pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-b1/out-0.05-06-0.01-300-run-b1//th1-pval-1e-01-08-th2-pval-1e-02-02-th3-pval-1e-01-01-run-b1/go_data/2017-2-real-Zhang-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! NLS-bearing substrate import into nucleus GO:0006607 33 16 2,000 1,429E-06 3,287E-03 ! response to UV GO:0009411 75 46 2,000 3,765E-05 0,04330314 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 4,105E-05 0,03147128 ! regulation of DNA replication GO:0006275 75 48 2,000 4,282E-05 0,02462315 ! double-strand break repair via homologous recombination GO:0000724 16 11 1,000 1,071E-04 0,04928164 GO:0000725|recombinational repair, ! protein import into nucleus GO:0006606 118 74 2,000 1,566E-04 0,06003288 ! nuclear import GO:0051170 121 75 2,000 1,63E-04 0,05355026 ! G1/S transition checkpoint GO:0031575 33 14 1,000 1,768E-04 0,05082779 ! protein localization in nucleus GO:0034504 133 80 2,000 1,974E-04 0,05043881 ! cellular response to unfolded protein GO:0034620 19 16 1,000 2,327E-04 0,05352658 GO:0030968|endoplasmic reticulum unfolded protein response, ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 1,000 2,327E-04 0,04866053 ! regulation of DNA metabolic process GO:0051052 135 85 2,000 2,362E-04 0,04526295 ! response to light stimulus GO:0009416 153 96 2,000 3,381E-04 0,05981671 ! protein import GO:0017038 156 99 2,000 3,701E-04 0,06080227 ! Ras protein signal transduction GO:0007265 162 100 2,000 3,812E-04 0,05844877 ! protein localization in organelle GO:0033365 161 100 2,000 3,812E-04 0,05479572 ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 4,055E-04 0,0548599 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 4,877E-04 0,06231196 ! negative regulation of DNA replication GO:0008156 35 23 1,000 4,877E-04 0,05903238 ! insulin receptor signaling pathway GO:0008286 40 24 1,000 5,315E-04 0,06112543 ! fat cell differentiation GO:0045444 37 24 1,000 5,315E-04 0,05821469 ! base-excision repair GO:0006284 31 24 1,000 5,315E-04 0,05556857 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 1,000 6,248E-04 0,06247946 ! DNA damage checkpoint GO:0000077 53 31 1,000 8,9E-04 0,08529452 ! negative regulation of DNA metabolic process GO:0051053 48 32 1,000 9,485E-04 0,08726512 ! mitotic cell cycle checkpoint GO:0007093 63 34 1,000 1,071E-03 0,09473879 ! DNA integrity checkpoint GO:0031570 57 34 1,000 1,071E-03 0,09122995 ! cellular response to insulin stimulus GO:0032869 52 34 1,000 1,071E-03 0,08797174 ! amino acid activation GO:0043038 52 37 1,000 1,268E-03 0,10057122 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! response to calcium ion GO:0051592 58 40 1,000 1,481E-03 0,11356127 ! double-strand break repair GO:0006302 67 40 1,000 1,481E-03 0,10989801 ! receptor-mediated endocytosis GO:0006898 76 42 1,000 1,632E-03 0,11731399 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 1,000 1,71E-03 0,11920387 ! response to insulin stimulus GO:0032868 63 43 1,000 1,71E-03 0,11569787 ! positive regulation of cell cycle GO:0045787 77 45 1,000 1,872E-03 0,12300523 ! regulation of translational initiation GO:0006446 64 45 1,000 1,872E-03 0,11958842 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 1,000 2,398E-03 0,14906826 ! nucleotide-excision repair GO:0006289 64 52 1,000 2,492E-03 0,15081925 ! DNA damage response, signal transduction GO:0042770 96 56 1,000 2,884E-03 0,17007238 ! response to peptide hormone stimulus GO:0043434 84 57 1,000 2,986E-03 0,17170021 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 1,000 3,412E-03 0,19140202 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 1,000 3,523E-03 0,1929043 ! cell cycle checkpoint GO:0000075 108 64 1,000 3,749E-03 0,20052228 ! neuropeptide signaling pathway GO:0007218 79 64 1,000 3,749E-03 0,19596495 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 1,000 3,749E-03 0,19161018 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 1,000 3,865E-03 0,19322644 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 1,000 3,865E-03 0,18911524 ! positive regulation of ligase activity GO:0051351 99 69 1,000 4,344E-03 0,20812775 ! response to metal ion GO:0010038 103 70 1,000 4,467E-03 0,20969346 ! positive regulation of phosphorylation GO:0042327 102 70 1,000 4,467E-03 0,2054996 ! phosphoinositide-mediated signaling GO:0048015 109 71 1,000 4,593E-03 0,2071289 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 1,000 4,593E-03 0,20314565 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 1,000 4,72E-03 0,20482838 GO:0045937|positive regulation of phosphate metabolic process, ! cellular response to hormone stimulus GO:0032870 109 74 1,000 4,979E-03 0,21206909 ! response to inorganic substance GO:0010035 115 75 1,000 5,111E-03 0,21373104 ! regulation of ligase activity GO:0051340 114 75 1,000 5,111E-03 0,20991441 ! tRNA metabolic process GO:0006399 95 76 1,000 5,245E-03 0,21162067 ! response to unfolded protein GO:0006986 99 76 1,000 5,245E-03 0,20797203 ! positive regulation of protein modification process GO:0031401 107 78 1,000 5,516E-03 0,21504682 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 1,000 5,795E-03 0,22213002 GO:0010498|proteasomal protein catabolic process, ! response to protein stimulus GO:0051789 111 81 1,000 5,936E-03 0,22382444 ! interphase of mitotic cell cycle GO:0051329 156 86 1,000 6,667E-03 0,2473392 ! interphase GO:0051325 159 88 1,000 6,971E-03 0,25449004 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 7,131E-03 0,25625609 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 7,131E-03 0,25231368 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 7,131E-03 0,24849075 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 7,131E-03 0,24478193 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 7,131E-03 0,2411822 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 7,131E-03 0,2376868 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 7,131E-03 0,23429128 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 7,131E-03 0,2309914 ! sleep GO:0030431 11 5 0,000 7,131E-03 0,22778319 ! negative regulation of bone resorption GO:0045779 10 5 0,000 7,131E-03 0,22466287 ! nucleotide-sugar transport GO:0015780 8 5 0,000 7,131E-03 0,22162689 ! regulation of interferon-beta production GO:0032648 5 5 0,000 7,131E-03 0,21867186 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 7,131E-03 0,2157946 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 7,131E-03 0,21299207 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 7,131E-03 0,2102614 ! tongue development GO:0043586 6 5 0,000 7,131E-03 0,20759987 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 7,131E-03 0,20500487 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 7,131E-03 0,20247394 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 7,131E-03 0,20000475 ! cobalt ion transport GO:0006824 9 5 0,000 7,131E-03 0,19759505 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 7,131E-03 0,19524273 ! SMAD protein complex assembly GO:0007183 9 5 0,000 7,131E-03 0,19294576 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 7,131E-03 0,1907022 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 7,131E-03 0,18851022 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 7,131E-03 0,18636806 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 7,131E-03 0,18427404 ! embryonic camera-type eye development GO:0031076 8 5 0,000 7,131E-03 0,18222655 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 7,131E-03 0,18022406 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 7,131E-03 0,1782651 ! adaptation of signaling pathway GO:0022401 7 5 0,000 7,131E-03 0,17634827 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 7,131E-03 0,17447223 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 7,131E-03 0,17263568 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 7,131E-03 0,17083739 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 7,131E-03 0,16907618 ! positive regulation of histone modification GO:0031058 5 5 0,000 7,131E-03 0,16735091 ! malate metabolic process GO:0006108 7 5 0,000 7,131E-03 0,1656605 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 7,131E-03 0,1640039 ! behavioral response to pain GO:0048266 7 5 0,000 7,131E-03 0,16238009 ! clathrin coat assembly GO:0048268 11 5 0,000 7,131E-03 0,16078813 ! phototransduction, visible light GO:0007603 6 5 0,000 7,131E-03 0,15922708 ! regulation of dopamine uptake GO:0051584 9 5 0,000 7,131E-03 0,15769605 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 7,131E-03 0,15619419 ! mating behavior GO:0007617 6 5 0,000 7,131E-03 0,15472066 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 7,131E-03 0,15327467 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 7,131E-03 0,15185546 ! rhythmic behavior GO:0007622 12 5 0,000 7,131E-03 0,15046229 ! copulation GO:0007620 7 5 0,000 7,131E-03 0,14909445 ! glial cell fate commitment GO:0021781 12 5 0,000 7,131E-03 0,14775126 ! protein maturation by protein folding GO:0022417 12 5 0,000 7,131E-03 0,14643205 ! embryonic hemopoiesis GO:0035162 10 5 0,000 7,131E-03 0,14513619 ! regulation of potassium ion transport GO:0043266 9 5 0,000 7,131E-03 0,14386307 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 7,131E-03 0,14261208 ! apoptotic cell clearance GO:0043277 13 5 0,000 7,131E-03 0,14138267 ! lipoprotein particle clearance GO:0034381 9 5 0,000 7,131E-03 0,14017427 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 7,131E-03 0,13898635 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 7,131E-03 0,1378184 ! response to protozoan GO:0001562 9 5 0,000 7,131E-03 0,13666991 ! positive regulation of glycolysis GO:0045821 11 5 0,000 7,131E-03 0,13554041 ! lymph vessel development GO:0001945 7 5 0,000 7,131E-03 0,13442942 ! endochondral ossification GO:0001958 12 5 0,000 7,131E-03 0,1333365 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 7,131E-03 0,13226121 ! parathyroid gland development GO:0060017 8 5 0,000 7,131E-03 0,13120312 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 7,131E-03 0,13016182 ! anagen GO:0042640 6 5 0,000 7,131E-03 0,12913693 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 7,131E-03 0,12812804 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 7,131E-03 0,1271348 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 7,131E-03 0,12615684 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 7,131E-03 0,12519381 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 7,131E-03 0,12424538 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 7,131E-03 0,1233112 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 7,131E-03 0,12239097 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 7,131E-03 0,12148437 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 7,131E-03 0,1205911 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 7,131E-03 0,11971087 ! cardiac muscle fiber development GO:0048739 7 5 0,000 7,131E-03 0,1188434 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 7,131E-03 0,11798841 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 7,131E-03 0,11714564 ! neutrophil mediated immunity GO:0002446 6 5 0,000 7,131E-03 0,11631482 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 7,131E-03 0,1154957 ! ovulation GO:0030728 6 5 0,000 7,131E-03 0,11468804 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 7,131E-03 0,11389159 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 7,131E-03 0,11310613 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 7,131E-03 0,11233144 ! response to pH GO:0009268 9 5 0,000 7,131E-03 0,11156728 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 7,131E-03 0,11081344 ! proline biosynthetic process GO:0006561 6 5 0,000 7,131E-03 0,11006973 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 7,131E-03 0,10933593 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 7,131E-03 0,10861185 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 7,131E-03 0,1078973 ! polyol catabolic process GO:0046174 7 5 0,000 7,131E-03 0,10719209 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 7,131E-03 0,10649604 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 7,131E-03 0,10580896 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 7,131E-03 0,1051307 ! sister chromatid cohesion GO:0007062 9 5 0,000 7,131E-03 0,10446108 ! nerve growth factor processing GO:0032455 7 5 0,000 7,131E-03 0,10379993 ! urea metabolic process GO:0019627 6 5 0,000 7,131E-03 0,1031471 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 7,131E-03 0,10250243 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 7,131E-03 0,10186577 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 7,131E-03 0,10123697 ! neutrophil activation GO:0042119 5 5 0,000 7,131E-03 0,10061589 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 7,131E-03 0,10000238 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 7,131E-03 0,0993963 ! response to food GO:0032094 5 5 0,000 7,131E-03 0,09879753 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 7,131E-03 0,09820593 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 7,131E-03 0,09762137 ! paraxial mesoderm development GO:0048339 9 5 0,000 7,131E-03 0,09704372 ! forebrain neuron development GO:0021884 7 5 0,000 7,131E-03 0,09647288 ! melanosome organization GO:0032438 7 5 0,000 7,131E-03 0,09590871 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 7,131E-03 0,0953511 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 7,131E-03 0,09479994 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 7,131E-03 0,09425511 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 7,131E-03 0,09371651 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 7,131E-03 0,09318403 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 7,131E-03 0,09265757 ! nucleoside transport GO:0015858 6 5 0,000 7,131E-03 0,09213702 ! nucleoside salvage GO:0043174 7 5 0,000 7,131E-03 0,09162229 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 7,131E-03 0,09111328 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 7,131E-03 0,09060989 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 7,131E-03 0,09011203 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 7,131E-03 0,08961961 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 7,131E-03 0,08913255 ! early endosome to late endosome transport GO:0045022 11 5 0,000 7,131E-03 0,08865075 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 7,131E-03 0,08817414 ! depyrimidination GO:0045008 8 5 0,000 7,131E-03 0,08770262 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 7,131E-03 0,08723611 ! 5S class rRNA transcription GO:0042791 8 5 0,000 7,131E-03 0,08677455 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 7,131E-03 0,08631784 ! regulation of centrosome cycle GO:0046605 7 5 0,000 7,131E-03 0,08586591 ! neuronal ion channel clustering GO:0045161 7 5 0,000 7,131E-03 0,0854187 ! sodium ion homeostasis GO:0055078 6 5 0,000 7,131E-03 0,08497611 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 7,131E-03 0,08453809 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 7,131E-03 0,08410456 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 7,131E-03 0,08367546 ! monocyte differentiation GO:0030224 8 5 0,000 7,131E-03 0,08325071 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 7,131E-03 0,08283025 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 7,131E-03 0,08241402 ! centrosome duplication GO:0051298 5 5 0,000 7,131E-03 0,08200195 ! response to UV-C GO:0010225 6 5 0,000 7,131E-03 0,08159398 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 7,131E-03 0,08119005 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 7,131E-03 0,0807901 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 7,131E-03 0,08039407 ! regulation of dendrite development GO:0050773 12 5 0,000 7,131E-03 0,0800019 ! peptidyl-arginine modification GO:0018195 7 5 0,000 7,131E-03 0,07961354 ! positive regulation of organ growth GO:0046622 6 5 0,000 7,131E-03 0,07922893 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 7,131E-03 0,07884803 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 7,131E-03 0,07847076 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 7,131E-03 0,07809709 ! regulation of dopamine secretion GO:0014059 12 5 0,000 7,131E-03 0,07772696 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 7,131E-03 0,07736033 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 7,131E-03 0,07699713 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 7,131E-03 0,07663733 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 7,131E-03 0,07628088 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 7,131E-03 0,07592773 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 7,131E-03 0,07557783 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 7,131E-03 0,07523114 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 7,131E-03 0,07488762 ! neural tube patterning GO:0021532 6 5 0,000 7,131E-03 0,07454723 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 7,131E-03 0,07420991 ! histone demethylation GO:0016577 9 5 0,000 7,131E-03 0,07387563 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 7,131E-03 0,07354435 ! regulation of sterol transport GO:0032371 7 5 0,000 7,131E-03 0,07321602 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 7,131E-03 0,07289062 ! enteric nervous system development GO:0048484 8 5 0,000 7,131E-03 0,0725681 ! establishment of planar polarity GO:0001736 6 5 0,000 7,131E-03 0,07224841 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 7,131E-03 0,07193153 ! muscle cell proliferation GO:0033002 8 5 0,000 7,131E-03 0,07161742 ! transcription termination GO:0006353 8 5 0,000 7,131E-03 0,07130604 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 7,131E-03 0,07099736 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 7,131E-03 0,07069133 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 7,131E-03 0,07038794 ! regulation of respiratory burst GO:0060263 8 5 0,000 7,131E-03 0,07008713 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 7,131E-03 0,06978889 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 7,131E-03 0,06949318 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 7,131E-03 0,06919996 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 7,131E-03 0,0689092 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 7,131E-03 0,06862088 ! apical protein localization GO:0045176 6 5 0,000 7,131E-03 0,06833496 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 7,131E-03 0,06805141 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 7,131E-03 0,0677702 ! galactolipid metabolic process GO:0019374 7 5 0,000 7,131E-03 0,06749131 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 7,131E-03 0,06721471 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 7,131E-03 0,06694037 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 7,131E-03 0,06666825 ! triglyceride catabolic process GO:0019433 6 5 0,000 7,131E-03 0,06639834 ! glial cell migration GO:0008347 10 5 0,000 7,131E-03 0,0661306 ! determination of adult lifespan GO:0008340 8 5 0,000 7,131E-03 0,06586502 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 7,131E-03 0,06560156 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 7,131E-03 0,0653402 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 7,131E-03 0,06508091 ! somatic stem cell maintenance GO:0035019 13 5 0,000 7,131E-03 0,06482367 ! cerebellar cortex formation GO:0021697 6 5 0,000 7,131E-03 0,06456846 ! neural plate development GO:0001840 6 5 0,000 7,131E-03 0,06431525 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 7,131E-03 0,06406402 ! regulation of sensory perception GO:0051931 6 5 0,000 7,131E-03 0,06381475 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 7,131E-03 0,0635674 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 7,131E-03 0,06332197 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 7,131E-03 0,06307842 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 7,131E-03 0,06283674 ! sensory cilium assembly GO:0035058 6 5 0,000 7,131E-03 0,06259691 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 7,131E-03 0,0623589 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 7,131E-03 0,06212269 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 7,131E-03 0,06188826 ! spindle assembly GO:0051225 5 5 0,000 7,131E-03 0,0616556 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 7,131E-03 0,06142468 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 7,131E-03 0,06119548 ! protein amino acid prenylation GO:0018346 9 5 0,000 7,131E-03 0,06096799 ! organ regeneration GO:0031100 7 5 0,000 7,131E-03 0,06074218 ! NAD biosynthetic process GO:0009435 7 5 0,000 7,131E-03 0,06051804 ! carnitine metabolic process GO:0009437 5 5 0,000 7,131E-03 0,06029555 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 7,131E-03 0,06007469 ! cellular anion homeostasis GO:0030002 6 5 0,000 7,131E-03 0,05985544 GO:0055081|anion homeostasis, ! DNA recombination GO:0006310 146 92 1,000 7,596E-03 0,06353171 ! tRNA transcription GO:0009304 11 6 0,000 8,551E-03 0,07125713 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 8,551E-03 0,07099988 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 8,551E-03 0,07074449 