 0,04876019 ! adenohypophysis development GO:0021984 10 6 0,000 7,187E-03 0,04861678 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 7,187E-03 0,04847421 ! hyperosmotic response GO:0006972 8 6 0,000 7,187E-03 0,04833247 ! microtubule nucleation GO:0007020 10 6 0,000 7,187E-03 0,04819156 ! ER overload response GO:0006983 7 6 0,000 7,187E-03 0,04805147 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 7,187E-03 0,04791219 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 7,187E-03 0,04777371 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 7,187E-03 0,04763604 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 7,187E-03 0,04749915 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 7,187E-03 0,04736305 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 7,187E-03 0,04722773 ! response to dietary excess GO:0002021 7 6 0,000 7,187E-03 0,04709318 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 7,187E-03 0,04695939 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 7,187E-03 0,04682636 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 7,187E-03 0,04669408 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 7,187E-03 0,04656255 ! glycerol ether catabolic process GO:0044269 8 6 0,000 7,187E-03 0,04643176 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 7,187E-03 0,04630169 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 7,187E-03 0,04617236 ! neuron apoptosis GO:0051402 8 6 0,000 7,187E-03 0,04604375 ! organic alcohol transport GO:0015850 9 6 0,000 7,187E-03 0,04591585 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 7,187E-03 0,04578866 ! T cell mediated immunity GO:0002456 12 6 0,000 7,187E-03 0,04566217 ! male sex determination GO:0030238 9 6 0,000 7,187E-03 0,04553638 ! carnitine transport GO:0015879 8 6 0,000 7,187E-03 0,04541128 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 7,187E-03 0,04528686 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 7,187E-03 0,04516313 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 7,187E-03 0,04504007 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 7,187E-03 0,04491768 ! positive regulation of exocytosis GO:0045921 6 6 0,000 7,187E-03 0,04479595 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 7,187E-03 0,04467488 ! parturition GO:0007567 12 6 0,000 7,187E-03 0,04455446 ! negative regulation of translational initiation GO:0045947 7 6 0,000 7,187E-03 0,04443469 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 7,187E-03 0,04431556 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 7,187E-03 0,04419707 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 7,187E-03 0,04407921 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 7,187E-03 0,04396198 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 7,187E-03 0,04384537 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 7,187E-03 0,04372938 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 7,187E-03 0,043614 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 7,187E-03 0,04349922 ! macrophage differentiation GO:0030225 10 6 0,000 7,187E-03 0,04338505 ! astrocyte development GO:0014002 14 6 0,000 7,187E-03 0,04327148 ! hyaluronan metabolic process GO:0030212 6 6 0,000 7,187E-03 0,0431585 ! purine base biosynthetic process GO:0009113 14 6 0,000 7,187E-03 0,04304611 ! interaction with symbiont GO:0051702 8 6 0,000 7,187E-03 0,0429343 ! anterograde axon cargo transport GO:0008089 8 6 0,000 7,187E-03 0,04282307 ! skeletal muscle contraction GO:0003009 6 6 0,000 7,187E-03 0,04271242 ! eating behavior GO:0042755 6 6 0,000 7,187E-03 0,04260233 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 7,187E-03 0,04249281 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 7,187E-03 0,04238386 ! response to copper ion GO:0046688 9 6 0,000 7,187E-03 0,04227546 ! DNA topological change GO:0006265 8 6 0,000 7,187E-03 0,04216761 ! response to exogenous dsRNA GO:0043330 8 6 0,000 7,187E-03 0,04206032 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 7,187E-03 0,04195357 ! establishment of melanosome localization GO:0032401 9 6 0,000 7,187E-03 0,04184735 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 7,187E-03 0,04174168 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 7,187E-03 0,04163654 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 7,187E-03 0,04153192 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 7,187E-03 0,04142783 ! nucleoside catabolic process GO:0009164 6 6 0,000 7,187E-03 0,04132426 ! gas homeostasis GO:0033483 11 6 0,000 7,187E-03 0,04122121 ! hair follicle maturation GO:0048820 7 6 0,000 7,187E-03 0,04111867 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 7,187E-03 0,04101664 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 7,187E-03 0,04091511 ! Schwann cell development GO:0014044 14 6 0,000 7,187E-03 0,04081409 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 7,187E-03 0,04071356 ! dendrite morphogenesis GO:0048813 9 6 0,000 7,187E-03 0,04061353 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 7,187E-03 0,04051398 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 7,187E-03 0,04041493 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 7,187E-03 0,04031635 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 7,187E-03 0,04021826 ! histone ubiquitination GO:0016574 7 6 0,000 7,187E-03 0,04012064 ! regulation of meiosis GO:0040020 10 6 0,000 7,187E-03 0,0400235 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 7,187E-03 0,03992682 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 7,187E-03 0,03983061 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 7,187E-03 0,03973487 ! regulation of mast cell activation GO:0033003 6 6 0,000 7,187E-03 0,03963958 ! membrane to membrane docking GO:0022614 12 6 0,000 7,187E-03 0,03954475 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 7,187E-03 0,03945037 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 7,187E-03 0,03935644 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 7,187E-03 0,03926296 ! receptor internalization GO:0031623 9 6 0,000 7,187E-03 0,03916992 ! neutrophil homeostasis GO:0001780 6 6 0,000 7,187E-03 0,03907732 ! coenzyme A metabolic process GO:0015936 9 6 0,000 7,187E-03 0,03898515 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 7,187E-03 0,03889342 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 7,187E-03 0,03880212 ! protein deubiquitination GO:0016579 8 6 0,000 7,187E-03 0,03871125 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 7,187E-03 0,03862081 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 7,187E-03 0,03853078 ! peptidyl-histidine modification GO:0018202 9 6 0,000 7,187E-03 0,03844117 ! axonal fasciculation GO:0007413 9 6 0,000 7,187E-03 0,03835198 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 7,187E-03 0,03826321 ! thiamin metabolic process GO:0006772 6 6 0,000 7,187E-03 0,03817484 ! midbrain development GO:0030901 6 6 0,000 7,187E-03 0,03808688 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 7,187E-03 0,03799932 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 7,187E-03 0,03791217 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 7,187E-03 0,03782541 ! progesterone metabolic process GO:0042448 8 6 0,000 7,187E-03 0,03773905 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 7,187E-03 0,03765309 ! glycolipid catabolic process GO:0019377 13 6 0,000 7,187E-03 0,03756751 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 7,187E-03 0,03748232 ! positive regulation of glucose import GO:0046326 6 6 0,000 7,187E-03 0,03739752 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 7,187E-03 0,0373131 ! adult feeding behavior GO:0008343 6 6 0,000 7,187E-03 0,03722907 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 7,187E-03 0,0371454 ! blastocyst growth GO:0001832 15 6 0,000 7,187E-03 0,03706212 ! pigment granule transport GO:0051904 12 6 0,000 7,187E-03 0,03697921 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 7,187E-03 0,03689666 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 7,187E-03 0,03681449 ! catecholamine transport GO:0051937 7 6 0,000 7,187E-03 0,03673268 ! organ or tissue specific immune response GO:0002251 7 6 0,000 7,187E-03 0,03665123 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 7,187E-03 0,03657014 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 7,187E-03 0,03648941 ! negative regulation of B cell activation GO:0050869 9 6 0,000 7,187E-03 0,03640904 ! protein prenylation GO:0018342 10 6 0,000 7,187E-03 0,03632902 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 7,187E-03 0,03624935 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 7,187E-03 0,03617003 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 7,187E-03 0,03609106 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 7,187E-03 0,03601243 ! positive regulation of coagulation GO:0050820 11 6 0,000 7,187E-03 0,03593414 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 8,38E-03 0,04180831 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 8,38E-03 0,04171782 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 8,38E-03 0,04162772 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 8,38E-03 0,041538 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 8,38E-03 0,04144867 ! synaptonemal complex assembly GO:0007130 10 7 0,000 8,38E-03 0,04135973 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 8,38E-03 0,04127116 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 8,38E-03 0,04118298 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 8,38E-03 0,04109516 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 8,38E-03 0,04100773 ! reproductive behavior GO:0019098 12 7 0,000 8,38E-03 0,04092066 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 8,38E-03 0,04083397 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 8,38E-03 0,04074764 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 8,38E-03 0,04066167 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 8,38E-03 0,04057607 ! oligopeptide transport GO:0006857 11 7 0,000 8,38E-03 0,04049082 ! protein amino acid sulfation GO:0006477 9 7 0,000 8,38E-03 0,04040594 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 8,38E-03 0,04032141 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 8,38E-03 0,04023723 ! RNA methylation GO:0001510 11 7 0,000 8,38E-03 0,0401534 ! pericardium development GO:0060039 8 7 0,000 8,38E-03 0,04006992 ! macrophage chemotaxis GO:0048246 10 7 0,000 8,38E-03 0,03998679 ! fibril organization GO:0043206 13 7 0,000 8,38E-03 0,039904 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 8,38E-03 0,03982155 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 8,38E-03 0,03973945 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 8,38E-03 0,03965768 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 8,38E-03 0,03957625 ! lipoprotein transport GO:0042953 9 7 0,000 8,38E-03 0,03949515 ! cerebral cortex cell migration GO:0021795 11 7 0,000 8,38E-03 0,03941438 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 8,38E-03 0,03933394 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 8,38E-03 0,03925383 ! estrogen metabolic process GO:0008210 14 7 0,000 8,38E-03 0,03917405 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 8,38E-03 0,03909459 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 8,38E-03 0,03901545 ! chemosensory behavior GO:0007635 9 7 0,000 8,38E-03 0,03893663 ! microtubule bundle formation GO:0001578 8 7 0,000 8,38E-03 0,03885813 ! T-helper 1 type immune response GO:0042088 11 7 0,000 8,38E-03 0,03877994 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 8,38E-03 0,03870207 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 8,38E-03 0,03862451 ! leukocyte degranulation GO:0043299 10 7 0,000 8,38E-03 0,03854726 ! bile acid and bile salt transport GO:0015721 9 7 0,000 8,38E-03 0,03847032 ! reflex GO:0060004 12 7 0,000 8,38E-03 0,03839369 ! positive regulation of isotype switching GO:0045830 15 7 0,000 8,38E-03 0,03831736 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 8,38E-03 0,03824133 ! protein-cofactor linkage GO:0018065 13 7 0,000 8,38E-03 0,03816561 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 8,38E-03 0,03809018 ! glycerolipid catabolic process GO:0046503 9 7 0,000 8,38E-03 0,03801505 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 8,38E-03 0,03794022 ! spinal cord patterning GO:0021511 7 7 0,000 8,38E-03 0,03786568 ! hemoglobin metabolic process GO:0020027 10 7 0,000 8,38E-03 0,03779144 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 8,38E-03 0,03771748 ! adrenal gland development GO:0030325 17 7 0,000 8,38E-03 0,03764381 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 8,38E-03 0,03757043 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 8,38E-03 0,03749734 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 8,38E-03 0,03742453 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 8,38E-03 0,037352 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 8,38E-03 0,03727975 ! endosome organization GO:0007032 10 7 0,000 8,38E-03 0,03720778 ! thyroid hormone generation GO:0006590 11 7 0,000 8,38E-03 0,03713609 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 8,38E-03 0,03706468 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 8,38E-03 0,03699354 ! regulation of pigmentation during development GO:0048070 15 7 0,000 8,38E-03 0,03692267 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 8,38E-03 0,03685207 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 8,38E-03 0,03678174 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 8,38E-03 0,03671168 ! galactose metabolic process GO:0006012 10 7 0,000 8,38E-03 0,03664189 ! vesicle fusion GO:0006906 15 7 0,000 8,38E-03 0,03657236 ! intracellular pH reduction GO:0051452 10 7 0,000 8,38E-03 0,03650309 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 8,38E-03 0,03643409 ! organ growth GO:0035265 11 7 0,000 8,38E-03 0,03636534 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 8,38E-03 0,03629686 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 8,38E-03 0,03622863 ! Rac protein signal transduction GO:0016601 7 7 0,000 8,38E-03 0,03616066 ! retinol metabolic process GO:0042572 9 7 0,000 8,38E-03 0,03609294 ! behavioral fear response GO:0001662 13 7 0,000 8,38E-03 0,03602548 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 8,38E-03 0,03595827 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 8,38E-03 0,03589131 ! rRNA modification GO:0000154 12 7 0,000 8,38E-03 0,0358246 ! protein heterooligomerization GO:0051291 10 7 0,000 8,38E-03 0,03575813 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 8,38E-03 0,03569191 ! response to UV-B GO:0010224 11 7 0,000 8,38E-03 0,03562594 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 8,38E-03 0,03556021 ! protein retention in ER lumen GO:0006621 12 7 0,000 8,38E-03 0,03549472 ! intermediate filament organization GO:0045109 11 7 0,000 8,38E-03 0,03542947 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 8,38E-03 0,03536446 ! cardiac muscle cell development GO:0055013 9 7 0,000 8,38E-03 0,03529969 ! fibrinolysis GO:0042730 9 7 0,000 8,38E-03 0,03523516 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 8,38E-03 0,03517086 ! regulation of circadian rhythm GO:0042752 11 7 0,000 8,38E-03 0,0351068 ! B cell lineage commitment GO:0002326 17 7 0,000 8,38E-03 0,03504297 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 8,38E-03 0,03497937 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 8,38E-03 0,034916 ! response to tropane GO:0014073 13 7 0,000 8,38E-03 0,03485286 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 8,38E-03 0,03478995 ! melanosome localization GO:0032400 10 7 0,000 8,38E-03 0,03472727 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 8,38E-03 0,03466481 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 8,38E-03 0,03460257 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 8,38E-03 0,03454056 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 8,38E-03 0,03447877 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 8,38E-03 0,0344172 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 8,38E-03 0,03435585 ! mast cell activation GO:0045576 9 7 0,000 8,38E-03 0,03429472 ! multicellular organismal aging GO:0010259 11 7 0,000 8,38E-03 0,03423381 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 8,38E-03 0,03417311 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 8,38E-03 0,03411262 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 8,38E-03 0,03405235 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 8,38E-03 0,0339923 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 8,38E-03 0,03393245 ! establishment of nucleus localization GO:0040023 13 7 0,000 8,38E-03 0,03387282 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 8,38E-03 0,03381339 ! T cell lineage commitment GO:0002360 12 7 0,000 8,38E-03 0,03375417 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 8,38E-03 0,03369516 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 8,38E-03 0,03363636 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 8,38E-03 0,03357776 ! regulation of lipid transport GO:0032368 13 7 0,000 8,38E-03 0,03351936 ! response to tumor cell GO:0002347 12 7 0,000 8,38E-03 0,03346117 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 8,38E-03 0,03340318 ! neuroblast proliferation GO:0007405 13 7 0,000 8,38E-03 0,03334538 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 8,38E-03 0,03328779 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 8,38E-03 0,0332304 ! peptidyl-threonine modification GO:0018210 18 7 0,000 8,38E-03 0,03317321 ! diuresis GO:0030146 12 7 0,000 8,38E-03 0,03311621 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 8,38E-03 0,0330594 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 8,38E-03 0,0330028 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 8,38E-03 0,03294638 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 8,38E-03 0,03289016 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 