pValThreshold = 0.5 scoreFile = /home/data/iti/output/run-b1/out-0.05-06-0.01-300-run-b1//th1-pval-1e-01-08-th2-pval-1e-02-02-th3-pval-1e-01-01-run-b1/go_data/1164-1-real-Ivshina_GPL96-GPL97-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 2,000 2,878E-06 6,924E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 6,472E-06 7,785E-03 ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 2,767E-05 0,022193 GO:0031114|regulation of microtubule depolymerization, ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 3,135E-05 0,01885862 ! cellular response to unfolded protein GO:0034620 33 19 1,000 3,94E-05 0,01895864 GO:0030968|endoplasmic reticulum unfolded protein response, ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 5,318E-05 0,02132391 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 6,9E-05 0,02371671 ! fat cell differentiation GO:0045444 50 27 1,000 8,068E-05 0,02426601 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 8,687E-05 0,02322232 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 9,327E-05 0,02244178 ! spindle organization GO:0007051 46 32 1,000 1,139E-04 0,02490264 ! regulation of microtubule-based process GO:0032886 78 35 1,000 1,365E-04 0,02736008 ! meiosis I GO:0007127 65 37 1,000 1,527E-04 0,02825287 ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 1,971E-04 0,03386742 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 1,000 2,366E-04 0,03795389 ! response to calcium ion GO:0051592 81 47 1,000 2,471E-04 0,03715249 ! positive regulation of cell cycle GO:0045787 89 48 1,000 2,577E-04 0,03647686 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 2,686E-04 0,03590601 ! response to UV GO:0009411 104 53 1,000 3,144E-04 0,0398133 ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 3,264E-04 0,03926606 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 5,175E-04 0,05929161 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 5,328E-04 0,05826922 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 1,000 5,8E-04 0,06067254 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 5,8E-04 0,05814452 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 1,000 5,8E-04 0,05581874 ! meiosis GO:0007126 121 74 1,000 6,125E-04 0,05668402 GO:0051327|M phase of meiotic cell cycle, ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 6,291E-04 0,05606395 ! meiotic cell cycle GO:0051321 122 75 1,000 6,291E-04 0,05406167 ! positive regulation of ligase activity GO:0051351 124 77 1,000 6,63E-04 0,05500612 ! negative regulation of organelle organization GO:0010639 161 78 1,000 6,803E-04 0,05455617 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 1,000 6,977E-04 0,05415205 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 6,977E-04 0,0524598 ! response to metal ion GO:0010038 140 80 1,000 7,154E-04 0,05215947 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 7,333E-04 0,05189209 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of ligase activity GO:0051340 142 84 1,000 7,883E-04 0,05419008 ! response to unfolded protein GO:0006986 131 85 1,000 8,071E-04 0,0539388 ! response to inorganic substance GO:0010035 153 86 1,000 8,26E-04 0,05371509 ! positive regulation of protein modification process GO:0031401 136 88 1,000 8,646E-04 0,0547456 ! response to protein stimulus GO:0051789 149 91 1,000 9,242E-04 0,05701322 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 9,649E-04 0,05803865 GO:0010498|proteasomal protein catabolic process, ! interphase of mitotic cell cycle GO:0051329 209 95 1,000 1,006E-03 0,05906421 ! interphase GO:0051325 213 98 1,000 1,07E-03 0,06132403 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 2,488E-03 0,1392108 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 2,488E-03 0,13604692 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 2,488E-03 0,13302365 ! positive regulation of helicase activity GO:0051096 11 5 0,000 2,488E-03 0,13013183 ! neuron fate determination GO:0048664 7 5 0,000 2,488E-03 0,12736307 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 2,488E-03 0,12470967 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 2,488E-03 0,12216458 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 2,488E-03 0,11972129 ! polyol transport GO:0015791 12 5 0,000 2,488E-03 0,11737381 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 2,488E-03 0,11511662 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 2,488E-03 0,11294461 ! response to superoxide GO:0000303 10 5 0,000 2,488E-03 0,11085304 ! negative regulation of bone resorption GO:0045779 10 5 0,000 2,488E-03 0,10883753 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 2,488E-03 0,10689401 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 2,488E-03 0,10501867 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 2,488E-03 0,10320801 ! female meiosis GO:0007143 7 5 0,000 2,488E-03 0,10145872 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 2,488E-03 0,09976774 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 2,488E-03 0,0981322 ! cobalt ion transport GO:0006824 11 5 0,000 2,488E-03 0,09654943 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 2,488E-03 0,0950169 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 2,488E-03 0,09353226 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 2,488E-03 0,0920933 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 2,488E-03 0,09069795 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 2,488E-03 0,08934424 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 2,488E-03 0,08803036 ! embryonic camera-type eye development GO:0031076 10 5 0,000 2,488E-03 0,08675456 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 2,488E-03 0,08551521 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 2,488E-03 0,08431077 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 2,488E-03 0,08313978 ! adaptation of signaling pathway GO:0022401 7 5 0,000 2,488E-03 0,08200088 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 2,488E-03 0,08089276 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 2,488E-03 0,07981419 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 2,488E-03 0,07876401 ! negative chemotaxis GO:0050919 14 5 0,000 2,488E-03 0,0777411 ! positive regulation of histone modification GO:0031058 5 5 0,000 2,488E-03 0,07674442 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 2,488E-03 0,07577297 ! sensory perception of bitter taste GO:0050913 7 5 0,000 2,488E-03 0,0748258 ! behavioral response to pain GO:0048266 9 5 0,000 2,488E-03 0,07390203 ! clathrin coat assembly GO:0048268 14 5 0,000 2,488E-03 0,07300079 ! Notch receptor processing GO:0007220 8 5 0,000 2,488E-03 0,07212126 ! regulation of dopamine uptake GO:0051584 9 5 0,000 2,488E-03 0,07126267 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 2,488E-03 0,07042429 ! micturition GO:0060073 9 5 0,000 2,488E-03 0,0696054 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 2,488E-03 0,06880534 ! copulation GO:0007620 9 5 0,000 2,488E-03 0,06802346 ! glial cell fate commitment GO:0021781 13 5 0,000 2,488E-03 0,06725915 ! protein maturation by protein folding GO:0022417 13 5 0,000 2,488E-03 0,06651183 ! spermidine metabolic process GO:0008216 7 5 0,000 2,488E-03 0,06578093 ! regulation of potassium ion transport GO:0043266 10 5 0,000 2,488E-03 0,06506592 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 2,488E-03 0,06436628 ! apoptotic cell clearance GO:0043277 20 5 0,000 2,488E-03 0,06368154 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 2,488E-03 0,0630112 ! lipoprotein particle clearance GO:0034381 10 5 0,000 2,488E-03 0,06235484 ! grooming behavior GO:0007625 6 5 0,000 2,488E-03 0,061712 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 2,488E-03 0,06108229 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 2,488E-03 0,0604653 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 2,488E-03 0,05986064 ! response to protozoan GO:0001562 10 5 0,000 2,488E-03 0,05926796 ! positive regulation of glycolysis GO:0045821 14 5 0,000 2,488E-03 0,05868691 ! lymph vessel development GO:0001945 10 5 0,000 2,488E-03 0,05811713 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 2,488E-03 0,05755831 ! endochondral ossification GO:0001958 16 5 0,000 2,488E-03 0,05701014 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 2,488E-03 0,05647231 ! parathyroid gland development GO:0060017 13 5 0,000 2,488E-03 0,05594453 ! anagen GO:0042640 6 5 0,000 2,488E-03 0,05542652 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 2,488E-03 0,05491802 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 2,488E-03 0,05441877 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 2,488E-03 0,05392851 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 2,488E-03 0,053447 ! dorsal spinal cord development GO:0021516 7 5 0,000 2,488E-03 0,05297402 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 2,488E-03 0,05250934 ! sphingoid catabolic process GO:0046521 6 5 0,000 2,488E-03 0,05205273 ! skeletal myofibril assembly GO:0014866 10 5 0,000 2,488E-03 0,051604 ! smooth muscle tissue development GO:0048745 28 5 0,000 2,488E-03 0,05116294 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 2,488E-03 0,05072936 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 2,488E-03 0,05030306 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 2,488E-03 0,04988387 ! cardiac muscle fiber development GO:0048739 10 5 0,000 2,488E-03 0,04947161 ! transepithelial chloride transport GO:0030321 9 5 0,000 2,488E-03 0,0490661 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 2,488E-03 0,04866719 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 2,488E-03 0,04827471 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 2,488E-03 0,04788852 ! neutrophil mediated immunity GO:0002446 7 5 0,000 2,488E-03 0,04750845 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 2,488E-03 0,04713437 ! histidine catabolic process GO:0006548 6 5 0,000 2,488E-03 0,04676613 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 2,488E-03 0,0464036 ! microvillus organization GO:0032528 7 5 0,000 2,488E-03 0,04604665 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 2,488E-03 0,04569515 ! L-serine biosynthetic process GO:0006564 6 5 0,000 2,488E-03 0,04534897 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 2,488E-03 0,045008 ! tryptophan metabolic process GO:0006568 9 5 0,000 2,488E-03 0,04467212 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 2,488E-03 0,04434122 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 2,488E-03 0,04401518 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 2,488E-03 0,0436939 ! polyol catabolic process GO:0046174 7 5 0,000 2,488E-03 0,04337728 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 2,488E-03 0,04306521 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 2,488E-03 0,0427576 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 2,488E-03 0,04245436 ! muscle cell migration GO:0014812 8 5 0,000 2,488E-03 0,04215538 ! mitochondrial fission GO:0000266 8 5 0,000 2,488E-03 0,04186059 ! sister chromatid cohesion GO:0007062 12 5 0,000 2,488E-03 0,04156989 ! mRNA transcription GO:0009299 9 5 0,000 2,488E-03 0,0412832 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 2,488E-03 0,04100044 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 2,488E-03 0,04072153 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 2,488E-03 0,04044638 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 2,488E-03 0,04017493 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 2,488E-03 0,0399071 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 2,488E-03 0,03964281 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 2,488E-03 0,039382 ! response to food GO:0032094 6 5 0,000 2,488E-03 0,0391246 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 2,488E-03 0,03887055 ! positive regulation of transporter activity GO:0032411 8 5 0,000 2,488E-03 0,03861977 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 2,488E-03 0,03837221 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 2,488E-03 0,0381278 ! paraxial mesoderm development GO:0048339 14 5 0,000 2,488E-03 0,03788648 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 2,488E-03 0,0376482 ! forebrain neuron development GO:0021884 13 5 0,000 2,488E-03 0,0374129 ! lipoprotein catabolic process GO:0042159 11 5 0,000 2,488E-03 0,03718052 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 2,488E-03 0,03695101 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 2,488E-03 0,03672432 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 2,488E-03 0,03650039 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 2,488E-03 0,03627918 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 2,488E-03 0,03606063 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 2,488E-03 0,0358447 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 2,488E-03 0,03563134 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 2,488E-03 0,0354205 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 2,488E-03 0,03521214 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 2,488E-03 0,03500622 ! basic amino acid transport GO:0015802 11 5 0,000 2,488E-03 0,0348027 ! cellular glucose homeostasis GO:0001678 5 5 0,000 2,488E-03 0,03460153 ! early endosome to late endosome transport GO:0045022 12 5 0,000 2,488E-03 0,03440267 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 2,488E-03 0,03420608 ! depyrimidination GO:0045008 10 5 0,000 2,488E-03 0,03401173 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 2,488E-03 0,03381957 ! regulation of centrosome cycle GO:0046605 7 5 0,000 2,488E-03 0,03362958 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 2,488E-03 0,0334417 ! zinc ion homeostasis GO:0055069 8 5 0,000 2,488E-03 0,03325591 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 2,488E-03 0,03307218 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 2,488E-03 0,03289046 ! forebrain morphogenesis GO:0048853 13 5 0,000 2,488E-03 0,03271073 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 2,488E-03 0,03253296 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 2,488E-03 0,0323571 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 2,488E-03 0,03218314 ! peptidyl-arginine modification GO:0018195 9 5 0,000 2,488E-03 0,03201104 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 2,488E-03 0,03184077 ! positive regulation of organ growth GO:0046622 6 5 0,000 2,488E-03 0,0316723 ! response to arsenic GO:0046685 10 5 0,000 2,488E-03 0,0315056 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 2,488E-03 0,03134065 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 2,488E-03 0,03117742 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 2,488E-03 0,03101588 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 2,488E-03 0,030856 ! response to cadmium ion GO:0046686 7 5 0,000 2,488E-03 0,03069777 ! bile acid biosynthetic process GO:0006699 6 5 0,000 2,488E-03 0,03054114 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 2,488E-03 0,03038611 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 2,488E-03 0,03023265 ! decidualization GO:0046697 11 5 0,000 2,488E-03 0,03008073 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 2,488E-03 0,02993032 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 2,488E-03 0,02978141 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 2,488E-03 0,02963398 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 2,488E-03 0,029488 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 2,488E-03 0,02934345 ! base conversion or substitution editing GO:0016553 5 5 0,000 2,488E-03 0,02920031 ! neural tube patterning GO:0021532 7 5 0,000 2,488E-03 0,02905856 ! embryonic cleavage GO:0040016 6 5 0,000 2,488E-03 0,02891819 ! peroxisome fission GO:0016559 5 5 0,000 2,488E-03 0,02877916 ! histone demethylation GO:0016577 10 5 0,000 2,488E-03 0,02864146 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 2,488E-03 0,02850507 ! mitotic recombination GO:0006312 9 5 0,000 2,488E-03 0,02836997 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 2,488E-03 0,02823615 ! metaphase plate congression GO:0051310 7 5 0,000 2,488E-03 0,02810359 ! regulation of sterol transport GO:0032371 7 5 0,000 2,488E-03 0,02797226 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 2,488E-03 0,02784216 ! enteric nervous system development GO:0048484 8 5 0,000 2,488E-03 0,02771326 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 2,488E-03 0,02758555 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 2,488E-03 0,02745901 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 2,488E-03 0,02733363 ! muscle cell proliferation GO:0033002 11 5 0,000 2,488E-03 0,02720938 ! skeletal muscle regeneration GO:0043403 8 5 0,000 2,488E-03 0,02708626 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 2,488E-03 0,02696425 ! plasminogen activation GO:0031639 5 5 0,000 2,488E-03 0,02684334 ! B cell homeostasis GO:0001782 13 5 0,000 2,488E-03 0,0267235 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 2,488E-03 0,02660473 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 2,488E-03 0,02648701 ! metaphase GO:0051323 8 5 0,000 2,488E-03 0,02637033 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 2,488E-03 0,02625467 ! cellular response to nutrient GO:0031670 8 5 0,000 2,488E-03 0,02614002 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 2,488E-03 0,02602637 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 2,488E-03 0,0259137 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 2,488E-03 0,025802 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 2,488E-03 0,02569126 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 2,488E-03 0,02558147 ! response to redox state GO:0051775 5 5 0,000 2,488E-03 0,02547261 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 2,488E-03 0,02536468 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 2,488E-03 0,02525766 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 2,488E-03 0,02515153 ! regulation of telomerase activity GO:0051972 6 5 0,000 2,488E-03 0,02504629 ! galactolipid metabolic process GO:0019374 7 5 0,000 2,488E-03 0,02494193 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 2,488E-03 0,02483844 ! porphyrin catabolic process GO:0006787 12 5 0,000 2,488E-03 0,0247358 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 2,488E-03 0,02463401 ! striatum development GO:0021756 9 5 0,000 2,488E-03 0,02453305 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 2,488E-03 0,02443292 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 2,488E-03 0,0243336 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 2,488E-03 0,02423508 ! glial cell migration GO:0008347 11 5 0,000 2,488E-03 0,02413736 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 2,488E-03 0,02404042 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 2,488E-03 0,02394426 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 2,488E-03 0,02384886 ! somatic stem cell maintenance GO:0035019 15 5 0,000 2,488E-03 0,02375422 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 2,488E-03 0,02366033 ! negative regulation of lipase activity GO:0060192 8 5 0,000 2,488E-03 0,02356718 ! neuroprotection GO:0043526 6 5 0,000 2,488E-03 0,02347476 ! neural plate development GO:0001840 8 5 0,000 2,488E-03 0,02338306 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 2,488E-03 0,02329208 ! regulation of sensory perception GO:0051931 7 5 0,000 2,488E-03 0,0232018 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 2,488E-03 0,02311222 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 2,488E-03 0,02302332 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 2,488E-03 0,02293511 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 2,488E-03 0,02284757 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 2,488E-03 0,0227607 ! sequestering of calcium ion GO:0051208 7 5 0,000 2,488E-03 0,02267449 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 2,488E-03 0,02258892 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 2,488E-03 0,022504 ! spindle assembly GO:0051225 6 5 0,000 2,488E-03 0,02241972 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 2,488E-03 0,02233606 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 2,488E-03 0,02225303 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 2,488E-03 0,02217061 ! drug metabolic process GO:0017144 6 5 0,000 2,488E-03 0,0220888 ! stem cell division GO:0017145 11 5 0,000 2,488E-03 0,02200759 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 2,488E-03 0,02192698 ! organ regeneration GO:0031100 7 5 0,000 2,488E-03 0,02184695 ! carnitine metabolic process GO:0009437 7 5 0,000 2,488E-03 0,02176751 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 2,488E-03 0,02168864 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 2,488E-03 0,02161034 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 2,985E-03 0,02583312 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 2,985E-03 0,02574053 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 2,985E-03 0,0256486 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 2,985E-03 0,02555732 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 2,985E-03 0,0254667 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 2,985E-03 0,02537671 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 2,985E-03 0,02528735 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 2,985E-03 0,02519862 ! sleep GO:0030431 13 6 0,000 2,985E-03 0,02511052 ! response to oxygen radical GO:0000305 11 6 0,000 2,985E-03 0,02502302 ! positive regulation of axon extension GO:0045773 11 6 0,000 2,985E-03 0,02493614 ! myoblast cell fate commitment GO:0048625 16 6 0,000 2,985E-03 0,02484985 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 2,985E-03 0,02476417 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 2,985E-03 0,02467907 ! regulation of interferon-beta production GO:0032648 8 6 0,000 2,985E-03 0,02459455 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 2,985E-03 0,02451061 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 2,985E-03 0,02442724 ! forebrain regionalization GO:0021871 8 6 0,000 