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 8,551E-03 0,07049092 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 8,551E-03 0,07023917 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 8,551E-03 0,06998921 ! regulation of helicase activity GO:0051095 11 6 0,000 8,551E-03 0,06974102 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 8,551E-03 0,06949459 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 8,551E-03 0,06924989 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 8,551E-03 0,0690069 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 8,551E-03 0,06876562 ! positive regulation of axon extension GO:0045773 8 6 0,000 8,551E-03 0,06852602 ! prostate gland development GO:0030850 9 6 0,000 8,551E-03 0,06828808 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 8,551E-03 0,06805179 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 8,551E-03 0,06781713 ! forebrain neuron differentiation GO:0021879 9 6 0,000 8,551E-03 0,06758408 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 8,551E-03 0,06735263 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 8,551E-03 0,06712276 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 8,551E-03 0,06689445 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 8,551E-03 0,06666769 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 8,551E-03 0,06644246 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 8,551E-03 0,06621875 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 8,551E-03 0,06599654 ! neuron adhesion GO:0007158 9 6 0,000 8,551E-03 0,06577581 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 8,551E-03 0,06555656 ! establishment of tissue polarity GO:0007164 7 6 0,000 8,551E-03 0,06533876 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 8,551E-03 0,06512241 ! signal peptide processing GO:0006465 8 6 0,000 8,551E-03 0,06490748 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 8,551E-03 0,06469397 ! mRNA stabilization GO:0048255 15 6 0,000 8,551E-03 0,06448186 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 8,551E-03 0,06427114 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 8,551E-03 0,06406178 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 8,551E-03 0,06385379 ! opsonization GO:0008228 8 6 0,000 8,551E-03 0,06364715 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 8,551E-03 0,06344183 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 8,551E-03 0,06323784 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 8,551E-03 0,06303515 ! protein amino acid dealkylation GO:0008214 11 6 0,000 8,551E-03 0,06283376 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 8,551E-03 0,06263366 ! photoreceptor cell development GO:0042461 10 6 0,000 8,551E-03 0,06243482 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 8,551E-03 0,06223724 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 8,551E-03 0,06204091 ! mechanosensory behavior GO:0007638 8 6 0,000 8,551E-03 0,06184581 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 8,551E-03 0,06165194 ! negative regulation of endocytosis GO:0045806 8 6 0,000 8,551E-03 0,06145927 ! response to interferon-gamma GO:0034341 12 6 0,000 8,551E-03 0,06126781 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 8,551E-03 0,06107754 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 8,551E-03 0,06088845 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 8,551E-03 0,06070052 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 8,551E-03 0,06051375 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 8,551E-03 0,06032812 ! cGMP-mediated signaling GO:0019934 10 6 0,000 8,551E-03 0,06014363 ! activation of MAPKKK activity GO:0000185 10 6 0,000 8,551E-03 0,05996027 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 8,551E-03 0,05977802 ! thymic T cell selection GO:0045061 12 6 0,000 8,551E-03 0,05959687 ! protein lipoylation GO:0009249 10 6 0,000 8,551E-03 0,05941682 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 8,551E-03 0,05923786 ! pigment granule organization GO:0048753 11 6 0,000 8,551E-03 0,05905996 ! drug transport GO:0015893 6 6 0,000 8,551E-03 0,05888314 ! cysteine metabolic process GO:0006534 7 6 0,000 8,551E-03 0,05870737 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 8,551E-03 0,05853264 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 8,551E-03 0,05835896 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 8,551E-03 0,0581863 ! histidine metabolic process GO:0006547 6 6 0,000 8,551E-03 0,05801465 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 8,551E-03 0,05784402 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 8,551E-03 0,05767439 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 8,551E-03 0,05750575 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 8,551E-03 0,0573381 ! adenohypophysis development GO:0021984 10 6 0,000 8,551E-03 0,05717142 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 8,551E-03 0,0570057 ! hyperosmotic response GO:0006972 8 6 0,000 8,551E-03 0,05684095 ! microtubule nucleation GO:0007020 10 6 0,000 8,551E-03 0,05667714 ! ER overload response GO:0006983 7 6 0,000 8,551E-03 0,05651428 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 8,551E-03 0,05635234 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 8,551E-03 0,05619134 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 8,551E-03 0,05603125 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 8,551E-03 0,05587207 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 8,551E-03 0,05571379 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 8,551E-03 0,05555641 ! response to dietary excess GO:0002021 7 6 0,000 8,551E-03 0,05539991 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 8,551E-03 0,05524429 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 8,551E-03 0,05508955 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 8,551E-03 0,05493566 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 8,551E-03 0,05478264 ! glycerol ether catabolic process GO:0044269 8 6 0,000 8,551E-03 0,05463047 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 8,551E-03 0,05447914 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 8,551E-03 0,05432864 ! neuron apoptosis GO:0051402 8 6 0,000 8,551E-03 0,05417897 ! organic alcohol transport GO:0015850 9 6 0,000 8,551E-03 0,05403013 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 8,551E-03 0,0538821 ! T cell mediated immunity GO:0002456 12 6 0,000 8,551E-03 0,05373488 ! male sex determination GO:0030238 9 6 0,000 8,551E-03 0,05358847 ! carnitine transport GO:0015879 8 6 0,000 8,551E-03 0,05344285 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 8,551E-03 0,05329802 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 8,551E-03 0,05315397 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 8,551E-03 0,0530107 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 8,551E-03 0,05286819 ! positive regulation of exocytosis GO:0045921 6 6 0,000 8,551E-03 0,05272646 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 8,551E-03 0,05258548 ! parturition GO:0007567 12 6 0,000 8,551E-03 0,05244525 ! negative regulation of translational initiation GO:0045947 7 6 0,000 8,551E-03 0,05230577 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 8,551E-03 0,05216702 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 8,551E-03 0,05202902 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 8,551E-03 0,05189174 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 8,551E-03 0,05175518 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 8,551E-03 0,05161934 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 8,551E-03 0,05148421 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 8,551E-03 0,05134979 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 8,551E-03 0,05121606 ! macrophage differentiation GO:0030225 10 6 0,000 8,551E-03 0,05108303 ! astrocyte development GO:0014002 14 6 0,000 8,551E-03 0,05095069 ! hyaluronan metabolic process GO:0030212 6 6 0,000 8,551E-03 0,05081904 ! purine base biosynthetic process GO:0009113 14 6 0,000 8,551E-03 0,05068806 ! interaction with symbiont GO:0051702 8 6 0,000 8,551E-03 0,05055776 ! anterograde axon cargo transport GO:0008089 8 6 0,000 8,551E-03 0,05042812 ! skeletal muscle contraction GO:0003009 6 6 0,000 8,551E-03 0,05029915 ! eating behavior GO:0042755 6 6 0,000 8,551E-03 0,05017084 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 8,551E-03 0,05004318 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 8,551E-03 0,04991616 ! response to copper ion GO:0046688 9 6 0,000 8,551E-03 0,04978979 ! DNA topological change GO:0006265 8 6 0,000 8,551E-03 0,04966406 ! response to exogenous dsRNA GO:0043330 8 6 0,000 8,551E-03 0,04953896 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 8,551E-03 0,04941449 ! establishment of melanosome localization GO:0032401 9 6 0,000 8,551E-03 0,04929065 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 8,551E-03 0,04916742 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 8,551E-03 0,04904481 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 8,551E-03 0,04892281 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 8,551E-03 0,04880141 ! nucleoside catabolic process GO:0009164 6 6 0,000 8,551E-03 0,04868061 ! gas homeostasis GO:0033483 11 6 0,000 8,551E-03 0,04856041 ! hair follicle maturation GO:0048820 7 6 0,000 8,551E-03 0,04844081 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 8,551E-03 0,04832179 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 8,551E-03 0,04820335 ! Schwann cell development GO:0014044 14 6 0,000 8,551E-03 0,0480855 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 8,551E-03 0,04796821 ! dendrite morphogenesis GO:0048813 9 6 0,000 8,551E-03 0,0478515 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 8,551E-03 0,04773536 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 8,551E-03 0,04761978 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 8,551E-03 0,04750475 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 8,551E-03 0,04739028 ! histone ubiquitination GO:0016574 7 6 0,000 8,551E-03 0,04727637 ! regulation of meiosis GO:0040020 10 6 0,000 8,551E-03 0,04716299 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 8,551E-03 0,04705016 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 8,551E-03 0,04693787 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 8,551E-03 0,04682611 ! regulation of mast cell activation GO:0033003 6 6 0,000 8,551E-03 0,04671489 ! membrane to membrane docking GO:0022614 12 6 0,000 8,551E-03 0,04660419 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 8,551E-03 0,04649401 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 8,551E-03 0,04638436 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 8,551E-03 0,04627522 ! receptor internalization GO:0031623 9 6 0,000 8,551E-03 0,04616659 ! neutrophil homeostasis GO:0001780 6 6 0,000 8,551E-03 0,04605847 ! coenzyme A metabolic process GO:0015936 9 6 0,000 8,551E-03 0,04595086 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 8,551E-03 0,04584375 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 8,551E-03 0,04573713 ! protein deubiquitination GO:0016579 8 6 0,000 8,551E-03 0,04563102 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 8,551E-03 0,04552539 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 8,551E-03 0,04542025 ! peptidyl-histidine modification GO:0018202 9 6 0,000 8,551E-03 0,04531559 ! axonal fasciculation GO:0007413 9 6 0,000 8,551E-03 0,04521142 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 8,551E-03 0,04510772 ! thiamin metabolic process GO:0006772 6 6 0,000 8,551E-03 0,0450045 ! midbrain development GO:0030901 6 6 0,000 8,551E-03 0,04490175 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 8,551E-03 0,04479947 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 8,551E-03 0,04469765 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 8,551E-03 0,0445963 ! progesterone metabolic process GO:0042448 8 6 0,000 8,551E-03 0,0444954 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 8,551E-03 0,04439496 ! glycolipid catabolic process GO:0019377 13 6 0,000 8,551E-03 0,04429497 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 8,551E-03 0,04419543 ! positive regulation of glucose import GO:0046326 6 6 0,000 8,551E-03 0,04409634 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 8,551E-03 0,04399769 ! adult feeding behavior GO:0008343 6 6 0,000 8,551E-03 0,04389948 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 8,551E-03 0,04380171 ! blastocyst growth GO:0001832 15 6 0,000 8,551E-03 0,04370437 ! pigment granule transport GO:0051904 12 6 0,000 8,551E-03 0,04360747 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 8,551E-03 0,04351099 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 8,551E-03 0,04341494 ! catecholamine transport GO:0051937 7 6 0,000 8,551E-03 0,04331931 ! organ or tissue specific immune response GO:0002251 7 6 0,000 8,551E-03 0,04322411 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 8,551E-03 0,04312932 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 8,551E-03 0,04303494 ! negative regulation of B cell activation GO:0050869 9 6 0,000 8,551E-03 0,04294098 ! protein prenylation GO:0018342 10 6 0,000 8,551E-03 0,04284742 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 8,551E-03 0,04275428 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 8,551E-03 0,04266154 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 8,551E-03 0,04256919 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 8,551E-03 0,04247725 ! positive regulation of coagulation GO:0050820 11 6 0,000 8,551E-03 0,04238571 ! regulation of translation GO:0006417 151 100 1,000 8,92E-03 0,04412115 ! homophilic cell adhesion GO:0007156 149 100 1,000 8,92E-03 0,04402647 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 9,969E-03 0,04909863 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 9,969E-03 0,04899372 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 9,969E-03 0,04888925 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 9,969E-03 0,04878523 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 9,969E-03 0,04868166 ! synaptonemal complex assembly GO:0007130 10 7 0,000 9,969E-03 0,04857852 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 9,969E-03 0,04847581 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 9,969E-03 0,04837354 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 9,969E-03 0,04827171 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 9,969E-03 0,04817029 ! reproductive behavior GO:0019098 12 7 0,000 9,969E-03 0,04806931 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 9,969E-03 0,04796875 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 9,969E-03 0,0478686 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 9,969E-03 0,04776888 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 9,969E-03 0,04766956 ! oligopeptide transport GO:0006857 11 7 0,000 9,969E-03 0,04757066 ! protein amino acid sulfation GO:0006477 9 7 0,000 9,969E-03 0,04747217 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 9,969E-03 0,04737409 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 9,969E-03 0,04727641 ! RNA methylation GO:0001510 11 7 0,000 9,969E-03 0,04717914 ! pericardium development GO:0060039 8 7 0,000 9,969E-03 0,04708226 ! macrophage chemotaxis GO:0048246 10 7 0,000 9,969E-03 0,04698578 ! fibril organization GO:0043206 13 7 0,000 9,969E-03 0,04688969 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 9,969E-03 0,046794 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 9,969E-03 0,0466987 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 9,969E-03 0,04660378 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 9,969E-03 0,04650925 ! lipoprotein transport GO:0042953 9 7 0,000 9,969E-03 0,0464151 ! cerebral cortex cell migration GO:0021795 11 7 0,000 9,969E-03 0,04632133 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 9,969E-03 0,04622794 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 9,969E-03 0,04613493 ! estrogen metabolic process GO:0008210 14 7 0,000 9,969E-03 0,04604229 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 9,969E-03 0,04595002 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 9,969E-03 0,04585812 ! chemosensory behavior GO:0007635 9 7 0,000 9,969E-03 0,04576659 ! microtubule bundle formation GO:0001578 8 7 0,000 9,969E-03 0,04567542 ! T-helper 1 type immune response GO:0042088 11 7 0,000 9,969E-03 0,04558461 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 9,969E-03 0,04549417 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 9,969E-03 0,04540408 ! leukocyte degranulation GO:0043299 10 7 0,000 9,969E-03 0,04531435 ! bile acid and bile salt transport GO:0015721 9 7 0,000 9,969E-03 0,04522497 ! reflex GO:0060004 12 7 0,000 9,969E-03 0,04513595 ! positive regulation of isotype switching GO:0045830 15 7 0,000 9,969E-03 0,04504727 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 9,969E-03 0,04495894 ! protein-cofactor linkage GO:0018065 13 7 0,000 9,969E-03 0,04487096 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 9,969E-03 0,04478332 ! glycerolipid catabolic process GO:0046503 9 7 0,000 9,969E-03 0,04469602 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 9,969E-03 0,04460907 ! spinal cord patterning GO:0021511 7 7 0,000 9,969E-03 0,04452245 ! hemoglobin metabolic process GO:0020027 10 7 0,000 9,969E-03 0,04443616 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 9,969E-03 0,04435021 ! adrenal gland development GO:0030325 17 7 0,000 9,969E-03 0,0442646 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 9,969E-03 0,04417931 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 9,969E-03 0,04409435 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 9,969E-03 0,04400971 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 9,969E-03 0,0439254 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 9,969E-03 0,04384142 ! endosome organization GO:0007032 10 7 0,000 9,969E-03 0,04375775 ! thyroid hormone generation GO:0006590 11 7 0,000 9,969E-03 0,0436744 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 9,969E-03 0,04359137 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 9,969E-03 0,04350865 ! regulation of pigmentation during development GO:0048070 15 7 0,000 9,969E-03 0,04342625 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 9,969E-03 0,04334416 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 9,969E-03 0,04326238 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 9,969E-03 0,0431809 ! galactose metabolic process GO:0006012 10 7 0,000 9,969E-03 0,04309974 ! vesicle fusion GO:0006906 15 7 0,000 9,969E-03 0,04301887 ! intracellular pH reduction GO:0051452 10 7 0,000 9,969E-03 0,04293832 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 9,969E-03 0,04285806 ! organ growth GO:0035265 11 7 0,000 9,969E-03 0,0427781 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 9,969E-03 0,04269844 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 9,969E-03 0,04261907 ! Rac protein signal transduction GO:0016601 7 7 0,000 9,969E-03 0,04254 ! retinol metabolic process GO:0042572 9 7 0,000 9,969E-03 0,04246122 ! behavioral fear response GO:0001662 13 7 0,000 9,969E-03 0,04238274 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 9,969E-03 0,04230454 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 9,969E-03 0,04222663 ! rRNA modification GO:0000154 12 7 0,000 9,969E-03 0,04214901 ! protein heterooligomerization GO:0051291 10 7 0,000 9,969E-03 0,04207167 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 9,969E-03 0,04199462 ! response to UV-B GO:0010224 11 7 0,000 9,969E-03 0,04191784 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 9,969E-03 0,04184135 ! protein retention in ER lumen GO:0006621 12 7 0,000 9,969E-03 0,04176514 ! intermediate filament organization GO:0045109 11 7 0,000 9,969E-03 0,0416892 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 9,969E-03 0,04161354 ! cardiac muscle cell development GO:0055013 9 7 0,000 9,969E-03 0,04153815 ! fibrinolysis GO:0042730 9 7 0,000 9,969E-03 0,04146304 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 9,969E-03 0,0413882 ! regulation of circadian rhythm GO:0042752 11 7 0,000 9,969E-03 0,04131362 ! B cell lineage commitment GO:0002326 17 7 0,000 9,969E-03 0,04123932 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 9,969E-03 0,04116528 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 9,969E-03 0,04109151 ! response to tropane GO:0014073 13 7 0,000 9,969E-03 0,041018 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 9,969E-03 0,04094475 ! melanosome localization GO:0032400 10 7 0,000 9,969E-03 0,04087177 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 9,969E-03 0,04079904 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 9,969E-03 0,04072657 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 9,969E-03 0,04065436 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 9,969E-03 0,04058241 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 9,969E-03 0,04051071 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 9,969E-03 0,04043926 ! mast cell activation GO:0045576 9 7 0,000 9,969E-03 0,04036806 ! multicellular organismal aging GO:0010259 11 7 0,000 9,969E-03 0,04029712 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 9,969E-03 0,04022642 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 9,969E-03 0,04015597 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 9,969E-03 0,04008577 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 9,969E-03 0,04001581 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 9,969E-03 0,0399461 ! establishment of nucleus localization GO:0040023 13 7 0,000 9,969E-03 0,03987663 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 9,969E-03 0,0398074 ! T cell lineage commitment GO:0002360 12 7 0,000 9,969E-03 0,03973841 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 9,969E-03 0,03966965 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 9,969E-03 0,03960114 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 9,969E-03 0,03953286 ! regulation of lipid transport GO:0032368 13 7 0,000 9,969E-03 0,03946482 ! response to tumor cell GO:0002347 12 7 0,000 9,969E-03 0,03939701 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 9,969E-03 0,03932943 ! neuroblast proliferation GO:0007405 13 7 0,000 9,969E-03 0,03926209 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 9,969E-03 0,03919497 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 9,969E-03 0,03912809 ! peptidyl-threonine modification GO:0018210 18 7 0,000 9,969E-03 0,03906143 ! diuresis GO:0030146 12 7 0,000 9,969E-03 0,038995 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 9,969E-03 0,03892879 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 9,969E-03 0,03886281 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 9,969E-03 0,03879706 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 9,969E-03 0,03873152 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 9,969E-03 0,03866621 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 9,969E-03 0,03860111 ! melanin biosynthetic process GO:0042438 8 7 0,000 9,969E-03 0,03853624 ! regulation of synaptogenesis GO:0051963 10 7 0,000 9,969E-03 0,03847158 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 9,969E-03 0,03840714 ! dopamine biosynthetic process GO:0042416 15 7 0,000 9,969E-03 0,03834291 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 9,969E-03 0,0382789 ! lymph node development GO:0048535 9 7 0,000 9,969E-03 0,0382151 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 9,969E-03 0,03815151 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 9,969E-03 0,03808814 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 9,969E-03 0,03802498 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 9,969E-03 0,03796202 ! endosome to lysosome transport GO:0008333 10 7 0,000 9,969E-03 0,03789927 ! ATP catabolic process GO:0006200 10 7 0,000 9,969E-03 0,03783673 ! establishment of pigment granule localization GO:0051905 13 7 0,000 9,969E-03 0,0377744 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 9,969E-03 0,03771227 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 9,969E-03 0,03765035 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 9,969E-03 0,03758862 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 9,969E-03 0,0375271 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 9,969E-03 0,03746578 ! muscle adaptation GO:0043500 12 7 0,000 9,969E-03 0,03740467 ! amino sugar catabolic process GO:0046348 9 7 0,000 9,969E-03 0,03734375 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 9,969E-03 0,03728302 ! retina homeostasis GO:0001895 9 7 0,000 9,969E-03 0,0372225 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 9,969E-03 0,03716217 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 9,969E-03 0,03710204 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 9,969E-03 0,0370421 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 9,969E-03 0,03698236 ! behavioral response to nicotine GO:0035095 11 7 0,000 9,969E-03 0,0369228 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 9,969E-03 0,03686344 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 9,969E-03 0,03680427 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,01138551 0,04196582 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,01138551 0,04189868 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 0,01138551 0,04183175 ! axon extension GO:0048675 11 8 0,000 0,01138551 0,04176503 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,01138551 0,04169852 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,01138551 0,04163223 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,01138551 0,04156615 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,01138551 0,04150027 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,01138551 0,04143461 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,01138551 0,04136915 ! positive regulation of B cell proliferation GO:0030890 11 8 0,000 0,01138551 0,0413039 ! phosphate transport GO:0006817 10 8 0,000 0,01138551 0,04123885 ! N-glycan processing GO:0006491 12 8 0,000 0,01138551 0,04117401 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,01138551 0,04110938 ! UTP metabolic process GO:0046051 8 8 0,000 0,01138551 0,04104494 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,01138551 0,04098071 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,01138551 0,04091668 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,01138551 0,04085284 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,01138551 0,04078921 ! succinate metabolic process GO:0006105 14 8 0,000 0,01138551 0,04072577 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,01138551 0,04066253 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,01138551 0,04059949 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01138551 0,04053664 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,01138551 0,04047399 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,01138551 0,04041153 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,01138551 0,04034926 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,01138551 0,04028719 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,01138551 0,0402253 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01138551 0,04016361 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,01138551 0,0401021 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,01138551 0,04004078 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,01138551 0,03997965 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,01138551 0,03991871 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,01138551 0,03985795 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,01138551 0,03979737 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,01138551 0,03973698 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,01138551 0,03967678 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 0,000 0,01138551 0,03961675 ! astrocyte differentiation GO:0048708 16 8 0,000 0,01138551 0,03955691 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,01138551 0,03949724 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,01138551 0,03943776 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,01138551 0,03937845 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,01138551 0,03931933 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,01138551 0,03926038 ! melanin metabolic process GO:0006582 12 8 0,000 0,01138551 0,03920161 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,01138551 0,03914301 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01138551 0,03908459 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,01138551 0,03902634 ! macrophage activation GO:0042116 12 8 0,000 0,01138551 0,03896826 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,01138551 0,03891036 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,01138551 0,03885263 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,01138551 0,03879507 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,01138551 0,03873768 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01138551 0,03868046 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,01138551 0,03862341 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,01138551 0,03856653 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,01138551 0,03850981 ! ruffle organization GO:0031529 11 8 0,000 0,01138551 0,03845326 ! osteoblast development GO:0002076 13 8 0,000 0,01138551 0,03839688 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,01138551 0,03834066 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,01138551 0,03828461 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,01138551 0,03822872 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,01138551 0,03817299 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,01138551 0,03811743 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,01138551 0,03806202 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,01138551 0,03800678 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,01138551 0,0379517 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,01138551 0,03789678 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,01138551 0,03784201 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,01138551 0,03778741 ! oligodendrocyte development GO:0014003 8 8 0,000 0,01138551 0,03773296 ! segment specification GO:0007379 10 8 0,000 0,01138551 0,03767867 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,01138551 0,03762453 ! cellular extravasation GO:0045123 11 8 0,000 0,01138551 0,03757055 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,01138551 0,03751672 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,01138551 0,03746305 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,01138551 0,03740953 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,01138551 0,03735617 ! snRNA metabolic process GO:0016073 10 8 0,000 0,01138551 0,03730295 GO:0016180|snRNA processing, ! phosphoinositide 3-kinase cascade GO:0014065 23 8 0,000 0,01138551 0,03724989 ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,01138551 0,03719698 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,01138551 0,03714422 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,01138551 0,0370916 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,01138551 0,03703914 ! nucleosome disassembly GO:0006337 12 8 0,000 0,01138551 0,03698683 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,01138551 0,03693466 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,01138551 0,03688264 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,01138551 0,03683076 ! icosanoid secretion GO:0032309 12 8 0,000 0,01138551 0,03677903 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,01138551 0,03672745 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01138551 0,03667601 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,01138551 0,03662472 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,01138551 0,03657356 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,01138551 0,03652256 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,01138551 0,03647169 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,01138551 0,03642096 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,01138551 0,03637038 ! sterol catabolic process GO:0016127 9 8 0,000 0,01138551 0,03631993 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,01138551 0,03626963 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,01138551 0,03621946 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,01138551 0,03616944 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,01138551 0,03611955 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01138551 0,0360698 ! prophase GO:0051324 11 8 0,000 0,01138551 0,03602018 ! S phase GO:0051320 8 8 0,000 0,01138551 0,0359707 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,01138551 0,03592136 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,01138551 0,03587215 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,01138551 0,03582308 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,01138551 0,03577414 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,01138551 0,03572534 ! hormone catabolic process GO:0042447 13 8 0,000 0,01138551 0,03567667 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,01138551 0,03562813 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,01138551 0,03557972 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,01138551 0,03553144 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,01138551 0,0354833 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,01138551 0,03543528 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,01138551 0,0353874 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,01138551 0,03533964 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01138551 0,03529201 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,01138551 0,03524451 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,01138551 0,03519714 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,01138551 0,0351499 ! lamellipodium assembly GO:0030032 9 8 0,000 0,01138551 0,03510278 ! regulation of embryonic development GO:0045995 16 8 0,000 0,01138551 0,03505579 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01138551 0,03500892 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,01138551 0,03496218 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,01138551 0,03491556 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,01279992 0,03920081 ! regulation of developmental growth GO:0048638 13 9 0,000 0,01279992 0,03914868 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,01279992 0,03909669 ! telencephalon cell migration GO:0022029 16 9 0,000 0,01279992 0,03904484 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,01279992 0,03899313 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,01279992 0,03894155 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,01279992 0,03889011 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,01279992 0,0388388 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,01279992 0,03878763 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,01279992 0,03873659 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,01279992 0,03868569 ! GTP metabolic process GO:0046039 9 9 0,000 0,01279992 0,03863492 ! elastic fiber assembly GO:0048251 13 9 0,000 0,01279992 0,03858429 ! social behavior GO:0035176 14 9 0,000 0,01279992 0,03853378 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,01279992 0,03848341 ! artery development GO:0060840 19 9 0,000 0,01279992 0,03843317 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,01279992 0,03838306 ! regulation of glycolysis GO:0006110 15 9 0,000 0,01279992 0,03833309 ! response to pain GO:0048265 16 9 0,000 0,01279992 0,03828324 ! protein complex disassembly GO:0043241 17 9 0,000 0,01279992 0,03823352 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,01279992 0,03818393 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,01279992 0,03813447 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,01279992 0,03808514 ! lung alveolus development GO:0048286 17 9 0,000 0,01279992 0,03803593 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,01279992 0,03798685 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,01279992 0,0379379 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,01279992 0,03788907 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,01279992 0,03784037 ! ventral spinal cord development GO:0021517 11 9 0,000 0,01279992 0,0377918 ! protein targeting to ER GO:0045047 19 9 0,000 0,01279992 0,03774335 ! T cell selection GO:0045058 18 9 0,000 0,01279992 0,03769502 ! endoderm development GO:0007492 12 9 0,000 0,01279992 0,03764682 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,01279992 0,03759874 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,01279992 0,03755078 ! arginine catabolic process GO:0006527 10 9 0,000 0,01279992 0,03750294 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,01279992 0,03745523 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,01279992 0,03740764 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,01279992 0,03736017 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01279992 0,03731281 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,01279992 0,03726558 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,01279992 0,03721847 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,01279992 0,03717148 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,01279992 0,0371246 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01279992 0,03707785 ! mannose metabolic process GO:0006013 9 9 0,000 0,01279992 0,03703121 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,01279992 0,03698469 ! receptor clustering GO:0043113 15 9 0,000 0,01279992 0,03693828 ! epithelial cell development GO:0002064 10 9 0,000 0,01279992 0,03689199 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,01279992 0,03684582 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,01279992 0,03679976 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,01279992 0,03675382 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,01279992 0,03670799 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,01279992 0,03666228 ! motor axon guidance GO:0008045 14 9 0,000 0,01279992 0,03661668 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,01279992 0,03657119 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,01279992 0,03652582 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,01279992 0,03648056 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,01279992 0,03643541 ! blastoderm segmentation GO:0007350 11 9 0,000 0,01279992 0,03639037 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,01279992 0,03634544 ! DNA ligation GO:0006266 14 9 0,000 0,01279992 0,03630063 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,01279992 0,03625592 ! response to amine stimulus GO:0014075 13 9 0,000 0,01279992 0,03621133 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,01279992 0,03616684 ! erythrocyte development GO:0048821 11 9 0,000 0,01279992 0,03612247 ! renal water homeostasis GO:0003091 14 9 0,000 0,01279992 0,0360782 ! postreplication repair GO:0006301 11 9 0,000 0,01279992 0,03603404 ! mRNA cleavage GO:0006379 13 9 0,000 0,01279992 0,03598999 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,01279992 0,03594604 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,01279992 0,03590221 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,01279992 0,03585848 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,01279992 0,03581485 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,01279992 0,03577134 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,01279992 0,03572793 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,01279992 0,03568462 ! acid secretion GO:0046717 14 9 0,000 0,01279992 0,03564142 ! musculoskeletal movement GO:0050881 11 9 0,000 0,01279992 0,03559832 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,01279992 0,03555533 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,01279992 0,03551244 ! purine base metabolic process GO:0006144 18 9 0,000 0,01279992 0,03546965 ! oocyte differentiation GO:0009994 12 9 0,000 0,01279992 0,03542697 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,01279992 0,03538439 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,01279992 0,03534191 ! spleen development GO:0048536 15 9 0,000 0,01279992 0,03529953 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,01279992 0,03525726 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,01279992 0,03521508 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,01279992 0,03517301 ! detection of calcium ion GO:0005513 13 9 0,000 0,01279992 0,03513104 ! blastocyst formation GO:0001825 12 9 0,000 0,01279992 0,03508917 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,01279992 0,03504739 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,01279992 0,03500572 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,01279992 0,03496415 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,01279992 0,03492267 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01279992 0,03488129 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,01279992 0,03484001 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,01279992 0,03479883 ! prepulse inhibition GO:0060134 14 9 0,000 0,01279992 0,03475775 ! embryonic placenta development GO:0001892 12 9 0,000 0,01279992 0,03471676 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,01279992 0,03467587 ! insulin secretion GO:0030073 17 9 0,000 0,01279992 0,03463507 ! sequestering of metal ion GO:0051238 11 9 0,000 0,01279992 0,03459437 ! response to nicotine GO:0035094 16 9 0,000 0,01279992 0,03455377 ! establishment of cell polarity GO:0030010 12 9 0,000 0,01279992 0,03451326 ! nucleus localization GO:0051647 15 9 0,000 0,01279992 0,03447285 ! regulation of synapse organization GO:0050807 12 9 0,000 0,01279992 0,03443253 ! localization within membrane GO:0051668 15 9 0,000 0,01279992 0,0343923 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,01421238 0,03814292 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,01421238 0,03809846 ! neuron