8,38E-03 0,03283413 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 8,38E-03 0,03277829 ! melanin biosynthetic process GO:0042438 8 7 0,000 8,38E-03 0,03272264 ! regulation of synaptogenesis GO:0051963 10 7 0,000 8,38E-03 0,03266717 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 8,38E-03 0,0326119 ! dopamine biosynthetic process GO:0042416 15 7 0,000 8,38E-03 0,03255681 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 8,38E-03 0,03250191 ! lymph node development GO:0048535 9 7 0,000 8,38E-03 0,03244719 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 8,38E-03 0,03239266 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 8,38E-03 0,03233831 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 8,38E-03 0,03228414 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 8,38E-03 0,03223015 ! endosome to lysosome transport GO:0008333 10 7 0,000 8,38E-03 0,03217635 ! ATP catabolic process GO:0006200 10 7 0,000 8,38E-03 0,03212272 ! establishment of pigment granule localization GO:0051905 13 7 0,000 8,38E-03 0,03206927 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 8,38E-03 0,032016 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 8,38E-03 0,03196291 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 8,38E-03 0,03190999 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 8,38E-03 0,03185724 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 8,38E-03 0,03180467 ! muscle adaptation GO:0043500 12 7 0,000 8,38E-03 0,03175228 ! amino sugar catabolic process GO:0046348 9 7 0,000 8,38E-03 0,03170005 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 8,38E-03 0,031648 ! retina homeostasis GO:0001895 9 7 0,000 8,38E-03 0,03159612 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 8,38E-03 0,03154441 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 8,38E-03 0,03149286 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 8,38E-03 0,03144149 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 8,38E-03 0,03139028 ! behavioral response to nicotine GO:0035095 11 7 0,000 8,38E-03 0,03133924 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 8,38E-03 0,03128836 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 8,38E-03 0,03123765 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 9,571E-03 0,03562204 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 9,571E-03 0,03556449 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 9,571E-03 0,03550713 ! axon extension GO:0048675 11 8 0,000 9,571E-03 0,03544995 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 9,571E-03 0,03539296 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 9,571E-03 0,03533615 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 9,571E-03 0,03527952 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 9,571E-03 0,03522307 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 9,571E-03 0,0351668 ! cell proliferation in forebrain GO:0021846 10 8 0,000 9,571E-03 0,03511072 ! positive regulation of B cell proliferation GO:0030890 11 8 0,000 9,571E-03 0,03505481 ! phosphate transport GO:0006817 10 8 0,000 9,571E-03 0,03499908 ! N-glycan processing GO:0006491 12 8 0,000 9,571E-03 0,03494352 ! Golgi to endosome transport GO:0006895 16 8 0,000 9,571E-03 0,03488814 ! UTP metabolic process GO:0046051 8 8 0,000 9,571E-03 0,03483294 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 9,571E-03 0,03477791 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 9,571E-03 0,03472306 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 9,571E-03 0,03466838 ! neurotransmitter uptake GO:0001504 10 8 0,000 9,571E-03 0,03461387 ! succinate metabolic process GO:0006105 14 8 0,000 9,571E-03 0,03455953 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 9,571E-03 0,03450536 ! smoothened signaling pathway GO:0007224 8 8 0,000 9,571E-03 0,03445136 ! membrane hyperpolarization GO:0060081 10 8 0,000 9,571E-03 0,03439753 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 9,571E-03 0,03434387 ! keratinocyte proliferation GO:0043616 12 8 0,000 9,571E-03 0,03429037 ! middle ear morphogenesis GO:0042474 9 8 0,000 9,571E-03 0,03423704 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 9,571E-03 0,03418388 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 9,571E-03 0,03413088 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 9,571E-03 0,03407805 ! ganglioside metabolic process GO:0001573 15 8 0,000 9,571E-03 0,03402538 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 9,571E-03 0,03397287 ! pseudouridine synthesis GO:0001522 9 8 0,000 9,571E-03 0,03392052 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 9,571E-03 0,03386834 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 9,571E-03 0,03381631 ! endothelial cell differentiation GO:0045446 14 8 0,000 9,571E-03 0,03376445 ! ceramide biosynthetic process GO:0046513 9 8 0,000 9,571E-03 0,03371274 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 9,571E-03 0,03366119 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 0,000 9,571E-03 0,0336098 ! astrocyte differentiation GO:0048708 16 8 0,000 9,571E-03 0,03355857 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 9,571E-03 0,03350749 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 9,571E-03 0,03345656 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 9,571E-03 0,0334058 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 9,571E-03 0,03335518 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 9,571E-03 0,03330472 ! melanin metabolic process GO:0006582 12 8 0,000 9,571E-03 0,03325441 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 9,571E-03 0,03320425 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 9,571E-03 0,03315425 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 9,571E-03 0,03310439 ! macrophage activation GO:0042116 12 8 0,000 9,571E-03 0,03305468 ! regulation of type I interferon production GO:0032479 8 8 0,000 9,571E-03 0,03300513 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 9,571E-03 0,03295572 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 9,571E-03 0,03290646 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 9,571E-03 0,03285734 ! regulation of vascular permeability GO:0043114 12 8 0,000 9,571E-03 0,03280837 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 9,571E-03 0,03275955 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 9,571E-03 0,03271088 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 9,571E-03 0,03266234 ! ruffle organization GO:0031529 11 8 0,000 9,571E-03 0,03261395 ! osteoblast development GO:0002076 13 8 0,000 9,571E-03 0,03256571 ! lens development in camera-type eye GO:0002088 10 8 0,000 9,571E-03 0,03251761 ! positive regulation of vasodilation GO:0045909 12 8 0,000 9,571E-03 0,03246965 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 9,571E-03 0,03242183 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 9,571E-03 0,03237415 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 9,571E-03 0,03232661 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 9,571E-03 0,03227921 ! Schwann cell differentiation GO:0014037 17 8 0,000 9,571E-03 0,03223195 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 9,571E-03 0,03218482 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 9,571E-03 0,03213784 ! regulation of gliogenesis GO:0014013 20 8 0,000 9,571E-03 0,03209099 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 9,571E-03 0,03204428 ! oligodendrocyte development GO:0014003 8 8 0,000 9,571E-03 0,0319977 ! segment specification GO:0007379 10 8 0,000 9,571E-03 0,03195126 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 9,571E-03 0,03190496 ! cellular extravasation GO:0045123 11 8 0,000 9,571E-03 0,03185878 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 9,571E-03 0,03181274 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 9,571E-03 0,03176684 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 9,571E-03 0,03172107 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 9,571E-03 0,03167542 ! snRNA metabolic process GO:0016073 10 8 0,000 9,571E-03 0,03162991 GO:0016180|snRNA processing, ! phosphoinositide 3-kinase cascade GO:0014065 23 8 0,000 9,571E-03 0,03158453 ! regulation of interleukin-4 production GO:0032673 16 8 0,000 9,571E-03 0,03153928 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 9,571E-03 0,03149416 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 9,571E-03 0,03144917 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 9,571E-03 0,03140431 ! nucleosome disassembly GO:0006337 12 8 0,000 9,571E-03 0,03135957 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 9,571E-03 0,03131496 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 9,571E-03 0,03127048 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 9,571E-03 0,03122613 ! icosanoid secretion GO:0032309 12 8 0,000 9,571E-03 0,0311819 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 9,571E-03 0,03113779 ! leukocyte activation during immune response GO:0002366 13 8 0,000 9,571E-03 0,03109381 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 9,571E-03 0,03104996 ! cerebellum morphogenesis GO:0021587 9 8 0,000 9,571E-03 0,03100622 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 9,571E-03 0,03096262 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 9,571E-03 0,03091913 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 9,571E-03 0,03087576 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 9,571E-03 0,03083252 ! sterol catabolic process GO:0016127 9 8 0,000 9,571E-03 0,0307894 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 9,571E-03 0,0307464 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 9,571E-03 0,03070351 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 9,571E-03 0,03066075 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 9,571E-03 0,03061811 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 9,571E-03 0,03057558 ! prophase GO:0051324 11 8 0,000 9,571E-03 0,03053318 ! S phase GO:0051320 8 8 0,000 9,571E-03 0,03049089 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 9,571E-03 0,03044871 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 9,571E-03 0,03040666 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 9,571E-03 0,03036472 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 9,571E-03 0,03032289 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 9,571E-03 0,03028118 ! hormone catabolic process GO:0042447 13 8 0,000 9,571E-03 0,03023959 ! quaternary ammonium group transport GO:0015697 10 8 0,000 9,571E-03 0,03019811 ! myeloid cell homeostasis GO:0002262 8 8 0,000 9,571E-03 0,03015674 ! regulation of fibrinolysis GO:0051917 13 8 0,000 9,571E-03 0,03011548 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 9,571E-03 0,03007434 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 9,571E-03 0,03003331 ! regulation of telomere maintenance GO:0032204 10 8 0,000 9,571E-03 0,0299924 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 9,571E-03 0,02995159 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 9,571E-03 0,0299109 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 9,571E-03 0,02987031 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 9,571E-03 0,02982984 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 9,571E-03 0,02978947 ! lamellipodium assembly GO:0030032 9 8 0,000 9,571E-03 0,02974922 ! regulation of embryonic development GO:0045995 16 8 0,000 9,571E-03 0,02970907 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 9,571E-03 0,02966903 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 9,571E-03 0,0296291 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 9,571E-03 0,02958927 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,01076177 0,03322425 ! regulation of developmental growth GO:0048638 13 9 0,000 0,01076177 0,03317972 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,01076177 0,0331353 ! telencephalon cell migration GO:0022029 16 9 0,000 0,01076177 0,033091 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,01076177 0,03304682 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,01076177 0,03300276 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,01076177 0,03295881 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,01076177 0,03291499 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,01076177 0,03287127 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,01076177 0,03282768 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,01076177 0,0327842 ! GTP metabolic process GO:0046039 9 9 0,000 0,01076177 0,03274083 ! elastic fiber assembly GO:0048251 13 9 0,000 0,01076177 0,03269758 ! social behavior GO:0035176 14 9 0,000 0,01076177 0,03265445 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,01076177 0,03261142 ! artery development GO:0060840 19 9 0,000 0,01076177 0,03256851 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,01076177 0,03252572 ! regulation of glycolysis GO:0006110 15 9 0,000 0,01076177 0,03248303 ! response to pain GO:0048265 16 9 0,000 0,01076177 0,03244046 ! protein complex disassembly GO:0043241 17 9 0,000 0,01076177 0,032398 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,01076177 0,03235565 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,01076177 0,03231341 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,01076177 0,03227128 ! lung alveolus development GO:0048286 17 9 0,000 0,01076177 0,03222926 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,01076177 0,03218735 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,01076177 0,03214554 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,01076177 0,03210385 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,01076177 0,03206227 ! ventral spinal cord development GO:0021517 11 9 0,000 0,01076177 0,03202079 ! protein targeting to ER GO:0045047 19 9 0,000 0,01076177 0,03197942 ! T cell selection GO:0045058 18 9 0,000 0,01076177 0,03193815 ! endoderm development GO:0007492 12 9 0,000 0,01076177 0,031897 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,01076177 0,03185595 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,01076177 0,031815 ! arginine catabolic process GO:0006527 10 9 0,000 0,01076177 0,03177416 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,01076177 0,03173342 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,01076177 0,03169279 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,01076177 0,03165226 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01076177 0,03161184 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,01076177 0,03157152 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,01076177 0,0315313 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,01076177 0,03149118 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,01076177 0,03145117 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01076177 0,03141126 ! mannose metabolic process GO:0006013 9 9 0,000 0,01076177 0,03137144 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,01076177 0,03133173 ! receptor clustering GO:0043113 15 9 0,000 0,01076177 0,03129212 ! epithelial cell development GO:0002064 10 9 0,000 0,01076177 0,03125261 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,01076177 0,0312132 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,01076177 0,03117389 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,01076177 0,03113468 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,01076177 0,03109556 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,01076177 0,03105655 ! motor axon guidance GO:0008045 14 9 0,000 0,01076177 0,03101763 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,01076177 0,03097881 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,01076177 0,03094009 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,01076177 0,03090146 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,01076177 0,03086293 ! blastoderm segmentation GO:0007350 11 9 0,000 0,01076177 0,03082449 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,01076177 0,03078616 ! DNA ligation GO:0006266 14 9 0,000 0,01076177 0,03074791 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,01076177 0,03070976 ! response to amine stimulus GO:0014075 13 9 0,000 0,01076177 0,03067171 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,01076177 0,03063375 ! erythrocyte development GO:0048821 11 9 0,000 0,01076177 0,03059588 ! renal water homeostasis GO:0003091 14 9 0,000 0,01076177 0,03055811 ! postreplication repair GO:0006301 11 9 0,000 0,01076177 0,03052043 ! mRNA cleavage GO:0006379 13 9 0,000 0,01076177 0,03048284 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,01076177 0,03044535 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,01076177 0,03040795 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,01076177 0,03037064 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,01076177 0,03033342 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,01076177 0,03029629 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,01076177 0,03025925 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,01076177 0,03022231 ! acid secretion GO:0046717 14 9 0,000 0,01076177 0,03018545 ! musculoskeletal movement GO:0050881 11 9 0,000 0,01076177 0,03014868 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,01076177 0,03011201 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,01076177 0,03007542 ! purine base metabolic process GO:0006144 18 9 0,000 0,01076177 0,03003892 ! oocyte differentiation GO:0009994 12 9 0,000 0,01076177 0,03000251 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,01076177 0,02996619 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,01076177 0,02992995 ! spleen development GO:0048536 15 9 0,000 0,01076177 0,0298938 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,01076177 0,02985774 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,01076177 0,02982177 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,01076177 0,02978588 ! detection of calcium ion GO:0005513 13 9 0,000 0,01076177 0,02975008 ! blastocyst formation