2,985E-03 0,02434443 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 2,985E-03 0,02426219 ! male meiosis GO:0007140 7 6 0,000 2,985E-03 0,0241805 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 2,985E-03 0,02409936 ! response to zinc ion GO:0010043 9 6 0,000 2,985E-03 0,02401876 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 2,985E-03 0,02393869 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 2,985E-03 0,02385916 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 2,985E-03 0,02378016 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 2,985E-03 0,02370168 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 2,985E-03 0,02362371 ! malate metabolic process GO:0006108 11 6 0,000 2,985E-03 0,02354626 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 2,985E-03 0,02346931 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 2,985E-03 0,02339286 ! protein refolding GO:0042026 15 6 0,000 2,985E-03 0,02331691 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 2,985E-03 0,02324145 ! opsonization GO:0008228 8 6 0,000 2,985E-03 0,02316648 ! mating behavior GO:0007617 7 6 0,000 2,985E-03 0,02309199 ! neuron remodeling GO:0016322 15 6 0,000 2,985E-03 0,02301797 ! erythrocyte maturation GO:0043249 7 6 0,000 2,985E-03 0,02294443 ! embryonic hemopoiesis GO:0035162 14 6 0,000 2,985E-03 0,02287136 ! equilibrioception GO:0050957 14 6 0,000 2,985E-03 0,02279876 ! protein amino acid dealkylation GO:0008214 12 6 0,000 2,985E-03 0,02272661 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 2,985E-03 0,02265491 ! photoreceptor cell development GO:0042461 10 6 0,000 2,985E-03 0,02258367 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 2,985E-03 0,02251288 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 2,985E-03 0,02244252 ! response to interferon-gamma GO:0034341 15 6 0,000 2,985E-03 0,02237261 ! toxin metabolic process GO:0009404 11 6 0,000 2,985E-03 0,02230313 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 2,985E-03 0,02223408 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 2,985E-03 0,02216546 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 2,985E-03 0,02209726 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 2,985E-03 0,02202947 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 2,985E-03 0,0219621 ! cGMP-mediated signaling GO:0019934 13 6 0,000 2,985E-03 0,02189515 ! activation of MAPKKK activity GO:0000185 12 6 0,000 2,985E-03 0,0218286 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 2,985E-03 0,02176245 ! thymic T cell selection GO:0045061 12 6 0,000 2,985E-03 0,0216967 ! protein lipoylation GO:0009249 10 6 0,000 2,985E-03 0,02163135 ! cysteine metabolic process GO:0006534 10 6 0,000 2,985E-03 0,02156639 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 2,985E-03 0,02150182 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 2,985E-03 0,02143764 ! glutamate catabolic process GO:0006538 10 6 0,000 2,985E-03 0,02137383 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 2,985E-03 0,02131041 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 2,985E-03 0,02124736 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 2,985E-03 0,02118468 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 2,985E-03 0,02112238 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 2,985E-03 0,02106043 ! hyperosmotic response GO:0006972 9 6 0,000 2,985E-03 0,02099885 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 2,985E-03 0,02093763 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 2,985E-03 0,02087677 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 2,985E-03 0,02081626 ! urea metabolic process GO:0019627 7 6 0,000 2,985E-03 0,02075609 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 2,985E-03 0,02069628 ! neutrophil activation GO:0042119 8 6 0,000 2,985E-03 0,0206368 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 2,985E-03 0,02057767 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 2,985E-03 0,02051888 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 2,985E-03 0,02046042 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 2,985E-03 0,0204023 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 2,985E-03 0,0203445 ! neuron apoptosis GO:0051402 9 6 0,000 2,985E-03 0,02028703 ! nucleoside salvage GO:0043174 9 6 0,000 2,985E-03 0,02022988 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 2,985E-03 0,02017306 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 2,985E-03 0,02011655 ! T cell mediated immunity GO:0002456 16 6 0,000 2,985E-03 0,02006036 ! negative regulation of platelet activation GO:0010544 9 6 0,000 2,985E-03 0,02000448 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 2,985E-03 0,01994891 ! carnitine transport GO:0015879 10 6 0,000 2,985E-03 0,01989365 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 2,985E-03 0,0198387 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 2,985E-03 0,01978404 ! positive regulation of exocytosis GO:0045921 8 6 0,000 2,985E-03 0,01972969 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 2,985E-03 0,01967564 ! 5S class rRNA transcription GO:0042791 11 6 0,000 2,985E-03 0,01962188 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 2,985E-03 0,01956841 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 2,985E-03 0,01951524 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 2,985E-03 0,01946235 ! sodium ion homeostasis GO:0055078 11 6 0,000 2,985E-03 0,01940975 ! establishment of spindle localization GO:0051293 12 6 0,000 2,985E-03 0,01935743 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 2,985E-03 0,0193054 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 2,985E-03 0,01925364 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 2,985E-03 0,01920216 ! neural nucleus development GO:0048857 14 6 0,000 2,985E-03 0,01915095 ! response to UV-C GO:0010225 11 6 0,000 2,985E-03 0,01910002 ! astrocyte development GO:0014002 15 6 0,000 2,985E-03 0,01904936 ! protein targeting to lysosome GO:0006622 10 6 0,000 2,985E-03 0,01899896 ! purine base biosynthetic process GO:0009113 17 6 0,000 2,985E-03 0,01894883 ! interaction with symbiont GO:0051702 13 6 0,000 2,985E-03 0,01889897 ! regulation of dendrite development GO:0050773 16 6 0,000 2,985E-03 0,01884936 ! skeletal muscle contraction GO:0003009 6 6 0,000 2,985E-03 0,01880002 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 2,985E-03 0,01875093 ! response to copper ion GO:0046688 10 6 0,000 2,985E-03 0,0187021 ! response to exogenous dsRNA GO:0043330 10 6 0,000 2,985E-03 0,01865353 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 2,985E-03 0,0186052 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 2,985E-03 0,01855713 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 2,985E-03 0,0185093 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 2,985E-03 0,01846172 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 2,985E-03 0,01841438 ! regulation of dopamine secretion GO:0014059 14 6 0,000 2,985E-03 0,01836728 ! nucleoside catabolic process GO:0009164 7 6 0,000 2,985E-03 0,01832043 ! hair follicle maturation GO:0048820 7 6 0,000 2,985E-03 0,01827381 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 2,985E-03 0,01822743 ! Schwann cell development GO:0014044 15 6 0,000 2,985E-03 0,01818129 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 2,985E-03 0,01813537 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 2,985E-03 0,01808969 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 2,985E-03 0,01804424 ! subpallium development GO:0021544 10 6 0,000 2,985E-03 0,01799902 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 2,985E-03 0,01795402 ! histone ubiquitination GO:0016574 8 6 0,000 2,985E-03 0,01790925 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 2,985E-03 0,0178647 ! maintenance of organ identity GO:0048496 9 6 0,000 2,985E-03 0,01782037 ! G2 phase GO:0051319 16 6 0,000 2,985E-03 0,01777626 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 2,985E-03 0,01773237 ! establishment of planar polarity GO:0001736 7 6 0,000 2,985E-03 0,01768869 ! regulation of mast cell activation GO:0033003 12 6 0,000 2,985E-03 0,01764523 ! membrane to membrane docking GO:0022614 14 6 0,000 2,985E-03 0,01760198 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 2,985E-03 0,01755894 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 2,985E-03 0,01751612 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 2,985E-03 0,0174735 ! receptor internalization GO:0031623 10 6 0,000 2,985E-03 0,01743109 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 2,985E-03 0,01738888 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 2,985E-03 0,01734688 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 2,985E-03 0,01730508 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 2,985E-03 0,01726348 ! protein deubiquitination GO:0016579 14 6 0,000 2,985E-03 0,01722208 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 2,985E-03 0,01718088 ! protein destabilization GO:0031648 9 6 0,000 2,985E-03 0,01713988 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 2,985E-03 0,01709907 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 2,985E-03 0,01705845 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 2,985E-03 0,01701803 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 2,985E-03 0,0169778 ! progesterone metabolic process GO:0042448 10 6 0,000 2,985E-03 0,01693775 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 2,985E-03 0,0168979 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 2,985E-03 0,01685823 ! negative regulation of axon extension GO:0030517 21 6 0,000 2,985E-03 0,01681875 ! removal of superoxide radicals GO:0019430 11 6 0,000 2,985E-03 0,01677946 ! triglyceride catabolic process GO:0019433 10 6 0,000 2,985E-03 0,01674034 ! determination of adult lifespan GO:0008340 15 6 0,000 2,985E-03 0,01670141 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 2,985E-03 0,01666266 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 2,985E-03 0,01662409 ! cerebellar cortex formation GO:0021697 8 6 0,000 2,985E-03 0,0165857 ! catecholamine transport GO:0051937 9 6 0,000 2,985E-03 0,01654748 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 2,985E-03 0,01650944 ! sensory cilium assembly GO:0035058 10 6 0,000 2,985E-03 0,01647158 ! organ or tissue specific immune response GO:0002251 7 6 0,000 2,985E-03 0,01643389 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 2,985E-03 0,01639637 ! maternal placenta development GO:0001893 12 6 0,000 2,985E-03 0,01635902 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 2,985E-03 0,01632184 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 2,985E-03 0,01628483 ! negative regulation of B cell activation GO:0050869 13 6 0,000 2,985E-03 0,01624798 ! protein amino acid prenylation GO:0018346 16 6 0,000 2,985E-03 0,0162113 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 2,985E-03 0,01617479 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 2,985E-03 0,01613844 ! positive regulation of coagulation GO:0050820 12 6 0,000 2,985E-03 0,01610226 ! tRNA transcription GO:0009304 14 7 0,000 3,482E-03 0,01873959 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 3,482E-03 0,01869776 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 3,482E-03 0,01865612 ! behavioral response to cocaine GO:0048148 14 7 0,000 3,482E-03 0,01861466 ! regulation of helicase activity GO:0051095 15 7 0,000 3,482E-03 0,01857338 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 3,482E-03 0,01853229 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 3,482E-03 0,01849138 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 3,482E-03 0,01845065 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 3,482E-03 0,0184101 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 3,482E-03 0,01836973 ! prostate gland development GO:0030850 13 7 0,000 3,482E-03 0,01832953 ! nucleotide-sugar transport GO:0015780 12 7 0,000 3,482E-03 0,01828951 ! synaptonemal complex assembly GO:0007130 10 7 0,000 3,482E-03 0,01824966 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 3,482E-03 0,01820999 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 3,482E-03 0,01817049 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 3,482E-03 0,01813116 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 3,482E-03 0,018092 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 3,482E-03 0,01805301 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 3,482E-03 0,01801418 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 3,482E-03 0,01797553 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 3,482E-03 0,01793704 ! SMAD protein complex assembly GO:0007183 12 7 0,000 3,482E-03 0,01789871 ! glycolipid transport GO:0046836 10 7 0,000 3,482E-03 0,01786055 ! protein amino acid sulfation GO:0006477 10 7 0,000 3,482E-03 0,01782254 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 3,482E-03 0,0177847 ! neuron adhesion GO:0007158 12 7 0,000 3,482E-03 0,01774702 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 3,482E-03 0,0177095 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 3,482E-03 0,01767214 ! actin-myosin filament sliding GO:0033275 11 7 0,000 3,482E-03 0,01763494 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 3,482E-03 0,01759789 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 3,482E-03 0,017561 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 3,482E-03 0,01752426 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 3,482E-03 0,01748767 ! mRNA stabilization GO:0048255 18 7 0,000 3,482E-03 0,01745124 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 3,482E-03 0,01741496 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 3,482E-03 0,01737883 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 3,482E-03 0,01734285 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 3,482E-03 0,01730702 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 3,482E-03 0,01727133 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 3,482E-03 0,01723579 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 3,482E-03 0,0172004 ! lipoprotein transport GO:0042953 14 7 0,000 3,482E-03 0,01716516 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 3,482E-03 0,01713005 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 3,482E-03 0,01709509 ! rhythmic behavior GO:0007622 15 7 0,000 3,482E-03 0,01706028 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 3,482E-03 0,0170256 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 3,482E-03 0,01699107 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 3,482E-03 0,01695667 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 3,482E-03 0,01692242 ! regulation of odontogenesis GO:0042481 13 7 0,000 3,482E-03 0,0168883 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 3,482E-03 0,01685432 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 3,482E-03 0,01682047 ! mechanosensory behavior GO:0007638 14 7 0,000 3,482E-03 0,01678676 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 3,482E-03 0,01675319 ! positive regulation of isotype switching GO:0045830 15 7 0,000 3,482E-03 0,01671975 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 3,482E-03 0,01668645 ! protein-cofactor linkage GO:0018065 13 7 0,000 3,482E-03 0,01665327 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 3,482E-03 0,01662023 ! spinal cord patterning GO:0021511 13 7 0,000 3,482E-03 0,01658732 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 3,482E-03 0,01655454 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 3,482E-03 0,01652189 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 3,482E-03 0,01648936 ! adrenal gland development GO:0030325 17 7 0,000 3,482E-03 0,01645697 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 3,482E-03 0,0164247 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 3,482E-03 0,01639256 ! ovulation GO:0030728 9 7 0,000 3,482E-03 0,01636054 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 3,482E-03 0,01632865 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 3,482E-03 0,01629688 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 3,482E-03 0,01626523 ! microtubule nucleation GO:0007020 20 7 0,000 3,482E-03 0,01623371 ! proline biosynthetic process GO:0006561 10 7 0,000 3,482E-03 0,01620231 ! thyroid hormone generation GO:0006590 13 7 0,000 3,482E-03 0,01617103 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 3,482E-03 0,01613988 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 3,482E-03 0,01610884 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 3,482E-03 0,01607792 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 3,482E-03 0,01604712 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 3,482E-03 0,01601644 ! galactose metabolic process GO:0006012 13 7 0,000 3,482E-03 0,01598587 ! vesicle fusion GO:0006906 17 7 0,000 3,482E-03 0,01595542 ! response to dietary excess GO:0002021 8 7 0,000 3,482E-03 0,01592509 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 3,482E-03 0,01589487 ! intracellular pH reduction GO:0051452 11 7 0,000 3,482E-03 0,01586476 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 3,482E-03 0,01583477 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 3,482E-03 0,0158049 ! organ growth GO:0035265 15 7 0,000 3,482E-03 0,01577513 ! purine salvage GO:0043101 10 7 0,000 3,482E-03 0,01574548 ! nucleoside transport GO:0015858 8 7 0,000 3,482E-03 0,01571594 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 3,482E-03 0,01568651 ! parturition GO:0007567 14 7 0,000 3,482E-03 0,01565719 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 3,482E-03 0,01562798 ! rRNA modification GO:0000154 14 7 0,000 3,482E-03 0,01559887 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 3,482E-03 0,01556988 ! spindle checkpoint GO:0031577 15 7 0,000 3,482E-03 0,01554099 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 3,482E-03 0,01551221 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 3,482E-03 0,01548354 ! macrophage differentiation GO:0030225 11 7 0,000 3,482E-03 0,01545497 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 3,482E-03 0,01542651 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 3,482E-03 0,01539815 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 3,482E-03 0,0153699 ! hyaluronan metabolic process GO:0030212 8 7 0,000 3,482E-03 0,01534175 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 3,482E-03 0,0153137 ! anterograde axon cargo transport GO:0008089 18 7 0,000 3,482E-03 0,01528576 ! fibrinolysis GO:0042730 10 7 0,000 3,482E-03 0,01525792 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 3,482E-03 0,01523017 ! eating behavior GO:0042755 7 7 0,000 3,482E-03 0,01520253 ! B cell lineage commitment GO:0002326 21 7 0,000 3,482E-03 0,01517499 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 3,482E-03 0,01514755 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 3,482E-03 0,01512021 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 3,482E-03 0,01509297 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 3,482E-03 0,01506582 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 3,482E-03 0,01503877 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 3,482E-03 0,01501182 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 3,482E-03 0,01498497 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 3,482E-03 0,01495821 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 3,482E-03 0,01493154 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 3,482E-03 0,01490497 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 3,482E-03 0,0148785 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 3,482E-03 0,01485212 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 3,482E-03 0,01482583 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 3,482E-03 0,01479964 ! regulation of meiosis GO:0040020 12 7 0,000 3,482E-03 0,01477354 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 3,482E-03 0,01474753 ! T cell lineage commitment GO:0002360 16 7 0,000 3,482E-03 0,01472161 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 3,482E-03 0,01469578 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 3,482E-03 0,01467005 ! oxygen homeostasis GO:0032364 12 7 0,000 3,482E-03 0,0146444 ! transcription termination GO:0006353 13 7 0,000 3,482E-03 0,01461884 ! response to tumor cell GO:0002347 13 7 0,000 3,482E-03 0,01459337 ! regulation of respiratory burst GO:0060263 11 7 0,000 3,482E-03 0,01456799 ! coenzyme A metabolic process GO:0015936 12 7 0,000 3,482E-03 0,0145427 ! anaphase GO:0051322 17 7 0,000 3,482E-03 0,0145175 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 3,482E-03 0,01449238 ! axonal fasciculation GO:0007413 18 7 0,000 3,482E-03 0,01446735 ! negative regulation of nuclear division GO:0051784 14 7 0,000 3,482E-03 0,01444241 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 3,482E-03 0,01441755 ! peptidyl-threonine modification GO:0018210 25 7 0,000 3,482E-03 0,01439278 ! diuresis GO:0030146 12 7 0,000 3,482E-03 0,01436809 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 3,482E-03 0,01434349 ! thiamin metabolic process GO:0006772 7 7 0,000 3,482E-03 0,01431897 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 3,482E-03 0,01429453 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 3,482E-03 0,01427018 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 3,482E-03 0,01424591 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 3,482E-03 0,01422172 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 3,482E-03 0,01419762 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 3,482E-03 0,0141736 ! melanin biosynthetic process GO:0042438 8 7 0,000 3,482E-03 0,01414965 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 3,482E-03 0,01412579 ! dopamine biosynthetic process GO:0042416 18 7 0,000 3,482E-03 0,01410201 ! glycolipid catabolic process GO:0019377 15 7 0,000 3,482E-03 0,01407831 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 3,482E-03 0,01405469 ! lymph node development GO:0048535 10 7 0,000 3,482E-03 0,01403115 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 3,482E-03 