fate specification GO:0048665 11 10 0,000 0,01421238 0,03805411 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,01421238 0,03800986 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,01421238 0,03796571 ! thyroid gland development GO:0030878 19 10 0,000 0,01421238 0,03792167 ! regulation of B cell proliferation GO:0030888 15 10 0,000 0,01421238 0,03787773 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,01421238 0,03783389 ! synapsis GO:0007129 13 10 0,000 0,01421238 0,03779015 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,01421238 0,03774651 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,01421238 0,03770298 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,01421238 0,03765954 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,01421238 0,0376162 ! sulfate transport GO:0008272 12 10 0,000 0,01421238 0,03757297 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,01421238 0,03752983 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,01421238 0,03748679 ! androgen metabolic process GO:0008209 13 10 0,000 0,01421238 0,03744385 ! phospholipid efflux GO:0033700 16 10 0,000 0,01421238 0,03740101 ! hippocampus development GO:0021766 19 10 0,000 0,01421238 0,03735826 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,01421238 0,03731562 ! blood vessel remodeling GO:0001974 21 10 0,000 0,01421238 0,03727307 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,01421238 0,03723062 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,01421238 0,03718826 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,01421238 0,037146 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,01421238 0,03710384 ! pathogenesis GO:0009405 13 10 0,000 0,01421238 0,03706177 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,01421238 0,0370198 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01421238 0,03697792 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,01421238 0,03693614 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 0,01421238 0,03689445 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,01421238 0,03685285 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,01421238 0,03681135 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,01421238 0,03676994 ! melanocyte differentiation GO:0030318 15 10 0,000 0,01421238 0,03672863 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,01421238 0,03668741 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,01421238 0,03664628 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,01421238 0,03660524 ! response to X-ray GO:0010165 16 10 0,000 0,01421238 0,0365643 ! B cell proliferation GO:0042100 14 10 0,000 0,01421238 0,03652344 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,01421238 0,03648268 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,01421238 0,03644201 ! forebrain cell migration GO:0021885 17 10 0,000 0,01421238 0,03640143 ! lipid digestion GO:0044241 15 10 0,000 0,01421238 0,03636093 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,01421238 0,03632053 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,01421238 0,03628022 ! UV protection GO:0009650 14 10 0,000 0,01421238 0,03624 ! entry into host cell GO:0030260 20 10 0,000 0,01421238 0,03619987 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,01421238 0,03615982 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,01421238 0,03611987 ! negative regulation of ossification GO:0030279 19 10 0,000 0,01421238 0,03608 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,01421238 0,03604022 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,01421238 0,03600053 ! regulation of bone resorption GO:0045124 24 10 0,000 0,01421238 0,03596092 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,01421238 0,03592141 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,01421238 0,03588198 ! regulation of organ growth GO:0046620 11 10 0,000 0,01421238 0,03584263 ! response to dsRNA GO:0043331 18 10 0,000 0,01421238 0,03580337 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,01421238 0,0357642 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,01421238 0,03572511 ! embryonic axis specification GO:0000578 12 10 0,000 0,01421238 0,03568611 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,01421238 0,0356472 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,01421238 0,03560837 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,01421238 0,03556962 ! cranial nerve development GO:0021545 12 10 0,000 0,01421238 0,03553096 ! fucose catabolic process GO:0019317 16 10 0,000 0,01421238 0,03549238 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,01421238 0,03545388 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,01421238 0,03541547 ! protein sumoylation GO:0016925 12 10 0,000 0,01421238 0,03537714 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,01421238 0,0353389 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01421238 0,03530073 ! zymogen activation GO:0031638 14 10 0,000 0,01421238 0,03526265 ! salivary gland development GO:0007431 22 10 0,000 0,01421238 0,03522466 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,01421238 0,03518674 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,01421238 0,0351489 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,01421238 0,03511115 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,01421238 0,03507348 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,01421238 0,03503588 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,01421238 0,03499837 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,01421238 0,03496094 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,01421238 0,03492359 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,01421238 0,03488632 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,01421238 0,03484913 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,01421238 0,03481201 ! detection of bacterium GO:0016045 10 10 0,000 0,01421238 0,03477498 ! embryonic gut development GO:0048566 11 10 0,000 0,01421238 0,03473802 ! activation of innate immune response GO:0002218 10 10 0,000 0,01421238 0,03470115 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,01421238 0,03466435 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,01421238 0,03462763 ! developmental induction GO:0031128 13 10 0,000 0,01421238 0,03459098 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,01421238 0,03455442 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,01421238 0,03451793 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,01421238 0,03448152 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,01421238 0,03444518 ! rRNA transcription GO:0009303 17 11 0,000 0,01562291 0,03782388 ! respiratory burst GO:0045730 14 11 0,000 0,01562291 0,03778411 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,01562291 0,03774442 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,01562291 0,03770481 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,01562291 0,03766529 ! virus-host interaction GO:0019048 17 11 0,000 0,01562291 0,03762585 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 0,01562291 0,03758649 ! filopodium assembly GO:0046847 19 11 0,000 0,01562291 0,03754722 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,01562291 0,03750802 ! RNA polyadenylation GO:0043631 19 11 0,000 0,01562291 0,03746891 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,01562291 0,03742988 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,01562291 0,03739093 ! mating GO:0007618 14 11 0,000 0,01562291 0,03735207 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,01562291 0,03731328 ! T cell proliferation GO:0042098 20 11 0,000 0,01562291 0,03727457 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,01562291 0,03723595 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,01562291 0,0371974 ! bone resorption GO:0045453 16 11 0,000 0,01562291 0,03715893 ! regulated secretory pathway GO:0045055 14 11 0,000 0,01562291 0,03712054 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,01562291 0,03708224 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,01562291 0,03704401 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,01562291 0,03700586 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,01562291 0,03696779 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,01562291 0,03692979 ! syncytium formation GO:0006949 15 11 0,000 0,01562291 0,03689188 ! plasma membrane organization GO:0007009 18 11 0,000 0,01562291 0,03685404 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,01562291 0,03681628 ! focal adhesion formation GO:0048041 24 11 0,000 0,01562291 0,03677859 ! mitotic spindle organization GO:0007052 15 11 0,000 0,01562291 0,03674099 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,01562291 0,03670346 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,01562291 0,03666601 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,01562291 0,03662863 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,01562291 0,03659133 ! adult heart development GO:0007512 11 11 0,000 0,01562291 0,03655411 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,01562291 0,03651696 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,01562291 0,03647989 ! temperature homeostasis GO:0001659 16 11 0,000 0,01562291 0,03644289 ! L-glutamate transport GO:0015813 16 11 0,000 0,01562291 0,03640596 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,01562291 0,03636912 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,01562291 0,03633234 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,01562291 0,03629564 ! stem cell development GO:0048864 29 11 0,000 0,01562291 0,03625902 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,01562291 0,03622247 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,01562291 0,03618599 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,01562291 0,03614958 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,01562291 0,03611325 ! vasoconstriction GO:0042310 15 11 0,000 0,01562291 0,036077 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,01562291 0,03604081 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,01562291 0,0360047 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,01562291 0,03596866 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,01562291 0,03593269 ! ribosome assembly GO:0042255 13 11 0,000 0,01562291 0,03589679 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,01562291 0,03586097 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,01562291 0,03582521 ! chromatin silencing GO:0006342 19 11 0,000 0,01562291 0,03578953 ! nucleosome positioning GO:0016584 13 11 0,000 0,01562291 0,03575392 ! T cell homeostasis GO:0043029 20 11 0,000 0,01562291 0,03571838 ! regulation of isotype switching GO:0045191 19 11 0,000 0,01562291 0,03568291 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,01562291 0,03564751 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,01562291 0,03561218 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,01562291 0,03557692 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,01562291 0,03554173 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,01562291 0,03550661 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,01562291 0,03547156 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,01562291 0,03543658 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,01562291 0,03540166 ! male genitalia development GO:0030539 13 11 0,000 0,01562291 0,03536682 ! cholesterol efflux GO:0033344 19 11 0,000 0,01562291 0,03533204 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,01562291 0,03529734 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,01562291 0,0352627 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,01562291 0,03522812 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,01562291 0,03519362 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,01562291 0,03515919 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,01562291 0,03512482 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,01562291 0,03509051 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,01562291 0,03505628 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,01562291 0,03502211 ! lysogeny GO:0030069 18 11 0,000 0,01562291 0,03498801 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,01562291 0,03495398 ! acrosome reaction GO:0007340 13 11 0,000 0,01562291 0,03492001 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,01562291 0,0348861 ! lactation GO:0007595 20 12 0,000 0,01703149 0,03799461 ! reproductive cellular process GO:0048610 14 12 0,000 0,01703149 0,03795779 ! tRNA modification GO:0006400 14 12 0,000 0,01703149 0,03792104 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,01703149 0,03788437 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,01703149 0,03784777 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,01703149 0,03781123 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,01703149 0,03777477 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,01703149 0,03773838 ! non-recombinational repair GO:0000726 19 12 0,000 0,01703149 0,03770206 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,01703149 0,03766581 ! peroxisomal transport GO:0043574 21 12 0,000 0,01703149 0,03762962 ! cartilage condensation GO:0001502 18 12 0,000 0,01703149 0,03759351 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,01703149 0,03755747 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,01703149 0,03752149 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,01703149 0,03748559 ! heart looping GO:0001947 15 12 0,000 0,01703149 0,03744975 ! palate development GO:0060021 15 12 0,000 0,01703149 0,03741398 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,01703149 0,03737828 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,01703149 0,03734265 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,01703149 0,03730708 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,01703149 0,03727159 ! arginine metabolic process GO:0006525 13 12 0,000 0,01703149 0,03723616 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,01703149 0,0372008 ! methionine metabolic process GO:0006555 13 12 0,000 0,01703149 0,0371655 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,01703149 0,03713027 ! Golgi organization GO:0007030 18 12 0,000 0,01703149 0,03709511 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,01703149 0,03706002 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,01703149 0,03702499 ! monoamine transport GO:0015844 13 12 0,000 0,01703149 0,03699003 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01703149 0,03695513 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,01703149 0,0369203 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,01703149 0,03688553 ! L-amino acid transport GO:0015807 20 12 0,000 0,01703149 0,03685084 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,01703149 0,0368162 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,01703149 0,03678163 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,01703149 0,03674713 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,01703149 0,03671269 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,01703149 0,03667831 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,01703149 0,036644 ! cerebellum development GO:0021549 13 12 0,000 0,01703149 0,03660976 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,01703149 0,03657557 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,01703149 0,03654145 ! histone acetylation GO:0016573 23 12 0,000 0,01703149 0,0365074 ! histone methylation GO:0016571 15 12 0,000 0,01703149 0,03647341 ! autonomic nervous system development GO:0048483 23 12 0,000 0,01703149 0,03643948 ! gland morphogenesis GO:0022612 23 12 0,000 0,01703149 0,03640561 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,01703149 0,03637181 ! peptidyl-lysine modification GO:0018205 18 12 0,000 0,01703149 0,03633807 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,01703149 0,03630439 ! response to gamma radiation GO:0010332 20 12 0,000 0,01703149 0,03627078 ! regulation of epidermis development GO:0045682 17 12 0,000 0,01703149 0,03623722 ! intestinal absorption GO:0050892 19 12 0,000 0,01703149 0,03620373 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,01703149 0,0361703 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,01703149 0,03613694 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,01703149 0,03610363 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,01703149 0,03607038 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,01703149 0,0360372 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,01703149 0,03600408 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,01703149 0,03597102 ! microspike assembly GO:0030035 23 12 0,000 0,01703149 0,03593802 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,01703149 0,03590508 ! response to cold GO:0009409 14 12 0,000 0,01703149 0,0358722 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 0,01843815 0,03879939 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,01843815 0,03876393 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,01843815 0,03872853 ! cGMP metabolic process GO:0046068 16 13 0,000 0,01843815 0,03869319 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,01843815 0,03865792 ! water transport GO:0006833 17 13 0,000 0,01843815 0,03862271 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,01843815 0,03858757 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,01843815 0,03855249 ! lipid localization GO:0010876 24 13 0,000 0,01843815 0,03851747 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,01843815 0,03848252 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,01843815 0,03844763 ! organelle fusion GO:0048284 28 13 0,000 0,01843815 0,03841281 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,01843815 0,03837804 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,01843815 0,03834334 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,01843815 0,03830871 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,01843815 0,03827413 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,01843815 0,03823962 ! response to hexose stimulus GO:0009746 19 13 0,000 0,01843815 0,03820517 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,01843815 0,03817078 ! glutamate metabolic process GO:0006536 18 13 0,000 0,01843815 0,03813645 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,01843815 0,03810219 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,01843815 0,03806799 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,01843815 0,03803385 ! NAD metabolic process GO:0019674 21 13 0,000 0,01843815 0,03799977 ! exocrine system development GO:0035272 27 13 0,000 0,01843815 0,03796575 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,01843815 0,03793179 ! bone mineralization GO:0030282 15 13 0,000 0,01843815 0,03789789 ! regulation of exocytosis GO:0017157 17 13 0,000 0,01843815 0,03786405 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,01843815 0,03783027 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,01843815 0,03779656 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,01843815 0,0377629 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,01843815 0,0377293 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,01843815 0,03769577 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,01843815 0,03766229 ! genitalia development GO:0048806 15 13 0,000 0,01843815 0,03762887 ! regulation of cellular pH GO:0030641 20 13 0,000 0,01843815 0,03759551 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 0,01843815 0,03756221 ! cellular pigmentation GO:0033059 24 13 0,000 0,01843815 0,03752897 ! tissue regeneration GO:0042246 21 13 0,000 0,01843815 0,03749579 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,01843815 0,03746267 ! cofactor transport GO:0051181 19 13 0,000 0,01843815 0,0374296 ! NADP metabolic process GO:0006739 18 13 0,000 0,01843815 0,03739659 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,01843815 0,03736365 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,01843815 0,03733076 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,01843815 0,03729792 ! gas transport GO:0015669 18 13 0,000 0,01843815 0,03726515 ! regulation of RNA stability GO:0043487 28 13 0,000 0,01843815 0,03723243 ! heme biosynthetic process GO:0006783 20 13 0,000 0,01843815 0,03719977 ! regulation of axon extension GO:0030516 23 13 0,000 0,01843815 0,03716717 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,01843815 0,03713462 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,01843815 0,03710213 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,01843815 0,0370697 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,01843815 0,03703733 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,01843815 0,03700501 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,01843815 0,03697274 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,01984287 0,03975487 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,01984287 0,03972027 ! superoxide anion generation GO:0042554 18 14 0,000 0,01984287 0,03968573 ! neuron maturation GO:0042551 21 14 0,000 0,01984287 