GO:0001825 12 9 0,000 0,01076177 0,02971437 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,01076177 0,02967874 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,01076177 0,0296432 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,01076177 0,02960774 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,01076177 0,02957236 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01076177 0,02953708 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,01076177 0,02950187 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,01076177 0,02946675 ! prepulse inhibition GO:0060134 14 9 0,000 0,01076177 0,02943171 ! embryonic placenta development GO:0001892 12 9 0,000 0,01076177 0,02939676 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,01076177 0,02936189 ! insulin secretion GO:0030073 17 9 0,000 0,01076177 0,0293271 ! sequestering of metal ion GO:0051238 11 9 0,000 0,01076177 0,02929239 ! response to nicotine GO:0035094 16 9 0,000 0,01076177 0,02925777 ! establishment of cell polarity GO:0030010 12 9 0,000 0,01076177 0,02922322 ! nucleus localization GO:0051647 15 9 0,000 0,01076177 0,02918876 ! regulation of synapse organization GO:0050807 12 9 0,000 0,01076177 0,02915438 ! localization within membrane GO:0051668 15 9 0,000 0,01076177 0,02912008 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,01195069 0,03229916 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,01195069 0,03226125 ! neuron fate specification GO:0048665 11 10 0,000 0,01195069 0,03222343 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,01195069 0,0321857 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,01195069 0,03214805 ! thyroid gland development GO:0030878 19 10 0,000 0,01195069 0,0321105 ! regulation of B cell proliferation GO:0030888 15 10 0,000 0,01195069 0,03207303 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,01195069 0,03203565 ! synapsis GO:0007129 13 10 0,000 0,01195069 0,03199835 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,01195069 0,03196115 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,01195069 0,03192403 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,01195069 0,03188699 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,01195069 0,03185004 ! sulfate transport GO:0008272 12 10 0,000 0,01195069 0,03181318 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,01195069 0,0317764 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,01195069 0,03173971 ! androgen metabolic process GO:0008209 13 10 0,000 0,01195069 0,0317031 ! phospholipid efflux GO:0033700 16 10 0,000 0,01195069 0,03166657 ! hippocampus development GO:0021766 19 10 0,000 0,01195069 0,03163013 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,01195069 0,03159378 ! blood vessel remodeling GO:0001974 21 10 0,000 0,01195069 0,0315575 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,01195069 0,03152131 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,01195069 0,03148521 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,01195069 0,03144918 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,01195069 0,03141324 ! pathogenesis GO:0009405 13 10 0,000 0,01195069 0,03137738 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,01195069 0,0313416 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01195069 0,03130591 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,01195069 0,03127029 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 0,01195069 0,03123476 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,01195069 0,0311993 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,01195069 0,03116393 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,01195069 0,03112864 ! melanocyte differentiation GO:0030318 15 10 0,000 0,01195069 0,03109342 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,01195069 0,03105829 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,01195069 0,03102323 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,01195069 0,03098826 ! response to X-ray GO:0010165 16 10 0,000 0,01195069 0,03095336 ! B cell proliferation GO:0042100 14 10 0,000 0,01195069 0,03091854 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,01195069 0,0308838 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,01195069 0,03084914 ! forebrain cell migration GO:0021885 17 10 0,000 0,01195069 0,03081456 ! lipid digestion GO:0044241 15 10 0,000 0,01195069 0,03078005 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,01195069 0,03074562 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,01195069 0,03071127 ! UV protection GO:0009650 14 10 0,000 0,01195069 0,03067699 ! entry into host cell GO:0030260 20 10 0,000 0,01195069 0,03064279 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,01195069 0,03060867 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,01195069 0,03057462 ! negative regulation of ossification GO:0030279 19 10 0,000 0,01195069 0,03054065 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,01195069 0,03050675 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,01195069 0,03047293 ! regulation of bone resorption GO:0045124 24 10 0,000 0,01195069 0,03043919 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,01195069 0,03040552 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,01195069 0,03037192 ! regulation of organ growth GO:0046620 11 10 0,000 0,01195069 0,0303384 ! response to dsRNA GO:0043331 18 10 0,000 0,01195069 0,03030495 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,01195069 0,03027157 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,01195069 0,03023827 ! embryonic axis specification GO:0000578 12 10 0,000 0,01195069 0,03020504 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,01195069 0,03017188 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,01195069 0,0301388 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,01195069 0,03010579 ! cranial nerve development GO:0021545 12 10 0,000 0,01195069 0,03007285 ! fucose catabolic process GO:0019317 16 10 0,000 0,01195069 0,03003998 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,01195069 0,03000719 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,01195069 0,02997447 ! protein sumoylation GO:0016925 12 10 0,000 0,01195069 0,02994181 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,01195069 0,02990923 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01195069 0,02987672 ! zymogen activation GO:0031638 14 10 0,000 0,01195069 0,02984428 ! salivary gland development GO:0007431 22 10 0,000 0,01195069 0,02981192 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,01195069 0,02977962 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,01195069 0,02974739 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,01195069 0,02971523 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,01195069 0,02968314 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,01195069 0,02965112 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,01195069 0,02961917 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,01195069 0,02958728 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,01195069 0,02955547 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,01195069 0,02952372 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,01195069 0,02949204 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,01195069 0,02946044 ! detection of bacterium GO:0016045 10 10 0,000 0,01195069 0,02942889 ! embryonic gut development GO:0048566 11 10 0,000 0,01195069 0,02939742 ! activation of innate immune response GO:0002218 10 10 0,000 0,01195069 0,02936601 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,01195069 0,02933467 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,01195069 0,0293034 ! developmental induction GO:0031128 13 10 0,000 0,01195069 0,02927219 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,01195069 0,02924105 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,01195069 0,02920997 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,01195069 0,02917897 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,01195069 0,02914802 ! rRNA transcription GO:0009303 17 11 0,000 0,01313825 0,03201056 ! respiratory burst GO:0045730 14 11 0,000 0,01313825 0,03197669 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,01313825 0,03194289 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,01313825 0,03190916 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,01313825 0,0318755 ! virus-host interaction GO:0019048 17 11 0,000 0,01313825 0,03184191 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 0,01313825 0,03180839 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,01313825 0,03177494 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,01313825 0,03174157 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,01313825 0,03170826 ! RNA polyadenylation GO:0043631 19 11 0,000 0,01313825 0,03167502 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,01313825 0,03164186 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,01313825 0,03160876 ! mating GO:0007618 14 11 0,000 0,01313825 0,03157573 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,01313825 0,03154277 ! T cell proliferation GO:0042098 20 11 0,000 0,01313825 0,03150988 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,01313825 0,03147705 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,01313825 0,0314443 ! bone resorption GO:0045453 16 11 0,000 0,01313825 0,03141161 ! regulated secretory pathway GO:0045055 14 11 0,000 0,01313825 0,031379 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,01313825 0,03134644 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,01313825 0,03131396 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,01313825 0,03128154 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,01313825 0,0312492 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,01313825 0,03121691 ! syncytium formation GO:0006949 15 11 0,000 0,01313825 0,0311847 ! plasma membrane organization GO:0007009 18 11 0,000 0,01313825 0,03115255 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,01313825 0,03112047 ! focal adhesion formation GO:0048041 24 11 0,000 0,01313825 0,03108845 ! mitotic spindle organization GO:0007052 15 11 0,000 0,01313825 0,0310565 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,01313825 0,03102461 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,01313825 0,03099279 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,01313825 0,03096104 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,01313825 0,03092935 ! adult heart development GO:0007512 11 11 0,000 0,01313825 0,03089772 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,01313825 0,03086616 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,01313825 0,03083467 ! temperature homeostasis GO:0001659 16 11 0,000 0,01313825 0,03080323 ! L-glutamate transport GO:0015813 16 11 0,000 0,01313825 0,03077187 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,01313825 0,03074056 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,01313825 0,03070932 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,01313825 0,03067814 ! stem cell development GO:0048864 29 11 0,000 0,01313825 0,03064703 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,01313825 0,03061598 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,01313825 0,03058499 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,01313825 0,03055407 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,01313825 0,0305232 ! vasoconstriction GO:0042310 15 11 0,000 0,01313825 0,0304924 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,01313825 0,03046167 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,01313825 0,03043099 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,01313825 0,03040037 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,01313825 0,03036982 ! ribosome assembly GO:0042255 13 11 0,000 0,01313825 0,03033933 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,01313825 0,0303089 GO:0006809|nitric oxide biosynthetic process, ! chromatin silencing GO:0006342 19 11 0,000 0,01313825 0,03027853 ! nucleosome positioning GO:0016584 13 11 0,000 0,01313825 0,03024822 ! T cell homeostasis GO:0043029 20 11 0,000 0,01313825 0,03021797 ! regulation of isotype switching GO:0045191 19 11 0,000 0,01313825 0,03018778 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,01313825 0,03015766 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,01313825 0,03012759 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,01313825 0,03009758 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,01313825 0,03006763 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,01313825 0,03003775 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,01313825 0,03000792 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,01313825 0,02997815 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,01313825 0,02994844 ! male genitalia development GO:0030539 13 11 0,000 0,01313825 0,02991878 ! cholesterol efflux GO:0033344 19 11 0,000 0,01313825 0,02988919 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,01313825 0,02985966 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,01313825 0,02983018 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,01313825 0,02980076 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,01313825 0,0297714 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,01313825 0,0297421 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,01313825 0,02971285 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,01313825 0,02968367 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,01313825 0,02965454 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,01313825 0,02962546 ! lysogeny GO:0030069 18 11 0,000 0,01313825 0,02959645 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,01313825 0,02956749 ! acrosome reaction GO:0007340 13 11 0,000 0,01313825 0,02953858 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,01313825 0,02950974 ! lactation GO:0007595 20 12 0,000 0,01432445 0,03214267 ! reproductive cellular process GO:0048610 14 12 0,000 0,01432445 0,03211134 ! tRNA modification GO:0006400 14 12 0,000 0,01432445 0,03208007 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,01432445 0,03204886 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,01432445 0,03201772 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,01432445 0,03198663 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,01432445 0,03195561 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,01432445 0,03192464 ! non-recombinational repair GO:0000726 19 12 0,000 0,01432445 0,03189374 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,01432445 0,03186289 ! peroxisomal transport GO:0043574 21 12 0,000 0,01432445 0,03183211 ! cartilage condensation GO:0001502 18 12 0,000 0,01432445 0,03180138 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,01432445 0,03177072 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,01432445 0,03174011 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,01432445 0,03170956 ! heart looping GO:0001947 15 12 0,000 0,01432445 0,03167907 ! palate development GO:0060021 15 12 0,000 0,01432445 0,03164864 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,01432445 0,03161826 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,01432445 0,03158795 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,01432445 0,03155769 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,01432445 0,03152749 ! arginine metabolic process GO:0006525 13 12 0,000 0,01432445 0,03149735 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,01432445 0,03146727 ! methionine metabolic process GO:0006555 13 12 0,000 0,01432445 0,03143724 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,01432445 0,03140728 ! Golgi organization GO:0007030 18 12 0,000 0,01432445 0,03137736 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,01432445 0,03134751 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,01432445 0,03131771 ! monoamine transport GO:0015844 13 12 0,000 0,01432445 0,03128797 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01432445 0,03125828 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,01432445 0,03122866 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,01432445 0,03119908 ! L-amino acid transport GO:0015807 20 12 0,000 0,01432445 0,03116957 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,01432445 0,03114011 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,01432445 0,0311107 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,01432445 0,03108135 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,01432445 0,03105206 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,01432445 0,03102282 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,01432445 0,03099363 ! cerebellum development GO:0021549 13 12 0,000 0,01432445 0,0309645 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,01432445 0,03093543 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,01432445 0,03090641 ! histone acetylation GO:0016573 23 12 0,000 0,01432445 0,03087744 ! histone methylation GO:0016571 15 12 0,000 0,01432445 0,03084853 ! autonomic nervous system development GO:0048483 23 12 0,000 0,01432445 0,03081967 ! gland morphogenesis GO:0022612 23 12 0,000 0,01432445 0,03079087 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,01432445 0,03076212 ! peptidyl-lysine modification GO:0018205 18 12 0,000 0,01432445 0,03073343 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,01432445 0,03070478 ! response to gamma radiation GO:0010332 20 12 0,000 0,01432445 0,03067619 ! regulation of epidermis development GO:0045682 17 12 0,000 0,01432445 0,03064766 ! intestinal absorption GO:0050892 19 12 0,000 0,01432445 0,03061917 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,01432445 0,03059074 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,01432445 0,03056237 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,01432445 0,03053404 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,01432445 0,03050577 