0,01400769 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 3,482E-03 0,0139843 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 3,482E-03 0,01396099 ! endosome to lysosome transport GO:0008333 11 7 0,000 3,482E-03 0,01393776 ! protein modification by small protein removal GO:0070646 16 7 0,000 3,482E-03 0,01391461 ! adult feeding behavior GO:0008343 9 7 0,000 3,482E-03 0,01389154 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 3,482E-03 0,01386854 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 3,482E-03 0,01384561 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 3,482E-03 0,01382277 ! muscle adaptation GO:0043500 14 7 0,000 3,482E-03 0,01379999 ! embryonic heart tube development GO:0035050 10 7 0,000 3,482E-03 0,0137773 ! retina homeostasis GO:0001895 12 7 0,000 3,482E-03 0,01375467 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 3,482E-03 0,01373212 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 3,482E-03 0,01370965 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 3,482E-03 0,01368725 ! protein prenylation GO:0018342 18 7 0,000 3,482E-03 0,01366492 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 3,482E-03 0,01364266 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 3,482E-03 0,01362048 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 3,482E-03 0,01359837 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 3,978E-03 0,0155122 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 3,978E-03 0,0154871 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 3,978E-03 0,01546208 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 3,978E-03 0,01543714 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 3,978E-03 0,01541228 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 3,978E-03 0,0153875 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 3,978E-03 0,01536281 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 3,978E-03 0,01533819 ! neutral lipid catabolic process GO:0046461 13 8 0,000 3,978E-03 0,01531364 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 3,978E-03 0,01528918 ! meiotic prophase I GO:0007128 13 8 0,000 3,978E-03 0,0152648 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 3,978E-03 0,01524049 ! oligopeptide transport GO:0006857 15 8 0,000 3,978E-03 0,01521626 ! UTP metabolic process GO:0046051 8 8 0,000 3,978E-03 0,01519211 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 3,978E-03 0,01516803 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 3,978E-03 0,01514403 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 3,978E-03 0,01512011 ! macrophage chemotaxis GO:0048246 12 8 0,000 3,978E-03 0,01509626 ! succinate metabolic process GO:0006105 14 8 0,000 3,978E-03 0,01507248 ! membrane hyperpolarization GO:0060081 10 8 0,000 3,978E-03 0,01504879 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 3,978E-03 0,01502516 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 3,978E-03 0,01500161 ! T-helper 1 type immune response GO:0042088 12 8 0,000 3,978E-03 0,01497813 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 3,978E-03 0,01495473 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 3,978E-03 0,0149314 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 3,978E-03 0,01490814 ! ganglioside metabolic process GO:0001573 19 8 0,000 3,978E-03 0,01488496 ! reflex GO:0060004 16 8 0,000 3,978E-03 0,01486184 ! negative regulation of endocytosis GO:0045806 11 8 0,000 3,978E-03 0,0148388 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 3,978E-03 0,01481583 ! endothelial cell differentiation GO:0045446 17 8 0,000 3,978E-03 0,01479293 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 3,978E-03 0,0147701 ! glycerolipid catabolic process GO:0046503 13 8 0,000 3,978E-03 0,01474735 ! hemoglobin metabolic process GO:0020027 13 8 0,000 3,978E-03 0,01472466 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 3,978E-03 0,01470204 ! pigment granule organization GO:0048753 16 8 0,000 3,978E-03 0,01467949 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 3,978E-03 0,01465701 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 3,978E-03 0,0146346 ! astrocyte differentiation GO:0048708 18 8 0,000 3,978E-03 0,01461226 ! histidine metabolic process GO:0006547 16 8 0,000 3,978E-03 0,01458998 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 3,978E-03 0,01456777 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 3,978E-03 0,01454564 ! glycine catabolic process GO:0006546 13 8 0,000 3,978E-03 0,01452356 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 3,978E-03 0,01450156 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 3,978E-03 0,01447962 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 3,978E-03 0,01445775 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 3,978E-03 0,01443594 ! regulation of pigmentation during development GO:0048070 24 8 0,000 3,978E-03 0,0144142 ! melanin metabolic process GO:0006582 15 8 0,000 3,978E-03 0,01439252 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 3,978E-03 0,01437091 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 3,978E-03 0,01434937 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 3,978E-03 0,01432789 ! macrophage activation GO:0042116 12 8 0,000 3,978E-03 0,01430647 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 3,978E-03 0,01428512 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 3,978E-03 0,01426383 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 3,978E-03 0,0142426 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 3,978E-03 0,01422144 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 3,978E-03 0,01420034 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 3,978E-03 0,0141793 ! regulation of vascular permeability GO:0043114 12 8 0,000 3,978E-03 0,01415833 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 3,978E-03 0,01413741 ! osteoblast development GO:0002076 16 8 0,000 3,978E-03 0,01411656 ! positive regulation of vasodilation GO:0045909 13 8 0,000 3,978E-03 0,01409577 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 3,978E-03 0,01407504 ! negative regulation of translational initiation GO:0045947 10 8 0,000 3,978E-03 0,01405437 ! Schwann cell differentiation GO:0014037 19 8 0,000 3,978E-03 0,01403377 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 3,978E-03 0,01401322 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 3,978E-03 0,01399273 ! response to UV-B GO:0010224 16 8 0,000 3,978E-03 0,0139723 ! protein targeting to vacuole GO:0006623 12 8 0,000 3,978E-03 0,01395194 ! protein retention in ER lumen GO:0006621 14 8 0,000 3,978E-03 0,01393163 ! intermediate filament organization GO:0045109 12 8 0,000 3,978E-03 0,01391138 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 3,978E-03 0,01389119 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 3,978E-03 0,01387105 ! cellular extravasation GO:0045123 12 8 0,000 3,978E-03 0,01385098 ! cardiac muscle cell development GO:0055013 13 8 0,000 3,978E-03 0,01383097 ! regulation of circadian rhythm GO:0042752 16 8 0,000 3,978E-03 0,01381101 ! response to antibiotic GO:0046677 11 8 0,000 3,978E-03 0,01379111 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 3,978E-03 0,01377126 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 3,978E-03 0,01375148 ! DNA topological change GO:0006265 12 8 0,000 3,978E-03 0,01373175 ! response to tropane GO:0014073 15 8 0,000 3,978E-03 0,01371207 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 3,978E-03 0,01369246 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 3,978E-03 0,0136729 ! melanosome transport GO:0032402 13 8 0,000 3,978E-03 0,01365339 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 0,000 3,978E-03 0,01363394 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 3,978E-03 0,01361455 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 3,978E-03 0,01359521 ! mast cell activation GO:0045576 14 8 0,000 3,978E-03 0,01357593 ! multicellular organismal aging GO:0010259 18 8 0,000 3,978E-03 0,0135567 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 3,978E-03 0,01353752 ! dendrite morphogenesis GO:0048813 13 8 0,000 3,978E-03 0,0135184 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 3,978E-03 0,01349933 ! nucleosome disassembly GO:0006337 14 8 0,000 3,978E-03 0,01348032 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 3,978E-03 0,01346136 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 3,978E-03 0,01344245 ! leukocyte activation during immune response GO:0002366 13 8 0,000 3,978E-03 0,0134236 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 3,978E-03 0,0134048 ! establishment of chromosome localization GO:0051303 12 8 0,000 3,978E-03 0,01338605 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 3,978E-03 0,01336736 ! intracellular lipid transport GO:0032365 13 8 0,000 3,978E-03 0,01334871 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 3,978E-03 0,01333012 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 3,978E-03 0,01331158 ! regulation of macrophage activation GO:0043030 15 8 0,000 3,978E-03 0,01329309 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 3,978E-03 0,01327466 ! positive regulation of epidermis development GO:0045684 13 8 0,000 3,978E-03 0,01325627 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 3,978E-03 0,01323794 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 3,978E-03 0,01321965 ! hormone catabolic process GO:0042447 17 8 0,000 3,978E-03 0,01320142 ! positive regulation of glucose import GO:0046326 8 8 0,000 3,978E-03 0,01318323 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 3,978E-03 0,0131651 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 3,978E-03 0,01314702 ! ATP catabolic process GO:0006200 11 8 0,000 3,978E-03 0,01312898 ! blastocyst growth GO:0001832 19 8 0,000 3,978E-03 0,013111 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 3,978E-03 0,01309306 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 3,978E-03 0,01307517 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 3,978E-03 0,01305734 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 3,978E-03 0,01303955 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 3,978E-03 0,01302181 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 3,978E-03 0,01300411 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 3,978E-03 0,01298647 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 3,978E-03 0,01296887 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 3,978E-03 0,01295132 ! amino sugar catabolic process GO:0046348 10 8 0,000 3,978E-03 0,01293382 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 3,978E-03 0,01291637 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 3,978E-03 0,01289896 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 3,978E-03 0,0128816 ! behavioral response to nicotine GO:0035095 12 8 0,000 3,978E-03 0,01286428 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 3,978E-03 0,01284702 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 3,978E-03 0,0128298 ! NAD biosynthetic process GO:0009435 13 8 0,000 3,978E-03 0,01281262 ! regulation of developmental growth GO:0048638 15 9 0,000 4,474E-03 0,01439158 ! axon extension GO:0048675 15 9 0,000 4,474E-03 0,01437237 ! autophagic vacuole formation GO:0000045 15 9 0,000 4,474E-03 0,01435321 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 4,474E-03 0,01433409 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 4,474E-03 0,01431503 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 4,474E-03 0,01429602 ! pentose-phosphate shunt GO:0006098 16 9 0,000 4,474E-03 0,01427706 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 4,474E-03 0,01425815 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 4,474E-03 0,01423929 ! cell proliferation in forebrain GO:0021846 15 9 0,000 4,474E-03 0,01422048 ! phosphate transport GO:0006817 19 9 0,000 4,474E-03 0,01420172 ! reproductive behavior GO:0019098 19 9 0,000 4,474E-03 0,01418301 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 4,474E-03 0,01416435 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 4,474E-03 0,01414574 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 4,474E-03 0,01412717 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 4,474E-03 0,01410866 ! GTP metabolic process GO:0046039 9 9 0,000 4,474E-03 0,01409019 ! RNA methylation GO:0001510 15 9 0,000 4,474E-03 0,01407177 ! elastic fiber assembly GO:0048251 15 9 0,000 4,474E-03 0,0140534 ! induction of positive chemotaxis GO:0050930 15 9 0,000 4,474E-03 0,01403508 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 4,474E-03 0,0140168 ! artery development GO:0060840 24 9 0,000 4,474E-03 0,01399858 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 4,474E-03 0,0139804 ! regulation of glycolysis GO:0006110 21 9 0,000 4,474E-03 0,01396226 ! cerebral cortex cell migration GO:0021795 15 9 0,000 4,474E-03 0,01394418 ! keratinocyte proliferation GO:0043616 14 9 0,000 4,474E-03 0,01392614 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 4,474E-03 0,01390815 ! chemosensory behavior GO:0007635 20 9 0,000 4,474E-03 0,0138902 ! microtubule bundle formation GO:0001578 21 9 0,000 4,474E-03 0,0138723 ! middle ear morphogenesis GO:0042474 14 9 0,000 4,474E-03 0,01385445 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 4,474E-03 0,01383664 ! leukocyte degranulation GO:0043299 16 9 0,000 4,474E-03 0,01381888 ! bile acid and bile salt transport GO:0015721 13 9 0,000 4,474E-03 0,01380116 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 4,474E-03 0,01378349 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 4,474E-03 0,01376586 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 4,474E-03 0,01374828 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 4,474E-03 0,01373075 ! protein targeting to ER GO:0045047 22 9 0,000 4,474E-03 0,01371325 ! ceramide biosynthetic process GO:0046513 19 9 0,000 4,474E-03 0,01369581 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 4,474E-03 0,0136784 ! T cell selection GO:0045058 23 9 0,000 4,474E-03 0,01366105 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 4,474E-03 0,01364373 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 4,474E-03 0,01362646 ! phosphagen metabolic process GO:0006599 12 9 0,000 4,474E-03 0,01360923 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 4,474E-03 0,01359205 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 4,474E-03 0,01357491 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 4,474E-03 0,01355781 ! regulation of type I interferon production GO:0032479 12 9 0,000 4,474E-03 0,01354076 ! mannose metabolic process GO:0006013 13 9 0,000 4,474E-03 0,01352375 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 4,474E-03 0,01350678 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 4,474E-03 0,01348986 ! Rac protein signal transduction GO:0016601 17 9 0,000 4,474E-03 0,01347297 ! receptor clustering GO:0043113 18 9 0,000 4,474E-03 0,01345613 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 4,474E-03 0,01343933 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 4,474E-03 0,01342257 ! ruffle organization GO:0031529 15 9 0,000 4,474E-03 0,01340586 ! retinol metabolic process GO:0042572 18 9 0,000 4,474E-03 0,01338918 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 4,474E-03 0,01337255 ! behavioral fear response GO:0001662 22 9 0,000 4,474E-03 0,01335596 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 4,474E-03 0,01333941 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 4,474E-03 0,0133229 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 4,474E-03 0,01330643 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 4,474E-03 0,01329001 ! protein heterooligomerization GO:0051291 16 9 0,000 4,474E-03 0,01327362 ! oligodendrocyte development GO:0014003 10 9 0,000 4,474E-03 0,01325727 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 4,474E-03 0,01324097 ! segment specification GO:0007379 13 9 0,000 4,474E-03 0,0132247 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 4,474E-03 0,01320847 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 4,474E-03 0,01319229 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 4,474E-03 0,01317614 ! response to amine stimulus GO:0014075 13 9 0,000 4,474E-03 0,01316003 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 4,474E-03 0,01314396 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 4,474E-03 0,01312793 ! erythrocyte development GO:0048821 15 9 0,000 4,474E-03 0,01311194 ! gas homeostasis GO:0033483 16 9 0,000 4,474E-03 0,01309599 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 4,474E-03 0,01308008 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 4,474E-03 0,0130642 ! renal water homeostasis GO:0003091 14 9 0,000 4,474E-03 0,01304837 ! postreplication repair GO:0006301 22 9 0,000 4,474E-03 0,01303257 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 4,474E-03 0,01301681 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 4,474E-03 0,01300109 ! icosanoid secretion GO:0032309 15 9 0,000 4,474E-03 0,01298541 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 4,474E-03 0,01296976 ! cerebellum morphogenesis GO:0021587 14 9 0,000 4,474E-03 0,01295416 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 4,474E-03 0,01293859 ! regulation of cell division GO:0051302 15 9 0,000 4,474E-03 0,01292305 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 4,474E-03 0,01290756 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 4,474E-03 0,0128921 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 4,474E-03 0,01287668 ! sterol catabolic process GO:0016127 11 9 0,000 4,474E-03 0,0128613 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 4,474E-03 0,01284595 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 4,474E-03 0,01283064 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 4,474E-03 0,01281536 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 4,474E-03 0,01280012 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 4,474E-03 0,01278492 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 4,474E-03 0,01276976 ! musculoskeletal movement GO:0050881 14 9 0,000 4,474E-03 0,01275463 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 4,474E-03 0,01273953 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 4,474E-03 0,01272447 ! regulation of synaptogenesis GO:0051963 15 9 0,000 4,474E-03 0,01270945 ! purine base metabolic process GO:0006144 21 9 0,000 4,474E-03 0,01269446 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 4,474E-03 0,01267951 ! pigment granule transport GO:0051904 17 9 0,000 4,474E-03 0,01266459 ! regulation of fibrinolysis GO:0051917 16 9 0,000 4,474E-03 0,01264971 ! regulation of telomere maintenance GO:0032204 14 9 0,000 4,474E-03 0,01263486 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 4,474E-03 0,01262005 ! regulation of muscle adaptation GO:0043502 14 9 0,000 4,474E-03 0,01260527 ! regulation of amino acid transport GO:0051955 11 9 0,000 4,474E-03 0,01259053 ! mitochondrion localization GO:0051646 15 9 0,000 4,474E-03 0,01257582 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 4,97E-03 0,01395359 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 4,97E-03 0,01393733 ! negative regulation of blood pressure GO:0045776 26 10 0,000 4,97E-03 0,0139211 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 4,97E-03 0,01390491 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 4,97E-03 0,01388876 ! regulation of phosphatase activity GO:0010921 28 10 0,000 4,97E-03 0,01387265 ! synapsis GO:0007129 13 10 0,000 4,97E-03 0,01385658 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 4,97E-03 0,01384054 ! N-glycan processing GO:0006491 20 10 0,000 4,97E-03 0,01382454 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 4,97E-03 0,01380858 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 4,97E-03 0,01379265 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 4,97E-03 0,01377676 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 4,97E-03 0,0137609 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 4,97E-03 0,01374509 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 4,97E-03 0,01372931 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 4,97E-03 0,01371356 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 4,97E-03 0,01369785 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 4,97E-03 0,01368218 ! androgen metabolic process GO:0008209 17 10 0,000 4,97E-03 0,01366654 ! phospholipid efflux GO:0033700 16 10 0,000 4,97E-03 0,01365094 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 4,97E-03 0,01363538 ! positive regulation of heart contraction GO:0045823 16 10 0,000 4,97E-03 0,01361985 ! lung alveolus development GO:0048286 26 10 0,000 4,97E-03 0,01360435 ! pathogenesis GO:0009405 13 10 0,000 4,97E-03 0,01358889 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 4,97E-03 0,01357347 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 4,97E-03 0,01355808 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 4,97E-03 0,01354272 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 4,97E-03 0,01352741 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 4,97E-03 0,01351212 ! endoderm development GO:0007492 16 10 0,000 4,97E-03 0,01349687 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 4,97E-03 0,01348165 ! arginine catabolic process GO:0006527 13 10 0,000 4,97E-03 0,01346647 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 4,97E-03 0,01345132 ! proline metabolic process GO:0006560 13 10 0,000 4,97E-03 0,01343621 ! glucan biosynthetic process GO:0009250 14 10 0,000 4,97E-03 0,01342113 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 4,97E-03 0,01340608 ! polyamine biosynthetic process GO:0006596 12 10 0,000 4,97E-03 0,01339107 ! V(D)J recombination GO:0033151 28 10 0,000 4,97E-03 0,01337609 ! reverse cholesterol transport GO:0043691 16 10 0,000 4,97E-03 0,01336115 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 4,97E-03 0,01334623 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 4,97E-03 0,01333136 ! B cell proliferation GO:0042100 18 10 0,000 4,97E-03 0,01331651 