0,03965125 ! regulation of S phase GO:0033261 18 14 0,000 0,01984287 0,03961683 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,01984287 0,03958247 ! myotube differentiation GO:0014902 21 14 0,000 0,01984287 0,03954817 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 0,01984287 0,03951393 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,01984287 0,03947975 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,01984287 0,03944563 ! inositol metabolic process GO:0006020 20 14 0,000 0,01984287 0,03941157 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,01984287 0,03937756 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,01984287 0,03934361 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,01984287 0,03930973 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,01984287 0,0392759 ! gene silencing by RNA GO:0031047 20 14 0,000 0,01984287 0,03924213 ! response to cAMP GO:0051591 19 14 0,000 0,01984287 0,03920841 ! limbic system development GO:0021761 25 14 0,000 0,01984287 0,03917476 ! startle response GO:0001964 21 14 0,000 0,01984287 0,03914116 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,01984287 0,03910762 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,01984287 0,03907414 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,01984287 0,03904071 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,01984287 0,03900734 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,01984287 0,03897403 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,01984287 0,03894078 ! glycine metabolic process GO:0006544 22 14 0,000 0,01984287 0,03890758 ! pituitary gland development GO:0021983 23 14 0,000 0,01984287 0,03887444 ! cellular response to starvation GO:0009267 21 14 0,000 0,01984287 0,03884136 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,01984287 0,03880833 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,01984287 0,03877535 ! regulation of heart rate GO:0002027 23 14 0,000 0,01984287 0,03874244 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,01984287 0,03870958 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,01984287 0,03867677 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,01984287 0,03864402 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,01984287 0,03861133 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,01984287 0,03857869 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,01984287 0,03854611 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,01984287 0,03851358 ! axon cargo transport GO:0008088 27 14 0,000 0,01984287 0,03848111 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,01984287 0,03844869 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,01984287 0,03841632 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,01984287 0,03838401 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,01984287 0,03835176 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,01984287 0,03831956 ! mRNA splice site selection GO:0006376 26 14 0,000 0,01984287 0,03828741 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,01984287 0,03825532 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,01984287 0,03822328 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,01984287 0,03819129 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,01984287 0,03815936 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,01984287 0,03812748 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,01984287 0,03809565 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,01984287 0,03806388 ! muscle maintenance GO:0046716 19 14 0,000 0,01984287 0,03803216 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,01984287 0,03800049 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,01984287 0,03796888 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,01984287 0,03793732 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,01984287 0,03790581 ! cell killing GO:0001906 20 14 0,000 0,01984287 0,03787435 ! release of cytochrome c from mitochondria GO:0001836 23 14 0,000 0,01984287 0,03784295 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,01984287 0,03781159 ! cilium assembly GO:0042384 20 14 0,000 0,01984287 0,03778029 ! peptide hormone secretion GO:0030072 23 14 0,000 0,01984287 0,03774904 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,02124566 0,0403843 ! positive regulation of cell size GO:0045793 20 15 0,000 0,02124566 0,04035096 ! metencephalon development GO:0022037 19 15 0,000 0,02124566 0,04031766 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,02124566 0,04028443 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,02124566 0,04025124 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,02124566 0,04021811 ! skin development GO:0043588 25 15 0,000 0,02124566 0,04018504 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,02124566 0,04015202 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,02124566 0,04011905 ! lipid phosphorylation GO:0046834 23 15 0,000 0,02124566 0,04008614 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,02124566 0,04005329 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,02124566 0,04002048 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,02124566 0,03998773 ! bile acid metabolic process GO:0008206 22 15 0,000 0,02124566 0,03995504 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,02124566 0,03992239 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,02124566 0,0398898 ! adult walking behavior GO:0007628 25 15 0,000 0,02124566 0,03985727 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,02124566 0,03982478 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,02124566 0,03979235 ! myoblast differentiation GO:0045445 27 15 0,000 0,02124566 0,03975997 ! centrosome cycle GO:0007098 16 15 0,000 0,02124566 0,03972765 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,02124566 0,03969538 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,02124566 0,03966316 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,02124566 0,03963099 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,02124566 0,03959887 ! cerebral cortex development GO:0021987 29 15 0,000 0,02124566 0,03956681 ! response to osmotic stress GO:0006970 22 15 0,000 0,02124566 0,0395348 ! vesicle coating GO:0006901 25 15 0,000 0,02124566 0,03950284 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,02124566 0,03947093 ! DNA integration GO:0015074 22 15 0,000 0,02124566 0,03943907 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,02124566 0,03940727 ! peptide secretion GO:0002790 27 15 0,000 0,02124566 0,03937551 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,02124566 0,03934381 ! regulation of vasodilation GO:0042312 24 15 0,000 0,02124566 0,03931216 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,02124566 0,03928055 ! neuron recognition GO:0008038 22 15 0,000 0,02124566 0,039249 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,02124566 0,0392175 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,02124566 0,03918605 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,02124566 0,03915465 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,02124566 0,03912331 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,02124566 0,03909201 ! biomineral formation GO:0031214 18 15 0,000 0,02124566 0,03906076 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,02124566 0,03902956 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,02124566 0,03899841 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,02124566 0,03896731 ! dopamine metabolic process GO:0042417 30 15 0,000 0,02124566 0,03893626 ! organic cation transport GO:0015695 19 15 0,000 0,02124566 0,03890526 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,02124566 0,03887431 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,02124566 0,03884341 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,02124566 0,03881256 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,02124566 0,03878175 ! defense response to virus GO:0051607 27 15 0,000 0,02124566 0,038751 ! peptide hormone processing GO:0016486 19 15 0,000 0,02124566 0,03872029 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,02124566 0,03868963 ! protein secretion GO:0009306 27 16 0,000 0,02264652 0,04120806 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,02264652 0,04117549 ! hormone secretion GO:0046879 25 16 0,000 0,02264652 0,04114296 ! bone remodeling GO:0046849 24 16 0,000 0,02264652 0,04111049 ! endothelial cell migration GO:0043542 22 16 0,000 0,02264652 0,04107807 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,02264652 0,0410457 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,02264652 0,04101338 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,02264652 0,04098111 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,02264652 0,04094889 ! glial cell development GO:0021782 24 16 0,000 0,02264652 0,04091673 ! patterning of blood vessels GO:0001569 24 16 0,000 0,02264652 0,04088461 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,02264652 0,04085254 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,02264652 0,04082053 ! protein polyubiquitination GO:0000209 26 16 0,000 0,02264652 0,04078856 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,02264652 0,04075664 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,02264652 0,04072478 ! fructose metabolic process GO:0006000 20 16 0,000 0,02264652 0,04069296 ! regulation of protein binding GO:0043393 27 16 0,000 0,02264652 0,0406612 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,02264652 0,04062948 ! protein export from nucleus GO:0006611 24 16 0,000 0,02264652 0,04059781 ! negative regulation of immune response GO:0050777 28 16 0,000 0,02264652 0,04056619 ! DNA replication initiation GO:0006270 25 16 0,000 0,02264652 0,04053462 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,02264652 0,0405031 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,02264652 0,04047163 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,02264652 0,04044021 ! diencephalon development GO:0021536 25 16 0,000 0,02264652 0,04040884 ! oogenesis GO:0048477 23 16 0,000 0,02264652 0,04037751 ! neural crest cell migration GO:0001755 24 16 0,000 0,02264652 0,04034624 ! G1 phase GO:0051318 27 16 0,000 0,02264652 0,04031501 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,02264652 0,04028383 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,02264652 0,0402527 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,02264652 0,04022162 ! steroid catabolic process GO:0006706 22 16 0,000 0,02264652 0,04019058 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,02264652 0,04015959 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,02264652 0,04012865 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,02264652 0,04009776 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,02264652 0,04006692 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,02264652 0,04003612 ! sperm-egg recognition GO:0035036 16 16 0,000 0,02264652 0,04000537 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,02264652 0,03997467 ! nerve development GO:0021675 18 16 0,000 0,02264652 0,03994401 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,02264652 0,0399134 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,02264652 0,03988284 ! negative regulation of translation GO:0017148 22 16 0,000 0,02264652 0,03985233 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,02404546 0,04228176 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,02404546 0,04224946 ! negative regulation of defense response GO:0031348 19 17 0,000 0,02404546 0,04221721 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,02404546 0,04218501 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,02404546 0,04215286 ! glycerol metabolic process GO:0006071 20 17 0,000 0,02404546 0,04212075 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,02404546 0,0420887 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,02404546 0,04205669 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,02404546 0,04202473 ! signal complex assembly GO:0007172 29 17 0,000 0,02404546 0,04199282 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,02404546 0,04196096 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,02404546 0,04192915 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,02404546 0,04189738 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,02404546 0,04186567 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,02404546 0,041834 ! memory GO:0007613 25 17 0,000 0,02404546 0,04180238 ! keratinization GO:0031424 17 17 0,000 0,02404546 0,04177081 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,02404546 0,04173928 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,02404546 0,0417078 ! retinoid metabolic process GO:0001523 22 17 0,000 0,02404546 0,04167637 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,02404546 0,04164499 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,02404546 0,04161365 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,02404546 0,04158237 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,02404546 0,04155112 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,02404546 0,04151993 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,02404546 0,04148878 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 0,000 0,02404546 0,04145768 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,02404546 0,04142663 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,02404546 0,04139562 ! membrane budding GO:0006900 29 17 0,000 0,02404546 0,04136466 ! heme metabolic process GO:0042168 27 17 0,000 0,02404546 0,04133374 ! actin filament bundle formation GO:0051017 26 17 0,000 0,02404546 0,04130287 ! neuromuscular junction development GO:0007528 23 17 0,000 0,02404546 0,04127205 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,02404546 0,04124127 ! body fluid secretion GO:0007589 27 17 0,000 0,02404546 0,04121054 ! stem cell differentiation GO:0048863 36 17 0,000 0,02404546 0,04117986 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,02404546 0,04114922 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,02404546 0,04111862 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,02404546 0,04108807 ! sensory perception of pain GO:0019233 23 17 0,000 0,02404546 0,04105757 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,02404546 0,04102711 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,02404546 0,0409967 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,02404546 0,04096633 ! synaptogenesis GO:0007416 24 17 0,000 0,02404546 0,04093601 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,02404546 0,04090573 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,02404546 0,0408755 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,02404546 0,04084531 ! cell-cell junction organization GO:0045216 25 17 0,000 0,02404546 0,04081516 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,02404546 0,04078506 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,02404546 0,04075501 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,02404546 0,040725 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,02404546 0,04069503 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,02404546 0,04066511 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,02404546 0,04063523 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,02544247 0,04296452 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,02544247 0,042933 ! positive regulation of translation GO:0045727 28 18 0,000 0,02544247 0,04290153 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,02544247 0,0428701 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,02544247 0,04283871 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,02544247 0,04280737 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,02544247 0,04277608 ! cAMP metabolic process GO:0046058 33 18 0,000 0,02544247 0,04274484 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,02544247 0,04271364 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,02544247 0,04268248 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,02544247 0,04265137 ! axis specification GO:0009798 26 18 0,000 0,02544247 0,04262031 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,02544247 0,04258929 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,02544247 0,04255831 ! pancreas development GO:0031016 26 18 0,000 0,02544247 0,04252738 ! apoptotic mitochondrial changes GO:0008637 29 18 0,000 0,02544247 0,0424965 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,02544247 0,04246566 ! glutamine metabolic process GO:0006541 23 18 0,000 0,02544247 0,04243487 ! response to retinoic acid GO:0032526 25 18 0,000 0,02544247 0,04240412 ! pigmentation during development GO:0048066 31 18 0,000 0,02544247 0,04237341 ! central nervous system neuron development GO:0021954 30 18 0,000 0,02544247 0,04234275 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,02544247 0,04231213 ! fucose metabolic process GO:0006004 26 18 0,000 0,02544247 0,04228156 ! response to fungus GO:0009620 19 18 0,000 0,02544247 0,04225103 ! peptide cross-linking GO:0018149 31 18 0,000 0,02544247 0,04222055 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,02544247 0,04219011 ! heart process GO:0003015 27 18 0,000 0,02544247 0,04215971 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,02544247 0,04212936 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,02544247 0,04209905 ! visual learning GO:0008542 35 18 0,000 0,02544247 0,04206879 ! somitogenesis GO:0001756 24 18 0,000 0,02544247 0,04203856 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,02544247 0,04200839 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,02544247 0,04197825 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,02544247 0,04194816 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,02544247 0,04191811 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,02544247 0,0418881 ! vitamin transport GO:0051180 24 18 0,000 0,02544247 0,04185814 ! hormone transport GO:0009914 27 18 0,000 0,02544247 0,04182822 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,02544247 0,04179834 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,02544247 0,04176851 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,02544247 0,04173872 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,02544247 0,04170897 ! cell-cell recognition GO:0009988 20 18 0,000 0,02544247 0,04167926 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,02544247 0,0416496 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,02544247 0,04161997 ! regulation of glucose import GO:0046324 21 18 0,000 0,02544247 0,04159039 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,02544247 0,04156085 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,02544247 0,04153136 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,02544247 0,0415019 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,02544247 0,04147249 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,02683757 0,04371558 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,02683757 0,04368464 ! positive regulation of fibroblast proliferation GO:0048146 27 19 0,000 0,02683757 0,04365375 ! positive regulation of ossification GO:0045778 30 19 0,000 0,02683757 0,0436229 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,02683757 0,04359209 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,02683757 0,04356133 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,02683757 0,04353061 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,02683757 0,04349993 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,02683757 0,0434693 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,02683757 0,0434387 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,02683757 0,04340816 ! regeneration GO:0031099 32 19 0,000 0,02683757 0,04337765 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,02683757 0,04334719 ! response to alkaloid GO:0043279 32 19 0,000 0,02683757 0,04331677 ! sensory perception of taste GO:0050909 23 19 0,000 0,02683757 0,0432864 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,02683757 0,04325606 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 0,000 0,02683757 0,04322577 ! smooth muscle contraction GO:0006939 36 19 0,000 0,02683757 0,04319552 ! peroxisome organization GO:0007031 29 19 0,000 0,02683757 0,04316531 ! digestive system process GO:0022600 30 19 0,000 0,02683757 0,04313515 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,02683757 0,04310503 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,02683757 0,04307495 ! response to vitamin A GO:0033189 26 19 0,000 0,02683757 0,04304491 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,02683757 0,04301491 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,02683757 0,04298496 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,02683757 0,04295505 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,02683757 0,04292517 ! response to starvation GO:0042594 30 19 0,000 0,02683757 0,04289534 ! sex determination GO:0007530 29 19 0,000 0,02683757 0,04286556 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,02683757 0,04283581 ! plasma