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,01432445 0,03047755 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,01432445 0,03044938 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,01432445 0,03042127 ! microspike assembly GO:0030035 23 12 0,000 0,01432445 0,0303932 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,01432445 0,03036519 ! response to cold GO:0009409 14 12 0,000 0,01432445 0,03033723 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 0,01550929 0,03281635 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,01550929 0,03278618 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,01550929 0,03275608 ! cGMP metabolic process GO:0046068 16 13 0,000 0,01550929 0,03272603 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,01550929 0,03269603 ! water transport GO:0006833 17 13 0,000 0,01550929 0,03266609 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,01550929 0,0326362 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,01550929 0,03260637 ! lipid localization GO:0010876 24 13 0,000 0,01550929 0,03257659 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,01550929 0,03254687 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,01550929 0,0325172 ! organelle fusion GO:0048284 28 13 0,000 0,01550929 0,03248758 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,01550929 0,03245802 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,01550929 0,03242852 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,01550929 0,03239906 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,01550929 0,03236966 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,01550929 0,03234032 ! response to hexose stimulus GO:0009746 19 13 0,000 0,01550929 0,03231102 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,01550929 0,03228178 ! glutamate metabolic process GO:0006536 18 13 0,000 0,01550929 0,03225259 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,01550929 0,03222346 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,01550929 0,03219438 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,01550929 0,03216535 ! NAD metabolic process GO:0019674 21 13 0,000 0,01550929 0,03213637 ! exocrine system development GO:0035272 27 13 0,000 0,01550929 0,03210744 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,01550929 0,03207857 ! bone mineralization GO:0030282 15 13 0,000 0,01550929 0,03204975 ! regulation of exocytosis GO:0017157 17 13 0,000 0,01550929 0,03202098 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,01550929 0,03199226 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,01550929 0,03196359 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,01550929 0,03193498 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,01550929 0,03190641 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,01550929 0,0318779 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,01550929 0,03184944 ! genitalia development GO:0048806 15 13 0,000 0,01550929 0,03182102 ! regulation of cellular pH GO:0030641 20 13 0,000 0,01550929 0,03179266 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 0,01550929 0,03176435 ! cellular pigmentation GO:0033059 24 13 0,000 0,01550929 0,03173609 ! tissue regeneration GO:0042246 21 13 0,000 0,01550929 0,03170788 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,01550929 0,03167972 ! cofactor transport GO:0051181 19 13 0,000 0,01550929 0,03165161 ! NADP metabolic process GO:0006739 18 13 0,000 0,01550929 0,03162355 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,01550929 0,03159554 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,01550929 0,03156758 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,01550929 0,03153967 ! gas transport GO:0015669 18 13 0,000 0,01550929 0,03151181 ! regulation of RNA stability GO:0043487 28 13 0,000 0,01550929 0,031484 ! heme biosynthetic process GO:0006783 20 13 0,000 0,01550929 0,03145623 ! regulation of axon extension GO:0030516 23 13 0,000 0,01550929 0,03142852 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,01550929 0,03140085 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,01550929 0,03137323 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,01550929 0,03134567 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,01550929 0,03131815 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,01550929 0,03129067 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,01550929 0,03126325 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,01669278 0,03361943 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,01669278 0,03359001 ! superoxide anion generation GO:0042554 18 14 0,000 0,01669278 0,03356065 ! neuron maturation GO:0042551 21 14 0,000 0,01669278 0,03353134 ! regulation of S phase GO:0033261 18 14 0,000 0,01669278 0,03350208 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,01669278 0,03347287 ! myotube differentiation GO:0014902 21 14 0,000 0,01669278 0,03344371 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 0,01669278 0,03341461 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,01669278 0,03338555 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,01669278 0,03335655 ! inositol metabolic process GO:0006020 20 14 0,000 0,01669278 0,03332759 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,01669278 0,03329869 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,01669278 0,03326983 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,01669278 0,03324103 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,01669278 0,03321227 ! gene silencing by RNA GO:0031047 20 14 0,000 0,01669278 0,03318356 ! response to cAMP GO:0051591 19 14 0,000 0,01669278 0,03315491 ! limbic system development GO:0021761 25 14 0,000 0,01669278 0,0331263 ! startle response GO:0001964 21 14 0,000 0,01669278 0,03309774 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,01669278 0,03306924 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,01669278 0,03304078 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,01669278 0,03301237 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,01669278 0,03298401 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,01669278 0,03295569 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,01669278 0,03292743 ! glycine metabolic process GO:0006544 22 14 0,000 0,01669278 0,03289922 ! pituitary gland development GO:0021983 23 14 0,000 0,01669278 0,03287105 ! cellular response to starvation GO:0009267 21 14 0,000 0,01669278 0,03284293 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,01669278 0,03281486 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,01669278 0,03278684 ! regulation of heart rate GO:0002027 23 14 0,000 0,01669278 0,03275886 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,01669278 0,03273093 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,01669278 0,03270305 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,01669278 0,03267522 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,01669278 0,03264744 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,01669278 0,0326197 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,01669278 0,03259201 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,01669278 0,03256436 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,01669278 0,03253677 ! axon cargo transport GO:0008088 27 14 0,000 0,01669278 0,03250922 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,01669278 0,03248171 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,01669278 0,03245426 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,01669278 0,03242684 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,01669278 0,03239948 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,01669278 0,03237216 ! mRNA splice site selection GO:0006376 26 14 0,000 0,01669278 0,03234489 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,01669278 0,03231766 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,01669278 0,03229048 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,01669278 0,03226335 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,01669278 0,03223626 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,01669278 0,03220921 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,01669278 0,03218222 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,01669278 0,03215526 ! muscle maintenance GO:0046716 19 14 0,000 0,01669278 0,03212835 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,01669278 0,03210149 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,01669278 0,03207467 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,01669278 0,0320479 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,01669278 0,03202117 ! cell killing GO:0001906 20 14 0,000 0,01669278 0,03199449 ! release of cytochrome c from mitochondria GO:0001836 23 14 0,000 0,01669278 0,03196785 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,01669278 0,03194125 ! cilium assembly GO:0042384 20 14 0,000 0,01669278 0,0319147 ! peptide hormone secretion GO:0030072 23 14 0,000 0,01669278 0,03188819 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,01787491 0,03411808 ! positive regulation of cell size GO:0045793 20 15 0,000 0,01787491 0,03408979 ! metencephalon development GO:0022037 19 15 0,000 0,01787491 0,03406154 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,01787491 0,03403335 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,01787491 0,0340052 ! skin development GO:0043588 25 15 0,000 0,01787491 0,03397709 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,01787491 0,03394904 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,01787491 0,03392103 ! lipid phosphorylation GO:0046834 23 15 0,000 0,01787491 0,03389306 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,01787491 0,03386514 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,01787491 0,03383727 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,01787491 0,03380944 ! bile acid metabolic process GO:0008206 22 15 0,000 0,01787491 0,03378166 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,01787491 0,03375393 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,01787491 0,03372624 ! adult walking behavior GO:0007628 25 15 0,000 0,01787491 0,03369859 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,01787491 0,03367099 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,01787491 0,03364344 ! myoblast differentiation GO:0045445 27 15 0,000 0,01787491 0,03361593 ! centrosome cycle GO:0007098 16 15 0,000 0,01787491 0,03358847 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,01787491 0,03356105 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,01787491 0,03353367 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,01787491 0,03350634 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,01787491 0,03347906 ! cerebral cortex development GO:0021987 29 15 0,000 0,01787491 0,03345182 ! response to osmotic stress GO:0006970 22 15 0,000 0,01787491 0,03342462 ! vesicle coating GO:0006901 25 15 0,000 0,01787491 0,03339747 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,01787491 0,03337036 ! DNA integration GO:0015074 22 15 0,000 0,01787491 0,0333433 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,01787491 0,03331628 ! peptide secretion GO:0002790 27 15 0,000 0,01787491 0,0332893 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,01787491 0,03326237 ! regulation of vasodilation GO:0042312 24 15 0,000 0,01787491 0,03323548 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,01787491 0,03320863 ! neuron recognition GO:0008038 22 15 0,000 0,01787491 0,03318183 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,01787491 0,03315507 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,01787491 0,03312835 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,01787491 0,03310168 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,01787491 0,03307505 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,01787491 0,03304846 ! biomineral formation GO:0031214 18 15 0,000 0,01787491 0,03302191 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,01787491 0,03299541 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,01787491 0,03296895 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,01787491 0,03294254 ! dopamine metabolic process GO:0042417 30 15 0,000 0,01787491 0,03291616 ! organic cation transport GO:0015695 19 15 0,000 0,01787491 0,03288983 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,01787491 0,03286354 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,01787491 0,03283729 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,01787491 0,03281108 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,01787491 0,03278492 ! defense response to virus GO:0051607 27 15 0,000 0,01787491 0,03275879 ! peptide hormone processing GO:0016486 19 15 0,000 0,01787491 0,03273271 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,01787491 0,03270667 ! protein secretion GO:0009306 27 16 0,000 0,01905568 0,03483948 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,01905568 0,03481181 ! hormone secretion GO:0046879 25 16 0,000 0,01905568 0,03478418 ! bone remodeling GO:0046849 24 16 0,000 0,01905568 0,0347566 ! endothelial cell migration GO:0043542 22 16 0,000 0,01905568 0,03472906 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,01905568 0,03470156 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,01905568 0,03467411 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,01905568 0,0346467 ! glial cell development GO:0021782 24 16 0,000 0,01905568 0,03461933 ! patterning of blood vessels GO:0001569 24 16 0,000 0,01905568 0,034592 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,01905568 0,03456472 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,01905568 0,03453749 ! protein polyubiquitination GO:0000209 26 16 0,000 0,01905568 0,03451029 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,01905568 0,03448314 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,01905568 0,03445603 ! fructose metabolic process GO:0006000 20 16 0,000 0,01905568 0,03442896 ! regulation of protein binding GO:0043393 27 16 0,000 0,01905568 0,03440194 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,01905568 0,03437496 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,01905568 0,03434802 ! protein export from nucleus GO:0006611 24 16 0,000 0,01905568 0,03432112 ! negative regulation of immune response GO:0050777 28 16 0,000 0,01905568 0,03429426 ! DNA replication initiation GO:0006270 25 16 0,000 0,01905568 0,03426745 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,01905568 0,03424068 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,01905568 0,03421395 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,01905568 0,03418726 ! diencephalon development GO:0021536 25 16 0,000 0,01905568 0,03416062 ! oogenesis GO:0048477 23 16 0,000 0,01905568 0,03413401 ! neural crest cell migration GO:0001755 24 16 0,000 0,01905568 0,03410745 ! G1 phase GO:0051318 27 16 0,000 0,01905568 0,03408093 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,01905568 0,03405444 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,01905568 0,034028 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,01905568 0,03400161 ! steroid catabolic process GO:0006706 22 16 0,000 0,01905568 0,03397525 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,01905568 0,03394893 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,01905568 0,03392266 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,01905568 0,03389642 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,01905568 0,03387022 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,01905568 0,03384407 ! sperm-egg recognition GO:0035036 16 16 0,000 0,01905568 0,03381796 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,01905568 0,03379188 ! nerve development GO:0021675 18 16 0,000 0,01905568 0,03376585 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,01905568 0,03373985 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,01905568 0,0337139 ! negative regulation of translation GO:0017148 22 16 0,000 0,01905568 0,03368799 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,02023511 0,03574558 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,02023511 0,03571815 ! negative regulation of defense response GO:0031348 19 17 0,000 0,02023511 0,03569076 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,02023511 0,03566341 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,02023511 0,0356361 ! glycerol metabolic process GO:0006071 20 17 0,000 0,02023511 0,03560883 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,02023511 0,03558161 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,02023511 0,03555443 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,02023511 0,03552729 ! signal complex assembly GO:0007172 29 17 0,000 0,02023511 0,03550019 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,02023511 0,03547313 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,02023511 0,03544611 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,02023511 0,03541914 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,02023511 0,0353922 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,02023511 0,03536531 ! memory GO:0007613 25 17 0,000 0,02023511 0,03533846 ! keratinization GO:0031424 17 17 0,000 0,02023511 0,03531164 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,02023511 0,03528487 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,02023511 0,03525814 ! retinoid metabolic process GO:0001523 22 17 0,000 0,02023511 0,03523145 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,02023511 0,0352048 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,02023511 0,03517819 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,02023511 0,03515162 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,02023511 0,03512509 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,02023511 0,0350986 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,02023511 0,03507215 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 