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 4,97E-03 0,0133017 ! regulation of sodium ion transport GO:0002028 21 10 0,000 4,97E-03 0,01328692 ! multicellular organism growth GO:0035264 18 10 0,000 4,97E-03 0,01327217 ! phagocytosis, engulfment GO:0006911 28 10 0,000 4,97E-03 0,01325746 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 4,97E-03 0,01324278 ! epithelial cell development GO:0002064 20 10 0,000 4,97E-03 0,01322813 ! lens development in camera-type eye GO:0002088 16 10 0,000 4,97E-03 0,01321351 ! retinoic acid metabolic process GO:0042573 14 10 0,000 4,97E-03 0,01319893 ! macroautophagy GO:0016236 17 10 0,000 4,97E-03 0,01318437 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 4,97E-03 0,01316985 ! positive regulation of translational initiation GO:0045948 11 10 0,000 4,97E-03 0,01315536 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 4,97E-03 0,01314091 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 4,97E-03 0,01312648 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 4,97E-03 0,01311209 ! copper ion homeostasis GO:0055070 13 10 0,000 4,97E-03 0,01309773 ! regulation of bone resorption GO:0045124 25 10 0,000 4,97E-03 0,0130834 ! regulation of gliogenesis GO:0014013 23 10 0,000 4,97E-03 0,0130691 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 4,97E-03 0,01305483 ! alpha-beta T cell activation GO:0046631 23 10 0,000 4,97E-03 0,0130406 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 4,97E-03 0,01302639 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 4,97E-03 0,01301222 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 4,97E-03 0,01299807 ! blastoderm segmentation GO:0007350 18 10 0,000 4,97E-03 0,01298396 ! response to dsRNA GO:0043331 20 10 0,000 4,97E-03 0,01296988 ! DNA ligation GO:0006266 19 10 0,000 4,97E-03 0,01295582 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 4,97E-03 0,0129418 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 4,97E-03 0,01292781 ! melanosome localization GO:0032400 16 10 0,000 4,97E-03 0,01291385 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 4,97E-03 0,01289992 ! regulation of B cell differentiation GO:0045577 19 10 0,000 4,97E-03 0,01288602 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 4,97E-03 0,01287215 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 4,97E-03 0,01285831 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 4,97E-03 0,0128445 ! mRNA cleavage GO:0006379 17 10 0,000 4,97E-03 0,01283071 ! protein sumoylation GO:0016925 15 10 0,000 4,97E-03 0,01281696 ! hindbrain morphogenesis GO:0021575 19 10 0,000 4,97E-03 0,01280324 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 4,97E-03 0,01278955 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 4,97E-03 0,01277588 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 4,97E-03 0,01276225 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 4,97E-03 0,01274864 ! salivary gland development GO:0007431 27 10 0,000 4,97E-03 0,01273507 ! prophase GO:0051324 15 10 0,000 4,97E-03 0,01272152 ! negative regulation of neurological system process GO:0031645 19 10 0,000 4,97E-03 0,012708 ! apical protein localization GO:0045176 15 10 0,000 4,97E-03 0,01269451 ! ubiquinone metabolic process GO:0006743 15 10 0,000 4,97E-03 0,01268105 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 4,97E-03 0,01266761 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 4,97E-03 0,01265421 ! midbrain development GO:0030901 13 10 0,000 4,97E-03 0,01264083 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 4,97E-03 0,01262748 ! methionine biosynthetic process GO:0009086 19 10 0,000 4,97E-03 0,01261416 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 4,97E-03 0,01260087 ! quaternary ammonium group transport GO:0015697 21 10 0,000 4,97E-03 0,01258761 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 4,97E-03 0,01257437 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 4,97E-03 0,01256116 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 4,97E-03 0,01254798 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 4,97E-03 0,01253483 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 4,97E-03 0,0125217 ! oocyte development GO:0048599 17 10 0,000 4,97E-03 0,0125086 ! establishment of pigment granule localization GO:0051905 18 10 0,000 4,97E-03 0,01249553 ! blastocyst formation GO:0001825 17 10 0,000 4,97E-03 0,01248249 ! cerebellar cortex development GO:0021695 15 10 0,000 4,97E-03 0,01246947 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 4,97E-03 0,01245649 ! activation of innate immune response GO:0002218 12 10 0,000 4,97E-03 0,01244352 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 4,97E-03 0,01243059 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 4,97E-03 0,01241768 ! response to nicotine GO:0035094 20 10 0,000 4,97E-03 0,0124048 ! establishment of cell polarity GO:0030010 16 10 0,000 4,97E-03 0,01239194 ! negative regulation of immune effector process GO:0002698 20 10 0,000 4,97E-03 0,01237912 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 4,97E-03 0,01236631 ! localization within membrane GO:0051668 20 10 0,000 4,97E-03 0,01235354 ! negative regulation of muscle development GO:0048635 20 11 0,000 5,466E-03 0,01357172 ! respiratory burst GO:0045730 17 11 0,000 5,466E-03 0,01355772 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 5,466E-03 0,01354376 ! neuron fate specification GO:0048665 17 11 0,000 5,466E-03 0,01352983 ! telencephalon cell migration GO:0022029 20 11 0,000 5,466E-03 0,01351592 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 5,466E-03 0,01350205 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 5,466E-03 0,0134882 ! thyroid gland development GO:0030878 26 11 0,000 5,466E-03 0,01347438 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 5,466E-03 0,01346059 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 5,466E-03 0,01344682 ! Golgi vesicle budding GO:0048194 22 11 0,000 5,466E-03 0,01343309 ! response to pain GO:0048265 24 11 0,000 5,466E-03 0,01341938 ! detection of mechanical stimulus GO:0050982 22 11 0,000 5,466E-03 0,0134057 ! T cell proliferation GO:0042098 26 11 0,000 5,466E-03 0,01339205 ! blood vessel remodeling GO:0001974 29 11 0,000 5,466E-03 0,01337843 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 5,466E-03 0,01336483 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 5,466E-03 0,01335126 ! bone resorption GO:0045453 16 11 0,000 5,466E-03 0,01333772 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 5,466E-03 0,01332421 ! ventral spinal cord development GO:0021517 21 11 0,000 5,466E-03 0,01331072 ! negative regulation of proteolysis GO:0045861 25 11 0,000 5,466E-03 0,01329726 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 5,466E-03 0,01328383 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 5,466E-03 0,01327043 ! melanocyte differentiation GO:0030318 21 11 0,000 5,466E-03 0,01325705 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 5,466E-03 0,0132437 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 5,466E-03 0,01323038 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 5,466E-03 0,01321708 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 5,466E-03 0,01320381 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 5,466E-03 0,01319056 ! lipid digestion GO:0044241 18 11 0,000 5,466E-03 0,01317735 ! substrate-bound cell migration GO:0006929 13 11 0,000 5,466E-03 0,01316416 ! UV protection GO:0009650 19 11 0,000 5,466E-03 0,01315099 ! adult heart development GO:0007512 14 11 0,000 5,466E-03 0,01313786 ! chondrocyte differentiation GO:0002062 24 11 0,000 5,466E-03 0,01312474 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 5,466E-03 0,01311166 ! temperature homeostasis GO:0001659 17 11 0,000 5,466E-03 0,0130986 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 5,466E-03 0,01308557 ! negative regulation of ossification GO:0030279 26 11 0,000 5,466E-03 0,01307256 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 5,466E-03 0,01305958 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 5,466E-03 0,01304662 ! regulation of organ growth GO:0046620 13 11 0,000 5,466E-03 0,01303369 ! pigment granule localization GO:0051875 20 11 0,000 5,466E-03 0,01302079 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 5,466E-03 0,01300791 ! vasoconstriction GO:0042310 18 11 0,000 5,466E-03 0,01299505 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 5,466E-03 0,01298222 ! embryonic axis specification GO:0000578 18 11 0,000 5,466E-03 0,01296942 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 5,466E-03 0,01295664 ! snRNA metabolic process GO:0016073 24 11 0,000 5,466E-03 0,01294389 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 5,466E-03 0,01293116 ! nitric oxide metabolic process GO:0046209 15 11 0,000 5,466E-03 0,01291846 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 5,466E-03 0,01290578 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 5,466E-03 0,01289313 ! zymogen activation GO:0031638 15 11 0,000 5,466E-03 0,0128805 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 5,466E-03 0,0128679 ! neuroblast proliferation GO:0007405 24 11 0,000 5,466E-03 0,01285532 ! nucleosome positioning GO:0016584 15 11 0,000 5,466E-03 0,01284277 ! regulation of isotype switching GO:0045191 22 11 0,000 5,466E-03 0,01283024 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 5,466E-03 0,01281773 ! glutathione biosynthetic process GO:0006750 13 11 0,000 5,466E-03 0,01280525 ! regulation of leukocyte migration GO:0002685 26 11 0,000 5,466E-03 0,01279279 ! acid secretion GO:0046717 18 11 0,000 5,466E-03 0,01278036 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 5,466E-03 0,01276795 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 5,466E-03 0,01275557 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 5,466E-03 0,01274321 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 5,466E-03 0,01273087 ! oocyte differentiation GO:0009994 18 11 0,000 5,466E-03 0,01271856 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 5,466E-03 0,01270627 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 5,466E-03 0,01269401 ! cholesterol efflux GO:0033344 19 11 0,000 5,466E-03 0,01268177 ! anterior/posterior axis specification GO:0009948 18 11 0,000 5,466E-03 0,01266955 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 5,466E-03 0,01265736 ! negative regulation of glucose import GO:0046325 17 11 0,000 5,466E-03 0,01264519 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 5,466E-03 0,01263304 ! embryonic gut development GO:0048566 15 11 0,000 5,466E-03 0,01262091 ! regulation of organic acid transport GO:0032890 18 11 0,000 5,466E-03 0,01260881 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 5,466E-03 0,01259674 ! cardiac cell differentiation GO:0035051 31 11 0,000 5,466E-03 0,01258468 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 5,466E-03 0,01257265 ! defense response to fungus GO:0050832 13 11 0,000 5,466E-03 0,01256064 ! developmental induction GO:0031128 19 11 0,000 5,466E-03 0,01254866 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 5,466E-03 0,01253669 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 5,466E-03 0,01252476 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 5,466E-03 0,01251284 ! sequestering of metal ion GO:0051238 14 11 0,000 5,466E-03 0,01250094 ! lamellipodium assembly GO:0030032 20 11 0,000 5,466E-03 0,01248907 ! regulation of embryonic development GO:0045995 27 11 0,000 5,466E-03 0,01247722 ! nucleus localization GO:0051647 19 11 0,000 5,466E-03 0,0124654 ! regulation of synapse organization GO:0050807 17 11 0,000 5,466E-03 0,01245359 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 5,961E-03 0,01356973 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 5,961E-03 0,0135569 ! positive regulation of blood pressure GO:0045777 17 12 0,000 5,961E-03 0,0135441 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 5,961E-03 0,01353133 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 5,961E-03 0,01351857 ! virus-host interaction GO:0019048 29 12 0,000 5,961E-03 0,01350584 ! regulation of B cell proliferation GO:0030888 20 12 0,000 5,961E-03 0,01349314 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 5,961E-03 0,01348046 ! cartilage condensation GO:0001502 20 12 0,000 5,961E-03 0,0134678 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 5,961E-03 0,01345516 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 5,961E-03 0,01344255 ! protein complex disassembly GO:0043241 27 12 0,000 5,961E-03 0,01342997 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 5,961E-03 0,0134174 ! regulation of cell projection assembly GO:0060491 30 12 0,000 5,961E-03 0,01340486 ! hippocampus development GO:0021766 26 12 0,000 5,961E-03 0,01339235 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 5,961E-03 0,01337986 ! cytokine biosynthetic process GO:0042089 21 12 0,000 5,961E-03 0,01336739 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 5,961E-03 0,01335494 ! positive regulation of cell growth GO:0030307 22 12 0,000 5,961E-03 0,01334252 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 5,961E-03 0,01333012 ! regulation of exit from mitosis GO:0007096 17 12 0,000 5,961E-03 0,01331774 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 5,961E-03 0,01330538 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 5,961E-03 0,01329305 ! drug transport GO:0015893 16 12 0,000 5,961E-03 0,01328075 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 5,961E-03 0,01326846 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 5,961E-03 0,0132562 ! tyrosine metabolic process GO:0006570 16 12 0,000 5,961E-03 0,01324396 ! polyamine metabolic process GO:0006595 17 12 0,000 5,961E-03 0,01323174 ! focal adhesion formation GO:0048041 35 12 0,000 5,961E-03 0,01321954 ! mitotic spindle organization GO:0007052 21 12 0,000 5,961E-03 0,01320737 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 5,961E-03 0,01319522 ! forebrain cell migration GO:0021885 21 12 0,000 5,961E-03 0,01318309 ! asymmetric protein localization GO:0008105 20 12 0,000 5,961E-03 0,01317099 ! membrane protein proteolysis GO:0033619 25 12 0,000 5,961E-03 0,0131589 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 5,961E-03 0,01314684 ! entry into host cell GO:0030260 32 12 0,000 5,961E-03 0,0131348 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 5,961E-03 0,01312279 ! monoamine transport GO:0015844 18 12 0,000 5,961E-03 0,01311079 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 5,961E-03 0,01309882 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 5,961E-03 0,01308687 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 5,961E-03 0,01307494 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 5,961E-03 0,01306303 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 5,961E-03 0,01305114 ! protein targeting to peroxisome GO:0006625 23 12 0,000 5,961E-03 0,01303928 ! protein homotetramerization GO:0051289 21 12 0,000 5,961E-03 0,01302743 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 5,961E-03 0,01301561 ! regulation of phagocytosis GO:0050764 16 12 0,000 5,961E-03 0,01300381 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 5,961E-03 0,01299203 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 5,961E-03 0,01298028 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 5,961E-03 0,01296854 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 5,961E-03 0,01295682 ! cranial nerve development GO:0021545 20 12 0,000 5,961E-03 0,01294513 ! fucose catabolic process GO:0019317 22 12 0,000 5,961E-03 0,01293346 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 5,961E-03 0,01292181 ! histone acetylation GO:0016573 26 12 0,000 5,961E-03 0,01291018 ! histone methylation GO:0016571 26 12 0,000 5,961E-03 0,01289857 ! mRNA polyadenylation GO:0006378 23 12 0,000 5,961E-03 0,01288698 ! autonomic nervous system development GO:0048483 24 12 0,000 5,961E-03 0,01287541 ! gland morphogenesis GO:0022612 29 12 0,000 5,961E-03 0,01286386 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 5,961E-03 0,01285233 ! peptidyl-lysine modification GO:0018205 21 12 0,000 5,961E-03 0,01284083 ! T cell homeostasis GO:0043029 25 12 0,000 5,961E-03 0,01282934 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 5,961E-03 0,01281788 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 5,961E-03 0,01280643 ! spleen development GO:0048536 22 12 0,000 5,961E-03 0,01279501 ! digestive tract morphogenesis GO:0048546 26 12 0,000 5,961E-03 0,01278361 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 5,961E-03 0,01277222 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 5,961E-03 0,01276086 ! regulation of RNA splicing GO:0043484 20 12 0,000 5,961E-03 0,01274952 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 5,961E-03 0,01273819 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 5,961E-03 0,01272689 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 5,961E-03 0,01271561 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 5,961E-03 0,01270434 ! response to cold GO:0009409 17 12 0,000 5,961E-03 0,0126931 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 5,961E-03 0,01268188 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 5,961E-03 0,01267068 ! cGMP metabolic process GO:0046068 18 13 0,000 6,457E-03 0,01371126 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 6,457E-03 0,01369917 ! regulation of chemokine production GO:0032642 18 13 0,000 6,457E-03 0,0136871 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 6,457E-03 0,01367505 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 6,457E-03 0,01366303 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 6,457E-03 0,01365102 ! lipid localization GO:0010876 28 13 0,000 6,457E-03 0,01363904 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 6,457E-03 0,01362707 ! organelle fusion GO:0048284 32 13 0,000 6,457E-03 0,01361513 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 6,457E-03 0,01360321 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 6,457E-03 0,01359131 ! pseudouridine synthesis GO:0001522 17 13 0,000 6,457E-03 0,01357943 ! endocrine pancreas development GO:0031018 22 13 0,000 6,457E-03 0,01356757 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 6,457E-03 0,01355573 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 6,457E-03 0,01354391 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 6,457E-03 0,01353211 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 6,457E-03 0,01352033 ! methionine metabolic process GO:0006555 27 13 0,000 6,457E-03 0,01350858 ! plasma membrane organization GO:0007009 24 13 0,000 6,457E-03 0,01349684 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 6,457E-03 0,01348512 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 6,457E-03 0,01347343 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 6,457E-03 0,01346175 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 6,457E-03 0,0134501 ! cell-cell junction assembly GO:0007043 27 13 0,000 6,457E-03 0,01343846 ! response to X-ray GO:0010165 25 13 0,000 6,457E-03 0,01342685 ! cytokine metabolic process GO:0042107 22 13 0,000 6,457E-03 0,01341525 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 6,457E-03 0,01340368 ! exocrine system development GO:0035272 32 13 0,000 6,457E-03 0,01339212 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 6,457E-03 0,01338059 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 6,457E-03 0,01336907 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 6,457E-03 0,01335758 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 6,457E-03 0,0133461 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 6,457E-03 0,01333465 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 6,457E-03 0,01332321 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 6,457E-03 0,01331179 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 6,457E-03 0,0133004 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 6,457E-03 0,01328902 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 6,457E-03 0,01327766 ! regulation of cellular pH GO:0030641 22 13 0,000 6,457E-03 0,01326632 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 6,457E-03 0,013255 ! ribosome assembly GO:0042255 17 13 0,000 6,457E-03 0,0132437 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 6,457E-03 0,01323242 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 6,457E-03 0,01322116 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 6,457E-03 0,01320992 ! chromatin silencing GO:0006342 26 13 0,000 6,457E-03 0,01319869 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 6,457E-03 0,01318749 ! regulation of epidermis development GO:0045682 19 13 0,000 6,457E-03 0,0131763 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 6,457E-03 0,01316514 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 6,457E-03 0,01315399 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 6,457E-03 0,01314286 ! regulation of mRNA stability GO:0043488 31 13 0,000 6,457E-03 0,01313175 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 6,457E-03 0,01312066 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 6,457E-03 0,01310959 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 6,457E-03 0,01309853 ! mRNA 3'-end processing GO:0031124 24 13 0,000 6,457E-03 0,0130875 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 6,457E-03 0,01307648 ! embryonic placenta development GO:0001892 23 13 0,000 6,457E-03 0,01306549 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 6,457E-03 0,01305451 ! insulin secretion GO:0030073 23 13 0,000 6,457E-03 0,01304355 ! actin filament polymerization GO:0030041 24 13 0,000 6,457E-03 0,0130326 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 6,457E-03 0,01302168 ! acrosome reaction GO:0007340 18 13 0,000 6,457E-03 0,01301077 ! rRNA transcription GO:0009303 25 14 0,000 6,952E-03 0,01399662 ! lactation GO:0007595 26 14 0,000 6,952E-03 0,01398492 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 6,952E-03 0,01397324 ! reproductive cellular process GO:0048610 20 14 0,000 6,952E-03 0,01396157 ! tRNA modification GO:0006400 20 14 0,000 