membrane fusion GO:0045026 23 19 0,000 0,02683757 0,0428061 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,02683757 0,04277644 ! cytolysis GO:0019835 20 19 0,000 0,02683757 0,04274681 ! renal system process GO:0003014 35 19 0,000 0,02683757 0,04271723 ! vasodilation GO:0042311 33 19 0,000 0,02683757 0,04268769 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,02683757 0,04265819 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,02683757 0,04262873 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,02683757 0,04259931 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,02683757 0,04256993 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,02683757 0,04254059 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,02683757 0,04251129 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,02683757 0,04248204 ! sarcomere organization GO:0045214 23 19 0,000 0,02683757 0,04245282 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,02683757 0,04242364 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,02683757 0,04239451 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,02683757 0,04236541 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,02683757 0,04233635 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,02683757 0,04230733 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,02683757 0,04227836 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,02683757 0,04224942 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,02683757 0,04222052 ! protein stabilization GO:0050821 26 19 0,000 0,02683757 0,04219166 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,02823074 0,04435158 ! iron ion transport GO:0006826 37 20 0,000 0,02823074 0,0443213 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,02823074 0,04429107 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,02823074 0,04426088 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,02823074 0,04423073 ! response to vitamin GO:0033273 29 20 0,000 0,02823074 0,04420062 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,02823074 0,04417055 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,02823074 0,04414052 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,02823074 0,04411054 ! spinal cord development GO:0021510 31 20 0,000 0,02823074 0,04408059 ! response to ethanol GO:0045471 37 20 0,000 0,02823074 0,04405068 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,02823074 0,04402082 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 0,000 0,02823074 0,04399099 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,02823074 0,04396121 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,02823074 0,04393147 ! chromosome condensation GO:0030261 31 20 0,000 0,02823074 0,04390176 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,02823074 0,0438721 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,02823074 0,04384248 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,02823074 0,04381289 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,02823074 0,04378335 ! pallium development GO:0021543 38 20 0,000 0,02823074 0,04375385 ! DNA modification GO:0006304 28 20 0,000 0,02823074 0,04372438 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,02823074 0,04369496 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,02823074 0,04366557 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,02823074 0,04363623 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,02823074 0,04360692 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,02823074 0,04357766 ! positive regulation of B cell activation GO:0050871 31 20 0,000 0,02823074 0,04354843 ! collagen catabolic process GO:0030574 25 20 0,000 0,02823074 0,04351924 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,02823074 0,04349009 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,02823074 0,04346098 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,02823074 0,04343191 ! alditol metabolic process GO:0019400 24 20 0,000 0,02823074 0,04340288 ! actin filament-based movement GO:0030048 34 20 0,000 0,02823074 0,04337389 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,02962201 0,04548105 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,02962201 0,04545071 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,02962201 0,04542041 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,02962201 0,04539015 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 0,000 0,02962201 0,04535993 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,02962201 0,04532975 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,02962201 0,04529961 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,02962201 0,04526951 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,02962201 0,04523945 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,02962201 0,04520943 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,02962201 0,04517945 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,02962201 0,04514951 ! protein amino acid acylation GO:0043543 37 21 0,000 0,02962201 0,04511961 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,02962201 0,04508975 ! vesicle docking GO:0048278 27 21 0,000 0,02962201 0,04505993 ! phototransduction GO:0007602 25 21 0,000 0,02962201 0,04503015 ! dendrite development GO:0016358 35 21 0,000 0,02962201 0,0450004 ! visual behavior GO:0007632 39 21 0,000 0,02962201 0,0449707 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,02962201 0,04494104 ! ovarian follicle development GO:0001541 30 21 0,000 0,02962201 0,04491141 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,02962201 0,04488183 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,02962201 0,04485228 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,02962201 0,04482277 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,02962201 0,0447933 ! cell aging GO:0007569 32 21 0,000 0,02962201 0,04476387 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,02962201 0,04473448 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,02962201 0,04470513 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,02962201 0,04467581 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,02962201 0,04464654 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,02962201 0,0446173 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,02962201 0,0445881 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,02962201 0,04455894 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,02962201 0,04452981 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,02962201 0,04450073 ! fatty acid transport GO:0015908 30 21 0,000 0,02962201 0,04447168 ! immunoglobulin production GO:0002377 33 21 0,000 0,02962201 0,04444267 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,02962201 0,0444137 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,02962201 0,04438476 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,02962201 0,04435587 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,02962201 0,04432701 ! cellular response to extracellular stimulus GO:0031668 32 21 0,000 0,02962201 0,04429819 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,02962201 0,0442694 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,02962201 0,04424066 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,02962201 0,04421195 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,02962201 0,04418328 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,02962201 0,04415464 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,02962201 0,04412604 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,02962201 0,04409748 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,02962201 0,04406896 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,02962201 0,04404047 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,02962201 0,04401202 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,03101136 0,04604656 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,03101136 0,04601685 ! regulation of fibroblast proliferation GO:0048145 35 22 0,000 0,03101136 0,04598718 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,03101136 0,04595755 ! viral genome replication GO:0019079 29 22 0,000 0,03101136 0,04592796 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,03101136 0,0458984 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,03101136 0,04586889 ! leukocyte adhesion GO:0007159 38 22 0,000 0,03101136 0,04583941 ! molting cycle process GO:0022404 40 22 0,000 0,03101136 0,04580997 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,03101136 0,04578056 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,03101136 0,0457512 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,03101136 0,04572187 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,03101136 0,04569258 ! vasculogenesis GO:0001570 33 22 0,000 0,03101136 0,04566333 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,03101136 0,04563411 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,03101136 0,04560494 GO:0010810|regulation of cell-substrate adhesion, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,03101136 0,04557579 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,03101136 0,04554669 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,03101136 0,04551763 ! lysosome organization GO:0007040 37 22 0,000 0,03101136 0,0454886 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,03101136 0,0454596 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,03101136 0,04543065 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,03101136 0,04540173 ! regulation of behavior GO:0050795 38 22 0,000 0,03101136 0,04537285 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,03101136 0,045344 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,03101136 0,0453152 ! membrane depolarization GO:0051899 35 22 0,000 0,03101136 0,04528642 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,03101136 0,04525769 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,03101136 0,04522899 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,03101136 0,04520033 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,03101136 0,0451717 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,03101136 0,04514311 ! blastocyst development GO:0001824 37 22 0,000 0,03101136 0,04511456 ! neural tube closure GO:0001843 33 22 0,000 0,03101136 0,04508604 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,03101136 0,04505756 ! protein tetramerization GO:0051262 39 22 0,000 0,03101136 0,04502912 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,0323988 0,04701403 ! neuron fate commitment GO:0048663 32 23 0,000 0,0323988 0,04698438 ! embryonic pattern specification GO:0009880 31 23 0,000 0,0323988 0,04695478 ! positive regulation of cell adhesion GO:0045785 37 23 0,000 0,0323988 0,04692521 ! myelination GO:0042552 35 23 0,000 0,0323988 0,04689568 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,0323988 0,04686618 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,0323988 0,04683673 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,0323988 0,04680731 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,0323988 0,04677792 ! vesicle targeting GO:0006903 32 23 0,000 0,0323988 0,04674858 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,0323988 0,04671927 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,0323988 0,04669 ! osteoblast differentiation GO:0001649 40 23 0,000 0,0323988 0,04666076 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,0323988 0,04663156 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,0323988 0,0466024 ! interaction with host GO:0051701 37 23 0,000 0,0323988 0,04657327 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,0323988 0,04654418 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,0323988 0,04651513 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,0323988 0,04648611 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,0323988 0,04645713 ! negative regulation of phosphorylation GO:0042326 41 23 0,000 0,0323988 0,04642818 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,0323988 0,04639927 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,0323988 0,0463704 ! cell fate determination GO:0001709 45 23 0,000 0,0323988 0,04634156 ! pentose metabolic process GO:0019321 31 23 0,000 0,0323988 0,04631276 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,0323988 0,046284 ! spermatid development GO:0007286 33 23 0,000 0,0323988 0,04625527 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,0323988 0,04622657 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,0323988 0,04619791 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,0323988 0,04616929 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,0323988 0,0461407 ! telomere organization GO:0032200 32 23 0,000 0,0323988 0,04611215 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,0323988 0,04608363 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,0323988 0,04605515 ! regulation of amine transport GO:0051952 38 23 0,000 0,0323988 0,0460267 ! liver development GO:0001889 40 23 0,000 0,0323988 0,04599829 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,03378433 0,04793582 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,03378433 0,04790626 ! initiation of viral infection GO:0019059 42 24 0,000 0,03378433 0,04787675 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,03378433 0,04784727 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,03378433 0,04781782 ! superoxide metabolic process GO:0006801 32 24 0,000 0,03378433 0,04778841 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,03378433 0,04775904 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,03378433 0,04772971 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,03378433 0,04770041 ! sperm motility GO:0030317 27 24 0,000 0,03378433 0,04767114 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,03378433 0,04764191 ! vacuole organization GO:0007033 39 24 0,000 0,03378433 0,04761272 ! receptor metabolic process GO:0043112 37 24 0,000 0,03378433 0,04758356 ! neural crest cell development GO:0014032 39 24 0,000 0,03378433 0,04755444 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,03378433 0,04752536 ! primary neural tube formation GO:0014020 35 24 0,000 0,03378433 0,04749631 ! negative regulation of cell development GO:0010721 56 24 0,000 0,03378433 0,04746729 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,03378433 0,04743831 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,03378433 0,04740937 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,03378433 0,04738046 ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,03378433 0,04735159 ! glutathione metabolic process GO:0006749 29 24 0,000 0,03378433 0,04732275 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,03378433 0,04729395 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,03378433 0,04726518 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,03378433 0,04723645 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,03516796 0,04914113 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,03516796 0,0491113 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,03516796 0,0490815 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,03516796 0,04905173 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,03516796 0,049022 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,03516796 0,04899231 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 0,000 0,03516796 0,04896266 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,03516796 0,04893303 ! peptide transport GO:0015833 43 25 0,000 0,03516796 0,04890345 ! male gonad development GO:0008584 33 25 0,000 0,03516796 0,0488739 ! iron ion homeostasis GO:0055072 39 25 0,000 0,03516796 0,04884439 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,03516796 0,04881491 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,03516796 0,04878547 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,03516796 0,04875606 ! phospholipid transport GO:0015914 35 25 0,000 0,03516796 0,04872669 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,03516796 0,04869735 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,03516796 0,04866805 ! detection of light stimulus GO:0009583 30 25 0,000 0,03516796 0,04863879 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,03516796 0,04860956 GO:0045840|positive regulation of mitosis, ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,03516796 0,04858036 ! leukocyte proliferation GO:0070661 39 25 0,000 0,03516796 0,0485512 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,03516796 0,04852208 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,03654969 0,05039825 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,03654969 0,05036805 ! translational initiation GO:0006413 43 26 0,000 0,03654969 0,05033789 ! regulation of pH GO:0006885 36 26 0,000 0,03654969 0,05030777 ! circadian rhythm GO:0007623 42 26 0,000 0,03654969 0,05027768 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,03654969 0,05024763 ! post-embryonic development GO:0009791 42 26 0,000 0,03654969 0,05021761 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,03654969 0,05018763 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,03654969 0,05015768 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,03654969 0,05012777 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,03654969 0,0500979 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,03654969 0,05006806 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,03654969 0,05003826 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,03654969 0,05000849 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,03654969 0,04997876 ! regulation of coagulation GO:0050818 39 26 0,000 0,03654969 0,04994907 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,03792951 0,05180397 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,03792951 0,05177322 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,03792951 0,05174251 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,03792951 0,05171184 ! membrane docking GO:0022406 39 27 0,000 0,03792951 0,05168121 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,03792951 0,05165061 ! catechol metabolic process GO:0009712 43 27 0,000 0,03792951 0,05162005 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,03792951 0,05158952 ! acute-phase response GO:0006953 42 27 0,000 0,03792951 0,05155903 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,03792951 0,05152858 ! myofibril assembly GO:0030239 36 27 0,000 0,03792951 0,05149816 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,03792951 0,05146778 ! response to ionizing radiation GO:0010212 47 27 0,000 0,03792951 0,05143743 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,03792951 0,05140712 ! natural killer cell activation GO:0030101 35 27 0,000 0,03792951 0,05137684 ! lipid oxidation GO:0034440 38 27 0,000 0,03792951 0,0513466 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,03792951 0,0513164 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,03792951 0,05128623 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,03792951 0,0512561 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,03792951 0,051226 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,03792951 0,05119594 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,03792951 0,05116591 ! gene silencing GO:0016458 41 27 0,000 0,03792951 0,05113592 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,03930744 0,05296258 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,03930744 0,05293157 ! phenol metabolic process GO:0018958 44 28 0,000 0,03930744 0,0529006 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,03930744 0,05286966 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,03930744 0,05283876 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,03930744 0,0528079 ! cell junction assembly GO:0034329 56 28 0,000 0,03930744 0,05277707 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,03930744 0,05274628 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,03930744 0,05271552 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,03930744 0,0526848 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,03930744 0,05265412 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,03930744 0,05262347 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,03930744 0,05259285 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,03930744 0,05256228 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,03930744 0,05253174 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,03930744 0,05250123 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,03930744 0,05247076 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,03930744 0,05244032 ! mesoderm formation GO:0001707 46 28 0,000 0,03930744 0,05240992 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,03930744 0,05237956 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,03930744 0,05234923 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,03930744 0,05231893 ! ensheathment of neurons GO:0007272 43 28 0,000 0,03930744 0,05228867 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,03930744 0,05225845 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,03930744 