0,000 0,02023511 0,03504574 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,02023511 0,03501937 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,02023511 0,03499304 ! membrane budding GO:0006900 29 17 0,000 0,02023511 0,03496675 ! heme metabolic process GO:0042168 27 17 0,000 0,02023511 0,0349405 ! actin filament bundle formation GO:0051017 26 17 0,000 0,02023511 0,03491429 ! neuromuscular junction development GO:0007528 23 17 0,000 0,02023511 0,03488812 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,02023511 0,03486198 ! body fluid secretion GO:0007589 27 17 0,000 0,02023511 0,03483589 ! stem cell differentiation GO:0048863 36 17 0,000 0,02023511 0,03480983 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,02023511 0,03478382 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,02023511 0,03475784 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,02023511 0,0347319 ! sensory perception of pain GO:0019233 23 17 0,000 0,02023511 0,034706 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,02023511 0,03468014 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,02023511 0,03465432 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,02023511 0,03462853 ! synaptogenesis GO:0007416 24 17 0,000 0,02023511 0,03460279 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,02023511 0,03457708 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,02023511 0,03455141 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,02023511 0,03452578 ! cell-cell junction organization GO:0045216 25 17 0,000 0,02023511 0,03450018 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,02023511 0,03447463 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,02023511 0,03444911 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,02023511 0,03442363 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,02023511 0,03439819 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,02023511 0,03437278 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,02023511 0,03434741 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,02141318 0,03632029 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,02141318 0,03629353 ! positive regulation of translation GO:0045727 28 18 0,000 0,02141318 0,0362668 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,02141318 0,03624012 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,02141318 0,03621347 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,02141318 0,03618686 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,02141318 0,03616029 ! cAMP metabolic process GO:0046058 33 18 0,000 0,02141318 0,03613376 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,02141318 0,03610727 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,02141318 0,03608082 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,02141318 0,0360544 ! axis specification GO:0009798 26 18 0,000 0,02141318 0,03602803 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,02141318 0,03600169 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,02141318 0,0359754 ! pancreas development GO:0031016 26 18 0,000 0,02141318 0,03594914 ! apoptotic mitochondrial changes GO:0008637 29 18 0,000 0,02141318 0,03592292 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,02141318 0,03589673 ! glutamine metabolic process GO:0006541 23 18 0,000 0,02141318 0,03587059 ! response to retinoic acid GO:0032526 25 18 0,000 0,02141318 0,03584448 ! pigmentation during development GO:0048066 31 18 0,000 0,02141318 0,03581841 ! central nervous system neuron development GO:0021954 30 18 0,000 0,02141318 0,03579238 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,02141318 0,03576639 ! fucose metabolic process GO:0006004 26 18 0,000 0,02141318 0,03574043 ! response to fungus GO:0009620 19 18 0,000 0,02141318 0,03571452 ! peptide cross-linking GO:0018149 31 18 0,000 0,02141318 0,03568864 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,02141318 0,03566279 ! heart process GO:0003015 27 18 0,000 0,02141318 0,03563699 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,02141318 0,03561122 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,02141318 0,03558549 ! visual learning GO:0008542 35 18 0,000 0,02141318 0,0355598 ! somitogenesis GO:0001756 24 18 0,000 0,02141318 0,03553414 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,02141318 0,03550852 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,02141318 0,03548294 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,02141318 0,03545739 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,02141318 0,03543188 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,02141318 0,03540641 ! vitamin transport GO:0051180 24 18 0,000 0,02141318 0,03538097 ! hormone transport GO:0009914 27 18 0,000 0,02141318 0,03535558 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,02141318 0,03533021 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,02141318 0,03530489 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,02141318 0,0352796 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,02141318 0,03525434 ! cell-cell recognition GO:0009988 20 18 0,000 0,02141318 0,03522913 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,02141318 0,03520394 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,02141318 0,0351788 ! regulation of glucose import GO:0046324 21 18 0,000 0,02141318 0,03515369 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,02141318 0,03512861 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,02141318 0,03510358 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,02141318 0,03507857 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,02258991 0,03697992 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,02258991 0,03695362 ! positive regulation of fibroblast proliferation GO:0048146 27 19 0,000 0,02258991 0,03692735 ! positive regulation of ossification GO:0045778 30 19 0,000 0,02258991 0,03690113 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,02258991 0,03687494 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,02258991 0,03684878 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,02258991 0,03682267 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,02258991 0,03679659 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,02258991 0,03677055 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,02258991 0,03674454 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,02258991 0,03671858 ! regeneration GO:0031099 32 19 0,000 0,02258991 0,03669264 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,02258991 0,03666675 ! response to alkaloid GO:0043279 32 19 0,000 0,02258991 0,03664089 ! sensory perception of taste GO:0050909 23 19 0,000 0,02258991 0,03661507 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,02258991 0,03658928 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 0,000 0,02258991 0,03656354 ! smooth muscle contraction GO:0006939 36 19 0,000 0,02258991 0,03653782 ! peroxisome organization GO:0007031 29 19 0,000 0,02258991 0,03651215 ! digestive system process GO:0022600 30 19 0,000 0,02258991 0,03648651 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,02258991 0,0364609 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,02258991 0,03643533 ! response to vitamin A GO:0033189 26 19 0,000 0,02258991 0,0364098 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,02258991 0,0363843 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,02258991 0,03635884 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,02258991 0,03633342 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,02258991 0,03630803 ! response to starvation GO:0042594 30 19 0,000 0,02258991 0,03628267 ! sex determination GO:0007530 29 19 0,000 0,02258991 0,03625735 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,02258991 0,03623207 ! plasma membrane fusion GO:0045026 23 19 0,000 0,02258991 0,03620682 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,02258991 0,0361816 ! cytolysis GO:0019835 20 19 0,000 0,02258991 0,03615643 ! renal system process GO:0003014 35 19 0,000 0,02258991 0,03613128 ! vasodilation GO:0042311 33 19 0,000 0,02258991 0,03610617 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,02258991 0,0360811 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,02258991 0,03605606 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,02258991 0,03603106 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,02258991 0,03600609 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,02258991 0,03598115 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,02258991 0,03595625 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,02258991 0,03593139 ! sarcomere organization GO:0045214 23 19 0,000 0,02258991 0,03590655 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,02258991 0,03588176 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,02258991 0,03585699 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,02258991 0,03583227 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,02258991 0,03580757 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,02258991 0,03578291 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,02258991 0,03575828 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,02258991 0,03573369 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,02258991 0,03570913 ! protein stabilization GO:0050821 26 19 0,000 0,02258991 0,0356846 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,02376528 0,03751555 ! iron ion transport GO:0006826 37 20 0,000 0,02376528 0,03748982 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,02376528 0,03746412 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,02376528 0,03743846 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,02376528 0,03741284 ! response to vitamin GO:0033273 29 20 0,000 0,02376528 0,03738724 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,02376528 0,03736169 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,02376528 0,03733617 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,02376528 0,03731068 ! spinal cord development GO:0021510 31 20 0,000 0,02376528 0,03728523 ! response to ethanol GO:0045471 37 20 0,000 0,02376528 0,03725982 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,02376528 0,03723444 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 0,000 0,02376528 0,03720909 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,02376528 0,03718378 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,02376528 0,0371585 ! chromosome condensation GO:0030261 31 20 0,000 0,02376528 0,03713326 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,02376528 0,03710805 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,02376528 0,03708287 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,02376528 0,03705773 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,02376528 0,03703262 ! pallium development GO:0021543 38 20 0,000 0,02376528 0,03700755 ! DNA modification GO:0006304 28 20 0,000 0,02376528 0,03698251 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,02376528 0,03695751 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,02376528 0,03693254 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,02376528 0,0369076 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,02376528 0,03688269 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,02376528 0,03685782 ! positive regulation of B cell activation GO:0050871 31 20 0,000 0,02376528 0,03683299 ! collagen catabolic process GO:0030574 25 20 0,000 0,02376528 0,03680818 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,02376528 0,03678341 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,02376528 0,03675868 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,02376528 0,03673397 ! alditol metabolic process GO:0019400 24 20 0,000 0,02376528 0,0367093 ! actin filament-based movement GO:0030048 34 20 0,000 0,02376528 0,03668467 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,02493931 0,03847111 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,02493931 0,03844532 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,02493931 0,03841957 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,02493931 0,03839386 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 0,000 0,02493931 0,03836818 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,02493931 0,03834253 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,02493931 0,03831692 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,02493931 0,03829134 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,02493931 0,03826579 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,02493931 0,03824028 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,02493931 0,03821481 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,02493931 0,03818936 ! protein amino acid acylation GO:0043543 37 21 0,000 0,02493931 0,03816395 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,02493931 0,03813858 ! vesicle docking GO:0048278 27 21 0,000 0,02493931 0,03811324 ! phototransduction GO:0007602 25 21 0,000 0,02493931 0,03808793 ! dendrite development GO:0016358 35 21 0,000 0,02493931 0,03806266 ! visual behavior GO:0007632 39 21 0,000 0,02493931 0,03803742 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,02493931 0,03801221 ! ovarian follicle development GO:0001541 30 21 0,000 0,02493931 0,03798704 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,02493931 0,03796189 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,02493931 0,03793679 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,02493931 0,03791171 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,02493931 0,03788667 ! cell aging GO:0007569 32 21 0,000 0,02493931 0,03786167 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,02493931 0,03783669 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,02493931 0,03781175 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,02493931 0,03778684 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,02493931 0,03776196 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,02493931 0,03773712 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,02493931 0,03771231 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,02493931 0,03768753 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,02493931 0,03766279 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,02493931 0,03763807 ! fatty acid transport GO:0015908 30 21 0,000 0,02493931 0,03761339 ! immunoglobulin production GO:0002377 33 21 0,000 0,02493931 0,03758874 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,02493931 0,03756413 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,02493931 0,03753954 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,02493931 0,03751499 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,02493931 0,03749047 ! cellular response to extracellular stimulus GO:0031668 32 21 0,000 0,02493931 0,03746599 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,02493931 0,03744153 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,02493931 0,03741711 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,02493931 0,03739271 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,02493931 0,03736835 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,02493931 0,03734403 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,02493931 0,03731973 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,02493931 0,03729546 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,02493931 0,03727123 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,02493931 0,03724703 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,02493931 0,03722286 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,026112 0,03894786 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,026112 0,03892262 ! regulation of fibroblast proliferation GO:0048145 35 22 0,000 0,026112 0,03889741 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,026112 0,03887223 ! viral genome replication GO:0019079 29 22 0,000 0,026112 0,03884709 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,026112 0,03882198 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,026112 0,0387969 ! leukocyte adhesion GO:0007159 38 22 0,000 0,026112 0,03877185 ! molting cycle process GO:0022404 40 22 0,000 0,026112 0,03874684 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,026112 0,03872186 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,026112 0,03869691 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,026112 0,03867199 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,026112 0,03864711 ! vasculogenesis GO:0001570 33 22 0,000 0,026112 0,03862225 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,026112 0,03859743 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,026112 0,03857264 GO:0010810|regulation of cell-substrate adhesion, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,026112 0,03854788 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,026112 0,03852316 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,026112 0,03849846 ! lysosome organization GO:0007040 37 22 0,000 0,026112 0,0384738 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,026112 0,03844917 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,026112 0,03842457 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,026112 0,0384 ! regulation of behavior GO:0050795 38 22 0,000 0,026112 0,03837546 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,026112 0,03835096 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,026112 0,03832648 ! membrane depolarization GO:0051899 35 22 0,000 0,026112 0,03830204 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,026112 0,03827763 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,026112 0,03825325 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,026112 0,0382289 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,026112 0,03820458 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,026112 0,03818029 ! blastocyst development GO:0001824 37 22 0,000 0,026112 