6,952E-03 0,01394993 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 6,952E-03 0,0139383 ! regulation of S phase GO:0033261 23 14 0,000 6,952E-03 0,0139267 ! water transport GO:0006833 21 14 0,000 6,952E-03 0,01391511 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 6,952E-03 0,01390355 ! non-recombinational repair GO:0000726 25 14 0,000 6,952E-03 0,013892 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 6,952E-03 0,01388047 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 6,952E-03 0,01386896 ! retina development in camera-type eye GO:0060041 27 14 0,000 6,952E-03 0,01385747 ! hair follicle morphogenesis GO:0031069 26 14 0,000 6,952E-03 0,013846 ! RNA polyadenylation GO:0043631 30 14 0,000 6,952E-03 0,01383455 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 6,952E-03 0,01382311 ! palate development GO:0060021 31 14 0,000 6,952E-03 0,0138117 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 6,952E-03 0,0138003 ! regulated secretory pathway GO:0045055 23 14 0,000 6,952E-03 0,01378892 ! regulation of mRNA processing GO:0050684 24 14 0,000 6,952E-03 0,01377757 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 6,952E-03 0,01376623 ! arginine metabolic process GO:0006525 17 14 0,000 6,952E-03 0,01375491 ! regulation of heart rate GO:0002027 24 14 0,000 6,952E-03 0,0137436 ! organic alcohol transport GO:0015850 29 14 0,000 6,952E-03 0,01373232 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 6,952E-03 0,01372105 ! negative regulation of caspase activity GO:0043154 22 14 0,000 6,952E-03 0,01370981 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 6,952E-03 0,01369858 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 6,952E-03 0,01368737 ! neutral amino acid transport GO:0015804 26 14 0,000 6,952E-03 0,01367618 ! L-amino acid transport GO:0015807 30 14 0,000 6,952E-03 0,013665 ! bone mineralization GO:0030282 17 14 0,000 6,952E-03 0,01365385 ! stem cell development GO:0048864 43 14 0,000 6,952E-03 0,01364271 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 6,952E-03 0,01363159 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 6,952E-03 0,01362049 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 6,952E-03 0,01360941 ! cerebellum development GO:0021549 21 14 0,000 6,952E-03 0,01359835 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 6,952E-03 0,0135873 ! negative regulation of protein secretion GO:0050709 28 14 0,000 6,952E-03 0,01357627 ! response to gamma radiation GO:0010332 28 14 0,000 6,952E-03 0,01356526 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 6,952E-03 0,01355427 ! cofactor transport GO:0051181 26 14 0,000 6,952E-03 0,01354329 ! NADP metabolic process GO:0006739 24 14 0,000 6,952E-03 0,01353233 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 6,952E-03 0,0135214 ! protein-chromophore linkage GO:0018298 19 14 0,000 6,952E-03 0,01351047 ! intestinal absorption GO:0050892 25 14 0,000 6,952E-03 0,01349957 ! cAMP biosynthetic process GO:0006171 23 14 0,000 6,952E-03 0,01348868 ! oxygen transport GO:0015671 21 14 0,000 6,952E-03 0,01347781 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 6,952E-03 0,01346696 ! male genitalia development GO:0030539 24 14 0,000 6,952E-03 0,01345613 ! regulation of RNA stability GO:0043487 32 14 0,000 6,952E-03 0,01344531 ! regulation of axon extension GO:0030516 37 14 0,000 6,952E-03 0,01343451 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 6,952E-03 0,01342373 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 6,952E-03 0,01341296 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 7,447E-03 0,01435618 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 7,447E-03 0,01434469 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 7,447E-03 0,01433321 ! superoxide anion generation GO:0042554 20 15 0,000 7,447E-03 0,01432175 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 7,447E-03 0,01431032 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 7,447E-03 0,01429889 ! phospholipid catabolic process GO:0009395 22 15 0,000 7,447E-03 0,01428749 ! copper ion transport GO:0006825 20 15 0,000 7,447E-03 0,01427611 ! heterophilic cell adhesion GO:0007157 39 15 0,000 7,447E-03 0,01426474 ! cardiac muscle contraction GO:0060048 26 15 0,000 7,447E-03 0,01425339 ! sulfate transport GO:0008272 23 15 0,000 7,447E-03 0,01424206 ! response to cAMP GO:0051591 22 15 0,000 7,447E-03 0,01423075 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 7,447E-03 0,01421946 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 7,447E-03 0,01420818 ! ciliary or flagellar motility GO:0001539 20 15 0,000 7,447E-03 0,01419692 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 7,447E-03 0,01418568 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 7,447E-03 0,01417446 ! response to hexose stimulus GO:0009746 22 15 0,000 7,447E-03 0,01416325 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 7,447E-03 0,01415207 ! glycoprotein catabolic process GO:0006516 26 15 0,000 7,447E-03 0,0141409 ! pituitary gland development GO:0021983 29 15 0,000 7,447E-03 0,01412974 ! vesicle coating GO:0006901 33 15 0,000 7,447E-03 0,01411861 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 7,447E-03 0,01410749 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 7,447E-03 0,01409639 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 7,447E-03 0,01408531 ! regulation of exocytosis GO:0017157 22 15 0,000 7,447E-03 0,01407425 ! G1/S transition checkpoint GO:0031575 40 15 0,000 7,447E-03 0,0140632 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 7,447E-03 0,01405217 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 7,447E-03 0,01404116 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 7,447E-03 0,01403016 ! regulation of vasodilation GO:0042312 26 15 0,000 7,447E-03 0,01401918 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 7,447E-03 0,01400822 ! histone deacetylation GO:0016575 20 15 0,000 7,447E-03 0,01399728 ! mRNA splice site selection GO:0006376 38 15 0,000 7,447E-03 0,01398635 ! tissue regeneration GO:0042246 26 15 0,000 7,447E-03 0,01397544 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 7,447E-03 0,01396455 ! water homeostasis GO:0030104 27 15 0,000 7,447E-03 0,01395367 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 7,447E-03 0,01394281 ! muscle maintenance GO:0046716 26 15 0,000 7,447E-03 0,01393197 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 7,447E-03 0,01392115 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 7,447E-03 0,01391034 ! regulation of ATPase activity GO:0043462 21 15 0,000 7,447E-03 0,01389955 ! dopamine metabolic process GO:0042417 35 15 0,000 7,447E-03 0,01388877 ! heme biosynthetic process GO:0006783 29 15 0,000 7,447E-03 0,01387801 ! cell killing GO:0001906 29 15 0,000 7,447E-03 0,01386727 ! lymphocyte homeostasis GO:0002260 30 15 0,000 7,447E-03 0,01385655 ! detection of bacterium GO:0016045 18 15 0,000 7,447E-03 0,01384584 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 7,447E-03 0,01383515 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 7,447E-03 0,01382447 ! L-fucose metabolic process GO:0042354 30 15 0,000 7,447E-03 0,01381381 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 7,447E-03 0,01380317 ! peptide hormone processing GO:0016486 23 15 0,000 7,447E-03 0,01379254 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 7,941E-03 0,01469732 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 7,941E-03 0,01468602 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 7,941E-03 0,01467474 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 7,941E-03 0,01466348 ! dicarboxylic acid transport GO:0006835 38 16 0,000 7,941E-03 0,01465223 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 7,941E-03 0,014641 ! bone remodeling GO:0046849 27 16 0,000 7,941E-03 0,01462979 ! filopodium assembly GO:0046847 32 16 0,000 7,941E-03 0,0146186 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 7,941E-03 0,01460742 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 7,941E-03 0,01459627 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 7,941E-03 0,01458512 ! positive regulation of ion transport GO:0043270 21 16 0,000 7,941E-03 0,014574 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 7,941E-03 0,01456289 ! startle response GO:0001964 28 16 0,000 7,941E-03 0,0145518 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 7,941E-03 0,01454072 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 7,941E-03 0,01452967 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 7,941E-03 0,01451863 ! activation of MAPKK activity GO:0000186 35 16 0,000 7,941E-03 0,0145076 ! regulation of defense response to virus GO:0050688 27 16 0,000 7,941E-03 0,01449659 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 7,941E-03 0,0144856 ! protein polyubiquitination GO:0000209 34 16 0,000 7,941E-03 0,01447463 ! glutamate metabolic process GO:0006536 22 16 0,000 7,941E-03 0,01446367 ! complement activation, alternative pathway GO:0006957 18 16 0,000 7,941E-03 0,01445273 ! response to osmotic stress GO:0006970 25 16 0,000 7,941E-03 0,01444181 ! lysosomal transport GO:0007041 26 16 0,000 7,941E-03 0,0144309 ! fructose metabolic process GO:0006000 25 16 0,000 7,941E-03 0,01442001 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 7,941E-03 0,01440913 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 7,941E-03 0,01439828 ! intermediate filament-based process GO:0045103 32 16 0,000 7,941E-03 0,01438743 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 7,941E-03 0,01437661 ! negative regulation of immune response GO:0050777 35 16 0,000 7,941E-03 0,0143658 ! axon cargo transport GO:0008088 43 16 0,000 7,941E-03 0,014355 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 7,941E-03 0,01434423 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 7,941E-03 0,01433347 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 7,941E-03 0,01432272 ! DNA replication initiation GO:0006270 27 16 0,000 7,941E-03 0,01431199 ! neuron recognition GO:0008038 35 16 0,000 7,941E-03 0,01430128 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 7,941E-03 0,01429058 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 7,941E-03 0,0142799 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 7,941E-03 0,01426924 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 7,941E-03 0,01425859 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 7,941E-03 0,01424796 ! sphingolipid catabolic process GO:0030149 27 16 0,000 7,941E-03 0,01423734 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 7,941E-03 0,01422674 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 7,941E-03 0,01421615 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 7,941E-03 0,01420558 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 7,941E-03 0,01419503 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 7,941E-03 0,01418449 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 7,941E-03 0,01417397 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 7,941E-03 0,01416346 ! defense response to virus GO:0051607 37 16 0,000 7,941E-03 0,01415297 ! positive regulation of cell killing GO:0031343 32 17 0,000 8,436E-03 0,01502291 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 8,436E-03 0,0150118 ! metencephalon development GO:0022037 30 17 0,000 8,436E-03 0,0150007 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 8,436E-03 0,01498963 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 8,436E-03 0,01497856 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 8,436E-03 0,01496752 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 8,436E-03 0,01495649 ! signal complex assembly GO:0007172 41 17 0,000 8,436E-03 0,01494547 ! endothelial cell migration GO:0043542 28 17 0,000 8,436E-03 0,01493448 ! inositol metabolic process GO:0006020 28 17 0,000 8,436E-03 0,0149235 ! gene silencing by RNA GO:0031047 36 17 0,000 8,436E-03 0,01491253 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 8,436E-03 0,01490158 ! glial cell development GO:0021782 27 17 0,000 8,436E-03 0,01489065 ! limbic system development GO:0021761 36 17 0,000 8,436E-03 0,01487973 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 8,436E-03 0,01486883 ! adult walking behavior GO:0007628 33 17 0,000 8,436E-03 0,01485795 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 8,436E-03 0,01484708 ! heart looping GO:0001947 30 17 0,000 8,436E-03 0,01483622 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 8,436E-03 0,01482539 ! regulation of viral genome replication GO:0045069 28 17 0,000 8,436E-03 0,01481456 ! myoblast differentiation GO:0045445 45 17 0,000 8,436E-03 0,01480376 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 8,436E-03 0,01479297 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 8,436E-03 0,01478219 ! regulation of survival gene product expression GO:0045884 33 17 0,000 8,436E-03 0,01477144 ! cardiac muscle tissue development GO:0048738 31 17 0,000 8,436E-03 0,01476069 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 8,436E-03 0,01474997 ! glycine metabolic process GO:0006544 28 17 0,000 8,436E-03 0,01473925 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 8,436E-03 0,01472856 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 8,436E-03 0,01471788 ! NAD metabolic process GO:0019674 29 17 0,000 8,436E-03 0,01470721 ! membrane budding GO:0006900 37 17 0,000 8,436E-03 0,01469656 ! DNA integration GO:0015074 29 17 0,000 8,436E-03 0,01468593 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 8,436E-03 0,01467531 ! regulation of protein binding GO:0043393 33 17 0,000 8,436E-03 0,01466471 ! nucleobase metabolic process GO:0009112 37 17 0,000 8,436E-03 0,01465412 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 8,436E-03 0,01464355 ! DNA unwinding during replication GO:0006268 27 17 0,000 8,436E-03 0,01463299 ! genitalia development GO:0048806 30 17 0,000 8,436E-03 0,01462244 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 8,436E-03 0,01461192 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 8,436E-03 0,01460141 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 8,436E-03 0,01459091 ! neutrophil chemotaxis GO:0030593 27 17 0,000 8,436E-03 0,01458043 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 8,436E-03 0,01456996 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 8,436E-03 0,01455951 ! steroid catabolic process GO:0006706 31 17 0,000 8,436E-03 0,01454907 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 8,436E-03 0,01453865 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 8,436E-03 0,01452824 ! gas transport GO:0015669 25 17 0,000 8,436E-03 0,01451785 ! organic cation transport GO:0015695 31 17 0,000 8,436E-03 0,01450747 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 8,436E-03 0,01449711 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 8,436E-03 0,01448676 ! RNA 3'-end processing GO:0031123 34 17 0,000 8,436E-03 0,01447643 ! microspike assembly GO:0030035 36 17 0,000 8,436E-03 0,01446611 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 8,436E-03 0,01445581 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 8,93E-03 0,0152917 ! neuron maturation GO:0042551 42 18 0,000 8,93E-03 0,01528083 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 8,93E-03 0,01526997 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 8,93E-03 0,01525912 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 8,93E-03 0,01524829 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 8,93E-03 0,01523748 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 8,93E-03 0,01522668 ! aminoglycan catabolic process GO:0006026 22 18 0,000 8,93E-03 0,01521589 ! memory GO:0007613 31 18 0,000 8,93E-03 0,01520513 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 8,93E-03 0,01519437 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 8,93E-03 0,01518363 ! patterning of blood vessels GO:0001569 39 18 0,000 8,93E-03 0,01517291 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 8,93E-03 0,0151622 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 8,93E-03 0,01515151 ! positive regulation of proteolysis GO:0045862 31 18 0,000 8,93E-03 0,01514083 ! epidermis morphogenesis GO:0048730 40 18 0,000 8,93E-03 0,01513017 ! glutamine metabolic process GO:0006541 29 18 0,000 8,93E-03 0,01511952 ! response to retinoic acid GO:0032526 26 18 0,000 8,93E-03 0,01510889 ! cell-substrate junction assembly GO:0007044 54 18 0,000 8,93E-03 0,01509827 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 8,93E-03 0,01508767 ! response to fungus GO:0009620 21 18 0,000 8,93E-03 0,01507708 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 8,93E-03 0,01506651 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 8,93E-03 0,01505595 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 8,93E-03 0,01504541 ! long-chain fatty acid transport GO:0015909 31 18 0,000 8,93E-03 0,01503488 ! peptide biosynthetic process GO:0043043 24 18 0,000 8,93E-03 0,01502437 ! vitamin transport GO:0051180 27 18 0,000 8,93E-03 0,01501387 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 8,93E-03 0,01500338 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 8,93E-03 0,01499291 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 8,93E-03 0,01498246 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 8,93E-03 0,01497202 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 8,93E-03 0,01496159 ! aromatic compound catabolic process GO:0019439 27 18 0,000 8,93E-03 0,01495118 ! nerve development GO:0021675 28 18 0,000 8,93E-03 0,01494078 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 8,93E-03 0,0149304 ! protein secretion GO:0009306 39 19 0,000 9,424E-03 0,01574526 ! positive regulation of translation GO:0045727 30 19 0,000 9,424E-03 0,01573434 ! negative regulation of defense response GO:0031348 25 19 0,000 9,424E-03 0,01572342 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 9,424E-03 0,01571253 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 9,424E-03 0,01570165 ! skin development GO:0043588 36 19 0,000 9,424E-03 0,01569078 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 9,424E-03 0,01567993 ! lipid phosphorylation GO:0046834 35 19 0,000 9,424E-03 0,01566909 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 9,424E-03 0,01565827 ! forelimb morphogenesis GO:0035136 32 19 0,000 9,424E-03 0,01564747 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 9,424E-03 0,01563667 ! bile acid metabolic process GO:0008206 29 19 0,000 9,424E-03 0,0156259 ! mitotic chromosome condensation GO:0007076 34 19 0,000 9,424E-03 0,01561514 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 9,424E-03 0,01560439 ! cerebral cortex development GO:0021987 36 19 0,000 9,424E-03 0,01559366 ! pigmentation during development GO:0048066 41 19 0,000 9,424E-03 0,01558294 ! response to vitamin A GO:0033189 27 19 0,000 9,424E-03 0,01557224 ! heme metabolic process GO:0042168 36 19 0,000 9,424E-03 0,01556155 ! actin filament bundle formation GO:0051017 42 19 0,000 9,424E-03 0,01555088 ! neuromuscular junction development GO:0007528 34 19 0,000 9,424E-03 0,01554022 ! response to lipopolysaccharide GO:0032496 30 19 0,000 9,424E-03 0,01552957 ! plasma membrane fusion GO:0045026 28 19 0,000 9,424E-03 0,01551894 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 9,424E-03 0,01550833 ! peptide cross-linking GO:0018149 37 19 0,000 9,424E-03 0,01549773 ! protein export from nucleus GO:0006611 36 19 0,000 9,424E-03 0,01548714 ! heart process GO:0003015 30 19 0,000 9,424E-03 0,01547657 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 9,424E-03 0,01546602 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 9,424E-03 0,01545547 ! visual learning GO:0008542 36 19 0,000 9,424E-03 0,01544494 ! cellular pigmentation GO:0033059 36 19 0,000 9,424E-03 0,01543443 ! G1 phase GO:0051318 40 19 0,000 9,424E-03 0,01542393 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 9,424E-03 0,01541345 ! cell-cell junction organization GO:0045216 35 19 0,000 9,424E-03 0,01540297 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 9,424E-03 0,01539252 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 9,424E-03 0,01538207 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 9,424E-03 0,01537165 ! proximal/distal pattern formation GO:0009954 32 19 0,000 9,424E-03 0,01536123 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 9,424E-03 0,01535083 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 9,424E-03 0,01534045 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 9,424E-03 0,01533007 ! cilium assembly GO:0042384 37 19 0,000 9,424E-03 0,01531972 ! peptide hormone secretion GO:0030072 31 19 0,000 9,424E-03 0,01530937 ! protein import into nucleus, docking GO:0000059 41 20 0,000 9,917E-03 0,01610051 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 9,917E-03 0,01608966 ! positive regulation of ossification GO:0045778 47 20 0,000 9,917E-03 0,01607882 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 9,917E-03 0,01606799 ! protein amino acid deacetylation GO:0006476 29 20 0,000 9,917E-03 0,01605717 ! protein amino acid acetylation GO:0006473 39 20 0,000 9,917E-03 0,01604638 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 9,917E-03 0,01603559 ! cAMP metabolic process GO:0046058 36 20 0,000 9,917E-03 0,01602482 ! response to vitamin GO:0033273 31 20 0,000 9,917E-03 0,01601407 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 9,917E-03 0,01600333 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 9,917E-03 0,0159926 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 9,917E-03 0,01598189 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 9,917E-03 0,01597119 ! response to alkaloid GO:0043279 38 20 0,000 9,917E-03 0,01596051 ! retinoid metabolic process GO:0001523 32 20 0,000 9,917E-03 0,01594984 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 9,917E-03 0,01593919 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 9,917E-03 0,01592855 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 9,917E-03 0,01591792 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 9,917E-03 0,01590731 ! DNA duplex unwinding GO:0032508 31 20 0,000 9,917E-03 