0,05222826 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,03930744 0,0521981 ! neural tube formation GO:0001841 41 28 0,000 0,03930744 0,05216798 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,03930744 0,0521379 ! placenta development GO:0001890 37 28 0,000 0,03930744 0,05210785 ! regulation of B cell activation GO:0050864 42 28 0,000 0,03930744 0,05207783 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,04068348 0,05386989 ! regulation of innate immune response GO:0045088 38 29 0,000 0,04068348 0,05383889 ! ovulation cycle process GO:0022602 41 29 0,000 0,04068348 0,05380793 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,04068348 0,05377701 ! protein targeting to membrane GO:0006612 53 29 0,000 0,04068348 0,05374612 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,04068348 0,05371527 ! mismatch repair GO:0006298 34 29 0,000 0,04068348 0,05368445 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,04068348 0,05365367 ! muscle cell development GO:0055001 38 29 0,000 0,04068348 0,05362292 ! formation of primary germ layer GO:0001704 48 29 0,000 0,04068348 0,05359221 ! telencephalon development GO:0021537 52 29 0,000 0,04068348 0,05356153 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,04068348 0,05353089 ! eye morphogenesis GO:0048592 51 29 0,000 0,04068348 0,05350028 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,04068348 0,05346971 ! tissue homeostasis GO:0001894 42 29 0,000 0,04068348 0,05343918 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,04205762 0,05521263 ! collagen metabolic process GO:0032963 40 30 0,000 0,04205762 0,05518113 ! organic anion transport GO:0015711 51 30 0,000 0,04205762 0,05514967 ! cholesterol transport GO:0030301 46 30 0,000 0,04205762 0,05511825 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,04205762 0,05508686 ! spliceosome assembly GO:0000245 49 30 0,000 0,04205762 0,05505551 ! spindle organization GO:0007051 37 30 0,000 0,04205762 0,05502419 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,04205762 0,05499291 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,04205762 0,05496166 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,04205762 0,05493045 ! ceramide metabolic process GO:0006672 43 30 0,000 0,04205762 0,05489928 ! ovulation cycle GO:0042698 43 30 0,000 0,04205762 0,05486814 ! hindbrain development GO:0030902 45 30 0,000 0,04205762 0,05483703 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,04205762 0,05480596 ! adult locomotory behavior GO:0008344 47 30 0,000 0,04205762 0,05477493 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,04205762 0,05474393 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,04205762 0,05471297 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,04205762 0,05468204 ! response to heat GO:0009408 41 30 0,000 0,04205762 0,05465114 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,04205762 0,05462029 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,04205762 0,05458946 ! negative regulation of secretion GO:0051048 49 31 0,000 0,04342987 0,05633881 ! mammary gland development GO:0030879 57 31 0,000 0,04342987 0,05630705 ! glial cell differentiation GO:0010001 55 31 0,000 0,04342987 0,05627533 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,04342987 0,05624364 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,04342987 0,05621199 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,04342987 0,05618038 ! odontogenesis GO:0042476 50 31 0,000 0,04342987 0,0561488 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,04342987 0,05611725 ! segmentation GO:0035282 41 31 0,000 0,04342987 0,05608574 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,04342987 0,05605427 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,04342987 0,05602283 ! metanephros development GO:0001656 58 31 0,000 0,04342987 0,05599143 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,04342987 0,05596006 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,04342987 0,05592873 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,04342987 0,05589743 ! cell fate specification GO:0001708 37 31 0,000 0,04342987 0,05586617 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,04342987 0,05583494 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,04342987 0,05580375 ! RNA modification GO:0009451 40 31 0,000 0,04342987 0,05577259 ! regulation of muscle development GO:0048634 48 32 0,000 0,04480024 0,05750031 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,04480024 0,05746824 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,04480024 0,0574362 ! meiosis I GO:0007127 52 32 0,000 0,04480024 0,05740421 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,04480024 0,05737224 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,04480024 0,05734032 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,04480024 0,05730843 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,04480024 0,05727657 ! peripheral nervous system development GO:0007422 53 32 0,000 0,04480024 0,05724475 ! regulation of protein stability GO:0031647 48 32 0,000 0,04480024 0,05721296 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,04480024 0,05718121 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,04480024 0,0571495 ! cytokine production GO:0001816 44 32 0,000 0,04480024 0,05711782 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,04480024 0,05708618 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,04480024 0,05705457 ! vesicle localization GO:0051648 47 32 0,000 0,04480024 0,05702299 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,04616872 0,05873233 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,04616872 0,05869986 ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,04616872 0,05866743 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,04616872 0,05863504 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,04616872 0,05860268 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,04616872 0,05857036 ! sister chromatid segregation GO:0000819 46 33 0,000 0,04616872 0,05853807 ! ear morphogenesis GO:0042471 42 33 0,000 0,04616872 0,05850582 ! actomyosin structure organization GO:0031032 43 33 0,000 0,04616872 0,0584736 ! cell junction organization GO:0034330 63 33 0,000 0,04616872 0,05844142 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,04616872 0,05840927 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,04616872 0,05837716 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,04616872 0,05834509 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 0,000 0,04616872 0,05831305 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,04616872 0,05828104 ! female gonad development GO:0008585 49 33 0,000 0,04616872 0,05824907 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,04616872 0,05821714 ! positive regulation of cell development GO:0010720 54 33 0,000 0,04616872 0,05818524 ! lipid homeostasis GO:0055088 55 33 0,000 0,04616872 0,05815337 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,04616872 0,05812154 ! regulation of proteolysis GO:0030162 50 33 0,000 0,04616872 0,05808975 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,04616872 0,05805799 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,04616872 0,05802626 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,04616872 0,05799457 ! cytokinesis GO:0000910 52 33 0,000 0,04616872 0,05796291 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,04616872 0,05793129 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,04753532 0,05961354 ! mRNA catabolic process GO:0006402 48 34 0,000 0,04753532 0,05958105 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,04753532 0,0595486 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,04753532 0,05951619 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,04753532 0,0594838 ! feeding behavior GO:0007631 45 34 0,000 0,04753532 0,05945146 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,04753532 0,05941915 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,04753532 0,05938687 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,04753532 0,05935463 ! neuron migration GO:0001764 46 34 0,000 0,04753532 0,05932243 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,04753532 0,05929026 ! female gamete generation GO:0007292 43 34 0,000 0,04753532 0,05925812 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,04753532 0,05922602 ! polyol metabolic process GO:0019751 44 34 0,000 0,04753532 0,05919395 ! aerobic respiration GO:0009060 47 34 0,000 0,04753532 0,05916192 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,04753532 0,05912993 ! embryonic organ development GO:0048568 45 34 0,000 0,04753532 0,05909796 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,04753532 0,05906604 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,04890004 0,06072899 ! Notch signaling pathway GO:0007219 56 35 0,000 0,04890004 0,06069622 ! regulation of intracellular protein transport GO:0033157 59 35 0,000 0,04890004 0,06066348 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,04890004 0,06063077 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,04890004 0,06059811 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,04890004 0,06056547 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,04890004 0,06053288 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,04890004 0,06050032 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,04890004 0,06046779 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,04890004 0,0604353 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,04890004 0,06040284 ! glycogen metabolic process GO:0005977 48 35 0,000 0,04890004 0,06037042 ! pigment metabolic process GO:0042440 61 35 0,000 0,04890004 0,06033803 ! positive regulation of leukocyte proliferation GO:0070665 50 35 0,000 0,04890004 0,06030568 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! protein homooligomerization GO:0051260 52 35 0,000 0,04890004 0,06027336 ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,05026288 0,06191999 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 0,000 0,05026288 0,06188684 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,05026288 0,06185373 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,05026288 0,06182065 ! negative regulation of binding GO:0051100 58 36 0,000 0,05026288 0,06178761 ! organic ether metabolic process GO:0018904 46 36 0,000 0,05026288 0,06175461 ! tissue remodeling GO:0048771 62 36 0,000 0,05026288 0,06172164 ! neural tube development GO:0021915 50 36 0,000 0,05026288 0,0616887 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,05026288 0,0616558 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,05026288 0,06162293 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,05026288 0,0615901 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,05026288 0,06155731 ! glucan metabolic process GO:0044042 49 36 0,000 0,05026288 0,06152455 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,05162385 0,06315683 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,05162385 0,06312326 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,05162385 0,06308972 ! learning GO:0007612 67 37 0,000 0,05162385 0,06305621 ! ion transmembrane transport GO:0034220 56 37 0,000 0,05162385 0,06302274 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,05162385 0,06298931 ! regulation of protein secretion GO:0050708 51 37 0,000 0,05162385 0,06295591 ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,05162385 0,06292255 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,05298294 0,0645449 ! gliogenesis GO:0042063 71 38 0,000 0,05298294 0,06451073 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,05298294 0,06447659 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,05298294 0,0644425 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,05298294 0,06440844 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,05298294 0,06437441 ! phagocytosis GO:0006909 60 38 0,000 0,05298294 0,06434042 ! mesenchymal cell development GO:0014031 64 38 0,000 0,05298294 0,06430647 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 0,000 0,05298294 0,06427255 ! maintenance of location in cell GO:0051651 69 38 0,000 0,05298294 0,06423867 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,05434017 0,06584952 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,05434017 0,06581484 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,05434017 0,0657802 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,05434017 0,0657456 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,05434017 0,06571103 ! regulation of epithelial cell proliferation GO:0050678 71 39 0,000 0,05434017 0,0656765 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,05434017 0,06564201 ! male sex differentiation GO:0046661 53 39 0,000 0,05434017 0,06560755 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,05434017 0,06557313 ! chromatin remodeling GO:0006338 68 39 0,000 0,05434017 0,06553874 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,05434017 0,06550439 ! JNK cascade GO:0007254 54 39 0,000 0,05434017 0,06547008 ! developmental growth GO:0048589 62 39 0,000 0,05434017 0,0654358 ! cell growth GO:0016049 61 39 0,000 0,05434017 0,06540156 ! synapse organization GO:0050808 55 39 0,000 0,05434017 0,06536735 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,05569552 0,06696273 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,05569552 0,06692774 ! regulation of tube size GO:0035150 60 40 0,000 0,05569552 0,06689279 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,05569552 0,06685788 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,05569552 0,06682301 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,05569552 0,06678817 ! peptide metabolic process GO:0006518 56 40 0,000 0,05569552 0,06675336 ! induction of apoptosis by intracellular signals GO:0008629 67 40 0,000 0,05569552 0,06671859 ! inner ear development GO:0048839 57 40 0,000 0,05569552 0,06668386 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,05569552 0,06664917 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,05569552 0,06661451 ! B cell differentiation GO:0030183 62 40 0,000 0,05569552 0,06657989 ! epidermal cell differentiation GO:0009913 53 40 0,000 0,05569552 0,0665453 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,05569552 0,06651075 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,05569552 0,06647623 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,05569552 0,06644175 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,05704901 0,06802112 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,05704901 0,06798587 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,05704901 0,06795066 ! glucose transport GO:0015758 52 41 0,000 0,05704901 0,06791549 ! endosome transport GO:0016197 71 41 0,000 0,05704901 0,06788036 ! striated muscle contraction GO:0006941 62 41 0,000 0,05704901 0,06784526 ! positive regulation of DNA binding GO:0043388 57 41 0,000 0,05704901 0,0678102 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,05704901 0,06777517 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,05704901 0,06774018 ! biopolymer methylation GO:0043414 62 41 0,000 0,05704901 0,06770523 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,05704901 0,06767031 ! mitochondrial transport GO:0006839 60 42 0,000 0,05840064 0,06923788 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 0,000 0,05840064 0,06920221 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,05840064 0,06916657 ! cellular component disassembly GO:0022411 64 42 0,000 0,05840064 0,06913097 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,05840064 0,06909541 ! hexose transport GO:0008645 54 42 0,000 0,05840064 0,06905989 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,05840064 0,0690244 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,05840064 0,06898895 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,05840064 0,06895353 ! excretion GO:0007588 63 42 0,000 0,05840064 0,06891815 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,05840064 0,06888281 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,05840064 0,06884751 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,05840064 0,06881223 ! regulation of cell shape GO:0008360 78 42 0,000 0,05840064 0,068777 ! positive regulation of binding GO:0051099 59 43 0,000 0,05975041 0,07033058 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,05975041 0,07029461 ! leukocyte migration GO:0050900 60 43 0,000 0,05975041 0,07025867 ! neuromuscular process GO:0050905 79 43 0,000 0,05975041 0,07022277 ! activation of caspase activity GO:0006919 65 43 0,000 0,05975041 0,0701869 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,05975041 0,07015107 ! tRNA processing GO:0008033 49 43 0,000 0,05975041 0,07011528 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,05975041 0,07007953 ! vesicle organization GO:0016050 79 43 0,000 0,05975041 0,07004381 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,05975041 0,07000813 ! methylation GO:0032259 64 43 0,000 0,05975041 0,06997248 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,06109833 0,07151458 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,06109833 0,0714782 ! glycolysis GO:0006096 53 44 0,000 0,06109833 0,07144187 ! regulation of action potential GO:0001508 71 44 0,000 0,06109833 0,07140556 ! regulation of ion transport GO:0043269 57 44 0,000 0,06109833 0,0713693 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,06109833 0,07133307 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,06109833 0,07129688 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,06109833 0,07126073 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,06109833 0,07122461 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,06109833 0,07118853 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,06109833 0,07115248 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,06109833 0,07111647 ! regulation of mast cell proliferation GO:0070666 64 44 0,000 0,06109833 0,0710805 ! RNA catabolic process GO:0006401 64 45 0,000 0,06244438 0,07260975 ! positive regulation of defense response GO:0031349 59 45 0,000 0,06244438 0,07257306 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,06244438 0,0725364 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,06244438 0,07249979 ! cell recognition GO:0008037 58 45 0,000 0,06244438 0,07246321 ! cell maturation GO:0048469 60 45 0,000 0,06244438 0,07242667 ! protein amino acid autophosphorylation GO:0046777 80 45 0,000 0,06244438 0,07239016 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,06378859 0,07391121 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,06378859 0,07387399 ! cell redox homeostasis GO:0045454 63 46 0,000 0,06378859 0,07383682 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,06378859 0,07379967 ! regulation of ossification GO:0030278 71 46 0,000 0,06378859 0,07376257 ! histone modification GO:0016570 68 46 0,000 0,06378859 0,0737255 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,06378859 0,07368847 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,06513094 0,07520139 ! viral infectious cycle GO:0019058 71 47 0,000 0,06513094 0,07516366 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,06513094 0,07512596 ! endocrine system development GO:0035270 83 47 0,000 0,06513094 0,0750883 ! covalent chromatin modification GO:0016569 75 47 0,000 0,06513094 0,07505068 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,06513094 0,0750131 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,06513094 0,07497556 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,06513094 0,07493805 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,06513094 0,07490058 ! regulation of leukocyte proliferation GO:0070663 71 47 0,000 0,06513094 0,07486315 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,06513094 0,07482576 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,06513094 0,0747884 ! chloride transport GO:0006821 67 48 0,000 0,06647145 0,07628959 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,06647145 0,07625154 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 0,000 0,06647145 0,07621352 ! response to temperature stimulus GO:0009266 62 48 0,000 0,06647145 0,07617555 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,06647145 0,07613761 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,06647145 0,07609972 ! gastrulation GO:0007369 73 48 0,000 0,06647145 0,07606186 ! heart morphogenesis GO:0003007 65 48 0,000 0,06647145 0,07602403 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,06647145 0,07598625 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,06647145 0,0759485 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,06647145 0,07591079 ! regulation of endocytosis GO:0030100 63 48 0,000 0,06647145 0,07587312 ! nuclear export GO:0051168 69 48 0,000 0,06647145 0,07583548 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,06647145 0,07579788 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,06647145 0,07576032 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,06781011 0,07724777 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,06781011 