0,03815604 ! neural tube closure GO:0001843 33 22 0,000 0,026112 0,03813181 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,026112 0,03810762 ! protein tetramerization GO:0051262 39 22 0,000 0,026112 0,03808345 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,02728334 0,0397666 ! neuron fate commitment GO:0048663 32 23 0,000 0,02728334 0,03974141 ! embryonic pattern specification GO:0009880 31 23 0,000 0,02728334 0,03971626 ! positive regulation of cell adhesion GO:0045785 37 23 0,000 0,02728334 0,03969114 ! myelination GO:0042552 35 23 0,000 0,02728334 0,03966605 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,02728334 0,03964099 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,02728334 0,03961597 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,02728334 0,03959097 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,02728334 0,03956601 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,02728334 0,03954108 ! vesicle targeting GO:0006903 32 23 0,000 0,02728334 0,03951618 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,02728334 0,03949131 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,02728334 0,03946647 ! osteoblast differentiation GO:0001649 40 23 0,000 0,02728334 0,03944167 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,02728334 0,03941689 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,02728334 0,03939215 ! interaction with host GO:0051701 37 23 0,000 0,02728334 0,03936743 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,02728334 0,03934275 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,02728334 0,0393181 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,02728334 0,03929348 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,02728334 0,03926889 ! negative regulation of phosphorylation GO:0042326 41 23 0,000 0,02728334 0,03924433 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,02728334 0,03921981 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,02728334 0,03919531 ! cell fate determination GO:0001709 45 23 0,000 0,02728334 0,03917084 ! pentose metabolic process GO:0019321 31 23 0,000 0,02728334 0,03914641 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,02728334 0,039122 ! spermatid development GO:0007286 33 23 0,000 0,02728334 0,03909763 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,02728334 0,03907328 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,02728334 0,03904897 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,02728334 0,03902468 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,02728334 0,03900043 ! telomere organization GO:0032200 32 23 0,000 0,02728334 0,03897621 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,02728334 0,03895201 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,02728334 0,03892785 ! regulation of amine transport GO:0051952 38 23 0,000 0,02728334 0,03890371 ! liver development GO:0001889 40 23 0,000 0,02728334 0,03887961 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,02845334 0,04052179 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,02845334 0,04049672 ! initiation of viral infection GO:0019059 42 24 0,000 0,02845334 0,04047167 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,02845334 0,04044666 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,02845334 0,04042168 ! superoxide metabolic process GO:0006801 32 24 0,000 0,02845334 0,04039672 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,02845334 0,0403718 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! insulin receptor signaling pathway GO:0008286 40 24 0,000 0,02845334 0,04034691 ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,02845334 0,04032205 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,02845334 0,04029722 ! sperm motility GO:0030317 27 24 0,000 0,02845334 0,04027243 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,02845334 0,04024766 ! vacuole organization GO:0007033 39 24 0,000 0,02845334 0,04022292 ! receptor metabolic process GO:0043112 37 24 0,000 0,02845334 0,04019821 ! neural crest cell development GO:0014032 39 24 0,000 0,02845334 0,04017354 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,02845334 0,04014889 ! primary neural tube formation GO:0014020 35 24 0,000 0,02845334 0,04012428 ! negative regulation of cell development GO:0010721 56 24 0,000 0,02845334 0,04009969 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,02845334 0,04007513 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,02845334 0,04005061 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,02845334 0,04002611 ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,02845334 0,04000165 ! glutathione metabolic process GO:0006749 29 24 0,000 0,02845334 0,03997721 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,02845334 0,0399528 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,02845334 0,03992843 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,02845334 0,03990408 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,02962201 0,04151774 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,02962201 0,04149246 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,02962201 0,0414672 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,02962201 0,04144198 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,02962201 0,04141679 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,02962201 0,04139162 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 0,000 0,02962201 0,04136649 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,02962201 0,04134139 ! peptide transport GO:0015833 43 25 0,000 0,02962201 0,04131632 ! male gonad development GO:0008584 33 25 0,000 0,02962201 0,04129128 ! iron ion homeostasis GO:0055072 39 25 0,000 0,02962201 0,04126627 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,02962201 0,04124129 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,02962201 0,04121634 ! phospholipid transport GO:0015914 35 25 0,000 0,02962201 0,04119142 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,02962201 0,04116653 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,02962201 0,04114167 ! detection of light stimulus GO:0009583 30 25 0,000 0,02962201 0,04111685 ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,02962201 0,04109205 ! leukocyte proliferation GO:0070661 39 25 0,000 0,02962201 0,04106728 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,02962201 0,04104254 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,03078933 0,04263423 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,03078933 0,04260858 ! translational initiation GO:0006413 43 26 0,000 0,03078933 0,04258295 ! regulation of pH GO:0006885 36 26 0,000 0,03078933 0,04255736 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 0,000 0,03078933 0,0425318 ! circadian rhythm GO:0007623 42 26 0,000 0,03078933 0,04250627 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,03078933 0,04248078 ! post-embryonic development GO:0009791 42 26 0,000 0,03078933 0,04245531 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,03078933 0,04242987 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,03078933 0,04240446 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,03078933 0,04237909 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,03078933 0,04235374 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,03078933 0,04232842 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,03078933 0,04230314 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,03078933 0,04227788 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,03078933 0,04225266 ! regulation of coagulation GO:0050818 39 26 0,000 0,03078933 0,04222746 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,03195531 0,04380049 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,03195531 0,0437744 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,03195531 0,04374834 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,03195531 0,04372232 ! membrane docking GO:0022406 39 27 0,000 0,03195531 0,04369632 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,03195531 0,04367036 ! catechol metabolic process GO:0009712 43 27 0,000 0,03195531 0,04364443 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,03195531 0,04361853 ! acute-phase response GO:0006953 42 27 0,000 0,03195531 0,04359266 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,03195531 0,04356682 ! myofibril assembly GO:0030239 36 27 0,000 0,03195531 0,04354101 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,03195531 0,04351523 ! response to ionizing radiation GO:0010212 47 27 0,000 0,03195531 0,04348948 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,03195531 0,04346376 ! natural killer cell activation GO:0030101 35 27 0,000 0,03195531 0,04343807 ! lipid oxidation GO:0034440 38 27 0,000 0,03195531 0,04341241 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,03195531 0,04338679 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,03195531 0,04336119 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,03195531 0,04333562 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,03195531 0,04331009 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,03195531 0,04328458 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,03195531 0,0432591 ! gene silencing GO:0016458 41 27 0,000 0,03195531 0,04323366 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,03311996 0,04478302 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,03311996 0,0447567 ! phenol metabolic process GO:0018958 44 28 0,000 0,03311996 0,04473042 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,03311996 0,04470417 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,03311996 0,04467795 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,03311996 0,04465176 ! cell junction assembly GO:0034329 56 28 0,000 0,03311996 0,04462561 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,03311996 0,04459948 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,03311996 0,04457338 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,03311996 0,04454731 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,03311996 0,04452128 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,03311996 0,04449527 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,03311996 0,0444693 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,03311996 0,04444335 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,03311996 0,04441744 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,03311996 0,04439156 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,03311996 0,0443657 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,03311996 0,04433988 ! mesoderm formation GO:0001707 46 28 0,000 0,03311996 0,04431408 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,03311996 0,04428832 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,03311996 0,04426258 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,03311996 0,04423688 ! ensheathment of neurons GO:0007272 43 28 0,000 0,03311996 0,04421121 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,03311996 0,04418556 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,03311996 0,04415995 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,03311996 0,04413436 ! neural tube formation GO:0001841 41 28 0,000 0,03311996 0,04410881 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,03311996 0,04408328 ! placenta development GO:0001890 37 28 0,000 0,03311996 0,04405778 ! regulation of B cell activation GO:0050864 42 28 0,000 0,03311996 0,04403232 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,03428327 0,04555259 ! regulation of innate immune response GO:0045088 38 29 0,000 0,03428327 0,04552629 ! ovulation cycle process GO:0022602 41 29 0,000 0,03428327 0,04550002 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,03428327 0,04547378 ! protein targeting to membrane GO:0006612 53 29 0,000 0,03428327 0,04544757 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,03428327 0,04542139 ! mismatch repair GO:0006298 34 29 0,000 0,03428327 0,04539524 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,03428327 0,04536912 ! muscle cell development GO:0055001 38 29 0,000 0,03428327 0,04534303 ! formation of primary germ layer GO:0001704 48 29 0,000 0,03428327 0,04531697 ! telencephalon development GO:0021537 52 29 0,000 0,03428327 0,04529094 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,03428327 0,04526494 ! eye morphogenesis GO:0048592 51 29 0,000 0,03428327 0,04523897 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,03428327 0,04521303 ! tissue homeostasis GO:0001894 42 29 0,000 0,03428327 0,04518712 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,03544525 0,04669192 ! collagen metabolic process GO:0032963 40 30 0,000 0,03544525 0,04666519 ! organic anion transport GO:0015711 51 30 0,000 0,03544525 0,04663849 ! cholesterol transport GO:0030301 46 30 0,000 0,03544525 0,04661183 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,03544525 0,04658519 ! spliceosome assembly GO:0000245 49 30 0,000 0,03544525 0,04655859 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,03544525 0,04653201 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,03544525 0,04650547 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,03544525 0,04647895 ! ceramide metabolic process GO:0006672 43 30 0,000 0,03544525 0,04645247 ! ovulation cycle GO:0042698 43 30 0,000 0,03544525 0,04642602 ! hindbrain development GO:0030902 45 30 0,000 0,03544525 0,04639959 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,03544525 0,0463732 ! adult locomotory behavior GO:0008344 47 30 0,000 0,03544525 0,04634684 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,03544525 0,0463205 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,03544525 0,0462942 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,03544525 0,04626793 ! response to heat GO:0009408 41 30 0,000 0,03544525 0,04624168 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,03544525 0,04621547 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,03544525 0,04618928 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,0366059 0,04767473 ! negative regulation of secretion GO:0051048 49 31 0,000 0,0366059 0,04764775 ! mammary gland development GO:0030879 57 31 0,000 0,0366059 0,0476208 ! glial cell differentiation GO:0010001 55 31 0,000 0,0366059 0,04759388 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,0366059 0,04756699 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,0366059 0,04754014 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,0366059 0,04751331 ! odontogenesis GO:0042476 50 31 0,000 0,0366059 0,04748651 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,0366059 0,04745974 ! segmentation GO:0035282 41 31 0,000 0,0366059 0,047433 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,0366059 0,04740629 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,0366059 0,04737962 ! metanephros development GO:0001656 58 31 0,000 0,0366059 0,04735297 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,0366059 0,04732635 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,0366059 0,04729976 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,0366059 0,04727321 ! cell fate specification GO:0001708 37 31 0,000 0,0366059 0,04724668 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,0366059 0,04722018 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,0366059 0,04719371 ! RNA modification GO:0009451 40 31 0,000 0,0366059 0,04716727 ! regulation of muscle development GO:0048634 48 32 0,000 0,03776522 0,04863383 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,03776522 0,04860661 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,03776522 0,04857943 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,03776522 0,04855227 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,03776522 0,04852515 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,03776522 0,04849805 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,03776522 0,04847099 ! peripheral nervous system development GO:0007422 53 32 0,000 0,03776522 0,04844396 ! regulation of protein stability GO:0031647 48 32 0,000 0,03776522 0,04841695 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,03776522 0,04838998 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,03776522 0,04836304 ! cytokine production GO:0001816 44 32 0,000 0,03776522 0,04833612 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,03776522 0,04830924 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,03776522 0,04828239 ! vesicle localization GO:0051648 47 32 0,000 0,03776522 0,04825556 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,03892321 0,0497076 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,03892321 0,04968002 ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,03892321 0,04965246 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,03892321 0,04962494 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,03892321 0,04959745 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,03892321 0,04956998 ! ear morphogenesis GO:0042471 42 33 0,000 0,03892321 0,04954255 ! actomyosin structure organization GO:0031032 43 33 0,000 0,03892321 0,04951515 ! cell junction organization GO:0034330 63 33 0,000 0,03892321 0,04948778 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,03892321 0,04946044 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,03892321 0,04943313 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,03892321 0,04940584 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 0,000 0,03892321 0,04937859 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,03892321 0,04935137 ! female gonad development GO:0008585 49 33 0,000 0,03892321 0,04932418 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,03892321 0,04929702 ! positive regulation of cell development GO:0010720 54 33 0,000 0,03892321 0,04926989 ! lipid homeostasis GO:0055088 55 33 0,000 0,03892321 0,04924279 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,03892321 0,04921572 ! regulation of proteolysis