0,01589671 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 9,917E-03 0,01588613 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 9,917E-03 0,01587556 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 9,917E-03 0,015865 ! D-ribose metabolic process GO:0006014 29 20 0,000 9,917E-03 0,01585446 ! body fluid secretion GO:0007589 31 20 0,000 9,917E-03 0,01584393 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 9,917E-03 0,01583342 ! peptide secretion GO:0002790 35 20 0,000 9,917E-03 0,01582292 ! stem cell differentiation GO:0048863 53 20 0,000 9,917E-03 0,01581243 ! behavioral interaction between organisms GO:0051705 38 20 0,000 9,917E-03 0,01580196 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 9,917E-03 0,0157915 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 9,917E-03 0,01578106 ! sensory perception of pain GO:0019233 30 20 0,000 9,917E-03 0,01577063 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 9,917E-03 0,01576021 ! diencephalon development GO:0021536 34 20 0,000 9,917E-03 0,01574981 ! protein localization in mitochondrion GO:0070585 32 20 0,000 9,917E-03 0,01573942 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 9,917E-03 0,01572905 ! detection of chemical stimulus GO:0009593 37 20 0,000 9,917E-03 0,01571868 ! peptidyl-serine modification GO:0018209 43 20 0,000 9,917E-03 0,01570834 ! positive regulation of neurological system process GO:0031646 32 20 0,000 9,917E-03 0,015698 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 9,917E-03 0,01568768 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 9,917E-03 0,01567737 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 9,917E-03 0,01566708 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 9,917E-03 0,0156568 ! regulation of glucose import GO:0046324 29 20 0,000 9,917E-03 0,01564653 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 9,917E-03 0,01563628 ! actin filament-based movement GO:0030048 43 20 0,000 9,917E-03 0,01562604 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 9,917E-03 0,01561581 ! negative regulation of T cell activation GO:0050868 40 20 0,000 9,917E-03 0,0156056 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 9,917E-03 0,0155954 ! negative regulation of translation GO:0017148 29 20 0,000 9,917E-03 0,01558521 ! negative regulation of coagulation GO:0050819 29 20 0,000 9,917E-03 0,01557504 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 9,917E-03 0,01556488 ! regulation of cell killing GO:0031341 42 21 0,000 0,01041072 0,01632868 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,01041072 0,01631804 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,01041072 0,01630742 ! hormone secretion GO:0046879 38 21 0,000 0,01041072 0,01629681 ! glycerol metabolic process GO:0006071 34 21 0,000 0,01041072 0,01628621 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,01041072 0,01627563 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,01041072 0,01626506 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,01041072 0,01625451 ! axis specification GO:0009798 38 21 0,000 0,01041072 0,01624396 ! ovarian follicle development GO:0001541 35 21 0,000 0,01041072 0,01623344 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,01041072 0,01622292 ! smooth muscle contraction GO:0006939 46 21 0,000 0,01041072 0,01621242 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,01041072 0,01620194 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,01041072 0,01619146 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,01041072 0,016181 ! cell aging GO:0007569 44 21 0,000 0,01041072 0,01617056 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,01041072 0,01616012 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,01041072 0,01614971 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,01041072 0,0161393 ! cytolysis GO:0019835 24 21 0,000 0,01041072 0,01612891 ! vasodilation GO:0042311 39 21 0,000 0,01041072 0,01611853 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,01041072 0,01610816 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,01041072 0,01609781 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,01041072 0,01608747 ! oogenesis GO:0048477 36 21 0,000 0,01041072 0,01607715 ! DNA modification GO:0006304 34 21 0,000 0,01041072 0,01606683 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,01041072 0,01605653 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,01041072 0,01604625 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,01041072 0,01603597 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,01041072 0,01602572 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,01041072 0,01601547 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,01041072 0,01600523 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,01041072 0,01599501 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,01041072 0,01598481 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,01041072 0,01597461 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,01041072 0,01596443 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,01041072 0,01595426 ! collagen catabolic process GO:0030574 28 21 0,000 0,01041072 0,01594411 ! sperm-egg recognition GO:0035036 21 21 0,000 0,01041072 0,01593396 ! gut development GO:0048565 39 21 0,000 0,01041072 0,01592384 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,01090394 0,01666764 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,01090394 0,01665706 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,01090394 0,01664649 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,01090394 0,01663594 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,01090394 0,01662539 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,01090394 0,01661486 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,01090394 0,01660435 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,01090394 0,01659385 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,01090394 0,01658336 ! regeneration GO:0031099 41 22 0,000 0,01090394 0,01657288 ! keratinization GO:0031424 28 22 0,000 0,01090394 0,01656242 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,01090394 0,01655197 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,01090394 0,01654153 ! sensory perception of taste GO:0050909 28 22 0,000 0,01090394 0,01653111 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,01090394 0,0165207 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,01090394 0,0165103 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,01090394 0,01649992 ! vacuolar transport GO:0007034 36 22 0,000 0,01090394 0,01648955 ! lysosome organization GO:0007040 41 22 0,000 0,01090394 0,01647919 ! central nervous system neuron development GO:0021954 46 22 0,000 0,01090394 0,01646885 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,01090394 0,01645851 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,01090394 0,0164482 ! fucose metabolic process GO:0006004 39 22 0,000 0,01090394 0,01643789 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,01090394 0,0164276 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,01090394 0,01641732 ! ureteric bud development GO:0001657 43 22 0,000 0,01090394 0,01640705 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,01090394 0,01639679 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,01090394 0,01638655 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,01090394 0,01637632 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,01090394 0,01636611 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,01090394 0,0163559 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,01090394 0,01634571 ! sarcomere organization GO:0045214 30 22 0,000 0,01090394 0,01633554 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,01090394 0,01632537 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,01090394 0,01631522 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,01090394 0,01630508 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,01090394 0,01629495 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,01090394 0,01628484 ! protein stabilization GO:0050821 39 22 0,000 0,01090394 0,01627473 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,01139692 0,017 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,01139692 0,01698947 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,01139692 0,01697895 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,01139692 0,01696844 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,01139692 0,01695795 ! gluconeogenesis GO:0006094 33 23 0,000 0,01139692 0,01694746 ! viral genome replication GO:0019079 41 23 0,000 0,01139692 0,016937 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,01139692 0,01692654 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,01139692 0,0169161 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,01139692 0,01690567 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,01139692 0,01689525 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,01139692 0,01688485 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,01139692 0,01687446 ! visual behavior GO:0007632 42 23 0,000 0,01139692 0,01686408 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,01139692 0,01685372 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,01139692 0,01684336 ! response to ethanol GO:0045471 46 23 0,000 0,01139692 0,01683302 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,01139692 0,0168227 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,01139692 0,01681238 ! peroxisome organization GO:0007031 37 23 0,000 0,01139692 0,01680208 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,01139692 0,01679179 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,01139692 0,01678152 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,01139692 0,01677125 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,01139692 0,016761 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,01139692 0,01675076 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,01139692 0,01674054 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,01139692 0,01673032 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,01139692 0,01672012 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,01139692 0,01670993 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,01139692 0,01669975 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,01139692 0,01668959 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,01139692 0,01667944 ! fatty acid transport GO:0015908 44 23 0,000 0,01139692 0,0166693 ! platelet activation GO:0030168 37 23 0,000 0,01139692 0,01665917 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,01139692 0,01664906 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,01139692 0,01663895 ! hormone transport GO:0009914 40 23 0,000 0,01139692 0,01662886 ! cell-cell recognition GO:0009988 25 23 0,000 0,01139692 0,01661879 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,01139692 0,01660872 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,01139692 0,01659867 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,01139692 0,01658863 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,01139692 0,0165786 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,01139692 0,01656858 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,01188968 0,0172745 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,01188968 0,01726408 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,01188968 0,01725366 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,01188968 0,01724326 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,01188968 0,01723287 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,01188968 0,0172225 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,01188968 0,01721214 ! vesicle docking GO:0048278 47 24 0,000 0,01188968 0,01720179 ! spinal cord development GO:0021510 47 24 0,000 0,01188968 0,01719145 ! vacuole organization GO:0007033 43 24 0,000 0,01188968 0,01718112 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,01188968 0,01717081 ! digestive system process GO:0022600 39 24 0,000 0,01188968 0,01716051 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,01188968 0,01715022 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,01188968 0,01713995 ! regulation of behavior GO:0050795 43 24 0,000 0,01188968 0,01712968 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,01188968 0,01711943 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,01188968 0,01710919 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,01188968 0,01709897 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,01188968 0,01708875 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,01188968 0,01707855 ! membrane depolarization GO:0051899 39 24 0,000 0,01188968 0,01706836 ! pallium development GO:0021543 49 24 0,000 0,01188968 0,01705818 ! pentose metabolic process GO:0019321 35 24 0,000 0,01188968 0,01704802 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,01188968 0,01703786 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,01188968 0,01702772 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,01188968 0,01701759 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,01188968 0,01700747 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,01188968 0,01699737 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,01188968 0,01698728 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,01188968 0,01697719 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,01188968 0,01696712 ! regulation of amine transport GO:0051952 40 24 0,000 0,01188968 0,01695707 ! protein tetramerization GO:0051262 52 24 0,000 0,01188968 0,01694702 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,01238221 0,0176386 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,01238221 0,01762816 ! myelination GO:0042552 45 25 0,000 0,01238221 0,01761774 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,01238221 0,01760733 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,01238221 0,01759693 ! phototransduction GO:0007602 33 25 0,000 0,01238221 0,01758654 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,01238221 0,01757616 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,01238221 0,0175658 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,01238221 0,01755545 ! sperm motility GO:0030317 31 25 0,000 0,01238221 0,01754511 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,01238221 0,01753478 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,01238221 0,01752447 ! receptor metabolic process GO:0043112 46 25 0,000 0,01238221 0,01751417 ! chromosome condensation GO:0030261 45 25 0,000 0,01238221 0,01750388 ! response to starvation GO:0042594 42 25 0,000 0,01238221 0,0174936 ! osteoblast differentiation GO:0001649 60 25 0,000 0,01238221 0,01748333 ! neural crest cell development GO:0014032 54 25 0,000 0,01238221 0,01747308 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,01238221 0,01746283 ! negative regulation of cell development GO:0010721 73 25 0,000 0,01238221 0,0174526 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,01238221 0,01744239 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,01238221 0,01743218 ! interaction with host GO:0051701 62 25 0,000 0,01238221 0,01742199 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,01238221 0,0174118 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,01238221 0,01740163 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,01238221 0,01739147 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,01238221 0,01738133 ! immunoglobulin production GO:0002377 55 25 0,000 0,01238221 0,01737119 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,01238221 0,01736107 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,01238221 0,01735096 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,01238221 0,01734086 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,01238221 0,01733077 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,01238221 0,0173207 ! telomere organization GO:0032200 43 25 0,000 0,01238221 0,01731063 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,01238221 0,01730058 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,01238221 0,01729054 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,01287451 0,01796756 ! embryonic pattern specification GO:0009880 44 26 0,000 0,01287451 0,01795714 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,01287451 0,01794674 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,01287451 0,01793634 ! initiation of viral infection GO:0019059 57 26 0,000 0,01287451 0,01792596 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,01287451 0,0179156 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,01287451 0,01790524 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,01287451 0,0178949 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,01287451 0,01788457 ! molting cycle process GO:0022404 50 26 0,000 0,01287451 0,01787425 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,01287451 0,01786394 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,01287451 0,01785364 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,01287451 0,01784336 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,01287451 0,01783308 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,01287451 0,01782282 GO:0051297|centrosome organization, ! insulin receptor signaling pathway GO:0008286 64 26 0,000 0,01287451 0,01781257 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,01287451 0,01780234 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,01287451 0,01779211 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,01287451 0,0177819 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,01287451 0,0177717 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,01287451 0,01776151 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,01287451 0,01775133 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,01287451 0,01774116 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,01287451 0,01773101 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,01287451 0,01772086 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,01287451 0,01771073 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,01287451 0,01770061 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,01287451 0,0176905 ! blastocyst development GO:0001824 49 26 0,000 0,01287451 0,0176804 ! leukocyte proliferation GO:0070661 52 26 0,000 0,01287451 0,01767032 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,01287451 0,01766024 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,01287451 0,01765018 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,01336658 0,01831434 ! neuron fate commitment GO:0048663 48 27 0,000 0,01336658 0,01830392 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,01336658 0,01829351 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,01336658 0,01828311 ! iron ion transport GO:0006826 59 27 0,000 0,01336658 0,01827272 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,01336658 0,01826234 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,01336658 0,01825198 ! protein amino acid acylation GO:0043543 55 27 0,000 0,01336658 0,01824163 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,01336658 0,01823129 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,01336658 0,01822096 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,01336658 0,01821064 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,01336658 0,01820033 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,01336658 0,01819004 ! autophagy GO:0006914 41 27 0,000 0,01336658 0,01817976 ! male gonad development GO:0008584 44 27 0,000 0,01336658 0,01816948 ! response to toxin GO:0009636 47 27 0,000 0,01336658 0,01815923 ! primary neural tube formation GO:0014020 51 27 0,000 0,01336658 0,01814898 ! base-excision repair GO:0006284 41 27 0,000 0,01336658 0,01813874 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,01336658 0,01812852 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,01336658 0,0181183 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,01336658 0,0181081 ! glutathione metabolic process GO:0006749 39 27 0,000 0,01336658 0,01809791 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,01336658 0,01808773 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,01336658 0,01807756 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,01336658 0,01806741 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,01336658 0,01805726 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,01385842 0,0187112 ! circadian rhythm GO:0007623 50 28 0,000 0,01385842 0,01870071 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,01385842 0,01869022 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,01385842 0,01867975 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,01385842 0,01866929 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,01385842 0,01865885 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,01385842 0,01864841 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,01385842 0,01863799 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,01385842 0,01862757 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,01385842 0,01861717 ! synaptogenesis GO:0007416 42 28 0,000 0,01385842 0,01860678 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,01385842 0,01859641 ! lipid oxidation GO:0034440 43 28 0,000 0,01385842 0,01858604 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,01385842 0,01857569 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,01385842 0,01856534 ! translational initiation GO:0006413 65 29 0,000 0,01435003 0,01921323 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,01435003 0,01920255 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,01435003 0,01919187 ! regulation of pH GO:0006885 43 29 0,000 0,01435003 0,01918121 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,01435003 0,01917056 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,01435003 0,01915992 ! catechol metabolic process GO:0009712 54 29 0,000 0,01435003 0,01914929 