0,07720953 ! sensory perception of smell GO:0007608 61 49 0,000 0,06781011 0,07717133 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,06781011 0,07713316 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,06781011 0,07709503 ! RNA elongation GO:0006354 62 49 0,000 0,06781011 0,07705694 ! regulation of intracellular transport GO:0032386 78 49 0,000 0,06781011 0,07701889 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,06781011 0,07698087 ! germ cell development GO:0007281 68 49 0,000 0,06781011 0,0769429 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,06781011 0,07690496 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,06781011 0,07686705 ! cartilage development GO:0051216 70 49 0,000 0,06781011 0,07682919 ! maintenance of location GO:0051235 84 49 0,000 0,06781011 0,07679136 ! regulation of actin filament length GO:0030832 72 50 0,000 0,06914693 0,0782667 ! ear development GO:0043583 72 50 0,000 0,06914693 0,0782282 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,06914693 0,07818974 ! membrane fusion GO:0006944 80 50 0,000 0,06914693 0,07815132 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,06914693 0,07811293 ! lipid modification GO:0030258 73 50 0,000 0,06914693 0,07807459 ! positive regulation of growth GO:0045927 67 50 0,000 0,06914693 0,07803628 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,06914693 0,077998 ! proton transport GO:0015992 75 50 0,000 0,06914693 0,07795977 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,06914693 0,07792157 ! positive regulation of secretion GO:0051047 71 51 0,000 0,0704819 0,07938706 ! hydrogen transport GO:0006818 77 51 0,000 0,0704819 0,0793482 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,0704819 0,07930938 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 0,000 0,0704819 0,0792706 ! positive regulation of cell migration GO:0030335 92 51 0,000 0,0704819 0,07923186 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,0704819 0,07919315 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,0704819 0,07915448 ! adult behavior GO:0030534 80 51 0,000 0,0704819 0,07911585 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,0704819 0,07907726 ! transition metal ion transport GO:0000041 74 52 0,000 0,07181504 0,08053369 ! regulation of cellular component size GO:0032535 74 52 0,000 0,07181504 0,08049444 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,07181504 0,08045524 ! aging GO:0007568 79 52 0,000 0,07181504 0,08041607 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,07181504 0,08037693 ! establishment of organelle localization GO:0051656 85 52 0,000 0,07181504 0,08033784 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,07314635 0,08178736 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,07314635 0,08174762 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,07314635 0,08170792 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,07314635 0,08166825 ! kidney development GO:0001822 90 53 0,000 0,07314635 0,08162863 ! single fertilization GO:0007338 59 53 0,000 0,07314635 0,08158904 ! cell projection assembly GO:0030031 76 53 0,000 0,07314635 0,08154949 ! amino acid transport GO:0006865 84 54 0,000 0,07447582 0,08299146 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,07447582 0,08295127 ! regulation of mitosis GO:0007088 84 54 0,000 0,07447582 0,08291112 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,07447582 0,08287101 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,07447582 0,08283094 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,07447582 0,0827909 ! DNA catabolic process GO:0006308 67 54 0,000 0,07447582 0,08275091 ! detection of external stimulus GO:0009581 66 54 0,000 0,07447582 0,08271095 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,07447582 0,08267103 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,07447582 0,08263115 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,07447582 0,08259131 ! exocytosis GO:0006887 74 55 0,000 0,07580346 0,08402311 ! mesoderm development GO:0007498 76 55 0,000 0,07580346 0,08398264 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,07580346 0,0839422 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,07580346 0,08390181 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,07712927 0,0853282 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,07712927 0,08528717 ! positive regulation of cell motion GO:0051272 99 56 0,000 0,07712927 0,08524619 ! negative regulation of protein kinase activity GO:0006469 99 57 0,000 0,07845325 0,08666786 ! carbohydrate transport GO:0008643 74 57 0,000 0,07845325 0,08662625 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,07845325 0,08658469 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 0,000 0,07845325 0,08654316 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,07845325 0,08650167 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,07845325 0,08646022 ! camera-type eye development GO:0043010 88 57 0,000 0,07845325 0,08641881 ! secondary metabolic process GO:0019748 84 57 0,000 0,07845325 0,08637745 ! developmental maturation GO:0021700 75 57 0,000 0,07845325 0,08633612 ! gonad development GO:0008406 79 57 0,000 0,07845325 0,08629483 ! negative regulation of kinase activity GO:0033673 100 58 0,000 0,07977542 0,0877072 ! viral reproductive process GO:0022415 87 58 0,000 0,07977542 0,08766529 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,07977542 0,08762343 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,07977542 0,0875816 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,07977542 0,08753982 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,08109576 0,08894623 ! activation of MAPK activity GO:0000187 84 59 0,000 0,08109576 0,08890383 ! lung development GO:0030324 94 59 0,000 0,08109576 0,08886148 ! actin filament organization GO:0007015 95 59 0,000 0,08109576 0,08881916 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,08109576 0,08877689 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,08109576 0,08873465 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,08241428 0,09013449 ! phosphoinositide metabolic process GO:0030384 87 60 0,000 0,08241428 0,09009165 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,08241428 0,09004886 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,08241428 0,0900061 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,08241428 0,08996338 ! regulation of heart contraction GO:0008016 91 60 0,000 0,08241428 0,0899207 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,08241428 0,08987807 ! fertilization GO:0009566 68 60 0,000 0,08241428 0,08983547 ! regulation of homeostatic process GO:0032844 105 60 0,000 0,08241428 0,08979291 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,08373098 0,09118431 ! meiosis GO:0007126 96 61 0,000 0,08373098 0,09114116 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 114 61 0,000 0,08373098 0,09109804 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,08373098 0,09105497 ! urogenital system development GO:0001655 101 61 0,000 0,08373098 0,09101194 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,08373098 0,09096895 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,08373098 0,090926 ! extracellular matrix organization GO:0030198 103 61 0,000 0,08373098 0,09088309 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,08373098 0,09084022 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! negative regulation of transferase activity GO:0051348 105 61 0,000 0,08373098 0,09079739 ! amine catabolic process GO:0009310 90 62 0,000 0,08504588 0,09217979 ! neurotransmitter transport GO:0006836 81 62 0,000 0,08504588 0,09213637 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,08504588 0,09209299 ! negative regulation of cell growth GO:0030308 106 62 0,000 0,08504588 0,09204965 ! respiratory tube development GO:0030323 99 62 0,000 0,08504588 0,09200636 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,08504588 0,0919631 ! meiotic cell cycle GO:0051321 97 62 0,000 0,08504588 0,09191988 ! organelle localization GO:0051640 96 62 0,000 0,08504588 0,09187671 ! regulation of transcription factor activity GO:0051090 97 63 0,000 0,08635896 0,09325145 GO:0090046|regulation of transcription regulator activity, ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,08635896 0,09320769 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 0,000 0,08635896 0,09316398 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 0,000 0,08635896 0,0931203 ! viral reproduction GO:0016032 92 63 0,000 0,08635896 0,09307666 ! regulation of lipase activity GO:0060191 109 63 0,000 0,08635896 0,09303307 ! negative regulation of cell size GO:0045792 108 64 0,000 0,08767023 0,09440146 ! appendage morphogenesis GO:0035107 93 64 0,000 0,08767023 0,09435729 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,08767023 0,09431315 ! hexose catabolic process GO:0019320 82 64 0,000 0,08767023 0,09426906 ! respiratory system development GO:0060541 100 64 0,000 0,08767023 0,09422501 ! adaptive immune response GO:0002250 94 64 0,000 0,08767023 0,094181 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 90 65 0,000 0,08897969 0,09554308 ! regulation of caspase activity GO:0043281 97 65 0,000 0,08897969 0,0954985 ! appendage development GO:0048736 94 65 0,000 0,08897969 0,09545396 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 0,000 0,08897969 0,09540946 ! defense response to bacterium GO:0042742 73 65 0,000 0,08897969 0,095365 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,08897969 0,09532058 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,08897969 0,0952762 ! activation of immune response GO:0002253 83 65 0,000 0,08897969 0,09523187 ! protein oligomerization GO:0051259 100 65 0,000 0,08897969 0,09518758 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,09028735 0,09654156 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,09028735 0,0964967 ! antigen processing and presentation GO:0019882 96 66 0,000 0,09028735 0,09645188 ! axon guidance GO:0007411 99 66 0,000 0,09028735 0,09640711 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,09028735 0,09636237 ! regulation of immune effector process GO:0002697 101 66 0,000 0,09028735 0,09631767 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,09159321 0,09766545 ! regulation of endopeptidase activity GO:0052548 99 67 0,000 0,09159321 0,09762019 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,09159321 0,09757498 ! acute inflammatory response GO:0002526 92 68 0,000 0,09289727 0,09891838 ! learning or memory GO:0007611 123 68 0,000 0,09289727 0,09887261 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,09289727 0,09882688 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,09289727 0,09878119 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,09289727 0,09873554 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,09289727 0,09868994 ! rhythmic process GO:0048511 105 68 0,000 0,09289727 0,09864437 ! inorganic anion transport GO:0015698 93 68 0,000 0,09289727 0,09859885 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,09419953 0,09993492 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,09419953 0,09988885 ! response to drug GO:0042493 108 69 0,000 0,09419953 0,09984282 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,09549999 0,10117457 ! humoral immune response GO:0006959 86 70 0,000 0,09549999 0,10112798 ! eye development GO:0001654 111 70 0,000 0,09549999 0,10108145 ! amine transport GO:0015837 101 70 0,000 0,09549999 0,10103495 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,09549999 0,1009885 ! regulation of catabolic process GO:0009894 106 70 0,000 0,09549999 0,10094209 ! muscle cell differentiation GO:0042692 104 71 0,000 0,09679867 0,10226777 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,09679867 0,10222081 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,09679867 0,1021739 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,09679867 0,10212703 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,09679867 0,10208021 ! regulation of peptidase activity GO:0052547 106 72 0,000 0,09809555 0,10340044 ! response to hypoxia GO:0001666 132 72 0,000 0,09809555 0,10335307 ! negative regulation of organelle organization GO:0010639 115 72 0,000 0,09809555 0,10330575 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,09809555 0,10325847 ! negative regulation of transport GO:0051051 116 73 0,000 0,09939064 0,10457387 ! regulation of blood pressure GO:0008217 107 73 0,000 0,09939064 0,10452605 ! tube morphogenesis GO:0035239 118 73 0,000 0,09939064 0,10447828 ! mitochondrion organization GO:0007005 104 73 0,000 0,09939064 0,10443055 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,09939064 0,10438287 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,09939064 0,10433523 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,10068395 0,10564466 ! response to oxygen levels GO:0070482 137 74 0,000 0,10068395 0,10559649 ! digestion GO:0007586 97 74 0,000 0,10068395 0,10554836 ! positive regulation of lymphocyte activation GO:0051251 108 74 0,000 0,10068395 0,10550027 ! blood coagulation GO:0007596 116 75 0,000 0,10197548 0,10680492 GO:0050817|coagulation, ! negative regulation of growth GO:0045926 123 75 0,000 0,10197548 0,10675631 ! response to nutrient GO:0007584 104 75 0,000 0,10197548 0,10670774 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,10197548 0,10665921 ! amine biosynthetic process GO:0009309 97 76 0,000 0,10326523 0,1079591 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,10326523 0,10791005 ! regulation of protein transport GO:0051223 114 76 0,000 0,10326523 0,10786105 GO:0070201|regulation of establishment of protein localization, ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,1045532 0,10915676 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,1045532 0,10910724 ! regulation of DNA binding GO:0051101 119 77 0,000 0,1045532 0,10905775 ! gland development GO:0048732 148 77 0,000 0,1045532 0,10900832 ! sex differentiation GO:0007548 105 77 0,000 0,1045532 0,10895893 ! protein ubiquitination GO:0016567 125 77 0,000 0,1045532 0,10890958 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,1045532 0,10886028 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,1045532 0,10881102 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,1045532 0,1087618 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,10583939 0,11005 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,10583939 0,11000027 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,10712381 0,11128489 ! cellular respiration GO:0045333 107 79 0,000 0,10712381 0,11123465 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,10712381 0,11118445 ! T cell activation GO:0042110 134 79 0,000 0,10712381 0,1111343 ! regulation of lyase activity GO:0051339 133 79 0,000 0,10712381 0,1110842 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,10712381 0,11103414 ! chromatin assembly GO:0031497 102 80 0,000 0,10840645 0,11231299 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,10840645 0,11226242 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,10840645 0,1122119 ! forebrain development GO:0030900 131 80 0,000 0,10840645 0,11216142 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,10968733 0,11343564 ! hemostasis GO:0007599 125 81 0,000 0,10968733 0,11338466 ! mRNA transport GO:0051028 121 81 0,000 0,10968733 0,11333372 ! regulation of cell cycle process GO:0010564 122 81 0,000 0,10968733 0,11328283 ! regulation of neurological system process GO:0031644 122 81 0,000 0,10968733 0,11323198 ! vitamin metabolic process GO:0006766 103 81 0,000 0,10968733 0,11318118 ! positive regulation of cell activation GO:0050867 120 81 0,000 0,10968733 0,11313043 GO:0002696|positive regulation of leukocyte activation, ! ossification GO:0001503 134 82 0,000 0,11096644 0,11439839 GO:0060348|bone development, ! detection of stimulus GO:0051606 108 82 0,000 0,11096644 0,11434714 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,11224379 0,1156116 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,11224379 0,11555985 ! regulation of cell adhesion GO:0030155 159 83 0,000 0,11224379 0,11550815 ! regulation of defense response GO:0031347 117 84 0,000 0,11351937 0,11676859 ! microtubule cytoskeleton organization GO:0000226 120 84 0,000 0,11351937 0,11671639 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,11351937 0,11666424 ! sterol metabolic process GO:0016125 120 84 0,000 0,11351937 0,11661213 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,1147932 0,11786802 ! rRNA metabolic process GO:0016072 107 85 0,000 0,1147932 0,11781542 GO:0006364|rRNA processing, ! positive regulation of MAP kinase activity GO:0043406 121 85 0,000 0,1147932 0,11776287 ! transcription initiation GO:0006352 118 85 0,000 0,1147932 0,11771037 ! anterior/posterior pattern formation GO:0009952 124 85 0,000 0,1147932 0,11765791 ! regulation of protein localization GO:0032880 132 85 0,000 0,1147932 0,1176055 ! regulation of membrane potential GO:0042391 128 85 0,000 0,1147932 0,11755314 ! negative regulation of multicellular organismal process GO:0051241 133 85 0,000 0,1147932 0,11750083 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,11606527 0,11875005 ! cell cycle arrest GO:0007050 150 86 0,000 0,11606527 0,11869725 ! nucleosome organization GO:0034728 114 87 0,000 0,11733558 0,11994304 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,11733558 0,11988975 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,11733558 0,11983652 ! skeletal muscle tissue development GO:0007519 123 87 0,000 0,11733558 0,11978333 GO:0060538|skeletal muscle organ development, ! female pregnancy GO:0007565 130 87 0,000 0,11733558 0,11973018 ! Wnt receptor signaling pathway GO:0016055 130 87 0,000 0,11733558 0,11967709 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,11860414 0,12091734 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,11860414 0,12086377 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,11860414 0,12081024 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,11860414 0,12075676 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 0,000 0,11860414 0,12070333 ! regulation of neurogenesis GO:0050767 153 89 0,000 0,11987095 0,12193861 ! reproductive developmental process GO:0003006 127 89 0,000 0,11987095 0,1218847 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,11987095 0,12183084 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,11987095 0,12177703 ! regulation of T cell activation GO:0050863 128 89 0,000 0,11987095 0,12172326 ! leukocyte differentiation GO:0002521 143 90 0,000 0,12113601 0,12295359 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,12113601 0,12289935 ! hormone metabolic process GO:0042445 121 90 0,000 0,12113601 0,12284516 ! RNA localization GO:0006403 135 91 0,000 0,12239933 0,1240716 ! ATP metabolic process GO:0046034 137 91 0,000 0,12239933 0,12401694 ! response to virus GO:0009615 122 91 0,000 0,12239933 0,12396233 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,1236609 0,12518489 ! glycerophospholipid metabolic process GO:0006650 130 92 0,000 0,1236609 0,12512982 ! cell fate commitment GO:0045165 141 92 0,000 0,1236609 0,12507479 ! positive regulation of immune response GO:0050778 121 92 0,000 0,1236609 0,12501981 ! sulfur metabolic process GO:0006790 118 92 0,000 0,1236609 0,12496488 ! regulation of cytoskeleton organization GO:0051493 154 93 0,000 0,12492073 0,12618256 ! peptidyl-amino acid modification GO:0018193 147 93 0,000 0,12492073 0,12612717 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,12492073 0,12607183 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,12492073 0,12601653 ! electron transport chain GO:0022900 123 94 0,000 0,12617883 0,12722986 ! response to oxidative stress GO:0006979 141 94 0,000 0,12617883 0,1271741 ! regulation of binding GO:0051098 151 95 0,000 0,12743518 0,12838411 ! angiogenesis GO:0001525 149 95 0,000 0,12743518 0,1283279 ! carboxylic acid transport GO:0046942 147 95 0,000 0,12743518 0,12827174 GO:0015849|organic acid transport, ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,12868981 0,12947793 ! in utero embryonic development GO:0001701 147 96 0,000 0,12868981 0,12942132 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,12868981 0,12936475 ! regulation of cellular component biogenesis GO:0044087 158 96 0,000 0,12868981 0,12930824 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,12868981 0,12925177 ! protein maturation GO:0051604 129 96 0,000 0,12868981 0,12919535 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,1299427 0,13039625 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,1299427 0,13033938 ! calcium ion transport GO:0006816 167 99 0,000 0,13244329 0,1327897 ! extracellular structure organization GO:0043062 156 99 0,000 0,13244329 0,13273184 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 0,000 0,13244329 0,13267403 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,133691 0,13386561 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,133691 0,13380735 ! divalent metal ion transport GO:0070838 171 100 0,000 0,133691 0,13374915 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,133691 0,133691