GO:0030162 50 33 0,000 0,03892321 0,04918868 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,03892321 0,04916166 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,03892321 0,04913468 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,03892321 0,04910773 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,03892321 0,04908081 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,04007988 0,05051163 ! mRNA catabolic process GO:0006402 48 34 0,000 0,04007988 0,05048396 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,04007988 0,05045633 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,04007988 0,05042873 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,04007988 0,05040116 ! feeding behavior GO:0007631 45 34 0,000 0,04007988 0,05037362 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,04007988 0,0503461 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,04007988 0,05031862 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,04007988 0,05029117 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,04007988 0,05026375 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,04007988 0,05023636 ! neuron migration GO:0001764 46 34 0,000 0,04007988 0,050209 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,04007988 0,05018166 ! female gamete generation GO:0007292 43 34 0,000 0,04007988 0,05015436 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,04007988 0,05012709 ! polyol metabolic process GO:0019751 44 34 0,000 0,04007988 0,05009985 ! aerobic respiration GO:0009060 47 34 0,000 0,04007988 0,05007263 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,04007988 0,05004545 ! cellular response to insulin stimulus GO:0032869 52 34 0,000 0,04007988 0,05001829 ! embryonic organ development GO:0048568 45 34 0,000 0,04007988 0,04999117 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,04007988 0,04996407 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,04123521 0,05137648 ! Notch signaling pathway GO:0007219 56 35 0,000 0,04123521 0,05134867 ! regulation of intracellular protein transport GO:0033157 59 35 0,000 0,04123521 0,05132088 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,04123521 0,05129313 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,04123521 0,0512654 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,04123521 0,0512377 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,04123521 0,05121004 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,04123521 0,0511824 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,04123521 0,0511548 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,04123521 0,05112722 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,04123521 0,05109967 ! glycogen metabolic process GO:0005977 48 35 0,000 0,04123521 0,05107215 ! pigment metabolic process GO:0042440 61 35 0,000 0,04123521 0,05104467 ! positive regulation of leukocyte proliferation GO:0070665 50 35 0,000 0,04123521 0,05101721 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! protein homooligomerization GO:0051260 52 35 0,000 0,04123521 0,05098978 ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,04238923 0,05238862 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 0,000 0,04238923 0,05236048 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,04238923 0,05233238 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,04238923 0,0523043 ! negative regulation of binding GO:0051100 58 36 0,000 0,04238923 0,05227626 ! organic ether metabolic process GO:0018904 46 36 0,000 0,04238923 0,05224824 ! tissue remodeling GO:0048771 62 36 0,000 0,04238923 0,05222026 ! neural tube development GO:0021915 50 36 0,000 0,04238923 0,0521923 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,04238923 0,05216438 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,04238923 0,05213648 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,04238923 0,05210862 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,04238923 0,05208078 ! glucan metabolic process GO:0044042 49 36 0,000 0,04238923 0,05205297 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,04354192 0,05343992 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,04354192 0,05341142 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,04354192 0,05338295 ! learning GO:0007612 67 37 0,000 0,04354192 0,05335451 ! ion transmembrane transport GO:0034220 56 37 0,000 0,04354192 0,0533261 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,04354192 0,05329772 ! regulation of protein secretion GO:0050708 51 37 0,000 0,04354192 0,05326937 ! amino acid activation GO:0043038 52 37 0,000 0,04354192 0,05324105 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,04354192 0,05321276 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,04469328 0,05459084 ! gliogenesis GO:0042063 71 38 0,000 0,04469328 0,05456187 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,04469328 0,05453292 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,04469328 0,05450401 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,04469328 0,05447512 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,04469328 0,05444627 ! phagocytosis GO:0006909 60 38 0,000 0,04469328 0,05441745 ! mesenchymal cell development GO:0014031 64 38 0,000 0,04469328 0,05438865 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 0,000 0,04469328 0,05435989 ! maintenance of location in cell GO:0051651 69 38 0,000 0,04469328 0,05433116 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,04584333 0,05569977 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,04584333 0,05567036 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,04584333 0,05564098 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,04584333 0,05561164 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,04584333 0,05558232 ! regulation of epithelial cell proliferation GO:0050678 71 39 0,000 0,04584333 0,05555304 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,04584333 0,05552378 ! male sex differentiation GO:0046661 53 39 0,000 0,04584333 0,05549456 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,04584333 0,05546537 ! chromatin remodeling GO:0006338 68 39 0,000 0,04584333 0,05543621 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,04584333 0,05540708 ! JNK cascade GO:0007254 54 39 0,000 0,04584333 0,05537798 ! developmental growth GO:0048589 62 39 0,000 0,04584333 0,05534891 ! cell growth GO:0016049 61 39 0,000 0,04584333 0,05531987 ! synapse organization GO:0050808 55 39 0,000 0,04584333 0,05529086 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,04699206 0,05664662 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,04699206 0,05661694 ! regulation of tube size GO:0035150 60 40 0,000 0,04699206 0,0565873 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,04699206 0,05655769 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,04699206 0,05652811 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,04699206 0,05649856 ! peptide metabolic process GO:0006518 56 40 0,000 0,04699206 0,05646904 ! induction of apoptosis by intracellular signals GO:0008629 67 40 0,000 0,04699206 0,05643955 ! inner ear development GO:0048839 57 40 0,000 0,04699206 0,0564101 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,04699206 0,05638067 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,04699206 0,05635127 ! double-strand break repair GO:0006302 67 40 0,000 0,04699206 0,05632191 ! B cell differentiation GO:0030183 62 40 0,000 0,04699206 0,05629257 ! epidermal cell differentiation GO:0009913 53 40 0,000 0,04699206 0,05626327 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,04699206 0,056234 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,04699206 0,05620475 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,04699206 0,05617554 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,04813947 0,05751729 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,04813947 0,05748743 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,04813947 0,0574576 ! glucose transport GO:0015758 52 41 0,000 0,04813947 0,0574278 ! endosome transport GO:0016197 71 41 0,000 0,04813947 0,05739803 ! striated muscle contraction GO:0006941 62 41 0,000 0,04813947 0,05736829 ! positive regulation of DNA binding GO:0043388 57 41 0,000 0,04813947 0,05733858 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,04813947 0,0573089 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,04813947 0,05727925 ! biopolymer methylation GO:0043414 62 41 0,000 0,04813947 0,05724963 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,04813947 0,05722005 ! mitochondrial transport GO:0006839 60 42 0,000 0,04928557 0,05855207 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,04928557 0,05852185 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 0,000 0,04928557 0,05849165 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,04928557 0,05846148 ! cellular component disassembly GO:0022411 64 42 0,000 0,04928557 0,05843135 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,04928557 0,05840124 ! hexose transport GO:0008645 54 42 0,000 0,04928557 0,05837117 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,04928557 0,05834113 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,04928557 0,05831112 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,04928557 0,05828114 ! excretion GO:0007588 63 42 0,000 0,04928557 0,05825119 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,04928557 0,05822127 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,04928557 0,05819138 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,04928557 0,05816153 ! regulation of cell shape GO:0008360 78 42 0,000 0,04928557 0,0581317 ! positive regulation of binding GO:0051099 59 43 0,000 0,05043035 0,05945147 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,05043035 0,05942101 ! leukocyte migration GO:0050900 60 43 0,000 0,05043035 0,05939059 ! neuromuscular process GO:0050905 79 43 0,000 0,05043035 0,05936019 ! activation of caspase activity GO:0006919 65 43 0,000 0,05043035 0,05932983 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,05043035 0,0592995 ! tRNA processing GO:0008033 49 43 0,000 0,05043035 0,05926919 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,05043035 0,05923892 ! vesicle organization GO:0016050 79 43 0,000 0,05043035 0,05920868 ! response to insulin stimulus GO:0032868 63 43 0,000 0,05043035 0,05917848 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,05043035 0,0591483 ! methylation GO:0032259 64 43 0,000 0,05043035 0,05911815 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,05157382 0,06042781 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,05157382 0,06039704 ! glycolysis GO:0006096 53 44 0,000 0,05157382 0,06036631 ! regulation of action potential GO:0001508 71 44 0,000 0,05157382 0,0603356 ! regulation of ion transport GO:0043269 57 44 0,000 0,05157382 0,06030493 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,05157382 0,06027428 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,05157382 0,06024367 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,05157382 0,06021309 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,05157382 0,06018254 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,05157382 0,06015202 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,05157382 0,06012154 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,05157382 0,06009108 ! regulation of mast cell proliferation GO:0070666 64 44 0,000 0,05157382 0,06006065 ! RNA catabolic process GO:0006401 64 45 0,000 0,05271598 0,06135969 ! positive regulation of defense response GO:0031349 59 45 0,000 0,05271598 0,06132866 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,05271598 0,06129765 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,05271598 0,06126668 ! cell recognition GO:0008037 58 45 0,000 0,05271598 0,06123574 ! cell maturation GO:0048469 60 45 0,000 0,05271598 0,06120482 ! protein amino acid autophosphorylation GO:0046777 80 45 0,000 0,05271598 0,06117394 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,05385683 0,06246632 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,05385683 0,06243483 ! cell redox homeostasis GO:0045454 63 46 0,000 0,05385683 0,06240338 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,05385683 0,06237196 ! regulation of ossification GO:0030278 71 46 0,000 0,05385683 0,06234057 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,05385683 0,06230921 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,05499637 0,0635956 ! viral infectious cycle GO:0019058 71 47 0,000 0,05499637 0,06356364 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,05499637 0,06353172 ! endocrine system development GO:0035270 83 47 0,000 0,05499637 0,06349982 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,05499637 0,06346796 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,05499637 0,06343613 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,05499637 0,06340433 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,05499637 0,06337257 ! regulation of leukocyte proliferation GO:0070663 71 47 0,000 0,05499637 0,06334083 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,05499637 0,06330913 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,05499637 0,06327746 ! chloride transport GO:0006821 67 48 0,000 0,0561346 0,06455479 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,0561346 0,06452253 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 0,000 0,0561346 0,0644903 ! response to temperature stimulus GO:0009266 62 48 0,000 0,0561346 0,0644581 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,0561346 0,06442594 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,0561346 0,06439381 ! gastrulation GO:0007369 73 48 0,000 0,0561346 0,0643617 ! heart morphogenesis GO:0003007 65 48 0,000 0,0561346 0,06432964 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,0561346 0,0642976 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,0561346 0,06426559 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,0561346 0,06423362 ! regulation of endocytosis GO:0030100 63 48 0,000 0,0561346 0,06420168 ! nuclear export GO:0051168 69 48 0,000 0,0561346 0,06416977 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,0561346 0,06413789 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,0561346 0,06410605 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,05727153 0,06537197 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,05727153 0,06533954 ! sensory perception of smell GO:0007608 61 49 0,000 0,05727153 0,06530714 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,05727153 0,06527478 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,05727153 0,06524245 ! RNA elongation GO:0006354 62 49 0,000 0,05727153 0,06521015 ! regulation of intracellular transport GO:0032386 78 49 0,000 0,05727153 0,06517789 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,05727153 0,06514565 ! germ cell development GO:0007281 68 49 0,000 0,05727153 0,06511345 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,05727153 0,06508128 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,05727153 0,06504914 ! cartilage development GO:0051216 70 49 0,000 0,05727153 0,06501703 ! maintenance of location GO:0051235 84 49 0,000 0,05727153 0,06498496 ! regulation of actin filament length GO:0030832 72 50 0,000 0,05840715 0,06624085 ! ear development GO:0043583 72 50 0,000 0,05840715 0,0662082 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,05840715 0,06617559 ! membrane fusion GO:0006944 80 50 0,000 0,05840715 0,066143 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,05840715 0,06611045 ! lipid modification GO:0030258 73 50 0,000 0,05840715 0,06607793 ! positive regulation of growth GO:0045927 67 50 0,000 0,05840715 0,06604545 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,05840715 0,06601299 ! proton transport GO:0015992 75 50 0,000 0,05840715 0,06598057 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,05840715 0,06594818 ! positive regulation of secretion GO:0051047 71 51 0,000 0,05954147 0,06719596 ! hydrogen transport GO:0006818 77 51 0,000 0,05954147 0,06716301 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,05954147 0,06713009 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 0,000 0,05954147 0,06709719 ! positive regulation of cell migration GO:0030335 92 51 0,000 0,05954147 0,06706434 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,05954147 0,06703151 ! adult behavior GO:0030534 80 51 0,000 0,05954147 0,06699872 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,05954147 0,06696595 ! transition metal ion transport GO:0000041 74 52 0,000 0,06067448 0,0682069 ! regulation of cellular component size GO:0032535 74 52 0,000 0,06067448 0,06817358 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,06067448 0,06814029 ! aging GO:0007568 79 52 0,000 0,06067448 0,06810704 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,06067448 0,06807381 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,0618062 0,06930973 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,0618062 0,06927596 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,0618062 0,06924221 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,0618062 0,0692085 ! kidney development GO:0001822 90 53 0,000 0,0618062 0,06917483 ! single fertilization GO:0007338 59 53 0,000 0,0618062 0,06914118 ! cell projection assembly GO:0030031 76 53 0,000 0,0618062 0,06910757 ! amino acid transport GO:0006865 84 54 0,000 0,06293662 0,07033733 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,06293662 0,07030317 ! glucose catabolic process GO:0006007 66 54 0,000 0,06293662 0,07026904 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,06293662 0,07023495 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,06293662 0,07020089 ! DNA catabolic process GO:0006308 67 54 0,000 0,06293662 0,07016686 ! detection of external stimulus GO:0009581 66 54 0,000 0,06293662 0,07013286 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,06293662 0,0700989 