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,01435003 0,01913868 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,01435003 0,01912808 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,01435003 0,01911748 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,01435003 0,0191069 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,01435003 0,01909634 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,01435003 0,01908578 ! cell fate determination GO:0001709 60 29 0,000 0,01435003 0,01907524 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,01435003 0,0190647 ! detection of light stimulus GO:0009583 38 29 0,000 0,01435003 0,01905418 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 0,01435003 0,01904367 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,01435003 0,01903317 ! tissue homeostasis GO:0001894 48 29 0,000 0,01435003 0,01902269 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,01435003 0,01901221 ! phenol metabolic process GO:0018958 55 30 0,000 0,01484142 0,01965242 ! zinc ion transport GO:0006829 45 30 0,000 0,01484142 0,01964161 ! membrane docking GO:0022406 61 30 0,000 0,01484142 0,01963081 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,01484142 0,01962003 ! cell junction assembly GO:0034329 78 30 0,000 0,01484142 0,01960925 ! regulation of innate immune response GO:0045088 51 30 0,000 0,01484142 0,01959849 ! acute-phase response GO:0006953 49 30 0,000 0,01484142 0,01958774 ! myofibril assembly GO:0030239 47 30 0,000 0,01484142 0,019577 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,01484142 0,01956627 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,01484142 0,01955556 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,01484142 0,01954485 ! phospholipid transport GO:0015914 51 30 0,000 0,01484142 0,01953416 ! ensheathment of neurons GO:0007272 57 30 0,000 0,01484142 0,01952348 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,01484142 0,01951281 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,01484142 0,01950216 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,01484142 0,01949151 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,01484142 0,01948088 ! eye morphogenesis GO:0048592 60 30 0,000 0,01484142 0,01947025 ! regulation of B cell activation GO:0050864 50 30 0,000 0,01484142 0,01945964 ! response to heat GO:0009408 50 30 0,000 0,01484142 0,01944904 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,01533257 0,02008174 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,01533257 0,02007082 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,01533257 0,0200599 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,01533257 0,020049 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,01533257 0,02003811 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,01533257 0,02002723 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,01533257 0,02001637 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,01533257 0,02000551 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,01533257 0,01999467 ! ovulation cycle process GO:0022602 49 31 0,000 0,01533257 0,01998384 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,01533257 0,01997302 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,01533257 0,01996221 ! peptide transport GO:0015833 55 31 0,000 0,01533257 0,01995141 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,01533257 0,01994063 ! iron ion homeostasis GO:0055072 54 31 0,000 0,01533257 0,01992986 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,01533257 0,0199191 ! mesoderm formation GO:0001707 69 31 0,000 0,01533257 0,01990835 ! natural killer cell activation GO:0030101 45 31 0,000 0,01533257 0,01989761 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,01533257 0,01988688 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,01533257 0,01987617 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,01533257 0,01986546 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,01533257 0,01985477 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,01533257 0,01984409 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,0158235 0,02046846 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,0158235 0,02045746 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,0158235 0,02044647 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,0158235 0,0204355 ! cholesterol transport GO:0030301 56 32 0,000 0,0158235 0,02042454 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,0158235 0,02041358 ! spliceosome assembly GO:0000245 67 32 0,000 0,0158235 0,02040264 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,0158235 0,02039172 ! metanephros development GO:0001656 74 32 0,000 0,0158235 0,0203808 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,0158235 0,0203699 ! response to ionizing radiation GO:0010212 65 32 0,000 0,0158235 0,020359 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,0158235 0,02034812 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,0158235 0,02033725 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,0158235 0,02032639 ! muscle cell development GO:0055001 49 32 0,000 0,0158235 0,02031555 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,0158235 0,02030471 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,0158235 0,02029389 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,0158235 0,02028308 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,0158235 0,02027228 ! ovulation cycle GO:0042698 51 32 0,000 0,0158235 0,02026149 ! peripheral nervous system development GO:0007422 64 32 0,000 0,0158235 0,02025071 ! BMP signaling pathway GO:0030509 64 32 0,000 0,0158235 0,02023994 ! hindbrain development GO:0030902 61 32 0,000 0,0158235 0,02022919 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,0158235 0,02021845 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,0158235 0,02020771 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,0158235 0,02019699 ! gene silencing GO:0016458 65 32 0,000 0,0158235 0,02018629 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,01631419 0,02080125 ! post-embryonic development GO:0009791 69 33 0,000 0,01631419 0,02079023 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,01631419 0,02077922 ! protein targeting to membrane GO:0006612 68 33 0,000 0,01631419 0,02076823 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,01631419 0,02075725 ! ceramide metabolic process GO:0006672 64 33 0,000 0,01631419 0,02074628 ! formation of primary germ layer GO:0001704 72 33 0,000 0,01631419 0,02073532 ! cell fate specification GO:0001708 52 33 0,000 0,01631419 0,02072437 ! sterol transport GO:0015918 57 33 0,000 0,01631419 0,02071343 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,01631419 0,02070251 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,01631419 0,02069159 ! adult locomotory behavior GO:0008344 59 33 0,000 0,01631419 0,02068069 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,01631419 0,0206698 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,01631419 0,02065892 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,01680466 0,02126882 ! glial cell differentiation GO:0010001 63 34 0,000 0,01680466 0,02125764 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,01680466 0,02124647 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,01680466 0,02123531 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,01680466 0,02122416 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,01680466 0,02121302 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,01680466 0,0212019 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,01680466 0,02119079 ! mismatch repair GO:0006298 46 34 0,000 0,01680466 0,02117969 ! spermatid development GO:0007286 63 34 0,000 0,01680466 0,0211686 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,01680466 0,02115752 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,01680466 0,02114646 ! placenta development GO:0001890 53 34 0,000 0,01680466 0,0211354 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,01680466 0,02112436 ! regulation of muscle development GO:0048634 70 35 0,000 0,01729491 0,02172927 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,01729491 0,02171792 ! negative regulation of secretion GO:0051048 63 35 0,000 0,01729491 0,0217066 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,01729491 0,02169528 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,01729491 0,02168397 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,01729491 0,02167268 ! odontogenesis GO:0042476 66 35 0,000 0,01729491 0,0216614 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,01729491 0,02165013 ! female gonad development GO:0008585 58 35 0,000 0,01729491 0,02163887 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,01729491 0,02162762 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,01729491 0,02161639 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,01729491 0,02160516 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,01729491 0,02159395 ! cytokine production GO:0001816 59 35 0,000 0,01729491 0,02158275 ! neural tube formation GO:0001841 67 35 0,000 0,01729491 0,02157156 ! vesicle localization GO:0051648 64 35 0,000 0,01729491 0,02156039 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,01778492 0,02215977 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,01778492 0,0221483 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,01778492 0,02213684 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,01778492 0,0221254 ! cell junction organization GO:0034330 86 36 0,000 0,01778492 0,02211396 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,01778492 0,02210254 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,01778492 0,02209113 ! positive regulation of cell development GO:0010720 80 36 0,000 0,01778492 0,02207973 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,01778492 0,02206834 ! regulation of proteolysis GO:0030162 72 36 0,000 0,01778492 0,02205697 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,01778492 0,0220456 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,01778492 0,02203425 ! aerobic respiration GO:0009060 55 36 0,000 0,01778492 0,02202291 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,01778492 0,02201158 ! embryonic organ development GO:0048568 57 36 0,000 0,01778492 0,02200026 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,01778492 0,02198896 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,01778492 0,02197767 ! RNA export from nucleus GO:0006405 56 37 0,000 0,0182747 0,02257132 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,0182747 0,02255974 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,0182747 0,02254817 ! sister chromatid segregation GO:0000819 58 37 0,000 0,0182747 0,02253662 ! actomyosin structure organization GO:0031032 62 37 0,000 0,0182747 0,02252507 ! organic anion transport GO:0015711 68 37 0,000 0,0182747 0,02251354 ! tissue remodeling GO:0048771 76 37 0,000 0,0182747 0,02250202 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,0182747 0,02249051 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,0182747 0,02247901 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,0182747 0,02246752 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,0182747 0,02245605 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,0182747 0,02244458 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,0182747 0,02243313 ! glycogen metabolic process GO:0005977 61 37 0,000 0,0182747 0,02242169 ! pigment metabolic process GO:0042440 80 37 0,000 0,0182747 0,02241026 ! spermatid differentiation GO:0048515 66 37 0,000 0,0182747 0,02239885 ! cellular response to insulin stimulus GO:0032869 82 37 0,000 0,0182747 0,02238744 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,01876426 0,02297548 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,01876426 0,02296379 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,01876426 0,02295212 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,01876426 0,02294045 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,01876426 0,0229288 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,01876426 0,02291716 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,01876426 0,02290554 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,01876426 0,02289392 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,01876426 0,02288232 ! lipid homeostasis GO:0055088 67 38 0,000 0,01876426 0,02287073 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,01876426 0,02285915 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,01876426 0,02284758 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,01876426 0,02283602 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,01876426 0,02282448 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,01876426 0,02281294 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,01876426 0,02280142 ! glucan metabolic process GO:0044042 62 38 0,000 0,01876426 0,02278991 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,01925359 0,02337242 ! mammary gland development GO:0030879 86 39 0,000 0,01925359 0,02336063 ! learning GO:0007612 77 39 0,000 0,01925359 0,02334886 ! ear morphogenesis GO:0042471 60 39 0,000 0,01925359 0,0233371 ! organic ether metabolic process GO:0018904 55 39 0,000 0,01925359 0,02332535 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,01925359 0,02331361 ! segmentation GO:0035282 67 39 0,000 0,01925359 0,02330188 ! ion transmembrane transport GO:0034220 66 39 0,000 0,01925359 0,02329017 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,01925359 0,02327846 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,01925359 0,02326677 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,01925359 0,02325509 ! RNA modification GO:0009451 57 39 0,000 0,01925359 0,02324342 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,01925359 0,02323176 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,01974269 0,02380998 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,01974269 0,02379805 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,01974269 0,02378614 ! feeding behavior GO:0007631 59 40 0,000 0,01974269 0,02377423 ! negative regulation of binding GO:0051100 72 40 0,000 0,01974269 0,02376234 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,01974269 0,02375046 ! mesenchymal cell development GO:0014031 87 40 0,000 0,01974269 0,02373859 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,01974269 0,02372673 ! maintenance of protein location GO:0045185 91 40 0,000 0,01974269 0,02371489 ! cytokinesis GO:0000910 72 40 0,000 0,01974269 0,02370305 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,02023157 0,02427788 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,02023157 0,02426578 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,02023157 0,02425369 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,02023157 0,02424161 ! gliogenesis GO:0042063 88 41 0,000 0,02023157 0,02422954 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,02023157 0,02421749 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,02023157 0,02420544 ! T cell differentiation GO:0030217 81 41 0,000 0,02023157 0,02419341 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,02023157 0,02418139 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,02023157 0,02416939 ! female gamete generation GO:0007292 61 41 0,000 0,02023157 0,02415739 ! polyol metabolic process GO:0019751 66 41 0,000 0,02023157 0,02414541 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,02023157 0,02413344 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,02072021 0,02470408 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,02072021 0,02469184 ! regulation of tube size GO:0035150 71 42 0,000 0,02072021 0,02467962 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,02072021 0,02466741 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,02072021 0,02465521 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,02072021 0,02464302 ! regulation of intracellular protein transport GO:0033157 80 42 0,000 0,02072021 0,02463085 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,02072021 0,02461868 ! neuron migration GO:0001764 79 42 0,000 0,02072021 0,02460653 ! regulation of protein secretion GO:0050708 71 42 0,000 0,02072021 0,02459439 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,02072021 0,02458226 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,02120863 0,02514932 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,02120863 0,02513693 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,02120863 0,02512455 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,02120863 0,02511219 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,02120863 0,02509984 ! glucose transport GO:0015758 65 43 0,000 0,02120863 0,0250875 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,02120863 0,02507517 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,02120863 0,02506285 ! neural tube development GO:0021915 77 43 0,000 0,02120863 0,02505055 ! regulation of epithelial cell proliferation GO:0050678 111 43 0,000 0,02120863 0,02503826 ! striated muscle contraction GO:0006941 77 43 0,000 0,02120863 0,02502598 ! phagocytosis GO:0006909 90 43 0,000 0,02120863 0,02501371 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,02120863 0,02500145 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,02169682 0,02556442 ! hexose transport GO:0008645 67 44 0,000 0,02169682 0,02555191 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,02169682 0,02553941 ! male sex differentiation GO:0046661 76 44 0,000 0,02169682 0,02552692 ! double-strand break repair GO:0006302 81 44 0,000 0,02169682 0,02551445 ! biopolymer methylation GO:0043414 84 44 0,000 0,02169682 0,02550198 ! B cell differentiation GO:0030183 107 44 0,000 0,02169682 0,02548953 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,02169682 0,02547709 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,02169682 0,02546466 ! developmental growth GO:0048589 82 44 0,000 0,02169682 0,02545225 ! maintenance of location in cell GO:0051651 97 44 0,000 0,02169682 0,02543984 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,02218479 0,02599932 ! glycolysis GO:0006096 65 45 0,000 0,02218479 0,02598666 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,02218479 0,02597401 ! leukocyte migration GO:0050900 68 45 0,000 0,02218479 0,02596138 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,02218479 0,02594876 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,02218479 0,02593615 ! induction of apoptosis by intracellular signals GO:0008629 93 45 0,000 0,02218479 0,02592355 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,02218479 0,02591097 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,02218479 0,0258984 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,02218479 0,02588584 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,02218479 0,02587329 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,02218479 0,02586075 ! cell growth GO:0016049 84 45 0,000 0,02218479 0,02584823 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,02267252 0,02640372 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 0,000 0,02267252 0,02639095 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,02267252 0,02637819 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,02267252 0,02636544 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,02267252 0,0263527 ! pigmentation GO:0043473 100 46 0,000 0,02267252 0,02633998 ! response to insulin stimulus GO:0032868 95 46 0,000 0,02267252 0,02632726 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,02267252 0,02631456 ! positive regulation of defense response GO:0031349 76 47 0,000 0,02316003 0,02686743 ! endosome transport GO:0016197 108 47 0,000 0,02316003 0,02685448 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,02316003 0,02684154 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,02316003 0,02682862 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,02316003 0,02681571 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,02316003 0,02680281 ! JNK cascade GO:0007254 91 47 0,000 0,02316003 0,02678992 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,02316003 0,02677705 ! methylation GO:0032259 90 47 0,000 0,02316003 0,02676419 ! protein homooligomerization GO:0051260 76 47 0,000 0,02316003 0,02675134 ! mitochondrial transport GO:0006839 82 48 0,000 0,02364732 0,02730108 ! Notch signaling pathway GO:0007219 96 48 0,000 0,02364732 0,02728798 ! cellular component disassembly GO:0022411 86 48 0,000 0,02364732 0,0272749 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,02364732 0,02726183 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,02364732 0,02724878 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,02364732 0,02723573 ! activation of caspase activity GO:0006919 84 48 0,000 0,02364732 0,0272227 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,02364732 0,02720968 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,02364732 0,02719668 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,02364732 0,02718368 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,02364732 0,0271707 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,02413437 0,02771709 ! regulation of action potential GO:0001508 95 49 0,000 0,02413437 0,02770387 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,02413437 0,02769065 ! regulation of ion transport GO:0043269 77 49 0,000 0,02413437 0,02767746 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,02413437 0,02766427 ! peptide metabolic process GO:0006518 76 49 0,000 0,02413437 0,0276511 ! response to temperature stimulus GO:0009266 76 49 0,000 0,02413437 0,02763794 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,02413437 0,02762479 ! endocrine system development GO:0035270 104 49 0,000 0,02413437 0,02761165 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,02413437 0,02759853 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,02413437 0,02758542 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,02413437 0,02757232 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,02413437 0,02755923 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,0246212 0,02810181 ! neuromuscular process GO:0050905 99 50 0,000 0,0246212 0,02808848 ! regulation of ossification GO:0030278 117 50 0,000 0,0246212 0,02807517 ! inner ear development GO:0048839 79 50 0,000 0,0246212 0,02806187 ! histone modification GO:0016570 91 50 0,000 0,0246212 0,02804859 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,0246212 0,02803531 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,0246212 0,02802205 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,0246212 0,0280088 ! positive regulation of binding GO:0051099 78 51 0,000 0,02510781 0,02854886 ! viral infectious cycle GO:0019058 99 51 0,000 0,02510781 0,02853537 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,02510781 0,0285219 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,02510781 0,02850844 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,02510781 0,02849499 ! excretion GO:0007588 83 51 0,000 0,02510781 0,02848156 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,02510781 0,02846813 ! chromatin remodeling GO:0006338 109 51 0,000 0,02510781 0,02845472 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,02510781 0,02844133 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,02510781 0,02842794 ! vesicle organization GO:0016050 107 51 0,000 0,02510781 0,02841457 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,02510781 0,02840121 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 0,000 0,02510781 0,02838787 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,02510781 0,02837453 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,02559418 0,02891061 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,02559418 0,02889704 ! membrane fusion GO:0006944 110 52 0,000 0,02559418 0,02888349 ! positive regulation of growth GO:0045927 90 52 0,000 0,02559418 0,02886995 ! covalent chromatin modification GO:0016569 101 52 0,000 0,02559418 0,02885642 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,02559418 0,0288429 ! amino acid activation GO:0043038 92 52 0,000 0,02559418 0,0288294 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,02559418 0,02881591 ! synapse organization GO:0050808 85 52 0,000 0,02559418 0,02880243 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,02608033 0,0293358 ! RNA catabolic process GO:0006401 93 53 0,000 0,02608033 0,02932209 ! regulation of translational initiation GO:0006446 82 53 0,000 0,02608033 0,0293084 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,02608033 0,02929471 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,02608033 0,02928104 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,02608033 0,02926739 ! cell maturation GO:0048469 100 53 0,000 0,02608033 0,02925374 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,02608033 0,02924011 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,02608033 0,02922649 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,02656625 0,02975717 GO:0010863|positive regulation of phospholipase C activity, ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,02656625 0,02974333 ! cell recognition GO:0008037 85 54 0,000 0,02656625 0,02972949 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,02656625 0,02971567 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,02656625 0,02970186 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,02656625 0,02968807 ! chloride transport GO:0006821 90 55 0,000 0,02705195 0,0302168 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,02705195 0,03020278 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,02705195 0,03018877 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,02705195 0,03017478 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,02705195 0,03016079 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,02705195 0,03014682 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,02705195 0,03013287 ! aging GO:0007568 103 55 0,000 0,02705195 0,03011892 ! gastrulation GO:0007369 112 55 0,000 0,02705195 0,03010499 ! heart morphogenesis GO:0003007 97 55 0,000 0,02705195 0,03009107 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,02705195 0,03007717 ! RNA elongation GO:0006354 79 55 0,000 0,02705195 0,03006328 ! nuclear export GO:0051168 97 55 0,000 0,02705195 0,0300494 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,02705195 0,03003553 ! regulation of actin filament length GO:0030832 105 56 0,000 0,02753742 0,03056044 ! sensory perception of smell GO:0007608 80 56 0,000 0,02753742 0,03054635 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,02753742 0,03053227 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,02753742 0,03051821 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,02753742 0,03050416 ! regulation of DNA replication GO:0006275 101 56 0,000 0,02753742 0,03049012 ! proton transport GO:0015992 94 56 0,000 0,02753742 0,0304761 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,02753742 0,03046209 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,02802267 0,03098462 ! muscle fiber development GO:0048747 112 57 0,000 0,02802267 0,03097039 ! positive regulation of cell migration GO:0030335 126 57 0,000 0,02802267 0,03095617 ! lipid modification GO:0030258 97 57 0,000 0,02802267 0,03094196 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,02802267 0,03092777 ! regulation of intracellular transport GO:0032386 101 57 0,000 0,02802267 0,03091359 ! maintenance of location GO:0051235 118 57 0,000 0,02802267 0,03089942 ! hydrogen transport GO:0006818 97 58 0,000 0,02850768 0,03141983 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,02850768 0,03140544 ! regulation of endocytosis GO:0030100 91 58 0,000 0,02850768 0,03139107 ! adult behavior GO:0030534 99 58 0,000 0,02850768 0,03137671 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,02850768 0,03136236 ! positive regulation of secretion GO:0051047 95 59 0,000 0,02899248 0,03188112 ! regulation of cellular component size GO:0032535 109 59 0,000 0,02899248 0,03186656 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,02899248 0,03185201 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,02899248 0,03183747 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,02899248 0,03182295 ! DNA catabolic process GO:0006308 86 59 0,000 0,02899248 0,03180844 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,02899248 0,03179394 ! establishment of organelle localization GO:0051656 109 59 0,000 0,02899248 0,03177945 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,02947704 0,03229589 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,02947704 0,03228119 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,02947704 0,0322665 ! regulation of heart contraction GO:0008016 110 60 0,000 0,02947704 0,03225183 ! camera-type eye development GO:0043010 116 60 0,000 0,02947704 0,03223717 ! protein amino acid autophosphorylation GO:0046777 141 60 0,000 0,02947704 0,03222252 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,02947704 0,03220789 ! kidney development GO:0001822 122 60 0,000 0,02947704 0,03219327 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,02996139 0,03270739 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,02996139 0,03269256 ! mesoderm development GO:0007498 119 61 0,000 0,02996139 0,03267774 ! tRNA processing GO:0008033 89 61 0,000 0,02996139 0,03266293 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,02996139 0,03264814 ! response to peptide hormone stimulus GO:0043434 122 61 0,000 0,02996139 0,03263336 ! ear development GO:0043583 103 62 0,000 0,0304455 0,03314565 ! viral reproductive process GO:0022415 126 62 0,000 0,0304455 0,03313065 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,0304455 0,03311568 ! gonad development GO:0008406 98 62 0,000 0,0304455 0,03310071 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,0304455 0,03308576 ! regulation of mitosis GO:0007088 105 63 0,000 0,03092939 0,03359644 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,03092939 0,03358128 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,03092939 0,03356613 ! detection of external stimulus GO:0009581 91 63 0,000 0,03092939 0,033551 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,03092939 0,03353588 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,03092939 0,03352077 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,03141306 0,03402963 ! cell redox homeostasis GO:0045454 102 64 0,000 0,03141306 0,03401432 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,03141306 0,03399902 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,03141306 0,03398373 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,03141306 0,03396846 ! positive regulation of cell motion GO:0051272 146 64 0,000 0,03141306 0,0339532 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,0318965 0,03446025 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,0318965 0,03444478 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,0318965 0,03442933 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,0318965 0,03441389 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,0318965 0,03439846 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,03237971 0,03490393 ! actin filament organization GO:0007015 148 66 0,000 0,03237971 0,0348883 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,03237971 0,03487269 ! extracellular matrix organization GO:0030198 133 66 0,000 0,03237971 0,03485708 ! secondary metabolic process GO:0019748 116 66 0,000 0,03237971 0,03484149 ! developmental maturation GO:0021700 116 66 0,000 0,03237971 0,03482592 ! cell projection assembly GO:0030031 120 66 0,000 0,03237971 0,03481036 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,0328627 0,03531382 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,0328627 0,03529806 ! negative regulation of protein kinase activity GO:0006469 130 67 0,000 0,0328627 0,03528231 ! negative regulation of cell growth GO:0030308 132 67 0,000 0,0328627 0,03526657 ! activation of MAPK activity GO:0000187 115 67 0,000 0,0328627 0,03525085 ! lung development GO:0030324 144 67 0,000 0,0328627 0,03523514 ! chromosome segregation GO:0007059 113 67 0,000 0,0328627 0,03521944 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,0328627 0,03520376 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,0328627 0,0351881 ! hexose catabolic process GO:0019320 104 67 0,000 0,0328627 0,03517244 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,0328627 0,0351568 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,0328627 0,03514118 ! adaptive immune response GO:0002250 119 67 0,000 0,0328627 0,03512557 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,0328627 0,03510997 ! amino acid transport GO:0006865 125 68 0,000 0,03334546 0,03560993 ! negative regulation of kinase activity GO:0033673 131 68 0,000 0,03334546 0,03559414 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,03334546 0,03557835 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,03334546 0,03556258 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,03334546 0,03554682 ! viral reproduction GO:0016032 134 68 0,000 0,03334546 0,03553108 ! regulation of lipase activity GO:0060191 130 68 0,000 0,03334546 0,03551535 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,03334546 0,03549964 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,033828 0,03599742 ! negative regulation of cell size GO:0045792 134 69 0,000 0,033828 0,03598151 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,033828 0,03596561 ! urogenital system development GO:0001655 137 69 0,000 0,033828 0,03594972 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,033828 0,03593385 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,033828 0,03591799 ! antigen processing and presentation GO:0019882 104 69 0,000 0,033828 0,03590215 ! appendage morphogenesis GO:0035107 135 70 0,000 0,03431032 0,03639798 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 0,000 0,03431032 0,03638194 ! amine catabolic process GO:0009310 117 71 0,000 0,03479241 0,03687688 ! reproductive structure development GO:0048608 113 71 0,000 0,03479241 0,03686065 ! appendage development GO:0048736 136 71 0,000 0,03479241 0,03684442 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,03479241 0,03682821 ! B cell activation GO:0042113 160 71 0,000 0,03479241 0,03681202 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,03479241 0,03679584 ! regulation of immune effector process GO:0002697 137 71 0,000 0,03479241 0,03677967 ! acute inflammatory response GO:0002526 113 72 0,000 0,03527427 0,03727268 ! regulation of caspase activity GO:0043281 122 72 0,000 0,03527427 0,03725632 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,03527427 0,03723997 ! carbohydrate transport GO:0008643 110 72 0,000 0,03527427 0,03722364 ! negative regulation of transferase activity GO:0051348 140 72 0,000 0,03527427 0,03720732 ! respiratory system development GO:0060541 153 72 0,000 0,03527427 0,03719101 ! learning or memory GO:0007611 147 73 0,000 0,03575591 0,03768231 ! regulation of blood pressure GO:0008217 125 73 0,000 0,03575591 0,03766582 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,03575591 0,03764933 ! axon guidance GO:0007411 139 73 0,000 0,03575591 0,03763286 ! fertilization GO:0009566 90 73 0,000 0,03575591 0,03761641 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,03623733 0,03810621 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,03623733 0,03808956 ! neurotransmitter transport GO:0006836 123 74 0,000 0,03623733 0,03807293 ! exocytosis GO:0006887 133 74 0,000 0,03623733 0,03805631 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,03623733 0,03803971 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,03623733 0,03802312 ! regulation of endopeptidase activity GO:0052548 125 74 0,000 0,03623733 0,03800654 ! eye development GO:0001654 143 74 0,000 0,03623733 0,03798998 ! organelle localization GO:0051640 136 74 0,000 0,03623733 0,03797344 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,03671852 0,03846093 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,03671852 0,03844419 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,03671852 0,03842747 ! rhythmic process GO:0048511 128 75 0,000 0,03671852 0,03841076 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,03671852 0,03839407 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,03719949 0,03888009 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,03719949 0,03886321 ! defense response to bacterium GO:0042742 89 76 0,000 0,03719949 0,03884634 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,03719949 0,03882949 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,03719949 0,03881265 ! regulation of catabolic process GO:0009894 161 76 0,000 0,03719949 0,03879582 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,03768023 0,03928017 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,03768023 0,03926316 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,03768023 0,03924616 ! blood coagulation GO:0007596 146 78 0,000 0,03816075 0,03972945 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,03816075 0,03971227 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,03816075 0,0396951 ! protein oligomerization GO:0051259 139 78 0,000 0,03816075 0,03967794 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,03864104 0,04015998 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,03864104 0,04014264 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,03864104 0,04012531 ! regulation of peptidase activity GO:0052547 134 79 0,000 0,03864104 0,040108 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,03864104 0,04009071 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,03912112 0,04057129 ! muscle cell differentiation GO:0042692 159 80 0,000 0,03912112 0,04055381 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,03912112 0,04053635 ! protein import into nucleus GO:0006606 158 80 0,000 0,03912112 0,0405189 ! inorganic anion transport GO:0015698 138 80 0,000 0,03912112 0,04050146 ! T cell activation GO:0042110 168 81 0,000 0,03960096 0,04098061 ! response to hypoxia GO:0001666 171 81 0,000 0,03960096 0,04096299 ! digestion GO:0007586 112 81 0,000 0,03960096 0,04094539 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,03960096 0,0409278 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,03960096 0,04091023 ! nuclear import GO:0051170 161 81 0,000 0,03960096 0,04089267 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,03960096 0,04087513 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,04008059 0,04135244 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,04008059 0,04133472 ! response to drug GO:0042493 143 82 0,000 0,04008059 0,04131701 ! response to nutrient GO:0007584 125 82 0,000 0,04008059 0,04129931 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,04008059 0,04128163 ! cellular response to hormone stimulus GO:0032870 167 82 0,000 0,04008059 0,04126397 ! response to oxygen levels GO:0070482 176 83 0,000 0,04055999 0,04173966 ! regulation of lyase activity GO:0051339 160 83 0,000 0,04055999 0,04172182 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,04103916 0,04219668 ! hemostasis GO:0007599 158 84 0,000 0,04103916 0,04217865 ! negative regulation of transport GO:0051051 153 84 0,000 0,04103916 0,04216064 ! negative regulation of growth GO:0045926 155 84 0,000 0,04103916 0,04214265 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,04103916 0,04212467 ! nucleosome assembly GO:0006334 122 85 0,000 0,04151812 0,04259812 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,04151812 0,04257996 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,04151812 0,04256182 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,04199685 0,04303425 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,04199685 0,04301593 ! chromatin assembly GO:0031497 124 86 0,000 0,04199685 0,04299762 ! tube morphogenesis GO:0035239 176 86 0,000 0,04199685 0,04297933 ! mitochondrion organization GO:0007005 148 86 0,000 0,04199685 0,04296106 ! alcohol catabolic process GO:0046164 130 86 0,000 0,04199685 0,0429428 ! amine transport GO:0015837 155 86 0,000 0,04199685 0,04292456 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,04247536 0,0433952 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,04247536 0,04337678 ! protein localization in nucleus GO:0034504 176 87 0,000 0,04247536 0,04335838 ! regulation of protein transport GO:0051223 154 87 0,000 0,04247536 0,04333999 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 135 88 0,000 0,04295364 0,04380943 ! regulation of DNA binding GO:0051101 155 88 0,000 0,04295364 0,04379087 ! gland development GO:0048732 206 88 0,000 0,04295364 0,04377232 ! regulation of neurological system process GO:0031644 148 88 0,000 0,04295364 0,04375379 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,04295364 0,04373528 ! cellular defense response GO:0006968 114 89 0,000 0,0434317 0,04420333 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,0434317 0,04418464 ! regulation of cell adhesion GO:0030155 212 89 0,000 0,0434317 0,04416596 ! ossification GO:0001503 188 90 0,000 0,04390954 0,04463302 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,04390954 0,04461417 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,04390954 0,04459534 ! sex differentiation GO:0007548 145 90 0,000 0,04390954 0,04457652 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,04390954 0,04455772 ! bone development GO:0060348 189 91 0,000 0,04438715 0,04502339 ! sterol metabolic process GO:0016125 152 91 0,000 0,04438715 0,04500442 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,04438715 0,04498546 ! regulation of defense response GO:0031347 149 92 0,000 0,04486455 0,04545015 ! nucleosome organization GO:0034728 138 92 0,000 0,04486455 0,04543102 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,04486455 0,04541191 ! vitamin metabolic process GO:0006766 139 92 0,000 0,04486455 0,04539281 ! positive regulation of MAP kinase activity GO:0043406 160 93 0,000 0,04534172 0,04585631 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,04534172 0,04583705 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,04534172 0,04581779 ! regulation of membrane potential GO:0042391 164 93 0,000 0,04534172 0,04579856 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,04534172 0,04577934 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,04581866 0,04624149 ! female pregnancy GO:0007565 164 94 0,000 0,04581866 0,0462221 ! transcription initiation GO:0006352 153 94 0,000 0,04581866 0,04620273 ! regulation of T cell activation GO:0050863 158 94 0,000 0,04581866 0,04618337 ! forebrain development GO:0030900 188 95 0,000 0,04629539 0,04664435 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,04629539 0,04662482 ! leukocyte differentiation GO:0002521 202 96 0,000 0,04677189 0,04708501 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,04677189 0,04706532 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,04677189 0,04704564 ! positive regulation of immune response GO:0050778 156 96 0,000 0,04677189 0,04702598 ! detection of stimulus GO:0051606 151 96 0,000 0,04677189 0,04700634 ! regulation of DNA metabolic process GO:0051052 178 97 0,000 0,04724817 0,04746518 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,04724817 0,04744537 ! protein ubiquitination GO:0016567 217 97 0,000 0,04724817 0,04742558 ! hormone metabolic process GO:0042445 157 97 0,000 0,04724817 0,0474058 ! regulation of protein localization GO:0032880 176 97 0,000 0,04724817 0,04738604 ! response to virus GO:0009615 160 98 0,000 0,04772423 0,04784354 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,04772423 0,04782362 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,04772423 0,04780371 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,04820007 0,04826024 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,04820007 0,04824017 ! skeletal muscle tissue development GO:0007519 186 99 0,000 0,04820007 0,04822011 GO:0060538|skeletal muscle organ development, ! cell cycle arrest GO:0007050 213 100 0,000 0,04867568 0,04867568