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,06293662 0,07006497 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,06293662 0,07003107 ! exocytosis GO:0006887 74 55 0,000 0,06406574 0,071253 ! mesoderm development GO:0007498 76 55 0,000 0,06406574 0,07121856 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,06406574 0,07118416 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,06406574 0,07114979 ! DNA damage response, signal transduction GO:0042770 96 56 0,000 0,06519357 0,07236738 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,06519357 0,07233247 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,06519357 0,07229759 ! positive regulation of cell motion GO:0051272 99 56 0,000 0,06519357 0,07226275 ! negative regulation of protein kinase activity GO:0006469 99 57 0,000 0,0663201 0,07347603 ! carbohydrate transport GO:0008643 74 57 0,000 0,0663201 0,07344065 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,0663201 0,07340531 GO:0048609|reproductive process in a multicellular organism, ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,0663201 0,07337 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,0663201 0,07333473 ! camera-type eye development GO:0043010 88 57 0,000 0,0663201 0,07329949 ! secondary metabolic process GO:0019748 84 57 0,000 0,0663201 0,07326428 ! response to peptide hormone stimulus GO:0043434 84 57 0,000 0,0663201 0,07322911 ! developmental maturation GO:0021700 75 57 0,000 0,0663201 0,07319397 ! gonad development GO:0008406 79 57 0,000 0,0663201 0,07315886 ! negative regulation of kinase activity GO:0033673 100 58 0,000 0,06744534 0,07436447 ! viral reproductive process GO:0022415 87 58 0,000 0,06744534 0,07432883 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,06744534 0,07429324 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,06744534 0,07425767 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,06744534 0,07422214 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,06856928 0,07542293 ! activation of MAPK activity GO:0000187 84 59 0,000 0,06856928 0,07538688 ! lung development GO:0030324 94 59 0,000 0,06856928 0,07535086 ! actin filament organization GO:0007015 95 59 0,000 0,06856928 0,07531488 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,06856928 0,07527893 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,06856928 0,07524301 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,06969194 0,07643847 ! phosphoinositide metabolic process GO:0030384 87 60 0,000 0,06969194 0,07640203 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,06969194 0,07636563 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,06969194 0,07632927 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,06969194 0,07629294 ! regulation of heart contraction GO:0008016 91 60 0,000 0,06969194 0,07625664 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,06969194 0,07622038 ! fertilization GO:0009566 68 60 0,000 0,06969194 0,07618416 ! regulation of homeostatic process GO:0032844 105 60 0,000 0,06969194 0,07614796 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,07081331 0,07733647 ! cell-matrix adhesion GO:0007160 114 61 0,000 0,07081331 0,07729977 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,07081331 0,0772631 ! urogenital system development GO:0001655 101 61 0,000 0,07081331 0,07722646 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,07081331 0,07718986 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,07081331 0,0771533 ! extracellular matrix organization GO:0030198 103 61 0,000 0,07081331 0,07711677 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,07081331 0,07708027 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! negative regulation of transferase activity GO:0051348 105 61 0,000 0,07081331 0,07704381 ! amine catabolic process GO:0009310 90 62 0,000 0,07193339 0,07822544 ! neurotransmitter transport GO:0006836 81 62 0,000 0,07193339 0,07818847 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,07193339 0,07815153 ! negative regulation of cell growth GO:0030308 106 62 0,000 0,07193339 0,07811463 ! respiratory tube development GO:0030323 99 62 0,000 0,07193339 0,07807777 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,07193339 0,07804094 ! regulation of transcription factor activity GO:0051090 97 63 0,000 0,07305218 0,07921736 GO:0090046|regulation of transcription regulator activity, ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,07305218 0,07918003 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 0,000 0,07305218 0,07914273 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 0,000 0,07305218 0,07910547 ! viral reproduction GO:0016032 92 63 0,000 0,07305218 0,07906825 ! regulation of lipase activity GO:0060191 109 63 0,000 0,07305218 0,07903106 ! cell cycle checkpoint GO:0000075 108 64 0,000 0,07416969 0,0802023 ! negative regulation of cell size GO:0045792 108 64 0,000 0,07416969 0,08016461 ! appendage morphogenesis GO:0035107 93 64 0,000 0,07416969 0,08012696 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,07416969 0,08008934 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,07416969 0,08005176 ! hexose catabolic process GO:0019320 82 64 0,000 0,07416969 0,08001421 ! respiratory system development GO:0060541 100 64 0,000 0,07416969 0,0799767 ! adaptive immune response GO:0002250 94 64 0,000 0,07416969 0,07993922 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 90 65 0,000 0,07528592 0,08110427 ! regulation of caspase activity GO:0043281 97 65 0,000 0,07528592 0,0810663 ! appendage development GO:0048736 94 65 0,000 0,07528592 0,08102837 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 0,000 0,07528592 0,08099047 ! defense response to bacterium GO:0042742 73 65 0,000 0,07528592 0,0809526 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,07528592 0,08091477 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,07528592 0,08087698 ! activation of immune response GO:0002253 83 65 0,000 0,07528592 0,08083922 ! protein oligomerization GO:0051259 100 65 0,000 0,07528592 0,0808015 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,07640087 0,08195988 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,07640087 0,08192167 ! antigen processing and presentation GO:0019882 96 66 0,000 0,07640087 0,0818835 ! axon guidance GO:0007411 99 66 0,000 0,07640087 0,08184536 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,07640087 0,08180726 ! regulation of immune effector process GO:0002697 101 66 0,000 0,07640087 0,08176919 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,07751453 0,08292252 ! regulation of endopeptidase activity GO:0052548 99 67 0,000 0,07751453 0,08288397 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,07751453 0,08284546 ! acute inflammatory response GO:0002526 92 68 0,000 0,07862692 0,08399531 ! learning or memory GO:0007611 123 68 0,000 0,07862692 0,08395632 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,07862692 0,08391736 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,07862692 0,08387844 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,07862692 0,08383955 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,07862692 0,0838007 ! rhythmic process GO:0048511 105 68 0,000 0,07862692 0,08376188 ! inorganic anion transport GO:0015698 93 68 0,000 0,07862692 0,0837231 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,07973802 0,08486694 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,07973802 0,08482768 ! response to drug GO:0042493 108 69 0,000 0,07973802 0,08478847 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,08084786 0,08592887 ! humoral immune response GO:0006959 86 70 0,000 0,08084786 0,08588918 ! eye development GO:0001654 111 70 0,000 0,08084786 0,08584952 ! amine transport GO:0015837 101 70 0,000 0,08084786 0,08580991 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,08084786 0,08577033 ! regulation of catabolic process GO:0009894 106 70 0,000 0,08084786 0,08573078 ! muscle cell differentiation GO:0042692 104 71 0,000 0,08195641 0,08686624 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,08195641 0,08682623 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,08195641 0,08678626 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,08195641 0,08674632 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,08195641 0,08670642 ! regulation of peptidase activity GO:0052547 106 72 0,000 0,0830637 0,08783747 ! response to hypoxia GO:0001666 132 72 0,000 0,0830637 0,08779711 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,0830637 0,08775678 ! negative regulation of transport GO:0051051 116 73 0,000 0,08416971 0,08888445 ! regulation of blood pressure GO:0008217 107 73 0,000 0,08416971 0,08884366 ! tube morphogenesis GO:0035239 118 73 0,000 0,08416971 0,0888029 ! mitochondrion organization GO:0007005 104 73 0,000 0,08416971 0,08876219 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,08416971 0,08872151 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,08416971 0,08868086 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,08527445 0,08980368 ! response to oxygen levels GO:0070482 137 74 0,000 0,08527445 0,08976258 ! digestion GO:0007586 97 74 0,000 0,08527445 0,08972152 ! protein import into nucleus GO:0006606 118 74 0,000 0,08527445 0,08968049 ! cellular response to hormone stimulus GO:0032870 109 74 0,000 0,08527445 0,0896395 ! positive regulation of lymphocyte activation GO:0051251 108 74 0,000 0,08527445 0,08959855 ! blood coagulation GO:0007596 116 75 0,000 0,08637792 0,09071654 GO:0050817|coagulation, ! negative regulation of growth GO:0045926 123 75 0,000 0,08637792 0,09067513 ! response to nutrient GO:0007584 104 75 0,000 0,08637792 0,09063377 ! nuclear import GO:0051170 121 75 0,000 0,08637792 0,09059244 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,08637792 0,09055115 ! amine biosynthetic process GO:0009309 97 76 0,000 0,08748012 0,09166482 ! tRNA metabolic process GO:0006399 95 76 0,000 0,08748012 0,09162308 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,08748012 0,09158138 ! regulation of protein transport GO:0051223 114 76 0,000 0,08748012 0,09153971 GO:0070201|regulation of establishment of protein localization, ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,08858106 0,09264959 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,08858106 0,09260747 ! regulation of DNA binding GO:0051101 119 77 0,000 0,08858106 0,0925654 ! gland development GO:0048732 148 77 0,000 0,08858106 0,09252336 ! sex differentiation GO:0007548 105 77 0,000 0,08858106 0,09248136 ! protein ubiquitination GO:0016567 125 77 0,000 0,08858106 0,0924394 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,08858106 0,09239748 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,08858106 0,09235559 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,08858106 0,09231375 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,08968073 0,09341743 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,08968073 0,09337514 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,09077914 0,09447603 ! cellular respiration GO:0045333 107 79 0,000 0,09077914 0,0944333 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,09077914 0,09439061 ! T cell activation GO:0042110 134 79 0,000 0,09077914 0,09434796 ! regulation of lyase activity GO:0051339 133 79 0,000 0,09077914 0,09430534 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,09077914 0,09426277 ! chromatin assembly GO:0031497 102 80 0,000 0,09187629 0,09535896 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,09187629 0,09531595 ! protein localization in nucleus GO:0034504 133 80 0,000 0,09187629 0,09527298 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,09187629 0,09523004 ! forebrain development GO:0030900 131 80 0,000 0,09187629 0,09518715 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,09297217 0,09627915 ! hemostasis GO:0007599 125 81 0,000 0,09297217 0,09623582 ! mRNA transport GO:0051028 121 81 0,000 0,09297217 0,09619253 ! regulation of neurological system process GO:0031644 122 81 0,000 0,09297217 0,09614928 ! vitamin metabolic process GO:0006766 103 81 0,000 0,09297217 0,09610607 ! positive regulation of cell activation GO:0050867 120 81 0,000 0,09297217 0,09606289 GO:0002696|positive regulation of leukocyte activation, ! ossification GO:0001503 134 82 0,000 0,0940668 0,09715027 GO:0060348|bone development, ! detection of stimulus GO:0051606 108 82 0,000 0,0940668 0,09710666 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,09516017 0,09819129 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,09516017 0,09814726 ! regulation of cell adhesion GO:0030155 159 83 0,000 0,09516017 0,09810327 ! regulation of defense response GO:0031347 117 84 0,000 0,09625228 0,0991847 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,09625228 0,09914028 ! sterol metabolic process GO:0016125 120 84 0,000 0,09625228 0,0990959 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,09734313 0,10017414 ! rRNA metabolic process GO:0016072 107 85 0,000 0,09734313 0,10012934 GO:0006364|rRNA processing, ! positive regulation of MAP kinase activity GO:0043406 121 85 0,000 0,09734313 0,10008458 ! transcription initiation GO:0006352 118 85 0,000 0,09734313 0,10003986 ! anterior/posterior pattern formation GO:0009952 124 85 0,000 0,09734313 0,09999518 ! regulation of protein localization GO:0032880 132 85 0,000 0,09734313 0,09995054 ! regulation of membrane potential GO:0042391 128 85 0,000 0,09734313 0,09990594 ! negative regulation of multicellular organismal process GO:0051241 133 85 0,000 0,09734313 0,09986138 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,09843274 0,10093415 ! cell cycle arrest GO:0007050 150 86 0,000 0,09843274 0,10088917 ! nucleosome organization GO:0034728 114 87 0,000 0,09952108 0,10195924 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,09952108 0,10191384 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,09952108 0,10186849 ! skeletal muscle tissue development GO:0007519 123 87 0,000 0,09952108 0,10182317 GO:0060538|skeletal muscle organ development, ! female pregnancy GO:0007565 130 87 0,000 0,09952108 0,1017779 ! Wnt receptor signaling pathway GO:0016055 130 87 0,000 0,09952108 0,10173266 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,10060818 0,10279823 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,10060818 0,10275258 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,10060818 0,10270698 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,10060818 0,10266141 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 0,000 0,10060818 0,10261588 ! regulation of neurogenesis GO:0050767 153 89 0,000 0,10169403 0,10367742 ! reproductive developmental process GO:0003006 127 89 0,000 0,10169403 0,10363149 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,10169403 0,10358559 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,10169403 0,10353974 ! regulation of T cell activation GO:0050863 128 89 0,000 0,10169403 0,10349392 ! leukocyte differentiation GO:0002521 143 90 0,000 0,10277863 0,10455146 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,10277863 0,10450524 ! hormone metabolic process GO:0042445 121 90 0,000 0,10277863 0,10445906 ! RNA localization GO:0006403 135 91 0,000 0,10386198 0,10551349 ! ATP metabolic process GO:0046034 137 91 0,000 0,10386198 0,10546691 ! response to virus GO:0009615 122 91 0,000 0,10386198 0,10542037 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,10494408 0,10647172 ! glycerophospholipid metabolic process GO:0006650 130 92 0,000 0,10494408 0,10642478 ! cell fate commitment GO:0045165 141 92 0,000 0,10494408 0,10637787 ! positive regulation of immune response GO:0050778 121 92 0,000 0,10494408 0,10633101 ! DNA recombination GO:0006310 146 92 0,000 0,10494408 0,10628419 ! sulfur metabolic process GO:0006790 118 92 0,000 0,10494408 0,10623741 ! regulation of cytoskeleton organization GO:0051493 154 93 0,000 0,10602495 0,10728437 ! peptidyl-amino acid modification GO:0018193 147 93 0,000 0,10602495 0,10723719 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,10602495 0,10719006 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,10602495 0,10714296 ! electron transport chain GO:0022900 123 94 0,000 0,10710456 0,10818643 ! response to oxidative stress GO:0006979 141 94 0,000 0,10710456 0,10813894 ! regulation of binding GO:0051098 151 95 0,000 0,10818294 0,1091798 ! angiogenesis GO:0001525 149 95 0,000 0,10818294 0,10913191 ! carboxylic acid transport GO:0046942 147 95 0,000 0,10818294 0,10908407 GO:0015849|organic acid transport, ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,10926008 0,1101219 ! in utero embryonic development GO:0001701 147 96 0,000 0,10926008 0,11007366 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,10926008 0,11002547 ! regulation of cellular component biogenesis GO:0044087 158 96 0,000 0,10926008 0,10997732 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,10926008 0,10992921 ! protein maturation GO:0051604 129 96 0,000 0,10926008 0,10988114 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,11033597 0,11091466 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,11033597 0,1108662 ! calcium ion transport GO:0006816 167 99 0,000 0,11248405 0,11297525 ! extracellular structure organization GO:0043062 156 99 0,000 0,11248405 0,11292594 ! protein import GO:0017038 156 99 0,000 0,11248405 0,11287667 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 0,000 0,11248405 0,11282744 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,11355624 0,11385325 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,11355624 0,11380364 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,11355624 0,11375407 ! divalent metal ion transport GO:0070838 171 100 0,000 0,11355624 0,11370455 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,11355624 0,11365507 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,11355624 0,11360563 ! protein localization in organelle GO:0033365 161 100 0,000 0,11355624 0,11355624